Automatic gesture analysis using constant affine velocity.
Cifuentes, Jenny; Boulanger, Pierre; Pham, Minh Tu; Moreau, Richard; Prieto, Flavio
2014-01-01
Hand human gesture recognition has been an important research topic widely studied around the world, as this field offers the ability to identify, recognize, and analyze human gestures in order to control devices or to interact with computer interfaces. In particular, in medical training, this approach is an important tool that can be used to obtain an objective evaluation of a procedure performance. In this paper, some obstetrical gestures, acquired by a forceps, were studied with the hypothesis that, as the scribbling and drawing movements, they obey the one-sixth power law, an empirical relationship which connects path curvature, torsion, and euclidean velocity. Our results show that obstetrical gestures have a constant affine velocity, which is different for each type of gesture and based on this idea this quantity is proposed as an appropriate classification feature in the hand human gesture recognition field. PMID:25570332
Ligand Affinities Estimated by Quantum Chemical Calculations.
Söderhjelm, Pär; Kongsted, Jacob; Ryde, Ulf
2010-05-11
We present quantum chemical estimates of ligand-binding affinities performed, for the first time, at a level of theory for which there is a hope that dispersion and polarization effects are properly accounted for (MP2/cc-pVTZ) and at the same time effects of solvation, entropy, and sampling are included. We have studied the binding of seven biotin analogues to the avidin tetramer. The calculations have been performed by the recently developed PMISP approach (polarizable multipole interactions with supermolecular pairs), which treats electrostatic interactions by multipoles up to quadrupoles, induction by anisotropic polarizabilities, and nonclassical interactions (dispersion, exchange repulsion, etc.) by explicit quantum chemical calculations, using a fragmentation approach, except for long-range interactions that are treated by standard molecular-mechanics Lennard-Jones terms. In order to include effects of sampling, 10 snapshots from a molecular dynamics simulation are studied for each biotin analogue. Solvation energies are estimated by the polarized continuum model (PCM), coupled to the multipole-polarizability model. Entropy effects are estimated from vibrational frequencies, calculated at the molecular mechanics level. We encounter several problems, not previously discussed, illustrating that we are first to apply such a method. For example, the PCM model is, in the present implementation, questionable for large molecules, owing to the use of a surface definition that gives numerous small cavities in a protein. PMID:26615702
System for Estimating Horizontal Velocity During Descent
NASA Technical Reports Server (NTRS)
Johnson, Andrew; Cheng, Yang; Wilson, Reg; Goguen, Jay; Martin, Alejandro San; Leger, Chris; Matthies, Larry
2007-01-01
The descent image motion estimation system (DIMES) is a system of hardware and software, designed for original use in estimating the horizontal velocity of a spacecraft descending toward a landing on Mars. The estimated horizontal velocity is used in generating rocket-firing commands to reduce the horizontal velocity as part of an overall control scheme to minimize the landing impact. DIMES can also be used for estimating the horizontal velocity of a remotely controlled or autonomous aircraft for purposes of navigation and control.
Seismic velocity estimation from time migration
NASA Astrophysics Data System (ADS)
Cameron, M. K.; Fomel, S. B.; Sethian, J. A.
2007-08-01
We address the problem of estimating seismic velocities inside the Earth which is necessary for obtaining seismic images in regular Cartesian coordinates. The main goals are to develop algorithms to convert time-migration velocities to true seismic velocities, and to convert time-migrated images to depth images in regular Cartesian coordinates. Our main results are three-fold. First, we establish a theoretical relation between the true seismic velocities and the 'time-migration velocities' using the paraxial ray tracing. Second, we formulate an appropriate inverse problem describing the relation between time-migration velocities and depth velocities, and show that this problem is mathematically ill posed, i.e., unstable to small perturbations. Third, we develop numerical algorithms to solve regularized versions of these equations which can be used to recover smoothed velocity variations. Our algorithms consist of efficient time-to-depth conversion algorithms, based on Dijkstra-like fast marching methods, as well as level set and ray tracing algorithms for transforming Dix velocities into seismic velocities. Our algorithms are applied to both two-dimensional and three-dimensional problems, and we test them on a collection of both synthetic examples and field data.
Seismic velocity estimation from time migration
NASA Astrophysics Data System (ADS)
Cameron, Maria Kourkina
earth becomes horizontally nonconstant. Even mild lateral velocity variations can significantly distort subsurface structures on the time migrated images. Conversely, depth migration provides the potential for more accurate reconstructions, since it can handle significant lateral variations. However, this approach requires good input data, known as a "velocity model". We address the problem of estimating seismic velocities inside the earth, i.e., the problem of constructing a velocity model, which is necessary for obtaining seismic images in regular Cartesian coordinates. The main goals are to develop algorithms to convert time-migration velocities to true seismic velocities, and to convert time-migrated images to depth images in regular Cartesian coordinates. Our main results are three-fold. First, we establish a theoretical relation between the true seismic velocities and the "time migration velocities" using the paraxial ray tracing. Second, we formulate an appropriate inverse problem describing the relation between time migration velocities and depth velocities, and show that this problem is mathematically ill-posed, i.e., unstable to small perturbations. Third, we develop numerical algorithms to solve regularized versions of these equations which can be used to recover smoothed velocity variations. Our algorithms consist of efficient time-to-depth conversion algorithms, based on Dijkstra-like Fast Marching Methods, as well as level set and ray tracing algorithms for transforming Dix velocities into seismic velocities. Our algorithms are applied to both two-dimensional and three-dimensional problems, and we test them on a collection of both synthetic examples and field data.
Seismic velocity estimation from time migration
Cameron, Maria Kourkina
2007-01-01
earth becomes horizontally nonconstant. Even mild lateral velocity variations can significantly distort subsurface structures on the time migrated images. Conversely, depth migration provides the potential for more accurate reconstructions, since it can handle significant lateral variations. However, this approach requires good input data, known as a 'velocity model'. We address the problem of estimating seismic velocities inside the earth, i.e., the problem of constructing a velocity model, which is necessary for obtaining seismic images in regular Cartesian coordinates. The main goals are to develop algorithms to convert time-migration velocities to true seismic velocities, and to convert time-migrated images to depth images in regular Cartesian coordinates. Our main results are three-fold. First, we establish a theoretical relation between the true seismic velocities and the 'time migration velocities' using the paraxial ray tracing. Second, we formulate an appropriate inverse problem describing the relation between time migration velocities and depth velocities, and show that this problem is mathematically ill-posed, i.e., unstable to small perturbations. Third, we develop numerical algorithms to solve regularized versions of these equations which can be used to recover smoothed velocity variations. Our algorithms consist of efficient time-to-depth conversion algorithms, based on Dijkstra-like Fast Marching Methods, as well as level set and ray tracing algorithms for transforming Dix velocities into seismic velocities. Our algorithms are applied to both two-dimensional and three-dimensional problems, and we test them on a collection of both synthetic examples and field data.
Sound velocity estimation: A system theoretic approach
Candy, J.V.; Sullivan, E.J.
1993-07-30
A system-theoretic approach is proposed to investigate the feasibility of reconstructing a sound velocity profile (SVP) from acoustical hydrophone measurements. This problem is based on a state-space representation of the normal-mode propagation model. It is shown that this representation can be utilized to investigate the so-called observability of the SVP from noisy measurement data. A model-based processor is developed to extract this information and it is shown that even in cases where limited SVP information is available, the SVP can be estimated using this approach.
AN AFFINE-INVARIANT SAMPLER FOR EXOPLANET FITTING AND DISCOVERY IN RADIAL VELOCITY DATA
Hou Fengji; Hogg, David W.; Goodman, Jonathan; Weare, Jonathan; Schwab, Christian
2012-02-01
Markov chain Monte Carlo (MCMC) proves to be powerful for Bayesian inference and in particular for exoplanet radial velocity fitting because MCMC provides more statistical information and makes better use of data than common approaches like chi-square fitting. However, the nonlinear density functions encountered in these problems can make MCMC time-consuming. In this paper, we apply an ensemble sampler respecting affine invariance to orbital parameter extraction from radial velocity data. This new sampler has only one free parameter, and does not require much tuning for good performance, which is important for automatization. The autocorrelation time of this sampler is approximately the same for all parameters and far smaller than Metropolis-Hastings, which means it requires many fewer function calls to produce the same number of independent samples. The affine-invariant sampler speeds up MCMC by hundreds of times compared with Metropolis-Hastings in the same computing situation. This novel sampler would be ideal for projects involving large data sets such as statistical investigations of planet distribution. The biggest obstacle to ensemble samplers is the existence of multiple local optima; we present a clustering technique to deal with local optima by clustering based on the likelihood of the walkers in the ensemble. We demonstrate the effectiveness of the sampler on real radial velocity data.
An Affine-invariant Sampler for Exoplanet Fitting and Discovery in Radial Velocity Data
NASA Astrophysics Data System (ADS)
Hou, Fengji; Goodman, Jonathan; Hogg, David W.; Weare, Jonathan; Schwab, Christian
2012-02-01
Markov chain Monte Carlo (MCMC) proves to be powerful for Bayesian inference and in particular for exoplanet radial velocity fitting because MCMC provides more statistical information and makes better use of data than common approaches like chi-square fitting. However, the nonlinear density functions encountered in these problems can make MCMC time-consuming. In this paper, we apply an ensemble sampler respecting affine invariance to orbital parameter extraction from radial velocity data. This new sampler has only one free parameter, and does not require much tuning for good performance, which is important for automatization. The autocorrelation time of this sampler is approximately the same for all parameters and far smaller than Metropolis-Hastings, which means it requires many fewer function calls to produce the same number of independent samples. The affine-invariant sampler speeds up MCMC by hundreds of times compared with Metropolis-Hastings in the same computing situation. This novel sampler would be ideal for projects involving large data sets such as statistical investigations of planet distribution. The biggest obstacle to ensemble samplers is the existence of multiple local optima; we present a clustering technique to deal with local optima by clustering based on the likelihood of the walkers in the ensemble. We demonstrate the effectiveness of the sampler on real radial velocity data.
Zhao, Huaying; Fu, Yan; Glasser, Carla; Andrade Alba, Eric J; Mayer, Mark L; Patterson, George; Schuck, Peter
2016-01-01
The dynamic assembly of multi-protein complexes underlies fundamental processes in cell biology. A mechanistic understanding of assemblies requires accurate measurement of their stoichiometry, affinity and cooperativity, and frequently consideration of multiple co-existing complexes. Sedimentation velocity analytical ultracentrifugation equipped with fluorescence detection (FDS-SV) allows the characterization of protein complexes free in solution with high size resolution, at concentrations in the nanomolar and picomolar range. Here, we extend the capabilities of FDS-SV with a single excitation wavelength from single-component to multi-component detection using photoswitchable fluorescent proteins (psFPs). We exploit their characteristic quantum yield of photo-switching to imprint spatio-temporal modulations onto the sedimentation signal that reveal different psFP-tagged protein components in the mixture. This novel approach facilitates studies of heterogeneous multi-protein complexes at orders of magnitude lower concentrations and for higher-affinity systems than previously possible. Using this technique we studied high-affinity interactions between the amino-terminal domains of GluA2 and GluA3 AMPA receptors. DOI: http://dx.doi.org/10.7554/eLife.17812.001 PMID:27436096
Zhao, Huaying; Fu, Yan; Glasser, Carla; Andrade Alba, Eric J; Mayer, Mark L; Patterson, George; Schuck, Peter
2016-01-01
The dynamic assembly of multi-protein complexes underlies fundamental processes in cell biology. A mechanistic understanding of assemblies requires accurate measurement of their stoichiometry, affinity and cooperativity, and frequently consideration of multiple co-existing complexes. Sedimentation velocity analytical ultracentrifugation equipped with fluorescence detection (FDS-SV) allows the characterization of protein complexes free in solution with high size resolution, at concentrations in the nanomolar and picomolar range. Here, we extend the capabilities of FDS-SV with a single excitation wavelength from single-component to multi-component detection using photoswitchable fluorescent proteins (psFPs). We exploit their characteristic quantum yield of photo-switching to imprint spatio-temporal modulations onto the sedimentation signal that reveal different psFP-tagged protein components in the mixture. This novel approach facilitates studies of heterogeneous multi-protein complexes at orders of magnitude lower concentrations and for higher-affinity systems than previously possible. Using this technique we studied high-affinity interactions between the amino-terminal domains of GluA2 and GluA3 AMPA receptors. PMID:27436096
Estimating 2-D vector velocities using multidimensional spectrum analysis.
Oddershede, Niels; Løvstakken, Lasse; Torp, Hans; Jensen, Jørgen Arendt
2008-08-01
Wilson (1991) presented an ultrasonic wideband estimator for axial blood flow velocity estimation through the use of the 2-D Fourier transform. It was shown how a single velocity component was concentrated along a line in the 2-D Fourier space, where the slope was given by the axial velocity. Later, it was shown that this approach could also be used for finding the lateral velocity component by also including a lateral sampling. A single velocity component would then be concentrated along a plane in the 3-D Fourier space, tilted according to the 2 velocity components. This paper presents 2 new velocity estimators for finding both the axial and lateral velocity components. The estimators essentially search for the plane in the 3- D Fourier space, where the integrated power spectrum is largest. The first uses the 3-D Fourier transform to find the power spectrum, while the second uses a minimum variance approach. Based on this plane, the axial and lateral velocity components are estimated. Several phantom measurements, for flow-to-depth angles of 60, 75, and 90 degrees, were performed. Multiple parallel lines were beamformed simultaneously, and 2 different receive apodization schemes were tried. The 2 estimators were then applied to the data. The axial velocity component was estimated with an average standard deviation below 2.8% of the peak velocity, while the average standard deviation of the lateral velocity estimates was between 2.0% and 16.4%. The 2 estimators were also tested on in vivo data from a transverse scan of the common carotid artery, showing the potential of the vector velocity estimation method under in vivo conditions. PMID:18986918
Velocity estimation using optic flow and radar
NASA Astrophysics Data System (ADS)
Gerardi, Steven A.; Humbert, J. Sean; Pierce, Leland E.; Sarabandi, Kamal
2011-06-01
This paper presents the development of a static estimator for obtaining state information from optic flow and radar measurements. It is shown that estimates of translational and rotational speed can be extracted using a least squares inversion. The approach is demonstrated in a simulated three dimensional urban environment on an autonomous quadrotor micro-air-vehicle (MAV). The resulting methodology has the advantages of computation speed and simplicity, both of which are imperative for implementation on MAVs due to stringent size, weight, and power requirements.
Ultrasound imaging velocimetry: effect of beam sweeping on velocity estimation.
Zhou, Bin; Fraser, Katharine H; Poelma, Christian; Mari, Jean-Martial; Eckersley, Robert J; Weinberg, Peter D; Tang, Meng-Xing
2013-09-01
As an emerging flow-mapping tool that can penetrate deep into optically opaque media such as human tissue, ultrasound imaging velocimetry has promise in various clinical applications. Previous studies have shown that errors occur in velocity estimation, but the causes have not been well characterised. In this study, the error in velocity estimation resulting from ultrasound beam sweeping in image acquisition is quantitatively investigated. The effects on velocity estimation of the speed and direction of beam sweeping relative to those of the flow are studied through simulation and experiment. The results indicate that a relative error in velocity estimation of up to 20% can be expected. Correction methods to reduce the errors under steady flow conditions are proposed and evaluated. Errors in flow estimation under unsteady flow are discussed.
Anisotropic parameter estimation using velocity variation with offset analysis
Herawati, I.; Saladin, M.; Pranowo, W.; Winardhie, S.; Priyono, A.
2013-09-09
Seismic anisotropy is defined as velocity dependent upon angle or offset. Knowledge about anisotropy effect on seismic data is important in amplitude analysis, stacking process and time to depth conversion. Due to this anisotropic effect, reflector can not be flattened using single velocity based on hyperbolic moveout equation. Therefore, after normal moveout correction, there will still be residual moveout that relates to velocity information. This research aims to obtain anisotropic parameters, ε and δ, using two proposed methods. The first method is called velocity variation with offset (VVO) which is based on simplification of weak anisotropy equation. In VVO method, velocity at each offset is calculated and plotted to obtain vertical velocity and parameter δ. The second method is inversion method using linear approach where vertical velocity, δ, and ε is estimated simultaneously. Both methods are tested on synthetic models using ray-tracing forward modelling. Results show that δ value can be estimated appropriately using both methods. Meanwhile, inversion based method give better estimation for obtaining ε value. This study shows that estimation on anisotropic parameters rely on the accuracy of normal moveout velocity, residual moveout and offset to angle transformation.
Estimating propagation velocity through a surface acoustic wave sensor
Xu, Wenyuan; Huizinga, John S.
2010-03-16
Techniques are described for estimating the propagation velocity through a surface acoustic wave sensor. In particular, techniques which measure and exploit a proper segment of phase frequency response of the surface acoustic wave sensor are described for use as a basis of bacterial detection by the sensor. As described, use of velocity estimation based on a proper segment of phase frequency response has advantages over conventional techniques that use phase shift as the basis for detection.
A study of methods to estimate debris flow velocity
Prochaska, A.B.; Santi, P.M.; Higgins, J.D.; Cannon, S.H.
2008-01-01
Debris flow velocities are commonly back-calculated from superelevation events which require subjective estimates of radii of curvature of bends in the debris flow channel or predicted using flow equations that require the selection of appropriate rheological models and material property inputs. This research investigated difficulties associated with the use of these conventional velocity estimation methods. Radii of curvature estimates were found to vary with the extent of the channel investigated and with the scale of the media used, and back-calculated velocities varied among different investigated locations along a channel. Distinct populations of Bingham properties were found to exist between those measured by laboratory tests and those back-calculated from field data; thus, laboratory-obtained values would not be representative of field-scale debris flow behavior. To avoid these difficulties with conventional methods, a new preliminary velocity estimation method is presented that statistically relates flow velocity to the channel slope and the flow depth. This method presents ranges of reasonable velocity predictions based on 30 previously measured velocities. ?? 2008 Springer-Verlag.
Direct Estimation of the Rayleigh Wave Phase Velocity in Microtremors
NASA Astrophysics Data System (ADS)
Shiraishi, H.; Matsuoka, T.; Asanuma, H.
2005-12-01
The mictotremor survey method (MSM) is one of the techniques used to estimate the shear-wave velocity structure of sedimentary layers. In the MSM, inverse analysis of the dispersion of the phase velocity is used for the velocity modeling. The passive nature of the MSM brings time/cost advantages over other active survey techniques, and it has been used for the strong motion prediction in the sedimentary plains in Japan (Matsuoka et al., 2003).The Spatial autocorrelation (SPAC) method (Aki, 1957), where records from a circular array of evenly spaced sensors and a central sensor is analyzed, is one of the commonly used measurement/analysis techniques in the MSM. In this method, the directional average of complex coherence functions (CCFs) between the records at the center and the circumference is equal to the Bessel function of the first kind of zero order J0(ωr/c) (ω: angular frequency, r: radius of circular array, c: phase velocity), and, hence, the phase velocities can be estimated. However, in practice, the requirement for equally spaced sensor arrangement in the SPAC often restricts the observation sites especially in urban areas.The authors have newly derived a method to directly estimate J0(ωr/c) and the phase velocity with fewer restrictions on the sensor arrangements. In this method (the Direct Estimation Method: DEM), the Bessel function J0(ωr/c) is obtained as a solution of the simultaneous equations of the CCFs. We have also found on theoretical grounds that the sensor arrangement in the DEM is much more flexible than the SPAC. In practice sensors on the circumference can be set at almost any place as long as the overall arrangement has a symmetry. A field experiment has confirmed that the phase velocity determined from the DEM agreed with the phase velocity by the SPAC method.
Robust seismic velocity change estimation using ambient noise recordings
NASA Astrophysics Data System (ADS)
Daskalakis, E.; Evangelidis, C. P.; Garnier, J.; Melis, N. S.; Papanicolaou, G.; Tsogka, C.
2016-06-01
We consider the problem of seismic velocity change estimation using ambient noise recordings. Motivated by Zhan et al., we study how the velocity change estimation is affected by seasonal fluctuations in the noise sources. More precisely, we consider a numerical model and introduce spatio-temporal seasonal fluctuations in the noise sources. We show that indeed, as pointed out by Zhan et al., the stretching method is affected by these fluctuations and produces misleading apparent velocity variations which reduce dramatically the signal to noise ratio of the method. We also show that these apparent velocity variations can be eliminated by an adequate normalization of the cross-correlation functions. Theoretically we expect our approach to work as long as the seasonal fluctuations in the noise sources are uniform, an assumption which holds for closely located seismic stations. We illustrate with numerical simulations in homogeneous and scattering media that the proposed normalization significantly improves the accuracy of the velocity change estimation. Similar behaviour is also observed with real data recorded in the Aegean volcanic arc. We study in particular the volcano of Santorini during the seismic unrest of 2011-2012 and observe a decrease in the velocity of seismic waves which is correlated with GPS measured elevation.
Evaluation of the MV (CAPON) Coherent Doppler Lidar Velocity Estimator
NASA Technical Reports Server (NTRS)
Lottman, B.; Frehlich, R.
1997-01-01
The performance of the CAPON velocity estimator for coherent Doppler lidar is determined for typical space-based and ground-based parameter regimes. Optimal input parameters for the algorithm were determined for each regime. For weak signals, performance is described by the standard deviation of the good estimates and the fraction of outliers. For strong signals, the fraction of outliers is zero. Numerical effort was also determined.
Physiological responses at five estimates of critical velocity.
Bull, Anthony J; Housh, Terry J; Johnson, Glen O; Rana, Sharon R
2008-04-01
The purpose of this study was to compare critical velocity (CV) estimates from five mathematical models, and to examine the oxygen uptake (VO(2)) and heart rate (HR) responses during treadmill runs at the five estimates of CV. Ten subjects (six males and four females) performed one incremental test to determine maximal oxygen consumption (VO(2max)) and four or five randomly ordered constant-velocity trials on a treadmill for the estimation of CV. Five mathematical models were used to estimate CV for each subject including two linear, two nonlinear, and an exponential model. Up to five randomly ordered runs to exhaustion were performed by each subject at treadmill velocities that corresponded to the five CV estimates, and VO(2) and HR responses were monitored throughout each trial. The 3-parameter, nonlinear (Non-3) model produced CV estimates that were significantly (P < 0.05) less than the other four models. During runs at CV estimates, five subjects did not complete 60 min at the their estimate from the Non-3 model, nine did not complete 60 min at their estimate from the Non-2 model, and no subjects completed 60 min at any estimate from the other three models. The mean HR value (179 +/- 18 beats min(-1), HR(peak)) at the end of runs at CV using the Non-3 model was significantly less than the maximal HR (195 +/- 7 beats min(-1), HR(max)) achieved during the incremental trial to exhaustion. However, mean HR(peak) values from runs at all other CV estimates were not significantly different from HR(max). Furthermore, data indicated that mean HR(peak) values increased during runs at CV estimates from the third minute to the end of exercise for all models, and that these increases in VO(2) (range = 367-458 ml min(-1)) were significantly greater than that typically associated with O(2) drift ( approximately 200 ml min(-1)) for all but the exponential model, indicating a VO(2) slow component associated with CV estimates from four of the five models. However, the mean VO(2
Optical flow based velocity estimation for mobile robots
NASA Astrophysics Data System (ADS)
Li, Xiuzhi; Zhao, Guanrong; Jia, Songmin; Qin, Baoling; Yang, Ailin
2015-02-01
This paper presents an optical flow based novel technique to perceive the instant motion velocity of mobile robots. The primary focus of this study is to determine the robot's ego-motion using displacement field in temporally consecutive image pairs. In contrast to most previous approaches for estimating velocity, we employ a polynomial expansion based dense optical flow approach and propose a quadratic model based RANSAC refinement of flow fields to render our method more robust with respect to noise and outliers. Accordingly, techniques for geometrical transformation and interpretation of the inter-frame motion are presented. Advantages of our proposal are validated by real experimental results conducted on Pioneer robot.
Phased-array vector velocity estimation using transverse oscillations.
Pihl, Michael J; Marcher, Jonne; Jensen, Jorgen A
2012-12-01
A method for estimating the 2-D vector velocity of blood using a phased-array transducer is presented. The approach is based on the transverse oscillation (TO) method. The purposes of this work are to expand the TO method to a phased-array geometry and to broaden the potential clinical applicability of the method. A phased-array transducer has a smaller footprint and a larger field of view than a linear array, and is therefore more suited for, e.g., cardiac imaging. The method relies on suitable TO fields, and a beamforming strategy employing diverging TO beams is proposed. The implementation of the TO method using a phased-array transducer for vector velocity estimation is evaluated through simulation and flow-rig measurements are acquired using an experimental scanner. The vast number of calculations needed to perform flow simulations makes the optimization of the TO fields a cumbersome process. Therefore, three performance metrics are proposed. They are calculated based on the complex TO spectrum of the combined TO fields. It is hypothesized that the performance metrics are related to the performance of the velocity estimates. The simulations show that the squared correlation values range from 0.79 to 0.92, indicating a correlation between the performance metrics of the TO spectrum and the velocity estimates. Because these performance metrics are much more readily computed, the TO fields can be optimized faster for improved velocity estimation of both simulations and measurements. For simulations of a parabolic flow at a depth of 10 cm, a relative (to the peak velocity) bias and standard deviation of 4% and 8%, respectively, are obtained. Overall, the simulations show that the TO method implemented on a phased-array transducer is robust with relative standard deviations around 10% in most cases. The flow-rig measurements show similar results. At a depth of 9.5 cm using 32 emissions per estimate, the relative standard deviation is 9% and the relative bias is -9
Estimating groundwater velocity using apparent resistivity tomography: A sandbox experiment
NASA Astrophysics Data System (ADS)
Chen, J. L.; Chen, C. H.; Kuo, C. L.; Fen, C. S.; Wu, C. C.
2016-08-01
The electrical resistivity tomography (ERT) technique can estimate groundwater velocity to within 5% of the pre-set groundwater velocity. The apparent conductivity obtained by the ERT technique is linearly related to the groundwater conductivity, as described by Archie's law. Gaussian-like profiles of the tracer concentration were demonstrated with the ERT technique, and the estimated dispersion coefficient was between 0.0015 and 0.0051 cm2/sec. In terms of monitoring changes in groundwater conductivity, the ERT technique has two major advantages over monitoring wells: (1) it measures a larger area and provides more representative results; and, (2) it does not withdraw groundwater samples, and therefore does not affect the groundwater flow. The objective of this research is to measure groundwater velocity with the ERT technique using only one well. The experiments in this research were divided into two parts. The first part evaluated the accuracy and repeatability of the ERT technique using a dipole-dipole array, and the second part estimated the groundwater velocity in a sandbox using the ERT technique. The length, width, and height of the sandbox, which was made of acrylic, were 1.5, 5, and 1.0 m, respectively. The ERT sandbox was sequentially filled with 5-cm layers of the silica sand to a total height of 70 cm. A total of 32 electrodes spaced every 5-cm were installed in the center of the sandbox. Three monitoring wells were installed along the line of the electrodes. Both no-flow and constant flow (NaCl solution with electrical conductivity and concentration of 5,000 μs/cm and 2.456 g/L, respectively) tracer experiments were conducted.
Estimation of Ligand-Receptor Binding Affinity from Fluctuation of Their Interface
NASA Astrophysics Data System (ADS)
Iwamoto, Koji; Ode, Hirotaka; Ohta, Masami; Misu, Takashi; Hata, Masayuki; Neya, Saburo; Hoshino, Tyuji
2005-10-01
It is necessary for the understanding of protein interactions or in silico drug designs to accurately estimate ligand-receptor affinity. The energy calculation based on the electrostatic force, van der Waals force, and solvation effect is a direct method of computing the magnitude of the interaction between ligand and receptor. By this conventional method, however, it is difficult to estimate a slight difference in binding affinity with sufficient accuracy. We propose a novel concept for the evaluation of binding affinity between a ligand and its receptor by functionalizing the fluctuation at the ligand-receptor interface. This method enables an adequate estimation with a high accuracy compared with the conventional energetic approach. Human immunodeficiency virus type 1 (HIV-1) protease and its inhibitor are used to explain how binding affinity is extracted from the fluctuation in interfacial energy, and a combination of an antigen and its antibody is examined to demonstrate the compatibility between the estimation from the interfacial fluctuation and the experimentally measured binding energy.
Egomotion estimation with optic flow and air velocity sensors.
Rutkowski, Adam J; Miller, Mikel M; Quinn, Roger D; Willis, Mark A
2011-06-01
We develop a method that allows a flyer to estimate its own motion (egomotion), the wind velocity, ground slope, and flight height using only inputs from onboard optic flow and air velocity sensors. Our artificial algorithm demonstrates how it could be possible for flying insects to determine their absolute egomotion using their available sensors, namely their eyes and wind sensitive hairs and antennae. Although many behaviors can be performed by only knowing the direction of travel, behavioral experiments indicate that odor tracking insects are able to estimate the wind direction and control their absolute egomotion (i.e., groundspeed). The egomotion estimation method that we have developed, which we call the opto-aeronautic algorithm, is tested in a variety of wind and ground slope conditions using a video recorded flight of a moth tracking a pheromone plume. Over all test cases that we examined, the algorithm achieved a mean absolute error in height of 7% or less. Furthermore, our algorithm is suitable for the navigation of aerial vehicles in environments where signals from the Global Positioning System are unavailable.
Pan, Xiaochang; Liu, Ke; Shao, Jinghua; Gao, Jing; Huang, Lingyun; Bai, Jing; Luo, Jianwen
2015-11-01
Tissue motion estimation is widely used in many ultrasound techniques. Rigid-model-based and nonrigid-modelbased methods are two main groups of space-domain methods of tissue motion estimation. The affine model is one of the commonly used nonrigid models. The performances of the rigid model and affine model have not been compared on ultrasound RF signals, which have been demonstrated to obtain higher accuracy, precision, and resolution in motion estimation compared with B-mode images. In this study, three methods, i.e., the normalized cross-correlation method with rigid model (NCC), the optical flow method with rigid model (OFRM), and the optical flow method with affine model (OFAM), are compared using ultrasound RF signals, rather than the B-mode images used in previous studies. Simulations, phantom, and in vivo experiments are conducted to make the comparison. In the simulations, the root-mean-square errors (RMSEs) of axial and lateral displacements and strains are used to assess the accuracy of motion estimation, and the elastographic signal-tonoise ratio (SNRe) and contrast-to-noise ratio (CNRe) are used to evaluate the quality of axial strain images. In the phantom experiments, the registration error between the pre- and postdeformation RF signals, as well as the SNRe and CNRe of axial strain images, are utilized as the evaluation criteria. In the in vivo experiments, the registration error is used to evaluate the estimation performance. The results show that the affinemodel- based method (i.e., OFAM) obtains the lowest RMSE or registration error and the highest SNRe and CNRe among all the methods. The affine model is demonstrated to be superior to the rigid model in motion estimation based on RF signals.
Man-made velocity estimators based on insect vision
NASA Astrophysics Data System (ADS)
Rajesh, Sreeja; O'Carroll, David; Abbott, Derek
2005-04-01
reliability and robustness of velocity estimation.
Estimation of unsteady aerodynamic forces using pointwise velocity data
NASA Astrophysics Data System (ADS)
Gómez, F.; Sharma, A. S.; Blackburn, H. M.
2016-10-01
A novel method to estimate unsteady aerodynamic force coefficients from pointwise velocity measurements is presented. The methodology is based on a resolvent-based reduced-order model which requires the mean flow to obtain physical flow structures and pointwise measurement to calibrate their amplitudes. A computationally-affordable time-stepping methodology to obtain resolvent modes in non-trivial flow domains is introduced and compared to previous existing matrix-free and matrix-forming strategies. The technique is applied to the unsteady flow around an inclined square cylinder at low Reynolds number. The potential of the methodology is demonstrated through good agreement between the fluctuating pressure distribution on the cylinder and the temporal evolution of the unsteady lift and drag coefficients predicted by the model and those computed by direct numerical simulation.
Shyu, Conrad; Cavileer, Timothy D.; Nagler, James J.; Ytreberg, F. Marty
2011-02-01
Environmental estrogens have been the subject of intense research due to their documented detrimental effects on the health of fish and wildlife and their potential to negatively impact humans. A complete understanding of how these compounds affect health is complicated because environmental estrogens are a structurally heterogeneous group of compounds. In this work, computational molecular dynamics simulations were utilized to predict the binding affinity of different compounds using rainbow trout (Oncorhynchus mykiss) estrogen receptors (ERs) as a model. Specifically, this study presents a comparison of the binding affinity of the natural ligand estradiol-17{beta} to the four rainbow trout ER isoforms with that of three known environmental estrogens 17{alpha}-ethinylestradiol, bisphenol A, and raloxifene. Two additional compounds, atrazine and testosterone, that are known to be very weak or non-binders to ERs were tested. The binding affinity of these compounds to the human ER{alpha} subtype is also included for comparison. The results of this study suggest that, when compared to estradiol-17{beta}, bisphenol A binds less strongly to all four receptors, 17{alpha}-ethinylestradiol binds more strongly, and raloxifene has a high affinity for the {alpha} subtype only. The results also show that atrazine and testosterone are weak or non-binders to the ERs. All of the results are in excellent qualitative agreement with the known in vivo estrogenicity of these compounds in the rainbow trout and other fishes. Computational estimation of binding affinities could be a valuable tool for predicting the impact of environmental estrogens in fish and other animals.
DEPOSITION VELOCITY ESTIMATION WITH THE GENII V2 SOFTWARE
Hutchins, H.
2012-04-23
In 2010, the Department of Energy (DOE) Chief of Nuclear Safety and Office of Health, Safety and Security (HSS), with the support of industry experts in atmospheric sciences and accident dose consequences analysis, performed detailed analyses of the basis for the dry deposition velocity (DV) values used in the MACCS2 computer code. As a result of these analyses, DOE concluded that the historically used default DV values of 1 centimeter/second (cm/s) for unfiltered/unmitigated releases and 0.1 cm/s for filtered/mitigated releases may not be reasonably conservative for all DOE sites and accident scenarios. HSS recently issued Safety Bulletin 2011-02, Accident Analysis Parameter Update, recommending the use of the newly developed default DV, 0.1 cm/s for an unmitigated/unfiltered release. Alternatively site specific DV values can be developed using GENII version 2 (GENII v2) computer code. Key input parameters for calculating DV values include surface roughness, maximum wind speed for calm, particle size, particle density and meteorological data (wind speed and stability class). This paper will include reasonably conservative inputs, and a truncated parametric study. In lieu of the highly-conservative recommended DV value (0.1cm/s) for unmitigated/unfiltered release, GENII v2 has been used to justify estimated 95th percentile DV values. Also presented here are atmospheric dilution factors ({chi}/Q values) calculated with the MACCS2 code using the DV values form GENII v2, {chi}/Q values calculated directly with GENII v2, and a discussion of these results compare with one another. This paper will give an overview of the process of calculating DV with GENII v2 including a discussion of the sensitivity of input parameters.
Estimation of velocity perturbations in satellite fragmentation events
NASA Technical Reports Server (NTRS)
Tan, Arjun
1989-01-01
The magnitude, variance and directionality of the velocity perturbations of the fragments of a satellite can shed valuable information regarding the nature and intensity of the fragmentation. Up until now, the only method used to calculate the three orthogonal components of the velocity change consisted of inverting the process of evaluating the changes in the orbital elements of the fragments due to velocity perturbing forces. But the traditional method failed in five different cases: (1) when the parent satellite's orbit was circular; (2) and (3) when the true anomaly of the parent was either 0 deg or 180 deg; and (4) and (5) when the argument of latitude of the parent was 90 deg or 270 deg. Described here is a new method of calculating the velocity perturbations which is free from the shortcomings of the traditional method and could be used in all occasions, provided the fragmentation data and the orbital elements data are consistent with one another.
Radiocarbon Determinations for Estimating Groundwater Flow Velocities in Central Florida.
Hanshaw, B B; Back, W; Rubin, M
1965-04-23
Carbon-14 activity was determined from HCO(3)(-) in samples of groundwater obtained from the principal artesian aquifer in Florida. From these data the "age" of water obtained from a series of wells, each progressively farther down gradient on the piezometric surface, was established. Relative carbon-14 ages indicated a velocity of groundwater movement of 23 feet (7 meters) per year for about 85 miles (137 kilometers) of travel. A velocity of 23 feet per year was calculated independently from Darcy's law.
Radiocarbon determinations for estimating groundwater flow velocities in central Florida
Hanshaw, B.B.; Back, W.; Rubin, M.
1965-01-01
Carbon-14 activity was determined from HCO3- in samples of groundwater obtained from the principal artesian aquifer in Florida. From these data the "age" of water obtained from a series of wells, each progressively farther down gradient on the piezometric surface, was established. Relative carbon-14 ages indicated a velocity of groundwater movement of 23 feet (7 meters) per year for about 85 miles (137 kilometers) of travel. A velocity of 23 feet per year was calculated independently from Darcy's law.
Hurst exponent estimation of self-affine time series using quantile graphs
NASA Astrophysics Data System (ADS)
Campanharo, Andriana S. L. O.; Ramos, Fernando M.
2016-02-01
In the context of dynamical systems, time series analysis is frequently used to identify the underlying nature of a phenomenon of interest from a sequence of observations. For signals with a self-affine structure, like fractional Brownian motions (fBm), the Hurst exponent H is one of the key parameters. Here, the use of quantile graphs (QGs) for the estimation of H is proposed. A QG is generated by mapping the quantiles of a time series into nodes of a graph. H is then computed directly as the power-law scaling exponent of the mean jump length performed by a random walker on the QG, for different time differences between the time series data points. The QG method for estimating the Hurst exponent was applied to fBm with different H values. Comparison with the exact H values used to generate the motions showed an excellent agreement. For a given time series length, estimation error depends basically on the statistical framework used for determining the exponent of the power-law model. The QG method is numerically simple and has only one free parameter, Q, the number of quantiles/nodes. With a simple modification, it can be extended to the analysis of fractional Gaussian noises.
Estimation of Laminar Burning Velocities by Direct Digital Photography
ERIC Educational Resources Information Center
Uske, J.; Barat, R.
2004-01-01
The Bunsen burner flame, which is the most common flame in the laboratory, can be easily studied for its dynamics because of modern, economical digital technology available to student laboratories. Direct digital photography of Bunsen flames is used to obtain laminar burning velocities of selected gaseous hydrocarbon/air flames.
Estimating Radar Velocity using Direction of Arrival Measurements
Doerry, Armin Walter; Horndt, Volker; Bickel, Douglas Lloyd; Naething, Richard M.
2014-09-01
Direction of Arrival (DOA) measurements, as with a monopulse antenna, can be compared against Doppler measurements in a Synthetic Aperture Radar ( SAR ) image to determine an aircraft's forward velocity as well as its crab angle, to assist the aircraft's navigation as well as improving high - performance SAR image formation and spatial calibration.
Can the curriculum be used to estimate critical velocity in young competitive swimmers?
Costa, Aldo M; Silva, António J; Louro, Hugo; Reis, Victor M; Garrido, Nuno D; Marques, Mário C; Marinho, Daniel A
2009-01-01
The aims of the present study were to assess critical velocity using the swimmer curriculum in front crawl events and to compare critical velocity to the velocity corresponding to a 4 mmol·l(-1) of blood lactate concentration and to the velocity of a 30 min test. The sample included 24 high level male swimmers ranged between 14 and 16 years old. For each subject the critical velocity, the velocity corresponding to a 4 mmol·l(-1) of blood lactate concentration and the mean velocity of a 30 min test were determined. The critical velocity was also estimated by considering the best performance of a swimmer over several distances based on the swimmer curriculum. Critical velocity including 100, 200 and 400 m events was not different from the velocity of 4 mmol·l(-1) of blood lactate concentration. Critical velocity including all the swimmer events was not different from the velocity of a 30 min test. The assessment of critical velocity based upon the swimmer curriculum would therefore seem to be a good approach to determine the aerobic ability of a swimmer. The selection of the events to be included in critical velocity assessment must be a main concern in the evaluation of the swimmer. Key pointsCritical velocity using 100, 200 and 400 m events was not different from the velocity of 4 mmol·l(-1) of blood lactate concentration.Critical velocity using all the swimmer events was not different from the velocity of a 30 min test.The assessment of critical velocity based upon the swimmer curriculum seemed to be a good approach to determine the aerobic capacity of a swimmer.The decision on the events to be analysed must be a main concern in the evaluation of the swimmer critical velocity.
Coda wave interferometry for estimating nonlinear behavior in seismic velocity.
Snieder, Roel; Grêt, Alexandre; Douma, Huub; Scales, John
2002-03-22
In coda wave interferometry, one records multiply scattered waves at a limited number of receivers to infer changes in the medium over time. With this technique, we have determined the nonlinear dependence of the seismic velocity in granite on temperature and the associated acoustic emissions. This technique can be used in warning mode, to detect the presence of temporal changes in the medium, or in diagnostic mode, where the temporal change in the medium is quantified.
Robust angle-independent blood velocity estimation based on dual-angle plane wave imaging.
Fadnes, Solveig; Ekroll, Ingvild Kinn; Nyrnes, Siri Ann; Torp, Hans; Lovstakken, Lasse
2015-10-01
Two-dimensional blood velocity estimation has shown potential to solve the angle-dependency of conventional ultrasound flow imaging. Clutter filtering, however, remains a major challenge for large beam-to-flow angles, leading to signal drop-outs and corrupted velocity estimates. This work presents and evaluates a compounding speckle tracking (ST) algorithm to obtain robust angle-independent 2-D blood velocity estimates for all beam-to-flow angles. A dual-angle plane wave imaging setup with full parallel receive beamforming is utilized to achieve high-frame-rate speckle tracking estimates from two scan angles, which may be compounded to obtain velocity estimates of increased robustness. The acquisition also allows direct comparison with vector Doppler (VD) imaging. Absolute velocity bias and root-mean-square (RMS) error of the compounding ST estimations were investigated using simulations of a rotating flow phantom with low velocities ranging from 0 to 20 cm/s. In a challenging region where the estimates were influenced by clutter filtering, the bias and RMS error for the compounding ST estimates were 11% and 2 cm/s, a significant reduction compared with conventional single-angle ST (22% and 4 cm/s) and VD (36% and 6 cm/s). The method was also tested in vivo for vascular and neonatal cardiac imaging. In a carotid artery bifurcation, the obtained blood velocity estimates showed that the compounded ST method was less influenced by clutter filtering than conventional ST and VD methods. In the cardiac case, it was observed that ST velocity estimation is more affected by low signal-to-noise (SNR) than VD. However, with sufficient SNR the in vivo results indicated that a more robust angle-independent blood velocity estimator is obtained using compounded speckle tracking compared with conventional ST and VD methods. PMID:26470038
Robust angle-independent blood velocity estimation based on dual-angle plane wave imaging.
Fadnes, Solveig; Ekroll, Ingvild Kinn; Nyrnes, Siri Ann; Torp, Hans; Lovstakken, Lasse
2015-10-01
Two-dimensional blood velocity estimation has shown potential to solve the angle-dependency of conventional ultrasound flow imaging. Clutter filtering, however, remains a major challenge for large beam-to-flow angles, leading to signal drop-outs and corrupted velocity estimates. This work presents and evaluates a compounding speckle tracking (ST) algorithm to obtain robust angle-independent 2-D blood velocity estimates for all beam-to-flow angles. A dual-angle plane wave imaging setup with full parallel receive beamforming is utilized to achieve high-frame-rate speckle tracking estimates from two scan angles, which may be compounded to obtain velocity estimates of increased robustness. The acquisition also allows direct comparison with vector Doppler (VD) imaging. Absolute velocity bias and root-mean-square (RMS) error of the compounding ST estimations were investigated using simulations of a rotating flow phantom with low velocities ranging from 0 to 20 cm/s. In a challenging region where the estimates were influenced by clutter filtering, the bias and RMS error for the compounding ST estimates were 11% and 2 cm/s, a significant reduction compared with conventional single-angle ST (22% and 4 cm/s) and VD (36% and 6 cm/s). The method was also tested in vivo for vascular and neonatal cardiac imaging. In a carotid artery bifurcation, the obtained blood velocity estimates showed that the compounded ST method was less influenced by clutter filtering than conventional ST and VD methods. In the cardiac case, it was observed that ST velocity estimation is more affected by low signal-to-noise (SNR) than VD. However, with sufficient SNR the in vivo results indicated that a more robust angle-independent blood velocity estimator is obtained using compounded speckle tracking compared with conventional ST and VD methods.
Ofuchi, César Yutaka; Coutinho, Fabio Rizental; Neves, Flávio; de Arruda, Lucia Valéria Ramos; Morales, Rigoberto Eleazar Melgarejo
2016-01-01
In this paper the extended autocorrelation velocity estimator is evaluated and compared using a nondestructive ultrasonic device. For this purpose, three velocity estimators are evaluated and compared. The autocorrelation method (ACM) is the most used and well established in current ultrasonic velocity profiler technology, however, the technique suffers with phase aliasing (also known as the Nyquist limit) at higher velocities. The cross-correlation method (CCM) is also well known and does not suffer with phase aliasing as it relies on time shift measurements between emissions. The problem of this method is the large computational burden due to several required mathematical operations. Recently, an extended autocorrelation method (EAM) which combines both ACM and CCM was developed. The technique is not well known within the fluid engineering community, but it can measure velocities beyond the Nyquist limit without the ACM phase aliasing issues and with a lower computational cost than CCM. In this work, all three velocity estimation methods are used to measure a uniform flow of the liquid inside a controlled rotating cylinder. The root-mean-square deviation variation coefficient (CVRMSD) of the velocity estimate and the reference cylinder velocity was used to evaluate the three different methods. Results show that EAM correctly measures velocities below the Nyquist limit with less than 2% CVRMSD. Velocities beyond the Nyquist limit are only measured well by EAM and CCM, with the advantage of the former of being computationally 15 times faster. Furthermore, the maximum value of measurable velocity is also investigated considering the number of times the velocity surpasses the Nyquist limit. The combination of number of pulses and number of samples, which highly affects the results, are also studied in this work. Velocities up to six times the Nyquist limit could be measurable with CCM and EAM using a set of parameters as suggested in this work. The results validate
Ofuchi, César Yutaka; Coutinho, Fabio Rizental; Neves, Flávio; de Arruda, Lucia Valéria Ramos; Morales, Rigoberto Eleazar Melgarejo
2016-01-01
In this paper the extended autocorrelation velocity estimator is evaluated and compared using a nondestructive ultrasonic device. For this purpose, three velocity estimators are evaluated and compared. The autocorrelation method (ACM) is the most used and well established in current ultrasonic velocity profiler technology, however, the technique suffers with phase aliasing (also known as the Nyquist limit) at higher velocities. The cross-correlation method (CCM) is also well known and does not suffer with phase aliasing as it relies on time shift measurements between emissions. The problem of this method is the large computational burden due to several required mathematical operations. Recently, an extended autocorrelation method (EAM) which combines both ACM and CCM was developed. The technique is not well known within the fluid engineering community, but it can measure velocities beyond the Nyquist limit without the ACM phase aliasing issues and with a lower computational cost than CCM. In this work, all three velocity estimation methods are used to measure a uniform flow of the liquid inside a controlled rotating cylinder. The root-mean-square deviation variation coefficient (CVRMSD) of the velocity estimate and the reference cylinder velocity was used to evaluate the three different methods. Results show that EAM correctly measures velocities below the Nyquist limit with less than 2% CVRMSD. Velocities beyond the Nyquist limit are only measured well by EAM and CCM, with the advantage of the former of being computationally 15 times faster. Furthermore, the maximum value of measurable velocity is also investigated considering the number of times the velocity surpasses the Nyquist limit. The combination of number of pulses and number of samples, which highly affects the results, are also studied in this work. Velocities up to six times the Nyquist limit could be measurable with CCM and EAM using a set of parameters as suggested in this work. The results validate
Ofuchi, César Yutaka; Coutinho, Fabio Rizental; Neves, Flávio; de Arruda, Lucia Valéria Ramos; Morales, Rigoberto Eleazar Melgarejo
2016-08-09
In this paper the extended autocorrelation velocity estimator is evaluated and compared using a nondestructive ultrasonic device. For this purpose, three velocity estimators are evaluated and compared. The autocorrelation method (ACM) is the most used and well established in current ultrasonic velocity profiler technology, however, the technique suffers with phase aliasing (also known as the Nyquist limit) at higher velocities. The cross-correlation method (CCM) is also well known and does not suffer with phase aliasing as it relies on time shift measurements between emissions. The problem of this method is the large computational burden due to several required mathematical operations. Recently, an extended autocorrelation method (EAM) which combines both ACM and CCM was developed. The technique is not well known within the fluid engineering community, but it can measure velocities beyond the Nyquist limit without the ACM phase aliasing issues and with a lower computational cost than CCM. In this work, all three velocity estimation methods are used to measure a uniform flow of the liquid inside a controlled rotating cylinder. The root-mean-square deviation variation coefficient (CVRMSD) of the velocity estimate and the reference cylinder velocity was used to evaluate the three different methods. Results show that EAM correctly measures velocities below the Nyquist limit with less than 2% CVRMSD. Velocities beyond the Nyquist limit are only measured well by EAM and CCM, with the advantage of the former of being computationally 15 times faster. Furthermore, the maximum value of measurable velocity is also investigated considering the number of times the velocity surpasses the Nyquist limit. The combination of number of pulses and number of samples, which highly affects the results, are also studied in this work. Velocities up to six times the Nyquist limit could be measurable with CCM and EAM using a set of parameters as suggested in this work. The results validate
Impact of Seasonal Changes on Noise and Velocity Estimation
NASA Astrophysics Data System (ADS)
Klos, Anna; Bogusz, Janusz
2016-04-01
Each of the GPS-derived time series consists of the deterministic and stochastic part. We propose that the deterministic part includes all harmonics of periodicities from 1st to 9th of residual Chandler, tropical and draconitic periods and compare it with commonly used calculations of the annual and semi-annual tropical curve. Then, we address the issues of whether all residual periodicities, as proposed here, need to be taken into consideration when performing noise analysis. We use the position time series from 180 International GNSS Service stations obtained at the Jet Propulsion Laboratory using the GIPSY-OASIS software in a Precise Point Positioning mode. The longest series has 22.1 years of GPS daily solutions. The spectral indices range from -0.12 to -0.92, while the median values of „global" spectral indices are equal to: -0.41 ± 0.15, -0.38 ± 0.12 and -0.33 ± 0.18 for North, East and Up components, respectively. All non-modelled geophysical processes or non-included artificial effects in time series lead to an underestimation of errors of velocities, but also to changes in the velocity values themselves. The proposed assumption of seasonal oscillations subtraction caused the Akaike information criterion values to show a decrease in the median value of 30 %, which in fact means that all the seasonals mentioned here must be taken into account when analyzing noises. Finally, we noticed that there are some of the GPS stations that improved their velocity uncertainty even of 56 %.
In vitro verification of multiple-receiver Doppler ultrasound for velocity estimation improvement.
Hallac, Rami R; Agarwal, Mangilal; Jones, Steven A
2010-06-01
The coherent scattering effect, which introduces noise in Doppler-derived velocity estimates, is caused by constructive and destructive interference of sound waves scattered from multiple particles. Because the phase relationship between signals scattered from different particles depends on the orientation of the receiver, the error in a given velocity estimate depends on the receiver location. To examine this dependence, the velocity of a steady uniform flow was measured simultaneously with a transceiver and three receivers, and the cross-correlation coefficients between velocity estimates for pairs of crystals were calculated. The velocity estimates were nearly independent, with cross-correlation coefficients of approximately 0.2. This result agrees with our previously published numerical simulation studies which demonstrated that the coherent scattering noise in receivers separated by 5 degrees or more was nearly uncorrelated. Consequently, the contribution of coherent scattering noise can be reduced by averaging out noise in signals obtained from multiple receivers.
Estimation of circumferential fiber shortening velocity by echocardiography.
Ruschhaupt, D G; Sodt, P C; Hutcheon, N A; Arcilla, R A
1983-07-01
The M-mode and two-dimensional echocardiograms of 40 young patients were analyzed to compare the mean circumferential fiber shortening velocity (Vcf) of the left ventricle calculated separately by two methods. The mean circumferential fiber shortening velocity was derived from the M-mode echocardiogram as minor axis shortening/ejection time and derived from the two-dimensional echocardiogram as actual circumference change/ejection time. With computer assistance, circumference was determined from the short-axis two-dimensional echocardiographic images during end-diastole and end-systole. Good correlations were obtained between the left ventricular diameter derived by M-mode echocardiography and the vertical axis during end-diastole (r = 0.79) and end-systole (r = 0.88) derived by two-dimensional echocardiography. Likewise, high correlations were noted between diameter and circumference in end-diastole (r = 0.89) and end-systole (r = 0.88). However, comparison of Vcf obtained by M-mode echocardiography with that obtained by two-dimensional echocardiography showed only fair correlation (r = 0.68). Moreover, the diameter/circumference ratio determined in end-diastole and end-systole differed significantly (p less than 0.001), possibly owing to the change in geometry of the ventricular sector image during systole. Although Vcf derived by M-mode echocardiography is a useful index of left ventricular performance, it does not truly reflect the circumference change during systole.
Velocity estimation of slow moving targets in AT-InSAR systems
NASA Astrophysics Data System (ADS)
Budillon, A.; Pascazio, V.; Schirinzi, G.
2007-10-01
Along Track Interferometric Synthetic Aperture Radar (AT-InSAR) systems use more than one SAR antennas (typically two), mounted on the same platform and displaced along the platform moving direction, to detect slow ground moving targets. The phase of the ATI signal is related to the target motion parameters and may thus be used to estimate the radial velocity. In this paper we approach the velocity estimation problem using statistical techniques based on the statistical distribution of the measured interferometric phases. We analyze the radial velocity estimation with respect to ATI system parameters, such as velocity values, the signal to clutter ratio (SCR), the clutter to noise ratio (CNR), considering a deterministic target whose velocity is estimated using a Gaussian model. This model allows to take into account the lack of knowledge of the target radar cross section (RCS) values and provides an analytical form for the interferometric phase probability density function. Simulations results show that the adoption of Maximum Likelihood (ML) techniques, to perform a joint estimation of velocity and SCR, and multi-channel configurations, to overcome ambiguities problems, provide very good velocity estimation accuracy.
Multiple GPCR conformations and signalling pathways: implications for antagonist affinity estimates
Baker, Jillian G.; Hill, Stephen J.
2007-01-01
Antagonist affinity measurements have traditionally been considered important in characterizing the cell-surface receptors present in a particular cell or tissue. A central assumption has been that antagonist affinity is constant for a given receptor–antagonist interaction, regardless of the agonist used to stimulate that receptor or the downstream response that is measured. As a consequence, changes in antagonist affinity values have been taken as initial evidence for the presence of novel receptor subtypes. Emerging evidence suggests, however, that receptors can possess multiple binding sites and the same receptor can show different antagonist affinity measurements under distinct experimental conditions. Here, we discuss several mechanisms by which antagonists have different affinities for the same receptor as a consequence of allosterism, coupling to different G proteins, multiple (but non-interacting) receptor sites, and signal-pathway-dependent pharmacology (where the pharmacology observed varies depending on the signalling pathway measured). PMID:17629959
Estimating phosphorus concentrations following alum treatment using apparent settling velocity
Panuska, John; Robertson, Dale M.
2009-01-01
he apparent settling velocity (Vs) is a term used in empirical, steady-state, mass-balance lake models to represent the net phosphorus flux from the water column. The Vollenweider (1969) mixed-reactor lake model was rearranged and used to calculate Vs values for total phosphorus (TP) for three lakes treated with alum to reduce the internal flux of P to the water column (Delavan Lake, Wisconsin; Lake Morey, Vermont; and West Twin Lake, Ohio). An analysis of Vs values was conducted using data from these three lakes for both the pre- and post-alum treated conditions. Analysis of Vs values for both the pre- and post-alum conditions in Lake Morey and West Twin Lake resulted in a post-treatment mean Vs value of 7 ± 2.0 m·yr−1. The effect of the alum treatment, although short-lived in Delavan Lake, resulted in a mean post-treatment Vs value of 3.4 ± 0.3 m·yr−1. The consistency in the post-treatment Vs values in Lake Morey and West Twin Lake is used to demonstrate a predictive analysis method for water column TP concentrations in lakes following a successful treatment of the anoxic sediment area with alum. Additional pre- and post-alum in-lake and watershed loading data are needed to advance this concept into a management model.
