First year doctors experience of work related wellbeing and implications for educational provision

PubMed Central

2014-01-01

Objectives: To explore factors which affect newly qualified doctors’ wellbeing and look at the implications for educational provision. Methods Data were collected by free association narrative interviews of nine Foundation doctors and analysed using a grounded theory approach. Two Foundation programme directors were interviewed to verify data validity. Results Two main themes emerged: newly qualified doctors’ wellbeing is affected by 1) personal experience and 2) work related factors. They start work feeling unprepared by medical school, work experience (“shadowing”) or induction programmes at the beginning of the post. Senior colleague support and feedback are much valued but often lacking with little discussion of critical incidents and difficult issues. Challenges include sick patients, prescribing, patient/relative communication and no consistent team structure. Working shift patterns affects personal and social life. Enjoyment and reward come from helping patients, feelings of making a difference or teaching medical students. Conclusions Whilst becoming familiar with their roles, newly qualified doctors search for identity and build up resilience. The support given during this process affects their wellbeing including coping with day to day challenges, whether posts are experienced as rewarding and how work influences their personal and social lives. PMID:25341219

Orbitofrontal sulcogyral patterns are related to temperamental risk for psychopathology.

PubMed

Whittle, Sarah; Bartholomeusz, Cali; Yücel, Murat; Dennison, Meg; Vijayakumar, Nandita; Allen, Nicholas B

2014-02-01

There are marked individual differences in the pattern of cortical (sulcogyral) folding in the orbitofrontal cortex (OFC), and there is a growing literature suggesting that these individual differences are associated with risk for psychotic disorders. To date, however, no study has investigated whether OFC folding patterns are associated with broader risk factors relevant to a range of psychopathology. This study helps address this knowledge gap by examining whether OFC sulcogyral folding patterns are associated with putative risk factors, specifically affective temperament and psychiatric symptoms, in a large community sample (N = 152) of adolescents. Results showed that the most common pattern of folding ('Type I', marked by discontinuity of the medial orbital sulcus and continuity of the lateral orbital sulcus) was associated with low levels of Surgency, high levels of Negative Affectivity (in girls) and higher depressive symptoms. This pattern was also associated with reduced thickness of OFC gray matter. Overall, the findings, combined with previous work, suggest some specificity of neurodevelopmental risk for different types of psychopathology. Thus, these results have the potential to inform the early identification of at-risk individuals.

20 CFR 628.515 - Objective assessment.

Code of Federal Regulations, 2010 CFR

2010-04-01

... aptitudes for nontraditional occupations), attitude towards work, motivation, behavior patterns affecting... appropriate means to measure skills, abilities, attitudes, and interests of the participants. The methods used... and/or attitude inventories, career guidance instruments, aptitude tests, and basic skills tests. (2...

Work and family conflict in academic science: patterns and predictors among women and men in research universities.

PubMed

Fox, Mary Frank; Fonseca, Carolyn; Bao, Jinghui

2011-10-01

This article addresses work-family conflict as reported among women and men academic scientists in data systematically collected across fields of study in nine US research universities. Arguing that academic science is a particularly revealing case for studying work-family conflict, the article addresses: (1) the bi-directional conflict of work with family, and family with work, reported among the scientists; (2) the ways that higher, compared with lower, conflict, is predicted by key features of family, academic rank, and departments/institutions; and (3) patterns and predictors of work-family conflict that vary, as well as converge, by gender. Results point to notable differences, and commonalties, by gender, in factors affecting interference in both directions of work-family conflict reported by scientists. These findings have implications for understandings of how marriage and children, senior compared with junior academic rank, and departmental climates shape work-family conflict among women and men in US academic science.

Trustworthiness and Negative Affect Predict Economic Decision-Making.

PubMed

Nguyen, Christopher M; Koenigs, Michael; Yamada, Torricia H; Teo, Shu Hao; Cavanaugh, Joseph E; Tranel, Daniel; Denburg, Natalie L

2011-09-01

The Ultimatum Game (UG) is a widely used and well-studied laboratory model of economic decision-making. Here, we studied 129 healthy adults and compared demographic (i.e., age, gender, education), cognitive (i.e., intelligence, attention/working memory, speed, language, visuospatial, memory, executive functions), and personality (i.e., "Big Five", positive affect, negative affect) variables between those with a "rational" versus an "irrational" response pattern on the UG. Our data indicated that participants with "rational" UG performance (accepting any offer, no matter the fairness) endorsed higher levels of trust, or the belief in the sincerity and good intentions of others, while participants with "irrational" UG performance (rejecting unfair offers) endorsed higher levels of negative affect, such as anger and contempt. These personality variables were the only ones that differentiated the two response patterns-demographic and cognitive factors did not differ between rational and irrational players. The results indicate that the examination of personality and affect is crucial to our understanding of the individual differences that underlie decision-making.

Working after a metastatic cancer diagnosis: Factors affecting employment in the metastatic setting from ECOG-ACRIN's Symptom Outcomes and Practice Patterns study.

PubMed

Tevaarwerk, Amye J; Lee, Ju-Whei; Terhaar, Abigail; Sesto, Mary E; Smith, Mary Lou; Cleeland, Charles S; Fisch, Michael J

2016-02-01

Improved survival for individuals with metastatic cancer accentuates the importance of employment for cancer survivors. A better understanding of how metastatic cancer affects employment is a necessary step toward the development of tools for assisting survivors in this important realm. The ECOG-ACRIN Symptom Outcomes and Practice Patterns study was analyzed to investigate what factors were associated with the employment of 680 metastatic cancer patients. Univariate and multivariate logistic regression analyses were conducted to compare patients stably working with patients no longer working. There were 668 metastatic working-age participants in the analysis: 236 (35%) worked full- or part-time, whereas 302 (45%) had stopped working because of illness. Overall, 58% reported some change in employment due to illness. A better performance status and non-Hispanic white ethnicity/race were significantly associated with continuing to work despite a metastatic cancer diagnosis in the multivariate analysis. The disease type, time since metastatic diagnosis, number of metastatic sites, location of metastatic disease, and treatment status had no significant impact. Among the potentially modifiable factors, receiving hormonal treatment (if a viable option) and decreasing symptom interference were associated with continuing to work. A significant percentage of the metastatic patients remained employed; increased symptom burden was associated with a change to no longer working. Modifiable factors resulting in work interference should be minimized so that patients with metastatic disease may continue working if this is desired. Improvements in symptom control and strategies developed to help address workplace difficulties have promise for improving this aspect of survivorship. © 2015 American Cancer Society.

Job Sharing Through Part Time Contracts. A Consideration in the Context of Declining School Enrolments in Ontario.

ERIC Educational Resources Information Center

Kumar, Krishna

Two questionnaires were sent to all school boards and a sample of teachers in Ontario to assess how receptive boards and teachers are to job sharing as an alternative work pattern in schools affected by declining enrollment. The report gives the background of the concept of job sharing and an analysis of the benefits, work situations, and problems…

Effects of Creative and Non-Creative Work on the Tendency To Drink Alcohol during the Restitution Phase of the Creative Process.

ERIC Educational Resources Information Center

Gustafson, Roland; Norlander, Torsten

1995-01-01

This study examined how type of task affected 42 subjects' drinking patterns. Results indicated that subjects who had completed light creative work drank more alcohol than those in noncreative tasks, and participants completing hard creative tasks drank more of both alcoholic and nonalcoholic fluids. Results are discussed in terms of the need to…

Unusual Outbreak of Clinical Mastitis in Dairy Sheep Caused by Streptococcus equi subsp. zooepidemicus

PubMed Central

Las Heras, Alfonso; Vela, Ana I.; Fernández, Elena; Legaz, Emilio; Domínguez, Lucas; Fernández-Garayzábal, Jose F.

2002-01-01

This work describes an outbreak of clinical mastitis affecting 13 of 58 lactating ewes due to Streptococcus equi subsp. zooepidemicus. S. equi subsp. zooepidemicus was isolated in pure culture from all milk samples. All the clinical isolates had identical biochemical profiles and antimicrobial susceptibility patterns and also exhibited indistinguishable macrorestriction patterns by pulsed-field gel electrophoresis, indicating that all cases of mastitis were produced by a single strain. PMID:11880454

Dependence of B1+ and B1- Field Patterns of Surface Coils on the Electrical Properties of the Sample and the MR Operating Frequency.

PubMed

Vaidya, Manushka V; Collins, Christopher M; Sodickson, Daniel K; Brown, Ryan; Wiggins, Graham C; Lattanzi, Riccardo

2016-02-01

In high field MRI, the spatial distribution of the radiofrequency magnetic ( B 1 ) field is usually affected by the presence of the sample. For hardware design and to aid interpretation of experimental results, it is important both to anticipate and to accurately simulate the behavior of these fields. Fields generated by a radiofrequency surface coil were simulated using dyadic Green's functions, or experimentally measured over a range of frequencies inside an object whose electrical properties were varied to illustrate a variety of transmit [Formula: see text] and receive [Formula: see text] field patterns. In this work, we examine how changes in polarization of the field and interference of propagating waves in an object can affect the B 1 spatial distribution. Results are explained conceptually using Maxwell's equations and intuitive illustrations. We demonstrate that the electrical conductivity alters the spatial distribution of distinct polarized components of the field, causing "twisted" transmit and receive field patterns, and asymmetries between [Formula: see text] and [Formula: see text]. Additionally, interference patterns due to wavelength effects are observed at high field in samples with high relative permittivity and near-zero conductivity, but are not present in lossy samples due to the attenuation of propagating EM fields. This work provides a conceptual framework for understanding B 1 spatial distributions for surface coils and can provide guidance for RF engineers.

An Ongoing Revolution: Resource Sharing and OCLC.

ERIC Educational Resources Information Center

Nevins, Kate

1998-01-01

Discusses early developments in the Online Computer Library Center (OCLC) interlibrary loan, including use of OCLC for verification and request transmittal, improved service to patrons, internal cost control, affect on work flow and borrowing patterns. Describes advances in OCLC, including internationalization, electronic information access,…

Working after a metastatic cancer diagnosis: factors affecting employment in the metastatic setting from ECOG’s Symptom Outcomes and Practice Patterns (SOAPP) study

PubMed Central

Tevaarwerk, Amye; Lee, Ju-Whei; Terhaar, Abigail; Sesto, Mary; Smith, Mary Lou; Cleeland, Charles; Fisch, Michael

2015-01-01

Background Improved survival for individuals with metastatic cancer accentuates the importance of employment for cancer survivors. Better understanding of how metastatic cancer affects employment is a necessary step towards the development of tools to assist survivors in this important realm. Methods We analyzed the Eastern Cooperative Oncology Group’s “Symptom Outcomes and Practice Patterns (SOAPP)” study to investigate what factors were associated with employment of 680 metastatic cancer patients. Univariable and multivariable logistic regression analyses were conducted to compare patients stably working (Group A) to patients no longer working (Group B). Results There were 668 metastatic working-age participants in our analysis; 236 (35%) worked full or part-time while 302 (45%) stopped working due to illness. Overall, 58% reported some change in employment due to illness. Better performance status and non-Hispanic White ethnicity/race were significantly associated with continuing to work despite a metastatic cancer diagnosis on multivariable analysis. Disease type, time since metastatic diagnosis, number of metastatic sites, location of metastatic disease, and treatment status had no significant impact. Among the potentially modifiable factors, receiving hormonal treatment (if a viable option) and decreasing symptom interference were associated with continuing to work. Conclusions A significant percentage of metastatic patients remain employed; symptom burden was associated with change to no longer working. Modifiable factors resulting in work interference should be minimized so that patients with metastatic disease may continue working, if desired. Improvements in symptom control and strategies developed to help address work place difficulties have promise to improve this aspect of survivorship. PMID:26687819

Model uncertainties do not affect observed patterns of species richness in the Amazon.

PubMed

Sales, Lilian Patrícia; Neves, Olívia Viana; De Marco, Paulo; Loyola, Rafael

2017-01-01

Climate change is arguably a major threat to biodiversity conservation and there are several methods to assess its impacts on species potential distribution. Yet the extent to which different approaches on species distribution modeling affect species richness patterns at biogeographical scale is however unaddressed in literature. In this paper, we verified if the expected responses to climate change in biogeographical scale-patterns of species richness and species vulnerability to climate change-are affected by the inputs used to model and project species distribution. We modeled the distribution of 288 vertebrate species (amphibians, birds and mammals), all endemic to the Amazon basin, using different combinations of the following inputs known to affect the outcome of species distribution models (SDMs): 1) biological data type, 2) modeling methods, 3) greenhouse gas emission scenarios and 4) climate forecasts. We calculated uncertainty with a hierarchical ANOVA in which those different inputs were considered factors. The greatest source of variation was the modeling method. Model performance interacted with data type and modeling method. Absolute values of variation on suitable climate area were not equal among predictions, but some biological patterns were still consistent. All models predicted losses on the area that is climatically suitable for species, especially for amphibians and primates. All models also indicated a current East-western gradient on endemic species richness, from the Andes foot downstream the Amazon river. Again, all models predicted future movements of species upwards the Andes mountains and overall species richness losses. From a methodological perspective, our work highlights that SDMs are a useful tool for assessing impacts of climate change on biodiversity. Uncertainty exists but biological patterns are still evident at large spatial scales. As modeling methods are the greatest source of variation, choosing the appropriate statistics according to the study objective is also essential for estimating the impacts of climate change on species distribution. Yet from a conservation perspective, we show that Amazon endemic fauna is potentially vulnerable to climate change, due to expected reductions on suitable climate area. Climate-driven faunal movements are predicted towards the Andes mountains, which might work as climate refugia for migrating species.

Model uncertainties do not affect observed patterns of species richness in the Amazon

PubMed Central

Sales, Lilian Patrícia; Neves, Olívia Viana; De Marco, Paulo

2017-01-01

Background Climate change is arguably a major threat to biodiversity conservation and there are several methods to assess its impacts on species potential distribution. Yet the extent to which different approaches on species distribution modeling affect species richness patterns at biogeographical scale is however unaddressed in literature. In this paper, we verified if the expected responses to climate change in biogeographical scale—patterns of species richness and species vulnerability to climate change—are affected by the inputs used to model and project species distribution. Methods We modeled the distribution of 288 vertebrate species (amphibians, birds and mammals), all endemic to the Amazon basin, using different combinations of the following inputs known to affect the outcome of species distribution models (SDMs): 1) biological data type, 2) modeling methods, 3) greenhouse gas emission scenarios and 4) climate forecasts. We calculated uncertainty with a hierarchical ANOVA in which those different inputs were considered factors. Results The greatest source of variation was the modeling method. Model performance interacted with data type and modeling method. Absolute values of variation on suitable climate area were not equal among predictions, but some biological patterns were still consistent. All models predicted losses on the area that is climatically suitable for species, especially for amphibians and primates. All models also indicated a current East-western gradient on endemic species richness, from the Andes foot downstream the Amazon river. Again, all models predicted future movements of species upwards the Andes mountains and overall species richness losses. Conclusions From a methodological perspective, our work highlights that SDMs are a useful tool for assessing impacts of climate change on biodiversity. Uncertainty exists but biological patterns are still evident at large spatial scales. As modeling methods are the greatest source of variation, choosing the appropriate statistics according to the study objective is also essential for estimating the impacts of climate change on species distribution. Yet from a conservation perspective, we show that Amazon endemic fauna is potentially vulnerable to climate change, due to expected reductions on suitable climate area. Climate-driven faunal movements are predicted towards the Andes mountains, which might work as climate refugia for migrating species. PMID:29023503

The effect of "countrywide services management law" on the work motivation of the employees of Iranian ministry of health.

PubMed

Shafeghat, Hossein; Jafari, Mehdi; Monavarian, Abbas; Shafayi, Maryam; Dehnavieh, Reza

2014-02-01

Labor laws and regulations have inevitable effects on employees' work motivation as well as the overall efficiency and productivity of the organization. This study was conducted to assess the effects of the "Countrywide Services Management Law" on the work motivation level of the employees of the Iranian Ministry of Health. This cross-sectional study was done in 2011 in the Iran's Ministry of Health. Data was collected by a 51-item Likert scale questionnaire, in five domains including: organizational structure, information technology, training patterns, salary and bonus system and re-engineering process. The reliability and validity of the questionnaire was evaluated (Cronbach's alpha= 0.96). Data analysis was conducted using descriptive and inferential statistics (t-test). Out of 192 samples examined, 55.2% of the respondents were female, 88 (45.8%) had BS degree and 116 (60.4%) had less than 10 years' experience. The mean scores in the domains of organizational structure, information technology, training patterns, salary and bonus system and re-engineering patterns were: 3.11, 3.51, 3.05, 3.21 and 3.14, respectively. Relationship between the items related to manpower in the "Countrywide Services Management Law", with employees' work motivation was significant (P < 0.0001). The training patterns did not show a significant relation (P < 0.26) with any of five domains. According to our results and the views of the employees of the Iranian Ministry of Health, "Countrywide Services Management Law" positively affected the personnel's work motivation regarding all the factors associated with motivation including: organizational structure, information technology, training patterns, salary and bonus system and re-engineering pattern. Finally, to enhance the workforce motivation and satisfaction level, application and implementation of the rules and regulations should be based on the organizational needs.

Associations of long-term shift work with waking salivary cortisol concentration and patterns among police officers.

PubMed

Fekedulegn, Desta; Burchfiel, Cecil M; Violanti, John M; Hartley, Tara A; Charles, Luenda E; Andrew, Michael E; Miller, Diane B

2012-01-01

The objective of this study was to evaluate whether long-term shift work is associated with both the total hormonal secretion after awakening and the pattern of the cortisol levels during the first hour following awakening, among 65 randomly selected police officers who represent a high stress occupation. Dominant shift (Day, Afternoon, or Midnight) was ascertained using daily payroll records of each participant's work activities during the 6-8 yrs prior to saliva sampling. Four salivary samples were collected at 15 min intervals upon first awakening. After accounting for potential confounders, salivary cortisol concentrations averaged across all four time points and total area under the curve differed significantly across shift with midnight shift workers showing suppressed awakening cortisol response relative to the afternoon and day shift. The percent of hours worked on midnight shift was inversely correlated with total awakening cortisol output. In contrast, the pattern of cortisol secretion during the first hour following waking appeared not to be affected as no significant interaction effect was found between time since awakening and shift work. The results show that long-term midnight shift work is associated with decreased absolute mean level and total volume of cortisol released over the waking period.

Associations of Long-term Shift Work with Waking Salivary Cortisol Concentration and Patterns among Police Officers

PubMed Central

FEKEDULEGN, Desta; BURCHFIEL, Cecil M.; VIOLANTI, John M.; HARTLEY, Tara A.; CHARLES, Luenda E.; ANDREW, Michael E.; MILLER, Diane B.

2015-01-01

The objective of this study was to evaluate whether long-term shift work is associated with both the total hormonal secretion after awakening and the pattern of the cortisol levels during the first hour following awakening, among 65 randomly selected police officers who represent a high stress occupation. Dominant shift (Day, Afternoon, or Midnight) was ascertained using daily payroll records of each participant’s work activities during the 6–8 yrs prior to saliva sampling. Four salivary samples were collected at 15 min intervals upon first awakening. After accounting for potential confounders, salivary cortisol concentrations averaged across all four time points and total area under the curve differed significantly across shift with midnight shift workers showing suppressed awakening cortisol response relative to the afternoon and day shift. The percent of hours worked on midnight shift was inversely correlated with total awakening cortisol output. In contrast, the pattern of cortisol secretion during the first hour following waking appeared not to be affected as no significant interaction effect was found between time since awakening and shift work. The results show that long-term midnight shift work is associated with decreased absolute mean level and total volume of cortisol released over the waking period. PMID:23047078

Practice Patterns and Job Satisfaction of Mohs Surgeons.

PubMed

Kohli, Nita; Golda, Nicholas

2018-01-01

There is a paucity of data on Mohs surgery workforce patterns. To identify if gender differences exist in practice patterns of Mohs surgeons, factors that influence these differences, and factors influencing job satisfaction among Mohs surgeons. An electronic survey was distributed to dermatology organizations targeting members of the American College of Mohs Surgery (ACMS), from October 2015 to April 2016. Two hundred twenty-seven ACMS members responded; 37% were women. Twenty-five percent of women and 19% of men work part time. Thirty-seven percent of women practice in academia versus 22% of men. Forty-three percent of women and 23% of men identified children as a factor affecting their ability to work full time. Gender comparisons for current job satisfaction show 57% of men and 35% of women being very satisfied. Supervision/feedback/recognition adds to satisfaction at a higher rate for women (53%) than for men (29%). For both genders combined, work content, patient base, and autonomy had the highest average job satisfaction ratings. Gender differences exist in practice patterns and job satisfaction of Mohs surgeons. This study demonstrates factors that could influence job satisfaction among female Mohs surgeons-knowledge that is important to individuals who lead, mentor, or supervise female Mohs surgeons.

Advance or Retreat? Early Childhood Services in the Eighties.

ERIC Educational Resources Information Center

Burns, Alisa

1981-01-01

Predicts that changing sociocultural patterns will affect services for Australian children in the 1980s. Among topics discussed are demographic changes: a decreased birth rate and an increased number of working mothers in fatherless families at the poverty level. Compensatory education programs and family policy development in Western societies…

Efficacy of Accent Modification Training for International Medical Professionals

ERIC Educational Resources Information Center

Khurana, Poonam; Huang, Edgar

2013-01-01

International medical graduates (IMGs) comprise 26% of the U.S. physician work force. While IMGs bring all their knowledge and expertise, their pronunciation and intonation patterns often become a barrier in their ability to be understood. This breakdown in communication can affect physician-patient or physician-staff understanding and hence…

Apprenticeships Should Work for Women Too!

ERIC Educational Resources Information Center

Simon, Linda; Clarke, Kira

2016-01-01

Purpose: The purpose of this paper is to explore some of the issues affecting successful employment outcomes for young women in male-dominated careers, focusing on those generally accessed via a traditional Australian apprenticeship model. Current patterns of participation in trades-based fields of education and training reinforce the highly…

Organizational Literacy for Educators. Topics in Educational Leadership.

ERIC Educational Resources Information Center

Earle, Jason; Kruse, Sharon D.

Teachers and administrators who understand the "politics" in schools can operate more successfully to facilitate change. This book teaches educators to identify and influence common social patterns that affect their work in school organizations. Chapter 1 provides an introduction to the concept of organizational literacy and an overview of several…

Modeling Student Learning Behavior Patterns in an Online Science Inquiry Environment

ERIC Educational Resources Information Center

Brenner, Daniel G.; Matlen, Bryan J.; Timms, Michael J.; Gochyyev, Perman; Grillo-Hill, Andrew; Luttgen, Kim; Varfolomeeva, Marina

2017-01-01

This study investigated how the frequency and level of assistance provided to students interacted with prior knowledge to affect learning in the "Voyage to Galapagos" ("VTG") science inquiry-learning environment. "VTG" provides students with the opportunity to do simulated science field work in Galapagos as they…

Error-Analysis for Correctness, Effectiveness, and Composing Procedure.

ERIC Educational Resources Information Center

Ewald, Helen Rothschild

The assumptions underpinning grammatical mistakes can often be detected by looking for patterns of errors in a student's work. Assumptions that negatively influence rhetorical effectiveness can similarly be detected through error analysis. On a smaller scale, error analysis can also reveal assumptions affecting rhetorical choice. Snags in the…

Media Use and School Achievement--Boys at Risk?

ERIC Educational Resources Information Center

Mossle, Thomas; Kleimann, Matthias; Rehbein, Florian; Pfeiffer, Christian

2010-01-01

In work done at the German Criminological Research Institute of Lower Saxony (KFN) various methods have been used to investigate how specific inappropriate media usage patterns affect academic performance in children and adolescents. The findings are paralleled by current international research indicating a negative relationship between these two…

Analysis of Thermo-Diffusive Cellular Instabilities in Continuum Combustion Fronts

NASA Astrophysics Data System (ADS)

Azizi, Hossein; Gurevich, Sebastian; Provatas, Nikolas; Department of Physics, Centre Physics of Materials Team

We explore numerically the morphological patterns of thermo-diffusive instabilities in combustion fronts with a continuum solid fuel source, within a range of Lewis numbers, focusing on the cellular regime. Cellular and dendritic instabilities are found at low Lewis numbers. These are studied using a dynamic adaptive mesh refinement technique that allows very large computational domains, thus allowing us to reduce finite size effects that can affect or even preclude the emergence of these patterns. The distinct types of dynamics found in the vicinity of the critical Lewis number. These types of dynamics are classified as ``quasi-linear'' and characterized by low amplitude cells that may be strongly affected by the mode selection mechanism and growth prescribed by the linear theory. Below this range of Lewis number, highly non-linear effects become prominent and large amplitude, complex cellular and seaweed dendritic morphologies emerge. The cellular patterns simulated in this work are similar to those observed in experiments of flame propagation over a bed of nano-aluminum powder burning with a counter-flowing oxidizer conducted by Malchi et al. It is noteworthy that the physical dimension of our computational domain is roughly close to their experimental setup. This work was supported by a Canadian Space Agency Class Grant ''Percolating Reactive Waves in Particulate Suspensions''. We thank Compute Canada for computing resources.

A method for assessing work productivity and flexibility in livestock farms.

PubMed

Hostiou, N; Dedieu, B

2012-05-01

Changes affecting livestock farming systems have made farm work a central concern for both the sector and for farmers themselves. Increased pressure on farms to be competitive and productive together with farmers' demand for greater autonomy, holidays or time to spend on private activities and the family converge to underline the two key dimensions of work - productivity and flexibility - required for the assessment of work organization. This paper proposes a method called the QuaeWork (QUAlification and Evaluation of Work in livestock farms) to assess work productivity and flexibility on a farm, and its use to identify how livestock management can contribute to work organization on dairy farms. The QuaeWork method was set up through an iterative process combining surveys conducted with farmers in two regions of France, discussions with different experts and literature review. The QuaeWork was applied on a sample of seven dairy farms in the southern Massif Central in France to identify patterns of how livestock management contributes to work organization. The QuaeWork was used to analyse work organization over the year through a systemic approach to the farm, integrating interactions between herd and land management, workforce composition, equipment facilities and combinations of activities through a characterization of 'who does what, when and for how long'. The criteria for assessing work productivity were work duration (routine work, seasonal work) and work efficiency (per livestock unit or hectare of utilized agricultural area). The criteria for assessing work flexibility were room for manoeuvre and adjustments to internal and external events. The three main patterns of livestock management practices to work organization were identified. In pattern-1, farmers used indoor stable feeding practices with delegated work, with moderate room for manoeuvre and efficiency. In pattern-3, farmers used simplified milking, reproduction and breeding practices to seasonalize work and make it efficient with consistent room for manoeuvre. The method suggests social sustainability criteria to assess work productivity and flexibility, which are important for making reasoned decisions on livestock farm changes, especially innovations. Researchers could usefully exploit the QuaeWork to integrate work objectives (productivity, flexibility) into technical and economic goals.

Inorganic resist materials based on zirconium phosphonate for atomic force microscope lithography

NASA Astrophysics Data System (ADS)

Kang, Mankyu; Kim, Seonae; Jung, JinHyuck; Kim, Heebom; Shin, Inkyun; Jeon, Chanuk; Lee, Haiwon

2014-03-01

New inorganic resist materials based on metal complexes were investigated for atomic force microscope (AFM) lithography. Phosphoric acids are good for self-assembly because of their strong binding energy. In this work, zirconium phosphonate system are newly synthesized for spin-coatable materials in aqueous solutions and leads to negative tone pattern for improving line edge roughness. Low electron exposure by AFM lithography could generate a pattern by electrochemical reaction and cross-linking of metal-oxo complexes. It has been reported that the minimum pattern results are affected by lithographic speed, and the applied voltage between a tip and a substrate.

Factors associated with less-than-full-time working in medical practice: results of surveys of five cohorts of UK doctors, 10 years after graduation.

PubMed

Lachish, Shelly; Svirko, Elena; Goldacre, Michael J; Lambert, Trevor

2016-10-13

The greater participation of women in medicine in recent years, and recent trends showing that doctors of both sexes work fewer hours than in the past, present challenges for medical workforce planning. In this study, we provide a detailed analysis of the characteristics of doctors who choose to work less-than-full-time (LTFT). We aimed to determine the influence of these characteristics on the probability of working LTFT. We used data on working patterns obtained from long-term surveys of 10,866 UK-trained doctors. We analysed working patterns at 10 years post-graduation for doctors of five graduating cohorts, 1993, 1996, 1999, 2000 and 2002 (i.e. in the years 2003, 2006, 2009, 2010 and 2012, respectively). We used multivariable binary logistic regression models to examine the influence of a number of personal and professional characteristics on the likelihood of working LTFT in male and female doctors. Across all cohorts, 42 % of women and 7 % of men worked LTFT. For female doctors, having children significantly increased the likelihood of working LTFT, with greater effects observed for greater numbers of children and for female doctors in non-primary care specialties (non-GPs). While >40 % of female GPs with children worked LTFT, only 10 % of female surgeons with children did so. Conversely, the presence of children had no effect on male working patterns. Living with a partner increased the odds of LTFT working in women doctors, but decreased the odds of LTFT working in men (independently of children). Women without children were no more likely to work LTFT than were men (with or without children). For both women and men, the highest rates of LTFT working were observed among GPs (~10 and 6 times greater than non-GPs, respectively), and among those not in training or senior positions. Family circumstances (children and partner status) affect the working patterns of women and men differently, but both sexes respond similarly to the constraints of their clinical specialty and seniority. Thus, although women doctors comprise the bulk of LTFT workers, gender is just one of several determinants of doctors' working patterns, and wanting to work LTFT is evidently not solely an issue for working mothers.

Noticing relevant problem features: activating prior knowledge affects problem solving by guiding encoding

PubMed Central

Crooks, Noelle M.; Alibali, Martha W.

2013-01-01

This study investigated whether activating elements of prior knowledge can influence how problem solvers encode and solve simple mathematical equivalence problems (e.g., 3 + 4 + 5 = 3 + __). Past work has shown that such problems are difficult for elementary school students (McNeil and Alibali, 2000). One possible reason is that children's experiences in math classes may encourage them to think about equations in ways that are ultimately detrimental. Specifically, children learn a set of patterns that are potentially problematic (McNeil and Alibali, 2005a): the perceptual pattern that all equations follow an “operations = answer” format, the conceptual pattern that the equal sign means “calculate the total”, and the procedural pattern that the correct way to solve an equation is to perform all of the given operations on all of the given numbers. Upon viewing an equivalence problem, knowledge of these patterns may be reactivated, leading to incorrect problem solving. We hypothesized that these patterns may negatively affect problem solving by influencing what people encode about a problem. To test this hypothesis in children would require strengthening their misconceptions, and this could be detrimental to their mathematical development. Therefore, we tested this hypothesis in undergraduate participants. Participants completed either control tasks or tasks that activated their knowledge of the three patterns, and were then asked to reconstruct and solve a set of equivalence problems. Participants in the knowledge activation condition encoded the problems less well than control participants. They also made more errors in solving the problems, and their errors resembled the errors children make when solving equivalence problems. Moreover, encoding performance mediated the effect of knowledge activation on equivalence problem solving. Thus, one way in which experience may affect equivalence problem solving is by influencing what students encode about the equations. PMID:24324454

Healthy occupational culture for a worker-friendly workplace.

PubMed

Grabovac, Igor; Mustajbegović, Jadranka

2015-03-01

Work has numerous health and wellbeing benefits, but it also involves physical hazards and psychological exertion. Today the scale has tipped toward psychosocial factors. Workers' mental health affects their intellectual, emotional, and social growth, as well as work ability, productivity, and ultimately organisational productivity and competitiveness on the market. Even though companies may have an internal hierarchy that lowers stress at work, there are other formal and informal social processes that can affect (positively or negatively) the cohesion within the work unit. Safety culture of an organisation is a product of individual and group values, opinions, competences, and behavioural patterns that determine how occupational health and safety are implemented. Organisations that nurture positive safety culture understand the importance of health and safety and believe in prevention rather than dealing with consequences. Jobs that are stable, autonomous, and reasonably physically and psychologically demanding are far more likely to lower work-related stress and boost worker satisfaction. In fact, employee empowerment is one of the best ways to achieve good psychosocial health at the workplace.

Frontal Electroencephalogram Asymmetry during Affective Processing in Children with Down Syndrome: A Pilot Study

ERIC Educational Resources Information Center

Conrad, N. J.; Schmidt, L. A.; Niccols, A.; Polak, C. P.; Riniolo, T. C.; Burack, J. A.

2007-01-01

Background: Although the pattern of frontal electroencephalogram (EEG) asymmetry during the processing of emotion has been examined in many studies of healthy adults and typically developing infants and children, no published work has used these theoretical and methodological approaches to study emotion processing in children with Down syndrome.…

Difficulties Encountered by Academicians in Academic Research Processes in Universities

ERIC Educational Resources Information Center

Yalçin, Sinan; Altun Yalçin, Sema

2017-01-01

This present research, aimed to determine the occasions, which the academicians encountered during the academic research process and how these affect the research process, was prepared as a case study pattern among the qualitative research methods. 34 academicians, who were working in a university in Turkey, participated in the research. The data…

Effects of tonal language background on tests of temporal sequencing in children.

PubMed

Mukari, Siti Zamratol-Mai S; Yu, Xuan; Ishak, Wan Syafira; Mazlan, Rafidah

2015-01-01

The aims of the present study were to determine the effects of language background on the performance of the pitch pattern sequence test (PPST) and duration pattern sequence test (DPST). As temporal order sequencing may be affected by age and working memory, these factors were also studied. Performance of tonal and non-tonal language speakers on PPST and DPST were compared. Twenty-eight native Mandarin (tonal language) speakers and twenty-nine native Malay (non-tonal language) speakers between seven to nine years old participated in this study. The results revealed that relative to native Malay speakers, native Mandarin speakers demonstrated better scores on the PPST in both humming and verbal labeling responses. However, a similar language effect was not apparent in the DPST. An age effect was only significant in the PPST (verbal labeling). Finally, no significant effect of working memory was found on the PPST and the DPST. These findings suggest that the PPST is affected by tonal language background, and highlight the importance of developing different normative values for tonal and non-tonal language speakers.

Effects of different electron donor feeding patterns on TCE reductive dechlorination performance.

PubMed

Panagiotakis, I; Antoniou, K; Mamais, D; Pantazidou, M

2015-03-01

This study investigates how the feeding pattern of e(-) donors might affect the efficiency of enhanced in situ bioremediation in TCE-contaminated aquifers. A series of lab-scale batch experiments were conducted using butyrate or hydrogen gas (H2) as e(-) donor and a TCE-dechlorinating microbial consortium dominated by Dehalococcoides spp. The results of these experiments demonstrate that butyrate is similarly efficient for TCE dechlorination whether it is injected once or in doses. Moreover, the present work indicates that the addition of butyrate in great excess cannot be avoided, since it most likely provide, even indirectly, significant part of the H2 required. Furthermore, methanogenesis appears to be the major ultimate e(-) accepting process in all experiments, regardless the e(-) donor used and the feeding pattern. Finally, the timing of injection of H2 seems to significantly affect dechlorination performance, since the injection during the early stages improves VC-to-ETH dechlorination and reduce methanogenic activity.

Integration of active pauses and pattern of muscular activity during computer work.

PubMed

St-Onge, Nancy; Samani, Afshin; Madeleine, Pascal

2017-09-01

Submaximal isometric muscle contractions have been reported to increase variability of muscle activation during computer work; however, other types of active contractions may be more beneficial. Our objective was to determine which type of active pause vs. rest is more efficient in changing muscle activity pattern during a computer task. Asymptomatic regular computer users performed a standardised 20-min computer task four times, integrating a different type of pause: sub-maximal isometric contraction, dynamic contraction, postural exercise and rest. Surface electromyographic (SEMG) activity was recorded bilaterally from five neck/shoulder muscles. Root-mean-square decreased with isometric pauses in the cervical paraspinals, upper trapezius and middle trapezius, whereas it increased with rest. Variability in the pattern of muscular activity was not affected by any type of pause. Overall, no detrimental effects on the level of SEMG during active pauses were found suggesting that they could be implemented without a cost on activation level or variability. Practitioner Summary: We aimed to determine which type of active pause vs. rest is best in changing muscle activity pattern during a computer task. Asymptomatic computer users performed a standardised computer task integrating different types of pauses. Muscle activation decreased with isometric pauses in neck/shoulder muscles, suggesting their implementation during computer work.

The Effect of “Countrywide Services Management Law” on the Work Motivation of the Employees of Iranian Ministry of Health

PubMed Central

Shafeghat, Hossein; Jafari, Mehdi; Monavarian, Abbas; Shafayi, Maryam; Dehnavieh, Reza

2014-01-01

Background: Labor laws and regulations have inevitable effects on employees’ work motivation as well as the overall efficiency and productivity of the organization. Objectives: This study was conducted to assess the effects of the “Countrywide Services Management Law” on the work motivation level of the employees of the Iranian Ministry of Health. Patients and Methods: This cross-sectional study was done in 2011 in the Iran's Ministry of Health. Data was collected by a 51-item Likert scale questionnaire, in five domains including: organizational structure, information technology, training patterns, salary and bonus system and re-engineering process. The reliability and validity of the questionnaire was evaluated (Cronbach's alpha= 0.96). Data analysis was conducted using descriptive and inferential statistics (t-test). Results: Out of 192 samples examined, 55.2% of the respondents were female, 88 (45.8%) had BS degree and 116 (60.4%) had less than 10 years’ experience. The mean scores in the domains of organizational structure, information technology, training patterns, salary and bonus system and re-engineering patterns were: 3.11, 3.51, 3.05, 3.21 and 3.14, respectively. Relationship between the items related to manpower in the “Countrywide Services Management Law”, with employees' work motivation was significant (P < 0.0001). The training patterns did not show a significant relation (P < 0.26) with any of five domains. Conclusions: According to our results and the views of the employees of the Iranian Ministry of Health, “Countrywide Services Management Law” positively affected the personnel's work motivation regarding all the factors associated with motivation including: organizational structure, information technology, training patterns, salary and bonus system and re-engineering pattern. Finally, to enhance the workforce motivation and satisfaction level, application and implementation of the rules and regulations should be based on the organizational needs. PMID:24719736

Frontal brain electrical activity (EEG) and heart rate in response to affective infant-directed (ID) speech in 9-month-old infants.

PubMed

Santesso, Diane L; Schmidt, Louis A; Trainor, Laurel J

2007-10-01

Many studies have shown that infants prefer infant-directed (ID) speech to adult-directed (AD) speech. ID speech functions to aid language learning, obtain and/or maintain an infant's attention, and create emotional communication between the infant and caregiver. We examined psychophysiological responses to ID speech that varied in affective content (i.e., love/comfort, surprise, fear) in a group of typically developing 9-month-old infants. Regional EEG and heart rate were collected continuously during stimulus presentation. We found the pattern of overall frontal EEG power was linearly related to affective intensity of the ID speech, such that EEG power was greatest in response to fear, than surprise than love/comfort; this linear pattern was specific to the frontal region. We also noted that heart rate decelerated to ID speech independent of affective content. As well, infants who were reported by their mothers as temperamentally distressed tended to exhibit greater relative right frontal EEG activity during baseline and in response to affective ID speech, consistent with previous work with visual stimuli and extending it to the auditory modality. Findings are discussed in terms of how increases in frontal EEG power in response to different affective intensity may reflect the cognitive aspects of emotional processing across sensory domains in infancy.

North Atlantic SST Patterns and NAO Flavors

NASA Astrophysics Data System (ADS)

Rousi, E.; Rahmstorf, S.; Coumou, D.

2017-12-01

North Atlantic SST variability results from the interaction of atmospheric and oceanic processes. The North Atlantic Oscillation (NAO) drives changes in SST patterns but is also driven by them on certain time-scales. These interactions are not very well understood and might be affected by anthropogenic climate change. Paleo reconstructions indicate a slowdown of the Atlantic Meridional Overturning Circulation (AMOC) in recent decades leading to a pronounced cold anomaly ("cold blob") in the North Atlantic (Rahmstorf et al., 2015). The latter may favor NAO to be in its negative mode. In this work, sea surface temperature (SST) patterns are studied in relation to NAO variations, with the aim of discovering preferred states and understanding their interactions. SST patterns are analyzed with Self-Organizing Maps (SOM), a clustering technique that helps identify different spatial patterns and their temporal evolution. NAO flavors refer to different longitudinal positions and tilts of the NAO action centers, also defined with SOMs. This way the limitations of the basic, index-based, NAO-definition are overcome, and the method handles different spatially shapes associated with NAO. Preliminary results show the existence of preferred combinations of SSTs and NAO flavors, which in turn affect weather and climate of Europe and North America. The possible influence of the cold blob on European weather is discussed.

Modeling eye gaze patterns in clinician-patient interaction with lag sequential analysis.

PubMed

Montague, Enid; Xu, Jie; Chen, Ping-Yu; Asan, Onur; Barrett, Bruce P; Chewning, Betty

2011-10-01

The aim of this study was to examine whether lag sequential analysis could be used to describe eye gaze orientation between clinicians and patients in the medical encounter. This topic is particularly important as new technologies are implemented into multiuser health care settings in which trust is critical and nonverbal cues are integral to achieving trust. This analysis method could lead to design guidelines for technologies and more effective assessments of interventions. Nonverbal communication patterns are important aspects of clinician-patient interactions and may affect patient outcomes. The eye gaze behaviors of clinicians and patients in 110 videotaped medical encounters were analyzed using the lag sequential method to identify significant behavior sequences. Lag sequential analysis included both event-based lag and time-based lag. Results from event-based lag analysis showed that the patient's gaze followed that of the clinician, whereas the clinician's gaze did not follow the patient's. Time-based sequential analysis showed that responses from the patient usually occurred within 2 s after the initial behavior of the clinician. Our data suggest that the clinician's gaze significantly affects the medical encounter but that the converse is not true. Findings from this research have implications for the design of clinical work systems and modeling interactions. Similar research methods could be used to identify different behavior patterns in clinical settings (physical layout, technology, etc.) to facilitate and evaluate clinical work system designs.

Understanding Activist Leadership Effort in the Movement Opposing Drinking and Driving

ERIC Educational Resources Information Center

Dorius, Cassandra R.; McCarthy, John D.

2011-01-01

Why do some social movement leaders work harder than others? And, how does gender affect the patterns we uncover? Utilizing historical case study evidence of local chapters in the emerging movement opposing drinking and driving we are able to develop and test theoretical expectations about predictors of weekly effort among MADD and RID leaders.…

Shift Work, Chronotype, and Melatonin Patterns among Female Hospital Employees on Day and Night Shifts.

PubMed

Leung, Michael; Tranmer, Joan; Hung, Eleanor; Korsiak, Jill; Day, Andrew G; Aronson, Kristan J

2016-05-01

Shift work-related carcinogenesis is hypothesized to be mediated by melatonin; however, few studies have considered the potential effect modification of this underlying pathway by chronotype or specific aspects of shift work such as the number of consecutive nights in a rotation. In this study, we examined melatonin patterns in relation to shift status, stratified by chronotype and number of consecutive night shifts, and cumulative lifetime exposure to shift work. Melatonin patterns of 261 female personnel (147 fixed-day and 114 on rotations, including nights) at Kingston General Hospital were analyzed using cosinor analysis. Urine samples were collected from all voids over a 48-hour specimen collection period for measurement of 6-sulfatoxymelatonin concentrations using the Buhlmann ELISA Kit. Chronotypes were assessed using mid-sleep time (MSF) derived from the Munich Chronotype Questionnaire (MCTQ). Sociodemographic, health, and occupational information were collected by questionnaire. Rotational shift nurses working nights had a lower mesor and an earlier time of peak melatonin production compared to day-only workers. More pronounced differences in mesor and acrophase were seen among later chronotypes, and shift workers working ≥3 consecutive nights. Among nurses, cumulative shift work was associated with a reduction in mesor. These results suggest that evening-types and/or shift workers working ≥3 consecutive nights are more susceptible to adverse light-at-night effects, whereas long-term shift work may also chronically reduce melatonin levels. Cumulative and current exposure to shift work, including nights, affects level and timing of melatonin production, which may be related to carcinogenesis and cancer risk. Cancer Epidemiol Biomarkers Prev; 25(5); 830-8. ©2016 AACR. ©2016 American Association for Cancer Research.

Zonal disintegration of rocks around underground workings. Part II. Rock fracture simulated in equivalent materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shemyakin, E.I.; Fisenko, G.L.; Kurlenya, M.V.

1987-05-01

For a detailed testing of the effects discovered in situ, analysis of the patterns and origination conditions of fractured rock zones inside the bed around workings, and ways explosions affect the surrounding rocks, a program and a method of study on models of equivalent materials have been developed. The method of simulation on two- and three-dimensional models involved building in a solid or fissured medium a tunnel of a circular or arched cross section. The tests were done for elongate adit-type workings. At the first stage, three models were tested with different working support systems: anchor supports, concrete-spray supports andmore » no supports. Zone formation is shown and described. Tests were continued on two groups of three-dimensional models to bring the model closer to in situ conditions. The presence of gaping cracks and heavily fractured zones deep in the interior of the bed with a quasicylindrical symmetry indicates that the common views concerning the stressed-strained state of rocks around underground workings are at variance with the actual patterns of deformation and destruction of rocks near the workings in deep horizons.« less

Online Activity Levels Are Related to Caffeine Dependency.

PubMed

Phillips, James G; Landhuis, C Erik; Shepherd, Daniel; Ogeil, Rowan P

2016-05-01

Online activity could serve in the future as behavioral markers of emotional states for computer systems (i.e., affective computing). Hence, this study considered relationships between self-reported stimulant use and online study patterns. Sixty-two undergraduate psychology students estimated their daily caffeine use, and this was related to study patterns as tracked by their use of a Learning Management System (Blackboard). Caffeine dependency was associated with less time spent online, lower rates of file access, and fewer online activities completed. Reduced breadth or depth of processing during work/study could be used as a behavioral marker of stimulant use.

Influences of Mood Variability, Negative Moods, and Depression on Adolescent Cigarette Smoking

PubMed Central

Weinstein, Sally M.; Mermelstein, Robin J.

2013-01-01

Understanding the emotional risk factors for cigarette smoking in adolescence can greatly inform prevention efforts. The current study examined prospective relationships between three affective dimensions – negative mood variability, overall negative mood, and depression, affect-related smoking motives, and future smoking patterns among adolescents. The current study expands on prior research by using real-time methods to assess mood and by focusing on a key developmental transition in smoking behavior: the progression from experimentation or low level, infrequent use to higher use. Ninth and 10th grade students (N = 461; 55% girls) provided data on cigarette use at a baseline and follow-up 15-month wave, and also provided ecological momentary assessments of negative moods via palmtop computers for one week at each wave. Negative mood was examined via the means of negative mood reports at each wave, and mood variability was examined via the intraindividual standard deviations of negative mood reports at each wave. Depressive symptoms and smoking motives were also assessed. Findings supported a complex self-medication model of smoking escalation in adolescence whereby mood-smoking relationships differed by affect dimension and gender. For girls, greater negative mood variability at baseline significantly predicted rapid escalation in smoking over time, whereas depressive symptoms and overall negative mood were unrelated to girls’ smoking patterns. In contrast, overall negative mood significantly predicted boys’ smoking escalation among those with affect-related motives for smoking. Results thus suggest that inconsistent mood-smoking relations in past work may be driven by the complex interrelationships among affect vulnerabilities, gender, and smoking patterns. PMID:23438244

Dynamic Segmentation Of Behavior Patterns Based On Quantity Value Movement Using Fuzzy Subtractive Clustering Method

NASA Astrophysics Data System (ADS)

Sangadji, Iriansyah; Arvio, Yozika; Indrianto

2018-03-01

to understand by analyzing the pattern of changes in value movements that can dynamically vary over a given period with relative accuracy, an equipment is required based on the utilization of technical working principles or specific analytical method. This will affect the level of validity of the output that will occur from this system. Subtractive clustering is based on the density (potential) size of data points in a space (variable). The basic concept of subtractive clustering is to determine the regions in a variable that has high potential for the surrounding points. In this paper result is segmentation of behavior pattern based on quantity value movement. It shows the number of clusters is formed and that has many members.

"It's Different Now:" How Exit Exams Are Affecting Teaching and Learning in Jackson and Austin

ERIC Educational Resources Information Center

Zabala, Dalia; Minnici, Angela; Kober, Nancy, Ed.

2007-01-01

Since much of the previous research on exit exams, including CEP's own work, has looked at national patterns of implementation and passing rates, this study aimed to benefit policy and practice by focusing on the local level. Specifically, case studies were conducted in Jackson, MS and Austin, TX that examined how classroom instruction and other…

Economic and Technology Forecasts for the 80's: Implications for Careers. Proceedings of the Patterns Conference (Rochester Institute of Technology, May 1979).

ERIC Educational Resources Information Center

Nystrom, Dennis; And Others

Selected technological and research areas that may affect emerging careers and work expectations were discussed in the five seminar presentations contained in this proceedings. In the introductory section, Dennis Nystrom outlines the goals of the conference and suggests possible implications. Sar Levitan, in the keynote address, examines the…

Risk factors for alcoholism in the Oklahoma Family Health Patterns project: impact of early life adversity and family history on affect regulation and personality.

PubMed

Sorocco, Kristen H; Carnes, Nathan C; Cohoon, Andrew J; Vincent, Andrea S; Lovallo, William R

2015-05-01

This study examined the impact of early lifetime adversity (ELA) on affect regulation and personality in persons with family history (FH+) and without (FH-) a family history of alcoholism. We examined the impact of early life adversity in healthy young adults, 18-30 years of age enrolled in a long-term study on risk for alcohol and other substance abuse. ELA was assessed by a composite score of low socioeconomic status and personal experience of physical or sexual abuse and/or separation from parents before age 16, resulting in a score of 0, 1-2, or >3 adverse events. Unstable affect regulation and personality variables were obtained via self-report measures. Higher ELA scores were seen in FH+ (χ(2)=109.2, p<0.0001) and in women (χ(2)=17.82, p=0.0019). Although higher ELA predicted less emotional stability and more behavioral undercontrol, further analysis including both FH and ELA showed that FH+ persons are prone to poor affect regulation, negative moods, and have risky drinking and drug abuse tendencies independent of ELA level. ELA predicts reduced stress reactivity and poorer cognitive control over impulsive behaviors as shown elsewhere. The present work shows that FH+ have poor mood regulation and antisocial characteristics. The greater prevalence of ELA in FH+ persons indicates that life experience and FH+ work in tandem to result in risky patterns of alcohol and drug experimentation to elevate risk for alcoholism. Further studies of genetic and environmental contributions to alcoholism are called for. Published by Elsevier Ireland Ltd.

Arousal regulation and affective adaptation to human responsiveness by a robot that explores and learns a novel environment.

PubMed

Hiolle, Antoine; Lewis, Matthew; Cañamero, Lola

2014-01-01

In the context of our work in developmental robotics regarding robot-human caregiver interactions, in this paper we investigate how a "baby" robot that explores and learns novel environments can adapt its affective regulatory behavior of soliciting help from a "caregiver" to the preferences shown by the caregiver in terms of varying responsiveness. We build on two strands of previous work that assessed independently (a) the differences between two "idealized" robot profiles-a "needy" and an "independent" robot-in terms of their use of a caregiver as a means to regulate the "stress" (arousal) produced by the exploration and learning of a novel environment, and (b) the effects on the robot behaviors of two caregiving profiles varying in their responsiveness-"responsive" and "non-responsive"-to the regulatory requests of the robot. Going beyond previous work, in this paper we (a) assess the effects that the varying regulatory behavior of the two robot profiles has on the exploratory and learning patterns of the robots; (b) bring together the two strands previously investigated in isolation and take a step further by endowing the robot with the capability to adapt its regulatory behavior along the "needy" and "independent" axis as a function of the varying responsiveness of the caregiver; and (c) analyze the effects that the varying regulatory behavior has on the exploratory and learning patterns of the adaptive robot.

Nanomechanical control of optical field and quality factor in photonic crystal structures

NASA Astrophysics Data System (ADS)

Cotrufo, Michele; Midolo, Leonardo; Zobenica, Žarko; Petruzzella, Maurangelo; van Otten, Frank W. M.; Fiore, Andrea

2018-03-01

Actively controlling the properties of localized optical modes is crucial for cavity quantum electrodynamics experiments. While several methods to tune the optical frequency have been demonstrated, the possibility of controlling the shape of the modes has scarcely been investigated. Yet an active manipulation of the mode pattern would allow direct control of the mode volume and the quality factor and therefore of the radiative processes. In this work, we propose and demonstrate a nano-optoelectromechanical device in which a mechanical displacement affects the spatial pattern of the electromagnetic field. The device is based on a double-membrane photonic crystal waveguide which, upon bending, creates a spatial modulation of the effective refractive index, resulting in an effective potential well or antiwell for the optical modes. The change in the field pattern drastically affects the optical losses: large modulations of the quality factors and dissipative coupling rates larger than 1 GHz/nm are predicted by calculations and confirmed by experiments. This concept opens new avenues in solid-state cavity quantum electrodynamics in which the field, instead of the frequency, is coupled to the mechanical motion.

An In situ Analysis of the Dissolution Characteristics of Half Pitch Line and Space Extreme Ultraviolet Lithography Resist Patterns

NASA Astrophysics Data System (ADS)

Santillan, Julius Joseph; Itani, Toshiro

2013-06-01

The characterization of the resist dissolution is one fundamental area of research that has been continuously investigated. This paper focuses on the preliminary work on the application the high speed atomic force microscope (HS-AFM) for the in situ dissolution analysis half-pitch (hp) lines and spaces (L/S) at standard developer concentration. In earlier works, this has been difficult but through extensive optimization and the use of carbon nano fiber-tipped cantilevers, the dissolution characterization of a 32 nm hp L/S pattern at 0.26 N aqueous tetramethylammonium hydroxide developer (standard developer concentration) was successfully achieved. Based on the results obtained using the EIDEC standard resist (ESR1) it was found that regardless of analysis condition such as resist pattern configuration (isolated or L/S pattern) and developer concentration (diluted or standard), similar dissolution characteristics in the form of resist swelling of exposed areas was observed. Moreover, further investigations using other types of model resist polymer platforms such as poly(hydroxystyrene) (PHS)-based and hybrid (PHS-methacryl)-based model resists have confirmed that dissolution behavior is not affected by the analysis conditions applied.

Family Caregivers' Patterns of Positive and Negative Affect

ERIC Educational Resources Information Center

Robertson, Suzanne M.; Zarit, Steven H.; Duncan, Larissa G.; Rovine, Michael J.; Femia, Elia E.

2007-01-01

Stressful and positive family caregiving experiences were examined as predictors of caregivers' patterns of positive and negative affect in a sample of families providing care for a relative with dementia (N = 234). Four affect pattern groups were identified: (a) Well Adjusted (i.e., high positive affect, low negative affect); (b) Ambiguous (i.e.,…

Income, productivity, and satisfaction of breast surgeons.

PubMed

Bendorf, David C; Helmer, Stephen D; Osland, Jacqueline S; Tenofsky, Patty L

2010-03-01

The purpose of this study was to assess how the practice patterns of breast surgeons affect their income and job satisfaction. A 19-question survey regarding practice patterns and income and job satisfaction was mailed to all active US members of the American Society of Breast Surgeons. There were 772 responses. An increasing percentage of breast care was associated with lower incomes (P=.0001) and similar income satisfaction (P=.4517) but higher job satisfaction (P=.0001). The increasing proportion of breast care was also associated with fewer hours worked per week (P=.0001). Although incomes were lower in surgeons with a higher proportion of their practice in breast care, income satisfaction was not affected. Although cause and effect relationships between income and breast surgery are difficult to establish, several trends do emerge. Most significantly, we found that dedicated breast surgeons have higher job satisfaction ratings and similar income satisfaction despite lower incomes. Copyright (c) 2010 Elsevier Inc. All rights reserved.

The synergic role of sociotechnical and personal characteristics on work injuries in mines.

PubMed

Paul, P S; Maiti, J

2008-05-01

Occupational injuries in mines are attributed to many factors. In this study, an attempt was made to identify the various factors related to work injuries in mines and to estimate their effects on work injuries to mine workers. An accident path model was developed to estimate the pattern and strength of relationships amongst the personal and sociotechnical variables in accident/injury occurrences. The input data for the model were the correlation matrix of 18 variables, which were collected from the case study mines. The case study results showed that there are sequential interactions amongst the sociotechnical and personal factors leading to accidents/injuries in mines. Amongst the latent endogenous constructs, job dissatisfaction and safe work behaviour show a significant positive and negative direct relationship with work injury, respectively. However, the construct safety environment has a significant negative indirect relationship with work injury. The safety environment is negatively affected by work hazards and positively affected by social support. The safety environment also shows a significant negative relationship with job stress and job dissatisfaction. However, negative personality has no significant direct or indirect effect on work injury, but it has a significant negative relationship with safe work behaviour. The endogenous construct negative personality is positively influenced by job stress and negatively influenced by social support.

Prevalence of Suicidal Ideation and Its Association with Positive Affect in Working Women: A Day Reconstruction Study

PubMed Central

Tian, Lili; Yang, Ying; Yang, Huijing; Huebner, E. Scott

2017-01-01

The suicide rate for females in China is the second highest worldwide, and China is the only country in the world in which the rate of suicides is higher for women than men. Affective instability has been shown to be a strong predictor of suicidal ideation, particularly among women. However, prior research has mainly focused on the impact of women's negative affect on suicidal ideation, ignoring the influence of positive affect on suicidal ideation. Studies have revealed that hopelessness, which is 1.3 times more important than depression for explaining suicidal ideation, is driven more by low levels of positive affect than by high levels of negative affect. Although positive affect has also been found to be related to suicidal ideation, and it demonstrates independent, beneficial effects on mental health, much remains to be learned about the association between positive affective instability and suicidal ideation. Therefore, we investigated the prevalence of suicidal ideation among Chinese working women and explored the differences between working women with and without suicidal ideation in the intensity and daily variability of positive affect. A total of 222 young working women of ages 22–36 years (M = 27.64, SD = 3.73) were recruited from a free weekend psychology lecture. The women subsequently completed a daily diary Day Reconstruction Method (DRM) as well as a suicidal ideation questionnaire. We used hierarchical linear modeling (HLM) to analyze the data, and the results showed that: (1) 10.81% of participates reported suicidal ideation, the intensity of positive affect (happiness, warmth/friendliness, interest and relaxation/calmness) was significantly lower for women with suicidal ideation compared to women without suicidal ideation; (2) differing diurnal patterns of positive emotions were observed between women with and without suicidal ideation; women with suicidal ideation demonstrated a significantly lower trend of growth and a higher volatility in happiness, warmth/friendliness, relaxation/calmness. Given that lower intensity of positive affect and greater affective instability significantly predicted suicidal ideation in Chinese women, researchers should pay more attention to the role of positive affect in female suicide prevention research and intervention efforts in the future. PMID:28377731

Prevalence of Suicidal Ideation and Its Association with Positive Affect in Working Women: A Day Reconstruction Study.

PubMed

Tian, Lili; Yang, Ying; Yang, Huijing; Huebner, E Scott

2017-01-01

The suicide rate for females in China is the second highest worldwide, and China is the only country in the world in which the rate of suicides is higher for women than men. Affective instability has been shown to be a strong predictor of suicidal ideation, particularly among women. However, prior research has mainly focused on the impact of women's negative affect on suicidal ideation, ignoring the influence of positive affect on suicidal ideation. Studies have revealed that hopelessness, which is 1.3 times more important than depression for explaining suicidal ideation, is driven more by low levels of positive affect than by high levels of negative affect. Although positive affect has also been found to be related to suicidal ideation, and it demonstrates independent, beneficial effects on mental health, much remains to be learned about the association between positive affective instability and suicidal ideation. Therefore, we investigated the prevalence of suicidal ideation among Chinese working women and explored the differences between working women with and without suicidal ideation in the intensity and daily variability of positive affect. A total of 222 young working women of ages 22-36 years ( M = 27.64, SD = 3.73) were recruited from a free weekend psychology lecture. The women subsequently completed a daily diary Day Reconstruction Method (DRM) as well as a suicidal ideation questionnaire. We used hierarchical linear modeling (HLM) to analyze the data, and the results showed that: (1) 10.81% of participates reported suicidal ideation, the intensity of positive affect (happiness, warmth/friendliness, interest and relaxation/calmness) was significantly lower for women with suicidal ideation compared to women without suicidal ideation; (2) differing diurnal patterns of positive emotions were observed between women with and without suicidal ideation; women with suicidal ideation demonstrated a significantly lower trend of growth and a higher volatility in happiness, warmth/friendliness, relaxation/calmness. Given that lower intensity of positive affect and greater affective instability significantly predicted suicidal ideation in Chinese women, researchers should pay more attention to the role of positive affect in female suicide prevention research and intervention efforts in the future.

Occupational class and the changing patterns of hospitalization for affective and neurotic disorders: a nationwide register-based study of the Finnish working-age population, 1976-2010.

PubMed

Varje, Pekka; Kouvonen, Anne; Kokkinen, Lauri; Koskinen, Aki; Väänänen, Ari

2018-02-01

This study aimed to examine the long-term changes and socioeconomic disparities in hospitalization for affective and neurotic disorders among the Finnish working-age population from 1976 to 2010. Register-based study, consisting of a 5-year follow-up of 3,223,624 Finnish working-age (18-64-year old) individuals in seven consecutive cohorts. We calculated the hazard ratios of psychiatric hospitalization for different occupational classes using Cox regression models. The risk of hospitalization for affective and neurotic disorders increased in all occupational classes after the economic recession in the 1990s, and then decreased in the 2000s. Before the 2000s, the risk was the highest among manual workers. In the 2000s the disparities between upper-level non-manual employees and other occupational classes increased. Hospitalization rates remained high among female manual workers and non-manual lower-level employees. This study revealed important similarities and differences between occupational classes in terms of long-term changes in hospitalization for affective and neurotic disorders. The results suggest that the labor market changes and healthcare reforms during the 1990s and 2000s in Finland have been more beneficial for higher than for lower occupational classes.

On the influence of surface patterning on tissue self-assembly and mechanics.

PubMed

Coppola, Valerio; Ventre, Maurizio; Natale, Carlo F; Rescigno, Francesca; Netti, Paolo A

2018-04-28

Extracellular matrix assembly and composition influence the biological and mechanical functions of tissues. Developing strategies to control the spatial arrangement of cells and matrix is of central importance for tissue engineering-related approaches relying on self-assembling and scaffoldless processes. Literature reports demonstrated that signals patterned on material surfaces are able to control cell positioning and matrix orientation. However, the mechanisms underlying the interactions between material signals and the structure of the de novo synthesized matrix are far from being thoroughly understood. In this work, we investigated the ordering effect provided by nanoscale topographic patterns on the assembly of tissue sheets grown in vitro. We stimulated MC3T3-E1 preosteoblasts to produce and assemble a collagen-rich matrix on substrates displaying patterns with long- or short-range order. Then, we investigated microstructural features and mechanical properties of the tissue in uniaxial tension. Our results demonstrate that patterned material surfaces are able to control the initial organization of cells in close contact to the surface; then cell-generated contractile forces profoundly remodel tissue structure towards mechanically stable spatial patterns. Such a remodelling effect acts both locally, as it affects cell and nuclear shape and globally, by affecting the gross mechanical response of the tissue. Such an aspect of dynamic interplay between cells and the surrounding matrix must be taken into account when designing material platform for the in vitro generation of tissue with specific microstructural assemblies. Copyright © 2018 John Wiley & Sons, Ltd.

Midtarsal locking, the windlass mechanism, and running strike pattern: A kinematic and kinetic assessment.

PubMed

Bruening, Dustin A; Pohl, Michael B; Takahashi, Kota Z; Barrios, Joaquin A

2018-05-17

Changes in running strike pattern affect ankle and knee mechanics, but little is known about the influence of strike pattern on the joints distal to the ankle. The purpose of this study was to explore the effects of forefoot strike (FFS) and rearfoot strike (RFS) running patterns on foot kinematics and kinetics, from the perspectives of the midtarsal locking theory and the windlass mechanism. Per the midtarsal locking theory, we hypothesized that the ankle would be more inverted in early stance when using a FFS, resulting in decreased midtarsal joint excursions and increased dynamic stiffness. Associated with a more engaged windlass mechanism, we hypothesized that a FFS would elicit increased metatarsophalangeal joint excursions and negative work in late stance. Eighteen healthy female runners ran overground with both FFS and RFS patterns. Instrumented motion capture and a validated multi-segment foot model were used to analyze midtarsal and metatarsophalangeal joint kinematics and kinetics. During early stance in FFS the ankle was more inverted, with concurrently decreased midtarsal eversion (p < 0.001) and abduction excursions (p = 0.003) but increased dorsiflexion excursion (p = 0.005). Dynamic midtarsal stiffness did not differ (p = 0.761). During late stance in FFS, metatarsophalangeal extension was increased (p = 0.009), with concurrently increased negative work (p < 0.001). In addition, there was simultaneously increased midtarsal positive work (p < 0.001), suggesting enhanced power transfer in FFS. Clear evidence for the presence of midtarsal locking was not observed in either strike pattern during running. However, the windlass mechanism appeared to be engaged to a greater extent during FFS. Copyright © 2018 Elsevier Ltd. All rights reserved.

Implications of current resident work-hour guidelines on the future practice of surgery in Canada.

PubMed

Maruscak, Adam A; VanderBeek, Laura; Ott, Michael C; Kelly, Stephen; Forbes, Thomas L

2012-01-01

Work-hour restrictions have had a profound impact on surgical training. However, little is known of how work-hour restrictions may affect the future practice patterns of current surgical residents. The purpose of this study is to compare the anticipated career practice patterns of surgical residents who are training within an environment of work-hour restrictions with the current practice of faculty surgeons. An electronic survey was sent to all surgery residents and faculty at 2 Canadian university-affiliated medical centers. The survey consisted of questions regarding expected (residents) or current (faculty) practice patterns. A total of 149 residents and 125 faculty members completed the survey (50.3% and 52.3% response rates, respectively). A greater proportion of males were in the faculty cohort than in the resident group (77.6% vs 62.4%, p = 0.0003). More faculty than residents believed that work-hour restrictions have a negative impact on both residency education (40.8% vs 20.8%, p = 0.008) and preparation for a surgical career (56.8% vs 19.5%, p < 0.0001). Compared with current faculty, residents plan to take less call (p < 0.0003), work fewer days of the week (p < 0.0001), are more likely to limit their duty hours on postcall days (p = 0.009), and take parental leave (p = 0.02) once in practice. Male and female residents differed somewhat in their responses in that more female residents plan to limit their postcall duty hours (55.4% vs 36.5%, p = 0.009) and to take a parental leave (51.8% vs 16.1%, p < 0.0001) compared with their male resident colleagues. Current surgical residents expect to adopt components of resident work-hour guidelines into their surgical practices after completing their residency. These practice patterns will have surgical workforce implications and might require larger surgical groups and reconsideration of resource allocation. Copyright © 2012 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

Lattice-patterned LC-polymer composites containing various nanoparticles as additives

PubMed Central

2012-01-01

In this study, we show the effect of various nanoparticle additives on phase separation behavior of a lattice-patterned liquid crystal [LC]-polymer composite system and on interfacial properties between the LC and polymer. Lattice-patterned LC-polymer composites were fabricated by exposing to UV light a mixture of a prepolymer, an LC, and SiO2 nanoparticles positioned under a patterned photomask. This resulted in the formation of an LC and prepolymer region through phase separation. We found that the incorporation of SiO2 nanoparticles significantly affected the electro-optical properties of the lattice-patterned LC-polymer composites. This effect is a fundamental characteristic of flexible displays. The electro-optical properties depend on the size and surface functional groups of the SiO2 nanoparticles. Compared with untreated pristine SiO2 nanoparticles, which adversely affect the performance of LC molecules surrounded by polymer walls, SiO2 nanoparticles with surface functional groups were found to improve the electro-optical properties of the lattice-patterned LC-polymer composites by increasing the quantity of SiO2 nanoparticles. The surface functional groups of the SiO2 nanoparticles were closely related to the distribution of SiO2 nanoparticles in the LC-polymer composites, and they influenced the electro-optical properties of the LC molecules. It is clear from our work that the introduction of nanoparticles into a lattice-patterned LC-polymer composite provides a method for controlling and improving the composite's electro-optical properties. This technique can be used to produce flexible substrates for various flexible electronic devices. PMID:22222011

Rainfall Patterns Analysis over Ampangan Muda, Kedah from 2007 - 2016

NASA Astrophysics Data System (ADS)

Chooi Tan, Kok

2018-04-01

The scientific knowledge about climate change and climate variability over Malaysia pertaining to the extreme water-related disaster such as drought and flood. A deficit or increment in precipitation occurred over the past century becomes a useful tool to understand the climate change in Malaysia. The purpose of this work is to examine the rainfall patterns over Ampangan Muda, Kedah. Daily rainfall data is acquired from Malaysian Meteorological Department to analyse the temporal and trends of the monthly and annual rainfall over the study area from 2007 to 2016. The obtained results show that the temporal and patterns of the rainfall over Ampangan Muda, Kedah is largely affected by the regional phenomena such as monsoon, El Niño Southern Oscillation (ENSO), and the Madden-Julian Oscillation. In addition, backward trajectories analysis is also used to identify the patterns for long-range of synoptic circulation over the region.

An equilibrium-point model of electromyographic patterns during single-joint movements based on experimentally reconstructed control signals.

PubMed

Latash, M L; Goodman, S R

1994-01-01

The purpose of this work has been to develop a model of electromyographic (EMG) patterns during single-joint movements based on a version of the equilibrium-point hypothesis, a method for experimental reconstruction of the joint compliant characteristics, the dual-strategy hypothesis, and a kinematic model of movement trajectory. EMG patterns are considered emergent properties of hypothetical control patterns that are equally affected by the control signals and peripheral feedback reflecting actual movement trajectory. A computer model generated the EMG patterns based on simulated movement kinematics and hypothetical control signals derived from the reconstructed joint compliant characteristics. The model predictions have been compared to published recordings of movement kinematics and EMG patterns in a variety of movement conditions, including movements over different distances, at different speeds, against different-known inertial loads, and in conditions of possible unexpected decrease in the inertial load. Changes in task parameters within the model led to simulated EMG patterns qualitatively similar to the experimentally recorded EMG patterns. The model's predictive power compares it favourably to the existing models of the EMG patterns. Copyright © 1994. Published by Elsevier Ltd.

Implications for U.S. trade and nonindigenous species risk resulting from increased economic integration of the Asia-Pacific Region

Treesearch

Amanda M. Countryman; Travis Warziniack; Erin Grey

2018-01-01

This work investigates how potential changes in trade patterns resulting from increased economic integration in the Asia-Pacific region may affect the risk for nonindigenous species spread to the United States. We construct an invasion risk index utilizing the results from a global economic modeling framework in tandem with data for climate similarities between trade...

Aspects of the Two Language System and Three Language Problem in the Changing Society of Hong Kong.

ERIC Educational Resources Information Center

Tsou, Benjamin K.

1996-01-01

Presents details of the language shifts among the various sections of the Chinese-speaking population in Hong Kong and analyzes patterns of allegiance. Notes that complex social, economic, and political pressures will affect future language in Hong Kong and that, within the domains of family, work, and others, the use of Modern Standard Chinese is…

Can sleep quality and burnout affect the job performance of shift-work nurses? A hospital cross-sectional study.