Lygeros, A.I.; Magoulas, K.G.
1986-12-01
Here is a way to estimate maximum allowable vapor velocity and entrainment in a distillation column. The method can easily be computerized. It is based on equations derived from the widely accepted correlations. The equation for flooding velocity is applicable to bubble-cup, sieve and valve trays, while the entrainment equation applies only to sieve trays.
NASA Astrophysics Data System (ADS)
Pedersen, Mads Møller; Pihl, Michael Johannes; Haugaard, Per; Hansen, Jens Munk; Lindskov Hansen, Kristoffer; Bachmann Nielsen, Michael; Jensen, Jørgen Arendt
2011-03-01
Spectral velocity estimation is considered the gold standard in medical ultrasound. Peak systole (PS), end diastole (ED), and resistive index (RI) are used clinically. Angle correction is performed using a flow angle set manually. With Transverse Oscillation (TO) velocity estimates the flow angle, peak systole (PSTO), end diastole (EDTO), and resistive index (RITO) are estimated. This study investigates if these clinical parameters are estimated equally good using spectral and TO data. The right common carotid arteries of three healthy volunteers were scanned longitudinally. Average TO flow angles and std were calculated { 52+/-18 ; 55+/-23 ; 60+/-16 }°. Spectral angles { 52 ; 56 ; 52 }° were obtained from the B-mode images. Obtained values are: PSTO { 76+/-15 ; 89+/-28 ; 77+/-7 } cm/s, spectral PS { 77 ; 110 ; 76 } cm/s, EDTO { 10+/-3 ; 14+/-8 ; 15+/-3 } cm/s, spectral ED { 18 ; 13 ; 20 } cm/s, RITO { 0.87+/-0.05 ; 0.79+/-0.21 ; 0.79+/-0.06 }, and spectral RI { 0.77 ; 0.88 ; 0.73 }. Vector angles are within +/-two std of the spectral angle. TO velocity estimates are within +/-three std of the spectral estimates. RITO are within +/-two std of the spectral estimates. Preliminary data indicates that the TO and spectral velocity estimates are equally good. With TO there is no manual angle setting and no flow angle limitation. TO velocity estimation can also automatically handle situations where the angle varies over the cardiac cycle. More detailed temporal and spatial vector estimates with diagnostic potential are available with the TO velocity estimation.
The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities
Genheden, Samuel; Ryde, Ulf
2015-01-01
Introduction: The molecular mechanics energies combined with the Poisson–Boltzmann or generalized Born and surface area continuum solvation (MM/PBSA and MM/GBSA) methods are popular approaches to estimate the free energy of the binding of small ligands to biological macromolecules. They are typically based on molecular dynamics simulations of the receptor–ligand complex and are therefore intermediate in both accuracy and computational effort between empirical scoring and strict alchemical perturbation methods. They have been applied to a large number of systems with varying success. Areas covered: The authors review the use of MM/PBSA and MM/GBSA methods to calculate ligand-binding affinities, with an emphasis on calibration, testing and validation, as well as attempts to improve the methods, rather than on specific applications. Expert opinion: MM/PBSA and MM/GBSA are attractive approaches owing to their modular nature and that they do not require calculations on a training set. They have been used successfully to reproduce and rationalize experimental findings and to improve the results of virtual screening and docking. However, they contain several crude and questionable approximations, for example, the lack of conformational entropy and information about the number and free energy of water molecules in the binding site. Moreover, there are many variants of the method and their performance varies strongly with the tested system. Likewise, most attempts to ameliorate the methods with more accurate approaches, for example, quantum-mechanical calculations, polarizable force fields or improved solvation have deteriorated the results. PMID:25835573
NASA Astrophysics Data System (ADS)
Hamada, Atsushi; Takayabu, Yukari N.
2016-05-01
We demonstrate that the rate of development of cumulus clouds, as inferred from the so-called geostationary satellite "rapid-scan" measurements, is a good proxy for convective cloud top vertical velocity related to deep convective clouds. Convective cloud top vertical velocity is estimated from the decreasing rate of infrared brightness temperature observed by the Multi-functional Transport SATellite-1R (MTSAT-1R) over the ocean south of Japan during boreal summer. The frequency distribution of the estimated convective cloud top vertical velocity at each height is shown to distribute lognormally, and it is consistent with the statistical characteristics of direct measurements acquired in previous studies.
Della Ducata, Daniela; Jaehrling, Jan; Hänel, Cornelia; Satzger, Marion; Wolber, Meike; Ostendorp, Ralf; Pabst, Stefan; Brocks, Bodo
2015-12-01
The generation of therapeutic antibodies with extremely high affinities down to the low picomolar range is today feasible with state-of-the art recombinant technologies. However, reliable and efficient identification of lead candidates with the desired affinity from a pool of thousands of antibody clones remains a challenge. Here, we describe a high-throughput procedure that allows reliable affinity screening of unpurified immunoglobulin G or antibody fragments. The method is based on the principle of solution equilibrium titration (SET) using highly sensitive electrochemiluminescence as a readout system. Because the binding partners are not labeled, the resulting KD represents a sound approximation of the real affinity. For screening, diluted bacterial lysates or cell culture supernatants are equilibrated with four different concentrations of a soluble target molecule, and unbound antibodies are subsequently quantified on 384-well Meso Scale Discovery (MSD) plates coated with the respective antigen. For determination of KD values from the resulting titration curves, fit models deduced from the law of mass action for 1:1 and 2:1 binding modes are applied to assess hundreds of interactions simultaneously. The accuracy of the method is demonstrated by comparing results from different screening campaigns from affinity optimization projects with results from detailed affinity characterization.
A VLBI baseline post-adjustment approach for station velocity estimation in Eurasian continent
NASA Astrophysics Data System (ADS)
Zhang, Zhibin; Liu, Xiang
2014-10-01
Baseline lengths and their time-derivatives among 58 geodetic VLBI stations were fitted by using 4439 observing sessions from the International VLBI Service for Geodesy and Astrometry (IVS). First, the velocities of eight stations in Eurasian continent were set as unknown quantities. Then, two standard global solutions from 3523 IVS sessions and 1110 sessions from database code XA, respectively, were applied prior to all-station coordinates and the non-estimated station velocities. Finally, from the relations among the coordinates, velocities, baseline length and its time-derivative, two types of baseline post-adjustment (BPA) were used to estimate the velocities of the eight stations. We discuss the data processing details, including the effect of different prior values for the stations and the optimal solution. The results suggest that the precision of the station velocities based on the proposed approach is comparable to that of the global solution of the XA sessions. The baseline structure and the prior values of the stations affect the velocity estimates. Compared to the standard method of velocity estimation, there are no external constrains and conditions used in the proposed method.
An estimation technique of Rayleigh wave phase velocities using arrays with arbitrary geometry
NASA Astrophysics Data System (ADS)
Shiraishi, H.; Asanuma, H.
2008-12-01
The mictotremor survey method (MSM) is one of the most practical techniques to estimate velocity structure of shear waves in sedimentary layers. In the MSM, the velocity models are determined by inversion analysis of the Rayleigh wave phase velocity dispersion curve observed from microtremors. In most of the cases, the phase velocity dispersion curve is obtained by either the spatial autocorrelation (SPAC) technique or the frequency-wavenumber (F-K) technique applied to array measurements of microtremors. These techniques place significant restrictions on the array geometry and number of stations required, which limits the applicability of MSM, especially in urban areas. We have derived a new technique for estimating phase velocities of Rayleigh waves. This new technique (the direct estimation method: DEM) enables to the use of flexible array configurations and a minimal number of stations. Moreover, the DEM can be applied to records from existing station arrays, such as those in an earthquake monitoring network. In the DEM, microtremors detected by arrays with arbitrary geometry can be represented by complex coherence functions (CCFs: Shiraishi et. al. 2006) of the Rayleigh wave. The CCF is derived from analytic solution of Lamb's problem, and it consists of the Bessel function of the first kind J0(ωr/c) (ω: angular frequency, r: distance between the stations, c: phase velocity), which is well-known function and is used in the SPAC technique to estimate phase velocity. The phase velocities can be estimated by solving the equations with the least squares approach to minimize the residual error between the observed and the theoretical values. A field experiment has been carried out to verify the effectiveness of the DEM, and the phase velocities obtained by the DEM with an array of arbitrary geometry are in excellent agreement with those obtained using the SPAC technique.
Capoferri, Luigi; Verkade-Vreeker, Marlies C. A.; Buitenhuis, Danny; Commandeur, Jan N. M.; Pastor, Manuel; Vermeulen, Nico P. E.; Geerke, Daan P.
2015-01-01
Prediction of human Cytochrome P450 (CYP) binding affinities of small ligands, i.e., substrates and inhibitors, represents an important task for predicting drug-drug interactions. A quantitative assessment of the ligand binding affinity towards different CYPs can provide an estimate of inhibitory activity or an indication of isoforms prone to interact with the substrate of inhibitors. However, the accuracy of global quantitative models for CYP substrate binding or inhibition based on traditional molecular descriptors can be limited, because of the lack of information on the structure and flexibility of the catalytic site of CYPs. Here we describe the application of a method that combines protein-ligand docking, Molecular Dynamics (MD) simulations and Linear Interaction Energy (LIE) theory, to allow for quantitative CYP affinity prediction. Using this combined approach, a LIE model for human CYP 1A2 was developed and evaluated, based on a structurally diverse dataset for which the estimated experimental uncertainty was 3.3 kJ mol-1. For the computed CYP 1A2 binding affinities, the model showed a root mean square error (RMSE) of 4.1 kJ mol-1 and a standard error in prediction (SDEP) in cross-validation of 4.3 kJ mol-1. A novel approach that includes information on both structural ligand description and protein-ligand interaction was developed for estimating the reliability of predictions, and was able to identify compounds from an external test set with a SDEP for the predicted affinities of 4.6 kJ mol-1 (corresponding to 0.8 pKi units). PMID:26551865
Monte Carlo simulations for deriving the precision in GPR velocity estimates
NASA Astrophysics Data System (ADS)
Clark, R. A.; Booth, A.; Murray, T.
2010-12-01
Models of ground penetrating radar (GPR) propagation velocity are often used to quantify physical subsurface properties (e.g., layer thickness, porosity, water content). A common approach is to conduct semblance analysis on common midpoint (CMP) gathers, in which successive pairs of stacking velocity and travel-time are input to Dix’s Equation, to obtain a velocity estimate, termed interval stacking velocity. However, the precision in interval stacking velocity is seldom reported since it is cumbersome to obtain an analytic expression for precision particularly since Dix’s Equation has four independently resolved degrees of freedom. We present Monte Carlo simulations as a means of expressing interval stacking velocities, and its derivative quantities, as a probability density functions (PDFs). These are built using Gaussian distributions of pseudo-random samples from within the 50% contour around successive coherence responses; precision is summarised using the median and inter-quartile range of each PDF. To verify this method’s accuracy, we simulate CMP data in which travel-times are computed for reflections from two horizontal horizons at depths of 5 and 10 m, with isotropic interval velocity of 0.1 m/ns, for source-receiver offsets from 0 to 30 m. The Monte Carlo simulation produces 107 manifestations of interval stacking velocity and layer thickness, and yields estimates of 0.1±0.003 m/ns and 4.99±0.16 m, respectively. The simulation is repeated for real CMP data, acquired with 50 MHz antennas, for establishing the precision in interval stacking velocity and speculative estimates (in the absence of extensive borehole logs) of layer thickness and fractional porosity (via the complex refractive index method, CRIM). The site comprises Quaternary sediment, in which the water table is observed at ~2 m depth, overlying Cambrian basement at 10-15 m depth. The resolution of stacking velocity in semblance analysis decreases with depth, as reflected in PDFs of
Using eddy covariance to estimate air-sea gas transfer velocity for oxygen
NASA Astrophysics Data System (ADS)
Andersson, Andreas; Rutgersson, Anna; Sahlée, Erik
2016-07-01
Air-sea gas transfer velocity for O2 is calculated using directly measured fluxes with the eddy covariance technique. It is a direct method and is frequently used to determine fluxes of heat, humidity, and CO2, but has not previously been used to estimate transfer velocities for O2, using atmospheric eddy covariance data. The measured O2 fluxes are upward directed, in agreement with the measured air-sea gradient of the O2 concentration, and opposite to the direction of the simultaneously measured CO2 fluxes. The transfer velocities estimated from measurements are compared with prominent wind speed parameterizations of the transfer velocity for CO2 and O2, previously established from various measurement techniques. Our result indicates stronger wind speed dependence for the transfer velocity of O2 compared to CO2 starting at intermediate wind speeds. This stronger wind speed dependence appears to coincide with the onset of whitecap formation in the flux footprint and the strong curvature of a cubic wind-dependent function for the transfer velocity provides the best fit to the data. Additional data using the measured O2 flux and an indirect method (based on the Photosynthetic Quotient) to estimate oxygen concentration in water, support the stronger wind dependence for the transfer velocity of O2 compared to CO2.
Using eddy covariance to estimate air–sea gas transfer velocity for oxygen
NASA Astrophysics Data System (ADS)
Andersson, Andreas; Rutgersson, Anna; Sahlée, Erik
2016-07-01
Air-sea gas transfer velocity for O2 is calculated using directly measured fluxes with the eddy covariance technique. It is a direct method and is frequently used to determine fluxes of heat, humidity, and CO2, but has not previously been used to estimate transfer velocities for O2, using atmospheric eddy covariance data. The measured O2 fluxes are upward directed, in agreement with the measured air-sea gradient of the O2 concentration, and opposite to the direction of the simultaneously measured CO2 fluxes. The transfer velocities estimated from measurements are compared with prominent wind speed parameterizations of the transfer velocity for CO2 and O2, previously established from various measurement techniques. Our result indicates stronger wind speed dependence for the transfer velocity of O2 compared to CO2 starting at intermediate wind speeds. This stronger wind speed dependence appears to coincide with the onset of whitecap formation in the flux footprint and the strong curvature of a cubic wind-dependent function for the transfer velocity provides the best fit to the data. Additional data using the measured O2 flux and an indirect method (based on the Photosynthetic Quotient) to estimate oxygen concentration in water, support the stronger wind dependence for the transfer velocity of O2 compared to CO2.
Front-Crawl Instantaneous Velocity Estimation Using a Wearable Inertial Measurement Unit
Dadashi, Farzin; Crettenand, Florent; Millet, Grégoire P.; Aminian, Kamiar
2012-01-01
Monitoring the performance is a crucial task for elite sports during both training and competition. Velocity is the key parameter of performance in swimming, but swimming performance evaluation remains immature due to the complexities of measurements in water. The purpose of this study is to use a single inertial measurement unit (IMU) to estimate front crawl velocity. Thirty swimmers, equipped with an IMU on the sacrum, each performed four different velocity trials of 25 m in ascending order. A tethered speedometer was used as the velocity measurement reference. Deployment of biomechanical constraints of front crawl locomotion and change detection framework on acceleration signal paved the way for a drift-free integration of forward acceleration using IMU to estimate the swimmers velocity. A difference of 0.6 ± 5.4 cm·s−1 on mean cycle velocity and an RMS difference of 11.3 cm·s−1 in instantaneous velocity estimation were observed between IMU and the reference. The most important contribution of the study is a new practical tool for objective evaluation of swimming performance. A single body-worn IMU provides timely feedback for coaches and sport scientists without any complicated setup or restraining the swimmer's natural technique. PMID:23201978
Single Tracking Location Methods Suppress Speckle Noise in Shear Wave Velocity Estimation
Elegbe, Etana C.; McAleavey, Stephen A.
2014-01-01
In ultrasound-based elastography methods, the estimation of shear wave velocity typically involves the tracking of speckle motion due to an applied force. The errors in the estimates of tissue displacement, and thus shear wave velocity, are generally attributed to electronic noise and decorrelation due to physical processes. We present our preliminary findings on another source of error, namely, speckle-induced bias in phase estimation. We find that methods that involve tracking in a single location, as opposed to multiple locations, are less sensitive to this source of error since the measurement is differential in nature and cancels out speckle-induced phase errors. PMID:23493611
NASA Astrophysics Data System (ADS)
Shiraishi, H.; Asanuma, H.; Tezuka, K.
2010-12-01
Seismic reflection survey has been commonly used for exploration and time-lapse monitoring of oil/gas resources. Seismic reflection images typically have reasonable reliability and resolution for commercial production. However, cost consideration sometimes avoids deployment of widely distributed array or repeating survey in cases of time lapse monitoring or exploration of small-scale reservoir. Hence, technologies to estimate structures and physical properties around the reservoir with limited cost would be effectively used. Microtremor survey method (MSM) has an ability to realize long-term monitoring of reservoir with low cost, because this technique has a passive nature and minimum numbers of the monitoring station is four. MSM has been mainly used for earthquake disaster prevention, because velocity structure of S-wave is directly estimated from velocity dispersion of the Rayleigh wave. The authors experimentally investigated feasibility of the MSM survey for exploration of oil/gas reservoir. The field measurement was carried out around natural gas reservoir at Yufutsu, Hokkaido, Japan. Four types of arrays with array radii of 30m, 100m, 300m and 600m are deployed in each area. Dispersion curves of the velocity of Rayleigh wave were estimated from observed microtremors, and S-wave velocity structures were estimated by an inverse analysis of the dispersion curves with genetic algorism (GA). The estimated velocity structures showed good consistency with one dimensional velocity structure by previous reflection surveys up to 4-5 km. We also found from the field experiment that a data of 40min is effective to estimate the velocity structure even the seismometers are deployed along roads with heavy traffic.
NASA Astrophysics Data System (ADS)
Wirz, V.; Beutel, J.; Gruber, S.; Gubler, S.; Purves, R. S.
2014-09-01
Detecting and monitoring of moving and potentially hazardous slopes requires reliable estimations of velocities. Separating any movement signal from measurement noise is crucial for understanding the temporal variability of slope movements and detecting changes in the movement regime, which may be important indicators of the process. Thus, methods capable of estimating velocity and its changes reliably are required. In this paper we develop and test a method for deriving velocities based on noisy GPS (Global Positioning System) data, suitable for various movement patterns and variable signal-to-noise-ratios (SNR). We tested this method on synthetic data, designed to mimic the characteristics of diverse processes, but where we have full knowledge of the underlying velocity patterns, before applying it to explore data collected.
Cegla, H. M.; Watson, C. A.; Stassun, K. G.; Bastien, F. A.; Pepper, J.
2014-01-01
We cross match the GALEX and Kepler surveys to create a unique dataset with both ultraviolet (UV) measurements and highly precise photometric variability measurements in the visible light spectrum. As stellar activity is driven by magnetic field modulations, we have used UV emission from the magnetically heated gas in the stellar atmosphere to serve as our proxy for the more well-known stellar activity indicator, R' {sub HK}. The R' {sub HK} approximations were in turn used to estimate the level of astrophysical noise expected in radial velocity (RV) measurements and these were then searched for correlations with photometric variability. We find significant scatter in our attempts to estimate RV noise for magnetically active stars, which we attribute to variations in the phase and strength of the stellar magnetic cycle that drives the activity of these targets. However, for stars we deem to be magnetically quiet, we do find a clear correlation between photometric variability and estimated levels of RV noise (with variability up to ∼10 m s{sup –1}). We conclude that for these quiet stars, we can use photometric measurements as a proxy to estimate the RV noise expected. As a result, the procedure outlined in this paper may help select targets best-suited for RV follow-up necessary for planet confirmation.
Velocity and shear rate estimates of some non-Newtonian oscillatory flows in tubes
NASA Astrophysics Data System (ADS)
Kutev, N.; Tabakova, S.; Radev, S.
2016-10-01
The two-dimensional Newtonian and non-Newtonian (Carreau viscosity model used) oscillatory flows in straight tubes are studied theoretically and numerically. The corresponding analytical solution of the Newtonian flow and the numerical solution of the Carreau viscosity model flow show differences in velocity and shear rate. Some estimates for the velocity and shear rate differences are theoretically proved. As numerical examples the blood flow in different type of arteries and the polymer flow in pipes are considered.
Groundwater velocities at the Nevada Test Site: {sup 14}Carbon-based estimates
Chapman, J.B.; Hershey, R.L.; Lyles, B.F.
1995-07-01
Chemical and isotopic data can be used to constrain and validate groundwater flow models. This study examines probable groundwater flowpaths at the Nevada Test Site (NTS) and estimates groundwater velocities for these flowpaths using water chemistry and carbon isotopes. These velocities are provided for comparison to velocities calculated by a numerical flow model developed by GeoTrans, Inc. Similar to numerical flow models, models of chemical and isotopic evolution are not unique; any number of combinations of reactions can simulate evolution from one water to another, but are no guarantee that the simulation is correct. Knowledge of the hydrology, mineralogy, and chemistry must be combined to produce feasible evolutionary paths.
Estimating V̄s(30) (or NEHRP site classes) from shallow velocity models (depths < 30 m)
Boore, David M.
2004-01-01
The average velocity to 30 m [V??s(30)] is a widely used parameter for classifying sites to predict their potential to amplify seismic shaking. In many cases, however, models of shallow shear-wave velocities, from which V??s(30) can be computed, do not extend to 30 m. If the data for these cases are to be used, some method of extrapolating the velocities must be devised. Four methods for doing this are described here and are illustrated using data from 135 boreholes in California for which the velocity model extends to at least 30 m. Methods using correlations between shallow velocity and V??s(30) result in significantly less bias for shallow models than the simplest method of assuming that the lowermost velocity extends to 30 m. In addition, for all methods the percent of sites misclassified is generally less than 10% and falls to negligible values for velocity models extending to at least 25 m. Although the methods using correlations do a better job on average of estimating V??s(30), the simplest method will generally result in a lower value of V??s(30) and thus yield a more conservative estimate of ground motion [which generally increases as V??s(30) decreases].
Preliminary Estimates of Specific Discharge and TransportVelocities near Borehole NC-EWDP-24PB
Freifeld, Barry; Doughty, Christine; Finsterle, Stefan
2006-06-21
This report summarizes fluid electrical conductivity (FEC)and thermal logging data collected in Borehole NC-EWDP-24PB, locatedapproximately 15 km south of the proposed repository at Yucca Mountain.Preliminary analyses of a small fraction of the FEC and temperature dataindicate that relatively large, localized fluid fluxes are likely toexist at this location. The implication that considerable flow is inducedby small gradients, and that flow is highly localized, is significant forthe estimation of groundwater transport velocities and radionuclidetravel times. The sensitivity of the data to potential perturbationsduring testing (i.e., internal wellbore flow in the case of FEC data, andbuoyancy effects in the case of thermal logging data) make it difficultto conclusively derive fluid fluxes and transport velocities without adetailed analysis of all data and processes involved. Such acomprehensive analysis has not yet been performed. However, thepreliminary results suggest that the ambient component of the estimatedflow rates is significant and on the order of liters per minute, yieldinggroundwater transport velocities in the range of kilometers per year. Oneparticular zone in the Bullfrog tuff exhibits estimated velocities on theorder of 10 km/yr. Given that the preliminary estimates of ambient flowrates and transport velocities are relatively high, and considering thepotential impact of high rates and velocities on saturated-zone flow andtransport behavior, we recommend that a comprehensive analysis of all theavailable data be performed. Moreover, additional data sets at otherlocations should be collected to examine whether the current data set isrepresentative of the regional flow system near YuccaMountain.
Satellite angular velocity estimation based on star images and optical flow techniques.
Fasano, Giancarmine; Rufino, Giancarlo; Accardo, Domenico; Grassi, Michele
2013-09-25
An optical flow-based technique is proposed to estimate spacecraft angular velocity based on sequences of star-field images. It does not require star identification and can be thus used to also deliver angular rate information when attitude determination is not possible, as during platform de tumbling or slewing. Region-based optical flow calculation is carried out on successive star images preprocessed to remove background. Sensor calibration parameters, Poisson equation, and a least-squares method are then used to estimate the angular velocity vector components in the sensor rotating frame. A theoretical error budget is developed to estimate the expected angular rate accuracy as a function of camera parameters and star distribution in the field of view. The effectiveness of the proposed technique is tested by using star field scenes generated by a hardware-in-the-loop testing facility and acquired by a commercial-off-the shelf camera sensor. Simulated cases comprise rotations at different rates. Experimental results are presented which are consistent with theoretical estimates. In particular, very accurate angular velocity estimates are generated at lower slew rates, while in all cases the achievable accuracy in the estimation of the angular velocity component along boresight is about one order of magnitude worse than the other two components.
Satellite Angular Velocity Estimation Based on Star Images and Optical Flow Techniques
Fasano, Giancarmine; Rufino, Giancarlo; Accardo, Domenico; Grassi, Michele
2013-01-01
An optical flow-based technique is proposed to estimate spacecraft angular velocity based on sequences of star-field images. It does not require star identification and can be thus used to also deliver angular rate information when attitude determination is not possible, as during platform de tumbling or slewing. Region-based optical flow calculation is carried out on successive star images preprocessed to remove background. Sensor calibration parameters, Poisson equation, and a least-squares method are then used to estimate the angular velocity vector components in the sensor rotating frame. A theoretical error budget is developed to estimate the expected angular rate accuracy as a function of camera parameters and star distribution in the field of view. The effectiveness of the proposed technique is tested by using star field scenes generated by a hardware-in-the-loop testing facility and acquired by a commercial-off-the shelf camera sensor. Simulated cases comprise rotations at different rates. Experimental results are presented which are consistent with theoretical estimates. In particular, very accurate angular velocity estimates are generated at lower slew rates, while in all cases the achievable accuracy in the estimation of the angular velocity component along boresight is about one order of magnitude worse than the other two components. PMID:24072023
NASA Astrophysics Data System (ADS)
Ikari, Yohei; Hirata, Shinnosuke; Hachiya, Hiroyuki
2015-07-01
Pulse compression using a maximum-length sequence (M-sequence) can improve the signal-to-noise ratio (SNR) of the reflected echo in the pulse-echo method. In the case of a moving object, however, the echo is modulated owing to the Doppler effect. The Doppler-shifted M-sequence-modulated signal cannot be correlated with the reference signal that corresponds to the transmitted M-sequence-modulated signal. Therefore, Doppler velocity estimation by spectrum-pattern analysis of a cyclic M-sequence-modulated signal and cross correlations with Doppler-shifted reference signals that correspond to the estimated Doppler velocities has been proposed. In this paper, measurements of the position and velocity of a moving object by the proposed method are described. First, Doppler velocities of the object are estimated using a microphone array. Secondly, the received signal from each microphone is correlated with each Doppler-shifted reference signal. Then, the position of the object is determined from the B-mode image formed from all cross-correlation functions. After that, the velocity of the object is calculated from velocity components estimated from the Doppler velocities and the position. Finally, the estimated Doppler velocities, determined positions, and calculated velocities are evaluated.
Estimation of near-surface shear-wave velocity by inversion of Rayleigh waves
Xia, J.; Miller, R.D.; Park, C.B.
1999-01-01
The shear-wave (S-wave) velocity of near-surface materials (soil, rocks, pavement) and its effect on seismic-wave propagation are of fundamental interest in many groundwater, engineering, and environmental studies. Rayleigh-wave phase velocity of a layered-earth model is a function of frequency and four groups of earth properties: P-wave velocity, S-wave velocity, density, and thickness of layers. Analysis of the Jacobian matrix provides a measure of dispersion-curve sensitivity to earth properties. S-wave velocities are the dominant influence on a dispersion curve in a high-frequency range (>5 Hz) followed by layer thickness. An iterative solution technique to the weighted equation proved very effective in the high-frequency range when using the Levenberg-Marquardt and singular-value decomposition techniques. Convergence of the weighted solution is guaranteed through selection of the damping factor using the Levenberg-Marquardt method. Synthetic examples demonstrated calculation efficiency and stability of inverse procedures. We verify our method using borehole S-wave velocity measurements.Iterative solutions to the weighted equation by the Levenberg-Marquardt and singular-value decomposition techniques are derived to estimate near-surface shear-wave velocity. Synthetic and real examples demonstrate the calculation efficiency and stability of the inverse procedure. The inverse results of the real example are verified by borehole S-wave velocity measurements.
NASA Astrophysics Data System (ADS)
Estrada, Antonio; Efimov, Denis; Perruquetti, Wilfrid
2016-09-01
The present work focuses on the problem of velocity and position estimation. A solution is presented for a class of oscillating systems in which position, velocity and acceleration are zero mean signals. The proposed scheme considers that the dynamic model of the system is unknown. Only noisy acceleration measurements, that may be contaminated by zero mean noise and constant bias, are considered to be available. The proposal uses the periodic nature of the signals obtaining finite-time estimations while tackling integration drift accumulation.
Han, Wenhua; Shen, Xiaohui; Xu, Jun; Wang, Ping; Tian, Guiyun; Wu, Zhengyang
2014-01-01
Magnetic flux leakage (MFL) inspection is one of the most important and sensitive nondestructive testing approaches. For online MFL inspection of a long-range railway track or oil pipeline, a fast and effective defect profile estimating method based on a multi-power affine projection algorithm (MAPA) is proposed, where the depth of a sampling point is related with not only the MFL signals before it, but also the ones after it, and all of the sampling points related to one point appear as serials or multi-power. Defect profile estimation has two steps: regulating a weight vector in an MAPA filter and estimating a defect profile with the MAPA filter. Both simulation and experimental data are used to test the performance of the proposed method. The results demonstrate that the proposed method exhibits high speed while maintaining the estimated profiles clearly close to the desired ones in a noisy environment, thereby meeting the demand of accurate online inspection. PMID:25192314
Stationary echo canceling in velocity estimation by time-domain cross-correlation.
Jensen, J A
1993-01-01
The application of stationary echo canceling to ultrasonic estimation of blood velocities using time-domain cross-correlation is investigated. Expressions are derived that show the influence from the echo canceler on the signals that enter the cross-correlation estimator. It is demonstrated that the filtration results in a velocity-dependent degradation of the signal-to-noise ratio. An analytic expression is given for the degradation for a realistic pulse. The probability of correct detection at low signal-to-noise ratios is influenced by signal-to-noise ratio, transducer bandwidth, center frequency, number of samples in the range gate, and number of A-lines employed in the estimation. Quantitative results calculated by a simple simulation program are given for the variation in probability from these parameters. An index reflecting the reliability of the estimate at hand can be calculated from the actual cross-correlation estimate by a simple formula and used in rejecting poor estimates or in displaying the reliability of the velocity estimated.
Ice Velocity Estimation Using SAR Data in PANDA Section, East Antarctica
NASA Astrophysics Data System (ADS)
Deng, F.; Zhou, C.; Zhou, Y.
2015-12-01
Ice-flow velocity is a significant parameter in dynamic models of the Antarctic ice sheet, indicating how ice is transported from the interior to the ocean and how ice mass evolves. PANDA (Prydz Bay - Amery Ice shelf - Dome A) section is the key area of Chinese expedition in the Antarctic, and many scientific studies have been conducted here. In this research, SAR images including ERS-1/2, Envisat and ALOS were applied to estimate the ice velocity of PANDA Section using DInSAR and offset-tracking methods. Compared to MEaSUREs velocity (ice velocity map of the Antarctic released by National Snow and Ice Data Center) of 450 m resolution, our result with 200 m resolution achieved similar accuracy. Ice mass of PANDA section flows into the ocean mainly through Amery Ice Shelf and Polar Record Glacier. The ice velocity at the front edge of Amery Ice shelf is almost 1500 m/a, and the ice velocity of Polar Record Glacier can reach as high as 800 m/a. At most inner area of PANDA section, ice velocity is below 40 m/a. Due to the blocking of rocks and nunataks, ice flow feature in Grove Mountains area is quite complicated, which can help to demonstrate the meteorite concentration mechanism in this area.
NASA Astrophysics Data System (ADS)
Takagi, R.; Uchida, N.; Okada, T.; Hasegawa, A.
2012-12-01
We analyzed repeating earthquake data to estimate velocity change in the overriding plate in NE Japan associated with the 2011 M9.0 Tohoku-Oki earthquake. Because repeating earthquakes occur as the repeating slips on the same patch on the Pacific plate with the same source mechanism at different time, waveform data of repeating earthquake is suitable for detecting temporal change in subsurface structure. We tried to use the direct part of seismograms to estimate location of the velocity change. This is because the time-shift in direct part simply reflects the velocity change only along a direct ray path in contrast to the complex path of coda waves. We analyzed repeating earthquake records from 2003 to December 2011. The travel time shifts before and after the Tohoku-Oki earthquake are measured by the cross-spectral method in the frequency range of 1-10 Hz. One problem for using the direct part is an error of origin time. However, because the errors of origin times are identical at all stations, we can estimate the relative delay in many stations for a pair of repeating earthquakes that can be used for the estimation of the spatial variation of time-shift in direct part. After removing outliers, we subtracted a mean of the time-shifts of direct P wave for all stations from the time-shifts of P and S wave at every station. From the result of many repeating earthquake sequences, we can recognize clear relative time delays of approximately 0.01 sec for S wave in both the fore-arc and back-arc region from Fukushima to Iwate prefecture. The travel-time delays of P wave are approximately 3 times smaller than those of S wave. From a consideration of observed travel time shifts and ray paths, the velocity change seems to distribute in land area. One possible mechanism of the receiver-side velocity reduction is crack opening as a result of the static stress change due to coseismic slip on the plate boundary. The velocity change due to the static stress change can be
Estimation of seabed shear-wave velocity profiles using shear-wave source data.
Dong, Hefeng; Nguyen, Thanh-Duong; Duffaut, Kenneth
2013-07-01
This paper estimates seabed shear-wave velocity profiles and their uncertainties using interface-wave dispersion curves extracted from data generated by a shear-wave source. The shear-wave source generated a seismic signature over a frequency range between 2 and 60 Hz and was polarized in both in-line and cross-line orientations. Low-frequency Scholte- and Love-waves were recorded. Dispersion curves of the Scholte- and Love-waves for the fundamental mode and higher-order modes are extracted by three time-frequency analysis methods. Both the vertically and horizontally polarized shear-wave velocity profiles in the sediment are estimated by the Scholte- and Love-wave dispersion curves, respectively. A Bayesian approach is utilized for the inversion. Differential evolution, a global search algorithm is applied to estimate the most-probable shear-velocity models. Marginal posterior probability profiles are computed by Metropolis-Hastings sampling. The estimated vertically and horizontally polarized shear-wave velocity profiles fit well with the core and in situ measurements. PMID:23862796
An empirical method to estimate shear wave velocity of soils in the New Madrid seismic zone
Wei, B.-Z.; Pezeshk, S.; Chang, T.-S.; Hall, K.H.; Liu, Huaibao P.
1996-01-01
In this study, a set of charts are developed to estimate shear wave velocity of soils in the New Madrid seismic zone (NMSZ), using the standard penetration test (SPT) N values and soil depths. Laboratory dynamic test results of soil samples collected from the NMSZ showed that the shear wave velocity of soils is related to the void ratio and the effective confining pressure applied to the soils. The void ratio of soils can be estimated from the SPT N values and the effective confining pressure depends on the depth of soils. Therefore, the shear wave velocity of soils can be estimated from the SPT N value and the soil depth. To make the methodology practical, two corrections should be made. One is that field SPT N values of soils must be adjusted to an unified SPT N??? value to account the effects of overburden pressure and equipment. The second is that the effect of water table to effective overburden pressure of soils must be considered. To verify the methodology, shear wave velocities of five sites in the NMSZ are estimated and compared with those obtained from field measurements. The comparison shows that our approach and the field tests are consistent with an error of less than of 15%. Thus, the method developed in this study is useful for dynamic study and practical designs in the NMSZ region. Copyright ?? 1996 Elsevier Science Limited.
Bredbeck, T; Rodgers, A; Walter, W
1999-07-23
The velocity structures and source parameters estimated by waveform modeling provide valuable information for CTBT monitoring. The inferred crustal and uppermost mantle structures advance understanding of tectonics and guides regionalization for event location and identification efforts. Estimation of source parameters such as seismic moment, depth and mechanism (whether earthquake, explosion or collapse) is crucial to event identification. In this paper we briefly outline some of the waveform modeling research for CTBT monitoring performed in the last year. In the future we will estimate structure for new regions by modeling waveforms of large well-observed events along additional paths. Of particular interest will be the estimation of velocity structure in aseismic regions such as most of Africa and the Former Soviet Union. Our previous work on aseismic regions in the Middle East, north Africa and south Asia give us confidence to proceed with our current methods. Using the inferred velocity models we plan to estimate source parameters for smaller events. It is especially important to obtain seismic moments of earthquakes for use in applying the Magnitude-Distance Amplitude Correction (MDAC; Taylor et al., 1999) to regional body-wave amplitudes for discrimination and calibrating the coda-based magnitude scales.
Estimation of friction velocity from the wind-wave spectrum at extremely high wind speeds
NASA Astrophysics Data System (ADS)
Takagaki, N.; Komori, S.; Suzuki, N.
2016-05-01
The equilibrium range of wind-waves at normal and extremely high wind speeds was investigated experimentally using a high-speed wind-wave tank together with field measurements at normal wind speeds. Water level fluctuations at normal and extremely high wind speeds were measured with resistance-type wave gauges, and the wind-wave spectrum and significant phase velocity were calculated. The equilibrium range constant was estimated from the wind-wave spectrum and showed the strong relationship with inverse wave age at normal and extremely high wind speeds. Using the strong relation between the equilibrium range constant and inverse wave age, a new method for estimating the wind speed at 10-m height (U 10) and friction velocity (u*) was proposed. The results suggest that U 10 and u* can be estimated from wave measurements alone at extremely high wind speeds in oceans under tropical cyclones.
Three-dimensional object motion and velocity estimation using a single computational RGB-D camera.
Lee, Seungwon; Jeong, Kyungwon; Park, Jinho; Paik, Joonki
2015-01-08
In this paper, a three-dimensional (3D) object moving direction and velocity estimation method is presented using a dual off-axis color-filtered aperture (DCA)-based computational camera. Conventional object tracking methods provided only two-dimensional (2D) states of an object in the image for the target representation. The proposed method estimates depth information in the object region from a single DCA camera that transforms 2D spatial information into 3D model parameters of the object. We also present a calibration method of the DCA camera to estimate the entire set of camera parameters for a practical implementation. Experimental results show that the proposed DCA-based color and depth (RGB-D) camera can calculate the 3D object moving direction and velocity of a randomly moving object in a single-camera framework.
NASA Astrophysics Data System (ADS)
Kinsey, J. C.; Yoerger, D. R.; Camilli, R.; German, C. R.
2010-12-01
Water velocity measurements are crucial to quantifying fluxes and better understanding water as a fundamental transport mechanism for marine chemical and biological processes. The importance of flux to understanding these processes makes it a crucial component of astrobiological exploration to moons possessing large bodies of water, such as Europa. Present technology allows us to obtain submerged water velocity measurements from stationary platforms; rarer are measurements from submerged vehicles which possess the ability to autonomously survey tens of kilometers over extended periods. Improving this capability would also allow us to obtain co-registered water velocity and other sensor data (e.g., mass spectrometers, temperature, oxygen, etc) and significantly enhance our ability to estimate fluxes. We report results from 4 recent expeditions in which we measured water velocities from autonomous underwater vehicles (AUVs) to help quantify flux in three different oceanographic contexts: hydrothermal vent plumes; an oil spill cruise responding to the 2010 Deepwater Horizon blowout; and two expeditions investigating naturally occurring methane seeps. On all of these cruises, we directly measured the water velocities with an acoustic Doppler current profiler (ADCP) mounted on the AUV. Vehicle motion was corrected for using bottom-lock Doppler tracks when available and, in the absence of bottom-lock, estimates of vehicle velocity based on dynamic models. In addition, on the methane seep cruises, we explored the potential of using acoustic mapping sonars, such as multi-beam and sub-bottom profiling systems, to localize plumes and indirectly quantify flux. Data obtained on these expeditions enhanced our scientific investigations and provides data for future development of algorithms for autonomously processing, identifying, and classifying water velocity and flux measurements. Such technology will be crucial in future astrobiology missions where highly constrained
Site-effect estimations for Taipei Basin based on shallow S-wave velocity structures
NASA Astrophysics Data System (ADS)
Chen, Ying-Chi; Huang, Huey-Chu; Wu, Cheng-Feng
2016-03-01
Shallow S-wave velocities have been widely used for earthquake ground-motion site characterization. Thus, the S-wave velocity structures of Taipei Basin, Taiwan were investigated using array records of microtremors at 15 sites (Huang et al., 2015). In this study, seven velocity structures are added to the database describing Taipei Basin. Validity of S-wave velocity structures are first examined using the 1D Haskell method and well-logging data at the Wuku Sewage Disposal Plant (WK) borehole site. Basically, the synthetic results match well with the observed data at different depths. Based on S-wave velocity structures at 22 sites, theoretical transfer functions at five different formations of the sedimentary basin are calculated. According to these results, predominant frequencies for these formations are estimated. If the S-wave velocity of the Tertiary basement is assumed to be 1000 m/s, the predominant frequencies of the Quaternary sediments are between 0.3 Hz (WUK) and 1.4 Hz (LEL) in Taipei Basin while the depths of sediments between 0 m (i.e. at the edge of the basin) and 616 m (i.e. site WUK) gradually increase from southeast to northwest. Our results show good agreement with available geological and geophysical information.
Method of LSD profile asymmetry for estimating the center of mass velocities of pulsating stars
NASA Astrophysics Data System (ADS)
Britavskiy, Nikolay; Pancino, Elena; Romano, Donatella; Tsymbal, Vadim
2015-08-01
We present radial velocity analysis for 20 solar neighborhood RR Lyrae and 3 Population II Cepheids. High-resolution spectra were observed with either TNG/SARG or VLT/UVES over varying phases. To estimate the center of mass (barycentric) velocities of the program stars, we utilized two independent methods. First, the 'classic' method was employed, which is based on RR Lyrae radial velocity curve templates. Second, we provide the new method that used absorption line profile asymmetry to determine both the pulsation and the barycentric velocities even with a low number of high-resolution spectra and in cases where the phase of the observations is uncertain. This new method is based on a Least Squares Deconvolution (LSD) of the line profiles in order to analyze line asymmetry that occurs in the spectra of pulsating stars. By applying this method to our sample stars we attain accurate measurements (± 1 km/s) of the pulsation component of the radial velocity. This results in determination of the barycentric velocity to within 5 km/s even with a low number of high-resolution spectra. A detailed investigation of LSD profile asymmetry shows the variable nature of the project factor at different pulsation phases, which should be taken into account in the detailed spectroscopic analysis of pulsating stars.
Method of LSD profile asymmetry for estimating the center of mass velocities of pulsating stars
NASA Astrophysics Data System (ADS)
Britavskiy, N.; Pancino, E.; Tsymbal, V.; Romano, D.; Cacciari, C.; Clementini, C.
2016-05-01
We present radial velocity analysis for 20 solar neighborhood RR Lyrae and 3 Population II Cepheids. High-resolution spectra were observed with either TNG/SARG or VLT/UVES over varying phases. To estimate the center of mass (barycentric) velocities of the program stars, we utilized two independent methods. First, the 'classic' method was employed, which is based on RR Lyrae radial velocity curve templates. Second, we provide the new method that used absorption line profile asymmetry to determine both the pulsation and the barycentric velocities even with a low number of high-resolution spectra and in cases where the phase of the observations is uncertain. This new method is based on a least squares deconvolution (LSD) of the line profiles in order to an- alyze line asymmetry that occurs in the spectra of pulsating stars. By applying this method to our sample stars we attain accurate measurements (+- 2 kms^-1) of the pulsation component of the radial velocity. This results in determination of the barycentric velocity to within 5 kms^-1 even with a low number of high- resolution spectra. A detailed investigation of LSD profile asymmetry shows the variable nature of the project factor at different pulsation phases, which should be taken into account in the detailed spectroscopic analysis of pulsating stars.
Pasciuto, Ilaria; Ligorio, Gabriele; Bergamini, Elena; Vannozzi, Giuseppe; Sabatini, Angelo Maria; Cappozzo, Aurelio
2015-09-18
In human movement analysis, 3D body segment orientation can be obtained through the numerical integration of gyroscope signals. These signals, however, are affected by errors that, for the case of micro-electro-mechanical systems, are mainly due to: constant bias, scale factor, white noise, and bias instability. The aim of this study is to assess how the orientation estimation accuracy is affected by each of these disturbances, and whether it is influenced by the angular velocity magnitude and 3D distribution across the gyroscope axes. Reference angular velocity signals, either constant or representative of human walking, were corrupted with each of the four noise types within a simulation framework. The magnitude of the angular velocity affected the error in the orientation estimation due to each noise type, except for the white noise. Additionally, the error caused by the constant bias was also influenced by the angular velocity 3D distribution. As the orientation error depends not only on the noise itself but also on the signal it is applied to, different sensor placements could enhance or mitigate the error due to each disturbance, and special attention must be paid in providing and interpreting measures of accuracy for orientation estimation algorithms.
A dual sensor device to estimate fluid flow velocity at diffuse hydrothermal vents
NASA Astrophysics Data System (ADS)
Sarrazin, J.; Rodier, P.; Tivey, M. K.; Singh, H.; Schultz, A.; Sarradin, P. M.
2009-11-01
Numerous attempts have been made over the last thirty years to estimate fluid flow rates at hydrothermal vents, either at the exit of black smoker chimneys or within diffuse flow areas. In this study, we combine two methods to accurately estimate fluid flow velocities at diffuse flow areas. While the first method uses a hot film anemometer that performs high-frequency measurements, the second allows a relatively rapid assessment of fluid flow velocity through video imagery and provides in situ data to calibrate the sensor. Measurements of flow velocities on hydrothermal diffuse flow areas were obtained on the Mid-Atlantic Ridge (MAR). They range from 1.1 to 4.9 mm/s at the substratum level, in low-temperature (4.5-16.4 °C) diffuse flow areas from the Tour Eiffel sulfide edifice. A strong correlation was observed between fluid flow velocities and temperature, supporting the possible use of temperature as a proxy to estimate the flow rates in diffuse flow areas where such a simple linear flow/temperature relation is shown to dominate.
Pasciuto, Ilaria; Ligorio, Gabriele; Bergamini, Elena; Vannozzi, Giuseppe; Sabatini, Angelo Maria; Cappozzo, Aurelio
2015-01-01
In human movement analysis, 3D body segment orientation can be obtained through the numerical integration of gyroscope signals. These signals, however, are affected by errors that, for the case of micro-electro-mechanical systems, are mainly due to: constant bias, scale factor, white noise, and bias instability. The aim of this study is to assess how the orientation estimation accuracy is affected by each of these disturbances, and whether it is influenced by the angular velocity magnitude and 3D distribution across the gyroscope axes. Reference angular velocity signals, either constant or representative of human walking, were corrupted with each of the four noise types within a simulation framework. The magnitude of the angular velocity affected the error in the orientation estimation due to each noise type, except for the white noise. Additionally, the error caused by the constant bias was also influenced by the angular velocity 3D distribution. As the orientation error depends not only on the noise itself but also on the signal it is applied to, different sensor placements could enhance or mitigate the error due to each disturbance, and special attention must be paid in providing and interpreting measures of accuracy for orientation estimation algorithms. PMID:26393606
ESTIMATION OF S-WAVE VELOCITY STRUCTURE OF FUKUI PLAIN BASED ON MICROTREMOR ARRAY OBSERVATION
NASA Astrophysics Data System (ADS)
Kojima, Keisuke; Moto, Koudai
The precise evaluations of Quaternary structure of the region are indispensable in order to accurately predict the seismic damage. However, deep borehole, PS-logging and elastic wave exploration have been executed only on limited points around the Fukui Plain. The problem analyzed in this study is statistical estimation of the 3D S-wave velocity structure down to the Tertiary bedrock of the Fukui Plain based on the data from 75 microtremor array observation sites. The Rayleigh wave phase velocities at each array site were calculated by the spatial autocorrelation method. The phase velocities at each site were inverted to a 1D S-wave profile using a genetic inversion. The 3-components single-site microtremor observations were carried out to compensate the array observations. The 3D S-wave velocity structure around the Fukui plain have been interpolated by using Kriging and Co-Kriging techniques. In the Co-Kriging procedure, the correlations between the estimated depths of Quaternary and the observed predominant periods of the sites were taken into account. The validity of the estimated structure from the microtremor observation was confirmed by comparing with the density structure and with the existing PS-logging data.
Estimation of pseudo-2D shear-velocity section by inversion of high frequency surface waves
Luo, Y.; Liu, J.; Xia, J.; Xu, Y.; Liu, Q.
2006-01-01
A scheme to generate pseudo-2D shear-velocity sections with high horizontal resolution and low field cost by inversion of high frequency surface waves is presented. It contains six steps. The key step is the joint method of crossed correlation and phase shift scanning. This joint method chooses only two traces to generate image of dispersion curve. For Rayleigh-wave dispersion is most important for estimation of near-surface shear-wave velocity, it can effectively obtain reliable images of dispersion curves with a couple of traces. The result of a synthetic example shows the feasibility of this scheme. ?? 2005 Society of Exploration Geophysicists.
Uncertainty estimation of the velocity model for stations of the TrigNet GPS network
NASA Astrophysics Data System (ADS)
Hackl, M.; Malservisi, R.; Hugentobler, U.
2010-12-01
Satellite based geodetic techniques - above all GPS - provide an outstanding tool to measure crustal motions. They are widely used to derive geodetic velocity models that are applied in geodynamics to determine rotations of tectonic blocks, to localize active geological features, and to estimate rheological properties of the crust and the underlying asthenosphere. However, it is not a trivial task to derive GPS velocities and their uncertainties from positioning time series. In general time series are assumed to be represented by linear models (sometimes offsets, annual, and semi-annual signals are included) and noise. It has been shown that error models accounting only for white noise tend to underestimate the uncertainties of rates derived from long time series and that different colored noise components (flicker noise, random walk, etc.) need to be considered. However, a thorough error analysis including power spectra analyses and maximum likelihood estimates is computationally expensive and is usually not carried out for every site, but the uncertainties are scaled by latitude dependent factors. Analyses of the South Africa continuous GPS network TrigNet indicate that the scaled uncertainties overestimate the velocity errors. So we applied a method similar to the Allan Variance that is commonly used in the estimation of clock uncertainties and is able to account for time dependent probability density functions (colored noise) to the TrigNet time series. Comparisons with synthetic data show that the noise can be represented quite well by a power law model in combination with a seasonal signal in agreement with previous studies, which allows for a reliable estimation of the velocity error. Finally, we compared these estimates to the results obtained by spectral analyses using CATS. Small differences may originate from non-normal distribution of the noise.
Estimates of the seasonal mean vertical velocity fields of the extratropical Northern Hemisphere
NASA Technical Reports Server (NTRS)
White, G. H.
1983-01-01
Indirect methods are employed to estimate the wintertime and summertime mean vertical velocity fields of the extratropical Northern Hemisphere and intercomparisons are made, together with comparisons with mean seasonal patterns of cloudiness and precipitation. Twice-daily NMC operational analyses produced general circulation statistics for 11 winters and 12 summers, permitting calculation of the seasonal NMC averages for 6 hr forecasts, solution of the omega equation, integration of continuity equation downward from 100 mb, and solution of the thermodynamic energy equation in the absence of diabatic heating. The methods all yielded similar vertical velocity patterns; however, the magnitude of the vertical velocities could not be calculated with great accuracy. Orography was concluded to have less of an effect in summer than in winter, when winds are stronger.
Gallina, Alessio; Ritzel, Cintia H; Merletti, Roberto; Vieira, Taian M M
2013-04-01
Muscle fiber conduction velocity (CV) is commonly estimated from surface electromyograms (EMGs) collected with electrodes parallel to muscle fibers. If electrodes and muscle fibers are not located in parallel planes, CV estimates are biased towards values far over the physiological range. In virtue of their pinnate architecture, the fibers of muscles such as the gastrocnemius are hardly aligned in planes parallel to surface electrodes. Therefore, in this study we investigate whether physiological CV estimates can be obtained from the gastrocnemius muscle. Specifically, with a large grid of 16×8 electrodes we map CV estimates over the whole gastrocnemius muscle while eleven subjects exerted isometric plantar flexions at three different force levels. CV was estimated for couples of single differential EMGs and estimate locations (i.e., channels) were classified as physiological and non-physiological, depending on whether CV estimates were within the physiological range (3-6ms(-1)) or not. Physiological CV values could be estimated from a markedly small muscle region for eight participants; channels providing physiological CV estimates corresponded to about 5% of the total number of channels. As expected, physiological and non-physiological channels were clustered in distinct regions. CV estimates within the physiological range were obtained for the most distal gastrocnemius portion (ANOVA, P<0.001), where occurrences of propagating potentials were often verified through visual analysis. For the first time, this study shows that CV might be reliably assessed from surface EMGs collected from the most distal gastrocnemius region.
Shear wave velocity estimation in the metropolitan area of Málaga (S Spain)
NASA Astrophysics Data System (ADS)
Clavero, D.; Rosa-Cintas, S.; López-Casado, C.; Delgado, J.; Galiana-Merino, J. J.
2014-10-01
We carry out a seismic noise study based on array measurements at three sites in the Málaga basin, South Spain, for the further estimation of shear wave velocity profiles. For this purpose, we use both the H/V method and the f-k technique in order to characterize the different materials present in the zone, i.e., Quaternary sediments and Pliocene sedimentary rocks above the bedrock. The H/V analysis shows frequency peaks going from 1 Hz, in areas close to the border of the basin, to 0.3 Hz in places located toward the center of the formation. The f-k analysis allows obtaining the dispersion curves associated with each site and subsequently, estimating the Vs profiles by inversion of the respective group velocities. In this way, the basin basement can be characterized by S-wave velocities greater than 2000 m/s. Regarding the basin fill, it is divided into three layers defined by different wave velocity intervals. The shallowest one is featured by velocities ranging from 150 to 400 m/s and comprises the Quaternary sediments, while velocities going from 550-700 to1200-1600 m/s characterize the two underlying layers composed by Pliocene sediments. Finally, the information provided by the three Vs profiles is integrated in a 2D cross-section of the basin to have a spatial view of its sedimentary structure. The results obtained here, in addition to providing useful information about the infill of the basin near the metropolitan area of Málaga, will be very helpful for future seismic zonation studies in the region.
Estimating wave orbital velocity through the azimuth cutoff from space-borne satellites
NASA Astrophysics Data System (ADS)
Stopa, Justin E.; Ardhuin, Fabrice; Chapron, Bertrand; Collard, Fabrice
2015-11-01
It has been long accepted that ocean wave conditions recorded from synthetic aperture radar (SAR) aboard satellites resolve large scale swells. SARs make use of its displacement to achieve fine resolution; however the random surface motions can reduce its nominal azimuthal resolution. Accordingly, the SAR spectral azimuth response mirrors the probability distribution of the radial velocity component of the scatters. This effect, quantified in a measure called the azimuth cutoff, is estimated by defining a scale based on the fitting of a Gaussian function to the radar cross section azimuth spectrum. The independent measure provides additional sea state information related to the root mean square surface orbital wave velocity. We use data recorded from the European Space Agency's ENVISAT advanced SAR in the C-band spanning its lifetime 2003-2012. Our purpose is to first establish the validity of the azimuth cutoff using both colocated buoys and modeled wave data. Some systematic biases are corrected using other SAR derived parameters, improving the accuracy of the estimate. Despite our efforts, errors exist in the presence of swell, extreme wind waves, and related to the wave direction. Under the majority of the sea states the parameter is well behaved. As a final point, applications using the wave orbital velocities are described in terms of diagnosing a spectral wave model and the wave climate. As illustrated, the returned radar signal provides useful sea state information that resolves wind speeds, wave orbital velocities from the wind waves, and swells.
Rapid analysis of non-uniformly sampled pulsed field gradient data for velocity estimation.
Raghavan, K; Park, J C; Pavlovskaya, G E; Gibbs, S J
2001-06-01
Bretthorst's recent generalization of the Lomb-Scargle periodogram shows that a sufficient statistic for frequency estimation from non-uniformly, but simultaneously sampled quadrature data is equivalent to the FFT of those data with the missing samples replaced by zeros. We have applied this concept to the rapid analysis of pulsed field gradient MRI data which have been non-uniformly sampled in the velocity encoding wave vector q. For a small number of q samples, it is more computationally efficient to calculate the periodogram directly rather than using the FFT algorithm with a large number of zeros. The algorithm we have implemented for finding the peak of the generalized periodogram is simple and robust; it involves repeated apodization and grid searching of the periodogram until the desired velocity resolution is achieved. The final estimate is refined by quadratic interpolation. We have tested the method for fully developed Poiseuille flow of a Newtonian fluid and have demonstrated substantial improvement in the precision of velocity measurement achievable in a fixed acquisition time with non-uniform sampling. The method is readily extendible to multidimensional data. Analysis of a 256 by 256 pixel image with 8 q samples and an effective velocity resolution of better than 1/680 of the Nyquist range requires approximately 1 minute computation time on a 400 MHz SUN Ultrasparc II processor. PMID:11672628
Estimating fracture parameters from p-wave velocity profiles about a geothermal well
Jenkinson, J.T.; Henyey, T.L.; Sammis, C.G.; Leary, P.C.; McRaney, J.K.
1981-12-01
The feasibility of locating fracture zones and estimating their crack parameters was examined using an areal well shoot method centered on Utah State Geothermal Well 9-1, Beaver County, Utah. High-resolution travel time measurements were made between a borehole sensor and an array of shot stations distributed radially and azimuthally about the well. Directional velocity behavior in the vicinity of the well was investigated by comparing velocity logs derived from the travel time data. Three fracture zones were identified form the velocity data, corroborating fracture indicators seen in other geophysical logs conducted in Well 9-1. Crack densities and average crack aspect ratios for these fracture zones were estimated using a self-consistent velocity theory (O'Connell and Budiansy 1974). Probable trends of these fracture zones were established from a combination of the data from the more distant shot stations and the results of a gravity survey. The results of this study indicate that the areal well shoot is a potentially powerful tool for the reconnaisance of fracture-controlled fluid and gas reservoirs. Improvements in methodology and hardware could transform it into an operationally viable survey method.
An algorithm to estimate unsteady and quasi-steady pressure fields from velocity field measurements.
Dabiri, John O; Bose, Sanjeeb; Gemmell, Brad J; Colin, Sean P; Costello, John H
2014-02-01
We describe and characterize a method for estimating the pressure field corresponding to velocity field measurements such as those obtained by using particle image velocimetry. The pressure gradient is estimated from a time series of velocity fields for unsteady calculations or from a single velocity field for quasi-steady calculations. The corresponding pressure field is determined based on median polling of several integration paths through the pressure gradient field in order to reduce the effect of measurement errors that accumulate along individual integration paths. Integration paths are restricted to the nodes of the measured velocity field, thereby eliminating the need for measurement interpolation during this step and significantly reducing the computational cost of the algorithm relative to previous approaches. The method is validated by using numerically simulated flow past a stationary, two-dimensional bluff body and a computational model of a three-dimensional, self-propelled anguilliform swimmer to study the effects of spatial and temporal resolution, domain size, signal-to-noise ratio and out-of-plane effects. Particle image velocimetry measurements of a freely swimming jellyfish medusa and a freely swimming lamprey are analyzed using the method to demonstrate the efficacy of the approach when applied to empirical data.
An algorithm to estimate unsteady and quasi-steady pressure fields from velocity field measurements.
Dabiri, John O; Bose, Sanjeeb; Gemmell, Brad J; Colin, Sean P; Costello, John H
2014-02-01
We describe and characterize a method for estimating the pressure field corresponding to velocity field measurements such as those obtained by using particle image velocimetry. The pressure gradient is estimated from a time series of velocity fields for unsteady calculations or from a single velocity field for quasi-steady calculations. The corresponding pressure field is determined based on median polling of several integration paths through the pressure gradient field in order to reduce the effect of measurement errors that accumulate along individual integration paths. Integration paths are restricted to the nodes of the measured velocity field, thereby eliminating the need for measurement interpolation during this step and significantly reducing the computational cost of the algorithm relative to previous approaches. The method is validated by using numerically simulated flow past a stationary, two-dimensional bluff body and a computational model of a three-dimensional, self-propelled anguilliform swimmer to study the effects of spatial and temporal resolution, domain size, signal-to-noise ratio and out-of-plane effects. Particle image velocimetry measurements of a freely swimming jellyfish medusa and a freely swimming lamprey are analyzed using the method to demonstrate the efficacy of the approach when applied to empirical data. PMID:24115059
Patino, Eduardo
1996-01-01
A field experiment was conducted at the Levee 4 canal site below control structure G-88 in the Everglades agricultural area in northwestern Broward County, Florida, to study the relation of acoustic attenuation to suspended-solids concentrations. Acoustic velocity meter and temperature data were obtained with concurrent water samples analyzed for suspended-solids concentrations. Two separate acoustic velocity meter frequencies were used, 200 and 500 kilohertz, to determine the sensitivity of acoustic attenuation to frequency for the measured suspended-solids concentration range. Suspended-solids concentrations for water samples collected at the Levee 4 canal site from July 1993 to September 1994 ranged from 22 to 1,058 milligrams per liter, and organic content ranged from about 30 to 93 percent. Regression analyses showed that attenuation data from the acoustic velocity meter (automatic gain control) and temperature data alone do not provide enough information to adequately describe the concentrations of suspended solids. However, if velocity is also included as one of the independent variables in the regression model, a satisfactory correlation can be obtained. Thus, it is feasible to use acoustic velocity meter instrumentation to estimate suspended-solids concentrations in streams, even when suspended solids are primarily composed of organic material. Using the most comprehensive data set available for the study (500 kiloherz data), the best fit regression model produces a standard error of 69.7 milligrams per liter, with actual errors ranging from 2 to 128 milligrams per liter. Both acoustic velocity meter transmission frequencies of 200 and 500 hilohertz produced similar results, suggesting that transducers of either frequency could be used to collect attenuation data at the study site. Results indicate that calibration will be required for each acoustic velocity meter system to the unique suspended-solids regime existing at each site. More robust solutions may
NASA Astrophysics Data System (ADS)
Wirz, V.; Gruber, S.; Gubler, S.; Purves, R. S.
2014-02-01
Knowledge of processes and factors affecting slope instability is essential for detecting and monitoring potentially hazardous slopes. Knowing the timing of acceleration or deceleration of slope movements can help to identify important controls and hence to increase our process understanding. For this methods to derive reliable velocity estimations are important. The aim of this study was to develop and test a method to derive velocities based on noisy GPS data of various movement patterns and variable signal-to-noise-ratio (SNR). Derived velocities represent reliable average velocities representative for a given period. The applied smoothing windows directly depends on the SNR of the data, which is modeled using Monte Carlo simulation. Hence, all obtained velocities have a SNR above a predefined threshold and for each velocity period the SNR is known, which helps to interpret the temporal variability. In sensitivity tests with synthetic time-series the method was compared to established methods to derive velocities based on GPS positions, including spline and Kernel regression smoothing. Those sensitivity tests clearly demonstrated that methods are required that adopt the time window to the underlying error of the position data. The presented method performs well, even for a high noise levels and variable SNR. Different methods were further applied to investigate the inter-annual variability of permafrost slope movements based on daily GPS- and inclinometer data. In the framework of the new method, we further analyzed the error caused by a rotation of the GPS mast (hmast = 1.5 m). If the tilting is higher than its uncertainty, the rotational movement can be separated and the direction of movement became more uniform. At one GPS station, more than 12% of the measured displacement at the antenna was caused by the rotation of the station.
Feng, Feng; Kepler, Thomas B
2015-01-01
Surface plasmon resonance (SPR) has previously been employed to measure the active concentration of analyte in addition to the kinetic rate constants in molecular binding reactions. Those approaches, however, have a few restrictions. In this work, a Bayesian approach is developed to determine both active concentration and affinity constants using SPR technology. With the appropriate prior probabilities on the parameters and a derived likelihood function, a Markov Chain Monte Carlo (MCMC) algorithm is applied to compute the posterior probability densities of both the active concentration and kinetic rate constants based on the collected SPR data. Compared with previous approaches, ours exploits information from the duration of the process in its entirety, including both association and dissociation phases, under partial mass transport conditions; do not depend on calibration data; multiple injections of analyte at varying flow rates are not necessary. Finally the method is validated by analyzing both simulated and experimental datasets. A software package implementing our approach is developed with a user-friendly interface and made freely available. PMID:26098764
MIDAS robust trend estimator for accurate GPS station velocities without step detection
NASA Astrophysics Data System (ADS)
Blewitt, Geoffrey; Kreemer, Corné; Hammond, William C.; Gazeaux, Julien
2016-03-01
Automatic estimation of velocities from GPS coordinate time series is becoming required to cope with the exponentially increasing flood of available data, but problems detectable to the human eye are often overlooked. This motivates us to find an automatic and accurate estimator of trend that is resistant to common problems such as step discontinuities, outliers, seasonality, skewness, and heteroscedasticity. Developed here, Median Interannual Difference Adjusted for Skewness (MIDAS) is a variant of the Theil-Sen median trend estimator, for which the ordinary version is the median of slopes vij = (xj-xi)/(tj-ti) computed between all data pairs i > j. For normally distributed data, Theil-Sen and least squares trend estimates are statistically identical, but unlike least squares, Theil-Sen is resistant to undetected data problems. To mitigate both seasonality and step discontinuities, MIDAS selects data pairs separated by 1 year. This condition is relaxed for time series with gaps so that all data are used. Slopes from data pairs spanning a step function produce one-sided outliers that can bias the median. To reduce bias, MIDAS removes outliers and recomputes the median. MIDAS also computes a robust and realistic estimate of trend uncertainty. Statistical tests using GPS data in the rigid North American plate interior show ±0.23 mm/yr root-mean-square (RMS) accuracy in horizontal velocity. In blind tests using synthetic data, MIDAS velocities have an RMS accuracy of ±0.33 mm/yr horizontal, ±1.1 mm/yr up, with a 5th percentile range smaller than all 20 automatic estimators tested. Considering its general nature, MIDAS has the potential for broader application in the geosciences.
MIDAS robust trend estimator for accurate GPS station velocities without step detection
Kreemer, Corné; Hammond, William C.; Gazeaux, Julien
2016-01-01
Abstract Automatic estimation of velocities from GPS coordinate time series is becoming required to cope with the exponentially increasing flood of available data, but problems detectable to the human eye are often overlooked. This motivates us to find an automatic and accurate estimator of trend that is resistant to common problems such as step discontinuities, outliers, seasonality, skewness, and heteroscedasticity. Developed here, Median Interannual Difference Adjusted for Skewness (MIDAS) is a variant of the Theil‐Sen median trend estimator, for which the ordinary version is the median of slopes vij = (xj–xi)/(tj–ti) computed between all data pairs i > j. For normally distributed data, Theil‐Sen and least squares trend estimates are statistically identical, but unlike least squares, Theil‐Sen is resistant to undetected data problems. To mitigate both seasonality and step discontinuities, MIDAS selects data pairs separated by 1 year. This condition is relaxed for time series with gaps so that all data are used. Slopes from data pairs spanning a step function produce one‐sided outliers that can bias the median. To reduce bias, MIDAS removes outliers and recomputes the median. MIDAS also computes a robust and realistic estimate of trend uncertainty. Statistical tests using GPS data in the rigid North American plate interior show ±0.23 mm/yr root‐mean‐square (RMS) accuracy in horizontal velocity. In blind tests using synthetic data, MIDAS velocities have an RMS accuracy of ±0.33 mm/yr horizontal, ±1.1 mm/yr up, with a 5th percentile range smaller than all 20 automatic estimators tested. Considering its general nature, MIDAS has the potential for broader application in the geosciences. PMID:27668140
MIDAS robust trend estimator for accurate GPS station velocities without step detection
Kreemer, Corné; Hammond, William C.; Gazeaux, Julien
2016-01-01
Abstract Automatic estimation of velocities from GPS coordinate time series is becoming required to cope with the exponentially increasing flood of available data, but problems detectable to the human eye are often overlooked. This motivates us to find an automatic and accurate estimator of trend that is resistant to common problems such as step discontinuities, outliers, seasonality, skewness, and heteroscedasticity. Developed here, Median Interannual Difference Adjusted for Skewness (MIDAS) is a variant of the Theil‐Sen median trend estimator, for which the ordinary version is the median of slopes vij = (xj–xi)/(tj–ti) computed between all data pairs i > j. For normally distributed data, Theil‐Sen and least squares trend estimates are statistically identical, but unlike least squares, Theil‐Sen is resistant to undetected data problems. To mitigate both seasonality and step discontinuities, MIDAS selects data pairs separated by 1 year. This condition is relaxed for time series with gaps so that all data are used. Slopes from data pairs spanning a step function produce one‐sided outliers that can bias the median. To reduce bias, MIDAS removes outliers and recomputes the median. MIDAS also computes a robust and realistic estimate of trend uncertainty. Statistical tests using GPS data in the rigid North American plate interior show ±0.23 mm/yr root‐mean‐square (RMS) accuracy in horizontal velocity. In blind tests using synthetic data, MIDAS velocities have an RMS accuracy of ±0.33 mm/yr horizontal, ±1.1 mm/yr up, with a 5th percentile range smaller than all 20 automatic estimators tested. Considering its general nature, MIDAS has the potential for broader application in the geosciences.
Estimating unbiased horizontal velocity components from ST/MST radar measurements: A case study
NASA Technical Reports Server (NTRS)
Clark, W. L.; Green, J. L.; Warnock, J. M.
1983-01-01
In this paper a self-editing quick look procedure is presented for use at the Sunset radar. It is used for determining relatively unbiased hourly estimates of the u and v components of the wind. The technique presented here should be applicable to all height ranges, though only ST results are presented here. The vertical wind component, w, may be measured directly by pointing the radar beam straight up. The east and west components of the wind, u and v, however, must be estimated by projecting to the horizontal plane the radial velocity, vr, actually observed by pointing the radar suitably off zenith.
NASA Astrophysics Data System (ADS)
Graf, S.; Craiem, D.; Barra, J. G.; Armentano, R. L.
2011-12-01
Increased arterial stiffness is associated with an increased risk of cardiovascular events. Estimation of arterial stiffness using local pulse wave velocity (PWV) promises to be very useful for noninvasive diagnosis of arteriosclerosis. In this work we estimated in an instrumented sheep, the local aortic pulse wave velocity using two sonomicrometry diameter sensors (separated 7.5 cm) according to the transit time method (PWVTT) with a sampling rate of 4 KHz. We simultaneously measured aortic pressure in order to determine from pressure-diameter loops (PWVPDLoop), the "true" local aortic pulse wave velocity. A pneumatic cuff occluder was implanted in the aorta in order to compare both methods under a wide range of pressure levels. Mean pressure values ranged from 47 to 101 mmHg and mean proximal diameter values from 12.5. to 15.2 mm. There were no significant differences between PWVTT and PWVPDLoop values (451±43 vs. 447±48 cm/s, p = ns, paired t-test). Both methods correlated significantly (R = 0.81, p<0.05). The mean difference between both methods was only -4±29 cm/s, whereas the range of the limits of agreement (mean ± 2 standard deviation) was -61 to +53 cm/s, showing no trend. In conclusion, the diameter waveforms transit time method was found to allow an accurate and precise estimation of the local aortic PWV.
Methodology to estimate the relative pressure field from noisy experimental velocity data
NASA Astrophysics Data System (ADS)
Bolin, C. D.; Raguin, L. G.
2008-11-01
The determination of intravascular pressure fields is important to the characterization of cardiovascular pathology. We present a two-stage method that solves the inverse problem of estimating the relative pressure field from noisy velocity fields measured by phase contrast magnetic resonance imaging (PC-MRI) on an irregular domain with limited spatial resolution, and includes a filter for the experimental noise. For the pressure calculation, the Poisson pressure equation is solved by embedding the irregular flow domain into a regular domain. To lessen the propagation of the noise inherent to the velocity measurements, three filters - a median filter and two physics-based filters - are evaluated using a 2-D Couette flow. The two physics-based filters outperform the median filter for the estimation of the relative pressure field for realistic signal-to-noise ratios (SNR = 5 to 30). The most accurate pressure field results from a filter that applies in a least-squares sense three constraints simultaneously: consistency between measured and filtered velocity fields, divergence-free and additional smoothness conditions. This filter leads to a 5-fold gain in accuracy for the estimated relative pressure field compared to without noise filtering, in conditions consistent with PC-MRI of the carotid artery: SNR = 5, 20 x 20 discretized flow domain (25 X 25 computational domain).
Estimation of unsteady lift on a pitching airfoil from wake velocity surveys
NASA Technical Reports Server (NTRS)
Zaman, K. B. M. Q.; Panda, J.; Rumsey, C. L.
1993-01-01
The results of a joint experimental and computational study on the flowfield over a periodically pitched NACA0012 airfoil, and the resultant lift variation, are reported in this paper. The lift variation over a cycle of oscillation, and hence the lift hysteresis loop, is estimated from the velocity distribution in the wake measured or computed for successive phases of the cycle. Experimentally, the estimated lift hysteresis loops are compared with available data from the literature as well as with limited force balance measurements. Computationally, the estimated lift variations are compared with the corresponding variation obtained from the surface pressure distribution. Four analytical formulations for the lift estimation from wake surveys are considered and relative successes of the four are discussed.
A simple method to estimate threshold friction velocity of wind erosion in the field
NASA Astrophysics Data System (ADS)
Li, Junran; Okin, Gregory S.; Herrick, Jeffrey E.; Belnap, Jayne; Munson, Seth M.; Miller, Mark E.
2010-05-01
This study provides a fast and easy-to-apply method to estimate threshold friction velocity (TFV) of wind erosion in the field. Wind tunnel experiments and a variety of ground measurements including air gun, pocket penetrometer, torvane, and roughness chain were conducted in Moab, Utah and cross-validated in the Mojave Desert, California. Patterns between TFV and ground measurements were examined to identify the optimum method for estimating TFV. The results show that TFVs were best predicted using the air gun and penetrometer measurements in the Moab sites. This empirical method, however, systematically underestimated TFVs in the Mojave Desert sites. Further analysis showed that TFVs in the Mojave sites can be satisfactorily estimated with a correction for rock cover, which is presumably the main cause of the underestimation of TFVs. The proposed method may be also applied to estimate TFVs in environments where other non-erodible elements such as postharvest residuals are found.
Xu, Tiantian; Bashford, Gregory
2013-05-01
We have previously investigated the change of apparent lateral speckle size caused by the direction and spatial rate of scanner A-line acquisition (scan velocity). An algorithm which measures the lateral component of blood flow velocity was developed based on the increase in speckle size resulting from relative motion between moving scatterers and the scan velocity. In this paper, the change of the apparent dominant angle of the speckle pattern in a straight vessel was investigated and a new method of two-dimensional blood flow velocity estimation is introduced. Different scan velocities were used for data acquisition from blood flow traveling at an angle relative to the ultrasound beam. The apparent angle of the speckle pattern changes with different scan velocities because of misregistration between the ultrasound beam and scatterers. The apparent angle of the speckle pattern was resolved by line-to-line cross-correlation in the fast-time (axial) direction on a region-of-interest (ROI) in each blood flow image and used to spatially align the ROI. The resulting lateral speckle size within the aligned ROI was calculated. The lateral component of the blood flow is shown to be closest to the scan velocity which gives the maximum speckle size and the apparent angle of speckle pattern collected by this scan velocity is the best estimate for the actual angle of blood flow. These two components produce two-dimensional blood flow velocity estimations. This method was studied through both computer simulation and experiments with a blood flow phantom. Nine scan velocities were used to collect blood flow data with velocities ranging from 33 to 98 cm/s and four beam-to-flow angles. In simulated plug blood flow, the mean bias of angle estimation is below 2% with an average standard deviation of 3.6%. In simulated parabolic blood flow, the angle of blood flow is overestimated because of speckle decorrelation caused by flow gradients and the estimation bias increases with
Schumacher, Robin; Wahl, S. Aljoscha
2015-01-01
The design of microbial production processes relies on rational choices for metabolic engineering of the production host and the process conditions. These require a systematic and quantitative understanding of cellular regulation. Therefore, a novel method for dynamic flux identification using quantitative metabolomics and 13C labeling to identify piecewise-affine (PWA) flux functions has been described recently. Obtaining flux estimates nevertheless still required frequent manual reinitalization to obtain a good reproduction of the experimental data and, moreover, did not optimize on all observables simultaneously (metabolites and isotopomer concentrations). In our contribution we focus on measures to achieve faster and robust dynamic flux estimation which leads to a high dimensional parameter estimation problem. Specifically, we address the following challenges within the PWA problem formulation: (1) Fast selection of sufficient domains for the PWA flux functions, (2) Control of over-fitting in the concentration space using shape-prescriptive modeling and (3) robust and efficient implementation of the parameter estimation using the hybrid implicit filtering algorithm. With the improvements we significantly speed up the convergence by efficiently exploiting that the optimization problem is partly linear. This allows application to larger-scale metabolic networks and demonstrates that the proposed approach is not purely theoretical, but also applicable in practice. PMID:26690237
Improved Pulse Wave Velocity Estimation Using an Arterial Tube-Load Model
Gao, Mingwu; Zhang, Guanqun; Olivier, N. Bari; Mukkamala, Ramakrishna
2015-01-01
Pulse wave velocity (PWV) is the most important index of arterial stiffness. It is conventionally estimated by non-invasively measuring central and peripheral blood pressure (BP) and/or velocity (BV) waveforms and then detecting the foot-to-foot time delay between the waveforms wherein wave reflection is presumed absent. We developed techniques for improved estimation of PWV from the same waveforms. The techniques effectively estimate PWV from the entire waveforms, rather than just their feet, by mathematically eliminating the reflected wave via an arterial tube-load model. In this way, the techniques may be more robust to artifact while revealing the true PWV in absence of wave reflection. We applied the techniques to estimate aortic PWV from simultaneously and sequentially measured central and peripheral BP waveforms and simultaneously measured central BV and peripheral BP waveforms from 17 anesthetized animals during diverse interventions that perturbed BP widely. Since BP is the major acute determinant of aortic PWV, especially under anesthesia wherein vasomotor tone changes are minimal, we evaluated the techniques in terms of the ability of their PWV estimates to track the acute BP changes in each subject. Overall, the PWV estimates of the techniques tracked the BP changes better than those of the conventional technique (e.g., diastolic BP root-mean-squared-errors of 3.4 vs. 5.2 mmHg for the simultaneous BP waveforms and 7.0 vs. 12.2 mmHg for the BV and BP waveforms (p < 0.02)). With further testing, the arterial tube-load model-based PWV estimation techniques may afford more accurate arterial stiffness monitoring in hypertensive and other patients. PMID:24263016
Shear velocity estimates on the inner shelf off Grays Harbor, Washington, USA
Sherwood, C.R.; Lacy, J.R.; Voulgaris, G.
2006-01-01
Shear velocity was estimated from current measurements near the bottom off Grays Harbor, Washington between May 4 and June 6, 2001 under mostly wave-dominated conditions. A downward-looking pulse-coherent acoustic Doppler profiler (PCADP) and two acoustic-Doppler velocimeters (field version; ADVFs) were deployed on a tripod at 9-m water depth. Measurements from these instruments were used to estimate shear velocity with (1) a modified eddy-correlation (EC) technique, (2) the log-profile (LP) method, and (3) a dissipation-rate method. Although values produced by the three methods agreed reasonably well (within their broad ranges of uncertainty), there were important systematic differences. Estimates from the EC method were generally lowest, followed by those from the inertial-dissipation method. The LP method produced the highest values and the greatest scatter. We show that these results are consistent with boundary-layer theory when sediment-induced stratification is present. The EC method provides the most fundamental estimate of kinematic stress near the bottom, and stratification causes the LP method to overestimate bottom stress. These results remind us that the methods are not equivalent and that comparison among sites and with models should be made carefully. ?? 2006 Elsevier Ltd. All rights reserved.
Hershey, R.L.; Acheampong, S.Y.
1997-06-01
Geochemical and isotopic data from groundwater sampling locations can be used to estimate groundwater flow velocities for independent comparison to velocities calculated by other methods. The objective of this study was to calculate groundwater flow velocities using geochemistry and environmental isotopes from the southern end of Yucca Flat to the Amargosa Desert, considering mixing of different groundwater inputs from sources each and southeast of the Nevada Test Site (NTS). The approach used to accomplish the objective of this study consisted of five steps: (1) reviewing and selecting locations where carbon isotopic groundwater analyses, reliable ionic analysis, and well completion information are available; (2) calculating chemical speciation with the computer code WATEQ4F (Ball and Nordstrom, 1991) to determine the saturation state of mineral phases for each ground water location; (3) grouping wells into reasonable flowpaths and mixing scenarios from different groundwater sources; (4) using the computer code NETPATH (Plummer et al., 1991) to simulate mixing and the possible chemical reactions along the flowpath, and to calculate the changes in carbon-13/carbon-12 isotopic ratios ({delta}{sup 13}C) as a result of these reactions; and (5) using carbon-14 ({sup 14}C) data to calculate velocity.
Velocity estimation algorithms for audio-haptic simulations involving stick-slip.
Sinclair, Stephen; Wanderley, Marcelo M; Hayward, Vincent
2014-01-01
With real-time models of friction that take velocity as input, accuracy depends in great part on adequately estimating velocity from position measurements. This process can be sensitive to noise, especially at high sampling rates. In audio-haptic acoustic simulations, often characterized by friction-induced, relaxation-type stick-slip oscillations, this gives a gritty, dry haptic feel and a raspy, unnatural sound. Numerous techniques have been proposed, but each depend on tuning parameters so that they may offer a good trade-off between delay and noise rejection. In an effort to compare fairly, each of thirteen methods considered in the present study was automatically optimized and evaluated; finally a subset of these were compared subjectively. Results suggest that no one method is ideal for all gain levels, though the best general performance was found by using a sliding-mode differentiator as input to a Kalman integrator. An additional conclusion is that estimators do not approach the quality available in physical velocity transduction, and therefore such sensors should be considered in haptic device design.
Uncertainty estimation of the velocity model for the TrigNet GPS network
NASA Astrophysics Data System (ADS)
Hackl, Matthias; Malservisi, Rocco; Hugentobler, Urs; Wonnacott, Richard
2010-05-01
Satellite based geodetic techniques - above all GPS - provide an outstanding tool to measure crustal motions. They are widely used to derive geodetic velocity models that are applied in geodynamics to determine rotations of tectonic blocks, to localize active geological features, and to estimate rheological properties of the crust and the underlying asthenosphere. However, it is not a trivial task to derive GPS velocities and their uncertainties from positioning time series. In general time series are assumed to be represented by linear models (sometimes offsets, annual, and semi-annual signals are included) and noise. It has been shown that models accounting only for white noise tend to underestimate the uncertainties of rates derived from long time series and that different colored noise components (flicker noise, random walk, etc.) need to be considered. However, a thorough error analysis including power spectra analyses and maximum likelihood estimates is quite demanding and are usually not carried out for every site, but the uncertainties are scaled by latitude dependent factors. Analyses of the South Africa continuous GPS network TrigNet indicate that the scaled uncertainties overestimate the velocity errors. So we applied a method similar to the Allan Variance that is commonly used in the estimation of clock uncertainties and is able to account for time dependent probability density functions (colored noise) to the TrigNet time series. Finally, we compared these estimates to the results obtained by spectral analyses using CATS. Comparisons with synthetic data show that the noise can be represented quite well by a power law model in combination with a seasonal signal in agreement with previous studies.
Xu, Da; Ryan, Kathy L; Rickards, Caroline A; Zhang, Guanqun; Convertino, Victor A; Mukkamala, Ramakrishna
2010-01-01
Pulse wave velocity (PWV) is a marker of arterial stiffness and may permit continuous, non-invasive, and cuff-less monitoring of blood pressure. Here, robust PWV estimation was sought by application of system identification to proximal and distal arterial waveforms. In this approach, the system that optimally couples the proximal waveform to the distal waveform is identified, and the time delay of this system is then used to calculate PWV. To demonstrate proof-of-concept, a standard identification technique was applied to non-invasive impedance cardiography and peripheral arterial blood pressure waveforms from six humans subjected to progressive reductions in central blood volume induced by lower body negative pressure. This technique estimated diastolic pressure with an overall root-mean-squared-error of 5.2 mmHg. For comparison, the conventional detection method for estimating PWV yielded a corresponding error of 8.3 mmHg. PMID:21097042
The Event Detection and the Apparent Velocity Estimation Based on Computer Vision
NASA Astrophysics Data System (ADS)
Shimojo, M.
2012-08-01
The high spatial and time resolution data obtained by the telescopes aboard Hinode revealed the new interesting dynamics in solar atmosphere. In order to detect such events and estimate the velocity of dynamics automatically, we examined the estimation methods of the optical flow based on the OpenCV that is the computer vision library. We applied the methods to the prominence eruption observed by NoRH, and the polar X-ray jet observed by XRT. As a result, it is clear that the methods work well for solar images if the images are optimized for the methods. It indicates that the optical flow estimation methods in the OpenCV library are very useful to analyze the solar phenomena.
Estimation of Rotational Velocity of Baseball Using High-Speed Camera Movies
NASA Astrophysics Data System (ADS)
Inoue, Takuya; Uematsu, Yuko; Saito, Hideo
Movies can be used to analyze a player's performance and improve his/her skills. In the case of baseball, the pitching is recorded by using a high-speed camera, and the recorded images are used to improve the pitching skills of the players. In this paper, we present a method for estimating of the rotational velocity of a baseball on the basis of movies recorded by high-speed cameras. Unlike in the previous methods, we consider the original seam pattern of the ball seen in the input movie and identify the corresponding image from a database of images by adopting the parametric eigenspace method. These database images are CG Images. The ball's posture can be determined on the basis of the rotational parameters. In the proposed method, the symmetric property of the ball is also taken into consideration, and the time continuity is used to determine the ball's posture. In the experiments, we use the proposed method to estimate the rotational velocity of a baseball on the basis of real movies and movies consisting of CG images of the baseball. The results of both the experiments prove that our method can be used to estimate the ball's rotation accurately.
Li, You; Mo, Lei; Chen, Qi
2015-07-01
To successfully intercept/avoid a moving object, human brain needs to precisely estimate the time-to-collision (TTC) of the object. In real life, time estimation is determined conjointly by the velocity and the distance of a moving object. However, surprisingly little is known concerning whether and how the velocity and the distance dimensions contribute differentially to time estimation. In this fMRI study, we demonstrated that variations of velocity evoked substantially different behavioral and neural responses than distance during self-initiated TTC judgments. Behaviorally, the velocity dimension induced a stronger time dilation effect than the distance dimension that participants' responses were significantly more delayed by increasing velocity than by decreasing distance, even with the theoretical TTC being equated between the two conditions. Neurally, activity in the dorsal fronto-parietal TTC network was parametrically modulated by variations in TTC irrespective of whether the variations in TTC were caused by velocity or distance. Importantly, even with spatial distance being equated, increasing velocity induced illusory perception of longer spatial trajectory in early visual cortex. Moreover, as velocity increased, the early visual cortex showed enhanced connectivity with the TTC network. Our results thus implied that with increasing velocity, TTC judgments depended increasingly on the velocity-induced illusory distance information from early visual cortex and was eventually tampered.
Kashif, Faisal M.; Verghese, George C.; Novak, Vera; Czosnyka, Marek; Heldt, Thomas
2014-01-01
Intracranial pressure (ICP) is affected in many neurological conditions. Clinical measurement of pressure on the brain currently requires placing a probe in the cerebrospinal fluid compartment, the brain tissue, or other intracranial space. This invasiveness limits the measurement to critically ill patients. As ICP is also clinically important in conditions ranging from brain tumors and hydrocephalus to concussions, noninvasive determination of ICP would be desirable. Our model-based approach to continuous estimation and tracking of ICP uses routinely obtainable time-synchronized, noninvasive (or minimally invasive) measurements of peripheral arterial blood pressure and blood flow velocity in the middle cerebral artery (MCA), both at intra-heartbeat resolution. A physiological model of cerebrovascular dynamics provides mathematical constraints that relate the measured waveforms to ICP. Our algorithm produced patient-specific ICP estimates with no calibration or training. Using 35 hours of data from 37 patients with traumatic brain injury, we generated ICP estimates on 2,665 non-overlapping 60-beat data windows. Referenced against concurrently recorded invasive parenchymal ICP that varied over 100 mmHg across all records, our estimates achieved a mean error (bias) of 1.6 mmHg and standard deviation of error (SDE) of 7.6 mmHg. For the 1,673 data windows over 22 hours in which blood flow velocity recordings were available from both the left and right MCA, averaging the resulting bilateral ICP estimates reduced the bias to 1.5 mmHg and SDE to 5.9 mmHg. This accuracy is already comparable to that of some invasive ICP measurement methods in current clinical use. PMID:22496546
Benchmarking passive seismic methods of estimating the depth of velocity interfaces down to ~300 m
NASA Astrophysics Data System (ADS)
Czarnota, Karol; Gorbatov, Alexei
2016-04-01
In shallow passive seismology it is generally accepted that the spatial autocorrelation (SPAC) method is more robust than the horizontal-over-vertical spectral ratio (HVSR) method at resolving the depth to surface-wave velocity (Vs) interfaces. Here we present results of a field test of these two methods over ten drill sites in western Victoria, Australia. The target interface is the base of Cenozoic unconsolidated to semi-consolidated clastic and/or carbonate sediments of the Murray Basin, which overlie Paleozoic crystalline rocks. Depths of this interface intersected in drill holes are between ~27 m and ~300 m. Seismometers were deployed in a three-arm spiral array, with a radius of 250 m, consisting of 13 Trillium Compact 120 s broadband instruments. Data were acquired at each site for 7-21 hours. The Vs architecture beneath each site was determined through nonlinear inversion of HVSR and SPAC data using the neighbourhood algorithm, implemented in the geopsy modelling package (Wathelet, 2005, GRL v35). The HVSR technique yielded depth estimates of the target interface (Vs > 1000 m/s) generally within ±20% error. Successful estimates were even obtained at a site with an inverted velocity profile, where Quaternary basalts overlie Neogene sediments which in turn overlie the target basement. Half of the SPAC estimates showed significantly higher errors than were obtained using HVSR. Joint inversion provided the most reliable estimates but was unstable at three sites. We attribute the surprising success of HVSR over SPAC to a low content of transient signals within the seismic record caused by low levels of anthropogenic noise at the benchmark sites. At a few sites SPAC waveform curves showed clear overtones suggesting that more reliable SPAC estimates may be obtained utilizing a multi-modal inversion. Nevertheless, our study indicates that reliable basin thickness estimates in the Australian conditions tested can be obtained utilizing HVSR data from a single
NASA Astrophysics Data System (ADS)
Yeom, Hong Gi; Sic Kim, June; Chung, Chun Kee
2013-04-01
Objective. Studies on the non-invasive brain-machine interface that controls prosthetic devices via movement intentions are at their very early stages. Here, we aimed to estimate three-dimensional arm movements using magnetoencephalography (MEG) signals with high accuracy. Approach. Whole-head MEG signals were acquired during three-dimensional reaching movements (center-out paradigm). For movement decoding, we selected 68 MEG channels in motor-related areas, which were band-pass filtered using four subfrequency bands (0.5-8, 9-22, 25-40 and 57-97 Hz). After the filtering, the signals were resampled, and 11 data points preceding the current data point were used as features for estimating velocity. Multiple linear regressions were used to estimate movement velocities. Movement trajectories were calculated by integrating estimated velocities. We evaluated our results by calculating correlation coefficients (r) between real and estimated velocities. Main results. Movement velocities could be estimated from the low-frequency MEG signals (0.5-8 Hz) with significant and considerably high accuracy (p <0.001, mean r > 0.7). We also showed that preceding (60-140 ms) MEG signals are important to estimate current movement velocities and the intervals of brain signals of 200-300 ms are sufficient for movement estimation. Significance. These results imply that disabled people will be able to control prosthetic devices without surgery in the near future.
NASA Astrophysics Data System (ADS)
Lorenzo, J. M.; Goff, D.; Hayashi, K.
2015-12-01
Unconsolidated Holocene deltaic sediments comprise levee foundation soils in New Orleans, USA. Whereas geotechnical tests at point locations are indispensable for evaluating soil stability, the highly variable sedimentary facies of the Mississippi delta create difficulties to predict soil conditions between test locations. Combined electrical resistivity and seismic shear wave studies, calibrated to geotechnical data, may provide an efficient methodology to predict soil types between geotechnical sites at shallow depths (0- 10 m). The London Avenue Canal levee flank of New Orleans, which failed in the aftermath of Hurricane Katrina, 2005, presents a suitable site in which to pioneer these geophysical relationships. Preliminary cross-plots show electrically resistive, high-shear-wave velocity areas interpreted as low-permeability, resistive silt. In brackish coastal environments, low-resistivity and low-shear-wave-velocity areas may indicate both saturated, unconsolidated sands and low-rigidity clays. Via a polynomial approximation, soil sub-types of sand, silt and clay can be estimated by a cross-plot of S-wave velocity and resistivity. We confirm that existent boring log data fit reasonably well with the polynomial approximation where 2/3 of soil samples fall within their respective bounds—this approach represents a new classification system that could be used for other mid-latitude, fine-grained deltas.
[Estimates of velocity of the travelling wave in the high-range cochlea of the dolphin].
Popov, V V; Supin, A Ia
2014-07-01
Auditory brainstem responses (ABR) to sound pulses of precisely defined spectrum band of 0.5 oct (from 11.2-16 to 90-128 kHz) were recorded in bottlenose dolphins Tursiops truncatus. At equal stimulus levels, ABR amplitude depended on the stimulus spectrum band: the higher the frequency, the higher the amplitude. ABR waveform little depended on the stimulus spectrum band, however ABR latency did depend: the higher the frequency, the shorter the latency. The latency difference between responses to the lowest-frequency (11.2-16 kHz) and the highest-frequency (90-129 kHz) stimuli was up to 0.3 ms. This latency difference was attributed to the time of the wave travelling along the basilar membrane. Therefore, the data were used to compute the travelling-wave velocity. The obtained estimates were: 38.2 oct/ms at the proximal (high-frequ- ency) end of the basilar membrane to 2.8 oct/ms at the distal (low-frequency) end. Comparison of the travelling-wave velocities in humans and dolphins shows that the travelling-wave velocity is linked to the characteristic frequency, not to the place in the cochlea.
[Estimates of velocity of the travelling wave in the high-range cochlea of the dolphin].
Popov, V V; Supin, A Ia
2014-07-01
Auditory brainstem responses (ABR) to sound pulses of precisely defined spectrum band of 0.5 oct (from 11.2-16 to 90-128 kHz) were recorded in bottlenose dolphins Tursiops truncatus. At equal stimulus levels, ABR amplitude depended on the stimulus spectrum band: the higher the frequency, the higher the amplitude. ABR waveform little depended on the stimulus spectrum band, however ABR latency did depend: the higher the frequency, the shorter the latency. The latency difference between responses to the lowest-frequency (11.2-16 kHz) and the highest-frequency (90-129 kHz) stimuli was up to 0.3 ms. This latency difference was attributed to the time of the wave travelling along the basilar membrane. Therefore, the data were used to compute the travelling-wave velocity. The obtained estimates were: 38.2 oct/ms at the proximal (high-frequ- ency) end of the basilar membrane to 2.8 oct/ms at the distal (low-frequency) end. Comparison of the travelling-wave velocities in humans and dolphins shows that the travelling-wave velocity is linked to the characteristic frequency, not to the place in the cochlea. PMID:25669111
Bjerklie, D.M.
2007-01-01
A method to estimate the bankfull velocity and discharge in rivers that uses the morphological variables of the river channel, including bankfull width, channel slope, and meander length was developed and tested. Because these variables can be measured remotely from topographic and river alignment information derived from aerial photos and satellite imagery, it is possible that the bankfull state of flow can be estimated for rivers entirely from remotely-sensed information. Defining the bankfull hydraulics of rivers would also provide a reference condition for remote tracking of dynamic variables including width, stage, and slope, and for quantifying relative change in flow conditions of rivers over large regions. This could provide a more efficient method to inventory and quantify river hydraulic attributes and dynamics.
Estimation of αL, velocity, Kd and confidence limits from tracer injection test data
Broermann, James; Bassett, R.L.; Weeks, Edwin P.; Borgstrom, Mark
1997-01-01
Bromide and boron were used as tracers during an injection experiment conducted at an artificial recharge facility near Stanton, Texas. The Ogallala aquifer at the Stanton site represents a heterogeneous alluvial environment and provides the opportunity to report scale dependent dispersivities at observation distances of 2 to 15 m in this setting. Values of longitudinal dispersivities are compared with other published values. Water samples were collected at selected depths both from piezometers and from fully screened observation wells at radii of 2, 5, 10 and 15 m. An exact analytical solution is used to simulate the concentration breakthrough curves and estimate longitudinal dispersivities and velocity parameters. Greater confidence can be placed on these data because the estimated parameters are error bounded using the bootstrap method. The non-conservative behavior of boron transport in clay rich sections of the aquifer were quantified with distribution coefficients by using bromide as a conservative reference tracer.
Estimation of Venus wind velocities from high-resolution infrared spectra. Ph.D. Thesis
NASA Technical Reports Server (NTRS)
Smith, M. A. H.
1978-01-01
Zonal velocity profiles in the Venus atmosphere above the clouds were estimated from measured asymmetries of HCl and HF infrared absorption lines in high-resolution Fourier interferometer spectra of the planet. These asymmetries are caused by both pressure-induced shifts in the positions of the hydrogen-halide lines perturbed by CO2 and Doppler shifts due to atmospheric motions. Particularly in the case of the HCl 2-0 band, the effects of the two types of line shifts can be easily isolated, making it possible to estimate a profile of average Venus equatorial zonal velocity as a function of pressure in the region roughly 60 to 70 km above the surface of the planet. The mean profiles obtained show strong vertical shear in the Venus zonal winds near the cloud-top level, and both the magnitude and direction of winds at all levels in this region appear to vary greatly with longitude relative to the sub-solar point.
Wacks, Steven; Yazici, Birsen
2014-06-01
In the Part 1 of this two-part study, we present a method of imaging and velocity estimation of ground moving targets using passive synthetic aperture radar. Such a system uses a network of small, mobile receivers that collect scattered waves due to transmitters of opportunity, such as commercial television, radio, and cell phone towers. Therefore, passive imaging systems have significant cost, manufacturing, and stealth advantages over active systems. We describe a novel generalized Radon transform-type forward model and a corresponding filtered-backprojection-type image formation and velocity estimation method. We form a stack of position images over a range of hypothesized velocities, and show that the targets can be reconstructed at the correct position whenever the hypothesized velocity is equal to the true velocity of targets. We then use entropy to determine the most accurate velocity and image pair for each moving target. We present extensive numerical simulations to verify the reconstruction method. Our method does not require a priori knowledge of transmitter locations and transmitted waveforms. It can determine the location and velocity of multiple targets moving at different velocities. Furthermore, it can accommodate arbitrary imaging geometries. In Part 2, we present the resolution analysis and analysis of positioning errors in passive SAR images due to erroneous velocity estimation. PMID:24815619
Wacks, Steven; Yazici, Birsen
2014-06-01
In the Part 1 of this two-part study, we present a method of imaging and velocity estimation of ground moving targets using passive synthetic aperture radar. Such a system uses a network of small, mobile receivers that collect scattered waves due to transmitters of opportunity, such as commercial television, radio, and cell phone towers. Therefore, passive imaging systems have significant cost, manufacturing, and stealth advantages over active systems. We describe a novel generalized Radon transform-type forward model and a corresponding filtered-backprojection-type image formation and velocity estimation method. We form a stack of position images over a range of hypothesized velocities, and show that the targets can be reconstructed at the correct position whenever the hypothesized velocity is equal to the true velocity of targets. We then use entropy to determine the most accurate velocity and image pair for each moving target. We present extensive numerical simulations to verify the reconstruction method. Our method does not require a priori knowledge of transmitter locations and transmitted waveforms. It can determine the location and velocity of multiple targets moving at different velocities. Furthermore, it can accommodate arbitrary imaging geometries. In Part 2, we present the resolution analysis and analysis of positioning errors in passive SAR images due to erroneous velocity estimation.
NASA Astrophysics Data System (ADS)
Zhang, Xiangwen; Xu, Yong; Pan, Ming; Ren, Fenghua
2014-04-01
A sliding-mode observer is designed to estimate the vehicle velocity with the measured vehicle acceleration, the wheel speeds and the braking torques. Based on the Burckhardt tyre model, the extended Kalman filter is designed to estimate the parameters of the Burckhardt model with the estimated vehicle velocity, the measured wheel speeds and the vehicle acceleration. According to the estimated parameters of the Burckhardt tyre model, the tyre/road friction coefficients and the optimal slip ratios are calculated. A vehicle adaptive sliding-mode control (SMC) algorithm is presented with the estimated vehicle velocity, the tyre/road friction coefficients and the optimal slip ratios. And the adjustment method of the sliding-mode gain factors is discussed. Based on the adaptive SMC algorithm, a vehicle's antilock braking system (ABS) control system model is built with the Simulink Toolbox. Under the single-road condition as well as the different road conditions, the performance of the vehicle ABS system is simulated with the vehicle velocity observer, the tyre/road friction coefficient estimator and the adaptive SMC algorithm. The results indicate that the estimated errors of the vehicle velocity and the tyre/road friction coefficients are acceptable and the vehicle ABS adaptive SMC algorithm is effective. So the proposed adaptive SMC algorithm can be used to control the vehicle ABS without the information of the vehicle velocity and the road conditions.
Clark, G
2003-04-28
This report describes a feasibility study. We are interested in calculating the angular and linear velocities of a re-entry vehicle using six acceleration signals from a distributed accelerometer inertial measurement unit (DAIMU). Earlier work showed that angular and linear velocity calculation using classic nonlinear ordinary differential equation (ODE) solvers is not practically feasible, due to mathematical and numerical difficulties. This report demonstrates the theoretical feasibility of using model-based nonlinear state estimation techniques to obtain the angular and linear velocities in this problem. Practical numerical and calibration issues require additional work to resolve. We show that the six accelerometers in the DAIMU are not sufficient to provide observability, so additional measurements of the system states are required (e.g. from a Global Positioning System (GPS) unit). Given the constraint that our system cannot use GPS, we propose using the existing on-board 3-axis magnetometer to measure angular velocity. We further show that the six nonlinear ODE's for the vehicle kinematics can be decoupled into three ODE's in the angular velocity and three ODE's in the linear velocity. This allows us to formulate a three-state Gauss-Markov system model for the angular velocities, using the magnetometer signals in the measurement model. This re-formulated model is observable, allowing us to build an Extended Kalman Filter (EKF) for estimating the angular velocities. Given the angular velocity estimates from the EKF, the three ODE's for the linear velocity become algebraic, and the linear velocity can be calculated by numerical integration. Thus, we do not need direct measurements of the linear velocity to provide observability, and the technique is mathematically feasible. Using a simulation example, we show that the estimator adds value over the numerical ODE solver in the presence of measurement noise. Calculating the velocities in the presence of
Pozzo, M; Merlo, E; Farina, D; Antonutto, G; Merletti, R; Di Prampero, P E
2004-06-01
Muscle-fiber conduction velocity (CV) was estimated from surface electromyographic (EMG) signals during isometric contractions and during short (150-200 ms), explosive, dynamic exercises. Surface EMG signals were recorded with four linear adhesive arrays from the vastus lateralis and medialis muscles of 12 healthy subjects. Isometric contractions were at linearly increasing force from 0% to 100% of the maximum. The dynamic contractions consisted of explosive efforts of the lower limb on a sledge ergometer. For the explosive contractions, muscle-fiber CV was estimated in seven time-windows located along the ascending time interval of the force. There was a significant correlation between CV values during the isometric ramp and explosive contractions (R = 0.75). Moreover, CV estimates increased significantly from (mean +/- SD) 4.32 +/- 0.46 m/s to 4.97 +/- 0.45 m/s during the increasing-force explosive task. It was concluded that CV can be estimated reliably during dynamic tasks involving fast limb movements and that, in these contractions, it may provide important information on motor-unit control properties.
Jet-intracluster medium interaction in Hydra A - I. Estimates of jet velocity from inner knots
NASA Astrophysics Data System (ADS)
Nawaz, M. A.; Wagner, A. Y.; Bicknell, G. V.; Sutherland, R. S.; McNamara, B. R.
2014-10-01
We present the first stage of an investigation of the interactions of the jets in the radio galaxy Hydra A with the intracluster medium. We consider the jet kinetic power, the galaxy and cluster atmosphere and the inner structure of the radio source. Analysing radio observations of the inner lobes of Hydra A by Taylor et al. we confirm the jet power estimates ˜1045 erg s-1 derived by Wise et al. from dynamical analysis of the X-ray cavities. With this result and a model for the galaxy halo, we explore the jet-intracluster medium interactions occurring on a scale of 10 kpc using two-dimensional, axisymmetric, relativistic pure hydrodynamic simulations. A key feature is that we identify the three bright knots in the northern jet as biconical reconfinement shocks, which result when an overpressured jet starts to come into equilibrium with the galactic atmosphere. Through an extensive parameter space study we deduce that the jet velocity is approximately 0.8c at a distance 0.5 kpc from the black hole. The combined constraints of jet power, the observed jet radius profile along the jet and the estimated jet pressure and jet velocity imply a value of the jet density parameter χ ≈ 13 for the northern jet. We show that for a jet β = 0.8 and θ = 42°, an intrinsic asymmetry in the emissivity of the northern and southern jet is required for a consistent brightness ratio ≈7 estimated from the 6-cm Very Large Array image of Hydra A.
NASA Astrophysics Data System (ADS)
Liu, Xiaohan; Schauer, Thomas; Goldack, Arndt; Bleicher, Achim; Schlaich, Mike
2016-09-01
Lightweight footbridges are very elegant but also prone to vibration. By employing active vibration control, smart footbridges could accomplish not only the architectural concept but also the required serviceability and comfort. Inertial sensors such as accelerometers allow the estimation of nodal velocities and displacements. A Kalman filter together with a band-limited multiple Fourier linear combiner (BMFLC) is applied to enable a drift-free estimation of these signals for the quasi-periodic motion under pedestrian excitation without extra information from other kinds of auxiliary sensors. The modal velocities of the structure are determined by using a second Kalman filter with the known applied actuator forces as inputs and the estimated nodal displacement and velocities as measurements. The obtained multi-modal velocities are then used for feedback control. An ultra-lightweight stress-ribbon footbridge built in the Peter-Behrens- Halle at the Technische Universitat Berlin served as the research object. Using two inertial sensors in optimal points we can estimate the dominant modal characteristics of this bridge. Real-time implementation and evaluation results of the proposed estimator will be presented in comparison to signals derived from classical displacement encoders. The real-time estimated modal velocities were applied in a multi-modal velocity feedback vibration control scheme with lightweight pneumatic muscle actuators. Experimental results demonstrate the feasibility of using inertial sensors for active vibration control of lightweight footbridges.
Lucchese, Luca; Leorin, Simone; Cortelazzo, Guido M
2006-10-01
This paper presents a new and effective method for estimating two-dimensional affine transformations and its application to image registration. The method is based on matching polar curves obtained from the radial projections of the image energies, defined as the squared magnitudes of their Fourier transforms. Such matching is formulated as a simple minimization problem whose optimal solution is found with the Levenberg-Marquardt algorithm. The analysis of affine transformations in the frequency domain exploits the well-known property whereby the translational displacement in this domain can be factored out and separately estimated through phase correlation after the four remaining degrees of freedom of the affine warping have been determined. Another important contribution of this paper, emphasized through one example of image mosaicking and one example of remote sensing image registration, consists in showing that affine motion can be accurately estimated by applying our algorithm to the shapes of macrofeatures extracted from the images to register. The excellent performance of the algorithm is also shown through a synthetic example of motion estimation and its comparison with another standard registration technique.
NASA Astrophysics Data System (ADS)
Perozzi, Lorenzo; Gloaguen, Erwan; Rondenay, Stephane; Leite, André; McDowell, Glenn; Wheeler, Robert
2010-05-01
In the mining industry, classic methods to build a grade model for ore deposits are based on kriging or cokriging of grades for targeted minerals measured in drill core in fertile geological units. As the complexity of the geological geometry increases, so does the complexity of grade estimations. For example, in layered mafic or ultramafic intrusions, it is necessary to know the layering geometry in order to perform kriging of grades in the most fertile zones. Without additional information on geological framwork, the definition of fertile zones is a low-precision exercise that requires extensive experience and good ability from the geologist. Recently, thanks to computer and geophysical tool improvements, seismic tomography became very attractive for many application fields. Indeed, this non-intrusive technique allows inferring the mechanical properties of the ground using travel times and amplitude analysis of the transmitted wavelet between two boreholes, hence provide additional information on the nature of the deposit. Commonly used crosshole seismic velocity tomography algorithms estimate 2D slowness models (inverse of velocity) in the plane between the boreholes using the measured direct wave travel times from the transmitter (located in one of the hole) to the receivers (located in the other hole). Furthermore, geophysical borehole logging can be used to constrain seismic tomography between drill holes. Finally, this project aims to estimate grade of economically worth mineral by integrating seismic tomography data with respectively drill core measured grades acquired by Vale Inco for one of their mine sites in operation. In this study, a new type algorithm that combines geostatistical simulation and tomography in the same process (namely stochastic tomography) has been used. The principle of the stochastic tomography is based on the straight ray approximation and use the linear relationship between travel time and slowness to estimate the slowness
Šolínová, Veronika; Mikysková, Hana; Kaiser, Martin Maxmilián; Janeba, Zlatko; Holý, Antonín; Kašička, Václav
2016-01-01
Affinity capillary electrophoresis (ACE) has been applied to estimation of apparent binding constant of complexes of (R,S)-enantiomers of selected acyclic nucleoside phosphonates (ANPs) with chiral selector β-cyclodextrin (βCD) in aqueous alkaline medium. The noncovalent interactions of five pairs of (R,S)-enantiomers of ANPs-based antiviral drugs and their derivatives with βCD were investigated in the background electrolyte (BGE) composed of 35 or 50 mM sodium tetraborate, pH 10.0, and containing variable concentration (0-25 mM) of βCD. The apparent binding constants of the complexes of (R,S)-enantiomers of ANPs with βCD were estimated from the dependence of effective electrophoretic mobilities of (R,S)-enantiomers of ANPs (measured simultaneously by ACE at constant reference temperature 25°C inside the capillary) on the concentration of βCD in the BGE using different nonlinear and linear calculation methodologies. Nonlinear regression analysis provided more precise and accurate values of the binding constants and a higher correlation coefficient as compared to the regression analysis of the three linearized plots of the effective mobility dependence on βCD concentration in the BGE. The complexes of (R,S)-enantiomers of ANPs with βCD have been found to be relatively weak - their apparent binding constants determined by the nonlinear regression analysis were in the range 13.3-46.4 L/mol whereas the values from the linearized plots spanned the interval 12.3-55.2 L/mol. PMID:26426398
Estimate of absolute geostrophic velocity from the density field in the northeastern Pacific Ocean
Coats, D.A.
1981-09-20
A pair of hydrographic sections (35/sup 0/N, 155/sup 0/W) were analyzed to compute absolute velocity by using a variation of the technique by Stommel and Schott (1977). Absolute velocity is determined from an integrated form of the potential vorticity equation by a technique suggested by Davis (1978). This study is the first application of this technique that allows a direct comparison between the uncertainty in estimating a smooth density field and the amount of imbalance in the system of model equations. Because the amount of incompatibility (imbalance) in the system of equations is far smaller than is allowed by the uncertainty in defining the smooth field, the model equation is considered adequate for this set of data. Below 400 m, the nearly constant zonal isopycnal slope indicates that potential vorticity is uniform on isopycnal surfaces. Since the method depends on resolving flow directions from the intersection of isopycnals and surfaces of constant potential vorticity, the absolute velocity is indeterminate in this region. The model equation does, however, constrain the structure of the meridional density field and requires a poleward shift in the latitude which successively deeper isopycnals reach their maximum depth. The fact that this poleward translation can be predicted over several degrees of latitude suggests potential vorticity is uniform over a substantial portion of the North Pacific subtropical gyre. This poleward translation of the density field is an aspect of subtropical density fields, in general, and occurs in conjunction with a translation in the field of geopotential anomaly. It is directly related to the curvature in the deep portion of the beta spiral.