PubMed

Giorgi, Fabio; Mattei, Antonella; Notarnicola, Ippolito; Petrucci, Cristina; Lancia, Loreto

2018-03-01

The aim of this study was to investigate any possible relationship between sleep disorders, burnout and job performance in a shift-work population of nurses. Sleep disorders and burnout can affect the job performance of nurses in terms of efficiency, productivity, task execution speed and supervision, which can be compromised when work shifts are organized on a 24-hour schedule and when the shift itself is irregular. A cross-sectional observational study was conducted from August 2014 - January 2015 on a sample of 315 shift-work nurses across 39 wards in seven central Italian hospitals. The Pittsburgh Sleep Quality Index was used to detect the presence of sleep disorders, the Copenhagen Burnout Inventory was used to detect the presence of any possible type of burnout and the Job Performance Scale was used to measure job performance. Data analysis was mainly based on a multivariate logistic regression to identify variables significantly associated with investigated outcomes. On shift-work nurses' sleep quality and burnout correlated positively. The female gender and personal burnout were significantly associated with impaired sleep quality, while working in the psychiatric setting, working a long cycle shift pattern and experiencing daytime dysfunction were significantly associated with burnout. A significant negative association between patient-related burnout and job performance was observed. Specific characteristics of shift-work nurses can directly affect sleep quality and burnout and indirectly job performance. This evidence offers healthcare administrators opportunities to intervene with measures to promote nurse's health, well-being and safety. © 2017 John Wiley & Sons Ltd.

The transition to parenthood and well-being: the impact of partner status and work hour transitions.

PubMed

Keizer, Renske; Dykstra, Pearl A; Poortman, Anne-Rigt

2010-08-01

Using data from the first two waves of the Netherlands Kinship Panel Study for 338 women and 262 men, we examine the consequences of making the transition to parenthood for life satisfaction, loneliness, positive affect, negative affect, and partnership satisfaction. We extend previous work by taking transitions in partner status and work hours into account. Results show a moderate impact of becoming a parent on well-being. In so far as effects of making the transition to parenthood emerge, they are attributable to changes in partner status and work hours. First, the decrease in negative affect upon making the transition to motherhood is attributable to the group of women who increase their working hours. Second, the detrimental impact of making the transition to motherhood on partnership satisfaction is attributable to the group of new mothers who quit their job. Third, the detrimental impact of making the transition to fatherhood on loneliness is attributable to the group of new fathers who become married. There is one exception to this pattern of partner status and work hours as mechanisms for changes in well-being. Men who become fathers remain less satisfied with their partnership, even when transitions in partner status and work hours have been taken into account. In the discussion-section, we consider the possible underestimation of negative effects because of the focus on the continuously partnered. We also reflect on our results in the light of the high incidence of part-time work in the Netherlands and Dutch policies aimed at supporting new parents.

The effect of process parameters on Twin Wire Arc spray pattern shape

DOE PAGES

Hall, Aaron Christopher; McCloskey, James Francis; Horner, Allison Lynne

2015-04-20

A design of experiments approach was used to describe process parameter—spray pattern relationships in the Twin Wire Arc process using zinc feed stock in a TAFA 8835 (Praxair, Concord, NH, USA) spray torch. Specifically, the effects of arc current, primary atomizing gas pressure, and secondary atomizing gas pressure on spray pattern size, spray pattern flatness, spray pattern eccentricity, and coating deposition rate were investigated. Process relationships were investigated with the intent of maximizing or minimizing each coating property. It was determined that spray pattern area was most affected by primary gas pressure and secondary gas pressure. Pattern eccentricity was mostmore » affected by secondary gas pressure. Pattern flatness was most affected by primary gas pressure. Lastly, coating deposition rate was most affected by arc current.« less

The effect of process parameters on Twin Wire Arc spray pattern shape

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hall, Aaron Christopher; McCloskey, James Francis; Horner, Allison Lynne

A design of experiments approach was used to describe process parameter—spray pattern relationships in the Twin Wire Arc process using zinc feed stock in a TAFA 8835 (Praxair, Concord, NH, USA) spray torch. Specifically, the effects of arc current, primary atomizing gas pressure, and secondary atomizing gas pressure on spray pattern size, spray pattern flatness, spray pattern eccentricity, and coating deposition rate were investigated. Process relationships were investigated with the intent of maximizing or minimizing each coating property. It was determined that spray pattern area was most affected by primary gas pressure and secondary gas pressure. Pattern eccentricity was mostmore » affected by secondary gas pressure. Pattern flatness was most affected by primary gas pressure. Lastly, coating deposition rate was most affected by arc current.« less

Laser Surface Microstructuring of Biocompatible Materials Using a Microlens Array and the Talbot Effect: Evaluation of the Cell Adhesion.

PubMed

Aymerich, María; Nieto, Daniel; Álvarez, Ezequiel; Flores-Arias, María T

2017-02-22

A laser based technique for microstructuring titanium and tantalum substrates using the Talbot effect and an array of microlenses is presented. By using this hybrid technique; we are able to generate different patterns and geometries on the top surfaces of the biomaterials. The Talbot effect allows us to rapidly make microstructuring, solving the common problems of using microlenses for multipatterning; where the material expelled during the ablation of biomaterials damages the microlens. The Talbot effect permits us to increase the working distance and reduce the period of the patterns. We also demonstrate that the geometries and patterns act as anchor points for cells; affecting the cell adhesion to the metallic substrates and guiding how they spread over the material.

Capturing Physiology of Emotion along Facial Muscles: A Method of Distinguishing Feigned from Involuntary Expressions

NASA Astrophysics Data System (ADS)

Khan, Masood Mehmood; Ward, Robert D.; Ingleby, Michael

The ability to distinguish feigned from involuntary expressions of emotions could help in the investigation and treatment of neuropsychiatric and affective disorders and in the detection of malingering. This work investigates differences in emotion-specific patterns of thermal variations along the major facial muscles. Using experimental data extracted from 156 images, we attempted to classify patterns of emotion-specific thermal variations into neutral, and voluntary and involuntary expressions of positive and negative emotive states. Initial results suggest (i) each facial muscle exhibits a unique thermal response to various emotive states; (ii) the pattern of thermal variances along the facial muscles may assist in classifying voluntary and involuntary facial expressions; and (iii) facial skin temperature measurements along the major facial muscles may be used in automated emotion assessment.

Laser Surface Microstructuring of Biocompatible Materials Using a Microlens Array and the Talbot Effect: Evaluation of the Cell Adhesion

PubMed Central

Aymerich, María; Nieto, Daniel; Álvarez, Ezequiel; Flores-Arias, María T.

2017-01-01

A laser based technique for microstructuring titanium and tantalum substrates using the Talbot effect and an array of microlenses is presented. By using this hybrid technique; we are able to generate different patterns and geometries on the top surfaces of the biomaterials. The Talbot effect allows us to rapidly make microstructuring, solving the common problems of using microlenses for multipatterning; where the material expelled during the ablation of biomaterials damages the microlens. The Talbot effect permits us to increase the working distance and reduce the period of the patterns. We also demonstrate that the geometries and patterns act as anchor points for cells; affecting the cell adhesion to the metallic substrates and guiding how they spread over the material. PMID:28772574

Type 1 Diabetes Modifies Brain Activation in Young Patients While Performing Visuospatial Working Memory Tasks

PubMed Central

González-Garrido, Andrés A.; Gudayol-Ferré, Esteban; Guàrdia-Olmos, Joan

2015-01-01

In recent years, increasing attention has been paid to the effects of Type 1 Diabetes (T1D) on cognitive functions. T1D onset usually occurs during childhood, so it is possible that the brain could be affected during neurodevelopment. We selected young patients of normal intelligence with T1D onset during neurodevelopment, no complications from diabetes, and adequate glycemic control. The purpose of this study was to compare the neural BOLD activation pattern in a group of patients with T1D versus healthy control subjects while performing a visuospatial working memory task. Sixteen patients and 16 matched healthy control subjects participated. There was no significant statistical difference in behavioral performance between the groups, but, in accordance with our hypothesis, results showed distinct brain activation patterns. Control subjects presented the expected activations related to the task, whereas the patients had greater activation in the prefrontal inferior cortex, basal ganglia, posterior cerebellum, and substantia nigra. These different patterns could be due to compensation mechanisms that allow them to maintain a behavioral performance similar to that of control subjects. PMID:26266268

Identifying ADHD children using hemodynamic responses during a working memory task measured by functional near-infrared spectroscopy.

PubMed

Gu, Yue; Miao, Shuo; Han, Junxia; Liang, Zhenhu; Ouyang, Gaoxiang; Yang, Jian; Li, Xiaoli

2018-06-01

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder affecting children and adults. Previous studies found that functional near-infrared spectroscopy (fNIRS) can reveal significant group differences in several brain regions between ADHD children and healthy controls during working memory tasks. This study aimed to use fNIRS activation patterns to identify ADHD children from healthy controls. FNIRS signals from 25 ADHD children and 25 healthy controls performing the n-back task were recorded; then, multivariate pattern analysis was used to discriminate ADHD individuals from healthy controls, and classification performance was evaluated for significance by the permutation test. The results showed that 86.0% ([Formula: see text]) of participants can be correctly classified in leave-one-out cross-validation. The most discriminative brain regions included the bilateral dorsolateral prefrontal cortex, inferior medial prefrontal cortex, right posterior prefrontal cortex, and right temporal cortex. This study demonstrated that, in a small sample, multivariate pattern analysis can effectively identify ADHD children from healthy controls based on fNIRS signals, which argues for the potential utility of fNIRS in future assessments.

Fabrication of volcano-shaped nano-patterned sapphire substrates using colloidal self-assembly and wet chemical etching.

PubMed

Geng, Chong; Zheng, Lu; Fang, Huajing; Yan, Qingfeng; Wei, Tongbo; Hao, Zhibiao; Wang, Xiaoqing; Shen, Dezhong

2013-08-23

Patterned sapphire substrates (PSS) have been widely used to enhance the light output power in GaN-based light emitting diodes. The shape and feature size of the pattern in a PSS affect its enhancement efficiency to a great degree. In this work we demonstrate the nanoscale fabrication of volcano-shaped PSS using a wet chemical etching approach in combination with a colloidal monolayer templating strategy. Detailed analysis by scanning electron microscopy reveals that the unique pattern shape is a result of the different corrosion-resistant abilities of silica masks of different effective heights during wet chemical etching. The formation of silica etching masks of different effective heights has been ascribed to the silica precursor solution in the interstice of the colloidal monolayer template being distributed unevenly after infiltration. In the subsequent wet chemical etching process, the active reaction sites altered as etching duration was prolonged, resulting in the formation of volcano-shaped nano-patterned sapphire substrates.

Impact of long farm working hours on child safety practices in agricultural settings.

PubMed

Marlenga, Barbara; Pahwa, Punam; Hagel, Louise; Dosman, James; Pickett, William; Brison, Robert J; Crowe, Trever; Koehncke, Niels; Snodgrass, Phyllis; Day, Lesley; Voaklander, Donald

2010-01-01

To characterize working hours of adult farm owner-operators and their spouses by season, and to examine associations between working hours and farm safety practices affecting children. We conducted a secondary analysis of cross-sectional survey data collected as part of an existing study of injury and its determinants. Owner-operators reported a median of 60 to 70 hours of farm work per week during warm weather months, with declines in hours over the winter. Spouses reported similar seasonal patterns, although their median reported hours were much lower. Longer farm working hours by owner-operators were marginally associated with increased exposure of teenagers to farm work hazards. Exposures of young children to worksite hazards rose in association with longer farm working hours by spouses. Exposures of children to farm worksite hazards and demands may be consequences of adult long working hours. © 2010 National Rural Health Association.

Occupational and environmental reproductive hazards education and resources for communities of color.

PubMed Central

Dula, A; Kurtz, S; Samper, M L

1993-01-01

Little research has been published on the occupational and environmental hazards affecting people of color. Even less is known about the hazards that affect women of color. Although women of color have always been aggressive participants in the work force, their labor activity has increased dramatically over the last decade. Current job placement patterns suggest that women of color are concentrated in the lowest-paying and most hazardous jobs. In this paper, we specifically focus on occupational and environmental reproductive health concerns. We write with the understanding that reproductive hazards can affect pregnant women, nonpregnant women, and men, as well as the health and development of young children. Emphasis is placed primarily on African American women, because information on Hispanic, Native American, and Asian women is very limited. We discuss the participation of women of color in the labor force, using the U.S. Department of Labor categories. We review specific occupational hazards associated with each category of work and briefly discuss environmental hazards, noting that communities of color are at a disproportionate risk of exposure. Finally, we present the consensus report of the Community Education Working Group from the Woods Hole Conference on Occupational and Environmental Reproductive Hazards. PMID:8243389

Recent variations in seasonality of temperature and precipitation in Canada, 1976-95

NASA Astrophysics Data System (ADS)

Whitfield, Paul H.; Bodtker, Karin; Cannon, Alex J.

2002-11-01

A previously reported analysis of rehabilitated monthly temperature and precipitation time series for several hundred stations across Canada showed generally spatially coherent patterns of variation between two decades (1976-85 and 1986-95). The present work expands that analysis to finer time scales and a greater number of stations. We demonstrate how the finer temporal resolution, at 5 day or 11 day intervals, increases the separation between clusters of recent variations in seasonal patterns of temperature and precipitation. We also expand the analysis by increasing the number of stations from only rehabilitated monthly data sets to rehabilitated daily sets, then to approximately 1500 daily observation stations. This increases the spatial density of data and allows a finer spatial resolution of patterns between the two decades. We also examine the success of clustering partial records, i.e. sites where the data record is incomplete. The intent of this study was to be consistent with previous work and explore how greater temporal and spatial detail in the climate data affects the resolution of patterns of recent climate variations. The variations we report for temperature and precipitation are taking place at different temporal and spatial scales. Further, the spatial patterns are much broader than local climate regions and ecozones, indicating that the differences observed may be the result of variations in atmospheric circulation.

Genetic constraints on wing pattern variation in Lycaeides butterflies: A case study on mapping complex, multifaceted traits in structured populations.

PubMed

Lucas, Lauren K; Nice, Chris C; Gompert, Zachariah

2018-03-13

Patterns of phenotypic variation within and among species can be shaped and constrained by trait genetic architecture. This is particularly true for complex traits, such as butterfly wing patterns, that consist of multiple elements. Understanding the genetics of complex trait variation across species boundaries is difficult, as it necessitates mapping in structured populations and can involve many loci with small or variable phenotypic effects. Here, we investigate the genetic architecture of complex wing pattern variation in Lycaeides butterflies as a case study of mapping multivariate traits in wild populations that include multiple nominal species or groups. We identify conserved modules of integrated wing pattern elements within populations and species. We show that trait covariances within modules have a genetic basis and thus represent genetic constraints that can channel evolution. Consistent with this, we find evidence that evolutionary changes in wing patterns among populations and species occur in the directions of genetic covariances within these groups. Thus, we show that genetic constraints affect patterns of biological diversity (wing pattern) in Lycaeides, and we provide an analytical template for similar work in other systems. © 2018 John Wiley & Sons Ltd.

The genetic pattern of population threat and loss: a case study of butterflies.

PubMed

Schmitt, T; Hewitt, G M

2004-01-01

Recent decreases in biodiversity in Europe are commonly thought to be due to land use and climate change. However, the genetic diversity of populations is also seen as one essential factor for their fitness. Genetic diversity in species across the continent of Europe has been recognized as being in part a consequence of ice age isolation in southern refugia and postglacial colonization northwards, and these phylogeographical patterns may themselves affect the adaptability of populations. Recent work on butterfly species with different refugia, colonization paths and genetic structures allows this idea to be examined. The 'chalk-hill blue' pattern is one of decreasing genetic diversity from south to north, whereas the 'woodland ringlet' pattern shows greater genetic diversity in eastern than in western lineages. Comparison of population demographic trends in species with these biogeographical patterns reveals higher rates of decrease with lower genetic diversity. This indicates reduced adaptability due to genetic impoverishment as a result of glacial and postglacial range changes. Analysis of phylogeographical pattern may be a useful guide to interpreting demographic trends and in conservation planning.

Arousal regulation and affective adaptation to human responsiveness by a robot that explores and learns a novel environment

PubMed Central

Hiolle, Antoine; Lewis, Matthew; Cañamero, Lola

2014-01-01

In the context of our work in developmental robotics regarding robot–human caregiver interactions, in this paper we investigate how a “baby” robot that explores and learns novel environments can adapt its affective regulatory behavior of soliciting help from a “caregiver” to the preferences shown by the caregiver in terms of varying responsiveness. We build on two strands of previous work that assessed independently (a) the differences between two “idealized” robot profiles—a “needy” and an “independent” robot—in terms of their use of a caregiver as a means to regulate the “stress” (arousal) produced by the exploration and learning of a novel environment, and (b) the effects on the robot behaviors of two caregiving profiles varying in their responsiveness—“responsive” and “non-responsive”—to the regulatory requests of the robot. Going beyond previous work, in this paper we (a) assess the effects that the varying regulatory behavior of the two robot profiles has on the exploratory and learning patterns of the robots; (b) bring together the two strands previously investigated in isolation and take a step further by endowing the robot with the capability to adapt its regulatory behavior along the “needy” and “independent” axis as a function of the varying responsiveness of the caregiver; and (c) analyze the effects that the varying regulatory behavior has on the exploratory and learning patterns of the adaptive robot. PMID:24860492

How Work Organization Affects the Prevalence of WMSDs: A Case-control Study.

PubMed

Liu, Lu; Chen, Song Gen; Tang, Shi Chuan; Wang, Sheng; He, Li Hua; Guo, Ze Hua; Li, Jing Yun; Yu, Shan Fa; Wang, Zhong Xu

2015-09-01

In this study, we aimed at exploring the association between work-related musculoskeletal disorders (WMSDs) and work organization based on a case-control study. A total of 1938 workers who claimed to suffer from WMSDs were selected from Beijing, Henan, Hubei, and the Guangdong province. The control group consisted of 2009 workers employed in similar industries without severe disease or musculoskeletal discomforts. We used a modified version of the questionnaire developed by the NMQ and the DMQ to investigate individual and work-related factors. A total of 13 variables (P<0.1) were selected by the chi-square test and finally, 7 variables entered into the equation, with 6 variables reaching statistical significance (P<0.05). The odds ratios (OR) of 'work changing with season' and 'sufficient rest time' did not reach 1 (0.749 and 0.441, respectively). In addition, 'sufficient rest time' seemed to be the stronger protective factor according to its higher standardized coefficient. And 'repetitive work every minute', 'constantly repetitive work' (every day), 'shortage of site personnel', and 'often switching shifts with others' seemed to be the risk factors. Work organization may have comprehensive effects on the occurrence of WMSDs. This pattern of associations suggests that further investigation into the mechanism of how work organization affects the prevalence of WMSDs is required. Copyright © 2015 The Editorial Board of Biomedical and Environmental Sciences. Published by China CDC. All rights reserved.

Computational nanometrology of line-edge roughness: noise effects, cross-line correlations and the role of etch transfer

NASA Astrophysics Data System (ADS)

Constantoudis, Vassilios; Papavieros, George; Lorusso, Gian; Rutigliani, Vito; Van Roey, Frieda; Gogolides, Evangelos

2018-03-01

The aim of this paper is to investigate the role of etch transfer in two challenges of LER metrology raised by recent evolutions in lithography: the effects of SEM noise and the cross-line and edge correlations. The first comes from the ongoing scaling down of linewidths, which dictates SEM imaging with less scanning frames to reduce specimen damage and hence with more noise. During the last decade, it has been shown that image noise can be an important budget of the measured LER while systematically affects and alter the PSD curve of LER at high frequencies. A recent method for unbiased LER measurement is based on the systematic Fourier or correlation analysis to decompose the effects of noise from true LER (Fourier-Correlation filtering method). The success of the method depends on the PSD and HHCF curve. Previous experimental and model works have revealed that etch transfer affects the PSD of LER reducing its high frequency values. In this work, we estimate the noise contribution to the biased LER through PSD flat floor at high frequencies and relate it with the differences between the PSDs of lithography and etched LER. Based on this comparison, we propose an improvement of the PSD/HHCF-based method for noise-free LER measurement to include the missed high frequency real LER. The second issue is related with the increased density of lithographic patterns and the special characteristics of DSA and MP lithography patterns exhibits. In a previous work, we presented an enlarged LER characterization methodology for such patterns, which includes updated versions of the old metrics along with new metrics defined and developed to capture cross-edge and cross-line correlations. The fundamental concept has been the Line Center Roughness (LCR), the edge c-factor and the line c-factor correlation function and length quantifying the line fluctuations and the extent of cross-edge and cross-line correlations. In this work, we focus on the role of etch steps on cross-edge and line correlation metrics in SAQP data. We find that the spacer etch steps reduce edge correlations while etch steps with pattern transfer increase these. Furthermore, the density doubling and quadrupling increase edge correlations as well as cross-line correlations.

Human engineer's guide to auditory displays. Volume 1. Elements of perception and memory affecting auditory displays

NASA Astrophysics Data System (ADS)

Mulligan, B. E.; Goodman, L. S.; McBride, D. K.; Mitchell, T. M.; Crosby, T. N.

1984-08-01

This work reviews the areas of auditory attention, recognition, memory and auditory perception of patterns, pitch, and loudness. The review was written from the perspective of human engineering and focuses primarily on auditory processing of information contained in acoustic signals. The impetus for this effort was to establish a data base to be utilized in the design and evaluation of acoustic displays.

Psychological and Metabolic Correlates of Obesity in African-Americans and Caucasians

DTIC Science & Technology

2006-07-24

any infectious disease epidemic” (Hall & Jones, 2002, p. 657). Over the last several decades, Americans have shifted toward high fat diets, modern... cardiovascular disease , and greater likelihood to gain more body fat (Garner & Wooley, 1991). The pattern of weight cycling may negatively affect the...Furthermore, the cardiovascular literature suggests that African-Americans also tend to adopt the active coping strategy of John Henryism in which hard work

Depletion force induced collective motion of microtubules driven by kinesin

NASA Astrophysics Data System (ADS)

Inoue, Daisuke; Mahmot, Bulbul; Kabir, Arif Md. Rashedul; Farhana, Tamanna Ishrat; Tokuraku, Kiyotaka; Sada, Kazuki; Konagaya, Akihiko; Kakugo, Akira

2015-10-01

Collective motion is a fascinating example of coordinated behavior of self-propelled objects, which is often associated with the formation of large scale patterns. Nowadays, the in vitro gliding assay is being considered a model system to experimentally investigate various aspects of group behavior and pattern formation by self-propelled objects. In the in vitro gliding assay, cytoskeletal filaments F-actin or microtubules are driven by the surface immobilized associated biomolecular motors myosin or dynein respectively. Although the F-actin/myosin or microtubule/dynein system was found to be promising in understanding the collective motion and pattern formation by self-propelled objects, the most widely used biomolecular motor system microtubule/kinesin could not be successfully employed so far in this regard. Failure in exhibiting collective motion by kinesin driven microtubules is attributed to the intrinsic properties of kinesin, which was speculated to affect the behavior of individual gliding microtubules and mutual interactions among them. In this work, for the first time, we have demonstrated the collective motion of kinesin driven microtubules by regulating the mutual interaction among the gliding microtubules, by employing a depletion force among them. Proper regulation of the mutual interaction among the gliding microtubules through the employment of the depletion force was found to allow the exhibition of collective motion and stream pattern formation by the microtubules. This work offers a universal means for demonstrating the collective motion using the in vitro gliding assay of biomolecular motor systems and will help obtain a meticulous understanding of the fascinating coordinated behavior and pattern formation by self-propelled objects.Collective motion is a fascinating example of coordinated behavior of self-propelled objects, which is often associated with the formation of large scale patterns. Nowadays, the in vitro gliding assay is being considered a model system to experimentally investigate various aspects of group behavior and pattern formation by self-propelled objects. In the in vitro gliding assay, cytoskeletal filaments F-actin or microtubules are driven by the surface immobilized associated biomolecular motors myosin or dynein respectively. Although the F-actin/myosin or microtubule/dynein system was found to be promising in understanding the collective motion and pattern formation by self-propelled objects, the most widely used biomolecular motor system microtubule/kinesin could not be successfully employed so far in this regard. Failure in exhibiting collective motion by kinesin driven microtubules is attributed to the intrinsic properties of kinesin, which was speculated to affect the behavior of individual gliding microtubules and mutual interactions among them. In this work, for the first time, we have demonstrated the collective motion of kinesin driven microtubules by regulating the mutual interaction among the gliding microtubules, by employing a depletion force among them. Proper regulation of the mutual interaction among the gliding microtubules through the employment of the depletion force was found to allow the exhibition of collective motion and stream pattern formation by the microtubules. This work offers a universal means for demonstrating the collective motion using the in vitro gliding assay of biomolecular motor systems and will help obtain a meticulous understanding of the fascinating coordinated behavior and pattern formation by self-propelled objects. Electronic supplementary information (ESI) available. See DOI: 10.1039/c5nr02213d

Influence of gravity compensation training on synergistic movement patterns of the upper extremity after stroke, a pilot study

PubMed Central

2012-01-01

Background The majority of stroke patients have to cope with impaired arm function. Gravity compensation of the arm instantaneously affects abnormal synergistic movement patterns. The goal of the present study is to examine whether gravity compensated training improves unsupported arm function. Methods Seven chronic stroke patients received 18 half-hour sessions of gravity compensated reach training, in a period of six weeks. During training a motivating computer game was played. Before and after training arm function was assessed with the Fugl-Meyer assessment and a standardized, unsupported circle drawing task. Synergistic movement patterns were identified based on concurrent changes in shoulder elevation and elbow flexion/extension angles. Results Median increase of Fugl-Meyer scores was 3 points after training. The training led to significantly increased work area of the hemiparetic arm, as indicated by the normalized circle area. Roundness of the drawn circles and the occurrence of synergistic movement patterns remained similar after the training. Conclusions A decreased strength of involuntary coupling might contribute to the increased arm function after training. More research is needed to study working mechanisms involved in post stroke rehabilitation training. The used training setup is simple and affordable and is therefore suitable to use in clinical settings. PMID:22824488

Template-guided highly aligned, nano-scale wrinkle structure on a large-area

NASA Astrophysics Data System (ADS)

Lim, Jongcheon; Kim, Pilnam

This study presents a novel technique to induce aligned, nano-scale wrinkle on a polysiloxane-based UV curable resin. There have been studies on generating randomized sub-micron wrinkle using oxygen plasma treatment which causes equibiaxial compressive stress on the film surface. Few works have been reported on how to control the surface wrinkle orientation. Currently available approaches for regulating the wrinkle pattern typically require polydimethylsiloxane (PDMS)-based bilayer system under uniaxial stress condition which hampers various technological applications. Here, we demonstrate a method to generate aligned wrinkle with UV curable polymers. Highly regular array of nanoscale wrinkles were formed by elastic buckling of bilayered UV curable resin, resulting from a combination of confinement effect and anchor-guided propagation of structure. The wrinkle tends to align uniformly lateral to the template pattern as the resin filled in the pattern forms more convex meniscus. The wavelength of the wrinkle was controlled by UV exposure time yielding as small as 170nm. From our results, we suggest the confinement provided by the template pattern may have affected the direction of thin film's expansion yielding unidirectional compressive stress. This work was supported by Samsung Research Funding Center of Samsung Electronics under Project Number SRFC-IT1402-02.

Firefighter injuries are not just a fireground problem.

PubMed

Frost, D M; Beach, T A C; Crosby, I; McGill, S M

2015-01-01

Linking firefighter injury reporting to general motion patterns may provide insight into potential injury mechanisms and the development of prevention strategies. To characterize the injuries sustained by members of a large Canadian metropolitan fire department over a 5-year span. Data were taken from injury reports filed by career firefighters between 2007 and 2011. Injuries were described by job duty, type, body part affected, and the general motion pattern employed at the time of injury (e.g. lifting). Of the 1311 injuries reported, 64% were categorized as sprains and strains (musculoskeletal disorders -MSDs), the most frequent of which affected the back (32%). Categorized by job duty, 65% of MSDs were sustained while working at the fire station or during physical training-related activities. Only 15% were attributed to fireground operations. Furthermore, the associated job duty could not differentiate the types of injuries sustained; back injuries occurred primarily while lifting, knee injuries while stepping, and shoulder injuries during pushing/pulling-related activities. Firefighter injuries are not just a fireground problem. Injury causation may be better understood by linking the injury location and type with motion patterns rather than job duties. This information could assist in developing general prevention strategies for the fire service.

Phonological and Lexical Effects in Verbal Recall by Children with Specific Language Impairments

PubMed Central

Coady, Jeffry A.; Mainela-Arnold, Elina; Evans, Julia L.

2014-01-01

Background & Aims The present study examined how phonological and lexical knowledge influences memory in children with specific language impairments (SLI). Previous work showed recall advantages for typical adults and children due to word frequency and phonotactic pattern frequency and a recall disadvantage due to phonological similarity among words. While children with SLI have well documented memory difficulties, it is not clear whether these language knowledge factors also influence recall in this population. Methods & Procedures 16 children with SLI (mean age 10;2) and CAM controls recalled lists of words differing in phonological similarity, word frequency, and phonotactic pattern frequency. While previous studies used a small set of words appearing in multiple word lists, the current study used a larger set of words, without replacement, so that children could not gain practice with individual test items. Outcomes & Results All main effects were significant. Interactions revealed that children with SLI were affected by similarity, but less so than their peers, comparably affected by word frequency, and unaffected by phonotactic pattern frequency. Conclusions Results due to phonological similarity suggest that children with SLI use less efficient encoding, while results due to word frequency and phonotactic pattern frequency were mixed. Children with SLI used coarse-grained language knowledge (word frequency) comparably to peers, but were less able to use fine-grained knowledge (phonotactic pattern frequency). Paired with phonological similarity results, this suggests that children with SLI have difficulty establishing robust phonological knowledge for use in language tasks. PMID:23472955

[Dynamics of ecological landscape pattern and its affecting factors in desert-oasis in Fukang, Xinjiang].

PubMed

Liu, Xinchun; Zhang, Yuandong; Ren, Guangyao; Pan, Xiaoling; He, Qing

2004-07-01

The spatial pattern of ecological landscape during land utilization in Fukang is heavily influenced by natural difference and the scale of water and land resource development. Analyses on the spatial pattern based on different zones and indexes showed that from 1987 to 1998, the change of the spatial pattern of ecological landscape during land utilization in Fukang was mainly the increase of plantation area in pluvial fan and the decrease in alluvial plain. The case was on the contrary about badlands. The acreage of woodland decreased in lower mountains, uplands and alluvial plain, but no variety in alluvial plain. The acreage of grassland increased in lower mountains and uplands, while decreased in other fields. The acreage of town increased in each sample field, while that of water area remained uncharged. The landscape diversity and evenness was descending, the dominance was ascending in lower mountains and in pluvial fan, while it was reverse in alluvial plain. Accessorial fragmentation showed the increasing influence of human beings. The change of the spatial pattern of ecological landscape in Fukang focused on the acreage alteration of plantation and badlands in pluvial fan and alluvial plain. The key factor was the dynamic variation of water-salt in water and soil resource utilization. Terrain and land utilization were the key factors affecting water table, and the continuous changes of the water table worked on the spatial distribution of soil water-salt.

Women in dentistry in South Africa: a survey of their experiences and opinions.

PubMed

Naidoo, S

2005-08-01

Women form an increasingly important part of the dentally trained workforce in South Africa. However, little is known about the professional issues and work-related problems affecting women dentists. A postal survey was undertaken of registered female dental practitioners in the country, with the aim to document their experiences. The survey (i) ascertained their current pattern of work, (ii) identified factors influencing their work patterns and (iii) identified factors that would help women remain in the profession or re-enter it more easily after an absence. A self-administered 50-item questionnaire containing open and closed-ended questions was used. Questions related to professional status, working patterns, practice ownership, postgraduate qualifications and career satisfaction. Nine hundred and sixty questionnaires were sent out and 280 were returned (29% response rate). Although a significant majority were currently practicing (96%), about 20% were employed or worked part-time and 7 reported that they were not in practice at the time of the survey for various reasons including maternity leave, ill-health, retirement or that they were now working outside the dental field. Major factors identified in this study were the women's dual responsibility at home and at work. Few women find themselves in specialist practice, although 68% indicated that they would liked to have specialised. Home responsibilities and inflexible working conditions were commonly reported difficulties experienced with further studies. In addition, the lack of part-time training and the geographical location of training facilities also played a role. Women dentists need more flexible working schedules and conditions of employment. Part-time training and part-time career options should be extended. Retraining and refresher courses for Women dentists who have had a break in their careers should be available to enable them to return sooner and more easily to practice. Tertiary training dental facilities throughout the country should take up this challenge and run courses that are tailored to the local need and domestic commitments of the women involved.

Clinicopathological patterns and distribution of Schistosomiasis in Asir Region.

PubMed

Morad, N A; Khan, A R

2001-06-01

The objective of this study is to report, for the first time, the histopathologic pattern of Schistosomiasis from the Asir Region and to compare it to patterns reported from other regions of the Kingdom of Saudi Arabia. Several studies have reported the patterns of Schistosomiasis in other regions of the Kingdom of Saudi Arabia and other countries where Schistosomiasis is endemic. Schistosomiasis is endemic in certain areas of Asir region, however no data is available concerning the clinicopathological pattern of Schistosomiasis in the Asir Region. This is a retrospective analysis of 217 cases of Schistosomiasis from surgical and biopsy files of Asir Central Hospital during a period from January 1990 to October 1999. Our study revealed that Schistosomiasis was more common among the expatriate population of Asir Region than Saudi nationals residing in this area. The urinary tract was most commonly involved, and then in descending frequency came the vermiform appendix, liver and large bowel. These findings are somewhat different from those observed in the Riyadh Region where the vermiform appendix was the most commonly affected organ. Based on the histopathologic pattern, our study describes the pattern of Schistosomiasis in the Asir Region and may serve as a base-line for future research work.

Working memory in social anxiety disorder: better manipulation of emotional versus neutral material in working memory.

PubMed

Yoon, K Lira; Kutz, Amanda M; LeMoult, Joelle; Joormann, Jutta

2017-12-01

Individuals with social anxiety disorder (SAD) engage in post-event processing, a form of perseverative thinking. Given that deficits in working memory might underlie perseverative thinking, we examined working memory in SAD with a particular focus on the effects of stimulus valence. SAD (n = 31) and healthy control (n = 20) participants either maintained (forward trials) or reversed (backward trials) in working memory the order of four emotional or four neutral pictures, and we examined sorting costs, which reflect the extent to which performance deteriorated on the backward trials compared to the forward trials. Emotionality of stimuli affected performance of the two groups differently. Whereas control participants exhibited higher sorting costs for emotional stimuli compared to neutral stimuli, SAD participants exhibited the opposite pattern. Greater attention to emotional stimuli in SAD might facilitate the processing of emotional (vs. neutral) stimuli in working memory.

Acquisition of English word stress patterns in early and late bilinguals

NASA Astrophysics Data System (ADS)

Guion, Susan G.

2004-05-01

Given early acquisition of prosodic knowledge as demonstrated by infants' sensitivity to native language accentual patterns, the question of whether learners can acquire new prosodic patterns across the life span arises. Acquisition of English stress by early and late Spanish-English and Korean-English bilinguals was investigated. In a production task, two-syllable nonwords were produced in noun and verb sentence frames. In a perception task, preference for first or last syllable stress on the nonwords was indicated. Also, real words that were phonologically similar to the nonwords were collected. Logistic regression analyses and ANOVAs were conducted to determine the effect of three factors (syllable structure, lexical class, and stress patterns of phonologically similar words) on the production and perception responses. In all three groups, stress patterns of phonologically similar real words predicted stress on nonwords. For the two other factors, early bilinguals patterned similarly to the native-English participants. Late Spanish-English bilinguals demonstrated less learning of stress patterns based on syllabic structure, and late Korean-English bilinguals demonstrated less learning of stress patterns based on lexical class than native-English speakers. Thus, compared to native speakers, late bilinguals' ability to abstract stress patterns is reduced and affected by the first language. [Work supported by NIH.

Coparenting Around Siblings’ Differential Treatment in Mexican-Origin Families

PubMed Central

Solmeyer, Anna R.; Killoren, Sarah E.; McHale, Susan M.; Updegraff, Kimberly A.

2011-01-01

This study examined patterns of mothers’ and fathers’ differential affection and discipline toward two adolescent offspring in 243 Mexican-origin families. Grounding our work in a family systems perspective, we used interparental patterns of differential treatment as an index of the coparental alliance and tested their associations with parents’ reports of familism values, traditional gender role attitudes, and cultural orientations. We also sought to replicate prior research on European American samples linking interparental patterns of differential treatment to marital qualities (coparenting satisfaction, love, and conflict) and adolescent depressive symptoms and risky behaviors. Three interparental patterns emerged: families in which both mothers and fathers treated their two offspring equally, incongruent families in which one parent treated both offspring equally while the other parent favored one offspring, and congruent families in which both parents favored the same offspring. Most parents reported equal treatment, but others fell into the incongruent affection (30%), incongruent discipline (45%), and congruent discipline (16%) groups. Mixed model ANOVAs revealed that in families in which mothers and fathers both treated their offspring equally, parents reported higher familism values, more traditional gender role attitudes, and relatively stronger orientations to Mexican than Anglo culture. Consistent with previous research, interparental incongruence was associated with less positive marital qualities and more adolescent adjustment problems. Discussion focuses on the role of culture in shaping coparenting and the processes through which these coparenting dynamics are linked to marital and youth adjustment. PMID:21480704

Affect Dynamics, Affective Forecasting, and Aging

PubMed Central

Nielsen, Lisbeth; Knutson, Brian; Carstensen, Laura L.

2008-01-01

Affective forecasting, experienced affect, and recalled affect were compared in younger and older adults during a task in which participants worked to win and avoid losing small monetary sums. Dynamic changes in affect were measured along valence and arousal dimensions, with probes during both anticipatory and consummatory task phases. Older and younger adults displayed distinct patterns of affect dynamics. Younger adults reported increased negative arousal during loss anticipation and positive arousal during gain anticipation. In contrast, older adults reported increased positive arousal during gain anticipation but showed no increase in negative arousal on trials involving loss anticipation. Additionally, younger adults reported large increases in valence after avoiding an anticipated loss, but older adults did not. Younger, but not older, adults exhibited forecasting errors on the arousal dimension, underestimating increases in arousal during anticipation of gains and losses and overestimating increases in arousal in response to gain outcomes. Overall, the findings are consistent with a growing literature suggesting that older people experience less negative emotion than their younger counterparts and further suggest that they may better predict dynamic changes in affect. PMID:18540748

Maternal negative affect during infancy is linked to disrupted patterns of diurnal cortisol and alpha asymmetry across contexts during childhood.

PubMed

Brooker, Rebecca J; Davidson, Richard J; Goldsmith, H Hill

2016-02-01

Maternal negative affect in the early environment is believed to sensitize long-term coping capacities in children. Yet, little work has identified physiological systems associated with coping responses, which may serve as mechanisms for links between early maternal negativity and child outcomes. Using a longitudinal twin sample (N=89), we found that high levels of maternal negative affect during infancy were associated with dysregulation of diurnal cortisol and electroencephalograph (EEG) asymmetry, two physiological systems that may support active approach-oriented coping when children are 7years old. Flattened slopes of diurnal cortisol were also associated with greater numbers of concurrent overanxious behaviors in children. A mediation analysis supported the role of dysregulated diurnal cortisol as a mediator of the link between maternal negative affect in the early environment and childhood risk for anxiety problems. Copyright © 2015 Elsevier Inc. All rights reserved.

Faunal responses to fire in chaparral and sage scrub in California, USA

USGS Publications Warehouse

van Mantgem, Elizabeth; Keeley, Jon E.; Witter, Marti

2015-01-01

Impact of fire on California shrublands has been well studied but nearly all of this work has focused on plant communities. Impact on and recovery of the chaparral fauna has received only scattered attention; this paper synthesizes what is known in this regard for the diversity of animal taxa associated with California shrublands and outlines the primary differences between plant and animal responses to fire. We evaluated the primary faunal modes of resisting fire effects in three categories: 1) endogenous survival in a diapause or diapause-like stage, 2) sheltering in place within unburned refugia, or 3) fleeing and recolonizing. Utilizing these patterns in chaparral and sagescrub, as well as some studies on animals in other mediterranean-climate ecosystems, we derived generalizations about how plants and animals differ in their responses to fire impacts and their post fire recovery. One consequence of these differences is that variation in fire behavior has a much greater potential to affect animals than plants. For example, plants recover from fire endogenously from soil-stored seeds and resprouts, so fire size plays a limited role in determining recovery patterns. However, animals that depend on recolonization of burned sites from metapopulations may be greatly affected by fire size. Animal recolonization may also be greatly affected by regional land use patterns that affect colonization corridors, whereas such regional factors play a minimal role in plant community recovery. Fire characteristics such as rate of spread and fire intensity do not appear to play an important role in determining patterns of chaparral and sage scrub plant recovery after fire. However, these fire behavior characteristics may have a profound role in determining survivorship of some animal populations as slow-moving, smoldering combustion may limit survivorship of animals in burrows, whereas fast-moving, high intensity fires may affect survivorship of animals in above ground refugia or those attempting to flee. Thus, fire regime characteristics may have a much greater effect on postfire recovery of animal communities than plant communities in these shrubland ecosystems.

Novel Kinetic Strategies Adopted in Asymmetric Split-Belt Treadmill Walking.

PubMed

Hinkel-Lipsker, Jacob W; Hahn, Michael E

2016-01-01

The hip and ankle strategies that affect learning of a novel gait have not been fully determined, and could be of importance in design of clinical gait interventions. The authors' purpose was to determine the effects of asymmetric split-belt treadmill walking on ankle and hip work during propulsion. Participants were randomized into either a gradual training group or a sudden training group and later returned for a retention test. The gradual training group performed significantly more work at the hip joint of the slow limb during acquisition, and decreased the hip joint work performed during retention. These findings reveal the hip joint on the slow limb during initial swing as a possible site of adaptation to a novel locomotor pattern.

Cellular pattern formation by SCRAMBLED, a leucine-rich repeat receptor-like kinase in Arabidopsis.

PubMed

Kwak, Su-Hwan; Schiefelbein, John

2008-02-01

The appropriate specification of distinct cell types is important for generating the proper tissues and bodies of multicellular organisms. In the root epidermis of Arabidopsis, cell fate determination is accomplished by a transcriptional regulatory circuit that is influenced by positional signaling. A leucine-rich repeat receptor-like kinase, SCRAMBLED (SCM), has been shown to be responsible for the position-dependent aspect of this epidermal pattern. In a recent report, we find that SCM affects the transcriptional regulatory network by down-regulating the WEREWOLF (WER) MYB gene expression in a set of epidermal cells located in a specific position. We also find that SCM and the SCM-related SRF1 and SRF3 are not required for embryonic epidermal patterning and that SRF1 and SRF3 do not act redundantly with SCM. This suggests that distinct positional signaling mechanisms exist for embryonic and post-embryonic epidermal patterning. In this addendum, we discuss the implications of our recent findings and extend our working model for epidermal cell pattering.

Cellular pattern formation by SCRAMBLED, a leucine-rich repeat receptor-like kinase in Arabidopsis

PubMed Central

Kwak, Su-Hwan

2008-01-01

The appropriate specification of distinct cell types is important for generating the proper tissues and bodies of multicellular organisms. In the root epidermis of Arabidopsis, cell fate determination is accomplished by a transcriptional regulatory circuit that is influenced by positional signaling. A leucine-rich repeat receptor-like kinase, SCRAMBLED (SCM), has been shown to be responsible for the position-dependent aspect of this epidermal pattern. In a recent report, we find that SCM affects the transcriptional regulatory network by down-regulating the WEREWOLF (WER) MYB gene expression in a set of epidermal cells located in a specific position. We also find that SCM and the SCM-related SRF1 and SRF3 are not required for embryonic epidermal patterning and that SRF1 and SRF3 do not act redundantly with SCM. This suggests that distinct positional signaling mechanisms exist for embryonic and post-embryonic epidermal patterning. In this addendum, we discuss the implications of our recent findings and extend our working model for epidermal cell pattering. PMID:19704725

Spatiotemporal throughfall patterns beneath an urban tree row

NASA Astrophysics Data System (ADS)

Bogeholz, P.; Van Stan, J. T., II; Hildebrandt, A.; Friesen, J.; Dibble, M.; Norman, Z.

2016-12-01

Much recent research has focused on throughfall patterns in natural forests as they can influence the heterogeneity of surface ecohydrological and biogeochemical processes. However, to the knowledge of the authors, no work has assessed how urban forest structures affect the spatiotemporal variability of throughfall water flux. Urbanization greatly alters not only a significant portion of the land surface, but canopy structure, with the most typical urban forest configuration being landscaped tree rows along streets, swales, parking lot medians, etc. This study examines throughfall spatiotemporal patterns for a landscaped tree row of Pinus elliottii (Engelm., slash pine) on Georgia Southern University's campus (southeastern, USA) using 150 individual observations per storm. Throughfall correlation lengths beneath this tree row were similar to, but appeared to be more stable across storm size than, observations in past studies on natural forests. Individual tree overlap and the planting interval also may more strongly drive throughfall patterns in tree rows. Meteorological influences beyond storm magnitude (intensity, intermittency, wind conditions, and atmospheric moisture demand) are also examined.

Transthoracic Ultrafast Doppler Imaging of Human Left Ventricular Hemodynamic Function

PubMed Central

Osmanski, Bruno-Félix; Maresca, David; Messas, Emmanuel; Tanter, Mickael; Pernot, Mathieu

2016-01-01

Heart diseases can affect intraventricular blood flow patterns. Real-time imaging of blood flow patterns is challenging because it requires both a high frame rate and a large field of view. To date, standard Doppler techniques can only perform blood flow estimation with high temporal resolution within small regions of interest. In this work, we used ultrafast imaging to map in 2D human left ventricular blood flow patterns during the whole cardiac cycle. Cylindrical waves were transmitted at 4800 Hz with a transthoracic phased array probe to achieve ultrafast Doppler imaging of the left ventricle. The high spatio-temporal sampling of ultrafast imaging permits to rely on a much more effective wall filtering and to increase sensitivity when mapping blood flow patterns during the pre-ejection, ejection, early diastole, diastasis and late diastole phases of the heart cycle. The superior sensitivity and temporal resolution of ultrafast Doppler imaging makes it a promising tool for the noninvasive study of intraventricular hemodynamic function. PMID:25073134

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nesterova, E.V.; Bouvier, S.; Bacroix, B.

Transmission electron microscopy (TEM) microstructures of a high-strength dual-phase steel DP800 have been examined after moderate plastic deformations in simple shear and uniaxial tension. Special attention has been paid to the effect of the intergranular hard phase (martensite) on the microstructure evolution in the near-grain boundary regions. Quantitative parameters of dislocation patterning have been determined and compared with the similar characteristics of previously examined single-phase steels. The dislocation patterning in the interiors of the ferrite grains in DP800 steel is found to be similar to that already observed in the single-phase IF (Interstitial Free) steel whereas the martensite-affected zones presentmore » a delay in patterning and display very high gradients of continuous (gradual) disorientations associated with local internal stresses. The above stresses are shown to control the work-hardening of dual-phase materials at moderate strains for monotonic loading and are assumed to influence their microstructure evolution and mechanical behavior under strain-path changes. - Highlights: • The microstructure evolution has been studied by TEM in a DP800 steel. • It is influenced by both martensite and dislocations in the initial state. • The DP800 steel presents a high work-hardening rate due to internal stresses.« less

Identifying ADHD children using hemodynamic responses during a working memory task measured by functional near-infrared spectroscopy

NASA Astrophysics Data System (ADS)

Gu, Yue; Miao, Shuo; Han, Junxia; Liang, Zhenhu; Ouyang, Gaoxiang; Yang, Jian; Li, Xiaoli

2018-06-01

Objective. Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder affecting children and adults. Previous studies found that functional near-infrared spectroscopy (fNIRS) can reveal significant group differences in several brain regions between ADHD children and healthy controls during working memory tasks. This study aimed to use fNIRS activation patterns to identify ADHD children from healthy controls. Approach. FNIRS signals from 25 ADHD children and 25 healthy controls performing the n-back task were recorded; then, multivariate pattern analysis was used to discriminate ADHD individuals from healthy controls, and classification performance was evaluated for significance by the permutation test. Main results. The results showed that 86.0% (p<0.001 ) of participants can be correctly classified in leave-one-out cross-validation. The most discriminative brain regions included the bilateral dorsolateral prefrontal cortex, inferior medial prefrontal cortex, right posterior prefrontal cortex, and right temporal cortex. Significance. This study demonstrated that, in a small sample, multivariate pattern analysis can effectively identify ADHD children from healthy controls based on fNIRS signals, which argues for the potential utility of fNIRS in future assessments.

Manipulating the Coffee-Ring Effect: Interactions at Work.

PubMed

Anyfantakis, Manos; Baigl, Damien

2015-07-31

The evaporation of a drop of colloidal suspension pinned on a substrate usually results in a ring of particles accumulated at the periphery of the initial drop. Intense research has been devoted to understanding, suppressing and ultimately controlling this so-called coffee-ring effect (CRE). Although the crucial role of flow patterns in the CRE has been thoroughly investigated, the effect of interactions on this phenomenon has been largely neglected. This Concept paper reviews recent works in this field and shows that the interactions of colloids with (and at) liquid-solid and liquid-gas interfaces as well as bulk particle-particle interactions drastically affect the morphology of the deposit. General rules are established to control the CRE by tuning these interactions, and guidelines for the rational physicochemical formulation of colloidal suspensions capable of depositing particles in desirable patterns are provided. This opens perspectives for the reliable control of the CRE in real-world formulations and creates new paradigms for flexible particle patterning at all kinds of interfaces as well for the exploitation of the CRE as a robust and inexpensive diagnostic tool. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Experimental study of surface pattern effects on the propulsive performance and wake of a bio-inspired pitching panel

NASA Astrophysics Data System (ADS)

King, Justin; Kumar, Rajeev; Green, Melissa

2016-11-01

Force measurements and stereoscopic particle image velocimetry (PIV) were used to characterize the propulsive performance and wake structure of rigid, bio-inspired trapezoidal pitching panels. In the literature, it has been demonstrated that quantities such as thrust coefficient and propulsive efficiency are affected by changes in the surface characteristics of a pitching panel or foil. More specifically, the variation of surface pattern produces significant changes in wake structure and dynamics, especially in the distribution of vorticity in the wake. Force measurements and PIV data were collected for multiple surface patterns chosen to mimic fish surface morphology over a Strouhal number range of 0.17 to 0.56. Performance quantities are compared with the three-dimensional vortex wake structure for both the patterned and smooth panels to determine the nature and magnitude of surface pattern effects in terms of thrust produced, drag reduced, and wake vortices reshaped and reorganized. This work was supported by the Office of Naval Research under ONR Award No. N00014-14-1-0418.

Health promoting leadership practices in four Norwegian industries.

PubMed

Skarholt, Kari; Blix, Elisabeth H; Sandsund, Mariann; Andersen, Thale K

2016-12-01

The aim of this article is to address health promoting leadership; what do leaders actually do to promote health at work? Leadership practice plays a crucial role in the workplace and greatly affects the working environment and working conditions. Through a theoretical and empirical approach, we seek to find characteristics/patterns of health promoting leadership. The definition of health promoting leadership is a democratic and supportive leadership style, where leaders seek to motivate and inspire their employees. The study in this article is based on qualitative research methods. We have investigated and compared leadership practice in four different organizations/industries in Norway: construction, oil and gas, health care and cleaning. These organizations and professions are quite different, and thus leadership must be understood and developed within its context. However, we found some generic characteristics of health promoting leadership: hands-on, accessible, supportive, inclusive and democratic. Current literature only rarely addresses how leadership affects health promotion at work. Consequently, more knowledge is needed about how leaders really succeed in creating healthy workplaces and healthy employees. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

In the era of the 24 h laboratory, does communicating Gram stain results from blood cultures flagging positive outside of conventional working hours alter patient management?

PubMed

Moore, Jonathan S; Koerner, Roland J

2015-11-01

As laboratories move towards 24 h a day working patterns, we aim to evaluate if expediting the availability of provisional blood culture results outside of normal working hours would derive clinical benefit. 116 blood cultures flagging positive outside of conventional working hours (20:00-09:00) were studied. In each case, medical records were reviewed and cases discussed with clinicians to determine if earlier communication of results would have altered management and affected the outcome. Organisms were seen in 102/116 blood cultures. In total, 76/82 (92.7%) patients with cultures deemed to be significant were on an antibiotic. The isolate was sensitive to the prescribed antibiotic in 56/74 (76%) cases. Input from a microbiologist is likely to have altered management in 14 (13.7%) cases, but unlikely to have affected any outcomes. We found no compelling evidence that expediting the availability of Gram stain results from positive blood cultures alone improves patient outcome. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Proteomics on porcine haptoglobin and IgG/IgA show protein species distribution and glycosylation pattern to remain similar in PCV2-SD infection.

PubMed

Marco-Ramell, Anna; Miller, Ingrid; Nöbauer, Katharina; Möginger, Uwe; Segalés, Joaquim; Razzazi-Fazeli, Ebrahim; Kolarich, Daniel; Bassols, Anna

2014-04-14

Haptoglobin (Hp) and immunoglobulins are plasma glycoproteins involved in the immune reaction of the organism after infection and/or inflammation. Porcine circovirus type 2-systemic disease (PCV2-SD), formerly known as postweaning multisystemic wasting syndrome (PMWS), is a globally spread pig disease of great economic impact. PCV2-SD affects the immunological system of pigs causing immunosuppression. The aim of this work was to characterize the Hp protein species of healthy and PCV2-SD affected pigs, as well as the protein backbone and the glycan chain composition of porcine Hp. PCV2-SD affected pigs had an increased overall Hp level, but it did not affect the ratio between Hp species. Glycoproteomic analysis of the Hp β subunits confirmed that porcine Hp is N-glycosylated and, unexpectedly, O-glycosylated, a PTM that is not found on Hp from healthy humans. The glyco-profile of porcine IgG and IgA heavy chains was also characterized; decreased levels of both proteins were found in the investigated group of PCV2-SD affected pigs. Obtained results indicate that no significant changes in the N- and O-glycosylation patterns of these major porcine plasma glycoproteins were detectable between healthy and PCV2-SD affected animals. PCV2-SD is a disease of great economic importance for pig production, characterized by a complex response of the immune system. In the search of a better diagnostic/prognostic marker for porcine PCV2-SD, extensive analyses of the Hp protein backbone and the glycan chains were thoroughly analyzed by various techniques. This resulted in detection and confirmation of Hp O-glycosylation and the glyco-profiling of porcine IgG and IgA. The N- and O-glycosylation of these major porcine plasma glycoproteins appears to be not affected by PCV2-SD infection. Interestingly, these data suggest that this viral infection, which significantly affects the immune responses of the host, leaves the biosynthetic glycosylation processes in the liver and immune cells unaffected. Lack of PTM changes is in contrast to findings in humans where for both proteins pattern changes have been reported in several chronic and inflammatory diseases. This underlines the importance of studying species in detail and not reaching to conclusions by analogy. Furthermore, since Hp is usually quantified by immunoassays in clinical routine analyses, our findings indicate that no bias in Hp determination capabilities due to an altered carbohydrate pattern is to be expected. Copyright © 2014 Elsevier B.V. All rights reserved.

Computational imaging with a single-pixel detector and a consumer video projector

NASA Astrophysics Data System (ADS)

Sych, D.; Aksenov, M.

2018-02-01

Single-pixel imaging is a novel rapidly developing imaging technique that employs spatially structured illumination and a single-pixel detector. In this work, we experimentally demonstrate a fully operating modular single-pixel imaging system. Light patterns in our setup are created with help of a computer-controlled digital micromirror device from a consumer video projector. We investigate how different working modes and settings of the projector affect the quality of reconstructed images. We develop several image reconstruction algorithms and compare their performance for real imaging. Also, we discuss the potential use of the single-pixel imaging system for quantum applications.

Kinetics of bed fracturing around mine workings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Veksler, Yu.A.

1988-03-01

A failure of the bed near the walls of the workings of a mine away from the face occurs gradually over time and in this paper the authors take a kinetic approach to evaluating its development. The influence of certain mine engineering factors on the pattern of bed fracturing is discussed. The effect of the depth of mining is shown. Cracking occurs in the portion of the seam at the face near the ground at some distance from it on the interface between soft and hard coal. The density of the fractured rocks and their response affect the bed fracturingmore » near the stope face.« less

Trustworthiness and Negative Affect Predict Economic Decision-Making

PubMed Central

Nguyen, Christopher M.; Koenigs, Michael; Yamada, Torricia H.; Teo, Shu Hao; Cavanaugh, Joseph E.; Tranel, Daniel; Denburg, Natalie L.

2012-01-01

The Ultimatum Game (UG) is a widely used and well-studied laboratory model of economic decision-making. Here, we studied 129 healthy adults and compared demographic (i.e., age, gender, education), cognitive (i.e., intelligence, attention/working memory, speed, language, visuospatial, memory, executive functions), and personality (i.e., “Big Five”, positive affect, negative affect) variables between those with a “rational” versus an “irrational” response pattern on the UG. Our data indicated that participants with “rational” UG performance (accepting any offer, no matter the fairness) endorsed higher levels of trust, or the belief in the sincerity and good intentions of others, while participants with “irrational” UG performance (rejecting unfair offers) endorsed higher levels of negative affect, such as anger and contempt. These personality variables were the only ones that differentiated the two response patterns—demographic and cognitive factors did not differ between rational and irrational players. The results indicate that the examination of personality and affect is crucial to our understanding of the individual differences that underlie decision-making. PMID:23493494

Young worker safety in construction: do family ties and workgroup size affect hazard exposures and safety practices?

PubMed

Rauscher, Kimberly J; Myers, Douglas J; Runyan, Carol W; Schulman, Michael

2012-01-01

Little is known about how social aspects of the work environment influence exposures or safety practices affecting young construction workers. Our objective was to investigate whether working on a construction site with a small number of workers (≤10 vs. 11-50) or having a family-firm connection (working in a family-owned firm or one in which a family member also works) impacts hazard exposures and safety practices. Participants included 187 North Carolina construction workers 14 to 17 years old who were surveyed about their jobs. We conducted stratified analyses using cross-tabulations and chi-square statistics to measure associations between workgroup size (i.e., the total number of workers on a jobsite) and family-firm connections (yes/no) and hazard exposures (e.g., saws) and safety practices (e.g., supervision). Having a family-firm connection was associated with fewer hazard exposures and greater safety practices. Youth who worked on jobsites with a larger workgroup (11-50 workers) reported more hazards but also more safety practices. Family-firm connections, in particular, may have a protective effect for youth in construction. Even though the statistical significance of our findings on workgroup size was limited in places, the pattern of differences found suggest that further research in this area is warranted.

Vegetation Patterns and Degradation Thresholds in the Mulga Landscapes of Australia

NASA Astrophysics Data System (ADS)

Azadi, Samira; Saco, Patricia; Moreno-de las Heras, Mariano; Willgoose, Garry

2017-04-01

Drylands are often characterised by a spatially heterogeneous vegetation cover forming mosaics of patches dense vegetation within bare soil. This 'patterned' or 'patchy' vegetation cover is sensitive to human pressures. Previous work suggests that within these landscapes there is a critical vegetation cover threshold below which the landscape functionality is lost. This threshold behaviour is tightly linked to the overland flow redistribution and an increase in hydrologic connectivity that induces loss of resources (i.e., leakiness). In fact, disturbances (such as wildfire, overgrazing or harvesting activities) can disrupt the spatial structure of vegetation, increase landscape hydrologic connectivity, trigger erosion and produce a substantial loss of water. All these effects affect ecosystem functionality. Here we present the results of exploring the impact of degradation processes induced by vegetation disturbances (mainly grazing) on ecosystem functionality and connectivity in semiarid landscapes with various types of vegetation patterns. The sites are carefully selected in Mulga landscapes bioregion (New South Wales, Queensland) and in sites of Northern Territory in Australia, which display similar vegetation characteristics but with different vegetation patterns and good quality rainfall information. The analysis of vegetation patterns is derived from high resolution remote sensing images (IKONOS, QuickBird, Pleiades). Using MODIS NDVI and local precipitation data, we compute rainfall use efficiency and precipitation marginal response in order to assess the ecosystem functionality. We use vegetation binary maps and digital elevation models to estimate mean Flowlength as an indicator of structural hydrologic connectivity. We compare the trends for several sites with varying vegetation patterns (i.e., banded versus spotted patterns). Our results show that disturbances increase hydrologic connectivity and suggest threshold behaviour that affects landscape functionality. Though this threshold behaviour is found in all sites, the plots in higher rainfall landscapes with banded vegetation patterns show evidence of higher resilience. We will also present some preliminary modelling results that complement this analysis and capture the coevolution of vegetation and landforms (erosion), leading to this type of threshold behaviour.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nguyen, Thien Khoi V.; Ghate, Virendra P.; Carlton, Annmarie G.

Summertime aerosol optical thickness (AOT) over the Southeast U.S. is sharply enhanced over wintertime values. This seasonal pattern is unique and of particular interest because temperatures there have not warmed over the past 100 years. Patterns in surface fine particle mass are inconsistent with satellite reported AOT. In this work, we attempt to reconcile the spatial and temporal distribution of AOT over the U.S. with particle mass measurements at the surface by examining trends in aerosol liquid water (ALW), a particle constituent that scatters radiation affecting the satellite AOT, but is removed in mass measurements at routine surface monitoring sites.more » We employ the thermodynamic model ISORROPIAv2.1 to estimate ALW mass concentrations at IMRPOVE sites using measured ion mass concentrations and NARR meteorological data. Our findings suggest ALW provides a plausible explanation for the geographical and seasonal patterns in AOT and can reconcile previously noted discrepancies with surface mass measurements.« less

Roles of safety climate and shift work on perceived injury risk: a multi-level analysis.

PubMed

Huang, Yueng-Hsiang; Chen, Jiu-Chiuan; DeArmond, Sarah; Cigularov, Konstantin; Chen, Peter Y

2007-11-01

This study evaluated the relationship between employees' work shift (i.e., day shift versus night shift) and perceptions of injury risk, and how the relationship is affected by company level safety climate and injury frequency. The results showed that night shift workers perceived a higher level of injury risk compared to day shift workers. Both company level safety climate and injury frequency played critical roles in predicting individual perceived work injury risk. Perception of injury risk of night shift workers was significantly lower when they perceived high-level rather than low-level safety climate. However, this pattern was not noticeable for day shift workers. These findings highlighted the importance of considering company level factors when attempting to understand the differences between day shift and night shift work on an individual's perception of injury risk.

Distributed Neural Processing Predictors of Multi-dimensional Properties of Affect

PubMed Central

Bush, Keith A.; Inman, Cory S.; Hamann, Stephan; Kilts, Clinton D.; James, G. Andrew

2017-01-01

Recent evidence suggests that emotions have a distributed neural representation, which has significant implications for our understanding of the mechanisms underlying emotion regulation and dysregulation as well as the potential targets available for neuromodulation-based emotion therapeutics. This work adds to this evidence by testing the distribution of neural representations underlying the affective dimensions of valence and arousal using representational models that vary in both the degree and the nature of their distribution. We used multi-voxel pattern classification (MVPC) to identify whole-brain patterns of functional magnetic resonance imaging (fMRI)-derived neural activations that reliably predicted dimensional properties of affect (valence and arousal) for visual stimuli viewed by a normative sample (n = 32) of demographically diverse, healthy adults. Inter-subject leave-one-out cross-validation showed whole-brain MVPC significantly predicted (p < 0.001) binarized normative ratings of valence (positive vs. negative, 59% accuracy) and arousal (high vs. low, 56% accuracy). We also conducted group-level univariate general linear modeling (GLM) analyses to identify brain regions whose response significantly differed for the contrasts of positive versus negative valence or high versus low arousal. Multivoxel pattern classifiers using voxels drawn from all identified regions of interest (all-ROIs) exhibited mixed performance; arousal was predicted significantly better than chance but worse than the whole-brain classifier, whereas valence was not predicted significantly better than chance. Multivoxel classifiers derived using individual ROIs generally performed no better than chance. Although performance of the all-ROI classifier improved with larger ROIs (generated by relaxing the clustering threshold), performance was still poorer than the whole-brain classifier. These findings support a highly distributed model of neural processing for the affective dimensions of valence and arousal. Finally, joint error analyses of the MVPC hyperplanes encoding valence and arousal identified regions within the dimensional affect space where multivoxel classifiers exhibited the greatest difficulty encoding brain states – specifically, stimuli of moderate arousal and high or low valence. In conclusion, we highlight new directions for characterizing affective processing for mechanistic and therapeutic applications in affective neuroscience. PMID:28959198

Internet use at workplaces and its effects on working style in indian context: An exploration

PubMed Central

Shrivastava, Apoorva; Sharma, Manoj K.; Marimuthu, P.

2016-01-01

Background: Internet use has revolutionized the pattern of working style at the workplace. It led to an increased use for nonprofessional activities at the workplace. It has been shown to affect productivity at the workplace. There is a dearth of literature from the Indian context in this area. Aim: This study was conducted to explore the pattern of Internet use at the workplace and its dysfunctions. Setting and Design: The present study was a cross-sectional prospective study. Materials and Methods: The objective of the study was to assess the pattern of technology use at the workplace. Two hundred and fifty employees having experience of Internet use for more than a year of various Government/Private sector organizations in Bengaluru were assessed using background data sheet. Users who were unwilling to participate were excluded from the study. Results: 29.6% of the participants used mobile phone exclusively. 58.8% of the participants used mobile along with other devices such as desktop, laptop, and tablet at home as well as at work. 64% of the participants reported change in their productivity due to nonwork-related Internet use at the workplace. 42% of the participants acknowledgemed postponement of their work due to Internet activities. 3–5% reported preference for Internet to work, meals, personal hygiene, sleep, and interaction with family members. WhatsApp was the most used application followed by Facebook and Gmail. Gaming applications and messenger applications such as hike and hangouts were used less frequently. Overall, delay in going to sleep was 1.6 hours and early morning awakening was 1.5 hours due to Internet use. Conclusions: The present study has implications for evolving psychoeducational modules for the promotion of healthy use of technology. PMID:28194082

Internet use at workplaces and its effects on working style in indian context: An exploration.

PubMed

Shrivastava, Apoorva; Sharma, Manoj K; Marimuthu, P

2016-01-01

Internet use has revolutionized the pattern of working style at the workplace. It led to an increased use for nonprofessional activities at the workplace. It has been shown to affect productivity at the workplace. There is a dearth of literature from the Indian context in this area. This study was conducted to explore the pattern of Internet use at the workplace and its dysfunctions. The present study was a cross-sectional prospective study. The objective of the study was to assess the pattern of technology use at the workplace. Two hundred and fifty employees having experience of Internet use for more than a year of various Government/Private sector organizations in Bengaluru were assessed using background data sheet. Users who were unwilling to participate were excluded from the study. 29.6% of the participants used mobile phone exclusively. 58.8% of the participants used mobile along with other devices such as desktop, laptop, and tablet at home as well as at work. 64% of the participants reported change in their productivity due to nonwork-related Internet use at the workplace. 42% of the participants acknowledgemed postponement of their work due to Internet activities. 3-5% reported preference for Internet to work, meals, personal hygiene, sleep, and interaction with family members. WhatsApp was the most used application followed by Facebook and Gmail. Gaming applications and messenger applications such as hike and hangouts were used less frequently. Overall, delay in going to sleep was 1.6 hours and early morning awakening was 1.5 hours due to Internet use. The present study has implications for evolving psychoeducational modules for the promotion of healthy use of technology.

EUV process improvement with novel litho track hardware

NASA Astrophysics Data System (ADS)

Stokes, Harold; Harumoto, Masahiko; Tanaka, Yuji; Kaneyama, Koji; Pieczulewski, Charles; Asai, Masaya

2017-03-01

Currently, there are many developments in the field of EUV lithography that are helping to move it towards increased HVM feasibility. Targeted improvements in hardware design for advanced lithography are of interest to our group specifically for metrics such as CD uniformity, LWR, and defect density. Of course, our work is focused on EUV process steps that are specifically affected by litho track performance, and consequently, can be improved by litho track design improvement and optimization. In this study we are building on our experience to provide continual improvement for LWR, CDU, and Defects as applied to a standard EUV process by employing novel hardware solutions on our SOKUDO DUO coat develop track system. Although it is preferable to achieve such improvements post-etch process we feel, as many do, that improvements after patterning are a precursor to improvements after etching. We hereby present our work utilizing the SOKUDO DUO coat develop track system with an ASML NXE:3300 in the IMEC (Leuven, Belgium) cleanroom environment to improve aggressive dense L/S patterns.

Dual Tasking and Working Memory in Alcoholism: Relation to Frontocerebellar Circuitry

PubMed Central

Chanraud, Sandra; Pitel, Anne-Lise; Rohlfing, Torsten; Pfefferbaum, Adolf; Sullivan, Edith V

2010-01-01

Controversy exists regarding the role of cerebellar systems in cognition and whether working memory compromise commonly marking alcoholism can be explained by compromise of nodes of corticocerebellar circuitry. We tested 17 alcoholics and 31 age-matched controls with dual-task, working memory paradigms. Interference tasks competed with verbal and spatial working memory tasks using low (three item) or high (six item) memory loads. Participants also underwent structural MRI to obtain volumes of nodes of the frontocerebellar system. On the verbal working memory task, both groups performed equally. On the spatial working memory with the high-load task, the alcoholic group was disproportionately more affected by the arithmetic distractor than were controls. In alcoholics, volumes of the left thalamus and left cerebellar Crus I volumes were more robust predictors of performance in the spatial working memory task with the arithmetic distractor than the left frontal superior cortex. In controls, volumes of the right middle frontal gyrus and right cerebellar Crus I were independent predictors over the left cerebellar Crus I, left thalamus, right superior parietal cortex, or left middle frontal gyrus of spatial working memory performance with tracking interference. The brain–behavior correlations suggest that alcoholics and controls relied on the integrity of certain nodes of corticocerebellar systems to perform these verbal and spatial working memory tasks, but that the specific pattern of relationships differed by group. The resulting brain structure–function patterns provide correlational support that components of this corticocerebellar system not typically related to normal performance in dual-task conditions may be available to augment otherwise dampened performance by alcoholics. PMID:20410871

Characterizing and Discovering Spatiotemporal Social Contact Patterns for Healthcare.

PubMed

Yang, Bo; Pei, Hongbin; Chen, Hechang; Liu, Jiming; Xia, Shang

2017-08-01

During an epidemic, the spatial, temporal and demographic patterns of disease transmission are determined by multiple factors. In addition to the physiological properties of the pathogens and hosts, the social contact of the host population, which characterizes the reciprocal exposures of individuals to infection according to their demographic structure and various social activities, are also pivotal to understanding and predicting the prevalence of infectious diseases. How social contact is measured will affect the extent to which we can forecast the dynamics of infections in the real world. Most current work focuses on modeling the spatial patterns of static social contact. In this work, we use a novel perspective to address the problem of how to characterize and measure dynamic social contact during an epidemic. We propose an epidemic-model-based tensor deconvolution framework in which the spatiotemporal patterns of social contact are represented by the factors of the tensors. These factors can be discovered using a tensor deconvolution procedure with the integration of epidemic models based on rich types of data, mainly heterogeneous outbreak surveillance data, socio-demographic census data and physiological data from medical reports. Using reproduction models that include SIR/SIS/SEIR/SEIS models as case studies, the efficacy and applications of the proposed framework are theoretically analyzed, empirically validated and demonstrated through a set of rigorous experiments using both synthetic and real-world data.

Genepleio software for effective estimation of gene pleiotropy from protein sequences.

PubMed

Chen, Wenhai; Chen, Dandan; Zhao, Ming; Zou, Yangyun; Zeng, Yanwu; Gu, Xun

2015-01-01

Though pleiotropy, which refers to the phenomenon of a gene affecting multiple traits, has long played a central role in genetics, development, and evolution, estimation of the number of pleiotropy components remains a hard mission to accomplish. In this paper, we report a newly developed software package, Genepleio, to estimate the effective gene pleiotropy from phylogenetic analysis of protein sequences. Since this estimate can be interpreted as the minimum pleiotropy of a gene, it is used to play a role of reference for many empirical pleiotropy measures. This work would facilitate our understanding of how gene pleiotropy affects the pattern of genotype-phenotype map and the consequence of organismal evolution.

Neural electrical activity and neural network growth.