Estimation of vertical migration velocity of (137)Cs in the Mount IDA/Kazdagi, Turkey.
Karadeniz, Özlem; Çakır, Rukiye; Karakurt, Hidayet
2015-08-01
This paper presents the results obtained from a radioecological study carried out in the forest sites of Mount IDA (Kazdagi)/Edremit, Turkey. For 118 soil profiles, the depth distribution of (137)Cs activity was established by fitting the experimental points to an exponential, a gaussian or a log-normal function. The relaxation lengths were in the range of 1.09-16.7 cm with a mean of 5.73 cm, showing a slow transport and a strong retention capacity of (137)Cs even after the 26-y period of Chernobyl accident. From the data for the vertical distribution of (137)Cs in soil profiles, the mean annual migration velocity of (137)Cs was in the range of 0.11-0.62 cm year(-1) with a mean of 0.30 cm year(-1). Statistically significant correlations between the thickness of the humus layer and the mean annual velocity of (137)Cs were found for both coniferous and mixed forest sites. The mean annual velocity of (137)Cs in the forests sites with Pinus nigra var pallasiana was significantly higher than sites with Pinus brutia. External dose-rates from the (137)Cs in forest soils were estimated using a conversion factor used in many studies and comprised with the external dose-rates determined according to the vertical distribution of (137)Cs within the soil depth profiles. It is clearly seen that both levels and spatial distribution patterns of the external dose-rates from (137)Cs were influenced considerably with the vertical migration rate and the vertical distribution of (137)Cs.
Estimation of Fuel Rate on the Galactic Disk from High Velocity Clouds (HVCs) Infall
NASA Astrophysics Data System (ADS)
Sung, Kwang Hyun; Kwak, Kyujin
2016-06-01
Continuous accretion of metal-poor gas can explain the discrepancy between the number of observed G-Dwarfs and the number predicted by the “simple model” of galactic evolution. The maximum accretion rate estimated based upon approaching high velocity clouds (HVCs) can be up to ~0.4 M⊙yr-1 which is comparable with the accretion rate required by many chemical evolution models that is at least ~0.45 M⊙yr-1. However, it is not clear to what extent the exchange of gas between the disk and the cloud can occur when a HVC collides with the galactic disk. Therefore, we examined a series of HVC-Disk collision simulations using the FLASH2.5 hydrodynamics simulation code. Our simulation results show that an HVC will more likely take away substances from the galactic disk rather than adding new material to the disk. We define this as a “negative fuel rate” event. Further outcomes in our study present that the fuel rate, which is defined as how much material is transferred to the galactic disk from the colliding HVC, can change depending on the combination among density, radius and velocity of an approaching HVC as well as the modeled galactic disk.
Dry Deposition Velocity Estimation for the Savannah River Site: Part 1 – Parametric Analysis
Napier, Bruce A.
2012-01-16
Values for the dry deposition velocity of airborne particles were estimated with the GENII Version 2.10 computer code for the Savannah River site using assumptions about surface roughness parameters and particle size and density. Use of the GENII code is recommended by the U.S. Department of Energy for this purpose. Meteorological conditions evaluated include atmospheric stability classes D, E, and F and wind speeds of 0.5, 1.0, 1.5, and 3.0 m/s. Local surface roughness values ranging from 0.03 to 2 meters were evaluated. Particles with mass mean diameters of 1, 5, and 10 microns and densities of 1, 3, and 5 g/cm3 were evaluated.
Yield estimation based on calculated comparisons to particle velocity data recorded at low stress
Rambo, J.
1993-05-01
This paper deals with the problem of optimizing the yield estimation process if some of the material properties are known from geophysical measurements and others are inferred from in-situ dynamic measurements. The material models and 2-D simulations of the event are combined to determine the yield. Other methods of yield determination from peak particle velocity data have mostly been based on comparisons of nearby events in similar media at the Nevada Test Site. These methods are largely empirical and are subject to additional error when a new event has different properties than the population being used for a basis of comparison. The effect of material variations can be examined using Lawrence Livermore National Laboratory's KDYNA computer code. The data from the FLAX event provide an instructive example for simulation.
Yield estimation based on calculated comparisons to particle velocity data recorded at low stress
Rambo, J.
1993-05-01
This paper deals with the problem of optimizing the yield estimation process if some of the material properties are known from geophysical measurements and others are inferred from in-situ dynamic measurements. The material models and 2-D simulations of the event are combined to determine the yield. Other methods of yield determination from peak particle velocity data have mostly been based on comparisons of nearby events in similar media at the Nevada Test Site. These methods are largely empirical and are subject to additional error when a new event has different properties than the population being used for a basis of comparison. The effect of material variations can be examined using Lawrence Livermore National Laboratory`s KDYNA computer code. The data from the FLAX event provide an instructive example for simulation.
NASA Astrophysics Data System (ADS)
Zhu, Tieyuan; Harris, Jerry M.
2015-12-01
We present an iterative joint inversion approach for improving the consistence of estimated P-wave velocity, S-wave velocity and attenuation factor models. This type of inversion scheme links two or more independent inversions using a joint constraint, which is constructed by the cross-gradient function in this paper. The primary advantages of this joint inversion strategy are: avoiding weighting for different datasets in conventional simultaneous joint inversion, flexible for incorporating prior information, and relatively easy to code. We demonstrate the algorithm with two synthetic examples and two field datasets. The inversions for P- and S-wave velocity are based on ray traveltime tomography. The results of the first synthetic example show that the iterative joint inversion take advantages of both P- and S-wave sensitivity to resolve their ambiguities as well as improve structural similarity between P- and S-wave velocity models. In the second synthetic and field examples, joint inversion of P- and S-wave traveltimes results in an improved Vs velocity model that shows better structural correlation with the Vp model. More importantly, the resultant VP/VS ratio map has fewer artifacts and is better correlated for use in geological interpretation than the independent inversions. The second field example illustrates that the flexible joint inversion algorithm using frequency-shift data gives a structurally improved attenuation factor map constrained by a prior VP tomogram.
NASA Astrophysics Data System (ADS)
Sousa, D.; Lee, A.; Parker, O. P.; Pressler, Y.; Guo, S.; Osmanoglu, B.; Schmidt, C.
2012-12-01
Global studies show that Earth's glaciers are losing mass at increasing rates, creating a challenge for communities that rely on them as natural resources. Field observation of glacial environments is limited by cost and inaccessibility. Optical remote sensing is often precluded by cloud cover and seasonal darkness. Synthetic aperture radar (SAR) overcomes these obstacles by using microwave-frequency electromagnetic radiation to provide high resolution information on large spatial scales and in remote, atmospherically obscured environments. SAR is capable of penetrating clouds, operating in darkness, and discriminating between targets with ambiguous spectral signatures. This study evaluated the efficacy of two SAR Earth observation methods on small (< 7 km2) glaciers in rugged topography. The glaciers chosen for this study lie on Isanotski Volcano in Unimak Island, Aleutian Archipelago, USA. The local community on the island, the City of False Pass, relies on glacial melt for drinking water and hydropower. Two methods were used: (1) velocity field estimation based on Repeat Image Feature Tracking (RIFT) and (2) glacial boundary delineation based on interferometric coherence mapping. NASA Uninhabited Aerial Vehicle SAR (UAVSAR) single-polarized power images and JAXA Advanced Land Observing Satellite Phased Array type L-band SAR (ALOS PALSAR) single-look complex images were analyzed over the period 2008-2011. UAVSAR image pairs were coregistered to sub-pixel accuracy and processed with the Coregistration of Optically Sensed Images and Correlation (COSI-Corr) feature tracking module to derive glacial velocity field estimates. Maximum glacier velocities ranged from 28.9 meters/year to 58.3 meters/year. Glacial boundaries were determined from interferometric coherence of ALOS PALSAR data and subsequently refined with masking operations based on terrain slope and segment size. Accuracy was assessed against hand-digitized outlines from high resolution UAVSAR power images
Estimation Of The Average Velocity Of Ship(s) Using Multi Sensor Data
NASA Astrophysics Data System (ADS)
Srinivasa Rao, N.; Ali, M. M.; Rao, M. V.; Ramana, I. V.
IRS_P4 (OCM) and NOAA-AVHRR are ocean sensors. These sensors have variety of applications besides being used for retrieval of ocean parameters like chlorophyll, suspended matter, dissolved organic matter Sea surface temperature (SST) and Identification of Potential Fishing Zones (PFZ). Apart from this an attempt has been made to track the ship(s) and estimated its velocity. It is important to keep the track of the ship movement and velocity for surveillance of oil tankers and large vessels, ply in the shipping routes for possible assessment of oil spill and defense applications. The ships while moving uses fossil fuel and release their exhaust in the form of Sulfur dioxide (SO2) gas. This Sulfur dioxide when comes in contact with water vapour, leads to the formation of Sulfate Aerosol's. These aerosol's act as the nuclei or 'seeds', these nuclei are called as cloud condensation nuclei (CCN), around which cloud droplets take shape and together these droplets form clouds. Narrow lines of perturbed regions in marine stratiform clouds, caused by moving ships, appear brighter in satellite imagery. They can also appear as narrow lines of clouds in an otherwise cloud-free sky. Ship tracks are the long lived cloud lines that are formed from ship exhaust. The track of large ships is sometimes visualized as a trail, known as ship track. These are typically very long even 500km sometimes, i.e. long enough to be seen in Satellite imagery. These tracks formed in marine boundary layers that were between 300 to 750m height, high relative humidity, small Air-Sea temperature difference (0.5°C), moderate winds (average of 7 m/s) (Durkee et.al 2000).These tracks directly scattering solar radiation back to space and increasing cloud reflectivity through increased droplet concentrations, these clouds reflect much more solar energy than the ocean surface. In Infra red (IR) region the reflectance of the cloud is more compared with visual Bands, and thus we get ship track information
Combining flow routing modelling and direct velocity measurement for optimal discharge estimation
NASA Astrophysics Data System (ADS)
Corato, G.; Moramarco, T.; Tucciarelli, T.
2011-03-01
A new procedure is proposed for estimating river discharge hydrographs during flood events, using only water level data measured at a gauged site, as well as 1-D shallow water modelling and sporadic maximum surface flow velocity measurements. During flood, the piezometric level is surmised constant in the vertical plane of the river section, where the top of the banks is always above the river level, and is well represented by the recorded stage hydrograph. The river is modelled along the reach directly located downstream the upstream gauged section, where discharge hydrograph is sought after. For the stability with respect to the topographic error, as well as for the simplicity of the data required to satisfy the boundary conditions, a diffusive hydraulic model is adopted for flow routing. Assigned boundary conditions are: (1) the recorded stage hydrograph at the upstream river site and (2) the zero diffusion condition at the downstream end of the reach. The MAST algorithm is used for the numerical solution of the flow routing problem, which is embedded in the Brent algorithm used for the computation of the optimum Manning coefficient. Based on synthetic tests concerning a broad prismatic channel, the optimal reach length is chosen so that the approximated downstream boundary condition effects on discharge hydrograph assessment at upstream end are negligible. The roughness Manning coefficient is calibrated by using sporadic instantaneous surface velocity measurements during the rising limb of flood that are turned into instantaneous discharges through the solid of velocity estimated by a two-dimensional entropic model. Several historical events, occurring in three gauged sites along the upper Tiber River wherein a reliable rating curve is available, have been used for the validation. The analysis outcomes can be so summarized: (1) criteria adopted for selecting the optimal channel length and based on synthetic tests have been proved reliable by using field data of
Jensen, Jonas; Olesen, Jacob Bjerring; Stuart, Matthias Bo; Hansen, Peter Møller; Nielsen, Michael Bachmann; Jensen, Jørgen Arendt
2016-08-01
A method for vector velocity volume flow estimation is presented, along with an investigation of its sources of error and correction of actual volume flow measurements. Volume flow errors are quantified theoretically by numerical modeling, through flow phantom measurements, and studied in vivo. This paper investigates errors from estimating volumetric flow using a commercial ultrasound scanner and the common assumptions made in the literature. The theoretical model shows, e.g. that volume flow is underestimated by 15%, when the scan plane is off-axis with the vessel center by 28% of the vessel radius. The error sources were also studied in vivo under realistic clinical conditions, and the theoretical results were applied for correcting the volume flow errors. Twenty dialysis patients with arteriovenous fistulas were scanned to obtain vector flow maps of fistulas. When fitting an ellipsis to cross-sectional scans of the fistulas, the major axis was on average 10.2mm, which is 8.6% larger than the minor axis. The ultrasound beam was on average 1.5mm from the vessel center, corresponding to 28% of the semi-major axis in an average fistula. Estimating volume flow with an elliptical, rather than circular, vessel area and correcting the ultrasound beam for being off-axis, gave a significant (p=0.008) reduction in error from 31.2% to 24.3%. The error is relative to the Ultrasound Dilution Technique, which is considered the gold standard for volume flow estimation for dialysis patients. The study shows the importance of correcting for volume flow errors, which are often made in clinical practice.
NASA Technical Reports Server (NTRS)
Roussel-Dupre, R.
1979-01-01
It was shown that, in the presence of the steep temperature gradients characteristic of EUV models of the solar transition region, the electron and proton velocity distribution functions are non-Maxwellian and are characterized by high energy tails. The magnitude of these tails are estimated for a model of the transition region and the heat flux is calculated at a maximum of 30 percent greater than predicted by collision-dominated theory.
Kadowaki, Hiroko; Hayase, Toshiyuki; Funamoto, Kenichi; Taniguchi, Nobuyuki
2016-02-01
Information on hemodynamics is essential for elucidation of mechanisms and development of novel diagnostic methods for circulatory diseases. Two-dimensional ultrasonic-measurement-integrated (2D-UMI) simulation can correctly reproduce an intravascular blood flow field and hemodynamics by feeding back an ultrasonic measurement to the numerical blood flow simulation. In this method, it is critically important to give the correct cross-sectional average inflow velocity (inflow velocity) as the boundary condition. However, systematic study has not been done on the relative validity and effectiveness of existing inflow velocity estimation methods for various target flow fields. The aim of this study was to examine the existing methods systematically and to establish a method to accurately estimate inflow velocities for various vessel geometries and flow conditions in 2D-UMI simulations. A numerical experiment was performed for 2D-UMI simulation of blood flow models in a straight vessel with inflow velocity profiles symmetric and asymmetric to the vessel axis using existing evaluation functions based on Doppler velocity error for the inflow velocity estimation. As a result, it was clarified that a significantly large estimation error occurs in the asymmetric flow due to a nonfeedback domain near the downstream end of the calculation domain. Hence, a new inflow velocity estimation method of 2D-UMI simulation is proposed in which the feedback and evaluation domains are extended to the downstream end. Further numerical experiments of 2D-UMI simulation for two realistic vessel geometries of a healthy blood vessel and a stenosed one confirmed the effectiveness of the proposed method.
Kadowaki, Hiroko; Hayase, Toshiyuki; Funamoto, Kenichi; Taniguchi, Nobuyuki
2016-02-01
Information on hemodynamics is essential for elucidation of mechanisms and development of novel diagnostic methods for circulatory diseases. Two-dimensional ultrasonic-measurement-integrated (2D-UMI) simulation can correctly reproduce an intravascular blood flow field and hemodynamics by feeding back an ultrasonic measurement to the numerical blood flow simulation. In this method, it is critically important to give the correct cross-sectional average inflow velocity (inflow velocity) as the boundary condition. However, systematic study has not been done on the relative validity and effectiveness of existing inflow velocity estimation methods for various target flow fields. The aim of this study was to examine the existing methods systematically and to establish a method to accurately estimate inflow velocities for various vessel geometries and flow conditions in 2D-UMI simulations. A numerical experiment was performed for 2D-UMI simulation of blood flow models in a straight vessel with inflow velocity profiles symmetric and asymmetric to the vessel axis using existing evaluation functions based on Doppler velocity error for the inflow velocity estimation. As a result, it was clarified that a significantly large estimation error occurs in the asymmetric flow due to a nonfeedback domain near the downstream end of the calculation domain. Hence, a new inflow velocity estimation method of 2D-UMI simulation is proposed in which the feedback and evaluation domains are extended to the downstream end. Further numerical experiments of 2D-UMI simulation for two realistic vessel geometries of a healthy blood vessel and a stenosed one confirmed the effectiveness of the proposed method. PMID:26241967
Estimating head-related transfer functions of human subjects from pressure-velocity measurements.
Hiipakka, Marko; Kinnari, Teemu; Pulkki, Ville
2012-05-01
Direct measurements of individual head-related transfer functions (HRTFs) with a probe microphone at the eardrum are unpleasant, risky, and unreliable and therefore have not been widely used. Instead, the HRTFs are commonly measured from the blocked ear canal entrance, which excludes the effects of the individual ear canals and eardrums. This paper presents a method that allows obtaining individually correct magnitude frequency responses of HRTFs at the eardrum from pressure-velocity (PU) measurements at the ear canal entrance with a miniature PU sensor. The HRTFs of 25 test subjects with nine directions of sound incidence were estimated using real anechoic measurements and an energy-based estimation method. To validate the approach, measurements were also conducted with probe microphones near the eardrums as well as at blocked ear canal entrances. Comparisons between the different methods show that the method presented is a valid and reliable technique for obtaining magnitude frequency responses of HRTFs. The HRTF filters designed using the PU measurements are also shown to yield more correct frequency responses at the eardrum than the filters designed using measurements from the blocked ear canal entrance.
DO QUASAR BROAD-LINE VELOCITY WIDTHS ADD ANY INFORMATION TO VIRIAL BLACK HOLE MASS ESTIMATES?
Croom, Scott M.
2011-08-01
We examine how much information measured broad-line widths add to virial black hole (BH) mass estimates for flux-limited samples of quasars. We do this by comparing the BH mass estimates to those derived by randomly reassigning the quasar broad-line widths to different objects and re-calculating the BH mass. For 9000 BH masses derived from the H{beta} line we find that the distributions of original and randomized BH masses in the M{sub BH}-redshift plane and the M{sub BH}-luminosity plane are formally identical. A two-dimensional Kolmogorov-Smirnov test does not find a difference at >90% confidence. For the Mg II line (32,000 quasars) we do find very significant differences between the randomized and original BH masses, but the amplitude of the difference is still small. The difference for the C IV line (14,000 quasars) is 2{sigma}-3{sigma} and again the amplitude of the difference is small. Subdividing the data into redshift and luminosity bins we find that the median absolute difference in BH mass between the original and randomized data is 0.025, 0.01, and 0.04 dex for H{beta}, Mg II, and C IV, respectively. The maximum absolute difference is always {<=}0.1 dex. We investigate whether our results are sensitive to corrections to Mg II virial masses, such as those suggested by Onken and Kollmeier. These corrections do not influence our results, other than to reduce the significance of the difference between original and randomized BH masses to only 1{sigma}-2{sigma} for Mg II. Moreover, we demonstrate that the correlation between mass residuals and Eddington ratio discussed by Onken and Kollmeier is more directly attributable to the slope of the relation between H{beta} and Mg II line width. The implication is that the measured quasar broad-line velocity widths provide little extra information, after allowing for the mean velocity width. In this case virial estimates are equivalent to M{sub BH}{proportional_to}L{sup {alpha}}, with L/L{sub Edd
Estimating Discharge using Multi-level Velocity Data from Acoustic Doppler Instruments
NASA Astrophysics Data System (ADS)
Bang Poulsen, J.; Rømer Rasmussen, K.; Bering Ovesen, N.
2010-12-01
In the majority of Danish streams, weed growth affects the effective stream width and bed roughness and therefore imposes temporal variations on the stage-discharge relationship. Small stream-gradients and firm ecology based restrictions prevent that hydraulic structures are made at the discharge stations and thus remove or limit such influences. Hence, estimation of the hydrograph is based on continuous stream gauging combined with monthly control measurements of discharge and assuming linear variation of bed roughness between the monthly measurements. As a result, any non-linear drift in weed density or structure which affect the frictional characteristics of the stream during both normal and peak flows are ignored. The present investigation studies if such temporal variation in the conveyance may be detected and eventually compensated for when estimating the hydrograph. Therefore acoustic Dopplers have been placed at the main discharge station in one of the largest Danish catchments (the Skjern). The instruments were set out in early February 2010 during the winter season and have been running since then. The long term average discharge at the station is near 14 m3/s and the cross sectional profile is roughly trapezoidal having width about 15 m., but slightly skew so that the stream is about 0.5 m. deeper off the right than off the left bank. During winter, the depths are typically near 2 m. while during summer they are about 1.5 m. During peak flows, when the discharge exceeds 35 m3/s, the depth increases to more than 3 m. The Doppler instruments (Nortek) are placed on a vertical pole about 2 m. off the right bank at three fixed elevations above the streambed (0.3, 0.6, and 1.3 m); the beams point horizontally towards the left bank perpendicularly to the average flow direction. At each depth, the Doppler sensor records 10 minute average stream velocities in the central 10 m. section of the stream. During summer periods with low flow, stream velocity has only
NASA Astrophysics Data System (ADS)
Bradford, John H.; Harper, Joel T.
2005-04-01
Normal-moveout velocity analysis can lead to significant overestimates of the velocity structure of temperate glaciers since most englacial reflectors approximate point scatters and violate the assumption of planar flat lying reflectors. Migration velocity analysis (MVA) is a tool that does not depend on the assumption of flat lying reflectors. MVA can provide laterally and vertically continuous velocity estimates from conventional common-offset radar sections. In a study of temperate Bench Glacier, Alaska, we used MVA coupled with dielectric modeling to estimate the distribution of water content along a cross-section of the glacier. We found the glacier has two layers, an upper layer with relatively low water content, and lower layer with relatively high water content. The ability to quantify hydrostratigraphy is important in understanding water storage and routing within glaciers.
NASA Astrophysics Data System (ADS)
Zordan, Jessica; Schleiss, Anton J.; Franca, Mário J.
2016-04-01
Density or gravity currents are geophysical flows driven by density gradients between two contacting fluids. The physical trigger mechanism of these phenomena lays in the density differences which may be caused by differences in the temperature, dissolved substances or concentration of suspended sediments. Saline density currents are capable to entrain bed sediments inducing signatures in the bottom of sedimentary basins. Herein, saline density currents are reproduced in laboratory over a movable bed. The experimental channel is of the lock-exchange type, it is 7.5 m long and 0.3 m wide, divided into two sections of comparable volumes by a sliding gate. An upstream reach serves as a head tank for the dense mixture; the current propagates through a downstream reach where the main measurements are made. Downstream of the channel a tank exist to absorb the reflection of the current and thus artifacts due to the limited length of the channel. High performance thermoplastic polyurethane simulating fine sediments forms the movable bed. Measures of 3D instantaneous velocities will be made with the use of the non-intrusive technique of the ADV (Acoustic Doppler Current Profiler). With the velocity measurements, the evolution in time of the channel-bed shear stress due the passage of gravity currents is estimated. This is in turn related to the observed erosion and to such parameters determinant for the dynamics of the current as initial density difference, lock length and channel slope. This work was funded by the ITN-Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme FP7-PEOPLE-2013-ITN under REA grant agreement n_607394-SEDITRANS.
Aeroacoustics of volcanic jets: Acoustic power estimation and jet velocity dependence
NASA Astrophysics Data System (ADS)
Matoza, Robin S.; Fee, David; Neilsen, Tracianne B.; Gee, Kent L.; Ogden, Darcy E.
2013-12-01
A fundamental goal of volcano acoustics is to relate observed infrasonic signals to the eruptive processes generating them. A link between acoustic power Π
Mesin, Luca; Damiano, Luisa; Farina, Dario
2007-03-15
The aim of this simulation study was to assess the bias in estimating muscle fiber conduction velocity (CV) from surface electromyographic (EMG) signals in muscles with one and two pinnation angles. The volume conductor was a layered medium simulating anisotropic muscle tissue and isotropic homogeneous subcutaneous tissue. The muscle tissue was homogeneous for one pinnation angle and inhomogeneous for bipinnate muscles (two fiber directions). Interference EMG signals were obtained by simulating recruitment thresholds and discharge patterns of a set of 100 and 200 motor units for the pinnate and bipinnate muscle, respectively (15 degrees pinnation angel in both cases). Without subcutaneous layer and muscle fibers with CV 4m/s, average CV estimates from the pinnate (bipinnate) muscle were 4.81+/-0.18 m/s (4.80+/-0.18 m/s) for bipolar, 4.71+/-0.19 m/s (4.71+/-0.12 m/s) for double differential, and 4.78+/-0.16 m/s (4.79+/-0.15m/s) for Laplacian recordings. When subcutaneous layer was added (thickness 1mm) in the same conditions, estimated CV values were 4.93+/-0.25 m/s (5.16+/-0.41 m/s), 4.70+/-0.21 m/s (4.83+/-0.33 m/s), and 4.89+/-0.21 m/s (4.99+/-0.39 m/s), for the three recording systems, respectively. The main factor biasing CV estimates was the propagation of action potentials in the two directions which influenced the recording due to the scatter of the projection of end-plate and tendon locations along the fiber direction, as a consequence of pinnation. The same problem arises in muscles with the line of innervation zone locations not perpendicular to fiber direction. These results indicate an important limitation in reliability of CV estimates from the interference EMG when the innervation zone and tendon locations are not distributed perpendicular to fiber direction.
Rupture Velocity of the 2001 Kunlun, China, Event Estimated From SEM Waveform Modeling
NASA Astrophysics Data System (ADS)
Hjörleifsdóttir, V.; Kanamori, H.; Tromp, J.
2003-12-01
The rupture speed during an earthquake is controlled by the energy dissipated mechanically during faulting. Rupture velocities close to the limiting speed imply that very little energy is going into the fracture and thus has implications for whether the rupture will continue to grow or stop. The Mw~7.9, November~14, 2001, Kunlun, China, strike-slip event ruptured unilaterally over 400 km along the Kunlun fault. The long rupture combined with worldwide broad-band instrumentation provides us with a unique opportunity to estimate the rupture speed. Unfortunately, the strike-slip nature of the faulting causes the body waves recorded at teleseismic distances to be nearly nodal, making body-wave modeling very difficult. We use the spectral-element method (SEM) and a 3D Earth model to accurately compute waveforms at periods of 18 seconds and longer for this event. We compute synthetics for two source models. We use (a) a body-wave model with an average rupture speed of 3.5 km/s, similar to the model reported by Kikuchi and Yamanaka (2001) and (b) a surface-wave model proposed by Bouchon and Vallée (2003) with an average rupture speed of 4.3 km/s and a slip distribution constrained by measured surface offsets. Both models show similar fits to the surface-wave radiation pattern at periods above 100 seconds and thus we turn to long-period body waves to discriminate between the two. The event comprised several smaller subevents, with the largest subevent occurring about 60 seconds after the initiation of rupture. The azimuthal variation in arrival time of this phase depends on the rupture velocity. Using the Bouchon and Vallée model we find that shear waves from the large subevent arrive about 10 seconds earlier than observed in the direction of rupture, whereas they arrive on time in the anti-rupture direction. A similar phase shift is observed in the short period surface waves. As this azimuthal variation is not evident for the Kikuchi and Yamanaka model, we conclude that
NASA Astrophysics Data System (ADS)
Kamei, R.; Lumley, D. E.
2015-12-01
Passive seismic monitoring of natural or induced seismicity can provide important information about time-variant subsurface phenomena, especially concerning fluid flow and stress-strain conditions. Traditional monitoring focuses on locating seismic events, and interpreting the results in terms of changes to subsurface properties. Instead, we directly estimate the subsurface velocity changes, which can be more quantitatively related to changes in fluid and stress states via rock physics and geomechanical relationships. The expected velocity changes are often so small that conventional traveltime tomography has difficulty in providing reliable detailed estimates. Our method is based on full waveform inversion (FWI) of the seismic data. FWI estimates a high-resolution subsurface model by fitting waveforms in the data domain based on a numerical solution to the wave equation. We evaluate the performance of our FWI by using a synthetic set of a limited number (up to three) repeating events recorded at a surface array of sensors. We use a realistic complex velocity model which includes fine-scale heterogeneity, and consider the case where fluid pore pressure has changed the stress state leading to a small velocity increase in two distinct thin layers. We assume that we have reasonable estimates of the event locations and the background velocity model before starting the inversion. We compare parallel, double-difference and bootstrapping techniques, and analyse effects of accuracy in the background velocity model to the inversion. FWI retrieves the correct velocity change with excellent accuracy at a high spatial resolution less than one wavelength. This is due to the ability of FWI to invert the full waveform data, rather than traveltime arrivals only. We analyse the inversion sensitivity kernels and show that the spatial resolution improves, and the required density of the sensor array reduces, for velocity changes nearer to the seismic source location.
Xiao, Kun; Zou, Changchun; Xiang, Biao; Liu, Jieqiong
2013-01-01
Gas hydrate model and free gas model are established, and two-phase theory (TPT) for numerical simulation of elastic wave velocity is adopted to investigate the unconsolidated deep-water sedimentary strata in Shenhu area, South China Sea. The relationships between compression wave (P wave) velocity and gas hydrate saturation, free gas saturation, and sediment porosity at site SH2 are studied, respectively, and gas hydrate saturation of research area is estimated by gas hydrate model. In depth of 50 to 245 m below seafloor (mbsf), as sediment porosity decreases, P wave velocity increases gradually; as gas hydrate saturation increases, P wave velocity increases gradually; as free gas saturation increases, P wave velocity decreases. This rule is almost consistent with the previous research result. In depth of 195 to 220 mbsf, the actual measurement of P wave velocity increases significantly relative to the P wave velocity of saturated water modeling, and this layer is determined to be rich in gas hydrate. The average value of gas hydrate saturation estimated from the TPT model is 23.2%, and the maximum saturation is 31.5%, which is basically in accordance with simplified three-phase equation (STPE), effective medium theory (EMT), resistivity log (Rt), and chloride anomaly method.
Mazumder, Mohit; Padhan, Narendra; Bhattacharya, Alok; Gourinath, Samudrala
2014-01-01
The diversity of functions carried out by EF hand-containing calcium-binding proteins is due to various interactions made by these proteins as well as the range of affinity levels for Ca²⁺ displayed by them. However, accurate methods are not available for prediction of binding affinities. Here, amino acid patterns of canonical EF hand sequences obtained from available crystal structures were used to develop a classifier that distinguishes Ca²⁺-binding loops and non Ca²⁺-binding regions with 100% accuracy. To investigate further, we performed a proteome-wide prediction for E. histolytica, and classified known EF-hand proteins. We compared our results with published methods on the E. histolytica proteome scan, and demonstrated our method to be more specific and accurate for predicting potential canonical Ca²⁺-binding loops. Furthermore, we annotated canonical EF-hand motifs and classified them based on their Ca²⁺-binding affinities using support vector machines. Using a novel method generated from position-specific scoring metrics and then tested against three different experimentally derived EF-hand-motif datasets, predictions of Ca²⁺-binding affinities were between 87 and 90% accurate. Our results show that the tool described here is capable of predicting Ca²⁺-binding affinity constants of EF-hand proteins.
Leff, P; Harper, D; Dainty, I A; Dougall, I G
1990-09-01
1. Recent theoretical studies have questioned the pharmacological estimation of agonist affinity. They showed that when receptor isomerisation or ternary complex mechanisms operate, the receptor inactivation method can substantially overestimate affinity, whereas methods for partial agonist analysis are more accurate. We previously suggested that the operation of such mechanisms and therefore the presence of errors could be detected by analysing the same partial agonist by the receptor inactivation and comparative methods. This paper describes the practical application of this test. 2. The ternary complex mechanism was simulated for a partial agonist under various conditions relating receptor (R) and transducer (T) concentrations, one of which also corresponds to the receptor isomerisation mechanism. The theoretical data so generated were then analysed by the inactivation and comparative methods to quantify the magnitude of error of affinity estimation that could occur. 3. This analysis showed that for a partial agonist with approximately 85% of the activity of a full agonist, the inactivation method could produce an affinity (pKA) estimate up to 0.7 log10 units higher than that produced by the comparative method. This difference would occur when the total receptor concentration ([R0]) is less than or equal to the total transducer concentration ([T0]). It also showed that the overestimation of affinity by the inactivation method was accompanied by drastic overestimation of Em, the maximal effect parameter. 4. The test was then exemplified using the muscarinic receptor system in the guinea-pig isolated left atrial preparation, where there is evidence that a ternary complex mechanism operates. The test agonist was pilocarpine, which produced on average 83% of the activity of the full agonist, carbachol. Pilocarpine was analysed in comparison with carbachol and by receptor inactivation in the same tissue resulting in small and statistically insignificant differences
NASA Astrophysics Data System (ADS)
Balachandar, Settu; Shivaprakash, N. C.; Kameswara Rao, L.
2016-01-01
A new approach is proposed to estimate the thermal diffusivity of optically transparent solids at ambient temperature based on the velocity of an effective temperature point (ETP), and by using a two-beam interferometer the proposed concept is corroborated. 1D unsteady heat flow via step-temperature excitation is interpreted as a ‘micro-scale rectilinear translatory motion’ of an ETP. The velocity dependent function is extracted by revisiting the Fourier heat diffusion equation. The relationship between the velocity of the ETP with thermal diffusivity is modeled using a standard solution. Under optimized thermal excitation, the product of the ‘velocity of the ETP’ and the distance is a new constitutive equation for the thermal diffusivity of the solid. The experimental approach involves the establishment of a 1D unsteady heat flow inside the sample through step-temperature excitation. In the moving isothermal surfaces, the ETP is identified using a two-beam interferometer. The arrival-time of the ETP to reach a fixed distance away from heat source is measured, and its velocity is calculated. The velocity of the ETP and a given distance is sufficient to estimate the thermal diffusivity of a solid. The proposed method is experimentally verified for BK7 glass samples and the measured results are found to match closely with the reported value.
NASA Astrophysics Data System (ADS)
Irving, James D.
-receiver angles, this energy likely travels between the antenna tips. Using this knowledge, I develop an improved inversion methodology for crosshole GPR data. In addition to inverting for subsurface velocities, I estimate a small number of parameters that describe a travel-time correction curve as a function of ray angle. I then show the successful application of this improved inversion methodology to synthetic crosshole GPR data, and a data set collected at the Boise Hydrogeophysical Research Site.
NASA Technical Reports Server (NTRS)
Roth, D. J.; Swickard, S. M.; Stang, D. B.; Deguire, M. R.
1990-01-01
A review and statistical analysis of the ultrasonic velocity method for estimating the porosity fraction in polycrystalline materials is presented. Initially, a semi-empirical model is developed showing the origin of the linear relationship between ultrasonic velocity and porosity fraction. Then, from a compilation of data produced by many researchers, scatter plots of velocity versus percent porosity data are shown for Al2O3, MgO, porcelain-based ceramics, PZT, SiC, Si3N4, steel, tungsten, UO2,(U0.30Pu0.70)C, and YBa2Cu3O(7-x). Linear regression analysis produced predicted slope, intercept, correlation coefficient, level of significance, and confidence interval statistics for the data. Velocity values predicted from regression analysis for fully-dense materials are in good agreement with those calculated from elastic properties.
NASA Technical Reports Server (NTRS)
Roth, D. J.; Swickard, S. M.; Stang, D. B.; Deguire, M. R.
1991-01-01
A review and statistical analysis of the ultrasonic velocity method for estimating the porosity fraction in polycrystalline materials is presented. Initially, a semiempirical model is developed showing the origin of the linear relationship between ultrasonic velocity and porosity fraction. Then, from a compilation of data produced by many researchers, scatter plots of velocity versus percent porosity data are shown for Al2O3, MgO, porcelain-based ceramics, PZT, SiC, Si3N4, steel, tungsten, UO2,(U0.30Pu0.70)C, and YBa2Cu3O(7-x). Linear regression analysis produces predicted slope, intercept, correlation coefficient, level of significance, and confidence interval statistics for the data. Velocity values predicted from regression analysis of fully-dense materials are in good agreement with those calculated from elastic properties.
NASA Astrophysics Data System (ADS)
Ivan, Marian; Ghica, Daniela Veronica; Gosar, Andrej; Hatzidimitriou, Panagiotis; Hofstetter, Rami; Polat, Gulten; Wang, Rongjiang
2015-02-01
Lowermost mantle velocity in the area 15°S-70°N latitude/60°W-5° W longitude is estimated using two groups of observations, complementary to each other. There are 894 Pdif observations at stations in the Balkan and Eastern Mediterranean areas from 15 major earthquakes in Central and South America. Another 218 Pdif observations are associated with four earthquakes in Greece/Turkey and one event in Africa, recorded by American stations. A Pdif slowness tomographic approach of the structures immediately above the core-to-mantle boundary (CMB) is used, incorporating corrections for ellipticity, station elevation and velocity perturbations along the ray path. A low-velocity zone above CMB with a large geographical extent, approximately in the area (35-65°N) × (40-20°W), appears to have the velocity perturbations exceeding the value actually assumed by some global models. Most likely, it is extended beneath western Africa. A high-velocity area is observed west of the low-velocity zone. The results suggest that both Cape Verde and Azorean islands are located near transition areas from low-to-high velocity values in the lowermost mantle.
NASA Astrophysics Data System (ADS)
de Poyferré, Thibault; Nguyen, Quang-Huy
2016-07-01
We consider the gravity-capillary waves in any dimension and in fluid domains with general bottoms. Using the paradifferential reduction established in [19], we prove Strichartz estimates for solutions to this problem, at a low regularity level such that initially, the velocity field can be non-Lipschitz up to the free surface. We then use those estimates to solve the Cauchy problem at this level of regularity.
Calibrated Tully-Fisher relations for improved estimates of disc rotation velocities
NASA Astrophysics Data System (ADS)
Reyes, R.; Mandelbaum, R.; Gunn, J. E.; Pizagno, J.; Lackner, C. N.
2011-11-01
In this paper, we derive scaling relations between photometric observable quantities and disc galaxy rotation velocity Vrot or Tully-Fisher relations (TFRs). Our methodology is dictated by our purpose of obtaining purely photometric, minimal-scatter estimators of Vrot applicable to large galaxy samples from imaging surveys. To achieve this goal, we have constructed a sample of 189 disc galaxies at redshifts z < 0.1 with long-slit Hα spectroscopy from Pizagno et al. and new observations. By construction, this sample is a fair subsample of a large, well-defined parent disc sample of ˜170 000 galaxies selected from the Sloan Digital Sky Survey Data Release 7 (SDSS DR7). The optimal photometric estimator of Vrot we find is stellar mass M★ from Bell et al., based on the linear combination of a luminosity and a colour. Assuming a Kroupa initial mass function (IMF), we find: log [V80/(km s-1)] = (2.142 ± 0.004) + (0.278 ± 0.010)[log (M★/M⊙) - 10.10], where V80 is the rotation velocity measured at the radius R80 containing 80 per cent of the i-band galaxy light. This relation has an intrinsic Gaussian scatter ? dex and a measured scatter σmeas= 0.056 dex in log V80. For a fixed IMF, we find that the dynamical-to-stellar mass ratios within R80, (Mdyn/M★)(R80), decrease from approximately 10 to 3, as stellar mass increases from M★≈ 109 to 1011 M⊙. At a fixed stellar mass, (Mdyn/M★)(R80) increases with disc size, so that it correlates more tightly with stellar surface density than with stellar mass or disc size alone. We interpret the observed variation in (Mdyn/M★)(R80) with disc size as a reflection of the fact that disc size dictates the radius at which Mdyn/M★ is measured, and consequently, the fraction of the dark matter 'seen' by the gas at that radius. For the lowest M★ galaxies, we find a positive correlation between TFR residuals and disc sizes, indicating that the total density profile is dominated by dark matter on these scales. For the
Delles, Michael; Rengier, Fabian; Ley, Sebastian; von Tengg-Kobligk, Hendrik; Kauczor, Hans-Ulrich; Dillmann, Rüdiger; Unterhinninghofen, Roland
2011-01-01
In cardiovascular diagnostics, phase-contrast MRI is a valuable technique for measuring blood flow velocities and computing blood pressure values. Unfortunately, both velocity and pressure data typically suffer from the strong image noise of velocity-encoded MRI. In the past, separate approaches of regularization with physical a-priori knowledge and data representation with continuous functions have been proposed to overcome these drawbacks. In this article, we investigate polynomial regularization as an exemplary specification of combining these two techniques. We perform time-resolved three-dimensional velocity measurements and pressure gradient computations on MRI acquisitions of steady flow in a physical phantom. Results based on the higher quality temporal mean data are used as a reference. Thereby, we investigate the performance of our approach of polynomial regularization, which reduces the root mean squared errors to the reference data by 45% for velocities and 60% for pressure gradients.
NASA Astrophysics Data System (ADS)
Takagishi, M.; Kinoshita, S.
2011-12-01
We estimated the velocity boundaries in a sedimentary layer-basement system in Yokohama by applying nonstationary ray decomposition method (NRDM) to the strong motion data recorded at the Yokohama dense strong motion array (YKH array). NRDM is a method to estimate the velocity boundaries of real layered structure from surface recordings by decomposing power of an SH-wave into instantaneous power of wave associated with rays in a homogeneous half space. The estimated results obtained by applying this method to seismograms are represented as a function of lapse time and depth time, which is travel time from surface toward depth-direction. A total of 10080 surface seismograms obtained at the YKH array for the 128 earthquakes that occurred in the Kanto area from 2000 to 2010 were used. The recordings were measured by acceleration seismometers. The data were obtained for the events having JMA magnitudes in the range of from 2.8 to 6.5. NRDM was applied to the transverse component data of velocity seismogram. Since the seismograms obtained at the YKH array predominate in high frequencies due to the weak subsurface structure, we applied bandpass filtering to the seismograms by using several intrinsic mode functions that are narrowband signals with different center frequencies. After such a processing, the data were converted to analytic signals, and then, the signals were used to estimate the instantaneous power by means of Wigner-Ville distribution. We have estimated the velocity boundaries in sediment in Yokohama region using 37 sites which were located in a rectangular area with a width of 4 km and a length of 40 km south-southeast of the FCH array. We were able to estimate two velocity boundaries, one in sediment (K-M) and the other being the upper boundary of the pre-Tertiary basement (M-B). On the whole, the upper boundary of the pre-Tertiary basement is dipping toward the south-southeast. The estimated depth times at K-M and M-B were from 1.5 to 2.2 s and from 2
NASA Technical Reports Server (NTRS)
Mach, Douglas M.; Rust, W. D.
1993-01-01
Velocities, optical risetimes, and transmission line model peak currents for seven natural positive return strokes are reported. The average 2D positive return stroke velocity for channel segments of less than 500 m in length starting near the base of the channel is 0.8 +/- 0.3 x 10 exp 8 m/s, which is slower than the present corresponding average velocity for natural negative first return strokes of 1.7 +/- 0.7 x 10 exp 8/s. It is inferred that positive stroke peak currents in the literature, which assume the same velocity as negative strokes, are low by a factor of 2. The average 2D positive return stroke velocity for channel segments of greater than 500 m starting near the base of the channel is 0.9 +/- 0.4 x 10 exp 8 m/s. The corresponding average velocity for the present natural negative first strokes is 1.2 +/- 0.6 x 10 exp 8 m/s. No significant velocity change with height is found for positive return strokes.
Shallow Subsurface Velocity Estimation Using Traffic Noise at Long Beach, CA
NASA Astrophysics Data System (ADS)
Chang, J. P.; de Ridder, S.; Biondi, B. C.
2015-12-01
We demonstrate the effectiveness of using traffic noise for shallow subsurface imaging using a dense seismic array in Long Beach, California. Spectral analysis indicates that traffic-induced vibrations dominate the ambient seismic noise field at frequencies between 3 and 15 Hz. Using the ambient-noise cross-correlation technique, we extract fundamental and first-order Rayleigh waves generated by Interstate 405 and local roads. After accounting for the local noise source distribution, we pick group travel times associated with the fundamental mode and use them in a straight-ray tomography procedure to generate group velocity maps at 3.0 Hz and 3.5 Hz. The velocity trends in our results correspond to shallow depths and are consistent with lithologies outlined in a geologic map of the survey area. The most prominent features resolved in our velocity maps are the low velocities to the north corresponding to less-consolidated materials, high velocities to the south corresponding to more-consolidated materials, a low-velocity zone corresponding to artificial fill in Alamitos Bay, and a low-velocity linear feature in the Newport-Inglewood Fault zone. Our results have important applications for research investigations concerned with the shallow subsurface, such as geohazard mapping.
NASA Astrophysics Data System (ADS)
Sarry, L.; Peng, Y. J.; Boire, J. Y.
2002-01-01
In previously published studies, blood flow velocity from x-ray biplane angiography was measured by solving an inverse advection problem, relating velocity to bolus densities summed across sections. Both spatial and temporal velocity variations were recovered through a computationally expensive parameter estimation algorithm. Here we prove the existence and uniqueness of the solution on three sub-domains of the plane defined by the axial position along the vessel and the time of the angiographic sequence. A fast direct scheme was designed in conjunction with a regularization step stemming from the volume flow conservation law applied on consecutive segments. Its accuracy and immunity towards noise were tested on both simulated and real densitometric data. The relative error between the estimated and expected velocities was less than 5% for more than 90% of the points of the spatiotemporal plane with simulated densities normalized to 1.0 and a Gaussian additive noise of standard deviation 0.01. For densities reconstructed from a biplane angiographic sequence, increase in velocity is used as a functional index for the stenosis ratio and to characterize the sharing of flow at bifurcation.
Bertsatos, Ioannis; Makris, Nicholas C
2011-07-01
Doppler analysis has been extensively used in active radar and sonar sensing to estimate the speed and direction of a single target within an imaging system resolution cell following deterministic theory. For target swarms, such as fish and plankton in the ocean, and raindrops, birds and bats in the atmosphere, multiple randomly moving targets typically occupy a single resolution cell, making single-target theory inadequate. Here, a method is developed for simultaneously estimating the instantaneous mean velocity and position of a group of randomly moving targets within a resolution cell, as well as the respective standard deviations across the group by Doppler analysis in free-space and in a stratified ocean waveguide. While the variance of the field scattered from the swarm is shown to typically dominate over the mean in the range-velocity ambiguity function, cross-spectral coherence remains and maintains high Doppler velocity and position resolution even for coherent signal processing algorithms such as the matched filter. For pseudo-random signals, the mean and variance of the swarms' velocity and position can be expressed in terms of the first two moments of the measured range-velocity ambiguity function. This is shown analytically for free-space and with Monte-Carlo simulations for an ocean waveguide.
NASA Astrophysics Data System (ADS)
Ma, Zeyu; Zhang, Yunqing; Yang, James
2016-02-01
A precise estimation of vehicle velocities can be valuable for improving the performance of the vehicle dynamics control (VDC) system and this estimation relies heavily upon the accuracy of longitudinal and lateral tyre force calculation governed by the prediction of normal tyre forces. This paper presents a computational method based on the unscented Kalman filter (UKF) method to estimate both longitudinal and lateral velocities and develops a novel quasi-stationary method to predict normal tyre forces of heavy trucks on a sloping road. The vehicle dynamic model is constructed with a planar dynamic model combined with the Pacejka tyre model. The novel quasi-stationary method for predicting normal tyre forces is able to characterise the typical chassis configuration of the heavy trucks. The validation is conducted through comparing the predicted results with those simulated by the TruckSim and it has a good agreement between these results without compromising the convergence speed and stability.
ERIC Educational Resources Information Center
Gray, Gary R.
1980-01-01
Presents selected recent advances in immobilization chemistry which have important connections to affinity chromatography. Discusses ligand immobilization and support modification. Cites 51 references. (CS)
NASA Astrophysics Data System (ADS)
Yamaguchi, Makoto; Midorikawa, Saburoh
The empirical equation for estimating the site amplification factor of ground motion by the average shear-wave velocity of ground (AVS) is examined. In the existing equations, the coefficient on dependence of the amplification factor on the AVS was treated as constant. The analysis showed that the coefficient varies with change of the AVS for short periods. A new estimation equation was proposed considering the dependence on the AVS. The new equation can represent soil characteristics that the softer soil has the longer predominant period, and can make better estimations for short periods than the existing method.
NASA Astrophysics Data System (ADS)
Kuznetsov, G. N.; Kuz'kin, V. M.; Pereselkov, S. A.; Prosovetskiy, D. Yu.
2016-09-01
We describe an algorithm for estimating the radial component of the velocity of a sound source based on information about frequency shifts of the interference maxima of the field and consider the problem of its interference immunity. We obtain the limit estimate for the value of the input signal/noise ratio when the algorithm is working effectively. We present results of computational and field experiments using a single receiver and a horizontal array. We compare the experimental data with analytic interference immunity estimates.
NASA Astrophysics Data System (ADS)
Sedek, Mohamed; Gross, Lutz; Tyson, Stephen
2016-07-01
We present a new computational method of automatic normal moveout (NMO) correction that not only accurately flattens and corrects the far offset data, but simultaneously provides NMO velocity (v_nmo ) for each individual seismic trace. The method is based on a predefined number of NMO velocity sweeps using linear vertical interpolation of different NMO velocities at each seismic trace. At each sweep, we measure the semblance between the zero offset trace (pilot trace) and the next seismic trace using a trace-by-trace rather than sample-by-sample based semblance measure; then after all the sweeps are done, the one with the maximum semblance value is chosen, which is assumed to be the most suitable NMO velocity trace that accurately flattens seismic reflection events. Other traces follow the same process, and a final velocity field is then extracted. Isotropic, anisotropic and lateral heterogenous synthetic geological models were built to test the method. A range of synthetic background noise, ranging from 10 to 30 %, was applied to the models. In addition, the method was tested on Hess's VTI (vertical transverse isotropy) model. Furthermore, we tested our method on a real pre-stack seismic CDP gathered from a gas field in Alaska. The results from the presented examples show an excellent NMO correction and extracted a reasonably accurate NMO velocity field.
Torque/velocity properties of human knee muscles: peak and angle-specific estimates.
Caldwell, G E; Adams, W B; Whetstone, M R
1993-09-01
Angle-specific (AS) torque/velocity data have been used to avoid angle related variation in peak torque capacity. However, series elastic structures cause the contractile velocity of active force-producing tissue to differ from external joint velocity except at peak torque. Alternatively, angle related variation may be removed by normalizing peak torque to the isometric maximum at that angular position. The AS, peak (P), and normalized peak (NP) methods were compared in isovelocity knee flexion and extension at velocities between 50 and 250 degrees s-1 for 8 male subjects. The P and NP methods gave more similar torque/velocity relations than the AS method. Further, very little variation in peak torque was attributed to differences in joint angle. Both the P and AS methods illustrate that relative quadriceps/hamstrings torque capability (flexor/extensor ratio) increases slightly with velocity. It is proposed that antagonist muscle torque capabilities should be compared at different angular positions to assess muscular imbalance.
Photoelectric return-stroke velocity and peak current estimates in natural and triggered lightning
NASA Technical Reports Server (NTRS)
Mach, Douglas M.; Rust, W. David
1989-01-01
Two-dimensional photoelectric return stroke velocities from 130 strokes are presented, including 86 negative natural, 41 negative triggered, one positive triggered, and two positive natural return strokes. For strokes starting near the ground and exceeding 500 m in length, the average velocity is 1.3 + or - 0.3 X 10 to the 8th m/s for natural return strokes and 1.2 + or - 0.3 X 10 to the 8th m/s for triggered return strokes. For strokes with lengths less than 500 m, the average velocities are slightly higher. Using the transmission line model (TLM), the shortest segment one-dimensional return stroke velocity, and either the maximum or plateau electric field, it is shown that natural strokes have a peak current distribution that is lognormal with a median value of 16 kA (maximum E) or 12 kA (plateau E). Triggered lightning has a medium peak current value of 21 kA (maximum E) or 15 kA (plateau E). Correlations are found between TLM peak currents and velocities for triggered and natural subsequent return strokes, but not between TLM peak currents and natural first return stroke velocities.
NASA Astrophysics Data System (ADS)
Ristic, Aleksandar Vaso; Petrovacki, Dusan; Govedarica, Miro
2009-08-01
We present a new method to simultaneously estimate cylindrical object radius ( R) and electromagnetic (EM) wave propagation velocity ( v) from ground penetrating radar (GPR) data. R estimation methods have been investigated since the middle of the previous decade, but studies have become more intensive and important over the last several years since they increase the utility of GPR data and enable new GPR applications. Since existing methods, according to the author's best knowledge, are based on a priori known v, the proposed method has an advantage: it eliminates the measurement of v and its influence on R estimation quality. Estimating v accurately results in better soil characterisation. Three steps are used to simultaneously estimate v and R. First, using the extracted raw data, the coordinates of the hyperbola apex ( x0, t0) are estimated. Second, the boundary speed ( v0) is estimated, based on the previous results. In the final step, v is reduced from v0 to a predefined vmin. From the analysis of propagation velocity choice criterion, an optimal v is chosen, which is used to calculate a unique R. This proposed method is a nonlinear least squares fitting procedure. The method is implemented and verified, using data collected under real conditions, in a Matlab environment. A comparison of the proposed and existing methods shows that the new method is significantly more accurate and robust with regard to noise and the amount of raw data.
Meyer, Markus R; Orschiedt, Tina; Maurer, Hans H
2013-02-27
The pharmacokinetics of various important drugs are known to be significantly influenced by the human ABC transporter P-glycoprotein (P-gp), which may lead to clinically relevant drug-drug interactions. In contrast to therapeutic drugs, emerging drugs of abuse (DOA) are sold and consumed without any safety pharmacology testing. Only some studies on their metabolism were published, but none about their affinity to the transporter systems. Therefore, 47 DOAs from various classes were tested for their P-gp affinity using human P-gp (hP-gp) to predict possible drug-drug interactions. DOAs were initially screened for general hP-gp affinity and further characterized by modeling classic Michaelis-Menten kinetics and assessing their K(m) and V(max) values. Among the tested drugs, 12 showed a stimulation of ATPase activity. The most intensive stimulating DOAs were further investigated and compared with the known P-gp model substrates sertraline and verapamil. ATPase stimulation kinetics could be modeled for the entactogen 3,4-methylenedioxy-α-ethylphenethylamine (3,4-BDB), the hallucinogen 2,5-dimethoxy-4-iodoamphetamine (DOI), the abused alkaloid glaucine, the opioid-like drugs N-iso-propyl-1,2-diphenylethylamine (NPDPA), and N-(1-phenylcyclohexyl)-3-ethoxypropanamine (PCEPA), with K(m) and V(max) values within the same range as for verapamil or sertraline. As a consequence interactions with other drugs being P-gp substrates might be considered to be very likely and further studies should be encouraged. PMID:23273999
NASA Astrophysics Data System (ADS)
Shiina, T.; Nakajima, J.; Toyokuni, G.; Kita, S.; Matsuzawa, T.
2014-12-01
A subducting crust contains a large amount of water as a form of hydrous minerals (e.g., Hacker et al., 2003), and the crust plays important roles for water transportation and seismogenesis in subduction zones at intermediate depths (e.g., Kirby et al., 1996; Iwamori, 2007). Therefore, the investigation of seismic structure in the crust is important to understand ongoing physical processes with subduction of oceanic lithosphere. A guided wave which propagates in the subducting crust is recorded in seismograms at Hokkaido, northern Japan (Shiina et al., 2014). Here, we estimated P- and S-wave velocity in the crust with guided waves, and obtained P-wave velocity of 6.6-7.3 km/s and S-wave velocity of 3.6-4.2 km/s at depths of 50-90 km. Moreover, Vp/Vs ratio in the crust is calculated to be 1.80-1.85 in that depth range. The obtained P-wave velocity about 6.6km/s at depths of 50-70 km is consistent with those estimated in Tohoku, northeast Japan (Shiina et al., 2013), and this the P-wave velocity is lower than those expected from models of subducting crustal compositions, such as metamorphosed MORB model (Hacker et al., 2003). In contrast, at greater depths (>80 km), the P-wave velocity marks higher velocity than the case of NE Japan and the velocity is roughly comparable to those of the MORB model. The obtained S-wave velocity distribution also shows characteristics similar to P waves. This regional variation may be caused by a small variation in thermal regime of the Pacific slab beneath the two regions as a result of the normal subduction in Tohoku and oblique subduction in Hokkaido. In addition, the effect of seismic anisotropy in the subducting crust would not be ruled out because rays used in the analysis in Hokkaido propagate mostly in the trench-parallel direction, while those in Tohoku are sufficiently criss-crossed.