PubMed

Gafarov, F M

2018-05-01

The development of central and peripheral neural system depends in part on the emergence of the correct functional connectivity in its input and output pathways. Now it is generally accepted that molecular factors guide neurons to establish a primary scaffold that undergoes activity-dependent refinement for building a fully functional circuit. However, a number of experimental results obtained recently shows that the neuronal electrical activity plays an important role in the establishing of initial interneuronal connections. Nevertheless, these processes are rather difficult to study experimentally, due to the absence of theoretical description and quantitative parameters for estimation of the neuronal activity influence on growth in neural networks. In this work we propose a general framework for a theoretical description of the activity-dependent neural network growth. The theoretical description incorporates a closed-loop growth model in which the neural activity can affect neurite outgrowth, which in turn can affect neural activity. We carried out the detailed quantitative analysis of spatiotemporal activity patterns and studied the relationship between individual cells and the network as a whole to explore the relationship between developing connectivity and activity patterns. The model, developed in this work will allow us to develop new experimental techniques for studying and quantifying the influence of the neuronal activity on growth processes in neural networks and may lead to a novel techniques for constructing large-scale neural networks by self-organization. Copyright © 2018 Elsevier Ltd. All rights reserved.

Impact of SCBA size and fatigue from different firefighting work cycles on firefighter gait.

PubMed

Kesler, Richard M; Bradley, Faith F; Deetjen, Grace S; Angelini, Michael J; Petrucci, Matthew N; Rosengren, Karl S; Horn, Gavin P; Hsiao-Wecksler, Elizabeth T

2018-04-04

Risk of slips, trips and falls in firefighters maybe influenced by the firefighter's equipment and duration of firefighting. This study examined the impact of a four self-contained breathing apparatus (SCBA) three SCBA of increasing size and a prototype design and three work cycles one bout (1B), two bouts with a five-minute break (2B) and two bouts back-to-back (BB) on gait in 30 firefighters. Five gait parameters (double support time, single support time, stride length, step width and stride velocity) were examined pre- and post-firefighting activity. The two largest SCBA resulted in longer double support times relative to the smallest SCBA. Multiple bouts of firefighting activity resulted in increased single and double support time and decreased stride length, step width and stride velocity. These results suggest that with larger SCBA or longer durations of activity, firefighters may adopt more conservative gait patterns to minimise fall risk. Practitioner Summary: The effects of four self-contained breathing apparatus (SCBA) and three work cycles on five gait parameters were examined pre- and post-firefighting activity. Both SCBA size and work cycle affected gait. The two largest SCBA resulted in longer double support times. Multiple bouts of activity resulted in more conservative gait patterns.

Resting and reactive frontal brain electrical activity (EEG) among a non-clinical sample of socially anxious adults: Does concurrent depressive mood matter?

PubMed Central

Beaton, Elliott A; Schmidt, Louis A; Ashbaugh, Andrea R; Santesso, Diane L; Antony, Martin M; McCabe, Randi E

2008-01-01

A number of studies have noted that the pattern of resting frontal brain electrical activity (EEG) is related to individual differences in affective style in healthy infants, children, and adults and some clinical populations when symptoms are reduced or in remission. We measured self-reported trait shyness and sociability, concurrent depressive mood, and frontal brain electrical activity (EEG) at rest and in anticipation of a speech task in a non-clinical sample of healthy young adults selected for high and low social anxiety. Although the patterns of resting and reactive frontal EEG asymmetry did not distinguish among individual differences in social anxiety, the pattern of resting frontal EEG asymmetry was related to trait shyness after controlling for concurrent depressive mood. Individuals who reported a higher degree of shyness were likely to exhibit greater relative right frontal EEG activity at rest. However, trait shyness was not related to frontal EEG asymmetry measured during the speech-preparation task, even after controlling for concurrent depressive mood. These findings replicate and extend prior work on resting frontal EEG asymmetry and individual differences in affective style in adults. Findings also highlight the importance of considering concurrent emotional states of participants when examining psychophysiological correlates of personality. PMID:18728822

Landscape genetics in the subterranean rodent Ctenomys "chasiquensis" associated with highly disturbed habitats from the southeastern Pampas region, Argentina.

PubMed

Mora, Matías Sebastián; Mapelli, Fernando J; López, Aldana; Gómez Fernández, María Jimena; Mirol, Patricia M; Kittlein, Marcelo J

2017-12-01

Studies of genetic differentiation in fragmented environments help us to identify those landscape features that most affect gene flow and dispersal patterns. Particularly, the assessment of the relative significance of intrinsic biological and environmental factors affecting the genetic structure of populations becomes crucial. In this work, we assess the current dispersal patterns and population structure of Ctenomys "chasiquensis", a vulnerable and endemic subterranean rodent distributed on a small area in Central Argentina, using 9 polymorphic microsatellite loci. We use landscape genetics approaches to assess the relationship between genetic connectivity among populations and environmental attributes. Our analyses show that populations of C. "chasiquensis" are moderately to highly structured at a regional level. This pattern is most likely the outcome of substantial gene flow on the more homogeneous sand dune habitat of the Northwest of its distributional range, in conjunction with an important degree of isolation of eastern and southwestern populations, where the optimal habitat is surrounded by a highly fragmented landscape. Landscape genetics analysis suggests that habitat quality and longitude were the environmental factors most strongly associated with genetic differentiation/uniqueness of populations. In conclusion, our results indicate an important genetic structure in this species, even at a small spatial scale, suggesting that contemporary habitat fragmentation increases population differentiation.

Predictors of depressive symptoms in older rural couples: the impact of work, stress and health.

PubMed

Rayens, Mary Kay; Reed, Deborah B

2014-01-01

Older farmers experience a high rate of suicide, and depression is closely aligned with suicide among agricultural workers. Depressive symptoms may be influenced by work patterns, work satisfaction, stress, and health status. In addition, members of a couple may affect each other's depressive symptoms. The purpose was to determine whether depressive symptoms score is predicted by hours worked on the farm, satisfaction with work, number of health conditions, perceived stress, and demographics in a sample of older farm couples, and to assess the degree of influence on depressive symptoms spouses have on each other. A total of 494 couples participated in the initial interview for a longitudinal study of farmers aged 50 and above. Data from husbands and wives were used together in a multilevel, dyad-based regression model to determine predictors of depressive symptoms. Men's depressive symptoms scores were predicted by their own number of health conditions and stress and by their wives' stress and health conditions. Women's depressive symptoms scores were predicted by their own work satisfaction, stress, and number of health conditions and their husbands' time spent working on the farm and stress. Stress management may be particularly important in older farm couples, since perceived duress of 1 member of the dyad impacts both. Work factors and health conditions also affect depressive symptoms in older rural couples, but these may be less easily modified. © 2013 National Rural Health Association.

Work problems due to low back pain: what do GPs do? A questionnaire survey.

PubMed

Coole, Carol; Watson, Paul J; Drummond, Avril

2010-02-01

Low back pain can affect work ability and remains a main cause of sickness absence. In the UK the GP is usually the first contact for patients seeking health care. The UK government intends that the GP will continue to be responsible for sickness certification and work advice. This role requires a considerable level of understanding of work rehabilitation, and effective communication between GPs, patients, employers and therapists. The aim of this study was to identify GPs' current practice in managing patients whose ability to work is affected by low back pain, and their perception of the support services required. A postal questionnaire of 441 GPs in the South Nottinghamshire area of the UK was carried out. Areas covered included referral patterns, sickness certification, and communication with therapists and employers. There was a 54.6% response rate. The majority of GPs (76.8%) reported that they did not take overall responsibility for managing the work problems of patients arising from low back pain. Few 'mainly agreed' that they initiated communication with employers (2.5%) and/or therapists (10.4%) regarding their patients' work. The results of this study demonstrate that most GPs do not readily engage in vocational rehabilitation and do not initiate contact with employers or other health care practitioners regarding patients' work problems. Thus the current government expectation that GPs are able to successfully manage this role may be unrealistic; considerable training and a change in the GPs' perception of their role will be required.

A non-marine source of variability in Adélie Penguin demography

USGS Publications Warehouse

Fraser, William R.; Patterson-Fraser, Donna L.; Ribic, Christine; Schofield, Oscar; Ducklow, Hugh

2013-01-01

A primary research objective of the Palmer Long Term Ecological Research (LTER) program has been to identify and understand the factors that regulate the demography of Adélie penguins (Pygoscelis adeliae). In this context, our work has been focused on variability in the marine environment on which this species depends for virtually all aspects of its life history (Ainley, 2002). As we show here, however, there are patterns evident in the population dynamics of Adélie penguins that are better explained by variability in breeding habitat quality rather than by variability in the marine system. Interactions between the geomorphology of the terrestrial environment that, in turn, affect patterns of snow deposition, drive breeding habitat quality.

Fundamental trade-offs generating the worldwide leaf economics spectrum.

PubMed

Shipley, Bill; Lechowicz, Martin J; Wright, Ian; Reich, Peter B

2006-03-01

Recent work has identified a worldwide "economic" spectrum of correlated leaf traits that affects global patterns of nutrient cycling and primary productivity and that is used to calibrate vegetation-climate models. The correlation patterns are displayed by species from the arctic to the tropics and are largely independent of growth form or phylogeny. This generality suggests that unidentified fundamental constraints control the return of photosynthates on investments of nutrients and dry mass in leaves. Using novel graph theoretic methods and structural equation modeling, we show that the relationships among these variables can best be explained by assuming (1) a necessary trade-off between allocation to structural tissues versus liquid phase processes and (2) an evolutionary tradeoff between leaf photosynthetic rates, construction costs, and leaf longevity.

Mutation of the murC and murB Genes Impairs Heterocyst Differentiation in Anabaena sp. Strain PCC 7120

PubMed Central

Videau, Patrick; Rivers, Orion S.; Ushijima, Blake; Oshiro, Reid T.; Kim, Min Joo; Philmus, Benjamin

2016-01-01

ABSTRACT To stabilize cellular integrity in the face of environmental perturbations, most bacteria, including cyanobacteria, synthesize and maintain a strong, flexible, three-dimensional peptidoglycan lattice. Anabaena sp. strain PCC 7120 is a filamentous cyanobacterium capable of differentiating morphologically distinct nitrogen-fixing heterocyst cells in a periodic pattern. While heterocyst development has been shown to require proper peptidoglycan remodeling, the role of peptidoglycan synthesis has remained unclear. Here we report the identification of two peptidoglycan synthesis genes, murC (alr5065) and murB (alr5066), as required for heterocyst development. The murC and murB genes are predicted to encode a UDP-N-acetylmuramate:l-alanine ligase and a UDP-N-acetylenolpyruvoylglucosamine reductase, respectively, and we confirm enzymatic function through complementation of Escherichia coli strains deficient for these enzymes. Cells depleted of either murC or murB expression failed to differentiate heterocysts under normally inducing conditions and displayed decreased filament integrity. To identify the stage(s) of development affected by murC or murB depletion, the spatial distribution of expression of the patterning marker gene, patS, was examined. Whereas murB depletion did not affect the pattern of patS expression, murC depletion led to aberrant expression of patS in all cells of the filament. Finally, expression of gfp controlled by the region of DNA immediately upstream of murC was enriched in differentiating cells and was repressed by the transcription factor NtcA. Collectively, the data in this work provide evidence for a direct link between peptidoglycan synthesis and the maintenance of a biological pattern in a multicellular organism. IMPORTANCE Multicellular organisms that differentiate specialized cells must regulate morphological changes such that both cellular integrity and the dissemination of developmental signals are preserved. Here we show that the multicellular bacterium Anabaena, which differentiates a periodic pattern of specialized heterocyst cells, requires peptidoglycan synthesis by the murine ligase genes murC (alr5065) and murB (alr5066) for maintenance of patterned gene expression, filament integrity, and overall development. This work highlights the significant influence that intracellular structure and intercellular connections can have on the execution of a developmental program. PMID:26811320

Mutation of the murC and murB Genes Impairs Heterocyst Differentiation in Anabaena sp. Strain PCC 7120.

PubMed

Videau, Patrick; Rivers, Orion S; Ushijima, Blake; Oshiro, Reid T; Kim, Min Joo; Philmus, Benjamin; Cozy, Loralyn M

2016-04-01

To stabilize cellular integrity in the face of environmental perturbations, most bacteria, including cyanobacteria, synthesize and maintain a strong, flexible, three-dimensional peptidoglycan lattice. Anabaena sp. strain PCC 7120 is a filamentous cyanobacterium capable of differentiating morphologically distinct nitrogen-fixing heterocyst cells in a periodic pattern. While heterocyst development has been shown to require proper peptidoglycan remodeling, the role of peptidoglycan synthesis has remained unclear. Here we report the identification of two peptidoglycan synthesis genes, murC (alr5065) and murB (alr5066), as required for heterocyst development. The murC and murB genes are predicted to encode a UDP-N-acetylmuramate:L-alanine ligase and a UDP-N-acetylenolpyruvoylglucosamine reductase, respectively, and we confirm enzymatic function through complementation of Escherichia coli strains deficient for these enzymes. Cells depleted of either murC or murB expression failed to differentiate heterocysts under normally inducing conditions and displayed decreased filament integrity. To identify the stage(s) of development affected by murC or murB depletion, the spatial distribution of expression of the patterning marker gene, patS, was examined. Whereas murB depletion did not affect the pattern of patS expression, murC depletion led to aberrant expression of patS in all cells of the filament. Finally, expression of gfp controlled by the region of DNA immediately upstream of murC was enriched in differentiating cells and was repressed by the transcription factor NtcA. Collectively, the data in this work provide evidence for a direct link between peptidoglycan synthesis and the maintenance of a biological pattern in a multicellular organism. Multicellular organisms that differentiate specialized cells must regulate morphological changes such that both cellular integrity and the dissemination of developmental signals are preserved. Here we show that the multicellular bacterium Anabaena, which differentiates a periodic pattern of specialized heterocyst cells, requires peptidoglycan synthesis by the murine ligase genes murC (alr5065) and murB (alr5066) for maintenance of patterned gene expression, filament integrity, and overall development. This work highlights the significant influence that intracellular structure and intercellular connections can have on the execution of a developmental program. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

Coparenting around siblings' differential treatment in Mexican-origin families.

PubMed

Solmeyer, Anna R; Killoren, Sarah E; McHale, Susan M; Updegraff, Kimberly A

2011-04-01

In this study we examined patterns of mothers' and fathers' differential affection and discipline toward 2 adolescent offspring in 243 Mexican-origin families. Grounding our work in a family systems perspective, we used interparental patterns of differential treatment as an index of the coparental alliance and tested their associations with parents' reports of familism values, traditional gender role attitudes, and cultural orientations. We also sought to replicate prior research on European American samples linking interparental patterns of differential treatment to marital qualities (coparenting satisfaction, love, and conflict) and adolescent depressive symptoms and risky behaviors. Three interparental patterns emerged: families in which both mothers and fathers treated their 2 offspring equally, incongruent families in which 1 parent treated both offspring equally while the other parent favored 1 offspring, and congruent families in which both parents favored the same offspring. Most parents reported equal treatment, but others fell into the incongruent affection (30%), incongruent discipline (45%), and congruent discipline (16%) groups. Mixed model analyses of variances revealed that in families in which mothers and fathers both treated their offspring equally, parents reported higher familism values, more traditional gender role attitudes, and relatively stronger orientations to Mexican than Anglo culture. Consistent with previous research, interparental incongruence was associated with less positive marital qualities and more adolescent adjustment problems. Discussion focuses on the role of culture in shaping coparenting and the processes through which these coparenting dynamics are linked to marital and youth adjustment.

Losses related to everyday occupations for adults affected by mental illness.

PubMed

Baker, Amy Elizabeth Zanker; Procter, Nicholas Gerard

2014-07-01

This paper presents findings from a larger study that explored losses from mental illness. Losses associated with occupations--a key theme from this participatory action research study--are the focus of this paper. Semi-structured in-depth interviews were carried out with 16 people who had been diagnosed with a mental illness and attended a community mental health centre. Interviews were transcribed verbatim and thematically analysed, guided by processes proposed by Dey. Numerous losses influenced participants' ability to initiate or engage in daily occupations. Some losses perpetuated further loss, at times with profound consequences, such as the loss of a house following a loss of work. Engaging in chosen occupations was often described as a longer-term goal or something participants did infrequently, due to losses such as motivation, energy, or normal sleeping patterns. The desire to work and participate in everyday occupations was emphasized and its benefits highlighted, despite previous difficulties. Implications for occupational therapists include the importance of exploring, validating, and responding to losses when these are shared, and being aware of and striving to support people experiencing losses in the areas of work, motivation, sleep patterns, and energy, which were perceived as especially challenging for participants in this study.

Sensory processing patterns predict the integration of information held in visual working memory.

PubMed

Lowe, Matthew X; Stevenson, Ryan A; Wilson, Kristin E; Ouslis, Natasha E; Barense, Morgan D; Cant, Jonathan S; Ferber, Susanne

2016-02-01

Given the limited resources of visual working memory, multiple items may be remembered as an averaged group or ensemble. As a result, local information may be ill-defined, but these ensemble representations provide accurate diagnostics of the natural world by combining gist information with item-level information held in visual working memory. Some neurodevelopmental disorders are characterized by sensory processing profiles that predispose individuals to avoid or seek-out sensory stimulation, fundamentally altering their perceptual experience. Here, we report such processing styles will affect the computation of ensemble statistics in the general population. We identified stable adult sensory processing patterns to demonstrate that individuals with low sensory thresholds who show a greater proclivity to engage in active response strategies to prevent sensory overstimulation are less likely to integrate mean size information across a set of similar items and are therefore more likely to be biased away from the mean size representation of an ensemble display. We therefore propose the study of ensemble processing should extend beyond the statistics of the display, and should also consider the statistics of the observer. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Personality, work characteristics, and employee well-being: a longitudinal analysis of additive and moderating effects.

PubMed

Houkes, Inge; Janssen, Peter P M; de Jonge, Jan; Bakker, Arnold B

2003-01-01

This study tested the longitudinal influence of personality (measured by the characteristics growth need strength, negative affectivity [NA], and upward striving) on 3 psychological outcomes (intrinsic work motivation, emotional exhaustion, and turnover intention), using a pattern of specific relationships between work characteristics and these outcomes as a framework. The study hypotheses were tested in a multioccupational sample consisting of bank employees and teachers, using a 2-wave panel design with a 1-year time interval and structural equation modeling. NA had a cross-lagged direct and additive relationship with emotional exhaustion and also moderated the relationship between Time 1 workload and Time 2 emotional exhaustion. The authors concluded that NA may have multiple effects on emotional exhaustion that persist over time.

How social factors and behavioural strategies affect feeding and social interaction patterns in pigs.

PubMed

Boumans, Iris J M M; de Boer, Imke J M; Hofstede, Gert Jan; Bokkers, Eddie A M

2018-04-26

Animals living in groups compete for food resources and face food conflicts. These conflicts are affected by social factors (e.g. competition level) and behavioural strategies (e.g. avoidance). This study aimed to deepen our understanding of the complex interactions between social factors and behavioural strategies affecting feeding and social interaction patterns in animals. We focused on group-housed growing pigs, Sus scrofa, which typically face conflicts around the feeder, and of which patterns in various competitive environments (i.e. pig:feeder ratio) have been documented soundly. An agent-based model was developed to explore how interactions among social factors and behavioural strategies can affect various feeding and social interaction patterns differently under competitive situations. Model results show that pig and diet characteristics interact with group size and affect daily feeding patterns (e.g. feed intake and feeding time) and conflicts around the feeder. The level of competition can cause a turning point in feeding and social interaction patterns. Beyond a certain point of competition, meal-based (e.g. meal frequency) and social interaction patterns (e.g. displacements) are determined mainly by behavioural strategies. The average daily feeding time can be used to predict the group size at which this turning point occurs. Under the model's assumptions, social facilitation was relatively unimportant in the causation of behavioural patterns in pigs. To validate our model, simulated patterns were compared with empirical patterns in conventionally housed pigs. Similarities between empirical and model patterns support the model results. Our model can be used as a tool in further research for studying the effects of social factors and group dynamics on individual variation in feeding and social interaction patterns in pigs, as well as in other animal species. Copyright © 2018 Elsevier Inc. All rights reserved.

Oocyte cryopreservation and in vitro culture affect calcium signalling during human fertilization.

PubMed

Nikiforaki, D; Vanden Meerschaut, F; Qian, C; De Croo, I; Lu, Y; Deroo, T; Van den Abbeel, E; Heindryckx, B; De Sutter, P

2014-01-01

What are the precise patterns of calcium oscillations during the fertilization of human oocytes matured either in vivo or in vitro or aged in vitro and what is the effect of cryopreservation? Human oocytes matured in vivo exhibit a specific pattern of calcium oscillations, which is affected by in vitro maturation, in vitro ageing and cryopreservation. Oscillations in cytoplasmic calcium concentration are crucial for oocyte activation and further embryonic development. While several studies have described in detail the calcium oscillation pattern during fertilization in animal models, studies with human oocytes are scarce. This was a laboratory-based study using human MII oocytes matured in vivo or in vitro either fresh or after cryopreservation with slow freezing or vitrification. Altogether, 205 human oocytes were included in the analysis. In vivo and in vitro matured human oocytes were used for this research either fresh or following vitrification/warming (V/W) and slow freezing/thawing (F/T). Human oocytes were obtained following written informed consent from patients undergoing ovarian hyperstimulation. For the calcium pattern analysis, oocytes were loaded with the ratiometric calcium indicator fluorescent dye Fura-2. Following ICSI using sperm from a single donor, intracellular calcium was measured for 16 h at 37°C under 6% CO(2). The calcium oscillation parameters were calculated for all intact oocytes that showed calcium oscillations and were analyzed using the Mann-Whitney U-test. Human in vivo MII oocytes display a specific pattern of calcium oscillations following ICSI. This pattern is significantly affected by in vitro ageing, with the calcium oscillations occurring over a longer period of time and with a lower frequency, shorter duration and higher amplitude (P < 0.05). In vitro matured oocytes from the GV and MI stage exhibit a different pattern of calcium oscillations with calcium transients being of lower frequency and shorter duration compared with in vivo matured MII. In MI oocytes that reached the MII stage within 3 h the calcium oscillations additionally appear over a longer period of time (P < 0.05). In vivo MII oocytes show a different calcium oscillation pattern following V/W with calcium oscillations occurring over a longer period of time, with a higher amplitude and a lower frequency (P < 0.05). In vitro matured oocytes, either from the GV or the MI stage, also display an altered pattern of calcium oscillations after V/W and the parameters that were similarly affected in all these oocyte groups are the frequency and the amplitude of the calcium transients. Slow freezing/thawing differentially affects the calcium oscillation pattern of in vitro matured and in vitro aged oocytes. The relationship between a specific pattern of calcium oscillations and subsequent human embryonic development could not be evaluated since the calcium indicator used and the high-intensity excitation light impair development. Furthermore, all oocytes were derived from stimulated cycles and immature oocytes were denuded prior to in vitro maturation. Our data show for the first time how calcium signalling during human fertilization is affected by oocyte in vitro maturation, in vitro ageing as well as V/W and slow freezing/thawing. The analysis of calcium oscillations could be used as an oocyte quality indicator to evaluate in vitro culture and cryopreservation techniques of human oocytes. This work was supported by a clinical research mandate from the Flemish Foundation of Scientific Research (FWO-Vlaanderen, FWO09/ASP/063) to F.V.M, a fundamental clinical research mandate from the FWO-Vlaanderen (FWO05/FKM/001) to P.D.S and a Ghent University grant (KAN-BOF E/01321/01) to B.H. The authors have no conflict of interest to declare.

Paraoxon and Pyridostigmine Interfere with Neural Stem Cell Differentiation

PubMed Central

Berríos, Verónica O.; Boukli, Nawal M.; Rodriguez, Jose W.; Negraes, Priscilla D.; Schwindt, Telma T.; Trujillo, Cleber A.; Oliveira, Sophia L. B.; Cubano, Luis A.; Ferchmin, P. A.; Eterovic, Vesna A.; Ulrich, Henning; Martins, Antonio H.

2015-01-01

Acetylcholinesterase (AChE) inhibition has been described as the main mechanism of organophosphate (OP)-evoked toxicity. OPs represent a human health threat, because chronic exposure to low doses can damage the developing brain, and acute exposure can produce long-lasting damage to adult brains, despite post-exposure medical countermeasures. Although the main mechanism of OP toxicity is AChE inhibition, several lines of evidence suggest that OPs also act by other mechanisms. We hypothesized that rat neural progenitor cells extracted on embryonic day 14.5 would be affected by constant inhibition of AChE from chronic exposure to OP or pyri-dostigmine (a reversible AChE blocker) during differentiation. In this work, the OP paraoxon decreased cell viability in concentrations >50 μM, as measured with the MTT assay; however, this effect was not dose-dependent. Reduced viability could not be attributed to blockade of AChE activity, since treatment with 200 μM pyri-dostigmine did not affect cell viability, even after 6 days. Although changes in protein expression patterns were noted in both treatments, the distribution of differentiated phenotypes, such as the percentages of neurons and glial cells, was not altered, as determined by flow cytometry. Since paraoxon and pyridostigmine each decreased neurite outgrowth (but did not prevent differentiation), we infer that developmental patterns may have been affected. PMID:25758980

Paraoxon and Pyridostigmine Interfere with Neural Stem Cell Differentiation.

PubMed

Berríos, Verónica O; Boukli, Nawal M; Rodriguez, Jose W; Negraes, Priscilla D; Schwindt, Telma T; Trujillo, Cleber A; Oliveira, Sophia L B; Cubano, Luis A; Ferchmin, P A; Eterović, Vesna A; Ulrich, Henning; Martins, Antonio H

2015-10-01

Acetylcholinesterase (AChE) inhibition has been described as the main mechanism of organophosphate (OP)-evoked toxicity. OPs represent a human health threat, because chronic exposure to low doses can damage the developing brain, and acute exposure can produce long-lasting damage to adult brains, despite post-exposure medical countermeasures. Although the main mechanism of OP toxicity is AChE inhibition, several lines of evidence suggest that OPs also act by other mechanisms. We hypothesized that rat neural progenitor cells extracted on embryonic day 14.5 would be affected by constant inhibition of AChE from chronic exposure to OP or pyridostigmine (a reversible AChE blocker) during differentiation. In this work, the OP paraoxon decreased cell viability in concentrations >50 μM, as measured with the MTT assay; however, this effect was not dose-dependent. Reduced viability could not be attributed to blockade of AChE activity, since treatment with 200 µM pyridostigmine did not affect cell viability, even after 6 days. Although changes in protein expression patterns were noted in both treatments, the distribution of differentiated phenotypes, such as the percentages of neurons and glial cells, was not altered, as determined by flow cytometry. Since paraoxon and pyridostigmine each decreased neurite outgrowth (but did not prevent differentiation), we infer that developmental patterns may have been affected.

Patients' Experience of Winter Depression and Light Room Treatment

PubMed Central

2017-01-01

Background. There is a need for more knowledge on the effects of light room treatment in patients with seasonal affective disorder and to explore patients' subjective experience of the disease and the treatment. Methods. This was a descriptive and explorative study applying qualitative content analysis. A purposeful sample of 18 psychiatric outpatients with a major depressive disorder with a seasonal pattern and a pretreatment score ≥12 on the 9-item Montgomery-Åsberg Depression self-rating scale was included (10 women and 8 men, aged 24–65 years). All patients had completed light room treatment (≥7/10 consecutive weekdays). Data was collected two weeks after treatment using a semistructured interview guide. Results. Patients described a clear seasonal pattern and a profound struggle to adapt to seasonal changes during the winter, including deterioration in sleep, daily rhythms, energy level, mood, activity, and cognitive functioning. Everyday life was affected with reduced work capacity, social withdrawal, and disturbed relations with family and friends. The light room treatment resulted in a radical and rapid improvement in all the major symptoms with only mild and transient side effects. Discussion. The results indicate that light room treatment is essential for some patients' ability to cope with seasonal affective disorder. PMID:28293623

Translation of near infrared brain imaging to assess children with cerebral palsy

NASA Astrophysics Data System (ADS)

Alexandrakis, George; Khan, Bilal; Tian, Fenghua; Asanani, Nayan; Behbehani, Khosrow; Delgado, Mauricio R.; Liu, Hanli

2009-02-01

Cerebral palsy (CP) is the most common motor disorder of central origin in childhood and affects at least 2 children per 1000 live births every year. Neuroimaging techniques are needed to study neuroplastic rearrangements in the human brain in vivo as a result of CP. Unfortunately, accurate imaging from currently available techniques often requires the patients' complete body confinement, steadiness and minimal noise for a long period of time, which limits the success rate to less than 50% for normal children and worse for CP-affected ones. In this work we show that functional near infrared (fNIR) imaging is robust to motion artifacts and has excellent potential as a sensitive diagnostic tool for this motor disorder. We have analyzed data from pediatric normal and CP patients performing finger-tapping and handwaving motor cortex activation tasks. From these analyses we have identified both spatial and temporal metrics of NIR-based motor cortex activation patterns that can clearly distinguish between normal and CP patients. We also present data from additional patients where signal processing methods are applied to filter out concurrently recorded hemodynamic signals due to breathing and cardiac pulsation. It is shown that filtering can substantially improve the quality of activation data, thus enabling more accurate comparison of activation patterns between normal and CP-affected children.

Justice as a dynamic construct: effects of individual trajectories on distal work outcomes.

PubMed

Hausknecht, John P; Sturman, Michael C; Roberson, Quinetta M

2011-07-01

Despite an amassing organizational justice literature, few studies have directly addressed the temporal patterning of justice judgments and the effects that changes in these perceptions have on important work outcomes. Drawing from Gestalt characteristics theory (Ariely & Carmon, 2000, 2003), we examine the concept of justice trajectories (i.e., levels and trends of individual fairness perceptions over time) and offer empirical evidence to highlight the value of considering fairness within a dynamic context. Participants included 523 working adults who completed surveys about their work experiences on 4 occasions over the course of 1 year. Results indicate that justice trends explained additional variance in distal work outcomes (job satisfaction, organizational commitment, and turnover intentions) after controlling for end-state levels of justice, demonstrating the cumulative effects of justice over time. Findings also reveal that change in procedural justice perceptions affected distal work outcomes more strongly than any other justice dimension. Implications for theory and future investigations of justice as a dynamic construct are discussed.

Determination of traffic intensity from camera images using image processing and pattern recognition techniques

NASA Astrophysics Data System (ADS)

Mehrübeoğlu, Mehrübe; McLauchlan, Lifford

2006-02-01

The goal of this project was to detect the intensity of traffic on a road at different times of the day during daytime. Although the work presented utilized images from a section of a highway, the results of this project are intended for making decisions on the type of intervention necessary on any given road at different times for traffic control, such as installation of traffic signals, duration of red, green and yellow lights at intersections, and assignment of traffic control officers near school zones or other relevant locations. In this project, directional patterns are used to detect and count the number of cars in traffic images over a fixed area of the road to determine local traffic intensity. Directional patterns are chosen because they are simple and common to almost all moving vehicles. Perspective vision effects specific to each camera orientation has to be considered, as they affect the size and direction of patterns to be recognized. In this work, a simple and fast algorithm has been developed based on horizontal directional pattern matching and perspective vision adjustment. The results of the algorithm under various conditions are presented and compared in this paper. Using the developed algorithm, the traffic intensity can accurately be determined on clear days with average sized cars. The accuracy is reduced on rainy days when the camera lens contains raindrops, when there are very long vehicles, such as trucks or tankers, in the view, and when there is very low light around dusk or dawn.

The Way the Money Goes: An Investigation of Flows of Funding and Resources for Young Children Affected by HIV/AIDS. Working Papers in Early Childhood Development. Young Children and HIV/AIDS Sub-Series, No. 37

ERIC Educational Resources Information Center

Dunn, Alison

2005-01-01

This paper discusses routes by which HIV/AIDS money is dispersed and received. It notes that capturing accurate data on actual spending patterns of large donors can be difficult, as there is no uniform tracking or reporting system and much HIV/AIDS money is spent under the broader category of sexual and reproductive health. Most of the information…

Psychosocial factors and sleep efficiency: discrepancies between subjective and objective evaluations of sleep.

PubMed

Jackowska, Marta; Dockray, Samantha; Hendrickx, Hilde; Steptoe, Andrew

2011-01-01

Self-reported sleep efficiency may not precisely reflect objective sleep patterns. We assessed whether psychosocial factors and affective responses are associated with discrepancies between subjective reports and objective measures of sleep efficiency. Participants were 199 working women aged 20 to 61 years. Standardized questionnaires were used to assess psychosocial characteristics and affect that included work stress, social support, happiness, and depressive symptoms. Objective measures of sleep were assessed on one week and one leisure night with an Actiheart monitor. Self-reported sleep efficiency was derived from the Jenkins Sleep Problems Scale. Discrepancies between self-reported and objective measures of sleep efficiency were computed by contrasting standardized measures of sleep problems with objectively measured sleep efficiency. Participants varied markedly in the discrepancies between self-reported and objective sleep measures. After adjustment for personal income, age, having children, marital status, body mass index, and negative affect, overcommitment (p = .002), low level of social support (p = .049), and poor self-rated heath (p = .02) were associated with overreporting of sleep difficulties and underestimation of sleep efficiency. Self-reported poor sleep efficiency was more prevalent among those more overcommitted at work (p = .009) and less happy (p = .02), as well as among those with lower level of social support (p = .03) and more depressive symptoms (p = .048), independently of covariates. Objective sleep efficiency was unrelated to psychosocial characteristics or affect. The extent to which self-reported evaluations of sleep efficiency reflect objective experience may be influenced by psychosocial characteristics and affect. Unless potential moderators of self-reported sleep efficiency are taken into account, associations between sleep and psychosocial factors relevant to health may be overestimated.

Laser vibrometry in the quality control of the break of tanned leather

NASA Astrophysics Data System (ADS)

Preciado, J. Sanchez; Lopez, C. Perez; Hernandez-Montes, M. del Socorro; Torre-Ibarra, M. de la; Moreno, J. M. Flores; Ruiz, C. Tavera; Mendoza Santoyo, F.; Galan, M.

2018-05-01

Tanning industry treats hides and the skin of animals for their use in products such as clothes, furniture and car's interiors. The worth of leather is highly affected by defects that may appear prior or during the tanning process. Break, which refers to the wrinkling of the grain surface of leather, is one of the main issues because it affects not only the visual appearance of leather, but also its mechanical properties. The standardized method to classify the break pattern is done by bending the leather with the hand and comparing visually the resulting wrinkles that appear with a reference pattern, which makes the classification subjective and limits the evaluation to small areas. Laser vibrometry is an optical technique that has been applied in vibrational and modal analysis, which are methodologies used to obtain the mechanical properties of materials. This work demonstrates the use of a single-point vibrometer as a noncontact and nondestructive optical method to discriminate among five break levels, which could increase the effectiveness of leather classification for quality control in the tanning industry.

How does Learning Impact Development in Infancy? The Case of Perceptual Organization

PubMed Central

Bhatt, Ramesh S.; Quinn, Paul C.

2011-01-01

Pattern perception and organization are critical functions of the visual cognition system. Many organizational processes are available early in life, such that infants as young 3 months of age are able to readily utilize a variety of cues to organize visual patterns. However, other processes are not readily evident in young infants, and their development involves perceptual learning. We describe a theoretical framework that addresses perceptual learning in infancy and the manner in which it affects visual organization and development. It identifies five kinds of experiences that induce learning, and suggests that they work via attentional and unitization mechanisms to modify visual organization. In addition, the framework proposes that this kind of learning is abstract, domain general, functional at different ages in a qualitatively similar manner, and has a long-term impact on development through a memory reactivation process. Although most models of development assume that experience is fundamental to development, very little is actually known about the process by which experience affects development. The proposed framework is an attempt to account for this process in the domain of perception. PMID:21572570

Epigenetics and lifestyle

PubMed Central

Alegría-Torres, Jorge Alejandro; Baccarelli, Andrea; Bollati, Valentina

2013-01-01

The concept of “lifestyle” includes different factors such as nutrition, behavior, stress, physical activity, working habits, smoking and alcohol consumption. Increasing evidence shows that environmental and lifestyle factors may influence epigenetic mechanisms, such as DNA methylation, histone acetylation and microRNA expression. Several lifestyle factors have been identified that might modify epigenetic patterns, such as diet, obesity, physical activity, tobacco smoking, alcohol consumption, environmental pollutants, psychological stress, and working on night shifts. Most studies conducted so far have been centered on DNA methylation, whereas only a few investigations have studied lifestyle factors in relation to histone modifications and miRNAs. Here, we review current evidence indicating that lifestyle factors might affect human health via epigenetic mechanisms. PMID:22122337

Epigenetics and lifestyle.

PubMed

Alegría-Torres, Jorge Alejandro; Baccarelli, Andrea; Bollati, Valentina

2011-06-01

The concept of 'lifestyle' includes different factors such as nutrition, behavior, stress, physical activity, working habits, smoking and alcohol consumption. Increasing evidence shows that environmental and lifestyle factors may influence epigenetic mechanisms, such as DNA methylation, histone acetylation and miRNA expression. It has been identified that several lifestyle factors such as diet, obesity, physical activity, tobacco smoking, alcohol consumption, environmental pollutants, psychological stress and working on night shifts might modify epigenetic patterns. Most of the studies conducted so far have been centered on DNA methylation, whereas only a few investigations have studied lifestyle factors in relation to histone modifications and miRNAs. This article reviews current evidence indicating that lifestyle factors might affect human health via epigenetic mechanisms.

How do geological sampling biases affect studies of morphological evolution in deep time? A case study of pterosaur (Reptilia: Archosauria) disparity.

PubMed

Butler, Richard J; Brusatte, Stephen L; Andres, Brian; Benson, Roger B J

2012-01-01

A fundamental contribution of paleobiology to macroevolutionary theory has been the illumination of deep time patterns of diversification. However, recent work has suggested that taxonomic diversity counts taken from the fossil record may be strongly biased by uneven spatiotemporal sampling. Although morphological diversity (disparity) is also frequently used to examine evolutionary radiations, no empirical work has yet addressed how disparity might be affected by uneven fossil record sampling. Here, we use pterosaurs (Mesozoic flying reptiles) as an exemplar group to address this problem. We calculate multiple disparity metrics based upon a comprehensive anatomical dataset including a novel phylogenetic correction for missing data, statistically compare these metrics to four geological sampling proxies, and use multiple regression modeling to assess the importance of uneven sampling and exceptional fossil deposits (Lagerstätten). We find that range-based disparity metrics are strongly affected by uneven fossil record sampling, and should therefore be interpreted cautiously. The robustness of variance-based metrics to sample size and geological sampling suggests that they can be more confidently interpreted as reflecting true biological signals. In addition, our results highlight the problem of high levels of missing data for disparity analyses, indicating a pressing need for more theoretical and empirical work. © 2011 The Author(s). Evolution © 2011 The Society for the Study of Evolution.

Body Temperature Patterns and Rhythmicity in Free-Ranging Subterranean Damaraland Mole-Rats, Fukomys damarensis

PubMed Central

Streicher, Sonja; Boyles, Justin G.; Oosthuizen, Maria K.; Bennett, Nigel C.

2011-01-01

Body temperature (Tb) is an important physiological component that affects endotherms from the cellular to whole organism level, but measurements of Tb in the field have been noticeably skewed towards heterothermic species and seasonal comparisons are largely lacking. Thus, we investigated patterns of Tb patterns in a homeothermic, free-ranging small mammal, the Damaraland mole-rat (Fukomys damarensis) during both the summer and winter. Variation in Tb was significantly greater during winter than summer, and greater among males than females. Interestingly, body mass had only a small effect on variation in Tb and there was no consistent pattern relating ambient temperature to variation in Tb. Generally speaking, it appears that variation in Tb patterns varies between seasons in much the same way as in heterothermic species, just to a lesser degree. Both cosinor analysis and Fast Fourier Transform analysis revealed substantial individual variation in Tb rhythms, even within a single colony. Some individuals had no Tb rhythms, while others appeared to exhibit multiple rhythms. These data corroborate previous laboratory work showing multiplicity of rhythms in mole-rats and suggest the variation seen in the laboratory is a true indicator of the variation seen in the wild. PMID:22028861

Numerical investigation of the droplet condensation on the horizontal surface with patterned wettability

NASA Astrophysics Data System (ADS)

Cho, Jaeyong; Lee, Joonsang

2017-11-01

The condensation is the one of the efficient heat transfer phenomenon that transfers the heat along an interface between two phases. This condensation is affected by the wettability of surface. Heat transfer rate can be improved by controlling the wettability of surface. Recently, the researches with patterned wettability, which is composed by a combination of hydrophilic and hydrophobic surface, have been performed to improve the heat transfer rate of condensation. In this study, we performed numerical simulation for condensation of droplet on the patterned wettability, and we analyze condensation phenomenon on the wettability pattered surface through the kinetic energy, heat flux curve, and droplet shape in the vicinity of the droplet. When we performed numerical simulations and analyzing the condensation with patterned wettability, we used the lattice Boltzmann method for the base model, and phase change was solved by Peng-Robinson equation of sate. We can find that the droplet is generated at the bottom surface and high condensation rate can be maintained on the patterned wettability. This work was also supported by the National Research Foundation of Korea (NRF) Grant funded by the Korean Government (MSIP) (No. 2015R1A5A1037668) and BrainKorea21plus.

Hybrid model for forecasting time series with trend, seasonal and salendar variation patterns

NASA Astrophysics Data System (ADS)

Suhartono; Rahayu, S. P.; Prastyo, D. D.; Wijayanti, D. G. P.; Juliyanto

2017-09-01

Most of the monthly time series data in economics and business in Indonesia and other Moslem countries not only contain trend and seasonal, but also affected by two types of calendar variation effects, i.e. the effect of the number of working days or trading and holiday effects. The purpose of this research is to develop a hybrid model or a combination of several forecasting models to predict time series that contain trend, seasonal and calendar variation patterns. This hybrid model is a combination of classical models (namely time series regression and ARIMA model) and/or modern methods (artificial intelligence method, i.e. Artificial Neural Networks). A simulation study was used to show that the proposed procedure for building the hybrid model could work well for forecasting time series with trend, seasonal and calendar variation patterns. Furthermore, the proposed hybrid model is applied for forecasting real data, i.e. monthly data about inflow and outflow of currency at Bank Indonesia. The results show that the hybrid model tend to provide more accurate forecasts than individual forecasting models. Moreover, this result is also in line with the third results of the M3 competition, i.e. the hybrid model on average provides a more accurate forecast than the individual model.

The interacting roles of climate, soils, and plant production on soil microbial communities at a continental scale

USGS Publications Warehouse

Waldrop, Mark P.; Holloway, JoAnn M.; Smith, David; Goldhaber, Martin B.; Drenovsky, R.E.; Scow, K.M.; Dick, R.; Howard, Daniel M.; Wylie, Bruce K.; Grace, James B.

2017-01-01

Soil microbial communities control critical ecosystem processes such as decomposition, nutrient cycling, and soil organic matter formation. Continental scale patterns in the composition and functioning of microbial communities are related to climatic, biotic, and edaphic factors such as temperature and precipitation, plant community composition, and soil carbon, nitrogen, and pH. Although these relationships have been well explored individually, the examination of the factors that may act directly on microbial communities vs. those that may act indirectly through other ecosystem properties has not been well developed. To further such understanding, we utilized structural equation modeling (SEM) to evaluate a set of hypotheses about the direct and indirect effects of climatic, biotic, and edaphic variables on microbial communities across the continental United States. The primary goals of this work were to test our current understanding of the interactions among climate, soils, and plants in affecting microbial community composition, and to examine whether variation in the composition of the microbial community affects potential rates of soil enzymatic activities. A model of interacting factors created through SEM shows several expected patterns. Distal factors such as climate had indirect effects on microbial communities by influencing plant productivity, soil mineralogy, and soil pH, but factors related to soil organic matter chemistry had the most direct influence on community composition. We observed that both plant productivity and soil mineral composition were important indirect influences on community composition at the continental scale, both interacting to affect organic matter content and microbial biomass and ultimately community composition. Although soil hydrolytic enzymes were related to the moisture regime and soil carbon, oxidative enzymes were also affected by community composition, reflected in the abundance of soil fungi. These results highlight that soil microbial communities can be modeled within the context of multiple interacting ecosystem properties acting both directly and indirectly on their composition and function, and this provides a rich and informative context with which to examine communities. This work also highlights that variation in climate, microbial biomass, and microbial community composition can affect maximum rates of soil enzyme activities, potentially influencing rates of decomposition and nutrient mineralization in soils.

Rotating night shift work, sleep quality, selected lifestyle factors and prolactin concentration in nurses and midwives.

PubMed

Bukowska, Agnieszka; Sobala, Wojciech; Peplonska, Beata

2015-04-01

The pattern of secretion of many hormones, including prolactin, is dependent on the circadian rhythm. Night shift work involves exposure to artificial light at night and sleep deficiency, which in turn can affect prolactin synthesis. The aim of this study was to evaluate a possible association between night shift work characteristics, sleep quality, lifestyle factors and prolactin concentration, using data from a cross-sectional study of nurses and midwives. A cross-sectional study was conducted among 327 nurses and midwives currently working on rotating night shifts, and 330 nurses and midwives working during the day (aged 40-60 years) (388 premenopausal and 269 postmenopausal). Information about night shift work characteristics, lifestyle, reproductive factors, sleep pattern and other covariates was collected through a face-to-face interview, and from a one-week work and sleep diary completed by the subjects. Weight and height were measured. Prolactin concentration was measured in the morning blood sample using the electrochemiluminesence immunoassay method. Associations were analyzed using linear regression models adjusted for important confounders. Analyses were carried out separately in pre- and postmenopausal women. None of the night shift work or sleep characteristics was significantly associated with prolactin concentration. Prolactin concentration was significantly (p < 0.05) inversely associated with smoking and time of blood sample collection. These results were consistent among both pre- and postmenopausal women. Nulliparity was significantly positively associated with prolactin among premenopausal women, but inversely among postmenopausal. Age was related to prolactin among postmenopausal women only. Our study indicates that rotating night shift work is not associated with prolactin concentration. Smoking, parity, time of blood collection and age among postmenopausal women were significant determinants of prolactin.

Working memory load affects repetitive behaviour but not cognitive flexibility in adolescent autism spectrum disorder.

PubMed

Wolff, Nicole; Chmielewski, Witold X; Beste, Christian; Roessner, Veit

2017-03-16

Autism spectrum disorder (ASD) is associated with repetitive and stereotyped behaviour, suggesting that cognitive flexibility may be deficient in ASD. A central, yet not examined aspect to understand possible deficits in flexible behaviour in ASD relates (i) to the role of working memory and (ii) to neurophysiological mechanisms underlying behavioural modulations. We analysed behavioural and neurophysiological (EEG) correlates of cognitive flexibility using a task-switching paradigm with and without working memory load in adolescents with ASD and typically developing controls (TD). Adolescents with ASD versus TD show similar performance in task switching with no memory load, indicating that 'pure' cognitive flexibility is not in deficit in adolescent ASD. However performance during task repetition decreases with increasing memory load. Neurophysiological data reflect the pattern of behavioural effects, showing modulations in P2 and P3 event-related potentials. Working memory demands affect repetitive behaviour while processes of cognitive flexibility are unaffected. Effects emerge due to deficits in preparatory attentional processes and deficits in task rule activation, organisation and implementation of task sets when repetitive behaviour is concerned. It may be speculated that the habitual response mode in ASD (i.e. repetitive behaviour) is particularly vulnerable to additional demands on executive control processes.

Prevalence of common chronic pain in Hong Kong adults.

PubMed

Ng, Kwok Fu Jacobus; Tsui, Siu Lun; Chan, Wing Sang

2002-01-01

Chronic pain is prevalent in many Western countries. Its prevalence in a non-Caucasian population is not known. The authors performed this study to measure the prevalence of chronic pain in the Hong Kong Chinese adult population, as well as the pattern of pain and the demographic characteristics, the impact on social and work function, and the help-seeking behavior of those with pain. Cross-sectional survey using telephone interview with a structured questionnaire. Chronic pain was defined as pain persisting for more than 3 months. A random sample of over 1,000 persons out of the entire Chinese adult population of Hong Kong. One thousand fifty-one adults were interviewed. One hundred thirteen (10.8% [95% C.I.: 8.9%-12.7%]) had chronic pain. The median number of pains was two. Of those with chronic pain, 38.3% reported their work was affected, and 19.8% had taken a median of 5 days' sick leave in the past year; 70.8% said the pain had interfered with their daily life, 88.5% had tried self-treatment, and 74.3% had sought medical advice. Only 35.7% considered the treatment definitely helpful. Two risk factors were identified: the female gender (O.R. 1.5, 95% C.I. 1.0-2.3) and age greater than 60 (O.R. 2.2, 95% C.I. 1.3-3.6). The study showed that the prevalence of chronic pain in Hong Kong adults was approximately 10.8%. Work and daily life are significantly affected and there is considerable demand on the health care system. Despite the ethnic difference, the prevalence, pattern, and demographic characteristics of chronic pain in Hong Kong are very similar to those seen in Western countries.

Micropatterned Azopolymer Surfaces Modulate Cell Mechanics and Cytoskeleton Structure.

PubMed

Rianna, Carmela; Ventre, Maurizio; Cavalli, Silvia; Radmacher, Manfred; Netti, Paolo A

2015-09-30

Physical and chemical characteristics of materials are important regulators of cell behavior. In particular, cell elasticity is a fundamental parameter that reflects the state of a cell. Surface topography finely modulates cell fate and function via adhesion mediated signaling and cytoskeleton generated forces. However, how topographies alter cell mechanics is still unclear. In this work we have analyzed the mechanical properties of peripheral and nuclear regions of NIH-3T3 cells on azopolymer substrates with different topographic patterns. Micrometer scale patterns in the form of parallel ridges or square lattices of surface elevations were encoded on light responsive azopolymer films by means of contactless optical methods. Cell mechanics was investigated by atomic force microscopy (AFM). Cells and consequently the cell cytoskeleton were oriented along the linear patterns affecting cytoskeletal structures, e.g., formation of actin stress fibers. Our data demonstrate that topographic substrate patterns are recognized by cells and mechanical information is transferred by the cytoskeleton. Furthermore, cytoskeleton generated forces deform the nucleus, changing its morphology that appears to be related to different mechanical properties in the nuclear region.

Alternative Work Patterns as Innovations in the Work Place. Overview: ERIC Fact Sheet No. 19.

ERIC Educational Resources Information Center

Denniston, Denie

Alternative work patterns are work schedules that allow employees to select the hours and length of their workweeks. Reasons for choosing alternative work patterns include transportation considerations, participation in outside activities, ability to work better during certain hours, child care, and household commitments. Examples of alternative…

Association between patterns of maternal substance use and infant birth weight, length, and head circumference.

PubMed

Shankaran, Seetha; Das, Abhik; Bauer, Charles R; Bada, Henrietta S; Lester, Barry; Wright, Linda L; Smeriglio, Vincent

2004-08-01

To determine the effects of patterns of drug use during term pregnancy on infant growth parameters at birth. Histories of cocaine, opiate, alcohol, tobacco, and marijuana use during the 3-month period before pregnancy and the 3 trimesters of pregnancy were recorded at the infants' 1-month visit. Patterns of use were categorized as consistently high, moderate, or low/none or increasing/decreasing, and effects on growth parameters were analyzed in multivariate linear regression analyses, with adjustment for clinical site, maternal age, prepregnancy weight, multidrug use, and socioeconomic status. A total of 241 cocaine-exposed women and 410 non-cocaine-exposed women participated in the study. In the cocaine-exposed group, 75% used alcohol, 90% used tobacco, and 53% used marijuana; in the non-cocaine-exposed group, 57% used alcohol, 34% used tobacco, and 19% used marijuana. Birth weight, birth length, and head circumference were significantly greater among infants born to women who used no drugs, compared with women with any cocaine, opiate, alcohol, tobacco, or marijuana use, and were greater among infants born to cocaine nonusers, compared with cocaine users. With adjustment for confounders, birth weight was significantly affected by cocaine (deficit of 250 g with consistently low pattern) and tobacco (deficits of 232 g with consistently high pattern, 173 g with consistently moderate pattern, 153 g with decreasing pattern, and 103 g with consistently low pattern). Head size was affected by cocaine (deficit of 0.98 cm with consistently moderate pattern) and tobacco (deficits of 0.72 cm with consistently high pattern and 0.89 cm with consistently moderate pattern). Birth length was affected by tobacco use only (deficits of 0.82 cm with consistently high pattern and 0.98 cm with decreasing use). Patterns of tobacco use during pregnancy affect birth weight, length, and head circumference, whereas cocaine affects birth weight and head size, when adjustments are made for confounders, including multidrug use.

Neonatal transection of the corpus callosum affects paw preference lateralization of adult Swiss mice.

PubMed

Manhães, Alex C; Krahe, Thomas E; Caparelli-Dáquer, Egas; Ribeiro-Carvalho, Anderson; Schmidt, Sergio L; Filgueiras, Cláudio C

2003-09-11

In the present work, the hypothesis that the ontogenetic development of the corpus callosum (CC) affects the establishment of behavioral lateralization was tested by studying paw preference performance in adult Swiss mice that were subjected to mid-sagittal transection of the CC on the first postnatal day. Magnitude and direction of laterality were evaluated independently. No significant differences between groups were found for the magnitude of paw preference. On the other hand, the transected group presented a significant populational bias favoring the left paw that was not present in the control groups. These results lend support to the hypothesis that the development of the CC plays a role in the establishment of the normal pattern of behavioral lateralization.

The epigenomic landscape of African rainforest hunter-gatherers and farmers.

PubMed

Fagny, Maud; Patin, Etienne; MacIsaac, Julia L; Rotival, Maxime; Flutre, Timothée; Jones, Meaghan J; Siddle, Katherine J; Quach, Hélène; Harmant, Christine; McEwen, Lisa M; Froment, Alain; Heyer, Evelyne; Gessain, Antoine; Betsem, Edouard; Mouguiama-Daouda, Patrick; Hombert, Jean-Marie; Perry, George H; Barreiro, Luis B; Kobor, Michael S; Quintana-Murci, Lluis

2015-11-30

The genetic history of African populations is increasingly well documented, yet their patterns of epigenomic variation remain uncharacterized. Moreover, the relative impacts of DNA sequence variation and temporal changes in lifestyle and habitat on the human epigenome remain unknown. Here we generate genome-wide genotype and DNA methylation profiles for 362 rainforest hunter-gatherers and sedentary farmers. We find that the current habitat and historical lifestyle of a population have similarly critical impacts on the methylome, but the biological functions affected strongly differ. Specifically, methylation variation associated with recent changes in habitat mostly concerns immune and cellular functions, whereas that associated with historical lifestyle affects developmental processes. Furthermore, methylation variation--particularly that correlated with historical lifestyle--shows strong associations with nearby genetic variants that, moreover, are enriched in signals of natural selection. Our work provides new insight into the genetic and environmental factors affecting the epigenomic landscape of human populations over time.

Development of a templated approach to fabricate diamond patterns on various substrates.

PubMed

Shimoni, Olga; Cervenka, Jiri; Karle, Timothy J; Fox, Kate; Gibson, Brant C; Tomljenovic-Hanic, Snjezana; Greentree, Andrew D; Prawer, Steven

2014-06-11

We demonstrate a robust templated approach to pattern thin films of chemical vapor deposited nanocrystalline diamond grown from monodispersed nanodiamond (mdND) seeds. The method works on a range of substrates, and we herein demonstrate the method using silicon, aluminum nitride (AlN), and sapphire substrates. Patterns are defined using photo- and e-beam lithography, which are seeded with mdND colloids and subsequently introduced into microwave assisted chemical vapor deposition reactor to grow patterned nanocrystalline diamond films. In this study, we investigate various factors that affect the selective seeding of different substrates to create high quality diamond thin films, including mdND surface termination, zeta potential, surface treatment, and plasma cleaning. Although the electrostatic interaction between mdND colloids and substrates is the main process driving adherence, we found that chemical reaction (esterification) or hydrogen bonding can potentially dominate the seeding process. Leveraging the knowledge on these different interactions, we optimize fabrication protocols to eliminate unwanted diamond nucleation outside the patterned areas. Furthermore, we have achieved the deposition of patterned diamond films and arrays over a range of feature sizes. This study contributes to a comprehensive understanding of the mdND-substrate interaction that will enable the fabrication of integrated nanocrystalline diamond thin films for microelectronics, sensors, and tissue culturing applications.

The numerical model of multi-layer insulation with a defined wrapping pattern immersed in superfluid helium

NASA Astrophysics Data System (ADS)

Malecha, Ziemowit; Lubryka, Eliza

2017-11-01

The numerical model of thin layers, characterized by a defined wrapping pattern can be a crucial element of many computational problems related to engineering and science. A motivating example is found in multilayer electrical insulation, which is an important component of superconducting magnets and other cryogenic installations. The wrapping pattern of the insulation can significantly affect heat transport and the performance of the considered instruments. The major objective of this study is to develop the numerical boundary conditions (BC) needed to model the wrapping pattern of thin insulation. An example of the practical application of the proposed BC includes the heat transfer of Rutherford NbTi cables immersed in super-fluid helium (He II) across thin layers of electrical insulation. The proposed BC and a mathematical model of heat transfer in He II are implemented in the open source CFD toolbox OpenFOAM. The implemented mathematical model and the BC are compared in the experiments. The study confirms that the thermal resistance of electrical insulation can be lowered by implementing the proper wrapping pattern. The proposed BC can be useful in the study of new patterns for wrapping schemes. The work has been supported by statutory funds from Polish Ministry for Science and Higher Education for the year of 2017.

[Variables related to the emergence of differential patterns in work motivation].

PubMed

Arrieta, Carlos; Navarro, José; Vicente, Susana

2008-11-01

Several longitudinal studies have shown that motivation at work acts chaotically. In very few cases, it may be linear or random. However, the factors that might explain why these different patterns emerge have not been analysed to date. In this exploratory study, we interviewed 73 employees whose motivational patterns were previously known. The results revealed that chaotic patterns were associated with high levels of motivation, self-efficacy beliefs, and perceptions of instrumentality, and also with intrinsic personal goal orientation and a perception of high work control. Linear patterns were associated with extrinsic goals and a perception of work as difficult, and random patterns were linked to high flexibility at work.

Spatial context learning survives interference from working memory load

PubMed Central

Vickery, Timothy J.; Sussman, Rachel S.; Jiang, Yuhong V.

2010-01-01

The human visual system is constantly confronted with an overwhelming amount of information, only a subset of which can be processed in complete detail. Attention and implicit learning are two important mechanisms that optimize vision. This study addresses the relationship between these two mechanisms. Specifically we ask: Is implicit learning of spatial context affected by the amount of working memory load devoted to an irrelevant task? We tested observers in visual search tasks where search displays occasionally repeated. Observers became faster searching repeated displays than unrepeated ones, showing contextual cueing. We found that the size of contextual cueing was unaffected by whether observers learned repeated displays under unitary attention or when their attention was divided using working memory manipulations. These results held when working memory was loaded by colors, dot patterns, individual dot locations, or multiple potential targets. We conclude that spatial context learning is robust to interference from manipulations that limit the availability of attention and working memory. PMID:20853996

The social and economic context and determinants of schistosomiasis japonica.

PubMed

Huang, Yi-Xin; Manderson, Lenore

2005-01-01

A variety of biological and social factors govern schistosomiasis japonica in China. Social factors include those at a national and regional level, such as policies and patterns of development, which impact on local economic activities, and affect community, household and personal risk factors of infection. Drawing on research conducted in China, we illustrate how social structural and related factors influence individual risk and prevalence of infection. At a macro-level, political changes have occurred resulting in the shift from collective to family-based production, leading to clustering of infection in families. Industrialization and urbanization, and associated increased population mobility, have also influenced patterns of transmission and infection. Types of activities and local production patterns determine the exposure of individuals to schistosome-infested water sources. Fishermen have the most frequent water contact, aquatic workers the second and farmers the third; the relative risk of Schistosoma japonicum infection follows the same order. Among farmers, human infection is significantly related to agricultural production in rice fields infested with the intermediate host snail, and to rates of the infection in livestock. Risk of S. japonicum infection is also influenced by the domestic environment, including both the location of the house in relation to snail-colonized water sources, access to safe water, and improved sanitation. Household wealth and income determine family ability to provide and maintain safe water and sanitation, while determining or interacting with other variables. At an individual level, sex, age, educational level and ethnicity are all associated with different patterns of water use and water contact behaviour thereby affecting infection rates. Schistosomiasis impairs the growth and nutrition of children and the physical work capacity of adults, and so affects economic development. Given this, we note the importance of further research and social and contextual aspects of schistosomiasis infection in order to develop and sustain sound control strategies.

Effects of hearing loss on speech recognition under distracting conditions and working memory in the elderly.

PubMed

Na, Wondo; Kim, Gibbeum; Kim, Gungu; Han, Woojae; Kim, Jinsook

2017-01-01

The current study aimed to evaluate hearing-related changes in terms of speech-in-noise processing, fast-rate speech processing, and working memory; and to identify which of these three factors is significantly affected by age-related hearing loss. One hundred subjects aged 65-84 years participated in the study. They were classified into four groups ranging from normal hearing to moderate-to-severe hearing loss. All the participants were tested for speech perception in quiet and noisy conditions and for speech perception with time alteration in quiet conditions. Forward- and backward-digit span tests were also conducted to measure the participants' working memory. 1) As the level of background noise increased, speech perception scores systematically decreased in all the groups. This pattern was more noticeable in the three hearing-impaired groups than in the normal hearing group. 2) As the speech rate increased faster, speech perception scores decreased. A significant interaction was found between speed of speech and hearing loss. In particular, 30% of compressed sentences revealed a clear differentiation between moderate hearing loss and moderate-to-severe hearing loss. 3) Although all the groups showed a longer span on the forward-digit span test than the backward-digit span test, there was no significant difference as a function of hearing loss. The degree of hearing loss strongly affects the speech recognition of babble-masked and time-compressed speech in the elderly but does not affect the working memory. We expect these results to be applied to appropriate rehabilitation strategies for hearing-impaired elderly who experience difficulty in communication.

Patterning of polymer nanofiber meshes by electrospinning for biomedical applications

PubMed Central

Neves, Nuno M; Campos, Rui; Pedro, Adriano; Cunha, José; Macedo, Francisco; Reis, Rui L

2007-01-01

The end-product of the electrospinning process is typically a randomly aligned fiber mesh or membrane. This is a result of the electric field generated between the drop of polymer solution at the needle and the collector. The developed electric field causes the stretching of the fibers and their random deposition. By judicious selection of the collector architecture, it is thus possible to develop other morphologies on the nanofiber meshes. The aim of this work is to prepare fiber meshes using various patterned collectors with specific dimensions and designs and to evaluate how those patterns can affect the properties of the meshes relevant to biomedical applications. This study aims at verifying whether it is possible to control the architecture of the fiber meshes by tailoring the geometry of the collector. Three different metallic collector topographies are used to test this hypothesis. Electrospun nonwoven patterned meshes of polyethylene oxide (PEO) and poly(ε-capro-lactone) (PCL) were successfully prepared. Those fiber meshes were analyzed by scanning electron microscopy (SEM). Both mechanical properties of the meshes and cell contacting experiments were performed to test the effect of the produced patterns over the properties of the meshes relevant for biomedical applications. The present study will evaluate cell adhesion sensitivity to the patterns generated and the effect of those patterns on the tensile properties of the fiber meshes. PMID:18019842

Comparison of Two Parametric Methods to Estimate Pesticide Mass Loads in California's Central Valley

USGS Publications Warehouse

Saleh, D.K.; Lorenz, D.L.; Domagalski, Joseph L.

2011-01-01

Mass loadings were calculated for four pesticides in two watersheds with different land uses in the Central Valley, California, by using two parametric models: (1) the Seasonal Wave model (SeaWave), in which a pulse signal is used to describe the annual cycle of pesticide occurrence in a stream, and (2) the Sine Wave model, in which first-order Fourier series sine and cosine terms are used to simulate seasonal mass loading patterns. The models were applied to data collected during water years 1997 through 2005. The pesticides modeled were carbaryl, diazinon, metolachlor, and molinate. Results from the two models show that the ability to capture seasonal variations in pesticide concentrations was affected by pesticide use patterns and the methods by which pesticides are transported to streams. Estimated seasonal loads compared well with results from previous studies for both models. Loads estimated by the two models did not differ significantly from each other, with the exceptions of carbaryl and molinate during the precipitation season, where loads were affected by application patterns and rainfall. However, in watersheds with variable and intermittent pesticide applications, the SeaWave model is more suitable for use on the basis of its robust capability of describing seasonal variation of pesticide concentrations. ?? 2010 American Water Resources Association. This article is a US Government work and is in the public domain in the USA.

Is Long-Term Structural Priming Affected by Patterns of Experience with Individual Verbs?

ERIC Educational Resources Information Center

Kaschak, Michael P.; Borreggine, Kristin L.

2008-01-01

Several recent papers have reported long-term structural priming effects in experiments where previous patterns of experience with the double object and prepositional object constructions are shown to affect later patterns of language production for those constructions. The experiments reported in this paper address the extent to which these…

Distinct aggregation patterns and fluid porous phase in a 2D model for colloids with competitive interactions

NASA Astrophysics Data System (ADS)

Bordin, José Rafael

2018-04-01

In this paper we explore the self-assembly patterns in a two dimensional colloidal system using extensive Langevin Dynamics simulations. The pair potential proposed to model the competitive interaction have a short range length scale between first neighbors and a second characteristic length scale between third neighbors. We investigate how the temperature and colloidal density will affect the assembled morphologies. The potential shows aggregate patterns similar to observed in previous works, as clusters, stripes and porous phase. Nevertheless, we observe at high densities and temperatures a porous mesophase with a high mobility, which we name fluid porous phase, while at lower temperatures the porous structure is rigid. triangular packing was observed for the colloids and pores in both solid and fluid porous phases. Our results show that the porous structure is well defined for a large range of temperature and density, and that the fluid porous phase is a consequence of the competitive interaction and the random forces from the Langevin Dynamics.

Structure preserving clustering-object tracking via subgroup motion pattern segmentation

NASA Astrophysics Data System (ADS)

Fan, Zheyi; Zhu, Yixuan; Jiang, Jiao; Weng, Shuqin; Liu, Zhiwen

2018-01-01

Tracking clustering objects with similar appearances simultaneously in collective scenes is a challenging task in the field of collective motion analysis. Recent work on clustering-object tracking often suffers from poor tracking accuracy and terrible real-time performance due to the neglect or the misjudgment of the motion differences among objects. To address this problem, we propose a subgroup motion pattern segmentation framework based on a multilayer clustering structure and establish spatial constraints only among objects in the same subgroup, which entails having consistent motion direction and close spatial position. In addition, the subgroup segmentation results are updated dynamically because crowd motion patterns are changeable and affected by objects' destinations and scene structures. The spatial structure information combined with the appearance similarity information is used in the structure preserving object tracking framework to track objects. Extensive experiments conducted on several datasets containing multiple real-world crowd scenes validate the accuracy and the robustness of the presented algorithm for tracking objects in collective scenes.

Polymer adsorption-driven self-assembly of nanostructures.

PubMed

Chakraborty, A K; Golumbfskie, A J

2001-01-01

Driven by prospective applications, there is much interest in developing materials that can perform specific functions in response to external conditions. One way to design such materials is to create systems which, in response to external inputs, can self-assemble to form structures that are functionally useful. This review focuses on the principles that can be employed to design macromolecules that when presented with an appropriate two-dimensional surface, will self-assemble to form nanostructures that may be functionally useful. We discuss three specific examples: (a) biomimetic recognition between polymers and patterned surfaces. (b) control and manipulation of nanomechanical motion generated by biopolymer adsorption and binding, and (c) creation of patterned nanostructuctures by exposing molten diblock copolymers to patterned surfaces. The discussion serves to illustrate how polymer sequence can be manipulated to affect self-assembly characteristics near adsorbing surfaces. The focus of this review is on theoretical and computational work aimed toward elucidating the principles underlying the phenomena pertinent to the three topics noted above. However, synergistic experiments are also described in the appropriate context.

Ultrastructure of the surface of dental enamel with molar incisor hypomineralization (MIH) with and without acid etching.

PubMed

Bozal, Carola B; Kaplan, Andrea; Ortolani, Andrea; Cortese, Silvina G; Biondi, Ana M

2015-01-01

The aim of the present work was to analyze the ultrastructure and mineral composition of the surface of the enamel on a molar with MIH, with and without acid etching. A permanent tooth without clinical MIH lesions (control) and a tooth with clinical diagnosis of mild and moderate MIH, with indication for extraction, were processed with and without acid etching (H3PO4 37%, 20") for observation with scanning electron microscope (SEM) ZEISS (Supra 40) and mineral composition analysis with an EDS detector (Oxford Instruments). The control enamel showed normal prismatic surface and etching pattern. The clinically healthy enamel on the tooth with MIH revealed partial loss of prismatic pattern. The mild lesion was porous with occasional cracks. The moderate lesion was more porous, with larger cracks and many scales. The mineral composition of the affected surfaces had lower Ca and P content and higher O and C. On the tooth with MIH, even on normal looking enamel, the demineralization does not correspond to an etching pattern, and exhibits exposure of crystals with rods with rounded ends and less demineralization in the inter-prismatic spaces. Acid etching increased the presence of cracks and deep pores in the adamantine structure of the enamel with lesion. In moderate lesions, the mineral composition had higher content of Ca, P and Cl. Enamel with MIH, even on clinically intact adamantine surfaces, shows severe alterations in the ultrastructure and changes in ionic composition, which affect the acid etching pattern and may interfere with adhesion.

Navigation Patterns and Scent Marking: Underappreciated Contributors to Hippocampal and Entorhinal Spatial Representations?

PubMed

Lebedev, Mikhail A; Pimashkin, Alexey; Ossadtchi, Alexei

2018-01-01

According to the currently prevailing theory, hippocampal formation constructs and maintains cognitive spatial maps. Most of the experimental evidence for this theory comes from the studies on navigation in laboratory rats and mice, typically male animals. While these animals exhibit a rich repertoire of behaviors associated with navigation, including locomotion, head movements, whisking, sniffing, raring and scent marking, the contribution of these behavioral patterns to the hippocampal spatially-selective activity has not been sufficiently studied. Instead, many publications have considered animal position in space as the major variable that affects the firing of hippocampal place cells and entorhinal grid cells. Here we argue that future work should focus on a more detailed examination of different behaviors exhibited during navigation to better understand the mechanism of spatial tuning in hippocampal neurons. As an inquiry in this direction, we have analyzed data from two datasets, shared online, containing recordings from rats navigating in square and round arenas. Our analyses revealed patchy navigation patterns, evident from the spatial maps of animal position, velocity and acceleration. Moreover, grid cells available in the datasets exhibited similar periodicity as the navigation parameters. These findings indicate that activity of grid cells could affect navigation parameters and/or vice versa. Additionally, we speculate that scent marks left by navigating animals could contribute to neuronal responses while rats and mice sniff their environment; the act of sniffing could modulate neuronal discharges even in virtual visual environments. Accordingly, we propose that future experiments should contain additional controls for navigation patterns, whisking, sniffing and maps composed of scent marks.

The influence of trait-negative affect and compassion satisfaction on compassion fatigue in Australian nurses.

PubMed

Craigie, Mark; Osseiran-Moisson, Rebecca; Hemsworth, David; Aoun, Samar; Francis, Karen; Brown, Janie; Hegney, Desley; Rees, Clare

2016-01-01

For this study, we examined the nature of the unique relationships trait-negative affect and compassion satisfaction had with compassion fatigue and its components of secondary traumatic stress and burnout in 273 nurses from 1 metropolitan tertiary acute hospital in Western Australia. Participants completed the Professional Quality of Life Scale (Stamm, 2010), Depression Anxiety Stress Scale (Lovibond & Lovibond, 2004), and the State-Trait Anxiety Inventory (Spielberger, Gorsuch, Lushene, Vagg, & Jacobs, 1983). Bivariate correlation and hierarchical regression analyses were performed to examine and investigate 4 hypotheses. The results demonstrate a clear differential pattern of relationships with secondary traumatic stress and burnout for both trait-negative affect and compassion satisfaction. Trait-negative affect was clearly the more important factor in terms of its contribution to overall compassion fatigue and secondary traumatic stress. In contrast, compassion satisfaction's unique protective relationship only related to burnout, and not secondary traumatic stress. The results are therefore consistent with the view that compassion satisfaction may be an important internal resource that protects against burnout, but is not directly influential in protecting against secondary traumatic stress for nurses working in an acute-care hospital environment. With the projected nursing workforce shortages in Australia, it is apparent that a further understanding is warranted of how such personal variables may work as protective and risk factors. (c) 2016 APA, all rights reserved).

Spatiotemporal patterns of population distribution as crucial element for risk management

NASA Astrophysics Data System (ADS)

Gokesch, Karin; Promper, Catrin; van Westen, Cees J.; Glade, Thomas

2014-05-01

The spatiotemporal distribution and presence of the population in a certain area is a crucial element within natural hazard risk management, especially in the case of rapid onset hazard events and emergency management. When fast onset hazards such as earthquakes, flash floods or industrial accidents occur, people may not have adequate time for evacuation and the emergency management requires a fast response and reaction. Therefore, information on detailed distribution of people affected by a certain hazard is important for a fast assessment of the situation including the number and the type of people (distinguishing between elderly or handicapped people, children, working population etc.) affected. This study thus aims at analyzing population distribution on an hourly basis for different days e.g. workday or holiday. The applied method combines the basic assessment of population distribution in a given area with specific location-related patterns of distribution-changes over time. The calculations are based on detailed information regarding the expected presence of certain groups of people, e.g. school children, working or elderly people, which all show different patterns of movement over certain time periods. The study area is the city of Waidhofen /Ybbs located in the Alpine foreland in the Southwest of Lower Austria. This city serves as a regional center providing basic infrastructure, shops and schools for the surrounding countryside. Therefore a lot of small and medium businesses are located in this area showing a rather high variation of population present at different times of the day. The available building footprint information was classified with respect to building type and occupancy type, which was used to estimate the expected residents within the buildings, based on the floorspace of the buildings and the average floorspace per person. Additional information on the distribution and the average duration of stay of the people in these buildings was assessed using general population statistics and specific information about selected buildings, such as schools, hospitals or homes for the elderly, to calculate the distribution patterns for each group of people over time.

Thank goodness it's Friday: weekly pattern of workplace incivility.

PubMed

Nicholson, Tahnee; Griffin, Barbara

2017-01-01

Recent research has shown day-level differences in an individual's experience of uncivil behavior; however, it is unknown if that experience follows a consistent weekly change pattern. This study extends incivility theory and research by applying latent growth curve (LGC) modeling to diary study data to understand day-to-day changes in incivility. The authors took a theory-driven approach, reviewing both mood and recovery theory that would support a decrease in incivility over the working week. Diary survey methodology was used, with a morning and evening survey completed on five consecutive workdays by 171 (73% of the 235 who initially volunteered, 95% of those who completed any surveys) employees in the legal industry. LGC analysis was used to identify patterns of experienced incivility, mood (both measured after work), and recovery (assessed the following morning). Regardless of job demands and gender, a weekly pattern was identified with the likelihood of experiencing incivility (coded as 0 = none, 1 = some) decreasing from Monday to Friday by .78 each day (p < .001) in a relatively linear fashion with a slope factor of .34 (SE = 0.23; p > .05), indicating invariance between individuals. This weekly pattern was not explained by changes in mood or recovery. Results emphasize the impact of contextual factors such as time on workplace incivility and the need to consider weekly rhythms of other behaviors that are likely to affect employee well-being and productivity. Although limited to one week of data per person, the findings are likely to be relevant to studies of other forms of interpersonal mistreatment, such as social undermining and interpersonal conflict.

Numerical investigation of aggregated fuel spatial pattern impacts on fire behavior

DOE PAGES

Parsons, Russell A.; Linn, Rodman Ray; Pimont, Francois; ...

2017-06-18

Here, landscape heterogeneity shapes species distributions, interactions, and fluctuations. Historically, in dry forest ecosystems, low canopy cover and heterogeneous fuel patterns often moderated disturbances like fire. Over the last century, however, increases in canopy cover and more homogeneous patterns have contributed to altered fire regimes with higher fire severity. Fire management strategies emphasize increasing within-stand heterogeneity with aggregated fuel patterns to alter potential fire behavior. Yet, little is known about how such patterns may affect fire behavior, or how sensitive fire behavior changes from fuel patterns are to winds and canopy cover. Here, we used a physics-based fire behavior model,more » FIRETEC, to explore the impacts of spatially aggregated fuel patterns on the mean and variability of stand-level fire behavior, and to test sensitivity of these effects to wind and canopy cover. Qualitative and quantitative approaches suggest that spatial fuel patterns can significantly affect fire behavior. Based on our results we propose three hypotheses: (1) aggregated spatial fuel patterns primarily affect fire behavior by increasing variability; (2) this variability should increase with spatial scale of aggregation; and (3) fire behavior sensitivity to spatial pattern effects should be more pronounced under moderate wind and fuel conditions.« less

Numerical investigation of aggregated fuel spatial pattern impacts on fire behavior

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parsons, Russell A.; Linn, Rodman Ray; Pimont, Francois

Here, landscape heterogeneity shapes species distributions, interactions, and fluctuations. Historically, in dry forest ecosystems, low canopy cover and heterogeneous fuel patterns often moderated disturbances like fire. Over the last century, however, increases in canopy cover and more homogeneous patterns have contributed to altered fire regimes with higher fire severity. Fire management strategies emphasize increasing within-stand heterogeneity with aggregated fuel patterns to alter potential fire behavior. Yet, little is known about how such patterns may affect fire behavior, or how sensitive fire behavior changes from fuel patterns are to winds and canopy cover. Here, we used a physics-based fire behavior model,more » FIRETEC, to explore the impacts of spatially aggregated fuel patterns on the mean and variability of stand-level fire behavior, and to test sensitivity of these effects to wind and canopy cover. Qualitative and quantitative approaches suggest that spatial fuel patterns can significantly affect fire behavior. Based on our results we propose three hypotheses: (1) aggregated spatial fuel patterns primarily affect fire behavior by increasing variability; (2) this variability should increase with spatial scale of aggregation; and (3) fire behavior sensitivity to spatial pattern effects should be more pronounced under moderate wind and fuel conditions.« less

Electrostatic complementarity between proteins and ligands. 1. Charge disposition, dielectric and interface effects

NASA Astrophysics Data System (ADS)

Chau, P.-L.; Dean, P. M.

1994-10-01

Electrostatic interactions have always been considered an important factor governing ligand-receptor interactions. Previous work in this field has established the existence of electrostatic complementarity between the ligand and its receptor site. However, this property has not been treated rigorously, and the description remains largely qualitative. In this work, 34 data sets of high quality were chosen from the Brookhaven Protein Databank. The electrostatic complementarity has been calculated between the surface potentials; complementarity is absent between adjacent or neighbouring atoms of the ligand and the receptor. There is little difference between complementarities on the total ligand surface and the interfacial region. Altering the homogeneous dielectric to distance-dependent dielectrics reduces the complementarity slightly, but does not affect the pattern of complementarity.

Electrostatic complementarity between proteins and ligands. 1. Charge disposition, dielectric and interface effects.

PubMed

Chau, P L; Dean, P M

1994-10-01

Electrostatic interactions have always been considered an important factor governing ligand-receptor interactions. Previous work in this field has established the existence of electrostatic complementarity between the ligand and its receptor site. However, this property has not been treated rigorously, and the description remains largely qualitative. In this work, 34 data sets of high quality were chosen from the Brookhaven Protein Databank. The electrostatic complementary has been calculated between the surface potentials; complementarity is absent between adjacent or neighbouring atoms of the ligand and the receptor. There is little difference between complementarities on the total ligand surface and the interfacial region. Altering the homogeneous dielectric to distance-dependent dielectrics reduces the complementarity slightly, but does not affect the pattern of complementarity.

Some effects of time usage patterns on the productivity of engineers

NASA Technical Reports Server (NTRS)

Jackson, Conrad N.

1992-01-01

The performance of the 1500+ engineers at MSFC is critical to the Center's mission. Worker's performance, however, is a variable affected by ability, motivation, role understanding, and other factors. Managing subordinates' performance is a great challenges to managers. Special challenges confront the managers of engineers because engineers often work with general goals, long deadlines, and considerable autonomy. The productivity of a team or branch is a function of the productivity of each of its members. While many managers have personal theories about how to run their work group, surprisingly little systematic scientific knowledge exerts about the effects of various factors on engineers' productivity. This study is intended to help lay the foundation for such a program of research.

Critical thinking: Reported enhancers and barriers by nurses in long-term care: implications for staff development.

PubMed

Raterink, Ginger

2011-01-01

Nursing acknowledges critical thinking as an important guide to clinical decision making. Agreement on how to define, teach, and evaluate this skill is lacking. The purpose of this study was to evaluate critical thinking in practice using a survey that asked nurses to evaluate work-related factors that enhance or pose barriers to the use of critical thinking in practice. Results indicated that enhancers and barriers to practice included teamwork, staffing patterns, and staff and administrator support. A relationship with patients was the most satisfying factor, whereas paperwork was the least. Staff development educators must consider the work environment aspects that affect performance and create the life long learning needed for increased competency in practice.

SABRE is required for stabilization of root hair patterning in Arabidopsis thaliana.

PubMed

Pietra, Stefano; Lang, Patricia; Grebe, Markus

2015-03-01

Patterned differentiation of distinct cell types is essential for the development of multicellular organisms. The root epidermis of Arabidopsis thaliana is composed of alternating files of root hair and non-hair cells and represents a model system for studying the control of cell-fate acquisition. Epidermal cell fate is regulated by a network of genes that translate positional information from the underlying cortical cell layer into a specific pattern of differentiated cells. While much is known about the genes of this network, new players continue to be discovered. Here we show that the SABRE (SAB) gene, known to mediate microtubule organization, anisotropic cell growth and planar polarity, has an effect on root epidermal hair cell patterning. Loss of SAB function results in ectopic root hair formation and destabilizes the expression of cell fate and differentiation markers in the root epidermis, including expression of the WEREWOLF (WER) and GLABRA2 (GL2) genes. Double mutant analysis reveal that wer and caprice (cpc) mutants, defective in core components of the epidermal patterning pathway, genetically interact with sab. This suggests that SAB may act on epidermal patterning upstream of WER and CPC. Hence, we provide evidence for a role of SAB in root epidermal patterning by affecting cell-fate stabilization. Our work opens the door for future studies addressing SAB-dependent functions of the cytoskeleton during root epidermal patterning. © 2014 The Authors. Physiologia Plantarum published by John Wiley & Sons Ltd on behalf of Scandinavian Plant Physiology Society.

Trends in dental and allied dental education.

PubMed

Neumann, Laura M

2004-09-01

Educational programs play an important role in preparing a qualified dental work force. This article reviews the current status and trends in dental, advanced dental and allied dental education programs in the United States and examines their impact on the dental work force. This analysis focuses on survey data collected by the American Dental Association during the past 10 to 15 years and compares recent patterns in applications, enrollment and graduation with previous trends. The numbers of educational programs, applicants, enrollees and graduates have increased in dentistry, dental hygiene and dental assisting, while dental laboratory technology has declined in all measures. The proportion of women in dentistry has increased, while the ethnic profile of dental and allied personnel has shown little change. Both the cost of dental education and student debt continue to increase. Despite increases in the number of educational programs and overall numbers of graduates from dental and allied dental education programs, the proportion of underrepresented groups still lags behind their representation in the overall population, and the number of allied personnel falls short of practice needs. Patterns in applications, enrollment and graduation are important determinants of the dental and allied dental work force. The cost and funding of education significantly affect the attractiveness of dental careers and the sustainability of educational programs and should be monitored carefully by the profession.

Shift work--problems and its impact on female nurses in Udaipur, Rajasthan India.

PubMed

Rathore, H; Shukla, K; Singh, S; Tiwari, G

2012-01-01

Abstract : There is good evidence that shift work has negative effects on workers health, safety and performance. It is quite appropriate that attention is paid to this very important feature of socio-technical systems, which may adversely affect mental and physical health, social life and safety of shift workers. Research into the impact of shift work on professionals has consistently identified a range of negative outcomes in physical, psychological, and social domains (Akerstedt, 1988; Costa, Lievore, Casaletti, Gaffuri, & Folkard, 1989; Kogi, 2005; Paley & Tepas, 1994). Hospitals, the biggest employer in the health care field, employ more night shift workers than any other industry. It can therefore be inferred that in medical domain high percentage of workforce may be affected by problems related to shift work. Thus the present study will provide knowledge base for the problems faced by the female nurses. The present study was undertaken with an objective of getting an insight into the problems faced by female nurses in shift work. . It was found that the female nurses in India worked on roaster pattern of change in shift every seven days. They did not have a say in the change of duties, it could only be done on mutual grounds. Partners of younger group did not much adjust to their shift pattern this created stress among the nurses.The results showed that the female nurses in both the age groups i.e. 30-45 years and 45-60 years faced many problems related to health and well being, fatigue, social and domestic situations. They could not give much time to their children in particular. Travelling in nights was risky for them. Common problem was the insufficient sleep during night shifts. The nurses had to cater to the needs of the family, children in particular along with the adjustments to be made due to shift work. They had to sometimes do the night duties and attend social functions as a part of their duty. Children and husband in some cases did not cooperate this lead to frustration. When asked as to whether they would could shift job if they get regular one more than 50 % said yes this means that there need to be come training and intervention for the shift workers and their family so that the problems faced and their impact on personal health of the female nurses could be reduced.

Spatial Pattern of Soil Salinity in Area Around the Yellow River Delta and Its Seasonal Dynamics over a 3-year Period

NASA Astrophysics Data System (ADS)

Lai, J.; Ouyang, Z.

2017-12-01

Salt-affected land varies spatially and seasonally in terms of soil salinity. "Bohai Granary" is a newly proposed national-level program which was aimed to improve soil quality and mining grain production potential of the salt-affected land in east China. In this work, soil samples were monthly taken at 11 sites within Wudi county in the Yellow river delta. The spatial distribution pattern of soil salinity were investigated and its seasonal variation over 36 months were discussed. Our findings indicate that the vertical distribution type of soil salinity was bottom-accumulating in the near coastal area while its gradually turned into a type of surface-accumulating as the sampling site moving towards the inner land. The peak of the soil salinity along the soil profile alternately moved upwards and downwards during the growing seasons. However, there was no evidence for the increasing of the total salt amount within the upper 100cm of soil. Moreover, the salt was mostly accumulated in the upper soil (0-40cm) during the late spring and early summer season; and winter wheat was tend to be affected severely at this stage. Therefore, special field practices (e.g. regular irrigation to leach salt, good maintenance of drainage system) should be taken to minimize the threat of soil salinity.

Work-related behaviour and experience pattern in nurses: impact on physical and mental health.

PubMed

Schulz, M; Damkröger, A; Voltmer, E; Löwe, B; Driessen, M; Ward, M; Wingenfeld, K

2011-06-01

Nursing is associated with high levels of emotional strain and heavy workloads. Changing working conditions raise the importance of investigating job satisfaction, stress and burnout and its consequences for nurses. The aim of the study was to investigate whether work-related behaviour and experience patterns are associated with mental and physical health status in nurses. A sample of 356 nurses in four German hospitals were interviewed using questionnaires regarding work-related behaviour and experience patterns, work stress, depression, anxiety and physical symptoms ('Work-related Behaviour and Experience Pattern'--AVEM and ERI). The main result of this study is that unhealthy work-related behaviour and experience patterns (i.e. the excessive ambitious type and the resigned type) are associated with reduced mental and physical health. Preventive, as well as intervention, strategies are needed that focus both on the individual as well as on working conditions. © 2011 Blackwell Publishing.

Alternative Work Patterns: Implications for Worklife Education and Training. Worker Education and Training Policies Project.

ERIC Educational Resources Information Center

Shore, Jane

This monograph explores the major categories of alternative work patterns, e.g., flexitime, permanent part-time employment, job sharing, the compressed work week, and reduced work time. Advantages and disadvantages of each type are discussed, and new insight is offered into an unexplored dimension of the major types of alternative work patterns:…

Analysis of work zone rear-end crash risk for different vehicle-following patterns.

PubMed

Weng, Jinxian; Meng, Qiang; Yan, Xuedong

2014-11-01

This study evaluates rear-end crash risk associated with work zone operations for four different vehicle-following patterns: car-car, car-truck, truck-car and truck-truck. The deceleration rate to avoid the crash (DRAC) is adopted to measure work zone rear-end crash risk. Results show that the car-truck following pattern has the largest rear-end crash risk, followed by truck-truck, truck-car and car-car patterns. This implies that it is more likely for a car which is following a truck to be involved in a rear-end crash accident. The statistical test results further confirm that rear-end crash risk is statistically different between any two of the four patterns. We therefore develop a rear-end crash risk model for each vehicle-following pattern in order to examine the relationship between rear-end crash risk and its influencing factors, including lane position, the heavy vehicle percentage, lane traffic flow and work intensity which can be characterized by the number of lane reductions, the number of workers and the amount of equipment at the work zone site. The model results show that, for each pattern, there will be a greater rear-end crash risk in the following situations: (i) heavy work intensity; (ii) the lane adjacent to work zone; (iii) a higher proportion of heavy vehicles and (iv) greater traffic flow. However, the effects of these factors on rear-end crash risk are found to vary according to the vehicle-following patterns. Compared with the car-car pattern, lane position has less effect on rear-end crash risk in the car-truck pattern. The effect of work intensity on rear-end crash risk is also reduced in the truck-car pattern. Copyright © 2014 Elsevier Ltd. All rights reserved.

Cognitive status in patients with multiple sclerosis in Lanzarote.

PubMed

Pérez-Martín, María Yaiza; Eguia-Del Río, Pablo; González-Platas, Montserrat; Jiménez-Sosa, Alejandro

2016-01-01

Cognitive impairment is a common feature in multiple sclerosis affecting ~43%-72% of patients, which involves cognitive functions such as memory, processing speed, attention, and executive function. The aim of this study was to describe the extent and pattern of the involvement of cognitive impairment and psychological status in all patients with multiple sclerosis on a small Spanish island. In all, 70 patients and 56 healthy controls were included in the study between February 2013 and May 2013. All participants were assessed using the Brief Repeatable Battery of Neuropsychological Test. The patients also completed instruments to evaluate the presence of fatigue, perceived cognitive dysfunction, and symptoms of anxiety and depression. All procedures were performed in a single session. Cognitive impairment, defined as a score <1.5 standard deviation on two subtests of the battery, was present in 35% of the participants. The most frequently affected domain was working memory, followed by verbal memory and processing speed. Disease duration showed a moderate correlation with visuospatial memory and processing speed. The Expanded Disability Status Scale score correlated with verbal and processing speed. Verbal memory was correlated with depression symptoms and fatigue. Cognitive impairment was present in 35% of the study population. The most affected domains were working memory and verbal memory. Working memory and verbal fluency deficit are independent factors of disease evolution. Cognitive decline is related to clinical variables and psychological measures such as fatigue or depression but not to anxiety.

Cognitive status in patients with multiple sclerosis in Lanzarote

PubMed Central

Pérez-Martín, María Yaiza; Eguia-del Río, Pablo; González-Platas, Montserrat; Jiménez-Sosa, Alejandro

2016-01-01

Objectives Cognitive impairment is a common feature in multiple sclerosis affecting ~43%–72% of patients, which involves cognitive functions such as memory, processing speed, attention, and executive function. The aim of this study was to describe the extent and pattern of the involvement of cognitive impairment and psychological status in all patients with multiple sclerosis on a small Spanish island. Patients and methods In all, 70 patients and 56 healthy controls were included in the study between February 2013 and May 2013. All participants were assessed using the Brief Repeatable Battery of Neuropsychological Test. The patients also completed instruments to evaluate the presence of fatigue, perceived cognitive dysfunction, and symptoms of anxiety and depression. All procedures were performed in a single session. Results Cognitive impairment, defined as a score <1.5 standard deviation on two subtests of the battery, was present in 35% of the participants. The most frequently affected domain was working memory, followed by verbal memory and processing speed. Disease duration showed a moderate correlation with visuospatial memory and processing speed. The Expanded Disability Status Scale score correlated with verbal and processing speed. Verbal memory was correlated with depression symptoms and fatigue. Conclusion Cognitive impairment was present in 35% of the study population. The most affected domains were working memory and verbal memory. Working memory and verbal fluency deficit are independent factors of disease evolution. Cognitive decline is related to clinical variables and psychological measures such as fatigue or depression but not to anxiety. PMID:27418825

Status and Subscribing: A Response to Schwitzgebel

NASA Astrophysics Data System (ADS)

Hewson, Peter W.; Lemberger, John

Schwitzgebel (1999) has proposed an account of theories that can be used in deciding whether children's cognitive development is like theory change in science. In this article we outline an account of conceptual learning in terms of the conceptions that people hold, the status they award to their conceptions, and the conceptual ecology containing the criteria they use in determining status. A comparison of our account with Schwitzgebel's shows an equivalence between Schwitzgebel's subscribing and one component of status (fruitfulness), but no counterpart to another (plausibility). In addition, Schwitzgebel's account predicts that people possess an explanation-seeking curiosity that is associated with patterns of arousal and affect when anomalous phenomena are encountered. We present the results of empirical work that demonstrates that students do exhibit strong affective reactions to awareness of experimental anomalies and their resolution.

Investigating Perceptual Biases, Data Reliability, and Data Discovery in a Methodology for Collecting Speech Errors From Audio Recordings.

PubMed

Alderete, John; Davies, Monica

2018-04-01

This work describes a methodology of collecting speech errors from audio recordings and investigates how some of its assumptions affect data quality and composition. Speech errors of all types (sound, lexical, syntactic, etc.) were collected by eight data collectors from audio recordings of unscripted English speech. Analysis of these errors showed that: (i) different listeners find different errors in the same audio recordings, but (ii) the frequencies of error patterns are similar across listeners; (iii) errors collected "online" using on the spot observational techniques are more likely to be affected by perceptual biases than "offline" errors collected from audio recordings; and (iv) datasets built from audio recordings can be explored and extended in a number of ways that traditional corpus studies cannot be.

Reciprocity in computer-human interaction: source-based, norm-based, and affect-based explanations.

PubMed

Lee, Seungcheol Austin; Liang, Yuhua Jake

2015-04-01

Individuals often apply social rules when they interact with computers, and this is known as the Computers Are Social Actors (CASA) effect. Following previous work, one approach to understand the mechanism responsible for CASA is to utilize computer agents and have the agents attempt to gain human compliance (e.g., completing a pattern recognition task). The current study focuses on three key factors frequently cited to influence traditional notions of compliance: evaluations toward the source (competence and warmth), normative influence (reciprocity), and affective influence (mood). Structural equation modeling assessed the effects of these factors on human compliance with computer request. The final model shows that norm-based influence (reciprocity) increased the likelihood of compliance, while evaluations toward the computer agent did not significantly influence compliance.

Dopaminergic contributions to working memory-related brain activation in postmenopausal women.

PubMed

Dumas, Julie A; Filippi, Christopher G; Newhouse, Paul A; Naylor, Magdalena R

2017-02-01

The current study examined the effects of pharmacologic dopaminergic manipulations on working memory-related brain activation in postmenopausal women to further understand the neurochemistry underlying cognition after menopause. Eighteen healthy postmenopausal women, mean age 55.21 years, completed three study days with dopaminergic drug challenges during which they performed a functional magnetic resonance imaging visual verbal N-back test of working memory. Acute stimulation with 1.25 mg oral D2 agonist bromocriptine, acute blockade with 1.5 mg oral haloperidol, and matching placebo were administered randomly and blindly on three study days. We found that dopaminergic stimulation increased activation primarily in the posterior regions of the working memory network compared with dopaminergic blockade using a whole brain cluster-level corrected analysis. The dopaminergic medications did not affect working memory performance. Patterns of increased blood-oxygen-level dependent signal activation after dopaminergic stimulation were found in this study in posterior brain regions with no effect on working memory performance. Further studies should examine specific dopaminergic contributions to brain functioning in healthy postmenopausal women to determine the effects of the increased brain activation on cognition and behavior.

Impact of mobility structure on optimization of small-world networks of mobile agents

NASA Astrophysics Data System (ADS)

Lee, Eun; Holme, Petter

2016-06-01

In ad hoc wireless networking, units are connected to each other rather than to a central, fixed, infrastructure. Constructing and maintaining such networks create several trade-off problems between robustness, communication speed, power consumption, etc., that bridges engineering, computer science and the physics of complex systems. In this work, we address the role of mobility patterns of the agents on the optimal tuning of a small-world type network construction method. By this method, the network is updated periodically and held static between the updates. We investigate the optimal updating times for different scenarios of the movement of agents (modeling, for example, the fat-tailed trip distances, and periodicities, of human travel). We find that these mobility patterns affect the power consumption in non-trivial ways and discuss how these effects can best be handled.

Cultural and environmental influences on temporal-spectral development patterns of corn and soybeans

NASA Technical Reports Server (NTRS)

Crist, E. P.

1982-01-01

A technique for evaluating crop temporal-spectral development patterns is described and applied to the analysis of cropping practices and environmental conditions as they affect reflectance characteristics of corn and soybean canopies. Typical variations in field conditions are shown to exert significant influences on the spectral development patterns, and thereby to affect the separability of the two crops.

Levels, trends and health concerns of atmospheric PAHs in Europe

NASA Astrophysics Data System (ADS)

Garrido, Adrián; Jiménez-Guerrero, Pedro; Ratola, Nuno

2014-12-01

Changes in climate can affect the concentration patterns of polycyclic aromatic hydrocarbons (PAHs) by altering the dispersion (wind speed, mixing layer height, convective fronts), deposition by precipitation, dry deposition, photochemistry, natural emissions and background concentrations. This means the evolution trends of these pollutants have to be studied under a multi-scale perspective, allowing the establishment of transport patterns and distribution of PAHs. In this sense, this work tries to unveil the atmospheric behaviour of these pollutants using temporal data series collected in different stations from the European Monitoring and Evaluation Programme (EMEP) air sampling network. These sites are thought to avoid the direct influence of emitting areas (background stations), allowing the study of long-range transport effects, intra- and trans-annual variability, relationships between concentrations patterns and meteorological variables and latitudinal gradients of PAH levels in Europe. Overall, a typical high concentration pattern was found for the colder months (and an opposite behaviour is found for summertime). Negative trends were detected over high latitudes, for instance, in Svalbard (Norway), whereas for the United Kingdom the pattern is the inverse. Also, negative latitudinal gradients were observed in 4 of the 15 PAHs studied. Finally, air quality parameters revealed concern over human health issues, given the recent increase of BaP levels in Europe.

Body temperature patterns and rhythmicity in free-ranging subterranean Damaraland mole-rats, Fukomys damarensis.

PubMed

Streicher, Sonja; Boyles, Justin G; Oosthuizen, Maria K; Bennett, Nigel C

2011-01-01

Body temperature (T(b)) is an important physiological component that affects endotherms from the cellular to whole organism level, but measurements of T(b) in the field have been noticeably skewed towards heterothermic species and seasonal comparisons are largely lacking. Thus, we investigated patterns of T(b) patterns in a homeothermic, free-ranging small mammal, the Damaraland mole-rat (Fukomys damarensis) during both the summer and winter. Variation in T(b) was significantly greater during winter than summer, and greater among males than females. Interestingly, body mass had only a small effect on variation in T(b) and there was no consistent pattern relating ambient temperature to variation in T(b). Generally speaking, it appears that variation in T(b) patterns varies between seasons in much the same way as in heterothermic species, just to a lesser degree. Both cosinor analysis and Fast Fourier Transform analysis revealed substantial individual variation in T(b) rhythms, even within a single colony. Some individuals had no T(b) rhythms, while others appeared to exhibit multiple rhythms. These data corroborate previous laboratory work showing multiplicity of rhythms in mole-rats and suggest the variation seen in the laboratory is a true indicator of the variation seen in the wild.

Deposition pattern and tracer particle motion of evaporating multi-component sessile droplets.

PubMed

Amjad, Muhammad; Yang, Yang; Raza, Ghulam; Gao, Hui; Zhang, Jun; Zhou, Leping; Du, Xiaoze; Wen, Dongsheng

2017-11-15

The understanding of near-wall motion, evaporation behavior and dry pattern of sessile nanofluid droplets is fundamental to a wide range of applications such as painting, spray drying, thin film coating, fuel injection and inkjet printing. However, a deep insight into the heat transfer, fluid flow, near-wall particle velocity and their effects on the resulting dry patterns is still much needed to take the full advantage of these nano-sized particles in the droplet. This work investigates the effect of direct absorptive silicon/silver (Si/Ag) hybrid nanofluids via two experiments. The first experiment identifies the motion of tracer particles near the triple line of a sessile nanofluid droplet on a super-hydrophilic substrate under ambient conditions by the multilayer nanoparticle image velocimetry (MnPIV) technique. The second experiment reveals the effect of light-sensitive Si/Ag composite nanoparticles on the droplet evaporation rate and subsequent drying patterns under different radiation intensities. The results show that the presence of nanoparticle in a very small proportion significantly affects the motion of tracer particles, leading to different drying patterns and evaporation rates, which can be very important for the applications such as spray coating and inkjet printing. Copyright © 2017 Elsevier Inc. All rights reserved.

Competition between items in working memory leads to forgetting.

PubMed

Lewis-Peacock, Jarrod A; Norman, Kenneth A

2014-12-18

Switching attention from one thought to the next propels our mental lives forward. However, it is unclear how this thought-juggling affects our ability to remember these thoughts. Here we show that competition between the neural representations of pictures in working memory can impair subsequent recognition of those pictures. We use pattern classifiers to decode functional magnetic resonance imaging (fMRI) data from a retro-cueing task where participants juggle two pictures in working memory. Trial-by-trial fluctuations in neural dynamics are predictive of performance on a surprise recognition memory test: trials that elicit similar levels of classifier evidence for both pictures (indicating close competition) are associated with worse memory performance than trials where participants switch decisively from thinking about one picture to the other. This result is consistent with the non-monotonic plasticity hypothesis, which predicts that close competition can trigger weakening of memories that lose the competition, leading to subsequent forgetting.

Structured floral arrangement programme for improving visuospatial working memory in schizophrenia

PubMed Central

Mochizuki-Kawai, Hiroko; Yamakawa, Yuriko; Mochizuki, Satoshi; Anzai, Shoko; Arai, Masanobu

2010-01-01

Several cognitive therapies have been developed for patients with schizophrenia. However, little is known about the outcomes of these therapies in terms of non-verbal/visuospatial working memory, even though this may affect patients’ social outcomes. In the present pilot study, we investigated the effect of a structured floral arrangement (SFA) programme, where participants were required to create symmetrical floral arrangements. In this programme, the arrangement pattern and the order of placing each of the natural materials was predetermined. Participants have to identify where to place each material, and memorise the position temporarily to complete the floral arrangement. The schizophrenic patients who participated in this programme showed significant improvement in their scores for a block-tapping task backward version; whereas, non-treated control patients did not show such an improvement. The present results suggest that the SFA programme may positively stimulate visuospatial working memory in patients. PMID:20467963

Competition between items in working memory leads to forgetting

PubMed Central

Lewis-Peacock, Jarrod A.; Norman, Kenneth A.

2014-01-01

Switching attention from one thought to the next propels our mental lives forward. However, it is unclear how this thought-juggling affects our ability to remember these thoughts. Here we show that competition between the neural representations of pictures in working memory can impair subsequent recognition of those pictures. We use pattern classifiers to decode functional magnetic resonance imaging (fMRI) data from a retro-cueing task where participants juggle two pictures in working memory. Trial-by-trial fluctuations in neural dynamics are predictive of performance on a surprise recognition memory test: trials that elicit similar levels of classifier evidence for both pictures (indicating close competition) are associated with worse memory performance than trials where participants switch decisively from thinking about one picture to the other. This result is consistent with the non-monotonic plasticity hypothesis, which predicts that close competition can trigger weakening of memories that lose the competition, leading to subsequent forgetting. PMID:25519874

Patterns of Harmful Alcohol Consumption among Truck Drivers: Implications for Occupational Health and Work Safety from a Systematic Review and Meta-Analysis.

PubMed

Bragazzi, Nicola Luigi; Dini, Guglielmo; Toletone, Alessandra; Rahmani, Alborz; Montecucco, Alfredo; Massa, Emanuela; Manca, Alessia; Guglielmi, Ottavia; Garbarino, Sergio; Debarbieri, Nicoletta; Durando, Paolo

2018-05-30

Alcohol consumption is one of the main causes of productivity losses arising from absenteeism, presenteeism, and workplace injuries. Among occupational categories most affected by the use of this substance, truck drivers are subject to risk factors and risky behaviors that can have a serious impact on their health, their work, and the general road safety. The use of alcohol during truck-driving activities is, indeed, an important risk factor for traffic accidents. The present systematic review and meta-analysis aims at synthesizing the literature regarding harmful alcohol consumption patterns among truck drivers in a rigorous way. A 'binge drinking' prevalence of 19.0%, 95% confidence interval or CI (13.1, 26.9) was present. An 'everyday drinking' pattern rate of 9.4%, 95% CI (7.0, 12.4) was found, while the rate of alcohol misuse according to the "Alcohol Use Disorders Identification Test" (AUDIT)-"Cut down-Annoyed-Guilty-Eye opener questionnaire" (CAGE) instruments was computed to be of 22.7%, 95% CI (14.8, 33.0). No evidence of publication bias could be found. However, there is the need to improve the quality of published research, utilizing standardized reliable instruments. The knowledge of these epidemiological data can be useful for decision makers in order to develop, design, and implement ad hoc adequate policies.

Modeling Eye Gaze Patterns in Clinician-Patient Interaction with Lag Sequential Analysis

PubMed Central

Montague, E; Xu, J; Asan, O; Chen, P; Chewning, B; Barrett, B

2011-01-01

Objective The aim of this study was to examine whether lag-sequential analysis could be used to describe eye gaze orientation between clinicians and patients in the medical encounter. This topic is particularly important as new technologies are implemented into multi-user health care settings where trust is critical and nonverbal cues are integral to achieving trust. This analysis method could lead to design guidelines for technologies and more effective assessments of interventions. Background Nonverbal communication patterns are important aspects of clinician-patient interactions and may impact patient outcomes. Method Eye gaze behaviors of clinicians and patients in 110-videotaped medical encounters were analyzed using the lag-sequential method to identify significant behavior sequences. Lag-sequential analysis included both event-based lag and time-based lag. Results Results from event-based lag analysis showed that the patients’ gaze followed that of clinicians, while clinicians did not follow patients. Time-based sequential analysis showed that responses from the patient usually occurred within two seconds after the initial behavior of the clinician. Conclusion Our data suggest that the clinician’s gaze significantly affects the medical encounter but not the converse. Application Findings from this research have implications for the design of clinical work systems and modeling interactions. Similar research methods could be used to identify different behavior patterns in clinical settings (physical layout, technology, etc.) to facilitate and evaluate clinical work system designs. PMID:22046723

Methodological considerations in the use of audio diaries in work psychology: Adding to the qualitative toolkit.

PubMed

Crozier, Sarah E; Cassell, Catherine M

2016-06-01

The use of longitudinal methodology as a means of capturing the intricacies in complex organizational phenomena is well documented, and many different research strategies for longitudinal designs have been put forward from both a qualitative and quantitative stance. This study explores a specific emergent qualitative methodology, audio diaries, and assesses their utility for work psychology research drawing on the findings from a four-stage study addressing transient working patterns and stress in UK temporary workers. Specifically, we explore some important methodological, analytical and technical issues for practitioners and researchers who seek to use these methods and explain how this type of methodology has much to offer when studying stress and affective experiences at work. We provide support for the need to implement pluralistic and complementary methodological approaches in unearthing the depth in sense-making and assert their capacity to further illuminate the process orientation of stress. This study illustrates the importance of verbalization in documenting stress and affective experience as a mechanism for accessing cognitive processes in making sense of such experience.This study compares audio diaries with more traditional qualitative methods to assess applicability to different research contexts.This study provides practical guidance and a methodological framework for the design of audio diary research and design, taking into account challenges and solutions for researchers and practitioners.

Everyday life in breast cancer survivors experiencing challenges: A qualitative study.

PubMed

Jakobsen, Klara; Magnus, Eva; Lundgren, Steinar; Reidunsdatter, Randi J

2017-05-31

Early diagnosis and treatment of breast cancer results in an increasing number of survivors, some of whom face new challenges in their transition to daily life. Based on these experiences, the aim of this study was to describe the everyday life in breast cancer survivors experiencing challenges. Eleven women recruited from a follow-up study of breast cancer patients participated in qualitative interviews about their everyday occupations seven years after ending treatment. The inductive analysis revealed ten categories that were organized into five subthemes under the two main themes 'bodily and mental loneliness' and 'new center of gravity in everyday life'. Findings showed how relevant information and guidance; active support to the client and their relatives; and a balance between occupations at home and at work were important matters to handle their everyday life challenges. By assisting these women in finding new patterns of meaningful occupations that positively affect their everyday life, the study suggests some central elements to be included in future follow-up practice for breast cancer survivors. Approaching this goal, occupational therapists should contribute to more involvement assisting cancer survivors and their partners in finding new patterns of meaningful occupations that positively affect their everyday life.

Rigid patterns of effortful choice behavior after acute stress in rats.

PubMed

Hart, Evan E; Stolyarova, Alexandra; Conoscenti, Michael A; Minor, Thomas R; Izquierdo, Alicia

2017-01-01

Physical effort is a common cost of acquiring rewards, and decreased effort is a feature of many neuropsychiatric disorders. Stress affects performance on several tests of cognition and decision making in both humans and nonhumans. Only a few recent reports show impairing effects of stress in operant tasks involving effort and cognitive flexibility. Brain regions affected by stress, such as the medial prefrontal cortex and amygdala, are also implicated in mediating effortful choices. Here, we assessed effort-based decision making after an acute stress procedure known to induce persistent impairment in shuttle escape and elevated plasma corticosterone. In these animals, we also probed levels of polysialyted neural cell adhesion molecule (PSA-NCAM), a marker of structural plasticity, in medial frontal cortex and amygdala. We found that animals that consistently worked for high magnitude rewards continued to do so, even after acute shock stress. We also found that PSA-NCAM was increased in both regions after effortful choice experience but not after shock stress alone. These findings are discussed with reference to the existing broad literature on cognitive effects of stress and in the context of how acute stress may bias effortful decisions to a rigid pattern of responding.

Effect of pin tool design on the material flow of dissimilar AA7075-AA6061 friction stir welds

NASA Astrophysics Data System (ADS)

Hasan, Mohammed M.; Ishak, M.; Rejab, M. R. M.

2017-10-01

Tool design is the most influential aspect in the friction stir welding (FSW) technology. Influence of pin tool geometry on material flow pattern are studied in this work during the FSW of dissimilar AA7075 and AA6061 aluminium alloys. Three truncated pin tool profiles (threaded, threaded with single flat, and unthreaded with single flat) were used to prepare the weldments. The workpieces were joined using a custom-made clamping system under 1100 rpm of spindle speed, 300 mm/min of traverse rate and 3° of tilt angle. The metallographic analysis showed that defect-free welds can be produced using the three pin tools with significant changes in the mixing stir zone structure. The results declared that the introducing of the flat on the cone of the probe deviates the pattern of the onion rings without changing the chemical composition of the created layers. This in turn improves the hardness distribution and tensile strength of the welded joint. It was also noted that both heat affected zone (HAZ) and thermal-mechanical affected zone (TMAZ) are similar in composition to their corresponding base materials (BM).

Interpreting the formation of bloodstains on selected apparel fabrics.

PubMed

de Castro, Therese; Nickson, Tania; Carr, Debra; Knock, Clare

2013-01-01

Bloodstain pattern analysis (BPA) is the investigation and interpretation of blood deposited at crime scenes. However, the interaction of blood and apparel fabrics has not been widely studied. In this work, the development of bloodstains (passive, absorbed and transferred) dropped from three different heights (500, 1,000, 1,500 mm) on two cotton apparel fabrics (1 × 1 rib knit, drill) was investigated. High-speed video was used to investigate the interaction of the blood and fabric at impact. The effect of drop height on the development of passive, absorbed and transferred bloodstains was investigated using image analysis and statistical tools. Visually, the passive bloodstain patterns produced on the technical face of fabrics from the different drop heights were similar. The blood soaked unequally through to the technical rear of both fabrics. Very little blood was transferred between a bloody fabric and a second piece of fabric. Statistically, drop height did not affect the size of the parent bloodstain (wet or dry), but did affect the number of satellite bloodstains formed. Some differences between the two fabrics were noted, therefore fabric structure and properties must be considered when conducting BPA on apparel fabrics.

Association of affect with vertical position in L1 but not in L2 in unbalanced bilinguals

PubMed Central

Li, Degao; Liu, Haitao; Ma, Bosen

2015-01-01

After judging the valence of the positive (e.g., happy) and the negative words (e.g., sad), the participants' response to the letter (q or p) was faster and slower, respectively, when the letter appeared at the upper end than at the lower end of the screen in Meier and Robinson's (2004) second experiment. To compare this metaphorical association of affect with vertical position in Chinese-English bilinguals' first language (L1) and second language (L2) (language), we conducted four experiments in an affective priming task. The targets were one set of positive or negative words (valence), which were shown vertically above or below the center of the screen (position). The primes, presented at the center of the screen, were affective words that were semantically related to the targets, affective words that were not semantically related to the targets, affective icon-pictures, and neutral strings in Experiment 1–4, respectively. In judging the targets' valence, the participants showed different patterns of interactions between language, valence, and position in reaction times across the experiments. We concluded that metaphorical association between affect and vertical position works in L1 but not in L2 for unbalanced bilinguals. PMID:26074847

Resistant to the recession: low-income adults' maintenance of cooking and away-from-home eating behaviors during times of economic turbulence.

PubMed

Smith, Lindsey P; Ng, Shu Wen; Popkin, Barry M

2014-05-01

We examined the effects of state-level unemployment rates during the recession of 2008 on patterns of home food preparation and away-from-home (AFH) eating among low-income and minority populations. We analyzed pooled cross-sectional data on 118 635 adults aged 18 years or older who took part in the American Time Use Study. Multinomial logistic regression models stratified by gender were used to evaluate the associations between state-level unemployment, poverty, race/ethnicity, and time spent cooking, and log binomial regression was used to assess respondents' AFH consumption patterns. High state-level unemployment was associated with only trivial increases in respondents' cooking patterns and virtually no change in their AFH eating patterns. Low-income and racial/ethnic minority groups were not disproportionately affected by the recession. Even during a major economic downturn, US adults are resistant to food-related behavior change. More work is needed to understand whether this reluctance to change is attributable to time limits, lack of knowledge or skill related to food preparation, or lack of access to fresh produce and raw ingredients.

Resistant to the Recession: Low-Income Adults’ Maintenance of Cooking and Away-From-Home Eating Behaviors During Times of Economic Turbulence

PubMed Central

Smith, Lindsey P.; Ng, Shu Wen

2014-01-01

Objectives. We examined the effects of state-level unemployment rates during the recession of 2008 on patterns of home food preparation and away-from-home (AFH) eating among low-income and minority populations. Methods. We analyzed pooled cross-sectional data on 118 635 adults aged 18 years or older who took part in the American Time Use Study. Multinomial logistic regression models stratified by gender were used to evaluate the associations between state-level unemployment, poverty, race/ethnicity, and time spent cooking, and log binomial regression was used to assess respondents’ AFH consumption patterns. Results. High state-level unemployment was associated with only trivial increases in respondents’ cooking patterns and virtually no change in their AFH eating patterns. Low-income and racial/ethnic minority groups were not disproportionately affected by the recession. Conclusions. Even during a major economic downturn, US adults are resistant to food-related behavior change. More work is needed to understand whether this reluctance to change is attributable to time limits, lack of knowledge or skill related to food preparation, or lack of access to fresh produce and raw ingredients. PMID:24625145

Assessing Diversity of DNA Structure-Related Sequence Features in Prokaryotic Genomes

PubMed Central

Huang, Yongjie; Mrázek, Jan

2014-01-01

Prokaryotic genomes are diverse in terms of their nucleotide and oligonucleotide composition as well as presence of various sequence features that can affect physical properties of the DNA molecule. We present a survey of local sequence patterns which have a potential to promote non-canonical DNA conformations (i.e. different from standard B-DNA double helix) and interpret the results in terms of relationships with organisms' habitats, phylogenetic classifications, and other characteristics. Our present work differs from earlier similar surveys not only by investigating a wider range of sequence patterns in a large number of genomes but also by using a more realistic null model to assess significant deviations. Our results show that simple sequence repeats and Z-DNA-promoting patterns are generally suppressed in prokaryotic genomes, whereas palindromes and inverted repeats are over-represented. Representation of patterns that promote Z-DNA and intrinsic DNA curvature increases with increasing optimal growth temperature (OGT), and decreases with increasing oxygen requirement. Additionally, representations of close direct repeats, palindromes and inverted repeats exhibit clear negative trends with increasing OGT. The observed relationships with environmental characteristics, particularly OGT, suggest possible evolutionary scenarios of structural adaptation of DNA to particular environmental niches. PMID:24408877

Screening mosaic F1 females for mutations affecting zebrafish heart induction and patterning.

PubMed

Alexander, J; Stainier, D Y; Yelon, D

1998-01-01

The genetic pathways underlying the induction and anterior-posterior patterning of the heart are poorly understood. The recent emergence of the zebrafish model system now allows a classical genetic approach to such challenging problems in vertebrate development. Two large-scale screens for mutations affecting zebrafish embryonic development have recently been completed; among the hundreds of mutations identified were several that affect specific aspects of cardiac morphogenesis, differentiation, and function. However, very few mutations affecting induction and/or anterior-posterior patterning of the heart were identified. We hypothesize that a directed approach utilizing molecular markers to examine these particular steps of heart development will uncover additional such mutations. To test this hypothesis, we are conducting two parallel screens for mutations that affect either the induction or the anterior-posterior patterning of the zebrafish heart. As an indicator of cardiac induction, we examine expression of nkx2.5, the earliest known marker of precardiac mesoderm; to assess anterior-posterior patterning, we distinguish ventricle from atrium with antibodies that recognize different myosin heavy chain isoforms. In order to expedite the examination of a large number of mutations, we are screening the haploid progeny of mosaic F1 females. In these ongoing screens, we have identified four mutations that affect nkx2.5 expression as well as 21 that disrupt either ventricular or atrial development and thus far have recovered several of these mutations, demonstrating the value of our approach. Future analysis of these and other cardiac mutations will provide further insight into the processes of induction and anterior-posterior patterning of the heart.

Work-Related Pain in Extrinsic Finger Extensor Musculature of Instrumentalists Is Associated with Intracellular pH Compartmentation during Exercise

PubMed Central

Moreno-Torres, Angel; Rosset-Llobet, Jaume; Pujol, Jesus; Fàbregas, Sílvia; Gonzalez-de-Suso, Jose-Manuel

2010-01-01

Background Although non-specific pain in the upper limb muscles of workers engaged in mild repetitive tasks is a common occupational health problem, much is unknown about the associated structural and biochemical changes. In this study, we compared the muscle energy metabolism of the extrinsic finger extensor musculature in instrumentalists suffering from work-related pain with that of healthy control instrumentalists using non-invasive phosphorus magnetic resonance spectroscopy (31P-MRS). We hypothesize that the affected muscles will show alterations related with an impaired energy metabolism. Methodology/Principal Findings We studied 19 volunteer instrumentalists (11 subjects with work-related pain affecting the extrinsic finger extensor musculature and 8 healthy controls). We used 31P-MRS to find deviations from the expected metabolic response to exercise in phosphocreatine (PCr), inorganic phosphate (Pi), Pi/PCr ratio and intracellular pH kinetics. We observed a reduced finger extensor exercise tolerance in instrumentalists with myalgia, an intracellular pH compartmentation in the form of neutral and acid compartments, as detected by Pi peak splitting in 31P-MRS spectra, predominantly in myalgic muscles, and a strong association of this pattern with the condition. Conclusions/Significance Work-related pain in the finger extrinsic extensor muscles is associated with intracellular pH compartmentation during exercise, non-invasively detectable by 31P-MRS and consistent with the simultaneous energy production by oxidative metabolism and glycolysis. We speculate that a deficit in energy production by oxidative pathways may exist in the affected muscles. Two possible explanations for this would be the partial and/or local reduction of blood supply and the reduction of the muscle oxidative capacity itself. PMID:20161738

Contributions of Philip Teitelbaum to affective neuroscience.

PubMed

Berridge, Kent C

2012-06-01

As part of a festschrift issue for Philip Teitelbaum, I offer here the thesis that Teitelbaum deserves to be viewed as an important forefather to the contemporary field of affective neuroscience (which studies motivation, emotion and affect in the brain). Teitelbaum's groundbreaking analyses of motivation deficits induced by lateral hypothalamic damage, of roles of food palatability in revealing residual function, and of recovery of 'lost' functions helped shape modern understanding of how motivation circuits operate within the brain. His redefinition of the minimum requirement for identifying motivation raised the conceptual bar for thinking about the topic among behavioral neuroscientists. His meticulous analyses of patterned stages induced by brain manipulations, life development and clinical disorders added new dimensions to our appreciation of how brain systems work. His steadfast highlighting of integrative functions and behavioral complexity helped provide a healthy functionalist counterbalance to reductionist trends in science of the late 20th century. In short, Philip Teitelbaum can be seen to have made remarkable contributions to several domains of psychology and neuroscience, including affective neuroscience. Copyright © 2011 Elsevier B.V. All rights reserved.

Contributions of Philip Teitelbaum to affective neuroscience

PubMed Central

Berridge, Kent C.

2011-01-01

As part of a festschrift issue for Philip Teitelbaum, I offer here the thesis that Teitelbaum deserves to be viewed as an important forefather to the contemporary field of affective neuroscience (which studies motivation, emotion and affect in the brain). Teitelbaum’s groundbreaking analyses of motivation deficits induced by lateral hypothalamic damage, of roles of food palatability in revealing residual function, and of recovery of ‘lost’ functions helped shape modern understanding of how motivation circuits operate within the brain. His redefinition of the minimum requirement for identifying motivation raised the conceptual bar for thinking about the topic among behavioral neuroscientists. His meticulous analyses of patterned stages induced by brain manipulations, life development and clinical disorders added new dimensions to our appreciation of how brain systems work. His steadfast highlighting of integrative functions and behavioral complexity helped provide a healthy functionalist counterbalance to reductionist trends in science of the late 20th century. In short, Philip Teitelbaum can be seen to have made remarkable contributions to several domains of psychology and neuroscience, including affective neuroscience. PMID:22051942

Optimism, Positive and Negative Affect, and Goal Adjustment Strategies: Their Relationship to Activity Patterns in Patients with Chronic Musculoskeletal Pain.

PubMed

Esteve, Rosa; López-Martínez, Alicia E; Peters, Madelon L; Serrano-Ibáñez, Elena R; Ruiz-Párraga, Gema T; Ramírez-Maestre, Carmen

2018-01-01

Activity patterns are the product of pain and of the self-regulation of current goals in the context of pain. The aim of this study was to investigate the association between goal management strategies and activity patterns while taking into account the role of optimism/pessimism and positive/negative affect. Two hundred and thirty-seven patients with chronic musculoskeletal pain filled out questionnaires on optimism, positive and negative affect, pain intensity, and the activity patterns they employed in dealing with their pain. Questionnaires were also administered to assess their general goal management strategies: goal persistence, flexible goal adjustment, and disengagement and reengagement with goals. Structural equation modelling showed that higher levels of optimism were related to persistence, flexible goal management, and commitment to new goals. These strategies were associated with higher positive affect, persistence in finishing tasks despite pain, and infrequent avoidance behaviour in the presence or anticipation of pain. The strategies used by the patients with chronic musculoskeletal pain to manage their life goals are related to their activity patterns.

Daily Mood Patterns and Bulimic Behaviors in the Natural Environment

PubMed Central

Crosby, Ross D.; Wonderlich, Stephen A.; Engel, Scott G.; Simonich, Heather; Smyth, Joshua; Mitchell, James E.

2009-01-01

Objective Negative affect has been purported to play an important role in the etiology and maintenance of bulimic behaviors. The objective of this study was to identify daily mood patterns in the natural environment exhibited by individuals with bulimia nervosa and to examine the relationship between these patterns and bulimic behaviors. Method One hundred thirty-three women aged 18–55 meeting DSM-IV criteria for bulimia nervosa were recruited through clinical referrals and community advertisements. Ecological momentary assessment was used to collect multiple ratings of negative affect, binge eating and purging each day for a two-week period using palmtop computers. Latent growth mixture modeling was used to identify daily mood patterns. Results Nine distinct daily mood patterns were identified. The highest rates of binge eating and purging episodes occurred on days characterized by stable high negative affect or increasing negative affect over the course of the day. Conclusions These findings support the conclusion that negative mood states are intimately tied to bulimic behaviors and may in fact precipitate such behavior. PMID:19152874

The influence of work patterns on indicators of cardiometabolic risk in female hospital employees.

PubMed

Kirk, Megan; VanDenKerkhof, Elizabeth; Janssen, Ian; Tranmer, Joan

2015-05-01

This study explored the associations between work patterns and indicators of cardiometabolic risk in female hospital employees. Aspects of work environments potentially influence the health of employees; however, we have a poor understanding of how different hospital work patterns contribute to cardiovascular risk in female employees. We conducted a cross-sectional study of 466 female employees from 2 hospitals in Ontario. Data were collected through self-report, physical examination, and use of hospital administrative work data. In the adjusted analyses, full-time work status, extended shift length, and working 35 or more paid overtime hours per year were significantly associated with metabolic syndrome. Different work patterns increase cardiometabolic risk in female employees, suggesting a need to better monitor the health of the workforce and implement healthy workplace policy.

Work-related behaviour and experience patterns of physicians compared to other professions.

PubMed

Voltmer, Edgar; Kieschke, Ulf; Spahn, Claudia

2007-08-11

To identify health risk factors and resources of physicians in comparison with other professions. Data of cross-sectional mail surveys conducted among German physicians (n = 344), teachers (n = 5169), policemen (n = 851), prison officers (n = 3653), and starting entrepreneurs (n = 632) were analysed regarding eleven health-relevant dimensions and four behaviour patterns examined by the questionnaire "Work-Related Behaviour and Experience Pattern (AVEM)". Only 17% of the physicians showed healthy behaviour and experience patterns. With 43%, they scored highest in terms of reduced working motivation. Together with the teachers, they also had the highest scores for resignation and burnout (27%). Satisfaction with life and work as well as social support showed medium scores. Starting entrepreneurs showed the healthiest patterns (45%), but also the highest risk pattern for overexertion (38%). It was possible to identify clear risk patterns for profession-related psychosocial symptoms and impairments. The high scores for reduced working motivation demonstrate the need for interventions to improve organisation of health care and individual coping strategies.

Musculoskeletal injuries among hospital patient care staff before and after implementation of patient lift and transfer equipment.

PubMed

Schoenfisch, Ashley L; Lipscomb, Hester J; Pompeii, Lisa A; Myers, Douglas J; Dement, John M

2013-01-01

Using an observational research design and robust surveillance data, we evaluated rates of musculoskeletal (MS) injuries, days away from work, and restricted work days among patient care staff at a medical center and community hospital in the United States over 13 years, during which time a "minimal manual lift" policy and mechanical lift equipment were implemented. Workers' compensation claims data were linked to human resources data to define outcomes of interest and person-time at risk to calculate rates. Poisson and negative binomial regression with lagging were used to compare outcome rates in different windows of time surrounding the intervention. Patterns of MS injuries associated with patient-handling were contrasted to patterns of other MS injuries that would not be affected by the use of mechanical lift equipment. At the medical center, no change in the patient-handling MS injury rate followed the intervention. A 44% decrease was observed at the community hospital. At both hospitals, the rate of days away declined immediately - before it was reasonable for the intervention to have been adopted. Institutional-level changes at the time of the intervention likely influenced observed results with findings only partially consistent with an intervention effect. Observational studies can be useful in assessing effectiveness of safety interventions in complex work environments. Such studies should consider the process of intervention implementation, the time needed for intervention adoption, and the dynamic nature of work environments.

How work context affects operating room processes: using data mining and computer simulation to analyze facility and process design.

PubMed

Baumgart, André; Denz, Christof; Bender, Hans-Joachim; Schleppers, Alexander

2009-01-01

The complexity of the operating room (OR) requires that both structural (eg, department layout) and behavioral (eg, staff interactions) patterns of work be considered when developing quality improvement strategies. In our study, we investigated how these contextual factors influence outpatient OR processes and the quality of care delivered. The study setting was a German university-affiliated hospital performing approximately 6000 outpatient surgeries annually. During the 3-year-study period, the hospital significantly changed its outpatient OR facility layout from a decentralized (ie, ORs in adjacent areas of the building) to a centralized (ie, ORs in immediate vicinity of each other) design. To study the impact of the facility change on OR processes, we used a mixed methods approach, including process analysis, process modeling, and social network analysis of staff interactions. The change in facility layout was seen to influence OR processes in ways that could substantially affect patient outcomes. For example, we found a potential for more errors during handovers in the new centralized design due to greater interdependency between tasks and staff. Utilization of the mixed methods approach in our analysis, as compared with that of a single assessment method, enabled a deeper understanding of the OR work context and its influence on outpatient OR processes.

Aging and the intrusion superiority effect in visuo-spatial working memory.

PubMed

Cornoldi, Cesare; Bassani, Chiara; Berto, Rita; Mammarella, Nicola

2007-01-01

This study investigated the active component of visuo-spatial working memory (VSWM) in younger and older adults testing the hypotheses that elderly individuals have a poorer performance than younger ones and that errors in active VSWM tasks depend, at least partially, on difficulties in avoiding intrusions (i.e., avoiding already activated information). In two experiments, participants were presented with sequences of matrices on which three positions were pointed out sequentially: their task was to process all the positions but indicate only the final position of each sequence. Results showed a poorer performance in the elderly compared to the younger group and a higher number of intrusion (errors due to activated but irrelevant positions) rather than invention (errors consisting of pointing out a position never indicated by the experiementer) errors. The number of errors increased when a concurrent task was introduced (Experiment 1) and it was affected by different patterns of matrices (Experiment 2). In general, results show that elderly people have an impaired VSWM and produce a large number of errors due to inhibition failures. However, both the younger and the older adults' visuo-spatial working memory was affected by the presence of activated irrelevant information, the reduction of the available resources, and task constraints.

Private primary care physicians' perspectives on factors affecting the adoption of electronic medical records: a qualitative pre-implementation study.

PubMed

Or, Calvin; Wong, Katie; Tong, Ellen; Sek, Antonio

2014-01-01

Use of electronic medical records (EMR) has the potential to offer quality and safety benefits, but without the adoption of the technology, the benefits will not be realized. This study aimed to identify the factors perceived as relevant by private physicians when considering EMR adoption. A qualitative pre-implementation study was conducted using semi-structured, face to face interviews to explore the perspectives of physicians (n=16) operating in private clinics on the factors affecting their adoption of EMR. A multilevel, work system approach and the immersion/crystallization data analysis technique guided the researchers in examining the data, identifying patterns and key themes, and extracting representative quotes to illustrate these themes. The major factors associated with EMR adoption, which relate to the five categories of a work system, were system usefulness; user interface design; technical support; cost; system reliability; the privacy, confidentiality, and security of patient information; physical space in the clinic; data migration process; adverse work-related factors; and the computer and systems skills of physicians. Pre-implementation identification of factors important to adoption can allow system developers to focus proactively on these factors when developing the system and its implementation strategies, to maximize the likelihood of successful introduction.

The effect of working on-call on stress physiology and sleep: A systematic review.

PubMed

Hall, Sarah J; Ferguson, Sally A; Turner, Anne I; Robertson, Samuel J; Vincent, Grace E; Aisbett, Brad

2017-06-01

On-call work is becoming an increasingly common work pattern, yet the human impacts of this type of work are not well established. Given the likelihood of calls to occur outside regular work hours, it is important to consider the potential impact of working on-call on stress physiology and sleep. The aims of this review were to collate and evaluate evidence on the effects of working on-call from home on stress physiology and sleep. A systematic search of Ebsco Host, Embase, Web of Science, Scopus and ScienceDirect was conducted. Search terms included: on-call, on call, standby, sleep, cortisol, heart rate, adrenaline, noradrenaline, nor-adrenaline, epinephrine, norepinephrine, nor-epinephrine, salivary alpha amylase and alpha amylase. Eight studies met the inclusion criteria, with only one study investigating the effect of working on-call from home on stress physiology. All eight studies investigated the effect of working on-call from home on sleep. Working on-call from home appears to adversely affect sleep quantity, and in most cases, sleep quality. However, studies did not differentiate between night's on-call from home with and without calls. Data examining the effect of working on-call from home on stress physiology were not sufficient to draw meaningful conclusions. Copyright © 2016 Elsevier Ltd. All rights reserved.

Income inequality and income segregation.

PubMed

Reardon, Sean F; Bischoff, Kendra

2011-01-01

This article investigates how the growth in income inequality from 1970 to 2000 affected patterns of income segregation along three dimensions: the spatial segregation of poverty and affluence, race-specific patterns of income segregation, and the geographic scale of income segregation. The evidence reveals a robust relationship between income inequality and income segregation, an effect that is larger for black families than for white families. In addition, income inequality affects income segregation primarily through its effect on the large-scale spatial segregation of affluence rather than by affecting the spatial segregation of poverty or by altering small-scale patterns of income segregation.

The Changing Nature and Patterns of Work and Implications for VET. Review of Research.

ERIC Educational Resources Information Center

Waterhouse, Peter; Wilson, Bruce; Ewer, Peter

An overview of recent literature on changes in the nature and patterns of work and their implications for vocational education and training (VET) is offered. Changes in the nature and patterns of work present significant challenges to the VET sector. More women have entered the work force; unemployment has reemerged as a significant factor;…

Local shifts in floral biotic interactions in habitat edges and their effect on quantity and quality of plant offspring

PubMed Central

Fenu, Giuseppe; Bernardo, Liliana

2017-01-01

Abstract Spatial shifts in insect fauna due to ecological heterogeneity can severely constrain plant reproduction. Nonetheless, data showing effects of insect visit patterns and intensity of mutualistic and/or antagonistic plant–insect interactions on plant reproduction over structured ecological gradients remain scarce. We investigated how changes in flower-visitor abundance, identity and behaviour over a forest-open habitat gradient affect plant biotic interactions, and quantitative and qualitative fitness in the edge-specialist Dianthus balbisii. Composition and behaviour of the insects visiting flowers of D. balbisii strongly varied over the study gradient, influencing strength and patterns of plant biotic interactions (i.e. herbivory and pollination likelihood). Seed set comparison in free- and manually pollinated flowers suggested spatial variations in the extent of quantitative pollen limitation, which appeared more pronounced at the gradient extremes. Such variations were congruent to patterns of flower visit and plant biotic interactions. The analyses on seed and seedling viability evidenced that spatial variation in amount and type of pollinators, and frequency of herbivory affected qualitative fitness of D. balbisii by influencing selfing and outcrossing rates. Our work emphasizes the role of plant biotic interactions as a fine-scale mediator of plant fitness in ecotones, highlighting that optimal plant reproduction can take place into a restricted interval of the ecological gradients occurring at forest edges. Reducing the habitat complexity typical of such transition contexts can threat edge-adapted plants. PMID:28775831

Finger patterns and age of onset for the determination of the parent-of-origin in the transmission of schizophrenia

PubMed Central

Ponnudurai, R.; Jayakar, J.

2015-01-01

Summary: Dermatoglyphic traits which are reported to be largely determined by genes could be considered as phenotypic characterestics and if the same are expressed through generations in schizophrenic families it can be speculated to serve as genetic markers for schizophrenia. Another factor that might be influenced by genes is the age of onset of the illness in the offspring and the parent of origin. Objective: This study was aimed to elucidate the occurrence of identical finger patterns in the schizophrenic patients and their affected parents. The other objective was to assess the age of onset of the illness in them. Methods: Forty six schizophrenic patients in whom one of the parents was also affected with schizophrenia or related disorders were recruited. Of these pairs 29 were taken up for finger patterns analysis, with an equal number of control group pairs. 35 proband and parent pairs were investigated for the age of onset of the illness. Results: The frequency of occurrence of identical patterns in the right thumbs of proband and their affected mother pairs was significantly more than between the proband and their affected father pairs. Additionally, the number of identical patterns was also more in the right thumbs of proband and their affected mother pairs compared with the control group. The difference between the mean age of onset of the illness in the probands and their affected fathers was more than between the probands and their affected mothers. Conclusion: The genetic association of schizophrenic patients with the affected maternal side appear to be more stronger than with the paternal side. PMID:25657454

Fluctuating water depths affect American alligator (Alligator mississippiensis) body condition in the Everglades, Florida, USA

USGS Publications Warehouse

Brandt, Laura A.; Beauchamp, Jeffrey S.; Jeffery, Brian M.; Cherkiss, Michael S.; Mazzotti, Frank J.

2016-01-01

Successful restoration of wetland ecosystems requires knowledge of wetland hydrologic patterns and an understanding of how those patterns affect wetland plant and animal populations.Within the Everglades, Florida, USA restoration, an applied science strategy including conceptual ecological models linking drivers to indicators is being used to organize current scientific understanding to support restoration efforts. A key driver of the ecosystem affecting the distribution and abundance of organisms is the timing, distribution, and volume of water flows that result in water depth patterns across the landscape. American alligators (Alligator mississippiensis) are one of the ecological indicators being used to assess Everglades restoration because they are a keystone species and integrate biological impacts of hydrological operations through all life stages. Alligator body condition (the relative fatness of an animal) is one of the metrics being used and targets have been set to allow us to track progress. We examined trends in alligator body condition using Fulton’s K over a 15 year period (2000–2014) at seven different wetland areas within the Everglades ecosystem, assessed patterns and trends relative to restoration targets, and related those trends to hydrologic variables. We developed a series of 17 a priori hypotheses that we tested with an information theoretic approach to identify which hydrologic factors affect alligator body condition. Alligator body condition was highest throughout the Everglades during the early 2000s and is approximately 5–10% lower now (2014). Values have varied by year, area, and hydrology. Body condition was positively correlated with range in water depth and fall water depth. Our top model was the “Current” model and included variables that describe current year hydrology (spring depth, fall depth, hydroperiod, range, interaction of range and fall depth, interaction of range and hydroperiod). Across all models, interaction between range and fall water depth was the most important variable (relative weight of 1.0) followed by spring and fall water depths (0.99), range (0.96), hydroperiod (0.95) and interaction between range and hydroperiod (0.95). Our work provides additional evidence that restoring a greater range in annual water depths is important for improvement of alligator body condition and ecosystem function. This information can be incorporated into both planning and operations to assist in reaching Everglades restoration goals.

Measuring positive and negative affect and physiological hyperarousal among Serbian youth.

PubMed

Stevanovic, Dejan; Laurent, Jeff; Lakic, Aneta

2013-01-01

This study extended previous cross-cultural work regarding the tripartite model of anxiety and depression by developing Serbian translations of the Positive and Negative Affect Scale for Children (PANAS-C), the Physiological Hyperarousal Scale for Children (PH-C), and the Affect and Arousal Scale (AFARS). Characteristics of the scales were examined using 449 students (M age = 12.61 years). Applying item retention criteria established in other studies, PH-C, PANAS-C, and AFARS translations with psychometric properties similar to English-language versions were identified. Preliminary validation of the scales was conducted using a subset of 194 students (M age = 12.37 years) who also completed measures of anxiety and depression. Estimates of reliability, patterns of correlations among scales, and age and gender differences were consistent with previous studies with English-speaking samples. Findings regarding scale validity were mixed, although consistent with existing literature. Serbian translations of the PH-C, PANAS-C, and AFARS mirror the original English-language scales in terms of both strengths and weaknesses.

Understanding Activist Leadership Effort in the Movement Opposing Drinking and Driving

PubMed Central

Dorius, Cassandra R.; McCarthy, John D.

2012-01-01

Why do some social movement leaders work harder than others? And, how does gender affect the patterns we uncover? Utilizing historical case study evidence of local chapters in the emerging movement opposing drinking and driving we are able to develop and test theoretical expectations about predictors of weekly effort among MADD and RID leaders. Taken together, our model explains 45 percent of the variation in leadership effort. We find bureaucratic complexity and victim support activities are more powerful predictors of effort than are individual leader characteristics, although all are important. Further analysis reveals that gender almost wholly conditions the strong effect of bureaucratic complexity on leadership effort so that increasingly complex chapter structures are associated with substantial increases in work hours for women but not men. PMID:22993454

Sleep and Cardio-Metabolic Disease.

PubMed

Cappuccio, Francesco P; Miller, Michelle A

2017-09-19

This review summarises and discusses the epidemiological evidence suggesting a causal relationship between sleep duration and cardio-metabolic risk and outcomes in population. Sleep duration is affected by a variety of cultural, social, psychological, behavioural, pathophysiological and environmental influences. Changes in modern society-like longer working hours, more shift-work, 24/7 availability of commodities and 24-h global connectivity-have been associated with a gradual reduction in sleep duration and sleeping patterns across westernised populations. We review the evidence of an association between sleep disturbances and the development of cardio-metabolic risk and disease and discuss the implications for causality of these associations. Prolonged curtailment of sleep duration is a risk factor for the development of obesity, diabetes, hypertension, heart disease and stroke and may contribute, in the long-term, to premature death.

Impacts of four northern-hemisphere teleconnection patterns on atmospheric circulations over Eurasia and the Pacific

NASA Astrophysics Data System (ADS)

Gao, Tao; Yu, Jin-yi; Paek, Houk

2017-08-01

The impacts of four teleconnection patterns on atmospheric circulation components over Eurasia and the Pacific region, from low to high latitudes in the Northern Hemisphere (NH), were investigated comprehensively in this study. The patterns, as identified by the Climate Prediction Center (USA), were the East Atlantic (EA), East Atlantic/Western Russia (EAWR), Polar/Eurasia (POLEUR), and Scandinavian (SCAND) teleconnections. Results indicate that the EA pattern is closely related to the intensity of the subtropical high over different sectors of the NH in all seasons, especially boreal winter. The wave train associated with this pattern serves as an atmospheric bridge that transfers Atlantic influence into the low-latitude region of the Pacific. In addition, the amplitudes of the EAWR, SCAND, and POLEUR patterns were found to have considerable control on the "Vangengeim-Girs" circulation that forms over the Atlantic-Eurasian region in winter or spring. The EA and EAWR mainly affect the westerlies in winter and spring and the POLEUR and SCAND, respectively, in summer and winter. Strong westerlies confine the extension of the North Polar vortex, which generally results in a small weak vortex and a shallow East Asian trough located in a position further east than normal. Furthermore, the North Polar vortex presents significant connections with the patterns during winter and summer. Analyses in this work suggest that the teleconnection patterns in summer could be driven, at least partly, by the Atlantic Multidecadal Oscillation, which to some degree might transmit the influence of the Atlantic Ocean to Eurasia and the Pacific region.

The affective shift model of work engagement.

PubMed

Bledow, Ronald; Schmitt, Antje; Frese, Michael; Kühnel, Jana

2011-11-01

On the basis of self-regulation theories, the authors develop an affective shift model of work engagement according to which work engagement emerges from the dynamic interplay of positive and negative affect. The affective shift model posits that negative affect is positively related to work engagement if negative affect is followed by positive affect. The authors applied experience sampling methodology to test the model. Data on affective events, mood, and work engagement was collected twice a day over 9 working days among 55 software developers. In support of the affective shift model, negative mood and negative events experienced in the morning of a working day were positively related to work engagement in the afternoon if positive mood in the time interval between morning and afternoon was high. Individual differences in positive affectivity moderated within-person relationships. The authors discuss how work engagement can be fostered through affect regulation. (c) 2011 APA, all rights reserved.