Bosquet, Laurent; Duchene, Antoine; Lecot, François; Dupont, Grégory; Leger, Luc
2006-05-01
The purpose of this study was to evaluate the validity of maximal velocity (Vmax) estimated from three-parameter systems models, and to compare the predictive value of two- and three-parameter models for the 800 m. Seventeen trained male subjects (VO2max=66.54+/-7.29 ml min(-1) kg(-1)) performed five randomly ordered constant velocity tests (CVT), a maximal velocity test (mean velocity over the last 10 m portion of a 40 m sprint) and a 800 m time trial (V 800 m). Five systems models (two three-parameter and three two-parameter) were used to compute V max (three-parameter models), critical velocity (CV), anaerobic running capacity (ARC) and V800m from times to exhaustion during CVT. Vmax estimates were significantly lower than (0.19
NASA Astrophysics Data System (ADS)
Wu, Cheng-Feng; Huang, Huey-Chu
2012-05-01
The September 21, 1999, Chi-Chi earthquake induced strong shaking, resulting in severe damage in the Puli area. According to Huang and Tarng (2005), the collapse of many structures during the earthquake was very closely related to site effects. Shallow shear-wave velocities are widely used for earthquake ground-motion site characterization. Thus, we investigate S-wave velocity structures for the Puli area by performing microtremor array measurements at 16 sites. Dispersion curves at these sites are calculated using the F-K method (Capon, 1969) for the vertical component; S-wave velocity structures for the Puli area are then estimated by surface wave inversion (Herrmann, 1991). If the S-wave velocity of the bedrock is assumed to be 2000 m/s, the depths of the Quaternary sediments in the Puli area are between 300 m (FAL, PIP) and 870 m (DAH). Moreover, there are 3˜6 distinct interfaces in the shallow velocity structure (0˜1000 m). The depth of the bedrock gradually increases from the edge (SIN, PIP) to the center (PUL, DAH) of the basin and the thickest Quaternary sediments appear near Heng-Chih-Cheng (DAH).
NASA Astrophysics Data System (ADS)
Moramarco, Tommaso; Alimenti, Federico; Zucco, Graziano; Barbetta, Silvia; Tarpanelli, Angelica; Brocca, Luca; Mezzanotte, Paolo; Rosselli, Luca; Orecchini, Giulia; Virili, Marco; Valigi, Paolo; Ciarfuglia, Thomas; Pagnottelli, Stefano
2015-04-01
Discharge estimation at a river site depends on local hydraulic conditions identified by recording water levels. In fact, stage monitoring is straightforward and relatively inexpensive compared with the cost necessary to carry out flow velocity measurements which are, however, limited to low flows and constrained by the accessibility of the site. In this context the mean flow velocity is hard to estimate for high flow, affecting de-facto the reliability of discharge assessment for extreme events. On the other hand, the surface flow velocity can be easily monitored by using radar sensors allowing to achieve a good estimate of discharge by exploiting the entropy theory applied to rivers hydraulic (Chiu,1987). Recently, a growing interest towards the use of Unmanned Aerial Vehicle (UVA), henceforth drone, for topographic applications is observed and considering their capability drones may be of a considerable interest for the hydrological monitoring and in particular for streamflow measurements. With this aim, for the first time, a miniaturized Doppler radar sensor, operating at 24 GHz, will be mounted on a drone to measure the surface flow velocity in rivers. The sensor is constituted by a single-board circuit (i.e. is a fully planar circuits - no waveguides) with the antenna on one side and the front-end electronic on the other side (Alimenti et al., 2007). The antenna has a half-power beam width of less than 10 degrees in the elevation plane and a gain of 13 dBi. The radar is equipped with a monolithic oscillator and transmits a power of about 4 mW at 24 GHz. The sensor is mounted with an inclination of 45 degrees with respect to the drone flying plane and such an angle is considered in recovering the surface speed of the water. The drone is a quadricopter that has more than 30 min, flying time before recharging the battery. Furthermore its flying plan can be scheduled with a suitable software and is executed thanks to the on-board sensors (GPS, accelerometers
Sugiura, Yoshito; Hatanaka, Yasuhiko; Arai, Tomoaki; Sakurai, Hiroaki; Kanada, Yoshikiyo
2016-04-01
We aimed to investigate whether a linear regression formula based on the relationship between joint torque and angular velocity measured using a high-speed video camera and image measurement software is effective for estimating 1 repetition maximum (1RM) and isometric peak torque in knee extension. Subjects comprised 20 healthy men (mean ± SD; age, 27.4 ± 4.9 years; height, 170.3 ± 4.4 cm; and body weight, 66.1 ± 10.9 kg). The exercise load ranged from 40% to 150% 1RM. Peak angular velocity (PAV) and peak torque were used to estimate 1RM and isometric peak torque. To elucidate the relationship between force and velocity in knee extension, the relationship between the relative proportion of 1RM (% 1RM) and PAV was examined using simple regression analysis. The concordance rate between the estimated value and actual measurement of 1RM and isometric peak torque was examined using intraclass correlation coefficients (ICCs). Reliability of the regression line of PAV and % 1RM was 0.95. The concordance rate between the actual measurement and estimated value of 1RM resulted in an ICC(2,1) of 0.93 and that of isometric peak torque had an ICC(2,1) of 0.87 and 0.86 for 6 and 3 levels of load, respectively. Our method for estimating 1RM was effective for decreasing the measurement time and reducing patients' burden. Additionally, isometric peak torque can be estimated using 3 levels of load, as we obtained the same results as those reported previously. We plan to expand the range of subjects and examine the generalizability of our results.
Sugiura, Yoshito; Hatanaka, Yasuhiko; Arai, Tomoaki; Sakurai, Hiroaki; Kanada, Yoshikiyo
2016-04-01
We aimed to investigate whether a linear regression formula based on the relationship between joint torque and angular velocity measured using a high-speed video camera and image measurement software is effective for estimating 1 repetition maximum (1RM) and isometric peak torque in knee extension. Subjects comprised 20 healthy men (mean ± SD; age, 27.4 ± 4.9 years; height, 170.3 ± 4.4 cm; and body weight, 66.1 ± 10.9 kg). The exercise load ranged from 40% to 150% 1RM. Peak angular velocity (PAV) and peak torque were used to estimate 1RM and isometric peak torque. To elucidate the relationship between force and velocity in knee extension, the relationship between the relative proportion of 1RM (% 1RM) and PAV was examined using simple regression analysis. The concordance rate between the estimated value and actual measurement of 1RM and isometric peak torque was examined using intraclass correlation coefficients (ICCs). Reliability of the regression line of PAV and % 1RM was 0.95. The concordance rate between the actual measurement and estimated value of 1RM resulted in an ICC(2,1) of 0.93 and that of isometric peak torque had an ICC(2,1) of 0.87 and 0.86 for 6 and 3 levels of load, respectively. Our method for estimating 1RM was effective for decreasing the measurement time and reducing patients' burden. Additionally, isometric peak torque can be estimated using 3 levels of load, as we obtained the same results as those reported previously. We plan to expand the range of subjects and examine the generalizability of our results. PMID:26382131
The covariance between hourly concentration (C) and deposition velocity (V) for various atmospheric; species may act to bias the, deposition (D) computed from the product of the weekly average C and 'V. This is a potential problem for the CASTNet filter pack (FP) species, nitric ...
The covariance between hourly concentration (C) and deposition velocity (V) for various atmospheric; species may act to bias the, deposition (D) computed from the product of the weekly average C and 'V. This is a potential problem for the CASTNet filter pack (FP) species, nitric...
A simple method to estimate threshold friction velocity of wind erosion in the field
Technology Transfer Automated Retrieval System (TEKTRAN)
Nearly all wind erosion models require the specification of threshold friction velocity (TFV). Yet determining TFV of wind erosion in field conditions is difficult as it depends on both soil characteristics and distribution of vegetation or other roughness elements. While several reliable methods ha...
Estimates of black hole natal kick velocities from observations of low-mass X-ray binaries
NASA Astrophysics Data System (ADS)
Mandel, Ilya
2016-02-01
The birth kicks of black holes, arising from asymmetric mass ejection or neutrino emission during core-collapse supernovae, are of great interest for both observationally constraining supernova models and population-synthesis studies of binary evolution. Recently, several efforts were undertaken to estimate black hole birth kicks from observations of black hole low-mass X-ray binaries. We follow up on this work, specifically focusing on the highest estimated black hole kick velocities. We find that existing observations do not require black hole birth kicks in excess of approximately 80 km s-1, although higher kicks are not ruled out.
NASA Astrophysics Data System (ADS)
Lontsi, A. M.; Ohrnberger, M.; Krüger, F.
2016-07-01
We present an integrated approach for deriving the 1D shear wave velocity (Vs) information at few tens to hundreds of meters down to the first strong impedance contrast in typical sedimentary environments. We use multiple small aperture seismic arrays in 1D and 2D configuration to record active and passive seismic surface wave data at two selected geotechnical sites in Germany (Horstwalde & Löbnitz). Standard methods for data processing include the Multichannel Analysis of Surface Waves (MASW) method that exploits the high frequency content in the active data and the sliding window frequency-wavenumber (f-k) as well as the spatial autocorrelation (SPAC) methods that exploit the low frequency content in passive seismic data. Applied individually, each of the passive methods might be influenced by any source directivity in the noise wavefield. The advantages of active shot data (known source location) and passive microtremor (low frequency content) recording may be combined using a correlation based approach applied to the passive data in the so called Interferometric Multichannel Analysis of Surface Waves (IMASW). In this study, we apply those methods to jointly determine and interpret the dispersion characteristics of surface waves recorded at Horstwalde and Löbnitz. The reliability of the dispersion curves is controlled by applying strict limits on the interpretable range of wavelengths in the analysis and further avoiding potentially biased phase velocity estimates from the passive f-k method by comparing to those derived from the SPatial AutoCorrelation method (SPAC). From our investigation at these two sites, the joint analysis as proposed allows mode extraction in a wide frequency range (~ 0.6-35 Hz at Horstwalde and ~ 1.5-25 Hz at Löbnitz) and consequently improves the Vs profile inversion. To obtain the shear wave velocity profiles, we make use of a global inversion approach based on the neighborhood algorithm to invert the interpreted branches of the
Estimating time to contact and impact velocity when catching an accelerating object with the hand.
Senot, Patrice; Prévost, Pascal; McIntyre, Joseph
2003-02-01
To catch a moving object with the hand requires precise coordination between visual information about the target's motion and the muscle activity necessary to prepare for the impact. A key question remains open as to if and how a human observer uses velocity and acceleration information when controlling muscles in anticipation of impact. Participants were asked to catch the moving end of a swinging counterweighted pendulum, and resulting muscle activities in the arm were measured. The authors also simulated muscle activities that would be produced according to different tuning strategies. By comparing data with simulations, the authors provide evidence that human observers use online information about velocity but not acceleration when preparing for impact.
Cantwell, C.D.; Roney, C.H.; Ng, F.S.; Siggers, J.H.; Sherwin, S.J.; Peters, N.S.
2015-01-01
Measurements of cardiac conduction velocity provide valuable functional and structural insight into the initiation and perpetuation of cardiac arrhythmias, in both a clinical and laboratory context. The interpretation of activation wavefronts and their propagation can identify mechanistic properties of a broad range of electrophysiological pathologies. However, the sparsity, distribution and uncertainty of recorded data make accurate conduction velocity calculation difficult. A wide range of mathematical approaches have been proposed for addressing this challenge, often targeted towards specific data modalities, species or recording environments. Many of these algorithms require identification of activation times from electrogram recordings which themselves may have complex morphology or low signal-to-noise ratio. This paper surveys algorithms designed for identifying local activation times and computing conduction direction and speed. Their suitability for use in different recording contexts and applications is assessed. PMID:25978869
Brandão, Eric; Flesch, Rodolfo C C; Lenzi, Arcanjo; Flesch, Carlos A
2011-07-01
The pressure-particle velocity (PU) impedance measurement technique is an experimental method used to measure the surface impedance and the absorption coefficient of acoustic samples in situ or under free-field conditions. In this paper, the measurement uncertainty of the the absorption coefficient determined using the PU technique is explored applying the Monte Carlo method. It is shown that because of the uncertainty, it is particularly difficult to measure samples with low absorption and that difficulties associated with the localization of the acoustic centers of the sound source and the PU sensor affect the quality of the measurement roughly to the same extent as the errors in the transfer function between pressure and particle velocity do.
NASA Astrophysics Data System (ADS)
Mauldin, A.; Schlosser, P.; Newton, R.; Smethie, W. M.; Bayer, R.; Rhein, M.; Jones, E. Peter
2010-08-01
The Arctic Ocean Boundary Current (AOBC) is a persistent, large-scale feature of Arctic circulation that transports water of Atlantic origin around the Eurasian and Canadian Basins. Despite its importance as a link between North Atlantic sea surface temperature and the heat budget of the Arctic Ocean, elements of the pathways of the AOBC are still not well understood. Here we use transient tracer data collected during the 1990s at 22 locations to calculate the velocity and mixing time scale of the AOBC. The apparent spreading velocity derived from correlating 3H-3He ages in the Barents Sea branch water (BSBW) with the distance from its entry point at the Santa Anna Trough is 0.9 cm s-1. To correct this apparent velocity for the effects of mixing along the pathway, the AOBC is modeled as a leaky pipe, and 3H-3He and chlorofluorocarbon data are used to calculate the parameters of its transit time distribution function. The modeled velocity of the AOBC is 2.5 ± 0.5 cm s-1, and the time scale for mixing of waters between the core of the boundary current and the adjacent water masses is 5-10 years. These results imply that the advective time for transport around the perimeter of the Arctic Ocean from the Santa Anna Trough to the southern Canada Basin (approximately 6000 km) is 7.5 years, and the amplitude of a temperature anomaly or salinity anomaly in BSBW should decrease by 50%-75% along this path.
Lou, Z; Yang, W J; Stein, P D
1993-01-01
An analysis was performed to determine the error that results from the estimation of the wall shear rates based on linear and quadratic curve-fittings of the measured velocity profiles. For steady, fully developed flow in a straight vessel, the error for the linear method is linearly related to the distance between the probe and the wall, dr1, and the error for the quadratic method is zero. With pulsatile flow, especially a physiological pulsatile flow in a large artery, the thickness of the velocity boundary layer, delta is small, and the error in the estimation of wall shear based on curve fitting is much higher than that with steady flow. In addition, there is a phase lag between the actual shear rate and the measured one. In oscillatory flow, the error increases with the distance ratio dr1/delta and, for a quadratic method, also with the distance ratio dr2/dr1, where dr2 is the distance of the second probe from the wall. The quadratic method has a distinct advantage in accuracy over the linear method when dr1/delta < 1, i.e. when the first velocity point is well within the boundary layer. The use of this analysis in arterial flow involves many simplifications, including Newtonian fluid, rigid walls, and the linear summation of the harmonic components, and can provide more qualitative than quantitative guidance. PMID:8478343
Pidlisecky, A.; Haines, S.S.
2011-01-01
Conventional processing methods for seismic cone penetrometer data present several shortcomings, most notably the absence of a robust velocity model uncertainty estimate. We propose a new seismic cone penetrometer testing (SCPT) data-processing approach that employs Bayesian methods to map measured data errors into quantitative estimates of model uncertainty. We first calculate travel-time differences for all permutations of seismic trace pairs. That is, we cross-correlate each trace at each measurement location with every trace at every other measurement location to determine travel-time differences that are not biased by the choice of any particular reference trace and to thoroughly characterize data error. We calculate a forward operator that accounts for the different ray paths for each measurement location, including refraction at layer boundaries. We then use a Bayesian inversion scheme to obtain the most likely slowness (the reciprocal of velocity) and a distribution of probable slowness values for each model layer. The result is a velocity model that is based on correct ray paths, with uncertainty bounds that are based on the data error. ?? NRC Research Press 2011.
Hubble Space Telescope Angular Velocity Estimation During the Robotic Servicing Mission
NASA Technical Reports Server (NTRS)
Thienel, Julie K.; Sanner, Robert M.
2005-01-01
In 2004 NASA began investigation of a robotic servicing mission for the Hubble Space Telescope (HST). Such a mission would require estimates of the HST attitude and rates in order to achieve a capture by the proposed Hubble robotic vehicle (HRV). HRV was to be equipped with vision-based sensors, capable of estimating the relative attitude between HST and HRV. The inertial HST attitude is derived from the measured relative attitude and the HRV computed inertial attitude. However, the relative rate between HST and HRV cannot be measured directly. Therefore, the HST rate with respect to inertial space is not known. Two approaches are developed to estimate the HST rates. Both methods utilize the measured relative attitude and the HRV inertial attitude and rates. First, a nonlinear estimator is developed. The nonlinear approach estimates the HST rate through an estimation of the inertial angular momentum. The development includes an analysis of the estimator stability given errors in the measured attitude. Second, a linearized approach is developed. The linearized approach is a pseudo-linear Kalman filter. Simulation test results for both methods are given, including scenarios with erroneous measured attitudes. Even though the development began as an application for the HST robotic servicing mission, the methods presented are applicable to any rendezvous/capture mission involving a non-cooperative target spacecraft.
Probabilistic estimates of maximum acceleration and velocity in rock in the contiguous United States
Algermissen, Sylvester Theodore; Perkins, D.M.; Thenhaus, P.C.; Hanson, S.L.; Bender, B.L.
1982-01-01
Maximum horizontal accelerations and velocities caused by earthquakes are mapped for exposure times of 10, 50 and 250 years at the 90-percent probability level of nonexceedance for the contiguous United States. In many areas these new maps differ significantly from the 1976 probabilistic acceleration map by Algermlssen and Perkins because of the increase in detail, resulting from greater emphasis on the geologic basis for seismic source zones. This new emphasis is possible because of extensive data recently acquired on Holocene and Quaternary faulting in the western United States and new interpretations of geologic structures controlling the seismicity pattern in the central and eastern United States.
Napier, Bruce A.; Rishel, Jeremy P.; Cook, Kary M.
2013-09-12
Values for the dry deposition velocity of airborne particles were estimated with the GENII Version 2.10.1 computer code for the Savannah River site using assumptions about surface roughness parameters and particle size and density. Use of the GENII code is recommended by the U.S. Department of Energy for this purpose. Meteorological conditions evaluated include atmospheric stability classes D, E, and F and wind speeds of 0.5, 1.0, 1.5, and 2.0 m/s. Local surface roughness values ranging from 0.03 to 2 meters were evaluated. Particles with mass mean diameters of 1, 5, and 10 microns and densities of 1, 3, 4, and 5 g/cm3 were evaluated. Site specific meteorology was used to predict deposition velocity for Savannah River conditions for a range of distances from 670 to 11,500 meters.
Hubble Space Telescope Angular Velocity Estimation During the Robotic Servicing Mission
NASA Technical Reports Server (NTRS)
Thienel, Julie K.; Queen, Steven Z.; VanEepoel, John M.; Sanner, Robert M.
2005-01-01
In 2004 NASA began investigation of a robotic servicing mission for the Hubble Space Telescope (HST). Such a mission would require estimates of the HST attitude and rates in order to achieve a capture by the proposed Hubble robotic vehicle (HRV). HRV was to be equipped with vision-based sensors, capable of estimating the relative attitude between HST and HRV. The inertial HST attitude is derived from the measured relative attitude and the HRV computed inertial attitude. However, the relative rate between HST and HRV cannot be measured directly. Therefore, the HST rate with respect to inertial space is not known. Two approaches are developed to estimate the HST rates. Both methods utilize the measured relative attitude and the HRV inertial attitude and rates. First, a non-linear estimator is developed. The nonlinear approach estimates the HST rate through an estimation of the inertial angular momentum. Second, a linearized approach is developed. The linearized approach is a pseudo-linear Kalman filter. Simulation test results for both methods are given. Even though the development began as an application for the HST robotic servicing mission, the methods presented are applicable to any rendezvous/capture mission involving a non-cooperative target spacecraft.
Hubble Space Telescope Angular Velocity Estimation During the Robotic Servicing Mission
NASA Technical Reports Server (NTRS)
Thienel, Julie K.; Queen, Steven Z.; VanEepoel, John M.; Sanner, Robert M.
2005-01-01
During the Hubble Robotic Servicing Mission, the Hubble Space Telescope (HST) attitude and rates are necessary to achieve the capture of HST by the Hubble Robotic Vehicle (HRV). The attitude and rates must be determined without the HST gyros or HST attitude estimates. The HRV will be equipped with vision-based sensors, capable of estimating the relative attitude between HST and HRV. The HST attitude is derived from the measured relative attitude and the HRV computed inertial attitude. However, the relative rate between HST and HRV cannot be measured directly. Therefore, the HST rate with respect to inertial space is not known. Two approaches are developed to estimate the HST rates. Both methods utilize the measured relative attitude and the HRV inertial attitude and rates. First, a nonlinear estimator is developed. The nonlinear approach estimates the HST rate through an estimation of the inertial angular momentum. Second, a linearized approach is developed. The linearized approach is based on more traditional Extended Kalman filter techniques. Simulation test results for both methods are given.
Estimation of neutral wind velocity in the ionospheric heights by HF-Doppler technique
NASA Technical Reports Server (NTRS)
Kitamura, T.; Takefu, M.; Hiroshige, N.
1985-01-01
Three net stations located about 100 kilometers apart were set up around the station of the standard frequency and time signals (JJY) in central Japan and measurements of atmospheric gravity waves in the ionospheric heights (F-region, 200 to 400 km) were made by means of the HF-Doppler technique during the period of February 1983 to December 1983. The frequencies of the signals received are 5.0, 8.0 and 10.0 MHz, but only the 8.0 MHz signals are used for the present study, because no ambiguities due to the interference among other stations such as BPM, BSF, etc. exist by the use of 8.0 MHz. Two main results concerning the horizontal phase velocity of the atmospheric gravity waves with periods of 40 to 70 min may be summarized as follows: (1) the value of the phase velocity ranges from 50 m/s to 300 m/s; (2) the direction of the gravity wave propagation shows a definite seasonal variation. The prevailing direction of the gravity waves in winter is from north to south, which is consistent with the results obtained from other investigations. On the other hand, the two directions, from northeast to southwest and from southeast to northeast, dominate in summer.
NASA Astrophysics Data System (ADS)
Jiang, L.; Sun, Y.; Liu, L.; Wang, S.; Wang, H.
2014-12-01
In many cases the Landsat mission series (Landsat 1-5, 7 and 8) provide our only detailed and consistent data source for mapping the global glacier changes over the last 40 years. However, the scan-line corrector (SLC) of the ETM+ sensor on board Landsat 7 permanently failed, resulting in wedge-shaped data gaps in SLC-off images that caused roughly 22% of the pixels to be missed. The SLC failure has left a serious problem for the glacial applications of ETM+ data, particularly for monitoring long-term glacier dynamics in High Asian Mountain where has few available data due to the frequently cloudy covers. This study aims to evaluate the potential of the Landsat 7 SLC-off images in deriving surface velocities of mountain glaciers. A pair of SLC-off images over the Siachen glacier acquired in Aug 2009 and 2010 was used for this purpose. Firstly, two typical filling-gap methods, the localized linear histogram match (LLHM) and the weighted liner regression (WLR), were utilized to recover the mentioned SLC-off images. Subsequently these recovered pairs were applied for deriving glacier-surface velocities with the COSI-Corr feature tracking procedure. Finally, the glacier velocity results were quantitatively compared with that of a pair of Landsat-5 TM images acquired nearly at the same time with the SLC-off pair. Our results show that (1) the WLR method achieves a better performance of gap recovering than the LLHM method, (2) the surface velocities estimated with the recovered SLC-off images are highly agreement with those of the TM images, and (3) the annual mean velocity of the Siachen glacier is approximately 70 m/yr between 2009 and 2010 with a maximum of 280 m/yr close to the glacial equilibrium line that are similar with the results in previous studies. Therefore, if a suitable filling-gap method is adopted, e.g. the WLR method, it is highly feasible that the ETM+ SLC-off data can be utilized to estimate the surface velocities of mountain glaciers.
NASA Astrophysics Data System (ADS)
Hackl, M.; Malservisi, R.; Hugentobler, U.; Wonnacott, R.
2011-11-01
We present a method to derive velocity uncertainties from GPS position time series that are affected by time-correlated noise. This method is based on the Allan variance, which is widely used in the estimation of oscillator stability and requires neither spectral analysis nor maximum likelihood estimation (MLE). The Allan variance of the rate (AVR) is calculated in the time domain and hence is not too sensitive to gaps in the time series. We derived analytical expressions of the AVR for different kinds of noises like power law noise, white noise, flicker noise, and random walk and found an expression for the variance produced by an annual signal. These functional relations form the basis of error models that have to be fitted to the AVR in order to estimate the velocity uncertainty. Finally, we applied the method to the South Africa GPS network TrigNet. Most time series show noise characteristics that can be modeled by a power law noise plus an annual signal. The method is computationally very cheap, and the results are in good agreement with the ones obtained by methods based on MLE.
Comparisons of Crosswind Velocity Profile Estimates Used in Fast-Time Wake Vortex Prediction Models
NASA Technical Reports Server (NTRS)
Pruis, Mathew J.; Delisi, Donald P.; Ahmad, Nashat N.
2011-01-01
Five methods for estimating crosswind profiles used in fast-time wake vortex prediction models are compared in this study. Previous investigations have shown that temporal and spatial variations in the crosswind vertical profile have a large impact on the transport and time evolution of the trailing vortex pair. The most important crosswind parameters are the magnitude of the crosswind and the gradient in the crosswind shear. It is known that pulsed and continuous wave lidar measurements can provide good estimates of the wind profile in the vicinity of airports. In this study comparisons are made between estimates of the crosswind profiles from a priori information on the trajectory of the vortex pair as well as crosswind profiles derived from different sensors and a regional numerical weather prediction model.
Nam, Kyung-Tae; Lee, Seung-Joon; Kuc, Tae-Yong; Kim, Hyungjong
2015-01-01
In this paper, we consider the state estimation problem for flexible joint manipulators that involve nonlinear characteristics in their stiffness. The two key ideas of our design are that (a) an accelerometer is used in order that the estimation error dynamics do not depend on nonlinearities at the link part of the manipulators and (b) the model of the nonlinear stiffness is indeed a Lipschitz function. Based on the measured acceleration, we propose a nonlinear observer under the Lipschitz condition of the nonlinear stiffness. In addition, in order to effectively compensate for the estimation error, the gain of the proposed observer is chosen from the ARE (algebraic Riccati equations) which depend on the Lipschitz constant. Comparative experimental results verify the effectiveness of the proposed method. PMID:26729125
Nam, Kyung-Tae; Lee, Seung-Joon; Kuc, Tae-Yong; Kim, Hyungjong
2015-01-01
In this paper, we consider the state estimation problem for flexible joint manipulators that involve nonlinear characteristics in their stiffness. The two key ideas of our design are that (a) an accelerometer is used in order that the estimation error dynamics do not depend on nonlinearities at the link part of the manipulators and (b) the model of the nonlinear stiffness is indeed a Lipschitz function. Based on the measured acceleration, we propose a nonlinear observer under the Lipschitz condition of the nonlinear stiffness. In addition, in order to effectively compensate for the estimation error, the gain of the proposed observer is chosen from the ARE (algebraic Riccati equations) which depend on the Lipschitz constant. Comparative experimental results verify the effectiveness of the proposed method.
A new device for estimating active drag in swimming at maximal velocity.
Xin-Feng, Wang; Lian-Ze, Wang; Wei-Xing, Yan; De-Jian, Li; Xiong, Shen
2007-02-15
A new device was designed to measure the active drag during maximal velocity swimming based on the assumption of equal useful power output in two cases: with and without a small additional drag. A gliding block was used to provide an adjustable drag, which was attached to the swimmer and measured by a force transducer. Six swimmers of national standard (3 males, 3 females) participated in the test. For the males, the mean active drag ranged from 48.57 to 105.88 N in the front crawl and from 54.14 to 76.37 N in the breaststroke. For the females, the mean active drag ranged from 36.31 to 50.27 N in the front crawl and from 36.25 to 77.01 N in the breaststroke. During testing, the swimmer's natural stroke and kick were not disturbed. We conclude that the device provides a useful method for measuring and studying active drag.
NASA Astrophysics Data System (ADS)
Feng, H. S.; Lizarralde, D.
2012-12-01
sediments from the same stratal units that are undisturbed at one location and disturbed by intruded sills at a nearby location. We target a number of such pairs and compare the seismic properties of altered and unaltered sediments. We estimate the seismic velocity of sedimentary sequences by modeling reflection travel times. Our travel-time analyses show an increase in bulk velocity of ~10% for altered sediments located above sills versus unaltered sediments from the same stratal units, and waveform inversions provide detailed velocity changes. These velocity models are used to estimate porosity change, and porosity change is used as a proxy for alteration intensity. DSDP Leg 64 cores suggest a relationship between porosity reduction and carbon loss, and we assess the ability of the velocity models to estimate carbon loss based on alteration intensity. This approach may provide a cost effective means of estimating carbon release from altered sediments over a regionally extensive.
NASA Astrophysics Data System (ADS)
Despax, Aurélien; Perret, Christian; Garçon, Rémy; Hauet, Alexandre; Belleville, Arnaud; Le Coz, Jérôme; Favre, Anne-Catherine
2016-04-01
Quantifying the quality of discharge measurements by uncertainty analysis is a challenge in the hydrometric community. Discharge measurements are the first step to produce hydrometric data which are used in many hydrological studies like design of hydraulic structures or calibration of hydrological models for flood forecasting and warning. Thus associated uncertainty has to be estimated carefully. The velocity-area method is a common approach for estimating river discharge. It consists in integrating depths and point velocities through the cross-section. Due to the limited number of point measurements, the quality of the measurement depends mainly on the sampling strategy. Different methods of uncertainty estimation are available in the literature (ISO 748, Q+ and IVE). The main uncertainty component, noted um, is often related to the cross-sectional interpolation errors. However the computation of this term according to these approaches does not evaluate both the sampling strategy and the complexity of the cross-section. The FLAURE method (FLow Analog UnceRtainty Estimation) includes a new methodology to estimate this term. It is based on the study of high-resolution stream-gaugings (i.e. reference stream-gaugings made with a high number of verticals). The high-resolution measurements are first subsampled by reducing the number of verticals to generate a sample of realistic stream-gaugings. A statistical analysis is performed to estimate the um component and then a sampling quality index is defined. For each reference stream-gauging, it leads to a curve of um component as a function of the sampling quality index. This set of curves is finally used to compute the um component of any routine stream-gauging. Curves are then selected according to the similitude between the routine stream-gauging and reference stream-gaugings. The similitude between the routine stream-gauging and reference stream-gaugings is evaluated thanks to the Nash criteria computed on lateral
Mesin, Luca; Tizzani, Francesca; Farina, Dario
2006-10-01
Muscle fiber conduction velocity (CV) can be estimated by the application of a pair of spatial filters to surface electromagnetic (EMG) signals and compensation of the spatial filter transfer function with equivalent temporal filters. This method integrates the selection of the spatial filters for signal detection to the estimation of CV. Using this approach, in this paper, we propose a novel technique for signal-based selection of the spatial filter pair that minimizes the effect of nonpropagating signal components (end-of-fiber effects) on CV estimates (optimal filters). The technique is applicable to signals with one propagating and one nonpropagating component, such as single motor unit action potentials. It is shown that the determination of the optimal filters also allows the identification of the propagating and nonpropagating signal components. The new method was applied to simulated and experimental EMG signals. Simulated signals were generated by a cylindrical, layered volume conductor model. Experimental signals were recorded from the abductor pollicis brevis with a linear array of 16 electrodes. In the simulations, the proposed approach provided CV estimates with lower bias due to nonpropagating signal components than previously proposed methods based on the entire signal waveform. In the experimental signals, the technique separated propagating and nonpropagating signal components with an average reconstruction error of 2.9 +/- 0.9% of the signal energy. The technique may find application in single motor unit studies for decreasing the variability and bias of CV estimates due to the presence and different weights of the nonpropagating components.
Camargo-Junior, Franklin; Ackermann, Marko; Loss, Jefferson F; Sacco, Isabel C N
2013-12-01
The aim of this study was to investigate the effect of errors in the location of the center of pressure (5 and 10 mm) on lower limb joint moment uncertainties at different gait velocities (1.0, 1.5, and 2.0 m/s). Our hypotheses were that the absolute joint moment uncertainties would be gradually reduced from distal to proximal joints and from higher to lower velocities. Joint moments of five healthy young adults were calculated by inverse dynamics using the bottom-up approach, depending on which estimate the uncertainty propagated. Results indicated that there is a linear relationship between errors in center of pressure and joint moment uncertainties. The absolute moment peak uncertainties expressed on the anatomic reference frames decreased from distal to proximal joints, confirming our first hypothesis, except for the abduction moments. There was an increase in moment uncertainty (up to 0.04 N m/kg for the 10 mm error in the center of pressure) from the lower to higher gait velocity, confirming our second hypothesis, although, once again, not for hip or knee abduction. Finally, depending on the plane of movement and the joint, relative uncertainties experienced variation (between 5 and 31%), and the knee joint moments were the most affected.
Aoshima, H; Inoue, Y; Hori, K
1992-10-01
Since binding of an agonist to an ionotropic neurotransmitter receptor causes not only channel opening, but also desensitization of the receptor, inhibition of the receptor by the antagonist sometimes becomes very complicated. The transient state kinetics of ligand association and dissociation, and desensitization of the receptor were considered on the basis of the minimal model proposed by Hess' group, and the following possibilities were proposed. 1) When an agonist is simultaneously applied to the receptor with an antagonist whose affinity to the receptor is extremely strong and different from that of the agonist, it is usually impossible to estimate the real inhibition constant exactly from the responses because desensitization of the receptor proceeds before the equilibrium of the ligand binding. Simultaneous addition of the antagonist with strong affinity to the receptor may apparently accelerate inactivation (desensitization) of the receptor. The association rate constant of the antagonist can be estimated by analyses of the rate of the inactivation in the presence and the absence of the antagonist. 2) A preincubated antagonist with a slow dissociation rate constant, i.e., a very effective inhibitor, may cause apparent noncompetitive inhibition of the receptor, since the receptor is desensitized by an agonist as soon as the antagonist dissociates from the receptor and the dissociation of the antagonist from the receptor becomes the rate-determining step. A nicotinic acetylcholine receptor (nAChR) was expressed in Xenopus oocytes by injecting mRNA prepared from Electrophorus electricus electroplax and used for the experiments on inhibition by an antagonist.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:1337082
Asymmetry of Drosophila ON and OFF motion detectors enhances real-world velocity estimation.
Leonhardt, Aljoscha; Ammer, Georg; Meier, Matthias; Serbe, Etienne; Bahl, Armin; Borst, Alexander
2016-05-01
The reliable estimation of motion across varied surroundings represents a survival-critical task for sighted animals. How neural circuits have adapted to the particular demands of natural environments, however, is not well understood. We explored this question in the visual system of Drosophila melanogaster. Here, as in many mammalian retinas, motion is computed in parallel streams for brightness increments (ON) and decrements (OFF). When genetically isolated, ON and OFF pathways proved equally capable of accurately matching walking responses to realistic motion. To our surprise, detailed characterization of their functional tuning properties through in vivo calcium imaging and electrophysiology revealed stark differences in temporal tuning between ON and OFF channels. We trained an in silico motion estimation model on natural scenes and discovered that our optimized detector exhibited differences similar to those of the biological system. Thus, functional ON-OFF asymmetries in fly visual circuitry may reflect ON-OFF asymmetries in natural environments.
Vrba; Simek; Pernthaler; Psenner
1996-07-01
Protistan community grazing rates upon both bacterioplankton and autotrophic picoplankton were estimated using fluorescently-labeled prey and by measurement of extracellular hydrolysis of 4-methylumbelliferyl (MUF) beta-N-acetylglucosaminide in a eutrophic reservoir and an oligo-mesotrophic lake during phytoplankton blooms. In addition, enzyme methods were optimized in bacterivorous flagellate cultures by two enzyme assays, based on fluorometric detection of protistan digestive activity, which were compared and calibrated independently against flagellate bacterivory. Enzymatic hydrolyses of MUF beta-N,N',N''-triacetylchitotriose and MUF beta-N-acetylglucosaminide were measured in cell-free (sonicated) and whole-cell (unsonicated) samples. The hydrolysis of both substrates, using the whole-cell enzyme assay at in situ pH, was correlated significantly with total grazing rate of Bodo saltans. Thus the whole-cell enzyme assay with MUF beta-N-acetylglucosaminide was used for freshwater samples. High-affinity (Km < 1 μmol l-1) and low-affinity (Km > 100μmol l-1) enzymes were distinguished kinetically in most samples from both systems studied. Activities (Vmax) of the high-affinity enzyme varied from 0.24 to 1.43 nmol l-1 h-1. Protistan community grazing on bacterioplankton was in the range of 0.15-1.36 μg C l-1 h-1 both for lake and reservoir, the differences being observed in grazing on picocyanobacteria (lake, 0.03-0.22 μg C l-1 h-1; reservoir, 0.35-1.56 μg C l-1 h-1). The enzyme activities were correlated significantly with the protistan grazing both on bacterioplakton (rs=0.62, P<0.001) and total procaryotic picoplankton (the sum of organic carbon grazed from bacteria and picocyanobacteria, rs=0.73, P<0.001) in the eutrophic reservoir. Weaker relationships (rs=0.42) with a lower slope were found for the oligo-mesotrophic lake. Ingestion rate studies are time-consuming and the digestive enzyme assay with MUF beta-N-acetylglucosaminide presents a rapid alternative
Xia, J.; Xu, Y.; Miller, R.D.; Chen, C.
2006-01-01
A Gibson half-space model (a non-layered Earth model) has the shear modulus varying linearly with depth in an inhomogeneous elastic half-space. In a half-space of sedimentary granular soil under a geostatic state of initial stress, the density and the Poisson's ratio do not vary considerably with depth. In such an Earth body, the dynamic shear modulus is the parameter that mainly affects the dispersion of propagating waves. We have estimated shear-wave velocities in the compressible Gibson half-space by inverting Rayleigh-wave phase velocities. An analytical dispersion law of Rayleigh-type waves in a compressible Gibson half-space is given in an algebraic form, which makes our inversion process extremely simple and fast. The convergence of the weighted damping solution is guaranteed through selection of the damping factor using the Levenberg-Marquardt method. Calculation efficiency is achieved by reconstructing a weighted damping solution using singular value decomposition techniques. The main advantage of this algorithm is that only three parameters define the compressible Gibson half-space model. Theoretically, to determine the model by the inversion, only three Rayleigh-wave phase velocities at different frequencies are required. This is useful in practice where Rayleigh-wave energy is only developed in a limited frequency range or at certain frequencies as data acquired at manmade structures such as dams and levees. Two real examples are presented and verified by borehole S-wave velocity measurements. The results of these real examples are also compared with the results of the layered-Earth model. ?? Springer 2006.
NASA Astrophysics Data System (ADS)
Rahman, Md. Zillur; Siddiqua, Sumi; Kamal, A. S. M. Maksud
2016-11-01
The average shear wave velocity of the near-surface materials down to a depth of 30 m (Vs30) is essential for seismic site characterization to estimate the local amplification factor of the seismic waves during an earthquake. Chittagong City is one of the highest risk cities of Bangladesh for its seismic vulnerability. In the present study, the Vs30 is estimated for Chittagong City using the multichannel analysis of surface waves (MASW), small scale microtremor measurement (SSMM), downhole seismic (DS), and correlation between the shear wave velocity (Vs) and standard penetration test blow count (SPT-N). The Vs30 of the near-surface materials of the city varies from 123 m/s to 420 m/s. A Vs30 map is prepared from the Vs30 of each 30 m grid using the relationship between the Holocene soil thickness and the Vs30. Based on the Vs30, the near-surface materials of Chittagong City are classified as site classes C, D, and E according to the National Earthquake Hazards Reduction Program (NEHRP), USA and as site classes B, C, and D according to the Eurocode 8. The Vs30 map can be used for seismic microzonation, future planning, and development of the city to improve the earthquake resiliency of the city.
Glauser, Gaetan; Dubugnon, Lucie; Mousavi, Seyed A. R.; Rudaz, Serge; Wolfender, Jean-Luc; Farmer, Edward E.
2009-01-01
The wound response prohormone jasmonic acid (JA) accumulates rapidly in tissues both proximal and distal to injury sites in plants. Using quantitative liquid chromatography-mass spectrometry after flash freezing of tissues, we found that JA accumulated within 30 s of injury in wounded Arabidopsis leaves (p = 3.5 e−7). JA augmentation distal to wounds was strongest in unwounded leaves with direct vascular connections to wounded leaves wherein JA levels increased significantly within 120 s of wounding (p = 0.00027). This gave conservative and statistically robust temporal boundaries for the average velocity of the long distance signal leading to distal JA accumulation in unwounded leaves of 3.4–4.5 cm min−1. Like JA, transcripts of the JA synthesis gene LIPOXYGENASE2 (LOX2) and the jasmonate response gene JAZ10.3 also accumulated to higher levels in directly interconnected leaves than in indirectly connected leaves. JA accumulation in a lox2-1 mutant plant was initiated rapidly after wounding then slowed progressively compared with the wild type (WT). Despite this, JAZ10.3 expression in the two genotypes was similar. Free cyclopentenone jasmonate levels were similar in both resting WT and lox2-1. In contrast, bound cyclopentenone jasmonates (arabidopsides) were far lower in lox2-1 than in the WT. The major roles of LOX2 are to generate arabidopsides and the large levels of JA that accumulate proximal to the wound. LOX2 is not essential for some of the most rapid events elicited by wounding. PMID:19846562
NASA Astrophysics Data System (ADS)
Szuberla, Curt A. L.; Olson, John V.
2002-11-01
Upon the detection of an atmospheric infrasound signal, the problem of precisely estimating the signal's velocity (v) and direction-of-arrival (theta) arises. Multiple sources, multipath, medium anisotropies, and other propagation effects can all degrade precision; however, uncertainty in the estimates of v and theta is fundamentally governed by array geometry and the estimation of time delays across the array. Typically, as in the Comprehensive Test Ban Treaty Organzation Provisional Technical Secretariat (CTBTO/PTS) specification for data from infrasound stations, the Cramer-Rao lower bound is invoked to ascertain the uncertainties associated with v and theta. As this theoretical lower limit is often overly conservative, a more general, and useful, approach to calculate these uncertainties is developed. Examples of this uncertainty determination are presented for typical impulsive and continuous atmospheric infrasound signals received at arrays in Windless Bight, Antarctica and Fairbanks, Alaska. Since the determination of v and theta serves as primary input to any propogation model, it is critical that uncertainties in these estimates be addressed. As an extension of this work, an interactive graphical tool is constructed to assist in the analysis of performance bounds for arbitrary array geometries and signal characteristics.
Chemical evolution and estimated flow velocity of water in the Trinity Aquifer, south-central Texas
Jones, Sonya A.; Lee, Roger W.; Busby, John F.
1997-01-01
exchange between solid and aqueous phases. Lower permeable zone processes indicate sodium chloride dissolution, dedolomitization, and cation exchange. Ground-water-flow velocities determined from adjusted carbon-14 ages, calculated using NETPATH, for selected flowpaths in the middle and lower permeable zones were about 1.7 feet per year and less than about 4.4 feet per year, respectively.
NASA Astrophysics Data System (ADS)
Chelton, D. B.; Schlax, M. G.
2002-12-01
Jason-1 was launched on 7 December 2001 and the altimeter data record began on 15 January 2002. The Jason altimeter operated in phase with TOPEX/POSEIDON (T/P) for 7 months, sampling the same 10-day exact-repeat ground track 72 seconds ahead of T/P. On 15 August 2002, a series of maneuvers was initiated to shift T/P to a different 10-day exact-repeat orbit with ground tracks half way between the ground track pattern established during the first 10 years of the mission and continued with the Jason mission. The interleaved sampling pattern with evenly spaced ground tracks afforded by this coordinated tandem mission will enable scientific investigations that have not heretofore been possible. Examples include significant improvements in the understanding of the wavenumber-frequency spectral characteristics of sea surface height (SSH) variability and the effects of eddy Reynolds stresses on the slowly varying background currents. A prerequisite to such scientific studies is a quantitative assessment of the errors of SSH fields and geostrophic velocity estimates obtainable from the coordinated tandem T/P-Jason altimeter mission. The root mean squared (rms) errors of smoothed SSH fields constructed from the tandem dataset are more than a factor of two smaller than those obtainable from T/P or Jason data alone. The rms errors of each geostrophic velocity component estimated by the parallel-track method with this track spacing are larger than 80% of the signal standard deviation between latitudes 10° and 45°, even with residual orbit errors as small as 1 cm. With suitable along-track smoothing, the rms errors of crossover estimates of both geostrophic velocity components are smaller than 30% of the signal standard deviation between latitudes 5° and 60°. The quadrupling of the number of crossovers from the sampling pattern of the tandem T/P-Jason mission compared with what is obtained from a single altimeter will greatly enhance the ability to investigate eddy-mean flow
NASA Astrophysics Data System (ADS)
Kimata, F.; Ohota, Y.; Negishi, H.; Matsubara, M.
2004-12-01
Ohota et al. (2004) estimated the fault model of the 2001 Tokai slow slip event based on the re-processing GPS data comparing the ground deformation in 1997-2000. From their discussion, in the period of slow slip event, interplate coupling is tightly remained in the depth of 10-25 km in the plate boundary in the Tokai region. Forward slip consisting of slow slip event is ongoing with a rate of 3 cm/yr at the depth of 25-40 km in the plate boundary. The slow slip event fault locates outside of the 1944 Tonankai earthquake fault model by Tanioka and Satake (2002). It suggests that slow slip event is occurred outside of asperity area of historical large earthquakes along the Nankai Trough. Recently dense seismological network is constructed and seismic wave velocity structure are discussed with detail from the seismic wave tomography method (Matsubara et al.,2004; Kamiya and Kobayashi, 2004). According to their resolution, the low Vp and Vs layer is estimated in the 25-40 km depth of the plate boundary between the Philippine Sea plate and Eurasian plate in the Tokai region. Precisely we discus the location of low Vp and Vs layers, it is located upper part pf the plate boundary with width of 10km, which is corresponded to the lower continental crust..It is located just under northern area of Lake Hamana and Mikawa Bay. Kodaira et al.(2004), they conclude that high Vp/Vs ration distributed in subducting upper ocean crust around 30 km depth of the plate boundary is a occurrence mechanism of the 2001 Tokai slow slip event. From our research, the rate of Vp/Vs in upper part of the subducting oceanic crust is changing with the depth of the plate boundary. Until 25 km depth, velocities of P-wave and S-wave are not low, and the rate Vp/Vs is normal. At depth of 25 - 40 km, velocities of P-wave and S-wave are decreasing, and the rate Vp/Vs is increasing. The depth of high rate is correspond the slow slip fault estimated by Ohota et al.(2004) and hypocenters of unvolcanic low
Klenzing, J. H.; Earle, G. D.; Heelis, R. A.; Coley, W. R.
2009-05-15
The use of biased grids as energy filters for charged particles is common in satellite-borne instruments such as a planar retarding potential analyzer (RPA). Planar RPAs are currently flown on missions such as the Communications/Navigation Outage Forecast System and the Defense Meteorological Satellites Program to obtain estimates of geophysical parameters including ion velocity and temperature. It has been shown previously that the use of biased grids in such instruments creates a nonuniform potential in the grid plane, which leads to inherent errors in the inferred parameters. A simulation of ion interactions with various configurations of biased grids has been developed using a commercial finite-element analysis software package. Using a statistical approach, the simulation calculates collected flux from Maxwellian ion distributions with three-dimensional drift relative to the instrument. Perturbations in the performance of flight instrumentation relative to expectations from the idealized RPA flux equation are discussed. Both single grid and dual-grid systems are modeled to investigate design considerations. Relative errors in the inferred parameters for each geometry are characterized as functions of ion temperature and drift velocity.
Cameron, M.K.; Fomel, S.B.; Sethian, J.A.
2009-01-01
In the present work we derive and study a nonlinear elliptic PDE coming from the problem of estimation of sound speed inside the Earth. The physical setting of the PDE allows us to pose only a Cauchy problem, and hence is ill-posed. However we are still able to solve it numerically on a long enough time interval to be of practical use. We used two approaches. The first approach is a finite difference time-marching numerical scheme inspired by the Lax-Friedrichs method. The key features of this scheme is the Lax-Friedrichs averaging and the wide stencil in space. The second approach is a spectral Chebyshev method with truncated series. We show that our schemes work because of (1) the special input corresponding to a positive finite seismic velocity, (2) special initial conditions corresponding to the image rays, (3) the fact that our finite-difference scheme contains small error terms which damp the high harmonics; truncation of the Chebyshev series, and (4) the need to compute the solution only for a short interval of time. We test our numerical scheme on a collection of analytic examples and demonstrate a dramatic improvement in accuracy in the estimation of the sound speed inside the Earth in comparison with the conventional Dix inversion. Our test on the Marmousi example confirms the effectiveness of the proposed approach.
Over, T.M.; Duncker, J.J.; Gonzalez-Castro, J. A.; ,
2004-01-01
Estimates of uncertainty of discharge at time scales from 5 minutes to 1 year were obtained for two index-velocity gages on the Chicago Sanitary and Ship Canal (CSSC), Ill., instrumented with acoustic velocity meters (AVMs). The velocity measurements obtained from the AVMs are corrected to a mean channel velocity by use of an index velocity rating (IVR). The IVR is a regression-derived relation between the AVM velocity estimates and those obtained using acoustic Doppler current profilers (ADCPs). The uncertainty estimation method is based on the first-order variance method, but the AVM velocity error is estimated from an empirical perspective, using the statistics of the IVR regression. Some uncertainty exists regarding whether to include the standard error of the IVR regression (????2) in the discharge uncertainty. At the 5-minute time scale when ?? ??2 is included, it has the dominant contribution to the discharge uncertainty, and the discharge uncertainty (expressed as the standard deviation of the discharge estimate) is about 5 m3/s at one gage and 8 m3/s at the other, independent of discharge. When ????2 is not included, the discharge uncertainty at the 5-minute time scale is much smaller (about 0.5 m3/s) and depends more strongly on discharge. For time scales one day or greater and when ????2 is not included, the uncertainty of the IVR parameters dominates the discharge uncertainty. The value of the discharge uncertainty is about 0.4 m3/s for one gage and 0.5 m3/s for the other gage at long time scales.
NASA Astrophysics Data System (ADS)
Dumusque, X.; Boisse, I.; Santos, N. C.
2014-12-01
This paper presents SOAP 2.0, a new version of the Spot Oscillation And Planet (SOAP) code that estimates in a simple way the photometric and radial velocity (RV) variations induced by active regions. The inhibition of the convective blueshift (CB) inside active regions is considered, as well as the limb brightening effect of plages, a quadratic limb darkening law, and a realistic spot and plage contrast ratio. SOAP 2.0 shows that the activity-induced variation of plages is dominated by the inhibition of the CB effect. For spots, this effect becomes significant only for slow rotators. In addition, in the case of a major active region dominating the activity-induced signal, the ratio between the FWHM and the RV peak-to-peak amplitudes of the cross correlation function can be used to infer the type of active region responsible for the signal for stars with v sin i <=8 km s-1. A ratio smaller than three implies a spot, while a larger ratio implies a plage. Using the observation of HD 189733, we show that SOAP 2.0 manages to reproduce the activity variation as well as previous simulations when a spot is dominating the activity-induced variation. In addition, SOAP 2.0 also reproduces the activity variation induced by a plage on the slowly rotating star α Cen B, which is not possible using previous simulations. Following these results, SOAP 2.0 can be used to estimate the signal induced by spots and plages, but also to correct for it when a major active region is dominating the RV variation. . The work in this paper is based on observations made with the MOST satellite, the HARPS instrument on the ESO 3.6 m telescope at La Silla Observatory (Chile), and the SOPHIE instrument at the Observatoire de Haute Provence (France).
Dumusque, X.; Boisse, I.; Santos, N. C.
2014-12-01
This paper presents SOAP 2.0, a new version of the Spot Oscillation And Planet (SOAP) code that estimates in a simple way the photometric and radial velocity (RV) variations induced by active regions. The inhibition of the convective blueshift (CB) inside active regions is considered, as well as the limb brightening effect of plages, a quadratic limb darkening law, and a realistic spot and plage contrast ratio. SOAP 2.0 shows that the activity-induced variation of plages is dominated by the inhibition of the CB effect. For spots, this effect becomes significant only for slow rotators. In addition, in the case of a major active region dominating the activity-induced signal, the ratio between the FWHM and the RV peak-to-peak amplitudes of the cross correlation function can be used to infer the type of active region responsible for the signal for stars with v sin i ≤8 km s{sup –1}. A ratio smaller than three implies a spot, while a larger ratio implies a plage. Using the observation of HD 189733, we show that SOAP 2.0 manages to reproduce the activity variation as well as previous simulations when a spot is dominating the activity-induced variation. In addition, SOAP 2.0 also reproduces the activity variation induced by a plage on the slowly rotating star α Cen B, which is not possible using previous simulations. Following these results, SOAP 2.0 can be used to estimate the signal induced by spots and plages, but also to correct for it when a major active region is dominating the RV variation.
NASA Astrophysics Data System (ADS)
Karagoz, Ozlem; Chimoto, Kosuke; Citak, Seckin; Ozel, Oguz; Yamanaka, Hiroaki; Hatayama, Ken
2015-11-01
In this study, we aimed to explore the S-wave velocity structure of shallow soils using microtremors in order to estimate site responses in Tekirdag and surrounding areas (NW Turkey). We collected microtremor array data at 44 sites in Tekirdag, Marmara Ereglisi, Corlu, and Muratlı. The phase velocities of Rayleigh waves were estimated from the microtremor data using a Spatial Autocorrelation method. Then, we applied a hybrid genetic simulated annealing algorithm to obtain a 1D S-wave velocity structure at each site. Comparison between the horizontal-to-vertical ratio of microtremors and computed ellipticities of the fundamental mode Rayleigh waves showed good agreement with validation models. The depth of the engineering bedrock changed from 20 to 50 m in the Tekirdag city center and along the coastline with a velocity range of 700-930 m/s, and it ranged between 10 and 65 m in Marmara Ereglisi. The average S-wave velocity of the engineering bedrock was 780 m/s in the region. We obtained average S-wave velocities in the upper 30 m to compare site amplifications. Empirical relationships between the AVs30, the site amplifications, and also average topographic slopes were established for use in future site effects microzonation studies in the region.