Working Memory From the Psychological and Neurosciences Perspectives: A Review.

PubMed

Chai, Wen Jia; Abd Hamid, Aini Ismafairus; Abdullah, Jafri Malin

2018-01-01

Since the concept of working memory was introduced over 50 years ago, different schools of thought have offered different definitions for working memory based on the various cognitive domains that it encompasses. The general consensus regarding working memory supports the idea that working memory is extensively involved in goal-directed behaviors in which information must be retained and manipulated to ensure successful task execution. Before the emergence of other competing models, the concept of working memory was described by the multicomponent working memory model proposed by Baddeley and Hitch. In the present article, the authors provide an overview of several working memory-relevant studies in order to harmonize the findings of working memory from the neurosciences and psychological standpoints, especially after citing evidence from past studies of healthy, aging, diseased, and/or lesioned brains. In particular, the theoretical framework behind working memory, in which the related domains that are considered to play a part in different frameworks (such as memory's capacity limit and temporary storage) are presented and discussed. From the neuroscience perspective, it has been established that working memory activates the fronto-parietal brain regions, including the prefrontal, cingulate, and parietal cortices. Recent studies have subsequently implicated the roles of subcortical regions (such as the midbrain and cerebellum) in working memory. Aging also appears to have modulatory effects on working memory; age interactions with emotion, caffeine and hormones appear to affect working memory performances at the neurobiological level. Moreover, working memory deficits are apparent in older individuals, who are susceptible to cognitive deterioration. Another younger population with working memory impairment consists of those with mental, developmental, and/or neurological disorders such as major depressive disorder and others. A less coherent and organized neural pattern has been consistently reported in these disadvantaged groups. Working memory of patients with traumatic brain injury was similarly affected and shown to have unusual neural activity (hyper- or hypoactivation) as a general observation. Decoding the underlying neural mechanisms of working memory helps support the current theoretical understandings concerning working memory, and at the same time provides insights into rehabilitation programs that target working memory impairments from neurophysiological or psychological aspects.

Working Memory From the Psychological and Neurosciences Perspectives: A Review

PubMed Central

Chai, Wen Jia; Abd Hamid, Aini Ismafairus; Abdullah, Jafri Malin

2018-01-01

Since the concept of working memory was introduced over 50 years ago, different schools of thought have offered different definitions for working memory based on the various cognitive domains that it encompasses. The general consensus regarding working memory supports the idea that working memory is extensively involved in goal-directed behaviors in which information must be retained and manipulated to ensure successful task execution. Before the emergence of other competing models, the concept of working memory was described by the multicomponent working memory model proposed by Baddeley and Hitch. In the present article, the authors provide an overview of several working memory-relevant studies in order to harmonize the findings of working memory from the neurosciences and psychological standpoints, especially after citing evidence from past studies of healthy, aging, diseased, and/or lesioned brains. In particular, the theoretical framework behind working memory, in which the related domains that are considered to play a part in different frameworks (such as memory’s capacity limit and temporary storage) are presented and discussed. From the neuroscience perspective, it has been established that working memory activates the fronto-parietal brain regions, including the prefrontal, cingulate, and parietal cortices. Recent studies have subsequently implicated the roles of subcortical regions (such as the midbrain and cerebellum) in working memory. Aging also appears to have modulatory effects on working memory; age interactions with emotion, caffeine and hormones appear to affect working memory performances at the neurobiological level. Moreover, working memory deficits are apparent in older individuals, who are susceptible to cognitive deterioration. Another younger population with working memory impairment consists of those with mental, developmental, and/or neurological disorders such as major depressive disorder and others. A less coherent and organized neural pattern has been consistently reported in these disadvantaged groups. Working memory of patients with traumatic brain injury was similarly affected and shown to have unusual neural activity (hyper- or hypoactivation) as a general observation. Decoding the underlying neural mechanisms of working memory helps support the current theoretical understandings concerning working memory, and at the same time provides insights into rehabilitation programs that target working memory impairments from neurophysiological or psychological aspects. PMID:29636715

[From the Auschwitz Syndrome to a Psyche Model--Life and Work of the Polish Psychiatrist Antoni Kepinski (1918-1972)].

PubMed

Schochow, Maximilian; Willer, Manuel; Steger, Florian

2016-01-01

Life and work of the Polish psychiatrist Antoni Kepinski (1918 - 1972) are barely known today, although his writings about the Auschwitz syndrome have had an impact all over the world. We present his biography and work. Compilation and evaluation of literature about Kepinski's work and historical-critical analysis of his key texts. Kepinski's work about the Auschwitz syndrome formed the basis for his understanding of the psyche and his theory on information metabolism. Kepinski posited that the mind processes outside stimuli based on its own set of values and that it determines the subject's actions. In doing so, it affects its environment. If these interactions are disrupted, pathological disorders might result. The therapist should consequently empower the patient to get in touch with his own value-system. Kepinskis work serves as a foundation for research on disease patterns that are known today as post-traumatic stress disorder (PTSD). His theory on information metabolism is essential for the current treatment of patients. It is therefore important to further explore his work and adjust it to the requirements of medical practice. © Georg Thieme Verlag KG Stuttgart · New York.

The work patterns of lactating women in Madura.

PubMed

Launer, L J

1993-08-01

Little is known about the work patterns of mildly malnourished lactating women: are they modified to accommodate the demands of lactation? What factors influence their pattern of work during this period of nutritional stress? These questions were addressed using quantitative and qualitative data collected from 36 randomly selected women living in a poor community in Madura, Indonesia. Work patterns of the lactating women and their family members were documented for the first 12 months post-partum. Changes in work activity were analysed within four time periods corresponding to Madurese views on development during infancy: the vulnerable neonatal (birth-40 days), early (6-12 wk) and mid (13-31 wk) stages and the independent late (32-54 wk) stage. Quantitative data suggest that women did adjust work patterns to accommodate the demands of lactation and that these adjustments went beyond the neonatal stage. Mothers curtailed their participation in high- and low-energy income-generating activities, modified their conditions of work to promote maternal-infant proximity and conserved energy while performing specific activities. These patterns were most common through the mid infancy stage. Data are presented that describe how cultural values supporting maternal-infant proximity, intra- and inter-familial work exchanges, season and resources played a role in the type of accommodations mothers were able to make to breast-feed. These data suggest that even in relatively poor environments alterations in work patterns that may be favourable to lactation are possible, particularly when cultural concepts of infancy support such a trade-off.

Analyzing musculoskeletal neck pain, measured as present pain and periods of pain, with three different regression models: a cohort study.

PubMed

Grimby-Ekman, Anna; Andersson, Eva M; Hagberg, Mats

2009-06-19

In the literature there are discussions on the choice of outcome and the need for more longitudinal studies of musculoskeletal disorders. The general aim of this longitudinal study was to analyze musculoskeletal neck pain, in a group of young adults. Specific aims were to determine whether psychosocial factors, computer use, high work/study demands, and lifestyle are long-term or short-term factors for musculoskeletal neck pain, and whether these factors are important for developing or ongoing musculoskeletal neck pain. Three regression models were used to analyze the different outcomes. Pain at present was analyzed with a marginal logistic model, for number of years with pain a Poisson regression model was used and for developing and ongoing pain a logistic model was used. Presented results are odds ratios and proportion ratios (logistic models) and rate ratios (Poisson model). The material consisted of web-based questionnaires answered by 1204 Swedish university students from a prospective cohort recruited in 2002. Perceived stress was a risk factor for pain at present (PR = 1.6), for developing pain (PR = 1.7) and for number of years with pain (RR = 1.3). High work/study demands was associated with pain at present (PR = 1.6); and with number of years with pain when the demands negatively affect home life (RR = 1.3). Computer use pattern (number of times/week with a computer session > or = 4 h, without break) was a risk factor for developing pain (PR = 1.7), but also associated with pain at present (PR = 1.4) and number of years with pain (RR = 1.2). Among life style factors smoking (PR = 1.8) was found to be associated to pain at present. The difference between men and women in prevalence of musculoskeletal pain was confirmed in this study. It was smallest for the outcome ongoing pain (PR = 1.4) compared to pain at present (PR = 2.4) and developing pain (PR = 2.5). By using different regression models different aspects of neck pain pattern could be addressed and the risk factors impact on pain pattern was identified. Short-term risk factors were perceived stress, high work/study demands and computer use pattern (break pattern). Those were also long-term risk factors. For developing pain perceived stress and computer use pattern were risk factors.

Analyzing musculoskeletal neck pain, measured as present pain and periods of pain, with three different regression models: a cohort study

PubMed Central

Grimby-Ekman, Anna; Andersson, Eva M; Hagberg, Mats

2009-01-01

Background In the literature there are discussions on the choice of outcome and the need for more longitudinal studies of musculoskeletal disorders. The general aim of this longitudinal study was to analyze musculoskeletal neck pain, in a group of young adults. Specific aims were to determine whether psychosocial factors, computer use, high work/study demands, and lifestyle are long-term or short-term factors for musculoskeletal neck pain, and whether these factors are important for developing or ongoing musculoskeletal neck pain. Methods Three regression models were used to analyze the different outcomes. Pain at present was analyzed with a marginal logistic model, for number of years with pain a Poisson regression model was used and for developing and ongoing pain a logistic model was used. Presented results are odds ratios and proportion ratios (logistic models) and rate ratios (Poisson model). The material consisted of web-based questionnaires answered by 1204 Swedish university students from a prospective cohort recruited in 2002. Results Perceived stress was a risk factor for pain at present (PR = 1.6), for developing pain (PR = 1.7) and for number of years with pain (RR = 1.3). High work/study demands was associated with pain at present (PR = 1.6); and with number of years with pain when the demands negatively affect home life (RR = 1.3). Computer use pattern (number of times/week with a computer session ≥ 4 h, without break) was a risk factor for developing pain (PR = 1.7), but also associated with pain at present (PR = 1.4) and number of years with pain (RR = 1.2). Among life style factors smoking (PR = 1.8) was found to be associated to pain at present. The difference between men and women in prevalence of musculoskeletal pain was confirmed in this study. It was smallest for the outcome ongoing pain (PR = 1.4) compared to pain at present (PR = 2.4) and developing pain (PR = 2.5). Conclusion By using different regression models different aspects of neck pain pattern could be addressed and the risk factors impact on pain pattern was identified. Short-term risk factors were perceived stress, high work/study demands and computer use pattern (break pattern). Those were also long-term risk factors. For developing pain perceived stress and computer use pattern were risk factors. PMID:19545386

Rural migration in Nevada: Lincoln County. Phase 1, 1992--1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Soden, D.L.; Carns, D.E.; Mosser, D.

1993-12-31

The principal objective of this project was to develop insight into the scope of migration of working age Nevadans out of their county of birth; including the collection of data on their skill levels, desire to out or in-migrate, interactions between families of migratory persons, and the impact that the proposed high-level nuclear waste repository at Yucca mountain might have on their individual, and collective, decisions to migrate and return. The initial phase of this project reported here was conducted in 1992 and 1993 in Lincoln County, Nevada, one of the counties designated as ``affected`` by the proposed repository program.more » The findings suggest that a serious out-migration problem exists in Lincoln County, and that the Yucca mountain project will likely affect decisions relating to migration patterns in the future.« less

The limits of arousal's memory impairing effects on nearby information

PubMed Central

Mather, Mara; Gorlick, Marissa; Nesmith, Kathryn

2009-01-01

Showing an arousing central stimulus in a scene often leads to enhanced memory for the arousing central information and impaired memory for peripheral details. However, it is not clear from previous work whether arousing stimuli impair memory for all non-arousing nearby information or just background information. In several experiments, we tested how emotionally arousing pictures affect memory for nearby pictures and for background information. We found that when two pictures were presented together, having one of the pictures be arousing did not affect item and location memory for the other picture. In contrast, an arousing picture impaired memory for a background pattern. These findings suggest that arousal impairs memory for information that is the target of perceptual suppression, such as background information when there is a figure-ground distinction, but does not impair memory for other foreground information. PMID:19827704

The limits of arousal's memory-impairing effects on nearby information.

PubMed

Mather, Mara; Gorlick, Marissa A; Nesmith, Kathryn

2009-01-01

Showing an arousing central stimulus in a scene often leads to enhanced memory for the arousing central information and impaired memory for peripheral details. However, it is not clear from previous work whether arousing stimuli impair memory for all nonarousing nearby information or just background information. In several experiments, we tested how emotionally arousing pictures affect memory for nearby pictures and for background information. We found that when 2 pictures were presented together, an arousing picture did not affect item and location memory for the other picture. In contrast, an arousing picture impaired memory for a background pattern. These findings suggest that arousal impairs memory for information that is the target of perceptual suppression, such as background information when there is a figure-ground distinction, but does not impair memory for other foreground information.

The relationship between speech recognition, behavioural listening effort, and subjective ratings.

PubMed

Picou, Erin M; Ricketts, Todd A

2018-06-01

The purpose of this study was to evaluate the reliability and validity of four subjective questions related to listening effort. A secondary purpose of this study was to evaluate the effects of hearing aid beamforming microphone arrays on word recognition and listening effort. Participants answered subjective questions immediately following testing in a dual-task paradigm with three microphone settings in a moderately reverberant laboratory environment in two noise configurations. Participants rated their: (1) mental work, (2) desire to improve the situation, (3) tiredness, and (4) desire to give up. Data were analysed using repeated measures and reliability analyses. Eighteen adults with symmetrical sensorineural hearing loss participated. Beamforming differentially affected word recognition and listening effort. Analysis revealed the same pattern of results for behavioural listening effort and subjective ratings of desire to improve the situation. Conversely, ratings of work revealed the same pattern of results as word recognition performance. Ratings of tiredness and desire to give up were unaffected by hearing aid microphone or noise configuration. Participant ratings of their desire to control the listening situation appear to reliable subjective indicators of listening effort that align with results from a behavioural measure of listening effort.

On the distribution of interspecies correlation for Markov models of character evolution on Yule trees.

PubMed

Mulder, Willem H; Crawford, Forrest W

2015-01-07

Efforts to reconstruct phylogenetic trees and understand evolutionary processes depend fundamentally on stochastic models of speciation and mutation. The simplest continuous-time model for speciation in phylogenetic trees is the Yule process, in which new species are "born" from existing lineages at a constant rate. Recent work has illuminated some of the structural properties of Yule trees, but it remains mostly unknown how these properties affect sequence and trait patterns observed at the tips of the phylogenetic tree. Understanding the interplay between speciation and mutation under simple models of evolution is essential for deriving valid phylogenetic inference methods and gives insight into the optimal design of phylogenetic studies. In this work, we derive the probability distribution of interspecies covariance under Brownian motion and Ornstein-Uhlenbeck models of phenotypic change on a Yule tree. We compute the probability distribution of the number of mutations shared between two randomly chosen taxa in a Yule tree under discrete Markov mutation models. Our results suggest summary measures of phylogenetic information content, illuminate the correlation between site patterns in sequences or traits of related organisms, and provide heuristics for experimental design and reconstruction of phylogenetic trees. Copyright © 2014 Elsevier Ltd. All rights reserved.

The Risk Implications of Globalisation: An Exploratory Analysis of 105 Major Industrial Incidents (1971-2010).

PubMed

Beck, Matthias

2016-03-10

This paper revisits work on the socio-political amplification of risk, which predicts that those living in developing countries are exposed to greater risk than residents of developed nations. This prediction contrasts with the neoliberal expectation that market driven improvements in working conditions within industrialising/developing nations will lead to global convergence of hazard exposure levels. It also contradicts the assumption of risk society theorists that there will be an ubiquitous increase in risk exposure across the globe, which will primarily affect technically more advanced countries. Reviewing qualitative evidence on the impact of structural adjustment reforms in industrialising countries, the export of waste and hazardous waste recycling to these countries and new patterns of domestic industrialisation, the paper suggests that workers in industrialising countries continue to face far greater levels of hazard exposure than those of developed countries. This view is confirmed when a data set including 105 major multi-fatality industrial disasters from 1971 to 2000 is examined. The paper concludes that there is empirical support for the predictions of socio-political amplification of risk theory, which finds clear expression in the data in a consistent pattern of significantly greater fatality rates per industrial incident in industrialising/developing countries.

Self-regulation via neural simulation

PubMed Central

Gilead, Michael; Boccagno, Chelsea; Silverman, Melanie; Hassin, Ran R.; Weber, Jochen; Ochsner, Kevin N.

2016-01-01

Can taking the perspective of other people modify our own affective responses to stimuli? To address this question, we examined the neurobiological mechanisms supporting the ability to take another person’s perspective and thereby emotionally experience the world as they would. We measured participants’ neural activity as they attempted to predict the emotional responses of two individuals that differed in terms of their proneness to experience negative affect. Results showed that behavioral and neural signatures of negative affect (amygdala activity and a distributed multivoxel pattern reflecting affective negativity) simulated the presumed affective state of the target person. Furthermore, the anterior medial prefrontal cortex (mPFC)—a region implicated in mental state inference—exhibited a perspective-dependent pattern of connectivity with the amygdala, and the multivoxel pattern of activity within the mPFC differentiated between the two targets. We discuss the implications of these findings for research on perspective-taking and self-regulation. PMID:27551094

Deep brain stimulation changes basal ganglia output nuclei firing pattern in the dystonic hamster.

PubMed

Leblois, Arthur; Reese, René; Labarre, David; Hamann, Melanie; Richter, Angelika; Boraud, Thomas; Meissner, Wassilios G

2010-05-01

Dystonia is a heterogeneous syndrome of movement disorders characterized by involuntary muscle contractions leading to abnormal movements and postures. While medical treatment is often ineffective, deep brain stimulation (DBS) of the internal pallidum improves dystonia. Here, we studied the impact of DBS in the entopeduncular nucleus (EP), the rodent equivalent of the human globus pallidus internus, on basal ganglia output in the dt(sz)-hamster, a well-characterized model of dystonia by extracellular recordings. Previous work has shown that EP-DBS improves dystonic symptoms in dt(sz)-hamsters. We report that EP-DBS changes firing pattern in the EP, most neurons switching to a less regular firing pattern during DBS. In contrast, EP-DBS did not change the average firing rate of EP neurons. EP neurons display multiphasic responses to each stimulation impulse, likely underlying the disruption of their firing rhythm. Finally, neurons in the substantia nigra pars reticulata display similar responses to EP-DBS, supporting the idea that EP-DBS affects basal ganglia output activity through the activation of common afferent fibers. Copyright 2010 Elsevier Inc. All rights reserved.

An image analysis of TLC patterns for quality control of saffron based on soil salinity effect: A strategy for data (pre)-processing.

PubMed

Sereshti, Hassan; Poursorkh, Zahra; Aliakbarzadeh, Ghazaleh; Zarre, Shahin; Ataolahi, Sahar

2018-01-15

Quality of saffron, a valuable food additive, could considerably affect the consumers' health. In this work, a novel preprocessing strategy for image analysis of saffron thin layer chromatographic (TLC) patterns was introduced. This includes performing a series of image pre-processing techniques on TLC images such as compression, inversion, elimination of general baseline (using asymmetric least squares (AsLS)), removing spots shift and concavity (by correlation optimization warping (COW)), and finally conversion to RGB chromatograms. Subsequently, an unsupervised multivariate data analysis including principal component analysis (PCA) and k-means clustering was utilized to investigate the soil salinity effect, as a cultivation parameter, on saffron TLC patterns. This method was used as a rapid and simple technique to obtain the chemical fingerprints of saffron TLC images. Finally, the separated TLC spots were chemically identified using high-performance liquid chromatography-diode array detection (HPLC-DAD). Accordingly, the saffron quality from different areas of Iran was evaluated and classified. Copyright © 2017 Elsevier Ltd. All rights reserved.

Reaction-diffusion systems and external morphogen gradients: the two-dimensional case, with an application to skeletal pattern formation.

PubMed

Glimm, Tilmann; Zhang, Jianying; Shen, Yun-Qiu; Newman, Stuart A

2012-03-01

We investigate a reaction-diffusion system consisting of an activator and an inhibitor in a two-dimensional domain. There is a morphogen gradient in the domain. The production of the activator depends on the concentration of the morphogen. Mathematically, this leads to reaction-diffusion equations with explicitly space-dependent terms. It is well known that in the absence of an external morphogen, the system can produce either spots or stripes via the Turing bifurcation. We derive first-order expansions for the possible patterns in the presence of an external morphogen and show how both stripes and spots are affected. This work generalizes previous one-dimensional results to two dimensions. Specifically, we consider the quasi-one-dimensional case of a thin rectangular domain and the case of a square domain. We apply the results to a model of skeletal pattern formation in vertebrate limbs. In the framework of reaction-diffusion models, our results suggest a simple explanation for some recent experimental findings in the mouse limb which are much harder to explain in positional-information-type models.

Partial connectivity increases cultural accumulation within groups.

PubMed

Derex, Maxime; Boyd, Robert

2016-03-15

Complex technologies used in most human societies are beyond the inventive capacities of individuals. Instead, they result from a cumulative process in which innovations are gradually added to existing cultural traits across many generations. Recent work suggests that a population's ability to develop complex technologies is positively affected by its size and connectedness. Here, we present a simple computer-based experiment that compares the accumulation of innovations by fully and partially connected groups of the same size in a complex fitness landscape. We find that the propensity to learn from successful individuals drastically reduces cultural diversity within fully connected groups. In comparison, partially connected groups produce more diverse solutions, and this diversity allows them to develop complex solutions that are never produced in fully connected groups. These results suggest that explanations of ancestral patterns of cultural complexity may need to consider levels of population fragmentation and interaction patterns between partially isolated groups.

Partial connectivity increases cultural accumulation within groups

PubMed Central

Boyd, Robert

2016-01-01

Complex technologies used in most human societies are beyond the inventive capacities of individuals. Instead, they result from a cumulative process in which innovations are gradually added to existing cultural traits across many generations. Recent work suggests that a population’s ability to develop complex technologies is positively affected by its size and connectedness. Here, we present a simple computer-based experiment that compares the accumulation of innovations by fully and partially connected groups of the same size in a complex fitness landscape. We find that the propensity to learn from successful individuals drastically reduces cultural diversity within fully connected groups. In comparison, partially connected groups produce more diverse solutions, and this diversity allows them to develop complex solutions that are never produced in fully connected groups. These results suggest that explanations of ancestral patterns of cultural complexity may need to consider levels of population fragmentation and interaction patterns between partially isolated groups. PMID:26929364

Thalamic abnormalities are a cardinal feature of alcohol-related brain dysfunction.

PubMed

Pitel, Anne Lise; Segobin, Shailendra H; Ritz, Ludivine; Eustache, Francis; Beaunieux, Hélène

2015-07-01

Two brain networks are particularly affected by the harmful effect of chronic and excessive alcohol consumption: the circuit of Papez and the frontocerebellar circuit, in both of which the thalamus plays a key role. Shrinkage of the thalamus is more severe in alcoholics with Korsakoff's syndrome (KS) than in those without neurological complication (AL). In accordance with the gradient effect of thalamic abnormalities between AL and KS, the pattern of brain dysfunction in the Papez's circuit results in anterograde amnesia in KS and only mild-to-moderate episodic memory disorders in AL. On the opposite, dysfunction of the frontocerebellar circuit results in a similar pattern of working memory and executive deficits in the AL and KS. Several hypotheses, mutually compatible, can be drawn to explain that the severe thalamic shrinkage observed in KS has different consequences in the neuropsychological profile associated with the two brain networks. Copyright © 2014. Published by Elsevier Ltd.

Fast parallel 3D profilometer with DMD technology

NASA Astrophysics Data System (ADS)

Hou, Wenmei; Zhang, Yunbo

2011-12-01

Confocal microscope has been a powerful tool for three-dimensional profile analysis. Single mode confocal microscope is limited by scanning speed. This paper presents a 3D profilometer prototype of parallel confocal microscope based on DMD (Digital Micromirror Device). In this system the DMD takes the place of Nipkow Disk which is a classical parallel scanning scheme to realize parallel lateral scanning technique. Operated with certain pattern, the DMD generates a virtual pinholes array which separates the light into multi-beams. The key parameters that affect the measurement (pinhole size and the lateral scanning distance) can be configured conveniently by different patterns sent to DMD chip. To avoid disturbance between two virtual pinholes working at the same time, a scanning strategy is adopted. Depth response curve both axial and abaxial were extract. Measurement experiments have been carried out on silicon structured sample, and axial resolution of 55nm is achieved.

The sleep needs of adolescents.

PubMed

Kelman, B B

1999-08-01

The amount of sleep affects the way adolescents perform, feel, think, learn, and remember. Significant physiological and social changes have profound effects on adolescents' sleeping patterns. Lack of sleep increases the possibility of increased daytime sleepiness, which may result in a tragic automobile or work accident. Other consequences of sleep deprivation include poor school performance, heightened risk of drug and alcohol use, increased irritability, and aggressive behavior, all of which can interfere with relationships with classmates, parents, and teachers. The purpose of this paper is to explore the literature concerning what is known about why adolescents need more sleep and why adolescents do not obtain enough sleep. Nursing interventions targeting adolescents, parents, teachers, schools, and employers are included. If adolescents understand and learn to improve their sleep patterns while they are young, they may have improved sleep habits in adulthood. Teaching adolescents about the importance of sleep is an important task for school nurses.

Performance of μ-RWELL detector vs resistivity of the resistive stage

NASA Astrophysics Data System (ADS)

Bencivenni, G.; De Oliveira, R.; Felici, G.; Gatta, M.; Morello, G.; Ochi, A.; Lener, M. Poli; Tskhadadze, E.

2018-04-01

The μ-RWELL is a compact spark-protected single amplification stage Micro-Pattern-Gaseous-Detector (MPGD). The detector amplification stage is realized with a polyimide structure, micro-patterned with a dense matrix of blind-holes, integrated into the readout structure. The anode is formed by a thin Diamond Like Carbon (DLC) resistive layer separated by an insulating glue layer from the readout strips. The introduction of the resistive layer strongly suppressing the transition from streamer to spark gives the possibility to achieve large gains (> 104), without significantly affecting the capability to be efficiently operated in high particle fluxes. In this work we present the results of a systematic study of the μ-RWELL performance as a function of the DLC resistivity. The tests have been performed either with collimated 5.9 keV X-rays or with pion and muon beams at the SPS Secondary Beamline H4 and H8 at CERN.

Modulation of working memory function by motivation through loss-aversion.

PubMed

Krawczyk, Daniel C; D'Esposito, Mark

2013-04-01

Cognitive performance is affected by motivation. Few studies, however, have investigated the neural mechanisms of the influence of motivation through potential monetary punishment on working memory. We employed functional MRI during a delayed recognition task that manipulated top-down control demands with added monetary incentives to some trials in the form of potential losses of bonus money. Behavioral performance on the task was influenced by loss-threatening incentives in the form of faster and more accurate performance. As shown previously, we found enhancement of activity for relevant stimuli occurs throughout all task periods (e.g., stimulus encoding, maintenance, and response) in both prefrontal and visual association cortex. Further, these activation patterns were enhanced for trials with possible monetary loss relative to nonincentive trials. During the incentive cue, the amygdala and striatum showed significantly greater activation when money was at a possible loss on the trial. We also evaluated patterns of functional connectivity between regions responsive to monetary consequences and prefrontal areas responsive to the task. This analysis revealed greater delay period connectivity between and the left insula and prefrontal cortex with possible monetary loss relative to nonincentive trials. Overall, these results reveal that incentive motivation can modulate performance on working memory tasks through top-down signals via amplification of activity within prefrontal and visual association regions selective to processing the perceptual inputs of the stimuli to be remembered. Copyright © 2011 Wiley Periodicals, Inc.

Modulation of working memory function by motivation through loss-aversion

PubMed Central

Krawczyk, Daniel C.; D’Esposito, Mark

2012-01-01

Cognitive performance is affected by motivation. Few studies, however, have investigated the neural mechanisms of the influence of motivation through potential monetary punishment on working memory. We employed functional MRI during a delayed recognition task that manipulated top-down control demands with added monetary incentives to some trials in the form of potential losses of bonus money. Behavioral performance on the task was influenced by loss-threatening incentives in the form of faster and more accurate performance. As shown previously, we found enhancement of activity for relevant stimuli occurs throughout all task periods (e.g. stimulus encoding, maintenance, and response) in both prefrontal and visual association cortex. Further, these activation patterns were enhanced for trials with possible monetary loss relative to non-incentive trials. During the incentive cue, the amygdala and striatum showed significantly greater activation when money was at a possible loss on the trial. We also evaluated patterns of functional connectivity between regions responsive to monetary consequences and prefrontal areas responsive to the task. This analysis revealed greater delay period connectivity between and the left insula and prefrontal cortex with possible monetary loss relative to non-incentive trials. Overall, these results reveal that incentive motivation can modulate performance on working memory tasks through top-down signals via amplification of activity within prefrontal and visual association regions selective to processing the perceptual inputs of the stimuli to be remembered. PMID:22113962

76 FR 35801 - Examinations of Work Areas in Underground Coal Mines and Pattern of Violations

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-20

..., 1219-AB73 Examinations of Work Areas in Underground Coal Mines and Pattern of Violations AGENCY: Mine... public hearings on the Agency's proposed rules for Examinations of Work Areas in Underground Coal Mines... Underground Coal Mines' submissions, and with ``RIN 1219-AB73'' for Pattern of Violations' submissions...

Lifetime Achievement Patterns, Retirement and Life Satisfaction of Gifted Aged Women.

ERIC Educational Resources Information Center

Holahan, Carole Kovalic

1981-01-01

Investigated the relationship of lifetime achievement patterns and retirement, to life satisfaction for gifted aging women (N=352). Results showed a significant interaction between marital status and work pattern on overall life satisfaction suggesting an additive negative effect of loss of spouse and a work history of working for income alone.…

Management, Governance and Leadership: A Guide for College and University Administrators.

ERIC Educational Resources Information Center

Millett, John D.

Perspectives on management, governance, and leadership of the university are presented. The following organizational characteristics are discussed: sense of purpose, work specialization, work technology, pattern of cooperation, pattern of management, pattern of governance, and pattern of leadership. The following purposes of American colleges and…

Dental ergonomics to combat musculoskeletal disorders: a review.

PubMed

Gupta, Arpit; Ankola, Anil V; Hebbal, Mamata

2013-01-01

Musculoskeletal disorders (MSDs) are significant workplace problems affecting occupational health, productivity and the careers of dental professionals. The prevalence of MSDs is on the rise for all types of dental workers. In spite of different patterns of work culture, there are parallel levels of symptoms in dentists across nations. Risk factors for MSDs are multifactorial. Symptoms appear very early in careers, with higher prevalence of MSDs even during educational training. Ergonomics improvements, health promotion and organizational interventions are necessary to reduce the risk. An interdisciplinary approach with progressive efforts should be taken to address MSDs in dental professionals.

Spatial patterns in community response to aircraft noise associated with non-noise factors

NASA Astrophysics Data System (ADS)

Hall, F. L.; Taylor, S. M.; Birnie, S. E.

1980-08-01

Non-noise aspects of airport operations may affect individuals' responses to aircraft noise. Fear of crashes, other forms of pollution, and proximity to the flight path are three such non-noise aspects which have spatial patterns that are closely related to the pattern of noise contours around an airport. If these variables affect response to aircraft noise, they may therefore confound attempts to understand relationships between noise level and community response. Analyses based on data from 673 individuals around Toronto International Airport suggest that these factors do affect annoyance responses, but do not affect reported activity interference. Hence it may prove fruitful, in aggregate analyses of community response data, to control for these variables in order to better understand the noise-annoyance relationships.

Work step indication with grid-pattern projection for demented senior people.

PubMed

Uranishi, Yuki; Yamamoto, Goshiro; Asghar, Zeeshan; Pulli, Petri; Kato, Hirokazu; Oshiro, Osamu

2013-01-01

This paper proposes a work step indication method for supporting daily work with a grid-pattern projection. To support an independent life of demented senior people, it is desirable that an instruction is easy to understand visually and not complicated. The proposed method in this paper uses a range image sensor and a camera in addition to a projector. A 3D geometry of a target scene is measured by the range image sensor, and the grid-pattern is projected onto the scene directly. Direct projection of the work step is easier to be associated with the target objects around the assisted person, and the grid-pattern is a solution to indicate the spatial instruction. A prototype has been implemented and has demonstrated that the proposed grid-pattern projection is easy to show the work step.

Work-related risk factors for neck pain in the US working population.

PubMed

Yang, Haiou; Haldeman, Scott; Nakata, Akinori; Choi, BongKyoo; Delp, Linda; Baker, Dean

2015-02-01

This study uses the Taylor linearized variance estimation method to compute weighted unadjusted and adjusted prevalence of neck pain by occupation, with a cross-section data set from the 2009 to 2012 National Health Interview Survey. The goal of this study was to explore occupational patterns of neck pain and the relationship between long work hours and neck pain in the working population in the United States. The past research has demonstrated that specific occupations have a high prevalence of neck pain. However, occupational patterns of neck pain in the United States have been understudied. Risk of neck pain was estimated using univariate and multivariate logistic regression with odds ratios (ORs) with 95% confidence interval (CI) as measures of association. After controlling for demographic, socioeconomic status, and behavior-related factors and compared with workers in architecture and engineering occupation group, the top 5 occupational groups with significantly higher relative prevalence of neck pain included: military specific (OR, 2.50; 95% CI, 1.17-5.35); arts, design, entertainment, sports, and media (OR, 1.70; 95% CI, 1.34-2.17); life, physical, and social science (OR, 1.67; 95% CI, 1.33-2.11); health care support (OR, 1.55; 95% CI, 1.23-1.97); and installation, maintenance, and repair (OR, 1.54; 95% CI, 1.21-1.96). Compared with those who worked 40 hours, people who worked 46 to 59 hours (OR, 1.20; 95% CI, 1.10-1.30) and 60 or more hours of work per week (OR, 1.35; 95% CI-1.21, 1.51) were more likely to report neck pain. This study adds to the evidence that an individual's occupation and work hours affect workers' risk for neck pain. This study indicates a need for new research efforts and public policies targeted to workers who are susceptible to neck pain in the United States. 1.

The impact of shift work on eating patterns and self-care strategies utilised by experienced and inexperienced nurses.

PubMed

Gifkins, Jane; Johnston, Amy; Loudoun, Rebecca

2018-05-08

For nurses, shift work is a necessity, required to provide 24-h continuous care for patients. Research posits that fatigue amongst shift-working nurses is associated with inadequate and poorly timed sleep and also strongly influenced by the timing, quality and quantity of food consumed. The aim of this investigation was to examine differences and similarities in the food choices and eating patterns of nurses exposed to different lengths of time in shift work, as a means of understanding how nurses can adapt their eating patterns to better manage fatigue and sleep loss. Qualitative methodology was utilised to study and capture in-depth information about nurses' daily working lives. A case study approach allowed for the investigation of nurses with limited and extensive experience of shift work. Increased food craving, caffeine consumption and snacking behaviours during night shifts were described by both groups of nurses, as was the inability to drink enough fluids at work. Meal skipping at work, associated with high workload, was detailed more by experienced nurses. Experienced nurses described shopping and preparing home cooked meals in advance to manage food intake and associated fatigue, contrasting with patterns from inexperienced nurses. Experienced nurses recounted drinking alcohol as a way to rest and recover from shift work, unlike their less inexperienced colleagues. These findings indicate organisational and work place issues such as shift work and rostering influence the food choices and eating patterns of shift-working nurses. Experienced nurses, however, draw on a greater range of strategies around diet and eating patterns to minimise these impacts.

A framework for analyzing the relationship between gene expression and morphological, topological, and dynamical patterns in neuronal networks.

PubMed

de Arruda, Henrique Ferraz; Comin, Cesar Henrique; Miazaki, Mauro; Viana, Matheus Palhares; Costa, Luciano da Fontoura

2015-04-30

A key point in developmental biology is to understand how gene expression influences the morphological and dynamical patterns that are observed in living beings. In this work we propose a methodology capable of addressing this problem that is based on estimating the mutual information and Pearson correlation between the intensity of gene expression and measurements of several morphological properties of the cells. A similar approach is applied in order to identify effects of gene expression over the system dynamics. Neuronal networks were artificially grown over a lattice by considering a reference model used to generate artificial neurons. The input parameters of the artificial neurons were determined according to two distinct patterns of gene expression and the dynamical response was assessed by considering the integrate-and-fire model. As far as single gene dependence is concerned, we found that the interaction between the gene expression and the network topology, as well as between the former and the dynamics response, is strongly affected by the gene expression pattern. In addition, we observed a high correlation between the gene expression and some topological measurements of the neuronal network for particular patterns of gene expression. To our best understanding, there are no similar analyses to compare with. A proper understanding of gene expression influence requires jointly studying the morphology, topology, and dynamics of neurons. The proposed framework represents a first step towards predicting gene expression patterns from morphology and connectivity. Copyright © 2015. Published by Elsevier B.V.

Discrimination between glycosylation patterns of therapeutic antibodies using a microfluidic platform, MALDI-MS and multivariate statistics.

PubMed

Thuy, Tran Thi; Tengstrand, Erik; Aberg, Magnus; Thorsén, Gunnar

2012-11-01

Optimal glycosylation with respect to the efficacy, serum half-life time, and immunogenic properties is essential in the generation of therapeutic antibodies. The glycosylation pattern can be affected by several different parameters during the manufacture of antibodies and may change significantly over cultivation time. Fast and robust methods for determination of the glycosylation patterns of therapeutic antibodies are therefore needed. We have recently presented an efficient method for the determination of glycans on therapeutic antibodies using a microfluidic CD platform for sample preparation prior to matrix-assisted laser-desorption mass spectrometry analysis. In the present work, this method is applied to analyse the glycosylation patterns of three commercially available therapeutic antibodies and one intended for therapeutic use. Two of the antibodies produced in mouse myeloma cell line (SP2/0) and one produced in Chinese hamster ovary (CHO) cells exhibited similar glycosylation patterns but could still be readily differentiated from each other using multivariate statistical methods. The two antibodies with most similar glycosylation patterns were also studied in an assessment of the method's applicability for quality control of therapeutic antibodies. The method presented in this paper is highly automated and rapid. It can therefore efficiently generate data that helps to keep a production process within the desired design space or assess that an identical product is being produced after changes to the process. Copyright © 2012 Elsevier B.V. All rights reserved.

Remote Sensing-Based Detection and Spatial Pattern Analysis for Geo-Ecological Niche Modeling of Tillandsia SPP. In the Atacama, Chile

NASA Astrophysics Data System (ADS)

Wolf, N.; Siegmund, A.; del Río, C.; Osses, P.; García, J. L.

2016-06-01

In the coastal Atacama Desert in Northern Chile plant growth is constrained to so-called `fog oases' dominated by monospecific stands of the genus Tillandsia. Adapted to the hyperarid environmental conditions, these plants specialize on the foliar uptake of fog as main water and nutrient source. It is this characteristic that leads to distinctive macro- and micro-scale distribution patterns, reflecting complex geo-ecological gradients, mainly affected by the spatiotemporal occurrence of coastal fog respectively the South Pacific Stratocumulus clouds reaching inlands. The current work employs remote sensing, machine learning and spatial pattern/GIS analysis techniques to acquire detailed information on the presence and state of Tillandsia spp. in the Tarapacá region as a base to better understand the bioclimatic and topographic constraints determining the distribution patterns of Tillandsia spp. Spatial and spectral predictors extracted from WorldView-3 satellite data are used to map present Tillandsia vegetation in the Tarapaca region. Regression models on Vegetation Cover Fraction (VCF) are generated combining satellite-based as well as topographic variables and using aggregated high spatial resolution information on vegetation cover derived from UAV flight campaigns as a reference. The results are a first step towards mapping and modelling the topographic as well as bioclimatic factors explaining the spatial distribution patterns of Tillandsia fog oases in the Atacama, Chile.

Parental History of Diabetes, Positive Affect, and Diabetes Risk in Adults: Findings from MIDUS.

PubMed

Tsenkova, Vera K; Karlamangla, Arun S; Ryff, Carol D

2016-12-01

Family history of diabetes is one of the major risk factors for diabetes, but significant variability in this association remains unexplained, suggesting the presence of important effect modifiers. To our knowledge, no previous work has examined whether psychological factors moderate the degree to which family history of diabetes increases diabetes risk. We investigated the relationships among parental history of diabetes, affective states (positive affect, negative affect, and depressed affect), and diabetes in 978 adults from the MIDUS 2 national sample. As expected, parental history of diabetes was associated with an almost threefold increase in diabetes risk. We found a significant interaction between positive affect and parental history of diabetes on diabetes (p = .009): higher positive affect was associated with a statistically significant lower relative risk for diabetes in participants who reported having a parental history of diabetes (RR = .66 per unit increase in positive affect; 95 % CI = .47; .93), but it did not influence diabetes risk for participants who reported no parental history of diabetes (p = .34). This pattern persisted after adjusting for an extensive set of health and sociodemographic covariates and was independent of negative and depressed affect. These results suggest that psychological well-being may protect individuals at increased risk from developing diabetes. Understanding such interactions between non-modifiable risk factors and modifiable psychological resources is important for delineating biopsychosocial pathways to diabetes and informing theory-based, patient-centered interventions to prevent the development of diabetes.

Factors affecting first return to work following a compensable occupational back injury.

PubMed

Oleinick, A; Gluck, J V; Guire, K

1996-11-01

Occupational back injuries produced $27 billion in direct and indirect costs in 1988. Predictors of prolonged disability have generally been identified in selected clinical populations, but there have been few population-based studies using statewide registries from workers' compensation systems. This study uses a 1986 cohort of 8,628 Michigan workers with compensable back injuries followed to March 1, 1990. Cox proportional hazards analyses with nine categorical covariates identified factors predicting missed worktime for the first disability episode following the injury. The model distinguished factors affecting the acute (< or = 8 weeks) and chronic disability periods (> 8 weeks). The first disability episode following injury contains 69.6% of the missed worktime observed through follow-up. In the acute phase, which contributes 15.2% of first episode missed worktime, gender, age, number of dependents, industry (construction), occupation, and type of accident predict continued work disability. Marital status, weekly wage compensation rate, and establishment size do not. Beyond 8 weeks, age, establishment size and, to a lesser degree, wage compensation rate predict duration of work disability. Graphs show the predicted disability course for injured workers with specific covariate patterns. Future efforts to reduce missed worktime may require modifications in current clinical practice by patient age group and the development of new strategies to encourage small and medium-size employers to find ways to return their injured employees to work sooner. Recent federal statutes covering disabled workers will only partially correct the strong effect of employer establishment size.

Work family balance, stress, and salivary cortisol in men and women academic physicians.

PubMed

Bergman, B; Ahmad, F; Stewart, D E

2008-01-01

The stress of medical practice has been recurrently studied, but work- and family-related determinants of health by gender remain under researched. To test the hypothesis that cortisol excretion would be affected by the perceived severity of total workload imbalance. By hierarchical regression analysis, the associations between work-family balance and diurnal salivary cortisol levels by sex in academic physicians (n = 40) were investigated. Men physicians reported more paid work hours per week than women physicians and women more time in childcare, but their total working hours were similar. Controlling for sex and age, the mean of the diurnal cortisol release was associated with a combined effect of sex and responsibility at home. When morning cortisol, sex, and children at home were held constant, cortisol levels in the evening were associated with responsibility at home without significant gender interaction. With increasing responsibility at home, women and men reacted differently with regard to cortisol responses over the day. However, in the evening, controlling for the morning cortisol, these gender differences were not as obvious. These findings highlight traditional gender patterns among both women and men physicians in the challenge of finding a balance between work and family.

Dopaminergic contributions to working memory-related brain activation in postmenopausal women

PubMed Central

Dumas, Julie A.; Filippi, Christopher G.; Newhouse, Paul A.; Naylor, Magdalena R.

2016-01-01

Objective The current study examined the effects of pharmacologic dopaminergic manipulations on working memory-related brain activation in postmenopausal women to further understand the neurochemistry underlying cognition after menopause. Method Eighteen healthy postmenopausal women, mean age 55.21 years, completed three study days with dopaminergic drug challenges during which they performed an fMRI visual verbal N-back test of working memory. Acute stimulation with 1.25 mg oral D2 agonist bromocriptine, acute blockade with 1.5 mg oral haloperidol, and matching placebo were administered randomly and blindly on three study days. Results We found that dopaminergic stimulation increased activation primarily in the posterior regions of the working memory network compared to dopaminergic blockade using a whole brain cluster-level corrected analysis. The dopaminergic medications did not affect working memory performance. Conclusions Patterns of increased BOLD signal activation after dopaminergic stimulation were found in this study in posterior brain regions with no effect on working memory performance. Further studies should examine specific dopaminergic contributions to brain functioning in healthy postmenopausal women in order to determine the effects of the increased brain activation on cognition and behavior. PMID:27676634

The Green Sahara: Climate Change, Hydrologic History and Human Occupation

NASA Technical Reports Server (NTRS)

Blom, Ronald G.; Farr, Tom G.; Feynmann, Joan; Ruzmaikin, Alexander; Paillou, Philippe

2009-01-01

Archaeology can provide insight into interactions of climate change and human activities in sensitive areas such as the Sahara, to the benefit of both disciplines. Such analyses can help set bounds on climate change projections, perhaps identify elements of tipping points, and provide constraints on models. The opportunity exists to more precisely constrain the relationship of natural solar and climate interactions, improving understanding of present and future anthropogenic forcing. We are beginning to explore the relationship of human occupation of the Sahara and long-term solar irradiance variations synergetic with changes in atmospheric-ocean circulation patterns. Archaeological and climate records for the last 12 K years are gaining adequate precision to make such comparisons possible. We employ a range of climate records taken over the globe (e.g. Antarctica, Greenland, Cariaco Basin, West African Ocean cores, records from caves) to identify the timing and spatial patterns affecting Saharan climate to compare with archaeological records. We see correlation in changing ocean temperature patterns approx. contemporaneous with drying of the Sahara approx. 6K years BP. The role of radar images and other remote sensing in this work includes providing a geographically comprehensive geomorphic overview of this key area. Such coverage is becoming available from the Japanese PALSAR radar system, which can guide field work to collect archaeological and climatic data to further constrain the climate change chronology and link to models. Our initial remote sensing efforts concentrate on the Gilf Kebir area of Egypt.

Along fault friction and fluid pressure effects on the spatial distribution of fault-related fractures

NASA Astrophysics Data System (ADS)

Maerten, Laurent; Maerten, Frantz; Lejri, Mostfa

2018-03-01

Whatever the processes involved in the natural fracture development in the subsurface, fracture patterns are often affected by the local stress field during propagation. This homogeneous or heterogeneous local stress field can be of mechanical and/or tectonic origin. In this contribution, we focus on the fracture-pattern development where active faults perturb the stress field, and are affected by fluid pressure and sliding friction along the faults. We analyse and geomechanically model two fractured outcrops in UK (Nash Point) and in France (Les Matelles). We demonstrate that the observed local radial joint pattern is best explained by local fluid pressure along the faults and that observed fracture pattern can only be reproduced when fault friction is very low (μ < 0.2). Additionally, in the case of sub-vertical faults, we emphasize that the far field horizontal stress ratio does not affect stress trajectories, or fracture patterns, unless fault normal displacement (dilation or contraction) is relatively large.

Full-Day or Half-Day Kindergarten? ERIC Digest.

ERIC Educational Resources Information Center

Rothenberg, Dianne

This ERIC Digest examines how changing family patterns have affected the full-day/half-day kindergarten issue, discussing why schools are currently considering alternative scheduling and describing the advantages and disadvantages of each type of program. The following changing family patterns affecting the choice of full-day kindergarten programs…

A fuzzy logic-based model for noise control at industrial workplaces.

PubMed

Aluclu, I; Dalgic, A; Toprak, Z F

2008-05-01

Ergonomics is a broad science encompassing the wide variety of working conditions that can affect worker comfort and health, including factors such as lighting, noise, temperature, vibration, workstation design, tool design, machine design, etc. This paper describes noise-human response and a fuzzy logic model developed by comprehensive field studies on noise measurements (including atmospheric parameters) and control measures. The model has two subsystems constructed on noise reduction quantity in dB. The first subsystem of the fuzzy model depending on 549 linguistic rules comprises acoustical features of all materials used in any workplace. Totally 984 patterns were used, 503 patterns for model development and the rest 481 patterns for testing the model. The second subsystem deals with atmospheric parameter interactions with noise and has 52 linguistic rules. Similarly, 94 field patterns were obtained; 68 patterns were used for training stage of the model and the rest 26 patterns for testing the model. These rules were determined by taking into consideration formal standards, experiences of specialists and the measurements patterns. The results of the model were compared with various statistics (correlation coefficients, max-min, standard deviation, average and coefficient of skewness) and error modes (root mean square error and relative error). The correlation coefficients were significantly high, error modes were quite low and the other statistics were very close to the data. This statement indicates the validity of the model. Therefore, the model can be used for noise control in any workplace and helpful to the designer in planning stage of a workplace.

Similar Running Economy With Different Running Patterns Along the Aerial-Terrestrial Continuum.

PubMed

Lussiana, Thibault; Gindre, Cyrille; Hébert-Losier, Kim; Sagawa, Yoshimasa; Gimenez, Philippe; Mourot, Laurent

2017-04-01

No unique or ideal running pattern is the most economical for all runners. Classifying the global running patterns of individuals into 2 categories (aerial and terrestrial) using the Volodalen method could permit a better understanding of the relationship between running economy (RE) and biomechanics. The main purpose was to compare the RE of aerial and terrestrial runners. Two coaches classified 58 runners into aerial (n = 29) or terrestrial (n = 29) running patterns on the basis of visual observations. RE, muscle activity, kinematics, and spatiotemporal parameters of both groups were measured during a 5-min run at 12 km/h on a treadmill. Maximal oxygen uptake (V̇O 2 max) and peak treadmill speed (PTS) were assessed during an incremental running test. No differences were observed between aerial and terrestrial patterns for RE, V̇O 2 max, and PTS. However, at 12 km/h, aerial runners exhibited earlier gastrocnemius lateralis activation in preparation for contact, less dorsiflexion at ground contact, higher coactivation indexes, and greater leg stiffness during stance phase than terrestrial runners. Terrestrial runners had more pronounced semitendinosus activation at the start and end of the running cycle, shorter flight time, greater leg compression, and a more rear-foot strike. Different running patterns were associated with similar RE. Aerial runners appear to rely more on elastic energy utilization with a rapid eccentric-concentric coupling time, whereas terrestrial runners appear to propel the body more forward rather than upward to limit work against gravity. Excluding runners with a mixed running pattern from analyses did not affect study interpretation.

The French 35-hour workweek: a wide-ranging social change.

PubMed

Prunier-Poulmaire, S; Gadbois, C

2001-12-01

The reduction of the legal working week to 35 hours in France has generated wide-ranging social change. We examine the resulting changes in working-time patterns as well as their repercussions on the use of the time gained and on the quality of life and health. To compensate the reduction in the length of the working week, companies have modified the working-time patterns, by extending operation time (shiftwork, atypical schedules) and by matching the on-site workforce to production requirements (flexible working hours). They have sought to make more efficient use of working time: job intensification or job compression. The effects on the off-the-job life and health are linked to the shiftwork and atypical schedules designed to increase the company's operating time, and adjustments to the company's need for flexibilization impose working time/free time patterns that are at odds with biological rhythms and social life patterns. Changes to working-time patterns have unexpected consequences for work organization: heightened difficulties for the individual and the crew. These changes may generate a range of health problems related to overwork and stress. The way some companies have adapted may call into question the usefulness of work done by employees, thus damaging their social identity and mental well-being.

Lifetime achievement patterns, retirement and life satisfaction of gifted aged women.

PubMed

Holahan, C K

1981-11-01

The relationship of lifetime achievement patterns and retirement to life satisfaction for gifted aging women was investigated. Participants were 352 women in Terman's study of the gifted who were surveyed in 1977 at a mean age of 66. Lifetime achievement pattern was defined by either homemaker, job, or career work history. Dependent variables included health, happiness, life satisfaction, work attitudes, ambitions and aspirations, and participation in leisure activities. Results showed variations on life satisfaction measures as a function of lifetime career, with job holders generally less satisfied. There was a significant interaction between marital status and work pattern on overall life satisfaction suggesting an additive negative effect on the older woman of loss of spouse and a work history of working for income alone. Activity involvement varied as a function of retirement status and was differentially related to life satisfaction as a function of retirement status and career pattern.

The Differential Effects of Regular Shift Work and Obstructive Sleep Apnea on Sleepiness, Mood and Neurocognitive Function.

PubMed

Cori, Jennifer M; Jackson, Melinda L; Barnes, Maree; Westlake, Justine; Emerson, Paul; Lee, Jacen; Galante, Rosa; Hayley, Amie; Wilsmore, Nicholas; Kennedy, Gerard A; Howard, Mark

2018-06-15

To assess whether poor sleep quality experienced by regular shift workers and individuals with obstructive sleep apnea (OSA) affects neurobehavioral function similarly, or whether the different etiologies have distinct patterns of impairment. Thirty-seven shift workers (> 24 hours after their last shift), 36 untreated patients with OSA, and 39 healthy controls underwent assessment of sleepiness (Epworth Sleepiness Scale [ESS]), mood (Beck Depression Index, State Trait Anxiety Inventory [STAI], Profile of Mood States), vigilance (Psychomotor Vigilance Task [PVT], Oxford Sleep Resistance Test [OSLER], driving simulation), neurocognitive function (Logical Memory, Trails Making Task, Digit Span Task, Victoria Stroop Test) and polysomnography. Sleepiness (ESS score; median, interquartile range) did not differ between the OSA (10.5, 6.3-14) and shift work (7, 5-11.5) groups, but both had significantly elevated scores relative to the control group (5, 3-6). State anxiety (STAI-S) was the only mood variable that differed significantly between the OSA (35, 29-43) and shift work (30, 24-33.5) groups, however both demonstrated several mood deficits relative to the control group. The shift work and control groups performed similarly on neurobehavioral tasks (simulated driving, PVT, OSLER and neurocognitive tests), whereas the OSA group performed worse. On the PVT, lapses were significantly greater for the OSA group (3, 2-6) than both the shift work (2, 0-3.5) and control (1, 0-4) groups. Shift workers and patients with OSA had similar sleepiness and mood deficits relative to healthy individuals. However, only the patients with OSA showed deficits on vigilance and neurocognitive function relative to healthy individuals. These findings suggest that distinct causes of sleep disturbance likely result in different patterns of neurobehavioral dysfunction. © 2018 American Academy of Sleep Medicine.

A Comparison of Work Health and Safety Incidents and Injuries in Part-Time and Full-Time Australian Army Personnel.

PubMed

McDonald, Dylan; Orr, Robin M; Pope, Rodney

2016-11-01

 Part-time personnel are an integral part of the Australian Army. With operational deployments increasing, it is essential that medical teams identify the patterns of injuries sustained by part-time personnel in order to mitigate the risks of injury and optimize deployability.  To compare the patterns of reported work health and safety incidents and injuries in part-time and full-time Australian Army personnel.  Retrospective cohort study.  The Australian Army.  Australian Army Reserve and Australian regular Army populations, July 1, 2012, through June 30, 2014.  Proportions of reported work health and safety incidents that resulted in injuries among Army Reserve and regular Army personnel and specifically the (a) body locations affected by incidents, (b) nature of resulting injuries, (c) injury mechanisms, and (d) activities being performed when the incidents occurred.  Over 2 years, 15 065 work health and safety incidents and 11 263 injuries were reported in Army Reserve and regular Army populations combined. In the Army Reserve population, 85% of reported incidents were classified as involving minor personal injuries; 4% involved a serious personal injury. In the regular Army population, 68% of reported incidents involved a minor personal injury; 5% involved a serious personal injury. Substantially lower proportions of Army reservist incidents involved sports, whereas substantially higher proportions were associated with combat training, manual handling, and patrolling when compared with regular Army incidents.  Army reservists had a higher proportion of injuries from Army work-related activities than did regular Army soldiers. Proportions of incidents arising from combat tasks and manual handling were higher in the Army Reserve. Understanding the sources of injuries will allow the medical teams to implement injury-mitigation strategies.

A Comparison of Work Health and Safety Incidents and Injuries in Part-Time and Full-Time Australian Army Personnel

PubMed Central

McDonald, Dylan; Orr, Robin M.; Pope, Rodney

2016-01-01

Context: Part-time personnel are an integral part of the Australian Army. With operational deployments increasing, it is essential that medical teams identify the patterns of injuries sustained by part-time personnel in order to mitigate the risks of injury and optimize deployability. Objective: To compare the patterns of reported work health and safety incidents and injuries in part-time and full-time Australian Army personnel. Design: Retrospective cohort study. Setting: The Australian Army. Patients or Other Participants: Australian Army Reserve and Australian regular Army populations, July 1, 2012, through June 30, 2014. Main Outcome Measure(s): Proportions of reported work health and safety incidents that resulted in injuries among Army Reserve and regular Army personnel and specifically the (a) body locations affected by incidents, (b) nature of resulting injuries, (c) injury mechanisms, and (d) activities being performed when the incidents occurred. Results: Over 2 years, 15 065 work health and safety incidents and 11 263 injuries were reported in Army Reserve and regular Army populations combined. In the Army Reserve population, 85% of reported incidents were classified as involving minor personal injuries; 4% involved a serious personal injury. In the regular Army population, 68% of reported incidents involved a minor personal injury; 5% involved a serious personal injury. Substantially lower proportions of Army reservist incidents involved sports, whereas substantially higher proportions were associated with combat training, manual handling, and patrolling when compared with regular Army incidents. Conclusions: Army reservists had a higher proportion of injuries from Army work-related activities than did regular Army soldiers. Proportions of incidents arising from combat tasks and manual handling were higher in the Army Reserve. Understanding the sources of injuries will allow the medical teams to implement injury-mitigation strategies. PMID:27710093

Personnel resources in physical therapy: an analysis of supply, career patterns, and methods to enhance availability.

PubMed

Gwyer, J

1995-01-01

Describing the ever-changing supply and demand for physical therapy personnel in the United States is an intricate, complex, and profoundly significant task for the profession. In this article, a review of data relating to the supply of physical therapy personnel in the work force and their typical career patterns is presented. The estimates of the numbers of physical therapists and physical therapist assistants are discussed, as are problems associated with such estimates. Studies of career patterns of physical therapists are compared. Changes in the participation rates of women in the physical therapy work force over the last three decades are described. Career expectations, defined as both length and pattern of work-force participation, of entering physical therapy professionals are presented. Strategies to adjust the work-force participation of personnel through changes in the educational process, career patterns, and practice patterns are discussed.

Decreasing stochasticity through enhanced seasonality in measles epidemics.

PubMed

Mantilla-Beniers, N B; Bjørnstad, O N; Grenfell, B T; Rohani, P

2010-05-06

Seasonal changes in the environment are known to be important drivers of population dynamics, giving rise to sustained population cycles. However, it is often difficult to measure the strength and shape of seasonal forces affecting populations. In recent years, statistical time-series methods have been applied to the incidence records of childhood infectious diseases in an attempt to estimate seasonal variation in transmission rates, as driven by the pattern of school terms. In turn, school-term forcing was used to show how susceptible influx rates affect the interepidemic period. In this paper, we document the response of measles dynamics to distinct shifts in the parameter regime using previously unexplored records of measles mortality from the early decades of the twentieth century. We describe temporal patterns of measles epidemics using spectral analysis techniques, and point out a marked decrease in birth rates over time. Changes in host demography alone do not, however, suffice to explain epidemiological transitions. By fitting the time-series susceptible-infected-recovered model to measles mortality data, we obtain estimates of seasonal transmission in different eras, and find that seasonality increased over time. This analysis supports theoretical work linking complex population dynamics and the balance between stochastic and deterministic forces as determined by the strength of seasonality.

Improvement of resist profile roughness in bilayer resist process

NASA Astrophysics Data System (ADS)

Jeong, Chang-Young; Ryu, Sang-Wook; Park, Ki-Yeop; Lee, Won-Kyu; Lee, Seung-Woog; Lee, Dai-Hoon

2000-06-01

The bi-layer resist (BLR) process, which first accomplish imaging on a thin top layer and transfer it down to a thick organic layer, is one of newly emerging patterning techniques in silicon processing. In this work, we studied the lithographic performance of the BLR process adopting FK- SPTM (Fujifilm Olin Co.) as top layer material and various organic material as bottom layer. Generally, considerable advantages of planarization, reduced substrate reflection, improved process latitude, and of enhanced resolution are achieved. However, the resolution and the process latitude are highly affected by surface interaction between the top resist and the bottom material. Moreover, the BLR process has a sidewall roughness problem related to the material factors of the resist and the degraded aerial image contrast, which can affect the reliability of the device. We found that thermal curing treatment applied after development with the consideration of the glass transition temperature are very effective in reducing the line edge roughness. More smooth and steep patterning is achieved by the thermal treatment. The linewidth controllability is below 10 nm and the k1 value is reduced from 0.5 down to 0.32 in this process. The reactive ion etching adopting O2 gas demonstrated selectivity of the top resist over bottom material more than 15:1, together with residue-free and vertical wall profile.

Effect of nonlinearity on lesion formation for high-intensity focused ultrasound (HIFU) exposures

NASA Astrophysics Data System (ADS)

Lee, Paul; Lizzi, Frederic L.; Ketterling, Jeffrey A.; Vecchio, Christopher J.

2004-05-01

This study examined the effects of nonlinear propagation phenomena on two types of HIFU transducers (5 MHz) being used for thermal treatments of disease. The first transducer is a 5-element annular array. The second is a transducer with a 5-strip electrode; its multilobed focused beam is designed to efficiently produce broad, paddle-shaped lesions. The beam patterns of these transducers were computed using a variety of excitation patterns for electronic focusing of the annular array and variation of lesion size for the strip-electrode transducer. A range of intensities was studied to determine how nonlinear propagation affects the beam shape, constituent frequency content, grating lobes, etc. These 3D computations used a finite-amplitude beam propagation model that combined the angular spectrum method and Burger's equation to compute the diffraction and nonlinear effects, respectively. Computed beam patterns were compared with hydrophone measurements for each transducer. The linear and nonlinear beam patterns were used to compute the absorbed thermal dose, and the bioheat equation was evaluated to calculate 3D temperature rises and geometry of induced lesions. Computed lesion sizes and shapes were compared to in vitro lesions created by each HIFU transducer. [Work supported by NCI and NHLBI Grant 5R01 CA84588.

Spatial anxiety relates to spatial abilities as a function of working memory in children.

PubMed

Ramirez, Gerardo; Gunderson, Elizabeth A; Levine, Susan C; Beilock, Sian L

2012-01-01

Spatial ability is a strong predictor of students' pursuit of higher education in science and mathematics. However, very little is known about the affective factors that influence individual differences in spatial ability, particularly at a young age. We examine the role of spatial anxiety in young children's performance on a mental rotation task. We show that even at a young age, children report experiencing feelings of nervousness at the prospect of engaging in spatial activities. Moreover, we show that these feelings are associated with reduced mental rotation ability among students with high but not low working memory (WM). Interestingly, this WM × spatial anxiety interaction was only found among girls. We discuss these patterns of results in terms of the problem-solving strategies that boys versus girls use in solving mental rotation problems.

Disentangling dynamic networks: Separated and joint expressions of functional connectivity patterns in time.

PubMed

Leonardi, Nora; Shirer, William R; Greicius, Michael D; Van De Ville, Dimitri

2014-12-01

Resting-state functional connectivity (FC) is highly variable across the duration of a scan. Groups of coevolving connections, or reproducible patterns of dynamic FC (dFC), have been revealed in fluctuating FC by applying unsupervised learning techniques. Based on results from k-means clustering and sliding-window correlations, it has recently been hypothesized that dFC may cycle through several discrete FC states. Alternatively, it has been proposed to represent dFC as a linear combination of multiple FC patterns using principal component analysis. As it is unclear whether sparse or nonsparse combinations of FC patterns are most appropriate, and as this affects their interpretation and use as markers of cognitive processing, the goal of our study was to evaluate the impact of sparsity by performing an empirical evaluation of simulated, task-based, and resting-state dFC. To this aim, we applied matrix factorizations subject to variable constraints in the temporal domain and studied both the reproducibility of ensuing representations of dFC and the expression of FC patterns over time. During subject-driven tasks, dFC was well described by alternating FC states in accordance with the nature of the data. The estimated FC patterns showed a rich structure with combinations of known functional networks enabling accurate identification of three different tasks. During rest, dFC was better described by multiple FC patterns that overlap. The executive control networks, which are critical for working memory, appeared grouped alternately with externally or internally oriented networks. These results suggest that combinations of FC patterns can provide a meaningful way to disentangle resting-state dFC. © 2014 The Authors. Human Brain Mapping published by Wiley Periodicals, Inc.

Work disability remains a major problem in rheumatoid arthritis in the 2000s: data from 32 countries in the QUEST-RA study.

PubMed

Sokka, Tuulikki; Kautiainen, Hannu; Pincus, Theodore; Verstappen, Suzanne M M; Aggarwal, Amita; Alten, Rieke; Andersone, Daina; Badsha, Humeira; Baecklund, Eva; Belmonte, Miguel; Craig-Müller, Jürgen; da Mota, Licia Maria Henrique; Dimic, Alexander; Fathi, Nihal A; Ferraccioli, Gianfranco; Fukuda, Wataru; Géher, Pál; Gogus, Feride; Hajjaj-Hassouni, Najia; Hamoud, Hisham; Haugeberg, Glenn; Henrohn, Dan; Horslev-Petersen, Kim; Ionescu, Ruxandra; Karateew, Dmitry; Kuuse, Reet; Laurindo, Ieda Maria Magalhaes; Lazovskis, Juris; Luukkainen, Reijo; Mofti, Ayman; Murphy, Eithne; Nakajima, Ayako; Oyoo, Omondi; Pandya, Sapan C; Pohl, Christof; Predeteanu, Denisa; Rexhepi, Mjellma; Rexhepi, Sylejman; Sharma, Banwari; Shono, Eisuke; Sibilia, Jean; Sierakowski, Stanislaw; Skopouli, Fotini N; Stropuviene, Sigita; Toloza, Sergio; Valter, Ivo; Woolf, Anthony; Yamanaka, Hisashi

2010-01-01

Work disability is a major consequence of rheumatoid arthritis (RA), associated not only with traditional disease activity variables, but also more significantly with demographic, functional, occupational, and societal variables. Recent reports suggest that the use of biologic agents offers potential for reduced work disability rates, but the conclusions are based on surrogate disease activity measures derived from studies primarily from Western countries. The Quantitative Standard Monitoring of Patients with RA (QUEST-RA) multinational database of 8,039 patients in 86 sites in 32 countries, 16 with high gross domestic product (GDP) (>24K US dollars (USD) per capita) and 16 low-GDP countries (<11K USD), was analyzed for work and disability status at onset and over the course of RA and clinical status of patients who continued working or had stopped working in high-GDP versus low-GDP countries according to all RA Core Data Set measures. Associations of work disability status with RA Core Data Set variables and indices were analyzed using descriptive statistics and regression analyses. At the time of first symptoms, 86% of men (range 57%-100% among countries) and 64% (19%-87%) of women <65 years were working. More than one third (37%) of these patients reported subsequent work disability because of RA. Among 1,756 patients whose symptoms had begun during the 2000s, the probabilities of continuing to work were 80% (95% confidence interval (CI) 78%-82%) at 2 years and 68% (95% CI 65%-71%) at 5 years, with similar patterns in high-GDP and low-GDP countries. Patients who continued working versus stopped working had significantly better clinical status for all clinical status measures and patient self-report scores, with similar patterns in high-GDP and low-GDP countries. However, patients who had stopped working in high-GDP countries had better clinical status than patients who continued working in low-GDP countries. The most significant identifier of work disability in all subgroups was Health Assessment Questionnaire (HAQ) functional disability score. Work disability rates remain high among people with RA during this millennium. In low-GDP countries, people remain working with high levels of disability and disease activity. Cultural and economic differences between societies affect work disability as an outcome measure for RA.

Work disability remains a major problem in rheumatoid arthritis in the 2000s: data from 32 countries in the QUEST-RA Study

PubMed Central

2010-01-01

Introduction Work disability is a major consequence of rheumatoid arthritis (RA), associated not only with traditional disease activity variables, but also more significantly with demographic, functional, occupational, and societal variables. Recent reports suggest that the use of biologic agents offers potential for reduced work disability rates, but the conclusions are based on surrogate disease activity measures derived from studies primarily from Western countries. Methods The Quantitative Standard Monitoring of Patients with RA (QUEST-RA) multinational database of 8,039 patients in 86 sites in 32 countries, 16 with high gross domestic product (GDP) (>24K US dollars (USD) per capita) and 16 low-GDP countries (<11K USD), was analyzed for work and disability status at onset and over the course of RA and clinical status of patients who continued working or had stopped working in high-GDP versus low-GDP countries according to all RA Core Data Set measures. Associations of work disability status with RA Core Data Set variables and indices were analyzed using descriptive statistics and regression analyses. Results At the time of first symptoms, 86% of men (range 57%-100% among countries) and 64% (19%-87%) of women <65 years were working. More than one third (37%) of these patients reported subsequent work disability because of RA. Among 1,756 patients whose symptoms had begun during the 2000s, the probabilities of continuing to work were 80% (95% confidence interval (CI) 78%-82%) at 2 years and 68% (95% CI 65%-71%) at 5 years, with similar patterns in high-GDP and low-GDP countries. Patients who continued working versus stopped working had significantly better clinical status for all clinical status measures and patient self-report scores, with similar patterns in high-GDP and low-GDP countries. However, patients who had stopped working in high-GDP countries had better clinical status than patients who continued working in low-GDP countries. The most significant identifier of work disability in all subgroups was Health Assessment Questionnaire (HAQ) functional disability score. Conclusions Work disability rates remain high among people with RA during this millennium. In low-GDP countries, people remain working with high levels of disability and disease activity. Cultural and economic differences between societies affect work disability as an outcome measure for RA. PMID:20226018

Water, Carbon, and Nutrient Cycling Following Insect-induced Tree Mortality: How Well Do Plot-scale Observations Predict Ecosystem-Scale Response?

NASA Astrophysics Data System (ADS)

Brooks, P. D.; Barnard, H. R.; Biederman, J. A.; Borkhuu, B.; Edburg, S. L.; Ewers, B. E.; Gochis, D. J.; Gutmann, E. D.; Harpold, A. A.; Hicke, J. A.; Pendall, E.; Reed, D. E.; Somor, A. J.; Troch, P. A.

2011-12-01

Widespread tree mortality caused by insect infestations and drought has impacted millions of hectares across western North America in recent years. Although previous work on post-disturbance responses (e.g. experimental manipulations, fire, and logging) provides insight into how water and biogeochemical cycles may respond to insect infestations and drought, we find that the unique nature of these drivers of tree mortality complicates extrapolation to larger scales. Building from previous work on forest disturbance, we present a conceptual model of how temporal changes in forest structure impact the individual components of energy balance, hydrologic partitioning, and biogeochemical cycling and the interactions among them. We evaluate and refine this model using integrated observations and process modeling on multiple scales including plot, stand, flux tower footprint, hillslope, and catchment to identify scaling relationships and emergent patterns in hydrological and biogeochemical responses. Our initial results suggest that changes in forest structure at point or plot scales largely have predictable effects on energy, water, and biogeochemical cycles that are well captured by land surface, hydrological, and biogeochemical models. However, observations from flux towers and nested catchments suggest that both the hydrological and biogeochemical effects observed at tree and plot scales may be attenuated or exacerbated at larger scales. Compensatory processes are associated with attenuation (e.g. as transpiration decreases, evaporation and sublimation increase), whereas both attenuation and exacerbation may result from nonlinear scaling behavior across transitions in topography and ecosystem structure that affect the redistribution of energy, water, and solutes. Consequently, the effects of widespread tree mortality on ecosystem services of water supply and carbon sequestration will likely depend on how spatial patterns in mortality severity across the landscape affect large-scale hydrological partitioning.

Stress, burnout and depression: A systematic review on DNA methylation mechanisms.

PubMed

Bakusic, Jelena; Schaufeli, Wilmar; Claes, Stephan; Godderis, Lode

2017-01-01

Despite that burnout presents a serious burden for modern society, there are no diagnostic criteria. Additional difficulty is the differential diagnosis with depression. Consequently, there is a need to dispose of a burnout biomarker. Epigenetic studies suggest that DNA methylation is a possible mediator linking individual response to stress and psychopathology and could be considered as a potential biomarker of stress-related mental disorders. Thus, the aim of this review is to provide an overview of DNA methylation mechanisms in stress, burnout and depression. In addition to state-of-the-art overview, the goal of this review is to provide a scientific base for burnout biomarker research. We performed a systematic literature search and identified 25 pertinent articles. Among these, 15 focused on depression, 7 on chronic stress and only 3 on work stress/burnout. Three epigenome-wide studies were identified and the majority of studies used the candidate-gene approach, assessing 12 different genes. The glucocorticoid receptor gene (NR3C1) displayed different methylation patterns in chronic stress and depression. The serotonin transporter gene (SLC6A4) methylation was similarly affected in stress, depression and burnout. Work-related stress and depressive symptoms were associated with different methylation patterns of the brain derived neurotrophic factor gene (BDNF) in the same human sample. The tyrosine hydroxylase (TH) methylation was correlated with work stress in a single study. Additional, thoroughly designed longitudinal studies are necessary for revealing the cause-effect relationship of work stress, epigenetics and burnout, including its overlap with depression. Copyright © 2016 Elsevier Inc. All rights reserved.

[Work-related behaviour and experience patterns and mental health: a study in psychotherapy trainees].

PubMed

Grundmann, Johanna; Sude, Kerstin; Löwe, Bernd; Wingenfeld, Katja

2013-03-01

In view of the fact that many reports have been published that emphasize the difficult conditions of the German psychotherapy training, the aim of this study was to investigate psychotherapy trainees´ work stress as well as work-related psychosocial risks and resources. Variables of interest were work-related behaviour and experience patterns (AVEM), effort-reward-imbalance, chronic stress and health-related quality of life. 321 participants completed an online survey. The distribution of work-related behaviour and experience patterns as well as the results regarding work overload and mental health are evidence of psychotherapy trainees' strain. AVEM-risk patterns are associated with effort-reward-imbalance, chronic stress and reduced mental health. These results clearly support claims for a modification of the psychotherapy training in Germany. © Georg Thieme Verlag KG Stuttgart · New York.

An investigation of family environmental alteration affecting short-term recovery from Schizophrenia in China.

PubMed

Rong-Min Chen, R M

1995-02-01

It has been hypothesised that change in the family environment affects short-term recovery from schizophrenia. Observation and study of 210 schizophrenic patients who were influenced by family environmental alteration show that the prognosis of schizophrenia caused suddenly by family environmental alteration is better than that of schizophrenia caused by a persistently unfavourable family environment. Hence, we think sudden family environmental alterations do not cause psychorrhoea, but slow family environmental alteration may cause change in the mental state of patients. The prognosis is worse in the countryside than in the city. From the study group, we conclude that the first cure rate was 28%, and that 26% of patients were able to work. This indicates that there were no typical cases of the core pattern of schizophrenia, and that there was a certain potential for recovery. In the future, the emphasis of prevention and treatment must be placed on the countryside, and attention should be paid to the improvement of living and working conditions there, to the correct administration of patients, and to the improvement of recovery measures and therapy. We advocate that efforts should be made in the countryside to raise the national educational and cultural level.

Through the back door: nurse migration to the UK from Malawi and Nepal, a policy critique.

PubMed

Adhikari, Radha; Grigulis, Astrida

2014-03-01

The UK National Health Service has a long history of recruiting overseas nurses to meet nursing shortages in the UK. However, recruitment patterns regularly fluctuate in response to political and economic changes. Typically, the UK government gives little consideration of how these unstable recruitment practices affect overseas nurses. In this article, we present findings from two independent research studies from Malawi and Nepal, which aimed to examine how overseas nurses encountered and overcame the challenges linked to recent recruitment and migration restrictions. We show how current UK immigration policy has had a negative impact on overseas nurses' lives. It has led them to explore alternative entry routes into the UK, affecting both the quality of their working lives and their future decisions about whether to stay or return to their home country. We conclude that the shifting forces of nursing workforce demand and supply, leading to abrupt policy changes, have significant implications on overseas nurses' lives, and can leave nurses 'trapped' in the UK. We make recommendations for UK policy-makers to work with key stakeholders in nurse-sending countries to minimize the negative consequences of unstable nurse recruitment, and we highlight the benefits of promoting circular migration.

Patterns of admission to acute psychiatric in-patient facilities: a national survey in Italy.

PubMed

Preti, A; Rucci, P; Santone, G; Picardi, A; Miglio, R; Bracco, R; Norcio, B; de Girolamo, G

2009-03-01

A proper understanding of patterns of care represents a crucial step in improving clinical decision making and enhancing service provision. Only a few studies, however, have explored global patterns of psychiatric admissions nationwide, and none have been undertaken in Italy. Sociodemographic, clinical and treatment-related information was collected for 1577 patients admitted to 130 public and 36 private in-patient facilities in Italy during an index period in the year 2004. All patients were also rated using the 24-item Brief Psychiatric Rating Scale (BPRS) and the Personal and Social Performance (PSP) rating scales. Non-affective psychoses (36%) were the most common diagnoses and accounted to a large extent for compulsory admissions. Private facilities were more likely to admit patients with organic mental disorders and substance abuse/dependence and less likely to admit patients with non-affective psychoses. Overall, 77.8% of patients had been receiving treatment by a mental health professional in the month prior to admission. In 54% of cases, the admission was solicited by patients' family members. The main factors preceding admission were impairment in work or social functioning, social withdrawal, and conflict with family members. Agitation, delusions and/or hallucinations, and the presence of multiple problems were associated with compulsory admissions, whereas depressive and anxiety symptoms were associated with voluntary admissions. In a mixed, public-private psychiatric care system, like the Italian one, public and private facilities admit patients with widely different clinical characteristics and needs. Family support represents an important resource for most patients, and interventions specifically addressed to relieving family burden are warranted.

Factors affecting frequency and orbit utilization by high power transmission satellite systems.

NASA Technical Reports Server (NTRS)

Kuhns, P. W.; Miller, E. F.; O'Malley, T. A.

1972-01-01

The factors affecting the sharing of the geostationary orbit by high power (primarily television) satellite systems having the same or adjacent coverage areas and by satellites occupying the same orbit segment are examined and examples using the results of computer computations are given. The factors considered include: required protection ratio, receiver antenna patterns, relative transmitter power, transmitter antenna patterns, satellite grouping, and coverage pattern overlap. The results presented indicate the limits of system characteristics and orbit deployment which can result from mixing systems.

Factors affecting frequency and orbit utilization by high power transmission satellite systems

NASA Technical Reports Server (NTRS)

Kuhns, P. W.; Miller, E. F.; Malley, T. A.

1972-01-01

The factors affecting the sharing of the geostationary orbit by high power (primarily television) satellite systems having the same or adjacent coverage areas and by satellites occupying the same orbit segment are examined and examples using the results of computer computations are given. The factors considered include: required protection ratio, receiver antenna patterns, relative transmitter power, transmitter antenna patterns, satellite grouping, and coverage pattern overlap. The results presented indicated the limits of system characteristics and orbit deployment which can result from mixing systems.

Phylogenetic congruence of lichenised fungi and algae is affected by spatial scale and taxonomic diversity.

PubMed

Buckley, Hannah L; Rafat, Arash; Ridden, Johnathon D; Cruickshank, Robert H; Ridgway, Hayley J; Paterson, Adrian M

2014-01-01

The role of species' interactions in structuring biological communities remains unclear. Mutualistic symbioses, involving close positive interactions between two distinct organismal lineages, provide an excellent means to explore the roles of both evolutionary and ecological processes in determining how positive interactions affect community structure. In this study, we investigate patterns of co-diversification between fungi and algae for a range of New Zealand lichens at the community, genus, and species levels and explore explanations for possible patterns related to spatial scale and pattern, taxonomic diversity of the lichens considered, and the level sampling replication. We assembled six independent datasets to compare patterns in phylogenetic congruence with varied spatial extent of sampling, taxonomic diversity and level of specimen replication. For each dataset, we used the DNA sequences from the ITS regions of both the fungal and algal genomes from lichen specimens to produce genetic distance matrices. Phylogenetic congruence between fungi and algae was quantified using distance-based redundancy analysis and we used geographic distance matrices in Moran's eigenvector mapping and variance partitioning to evaluate the effects of spatial variation on the quantification of phylogenetic congruence. Phylogenetic congruence was highly significant for all datasets and a large proportion of variance in both algal and fungal genetic distances was explained by partner genetic variation. Spatial variables, primarily at large and intermediate scales, were also important for explaining genetic diversity patterns in all datasets. Interestingly, spatial structuring was stronger for fungal than algal genetic variation. As the spatial extent of the samples increased, so too did the proportion of explained variation that was shared between the spatial variables and the partners' genetic variation. Different lichen taxa showed some variation in their phylogenetic congruence and spatial genetic patterns and where greater sample replication was used, the amount of variation explained by partner genetic variation increased. Our results suggest that the phylogenetic congruence pattern, at least at small spatial scales, is likely due to reciprocal co-adaptation or co-dispersal. However, the detection of these patterns varies among different lichen taxa, across spatial scales and with different levels of sample replication. This work provides insight into the complexities faced in determining how evolutionary and ecological processes may interact to generate diversity in symbiotic association patterns at the population and community levels. Further, it highlights the critical importance of considering sample replication, taxonomic diversity and spatial scale in designing studies of co-diversification.

An Approach to In-Situ Observations of Volcanic Plumes

NASA Technical Reports Server (NTRS)

Smythe, W. D.; Lopes, M. C.; Pieri, D. C.; Hall, J. L.

2005-01-01

Volcanoes have long been recognized as playing a dominant role in the birth, and possibly the death, of biological populations. They are possible sources of primordial gases, provide conditions sufficient for creating amino acids, strongly affect the heat balance in the atmosphere, and have been shown to sustain life (in oceanic vents.) Eruptions can have profound effects on local flora and fauna, and for very large eruptions, may alter global weather patterns and cause entire species to fail. Measurements of particulates, gases, and dynamics within a volcanic plume are critical to understanding both how volcanoes work and how plumes affect populations, environment, and aviation. Volcanic plumes and associated eruption columns are a miasma of toxic gases, corrosive condensates, and abrasive particulates that makes them hazardous to nearby populations and poses a significant risk to all forms of aviation. Plumes also provide a mechanism for sampling the volcanic interior, which, for hydrothermal environments, may host unique biological populations.

Lowering social security's duration-of-marriage requirement: distributional effects for future female retirees.

PubMed

Tamborini, Christopher R; Whitman, Kevin

2010-01-01

A number of alternatives to Social Security's auxiliary benefit system have been proposed in the context of changes in American family and work patterns. This article focuses on one modification therein-lowering the 10-year duration-of-marriage requirement for divorced spouses. Using a powerful microsimulation model (MINT), we examine the distributional effects of extending spouse and survivor benefit eligibility to 5- and 7-year marriages ending in divorce among female retirees in 2030, a population largely comprised of baby boomers. Results show that the options would increase benefits for a small share of female retirees, around 2 to 4%, and would not affect the vast majority of low-income divorced older women. However, of those affected, the options would substantially increase benefits and lower incidence of poverty and near poor. Low-income divorced retirees with marriages between 5 and 9 years in length and a deceased former spouse face the greatest potential gains.

Grandchild, Grandparent, and Parent Coresidence from 1970 to 1990: Structural Factors Affecting State Patterns

ERIC Educational Resources Information Center

Hill, Twyla J.

2006-01-01

This study analyzes structural forces affecting state patterns of parental presence within grandparent-grandchild coresidence by testing demographic, social change, policy environment, and social problems models. The project combines published state-level data with the 1970, 1980, and 1990 Census Public Use Microdata Samples. While factors…

40 CFR 230.73 - Actions affecting the method of dispersion.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Actions To Minimize Adverse Effects § 230.73 Actions affecting the method of dispersion. The effects of a... obstruction to the water current or circulation pattern, and utilizing natural bottom contours to minimize the... patterns to mix, disperse and dilute the discharge; (e) Minimizing water column turbidity by using a...

40 CFR 230.73 - Actions affecting the method of dispersion.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Actions To Minimize Adverse Effects § 230.73 Actions affecting the method of dispersion. The effects of a... obstruction to the water current or circulation pattern, and utilizing natural bottom contours to minimize the... patterns to mix, disperse and dilute the discharge; (e) Minimizing water column turbidity by using a...

40 CFR 230.73 - Actions affecting the method of dispersion.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Actions To Minimize Adverse Effects § 230.73 Actions affecting the method of dispersion. The effects of a... obstruction to the water current or circulation pattern, and utilizing natural bottom contours to minimize the... patterns to mix, disperse and dilute the discharge; (e) Minimizing water column turbidity by using a...

40 CFR 230.73 - Actions affecting the method of dispersion.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Actions To Minimize Adverse Effects § 230.73 Actions affecting the method of dispersion. The effects of a... obstruction to the water current or circulation pattern, and utilizing natural bottom contours to minimize the... patterns to mix, disperse and dilute the discharge; (e) Minimizing water column turbidity by using a...

Judgments Relative to Patterns: How Temporal Sequence Patterns Affect Judgments and Memory

ERIC Educational Resources Information Center

Kusev, Petko; Ayton, Peter; van Schaik, Paul; Tsaneva-Atanasova, Krasimira; Stewart, Neil; Chater, Nick

2011-01-01

RESix experiments studied relative frequency judgment and recall of sequentially presented items drawn from 2 distinct categories (i.e., city and animal). The experiments show that judged frequencies of categories of sequentially encountered stimuli are affected by certain properties of the sequence configuration. We found (a) a "first-run…

The impact of negative emotions on self-concept abstraction depends on accessible information processing styles.

PubMed

Isbell, Linda M; Rovenpor, Daniel R; Lair, Elicia C

2016-10-01

Research suggests that anger promotes global, abstract processing whereas sadness and fear promote local, concrete processing (see Schwarz & Clore, 2007 for a review). Contrary to a large and influential body of work suggesting that specific affective experiences are tethered to specific cognitive outcomes, the affect-as-cognitive-feedback account maintains that affective experiences confer positive or negative value on currently dominant processing styles, and thus can lead to either global or local processing (Huntsinger, Isbell, & Clore, 2014). The current work extends this theoretical perspective by investigating the impact of discrete negative emotions on the self-concept. By experimentally manipulating information processing styles and discrete negative emotions that vary in appraisals of certainty, we demonstrate that the impact of discrete negative emotions on the spontaneous self-concept depends on accessible processing styles. When global processing was accessible, individuals in angry (negative, high certainty) states generated more abstract statements about themselves than individuals in either sad (Experiment 1) or fearful (Experiment 2; negative, low certainty) states. When local processing was made accessible, however, the opposite pattern emerged, whereby individuals in angry states generated fewer abstract statements than individuals in sad or fearful states. Together these studies provide new insights into the mechanisms through which discrete emotions influence cognition. In contrast to theories assuming a dedicated link between emotions and processing styles, these results suggest that discrete emotions provide feedback about accessible ways of thinking, and are consistent with recent evidence suggesting that the impact of affect on cognition is highly context-dependent. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Surveillance of work-related diseases by occupational physicians in the UK: OPRA 1996-1999.

PubMed

Cherry, N M; Meyer, J D; Holt, D L; Chen, Y; McDonald, J C

2000-09-01

The Occupational Physicians' Reporting Activity (OPRA) surveillance scheme for occupational physicians has now been in place for 4 years. During this period, an estimated 43,764 new cases of work-related disease have been reported. Musculoskeletal conditions make up nearly half (49%) of all cases; mental ill-health and skin disease account for 20% each, with respiratory conditions (8%) and hearing loss (5%) seen in lower proportions. Overall, eight of 42 diagnoses made up four-fifths of the new cases reported by occupational physicians. These were hand and arm disorders (8052 estimated cases), contact dermatitis (7104), disorders of the lumbar spine (6000), anxiety and depression (4788), work-related stress (3336), hearing loss (2100), elbow disorders (2040), and asthma (1680). Dermatitis and hearing loss were most frequent in manufacturing industries, lower back complaints in health care, and upper limb disorders in automotive manufacture. Psychiatric illnesses presented a different pattern, mainly affecting those in health, education and social service.

Patterning of physiological and affective responses in older active adults during a maximal graded exercise test and self-selected exercise.

PubMed

Smith, Ashleigh E; Eston, Roger; Tempest, Gavin D; Norton, Belinda; Parfitt, Gaynor

2015-09-01

The American College of Sports Medicine has highlighted the importance of considering the physiological and affective responses to exercise when setting exercise intensity. Here, we examined the relationship between exercise intensity and physiological and affective responses in active older adults. Eighteen participants (60-74 years; 64.4 ± 3.9; 8 women) completed a maximal graded exercise test (GXT) on a treadmill. Since time to exhaustion in the GXT differed between participants, heart rate (HR), oxygen consumption (VO2), affective valence (affect) and rating of perceived exertion (RPE) were expressed relative to the individually determined ventilatory threshold (%atVT). During the GXT, VO2, HR and RPE increased linearly (all P < 0.01). Affect declined initially (but remained positive) (P = 0.03), stabilised around VT (still positive) (P > 0.05) and became negative towards the end of the test (P < 0.01). In a subsequent session, participants completed a 20-min bout of self-selected exercise (at a preferred intensity). Initially, participants chose to exercise below VT (88.2 ± 17.4 %VO2atVT); however, the intensity was adjusted to work at, or above VT (107.7 ± 19.9 %VO2atVT) after 10 min (P < 0.001), whilst affect remained positive. Together, these findings indicate that exercise around VT, whether administered during an exercise test, or self-selected by the participant, is likely to result in positive affective responses in older adults.

Preference conditioning in healthy individuals: correlates with hazardous drinking.

PubMed

Balodis, Iris M; Lockwood, Kathleen P; Magrys, Sylvia A; Olmstead, Mary C

2010-06-01

Conditioned reward is a classic measure of drug-induced brain changes in animal models of addiction. The process can be examined in humans using the Conditioned Pattern Preference (CPP) task, in which participants associate nonverbal cues with reward but demonstrate low awareness of this conditioning. Previously, we reported that alcohol intoxication does not affect CPP acquisition in humans, but our data indicated that prior drug use may impact conditioning scores. To test this possibility, the current study examined the relationship between self-reported alcohol use and preference conditioning in the CPP task. Working memory was assessed during conditioning by asking participants to count the cues that appeared at each location on a computer screen. Participants (69 female and 23 male undergraduate students) completed the Alcohol Use Disorders Identification Test (AUDIT) and the Rutgers Alcohol Problem Index (RAPI) as measures of hazardous drinking. Self-reported hazardous drinking was significantly correlated with preference conditioning in that individuals who scored higher on these scales exhibited an increased preference for the reward-paired cues. In contrast, hazardous drinking did not affect working memory errors on the CPP task. These findings support evidence that repeated drug use sensitizes neural pathways mediating conditioned reward and point to a neurocognitive disposition linking substance misuse and responses to reward-paired stimuli. The relationship between hazardous drinking and conditioned reward is independent of changes in cognitive function, such as working memory.

The Dimensionality of Reasoning: Inductive and Deductive Inference can be Explained by a Single Process.

PubMed

Hayes, Brett K; Stephens, Rachel G; Ngo, Jeremy; Dunn, John C

2018-02-01

Three-experiments examined the number of qualitatively different processing dimensions needed to account for inductive and deductive reasoning. In each study, participants were presented with arguments that varied in logical validity and consistency with background knowledge (believability), and evaluated them according to deductive criteria (whether the conclusion was necessarily true given the premises) or inductive criteria (whether the conclusion was plausible given the premises). We examined factors including working memory load (Experiments 1 and 2), individual working memory capacity (Experiments 1 and 2), and decision time (Experiment 3), which according to dual-processing theories, modulate the contribution of heuristic and analytic processes to reasoning. A number of empirical dissociations were found. Argument validity affected deduction more than induction. Argument believability affected induction more than deduction. Lower working memory capacity reduced sensitivity to argument validity and increased sensitivity to argument believability, especially under induction instructions. Reduced decision time led to decreased sensitivity to argument validity. State-trace analyses of each experiment, however, found that only a single underlying dimension was required to explain patterns of inductive and deductive judgments. These results show that the dissociations, which have traditionally been seen as supporting dual-processing models of reasoning, are consistent with a single-process model that assumes a common evidentiary scale for induction and deduction. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

The combined influence of the main European circulation patterns on carbon uptake by ecosystems

NASA Astrophysics Data System (ADS)

Bastos, Ana; Gouveia, Célia; Trigo, Ricardo

2014-05-01

Understanding how natural climate variability affects carbon uptake by land and ocean pools is particularly relevant to better characterize human impact on the carbon cycle. Recently, we have contributed to assess the major role played by the El-Niño/Southern Oscillation in driving inter-annual variability (IAV) of carbon uptake by land ecosystems and significantly influencing global CO2 air-borne fraction [1]. Despite the prominent role played by ENSO, other important teleconnections on the hemispheric scale have deserved less attention. On the European scale, the main mode of variability is the North-Atlantic Oscillation (NAO), which controls storm tracks position and drives changes in temperature and precipitation over the whole region, affecting vegetation dynamics [2]. Besides NAO, a few additional large scale circulation patterns the Scandinavian (SC) and East-Atlantic (EA) Patterns, are also known to influence significantly the European climate [3]. Different combinations of these teleconnection polarities have been recently shown to modulate the overall role of the NAO impact location and strength, thus affecting winter temperature and precipitation patterns over Europe [4]. This work aims to answer the following questions: (i) how do NAO, EA and SC affect vegetation carbon uptake IAV? (ii) do the interactions between these three modes have a significant impact on land CO2 IAV? (iii) what is the contribution of the different physical variables to ecosystems' response to these modes? (iv) how well do the state-of-the-art Earth System Models (ESMs) from CMIP5 represent these climate variability modes and the corresponding carbon fluxes? We first analyze observational data to assess the relationships between the different combinations of NAO, SC and EA polarities and IAV of gross and net primary production (GPP and NPP, respectively), as well as the most relevant driving factors of ecosystem's response to those variability patterns. Although the winter state of NAO has, as expected, the largest impact on European-wide carbon uptake patterns, the other modes appear to have a strong influence in particular regions, presenting overlapping effects with different signs which are due to differentiated responses to temperature and precipitation variability. We then rely on the historical experiment (CO2 concentration driven) of 12 ESMs from CMIP5 to assess the capability of those models to represent NAO, EA and SC patterns, the associated physical variables as well as the corresponding land carbon fluxes. Although all models simulate NAO reasonably well, and most represent EA and SC patterns satisfactorily, the response of the carbon cycle to these variability modes still needs further improvements. References [1] Bastos, A., Running, S. W., Gouveia, C.M., Trigo, R.M., (2013): J. Geophys. Res. Biogeosci.,118, 1247-1255, doi:10.1002/jgrg.20100. [2] Gouveia, C.M., Trigo, R. M., DaCamara, C. C., Libonati, R., Pereira, J. M. C. (2008): Int. J. Climatol., 28, 1835-1847, doi: 10.1002/joc.1682. [3] Trigo R.M., Valente M.A., Trigo I.F., Miranda P.M., Ramos A.M., Paredes D., García-Herrera R. (2008): Annals of the New York Academy of Sciences, 1146, 212-234, doi: 10.1196/annals.1446.014. [4] Comas-Bru, L., McDermott, F. (2013): Q.J.R. Meteorol. Soc., doi: 10.1002/qj.2158.

Activity Patterns in Response to Symptoms in Patients Being Treated for Chronic Fatigue Syndrome: An Experience Sampling Methodology Study

PubMed Central

2016-01-01

Objective: Cognitive–behavioral models of chronic fatigue syndrome (CFS) propose that patients respond to symptoms with 2 predominant activity patterns—activity limitation and all-or-nothing behaviors—both of which may contribute to illness persistence. The current study investigated whether activity patterns occurred at the same time as, or followed on from, patient symptom experience and affect. Method: Twenty-three adults with CFS were recruited from U.K. CFS services. Experience sampling methodology (ESM) was used to assess fluctuations in patient symptom experience, affect, and activity management patterns over 10 assessments per day for a total of 6 days. Assessments were conducted within patients’ daily life and were delivered through an app on touchscreen Android mobile phones. Multilevel model analyses were conducted to examine the role of self-reported patient fatigue, pain, and affect as predictors of change in activity patterns at the same and subsequent assessment. Results: Current experience of fatigue-related symptoms and pain predicted higher patient activity limitation at the current and subsequent assessments whereas subjective wellness predicted higher all-or-nothing behavior at both times. Current pain predicted less all-or-nothing behavior at the subsequent assessment. In contrast to hypotheses, current positive affect was predictive of current activity limitation whereas current negative affect was predictive of current all-or-nothing behavior. Both activity patterns varied at the momentary level. Conclusions: Patient symptom experiences appear to be driving patient activity management patterns in line with the cognitive–behavioral model of CFS. ESM offers a useful method for examining multiple interacting variables within the context of patients’ daily life. PMID:27819461

What I experienced yesterday is who I am today: relationship of work motivations and behaviors to within-individual variation in the five-factor model of personality.

PubMed

Judge, Timothy A; Simon, Lauren S; Hurst, Charlice; Kelley, Ken

2014-03-01

Historically, organizational and personality psychologists have ignored within-individual variation in personality across situations or have treated it as measurement error. However, we conducted a 10-day experience sampling study consistent with whole trait theory (Fleeson, 2012), which conceptualizes personality as a system of stable tendencies and patterns of intraindividual variation along the dimensions of the Big Five personality traits (Costa & McCrae, 1992). The study examined whether (a) internal events (i.e., motivation), performance episodes, and interpersonal experiences at work predict deviations from central tendencies in trait-relevant behavior, affect, and cognition (i.e., state personality), and (b) there are individual differences in responsiveness to work experiences. Results revealed that personality at work exhibited both stability and variation within individuals. Trait measures predicted average levels of trait manifestation in daily behavior at work, whereas daily work experiences (i.e., organizational citizenship, interpersonal conflict, and motivation) predicted deviations from baseline tendencies. Additionally, correlations of neuroticism with standard deviations in the daily personality variables suggest that, although work experiences influence state personality, people higher in neuroticism exhibit higher levels of intraindividual variation in personality than do those who are more emotionally stable.

Stress Reactivity in Traditional Chinese Medicine–Based Subgroups of Patients with Irritable Bowel Syndrome

PubMed Central

Chang, Megan C.; Shapiro, David; Joshi, Aditi; Shahabi, Leila; Tan, Steven; Smith, Suzanne; Hui, Ka Kit; Tillisch, Kirsten; Mayer, Emeran A.

2014-01-01

Abstract Objectives: This study aimed to examine differences in autonomic responses to stress, pain perception, and the role of negative affect in these responses in individuals with irritable bowel syndrome (IBS) according to Traditional Chinese Medicine (TCM) classifications. Design: Fifty-nine female patients with IBS age 18–65 years diagnosed by TCM practitioners as showing primarily an excess (n=32) or an overlap (n=27) pattern (mixed excess and deficiency) were assessed for symptom differences, heart rate, and skin conductance responses to a psychosocial stressor and pain perception. Settings/Locations: University of California in Los Angeles, California. Results: Compared with the excess group, the overlap group showed significantly greater overall gastrointestinal symptom severity, abdominal pain, and negative affect. The excess group with higher levels of negative affect showed greater reactivity to stress, whereas the overlap group showed an opposite response pattern. The overlap group showed increased cold sensitivity. Conclusions: IBS patients with the overlap pattern have greater disease severity and comorbidity than those with excess alone. Those with excess showed a pattern of increased stress response with greater negative affect, whereas the overlap group with greater deficiency showed lower physiologic arousal with greater negative affect, consistent with depletion resulting from allostatic load. PMID:24256027

Multivariate pattern classification reveals autonomic and experiential representations of discrete emotions.

PubMed

Kragel, Philip A; Labar, Kevin S

2013-08-01

Defining the structural organization of emotions is a central unresolved question in affective science. In particular, the extent to which autonomic nervous system activity signifies distinct affective states remains controversial. Most prior research on this topic has used univariate statistical approaches in attempts to classify emotions from psychophysiological data. In the present study, electrodermal, cardiac, respiratory, and gastric activity, as well as self-report measures were taken from healthy subjects during the experience of fear, anger, sadness, surprise, contentment, and amusement in response to film and music clips. Information pertaining to affective states present in these response patterns was analyzed using multivariate pattern classification techniques. Overall accuracy for classifying distinct affective states was 58.0% for autonomic measures and 88.2% for self-report measures, both of which were significantly above chance. Further, examining the error distribution of classifiers revealed that the dimensions of valence and arousal selectively contributed to decoding emotional states from self-report, whereas a categorical configuration of affective space was evident in both self-report and autonomic measures. Taken together, these findings extend recent multivariate approaches to study emotion and indicate that pattern classification tools may improve upon univariate approaches to reveal the underlying structure of emotional experience and physiological expression. PsycINFO Database Record (c) 2013 APA, all rights reserved.

Multivariate Pattern Classification Reveals Autonomic and Experiential Representations of Discrete Emotions

PubMed Central

Kragel, Philip A.; LaBar, Kevin S.

2013-01-01

Defining the structural organization of emotions is a central unresolved question in affective science. In particular, the extent to which autonomic nervous system activity signifies distinct affective states remains controversial. Most prior research on this topic has used univariate statistical approaches in attempts to classify emotions from psychophysiological data. In the present study, electrodermal, cardiac, respiratory, and gastric activity, as well as self-report measures were taken from healthy subjects during the experience of fear, anger, sadness, surprise, contentment, and amusement in response to film and music clips. Information pertaining to affective states present in these response patterns was analyzed using multivariate pattern classification techniques. Overall accuracy for classifying distinct affective states was 58.0% for autonomic measures and 88.2% for self-report measures, both of which were significantly above chance. Further, examining the error distribution of classifiers revealed that the dimensions of valence and arousal selectively contributed to decoding emotional states from self-report, whereas a categorical configuration of affective space was evident in both self-report and autonomic measures. Taken together, these findings extend recent multivariate approaches to study emotion and indicate that pattern classification tools may improve upon univariate approaches to reveal the underlying structure of emotional experience and physiological expression. PMID:23527508

Young Children’s Affective Responses to Another’s Distress: Dynamic and Physiological Features

PubMed Central

Fink, Elian; Heathers, James A. J.; de Rosnay, Marc

2015-01-01

Two descriptive studies set out a new approach for exploring the dynamic features of children’s affective responses (sadness and interest-worry) to another’s distress. In two samples (N study1 = 75; N study2 = 114), Kindergarten children were shown a video-vignette depicting another child in distress and the temporal pattern of spontaneous expressions were examined across the unfolding vignette. Results showed, in both study 1 and 2, that sadness and interest-worry had distinct patterns of elicitation across the events of the vignette narrative and there was little co-occurrence of these affects within a given child. Temporal heart rate changes (study 2) were closely aligned to the events of the vignette and, furthermore, affective responses corresponded to distinctive physiological response profiles. The implications of distinct temporal patterns of elicitation for the meaning of sadness and interest-worry are discussed within the framework of emotion regulation and empathy. PMID:25874952

Teenage goals and self-efficacy beliefs as precursors of adult career and family outcomes

PubMed Central

Lee, Bora; Vondracek, Fred W.

2014-01-01

The present study identified and examined patterns of goal importance and self-efficacy beliefs in mid- and late adolescence as predictors of work and family outcomes in adulthood. A pattern approach was applied to appropriately identify relationships among work- and family-related goal importance and self-efficacy beliefs. Using a sample of 995 individuals, five distinct patterns of work-family goal importance and self-efficacy beliefs emerged. Individuals who assigned comparable importance to work and family goals and expressed corresponding self-efficacy beliefs in adolescence were more likely to achieve career and family outcomes in adulthood than individuals who expressed a strong preference for one domain over the other. The results supported the idea that work and family can be coordinated for mutual benefit. Furthermore, findings from the pattern approach provided an integrative view of work-family motivation and goal achievement complementing findings from traditional methods such as regression analysis. PMID:25242815

Teenage goals and self-efficacy beliefs as precursors of adult career and family outcomes.

PubMed

Lee, Bora; Vondracek, Fred W

2014-10-01

The present study identified and examined patterns of goal importance and self-efficacy beliefs in mid- and late adolescence as predictors of work and family outcomes in adulthood. A pattern approach was applied to appropriately identify relationships among work- and family-related goal importance and self-efficacy beliefs. Using a sample of 995 individuals, five distinct patterns of work-family goal importance and self-efficacy beliefs emerged. Individuals who assigned comparable importance to work and family goals and expressed corresponding self-efficacy beliefs in adolescence were more likely to achieve career and family outcomes in adulthood than individuals who expressed a strong preference for one domain over the other. The results supported the idea that work and family can be coordinated for mutual benefit. Furthermore, findings from the pattern approach provided an integrative view of work-family motivation and goal achievement complementing findings from traditional methods such as regression analysis.

Electrode replacement does not affect classification accuracy in dual-session use of a passive brain-computer interface for assessing cognitive workload

PubMed Central

Estepp, Justin R.; Christensen, James C.

2015-01-01

The passive brain-computer interface (pBCI) framework has been shown to be a very promising construct for assessing cognitive and affective state in both individuals and teams. There is a growing body of work that focuses on solving the challenges of transitioning pBCI systems from the research laboratory environment to practical, everyday use. An interesting issue is what impact methodological variability may have on the ability to reliably identify (neuro)physiological patterns that are useful for state assessment. This work aimed at quantifying the effects of methodological variability in a pBCI design for detecting changes in cognitive workload. Specific focus was directed toward the effects of replacing electrodes over dual sessions (thus inducing changes in placement, electromechanical properties, and/or impedance between the electrode and skin surface) on the accuracy of several machine learning approaches in a binary classification problem. In investigating these methodological variables, it was determined that the removal and replacement of the electrode suite between sessions does not impact the accuracy of a number of learning approaches when trained on one session and tested on a second. This finding was confirmed by comparing to a control group for which the electrode suite was not replaced between sessions. This result suggests that sensors (both neurological and peripheral) may be removed and replaced over the course of many interactions with a pBCI system without affecting its performance. Future work on multi-session and multi-day pBCI system use should seek to replicate this (lack of) effect between sessions in other tasks, temporal time courses, and data analytic approaches while also focusing on non-stationarity and variable classification performance due to intrinsic factors. PMID:25805963

Electrode replacement does not affect classification accuracy in dual-session use of a passive brain-computer interface for assessing cognitive workload.

PubMed

Estepp, Justin R; Christensen, James C

2015-01-01

The passive brain-computer interface (pBCI) framework has been shown to be a very promising construct for assessing cognitive and affective state in both individuals and teams. There is a growing body of work that focuses on solving the challenges of transitioning pBCI systems from the research laboratory environment to practical, everyday use. An interesting issue is what impact methodological variability may have on the ability to reliably identify (neuro)physiological patterns that are useful for state assessment. This work aimed at quantifying the effects of methodological variability in a pBCI design for detecting changes in cognitive workload. Specific focus was directed toward the effects of replacing electrodes over dual sessions (thus inducing changes in placement, electromechanical properties, and/or impedance between the electrode and skin surface) on the accuracy of several machine learning approaches in a binary classification problem. In investigating these methodological variables, it was determined that the removal and replacement of the electrode suite between sessions does not impact the accuracy of a number of learning approaches when trained on one session and tested on a second. This finding was confirmed by comparing to a control group for which the electrode suite was not replaced between sessions. This result suggests that sensors (both neurological and peripheral) may be removed and replaced over the course of many interactions with a pBCI system without affecting its performance. Future work on multi-session and multi-day pBCI system use should seek to replicate this (lack of) effect between sessions in other tasks, temporal time courses, and data analytic approaches while also focusing on non-stationarity and variable classification performance due to intrinsic factors.

The influence of daily sleep patterns of commercial truck drivers on driving performance

PubMed Central

Chen, Guang Xiang; Fang, Youjia; Guo, Feng; Hanowski, Richard J.

2016-01-01

Fatigued and drowsy driving has been found to be a major cause of truck crashes. Lack of sleep is the number one cause of fatigue and drowsiness. However, there are limited data on the sleep patterns (sleep duration, sleep percentage in the duration of non-work period, and the time when sleep occurred) of truck drivers in non-work periods and the impact on driving performance. This paper examined sleep patterns of 96 commercial truck drivers during non-work periods and evaluated the influence these sleep patterns had on truck driving performance. Data were from the Naturalistic Truck Driving Study. Each driver participated in the study for approximately four weeks. A shift was defined as a non-work period followed by a work period. A total of 1397 shifts were identified. Four distinct sleep patterns were identified based on sleep duration, sleep start/end point in a non-work period, and the percentage of sleep with reference to the duration of non-work period. Driving performance was measured by safety-critical events, which included crashes, near-crashes, crash-relevant conflicts, and unintentional lane deviations. Negative binomial regression was used to evaluate the association between the sleep patterns and driving performance, adjusted for driver demographic information. The results showed that the sleep pattern with the highest safety-critical event rate was associated with shorter sleep, sleep in the early stage of a non-work period, and less sleep between 1 a.m. and 5 a.m. This study also found that male drivers, with fewer years of commercial vehicle driving experience and higher body mass index, were associated with deteriorated driving performance and increased driving risk. The results of this study could inform hours-of-service policy-making and benefit safety management in the trucking industry. PMID:26954762

The Impact of Negative Affect on Attention Patterns to Threat across the First 2 Years of Life

ERIC Educational Resources Information Center

Pérez-Edgar, Koraly; Morales, Santiago; LoBue, Vanessa; Taber-Thomas, Bradley C.; Allen, Elizabeth K.; Brown, Kayla M.; Buss, Kristin A.

2017-01-01

The current study examined the relations between individual differences in attention to emotion faces and temperamental negative affect across the first 2 years of life. Infant studies have noted a normative pattern of preferential attention to salient cues, particularly angry faces. A parallel literature suggests that elevated attention bias to…

Flight Attendant Fatigue Recommendation 2: Flight Attendant Work/Rest Patterns, Alertness, and Performance Assessment

DTIC Science & Technology

2010-12-01

Recommendation II: Flight Attendant Work/Rest Patterns, Alertness, and Performance Assessment DOT/FAA/AM-10/22 Office of Aerospace Medicine Washington, DC...Recipient’s Catalog No. DOT/FAA/AM-10/22 4. Title and Subtitle 5. Report Date December 2010 6. Performing Organization Code Flight...Attendant Fatigue Recommendation II: Flight Attendant Work/Rest Patterns, Alertness, and Performance Assessment 7. Author(s) 8. Performing

Telecommuting: An Altered Work Pattern.

DTIC Science & Technology

1984-09-01

TELECOMMUtTING : AN ALTERED WORK PATTERN THES IS Carole H. Smith GS -12 AFIT /GLMI/LSM/ 84S-59 Approved for public release; distribution unlimited__ , v 184...7 7.._._.._. _ ,:. . . 70-.--.- "" .._ 7." " --------- :’’ APIT/GLM/LSU/ 84s-59 TELECOMMUTING : AN ALTERED WORK PATTERN THES IS...Electronic Services Unlimited, a New York based telecommut - ing consultant company. They introduced me to telecommut - ing concepts in the private sector

Detection of Anomalies in Hydrometric Data Using Artificial Intelligence Techniques

NASA Astrophysics Data System (ADS)

Lauzon, N.; Lence, B. J.

2002-12-01

This work focuses on the detection of anomalies in hydrometric data sequences, such as 1) outliers, which are individual data having statistical properties that differ from those of the overall population; 2) shifts, which are sudden changes over time in the statistical properties of the historical records of data; and 3) trends, which are systematic changes over time in the statistical properties. For the purpose of the design and management of water resources systems, it is important to be aware of these anomalies in hydrometric data, for they can induce a bias in the estimation of water quantity and quality parameters. These anomalies may be viewed as specific patterns affecting the data, and therefore pattern recognition techniques can be used for identifying them. However, the number of possible patterns is very large for each type of anomaly and consequently large computing capacities are required to account for all possibilities using the standard statistical techniques, such as cluster analysis. Artificial intelligence techniques, such as the Kohonen neural network and fuzzy c-means, are clustering techniques commonly used for pattern recognition in several areas of engineering and have recently begun to be used for the analysis of natural systems. They require much less computing capacity than the standard statistical techniques, and therefore are well suited for the identification of outliers, shifts and trends in hydrometric data. This work constitutes a preliminary study, using synthetic data representing hydrometric data that can be found in Canada. The analysis of the results obtained shows that the Kohonen neural network and fuzzy c-means are reasonably successful in identifying anomalies. This work also addresses the problem of uncertainties inherent to the calibration procedures that fit the clusters to the possible patterns for both the Kohonen neural network and fuzzy c-means. Indeed, for the same database, different sets of clusters can be established with these calibration procedures. A simple method for analyzing uncertainties associated with the Kohonen neural network and fuzzy c-means is developed here. The method combines the results from several sets of clusters, either from the Kohonen neural network or fuzzy c-means, so as to provide an overall diagnosis as to the identification of outliers, shifts and trends. The results indicate an improvement in the performance for identifying anomalies when the method of combining cluster sets is used, compared with when only one cluster set is used.

A method of solving tilt illumination for multiple distance phase retrieval

NASA Astrophysics Data System (ADS)

Guo, Cheng; Li, Qiang; Tan, Jiubin; Liu, Shutian; Liu, Zhengjun

2018-07-01

Multiple distance phase retrieval is a technique of using a series of intensity patterns to reconstruct a complex-valued image of object. However, tilt illumination originating from the off-axis displacement of incident light significantly impairs its imaging quality. To eliminate this affection, we use cross-correlation calibration to estimate oblique angle of incident light and a Fourier-based strategy to correct tilted illumination effect. Compared to other methods, binary and biological object are both stably reconstructed in simulation and experiment. This work provides a simple but beneficial method to solve the problem of tilt illumination for lens-free multi-distance system.

Cross-language diversity, head-direction and grammars. Comment on "Dependency distance: A new perspective on syntactic patterns in natural languages" by Haitao Liu et al.

NASA Astrophysics Data System (ADS)

Hudson, Richard

2017-07-01

This paper [4] - referred to below as 'LXL' - is an excellent example of cross-disciplinary work which brings together three very different disciplines, each with its different methods: quantitative computational linguistics (exploring big data), psycholinguistics (using experiments with human subjects) and theoretical linguistics (building models based on language descriptions). The measured unit is the dependency between two words, as defined by theoretical linguistics, and the question is how the length of this dependency affects the choices made by writers, as revealed in big data from a wide range of languages.

Air-coupled ultrasonic sensing of grass-covered vibrating surfaces; qualitative comparisons with laser Doppler vibrometry

NASA Astrophysics Data System (ADS)

Petculescu, Andi G.; Sabatier, James M.

2004-04-01

The paper addresses several sensitive issues concerning the use of air-coupled ultrasound to probe small vibrations of surfaces covered with low-lying vegetation such as grass. The operation of the ultrasonic sensor is compared to that of a laser Doppler vibrometer, in various contexts. It is shown that ambient air motion affects either system, albeit differently. As air speed increases, the acoustic sensor detects a progressively richer turbulent spectrum, which reduces its sensitivity. In turn, optical sensors are prone to tremendous signal losses when probing moving vegetation, due to randomly varying speckle patterns. The work was supported by the Office of Naval Research.

Hair and Physiological Baldness

PubMed Central

Mercantini, Edward S.

1965-01-01

Human hair is one of the structures of the body about which little is generally known. Disease affecting the hair is often minimized or ignored by physicians because of lack of knowledge of this rudimentary organ. However, the patient's attitude toward hair loss is very different from the doctor's and he feels great concern about such loss. The development, growth and morphology of human hair are briefly presented. Experimental work which will increase our knowledge of hair growth and loss is reviewed. The various forms of physiological alopecia from birth onward are discussed, with special emphasis on the least-known type of physiological baldness, “male-pattern baldness” in the adult female. PMID:14312445

Thermal behaviour of nanofluids confined in nanochannels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frank, Michael, E-mail: d.drikakis@cranfield.ac.uk; Drikakis, Dimitris, E-mail: d.drikakis@cranfield.ac.uk; Asproulis, Nikolaos, E-mail: d.drikakis@cranfield.ac.uk

2015-02-17

This work investigates the effect of spatial restriction on the thermal properties of nanofluids. Using Molecular Dynamics simulations, a Copper-Argon nanofluid is restricted within idealized walls. The thermal conductivity of the suspension is calculated using the Green-Kubo relations and is correlated with the volume fraction of the copper particles within the system as well as the channel width. The thermal conductivity is further broken down into its individual components in the three dimensions, revealing anisotropy between the directions parallel and normal to the channel walls. The observed thermodynamic patterns are justified by considering how the spatial restriction affects the liquidmore » structure around the nanoparticle.« less

Global Symmetries of Naive and Staggered Fermions in Arbitrary Dimensions

NASA Astrophysics Data System (ADS)

Kieburg, Mario; Würfel, Tim R.

2018-03-01

It is well-known that staggered fermions do not necessarily satisfy the same global symmetries as the continuum theory. We analyze the mechanism behind this phenomenon for arbitrary dimension and gauge group representation. For this purpose we vary the number of lattice sites between even and odd parity in each single direction. Since the global symmetries are manifest in the lowest eigenvalues of the Dirac operator, the spectral statistics and also the symmetry breaking pattern will be affected. We analyze these effects and compare our predictions with Monte-Carlo simulations of naive Dirac operators in the strong coupling limit. This proceeding is a summary of our work [1].

Mathematical model for the assessment of fracture risk associated with osteoporosis

NASA Astrophysics Data System (ADS)

Dinis, Jairson; Pereira, Ana I.; Fonseca, Elza M.

2012-09-01

Osteoporosis is a skeletal disease characterized by low bone mass. It is considered a worldwide public health problem that affects a large number of people, in particularly for women with more than 50 years old. The occurrence pattern of osteoporosis in a population may be related to several factors, including socio-economic factors such as income, educational attainment, and factors related to lifestyle such as diet and physical activity. These and other aspects have increasingly been identified as determining the occurrence of various diseases, including osteoporosis. This work proposes a mathematical model that provides the level of osteoporosis in the patient. Preliminary numerical results are presented.

The neurobiology of psychopathy.

PubMed

Glenn, Andrea L; Raine, Adrian

2008-09-01

Numerous studies have tackled the complex challenge of understanding the neural substrates of psychopathy, revealing that brain abnormalities exist on several levels and in several structures. As we discover more about complex neural networks, it becomes increasingly difficult to clarify how these systems interact with each other to produce the distinct pattern of behavioral and personality characteristics observed in psychopathy. The authors review the recent research on the neurobiology of psychopathy, beginning with molecular neuroscience work and progressing to the level of brain structures and their connectivity. Potential factors that may affect the development of brain impairments, as well as how some systems may be targeted for potential treatment, are discussed.

Response to long-term growth hormone therapy in patients affected by RASopathies and growth hormone deficiency: Patterns of growth, puberty and final height data.

PubMed

Tamburrino, Federica; Gibertoni, Dino; Rossi, Cesare; Scarano, Emanuela; Perri, Annamaria; Montanari, Francesca; Fantini, Maria Pia; Pession, Andrea; Tartaglia, Marco; Mazzanti, Laura

2015-11-01

RASopathies are developmental disorders caused by heterozygous germline mutations in genes encoding proteins in the RAS-MAPK signaling pathway. Reduced growth is a common feature. Several studies generated data on growth, final height (FH), and height velocity (HV) after growth hormone (GH) treatment in patients with these disorders, particularly in Noonan syndrome, the most common RASopathy. These studies, however, refer to heterogeneous cohorts in terms of molecular information, GH status, age at start and length of therapy, and GH dosage. This work reports growth data in 88 patients affected by RASopathies with molecularly confirmed diagnosis, together with statistics on body proportions, pubertal pattern, and FH in 33, including 16 treated with GH therapy for proven GH deficiency. Thirty-three patients showed GH deficiency after pharmacological tests, and were GH-treated for an average period of 6.8 ± 4.8 years. Before starting therapy, HV was -2.6 ± 1.3 SDS, and mean basal IGF1 levels were -2.0 ± 1.1 SDS. Long-term GH therapy, starting early during childhood, resulted in a positive height response compared with untreated patients (1.3 SDS in terms of height-gain), normalizing FH for Ranke standards but not for general population and Target Height. Pubertal timing negatively affected pubertal growth spurt and FH, with IGF1 standardized score increased from -2.43 to -0.27 SDS. During GH treatment, no significant change in bone age velocity, body proportions, or cardiovascular function was observed. © 2015 Wiley Periodicals, Inc.

The relative effects of habitat loss and fragmentation on population genetic variation in the red-cockaded woodpecker (Picoides borealis).

PubMed

Bruggeman, Douglas J; Wiegand, Thorsten; Fernández, Néstor

2010-09-01

The relative influence of habitat loss, fragmentation and matrix heterogeneity on the viability of populations is a critical area of conservation research that remains unresolved. Using simulation modelling, we provide an analysis of the influence both patch size and patch isolation have on abundance, effective population size (N(e)) and F(ST). An individual-based, spatially explicit population model based on 15 years of field work on the red-cockaded woodpecker (Picoides borealis) was applied to different landscape configurations. The variation in landscape patterns was summarized using spatial statistics based on O-ring statistics. By regressing demographic and genetics attributes that emerged across the landscape treatments against proportion of total habitat and O-ring statistics, we show that O-ring statistics provide an explicit link between population processes, habitat area, and critical thresholds of fragmentation that affect those processes. Spatial distances among land cover classes that affect biological processes translated into critical scales at which the measures of landscape structure correlated best with genetic indices. Therefore our study infers pattern from process, which contrasts with past studies of landscape genetics. We found that population genetic structure was more strongly affected by fragmentation than population size, which suggests that examining only population size may limit recognition of fragmentation effects that erode genetic variation. If effective population size is used to set recovery goals for endangered species, then habitat fragmentation effects may be sufficiently strong to prevent evaluation of recovery based on the ratio of census:effective population size alone.

Relationship between gait initiation and disability in individuals affected by multiple sclerosis.

PubMed

Galli, Manuela; Coghe, Giancarlo; Sanna, Paola; Cocco, Eleonora; Marrosu, Maria Giovanna; Pau, Massimiliano

2015-11-01

This study analyzes how multiple sclerosis (MS) does affect one of the most common voluntary activities in life: the gait initiation (GI). The main aim of the work is to characterize the execution of this task by measuring and comparing relevant parameters based on center of pressure (COP) patterns and to study the relationship between these and the level of expanded disability status scale (EDSS). To this aim, 95 MS subjects with an average EDSS score of 2.4 and 35 healthy subjects were tested using a force platform during the transition from standing posture to gait. COP time-series were acquired and processed to extract a number of parameters related to the trajectory followed by the COP. The statistical analysis revealed that only a few measurements were statistically different between the two groups and only these were subsequently correlated with EDSS score. The correlation analysis underlined that a progressive alteration of the task execution can be directly related with the increase of EDSS score. These finding suggest that most of the impairment found in people with MS comes from the first part of the COP pattern, the anticipatory postural adjustments (APAs). The central nervous system performs APAs before every voluntary movement to minimize balance perturbation due to the movement itself. Gait Initiation's APAs consist in some ankle muscles contractions that induce a backward COP shift to the swing limb. The analysis here performed highlighted that MS affected patients have a reduced posterior COP shift that reveals that the anticipatory mechanism is impaired. Copyright © 2015 Elsevier B.V. All rights reserved.

The moderating role of overcommitment in the relationship between psychological contract breach and employee mental health.

PubMed

Reimann, Mareike

2016-09-30

This study investigated whether the association between perceived psychological contract breach (PCB) and employee mental health is moderated by the cognitive-motivational pattern of overcommitment (OC). Linking the psychological contract approach to the effort-reward imbalance model, this study examines PCB as an imbalance in employment relationships that acts as a psychosocial stressor in the work environment and is associated with stress reactions that in turn negatively affect mental health. The analyses were based on a sample of 3,667 employees who participated in a longitudinal linked employer-employee survey representative of large organizations (with at least 500 employees who are subject so social security contributions) in Germany. Fixed-effects regression models, including PCB and OC, were estimated for employee mental health, and interaction effects between PCB and OC were assessed. The multivariate fixed-effects regression analyses showed a significant negative association between PCB and employee mental health. The results also confirmed that OC does indeed significantly increase the negative effect of PCB on mental health and that OC itself has a significant and negative effect on mental health. The results suggest that employees characterized by the cognitive-motivational pattern of OC are at an increased risk of developing poor mental health if they experience PCB compared with employees who are not overly committed to their work. The results of this study support the assumption that psychosocial work stressors play an important role in employee mental health.

The moderating role of overcommitment in the relationship between psychological contract breach and employee mental health

PubMed Central

Reimann, Mareike

2016-01-01

Objectives: This study investigated whether the association between perceived psychological contract breach (PCB) and employee mental health is moderated by the cognitive-motivational pattern of overcommitment (OC). Linking the psychological contract approach to the effort-reward imbalance model, this study examines PCB as an imbalance in employment relationships that acts as a psychosocial stressor in the work environment and is associated with stress reactions that in turn negatively affect mental health. Methods: The analyses were based on a sample of 3,667 employees who participated in a longitudinal linked employer-employee survey representative of large organizations (with at least 500 employees who are subject so social security contributions) in Germany. Fixed-effects regression models, including PCB and OC, were estimated for employee mental health, and interaction effects between PCB and OC were assessed. Results: The multivariate fixed-effects regression analyses showed a significant negative association between PCB and employee mental health. The results also confirmed that OC does indeed significantly increase the negative effect of PCB on mental health and that OC itself has a significant and negative effect on mental health. Conclusions: The results suggest that employees characterized by the cognitive-motivational pattern of OC are at an increased risk of developing poor mental health if they experience PCB compared with employees who are not overly committed to their work. The results of this study support the assumption that psychosocial work stressors play an important role in employee mental health. PMID:27488041

Forecasts of Agricultural Drought in Sri Lanka

NASA Astrophysics Data System (ADS)

Gilligan, J. M.; Gunda, T.; Hornberger, G. M.

2015-12-01

As the most frequent natural disaster in Sri Lanka, drought greatly affects crop production and livelihoods. Over half of all agricultural crop damage in Sri Lanka is currently due to drought; the frequency and severity of drought in the country is only expected to increase with the changing climate. Previous work indicates that the Palmer Drought Severity Index (PDSI) and Standardized Precipitation Index (SPI) are capable of capturing agricultural drought patterns (between 1881-2010) in the island nation. In this work, PDSI and SPI from 13 long-term meteorological stations will be projected into the future using a combination of artificial neural network and autoregressive integrated moving average models. The impacts of large-scale atmospheric circulation patterns (such as the Niño 3.4 index, a measure of sea surface temperature) and lead times on projection accuracy will also be explored. Model projections will be compared to weather data since 2010 to determine if the 2014 drought could have been forecasted using these methods. Since agricultural systems are strongly influenced by both natural and human systems, it is important to frame these physical findings within a social context. This work is part of an interdisciplinary project that assesses the perceptions of and adaptations to drought by rice farmers in Sri Lanka; disciplines represented in the group include hydrology, social psychology, ethnography, policy, and behavioral economics. Insights from the diverse research perspectives within the group will be drawn upon to highlight the social implications of the physical results.

Spatiotemporal ecohydrological patterns and processes in temperate uplands: linking field observations and model results

NASA Astrophysics Data System (ADS)

Dodd, N. H.; Baird, A. J.; Wainwright, J.; Dunn, S. M.

2011-12-01

There are obvious surface expressions - in terms of vegetation patterning - of ecohydrological feedbacks on dryland and peatland hillslopes. Much less is known about subsurface ecohydrological patterns, and whether or not they 'map onto' surface patterns. Likewise, few attempts have been made to investigate how such ecohydrological patterns affect whole-hillslope hydrological behaviour or how widespread they are in non-dryland and non-peatland hillslopes. In this study we investigate surface and near- surface patterning in temperate hillslopes, which to date have been the focus of much hydrological work but little ecohydrological work. In particular, we consider the extent to which the direct and the indirect effects of past and present plant assemblages on local and whole-hillslope soil moisture conditions may contribute to patterning. We have conducted a field study of two temperate upland hillslopes in Northern Scotland, UK, on one of which human intervention plays a major part in shaping the landscape. Repeat measurements have been made of near- surface soil-moisture content, taken at lag distances of 0.25 m to 20 m, under different antecedent hydrological conditions together with characterisation of plant assemblages at the same points through both ground-based vegetation surveys of 1 m × 1 m plots and kite aerial photography (KAP) of > 20 m2 plots. Results from this have indicated that changes in ecohydrological patterns can occur over small spatial scales (< 1 m2) and short time scales (< 1 day). Comparison of values of near-surface soil moisture content with topographic wetness indices, calculated using 1 -m resolution topographic data collected in the field, has highlighted that topography does not explain all of the spatial variation in soil moisture content at this scale. KAP images allowed detection of vegetation patterns not obvious from the ground. Comparison of KAP images and historic aerial photographs has highlighted the persistence of vegetation patterns over time at both sites, and that the current structure of the landscape is clearly related to current and past vegetation management practices. Evidence of sustained patterning under relatively steady environmental conditions has prompted us to consider how internal system dynamics such as competition and facilitation between different plant assemblages, and persistence of ecological memory at a range of timescales may lead to a range of ecohydrological behaviours at the scale of whole hillslopes. To help conceptualize ways in which patterning may arise, we have built a two-dimensional cellular automata-type model in which local interactions between biotic and abiotic components have the potential to lead to emergence of larger-scale patterns within the model landscape. Results from the field study have been used to gauge how well temperate hillslope ecohydrological dynamics are represented in our model, and to check that local neighbourhood patterns in the model outputs resemble real-world patterning. Key words: temperate upland ecohydrology, plant assemblage dynamics, ecological memory, kite aerial photography, cellular automata.

Tracking affect and academic success across university: Happy students benefit from bouts of negative mood.

PubMed

Barker, Erin T; Howard, Andrea L; Galambos, Nancy L; Wrosch, Carsten

2016-12-01

We examined how positive and negative affect covary within individuals over time and how patterns of association between affective traits and states relate to academic success across 4 years of university. Participants were 187 full-time first-year students at a large Canadian university who completed questionnaires about recent affective experiences in 6 waves across 4 years. Grade point average for each year of study was provided by the registrar's office. Our analysis identified an adaptive pattern characterized by the maintenance of high positive affect ("chronic happiness") and the cooccurrence of time-limited bouts of negative affect. Our results are consistent with findings showing productive consequences of experiencing positive and negative affect in tandem and the development of emotion regulation capacity across the transition to adulthood. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Short-term cessation of sex work and injection drug use: evidence from a recurrent event survival analysis.

PubMed

Gaines, Tommi L; Urada, Lianne A; Martinez, Gustavo; Goldenberg, Shira M; Rangel, Gudelia; Reed, Elizabeth; Patterson, Thomas L; Strathdee, Steffanie A

2015-06-01

This study quantitatively examined the prevalence and correlates of short-term sex work cessation among female sex workers who inject drugs (FSW-IDUs) and determined whether injection drug use was independently associated with cessation. We used data from FSW-IDUs (n=467) enrolled into an intervention designed to increase condom use and decrease sharing of injection equipment but was not designed to promote sex work cessation. We applied a survival analysis that accounted for quit-re-entry patterns of sex work over 1-year stratified by city, Tijuana and Ciudad Juarez, Mexico. Overall, 55% of participants stopped sex work at least once during follow-up. Controlling for other characteristics and intervention assignment, injection drug use was inversely associated with short-term sex work cessation in both cities. In Ciudad Juarez, women receiving drug treatment during follow-up had a 2-fold increase in the hazard of stopping sex work. In both cities, income from sources other than sex work, police interactions and healthcare access were independently and significantly associated with shorter-term cessation. Short-term sex work cessation was significantly affected by injection drug use. Expanded drug treatment and counseling coupled with supportive services such as relapse prevention, job training, and provision of alternate employment opportunities may promote longer-term cessation among women motivated to leave the sex industry. Copyright © 2015 Elsevier Ltd. All rights reserved.

Short-Term Cessation of Sex Work and Injection Drug Use: Evidence from a Recurrent Event Survival Analysis

PubMed Central

Gaines, Tommi L.; Urada, Lianne; Martinez, Gustavo; Goldenberg, Shira M.; Rangel, Gudelia; Reed, Elizabeth; Patterson, Thomas L.; Strathdee, Steffanie A.

2015-01-01

Objective This study quantitatively examined the prevalence and correlates of short-term sex work cessation among female sex workers who inject drugs (FSW-IDUs) and determined whether injection drug use was independently associated with cessation. Methods We used data from FSW-IDUs (n=467) enrolled into an intervention designed to increase condom use and decrease sharing of injection equipment but was not designed to promote sex work cessation. We applied a survival analysis that accounted for quit-re-entry patterns of sex work over 1-year stratified by city, Tijuana and Ciudad Juarez, Mexico. Results Overall, 55% of participants stopped sex work at least once during follow-up. Controlling for other characteristics and intervention assignment, injection drug use was inversely associated with short-term sex work cessation in both cities. In Ciudad Juarez, women receiving drug treatment during follow-up had a 2-fold increase in the hazard of stopping sex work. In both cities, income from sources other than sex work, police interactions and healthcare access were independently and significantly associated with shorter-term cessation. Conclusions Short-term sex work cessation was significantly affected by injection drug use. Expanded drug treatment and counseling coupled with supportive services such as relapse prevention, job training, and provision of alternate employment opportunities may promote longer-term cessation among women motivated to leave the sex industry. PMID:25644589

Planting pattern and weed control method influence on yield production of corn (Zea mays L.)

NASA Astrophysics Data System (ADS)

Purba, E.; Nasution, D. P.

2018-02-01

Field experiment was carried out to evaluate the influence of planting patterns and weed control methods on the growth and yield of corn. The effect of the planting pattern and weed control method was studied in a split plot design. The main plots were that of planting pattern single row (25cm x 60cm), double row (25cm x 25cm x 60cm) and triangle row ( 25cm x 25cm x 25cm). Subplot was that of weed control method consisted five methods namely weed free throughout the growing season, hand weeding, sprayed with glyphosate, sprayed with paraquat, and no weeding.. Result showed that both planting pattern and weed control method did not affect the growth of corn. However, planting pattern and weed control method significantly affected yield production. Yield resulted from double row and triangle planting pattern was 14% and 41% higher, consecutively, than that of single row pattern. The triangle planting pattern combined with any weed control method produced the highest yield production of corn.

Simulation of range imaging-based estimation of respiratory lung motion. Influence of noise, signal dimensionality and sampling patterns.

PubMed

Wilms, M; Werner, R; Blendowski, M; Ortmüller, J; Handels, H

2014-01-01

A major problem associated with the irradiation of thoracic and abdominal tumors is respiratory motion. In clinical practice, motion compensation approaches are frequently steered by low-dimensional breathing signals (e.g., spirometry) and patient-specific correspondence models, which are used to estimate the sought internal motion given a signal measurement. Recently, the use of multidimensional signals derived from range images of the moving skin surface has been proposed to better account for complex motion patterns. In this work, a simulation study is carried out to investigate the motion estimation accuracy of such multidimensional signals and the influence of noise, the signal dimensionality, and different sampling patterns (points, lines, regions). A diffeomorphic correspondence modeling framework is employed to relate multidimensional breathing signals derived from simulated range images to internal motion patterns represented by diffeomorphic non-linear transformations. Furthermore, an automatic approach for the selection of optimal signal combinations/patterns within this framework is presented. This simulation study focuses on lung motion estimation and is based on 28 4D CT data sets. The results show that the use of multidimensional signals instead of one-dimensional signals significantly improves the motion estimation accuracy, which is, however, highly affected by noise. Only small differences exist between different multidimensional sampling patterns (lines and regions). Automatically determined optimal combinations of points and lines do not lead to accuracy improvements compared to results obtained by using all points or lines. Our results show the potential of multidimensional breathing signals derived from range images for the model-based estimation of respiratory motion in radiation therapy.

Spatial controls of occurrence and spread of wildfires in the Missouri Ozark Highlands.

PubMed

Yang, Jian; He, Hong S; Shifley, Stephen R

2008-07-01

Understanding spatial controls on wildfires is important when designing adaptive fire management plans and optimizing fuel treatment locations on a forest landscape. Previous research about this topic focused primarily on spatial controls for fire origin locations alone. Fire spread and behavior were largely overlooked. This paper contrasts the relative importance of biotic, abiotic, and anthropogenic constraints on the spatial pattern of fire occurrence with that on burn probability (i.e., the probability that fire will spread to a particular location). Spatial point pattern analysis and landscape succession fire model (LANDIS) were used to create maps to show the contrast. We quantified spatial controls on both fire occurrence and fire spread in the Midwest Ozark Highlands region, USA. This area exhibits a typical anthropogenic surface fire regime. We found that (1) human accessibility and land ownership were primary limiting factors in shaping clustered fire origin locations; (2) vegetation and topography had a negligible influence on fire occurrence in this anthropogenic regime; (3) burn probability was higher in grassland and open woodland than in closed-canopy forest, even though fire occurrence density was less in these vegetation types; and (4) biotic and abiotic factors were secondary descriptive ingredients for determining the spatial patterns of burn probability. This study demonstrates how fire occurrence and spread interact with landscape patterns to affect the spatial distribution of wildfire risk. The application of spatial point pattern data analysis would also be valuable to researchers working on landscape forest fire models to integrate historical ignition location patterns in fire simulation.

Event-Related Beta EEG Changes During Active, Passive Movement and Functional Electrical Stimulation of the Lower Limb.

PubMed

Qiu, Shuang; Yi, Weibo; Xu, Jiapeng; Qi, Hongzhi; Du, Jingang; Wang, Chunfang; He, Feng; Ming, Dong

2016-02-01

A number of electroencephalographic (EEG) studies have reported on event-related desynchronization/synchronization (ERD/ERS) during active movements, passive movements, and the movements induced by functional electrical stimulation (FES). However, the quantitative differences in ERD values and affected frequency bands associated with the lower limb have not been discussed. The goal of this paper was to quantitatively compare the ERD patterns during active movement, passive movement and FES-induced movement of the lower limb. 64-channel EEG signals were recorded to investigate the brain oscillatory patterns during active movement, passive movement and FES-induced movement of the lower limb in twelve healthy subjects. And passive movement and FES-induced movement were also performed in a hemiplegic stroke patient. For healthy subjects, FES-induced movement presented significantly higher characteristic frequency of central beta ERD while there was no significant difference in ERD values compared with active or passive movement. Meanwhile, beta ERD values of FES-induced movement were significantly correlated with those of active movement, and spatial distribution of beta ERD pattern for FES-induced movement was more correlated with that for active movement. In addition, the stroke patient presented central ERD patterns during FES-induced movement, while no ERD with similar frequencies could be found during passive movement. This work implies that the EEG oscillatory pattern under FES-induced movement tends more towards active movement instead of passive movement. The quantification of ERD patterns could be expected as a potential technique to evaluate the brain response during FES-induced movement.

Neurocognitive Allied Phenotypes for Schizophrenia and Bipolar Disorder

PubMed Central

Hill, S. Kristian; Harris, Margret S. H.; Herbener, Ellen S.; Pavuluri, Mani; Sweeney, John A.

2008-01-01

Psychiatric disorders are genetically complex and represent the end product of multiple biological and social factors. Links between genes and disorder-related abnormalities can be effectively captured via assessment of phenotypes that are both associated with genetic effects and potentially contributory to behavioral abnormalities. Identifying intermediate or allied phenotypes as a strategy for clarifying genetic contributions to disorders has been successful in other areas of medicine and is a promising strategy for identifying susceptibility genes in complex psychiatric disorders. There is growing evidence that schizophrenia and bipolar disorder, rather than being wholly distinct disorders, share genetic risk at several loci. Further, there is growing evidence of similarity in the pattern of cognitive and neurobiological deficits in these groups, which may be the result of the effects of these common genetic factors. This review was undertaken to identify patterns of performance on neurocognitive and affective tasks across probands with schizophrenia and bipolar disorder as well as unaffected family members, which warrant further investigation as potential intermediate trait markers. Available evidence indicates that measures of attention regulation, working memory, episodic memory, and emotion processing offer potential for identifying shared and illness-specific allied neurocognitive phenotypes for schizophrenia and bipolar disorder. However, very few studies have evaluated neurocognitive dimensions in bipolar probands or their unaffected relatives, and much work in this area is needed. PMID:18448479

Gender differences in physical activity patterns among older adults who fall.

PubMed

Stahl, Sarah T; Albert, Steven M

2015-02-01

This study describes gender differences in the level and pattern of physical activity in groups of older adults who were frequent fallers, intermittent fallers, or non-fallers. Interviews were conducted with adults aged 50 years and older (N=1834) at senior centers across Pennsylvania from 2010 to 2011. Self-reported falls and validated measures of physical activity were collected at baseline and at 6- and 12-month follow-up assessments. Complete follow-up data were available for 1487 participants. Men who fell frequently decreased in recreational/leisure activity and household/yard work compared to the intermittent fallers and non-fallers. This association remained even when controlling for baseline health status. All women-regardless of fall group-engaged in similar levels of recreational/leisure activity and household/yard work over time. For both men and women, frequent fallers also showed a greater decrease in walking activities compared to intermittent fallers and non-fallers. Frequent falling among older adults is associated with declines in common leisure, household, and walking activities. The effect of falling frequency on physical activity appears to affect men and women differently, generating the hypothesis that interventions to promote physical activity among fallers need to be gender specific. Copyright © 2014 Elsevier Inc. All rights reserved.

Theoretical analysis of non-linear Joule heating effects over an electro-thermal patterned flow

NASA Astrophysics Data System (ADS)

Sanchez, Salvador; Ascanio, Gabriel; Mendez, Federico; Bautista, Oscar

2017-11-01

In this work, non-linear Joule heating effects for electro-thermal patterned flows driven inside of a slit microchannel are analyzed. Here, the movement of fluids is controlled by placing electro-thermal forces, which are generated through an imposed longitudinal electric field, E0, and the wall electric potential produced by electrodes inserted along the surface of the microchannel wall, ζ. For this analysis, viscosity and electrical conductivity of fluids are included as known functions, which depend on the temperature; therefore, in order to determine the flow, temperature and electric potential fields together with its simultaneous interactions, the equations of continuity, momentum, energy, charges distribution and electrical current have to be solved in a coupled manner. The main results obtained in the study reveal that with the presence of thermal gradients along of the microchannel, local electro-thermal forces, Fχ, are affected in a sensible manner, and consequently, the flow field is modified substantially, causing the interruption or intensification of recirculations along of the microchannel. This work was supported by the Fondo SEP-CONACYT through research Grants No. 220900 and 20171181 from SIP-IPN. F. Mendez acknowledges support from PAPIIT-UNAM under Contract Number IN112215. S. Sanchez thanks to DGAPA-UNAM for the postdoctoral fellowship.

The Risk Implications of Globalisation: An Exploratory Analysis of 105 Major Industrial Incidents (1971–2010)

PubMed Central

Beck, Matthias

2016-01-01

This paper revisits work on the socio-political amplification of risk, which predicts that those living in developing countries are exposed to greater risk than residents of developed nations. This prediction contrasts with the neoliberal expectation that market driven improvements in working conditions within industrialising/developing nations will lead to global convergence of hazard exposure levels. It also contradicts the assumption of risk society theorists that there will be an ubiquitous increase in risk exposure across the globe, which will primarily affect technically more advanced countries. Reviewing qualitative evidence on the impact of structural adjustment reforms in industrialising countries, the export of waste and hazardous waste recycling to these countries and new patterns of domestic industrialisation, the paper suggests that workers in industrialising countries continue to face far greater levels of hazard exposure than those of developed countries. This view is confirmed when a data set including 105 major multi-fatality industrial disasters from 1971 to 2000 is examined. The paper concludes that there is empirical support for the predictions of socio-political amplification of risk theory, which finds clear expression in the data in a consistent pattern of significantly greater fatality rates per industrial incident in industrialising/developing countries. PMID:26978378

An fMRI study of working memory in first-degree unaffected relatives of schizophrenia patients.