NASA Astrophysics Data System (ADS)
Mutlu, Sunay; Tün, Muammer; Güney, Yücel; Ecevitoǧlu, Berkan
2014-05-01
Turkey, which is one of the world's most active earthquake zones located within the Alpine-Himalayan seismic belt. The major part of the territory of the country is at risk of earthquakes that causes damage and loss of life. The important indication of this danger is the past earthquakes resulted with losses. Turkey has experienced many destructive earthquakes in the last 15 years. In 1999 Gölcük Earthquake with the magnitude of 7.4, Düzce Earthquake with the magnitude of 7.2 and in 2011 Van Earthquake with the magnitude of 7.2-Van resulted with thousands of loss of life and damage to property as billions of thousand liras. It is quite important to doing microzonation works in these areas and estimation of behaviors during the earthquake in order to prevent occurring damages in settlements and areas will be settle. Soil amplification comes from the most basic parameter used in the microzonation works. This study was made in Eskisehir urban area which is one of the most urbanized and industrialized cities of Turkey in recent years. This study aim to amplification that may occur due to the earthquake to effects of Eskisehir region. It was used that seismic refraction data in 23 different location and 96 borehole data in settlement. Local soil properties variation upon amplification influence was investigated depending on SPT-N values and wave velocity data from seismic refraction. Average shear wave velocities for each type of surface to 30 m were found that each borehole point by equations İyisan (1996), and Jafari et al. (1997) using the resulting values. In addition, relative amplifications has been calculated by Midorikawa (1987) and Borcherdt et al's (1991) approaches. Then, these parameters have been mapped spatial changes using GIS (Geographical Information Systems) techniques. Porsuk river and its surroundings might have caused a high soil amplification result due to the low speed and soft soil when analyze the results of maps. In addition, it is thought
Thakur, S Chakraborty; McCarren, D; Lee, T; Fedorczak, N; Manz, P; Scime, E E; Tynan, G R; Xu, M; Yu, J
2012-10-01
We compare measurements of radially sheared azimuthal plasma flow based on time delay estimation (TDE) between two spatially separated Langmuir probes, Mach probes and laser induced fluorescence (LIF). TDE measurements cannot distinguish between ion fluid velocities and phase velocities. TDE and Mach probes are perturbative, so we compare the results against LIF, a non-perturbative, spatially resolved diagnostic technique that provides direct measurements of the ion velocity distribution functions. The bulk ion flow is determined from the Doppler shift of the Argon absorption line at 668.6139 nm. We compare results from all the three diagnostics, at various magnetic fields, which acts as a control knob for development of drift wave turbulence. We find that while Mach probes and LIF give similar profiles, TDE measurements typically overestimate the velocities and are also sensitive to the drift wave modes being investigated.
Field-scale estimation of gas permeability and subsequent computation of pore-gas velocity profiles are critical elements of sound soil venting design. It has been our experience however in U.S. EPA's technical assistance program, provided by the Office of Research and Developme...
NASA Astrophysics Data System (ADS)
Jung, W. Y.; Wood, W. T.
2014-12-01
We have estimated temperatures at the Moho surface by employing a published empirical relationship of Perry et al's work (JGR, doi:10.1029/2005JB003921) to the observed heat flow measurements in the East Sea (Sea of Japan), Korea. We assumed in our computation that the parameter values are all the same although the Perry et al's relationship between crustal thickness and heat flows to compute Moho temperature was derived for the Canadian Shield. For the heat flow data, we used the published global heat flow data (http://www.heatflow.und.edu) augmented with some recent heat flow measurements from Korea, and the LLN3_G3Dv3 for P-wave tomography model (JGR, doi:10.1029/2012JB009525). Preliminary results do not show a significant correlation between the computed Moho temperature and the P-wave velocity model perhaps due to uncertainty in the parameter values used in the computation as well as the empirical relation. An empirical relationship between the observed heat flow and the Moho temperature for the Canadian shield might be different for a backarec basin area like the East Sea, Korea. However, we noted that there exists a moderate negative correlation between the total crustal thickness and heat flow - less heat flows with increasing crustal thickness with a relation of Heat_Flow (mW/m2) = 205 - 18.3 * Crustal_Thickness (km). The modeled Moho temperature displays a trend of higher values (900o K -1400o K) from Japan toward the beneath of Yamato Basin and Rise in the NW direction, and beneath the Ulleung Basin area. Another higher Moho temperature (>1000o K) contour band is observed in the area north of Japan Basin, approximately centered along the 139.5o E.
NASA Astrophysics Data System (ADS)
Sollberger, S.; Perez, K.; Schubert, C. J.; Eugster, W.; Wehrli, B.; Del Sontro, T.
2013-12-01
Currently, carbon dioxide (CO2) and methane (CH4) emissions from lakes, reservoirs and rivers are readily investigated due to the global warming potential of those gases and the role these inland waters play in the carbon cycle. However, there is a lack of high spatiotemporally-resolved emission estimates, and how to accurately assess the gas transfer velocity (K) remains controversial. In anthropogenically-impacted systems where run-of-river reservoirs disrupt the flow of sediments by increasing the erosion and load accumulation patterns, the resulting production of carbonic greenhouse gases (GH-C) is likely to be enhanced. The GH-C flux is thus counteracting the terrestrial carbon sink in these environments that act as net carbon emitters. The aim of this project was to determine the GH-C emissions from a medium-sized river heavily impacted by several impoundments and channelization through a densely-populated region of Switzerland. Estimating gas emission from rivers is not trivial and recently several models have been put forth to do so; therefore a second goal of this project was to compare the river emission models available with direct measurements. Finally, we further validated the modeled fluxes by using a combined approach with water sampling, chamber measurements, and highly temporal GH-C monitoring using an equilibrator. We conducted monthly surveys along the 120 km of the lower Aare River where we sampled for dissolved CH4 (';manual' sampling) at a 5-km sampling resolution, and measured gas emissions directly with chambers over a 35 km section. We calculated fluxes (F) via the boundary layer equation (F=K×(Cw-Ceq)) that uses the water-air GH-C concentration (C) gradient (Cw-Ceq) and K, which is the most sensitive parameter. K was estimated using 11 different models found in the literature with varying dependencies on: river hydrology (n=7), wind (2), heat exchange (1), and river width (1). We found that chamber fluxes were always higher than boundary
Report: Affinity Chromatography.
ERIC Educational Resources Information Center
Walters, Rodney R.
1985-01-01
Supports, affinity ligands, immobilization, elution methods, and a number of applications are among the topics considered in this discussion of affinity chromatography. An outline of the basic principles of affinity chromatography is included. (JN)
NASA Astrophysics Data System (ADS)
Graymer, R. W.; Simpson, R. W.
2014-12-01
Graymer and Simpson (2013, AGU Fall Meeting) showed that in a simple 2D multi-fault system (vertical, parallel, strike-slip faults bounding blocks without strong material property contrasts) slip rate on block-bounding faults can be reasonably estimated by the difference between the mean velocity of adjacent blocks if the ratio of the effective locking depth to the distance between the faults is 1/3 or less ("effective" locking depth is a synthetic parameter taking into account actual locking depth, fault creep, and material properties of the fault zone). To check the validity of that observation for a more complex 3D fault system and a realistic distribution of observation stations, we developed a synthetic suite of GPS velocities from a dislocation model, with station location and fault parameters based on the San Francisco Bay region. Initial results show that if the effective locking depth is set at the base of the seismogenic zone (about 12-15 km), about 1/2 the interfault distance, the resulting synthetic velocity observations, when clustered, do a poor job of returning the input fault slip rates. However, if the apparent locking depth is set at 1/2 the distance to the base of the seismogenic zone, or about 1/4 the interfault distance, the synthetic velocity field does a good job of returning the input slip rates except where the fault is in a strong restraining orientation relative to block motion or where block velocity is not well defined (for example west of the northern San Andreas Fault where there are no observations to the west in the ocean). The question remains as to where in the real world a low effective locking depth could usefully model fault behavior. Further tests are planned to define the conditions where average cluster-defined block velocities can be used to reliably estimate slip rates on block-bounding faults. These rates are an important ingredient in earthquake hazard estimation, and another tool to provide them should be useful.
NASA Astrophysics Data System (ADS)
Iwase, Ryoichi
2016-07-01
An in situ method of estimating the seismic wave velocity at the seafloor surface by observing the particle motion of a wave transmitted into the sediment is presented; this method uses a sound source whose location is known. Conversely, a sound source localization method using the obtained seismic velocities and involving particle motion observation is also presented. Although this method is applicable only when the sound source exists within the critical incidence angle range, it is expected to contribute to the tracing of vocalizing baleen whales, which are unknown around Japanese waters.
Tasinkevych, Yuriy; Podhajecki, Jerzy; Falińska, Katarzyna; Litniewski, Jerzy
2016-02-01
The paper presents a method that allows the thickness of a compact bone layer and longitudinal wave velocity in the bone to be determined simultaneously with the use of reflected waves, with particular emphasis on the case of layers when the propagation time through the layer is shorter than the time duration of the interrogating pulse. The proposed method estimates simultaneously the thickness of the cortical bone layer and acoustic wave velocity by fitting the temporal spectrum of the simulated reflected wave to the spectrum of the reflected wave measured experimentally. For the purpose of echo-simulations the model of "soft tissue - compact bone layer - cancellous bone" was developed. Next, the cost function was defined as the least square error between the measured and simulated temporal spectra. Minimization of the cost function allowed us to determine the values of the parameters of the cortical bone layer which best fitted the measurements. To solve the optimization problem a simulated annealing algorithm was used. The method was tested using acoustic data obtained at the frequency of 0.6 MHz and 1 MHz respectively for a custom designed bone mimicking phantom and a calf femur. For the cortical shell of the calf femur whose thickness varies from 2.1 mm to 2.4 mm and velocity of 2910 m/s, the relative errors of the thickness estimation ranged from 0.4% to 5.5%. The corresponding error of the acoustic wave velocity estimation in the layer was 3.1%. In the case of artificial bone the thickness of the cortical layer was equal to 1.05 and 1.2 mm and acoustic wave velocity was 2900 m/s. These parameters were determined with the errors ranging from 1.9% to 10.8% and from 3.9% to 4.5% respectively.
Tasinkevych, Yuriy; Podhajecki, Jerzy; Falińska, Katarzyna; Litniewski, Jerzy
2016-02-01
The paper presents a method that allows the thickness of a compact bone layer and longitudinal wave velocity in the bone to be determined simultaneously with the use of reflected waves, with particular emphasis on the case of layers when the propagation time through the layer is shorter than the time duration of the interrogating pulse. The proposed method estimates simultaneously the thickness of the cortical bone layer and acoustic wave velocity by fitting the temporal spectrum of the simulated reflected wave to the spectrum of the reflected wave measured experimentally. For the purpose of echo-simulations the model of "soft tissue - compact bone layer - cancellous bone" was developed. Next, the cost function was defined as the least square error between the measured and simulated temporal spectra. Minimization of the cost function allowed us to determine the values of the parameters of the cortical bone layer which best fitted the measurements. To solve the optimization problem a simulated annealing algorithm was used. The method was tested using acoustic data obtained at the frequency of 0.6 MHz and 1 MHz respectively for a custom designed bone mimicking phantom and a calf femur. For the cortical shell of the calf femur whose thickness varies from 2.1 mm to 2.4 mm and velocity of 2910 m/s, the relative errors of the thickness estimation ranged from 0.4% to 5.5%. The corresponding error of the acoustic wave velocity estimation in the layer was 3.1%. In the case of artificial bone the thickness of the cortical layer was equal to 1.05 and 1.2 mm and acoustic wave velocity was 2900 m/s. These parameters were determined with the errors ranging from 1.9% to 10.8% and from 3.9% to 4.5% respectively. PMID:26522955
NASA Astrophysics Data System (ADS)
Sandoval-Soto, L.; Stanimirov, M.; von Hobe, M.; Schmitt, V.; Valdes, J.; Wild, A.; Kesselmeier, J.
2005-06-01
COS uptake by trees, as observed under dark/light changes and under application of the plant hormone abscisic acid, exhibited a strong correlation with the CO2 assimilation rate and the stomatal conductance. As the uptake of COS occurred exclusively through the stomata we compared experimentally derived and re-evaluated deposition velocities (Vd; related to stomatal conductance) for COS and CO2. We show that Vd of COS is generally significantly larger than that of CO2. We therefore introduced this attribute into a new global estimate of COS fluxes into vegetation. The new global estimate of the COS uptake based on available net primary productivity data (NPP) ranges between 0.69-1.40 Tga-1. However, as a COS molecule is irreversibly split in contrast to CO2 which is released again by respiration processes, we took into account the Gross Primary Productivity (GPP) representing the true CO2 leaf flux the COS uptake has to be related to. Such a GPP based deposition estimate ranged between 1.4--2.8 Tga-1 (0.73-1.50 TgSa-1). We believe that in order to obtain accurate global COS sink estimates such a GPP-based estimate corrected by the different deposition velocities of COS and CO2 must be taken into account.
NASA Astrophysics Data System (ADS)
Ogawa, Akira
2010-12-01
There are many types of cyclone dust collectors for separating the fine solid and dust particles from gases in the various industries and also in the home used purposes. For estimating the power loss and the collection efficiency, one of the most important factors is the maximum tangential velocity V θm in the vortex core region in the cyclone body. In order to determine V θm by the simple method, it is useful to apply the mechanical balance of the angular momentum fluxes under the assumption of Ogawa combined vortex model which is composed of the quasi-forced vortex in the vortex core region and also the quasi-free vortex surrounded the vortex core region and also under the assumption of the introduction of equivalent length Heq corresponding to the cone spaces of the cyclone body and the dust bunker. On the other hand, the mean rotational velocity V oi near the concave wall surface is also estimated by the mechanical balance of angular momentum fluxes with the moment of viscous friction force. For confirming the general applications of the obtained equations, the returned flow types cyclones changed the throat diameter D3 are designed. The material of the cyclone is the transparent acrylic resin. Therefore the inner surface of the cyclone body can be regarded as smooth surface. The comparisons of the measured velocities V θm and V oi by a cylindrical Pitot tube are shown in good agreement with those of the proposed equations. The above stated results are described in detail.
Melching, Charles S.; Oberg, Kevin A.
1993-01-01
The acoustic velocity meter (AVM) on the Chicago Sanitary and Ship Canal (the Canal) at Romeoville, Ill., provides vital information for the accounting of the diversion of water from Lake Michigan. A detailed analysis of the discharge record on the Canal at Romeoville was done by the U.S. Geological Survey to establish the most accurate estimates of discharge for water years 1986-91. The analysis involved (1) checking the consistency of the discharges estimated by two different AVM's installed at Romeoville for consecutive time periods by statistical and regression analyses, (2) adjusting the discharge record to account for corrections to the width and depth of the Canal determined by field measurements, and (3) development of equations for estimating discharge on days when the AVM was inoperative using discharge estimates made by the Metropolitan Water Reclamation District of Greater Chicago at the lock, powerhouse, and controlling works at Lockport, Ill. No signi- ficant difference in the discharge estimates made by the two AVM's could be documented. The estimation equations combined regression analysis with physical principles of the outlet-works operation. The estimation equations simulated the verification period of October 1, 1991, to May 31, 1992, within 0.22, 5.15, and 0.66 percent for the mean, standard deviation, and skewness coefficient, respectively. Discharges were recalculated for the corrected width and depth, estimated for the periods of AVM inoperation, and entered into the discharge record for the station.
NASA Astrophysics Data System (ADS)
Sandoval-Soto, L.; Stanimirov, M.; von Hobe, M.; Schmitt, V.; Valdes, J.; Wild, A.; Kesselmeier, J.
2005-01-01
COS uptake by trees, as observed under dark/light changes and under application of the plant hormone abscisic acid, exhibited a strong correlation with the CO2 assimilation rate and the stomatal conductance. As the uptake of COS occurred exclusively through the stomata we compared experimentally derived and re-evaluated deposition velocities (Vd for COS and CO2). We show that Vd of COS is generally significantly larger than that of CO2. We therefore introduced this attribute into a new global estimate of COS fluxes into vegetation. The global COS uptake by vegetation as estimated by the new model ranges between 0.69-1.40 Tg a-1, based on the Net Primary Productivity (NPP). Taking into account Gross Primary Productivity (GPP) the deposition estimate ranges between 1.37-2.81 Tg a-1 (0.73-1.50 Tg S a-1). We believe that in order to obtain accurate and reliable global NPP-based estimates for the COS flux into vegetation, the different deposition velocities of COS and CO2 must be taken into account.
Hole, Lars R; Brunner, Sibyl H; Hanssen, Jan Erik; Zhang, Leiming
2008-08-01
The conditional time averaged gradient method was used to measure air-surface exchange of nitrogen and sulphur compounds at a semi-alpine site in Southern Norway. Dry deposition velocities were then obtained from the bi-weekly concentration gradient measurements. Annual deposition velocities were found to be 1.4, 11.8 and 4.0 mm s(-1) for NH3, HNO3 and SO2, respectively, if all data were included, and to be 10.8, 11.8 and 13.0 mm s(-1), respectively, if only positive values were included. Measured deposition velocities were compared to two sets of values estimated from a big-leaf dry deposition module applying to two different land types (short grass and forbs, and tundra), driven by measured micrometeorological parameters. The deposition module gives reasonable values for this site throughout the year, but does not reproduce the large variability as shown in the measured data. No apparent seasonal variations were found from either measurements or module estimates due to the very low productivity of the studied area.
NASA Astrophysics Data System (ADS)
Ozakin, Yaman; Ben-Zion, Yehuda
2016-04-01
We estimate values of P wave velocity and P attenuation coefficients (QP) for the subsurface material at the Sage Brush Flat site along the Clark branch of the San Jacinto Fault Zone. The data are generated by 33 Betsy gunshots and recorded by a spatially dense array of 1108 vertical component geophones deployed in a rectangular grid that is approximately 600 m x 600 m. We automatically pick the arrival times of the seismic body waves from each explosion arriving at stations within 200 m. These measurements are used to derive an average velocity map with velocity values ranging from 500 m/s to 1250 m/s. We estimate the energy of the early P waves by squaring the amplitudes in a short window relative to the automatic picks. These energies are fitted to a decay function representing the geometrical spreading and intrinsic attenuation. By separating the stations into spatial bins and calculating attenuation values for each by linear regression, we construct a QP values map. Most of the QP values are in 5-20 range, which is consistent with other studies of shallow fault zone regions.
NASA Astrophysics Data System (ADS)
Flores-Estrella, H.; Aguirre, J.; Boore, D.; Yussim, S.
2001-12-01
Microtremor recordings have become a useful tool for microzonation studies in countries with low to moderate seismicity and also in countries where there are few seismographs or the recurrence time for an earthquake is quite long. Microtremor recordings can be made at almost any time and any place without needing to wait for an earthquake. The measurements can be made using one station or an array of stations. Microtremor recordings can be used to estimate site response directly (e.g. by using Nakamura's technique), or they can be used to estimate shear-wave velocities, from which site response can be calculated. A number of studies have found that the direct estimation of site response may be unreliable, except for identifying the fundamental resonant period of a site. Obtaining shear-wave velocities requires inverting measurements of Rayleigh wave phase velocities from microtremors, which are obtained by using the Spatial Autocorrelation (SPAC) (Aki, 1957) or the Frequency-Wave Number (F-K) (Horike, 1985) methods. Estimating shear-wave velocities from microtremor recordings is a cheaper alternative than direct methods, such as the logging of boreholes. In this work we use simultaneous microtremor recordings from triangular arrays located at two sites in Mexico City, Mexico, one ("Texcoco") with a lacustrine sediment layer of about 200 m depth, and the other one ("Ciudad Universitaria") underlain by 2,000 year old basaltic flows from Xitle volcano. The data are analyzed using both the SPAC method and by the standard F-K method. The results obtained from the SPAC method are more consistent with expectations from the geological conditions and an empirical transfer function (Montalvo et al., 2001) than those from F-K method. We also analyze data from the Hollister Municipal Airport in California. The triangular array at this site is located near a borehole from which seismic velocities have been obtained using a downhole logging method (Liu et al., 2000). We compare
Nishino, Hideo; Takemoto, Mikio; Chubachi, Noriyoshi
2004-08-09
A method for measuring the diameter/thickness (d/t) of a pipe using a characteristic of a hollow cylindrical guided wave (HCGW) is presented. The HCGW is an ultrasonic guided wave propagating along a pipe. In the first part of this letter, we briefly show that the primary wave (first-arriving wave packet from an impulse source) of the HCGW achieves a faster group velocity for a larger d/t. Experimental verifications were carried out for aluminum pipes (several different d/t's) using a laser ultrasonic method to generate the HCGW. The experimental results are in fairly good agreement with the theoretical prediction described.
NASA Technical Reports Server (NTRS)
Rottger, J.
1986-01-01
The determination of the turbulent energy dissipation rate or the eddy diffusion coefficient from radar observations can be done through the turbulence refractive index structure constant, deduced from calibrated echo power measurements, or through the turbulent velocity fluctuations, deduced from the echo spectrum width. Besides the radar parameters, power and spectrum width, the first approach needs knowledge of profiles of temperature and electron density in the mesosphere and the fraction of the radar volume filled with turbulence. The latter approach needs knowledge of the temperature profile, namely, the Brunt-Vaisala frequency. The use of this latter approach is demonstrated.
Foiret, Josquin; Minonzio, Jean-Gabriel; Chappard, Christine; Talmant, Maryline; Laugier, Pascal
2014-09-01
This paper reports for the first time on inverse estimation of several bone properties from guided-wave measurements in human bone samples. Previously, related approaches have focused on ultrasonic estimation of a single bone property at a time. The method is based on two steps: the multi-Lamb mode response is analyzed using the singular value decomposition signal processing method recently introduced in the field, then an identification procedure is run to find thickness and anisotropic elastic properties of the considered specimen. Prior to the measurements on bone, the method is validated on cortical bone-mimicking phantoms. The repeatability and the trueness of the estimated parameters on bone-mimicking phantoms were found around a few percent. Estimation of cortical thickness on bone samples was in good agreement with cortical thickness derived from high-resolution peripheral quantitative computed tomography data analysis of the samples.
Vu, Cung; Nihei, Kurt T; Schmitt, Denis P; Skelt, Christopher; Johnson, Paul A; Guyer, Robert; TenCate, James A; Le Bas, Pierre-Yves
2012-10-16
In some aspects of the disclosure, a method for creating three-dimensional images of non-linear properties and the compressional to shear velocity ratio in a region remote from a borehole using a conveyed logging tool is disclosed. In some aspects, the method includes arranging a first source in the borehole and generating a steered beam of elastic energy at a first frequency; arranging a second source in the borehole and generating a steerable beam of elastic energy at a second frequency, such that the steerable beam at the first frequency and the steerable beam at the second frequency intercept at a location away from the borehole; receiving at the borehole by a sensor a third elastic wave, created by a three wave mixing process, with a frequency equal to a difference between the first and second frequencies and a direction of propagation towards the borehole; determining a location of a three wave mixing region based on the arrangement of the first and second sources and on properties of the third wave signal; and creating three-dimensional images of the non-linear properties using data recorded by repeating the generating, receiving and determining at a plurality of azimuths, inclinations and longitudinal locations within the borehole. The method is additionally used to generate three dimensional images of the ratio of compressional to shear acoustic velocity of the same volume surrounding the borehole.
NASA Astrophysics Data System (ADS)
Palmsten, Margaret L.; Todd Holland, K.; Plant, Nathaniel G.
2013-09-01
Numerous numerical modeling studies have been completed in support of an extensive recovery program for the endangered white sturgeon (Acipenser transmontanus) on the Kootenai River near Bonner's Ferry, ID. A technical hurdle in the interpretation of these model results is the transfer of information from the specialist to nonspecialist such that practical decisions utilizing the numerical simulations can be made. To address this, we designed and trained a Bayesian network to provide probabilistic prediction of depth-averaged velocity. Prediction of this critical parameter governing suitable spawning habitat was obtained by exploiting the dynamic relationships between variables derived from model simulations with associated parameter uncertainties. Postdesign assessment indicates that the most influential environmental variables in order of importance are river discharge, depth, and width, and water surface slope. We demonstrate that the probabilistic network not only reproduces the training data with accuracy similar to the accuracy of a numerical model (root-mean-squared error of 0.10 m/s), but that it makes reliable predictions on the same river at times and locations other than where the network was trained (root mean squared error of 0.09 m/s). Additionally, the network showed similar skill (root mean square error of 0.04 m/s) when predicting velocity on the Apalachicola River, FL, a river of similar shape and size to the Kootenai River where a related sturgeon population is also threatened.
NASA Astrophysics Data System (ADS)
Morales, L. E. A. P.; Aguirre, J.; Vazquez Rosas, R.; Suarez, G.; Contreras Ruiz-Esparza, M. G.; Farraz, I.
2014-12-01
Methods that use seismic noise or microtremors have become very useful tools worldwide due to its low costs, the relative simplicity in collecting data, the fact that these are non-invasive methods hence there is no need to alter or even perforate the study site, and also these methods require a relatively simple analysis procedure. Nevertheless the geological structures estimated by this methods are assumed to be parallel, isotropic and homogeneous layers. Consequently precision of the estimated structure is lower than that from conventional seismic methods. In the light of these facts this study aimed towards searching a new way to interpret the results obtained from seismic noise methods. In this study, seven triangular SPAC (Aki, 1957) arrays were performed in the city of Coatzacoalcos, Veracruz, varying in sizes from 10 to 100 meters. From the autocorrelation between the stations of each array, a Rayleigh wave phase velocity dispersion curve was calculated. Such dispersion curve was used to obtain a S wave parallel layers velocity (VS) structure for the study site. Subsequently the horizontal to vertical ratio of the spectrum of microtremors H/V (Nogoshi and Igarashi, 1971; Nakamura, 1989, 2000) was calculated for each vertex of the SPAC triangular arrays, and from the H/V spectrum the fundamental frequency was estimated for each vertex. By using the H/V spectral ratio curves interpreted as a proxy to the Rayleigh wave ellipticity curve, a series of VS structures were inverted for each vertex of the SPAC array. Lastly each VS structure was employed to calculate a 3D velocity model, in which the exploration depth was approximately 100 meters, and had a velocity range in between 206 (m/s) to 920 (m/s). The 3D model revealed a thinning of the low velocity layers. This proved to be in good agreement with the variation of the fundamental frequencies observed at each vertex. With the previous kind of analysis a preliminary model can be obtained as a first
NASA Astrophysics Data System (ADS)
Klomp, Matthijs; Gao, Yunlong; Bruzelius, Fredrik
2014-05-01
Vehicle speed is one of the important quantities in vehicle dynamics control. Estimation of the slope angle is in turn a necessity for correct dead reckoning from vehicle acceleration. In the present work, estimation of vehicle speed is applied to a hybrid vehicle with an electric motor on the rear axle and a combustion engine on the front axle. The wheel torque information, provided by electric motor, is used to early detect excessive wheel slip and improve the accuracy of the estimate. A best-wheel selection approach is applied as the observation variable of a Kalman filter which reduces the influence of slipping wheels as well as reducing the computational effort. The performance of the proposed algorithm is illustrated on a test data recorded at a winter test ground with excellent results, even for extreme conditions such as when all four wheels are spinning.
John H. Bradford; Stephen Holbrook; Scott B. Smithson
2004-12-09
The focus of this project is direct detection of DNAPL's specifically chlorinated solvents, via material property estimation from multi-fold surface ground-penetrating radar (GPR) data. We combine state-of-the-art GPR processing methodology with quantitative attribute analysis and material property estimation to determine the location and extent of residual and/or pooled DNAPL in both the vadose and saturated zones. An important byproduct of our research is state-of-the-art imaging which allows us to pinpoint attribute anomalies, characterize stratigraphy, identify fracture zones, and locate buried objects.
NASA Astrophysics Data System (ADS)
Tanimoto, T.; Okamoto, T.
2013-12-01
Modeling high-frequency (>1 Hz) seismic waves is known to be difficult but it is extremely important for earthquake hazard mitigation as many buildings have resonant frequencies above 1 Hz. In this study, we examine high-frequency waves at 1.64 Hz, generated by building-shaking experiments in California. The specific data we will examine are seismic data generated by shaking experiments of the Millikan Library between 2000 and 2002, located on the campus of California Institute of Technology in Pasadena, California. The excited wavefields were recorded by the broadband seismic network in the region (~150 stations), Southern California Seismic Network (SCSN). There were about 60 stations with good signal-to-noise ratios among SCSN stations. The maximum distance for signal detection was 323 km (station GRA). Based on numerical calculations for a regional seismic structure model (SCEC Community Velocity Model 11.9), we can show that the signals are dominated by surface waves (at 1.11 Hz and 1.64 Hz), whose energy is confined to shallow depths. The focus of this report will be on the cross-correlated signals between a station in the building (station MIK) and other stations. This cross-correlation may be viewed as a source deconvolution process and will let us focus on propagation in the medium. This cross-correlated phase can be expressed as a line integral of wavenumber along a propagation path for a direct (ballistic) phase, although it may contain complexity from the caustics (the Maslov index). Somewhat to our surprise, despite the fact that we are dealing with high frequency waves (1.64 Hz), we observe well-defined constant phase in many cross-correlated seismograms. If we knew the number of cycles between the source (Millikan) and a station, we could estimate phase velocity in principle but this is not possible and seems extremely hard because the number of cycles is about 50-100 or more. However, our signals do show frequency-dependence within a narrow (signal
Bohrer, Gil; Brandes, David; Mandel, James T; Bildstein, Keith L; Miller, Tricia A; Lanzone, Michael; Katzner, Todd; Maisonneuve, Charles; Tremblay, Junior A
2012-02-01
Soaring birds migrate in massive numbers worldwide. These migrations are complex and dynamic phenomena, strongly influenced by meteorological conditions that produce thermal and orographic uplift as the birds traverse the landscape. Herein we report on how methods were developed to estimate the strength of thermal and orographic uplift using publicly available digital weather and topography datasets at continental scale. We apply these methods to contrast flight strategies of two morphologically similar but behaviourally different species: golden eagle, Aquila chrysaetos, and turkey vulture, Cathartes aura, during autumn migration across eastern North America tracked using GPS tags. We show that turkey vultures nearly exclusively used thermal lift, whereas golden eagles primarily use orographic lift during migration. It has not been shown previously that migration tracks are affected by species-specific specialisation to a particular uplift mode. The methods introduced herein to estimate uplift components and test for differences in weather use can be applied to study movement of any soaring species.
Bohrer, Gil; Brandes, David; Mandel, James T; Bildstein, Keith L; Miller, Tricia A; Lanzone, Michael; Katzner, Todd; Maisonneuve, Charles; Tremblay, Junior A
2012-02-01
Soaring birds migrate in massive numbers worldwide. These migrations are complex and dynamic phenomena, strongly influenced by meteorological conditions that produce thermal and orographic uplift as the birds traverse the landscape. Herein we report on how methods were developed to estimate the strength of thermal and orographic uplift using publicly available digital weather and topography datasets at continental scale. We apply these methods to contrast flight strategies of two morphologically similar but behaviourally different species: golden eagle, Aquila chrysaetos, and turkey vulture, Cathartes aura, during autumn migration across eastern North America tracked using GPS tags. We show that turkey vultures nearly exclusively used thermal lift, whereas golden eagles primarily use orographic lift during migration. It has not been shown previously that migration tracks are affected by species-specific specialisation to a particular uplift mode. The methods introduced herein to estimate uplift components and test for differences in weather use can be applied to study movement of any soaring species. PMID:22077120
Low-complexity piecewise-affine virtual sensors: theory and design
NASA Astrophysics Data System (ADS)
Rubagotti, Matteo; Poggi, Tomaso; Oliveri, Alberto; Pascucci, Carlo Alberto; Bemporad, Alberto; Storace, Marco
2014-03-01
This paper is focused on the theoretical development and the hardware implementation of low-complexity piecewise-affine direct virtual sensors for the estimation of unmeasured variables of interest of nonlinear systems. The direct virtual sensor is designed directly from measured inputs and outputs of the system and does not require a dynamical model. The proposed approach allows one to design estimators which mitigate the effect of the so-called 'curse of dimensionality' of simplicial piecewise-affine functions, and can be therefore applied to relatively high-order systems, enjoying convergence and optimality properties. An automatic toolchain is also presented to generate the VHDL code describing the digital circuit implementing the virtual sensor, starting from the set of measured input and output data. The proposed methodology is applied to generate an FPGA implementation of the virtual sensor for the estimation of vehicle lateral velocity, using a hardware-in-the-loop setting.
Mori, J.
1991-01-01
Event record sections, which are constructed by plotting seismograms from many closely spaced earthquakes recorded on a few stations, show multiple free-surface reflections (PP, PPP, PPPP) of the P wave in the Imperial Valley. The relative timing of these arrivals is used to estimate the strength of the P-wave velocity gradient within the upper 5 km of the sediment layer. Consistent with previous studies, a velocity model with a value of 1.8 km/sec at the surface increasing linearly to 5.8 km/sec at a depth of 5.5 km fits the data well. The relative amplitudes of the P and PP arrivals are used to estimate the source depth for the aftershock distributions of the Elmore Ranch and Superstition Hills main shocks. Although the depth determination has large uncertainties, both the Elmore Ranch and Superstition Hills aftershock sequencs appear to have similar depth distribution in the range of 4 to 10 km. -Author
Hayashi, Shiho; Obara, Shinju; Murakawa, Masahiro; Hazama, Akihiro; Kusanagi, Masahiko; Katsuda, Shin-ichiro
2011-05-01
Pulse wave velocity (PWV), an index of arterial stiffness, is dependent not only on structural alterations in arterial wall but also on distending pressure, which could be related to wall distensibility. We investigated the efficacy of aortic PWV (AoPWV) for detecting early to moderate atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits. Pressure waves were recorded at the ascending, and proximal and distal abdominal aortas in 13 male normal and KHC rabbits aged 12 months under pentobarbital anesthesia when angiotensin II or sodium nitroprusside was infused intravenously. AoPWV was compared between the two rabbit groups at different mean arterial pressure (MAP) levels. Vascular diameter (D(m)) was measured using an intravascular ultrasound imaging system in the proximal thoracic and proximal abdominal aortas to determine pressure-strain elastic modulus (E(p)). AoPWV was correlated to MAP in the two rabbit groups (P < 0.001). AoPWV was slightly but significantly greater (< 0.5 m s(-1)) in the KHC rabbit group than in the normal rabbit group at MAP level >80 mm Hg (P < 0.01). The value of h/D(m) (h, wall thickness) was significantly high in the KHC rabbit group at any MAP level (P < 0.001) in these aortic regions. There was no significant difference in E(p) and D(m) between the two rabbit groups at any MAP level. AoPWV showed only a slight but significant increase in the young KHC rabbits at different MAP levels, which was mainly due to the increased h/D(m). AoPWV could underestimate aortic stiffness due to early to moderate atherosclerosis if AoPWV was adjusted for arterial pressure level.
NASA Astrophysics Data System (ADS)
Al-Shammari, Eiman Tamah; Petković, Dalibor; Danesh, Amir Seyed; Shamshirband, Shahaboddin; Issa, Mirna; Zentner, Lena
2016-05-01
Robotic operations need to be safe for unpredictable contacts. Joints with passive compliance with springs can be used for soft robotic contacts. However the joints cannot measure external collision forces. In this investigation was developed one passive compliant joint which have soft contacts with external objects and measurement capabilities. To ensure it, conductive silicone rubber was used as material for modeling of the compliant segments of the robotic joint. These compliant segments represent embedded sensors. The conductive silicone rubber is electrically conductive by deformations. The main task was to obtain elastic absorbers for the external collision forces. These absorbers can be used for measurement in the same time. In other words, the joint has an internal measurement system. Adaptive neuro fuzzy inference system (ANFIS) was used to estimate the safety level of the robotic joint by head injury criteria (HIC).
NASA Astrophysics Data System (ADS)
Vieira, V. M. N. C. S.; Sahlée, E.; Jurus, P.; Clementi, E.; Pettersson, H.; Mateus, M.
2015-09-01
Earth-System and regional models, forecasting climate change and its impacts, simulate atmosphere-ocean gas exchanges using classical yet too simple generalizations relying on wind speed as the sole mediator while neglecting factors as sea-surface agitation, atmospheric stability, current drag with the bottom, rain and surfactants. These were proved fundamental for accurate estimates, particularly in the coastal ocean, where a significant part of the atmosphere-ocean greenhouse gas exchanges occurs. We include several of these factors in a customizable algorithm proposed for the basis of novel couplers of the atmospheric and oceanographic model components. We tested performances with measured and simulated data from the European coastal ocean, having found our algorithm to forecast greenhouse gas exchanges largely different from the forecasted by the generalization currently in use. Our algorithm allows calculus vectorization and parallel processing, improving computational speed roughly 12× in a single cpu core, an essential feature for Earth-System models applications.
Fisher, Jason C.; Rousseau, Joseph P.; Bartholomay, Roy C.; Rattray, Gordon W.
2012-01-01
The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Energy, evaluated a three-dimensional model of groundwater flow in the fractured basalts and interbedded sediments of the eastern Snake River Plain aquifer at and near the Idaho National Laboratory to determine if model-derived estimates of groundwater movement are consistent with (1) results from previous studies on water chemistry type, (2) the geochemical mixing at an example well, and (3) independently derived estimates of the average linear groundwater velocity. Simulated steady-state flow fields were analyzed using backward particle-tracking simulations that were based on a modified version of the particle tracking program MODPATH. Model results were compared to the 5-microgram-per-liter lithium contour interpreted to represent the transition from a water type that is primarily composed of tributary valley underflow and streamflow-infiltration recharge to a water type primarily composed of regional aquifer water. This comparison indicates several shortcomings in the way the model represents flow in the aquifer. The eastward movement of tributary valley underflow and streamflow-infiltration recharge is overestimated in the north-central part of the model area and underestimated in the central part of the model area. Model inconsistencies can be attributed to large contrasts in hydraulic conductivity between hydrogeologic zones. Sources of water at well NPR-W01 were identified using backward particle tracking, and they were compared to the relative percentages of source water chemistry determined using geochemical mass balance and mixing models. The particle tracking results compare reasonably well with the chemistry results for groundwater derived from surface-water sources (-28 percent error), but overpredict the proportion of groundwater derived from regional aquifer water (108 percent error) and underpredict the proportion of groundwater derived from tributary valley underflow
NASA Astrophysics Data System (ADS)
Despax, Aurélien; Perret, Christian; Garçon, Rémy; Hauet, Alexandre; Belleville, Arnaud; Le Coz, Jérôme; Favre, Anne-Catherine
2016-02-01
Streamflow time series provide baseline data for many hydrological investigations. Errors in the data mainly occur through uncertainty in gauging (measurement uncertainty) and uncertainty in the determination of the stage-discharge relationship based on gaugings (rating curve uncertainty). As the velocity-area method is the measurement technique typically used for gaugings, it is fundamental to estimate its level of uncertainty. Different methods are available in the literature (ISO 748, Q + , IVE), all with their own limitations and drawbacks. Among the terms forming the combined relative uncertainty in measured discharge, the uncertainty component relating to the limited number of verticals often includes a large part of the relative uncertainty. It should therefore be estimated carefully. In ISO 748 standard, proposed values of this uncertainty component only depend on the number of verticals without considering their distribution with respect to the depth and velocity cross-sectional profiles. The Q + method is sensitive to a user-defined parameter while it is questionable whether the IVE method is applicable to stream-gaugings performed with a limited number of verticals. To address the limitations of existing methods, this paper presents a new methodology, called FLow Analog UnceRtainty Estimation (FLAURE), to estimate the uncertainty component relating to the limited number of verticals. High-resolution reference gaugings (with 31 and more verticals) are used to assess the uncertainty component through a statistical analysis. Instead of subsampling purely randomly the verticals of these reference stream-gaugings, a subsampling method is developed in a way that mimicks the behavior of a hydrometric technician. A sampling quality index (SQI) is suggested and appears to be a more explanatory variable than the number of verticals. This index takes into account the spacing between verticals and the variation of unit flow between two verticals. To compute the
NASA Astrophysics Data System (ADS)
Cartwright, Grace M.; Friedrichs, Carl T.; Smith, S. Jarrell
2013-12-01
Under conditions common in muddy coastal and estuarine environments, acoustic Doppler velocimeters (ADVs) can serve to estimate sediment settling velocity ( w s) by assuming a balance between upward turbulent Reynolds flux and downward gravitational settling. Advantages of this method include simple instrument deployment, lack of flow disturbance, and relative insensitivity to biofouling and water column stratification. Although this method is being used with increasing frequency in coastal and estuarine environments, to date it has received little direct ground truthing. This study compared in situ estimates of w s inferred by a 5-MHz ADV to independent in situ observations from a high-definition video settling column over the course of a flood tide in the bottom boundary layer of the York River estuary, Virginia, USA. The ADV-based measurements were found to agree with those of the settling column when the current speed at about 40 cm above the bed was greater than about 20 cm/s. This corresponded to periods when the estimated magnitude of the settling term in the suspended sediment continuity equation was four or more times larger than the time rate of change of concentration. For ADV observations restricted to these conditions, ADV-based estimates of w s (mean 0.48±0.04 mm/s) were highly consistent with those observed by the settling column (mean 0.45±0.02 mm/s). However, the ADV-based method for estimating w s was sensitive to the prescribed concentration of the non-settling washload, C wash. In an objective operational definition, C wash can be set equal to the lowest suspended solids concentration observed around slack water.
Affine projective Osserman structures
NASA Astrophysics Data System (ADS)
Gilkey, P.; Nikčević, S.
2013-08-01
By considering the projectivized spectrum of the Jacobi operator, we introduce the concept of projective Osserman manifold in both the affine and in the pseudo-Riemannian settings. If M is an affine projective Osserman manifold, then the deformed Riemannian extension metric on the cotangent bundle is both spacelike and timelike projective Osserman. Since any rank-1-symmetric space is affine projective Osserman, this provides additional information concerning the cotangent bundle of a rank-1 Riemannian symmetric space with the deformed Riemannian extension metric. We construct other examples of affine projective Osserman manifolds where the Ricci tensor is not symmetric and thus the connection in question is not the Levi-Civita connection of any metric. If the dimension is odd, we use methods of algebraic topology to show the Jacobi operator of an affine projective Osserman manifold has only one non-zero eigenvalue and that eigenvalue is real.
NASA Astrophysics Data System (ADS)
Sandoval-Soto, L.; Stanimirov, M.; Valdez, J.; von Hobe, M.; Schmitt, V.; Wild, A.; Kesselmeier, J.
2003-12-01
Carbonyl sulfide (COS, OCS) is a highly stable reduced sulfur gas species in the atmosphere. Due to its inertness within the troposphere it can be transported into the stratosphere where it contributes to form SO2 and sulfate aerosol. Additionally it may be involved in heterogeneous reactions in stratospheric ozone chemistry. One of the major sinks for this trace gas is the vegetation. Based on investigations with trees under a light and dark regime and reacting to the hormone abscisic acid we demonstrated the stomatal uptake of COS to be the dominating pathway for COS deposition to plant surfaces. Taking into account deposition velocities of COS, which are higher than for CO2, we recalculated the global COS deposition to vegetation based on a new refined estimation model.
Lee, M.W.
1999-01-01
The amount of in situ gas hydrate concentrated in the sediment pore space at the JAPEX/JNOC/GSC Mallik 2L-38 gas hydrate research well was estimated by using compressional-wave (P-wave) and shear-wave (S-wave) downhole log measurements. A weighted equation developed for relating the amount of gas hydrate concentrated in the pore space of unconsolidated sediments to the increase of seismic velocities was applied to the acoustic logs with porosities derived from the formation density log. A weight of 1.56 (W=1.56) and the exponent of 1 (n=1) provided consistent estimates of gas hydrate concentration from the S-wave and the P-wave logs. Gas hydrate concentration is as much as 80% in the pore spaces, and the average gas hydrate concentration within the gas-hydrate-bearing section from 897 m to 1110 m (excluding zones where there is no gas hydrate) was calculated at 39.0% when using P-wave data and 37.8% when using S-wave data.
Special Report: Affinity Chromatography.
ERIC Educational Resources Information Center
Parikh, Indu; Cuatrecasas, Pedro
1985-01-01
Describes the nature of affinity chromatography and its use in purifying enzymes, studying cell interactions, exploring hormone receptors, and other areas. The potential the technique may have in treating disease is also considered. (JN)
NASA Astrophysics Data System (ADS)
Bian, Changwei; Mao, Xinyan; Jiang, Wensheng; Gu, Yanzhen
2015-02-01
Sediment settling velocity ( w s) patterns are well established at the Huanghe and Changjiang river mouths, but no w s results have been reported for the Yellow Sea and the East China Sea (YSECS) shelves due to the labor-intensive and time-consuming aspect of traditional w s measurement approaches (e.g., settling column method). This disadvantage can be overcome by the acoustic Doppler velocimeter (ADV). In this study, ten ADV-based field campaigns were conducted over various seasons of the years 2011 and 2013 at six YSECS sites, five on the East China Sea shelf (28 to 87 m depth) and one on the Yellow Sea shelf (74 m depth). The results demonstrate that ADV backscatter was a reliable proxy of suspended sediment concentration over a measurement range of 1 to 1,000 mg/L. The ADV-estimated w s was highest (1.43-1.88 mm/s) in summer in the southern East China Sea, and lowest (0.07 mm/s) in spring in the northern Yellow Sea. This can plausibly be explained by the hydrodynamic environment and bottom sediment type at the campaign sites. More importantly, the data reveal evidence of marked seasonal variations of w s in the middle sector of the East China Sea, as well as intra-tidal variations at all campaign sites. However, these variations of w s are not directly regulated by current velocity or suspended sediment concentration. This aspect represents a major challenge in future research in this shelf region and, for that matter, in similar settings worldwide. Evidently, expanding on the well-resolved continuous time series provided by the ADV approach is a key step in this direction.
Li, Fubing; He, Qiong; Huang, Chengwu; Liu, Ke; Shao, Jinhua; Luo, Jianwen
2016-04-01
Pulse wave imaging (PWI) is an ultrasound-based method to visualize the propagation of pulse wave and to quantitatively estimate regional pulse wave velocity (PWV) of the arteries within the imaging field of view (FOV). To guarantee the reliability of PWV measurement, high frame rate imaging is required, which can be achieved by reducing the line density of ultrasound imaging or transmitting plane wave at the expense of spatial resolution and/or signal-to-noise ratio (SNR). In this study, a composite, full-view imaging method using motion matching was proposed with both high temporal and spatial resolution. Ultrasound radiofrequency (RF) data of 4 sub-sectors, each with 34 beams, including a common beam, were acquired successively to achieve a frame rate of ∼507 Hz at an imaging depth of 35 mm. The acceleration profiles of the vessel wall estimated from the common beam were used to reconstruct the full-view (38-mm width, 128-beam) image sequence. The feasibility of mapping local PWV variation along the artery using PWI technique was preliminarily validated on both homogeneous and inhomogeneous polyvinyl alcohol (PVA) cryogel vessel phantoms. Regional PWVs for the three homogeneous phantoms measured by the proposed method were in accordance with the sparse imaging method (38-mm width, 32-beam) and plane wave imaging method. Local PWV was estimated using the above-mentioned three methods on 3 inhomogeneous phantoms, and good agreement was obtained in both the softer (1.91±0.24 m/s, 1.97±0.27 m/s and 1.78±0.28 m/s) and the stiffer region (4.17±0.46 m/s, 3.99±0.53 m/s and 4.27±0.49 m/s) of the phantoms. In addition to the improved spatial resolution, higher precision of local PWV estimation in low SNR circumstances was also obtained by the proposed method as compared with the sparse imaging method. The proposed method might be helpful in disease detections through mapping the local PWV of the vascular wall. PMID:26773791
Li, Fubing; He, Qiong; Huang, Chengwu; Liu, Ke; Shao, Jinhua; Luo, Jianwen
2016-04-01
Pulse wave imaging (PWI) is an ultrasound-based method to visualize the propagation of pulse wave and to quantitatively estimate regional pulse wave velocity (PWV) of the arteries within the imaging field of view (FOV). To guarantee the reliability of PWV measurement, high frame rate imaging is required, which can be achieved by reducing the line density of ultrasound imaging or transmitting plane wave at the expense of spatial resolution and/or signal-to-noise ratio (SNR). In this study, a composite, full-view imaging method using motion matching was proposed with both high temporal and spatial resolution. Ultrasound radiofrequency (RF) data of 4 sub-sectors, each with 34 beams, including a common beam, were acquired successively to achieve a frame rate of ∼507 Hz at an imaging depth of 35 mm. The acceleration profiles of the vessel wall estimated from the common beam were used to reconstruct the full-view (38-mm width, 128-beam) image sequence. The feasibility of mapping local PWV variation along the artery using PWI technique was preliminarily validated on both homogeneous and inhomogeneous polyvinyl alcohol (PVA) cryogel vessel phantoms. Regional PWVs for the three homogeneous phantoms measured by the proposed method were in accordance with the sparse imaging method (38-mm width, 32-beam) and plane wave imaging method. Local PWV was estimated using the above-mentioned three methods on 3 inhomogeneous phantoms, and good agreement was obtained in both the softer (1.91±0.24 m/s, 1.97±0.27 m/s and 1.78±0.28 m/s) and the stiffer region (4.17±0.46 m/s, 3.99±0.53 m/s and 4.27±0.49 m/s) of the phantoms. In addition to the improved spatial resolution, higher precision of local PWV estimation in low SNR circumstances was also obtained by the proposed method as compared with the sparse imaging method. The proposed method might be helpful in disease detections through mapping the local PWV of the vascular wall.
Chowienczyk, Phil; Alastruey, Jordi
2015-01-01
While central (carotid-femoral) foot-to-foot pulse wave velocity (PWV) is considered to be the gold standard for the estimation of aortic arterial stiffness, peripheral foot-to-foot PWV (brachial-ankle, femoral-ankle, and carotid-radial) are being studied as substitutes of this central measurement. We present a novel methodology to assess theoretically these computed indexes and the hemodynamics mechanisms relating them. We created a database of 3,325 virtual healthy adult subjects using a validated one-dimensional model of the arterial hemodynamics, with cardiac and arterial parameters varied within physiological healthy ranges. For each virtual subject, foot-to-foot PWV was computed from numerical pressure waveforms at the same locations where clinical measurements are commonly taken. Our numerical results confirm clinical observations: 1) carotid-femoral PWV is a good indicator of aortic stiffness and correlates well with aortic PWV; 2) brachial-ankle PWV overestimates aortic PWV and is related to the stiffness and geometry of both elastic and muscular arteries; and 3) muscular PWV (carotid-radial, femoral-ankle) does not capture the stiffening of the aorta and should therefore not be used as a surrogate for aortic stiffness. In addition, our analysis highlights that the foot-to-foot PWV algorithm is sensitive to the presence of reflected waves in late diastole, which introduce errors in the PWV estimates. In this study, we have created a database of virtual healthy subjects, which can be used to assess theoretically the efficiency of physiological indexes based on pulse wave analysis. PMID:26055792
NASA Astrophysics Data System (ADS)
Peterson, C. D.; Jaffe, B.; Peters, R.
2004-12-01
intercept=0) yielding a linear relation y=0.71x with Rsq2=0.9 for this small data set. Using the inundation versus recurrence relation the following estimates are found: 500yr recurrence=300-400m inundation, 1000yr recurrence=700-800m inundation. At this locality 3 out of 5 tsunami (2,4,5) are directly correlated to central Cascadia coseismic-subsidence events, so are classified as near-field sources. Only one certain far-field tsunami (Alaska 1964) is recorded at this locality for the 1300yr period. It has been 300 years since the last Cascadia-generated tsunami (1700AD) and the probability for an associated high-velocity tsunami inundation of greater than 250m at Cannon Beach, estimated from a mean recurrence interval of 325yr, is 50 percent in the next fifty years.
NASA Astrophysics Data System (ADS)
Oda, Hitoshi
2016-06-01
The aspherical structure of the Earth is described in terms of lateral heterogeneity and anisotropy of the P- and S-wave velocities, density heterogeneity, ellipticity and rotation of the Earth and undulation of the discontinuity interfaces of the seismic wave velocities. Its structure significantly influences the normal mode spectra of the Earth's free oscillation in the form of cross-coupling between toroidal and spheroidal multiplets and self-coupling between the singlets forming them. Thus, the aspherical structure must be conversely estimated from the free oscillation spectra influenced by the cross-coupling and self-coupling. In the present study, we improve a spectral fitting inversion algorithm which was developed in a previous study to retrieve the global structures of the isotropic and anisotropic velocities of the P and S waves from the free oscillation spectra. The main improvement is that the geographical distribution of the intensity of the S-wave azimuthal anisotropy is represented by a nonlinear combination of structure coefficients for the anisotropic velocity structure, whereas in the previous study it was expanded into a generalized spherical harmonic series. Consequently, the improved inversion algorithm reduces the number of unknown parameters that must be determined compared to the previous inversion algorithm and employs a one-step inversion method by which the structure coefficients for the isotropic and anisotropic velocities are directly estimated from the fee oscillation spectra. The applicability of the improved inversion is examined by several numerical experiments using synthetic spectral data, which are produced by supposing a variety of isotropic and anisotropic velocity structures, earthquake source parameters and station-event pairs. Furthermore, the robustness of the inversion algorithm is investigated with respect to the back-ground noise contaminating the spectral data as well as truncating the series expansions by finite terms
Fan Affinity Laws from a Collision Model
ERIC Educational Resources Information Center
Bhattacharjee, Shayak
2012-01-01
The performance of a fan is usually estimated using hydrodynamical considerations. The calculations are long and involved and the results are expressed in terms of three affinity laws. In this paper we use kinetic theory to attack this problem. A hard sphere collision model is used, and subsequently a correction to account for the flow behaviour…
NASA Astrophysics Data System (ADS)
Kinzel, P. J.; Bauer, M.; Feller, M.; Holmquist-Johnson, C.; Preston, T.
2013-12-01
The use of unmanned aircraft systems (UAS) for environmental monitoring in the United States is anticipated to increase in the coming years as the Federal Aviation Administration (FAA) further develops guidelines to permit their integration into the National Airspace System. The U.S. Geological Survey's (USGS) National Unmanned Aircraft Systems Project Office routinely obtains Certificates of Authorization from the FAA for utilizing UAS technology for a variety of natural resource applications for the U.S. Department of the Interior (DOI). We evaluated the use of a small UAS along two reaches of the Platte River near Overton Nebraska, USA, to determine the accuracy of the system for mapping the extent and elevation of emergent sandbars and to test the ability of a hovering UAS to identify and track tracers to estimate water-surface velocity. The UAS used in our study is the Honeywell Tarantula Hawk RQ16 (T-Hawk), developed for the U.S. Army as a reconnaissance and surveillance platform. The T-Hawk has been recently modified by USGS, and certified for airworthiness by the DOI - Office of Aviation Services, to accommodate a higher-resolution imaging payload than was originally deployed with the system. The T-Hawk is currently outfitted with a Canon PowerShot SX230 HS with a 12.1 megapixel resolution and intervalometer to record images at a user defined time step. To increase the accuracy of photogrammetric products, orthoimagery and DEMs using structure-from-motion (SFM) software, we utilized ground control points in the study reaches and acquired imagery using flight lines at various altitudes (200-400 feet above ground level) and oriented both parallel and perpendicular to the river. Our results show that the mean error in the elevations derived from SFM in the upstream reach was 17 centimeters and horizontal accuracy was 6 centimeters when compared to 4 randomly distributed targets surveyed on emergent sandbars. In addition to the targets, multiple transects were
Lougovskaia, Natalia N; Lougovskoi, Andrei A; Bochkov, Yuri A; Batchenko, Galina V; Mudrak, Natalia S; Drygin, Vladimir V; Borisov, Alexander V; Borisov, Vladimir V; Gusev, Anatoly A
2002-12-01
An indirect liquid-phase blocking (LPB) enzyme-linked immunosorbent assay (ELISA) using chicken and rabbit affinity purified immunoglobulin G (IgG) has been developed to detect and estimate avian infectious bronchitis virus (IBV) antigen concentration directly in infected allantoic fluid. The method is based on the principle of binding of specific IgG to the test IBV antigen and the assay of unbound IgG on an antigen-coated ELISA plate. The immunoglobulins are chicken N-terminal S2 peplomeric protein-specific IgG isolated by immunoaffinity chromatography on synthetic peptide coupled to CNBr-activated Sepharose 4B or rabbit polyclonal IgG purified from the serum using Protein A Sepharose 4B. The assay detected all tested IBV strains and field isolates propagated in chicken embryos. Signal to noise ratios were calculated from LPB ELISA absorbance units and a diagnostic threshold was established from the signal to noise ratio frequency distribution of samples positive or negative for IBV by virus titration or reverse transcription polymerase chain reaction. The relative sensitivity of the test ranged between 10(5) and 10(6) median egg infectious doses (EID(50)) for chicken IgG and between 10(3) and 10(4) EID(50) for rabbit IgG, depending on the test strain. The assay is simple and takes less than 3 h to perform. It does not require expensive reagents and can be readily adapted to monitor the IBV antigen concentration in allantoic fluids during propagation of vaccine strains or in samples of freeze-dried, live-attenuated IBV vaccines.
Affine differential geometry analysis of human arm movements.