PubMed

Meda, Shashwath A; Bhattarai, Manish; Morris, Nicholas A; Astur, Robert S; Calhoun, Vince D; Mathalon, Daniel H; Kiehl, Kent A; Pearlson, Godfrey D

2008-09-01

Identifying intermediate phenotypes of genetically complex psychiatric illnesses such as schizophrenia is important. First-degree relatives of persons with schizophrenia have increased genetic risk for the disorder and tend to show deficits on working memory (WM) tasks. An open question is the relationship between such behavioral endophenotypes and the corresponding brain activation patterns revealed during functional imaging. We measured task performance during a Sternberg WM task and used functional magnetic resonance imaging (fMRI) to assess whether 23 non-affected first-degree relatives showed altered performance and functional activation compared to 43 matched healthy controls. We predicted that a significant proportion of unaffected first-degree relatives would show either aberrant task performance and/or abnormal related fMRI blood oxygen level dependent (BOLD) patterns. While task performance in the relatives was not different than that of controls they were significantly slower in responding to probes., Schizophrenia relatives displayed reduced activation, most markedly in bilateral dorsolateral/ventrolateral (DLPFC/VLPFC) prefrontal and posterior parietal cortex when encoding stimuli and in bilateral DLPFC and parietal areas during response selection. Additionally, fMRI differences in both conditions were modulated by load, with a parametric increase in between-group differences with load in several key regions during encoding and an opposite effect during response selection.

Multitasking: Effects of processing multiple auditory feature patterns

PubMed Central

Miller, Tova; Chen, Sufen; Lee, Wei Wei; Sussman, Elyse S.

2016-01-01

ERPs and behavioral responses were measured to assess how task-irrelevant sounds interact with task processing demands and affect the ability to monitor and track multiple sound events. Participants listened to four-tone sequential frequency patterns, and responded to frequency pattern deviants (reversals of the pattern). Irrelevant tone feature patterns (duration and intensity) and respective pattern deviants were presented together with frequency patterns and frequency pattern deviants in separate conditions. Responses to task-relevant and task-irrelevant feature pattern deviants were used to test processing demands for irrelevant sound input. Behavioral performance was significantly better when there were no distracting feature patterns. Errors primarily occurred in response to the to-be-ignored feature pattern deviants. Task-irrelevant elicitation of ERP components was consistent with the error analysis, indicating a level of processing for the irrelevant features. Task-relevant elicitation of ERP components was consistent with behavioral performance, demonstrating a “cost” of performance when there were two feature patterns presented simultaneously. These results provide evidence that the brain tracked the irrelevant duration and intensity feature patterns, affecting behavioral performance. Overall, our results demonstrate that irrelevant informational streams are processed at a cost, which may be considered a type of multitasking that is an ongoing, automatic processing of taskirrelevant sensory events. PMID:25939456

Health professionals' migration in emerging market economies: patterns, causes and possible solutions.

PubMed

Nair, Manisha; Webster, Premila

2013-03-01

About a third of the countries affected by shortage of human resources for health are the emerging market economies (EMEs). The greatest shortage in absolute terms was found to be in India and Indonesia leading to health system crisis. This review identifies the patterns of migration of health workers, causes and possible solutions in these EMEs. A qualitative synthesis approach based on the 'critical review' and 'realist review' approaches to the literature review was used. The patterns of migration of health professionals' in the EMEs have led to two types of discrepancies between health needs and healthcare workers: (i) within country (rural-urban, public-private or government healthcare sector-private sector) and (ii) across countries (south to north). Factors that influence migration include lack of employment opportunities, appropriate work environment and wages in EMEs, growing demand in high-income countries due to demographic transition, favourable country policies for financial remittances by migrant workers and medical education system of EMEs. A range of successful national and international initiatives to address health workforce migration were identified. Measures to control migration should be country specific and designed in accordance with the push and pull factors existing in the EMEs.

Effect of di-amphetamine injected into N. Accumbens on ethanol self-administration in the rat

DOE Office of Scientific and Technical Information (OSTI.GOV)

Samson, H.H.; Tolliver, G.A.; Haraguchi, M.

1991-03-11

Adult, male Long-Evans rats were initiated to lever press with 10% (v/v) ethanol reinforcement using the sucrose-fading technique. Following initiation and the development of stable ethanol self-administration behavior, bilateral cannula guides directed at the N.Accumbens were surgically implanted. Following recovery, the animals received microinjections once a week of either saline, 4, 10 or 20 ug/brain of dl-amphetamine sulfate dissolved in saline. Injections were 10 minutes prior to the daily 30min ethanol self-administration session.; At all doses tested, amphetamine had no significant effect upon the number of responses or ethanol. Reinforcements received during the session. However, a clear alteration in themore » pattern of responding was found at the 10 and 20 ug dose, with some animals showing effects at 4 ug. This alteration in response pattern with no effect upon total responding is different from prior work using systemic amphetamine injections, where both pattern and number of responses were affected. The data suggest that some but not all of the systemic effects could be related to amphetamine's actions on the N. Accumbens.« less

Effects of strain rate and surface cracks on the mechanical behaviour of Balmoral Red granite.

PubMed

Mardoukhi, Ahmad; Mardoukhi, Yousof; Hokka, Mikko; Kuokkala, Veli-Tapani

2017-01-28

This work presents a systematic study on the effects of strain rate and surface cracks on the mechanical properties and behaviour of Balmoral Red granite. The tensile behaviour of the rock was studied at low and high strain rates using Brazilian disc samples. Heat shocks were used to produce samples with different amounts of surface cracks. The surface crack patterns were analysed using optical microscopy, and the complexity of the patterns was quantified by calculating the fractal dimensions of the patterns. The strength of the rock clearly drops as a function of increasing fractal dimensions in the studied strain rate range. However, the dynamic strength of the rock drops significantly faster than the quasi-static strength, and, because of this, also the strain rate sensitivity of the rock decreases with increasing fractal dimensions. This can be explained by the fracture behaviour and fragmentation during the dynamic loading, which is more strongly affected by the heat shock than the fragmentation at low strain rates.This article is part of the themed issue 'Experimental testing and modelling of brittle materials at high strain rates'. © 2016 The Author(s).

Effects of strain rate and surface cracks on the mechanical behaviour of Balmoral Red granite

PubMed Central

Kuokkala, Veli-Tapani

2017-01-01

This work presents a systematic study on the effects of strain rate and surface cracks on the mechanical properties and behaviour of Balmoral Red granite. The tensile behaviour of the rock was studied at low and high strain rates using Brazilian disc samples. Heat shocks were used to produce samples with different amounts of surface cracks. The surface crack patterns were analysed using optical microscopy, and the complexity of the patterns was quantified by calculating the fractal dimensions of the patterns. The strength of the rock clearly drops as a function of increasing fractal dimensions in the studied strain rate range. However, the dynamic strength of the rock drops significantly faster than the quasi-static strength, and, because of this, also the strain rate sensitivity of the rock decreases with increasing fractal dimensions. This can be explained by the fracture behaviour and fragmentation during the dynamic loading, which is more strongly affected by the heat shock than the fragmentation at low strain rates. This article is part of the themed issue ‘Experimental testing and modelling of brittle materials at high strain rates’. PMID:27956513

Patient-Clinician Ethnic Concordance and Communication in Mental Health Intake Visits

PubMed Central

Alegría, Margarita; Roter, Debra L.; Valentine, Anne; Chen, Chih-nan; Li, Xinliang; Lin, Julia; Rosen, Daniel; Lapatin, Sheri; Normand, Sharon-Lise; Larson, Susan; Shrout, Patrick E.

2013-01-01

Objective This study examines how communication patterns vary across racial and ethnic patient-clinician dyads in mental health intake sessions and its relation to continuance in treatment, defined as attending the next scheduled appointment. Methods Observational study of communication patterns among ethnically/racially concordant and discordant patient-clinician dyads. Primary analysis included 93 patients with 38 clinicians in race/ethnic concordant and discordant dyads. Communication was coded using the Roter Interaction Analysis System (RIAS) and the Working Alliance Inventory Observer (WAI-O) bond scale; continuance in care was derived from chart reviews. Results Latino concordant dyad patients were more verbally dominant (p<.05), engaged in more patient-centered communication (p<.05) and scored higher on the (WAI-O) bond scale (all p<.05) than other groups. Latino patients had higher continuance rates than other patients in models that adjusted for non-communication variables. When communication, global affect, and therapeutic process variables were adjusted for, differences were reversed and white dyad patients had higher continuance in care rates than other dyad patients. Conclusion Communication patterns seem to explain the role of ethnic concordance for continuance in care. Practice Implications Improve intercultural communication in cross cultural encounters appears significant for retaining minorities in care. PMID:23896127

Effect of Charge Patterning on the Phase Behavior of Polymer Coacervates for Charge Driven Self Assembly

NASA Astrophysics Data System (ADS)

Radhakrishna, Mithun; Sing, Charles E.

Oppositely charged polymers can undergo associative liquid-liquid phase separation when mixed under suitable conditions of ionic strength, temperature and pH to form what are known as `polymeric complex coacervates'. Polymer coacervates find use in diverse array of applications like microencapsulation, drug delivery, membrane filtration and underwater adhesives. The similarity between complex coacervate environments and those in biological systems has also found relevance in areas of bio-mimicry. Our previous works have demonstrated how local charge correlations and molecular connectivity can drastically affect the phase behavior of coacervates. The precise location of charges along the chain therefore dramatically influences the local charge correlations, which consequently influences the phase behavior of coacervates. We investigate the effect of charge patterning along the polymer chain on the phase behavior of coacervates in the framework of the Restricted Primitive Model using Gibbs Ensemble Monte Carlo simulations. Our results show that charge patterning dramatically changes the phase behavior of polymer coacervates, which contrasts with the predictions of the classical Voorn-Overbeek theory. This provides the basis for designing new materials through charge driven self assembly by controlling the positioning of the charged monomers along the chain.

Using an Android application to assess registration strategies in open hepatic procedures: a planning and simulation tool

NASA Astrophysics Data System (ADS)

Doss, Derek J.; Heiselman, Jon S.; Collins, Jarrod A.; Weis, Jared A.; Clements, Logan W.; Geevarghese, Sunil K.; Miga, Michael I.

2017-03-01

Sparse surface digitization with an optically tracked stylus for use in an organ surface-based image-to-physical registration is an established approach for image-guided open liver surgery procedures. However, variability in sparse data collections during open hepatic procedures can produce disparity in registration alignments. In part, this variability arises from inconsistencies with the patterns and fidelity of collected intraoperative data. The liver lacks distinct landmarks and experiences considerable soft tissue deformation. Furthermore, data coverage of the organ is often incomplete or unevenly distributed. While more robust feature-based registration methodologies have been developed for image-guided liver surgery, it is still unclear how variation in sparse intraoperative data affects registration. In this work, we have developed an application to allow surgeons to study the performance of surface digitization patterns on registration. Given the intrinsic nature of soft-tissue, we incorporate realistic organ deformation when assessing fidelity of a rigid registration methodology. We report the construction of our application and preliminary registration results using four participants. Our preliminary results indicate that registration quality improves as users acquire more experience selecting patterns of sparse intraoperative surface data.

Coherent Pattern Prediction in Swarms of Delay-Coupled Agents

NASA Astrophysics Data System (ADS)

Mier-Y-Teran-Romero, Luis; Forgoston, Eric; Scwartz, Ira

2013-03-01

We consider a general swarm model of self-propelling particles interacting through a pairwise potential in the presence of a fixed communication time delay. Previous work has shown that swarms with communication time delays and noise may display pattern transitions that depend on the size of the coupling amplitude. We extend these results by completely unfolding the bifurcation structure of the mean field approximation. Our analysis reveals a direct correspondence between the different dynamical behaviors found in different regions of the coupling-time delay plane with the different classes of simulated coherent swarm patterns. We derive the spatio-temporal scales of the swarm structures, and also demonstrate how the complicated interplay of coupling strength, time delay, noise intensity, and choice of initial conditions can affect the swarm. In addition, when adding noise to the system, we find that for sufficiently large values of the coupling strength and/or the time delay, there is a noise intensity threshold that forces a transition of the swarm from a misaligned state into an aligned state. We show that this alignment transition exhibits hysteresis when the noise intensity is taken to be time dependent. Office of Naval Research, NIH (LMR and IBS) and NRL (EF)

Global diversity patterns in sandy beach macrofauna: a biogeographic analysis.

PubMed

Barboza, Francisco Rafael; Defeo, Omar

2015-09-28

Unlike the advances generated on land, the knowledge of global diversity patterns in marine ecosystems is limited to a small number of studies. For sandy beaches, which dominate the world's ocean shores, previous meta-analyses highlighted the role of beach morphodynamics in explaining species richness patterns. Oceanographic variables and historical processes have not been considered, even though they could be main predictors of community structure. Our work, based on 256 sandy beaches around the world, analysed species richness considering for the first time temperature, salinity and primary productivity. Biogeographic units (realms, provinces and ecoregions) were used to incorporate historical factors in modelling processes. Ecoregions, which implicitly include isolation and coastal complexity among other historical geographic factors, best represented trends in species richness worldwide. Temperature was a main predictor of species richness, which increased from temperate to tropical sandy beaches. Species richness increased with tide range and towards wide beaches with gentle slopes and fine grains, which is consistent with the hypothesis that habitat availability has an important role in structuring sandy beach communities. The role of temperature and habitat availability suggests that ocean warming and sea level rise could affect the distribution of obligate species living in these narrow ecosystems.

Global diversity patterns in sandy beach macrofauna: a biogeographic analysis

PubMed Central

Rafael Barboza, Francisco; Defeo, Omar

2015-01-01

Unlike the advances generated on land, the knowledge of global diversity patterns in marine ecosystems is limited to a small number of studies. For sandy beaches, which dominate the world’s ocean shores, previous meta-analyses highlighted the role of beach morphodynamics in explaining species richness patterns. Oceanographic variables and historical processes have not been considered, even though they could be main predictors of community structure. Our work, based on 256 sandy beaches around the world, analysed species richness considering for the first time temperature, salinity and primary productivity. Biogeographic units (realms, provinces and ecoregions) were used to incorporate historical factors in modelling processes. Ecoregions, which implicitly include isolation and coastal complexity among other historical geographic factors, best represented trends in species richness worldwide. Temperature was a main predictor of species richness, which increased from temperate to tropical sandy beaches. Species richness increased with tide range and towards wide beaches with gentle slopes and fine grains, which is consistent with the hypothesis that habitat availability has an important role in structuring sandy beach communities. The role of temperature and habitat availability suggests that ocean warming and sea level rise could affect the distribution of obligate species living in these narrow ecosystems. PMID:26411697

Laser Processing of Multilayered Thermal Spray Coatings: Optimal Processing Parameters

NASA Astrophysics Data System (ADS)

Tewolde, Mahder; Zhang, Tao; Lee, Hwasoo; Sampath, Sanjay; Hwang, David; Longtin, Jon

2017-12-01

Laser processing offers an innovative approach for the fabrication and transformation of a wide range of materials. As a rapid, non-contact, and precision material removal technology, lasers are natural tools to process thermal spray coatings. Recently, a thermoelectric generator (TEG) was fabricated using thermal spray and laser processing. The TEG device represents a multilayer, multimaterial functional thermal spray structure, with laser processing serving an essential role in its fabrication. Several unique challenges are presented when processing such multilayer coatings, and the focus of this work is on the selection of laser processing parameters for optimal feature quality and device performance. A parametric study is carried out using three short-pulse lasers, where laser power, repetition rate and processing speed are varied to determine the laser parameters that result in high-quality features. The resulting laser patterns are characterized using optical and scanning electron microscopy, energy-dispersive x-ray spectroscopy, and electrical isolation tests between patterned regions. The underlying laser interaction and material removal mechanisms that affect the feature quality are discussed. Feature quality was found to improve both by using a multiscanning approach and an optional assist gas of air or nitrogen. Electrically isolated regions were also patterned in a cylindrical test specimen.

Advance cueing produces enhanced action-boundary patterns of spike activity in the sensorimotor striatum

PubMed Central

Barnes, Terra D.; Mao, Jian-Bin; Hu, Dan; Kubota, Yasuo; Dreyer, Anna A.; Stamoulis, Catherine; Brown, Emery N.

2011-01-01

One of the most characteristic features of habitual behaviors is that they can be evoked by a single cue. In the experiments reported here, we tested for the effects of such advance cueing on the firing patterns of striatal neurons in the sensorimotor striatum. Rats ran in a T-maze with instruction cues about the location of reward given at the start of the runs. This advance cueing about reward produced a highly augmented task-bracketing pattern of activity at the beginning and end of procedural task performance relative to the patterns found previously with midtask cueing. Remarkably, the largest increase in activity early during the T-maze runs was not associated with the instruction cues themselves, the earliest predictors of reward; instead, the highest peak of early activity was associated with the beginning of the motor period of the task. We suggest that the advance cueing, reducing midrun demands for decision making but adding a working-memory load, facilitated chunking of the maze runs as executable scripts anchored to sensorimotor aspects of the task and unencumbered by midtask decision-making demands. Our findings suggest that the acquisition of stronger task-bracketing patterns of striatal activity in the sensorimotor striatum could reflect this enhancement of behavioral chunking. Deficits in such representations of learned sequential behaviors could contribute to motor and cognitive problems in a range of neurological disorders affecting the basal ganglia, including Parkinson's disease. PMID:21307317

Anchoring Vignettes in the Health and Retirement Study: How Do Medical Professionals and Disability Recipients Characterize the Severity of Work Limitations?

PubMed Central

Heiland, Frank; Yin, Na

2015-01-01

Purpose Recent studies report systematic differences in how individuals categorize the severity of identical health and work limitation vignettes. We investigate how health professionals and disability recipients characterize the severity of work limitations and whether their reporting patterns are robust to demographic, education, and health characteristics. We use the results to illustrate the potential impact of reporting heterogeneity on the distribution of work disability estimated from self-reported categorical health and disability data. Method Nationally representative data on anchoring disability vignettes from the 2004 Health and Retirement Study (HRS) are used to investigate how respondents with an occupation background in health and Social Security disability beneficiaries categorize work limitation vignettes. Using pain, cardiovascular health, and depression vignettes, we estimate generalized ordered probit models (N = 2,660 individuals or 39,681 person-vignette observations) that allow the severity thresholds to vary by respondent characteristics. Results We find that health professionals (excluding nurses) and disability recipients tend to classify identical work limitations as more severe compared to non-health professional non-disabled respondents. For disability recipients, the differences are most pronounced and particularly visible in the tails of the work limitations distribution. For health professionals, we observe smaller differences, affecting primarily the classification of mildly and moderately severe work limitations. The patterns for health professionals (excluding nurses) are robust to demographics, education, and health conditions. The greater likelihood of viewing the vignette person as more severely work limited observed among disability recipients is mostly explained by the fact that these respondents also tend to be in poorer health which itself predicts a more inclusive scale. Conclusions Knowledge of reporting scales from health professionals and disabled individuals can benefit researchers in a broad range of applications in health and disability research. They may be useful as reference scales to evaluate disability survey data. Such knowledge may be beneficial when studying disability programs. Given the increasing availability of anchoring vignette data in surveys, this is a promising area for future evaluation research. PMID:25966316

Correlation transfer from basal ganglia to thalamus in Parkinson's disease

PubMed Central

Pamela, Reitsma; Brent, Doiron; Jonathan, Rubin

2011-01-01

Spike trains from neurons in the basal ganglia of parkinsonian primates show increased pairwise correlations, oscillatory activity, and burst rate compared to those from neurons recorded during normal brain activity. However, it is not known how these changes affect the behavior of downstream thalamic neurons. To understand how patterns of basal ganglia population activity may affect thalamic spike statistics, we study pairs of model thalamocortical (TC) relay neurons receiving correlated inhibitory input from the internal segment of the globus pallidus (GPi), a primary output nucleus of the basal ganglia. We observe that the strength of correlations of TC neuron spike trains increases with the GPi correlation level, and bursty firing patterns such as those seen in the parkinsonian GPi allow for stronger transfer of correlations than do firing patterns found under normal conditions. We also show that the T-current in the TC neurons does not significantly affect correlation transfer, despite its pronounced effects on spiking. Oscillatory firing patterns in GPi are shown to affect the timescale at which correlations are best transferred through the system. To explain this last result, we analytically compute the spike count correlation coefficient for oscillatory cases in a reduced point process model. Our analysis indicates that the dependence of the timescale of correlation transfer is robust to different levels of input spike and rate correlations and arises due to differences in instantaneous spike correlations, even when the long timescale rhythmic modulations of neurons are identical. Overall, these results show that parkinsonian firing patterns in GPi do affect the transfer of correlations to the thalamus. PMID:22355287

Human engineer's guide to auditory displays. Volume 2: Elements of signal reception and resolution affecting auditory displays

NASA Astrophysics Data System (ADS)

Mulligan, B. E.; Goodman, L. S.; McBride, D. K.; Mitchell, T. M.; Crosby, T. N.

1984-08-01

This work reviews the areas of monaural and binaural signal detection, auditory discrimination and localization, and reaction times to acoustic signals. The review was written from the perspective of human engineering and focuses primarily on auditory processing of information contained in acoustic signals. The impetus for this effort was to establish a data base to be utilized in the design and evaluation of acoustic displays. Appendix 1 also contains citations of the scientific literature on which was based the answers to each question. There are nineteen questions and answers, and more than two hundred citations contained in the list of references given in Appendix 2. This is one of two related works, the other of which reviewed the literature in the areas of auditory attention, recognition memory, and auditory perception of patterns, pitch, and loudness.

The power of sex: some reflections on the Caldwell's "African sexuality" thesis.

PubMed

Heald, S

1995-01-01

J.C. Caldwell et al. would like to construct a model of African society which is capable of generating ideas about the nature of sex behavior. Such a model would explain population and fertility patterns as well as those relevant to the spread of HIV. However, the author is concerned with the values and morality of sexuality in East Africa. She stresses that her intention is not to comprehensively rebut Caldwell's work, but simply to reflect upon the nature of sexuality in East Africa while drawing upon the works of Caldwell. The author's goal is to highlight areas of disagreement and to present and re-present evidence from the ethnographic record in order to move toward more satisfactory descriptive criteria with which to begin to think, as an anthropologist, about sexual morality in Africa. Sections consider Africa's alternative civilization, the lineage model, respect, the metaphor of mingling, affection, and alliance and contract.

Sleep, Dietary, and Exercise Behavioral Clusters among Truck Drivers with Obesity: Implications for Interventions

PubMed Central

Olson, Ryan; Thompson, Sharon V.; Wipfli, Brad; Hanson, Ginger; Elliot, Diane L.; Anger, W. Kent; Bodner, Todd; Hammer, Leslie B.; Hohn, Elliot; Perrin, Nancy A.

2015-01-01

Objective Our objectives were to describe a sample of truck drivers, identify clusters of drivers with similar patterns in behaviors affecting energy balance (sleep, diet, and exercise), and test for cluster differences in health and psychosocial factors. Methods Participants’ (n=452, BMI M=37.2, 86.4% male) self-reported behaviors were dichotomized prior to hierarchical cluster analysis, which identified groups with similar behavior co-variation. Cluster differences were tested with generalized estimating equations. Results Five behavioral clusters were identified that differed significantly in age, smoking status, diabetes prevalence, lost work days, stress, and social support, but not in BMI. Cluster 2, characterized by the best sleep quality, had significantly lower lost workdays and stress than other clusters. Conclusions Weight management interventions for drivers should explicitly address sleep, and may be maximally effective after establishing socially supportive work environments that reduce stress exposures. PMID:26949883

Effect of oxcarbazepine on sleep architecture.

PubMed

Ayala-Guerrero, Fructuoso; Mexicano, Graciela; González, Valentín; Hernandez, Mario

2009-07-01

The most common side effects following administration of antiepileptic drugs involve alterations in sleep architecture and varying degrees of daytime sleepiness. Oxcarbazepine is a drug that is approved as monotherapy for the treatment of partial seizures and generalized tonic-clonic seizures. However, there is no information about its effects on sleep pattern organization; therefore, the objective of this work was to analyze such effects. Animals (Wistar rats) exhibited three different behavioral and electrophysiological states of vigilance: wakefulness, slow wave sleep (SWS), and rapid eye movement (REM) sleep. Oral treatment with oxcarbazepine (100 mg/kg) produced an increment in total sleep time throughout the recording period. This increment involved both SWS and REM sleep. Mean duration of the REM sleep phase was not affected. In contrast, the frequency of this sleep phase increased significantly across the 10-hour period. REM sleep latency shortened significantly. Results obtained in this work indicate that oxcarbazepine's acute effects point to hypnotic properties.

Work-related productivity losses in an era of ageing populations: the case of colorectal cancer.

PubMed

Hanly, Paul; Walsh, Paul M; O Céilleachair, Alan; Skally, Mairead; Staines, Anthony; Kapur, Kanika; Fitzpatrick, Patricia; Sharp, Linda

2013-02-01

We investigated patterns and costs of lost productivity due to colorectal cancer in Ireland and examined how rising pension ages affect these costs. Data from a postal survey of colorectal cancer survivors (6 to 30 months after diagnosis; n = 159), taken from March 2010 to January 2011, were combined with population-level survival estimates and national wage data to calculate temporary and permanent disability, and premature mortality, costs using the human capital approach. Almost 40% of respondents left the workforce permanently after diagnosis and 90% took temporary time off work. Total costs of lost productivity per person were 205,847 in 2008 assuming retirement at the age of 65. When the retirement age was raised to 70, productivity costs increased by almost a half. Our study demonstrated the considerable productivity costs associated with colorectal cancer and highlighted the effect of rising retirement ages on costs.

The assessment of pharmaceutical sales representatives by family physicians--does it affect the prescribing index?

PubMed

Klemenc-Ketis, Zalika; Kersnik, Janko

2013-06-01

Physicians' prescribing patterns depend on fixed and influence-sensitive factors. The latter include the influence of interactions with the pharmaceutical industry. To determine whether the assessment of pharmaceutical sales representatives (PSRs) by family physicians was associated with their actual prescribing index. Cross-sectional anonymous postal study. We included all family physicians working in practice settings in Slovenia in 2011. Slovenian family physicians' surgeries. Prescribing index of Slovenian family physicians. We received 247 responses (27.6% response rate). A prescribing index >100% was present in 57 (23.1%) of the respondents. Multivariate analysis revealed that working in regions of Slovenia other than the central region might be associated with a prescribing index >100%. Assessment of PSRs by family physicians was not significantly associated with a prescribing index >100%. The assessment of PSRs by family physicians does not have any substantial correlations with their prescribing index.

Sleep, Dietary, and Exercise Behavioral Clusters Among Truck Drivers With Obesity: Implications for Interventions.

PubMed

Olson, Ryan; Thompson, Sharon V; Wipfli, Brad; Hanson, Ginger; Elliot, Diane L; Anger, W Kent; Bodner, Todd; Hammer, Leslie B; Hohn, Elliot; Perrin, Nancy A

2016-03-01

The objectives of the study were to describe a sample of truck drivers, identify clusters of drivers with similar patterns in behaviors affecting energy balance (sleep, diet, and exercise), and test for cluster differences in health safety, and psychosocial factors. Participants' (n = 452, body mass index M = 37.2, 86.4% male) self-reported behaviors were dichotomized prior to hierarchical cluster analysis, which identified groups with similar behavior covariation. Cluster differences were tested with generalized estimating equations. Five behavioral clusters were identified that differed significantly in age, smoking status, diabetes prevalence, lost work days, stress, and social support, but not in body mass index. Cluster 2, characterized by the best sleep quality, had significantly lower lost workdays and stress than other clusters. Weight management interventions for drivers should explicitly address sleep, and may be maximally effective after establishing socially supportive work environments that reduce stress exposures.

Gender at Work Within the Software Industry: AN Indian Perspective

NASA Astrophysics Data System (ADS)

Arun, Shoba; Arun, T. G.

Increasing globalization and the massive growth of the software Industry have created new opportunities for a skilled workforce in developing countries such as India. This study examines the impact of these changes on women's work in the state of Kerala, India, where there are high claims for social development, especially for women. The study indicates that although women tend to possess equal or better credentials than men, the nature of the labor market often renders it difficult for women to progress through their careers compared with men. The project-based,competltive nature of software development reproduces a masculine culture, which further interacts with the different career patterns of women and social norms and tends to disadvantage women. Most significantly, the centrality of social norms and gender ideologies within the workplace affects the Income and progression of women In the Internal labor market to a large extent.

Progesterone-dependent sexual behavior and protein patterns in the ventromedial hypothalamus of the adult female rat

DOE Office of Scientific and Technical Information (OSTI.GOV)

Montemayor, M.E.; Roy, E.J.; Giometti, C.S.

1994-09-01

Controversy exists concerning mechanisms by which progesterone exerts central nervous system effects on behavior. Progesterone may affect behavior by genomic regulation of protein synthesis. Alternatively, it may work through non-genomic mechanisms, consistent with its short latency to act. Recent work suggests that progesterone may elicit its effects on sexual behavior by more than one mechanism in a tissue specific manner. In the present study, we have examined whether progesterone facilitation of sexual behavior is correlated with modification of protein synthesis patterns in the ventromedial hypothalamus (VMH). Ovariectomized rats were divided into three groups: estradiol (4 ug/ka at 0 and 18more » hrs), estradiol (at 0 and 18 hrs) plus progesterone (2 mg/kg at 37 hrs), and vehicle only. {sup 35}S-labeled cysteine and methionine were bilaterally infused into the VMH at 37 hrs (the time of progesterone administration). Following 4 hrs of infusion, animals were tested for sexual behavior and sacrificed. Newly synthesized VMH proteins were separated by two dimensional gel electrophoresis followed by fluorography. Analysis of approximately 660 spots/fluorogram in two independent replications indicated that no protein was completely induced or lost as a result of being treated with progesterone. The abundances of several proteins were significantly altered in response to progesterone treatment in each replication; however, none were changed in abundance in both replications. These findings present no evidence that progesterone causes detectable alterations in VIMH protein patterns between 10-100 kDa in the 4.8-6.7 apparent pI range.« less

Emotion in languaging: languaging as affective, adaptive, and flexible behavior in social interaction

PubMed Central

Jensen, Thomas W.

2014-01-01

This article argues for a view on languaging as inherently affective. Informed by recent ecological tendencies within cognitive science and distributed language studies a distinction between first order languaging (language as whole-body sense making) and second order language (language as system like constraints) is put forward. Contrary to common assumptions within linguistics and communication studies separating language-as-a-system from language use (resulting in separations between language vs. body-language and verbal vs. non-verbal communication etc.) the first/second order distinction sees language as emanating from behavior making it possible to view emotion and affect as integral parts languaging behavior. Likewise, emotion and affect are studied, not as inner mental states, but as processes of organism-environment interactions. Based on video recordings of interaction between (1) children with special needs, and (2) couple in therapy and the therapist patterns of reciprocal influences between interactants are examined. Through analyzes of affective stance and patterns of inter-affectivity it is exemplified how language and emotion should not be seen as separate phenomena combined in language use, but rather as completely intertwined phenomena in languaging behavior constrained by second order patterns. PMID:25076921

Involvement of Working Memory in College Students' Sequential Pattern Learning and Performance

ERIC Educational Resources Information Center

Kundey, Shannon M. A.; De Los Reyes, Andres; Rowan, James D.; Lee, Bern; Delise, Justin; Molina, Sabrina; Cogdill, Lindsay

2013-01-01

When learning highly organized sequential patterns of information, humans and nonhuman animals learn rules regarding the hierarchical structures of these sequences. In three experiments, we explored the role of working memory in college students' sequential pattern learning and performance in a computerized task involving a sequential…

Testing a Conceptual Model of Working through Self-Defeating Patterns

ERIC Educational Resources Information Center

Wei, Meifen; Ku, Tsun-Yao

2007-01-01

The present study developed and examined a conceptual model of working through self-defeating patterns. Participants were 390 college students at a large midwestern university. Results indicated that self-defeating patterns mediated the relations between attachment and distress. Also, self-esteem mediated the link between self-defeating patterns…

Rocky intertidal zonation pattern in Antofagasta, chile: invasive species and shellfish gathering.

PubMed

Castilla, Juan Carlos; Manríquez, Patricio H; Delgado, Alejandro; Ortiz, Verónica; Jara, María Elisa; Varas, Manuel

2014-01-01

Biological invasions affecting rocky intertidal zonation patterns, yield information on species interactions. In the Bay of Antofagasta, northern Chile, the non-indigenous tunicate Pyura praeputialis, originally from Australia, has invaded (in the past century or so) and monopolized a major portion of the mid-intertidal rocky shore, displacing upshore the native mussel Perumytilus purpuratus. In Antofagasta the tunicate is subjected to intensive exploitation. Monitoring protocols show that in the past 10 years Antofagasta's tunicate population has experienced a drastic decline, affecting the intertidal zonation pattern. A 12.5 km of coastline, on the southern eastern shore of the Bay of Antofagasta, was studied. Eight sites were systematically (1993-1994) or sporadically (2003-2014) monitored for the seaward-shoreward expansion or reduction of the tunicate Pyura praeputialis, and native mussel and barnacle bands. A notable reduction in the mid-intertidal band of P. praeputialis and a seaward expansion of the mussel, Perumytilus purpuratus, and barnacle bands was observed. We suggest that the major cause for the decline in the tunicate is due to its intensive exploitation by rocky shore Pyura-gathers. The rate of extraction of tunicates by professional Pyura-gathers ranged between 256-740 tunicates hour-(1). Between 2009-2014 the density of professional Pyura-gather ranged between 0.5-4.5 km(-1) per low tide. Hence, 10 professional Pyura-gathers working 1 h for 10 low tides per month, during 6 months, will remove between 307-888 m(2) of tunicates. A drastic decline in tunicate recruitment was observed and several P. praeputialis ecosystems services have been lost. In Antofagasta, the continuous and intensive intertidal gathering of the invasive tunicate Pyura praeputialis, has caused a drastic reduction of its population modifying the zonation pattern. Thereby, native mussel Perumytilus purpuratus has regained its ecological center in the intertidal zone. We recorded a Pyura recruitment failure and loss of ecosystem services.

Determining the Effect of Natural Selection on Linked Neutral Divergence across Species

PubMed Central

Phung, Tanya N.; Lohmueller, Kirk E.

2016-01-01

A major goal in evolutionary biology is to understand how natural selection has shaped patterns of genetic variation across genomes. Studies in a variety of species have shown that neutral genetic diversity (intra-species differences) has been reduced at sites linked to those under direct selection. However, the effect of linked selection on neutral sequence divergence (inter-species differences) remains ambiguous. While empirical studies have reported correlations between divergence and recombination, which is interpreted as evidence for natural selection reducing linked neutral divergence, theory argues otherwise, especially for species that have diverged long ago. Here we address these outstanding issues by examining whether natural selection can affect divergence between both closely and distantly related species. We show that neutral divergence between closely related species (e.g. human-primate) is negatively correlated with functional content and positively correlated with human recombination rate. We also find that neutral divergence between distantly related species (e.g. human-rodent) is negatively correlated with functional content and positively correlated with estimates of background selection from primates. These patterns persist after accounting for the confounding factors of hypermutable CpG sites, GC content, and biased gene conversion. Coalescent models indicate that even when the contribution of ancestral polymorphism to divergence is small, background selection in the ancestral population can still explain a large proportion of the variance in divergence across the genome, generating the observed correlations. Our findings reveal that, contrary to previous intuition, natural selection can indirectly affect linked neutral divergence between both closely and distantly related species. Though we cannot formally exclude the possibility that the direct effects of purifying selection drive some of these patterns, such a scenario would be possible only if more of the genome is under purifying selection than currently believed. Our work has implications for understanding the evolution of genomes and interpreting patterns of genetic variation. PMID:27508305

Determining the Effect of Natural Selection on Linked Neutral Divergence across Species.

PubMed

Phung, Tanya N; Huber, Christian D; Lohmueller, Kirk E

2016-08-01

A major goal in evolutionary biology is to understand how natural selection has shaped patterns of genetic variation across genomes. Studies in a variety of species have shown that neutral genetic diversity (intra-species differences) has been reduced at sites linked to those under direct selection. However, the effect of linked selection on neutral sequence divergence (inter-species differences) remains ambiguous. While empirical studies have reported correlations between divergence and recombination, which is interpreted as evidence for natural selection reducing linked neutral divergence, theory argues otherwise, especially for species that have diverged long ago. Here we address these outstanding issues by examining whether natural selection can affect divergence between both closely and distantly related species. We show that neutral divergence between closely related species (e.g. human-primate) is negatively correlated with functional content and positively correlated with human recombination rate. We also find that neutral divergence between distantly related species (e.g. human-rodent) is negatively correlated with functional content and positively correlated with estimates of background selection from primates. These patterns persist after accounting for the confounding factors of hypermutable CpG sites, GC content, and biased gene conversion. Coalescent models indicate that even when the contribution of ancestral polymorphism to divergence is small, background selection in the ancestral population can still explain a large proportion of the variance in divergence across the genome, generating the observed correlations. Our findings reveal that, contrary to previous intuition, natural selection can indirectly affect linked neutral divergence between both closely and distantly related species. Though we cannot formally exclude the possibility that the direct effects of purifying selection drive some of these patterns, such a scenario would be possible only if more of the genome is under purifying selection than currently believed. Our work has implications for understanding the evolution of genomes and interpreting patterns of genetic variation.

Rocky Intertidal Zonation Pattern in Antofagasta, Chile: Invasive Species and Shellfish Gathering

PubMed Central

Castilla, Juan Carlos; Manríquez, Patricio H.; Delgado, Alejandro; Ortiz, Verónica; Jara, María Elisa; Varas, Manuel

2014-01-01

Background Biological invasions affecting rocky intertidal zonation patterns, yield information on species interactions. In the Bay of Antofagasta, northern Chile, the non-indigenous tunicate Pyura praeputialis, originally from Australia, has invaded (in the past century or so) and monopolized a major portion of the mid-intertidal rocky shore, displacing upshore the native mussel Perumytilus purpuratus. In Antofagasta the tunicate is subjected to intensive exploitation. Monitoring protocols show that in the past 10 years Antofagasta's tunicate population has experienced a drastic decline, affecting the intertidal zonation pattern. Methodology/Principal Findings A 12.5 km of coastline, on the southern eastern shore of the Bay of Antofagasta, was studied. Eight sites were systematically (1993–1994) or sporadically (2003–2014) monitored for the seaward-shoreward expansion or reduction of the tunicate Pyura praeputialis, and native mussel and barnacle bands. A notable reduction in the mid-intertidal band of P. praeputialis and a seaward expansion of the mussel, Perumytilus purpuratus, and barnacle bands was observed. We suggest that the major cause for the decline in the tunicate is due to its intensive exploitation by rocky shore Pyura-gathers. The rate of extraction of tunicates by professional Pyura-gathers ranged between 256–740 tunicates hour−1. Between 2009–2014 the density of professional Pyura-gather ranged between 0.5–4.5 km−1 per low tide. Hence, 10 professional Pyura-gathers working 1 h for 10 low tides per month, during 6 months, will remove between 307–888 m2 of tunicates. A drastic decline in tunicate recruitment was observed and several P. praeputialis ecosystems services have been lost. Conclusion and Significance In Antofagasta, the continuous and intensive intertidal gathering of the invasive tunicate Pyura praeputialis, has caused a drastic reduction of its population modifying the zonation pattern. Thereby, native mussel Perumytilus purpuratus has regained its ecological center in the intertidal zone. We recorded a Pyura recruitment failure and loss of ecosystem services. PMID:25338112

Vancomycin-Resistance Enterococci Infections in the Department of the Defense: Annual Report 2014

DTIC Science & Technology

2015-07-22

change in 2014 as VRE continues to predominately affect elderly females and manifest as urinary tract infections ( UTIs ). In addition, antibiotic...urinary tract infections ( UTIs ). In addition, antibiotic susceptibility patterns did not substantially change in 2014. Daptomycin, linezolid and...the infection continues to predominately affect elderly females and manifest as UTIs . In addition, antibiotic susceptibility patterns did not

Hummingbird conservation: discovering diversity patterns in southwest U.S.A.

Treesearch

Susan M. Wethington; George C. West; Barbara A. Carlson

2005-01-01

Using data obtained in 2002 and 2003 from sites in the Hummingbird Monitoring Network, we investigated the effect of geographic factors—latitude, longitude, and elevation—and year on hummingbird diversity patterns in Southwestern U.S.A. In California, none of these factors affected hummingbird richness but elevation significantly affected abundance. In southeastern...

Unravelling variation in feeding, social interaction and growth patterns among pigs using an agent-based model.

PubMed

Boumans, Iris J M M; de Boer, Imke J M; Hofstede, Gert Jan; Bokkers, Eddie A M

2018-07-01

Domesticated pigs, Sus scrofa, vary considerably in feeding, social interaction and growth patterns. This variation originates partly from genetic variation that affects physiological factors and partly from behavioural strategies (avoid or approach) in competitive food resource situations. Currently, it is unknown how variation in physiological factors and in behavioural strategies among animals contributes to variation in feeding, social interaction and growth patterns in animals. The aim of this study was to unravel causation of variation in these patterns among pigs. We used an agent-based model to explore the effects of physiological factors and behavioural strategies in pigs on variation in feeding, social interaction and growth patterns. Model results show that variation in feeding, social interaction and growth patterns are caused partly by chance, such as time effects and coincidence of conflicts. Furthermore, results show that seemingly contradictory empirical findings in literature can be explained by variation in pig characteristics (i.e. growth potential, positive feedback, dominance, and coping style). Growth potential mainly affected feeding and growth patterns, whereas positive feedback, dominance and coping style affected feeding patterns, social interaction patterns, as well as growth patterns. Variation in behavioural strategies among pigs can reduce aggression at group level, but also make some pigs more susceptible to social constraints inhibiting them from feeding when they want to, especially low-ranking pigs and pigs with a passive coping style. Variation in feeding patterns, such as feeding rate or meal frequency, can indicate social constraints. Feeding patterns, however, can say something different about social constraints at group versus individual level. A combination of feeding patterns, such as a decreased feed intake, an increased feeding rate, and an increased meal frequency might, therefore, be needed to measure social constraints at individual level. Copyright © 2018 Elsevier Inc. All rights reserved.

Are environmental characteristics in the municipal eldercare, more closely associated with frequent short sick leave spells among employees than with total sick leave: a cross-sectional study.

PubMed

Stapelfeldt, Christina Malmose; Nielsen, Claus Vinther; Andersen, Niels Trolle; Krane, Line; Fleten, Nils; Borg, Vilhelm; Jensen, Chris

2013-06-13

It has been suggested that frequent-, short-term sick leave is associated with work environment factors, whereas long-term sick leave is associated mainly with health factors. However, studies of the hypothesis of an association between a poor working environment and frequent short spells of sick leave are few and results are inconsistent. Therefore, we aimed to explore associations between self-reported psychosocial work factors and workplace-registered frequency and length of sick leave in the eldercare sector. Employees from the municipal eldercare in Aarhus (N = 2,534) were included. In 2005, they responded to a work environment questionnaire. Sick leave records from 2005 were dichotomised into total sick leave days (0-14 and above 14 days) and into spell patterns (0-2 short, 3-9 short, and mixed spells and 1-3 long spells). Logistic regression models were used to analyse associations; adjusted for age, gender, occupation, and number of spells or sick leave length. The response rate was 76%; 96% of the respondents were women. Unfavourable mean scores in work pace, demands for hiding emotions, poor quality of leadership and bullying were best indicated by more than 14 sick leave days compared with 0-14 sick leave days. For work pace, the best indicator was a long-term sick leave pattern compared with a non-frequent short-term pattern. A frequent short-term sick leave pattern was a better indicator of emotional demands (1.62; 95% CI: 1.1-2.5) and role conflict (1.50; 95% CI: 1.2-1.9) than a short-term non-frequent pattern.Age (= < 40 / >40 years) statistically significantly modified the association between the 1-3 long-term sick leave spell pattern and commitment to the workplace compared with the 3-9 frequent short-term pattern. Total sick leave length and a long-term sick leave spell pattern were just as good or even better indicators of unfavourable work factor scores than a frequent short-term sick leave pattern. Scores in commitment to the workplace and quality of leadership varied with sick leave pattern and age. Thus, different sick leave measures seem to be associated with different work environment factors. Further studies on these associations may inform interventions to improve occupational health care.

A complexity theory model in science education problem solving: random walks for working memory and mental capacity.

PubMed

Stamovlasis, Dimitrios; Tsaparlis, Georgios

2003-07-01

The present study examines the role of limited human channel capacity from a science education perspective. A model of science problem solving has been previously validated by applying concepts and tools of complexity theory (the working memory, random walk method). The method correlated the subjects' rank-order achievement scores in organic-synthesis chemistry problems with the subjects' working memory capacity. In this work, we apply the same nonlinear approach to a different data set, taken from chemical-equilibrium problem solving. In contrast to the organic-synthesis problems, these problems are algorithmic, require numerical calculations, and have a complex logical structure. As a result, these problems cause deviations from the model, and affect the pattern observed with the nonlinear method. In addition to Baddeley's working memory capacity, the Pascual-Leone's mental (M-) capacity is examined by the same random-walk method. As the complexity of the problem increases, the fractal dimension of the working memory random walk demonstrates a sudden drop, while the fractal dimension of the M-capacity random walk decreases in a linear fashion. A review of the basic features of the two capacities and their relation is included. The method and findings have consequences for problem solving not only in chemistry and science education, but also in other disciplines.

Primary health-care teams as adaptive organizations: exploring and explaining work variation using case studies in rural and urban Scotland.

PubMed

Farmer, Jane; West, Christina; Whyte, Bruce; Maclean, Margaret

2005-08-01

It is acknowledged, internationally, that health-care practitioners' work differs between and urban areas. While several factors affect individual teams' activities, there is little understanding about how patterns of work evolve. Consideration of work in relation to local circumstances is important for training, devising contracts and redesigning services. Six case studies centred on Scottish rural and urban general practices were used to examine, in-depth, the activity of primary health-care teams. Quantitative workload data about patient contacts were collected over 24 months. Interviews and diaries revealed insightful qualitative data. Findings revealed that rural general practitioners and district nurses tended to conduct more consultations per practice patient compared with their urban counterparts. Conditions seen and work tasks varied between case study teams. Qualitative data suggested that the key reasons for variation were: local needs and circumstances; choices made about deployment of available time, team composition and the extent of access to other services. Primary care teams might be viewed as adaptive organization, with co-evolution of services produced by health professionals and local people. The study highlights limitations in the application of workload data and suggests that understanding the nature of work in relation to local circumstances is important in service redesign.

Prevalence and Work-Relatedness of Carpal Tunnel Syndrome in the Working Population, United States, 2010 National Health Interview Survey

PubMed Central

Luckhaupt, Sara E.; Dahlhamer, James M.; Ward, Brian W.; Sweeney, Marie H.; Sestito, John P.; Calvert, Geoffrey M.

2015-01-01

Background Patterns of prevalence and work-relatedness of carpal tunnel syndrome (CTS) among workers offer clues about risk factors and targets for prevention. Methods Data from an occupational health supplement to the 2010 National Health Interview Survey were used to estimate the prevalence of self-reported clinician-diagnosed CTS overall and by demographic characteristics. The proportion of these cases self-reported to have been attributed to work by clinicians was also examined overall and by demographic characteristics. In addition, the distribution of industry and occupation (I&O) categories to which work-related cases of CTS were attributed was compared to the distribution of I&O categories of employment among current/recent workers. Results Data were available for 27,157 adults, including 17,524 current/recent workers. The overall lifetime prevalence of clinician-diagnosed CTS among current/recent workers was 6.7%. The 12-month prevalence was 3.1%, representing approximately 4.8 million workers with current CTS; 67.1% of these cases were attributed to work by clinicians, with overrepresentation of certain I&O categories. Conclusions CTS affected almost 5 million U.S. workers in 2010, with prevalence varying by demographic characteristics and I&O. PMID:22495886

Subtypes in bulimia nervosa: the role of eating disorder symptomatology, negative affect, and interpersonal functioning.

PubMed

Lunn, Susanne; Poulsen, Stig; Daniel, Sarah I F

2012-11-01

The aim of the study was to investigate whether patients with bulimia nervosa (BN) could be subdivided into clinically meaningful groups reflecting the complex patterns of eating disorder symptoms and personality characteristics that face the clinician. Seventy patients diagnosed with BN using the Eating Disorder Examination were assessed with measures of negative affect, attachment patterns, and interpersonal problems. An exploratory hierarchical cluster analysis was performed. The study found two main subtypes differing primarily in terms of symptom severity and level of negative affect, but these subtypes were further subdivided into four clinically relevant subtypes: A dietary restraint/negative affect/high symptomatic group, an emotionally overcontrolled group, a low dietary restraint/emotionally underregulated group, and a high functioning/securely attached group. The study indicates that cluster-analytic studies, including a broad range of instruments measuring eating disorder symptoms as well as negative affect, relational patterns, and other personality characteristics, may contribute to an integration of previously suggested models of subtypes in BN. Copyright © 2012 Elsevier Inc. All rights reserved.

Working the night shift: a necessary time for training or a risk to health and safety?

PubMed

Morrison, I; Flower, D; Hurley, J; McFadyen, R J

2013-01-01

The European Working Time Directive (EWTD) limits excessive night shifts and restricts the working week to no more than 48 hours. The underlying rationale is to minimise the health risks to all workers. Here we debate the impact of night rotas for doctors-in-training on patient safety and medical education; when the EWTD was agreed these topics may not have been considered, either systematically or objectively. The impacts of diurnal rhythms on human functions affect all night workers, but the nature of rostered medical and surgical work has little precedent in other industries or even in the contracts of other healthcare staff. For example, rostered night duties need to be distinguished from permanent night shift work. On-call medical night work from training doctors is generally required for short periods and usually involves fewer patients. It is an important time in training, where clinical responsibility and decision-making can be matured in a supervised setting. To comply with the EWTD most hospitals have adopted rota patterns that aim to cover the clinical needs, while ensuring no doctor works for more than 48 hours in an average working week. To monitor this process longterm studies are necessary to evaluate effects on a doctor's health and on patient care generally. The EWTD has also led to a loss of continuity of patient care; does this really matter?

Keeping up appearances: the role of identity concealment in the workplace among adults with degenerative eye conditions and its relationship with wellbeing and career outcomes.

PubMed

Spiegel, Tali; De Bel, Vera; Steverink, Nardi

2016-01-01

This study aims to describe the interplay between the work trajectories and the passing patterns of individuals with degenerative eye conditions in different phases of their career, as well as the disease progression and the career and well-being outcomes associated with different works and passing trajectories. Qualitative interviews on the topic of work trajectories were conducted with 36 working or retired individuals with degenerative eye conditions. The "bigger picture" method was used to explore passing and concealment behavioral patterns, and their associations with various work trajectories. Five patterns of passing and concealment behavior in the workplace were identified and were linked with various work trajectories among visually impaired study participants: (1) no career adjustments, concealed condition throughout career; (2) revealed condition after adjusting career plans; (3) increasingly open about their condition over the course of their career; (4) engaged in career planning, always open about their condition; and (5) engaged in limited career planning, always open about their condition. Patterns characterized by less planning and more identity concealment were associated with more stress and lower levels of self-acceptance, while patterns characterized by more planning for vision deterioration and less passing behavior were associated with higher levels self-acceptance and fewer obstacles over the course of an individual's career. The study's findings can serve as a guide for health professionals. Many individuals with degenerative eye conditions try to conceal their identity as visually impaired in the professional setting. Different aspects of career outcomes (e.g. age of retirement) and wellbeing outcomes (e.g. self-acceptance and stress) associate with identity concealment patterns of individuals throughout their careers. Identifying concealment patterns will allow health professionals to tackle particular adverse outcomes and challenges associated with these patterns.

Factors affecting the perception of Korean-accented American English

NASA Astrophysics Data System (ADS)

Cho, Kwansun; Harris, John G.; Shrivastav, Rahul

2005-09-01

This experiment examines the relative contribution of two factors, intonation and articulation errors, on the perception of foreign accent in Korean-accented American English. Ten native speakers of Korean and ten native speakers of American English were asked to read ten English sentences. These sentences were then modified using high-quality speech resynthesis techniques [STRAIGHT Kawahara et al., Speech Commun. 27, 187-207 (1999)] to generate four sets of stimuli. In the first two sets of stimuli, the intonation patterns of the Korean speakers and American speakers were switched with one another. The articulatory errors for each speaker were not modified. In the final two sets, the sentences from the Korean and American speakers were resynthesized without any modifications. Fifteen listeners were asked to rate all the stimuli for the degree of foreign accent. Preliminary results show that, for native speakers of American English, articulation errors may play a greater role in the perception of foreign accent than errors in intonation patterns. [Work supported by KAIM.

Characterization of the thin-film NbN superconductor for single-photon detection by transport measurements

NASA Astrophysics Data System (ADS)

Lin, Shi-Zeng; Ayala-Valenzuela, Oscar; McDonald, Ross D.; Bulaevskii, Lev N.; Holesinger, Terry G.; Ronning, Filip; Weisse-Bernstein, Nina R.; Williamson, Todd L.; Mueller, Alexander H.; Hoffbauer, Mark A.; Rabin, Michael W.; Graf, Matthias J.

2013-05-01

The fabrication of high-quality thin superconducting films is essential for single-photon detectors. Their device performance is crucially affected by their material parameters, thus requiring reliable and nondestructive characterization methods after the fabrication and patterning processes. Important material parameters to know are the resistivity, superconducting transition temperature, relaxation time of quasiparticles, and uniformity of patterned wires. In this work, we characterize micropatterned thin NbN films by using transport measurements in magnetic fields. We show that from the instability of vortex motion at high currents in the flux-flow state of the IV characteristic, the inelastic lifetime of quasiparticles can be determined to be about 2 ns. Additionally, from the depinning transition of vortices at low currents, as a function of magnetic field, the size distribution of grains can be extracted. This size distribution is found to be in agreement with the film morphology obtained from scanning electron microscopy and high-resolution transmission electron microscopy images.

Irrigant flow within a prepared root canal using various flow rates: a Computational Fluid Dynamics study.

PubMed

Boutsioukis, C; Lambrianidis, T; Kastrinakis, E

2009-02-01

To study using computer simulation the effect of irrigant flow rate on the flow pattern within a prepared root canal, during final irrigation with a syringe and needle. Geometrical characteristics of a side-vented endodontic needle and clinically realistic flow rate values were obtained from previous and preliminary studies. A Computational Fluid Dynamics (CFD) model was created using FLUENT 6.2 software. Calculations were carried out for five selected flow rates (0.02-0.79 mL sec(-1)) and velocity and turbulence quantities along the domain were evaluated. Irrigant replacement was limited to 1-1.5 mm apical to the needle tip for all flow rates tested. Low-Reynolds number turbulent flow was detected near the needle outlet. Irrigant flow rate affected significantly the flow pattern within the root canal. Irrigation needles should be placed to within 1 mm from working length to ensure fluid exchange. Turbulent flow of irrigant leads to more efficient irrigant replacement. CFD represents a powerful tool for the study of irrigation.

Long-term pattern and magnitude of soil carbon feedback to the climate system in a warming world.

PubMed

Melillo, J M; Frey, S D; DeAngelis, K M; Werner, W J; Bernard, M J; Bowles, F P; Pold, G; Knorr, M A; Grandy, A S

2017-10-06

In a 26-year soil warming experiment in a mid-latitude hardwood forest, we documented changes in soil carbon cycling to investigate the potential consequences for the climate system. We found that soil warming results in a four-phase pattern of soil organic matter decay and carbon dioxide fluxes to the atmosphere, with phases of substantial soil carbon loss alternating with phases of no detectable loss. Several factors combine to affect the timing, magnitude, and thermal acclimation of soil carbon loss. These include depletion of microbially accessible carbon pools, reductions in microbial biomass, a shift in microbial carbon use efficiency, and changes in microbial community composition. Our results support projections of a long-term, self-reinforcing carbon feedback from mid-latitude forests to the climate system as the world warms. Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Job insecurity and health.

PubMed

McDonough, P

2000-01-01

As employers respond to new competitive pressures of global capitalism through layoffs and the casualization of labor, job insecurity affects a growing number of workers. It appears to harm mental health, but less is known about its effects on physical health and health behaviors and the mechanisms through which it may act. The prevailing individual-centered conceptualization of job insecurity as the perception of a threat to job continuity precludes systematic investigation of the social patterning of its health effects. Analysis of data from a 1994 Canadian national probability sample of adults determined that high levels of job insecurity lowered self-rated health and increased distress and the use of medications, but had no impact on heavy drinking. The findings support one possible mechanism of action whereby job insecurity reduces feelings of control over one's environment and opportunities for positive self-evaluation; these psychological experiences, in turn, have deleterious health consequences. There is little evidence of social patterning of this relationship by gender, education, household income, age, marital status, and social support at work.

Residual currents and long-term transport

USGS Publications Warehouse

Cheng, R.T.

1990-01-01

Estuaries, bays, and contiguous coastal seas of the world are the most valuable and yet most vulnerable marine ecosystems. For centuries, society has placed enormous value on coastal areas for living, working, and recreation. In nearly all regions of the world, the largest population is distributed along the coastlines. The marine ecosystems provide food, shelter, and spawning grounds for fisheries, and refuge and sanctuary for wildlife. Dramatic increases in the population living in coastal regions have changed the pattern of land use and the movement of sediments. Obviously, these changes have not come without a price. Accompanying the coastal population increase is competition for the use of estuarine and coastal resources: the diversion of fresh water for irrigation and the discharge of waste water into these systems. The changing patterns of water use have resulted in deterioration of water quality, and in irreversible impacts on many marine ecosystems. All of these alterations directly affect the economic development and the quality of life in adjacent regions.

The impact of conscientiousness, mastery, and work circumstances on subsequent absenteeism in employees with and without affective disorders.

PubMed

Kok, Almar A L; Plaisier, Inger; Smit, Johannes H; Penninx, Brenda W J H

2017-03-29

High numbers of employees are coping with affective disorders. At the same time, ambitiousness, achievement striving and a strong sense of personal control and responsibility are personality characteristics that are nowadays regarded as key to good work functioning, whereas social work circumstances tend to be neglected. However, it is largely unkown how personality characteristics and work circumstances affect work functioning when facing an affective disorder. Given the high burden of affective disorders on occupational health, we investigate these issues in the context of affective disorders and absenteeism from work. The principal aim of this paper is to examine whether particular personality characteristics that reflect self-governance (conscientiousness and mastery) and work circumstances (demands, control, support) influence the impact of affective disorders on long-term absenteeism (>10 working days). Baseline and 1-year follow-up data from 1249 participants in the Netherlands Study of Depression and Anxiety (NESDA) in 2004-2006 was employed. Multivariate logistic regression analyses were performed, including interaction effects between depressive, anxiety, and comorbid disorders and personality and work circumstances. In general, mastery and conscientiousness increased nor diminished odds of subsequent long-term absenteeism, whereas higher job support significantly decreased these odds. Interaction effects showed that the impact of affective disorders on absenteeism was stronger for highly conscientious employees and for employees who experienced high job demands. Affective disorders may particularly severely affect work functioning of employees who are highly conscientious or face high psychological job demands. Adjusting working conditions to their individual needs may prevent excessive work absence.

76 FR 25277 - Examinations of Work Areas in Underground Coal Mines and Pattern of Violations

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-04

..., 1219-AB73 Examinations of Work Areas in Underground Coal Mines and Pattern of Violations AGENCY: Mine... four public hearings on the Agency's proposed rules for Examinations of Work Areas in Underground Coal... 1219-AB75'' for Examinations of Work Areas in Underground Coal Mines' submissions, and with ``RIN 1219...

Focusing on attention: the effects of working memory capacity and load on selective attention.

PubMed

Ahmed, Lubna; de Fockert, Jan W

2012-01-01

Working memory (WM) is imperative for effective selective attention. Distractibility is greater under conditions of high (vs. low) concurrent working memory load (WML), and in individuals with low (vs. high) working memory capacity (WMC). In the current experiments, we recorded the flanker task performance of individuals with high and low WMC during low and high WML, to investigate the combined effect of WML and WMC on selective attention. In Experiment 1, distractibility from a distractor at a fixed distance from the target was greater when either WML was high or WMC was low, but surprisingly smaller when both WML was high and WMC low. Thus we observed an inverted-U relationship between reductions in WM resources and distractibility. In Experiment 2, we mapped the distribution of spatial attention as a function of WMC and WML, by recording distractibility across several target-to-distractor distances. The pattern of distractor effects across the target-to-distractor distances demonstrated that the distribution of the attentional window becomes dispersed as WM resources are limited. The attentional window was more spread out under high compared to low WML, and for low compared to high WMC individuals, and even more so when the two factors co-occurred (i.e., under high WML in low WMC individuals). The inverted-U pattern of distractibility effects in Experiment 1, replicated in Experiment 2, can thus be explained by differences in the spread of the attentional window as a function of WM resource availability. The current findings show that limitations in WM resources, due to either WML or individual differences in WMC, affect the spatial distribution of attention. The difference in attentional constraining between high and low WMC individuals demonstrated in the current experiments helps characterise the nature of previously established associations between WMC and controlled attention.

Prevalence, pattern, and factors associated with work-related musculoskeletal disorders among pluckers in a tea plantation in Tamil Nadu, India

PubMed Central

Vasanth, Deepthi; Ramesh, Naveen; Fathima, Farah Naaz; Fernandez, Ria; Jennifer, Steffi; Joseph, Bobby

2015-01-01

Context: Musculoskeletal pain is common among tea leaf pluckers and is attributed to the load they carry, long working hours, the terrain, and insufficient job rotations. As a result of this, their health and work capacity are affected. Aims: To assess the prevalence, patterns, and factors associated with work-related musculoskeletal disorders (WRMDs) among pluckers in a tea plantation in Annamalai, Tamil Nadu, India. Settings and Design: This cross-sectional study surveyed 195 pluckers selected by simple random sampling aged between 18 years and 60 years. Materials and Methods: The interview schedule had four parts––sociodemographic detail, Standard Nordic Scale, numeric and facial pain rating tool, and a tool to assess factors associated with WRMDs. Statistical Analysis Used: Statistical Package for the Social Sciences (SPSS) version 16. Results: Prevalence of musculoskeletal pain in the last 12 months and the last 7 days was 83.6% and 78.5%, respectively. The most common site for last 1 year was shoulder (59%) and for last 7 days was the lower back (52.8%). Independent t-test revealed that the mean age of those with pain was 6.59 year more and mean years of employment was 1.38 years more among the workers with pain compared to workers without pain. Increasing morbidities among workers was also significantly associated with an increase in WRMDs on Chi-square test. Conclusions: The prevalence of musculoskeletal pain was high among tea pluckers and the most common site during the last 12 months and the last 7 days was the shoulder and lower back respectively was mild in character. Increase in age and duration of employment was associated with WRMDs. PMID:26957816

Recurrent, Robust and Scalable Patterns Underlie Human Approach and Avoidance

PubMed Central

Kennedy, David N.; Lehár, Joseph; Lee, Myung Joo; Blood, Anne J.; Lee, Sang; Perlis, Roy H.; Smoller, Jordan W.; Morris, Robert; Fava, Maurizio

2010-01-01

Background Approach and avoidance behavior provide a means for assessing the rewarding or aversive value of stimuli, and can be quantified by a keypress procedure whereby subjects work to increase (approach), decrease (avoid), or do nothing about time of exposure to a rewarding/aversive stimulus. To investigate whether approach/avoidance behavior might be governed by quantitative principles that meet engineering criteria for lawfulness and that encode known features of reward/aversion function, we evaluated whether keypress responses toward pictures with potential motivational value produced any regular patterns, such as a trade-off between approach and avoidance, or recurrent lawful patterns as observed with prospect theory. Methodology/Principal Findings Three sets of experiments employed this task with beautiful face images, a standardized set of affective photographs, and pictures of food during controlled states of hunger and satiety. An iterative modeling approach to data identified multiple law-like patterns, based on variables grounded in the individual. These patterns were consistent across stimulus types, robust to noise, describable by a simple power law, and scalable between individuals and groups. Patterns included: (i) a preference trade-off counterbalancing approach and avoidance, (ii) a value function linking preference intensity to uncertainty about preference, and (iii) a saturation function linking preference intensity to its standard deviation, thereby setting limits to both. Conclusions/Significance These law-like patterns were compatible with critical features of prospect theory, the matching law, and alliesthesia. Furthermore, they appeared consistent with both mean-variance and expected utility approaches to the assessment of risk. Ordering of responses across categories of stimuli demonstrated three properties thought to be relevant for preference-based choice, suggesting these patterns might be grouped together as a relative preference theory. Since variables in these patterns have been associated with reward circuitry structure and function, they may provide a method for quantitative phenotyping of normative and pathological function (e.g., psychiatric illness). PMID:20532247

Engagement in patterns of daily occupations and perceived health among women of working age.

PubMed

Håkansson, Carita; Lissner, Lauren; Björkelund, Cecilia; Sonn, Ulla

2009-05-01

The aim of the present cross-sectional study was to examine how subjective experiences of engagement in patterns of daily occupations (gainful employment, domestic work, enjoyable and recreational occupations) were associated with perceived health among women of working age. The sample (n=488) was drawn from a longitudinal cohort study of women of working age in Gothenburg, Sweden. Participants were women 38 (n=202) and 50 (n=286) years of age. They completed a questionnaire including questions about occupational experiences in relation to their patterns of daily occupations, perceived health, and socioeconomic factors. The results of the present study showed that a combination of different experience dimensions of patterns of daily occupations was associated with perceived health among women of working age, even when adjusted for socioeconomic factors and age. The results provided occupational pattern-related health indicators, i.e. manageability, personally meaningful occupations, and occupational balance. To combine these health indicators can be a way for occupational therapists to enable women to develop strategies to promote health and to prevent stress and sick leave.

On the Characterization of Revisitation Patterns in Complex Human Dynamics - A Data Science Approach

NASA Astrophysics Data System (ADS)

Barbosa Filho, Hugo Serrano

When it comes to visitation patterns, humans beings are extremely regular and predictable, with recurrent activities responsible for most of our movements. In recent years, we have seen scientists attempt to model and explain human dynamics and in particular human movement. Akin to other human behaviors, traveling patterns evolve from the convolution between internal and external factors. A better understanding on the mechanisms responsible for transforming and incorporating individual events into regular patterns is of fundamental importance. Many aspects of our complex lives are affected by human movements such as disease spread and epidemics modeling, city planning, wireless network development, and disaster relief, to name a few. Given the myriad of applications, it is clear that a complete understanding of how people move in space can lead to considerable benefits to our society. In most of the recent works, scientists have focused on the idea that people movements are biased towards frequently-visited locations. According to them, human movement is based on a exploration/exploitation dichotomy in which individuals choose new locations (exploration) or return to frequently-visited locations (exploitation). In this dissertation we present some of our contributions to the field, such as the presence of a recency effect in human mobility and Web browsing behaviors as well as the Returner vs. Explorers dichotomy in Web browsing trajectories.

Analysis of Stomata Distribution Patterns for Quantification of the Foliar Plasticity of Tradescantia Zebrina

NASA Astrophysics Data System (ADS)

Batista Florindo, Joao; Landini, Gabriel; Almeida Filho, Humberto; Martinez Bruno, Odemir

2015-09-01

Here we propose a method for the analysis of the stomata distribution patterns on the surface of plant leaves. We also investigate how light exposure during growth can affect stomata distribution and the plasticity of leaves. Understanding foliar plasticity (the ability of leaves to modify their structural organization to adapt to changing environmental resources) is a fundamental problem in Agricultural and Environmental Sciences. Most published work on quantification of stomata has concentrated on descriptions of their density per unit of leaf area, however density alone does not provide a complete description of the problem and leaves several unanswered questions (e.g. whether the stomata patterns change across various areas of the leaf, or how the patterns change under varying observational scales). We used two approaches here, to know, multiscale fractal dimension and complex networks, as a means to provide a description of the complexity of these distributions. In the experiments, we used 18 samples from the plant Tradescantia Zebrina grown under three different conditions (4 hours of artificial light each day, 24 hours of artificial light each day, and sunlight) for a total of 69 days. The network descriptors were capable of correctly discriminating the different conditions in 88% of cases, while the fractal descriptors discriminated 83% of the samples. This is a significant improvement over the correct classification rates achieved when using only stomata density (56% of the samples).

A hierarchical examination of methane uptake: field patterns, lab physiology, community composition and biogeography

NASA Astrophysics Data System (ADS)

von Fischer, J. C.; Koyama, A.; Johnson, N. G.; Webb, C. T.

2015-12-01

Scaling problems abound in biogeochemistry. At the finest scale, soil microbes experience habitats and environmental changes that affect the chemical transformations of interest. We collect the DNA of these organisms from sites across landscapes and note differences in who is there, and we seek to evaluate why group membership changes in space (biogeography) and why activity rates change over time (physiology). The goal of efforts at finer scales is often to better predict patterns at larger scales. We conducted such a hierarchical examination of methane uptake in the Great Plains grasslands of North America, gathering data from 22 plots at 8 field locations, scattered from South Dakota to New Mexico and Colorado to Kansas. Our work provides insight into methanotroph biogeochemistry at all of these scales. For example, we found that methane uptake rates vary mostly due to the methanotroph activity, and less so due to diffusivity. A combination of field and lab observations reveal that methanotroph communities differ in their sensitivity to soil moisture and to ammonium (an inhibitor of methanotrophy). Examination of methanotroph community composition reveals tantalizing patterns in composition, dominance and richness across sites, that appears to be structured by patterns of precipitation and soil texture. We anticipate that greater synthesis of these hierarchical findings will paint a richer picture of methanotroph life and enable improved prediction of methane uptake at regional scales.

Cross-language comparisons of contextual variation in the production and perception of vowels

NASA Astrophysics Data System (ADS)

Strange, Winifred

2005-04-01

In the last two decades, a considerable amount of research has investigated second-language (L2) learners problems with perception and production of non-native vowels. Most studies have been conducted using stimuli in which the vowels are produced and presented in simple, citation-form (lists) monosyllabic or disyllabic utterances. In my laboratory, we have investigated the spectral (static/dynamic formant patterns) and temporal (syllable duration) variation in vowel productions as a function of speech-style (list/sentence utterances), speaking rate (normal/rapid), sentence focus (narrow focus/post-focus) and phonetic context (voicing/place of surrounding consonants). Data will be presented for a set of languages that include large and small vowel inventories, stress-, syllable-, and mora-timed prosody, and that vary in the phonological/phonetic function of vowel length, diphthongization, and palatalization. Results show language-specific patterns of contextual variation that affect the cross-language acoustic similarity of vowels. Research on cross-language patterns of perceived phonetic similarity by naive listeners suggests that listener's knowledge of native language (L1) patterns of contextual variation influences their L1/L2 similarity judgments and subsequently, their discrimination of L2 contrasts. Implications of these findings for assessing L2 learners perception of vowels and for developing laboratory training procedures to improve L2 vowel perception will be discussed. [Work supported by NIDCD.

Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells.

PubMed

Ashapkin, V V; Linkova, N S; Khavinson, V Kh; Vanyushin, B F

2015-03-01

Expression levels of genes encoding specific transcription factors and other functionally important proteins vary upon aging of pancreatic and bronchial epithelium cell cultures. The peptides KEDW and AEDL tissue-specifically affect gene expression in pancreatic and bronchial cell cultures, respectively. It is established in this work that the DNA methylation patterns of the PDX1, PAX6, NGN3, NKX2-1, and SCGB1A1 gene promoter regions change upon aging in pancreatic and bronchial cell cultures in correlation with variations in their expression levels. Thus, stable changes in gene expression upon aging of cell cultures could be caused by changes in their promoter methylation patterns. The methylation patterns of the PAX4 gene in pancreatic cells as well as those of the FOXA1, SCGB3A2, and SFTPA1 genes in bronchial cells do not change upon aging and are unaffected by peptides, whereas their expression levels change in both cases. The promoter region of the FOXA2 gene in pancreatic cells contains a small number of methylated CpG sites, their methylation levels being affected by cell culture aging and KEDW, though without any correlation with gene expression levels. The promoter region of the FOXA2 gene is completely unmethylated in bronchial cells irrespective of cell culture age and AEDL action. Changes in promoter methylation might be the cause of age- and peptide-induced variations in expression levels of the PDX1, PAX6, and NGN3 genes in pancreatic cells and NKX2-1 and SCGB1A1 genes in bronchial cells. Expression levels of the PAX4 and FOXA2 genes in pancreatic cells and FOXA1, FOXA2, SCGB3A2, and SFTPA1 genes in bronchial cells seem to be controlled by some other mechanisms.

Emotion dysregulation and autonomic responses to film, rumination, and body awareness: Extending psychophysiological research to a naturalistic clinical setting and a chemically dependent female sample.

PubMed

Crowell, Sheila E; Price, Cynthia J; Puzia, Megan E; Yaptangco, Mona; Cheng, Sunny Chieh

2017-05-01

Substance use is a complex clinical problem characterized by emotion dysregulation and daily challenges that can interfere with laboratory research. Thus, few psychophysiological studies examine autonomic and self-report measures of emotion dysregulation with multidiagnostic, chemically dependent samples or extend this work into naturalistic settings. In this study, we used a within-subject design to examine changes in respiratory sinus arrhythmia (RSA), electrodermal activity (EDA), and self-reported affect across three tasks designed to elicit distinct psychophysiological and emotional response patterns. We also examined emotion dysregulation as a moderator of psychophysiological responses. Participants include 116 women with multiple comorbid mental health conditions enrolled in substance use treatment, many of whom also reported high emotion dysregulation. Participants were assessed in the treatment setting and completed three tasks: watching a sad movie clip, rumination on a stressful event, and a mindful interoceptive awareness meditation. Multilevel models were used to examine changes from resting baselines to the tasks. During the film, results indicate a significant decrease in RSA and an increase in EDA. For the rumination task, participants showed a decrease in RSA but no EDA response. For the body awareness task, there was an increase in RSA and a decrease in EDA. Emotion dysregulation was associated with differences in baseline RSA but not with EDA or with the slope of response patterns across tasks. Self-reported affect was largely consistent with autonomic patterns. Findings add to the literature on emotion dysregulation, substance use, and the translation of psychophysiological measurements into clinical settings with complex samples. © 2017 Society for Psychophysiological Research.

Paramecium swimming and ciliary beating patterns: a study on four RNA interference mutations.

PubMed

Funfak, Anette; Fisch, Cathy; Abdel Motaal, Hatem T; Diener, Julien; Combettes, Laurent; Baroud, Charles N; Dupuis-Williams, Pascale

2015-01-01

Paramecium cells swim and feed by beating their thousands of cilia in coordinated patterns. The organization of these patterns and its relationship with cell motility has been the subject of a large body of work, particularly as a model for ciliary beating in human organs where similar organization is seen. However the rapid motion of the cells makes quantitative measurements very challenging. Here we provide detailed measurements of the swimming of Paramecium cells from high-speed video at high magnification, as they move in microfluidic channels. An image analysis protocol allows us to decouple the cell movement from the motion of the cilia, thus allowing us to measure the ciliary beat frequency (CBF) and the spatio-temporal organization into metachronal waves along the cell periphery. Two distinct values of the CBF appear at different regions of the cell: most of the cilia beat in the range of 15 to 45 Hz, while the cilia in the peristomal region beat at almost double the frequency. The body and peristomal CBF display a nearly linear relation with the swimming velocity. Moreover the measurements do not display a measurable correlation between the swimming velocity and the metachronal wave velocity on the cell periphery. These measurements are repeated for four RNAi silenced mutants, where proteins specific to the cilia or to their connection to the cell base are depleted. We find that the mutants whose ciliary structure is affected display similar swimming to the control cells albeit with a reduced efficiency, while the mutations that affect the cilia's anchoring to the cell lead to strongly reduced ability to swim. This reduction in motility can be related to a loss of coordination between the ciliary beating in different parts of the cell.

Predominance and geo-mapping of avian influenza H5N1 in poultry sectors in Egypt.

PubMed

Arafa, Abdelsatar; El-Masry, Ihab; Khoulosy, Shereen; Hassan, Mohammed K; Soliman, Moussa; Fasanmi, Olubunmi G; Fasina, Folorunso O; Dauphin, Gwenaelle; Lubroth, Juan; Jobre, Yilma M

2016-11-28

Highly pathogenic avian influenza (HPAI) virus of the H5N1 subtype has been enzootic in the Egyptian poultry with significant human infections since 2008. This work evaluates the epidemiological and virological information from February 2006 to May 2015 in spatial and temporal terms. Only data with confirmed HPAI H5N1 sub-type were collected, and matched with the epidemiological data from various spatially and temporally-dispersed surveillances implemented between 2006 and 2015. Spatio-temporal analysis was conducted on a total of 3338 confirmed H5N1 HPAI poultry disease outbreaks and outputs described based on transmission patterns, poultry species, production types affected, trade, geographic and temporal distributions in Egypt. The H5N1 virus persists in the Egyptian poultry displaying a seasonal pattern with peak prevalence between January and March. There was no specific geographic pattern, but chickens and ducks were more affected. However, relatively higher disease incidences were recorded in the Nile Delta. Phylogenetic studies of the haemagglutinin gene sequences of H5N1 viruses indicated that multiple clusters circulated between 2006 and 2015, with significant deviations in circulation. Epidemiological dynamics of HPAI has changed with the origins of majority of outbreaks shifted to household poultry. The persistence of HPAI H5N1 in poultry with recurrent and sporadic infections in humans can influence virus evolution spatio-temporally. Household poultry plays significant roles in the H5N1 virus transmission to poultry and humans, but the role of commercial poultry needs further clarifications. While poultry trading supports the persistence and transmission of H5N1, the role of individual species may warrant further investigation. Surveillance activities, applying a multi-sectoral approach, are recommended.

Dim nighttime light impairs cognition and provokes depressive-like responses in a diurnal rodent.

PubMed

Fonken, Laura K; Kitsmiller, Emily; Smale, Laura; Nelson, Randy J

2012-08-01

Circadian disruption is a common by-product of modern life. Although jet lag and shift work are well-documented challenges to circadian organization, many more subtle environmental changes cause circadian disruption. For example, frequent fluctuations in the timing of the sleep/wake schedule, as well as exposure to nighttime lighting, likely affect the circadian system. Most studies of these effects have focused on nocturnal rodents, which are very different from diurnal species with respect to their patterns of light exposure and the effects that light can have on their activity. Thus, the authors investigated the effect of nighttime light on behavior and the brain of a diurnal rodent, the Nile grass rat. Following 3 weeks of exposure to standard light/dark (LD; 14:10 light [~150 lux] /dark [0 lux]) or dim light at night (dLAN; 14:10 light [~150 lux] /dim [5 lux]), rats underwent behavioral testing, and hippocampal neurons within CA1, CA3, and the dentate gyrus (DG) were examined. Three behavioral effects of dLAN were observed: (1) decreased preference for a sucrose solution, (2) increased latency to float in a forced swim test, and (3) impaired learning and memory in the Barnes maze. Light at night also reduced dendritic length in DG and basilar CA1 dendrites. Dendritic length in the DG positively correlated with sucrose consumption in the sucrose anhedonia task. Nighttime light exposure did not disrupt the pattern of circadian locomotor activity, and all grass rats maintained a diurnal activity pattern. Together, these data suggest that exposure to dLAN can alter affective responses and impair cognition in a diurnal animal.

Tomato Prenylated RAB Acceptor Protein 1 Modulates Trafficking and Degradation of the Pattern Recognition Receptor LeEIX2, Affecting the Innate Immune Response

PubMed Central

Pizarro, Lorena; Leibman-Markus, Meirav; Schuster, Silvia; Bar, Maya; Meltz, Tal; Avni, Adi

2018-01-01

Plants recognize microbial/pathogen associated molecular patterns (MAMP/PAMP) through pattern recognition receptors (PRRs) triggering an immune response against pathogen progression. MAMP/PAMP triggered immune response requires PRR endocytosis and trafficking for proper deployment. LeEIX2 is a well-known Solanum lycopersicum RLP-PRR, able to recognize and respond to the fungal MAMP/PAMP ethylene-inducing xylanase (EIX), and its function is highly dependent on intracellular trafficking. Identifying protein machinery components regulating LeEIX2 intracellular trafficking is crucial to our understanding of LeEIX2 mediated immune responses. In this work, we identified a novel trafficking protein, SlPRA1A, a predicted regulator of RAB, as an interactor of LeEIX2. Overexpression of SlPRA1A strongly decreases LeEIX2 endosomal localization, as well as LeEIX2 protein levels. Accordingly, the innate immune responses to EIX are markedly reduced by SlPRA1A overexpression, presumably due to a decreased LeEIX2 availability. Studies into the role of SlPRA1A in LeEIX2 trafficking revealed that LeEIX2 localization in multivesicular bodies/late endosomes is augmented by SlPRA1A. Furthermore, inhibiting vacuolar function prevents the LeEIX2 protein level reduction mediated by SlPRA1A, suggesting that SlPRA1A may redirect LeEIX2 trafficking to the vacuole for degradation. Interestingly, SlPRA1A overexpression reduces the amount of several RLP-PRRs, but does not affect the protein level of receptor-like kinase PRRs, suggesting a specific role of SlPRA1A in RLP-PRR trafficking and degradation. PMID:29545816

48 CFR 52.236-3 - Site Investigation and Conditions Affecting the Work.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Conditions Affecting the Work. 52.236-3 Section 52.236-3 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.236-3 Site Investigation and Conditions Affecting the Work. As prescribed in 36.503, insert the following clause: Site Investigation and Conditions Affecting the Work (APR 1984) (a) The...

Pattern of irritable bowel syndrome and its impact on quality of life in primary health care center attendees, Suez governorate, Egypt

PubMed Central

Abdulmajeed, Ahmed; Rabab, Mohamed A; Sliem, Hamdy A; Hebatallah, Nour Eldein

2011-01-01

Introduction Irritable bowel syndrome (IBS) is one of the most common disorders diagnosed by gastroenterologists and a common cause of general practice visits. Although this disease is not life threatening, patients with IBS seem to be seriously affected in their everyday life. The study was designed to explore the pattern of IBS in clinical practice and the impact on the quality of life. Methods This is a case control descriptive study. 117 individuals were included in this study. Rome II criteria were used for the diagnosis of IBS. Impact of IBS on patient's quality of life was determined by irritable bowel syndrome quality of life (IBS-QOL) questionnaire. Results Prevalence of IBS among the study sample was 34.2%. 10% were IBS-Diarrhea, 37.5% were IBS-Constipation and 52.5% were alternators. There is statistical insignificant relationship between IBS (+) and age while it was a significant relation regarding gender (more common among women 80%). There is statistical significance relationship between IBS (+) on one hand and marital status and occupational status on the other hand. Patients with IBS had statistically significant lower scores for all IBS- QOL domains compared with the control group. Conclusion IBS is a prevalent disorder that affects females more than males and it has significant impacts on work, lifestyle and social well-being. PMID:22145053

Pattern of irritable bowel syndrome and its impact on quality of life in primary health care center attendees, Suez governorate, Egypt.

PubMed

Abdulmajeed, Ahmed; Rabab, Mohamed A; Sliem, Hamdy A; Hebatallah, Nour Eldein

2011-01-01

Irritable bowel syndrome (IBS) is one of the most common disorders diagnosed by gastroenterologists and a common cause of general practice visits. Although this disease is not life threatening, patients with IBS seem to be seriously affected in their everyday life. The study was designed to explore the pattern of IBS in clinical practice and the impact on the quality of life. This is a case control descriptive study. 117 individuals were included in this study. Rome II criteria were used for the diagnosis of IBS. Impact of IBS on patient's quality of life was determined by irritable bowel syndrome quality of life (IBS-QOL) questionnaire. Prevalence of IBS among the study sample was 34.2%. 10% were IBS-Diarrhea, 37.5% were IBS-Constipation and 52.5% were alternators. There is statistical insignificant relationship between IBS (+) and age while it was a significant relation regarding gender (more common among women 80%). There is statistical significance relationship between IBS (+) on one hand and marital status and occupational status on the other hand. Patients with IBS had statistically significant lower scores for all IBS- QOL domains compared with the control group. IBS is a prevalent disorder that affects females more than males and it has significant impacts on work, lifestyle and social well-being.

Electrophysiological brain dynamics during the esthetic judgment of human bodies and faces.

PubMed

Muñoz, Francisco; Martín-Loeches, Manuel

2015-01-12

This experiment investigated how the esthetic judgment of human body and face modulates cognitive and affective processes. We hypothesized that judgments on ugliness and beauty would elicit separable event-related brain potentials (ERP) patterns, depending on the esthetic value of body and faces in both genders. In a pretest session, participants evaluated images in a range from very ugly to very beautiful, what generated three sets of beautiful, ugly and neutral faces and bodies. In the recording session, they performed a task consisting in a beautiful-neutral-ugly judgment. Cognitive and affective effects were observed on a differential pattern of ERP components (P200, P300 and LPC). Main findings revealed a P200 amplitude increase to ugly images, probably the result of a negativity bias in attentional processes. A P300 increase was found mostly to beautiful images, particularly to female bodies, consistent with the salience of these stimuli, particularly for stimulus categorization. LPC appeared significantly larger to both ugly and beautiful images, probably reflecting later, decision processes linked to keeping information in working memory. This finding was especially remarkable for ugly male faces. Our findings are discussed on the ground of evolutionary and adaptive value of esthetics in person evaluation. This article is part of a Special Issue entitled Hold Item. Copyright © 2014 Elsevier B.V. All rights reserved.

Universally Designed Text on the Web: Towards Readability Criteria Based on Anti-Patterns.

PubMed

Eika, Evelyn

2016-01-01

The readability of web texts affects accessibility. The Web Content Accessibility guidelines (WCAG) state that the recommended reading level should match that of someone who has completed basic schooling. However, WCAG does not give advice on what constitutes an appropriate reading level. Web authors need tools to help composing WCAG compliant texts, and specific criteria are needed. Classic readability metrics are generally based on lengths of words and sentences and have been criticized for being over-simplistic. Automatic measures and classifications of texts' reading levels employing more advanced constructs remain an unresolved problem. If such measures were feasible, what should these be? This work examines three language constructs not captured by current readability indices but believed to significantly affect actual readability, namely, relative clauses, garden path sentences, and left-branching structures. The goal is to see whether quantifications of these stylistic features reflect readability and how they correspond to common readability measures. Manual assessments of a set of authentic web texts for such uses were conducted. The results reveal that texts related to narratives such as children's stories, which are given the highest readability value, do not contain these constructs. The structures in question occur more frequently in expository texts that aim at educating or disseminating information such as strategy and journal articles. The results suggest that language anti-patterns hold potential for establishing a set of deeper readability criteria.

28nm node process optimization: a lithography centric view

NASA Astrophysics Data System (ADS)

Seltmann, Rolf

2014-10-01

Many experts claim that the 28nm technology node will be the most cost effective technology node forever. This results from primarily from the cost of manufacturing due to the fact that 28nm is the last true Single Patterning (SP) node. It is also affected by the dramatic increase of design costs and the limited shrink factor of the next following nodes. Thus, it is assumed that this technology still will be alive still for many years. To be cost competitive, high yields are mandatory. Meanwhile, leading edge foundries have optimized the yield of the 28nm node to such a level that that it is nearly exclusively defined by random defectivity. However, it was a long way to go to come to that level. In my talk I will concentrate on the contribution of lithography to this yield learning curve. I will choose a critical metal patterning application. I will show what was needed to optimize the process window to a level beyond the usual OPC model work that was common on previous nodes. Reducing the process (in particular focus) variability is a complementary need. It will be shown which improvements were needed in tooling, process control and design-mask-wafer interaction to remove all systematic yield detractors. Over the last couple of years new scanner platforms were introduced that were targeted for both better productivity and better parametric performance. But this was not a clear run-path. It needed some extra affords of the tool suppliers together with the Fab to bring the tool variability down to the necessary level. Another important topic to reduce variability is the interaction of wafer none-planarity and lithography optimization. Having an accurate knowledge of within die topography is essential for optimum patterning. By completing both the variability reduction work and the process window enhancement work we were able to transfer the original marginal process budget to a robust positive budget and thus ensuring high yield and low costs.

Voluntary Enhancement of Neural Signatures of Affiliative Emotion Using fMRI Neurofeedback

PubMed Central

Moll, Jorge; Weingartner, Julie H.; Bado, Patricia; Basilio, Rodrigo; Sato, João R.; Melo, Bruno R.; Bramati, Ivanei E.; de Oliveira-Souza, Ricardo; Zahn, Roland

2014-01-01

In Ridley Scott’s film “Blade Runner”, empathy-detection devices are employed to measure affiliative emotions. Despite recent neurocomputational advances, it is unknown whether brain signatures of affiliative emotions, such as tenderness/affection, can be decoded and voluntarily modulated. Here, we employed multivariate voxel pattern analysis and real-time fMRI to address this question. We found that participants were able to use visual feedback based on decoded fMRI patterns as a neurofeedback signal to increase brain activation characteristic of tenderness/affection relative to pride, an equally complex control emotion. Such improvement was not observed in a control group performing the same fMRI task without neurofeedback. Furthermore, the neurofeedback-driven enhancement of tenderness/affection-related distributed patterns was associated with local fMRI responses in the septohypothalamic area and frontopolar cortex, regions previously implicated in affiliative emotion. This demonstrates that humans can voluntarily enhance brain signatures of tenderness/affection, unlocking new possibilities for promoting prosocial emotions and countering antisocial behavior. PMID:24847819

Patterns in Nature Forming Patterns in Minds: An Evaluation of an Introductory Physics Unit

NASA Astrophysics Data System (ADS)

Sheaffer, Christopher Ryan

Educators are increasingly focused on the process over the content. In science especially, teachers want students to understand the nature of science and investigation. The emergence of scientific inquiry and engineering design teaching methods have led to the development of new teaching and evaluation methods that concentrate on steps in a process rather than facts in a topic. Research supports the notion that an explicit focus on the scientific process can lead to student science knowledge gains. In response to new research and standards many teachers have been developing teaching methods that seem to work well in their classrooms, but lack the time and resources to test them in other classroom environments. A high school Physics teacher (Bradford Hill) has developed a unit called Patterns in Nature (PIN) with objectives relating mathematical modeling to the scientific process. Designed for use in his large public school classroom, the unit was taken and used in a charter school with small classes. This study looks at specifically whether or not the PIN unit effectively teaches students how to graph the data they gather and fit an appropriate mathematical pattern, using that model to predict future measurements. Additionally, the study looks at the students' knowledge and views about the nature of science and the process of scientific investigation as it is affected by the PIN unit. Findings show that students are able to identify and apply patterns to data, but have difficulties explaining the meaning of the math. Students' show increases in their knowledge of the process of science, and the majority develop positive views about science in general. A major goal of this study is to place this unit in the cyclical process of Design-Based Research and allow for Pattern in Nature's continuous improvement, development and evaluation. Design-Based Research (DBR) is an approach that can be applied to the implementation and evaluation of classroom materials. This method incorporates the complexities of different contexts and changing treatments into the research methods and analysis. From the use of DBR teachers can understand more about how the designed materials affect the students. Others may be able to use the development and analysis of PIN study as a guide to look at similar aspects of science units developed elsewhere.

Modeling of gene expression pattern alteration by p,p′-DDE and dieldrin in largemouth bass

PubMed Central

Garcia-Reyero, Natàlia; Barber, David; Gross, Timothy; Denslow, Nancy

2007-01-01

In this study, largemouth bass (LMB) were subchronically exposed to p,p′-DDE or dieldrin in their diet to evaluate the effect of exposure on expression of genes involved in reproduction and steroid homeostasis. Using real-time PCR, we detected a different gene expression pattern for each OCP, suggesting that they each affect LMB in a different way. We also detected a different expression pattern among sexes, suggesting that sexes are affected differently by OCPs perhaps reflecting the different adaptive responses of each sex to dysregulation caused by OCP exposure. PMID:16707152

Modeling of gene expression pattern alteration by p,p′-DDE and dieldrin in largemouth bass

USGS Publications Warehouse

Garcia-Reyero, Natalia; Barber, David; Gross, Timothy; Denslow, Nancy

2006-01-01

In this study, largemouth bass (LMB) were subchronically exposed to p,p′-DDE or dieldrin in their diet to evaluate the effect of exposure on expression of genes involved in reproduction and steroid homeostasis. Using real-time PCR, we detected a different gene expression pattern for each OCP, suggesting that they each affect LMB in a different way. We also detected a different expression pattern among sexes, suggesting that sexes are affected differently by OCPs perhaps reflecting the different adaptive responses of each sex to dysregulation caused by OCP exposure.

Bursty communication patterns facilitate spreading in a threshold-based epidemic dynamics.

PubMed

Takaguchi, Taro; Masuda, Naoki; Holme, Petter

2013-01-01

Records of social interactions provide us with new sources of data for understanding how interaction patterns affect collective dynamics. Such human activity patterns are often bursty, i.e., they consist of short periods of intense activity followed by long periods of silence. This burstiness has been shown to affect spreading phenomena; it accelerates epidemic spreading in some cases and slows it down in other cases. We investigate a model of history-dependent contagion. In our model, repeated interactions between susceptible and infected individuals in a short period of time is needed for a susceptible individual to contract infection. We carry out numerical simulations on real temporal network data to find that bursty activity patterns facilitate epidemic spreading in our model.

The role of consolidation in learning context-dependent phonotactic patterns in speech and digital sequence production.

PubMed

Anderson, Nathaniel D; Dell, Gary S

2018-04-03

Speakers implicitly learn novel phonotactic patterns by producing strings of syllables. The learning is revealed in their speech errors. First-order patterns, such as "/f/ must be a syllable onset," can be distinguished from contingent, or second-order, patterns, such as "/f/ must be an onset if the vowel is /a/, but a coda if the vowel is /o/." A metaanalysis of 19 experiments clearly demonstrated that first-order patterns affect speech errors to a very great extent in a single experimental session, but second-order vowel-contingent patterns only affect errors on the second day of testing, suggesting the need for a consolidation period. Two experiments tested an analogue to these studies involving sequences of button pushes, with fingers as "consonants" and thumbs as "vowels." The button-push errors revealed two of the key speech-error findings: first-order patterns are learned quickly, but second-order thumb-contingent patterns are only strongly revealed in the errors on the second day of testing. The influence of computational complexity on the implicit learning of phonotactic patterns in speech production may be a general feature of sequence production.

Handler beliefs affect scent detection dog outcomes.

PubMed

Lit, Lisa; Schweitzer, Julie B; Oberbauer, Anita M

2011-05-01

Our aim was to evaluate how human beliefs affect working dog outcomes in an applied environment. We asked whether beliefs of scent detection dog handlers affect team performance and evaluated relative importance of human versus dog influences on handlers' beliefs. Eighteen drug and/or explosive detection dog/handler teams each completed two sets of four brief search scenarios (conditions). Handlers were falsely told that two conditions contained a paper marking scent location (human influence). Two conditions contained decoy scents (food/toy) to encourage dog interest in a false location (dog influence). Conditions were (1) control; (2) paper marker; (3) decoy scent; and (4) paper marker at decoy scent. No conditions contained drug or explosive scent; any alerting response was incorrect. A repeated measures analysis of variance was used with search condition as the independent variable and number of alerts as the dependent variable. Additional nonparametric tests compared human and dog influence. There were 225 incorrect responses, with no differences in mean responses across conditions. Response patterns differed by condition. There were more correct (no alert responses) searches in conditions without markers. Within marked conditions, handlers reported that dogs alerted more at marked locations than other locations. Handlers' beliefs that scent was present potentiated handler identification of detection dog alerts. Human more than dog influences affected alert locations. This confirms that handler beliefs affect outcomes of scent detection dog deployments.

Does a 3-week critical research appraisal course affect how students perceive their appraisal skills and the relevance of research for clinical practice? A repeated cross-sectional survey.

PubMed

Jelsness-Jørgensen, Lars-Petter

2015-01-01

Research utilisation is essential in developing evidence-based practices; although many students may be generally able to adopt such skills, there are reports of barriers related to critical appraisal skills. To explore how students perceive the relevance of research to future clinical practice and patients, and to what extent they read research (including reading pattern). Additionally, the objective was to explore whether a three-week intensive course in critical appraisal of research could affect these variables. A cross-sectional survey design, with a pre- and post-test. One large university college in Southeastern Norway. 196 multidisciplinary healthcare students at baseline and 147 after three weeks. A purposely-designed 21 item questionnaire was used to quantify students' attitudes towards using research and critical thinking. The questionnaire was based on themes emerging from prior focus group interviews with 10 nursing and social educator students as well as from the existing literature. At baseline, 6.1% and 7.1% of respondents perceived the research to be of little or very little importance for their future work and patients, respectively. Furthermore, 83.2% reported that they seldom or very seldom read scientific papers. At baseline, 40 different patterns of reading a scientific paper were identified. Additionally, 7.1% of respondents reported to read the introduction, methods and conclusion in combination. Significantly improved scores were found after completing the three-week course related to a) relevance of research for future work (p<0.01), b) self-perceived skills in critical appraisal (p<0.001), c) ability to find scientific papers (p≤0.01), and d) relevance of research for patients and users (p≤0.001). Teaching students' practical critical appraisal skills improved their view of the relevance of research for patients, future work as well as their own critical appraisal skills. Prospective studies are warranted to explore the effects of such teaching modules in the long-term. Copyright © 2014 Elsevier Ltd. All rights reserved.

Patterns of salivary cortisol levels can manifest work stress in emergency care providers.

PubMed

Nakajima, Yasushi; Takahashi, Takayuki; Shetty, Vivek; Yamaguchi, Masaki

2012-05-01

To develop objective assessments of work fatigue, we investigated the patterns of changes in salivary cortisol levels in emergency care providers working extended work shifts. Fourteen subjects, comprising seven physicians and seven physician assistants, provided unstimulated saliva samples at regular intervals over the course of a 24-h work shift and over their subsequent free day. There was a significant time effect, with early morning cortisol levels being significantly attenuated following the work shift. Native diurnal variations varied by gender, with the female subjects manifesting greater cortisol levels. Physicians also had higher cortisol profiles even though their wake-rest cycles were similar to those of the physician assistants. Our results suggest that temporal changes, as well as diurnal similarities, in the salivary cortisol patterns can reflect work-related stress and recovery. In particular, early morning cortisol levels may manifest individual reactivity to work stressors as well as sleep deprivation.

Patients' Characteristics Affecting Physician-Patient Nonverbal Communication.

ERIC Educational Resources Information Center

Street, Richard L.; Buller, David B.

1988-01-01

Examines the impact of patients' characteristics on patterns of nonverbal communication exhibited in physician-patient interactions at a family practice clinic. Finds some general patterns of nonverbal behavioral differences, consistency, and adaptation characterizing the entire data set, and that patients' characteristics influenced patterns of…

Memory functions in chronic pain: examining contributions of attention and age to test performance.

PubMed

Oosterman, Joukje M; Derksen, Laura C; van Wijck, Albert J M; Veldhuijzen, Dieuwke S; Kessels, Roy P C

2011-01-01

Previous studies have revealed that memory performance is diminished in chronic pain patients. Few studies, however, have assessed multiple components of memory in a single sample. It is currently also unknown whether attentional problems, which are commonly observed in chronic pain, mediate the decline in memory. Finally, previous studies have focused on middle-aged adults, and a possible detrimental effect of aging on memory performance in chronic pain patients has been commonly disregarded. This study, therefore, aimed at describing the pattern of semantic, working, and visual and verbal episodic memory performance in participants with chronic pain, while testing for possible contributions of attention and age to task performance. Thirty-four participants with chronic pain and 32 pain-free participants completed tests of episodic, semantic, and working memory to assess memory performance and a test of attention. Participants with chronic pain performed worse on tests of working memory and verbal episodic memory. A decline in attention explained some, but not all, group differences in memory performance. Finally, no additional effect of age on the diminished task performance in participants with chronic pain was observed. Taken together, the results indicate that chronic pain significantly affects memory performance. Part of this effect may be caused by underlying attentional dysfunction, although this could not fully explain the observed memory decline. An increase in age in combination with the presence of chronic pain did not additionally affect memory performance.

Seeing the world through rose-colored glasses: People who are happy and satisfied with life preferentially attend to positive stimuli.

PubMed

Raila, Hannah; Scholl, Brian J; Gruber, June

2015-08-01

Given the many benefits conferred by trait happiness and life satisfaction, a primary goal is to determine how these traits relate to underlying cognitive processes. For example, visual attention acts as a gateway to awareness, raising the question of whether happy and satisfied people attend to (and therefore see) the world differently. Previous work suggests that biases in selective attention are associated with both trait negativity and with positive affect states, but to our knowledge, no previous work has explored whether trait-happy individuals attend to the world differently. Here, we employed eye tracking as a continuous measure of sustained overt attention during passive viewing of displays containing positive and neutral photographs to determine whether selective attention to positive scenes is associated with measures of trait happiness and life satisfaction. Both trait measures were significantly correlated with selective attention for positive (vs. neutral) scenes, and this general pattern was robust across several types of positive stimuli (achievement, social, and primary reward), and not because of positive or negative state affect. Such effects were especially prominent during the later phases of sustained viewing. This suggests that people who are happy and satisfied with life may literally see the world in a more positive light, as if through rose-colored glasses. Future work should investigate the causal relationship between such attention biases and one's happiness and life satisfaction. (c) 2015 APA, all rights reserved).

The influence of daily sleep patterns of commercial truck drivers on driving performance.

PubMed

Chen, Guang Xiang; Fang, Youjia; Guo, Feng; Hanowski, Richard J

2016-06-01

Fatigued and drowsy driving has been found to be a major cause of truck crashes. Lack of sleep is the number one cause of fatigue and drowsiness. However, there are limited data on the sleep patterns (sleep duration, sleep percentage in the duration of non-work period, and the time when sleep occurred) of truck drivers in non-work periods and the impact on driving performance. This paper examined sleep patterns of 96 commercial truck drivers during non-work periods and evaluated the influence these sleep patterns had on truck driving performance. Data were from the Naturalistic Truck Driving Study. Each driver participated in the study for approximately four weeks. A shift was defined as a non-work period followed by a work period. A total of 1397 shifts were identified. Four distinct sleep patterns were identified based on sleep duration, sleep start/end point in a non-work period, and the percentage of sleep with reference to the duration of non-work period. Driving performance was measured by safety-critical events, which included crashes, near-crashes, crash-relevant conflicts, and unintentional lane deviations. Negative binomial regression was used to evaluate the association between the sleep patterns and driving performance, adjusted for driver demographic information. The results showed that the sleep pattern with the highest safety-critical event rate was associated with shorter sleep, sleep in the early stage of a non-work period, and less sleep between 1 a.m. and 5 a.m. This study also found that male drivers, with fewer years of commercial vehicle driving experience and higher body mass index, were associated with deteriorated driving performance and increased driving risk. The results of this study could inform hours-of-service policy-making and benefit safety management in the trucking industry. Published by Elsevier Ltd.

Mapping spatial patterns of people's risk perception of landslides

NASA Astrophysics Data System (ADS)

Kofler, Christian; Pedoth, Lydia; Elzbieta Stawinoga, Agnieszka; Schneiderbauer, Stefan

2016-04-01

The resilience of communities against natural hazards is largely influenced by how the individuals perceive risk. A good understanding of people's risk perception, awareness and hazard knowledge is crucial for developing and improving risk management and communication strategies between authorities and the affected population. A lot of research has been done in investigating the social aspects of risks to natural hazards by means of interviews or questionnaires. However, there is still a lack of research in the investigation of the influence of the spatial distance to a hazard event on peoples risk perception. While the spatial dimension of a natural hazard event is always assessed in works with a natural science approach, it is often neglected in works on social aspects of natural hazards. In the present study, we aimed to overcome these gaps by combining methods from different disciplines and assessing and mapping the spatial pattern of risk perception through multivariate statistical approaches based on empirical data from questionnaires. We will present results from a case study carried out in Badia, located in the Province of South Tyrol- Italy, where in December 2012 a landslide destroyed four residential buildings and led to the evacuation of 36 people. By means of questionnaires distributed to all adults living in the case study area we assessed people's risk perception and asked respondents to allocate their place of residence on a map of the case study area subdivided in 7 zones. Based on the data of the questionnaire results we developed a risk perception factor in order to express various assessed aspects linked to risk perception with one metric. We analyzed and mapped this factor according to the different zones reflecting the spatial distance to the event. Furthermore, a cluster analysis identified various risk behavior profiles within the population. We also investigated the spatial patterns of these risk profiles. We revealed that the residential zone in the immediate proximity to the landslide event showed significantly different results than all other zones. Though we have been able to observe spatial patterns of our developed metrics that changed significantly with geographic distance, our results led to the assumption that risk perception cannot be expressed in units of length. The appropriate spatial unit rather seems to be "immediate proximity" to the event. The results of our study can support response forces and authorities in planning and adopting different communication and management strategies tailored to different groups of affected persons.

Modeling forest harvesting effects on landscape pattern in the Northwest Wisconsin Pine Barrens

Treesearch

Volker C. Radeloff; David J. Mladenoff; Eric J. Gustafson; Robert M. Scheller; Patrick A. Zollner; Hong S. Heilman; H. Resit Akcakaya

2006-01-01

Forest management shapes landscape patterns, and these patterns often differ significantly from those typical for natural disturbance regimes. This may affect wildlife habitat and other aspects of ecosystem function. Our objective was to examine the effects of different forest management decisions on landscape pattern in a fire adapted ecosystem. We used a factorial...

Using pattern recognition as a method for predicting extreme events in natural and socio-economic systems

NASA Astrophysics Data System (ADS)

Intriligator, M.

2011-12-01

Vladimir (Volodya) Keilis-Borok has pioneered the use of pattern recognition as a technique for analyzing and forecasting developments in natural as well as socio-economic systems. Keilis-Borok's work on predicting earthquakes and landslides using this technique as a leading geophysicist has been recognized around the world. Keilis-Borok has also been a world leader in the application of pattern recognition techniques to the analysis and prediction of socio-economic systems. He worked with Allan Lichtman of American University in using such techniques to predict presidential elections in the U.S. Keilis-Borok and I have worked together with others on the use of pattern recognition techniques to analyze and to predict socio-economic systems. We have used this technique to study the pattern of macroeconomic indicators that would predict the end of an economic recession in the U.S. We have also worked with officers in the Los Angeles Police Department to use this technique to predict surges of homicides in Los Angeles.

Motion of the center of gravity of the body in clinical evaluation of gait.

PubMed

Tesio, L; Civaschi, P; Tessari, L

1985-04-01

The motion of the center of gravity during walking was analyzed in five hemiplegic subjects and eleven subjects affected by unilateral hip arthritis. In the hemiplegic subjects and 6 subjects with hip arthritis the transfer between kinetic and potential energy (with a passive pendular motion) was found to be 9-95% greater during the step performed on the affected limb ("pathological" step); as a consequence, the muscular work done during this step was 7-81% of the work done during the step performed on the second limb ("normal" step). Qualitatively similar gait anomalies were recorded in all hemiplegic subjects with hypertonus of the paretic limb: these subjects had to lift the spastic limb as a whole during the normal step, with the consequence that the center of gravity was lifted 0.6-3 cm more than during the pathological step. In contrast, various motor patterns were found in patients with hip arthritis. During the pathological step the center of gravity reached a height 0.5-3 cm greater in 7 subjects, 1 cm smaller in one subject, and about the same height reached during the normal step in 3 subjects. This was consistent with the various motor deficits caused by hip arthritis.

A neuropsychological comparison of obsessive-compulsive disorder and trichotillomania.

PubMed

Chamberlain, Samuel R; Fineberg, Naomi A; Blackwell, Andrew D; Clark, Luke; Robbins, Trevor W; Sahakian, Barbara J

2007-03-02

Obsessive-compulsive disorder (OCD) and trichotillomania (compulsive hair-pulling) share overlapping co-morbidity, familial transmission, and phenomenology. However, the extent to which these disorders share a common cognitive phenotype has yet to be elucidated using patients without confounding co-morbidities. To compare neurocognitive functioning in co-morbidity-free patients with OCD and trichotillomania, focusing on domains of learning and memory, executive function, affective processing, reflection-impulsivity and decision-making. Twenty patients with OCD, 20 patients with trichotillomania, and 20 matched controls undertook neuropsychological assessment after meeting stringent inclusion criteria. Groups were matched for age, education, verbal IQ, and gender. The OCD and trichotillomania groups were impaired on spatial working memory. Only OCD patients showed additional impairments on executive planning and visual pattern recognition memory, and missed more responses to sad target words than other groups on an affective go/no-go task. Furthermore, OCD patients failed to modulate their behaviour between conditions on the reflection-impulsivity test, suggestive of cognitive inflexibility. Both clinical groups showed intact decision-making and probabilistic reversal learning. OCD and trichotillomania shared overlapping spatial working memory problems, but neuropsychological dysfunction in OCD spanned additional domains that were intact in trichotillomania. Findings are discussed in relation to likely fronto-striatal neural substrates and future research directions.

Cognitive structure and the affective domain: on knowing and feeling in biology

NASA Astrophysics Data System (ADS)

Thompson, Tressa L.; Mintzes, Joel J.

2002-06-01

This cross-age study explored the structural complexity and propositional validity of knowledge about and attitudes toward sharks, and the relationships among knowledge and attitudes. Responses were elicited from a convenience sample of students (5th, 8th and 11th grade, and college level) and senior citizens (n = 238). All subjects constructed a concept map on sharks and responded to a Likert-type attitude inventory. Based on the work of Novak and Gowin (Leaning How to Learn, Cambridge University Press, 1984), concept maps were scored for frequencies of non-redundant concepts and scientifically valid relationships, levels of hierarchy, incidence of branching and number of crosslinks. The attitude inventory, emerging from Kellert's (The Value of Life: Biological Diversity and Human Society, Island Press, 1996) work, generated subscale scores on four affective dimensions: scientific, naturalistic, moralistic and utilitarian/negative. Significant differences were found among subject groups on all knowledge structure variables and attitudinal dimensions. Gender differences were documented on three of four attitude subscales. A series of simple, mulitiple and canonical correlations revealed moderately strong relationships between knowledge structure variables and attitudinal dimensions. The pattern of these relationships supports conservation education efforts and instructional practices that encourage meaningful learning, knowledge restructuring and conceptual change (Mintzes et al., Assessing Science Understanding: A Human Constructivist View, Academic Press, 2000).

Examining Teacher Talk in an Engineering Design-Based Science Curricular Unit

NASA Astrophysics Data System (ADS)

Aranda, Maurina L.; Lie, Richard; Selcen Guzey, S.; Makarsu, Murat; Johnston, Amanda; Moore, Tamara J.

2018-03-01

Recent science education reforms highlight the importance for teachers to implement effective instructional practices that promote student learning of science and engineering content and their practices. Effective classroom discussion has been shown to support the learning of science, but work is needed to examine teachers' enactment of engineering design-based science curricula by focusing on the content, complexity, structure, and orchestration of classroom discussions. In the present study, we explored teacher-student talk with respect to science in a middle school curriculum focused on genetics and genetic engineering. Our study was guided by the following major research question: What are the similarities and differences in teacher talk moves that occurred within an engineering design-based science unit enacted by two teachers? Through qualitative and quantitative approaches, we found that there were clear differences in two teachers' use of questioning strategies and presentation of new knowledge that affected the level of student involvement in classroom discourse and the richness and details of student contributions to the conversations. We also found that the verbal explanations of science content differed between two teachers. Collectively, the findings in this study demonstrate that although the teachers worked together to design an engineering designed-based science curriculum unit, their use of different discussion strategies and patterns, and interactions with students differed to affect classroom discourse.

Work routines moderate the association between eveningness and poor psychological well-being

PubMed Central

de Souza, Camila Morelatto; Hidalgo, Maria Paz Loayza

2018-01-01

Well-being is a useful screening method for the detection of mood disorders. Evidence associating psychological well-being with sleep-wake patterns exists, as well as associations with sleep-wake patterns, work-related parameters, and perceived self-efficacy. Despite the growing research regarding the relationship between these factors and mental health, there are few studies that analyze them together. OBJECTIVE: To investigate if the association between sleep-wake patterns and psychological well-being is mediated or moderated by perceived self-efficacy, work flexibility and work routines. MATERIAL AND METHODS: This cohort study was performed in southern Brazil. A sample of 987 individuals was analyzed (66.9% women; mean age = 43.9 years). Work routines parameters and work schedule flexibility were evaluated, most participants were farmers (46%) and most worked 7 days a week (69.1%). Munich Chronotype Questionnaire (MCTQ) was administered for evaluation of sleep-wake patterns, General Self-Efficacy Scale (GSE) for assessment the participants’ beliefs about how they coped with daily hassles, and World Health Organization Five-item Well-being Index (WHO-5) for evaluation of psychological well-being levels. Moderation and mediation models were tested. RESULTS: The moderation model showed influences of work end time on the relationship between sleep onset time and psychological well-being (R2 = 0.147; F = 24.16; p<0.001). The final regression model showed an association of psychological well-being with sex (Beta = -0.086; p = 0.004), sleep onset time (Beta = -0.086; p = 0.006), and self-efficacy (Beta = 0.316; p<0.001); the work end time showed association in the interaction with sleep onset time (Beta = -0.075; p = 0.016). CONCLUSION: The findings support the direct association of psychological well-being with sleep-wake patterns and self-efficacy, and show an interaction between work routines and sleep-wake patterns. Our results draw attention to the importance of the interplay between individual and social rhythms in relation to psychological well-being. PMID:29624593

Mid-cycle headaches and their relationship to different patterns of premenstrual stress symptoms.

PubMed

Kiesner, Jeff; Martin, Vincent T

2013-06-01

Recent research has shown that affective changes associated with the menstrual cycle may follow diverse patterns, including a classic premenstrual syndrome pattern, as well as the mirror opposite pattern, referred to as a mid-cycle pattern. Test for the presence of a mid-cycle pattern of headaches, in addition to a menstrual pattern and a noncyclic pattern; test for an association between experiencing a specific pattern of headaches and a specific (previously identified) pattern of depression/anxiety; and test for mean-level differences, across headache pattern groups, in average headache index and depression/anxiety scores (averaged across 2 menstrual cycles for each participant). A sample of 213 female university students completed daily questionnaires regarding symptoms of headaches and depression/anxiety for 2 menstrual cycles. Hierarchical linear modeling, polynomial multiple regression, analyses of variance, and chi-square analyses were used to test the hypotheses. Confirmed the existence of a mid-cycle pattern of headaches (16%), in addition to a menstrual pattern (51%), and a noncyclic pattern of headaches (33%). Patterns of headaches and affective change were significantly associated (χ(2) = 21.33, P = .0003; 54% correspondence), as were the average headache index and depression/anxiety scores (r = .49; P < .0001). No significant mean-level differences were found between the headache pattern groups on the average headache index scores or depression/anxiety scores. A significant number of women experience a mid-cycle pattern of headaches during the menstrual cycle. Moreover, women often, but not always, demonstrate the same pattern of headaches and depression/anxiety symptoms. © 2013 American Headache Society.

Working patterns and vitamin D status in mid-life: a cross-sectional study of the 1958 British birth cohort.

PubMed

Ward, Maria; Berry, Diane J; Power, Chris; Hyppönen, Elina

2011-12-01

To assess the association between working patterns and vitamin D status in men and women and to determine the potential influence of related lifestyle and socioeconomic factors. The authors used data from the 1958 British birth cohort (aged 45 years) and 6154 participants, who were in full-time work, were included in current analyses. Vitamin D status was measured by circulating concentrations of 25-hydroxyvitamin D (25(OH)D). Information on working patterns and lifestyle factors was obtained using a structured questionnaire administered at 45 years. Manual social class was strongly associated with vitamin D-related lifestyle factors, with those in manual classes not only spending more time outdoors, but also spending more time watching TV/using PC, consuming less supplements and oily fish. Associations between working patterns and vitamin D-related lifestyles were less clear: night work was not strongly associated with lifestyles in either gender, while working hours were associated with time spent outside, PC/TV leisure time and use of supplements in men but not in women. In men, working patterns were not associated with lower 25(OH)D concentrations. In women, 25(OH)D concentrations were 8% lower (95% CI 15% to 2%) in night workers compared with others, while women working less than 35 h/week had 5% higher concentrations of 25(OH)D (95% CI 1% to 8%) compared with those working 35-40 h/week after adjustment for season, social class and body mass index (BMI). Women working nights and longer hours may be vulnerable to deficits in vitamin D status and associated health hazards.

ARTIE: An Integrated Environment for the Development of Affective Robot Tutors

PubMed Central

Imbernón Cuadrado, Luis-Eduardo; Manjarrés Riesco, Ángeles; De La Paz López, Félix

2016-01-01

Over the last decade robotics has attracted a great deal of interest from teachers and researchers as a valuable educational tool from preschool to highschool levels. The implementation of social-support behaviors in robot tutors, in particular in the emotional dimension, can make a significant contribution to learning efficiency. With the aim of contributing to the rising field of affective robot tutors we have developed ARTIE (Affective Robot Tutor Integrated Environment). We offer an architectural pattern which integrates any given educational software for primary school children with a component whose function is to identify the emotional state of the students who are interacting with the software, and with the driver of a robot tutor which provides personalized emotional pedagogical support to the students. In order to support the development of affective robot tutors according to the proposed architecture, we also provide a methodology which incorporates a technique for eliciting pedagogical knowledge from teachers, and a generic development platform. This platform contains a component for identiying emotional states by analysing keyboard and mouse interaction data, and a generic affective pedagogical support component which specifies the affective educational interventions (including facial expressions, body language, tone of voice,…) in terms of BML (a Behavior Model Language for virtual agent specification) files which are translated into actions of a robot tutor. The platform and the methodology are both adapted to primary school students. Finally, we illustrate the use of this platform to build a prototype implementation of the architecture, in which the educational software is instantiated with Scratch and the robot tutor with NAO. We also report on a user experiment we carried out to orient the development of the platform and of the prototype. We conclude from our work that, in the case of primary school students, it is possible to identify, without using intrusive and expensive identification methods, the emotions which most affect the character of educational interventions. Our work also demonstrates the feasibility of a general-purpose architecture of decoupled components, in which a wide range of educational software and robot tutors can be integrated and then used according to different educational criteria. PMID:27536230

ARTIE: An Integrated Environment for the Development of Affective Robot Tutors.

PubMed

Imbernón Cuadrado, Luis-Eduardo; Manjarrés Riesco, Ángeles; De La Paz López, Félix

2016-01-01

Over the last decade robotics has attracted a great deal of interest from teachers and researchers as a valuable educational tool from preschool to highschool levels. The implementation of social-support behaviors in robot tutors, in particular in the emotional dimension, can make a significant contribution to learning efficiency. With the aim of contributing to the rising field of affective robot tutors we have developed ARTIE (Affective Robot Tutor Integrated Environment). We offer an architectural pattern which integrates any given educational software for primary school children with a component whose function is to identify the emotional state of the students who are interacting with the software, and with the driver of a robot tutor which provides personalized emotional pedagogical support to the students. In order to support the development of affective robot tutors according to the proposed architecture, we also provide a methodology which incorporates a technique for eliciting pedagogical knowledge from teachers, and a generic development platform. This platform contains a component for identiying emotional states by analysing keyboard and mouse interaction data, and a generic affective pedagogical support component which specifies the affective educational interventions (including facial expressions, body language, tone of voice,…) in terms of BML (a Behavior Model Language for virtual agent specification) files which are translated into actions of a robot tutor. The platform and the methodology are both adapted to primary school students. Finally, we illustrate the use of this platform to build a prototype implementation of the architecture, in which the educational software is instantiated with Scratch and the robot tutor with NAO. We also report on a user experiment we carried out to orient the development of the platform and of the prototype. We conclude from our work that, in the case of primary school students, it is possible to identify, without using intrusive and expensive identification methods, the emotions which most affect the character of educational interventions. Our work also demonstrates the feasibility of a general-purpose architecture of decoupled components, in which a wide range of educational software and robot tutors can be integrated and then used according to different educational criteria.

Socioeconomic and gender inequalities in job dissatisfaction among Japanese civil servants: the roles of work, family and personality characteristics.

PubMed

Sekine, Michikazu; Tatsuse, Takashi; Cable, Noriko; Chandola, Tarani; Marmot, Michael

2014-01-01

This study examines (1) whether there are employment grade and gender differences in job dissatisfaction and (2) whether work, family, and personality characteristics explain grade and gender differences in job dissatisfaction. The participants were 3,812 civil servants, aged 20-65, working at a local government in Japan. In both males and females, low control, low social support, work-to-family conflict, type A behaviour pattern and negative affectivity were significantly associated with job dissatisfaction. In females, high demands, long work hours and being unmarried were also associated with job dissatisfaction. Among males, in comparison with the highest grade employees, the age-adjusted odds ratio (OR) for job dissatisfaction in the lowest grade employees was 1.90 (95% CI: 1.40-2.59). The grade differences reduced to 1.08 (0.76-1.54) after adjustment for work, family and personality characteristics. Among females, similar grade differences were observed, although the differences were not statistically significant. In comparison with males, the age-adjusted OR in females for job dissatisfaction was 1.32 (1.14-1.52). This gender difference was reduced to 0.95 (0.79-1.14) following adjustment for the other factors. The majority of employees belong to low to middle grades, and female employees have increased. Reducing grade and gender differences in work and family characteristics is needed.

Patterns of Workplace Supervisor Support Desired by Abused Women

ERIC Educational Resources Information Center

Perrin, Nancy A.; Yragui, Nanette L.; Hanson, Ginger C.; Glass, Nancy

2011-01-01

The purpose of this study was to understand differences in patterns of supervisor support desired by female victims of intimate partner violence (IPV) and to examine whether the pattern of support desired at work is reflective of a woman's stage of change in the abusive relationship, IPV-related work interference, and IPV-related job reprimands or…

Spatial analysis of muscular activations in stroke survivors.

PubMed

Rasool, Ghulam; Afsharipour, Babak; Suresh, Nina L; Xiaogang Hu; Rymer, William Zev

2015-01-01

We investigated the spatial patterns of electrical activity in stroke-affected muscles using the high density surface electromyogram (sEMG) grids. We acquired 128-channel sEMG signals from the impaired as well as contralateral Biceps Brachii (BB) muscles of stroke survivors and from healthy participants at various force levels from 20 to 60% of maximum voluntary contraction in an isometric non-fatiguing recording protocol. We found the spatial sEMG pattern to be consistent across force levels in healthy and stroke subjects. However, once compared across sides (left vs right in healthy and impaired vs. contralateral in stroke) we found stroke-affected sides to be significantly different in distribution pattern of sEMG from the contralateral side. The sEMG activity areas were significantly shrunk on the affected sides indicating muscle atrophy due to stroke.

[Effect of alcohol on electrical organisation in the brain during a visuospatial working memory task and its relationship with the menstrual cycle].

PubMed

Sanz-Martin, Araceli; Hernández-González, Marisela; Guevara, Miguel Ángel; Santana, Gloria; Gumá-Díaz, Emilio

2014-02-01

The metabolism of alcohol and cognitive functions can vary during the menstrual cycle. Also, both alcohol ingestion and hormonal variations during menstruation have been associated with characteristic changes in electroencephalographic (EEG) activity. AIM. To determine whether EEG activity during a working memory task is affected by acute alcohol consumption, and if these EEG patterns vary in relation to different phases of the menstrual cycle. 24 women who drank a moderate dose of alcohol or placebo during the follicular and early luteal phases of the menstrual cycle. The EEG activity was recorded during performance of viso-spatial working memory task. Although the alcohol did not deteriorate the performance of working memory task, it caused in the EEG a decrease of relative theta power and lower right fronto-parietal correlation in theta and alpha2 bands. Only women who drank alcohol in the follicular phase had a higher relative potency of alpha1, which could indicate a lower level of arousal and attention. These results contribute to a better understanding of the brain mechanisms underlying cognitive changes with alcohol and its relationship to the menstrual cycle.

Mixed Emotions and Coping: The Benefits of Secondary Emotions

PubMed Central

Braniecka, Anna; Trzebińska, Ewa; Dowgiert, Aneta; Wytykowska, Agata

2014-01-01

The existing empirical literature suggests that during difficult situations, the concurrent experience of positive and negative affects may be ideal for ensuring successful adaptation and well-being. However, different patterns of mixed emotions may have different adaptive consequences. The present research tested the proposition that experiencing a pattern of secondary mixed emotion (i.e., secondary emotion that embrace both positive and negative affects) more greatly promotes adaptive coping than experiencing two other patterns of mixed emotional experiences: simultaneous (i.e., two emotions of opposing affects taking place at the same time) and sequential (i.e., two emotions of opposing affects switching back and forth). Support for this hypothesis was obtained from two experiments (Studies 1 and 2) and a longitudinal survey (Study 3). The results revealed that secondary mixed emotions predominate over sequential and simultaneous mixed emotional experiences in promoting adaptive coping through fostering the motivational and informative functions of emotions; this is done by providing solution-oriented actions rather than avoidance, faster decisions regarding coping strategies (Study 1), easier access to self-knowledge, and better narrative organization (Study 2). Furthermore, individuals characterized as being prone to feeling secondary mixed emotions were more resilient to stress caused by transitions than those who were characterized as being prone to feeling opposing emotions separately (Study 3). Taken together, the preliminary results indicate that the pattern of secondary mixed emotion provides individuals with a higher capacity to handle adversity than the other two patterns of mixed emotional experience. PMID:25084461

Mixed emotions and coping: the benefits of secondary emotions.

PubMed

Braniecka, Anna; Trzebińska, Ewa; Dowgiert, Aneta; Wytykowska, Agata

2014-01-01

The existing empirical literature suggests that during difficult situations, the concurrent experience of positive and negative affects may be ideal for ensuring successful adaptation and well-being. However, different patterns of mixed emotions may have different adaptive consequences. The present research tested the proposition that experiencing a pattern of secondary mixed emotion (i.e., secondary emotion that embrace both positive and negative affects) more greatly promotes adaptive coping than experiencing two other patterns of mixed emotional experiences: simultaneous (i.e., two emotions of opposing affects taking place at the same time) and sequential (i.e., two emotions of opposing affects switching back and forth). Support for this hypothesis was obtained from two experiments (Studies 1 and 2) and a longitudinal survey (Study 3). The results revealed that secondary mixed emotions predominate over sequential and simultaneous mixed emotional experiences in promoting adaptive coping through fostering the motivational and informative functions of emotions; this is done by providing solution-oriented actions rather than avoidance, faster decisions regarding coping strategies (Study 1), easier access to self-knowledge, and better narrative organization (Study 2). Furthermore, individuals characterized as being prone to feeling secondary mixed emotions were more resilient to stress caused by transitions than those who were characterized as being prone to feeling opposing emotions separately (Study 3). Taken together, the preliminary results indicate that the pattern of secondary mixed emotion provides individuals with a higher capacity to handle adversity than the other two patterns of mixed emotional experience.

THE ROLE OF AFFECTIVE EXPERIENCE IN WORK MOTIVATION

PubMed Central

SEO, MYEONG-GU; BARRETT, LISA FELDMAN; BARTUNEK, JEAN M.

2005-01-01

Based on psychological and neurobiological theories of core affective experience, we identify a set of direct and indirect paths through which affective feelings at work affect three dimensions of behavioral outcomes: direction, intensity, and persistence. First, affective experience may influence these behavioral outcomes indirectly by affecting goal level and goal commitment, as well as three key judgment components of work motivation: expectancy judgments, utility judgments, and progress judgments. Second, affective experience may also affect these behavioral outcomes directly. We discuss implications of our model. PMID:16871321

An investigation into how the European Working Time Directive has affected anaesthetic training.

PubMed

Bowhay, Andrew R

2008-08-12

The European Working Time Directive (EWTD) became law in 1993 but only applied to doctors in training in the United Kingdom in 2004. The trainees have in consequence had a reduction in their working hours but also a change to a shift pattern of working. For craft specialities, such as anaesthesia, there are concerns that a reduction in working hours has also led to a reduction in the time available for learning and that ultimately this may affect patient care. However, there is scant research on the perceptions of trainees concerning the impact of the EWTD on their training and working lives. This study investigated what the anaesthetic Specialist Registrars (SpRs) on the Mersey Deanery SpR rotation perceived to be training and also what effect the EWTD has had on that training and their quality of life, both within and outside work. The project was a cross sectional survey, using a quantitative questionnaire with qualitative free text comments which were aggregated into overarching themes and sub themes. 117 SpRs were sent questionnaires in April 2005; 73 completed questionnaires were returned (response rate 62.4%). Hierarchies of training opportunities emerged with training by consultants being most valued. 71.8% (95% CI 60.7-81.3) of trainees believed the EWTD has had a deleterious effect on their training and experience and 74.3% (95% CI 63.2-83.4) thought that they will be less prepared for a consultant post. 69.9% (95% CI 58.7-79.5) considered that their quality of life outside work had deteriorated, with only 15% (95% CI 8.3-24.6) finding improvement. 38.6% (95% CI 27.8-50.3) felt that they were not functioning as well as doctors, only 14.3% (95% CI 7.6-23.9) noting improvement. The trainees were still positive about anaesthesia and 73.2% (95% CI 62.2-82.5) would recommend this specialty to a student. The majority of anaesthetic SpRs in the Mersey Deanery have not welcomed the changes brought by the EWTD to their training, experience and quality of life outside work.

Sex differences in negative affect and lapse behavior during acute tobacco abstinence: a laboratory study.

PubMed

Pang, Raina D; Leventhal, Adam M

2013-08-01

Heightened negative affect during acute tobacco abstinence in women relative to men could be an important factor underlying sex differences in smoking motivation. However, little controlled experimental work addresses this hypothesis. The current study investigated sex differences in withdrawal-related negative affect, time to start smoking on a lab analogue smoking lapse task, and the interrelation between sex, withdrawal-related negative affect, and smoking lapse behavior. Following a baseline session, current smokers (women: n = 68, men: n = 131) attended two counterbalanced lab sessions (16 hours smoking abstinence and ad libitum smoking) during which they completed self-report measures of mood and withdrawal symptoms followed by a laboratory analogue smoking lapse task. In this task participants are monetarily rewarded for delaying smoking. Performance on this task serves as an analogue model of smoking lapse behavior by measuring smoker's capability to resist temptation to smoke under conditions where abstinence is advantageous. Females showed greater abstinence induced increases in composite negative affect as well as several particular negative affect states (i.e., POMS Anger, Anxiety, Depression, and Confusion, ps < .05) but no differences in abstinence induced changes in other forms of affect or craving. Females also exhibited marginally greater abstinence induced decreases in their willingness to delay smoking for money (p = .10), which was mediated by abstinence induced increases in anger (p < .05). These results suggest that differential sensitivity to abstinence induced negative affect, particularly anger, could underlie sex specific smoking patterns. Negative affect during tobacco abstinence may be an important factor for understanding and treating nicotine addiction in women. PsycINFO Database Record (c) 2013 APA, all rights reserved

Evaluating methods to visualize patterns of genetic differentiation on a landscape.

PubMed

House, Geoffrey L; Hahn, Matthew W

2018-05-01

With advances in sequencing technology, research in the field of landscape genetics can now be conducted at unprecedented spatial and genomic scales. This has been especially evident when using sequence data to visualize patterns of genetic differentiation across a landscape due to demographic history, including changes in migration. Two recent model-based visualization methods that can highlight unusual patterns of genetic differentiation across a landscape, SpaceMix and EEMS, are increasingly used. While SpaceMix's model can infer long-distance migration, EEMS' model is more sensitive to short-distance changes in genetic differentiation, and it is unclear how these differences may affect their results in various situations. Here, we compare SpaceMix and EEMS side by side using landscape genetics simulations representing different migration scenarios. While both methods excel when patterns of simulated migration closely match their underlying models, they can produce either un-intuitive or misleading results when the simulated migration patterns match their models less well, and this may be difficult to assess in empirical data sets. We also introduce unbundled principal components (un-PC), a fast, model-free method to visualize patterns of genetic differentiation by combining principal components analysis (PCA), which is already used in many landscape genetics studies, with the locations of sampled individuals. Un-PC has characteristics of both SpaceMix and EEMS and works well with simulated and empirical data. Finally, we introduce msLandscape, a collection of tools that streamline the creation of customizable landscape-scale simulations using the popular coalescent simulator ms and conversion of the simulated data for use with un-PC, SpaceMix and EEMS. © 2017 John Wiley & Sons Ltd.

[Geographic patterns and ecological factors correlates of snake species richness in China].

PubMed

Cai, Bo; Huang, Yong; Chen, Yue-Ying; Hu, Jun-Hua; Guo, Xian-Guang; Wang, Yue-Zhao

2012-08-01

Understanding large-scale geographic patterns of species richness as well its underlying mechanisms are among the most significant objectives of macroecology and biogeography. The ecological hypothesis is one of the most accepted explanations of this mechanism. Here, we studied the geographic patterns of snakes and investigated the relationships between species richness and ecological factors in China at a spatial resolution of 100 km×100 km. We obtained the eigenvector-based spatial filters by Principal Coordinates Neighbor Matrices, and then analyzed ecological factors by multiple regression analysis. The results indicated several things: (1) species richness of snakes showed multi-peak patterns along both the latitudinal and longitudinal gradient. The areas of highest richness of snake are tropics and subtropical areas of Oriental realm in China while the areas of lowest richness are Qinghai-Tibet Plateau, the grasslands and deserts in northern China, Yangtze-Huai Plain, Two-lake Plain, and the Poyang-lake Plain; (2) results of multiple regression analysis explained a total of 56.5% variance in snake richness. Among ecological factors used to explore the species richness patterns, we found the best factors were the normalized difference vegetation index, precipitation in the coldest quarter and temperature annual range ; (3) our results indicated that the model based on the significant variables that (P<0.05) uses a combination of precipitation of coldest quarter, normalized difference vegetation index and temperature annual range is the most parsimonious model for explaining the mechanism of snake richness in China. This finding demonstrates that different ecological factors work together to affect the geographic distribution of snakes in China. Studying the mechanisms that underlie these geographic patterns are complex, so we must carefully consider the choice of impact-factors and the influence of human activities.

SU-F-T-479: Estimation of the Accuracy in Respiratory-Gated Radiotherapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kurosawa, T; Miyakawa, S; Sato, M

Purpose: Irregular respiratory patterns affects dose outputs in respiratorygated radiotherapy and there is no commercially available quality assurance (QA) system for it. We designed and developed a patient specific QA system for respiratory-gated radiotherapy to estimate irradiated output. Methods: Our in-house QA system for gating was composed of a personal computer with the USB-FSIO electronic circuit connecting to the linear accelerator (ONCOR-K, Toshiba Medical Systems). The linac implements a respiratory gating system (AZ-733V, Anzai Medical). During the beam was on, 4.2 V square-wave pulses were continually sent to the system. Our system can receive and count the pulses. At first,more » our system and an oscilloscope were compared to check the performance of our system. Next, basic estimation models were generated when ionization-chamber measurements were performed in gating using regular sinusoidal wave patterns (2.0, 2.5, 4.0, 8.0, 15 sec/cycle). During gated irradiation with the regular patterns, the number of the pulses per one gating window was measured using our system. Correlation between the number of the pulses per one gating and dose per the gating window were assessed to generate the estimation model. Finally, two irregular respiratory patterns were created and the accuracy of the estimation was evaluated. Results: Compared to the oscilloscope, our system worked similarly. The basic models were generated with the accuracy within 0.1%. The results of the gated irradiations with two irregular respiratory patterns show good agreement within 0.4% estimation accuracy. Conclusion: Our developed system shows good estimation for even irregular respiration patterns. The system would be a useful tool to verify the output for respiratory-gated radiotherapy.« less

Personal Retirement Accounts and Saving†

PubMed Central

Aguila, Emma

2017-01-01

Aging populations are leading countries worldwide to social security reforms. Many countries are moving from pay-as-you-go to personal retirement account (PRA) systems because of their financial sustainability and positive impact on private savings. PRA systems boost private savings at a macro level by converting a government liability into financial wealth managed by private fund managers. However, at a micro level, changes in retirement wealth affect individuals' saving and consumption patterns through their working lives. Retirement wealth increased for lower-income workers after Mexico introduced PRAs, crowding out saving, increasing consumption, and offsetting some of the PRA effect on private savings. (JEL D14, E21, H55, J26, O16) PMID:28286607

Enantioselective Synthesis of 5,7-Bicyclic Ring Systems from Axially Chiral Allenes Using a Rh(I)-Catalyzed Cyclocarbonylation Reaction

PubMed Central

Grillet, Francois; Brummond, Kay M.

2013-01-01

A transfer of chirality in an intramolecular Rh(I)-catalyzed allenic Pauson-Khand reaction (APKR) to access tetrahydroazulenones, tetrahydrocyclopenta[c]azepinones and dihydrocyclopenta[c]oxepinones enantioselectively (22 – 99% ee) is described. The substitution pattern of the allene affected the transfer of chiral information. Complete transfer of chirality was obtained for all trisubstituted allenes, but loss of chiral information was observed for disubstituted allenes. This work constitutes the first demonstration of a transfer of chiral information from an allene to the 5-position of a cyclopentenone using a cyclocarbonylation reaction. The absolute configuration of the corresponding cyclocarbonylation product was also established, something that is rarely done. PMID:23485149

Understanding emotion with brain networks.

PubMed

Pessoa, Luiz

2018-02-01

Emotional processing appears to be interlocked with perception, cognition, motivation, and action. These interactions are supported by the brain's large-scale non-modular anatomical and functional architectures. An important component of this organization involves characterizing the brain in terms of networks. Two aspects of brain networks are discussed: brain networks should be considered as inherently overlapping (not disjoint) and dynamic (not static). Recent work on multivariate pattern analysis shows that affective dimensions can be detected in the activity of distributed neural systems that span cortical and subcortical regions. More broadly, the paper considers how we should think of causation in complex systems like the brain, so as to inform the relationship between emotion and other mental aspects, such as cognition.

Cognitive Modeling of Social Behaviors

NASA Technical Reports Server (NTRS)

Clancey, William J.; Sierhuis, Maarten; Damer. Bruce; Brodsky, Boris

2004-01-01

The driving theme of cognitive modeling for many decades has been that knowledge affects how and which goals are accomplished by an intelligent being (Newell 1991). But when one examines groups of people living and working together, one is forced to recognize that whose knowledge is called into play, at a particular time and location, directly affects what the group accomplishes. Indeed, constraints on participation, including roles, procedures, and norms, affect whether an individual is able to act at all (Lave & Wenger 1991; Jordan 1992; Scribner & Sachs 1991). To understand both individual cognition and collective activity, perhaps the greatest opportunity today is to integrate the cognitive modeling approach (which stresses how beliefs are formed and drive behavior) with social studies (which stress how relationships and informal practices drive behavior). The crucial insight is that norms are conceptualized in the individual &nd as ways of carrying out activities (Clancey 1997a, 2002b). This requires for the psychologist a shift from only modeling goals and tasks - why people do what they do - to modeling behavioral patterns-what people do-as they are engaged in purposeful activities. Instead of a model that exclusively deduces actions from goals, behaviors are also, if not primarily, driven by broader patterns of chronological and located activities (akin to scripts). This analysis is particular inspired by activity theory (Leont ev 1979). While acknowledging that knowledge (relating goals and operations) is fundamental for intelligent behavior, activity theory claims that a broader driver is the person s motives and conceptualization of activities. Such understanding of human interaction is normative (i.e., viewed with respect to social standards), affecting how knowledge is called into play and applied in practice. Put another way, how problems are discovered and framed, what methods are chosen, and indeed who even cares or has the authority to act, are all constrained by norms, which are conceived and enacted by individuals.

Are environmental characteristics in the municipal eldercare, more closely associated with frequent short sick leave spells among employees than with total sick leave: a cross-sectional study

PubMed Central

2013-01-01

Background It has been suggested that frequent-, short-term sick leave is associated with work environment factors, whereas long-term sick leave is associated mainly with health factors. However, studies of the hypothesis of an association between a poor working environment and frequent short spells of sick leave are few and results are inconsistent. Therefore, we aimed to explore associations between self-reported psychosocial work factors and workplace-registered frequency and length of sick leave in the eldercare sector. Methods Employees from the municipal eldercare in Aarhus (N = 2,534) were included. In 2005, they responded to a work environment questionnaire. Sick leave records from 2005 were dichotomised into total sick leave days (0–14 and above 14 days) and into spell patterns (0–2 short, 3–9 short, and mixed spells and 1–3 long spells). Logistic regression models were used to analyse associations; adjusted for age, gender, occupation, and number of spells or sick leave length. Results The response rate was 76%; 96% of the respondents were women. Unfavourable mean scores in work pace, demands for hiding emotions, poor quality of leadership and bullying were best indicated by more than 14 sick leave days compared with 0–14 sick leave days. For work pace, the best indicator was a long-term sick leave pattern compared with a non-frequent short-term pattern. A frequent short-term sick leave pattern was a better indicator of emotional demands (1.62; 95% CI: 1.1-2.5) and role conflict (1.50; 95% CI: 1.2-1.9) than a short-term non-frequent pattern. Age (= < 40 / >40 years) statistically significantly modified the association between the 1–3 long-term sick leave spell pattern and commitment to the workplace compared with the 3–9 frequent short-term pattern. Conclusions Total sick leave length and a long-term sick leave spell pattern were just as good or even better indicators of unfavourable work factor scores than a frequent short-term sick leave pattern. Scores in commitment to the workplace and quality of leadership varied with sick leave pattern and age. Thus, different sick leave measures seem to be associated with different work environment factors. Further studies on these associations may inform interventions to improve occupational health care. PMID:23764253

Popular Ideas, Attitudes, and Value Patterns Affecting Participation in Adult Literacy Programs in Slum Communities of Turkey: The Case of Nato Yolu Neighborhood

ERIC Educational Resources Information Center

Yildiz, Ahmet

2008-01-01

Despite the fact that there are nationwide literacy programs in Turkey in order to raise the literacy rate, the participation of illiterate individuals in these programs is not at a satisfactory level. This article is a study into the popular ideas, attitudes, and value patterns that negatively affect participation in literacy programs in a slum…

Plant species affect colonization patterns and metabolic activity of associated endophytes during phytoremediation of crude oil-contaminated soil.

PubMed

Fatima, K; Imran, A; Amin, I; Khan, Q M; Afzal, M

2016-04-01

Plants coupled with endophytic bacteria hold great potential for the remediation of polluted environment. The colonization patterns and activity of inoculated endophytes in rhizosphere and endosphere of host plant are among the primary factors that may influence the phytoremediation process. However, these colonization patterns and metabolic activity of the inoculated endophytes are in turn controlled by none other than the host plant itself. The present study aims to determine such an interaction specifically for plant-endophyte systems remediating crude oil-contaminated soil. A consortium (AP) of two oil-degrading endophytic bacteria (Acinetobacter sp. strain BRSI56 and Pseudomonas aeruginosa strain BRRI54) was inoculated to two grasses, Brachiaria mutica and Leptochloa fusca, vegetated in crude oil-contaminated soil. Colonization patterns and metabolic activity of the endophytes were monitored in the rhizosphere and endosphere of the plants. Bacterial augmentation enhanced plant growth and crude oil degradation. Maximum crude oil degradation (78%) was achieved with B. mutica plants inoculated with AP consortium. This degradation was significantly higher than those treatments, where plants and bacteria were used individually or L. fusca and endophytes were used in combination. Moreover, colonization and metabolic activity of the endophytes were higher in the rhizosphere and endosphere of B. mutica than L. fusca. The plant species affected not only colonization pattern and biofilm formation of the inoculated bacteria in the rhizosphere and endosphere of the host plant but also affected the expression of alkane hydroxylase gene, alkB. Hence, the investigation revealed that plant species can affect colonization patterns and metabolic activity of inoculated endophytic bacteria and ultimately the phytoremediation process.