Flash, Tamar; Handzel, Amir A
2007-06-01
Humans interact with their environment through sensory information and motor actions. These interactions may be understood via the underlying geometry of both perception and action. While the motor space is typically considered by default to be Euclidean, persistent behavioral observations point to a different underlying geometric structure. These observed regularities include the "two-thirds power law", which connects path curvature with velocity, and "local isochrony", which prescribes the relation between movement time and its extent. Starting with these empirical observations, we have developed a mathematical framework based on differential geometry, Lie group theory and Cartan's moving frame method for the analysis of human hand trajectories. We also use this method to identify possible motion primitives, i.e., elementary building blocks from which more complicated movements are constructed. We show that a natural geometric description of continuous repetitive hand trajectories is not Euclidean but equi-affine. Specifically, equi-affine velocity is piecewise constant along movement segments, and movement execution time for a given segment is proportional to its equi-affine arc-length. Using this mathematical framework, we then analyze experimentally recorded drawing movements. To examine movement segmentation and classification, the two fundamental equi-affine differential invariants-equi-affine arc-length and curvature are calculated for the recorded movements. We also discuss the possible role of conic sections, i.e., curves with constant equi-affine curvature, as motor primitives and focus in more detail on parabolas, the equi-affine geodesics. Finally, we explore possible schemes for the internal neural coding of motor commands by showing that the equi-affine framework is compatible with the common model of population coding of the hand velocity vector when combined with a simple assumption on its dynamics. We then discuss several alternative explanations
New unitary affine-Virasoro constructions
Halpern, M.B.; Kiritsis, E.; Obers, N.A.; Poratti, M. ); Yamron, J.P. )
1990-06-20
This paper reports on a quasi-systematic investigation of the Virasoro master equation. The space of all affine-Virasoro constructions is organized by K-conjugation into affine-Virasoro nests, and an estimate of the dimension of the space shows that most solutions await discovery. With consistent ansatze for the master equation, large classes of new unitary nests are constructed, including quadratic deformation nests with continuous conformal weights, and unitary irrational central charge nests, which may dominate unitary rational central charge on compact g.
Affinity driven social networks
NASA Astrophysics Data System (ADS)
Ruyú, B.; Kuperman, M. N.
2007-04-01
In this work we present a model for evolving networks, where the driven force is related to the social affinity between individuals of a population. In the model, a set of individuals initially arranged on a regular ordered network and thus linked with their closest neighbors are allowed to rearrange their connections according to a dynamics closely related to that of the stable marriage problem. We show that the behavior of some topological properties of the resulting networks follows a non trivial pattern.
NASA Astrophysics Data System (ADS)
Dmitrenko, A. V.
2015-11-01
A stream of nonisothermal Newtonian liquid in a circular smooth pipe is considered on the basis of systems of stochastic equations and of the physical law of equivalence of measures between laminar and turbulent motions. Analytical expressions were previously obtained for isothermal flows for the first and second critical Reynolds numbers, critical point, indices of velocity profiles, second-order correlation moments, correlation functions, and spectral functions depending on the parameters of initial turbulence. Analytical expressions, obtained with the use of the earlier derived formulas for the critical Reynolds numbers and the critical points, are presented for the indices of velocity and temperature profiles as functions of the initial turbulence parameters as well as of the Eckert and Prandtl numbers.
Adjoint affine fusion and tadpoles
NASA Astrophysics Data System (ADS)
Urichuk, Andrew; Walton, Mark A.
2016-06-01
We study affine fusion with the adjoint representation. For simple Lie algebras, elementary and universal formulas determine the decomposition of a tensor product of an integrable highest-weight representation with the adjoint representation. Using the (refined) affine depth rule, we prove that equally striking results apply to adjoint affine fusion. For diagonal fusion, a coefficient equals the number of nonzero Dynkin labels of the relevant affine highest weight, minus 1. A nice lattice-polytope interpretation follows and allows the straightforward calculation of the genus-1 1-point adjoint Verlinde dimension, the adjoint affine fusion tadpole. Explicit formulas, (piecewise) polynomial in the level, are written for the adjoint tadpoles of all classical Lie algebras. We show that off-diagonal adjoint affine fusion is obtained from the corresponding tensor product by simply dropping non-dominant representations.
Affinity chromatography: a historical perspective.
Hage, David S; Matsuda, Ryan
2015-01-01
Affinity chromatography is one of the most selective and versatile forms of liquid chromatography for the separation or analysis of chemicals in complex mixtures. This method makes use of a biologically related agent as the stationary phase, which provides an affinity column with the ability to bind selectively and reversibly to a given target in a sample. This review examines the early work in this method and various developments that have lead to the current status of this technique. The general principles of affinity chromatography are briefly described as part of this discussion. Past and recent efforts in the generation of new binding agents, supports, and immobilization methods for this method are considered. Various applications of affinity chromatography are also summarized, as well as the influence this field has played in the creation of other affinity-based separation or analysis methods. PMID:25749941
Nechiporenko, A.A.; Martsevoi, E.P.
1995-07-01
Mathematical simulation has been used to estimate the effect of technological factors on the variation of the temperature and velocity of particles of self-fluxing iron-base powder in a plasma flow of propane-butane combustion products. The influence of the plasma generator arc current, the flow rates of the plasma-forming gases and their relations, the powder particle size, the diameter of the plasma generator nozzle, the powder flow rate, and the spraying distance are analyzed. Optimal spraying conditions are determined for various powder fractions.
Robust, automatic GPS station velocities and velocity time series
NASA Astrophysics Data System (ADS)
Blewitt, G.; Kreemer, C.; Hammond, W. C.
2014-12-01
Automation in GPS coordinate time series analysis makes results more objective and reproducible, but not necessarily as robust as the human eye to detect problems. Moreover, it is not a realistic option to manually scan our current load of >20,000 time series per day. This motivates us to find an automatic way to estimate station velocities that is robust to outliers, discontinuities, seasonality, and noise characteristics (e.g., heteroscedasticity). Here we present a non-parametric method based on the Theil-Sen estimator, defined as the median of velocities vij=(xj-xi)/(tj-ti) computed between all pairs (i, j). Theil-Sen estimators produce statistically identical solutions to ordinary least squares for normally distributed data, but they can tolerate up to 29% of data being problematic. To mitigate seasonality, our proposed estimator only uses pairs approximately separated by an integer number of years (N-δt)<(tj-ti )<(N+δt), where δt is chosen to be small enough to capture seasonality, yet large enough to reduce random error. We fix N=1 to maximally protect against discontinuities. In addition to estimating an overall velocity, we also use these pairs to estimate velocity time series. To test our methods, we process real data sets that have already been used with velocities published in the NA12 reference frame. Accuracy can be tested by the scatter of horizontal velocities in the North American plate interior, which is known to be stable to ~0.3 mm/yr. This presents new opportunities for time series interpretation. For example, the pattern of velocity variations at the interannual scale can help separate tectonic from hydrological processes. Without any step detection, velocity estimates prove to be robust for stations affected by the Mw7.2 2010 El Mayor-Cucapah earthquake, and velocity time series show a clear change after the earthquake, without any of the usual parametric constraints, such as relaxation of postseismic velocities to their preseismic values.
Sensing light and sound velocities with phoxonic crystals
NASA Astrophysics Data System (ADS)
Amoudache, Samira; Moiseyenko, Rayisa; Pennec, Yan; Djafari Rouhani, Bahram; Khater, Antoine; Lucklum, Ralf; Tigrine, Rachid
2014-04-01
We study theoretically the potentiality of dual phononic-photonic (the so-called phoxonic) crystals for liquid sensing applications. We investigate the existence of well-defined features (peaks or dips) in the transmission spectra of acoustic and optical waves and estimate their sensitivity to the sound and light velocities of the liquid environment. Two different sensors are investigated. In the first one, we study the in-plane transmission through a two-dimensional (2D) crystal made of cylindrical holes in a Si substrate where one row of holes is filled with a liquid. In the second one, the out of plane propagation is investigated when considering the transmission of the incident wave perpendicular to a periodic array of holes in a slab. Such ultra compact structure is shown to be a label-free, affinity-based acoustic and optical nanosensor, useful for biosensing applications in which the amount of analyte can be often limited.
Wood, Tamara M.; Gartner, Jeffrey W.
2010-01-01
dispersal of colonies throughout the water column when the water column mixed more easily. RB was used to estimate suspended solids concentrations (SSC). Correlations of depth-integrated SSC with currents or air temperatures suggest that depth-integrated water column mass decreased under conditions of greater water column stability and weaker currents. Results suggest that the use of measured vertical velocity and acoustic backscatter as a surrogate for suspended material has the potential to contribute significant additional insight into dynamics of Aphanizomenon flos-aquae colonies in Upper Klamath Lake, south-central Oregon.
Cesium cation affinities and basicities
NASA Astrophysics Data System (ADS)
Gal, Jean-François; Maria, Pierre-Charles; Massi, Lionel; Mayeux, Charly; Burk, Peeter; Tammiku-Taul, Jaana
2007-11-01
This review focuses on the quantitative data related to cesium cation interaction with neutral or negatively charged ligands. The techniques used for measuring the cesium cation affinity (enthalpies, CCA), and cesium cation basicities (Gibbs free energies, CCB) are briefly described. The quantum chemical calculations methods that were specifically designed for the determination of cesium cation adduct structures and the energetic aspects of the interaction are discussed. The experimental results, obtained essentially from mass spectrometry techniques, and complemented by thermochemical data, are tabulated and commented. In particular, the correlations between cesium cation affinities and lithium cation affinities for the various kinds of ligands (rare gases, polyatomic neutral molecules, among them aromatic compounds and negative ions) serve as a basis for the interpretation of the diverse electrostatic modes of interaction. A brief account of some recent analytical applications of ion/molecule reactions with Cs+, as well as other cationization approaches by Cs+, is given.
"Clickable" agarose for affinity chromatography.
Punna, Sreenivas; Kaltgrad, Eiton; Finn, M G
2005-01-01
Successful purification of biological molecules by affinity chromatography requires the attachment of desired ligands to biocompatible chromatographic supports. The Cu(I)-catalyzed cycloaddition of azides and alkynes-the premier example of "click chemistry"-is an efficient way to make covalent connections among diverse molecules and materials. Both azide and alkyne units are highly selective in their reactivity, being inert to most chemical functionalities and stable to wide ranges of solvent, temperature, and pH. We show that agarose beads bearing alkyne and azide groups can be easily made and are practical precursors to functionalized agarose materials for affinity chromatography.
Overview of affinity tags for protein purification.
Kimple, Michelle E; Brill, Allison L; Pasker, Renee L
2013-01-01
Addition of an affinity tag is a useful method for differentiating recombinant proteins expressed in bacterial and eukaryotic expression systems from the background of total cellular proteins, as well as for detecting protein-protein interactions. This overview describes the historical basis for the development of affinity tags, affinity tags that are commonly used today, how to choose an appropriate affinity tag for a particular purpose, and several recently developed affinity tag technologies that may prove useful in the near future. PMID:24510596
Quantifying Affinity among Chinese Dialects.
ERIC Educational Resources Information Center
Cheng, Chin-Chuan
A study of the relationships between Chinese dialects based on a quantitative measure of dialect affinity is summarized. First, tone values in all the dialect localities available in the early 1970s were used to calculate the dialectal differences in terms of tone height with respect to the "yin and yang" split. In the late 1970s, calculations of…
Affine Contractions on the Plane
ERIC Educational Resources Information Center
Celik, D.; Ozdemir, Y.; Ureyen, M.
2007-01-01
Contractions play a considerable role in the theory of fractals. However, it is not easy to find contractions which are not similitudes. In this study, it is shown by counter examples that an affine transformation of the plane carrying a given triangle onto another triangle may not be a contraction even if it contracts edges, heights or medians.…
Accurate Evaluation Method of Molecular Binding Affinity from Fluctuation Frequency
NASA Astrophysics Data System (ADS)
Hoshino, Tyuji; Iwamoto, Koji; Ode, Hirotaka; Ohdomari, Iwao
2008-05-01
Exact estimation of the molecular binding affinity is significantly important for drug discovery. The energy calculation is a direct method to compute the strength of the interaction between two molecules. This energetic approach is, however, not accurate enough to evaluate a slight difference in binding affinity when distinguishing a prospective substance from dozens of candidates for medicine. Hence more accurate estimation of drug efficacy in a computer is currently demanded. Previously we proposed a concept of estimating molecular binding affinity, focusing on the fluctuation at an interface between two molecules. The aim of this paper is to demonstrate the compatibility between the proposed computational technique and experimental measurements, through several examples for computer simulations of an association of human immunodeficiency virus type-1 (HIV-1) protease and its inhibitor (an example for a drug-enzyme binding), a complexation of an antigen and its antibody (an example for a protein-protein binding), and a combination of estrogen receptor and its ligand chemicals (an example for a ligand-receptor binding). The proposed affinity estimation has proven to be a promising technique in the advanced stage of the discovery and the design of drugs.
Quantification of hydrophobic interaction affinity of colloids
NASA Astrophysics Data System (ADS)
Saini, G.; Nasholm, N.; Wood, B. D.
2009-12-01
Colloids play an important role in a wide variety of disciplines, including water and wastewater treatment, subsurface transport of metals and organic contaminants, migration of fines in oil reservoirs, biocolloid (virus and bacteria) transport in subsurface, and are integral to laboratory transport studies. Although the role of hydrophobicity in adhesion and transport of colloids, particularly bacteria, is well known; there is scarcity of literature regarding hydrophobicity measurement of non-bacterial colloids and other micron-sized particles. Here we detail an experimental approach based on differential partitioning of colloids between two liquid phases (hydrocarbon and buffer) as a measure of the hydrophobic interaction affinity of colloids. This assay, known as Microbial adhesion to hydrocarbons or MATH, is frequently used in microbiology and bacteriology for quantifying the hydrophobicity of microbes. Monodispersed colloids and particles, with sizes ranging from 1 micron to 33 micron, were used for the experiments. A range of hydrophobicity values were observed for different particles. The hydrophobicity results are also verified against water contact angle measurements of these particles. This liquid-liquid partitioning assay is quick, easy-to-perform and requires minimal instrumentation. Estimation of the hydrophobic interaction affinity of colloids would lead to a better understanding of their adhesion to different surfaces and subsequent transport in porous media.
Lectin affinity chromatography of glycolipids
Torres, B.V.; Smith, D.F.
1987-05-01
Since glycolipids (GLs) are either insoluble or form mixed micelles in water, lectin affinity chromatography in aqueous systems has not been applied to their separation. They have overcome this problem by using tetrahydrofuran (THF) in the mobile phase during chromatography. Affinity columns prepared with the GalNAc-specific Helix pomatia agglutinin (HPA) and equilibrated in THF specifically bind the (/sup 3/H)oligosaccharide derived from Forssman GL indicating that the immobilized HPA retained its carbohydrate-binding specificity in this solvent. Intact Forssman GL was bound by the HPA-column equilibrated in THF and was specifically eluted with 0.1 mg/ml GalNAc in THF. Purification of the Forssman GL was achieved when a crude lipid extract of sheep erythrocyte membranes was applied to the HPA-column in THF. Non-specifically bound GLs were eluted from the column using a step gradient of aqueous buffer in THF, while the addition of GalNAc was required to elute the specifically bound GLs. Using this procedure the A-active GLs were purified from a crude lipid extract of type A human erythrocytes in a single chromatographic step. The use of solvents that maintain carbohydrate-binding specificity and lipid solubility will permit the application of affinity chromatography on immobilized carbohydrate-binding proteins to intact GLs.
New GNSS velocity field and preliminary velocity model for Ecuador
NASA Astrophysics Data System (ADS)
Luna-Ludeña, Marco P.; Staller, Alejandra; Gaspar-Escribano, Jorge M.; Belén Benito, M.
2016-04-01
In this work, we present a new preliminary velocity model of Ecuador based on the GNSS data of the REGME network (continuous monitoring GNSS network). To date, there is no velocity model available for the country. The only existing model in the zone is the regional model VEMOS2009 for South America and Caribbean (Drewes and Heidbach, 2012). This model was developed from the SIRGAS station positions, the velocities of the SIRGAS-CON stations, and several geodynamics projects performed in the region. Just two continuous GNSS (cGNSS) stations of Ecuador were taking into account in the VEMOS2009 model. The first continuous station of the REGME network was established in 2008. At present, it is composed by 32 continuous GNSS stations, covering the country. All the stations provided data during at least two years. We processed the data of the 32 GNSS stations of REGME for the 2008-2014 period, as well as 20 IGS stations in order to link to the global reference frame IGb08 (ITRF2008). GPS data were processed using Bernese 5.0 software (Dach et al., 2007). We obtained and analyzed the GNSS coordinate time series of the 32 REGME stations and we calculated the GPS-derived horizontal velocity field of the country. Velocities in ITRF2008 were transformed into a South American fixed reference frame, using the Euler pole calculated from 8 cGNSS stations throughout this plate. Our velocity field is consistent with the tectonics of the country and contributes to a better understanding of it. From the horizontal velocity field, we determined a preliminary model using the kriging geostatistical technique. To check the results we use the cross-validation method. The differences between the observed and estimated values range from ± 5 mm. This is a new velocity model obtained from GNSS data for Ecuador.
On the electron affinity of the oxygen atom
NASA Technical Reports Server (NTRS)
Bauschlicher, C. W., Jr.; Langhoff, S. R.; Partridge, H.; Taylor, P. R.
1986-01-01
The electron affinity of oxygen is computed to be 1.287 eV, at the full CI level using a 6s5p3d 2f Slater-type orbital basis and correlating only the 2p electrons. The best CASSCF-MRCI result including only 2p correlation is 1.263 eV. However, inclusion of 2s intrashell and 2s2p intershell coorelation increases the computed EA to 1.290 eV at the CASSCF-MRCI level. At the full CI basis set limit, the 2s contribution to the electron affinity is estimated to be as large as 0.1 eV. The higher excitation contribution to the electron affinity is found to increase substantially with basis set completeness, especially when the 2s electrons are correlated. Relativistic effects are shown to make a small (less than 0.01 eV) change in the EA.
On the electron affinity of the oxygen atom
NASA Technical Reports Server (NTRS)
Bauschlicher, C. W., Jr.; Langhoff, S. R.; Partridge, H.; Taylor, P. R.
1986-01-01
The electron affinity (EA) of oxygen is computed to be 1.287 eV, using 2p electron full configuration-interaction (CI) wave functions expanded in a 6s5p3d2f Slater-type orbital basis. The best complete active space self-consistent field - multireference CI (CASSCF-MRCI) result including only 2p correlation is 1.263 eV. However, inclusion of 2s intrashell and 2s2p intershell correlation increases the computed EA to 1.290 at the CASSCF-MRCI level. At the full CI basis set limit, the 2s contribution to the electron affinity is estimated to be as large as 0.1 eV. This study clearly establishes the synergistic effect between the higher excitations and basis set completeness on the electron affinity when the 2s electrons are correlated.
Velocity selection in coupled-map lattices
NASA Astrophysics Data System (ADS)
Parekh, Nita; Puri, Sanjay
1993-02-01
We investigate the phenomenon of velocity selection for traveling wave fronts in a class of coupled-map lattices, derived by discretizations of the Fisher equation [Ann. Eugenics 7, 355 (1937)]. We find that the velocity selection can be understood in terms of a discrete analog of the marginal-stability hypothesis. A perturbative approach also enables us to estimate the selected velocity accurately for small values of the discretization mesh sizes.
NASA Astrophysics Data System (ADS)
Brungard, C. W.; Boettinger, J. L.; Hipps, L.
2015-12-01
Disturbance of lacustrine and alluvial soils could increase aeolian dust emissions in the eastern Great Basin, but little is known about the susceptibility of these land surfaces to wind erosion. Threshold friction velocity (u*t ), a necessary parameter to estimate wind erosion potential, is difficult to accurately measure; methods to estimate u*t from alternate measurements would be useful. We measured u*t and sediment production rate with a portable wind tunnel, and quantified relationships between u*t and eleven easier-to-measure soil surface properties for both undisturbed and disturbed lacustrine and alluvial soils in Snake Valley, Utah. Soil surface type and disturbance significantly influenced u*t, sediment production rate, and the relationships between u*t and easier-to-measure soil surface properties. Only soils with surficial rock fragments and weak physical crusts reached u*t before disturbance, whereas all surface types reached u*t following disturbance. Soils with weak physical crusts had the lowest average u*t and highest average sediment production rate before and after disturbance. Surprisingly, however, disturbance reduced sediment production rate. Soils with weak physical crusts and surficial rock cover are likely the most susceptible to wind erosion and subsequent dust generation both before and after disturbance. Silt concentration and penetrometer resistance were significant predictors of u*t in undisturbed soils with weak physical crusts and surficial rock cover. Following disturbance, clay concentration and aggregate stability were significant predictors for soils with hard salt crusts and surficial rock cover. Prediction of u*t using alternate measurements is promising, but measurement uncertainty must be considered.
Two-parameter twisted quantum affine algebras
NASA Astrophysics Data System (ADS)
Jing, Naihuan; Zhang, Honglian
2016-09-01
We establish Drinfeld realization for the two-parameter twisted quantum affine algebras using a new method. The Hopf algebra structure for Drinfeld generators is given for both untwisted and twisted two-parameter quantum affine algebras, which include the quantum affine algebras as special cases.
Tangential velocity measurement using interferometric MTI radar
Doerry, Armin W.; Mileshosky, Brian P.; Bickel, Douglas L.
2006-01-03
Radar systems use time delay measurements between a transmitted signal and its echo to calculate range to a target. Ranges that change with time cause a Doppler offset in phase and frequency of the echo. Consequently, the closing velocity between target and radar can be measured by measuring the Doppler offset of the echo. The closing velocity is also known as radial velocity, or line-of-sight velocity. Doppler frequency is measured in a pulse-Doppler radar as a linear phase shift over a set of radar pulses during some Coherent Processing Interval (CPI). An Interferometric Moving Target Indicator (MTI) radar can be used to measure the tangential velocity component of a moving target. Multiple baselines, along with the conventional radial velocity measurement, allow estimating the true 3-D velocity of a target.
Affinity Purification of Sequence-Specific DNA Binding Proteins
NASA Astrophysics Data System (ADS)
Kadonaga, James T.; Tjian, Robert
1986-08-01
We describe a method for affinity purification of sequence-specific DNA binding proteins that is fast and effective. Complementary chemically synthesized oligodeoxynucleotides that contain a recognition site for a sequence-specific DNA binding protein are annealed and ligated to give oligomers. This DNA is then covalently coupled to Sepharose CL-2B with cyanogen bromide to yield the affinity resin. A partially purified protein fraction is combined with competitor DNA and subsequently passed through the DNA-Sepharose resin. The desired sequence-specific DNA binding protein is purified because it preferentially binds to the recognition sites in the affinity resin rather than to the nonspecific competitor DNA in solution. For example, a protein fraction that is enriched for transcription factor Sp1 can be further purified 500- to 1000-fold by two sequential affinity chromatography steps to give Sp1 of an estimated 90% homogeneity with 30% yield. In addition, the use of tandem affinity columns containing different protein binding sites allows the simultaneous purification of multiple DNA binding proteins from the same extract. This method provides a means for the purification of rare sequence-specific DNA binding proteins, such as Sp1 and CAAT-binding transcription factor.
Kriging interpolating cosmic velocity field
NASA Astrophysics Data System (ADS)
Yu, Yu; Zhang, Jun; Jing, Yipeng; Zhang, Pengjie
2015-10-01
Volume-weighted statistics of large-scale peculiar velocity is preferred by peculiar velocity cosmology, since it is free of the uncertainties of galaxy density bias entangled in observed number density-weighted statistics. However, measuring the volume-weighted velocity statistics from galaxy (halo/simulation particle) velocity data is challenging. Therefore, the exploration of velocity assignment methods with well-controlled sampling artifacts is of great importance. For the first time, we apply the Kriging interpolation to obtain the volume-weighted velocity field. Kriging is a minimum variance estimator. It predicts the most likely velocity for each place based on the velocity at other places. We test the performance of Kriging quantified by the E-mode velocity power spectrum from simulations. Dependences on the variogram prior used in Kriging, the number nk of the nearby particles to interpolate, and the density nP of the observed sample are investigated. First, we find that Kriging induces 1% and 3% systematics at k ˜0.1 h Mpc-1 when nP˜6 ×1 0-2(h-1 Mpc )-3 and nP˜6 ×1 0-3(h-1 Mpc )-3 , respectively. The deviation increases for decreasing nP and increasing k . When nP≲6 ×1 0-4(h-1 Mpc )-3 , a smoothing effect dominates small scales, causing significant underestimation of the velocity power spectrum. Second, increasing nk helps to recover small-scale power. However, for nP≲6 ×1 0-4(h-1 Mpc )-3 cases, the recovery is limited. Finally, Kriging is more sensitive to the variogram prior for a lower sample density. The most straightforward application of Kriging on the cosmic velocity field does not show obvious advantages over the nearest-particle method [Y. Zheng, P. Zhang, Y. Jing, W. Lin, and J. Pan, Phys. Rev. D 88, 103510 (2013)] and could not be directly applied to cosmology so far. However, whether potential improvements may be achieved by more delicate versions of Kriging is worth further investigation.
Cosmic string induced peculiar velocities
NASA Technical Reports Server (NTRS)
Van Dalen, Anthony; Schramm, David N.
1988-01-01
This paper considers the scenario of a flat universe with a network of heavy cosmic strings as the primordial fluctuation spectrum. The joint probability of finding streaming velocities of at least 600 km/s on large scales and local peculiar velocities of less than 800 km/s is calculated. It is shown how the effects of loops breaking up and being born with a spectrum of sizes can be estimated. It is found that to obtain large-scale streaming velocities of at least 600 km/s, it is necessary that either a large value for beta G mu exist or the effect of loop fissioning and production details be considerable.
Stochastic characterization of mesoscale seismic velocity heterogeneity in Long Beach, California
NASA Astrophysics Data System (ADS)
Nakata, Nori; Beroza, Gregory C.
2015-12-01
Earth's seismic velocity structure is heterogeneous at all scales, and mapping that heterogeneity provides insight into the processes that create it. At large scale lengths, seismic tomography is used to map Earth structure deterministically. At small scale lengths, structure can be imaged deterministically, but because it is impractical to image short-wavelength heterogeneity everywhere, we often resort to statistical methods to depict its variability. In this study, we develop random-field model representations of a 3-D P-wave velocity model at Long Beach, California, estimated from dense-array recordings of the ambient seismic wavefield. We focus on heterogeneity at the mesoscale, which is smaller than 10+ km scale of regional tomography but larger than the micro scale of borehole measurements. We explore four ellipsoidally anisotropic heterogeneity models, including von Kármán, Gaussian, self-affine and Kummer models, based on their autocorrelation functions. We find that the von Kármán model fits the imaged velocity model best among these options with a correlation length in the horizontal direction about five times greater than in the vertical direction, and with strong small-scale length variations. We validate our results by showing that our model accurately predicts the observed decay of scattered waves in the coda of a nearby earthquake, suggesting that quantitative measures of velocity variability will be useful for predicting high-frequency ground motion in earthquakes.
A method for determining critical swimming velocity.
Takahashi, S; Wakayoshi, K; Hayashi, A; Sakaguchi, Y; Kitagawa, K
2009-02-01
The purpose of this study was to determine whether the critical swimming velocity (Vcri) estimated by the swimming velocity for a distance of 300 m at maximal effort breaststroke reflects the maximal lactate steady state (MLSS). Twelve trained swimmers swam 50 m, 300 m and 2 000 m at maximal effort for determination of Vcri that averaged 1.167 +/- 0.045 m . sec (-1). Since Vcri was equivalent to 90.5 % of the mean swimming velocity over the distance of 300 m at maximal effort, the swimming velocity obtained by multiplying the swimming velocity for the distance of 300 m of each subject by 90.5 % was taken to be 100 % of the predicted critical swimming velocity (Vcri-pred). Then, in an MLSS test, the subjects were instructed to swim breaststroke 2 000 m (5 x 400 m) at three constant velocities (98 %, 100 %, and 102 % of Vcri-pred), interrupted by four short rest periods from 30 to 45 seconds for blood sampling and heart rate measurement. As a result, the blood lactate concentration at 100 % Vcri-pred showed a higher steady state than the slow velocity, but at high velocity did not show the steady state. In conclusion, we can accurately estimate the Vcri for breaststroke by a one-time 300-m maximal effort swimming test.
The maximal affinity of ligands
Kuntz, I. D.; Chen, K.; Sharp, K. A.; Kollman, P. A.
1999-01-01
We explore the question of what are the best ligands for macromolecular targets. A survey of experimental data on a large number of the strongest-binding ligands indicates that the free energy of binding increases with the number of nonhydrogen atoms with an initial slope of ≈−1.5 kcal/mol (1 cal = 4.18 J) per atom. For ligands that contain more than 15 nonhydrogen atoms, the free energy of binding increases very little with relative molecular mass. This nonlinearity is largely ascribed to nonthermodynamic factors. An analysis of the dominant interactions suggests that van der Waals interactions and hydrophobic effects provide a reasonable basis for understanding binding affinities across the entire set of ligands. Interesting outliers that bind unusually strongly on a per atom basis include metal ions, covalently attached ligands, and a few well known complexes such as biotin–avidin. PMID:10468550
Engineering antibody affinity and specificity.
Webster, D M; Roberts, S; Cheetham, J C; Griest, R; Rees, A R
1988-01-01
A combination of ab initio calculations, "knowledge-based prediction", molecular graphics and site-directed mutagenesis has enabled us to probe the molecular details of antibody:antigen recognition and binding and to alter the affinity and specificity of an antibody for its antigen. The significance of electrostatic hydrogen bonding, hydrophilic/hydrophobic patch matching and van der Waals interactions as well as CDR:CDR interactions are discussed in relation to the results of site-directed mutagenesis experiments on the anti-lysozyme antibody Gloop2. The ability to generate reconstructed antibodies, chimeric antibodies, catalytic antibodies and the use of modelled antibodies for the design of drugs is discussed. PMID:3209295
Proton affinities of hydrated molecules
NASA Astrophysics Data System (ADS)
Valadbeigi, Younes
2016-09-01
Proton affinities (PA) of non-hydrated, M, and hydrated forms, M(H2O)1,2,3, of 20 organic molecules including alcohols, ethers, aldehydes, ketones and amines were calculated by the B3LYP/6-311++G(d,p) method. For homogeneous families, linear correlations were observed between PAs of the M(H2O)1,2,3 and the PAs of the non-hydrated molecules. Also, the absolute values of the hydration enthalpies of the protonated molecules decreased linearly with the PAs. The correlation functions predicted that for an amine with PA < 1100 kJ/mol the PA(M(H2O)) is larger than the corresponding PA, while for an amine with PA > 1100 kJ/mol the PA(M(H2O)) is smaller than the PA.
Conformal field theory on affine Lie groups
Clubok, K.S.
1996-04-01
Working directly on affine Lie groups, we construct several new formulations of the WZW model, the gauged WZW model, and the generic affine-Virasoro action. In one formulation each of these conformal field theories (CFTs) is expressed as a one-dimensional mechanical system whose variables are coordinates on the affine Lie group. When written in terms of the affine group element, this formulation exhibits a two-dimensional WZW term. In another formulation each CFT is written as a two-dimensional field theory, with a three- dimensional WZW term, whose fields are coordinates on the affine group. On the basis of these equivalent formulations, we develop a translation dictionary in which the new formulations on the affine Lie group are understood as mode formulations of the conventional formulations on the Lie group. Using this dictionary, we also express each CFT as a three-dimensional field theory on the Lie group with a four-dimensional WZW term. 36 refs.
Estimating synchronization signal phase
NASA Astrophysics Data System (ADS)
Lyons, Robert G.; Lord, John D.
2015-03-01
To read a watermark from printed images requires that the watermarking system read correctly after affine distortions. One way to recover from affine distortions is to add a synchronization signal in the Fourier frequency domain and use this synchronization signal to estimate the applied affine distortion. Using the Fourier Magnitudes one can estimate the linear portion of the affine distortion. To estimate the translation one must first estimate the phase of the synchronization signal and then use phase correlation to estimate the translation. In this paper we provide a new method to measure the phase of the synchronization signal using only the data from the complex Fourier domain. This data is used to compute the linear portion, so it is quite convenient to estimate the phase without further data manipulation. The phase estimation proposed in this paper is computationally simple and provides a significant computational advantage over previous methods while maintaining similar accuracy. In addition, the phase estimation formula gives a general way to interpolate images in the complex frequency domain.
Structural determinants of sigma receptor affinity
Largent, B.L.; Wikstroem, H.G.; Gundlach, A.L.; Snyder, S.H.
1987-12-01
The structural determinants of sigma receptor affinity have been evaluated by examining a wide range of compounds related to opioids, neuroleptics, and phenylpiperidine dopaminergic structures for affinity at sigma receptor-binding sites labeled with (+)-(/sup 3/H)3-PPP. Among opioid compounds, requirements for sigma receptor affinity differ strikingly from the determinants of affinity for conventional opiate receptors. Sigma sites display reverse stereoselectivity to classical opiate receptors. Multi-ringed opiate-related compounds such as morphine and naloxone have negligible affinity for sigma sites, with the highest sigma receptor affinity apparent for benzomorphans which lack the C ring of opioids. Highest affinity among opioids and other compounds occurs with more lipophilic N-substituents. This feature is particularly striking among the 3-PPP derivatives as well as the opioids. The butyrophenone haloperidol is the most potent drug at sigma receptors we have detected. Among the series of butyrophenones, receptor affinity is primarily associated with the 4-phenylpiperidine moiety. Conformational calculations for various compounds indicate a fairly wide range of tolerance for distances between the aromatic ring and the amine nitrogen, which may account for the potency at sigma receptors of structures of considerable diversity. Among the wide range of structures that bind to sigma receptor-binding sites, the common pharmacophore associated with high receptor affinity is a phenylpiperidine with a lipophilic N-substituent.
Non-affine deformations in polymer hydrogels
Wen, Qi; Basu, Anindita; Janmey, Paul A.; Yodh, A. G.
2012-01-01
Most theories of soft matter elasticity assume that the local strain in a sample after deformation is identical everywhere and equal to the macroscopic strain, or equivalently that the deformation is affine. We discuss the elasticity of hydrogels of crosslinked polymers with special attention to affine and non-affine theories of elasticity. Experimental procedures to measure non-affine deformations are also described. Entropic theories, which account for gel elasticity based on stretching out individual polymer chains, predict affine deformations. In contrast, simulations of network deformation that result in bending of the stiff constituent filaments generally predict non-affine behavior. Results from experiments show significant non-affine deformation in hydrogels even when they are formed by flexible polymers for which bending would appear to be negligible compared to stretching. However, this finding is not necessarily an experimental proof of the non-affine model for elasticity. We emphasize the insights gained from experiments using confocal rheoscope and show that, in addition to filament bending, sample micro-inhomogeneity can be a significant alternative source of non-affine deformation. PMID:23002395
A Novel Vertex Affinity for Community Detection
Yoo, Andy; Sanders, Geoffrey; Henson, Van; Vassilevski, Panayot
2015-10-05
We propose a novel vertex affinity measure in this paper. The new vertex affinity quantifies the proximity between two vertices in terms of their clustering strength and is ideal for such graph analytics applications as community detection. We also developed a framework that combines simple graph searches and resistance circuit formulas to compute the vertex affinity efficiently. We study the properties of the new affinity measure empirically in comparison to those of other popular vertex proximity metrics. Our results show that the existing metrics are ill-suited for community detection due to their lack of fundamental properties that are essential for correctly capturing inter- and intra-cluster vertex proximity.
Background correction using dinucleotide affinities improves the performance of GCRMA
Gharaibeh, Raad Z; Fodor, Anthony A; Gibas, Cynthia J
2008-01-01
Background High-density short oligonucleotide microarrays are a primary research tool for assessing global gene expression. Background noise on microarrays comprises a significant portion of the measured raw data, which can have serious implications for the interpretation of the generated data if not estimated correctly. Results We introduce an approach to calculate probe affinity based on sequence composition, incorporating nearest-neighbor (NN) information. Our model uses position-specific dinucleotide information, instead of the original single nucleotide approach, and adds up to 10% to the total variance explained (R2) when compared to the previously published model. We demonstrate that correcting for background noise using this approach enhances the performance of the GCRMA preprocessing algorithm when applied to control datasets, especially for detecting low intensity targets. Conclusion Modifying the previously published position-dependent affinity model to incorporate dinucleotide information significantly improves the performance of the model. The dinucleotide affinity model enhances the detection of differentially expressed genes when implemented as a background correction procedure in GeneChip preprocessing algorithms. This is conceptually consistent with physical models of binding affinity, which depend on the nearest-neighbor stacking interactions in addition to base-pairing. PMID:18947404
Angular velocity discrimination
NASA Technical Reports Server (NTRS)
Kaiser, Mary K.
1990-01-01
Three experiments designed to investigate the ability of naive observers to discriminate rotational velocities of two simultaneously viewed objects are described. Rotations are constrained to occur about the x and y axes, resulting in linear two-dimensional image trajectories. The results indicate that observers can discriminate angular velocities with a competence near that for linear velocities. However, perceived angular rate is influenced by structural aspects of the stimuli.
Fiber Optic Velocity Interferometry
Neyer, Barry T.
1988-04-01
This paper explores the use of a new velocity measurement technique that has several advantages over existing techniques. It uses an optical fiber to carry coherent light to and from a moving target. A Fabry-Perot interferometer, formed by a gradient index lens and the moving target, produces fringes with a frequency proportional to the target velocity. This technique can measure velocities up to 10 km/s, is accurate, portable, and completely noninvasive.
Structure of classical affine and classical affine fractional W-algebras
Suh, Uhi Rinn
2015-01-15
We introduce a classical BRST complex (See Definition 3.2.) and show that one can construct a classical affine W-algebra via the complex. This definition clarifies that classical affine W-algebras can be considered as quasi-classical limits of quantum affine W-algebras. We also give a definition of a classical affine fractional W-algebra as a Poisson vertex algebra. As in the classical affine case, a classical affine fractional W-algebra has two compatible λ-brackets and is isomorphic to an algebra of differential polynomials as a differential algebra. When a classical affine fractional W-algebra is associated to a minimal nilpotent, we describe explicit forms of free generators and compute λ-brackets between them. Provided some assumptions on a classical affine fractional W-algebra, we find an infinite sequence of integrable systems related to the algebra, using the generalized Drinfel’d and Sokolov reduction.
Methods for Improving Aptamer Binding Affinity.
Hasegawa, Hijiri; Savory, Nasa; Abe, Koichi; Ikebukuro, Kazunori
2016-01-01
Aptamers are single stranded oligonucleotides that bind a wide range of biological targets. Although aptamers can be isolated from pools of random sequence oligonucleotides using affinity-based selection, aptamers with high affinities are not always obtained. Therefore, further refinement of aptamers is required to achieve desired binding affinities. The optimization of primary sequences and stabilization of aptamer conformations are the main approaches to refining the binding properties of aptamers. In particular, sequence optimization using combined in silico sequence recombinations and in vitro functional evaluations is effective for the improvement of binding affinities, however, the binding affinities of aptamers are limited by the low hydrophobicity of nucleic acids. Accordingly, introduction of hydrophobic moieties into aptamers expands the diversity of interactions between aptamers and targets. Moreover, construction of multivalent aptamers by connecting aptamers that recognize distinct epitopes is an attractive approach to substantial increases in binding affinity. In addition, binding affinities can be tuned by optimizing the scaffolds of multivalent constructs. In this review, we summarize the various techniques for improving the binding affinities of aptamers. PMID:27043498
Improving image segmentation by learning region affinities
Prasad, Lakshman; Yang, Xingwei; Latecki, Longin J
2010-11-03
We utilize the context information of other regions in hierarchical image segmentation to learn new regions affinities. It is well known that a single choice of quantization of an image space is highly unlikely to be a common optimal quantization level for all categories. Each level of quantization has its own benefits. Therefore, we utilize the hierarchical information among different quantizations as well as spatial proximity of their regions. The proposed affinity learning takes into account higher order relations among image regions, both local and long range relations, making it robust to instabilities and errors of the original, pairwise region affinities. Once the learnt affinities are obtained, we use a standard image segmentation algorithm to get the final segmentation. Moreover, the learnt affinities can be naturally unutilized in interactive segmentation. Experimental results on Berkeley Segmentation Dataset and MSRC Object Recognition Dataset are comparable and in some aspects better than the state-of-art methods.
Park, Dae Woo; Kruger, Grant H; Rubin, Jonathan M; Hamilton, James; Gottschalk, Paul; Dodde, Robert E; Shih, Albert J; Weitzel, William F
2013-10-01
This study investigated the use of ultrasound speckle decorrelation- and correlation-based lateral speckle-tracking methods for transverse and longitudinal blood velocity profile measurement, respectively. By studying the blood velocity gradient at the vessel wall, vascular wall shear stress, which is important in vascular physiology as well as the pathophysiologic mechanisms of vascular diseases, can be obtained. Decorrelation-based blood velocity profile measurement transverse to the flow direction is a novel approach, which provides advantages for vascular wall shear stress measurement over longitudinal blood velocity measurement methods. Blood flow velocity profiles are obtained from measurements of frame-to-frame decorrelation. In this research, both decorrelation and lateral speckle-tracking flow estimation methods were compared with Poiseuille theory over physiologic flows ranging from 50 to 1000 mm/s. The decorrelation flow velocity measurement method demonstrated more accurate prediction of the flow velocity gradient at the wall edge than the correlation-based lateral speckle-tracking method. The novelty of this study is that speckle decorrelation-based flow velocity measurements determine the blood velocity across a vessel. In addition, speckle decorrelation-based flow velocity measurements have higher axial spatial resolution than Doppler ultrasound measurements to enable more accurate measurement of blood velocity near a vessel wall and determine the physiologically important wall shear.
Stepwise shockwave velocity determinator
NASA Technical Reports Server (NTRS)
Roth, Timothy E.; Beeson, Harold
1992-01-01
To provide an uncomplicated and inexpensive method for measuring the far-field velocity of a surface shockwave produced by an explosion, a stepwise shockwave velocity determinator (SSVD) was developed. The velocity determinator is constructed of readily available materials and works on the principle of breaking discrete sensors composed of aluminum foil contacts. The discrete sensors have an average breaking threshold of approximately 7 kPa. An incremental output step of 250 mV is created with each foil contact breakage and is logged by analog-to-digital instrumentation. Velocity data obtained from the SSVD is within approximately 11 percent of the calculated surface shockwave velocity of a muzzle blast from a 30.06 rifle.
Isotope shift in the electron affinity of lithium
Bubin, Sergiy; Komasa, Jacek; Stanke, Monika; Adamowicz, Ludwik
2009-12-21
Very accurate electron affinity (EA) calculations of {sup 6}Li and {sup 7}Li (and {sup {infinity}L}i) have been performed using explicitly correlated Gaussian functions and a variational approach that explicitly includes the nuclear motion in the calculations (i.e., the approach that does not assume the Born-Oppenheimer approximation). The leading relativistic and quantum electrodynamics corrections to the electron affinities were also calculated. The results are the most accurate theoretical values obtained for the studied systems to date. Our best estimates of the {sup 7}Li and {sup 6}Li EAs are 4984.9842(30) and 4984.9015(30) cm{sup -1}, respectively, and of the {sup 7}Li/{sup 6}Li EA isotope shift is 0.0827 cm{sup -1}.
Isotope shift in the electron affinity of lithium.
Bubin, Sergiy; Komasa, Jacek; Stanke, Monika; Adamowicz, Ludwik
2009-12-21
Very accurate electron affinity (EA) calculations of (6)Li and (7)Li (and (infinity)Li) have been performed using explicitly correlated Gaussian functions and a variational approach that explicitly includes the nuclear motion in the calculations (i.e., the approach that does not assume the Born-Oppenheimer approximation). The leading relativistic and quantum electrodynamics corrections to the electron affinities were also calculated. The results are the most accurate theoretical values obtained for the studied systems to date. Our best estimates of the (7)Li and (6)Li EAs are 4984.9842(30) and 4984.9015(30) cm(-1), respectively, and of the (7)Li/(6)Li EA isotope shift is 0.0827 cm(-1).
NASA Astrophysics Data System (ADS)
Zhao, Shitie; Gao, Xianwen
2016-08-01
A robust adaptive control is proposed for a class of single-input single-output non-affine nonlinear systems. In order to approximate the unknown nonlinear function, a novel affine-type neural network is used, and then to compensate the approximation error and external disturbance a robust control term is employed. By Lyapunov stability analysis for the closed-loop system, it is proved that tracking errors asymptotically converge to zero. Moreover, an observer is designed to estimate the system states because all the states may not be available for measurements. Furthermore, the adaptation laws of neural networks and the robust controller are given out based on the Lyapunov stability theory. Finally, two simulation examples are presented to demonstrate the effectiveness of the proposed control method.
NASA Astrophysics Data System (ADS)
Parker, E. Horry, Jr.; Hawman, Robert B.; Fischer, Karen M.; Wagner, Lara S.
2016-09-01
Deconvolved waveforms for two earthquakes (Mw: 6.0 and 5.8) show clear postcritical SsPmp arrivals for broadband stations deployed across the coastal plain of Georgia, allowing mapping of crustal thickness in spite of strong reverberations generated by low-velocity sediments. Precritical SsPmp arrivals are also identified. For a basement in which velocity increases linearly with depth, a bootstrapped grid search suggests an average basement velocity of 6.5 ± 0.1 km/s and basement thickness of 29.8 ± 2.0 km. Corresponding normal-incidence Moho two-way times (including sediments) are 10.6 ± 0.6 s, consistent with times for events interpreted as Moho reflections on coincident active-source reflection profiles. Modeling of an underplated mafic layer (Vp = 7.2-7.4 km/s) using travel time constraints from SsPmp data and vertical-incidence Moho reflection times yields a total basement thickness of 30-35 km and average basement velocity of 6.35-6.65 km/s for an underplate thickness of 0-15 km.
Affinity Proteomics in the mountains: Alpbach 2015.
Taussig, Michael J
2016-09-25
The 2015 Alpbach Workshop on Affinity Proteomics, organised by the EU AFFINOMICS consortium, was the 7th workshop in this series. As in previous years, the focus of the event was the current state of affinity methods for proteome analysis, including complementarity with mass spectrometry, progress in recombinant binder production methods, alternatives to classical antibodies as affinity reagents, analysis of proteome targets, industry focus on biomarkers, and diagnostic and clinical applications. The combination of excellent science with Austrian mountain scenery and winter sports engender an atmosphere that makes this series of workshops exceptional. The articles in this Special Issue represent a cross-section of the presentations at the 2015 meeting. PMID:27118167
Aptamers in Affinity Separations: Stationary Separation
NASA Astrophysics Data System (ADS)
Ravelet, Corinne; Peyrin, Eric
The use of DNA or RNA aptamers as tools in analytical chemistry is a very promising field of research because of their capabilities to bind specifically the target molecules with an affinity similar to that of antibodies. Notably, they appear to be of great interest as target-specific ligands for the separation and capture of various analytes in affinity chromatography and related affinity-based methods such as magnetic bead technology. In this chapter, the recent developments of these aptamer-based separation/capture approaches are addressed.
ERIC Educational Resources Information Center
Gillespie, A.
1975-01-01
Describes a method for the determination of the velocity of sound using a dual oscilloscope on which is displayed the sinusoidal input into a loudspeaker and the signal picked up by a microphone. (GS)
Porterio, J.L.F.; Page, R.H.; Przirembel, C.E.G.
1984-02-01
The development of the wake velocity profile behind a cylindrical blunt based body aligned with a subsonic uniform stream was experimentally investigated as a function of the momentum thickness of the approaching boundary layer and the transfer of mass into the recirculating region. Tests were conducted at M = 0.11 in an interference-free wind tunnel utilizing an upstream support system. Results indicate that the width of the wake increases with the thickness of the boundary layer while the velocity at the centerline decreases. Near wake mass transfer was found to alter centerline velocities while the width of the wake was not significantly altered. Wake centerline velocity development as a function of boundary layer thickness is presented for distances up to three diameters from the base.
NASA Technical Reports Server (NTRS)
1988-01-01
A video tape related to orbital debris research is presented. The video tape covers the process of loading a High Velocity Gas Gun and firing it into a mounted metal plate. The process is then repeated in slow motion.
Predicting Vertical Jump Height from Bar Velocity
García-Ramos, Amador; Štirn, Igor; Padial, Paulino; Argüelles-Cienfuegos, Javier; De la Fuente, Blanca; Strojnik, Vojko; Feriche, Belén
2015-01-01
The objective of the study was to assess the use of maximum (Vmax) and final propulsive phase (FPV) bar velocity to predict jump height in the weighted jump squat. FPV was defined as the velocity reached just before bar acceleration was lower than gravity (-9.81 m·s-2). Vertical jump height was calculated from the take-off velocity (Vtake-off) provided by a force platform. Thirty swimmers belonging to the National Slovenian swimming team performed a jump squat incremental loading test, lifting 25%, 50%, 75% and 100% of body weight in a Smith machine. Jump performance was simultaneously monitored using an AMTI portable force platform and a linear velocity transducer attached to the barbell. Simple linear regression was used to estimate jump height from the Vmax and FPV recorded by the linear velocity transducer. Vmax (y = 16.577x - 16.384) was able to explain 93% of jump height variance with a standard error of the estimate of 1.47 cm. FPV (y = 12.828x - 6.504) was able to explain 91% of jump height variance with a standard error of the estimate of 1.66 cm. Despite that both variables resulted to be good predictors, heteroscedasticity in the differences between FPV and Vtake-off was observed (r2 = 0.307), while the differences between Vmax and Vtake-off were homogenously distributed (r2 = 0.071). These results suggest that Vmax is a valid tool for estimating vertical jump height in a loaded jump squat test performed in a Smith machine. Key points Vertical jump height in the loaded jump squat can be estimated with acceptable precision from the maximum bar velocity recorded by a linear velocity transducer. The relationship between the point at which bar acceleration is less than -9.81 m·s-2 and the real take-off is affected by the velocity of movement. Mean propulsive velocity recorded by a linear velocity transducer does not appear to be optimal to monitor ballistic exercise performance. PMID:25983572
Predicting vertical jump height from bar velocity.
García-Ramos, Amador; Štirn, Igor; Padial, Paulino; Argüelles-Cienfuegos, Javier; De la Fuente, Blanca; Strojnik, Vojko; Feriche, Belén
2015-06-01
The objective of the study was to assess the use of maximum (Vmax) and final propulsive phase (FPV) bar velocity to predict jump height in the weighted jump squat. FPV was defined as the velocity reached just before bar acceleration was lower than gravity (-9.81 m·s(-2)). Vertical jump height was calculated from the take-off velocity (Vtake-off) provided by a force platform. Thirty swimmers belonging to the National Slovenian swimming team performed a jump squat incremental loading test, lifting 25%, 50%, 75% and 100% of body weight in a Smith machine. Jump performance was simultaneously monitored using an AMTI portable force platform and a linear velocity transducer attached to the barbell. Simple linear regression was used to estimate jump height from the Vmax and FPV recorded by the linear velocity transducer. Vmax (y = 16.577x - 16.384) was able to explain 93% of jump height variance with a standard error of the estimate of 1.47 cm. FPV (y = 12.828x - 6.504) was able to explain 91% of jump height variance with a standard error of the estimate of 1.66 cm. Despite that both variables resulted to be good predictors, heteroscedasticity in the differences between FPV and Vtake-off was observed (r(2) = 0.307), while the differences between Vmax and Vtake-off were homogenously distributed (r(2) = 0.071). These results suggest that Vmax is a valid tool for estimating vertical jump height in a loaded jump squat test performed in a Smith machine. Key pointsVertical jump height in the loaded jump squat can be estimated with acceptable precision from the maximum bar velocity recorded by a linear velocity transducer.The relationship between the point at which bar acceleration is less than -9.81 m·s(-2) and the real take-off is affected by the velocity of movement.Mean propulsive velocity recorded by a linear velocity transducer does not appear to be optimal to monitor ballistic exercise performance.
PRINCIPLES OF AFFINITY-BASED BIOSENSORS
Despite the amount of resources that have been invested by national and international academic, government, and commercial sectors to develop affinity-based biosensor products, little obvious success has been realized through commercialization of these devices for specific applic...
Visualizing Antibody Affinity Maturation in Germinal Centers
Tas, Jeroen M.J.; Mesin, Luka; Pasqual, Giulia; Targ, Sasha; Jacobsen, Johanne T.; Mano, Yasuko M.; Chen, Casie S.; Weill, Jean-Claude; Reynaud, Claude-Agnès; Browne, Edward P.; Meyer-Hermann, Michael; Victora, Gabriel D.
2016-01-01
Antibodies somatically mutate to attain high affinity in germinal centers (GCs). There, competition between B cell clones and among somatic mutants of each clone drives an increase in average affinity across the population. The extent to which higher-affinity cells eliminating competitors restricts clonal diversity is unknown. By combining multiphoton microscopy and sequencing, we show that tens to hundreds of distinct B cell clones seed each GC, and that GCs lose clonal diversity at widely disparate rates. Furthermore, efficient affinity maturation can occur in the absence of homogenizing selection, ensuring that many clones can mature in parallel within the same GC. Our findings have implications for development of vaccines in which antibodies with non-immunodominant specificities must be elicited, as is the case for HIV-1 and influenza. PMID:26912368
Protein purification using PDZ affinity chromatography.
Walkup, Ward G; Kennedy, Mary B
2015-01-01
PDZ domains function in nature as protein-binding domains within scaffold and membrane-associated proteins. They comprise approximately 90 residues and undergo specific, high-affinity interactions with complementary C-terminal peptide sequences, other PDZ domains, and/or phospholipids. We have previously shown that the specific, strong interactions of PDZ domains with their ligands make them well suited for use in affinity chromatography. This unit provides protocols for the PDZ affinity chromatography procedure that are applicable for the purification of proteins that contain PDZ domains or PDZ domain-binding ligands, either naturally or introduced by genetic engineering. We detail the preparation of affinity resins composed of PDZ domains or PDZ domain peptide ligands coupled to solid supports. These resins can be used to purify proteins containing endogenous or genetically introduced PDZ domains or ligands, eluting the proteins with free PDZ domain peptide ligands. PMID:25829303
Designing Chaotic Systems by Piecewise Affine Systems
NASA Astrophysics Data System (ADS)
Wu, Tiantian; Li, Qingdu; Yang, Xiao-Song
Based on mathematical analysis, this paper provides a methodology to ensure the existence of homoclinic orbits in a class of three-dimensional piecewise affine systems. In addition, two chaotic generators are provided to illustrate the effectiveness of the method.
Affinity Electrophoresis Using Ligands Attached To Polymers
NASA Technical Reports Server (NTRS)
Van Alstine, James M.; Snyder, Robert S.; Harris, J. M.; Brooks, D. E.
1990-01-01
In new technique, reduction of electrophoretic mobilities by addition of polyethylene glycol to ligands increases electrophoretic separabilities. In immuno-affinity electrophoresis, modification of ligands extends specificity of electrophoretic separation to particles having surface electric-charge structures otherwise making them electrophoretically inseparable. Modification of antibodies by polyethylene glycol greatly reduces ability to aggregate while enhancing ability to affect electrophoretic mobilities of cells. In hydrophobic-affinity electrophoresis, addition of polyethylene glycol reduces tendency toward aggregation of cells or macromolecules.
Affinity learning with diffusion on tensor product graph.
Yang, Xingwei; Prasad, Lakshman; Latecki, Longin Jan
2013-01-01
In many applications, we are given a finite set of data points sampled from a data manifold and represented as a graph with edge weights determined by pairwise similarities of the samples. Often the pairwise similarities (which are also called affinities) are unreliable due to noise or due to intrinsic difficulties in estimating similarity values of the samples. As observed in several recent approaches, more reliable similarities can be obtained if the original similarities are diffused in the context of other data points, where the context of each point is a set of points most similar to it. Compared to the existing methods, our approach differs in two main aspects. First, instead of diffusing the similarity information on the original graph, we propose to utilize the tensor product graph (TPG) obtained by the tensor product of the original graph with itself. Since TPG takes into account higher order information, it is not a surprise that we obtain more reliable similarities. However, it comes at the price of higher order computational complexity and storage requirement. The key contribution of the proposed approach is that the information propagation on TPG can be computed with the same computational complexity and the same amount of storage as the propagation on the original graph. We prove that a graph diffusion process on TPG is equivalent to a novel iterative algorithm on the original graph, which is guaranteed to converge. After its convergence we obtain new edge weights that can be interpreted as new, learned affinities. We stress that the affinities are learned in an unsupervised setting. We illustrate the benefits of the proposed approach for data manifolds composed of shapes, images, and image patches on two very different tasks of image retrieval and image segmentation. With learned affinities, we achieve the bull's eye retrieval score of 99.99 percent on the MPEG-7 shape dataset, which is much higher than the state-of-the-art algorithms. When the data
Sensitivity to Auditory Velocity Contrast.
Locke, Shannon M; Leung, Johahn; Carlile, Simon
2016-06-13
A natural auditory scene often contains sound moving at varying velocities. Using a velocity contrast paradigm, we compared sensitivity to velocity changes between continuous and discontinuous trajectories. Subjects compared the velocities of two stimulus intervals that moved along a single trajectory, with and without a 1 second inter stimulus interval (ISI). We found thresholds were threefold larger for velocity increases in the instantaneous velocity change condition, as compared to instantaneous velocity decreases or thresholds for the delayed velocity transition condition. This result cannot be explained by the current static "snapshot" model of auditory motion perception and suggest a continuous process where the percept of velocity is influenced by previous history of stimulation.
An affine projection algorithm using grouping selection of input vectors
NASA Astrophysics Data System (ADS)
Shin, JaeWook; Kong, NamWoong; Park, PooGyeon
2011-10-01
This paper present an affine projection algorithm (APA) using grouping selection of input vectors. To improve the performance of conventional APA, the proposed algorithm adjusts the number of the input vectors using two procedures: grouping procedure and selection procedure. In grouping procedure, the some input vectors that have overlapping information for update is grouped using normalized inner product. Then, few input vectors that have enough information for for coefficient update is selected using steady-state mean square error (MSE) in selection procedure. Finally, the filter coefficients update using selected input vectors. The experimental results show that the proposed algorithm has small steady-state estimation errors comparing with the existing algorithms.
NASA Astrophysics Data System (ADS)
Balasubramaniam, K. S.; Keil, S. L.; Smaldone, L. A.
1996-05-01
We investigate the three dimensional structure of solar pores and their surroundings using high spatial and spectral resolution data. We present evidence that surface velocities decrease around pores with a corresponding increase in the line-of-sight (LOS) velocities. LOS velocities in pores increase with the strength of the magnetic field. Surface velocities show convergence toward a weak downflow which appear to trace boundaries resembling meso-granular and super granular flows. The observed magnetic fields in the pores appear near these boundaries. We analyze the vertical velocity structure in pores and show that they generally have downflows decreasing exponentially with height, with a scale height of about 90 km. Evidence is also presented for the expanding nature of flux tubes. Finally we describe a phenomenological model for pores. This work was supported by AFOSR Task 2311G3. LAS was partially supported by the Progetto Nazionale Astrofisica e Fisica Cosmica of MURST and Scambi Internazionali of the Universita degli Studi di Napoli Frederico II. National Solar Observatory, NOAO, is operated for the National Science Foundation by AURA, Inc.
The SPX domain of the yeast low-affinity phosphate transporter Pho90 regulates transport activity
Hürlimann, Hans Caspar; Pinson, Benoît; Stadler-Waibel, Martha; Zeeman, Samuel C; Freimoser, Florian M
2009-01-01
Yeast has two phosphate-uptake systems that complement each other: the high-affinity transporters (Pho84 and Pho89) are active under phosphate starvation, whereas Pho87 and Pho90 are low-affinity transporters that function when phosphate is abundant. Here, we report new regulatory functions of the amino-terminal SPX domain of Pho87 and Pho90. By studying truncated versions of Pho87 and Pho90, we show that the SPX domain limits the phosphate-uptake velocity, suppresses phosphate efflux and affects the regulation of the phosphate signal transduction pathway. Furthermore, split-ubiquitin assays and co-immunoprecipitation suggest that the SPX domain of both Pho90 and Pho87 interacts physically with the regulatory protein Spl2. This work suggests that the SPX domain inhibits low-affinity phosphate transport through a physical interaction with Spl2. PMID:19590579
Mathematical modeling of the low and high affinity arabinose transport systems in Escherichia coli.
Yildirim, Necmettin
2012-04-01
A mathematical model was developed for the low and high affinity arabinose transport systems in E. coli. The model is a system of three ordinary differential equations and takes the dynamics of mRNAs for the araE and araFGH proteins and the internal arabinose into account. Special attention was paid to estimate the model parameters from the literature. Our analysis and simulations suggest that the high affinity transport system helps the low affinity transport system to respond to high concentration of extracellular arabinose faster, whereas the high affinity transport system responds to a small amount of extracellular arabinose. Steady state analysis of the model also predicts that there is a regime for the extracellular concentration of arabinose where the arabinose system can show bistable behavior.
Quantitative velocity modulation spectroscopy
NASA Astrophysics Data System (ADS)
Hodges, James N.; McCall, Benjamin J.
2016-05-01
Velocity Modulation Spectroscopy (VMS) is arguably the most important development in the 20th century for spectroscopic study of molecular ions. For decades, interpretation of VMS lineshapes has presented challenges due to the intrinsic covariance of fit parameters including velocity modulation amplitude, linewidth, and intensity. This limitation has stifled the growth of this technique into the quantitative realm. In this work, we show that subtle changes in the lineshape can be used to help address this complexity. This allows for determination of the linewidth, intensity relative to other transitions, velocity modulation amplitude, and electric field strength in the positive column of a glow discharge. Additionally, we explain the large homogeneous component of the linewidth that has been previously described. Using this component, the ion mobility can be determined.
Best approximation of functions in L{sub p} by polynomials on affine system
Terekhin, Pavel A
2011-02-28
Estimates of the best L{sub p}-approximation of functions by polynomials in an affine system (system of dilations and translations), which are similar to well-known estimates due to Ul'yanov and Golubov for approximations in the Haar system, are obtained. An analogue of A.F. Timan and M.F. Timan's inequality is shown to hold under certain conditions on the generating function of the affine system; this analogue fails for the Haar system for 1
Zheng, Xiwei; Podariu, Maria; Matsuda, Ryan; Hage, David S
2016-01-01
Ultrafast affinity extraction and a two-dimensional high performance affinity chromatographic system were used to measure the free fractions for various drugs in serum and at typical therapeutic concentrations. Pooled samples of normal serum or serum from diabetic patients were utilized in this work. Several drug models (i.e., quinidine, diazepam, gliclazide, tolbutamide, and acetohexamide) were examined that represented a relatively wide range of therapeutic concentrations and affinities for human serum albumin (HSA). The two-dimensional system consisted of an HSA microcolumn for the extraction of a free drug fraction, followed by a larger HSA analytical column for the further separation and measurement of this fraction. Factors that were optimized in this method included the flow rates, column sizes, and column switching times that were employed. The final extraction times used for isolating the free drug fractions were 333-665 ms or less. The dissociation rate constants for several of the drugs with soluble HSA were measured during system optimization, giving results that agreed with reference values. In the final system, free drug fractions in the range of 0.7-9.5% were measured and gave good agreement with values that were determined by ultrafiltration. Association equilibrium constants or global affinities were also estimated by this approach for the drugs with soluble HSA. The results for the two-dimensional system were obtained in 5-10 min or less and required only 1-5 μL of serum per injection. The same approach could be adapted for work with other drugs and proteins in clinical samples or for biomedical research. PMID:26462924
Cirrus Crystal Terminal Velocities.
NASA Astrophysics Data System (ADS)
Heymsfield, Andrew J.; Iaquinta, Jean
2000-04-01
Cirrus crystal terminal velocities are of primary importance in determining the rate of transport of condensate from upper- to middle-tropospheric levels and profoundly influence the earth's radiation balance through their effect on the rate of buildup or decay of cirrus clouds. In this study, laboratory and field-based cirrus crystal drag coefficient data, as well as analytical descriptions of cirrus crystal shapes, are used to derive more physically based expressions for the velocities of cirrus crystals than have been available in the past.Polycrystals-often bullet rosettes-are shown to be the dominant crystal types in synoptically generated cirrus, with columns present in varying but relatively large percentages, depending on the cloud. The two critical parameters needed to calculate terminal velocity are the drag coefficient and the ratio of mass to cross-sectional area normal to their fall direction. Using measurements and calculations, it is shown that drag coefficients from theory and laboratory studies are applicable to crystals of the types found in cirrus. The ratio of the mass to area, which is shown to be relatively independent of the number of bullets in the rosette, is derived from an analytic model that represents bullet rosettes containing one to eight bullets in 19 primary geometric configurations. The ratio is also derived for columns. Using this information, a general set of equations is developed to calculate the terminal velocities and masses in terms of the aspect ratio (width divided by length), ice density, and rosette maximum dimension. Simple expressions for terminal velocity and mass as a function of bullet rosette maximum dimension are developed by incorporating new information on bullet aspect ratios.The general terminal velocity and mass relations are then applied to a case from the First International Satellite Cloud Climatology Project (ISCCP) Research Experiment (FIRE) 2, when size spectra from a balloon-borne ice crystal
Advanced PDV velocity extraction
NASA Astrophysics Data System (ADS)
Dolan, Daniel; Ao, Tommy; Furnish, Michael
2015-06-01
While PDV has become a standard diagnostic, reliable velocity extraction remains challenging. Measurements with multiple real/apparent velocities are intrinsically difficult to analyze, and overlapping frequency components invalidate standard extraction methods. This presentation describes an advanced analysis technique where overlapping frequency components are resolved in the complex Fourier spectrum. Practical matters--multiple region of interest selection, component intersection, and shock transitions--will also be discussed. Sandia National Laboratories is a multi-program laboratory operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85.
Velocity pump reaction turbine
House, P.A.
An expanding hydraulic/two-phase velocity pump reaction turbine including a dual concentric rotor configuration with an inter-rotor annular flow channel in which the inner rotor is mechanically driven by the outer rotor. In another embodiment, the inner rotor is immobilized and provided with gas recovery ports on its outer surface by means of which gas in solution may be recovered. This velocity pump reaction turbine configuration is capable of potential energy conversion efficiencies of up to 70%, and is particularly suited for geothermal applications.
Velocity pump reaction turbine
House, Palmer A.
1984-01-01
An expanding hydraulic/two-phase velocity pump reaction turbine including a dual concentric rotor configuration with an inter-rotor annular flow channel in which the inner rotor is mechanically driven by the outer rotor. In another embodiment, the inner rotor is immobilized and provided with gas recovery ports on its outer surface by means of which gas in solution may be recovered. This velocity pump reaction turbine configuration is capable of potential energy conversion efficiencies of up to 70%, and is particularly suited for geothermal applications.
Velocity pump reaction turbine
House, Palmer A.
1982-01-01
An expanding hydraulic/two-phase velocity pump reaction turbine including a dual concentric rotor configuration with an inter-rotor annular flow channel in which the inner rotor is mechanically driven by the outer rotor. In another embodiment, the inner rotor is immobilized and provided with gas recovery ports on its outer surface by means of which gas in solution may be recovered. This velocity pump reaction turbine configuration is capable of potential energy conversion efficiencies of up to 70%, and is particularly suited for geothermal applications.
NASA Astrophysics Data System (ADS)
Schimd, C.; Courtois, H.; Koda, J.
2015-12-01
A huge velocity survey based on the Maunakea Spectroscopic Explorer facility (MSE) is proposed, aiming at investigating the structure and dynamics of the cosmic web over 3π steradians up to ˜1 Gpc and at unprecedented spatial resolution, its relationship with the galaxy formation process, and the bias between galaxies and dark matter during the last three billions years. The cross-correlation of velocity and density fields will further allow the probe any deviation from General Relativity by measuring the the linear-growth rate of cosmic structures at precision competitive with high-redshift spectroscopic redshift surveys.
The velocity snake: Deformable contour for tracking in spatio-velocity space
Peterfreund, N.
1997-06-01
The author presents a new active contour model for boundary tracking and position prediction of nonrigid objects, which results from applying a velocity control to the class of elastodynamical contour models, known as snakes. The proposed control term minimizes an energy dissipation function which measures the difference between the contour velocity and the apparent velocity of the image. Treating the image video-sequence as continuous measurements along time, it is shown that the proposed control results in an unbiased tracking. This is in contrast to the original snake model which is proven to be biased due to the image (object) velocity, thus resulting in high sensitivity to image clutter. The motion estimation further allows for position prediction of nonrigid boundaries. Based on the proposed control approach, the author proposes a new class of real time tracking contours, varying from models with batch-mode control estimation to models with real time adaptive controllers.
Classification of neocortical interneurons using affinity propagation
Santana, Roberto; McGarry, Laura M.; Bielza, Concha; Larrañaga, Pedro; Yuste, Rafael
2013-01-01
In spite of over a century of research on cortical circuits, it is still unknown how many classes of cortical neurons exist. In fact, neuronal classification is a difficult problem because it is unclear how to designate a neuronal cell class and what are the best characteristics to define them. Recently, unsupervised classifications using cluster analysis based on morphological, physiological, or molecular characteristics, have provided quantitative and unbiased identification of distinct neuronal subtypes, when applied to selected datasets. However, better and more robust classification methods are needed for increasingly complex and larger datasets. Here, we explored the use of affinity propagation, a recently developed unsupervised classification algorithm imported from machine learning, which gives a representative example or exemplar for each cluster. As a case study, we applied affinity propagation to a test dataset of 337 interneurons belonging to four subtypes, previously identified based on morphological and physiological characteristics. We found that affinity propagation correctly classified most of the neurons in a blind, non-supervised manner. Affinity propagation outperformed Ward's method, a current standard clustering approach, in classifying the neurons into 4 subtypes. Affinity propagation could therefore be used in future studies to validly classify neurons, as a first step to help reverse engineer neural circuits. PMID:24348339
BC(50): a generalized, unifying affinity descriptor.
Vacca, Alberto; Francesconi, Oscar; Roelens, Stefano
2012-12-01
Assessing binding affinities is an unavoidable step that we come across any time interactions between binding species are investigated. A quantitative evaluation of binding affinities relies on the determination of binding constants but, whilst the binding constant fully defines the affinity of a reagent for a ligand when only one complex species is formed, the same is not true when the interacting partners form more than one complex of different stoichiometry, because all complexes contribute to the overall binding affinity. Unfortunately, this situation is the rule rather than the exception in chemical systems, but a generally accepted solution for this issue has not yet been settled. In this Personal Account, we describe the evolution, from the initial idea to a fully developed stage, of a binding descriptor that has been developed with the aim of filling this gap, thereby providing scientists in all fields of chemistry with a unifying tool for the assessment of binding affinities based on the knowledge of the binding constants in systems that involve any number of complex species.
Classification of neocortical interneurons using affinity propagation.
Santana, Roberto; McGarry, Laura M; Bielza, Concha; Larrañaga, Pedro; Yuste, Rafael
2013-01-01
In spite of over a century of research on cortical circuits, it is still unknown how many classes of cortical neurons exist. In fact, neuronal classification is a difficult problem because it is unclear how to designate a neuronal cell class and what are the best characteristics to define them. Recently, unsupervised classifications using cluster analysis based on morphological, physiological, or molecular characteristics, have provided quantitative and unbiased identification of distinct neuronal subtypes, when applied to selected datasets. However, better and more robust classification methods are needed for increasingly complex and larger datasets. Here, we explored the use of affinity propagation, a recently developed unsupervised classification algorithm imported from machine learning, which gives a representative example or exemplar for each cluster. As a case study, we applied affinity propagation to a test dataset of 337 interneurons belonging to four subtypes, previously identified based on morphological and physiological characteristics. We found that affinity propagation correctly classified most of the neurons in a blind, non-supervised manner. Affinity propagation outperformed Ward's method, a current standard clustering approach, in classifying the neurons into 4 subtypes. Affinity propagation could therefore be used in future studies to validly classify neurons, as a first step to help reverse engineer neural circuits.
Classification of neocortical interneurons using affinity propagation.
Santana, Roberto; McGarry, Laura M; Bielza, Concha; Larrañaga, Pedro; Yuste, Rafael
2013-01-01
In spite of over a century of research on cortical circuits, it is still unknown how many classes of cortical neurons exist. In fact, neuronal classification is a difficult problem because it is unclear how to designate a neuronal cell class and what are the best characteristics to define them. Recently, unsupervised classifications using cluster analysis based on morphological, physiological, or molecular characteristics, have provided quantitative and unbiased identification of distinct neuronal subtypes, when applied to selected datasets. However, better and more robust classification methods are needed for increasingly complex and larger datasets. Here, we explored the use of affinity propagation, a recently developed unsupervised classification algorithm imported from machine learning, which gives a representative example or exemplar for each cluster. As a case study, we applied affinity propagation to a test dataset of 337 interneurons belonging to four subtypes, previously identified based on morphological and physiological characteristics. We found that affinity propagation correctly classified most of the neurons in a blind, non-supervised manner. Affinity propagation outperformed Ward's method, a current standard clustering approach, in classifying the neurons into 4 subtypes. Affinity propagation could therefore be used in future studies to validly classify neurons, as a first step to help reverse engineer neural circuits. PMID:24348339
Affinity purification of aprotinin from bovine lung.
Xin, Yu; Liu, Lanhua; Chen, Beizhan; Zhang, Ling; Tong, Yanjun
2015-05-01
An affinity protocol for the purification of aprotinin from bovine lung was developed. To simulate the structure of sucrose octasulfate, a natural specific probe for aprotinin, the affinity ligand was composed of an acidic head and a hydrophobic stick, and was then linked with Sepharose. The sorbent was then subjected to adsorption analysis with pure aprotinin. The purification process consisted of one step of affinity chromatography and another step of ultrafiltration. Then purified aprotinin was subjected to sodium dodecyl sulfate polyacrylamide gel electrophoresis, trypsin inhibitor activity, gel-filtration, and thin-layer chromatography analysis. As calculated, the theoretical maximum adsorption (Qmax ) of the affinity sorbent was 25,476.0 ± 184.8 kallikrein inactivator unit/g wet gel; the dissociation constant of the complex "immobilized ligand-aprotinin" (Kd ) was 4.6 ± 0.1 kallikrein inactivator unit/mL. After the affinity separation of bovine lung aprotinin, reducing sodium dodecyl sulfate polyacrylamide gel electrophoresis analysis and gel-filtration chromatography revealed that the protein was a single polypeptide, and the purities were ∼ 97 and 100%, respectively; the purified peptide was also confirmed with aprotinin standard by gel-filtration chromatography and thin-layer chromatography. After the whole purification process, protein, and bioactivity recoveries were 2.2 and 92.6%, respectively; and the specific activity was up to 15,907.1 ± 10.2 kallikrein inactivator unit/mg. PMID:25677462
Identity, Affinity, Reality: Making the Case for Affinity Groups in Elementary School
ERIC Educational Resources Information Center
Parsons, Julie; Ridley, Kimberly
2012-01-01
Affinity groups are places where students build connections and process "ouch" moments from their classes. Children talk about the isolation they sometimes feel. The relationships students gain through race-based affinity groups enable them to feel less alone with their emotions and help them build a stronger sense of self. At the same time,…
Stepparents' Affinity-Seeking and Affinity-Maintaining Strategies with Stepchildren.
ERIC Educational Resources Information Center
Ganong, Lawrence; Coleman, Marilyn; Fine, Mark; Martin, Patricia
1999-01-01
Examines the strategies that stepparents use to develop and maintain affinity with stepchildren and the effects that these strategies have on the development of stepparent-stepchildren relationships. Thirty-one affinity-seeking strategies are identified. Results show that dyadic activities worked best, but it is important that stepchildren…
ERIC Educational Resources Information Center
Brand, Neal; Quintanilla, John A.
2013-01-01
Using a simultaneously falling softball as a stopwatch, the terminal velocity of a whiffle ball can be obtained to surprisingly high accuracy with only common household equipment. This classroom activity engages students in an apparently daunting task that nevertheless is tractable, using a simple model and mathematical techniques at their…
Affinity chromatography of bacterial lactate dehydrogenases.
Kelly, N; Delaney, M; O'Carra, P
1978-01-01
The affinity system used was the immobilized oxamate derivative previously used to purify mammalian lactate dehydrogenases. The bacterial dehydrogenases specific for the L-stereoisomer of lactate behaved in the same way as the mammalian enzymes, binding strongly in the presence of NADH. The D-lactate-specific enzymes, however, did not show any biospecific affinity for this gel. The L-specific enzymes could be purified to homogeneity in one affinity-chromatographic step. The D-specific enzymes could be efficiently separated from the L-specific ones and could then be further purified on an immobilized NAD derivative. The mechanism of activation of the lactate dehydrogenase from Streptococcus faecalis by fructose 1,6-bisphosphate was investigated by using the immobilized oxamate gel. PMID:666726
Affinity chromatography of bacterial lactate dehydrogenases.
Kelly, N; Delaney, M; O'Carra, P
1978-06-01
The affinity system used was the immobilized oxamate derivative previously used to purify mammalian lactate dehydrogenases. The bacterial dehydrogenases specific for the L-stereoisomer of lactate behaved in the same way as the mammalian enzymes, binding strongly in the presence of NADH. The D-lactate-specific enzymes, however, did not show any biospecific affinity for this gel. The L-specific enzymes could be purified to homogeneity in one affinity-chromatographic step. The D-specific enzymes could be efficiently separated from the L-specific ones and could then be further purified on an immobilized NAD derivative. The mechanism of activation of the lactate dehydrogenase from Streptococcus faecalis by fructose 1,6-bisphosphate was investigated by using the immobilized oxamate gel. PMID:666726
A velocity dependent effective angle method for calibration of X-probes at low velocities
NASA Astrophysics Data System (ADS)
Bakken, Ole Martin; Krogstad, Per-Åge
A velocity dependent effective angle (VDEA) method for the calibration of yaw response of hot-wire X-probes at low flow velocities (0.5-6 m/s) is presented. Comparisons with a full velocity vs. yaw-angle method (Österlund 1999) in a smooth wall channel flow indicate that there is only moderate advantage in using the latter method, which is considerably more laborious. Comparisons with direct numerical simulations (DNS) (Moser et al. 1999) and the more common fixed effective angle method (FEA) show that the VDEA method significantly improves estimates of Reynolds stresses compared to the FEA method.
Influence of affinity on antibody determination in microtiter ELISA systems
Peterman, J.H.; Voss, E.W. Jr.; Butler, J.E.
1986-03-01
Theoretically, all immunoassays are affinity (Ka) dependent when the product of the antibody (Ab) Ka and the free epitope concentration is less than 10. Thus, the degree of dependence on Ka depends on the concentration of available antigen in the system. The authors examined the binding of /sup 125/I-anti-fluorescein (a-FLU) monoclonal antibodies of different affinities to FLU-gelatin adsorbed on Immunlon 2 microtiter plates. Data obtained were in general agreement with our theoretical predictions; the percent of /sup 125/I-a-FLU which bound correlated with Ka, as did the shape of the titration curves. Measurement of 5 a-FLU monoclonals by the ELISA showed that the determination of Ab concentrations depends on the FLU-gelatin concentration, epitope density, and on the relationship between the Kas of test samples and the reference standard Ab preparation. Thus the ELISA is Ka dependent and should not be used routinely to estimate the absolute amount to Ab in unknown samples. However, the Ka dependency of the ELISA might provide a convenient assay for the estimation of the relative functional Ka (rfKa) of antibody preparations.
European and international collaboration in affinity proteomics.
Stoevesandt, Oda; Taussig, Michael J
2012-06-15
In affinity proteomics, specific protein-binding molecules (a.k.a. binders), principally antibodies, are applied as reagents in proteome analysis. In recent years, advances in binder technologies have created the potential for an unprecedented view on protein expression and distribution patterns in plasma, cells and tissues and increasingly on protein function. Particular strengths of affinity proteomics methods include detecting proteins in their natural environments of cell or tissue, high sensitivity and selectivity for detection of low abundance proteins and exploiting binding actions such as functional interference in living cells. To maximise the use and impact of affinity reagents, it will be essential to create comprehensive, standardised binder collections. With this in mind, the EU FP7 programme AFFINOMICS (http://www.affinomics.org), together with the preceding EU programmes ProteomeBinders and AffinityProteome, aims to extend affinity proteomics research by generating a large-scale resource of validated protein-binding molecules for characterisation of the human proteome. Activity is directed at producing binders to about 1000 protein targets, primarily in signal transduction and cancer, by establishing a high throughput, coordinated production pipeline. An important aspect of AFFINOMICS is the development of highly efficient recombinant selection methods, based on phage, cell and ribosome display, capable of producing high quality binders at greater throughput and lower cost than hitherto. The programme also involves development of innovative and sensitive technologies for specific detection of target proteins and their interactions, and deployment of binders in proteomics studies of clinical relevance. The need for such binder generation programmes is now recognised internationally, with parallel initiatives in the USA for cancer (NCI) and transcription factors (NIH) and within the Human Proteome Organisation (HUPO). The papers in this volume of New
Displacement phenomena in lectin affinity chromatography.
Cho, Wonryeon
2015-10-01
The work described here examines displacement phenomena that play a role in lectin affinity chromatography and their potential to impact reproducibility. This was achieved using Lycopersicon esculentum lectin (LEL), a lectin widely used in monitoring cancer. Four small identical LEL columns were coupled in series to form a single affinity chromatography system with the last in the series connected to an absorbance detector. The serial affinity column set (SACS) was then loaded with human plasma proteins. At the completion of loading, the column set was disassembled, the four columns were eluted individually, the captured proteins were trypsin digested, the peptides were deglycosylated with PNGase F, and the parent proteins were identified through mass spectral analyses. Significantly different sets of glycoproteins were selected by each column, some proteins appearing to be exclusively bound to the first column while others were bound further along in the series. Clearly, sample displacement chromatography (SDC) occurs. Glycoproteins were bound at different places in the column train, identifying the presence of glycoforms with different affinity on a single glycoprotein. It is not possible to see these phenomena in the single column mode of chromatography. Moreover, low abundance proteins were enriched, which facilitates detection. The great advantage of this method is that it differentiates between glycoproteins on the basis of their binding affinity. Displacement phenomena are concluded to be a significant component of the separation mechanism in heavily loaded lectin affinity chromatography columns. This further suggests that care must be exercised in sample loading of lectin columns to prevent analyte displacement with nonretained proteins. PMID:26348026
The dynamics of metric-affine gravity
Vitagliano, Vincenzo; Sotiriou, Thomas P.; Liberati, Stefano
2011-05-15
Highlights: > The role and the dynamics of the connection in metric-affine theories is explored. > The most general second order action does not lead to a dynamical connection. > Including higher order invariants excites new degrees of freedom in the connection. > f(R) actions are also discussed and shown to be a non- representative class. - Abstract: Metric-affine theories of gravity provide an interesting alternative to general relativity: in such an approach, the metric and the affine (not necessarily symmetric) connection are independent quantities. Furthermore, the action should include covariant derivatives of the matter fields, with the covariant derivative naturally defined using the independent connection. As a result, in metric-affine theories a direct coupling involving matter and connection is also present. The role and the dynamics of the connection in such theories is explored. We employ power counting in order to construct the action and search for the minimal requirements it should satisfy for the connection to be dynamical. We find that for the most general action containing lower order invariants of the curvature and the torsion the independent connection does not carry any dynamics. It actually reduces to the role of an auxiliary field and can be completely eliminated algebraically in favour of the metric and the matter field, introducing extra interactions with respect to general relativity. However, we also show that including higher order terms in the action radically changes this picture and excites new degrees of freedom in the connection, making it (or parts of it) dynamical. Constructing actions that constitute exceptions to this rule requires significant fine tuned and/or extra a priori constraints on the connection. We also consider f(R) actions as a particular example in order to show that they constitute a distinct class of metric-affine theories with special properties, and as such they cannot be used as representative toy theories to
Affine Invariant Character Recognition by Progressive Removing
NASA Astrophysics Data System (ADS)
Iwamura, Masakazu; Horimatsu, Akira; Niwa, Ryo; Kise, Koichi; Uchida, Seiichi; Omachi, Shinichiro
Recognizing characters in scene images suffering from perspective distortion is a challenge. Although there are some methods to overcome this difficulty, they are time-consuming. In this paper, we propose a set of affine invariant features and a new recognition scheme called “progressive removing” that can help reduce the processing time. Progressive removing gradually removes less feasible categories and skew angles by using multiple classifiers. We observed that progressive removing and the use of the affine invariant features reduced the processing time by about 60% in comparison to a trivial one without decreasing the recognition rate.
Negative Electron Affinity Mechanism for Diamond Surfaces
NASA Technical Reports Server (NTRS)
Krainsky, I. L.; Asnin, V. M.
1998-01-01
The energy distribution of the secondary electrons for chemical vacuum deposited diamond films with Negative Electron Affinity (NEA) was investigated. It was found that while for completely hydrogenated diamond surfaces the negative electron affinity peak in the energy spectrum of the secondary electrons is present for any energy of the primary electrons, for partially hydrogenated diamond surfaces there is a critical energy above which the peak is present in the spectrum. This critical energy increases sharply when hydrogen coverage of the diamond surface diminishes. This effect was explained by the change of the NEA from the true type for the completely hydrogenated surface to the effective type for the partially hydrogenated surfaces.
Adsorption affinity of anions on metal oxyhydroxides
NASA Astrophysics Data System (ADS)
Pechenyuk, S. I.; Semushina, Yu. P.; Kuz'mich, L. F.
2013-03-01
The dependences of anion (phosphate, carbonate, sulfate, chromate, oxalate, tartrate, and citrate) adsorption affinity anions from geometric characteristics, acid-base properties, and complex forming ability are generalized. It is shown that adsorption depends on the nature of both the anions and the ionic medium and adsorbent. It is established that anions are generally grouped into the following series of adsorption affinity reduction: PO{4/3-}, CO{3/2-} > C2O{4/2-}, C(OH)(CH2)2(COO){3/3-}, (CHOH)2(COO){2/2-} > CrO{4/2-} ≫ SO{4/2-}.
Simulating photospheric Doppler velocity fields
NASA Technical Reports Server (NTRS)
Hathaway, David H.
1988-01-01
A method is described for constructing artificial data that realistically simulate photospheric velocity fields. The velocity fields include rotation, differential rotation, meridional circulation, giant cell convection, supergranulation, convective limb shift, p-mode oscillations, and observer motion. Data constructed by this method can be used for testing algorithms designed to extract and analyze these velocity fields in real Doppler velocity data.
Ensemble estimators for multivariate entropy estimation
Sricharan, Kumar; Wei, Dennis; Hero, Alfred O.
2015-01-01
The problem of estimation of density functionals like entropy and mutual information has received much attention in the statistics and information theory communities. A large class of estimators of functionals of the probability density suffer from the curse of dimensionality, wherein the mean squared error (MSE) decays increasingly slowly as a function of the sample size T as the dimension d of the samples increases. In particular, the rate is often glacially slow of order O(T−γ/d), where γ > 0 is a rate parameter. Examples of such estimators include kernel density estimators, k-nearest neighbor (k-NN) density estimators, k-NN entropy estimators, intrinsic dimension estimators and other examples. In this paper, we propose a weighted affine combination of an ensemble of such estimators, where optimal weights can be chosen such that the weighted estimator converges at a much faster dimension invariant rate of O(T−1). Furthermore, we show that these optimal weights can be determined by solving a convex optimization problem which can be performed offline and does not require training data. We illustrate the superior performance of our weighted estimator for two important applications: (i) estimating the Panter-Dite distortion-rate factor and (ii) estimating the Shannon entropy for testing the probability distribution of a random sample. PMID:25897177
Microseismic Velocity Imaging of the Fracturing Zone
NASA Astrophysics Data System (ADS)
Zhang, H.; Chen, Y.
2015-12-01
Hydraulic fracturing of low permeability reservoirs can induce microseismic events during fracture development. For this reason, microseismic monitoring using sensors on surface or in borehole have been widely used to delineate fracture spatial distribution and to understand fracturing mechanisms. It is often the case that the stimulated reservoir volume (SRV) is determined solely based on microseismic locations. However, it is known that for some fracture development stage, long period long duration events, instead of microseismic events may be associated. In addition, because microseismic events are essentially weak and there exist different sources of noise during monitoring, some microseismic events could not be detected and thus located. Therefore the estimation of the SRV is biased if it is solely determined by microseismic locations. With the existence of fluids and fractures, the seismic velocity of reservoir layers will be decreased. Based on this fact, we have developed a near real time seismic velocity tomography method to characterize velocity changes associated with fracturing process. The method is based on double-difference seismic tomography algorithm to image the fracturing zone where microseismic events occur by using differential arrival times from microseismic event pairs. To take into account varying data distribution for different fracking stages, the method solves the velocity model in the wavelet domain so that different scales of model features can be obtained according to different data distribution. We have applied this real time tomography method to both acoustic emission data from lab experiment and microseismic data from a downhole microseismic monitoring project for shale gas hydraulic fracturing treatment. The tomography results from lab data clearly show the velocity changes associated with different rock fracturing stages. For the field data application, it shows that microseismic events are located in low velocity anomalies. By
Spall velocity measurements from laboratory impact craters
NASA Technical Reports Server (NTRS)
Polanskey, Carol A.; Ahrens, Thomas J.
1986-01-01
Spall velocities were measured for a series of impacts into San Marcos gabbro. Impact velocities ranged from 1 to 6.5 km/sec. Projectiles varied in material and size with a maximum mass of 4g for a lead bullet to a minimum of 0.04 g for an aluminum sphere. The spall velocities were calculated both from measurements taken from films of the events and from estimates based on range measurements of the spall fragments. The maximum spall velocity observed was 27 m/sec, or 0.5 percent of the impact velocity. The measured spall velocities were within the range predicted by the Melosh (1984) spallation model for the given experimental parameters. The compatability between the Melosh model for large planetary impacts and the results of these small scale experiments is considered in detail. The targets were also bisected to observe the internal fractures. A series of fractures were observed whose location coincided with the boundary of the theoretical near surface zone predicted by Melosh. Above this boundary the target material should receive reduced levels of compressive stress as compared to the more highly shocked region below.
Measurements of Shaped Charge Jet Velocity
NASA Astrophysics Data System (ADS)
Huang, Hongfa
2013-06-01
Penetration depth is an important requirement in oil/gas well perforating jobs. The depth determines how far the wellbore can directly communicate with reservoir fluids. Deep perforation charges are widely used in oilfield industry and most of those are powder metal liner charge for no carrot-like slug left as solid liner does. Comprehensive measurements for the powder metal liner shaped charge jet characteristics, namely, the jet density and velocity, are needed to predict the shaped charge performance and to plan the perforating job. This paper focuses on an experimental work of jet velocity measurements. A medium size of powder metal liner charges (27 grams HMX) is used in the tests. The powder jet shoots through a stack of limestone blocks with shorting switch set in between. Half inch air-gap between two blocks is design to provide space for jet traveling in air to record free fly velocity, meanwhile the jet penetration velocity in the limestone is measured. Aluminum foil switches are used to record the jet Time of Arrival (TOA). The charged switch shorted by the metal jet when it arrives. The shorting signal is recorded. The two velocities can be used to estimate the jet penetration effectiveness. A series of TOA tests show that jet velocity along its length linearly decreases from jet tip to tail until the stagnation points referring to which jet material moves in opposite direction.
Derivation of vertical air velocity from conventional Radiosonde ascents
NASA Astrophysics Data System (ADS)
Manguttathil Gopalakrishnan, Manoj; Mohanakumar, Kesavapillai; Samson, Titu; Kottayil, Ajil; Varadarajan, Rakesh; Rebello, Rejoy
2016-07-01
In this work, we devise a method to estimate air vertical velocity from ascending radiosondes similar to that described in published results, but with certain differences in deriving the balloon parameters and the drag coefficient, while not considering explicitly the heat exchange between the balloon and the environment. We basically decompose the observed balloon ascent rate into vertical velocity in still air due to buoyancy force and that due to vertical air motion. The first part is computed from basic hydrodynamical principles and the vertical velocity is derived as the difference between observed ascent rate and the estimated still air vertical velocity. The derived values agree reasonably well (r=0.66) with vertical velocities observed with a collocated wind profiler radar, and the sources of uncertainties are discussed. Since vertical velocity is a difficult quantity to measure directly without expensive methods, derivation of the same from the conventional radiosonde ascents could be of great importance to the meteorological communities.
Seismic velocity structure of the lunar mantle
NASA Astrophysics Data System (ADS)
Nakamura, Y.
1983-01-01
The recently completed set of seismic arrival times from the Apollo lunar seismic network are inverted to estimate the average seismic velocities in three sections of the lunar mantle: two for the upper mantle and one for the middle mantle. The method used is a variation of the linearized least squares inversion where the inversion is accomplished in steps. The estimated average velocities in the upper mantle decrease from Vp = 7.74 km/sec and Vs = 4.49 km/sec in the section above 270-km depth to Vp = 7.46 km/sec and Vs = 4.25 km/sec in the section between 270- and 500-km depth, confirming the earlier finding of negative gradients based on seismic amplitude variations. The average velocities in the middle mantle between the depths of 500 km and 1000 km of Vp = 8.26 km/sec and Vs = 4.65 km/sec are significantly higher than those in the upper mantle, contradicting earlier estimates based on more limited data. The higher velocities may suggest initial melting of the moon down to at least 1000-km depth.
Evolution of planetesimal velocities
NASA Technical Reports Server (NTRS)
Stewart, Glen R.; Wetherill, George W.
1987-01-01
A self-consistent set of equations for the velocity evolution of a general planetesimal population is presented. The equations are given in a form convenient for calculations of the early stages of planetary accumulation when it is necessary to model the planetesimal swarm by methods of gas dynamics, rather than follow the orbital evolution of individual bodies. Steady state velocities of a simple planetesimal population consisting of two different sizes of bodies are calculated. Dynamical friction is found to be an important mechanism for transferring kinetic energy from the larger planetesimals to the smaller ones. When the small planetesimals are relatively abundant, gas drag and inelastic collisions among the smaller bodies are of comparable importance for dissipating energy from the population.
Evolution of planetesimal velocities
NASA Astrophysics Data System (ADS)
Stewart, G. R.; Wetherill, G. W.
1988-06-01
A self-consistent set of equations for the velocity evolution of a general planetesimal population is presented. Dynamical friction is found to be an important mechanism for transferring kinetic energy from the larger planetesimals to the smaller ones, providing an energy source for the small planetesimals that is comparable to that provided by the viscous stirring process. When small planetesimals are relatively abundant, gas drag and inelastic collisions among the smaller bodies are of comparable importance for dissipating energy from the population.
Acceleration and Velocity Sensing from Measured Strain
NASA Technical Reports Server (NTRS)
Pak, Chan-Gi; Truax, Roger
2016-01-01
A simple approach for computing acceleration and velocity of a structure from the strain is proposed in this study. First, deflection and slope of the structure are computed from the strain using a two-step theory. Frequencies of the structure are computed from the time histories of strain using a parameter estimation technique together with an Autoregressive Moving Average model. From deflection, slope, and frequencies of the structure, acceleration and velocity of the structure can be obtained using the proposed approach. shape sensing, fiber optic strain sensor, system equivalent reduction and expansion process.
Enhanced reduction of velocity data obtained during CETA flight experiment
NASA Technical Reports Server (NTRS)
Finley, Tom D.; Wong, Douglas T.; Tripp, John S.
1993-01-01
A newly developed technique for enhanced data reduction provides an improved procedure that allows least squares minimization to become possible between data sets with an unequal number of data points. This technique was applied in the Crew and Equipment Translation Aid (CETA) experiment on the STS-37 Shuttle flight in April 1991 to obtain the velocity profile from the acceleration data. The new technique uses a least-squares method to estimate the initial conditions and calibration constants. These initial conditions are estimated by least-squares fitting the displacements indicated by the Hall-effect sensor data to the corresponding displacements obtained from integrating the acceleration data. The velocity and displacement profiles can then be recalculated from the corresponding acceleration data using the estimated parameters. This technique, which enables instantaneous velocities to be obtained from the test data instead of only average velocities at varying discrete times, offers more detailed velocity information, particularly during periods of large acceleration or deceleration.
Modern affinity reagents: Recombinant antibodies and aptamers.
Groff, Katherine; Brown, Jeffrey; Clippinger, Amy J
2015-12-01
Affinity reagents are essential tools in both basic and applied research; however, there is a growing concern about the reproducibility of animal-derived monoclonal antibodies. The need for higher quality affinity reagents has prompted the development of methods that provide scientific, economic, and time-saving advantages and do not require the use of animals. This review describes two types of affinity reagents, recombinant antibodies and aptamers, which are non-animal technologies that can replace the use of animal-derived monoclonal antibodies. Recombinant antibodies are protein-based reagents, while aptamers are nucleic-acid-based. In light of the scientific advantages of these technologies, this review also discusses ways to gain momentum in the use of modern affinity reagents, including an update to the 1999 National Academy of Sciences monoclonal antibody production report and federal incentives for recombinant antibody and aptamer efforts. In the long-term, these efforts have the potential to improve the overall quality and decrease the cost of scientific research.
Two bradykinin binding sites with picomolar affinities
Manning, D.C.; Vavrek, R.; Stewart, J.M.; Snyder, S.H.
1986-05-01
Bradykinin (BK) and related peptides exert a wide range of effects on several organ systems. We have attempted to sort out these effects by studying the binding interaction of (/sup 3/H)BK at the membrane level with in vitro receptor binding techniques. High specific activity (/sup 3/H)BK and an enzyme inhibitor cocktail has enabled us to label two BK binding sites with different affinity and peptide specificity in several guinea-pig tissues. In the guinea-pig ileum the high-affinity site has an equilibrium dissociation constant (Kd) for (/sup 3/H)BK of 13 pM and a maximal number of binding sites of 8.3 pmol/g of tissue wet weight. The low-affinity guinea-pig ileum site displays a Kd of 910 pM, a maximum number of binding sites of 14 pmol/g of tissue wet weight and shows a greater selectivity for BK analogs over Lysyl-BK analogs. Two similar sites can also be discriminated in kidney and heart. The potencies of a series of BK analogs at the high-affinity guinea-pig ileum site correlate well with their potencies in contracting ileal smooth muscle. The binding of (/sup 3/H)BK in the guinea-pig ileum is inhibited by physiological concentrations of monovalent and divalent cations.
Dai, Lu; Li, Weikang; Sun, Fei; Li, Baizhi; Li, Hongrui; Zhang, Hongxing; Zheng, Qingchuan; Liang, Chongyang
2016-09-01
Designing affinity ligands has always been the development focus of affinity chromatography. Previous antibody affinity ligand designs were mostly based on the crystal structure of protein A (UniProt code number: P38507), and the antibody-binding domains were modified according to the properties of amino acid residues. Currently, more effective bioinformatic prediction and experimental validation has been used to improve the design of antibody affinity ligands. In the present study, the complex crystal structure (the domain D of protein A and the Fab segment of IgM, PDB code: 1DEE) was used as the model. The vital site that inhibits the binding between domain D and IgM was estimated by means of molecular dynamics (MD) simulation, then MM-GBSA calculations were used to design a mutant of domain D (K46E) for improving affinity on the above vital site. The binding analysis using Biacore showed the association and dissociation parameters of K46E mutant that were optimized with IgM. The affinity increase of K46E mutant preferred for IgM, the affinity order is K46E tetramer (KD=6.02×10(-9)M)>K46E mutant (KD=6.66×10(-8)M)>domain D (KD=2.17×10(-7)M). Similar results were obtained when the optimized ligands were immobilized to the chromatography medium. A complete designing strategy was validated in this study, which will provide a novel insight into designing new ligands of antibody affinity chromatography media.
Dai, Lu; Li, Weikang; Sun, Fei; Li, Baizhi; Li, Hongrui; Zhang, Hongxing; Zheng, Qingchuan; Liang, Chongyang
2016-09-01
Designing affinity ligands has always been the development focus of affinity chromatography. Previous antibody affinity ligand designs were mostly based on the crystal structure of protein A (UniProt code number: P38507), and the antibody-binding domains were modified according to the properties of amino acid residues. Currently, more effective bioinformatic prediction and experimental validation has been used to improve the design of antibody affinity ligands. In the present study, the complex crystal structure (the domain D of protein A and the Fab segment of IgM, PDB code: 1DEE) was used as the model. The vital site that inhibits the binding between domain D and IgM was estimated by means of molecular dynamics (MD) simulation, then MM-GBSA calculations were used to design a mutant of domain D (K46E) for improving affinity on the above vital site. The binding analysis using Biacore showed the association and dissociation parameters of K46E mutant that were optimized with IgM. The affinity increase of K46E mutant preferred for IgM, the affinity order is K46E tetramer (KD=6.02×10(-9)M)>K46E mutant (KD=6.66×10(-8)M)>domain D (KD=2.17×10(-7)M). Similar results were obtained when the optimized ligands were immobilized to the chromatography medium. A complete designing strategy was validated in this study, which will provide a novel insight into designing new ligands of antibody affinity chromatography media. PMID:27524303
A Field Study on the Raindrop Fall Velocity
NASA Astrophysics Data System (ADS)
Rahman, Kalimur; Testik, Firat
2016-04-01
Raindrop fall velocity is a critical parameter in various rainfall related applications such as dual-polarization radar rainfall estimation. In such applications, it is typically assumed that raindrops fall at terminal velocity. Recent field observations, however, challenged this assumption of terminal raindrops. In this study, we investigated raindrop fall velocity in rainfall events using a new optical-type disdrometer called the High-speed Optical Disdrometer (HOD). We developed the HOD recently for precipitation microphysical observations, in particular for investigating raindrop dynamics including raindrop fall velocity. Our field observations showed clear deviations of raindrop fall velocities from predicted terminal velocities. These new field observations and our ongoing efforts to elucidate raindrop fall velocity characteristics will be discussed. This material is based upon work supported by the National Science Foundation under Grant No. AGS-1612681.
NASA Astrophysics Data System (ADS)
Masson, R.; Bornert, M.; Suquet, P.; Zaoui, A.
2000-06-01
Variational approaches for nonlinear elasticity show that Hill's incremental formulation for the prediction of the overall behaviour of heterogeneous materials yields estimates which are too stiff and may even violate rigorous bounds. This paper aims at proposing an alternative 'affine' formulation, based on a linear thermoelastic comparison medium, which could yield softer estimates. It is first described for nonlinear elasticity and specified by making use of Hashin-Shtrikman estimates for the linear comparison composite; the associated affine self-consistent predictions are satisfactorily compared with incremental and tangent ones for power-law creeping polycrystals. Comparison is then made with the second-order procedure (Ponte Castañeda, P., 1996. Exact second-order estimates for the effective mechanical properties of nonlinear composite materials. J. Mech. Phys. Solids, 44 (6), 827-862) and some limitations of the affine method are pointed out; explicit comparisons between different procedures are performed for isotropic, two-phase materials. Finally, the affine formulation is extended to history-dependent behaviours; application to the self-consistent modelling of the elastoplastic behaviour of polycrystals shows that it offers an improved alternative to Hill's incremental formulation.
Proton and sodium cation affinities of harpagide: a computational study.
Colas, Cyril; Bouchonnet, Stéphane; Rogalewicz-Gilard, Françoise; Popot, Marie-Agnès; Ohanessian, Gilles
2006-06-15
The aim of this work was to estimate the proton and sodium cation affinities of harpagide (Har), an iridoid glycoside responsible for the antiinflammatory properties of the medicinal plant Harpagophytum. Monte Carlo conformational searches were performed at the semiempirical AM1 level to determine the most stable conformers for harpagide and its protonated and Na+-cationized forms. The 10 oxygen atoms of the molecule were considered as possible protonation and cationization sites. Geometry optimizations were then refined at the DFT B3LYP/6-31G level from the geometries of the most stable conformers found. Final energetics were obtained at the B3LYP/6-311+G(2d,2p)//B3LYP/6-31G level. The proton and sodium ion affinities of harpagide have been estimated at 223.5 and 66.0 kcal/mol, respectively. Since harpagide mainly provides HarNa+ ions in electrospray experiments, the DeltarG298 associated with the reaction of proton/sodium exchange between Har and methanol, MeOHNa+ + HarH+ --> MeOH2+ + HarNa+ (1), has been calculated; it has been estimated to be 1.9 kcal/mol. Complexing a methanol molecule to each reagent and product of reaction 1 makes the reaction become exothermic by 1.7 kcal/mol. These values are in the limit of the accuracy of the method and do not allow us to conclude definitely whether the reaction is endo- or exothermic, but, according to these very small values, the cation exchange reaction is expected to proceed easily in the final stages of the ion desolvation process. PMID:16759142
Acoustic velocity meter systems
Laenen, Antonius
1985-01-01
Acoustic velocity meter (AVM) systems operate on the principles that the point-to-point upstream traveltime of an acoustic pulse is longer than the downstream traveltime and that this difference in traveltime can be accurately measured by electronic devices. An AVM system is capable of recording water velocity (and discharge) under a wide range of conditions, but some constraints apply: 1. Accuracy is reduced and performance is degraded if the acoustic path is not a continuous straight line. The path can be bent by reflection if it is too close to a stream boundary or by refraction if it passes through density gradients resulting from variations in either water temperature or salinity. For paths of less than 100 m, a temperature gradient of 0.1' per meter causes signal bending less than 0.6 meter at midchannel, and satisfactory velocity results can be obtained. Reflection from stream boundaries can cause signal cancellation if boundaries are too close to signal path. 2. Signal strength is attenuated by particles or bubbles that absorb, spread, or scatter sound. The concentration of particles or bubbles that can be tolerated is a function of the path length and frequency of the acoustic signal. 3. Changes in streamline orientation can affect system accuracy if the variability is random. 4. Errors relating to signal resolution are much larger for a single threshold detection scheme than for multiple threshold schemes. This report provides methods for computing the effect of various conditions on the accuracy of a record obtained from an AVM. The equipment must be adapted to the site. Field reconnaissance and preinstallation analysis to detect possible problems are critical for proper installation and operation of an AVM system.
Dark Matter Velocity Spectroscopy.
Speckhard, Eric G; Ng, Kenny C Y; Beacom, John F; Laha, Ranjan
2016-01-22
Dark matter decays or annihilations that produce linelike spectra may be smoking-gun signals. However, even such distinctive signatures can be mimicked by astrophysical or instrumental causes. We show that velocity spectroscopy-the measurement of energy shifts induced by relative motion of source and observer-can separate these three causes with minimal theoretical uncertainties. The principal obstacle has been energy resolution, but upcoming experiments will have the precision needed. As an example, we show that the imminent Astro-H mission can use Milky Way observations to separate possible causes of the 3.5-keV line. We discuss other applications. PMID:26849582
Dark Matter Velocity Spectroscopy.
Speckhard, Eric G; Ng, Kenny C Y; Beacom, John F; Laha, Ranjan
2016-01-22
Dark matter decays or annihilations that produce linelike spectra may be smoking-gun signals. However, even such distinctive signatures can be mimicked by astrophysical or instrumental causes. We show that velocity spectroscopy-the measurement of energy shifts induced by relative motion of source and observer-can separate these three causes with minimal theoretical uncertainties. The principal obstacle has been energy resolution, but upcoming experiments will have the precision needed. As an example, we show that the imminent Astro-H mission can use Milky Way observations to separate possible causes of the 3.5-keV line. We discuss other applications.
NASA Astrophysics Data System (ADS)
Biagetti, Matteo; Desjacques, Vincent; Kehagias, Alex; Riotto, Antonio
2014-11-01
It has been recently shown that any halo velocity bias present in the initial conditions does not decay to unity, in agreement with predictions from peak theory. However, this is at odds with the standard formalism based on the coupled-fluids approximation for the coevolution of dark matter and halos. Starting from conservation laws in phase space, we discuss why the fluid momentum conservation equation for the biased tracers needs to be modified in accordance with the change advocated in Baldauf et al. Our findings indicate that a correct description of the halo properties should properly take into account peak constraints when starting from the Vlasov-Boltzmann equation.
NASA Astrophysics Data System (ADS)
Legendre, R.
1992-09-01
Different types of aerodynamically generated noise of practical interest are examined using a novel, physically based, approach. A simple source model for turbulence noise is proposed. The prediction for turbulent mixing layer noise, produced by this model based on a simple monopole-type source mechanism, is that the radiated sound power varies as the eighth power of the relative velocity. The model is too simple to allow calculations to be carried further to the extent of determining the radiated sound power level, so that an empirical factor must still be considered, as in the case of Lighthill's formula.
Multiresolution parametric estimation of transparent motions and denoising of fluoroscopic images.
Auvray, Vincent; Liénard, Jean; Bouthemy, Patrick
2005-01-01
We describe a novel multiresolution parametric framework to estimate transparent motions typically present in X-Ray exams. Assuming the presence if two transparent layers, it computes two affine velocity fields by minimizing an appropriate objective function with an incremental Gauss-Newton technique. We have designed a realistic simulation scheme of fluoroscopic image sequences to validate our method on data with ground truth and different levels of noise. An experiment on real clinical images is also reported. We then exploit this transparent-motion estimation method to denoise two layers image sequences using a motion-compensated estimation method. In accordance with theory, we show that we reach a denoising factor of 2/3 in a few iterations without bringing any local artifacts in the image sequence.
Li, Shangyong; Wang, Linna; Yang, Juan; Bao, Jing; Liu, Junzhong; Lin, Shengxiang; Hao, Jianhua; Sun, Mi
2016-06-01
In this study, an efficient affinity purification protocol for an alkaline metalloprotease from marine bacterium was developed using immobilized metal affinity chromatography. After screening and optimization of the affinity ligands and spacer arm lengths, Cu-iminmodiacetic acid was chosen as the optimal affinity ligand, which was coupled to Sepharose 6B via a 14-atom spacer arm. The absorption analysis of this medium revealed a desorption constant Kd of 21.5 μg/mL and a theoretical maximum absorption Qmax of 24.9 mg/g. Thanks to this affinity medium, the enzyme could be purified by only one affinity purification step with a purity of approximately 95% pure when analyzed by high-performance liquid chromatography and reducing sodium dodecyl sulfate polyacrylamide gel electrophoresis. The recovery of the protease activity reached 74.6%, which is much higher than the value obtained by traditional protocols (8.9%). These results contribute to the industrial purifications and contribute a significant reference for the purification of other metalloproteases. PMID:27058973
A modified full velocity difference model with the consideration of velocity deviation
NASA Astrophysics Data System (ADS)
Zhou, Jie; Shi, Zhong-Ke
2016-01-01
In this paper, a modified full velocity difference model (FVDM) based on car-following theory is proposed with the consideration of velocity deviation which represents the inexact judgement of velocity. The stability condition is obtained by the use of linear stability analysis. It is shown that the stability of traffic flow varies with the deviation extent of velocity. The Burgers, Korteweg-de Vries (KdV) and modified K-dV (MKdV) equations are derived to describe the triangular shock waves, soliton waves and kink-antikink waves in the stable, metastable and unstable region, respectively. The numerical simulations show a good agreement with the analytical results, such as density wave, hysteresis loop, acceleration, deceleration and so on. The results show that traffic congestion can be suppressed by taking the positive effect of velocity deviation into account. By taking the positive effect of high estimate of velocity into account, the unrealistic high deceleration and negative velocity which occur in FVDM will be eliminated in the proposed model.
Characterization of methacrylate chromatographic monoliths bearing affinity ligands.
Černigoj, Urh; Vidic, Urška; Nemec, Blaž; Gašperšič, Jernej; Vidič, Jana; Lendero Krajnc, Nika; Štrancar, Aleš; Podgornik, Aleš
2016-09-16
We investigated effect of immobilization procedure and monolith structure on chromatographic performance of methacrylate monoliths bearing affinity ligands. Monoliths of different pore size and various affinity ligands were prepared and characterized using physical and chromatographic methods. When testing protein A monoliths with different protein A ligand densities, a significant nonlinear effect of ligand density on dynamic binding capacity (DBC) for IgG was obtained and accurately described by Langmuir isotherm curve enabling estimation of protein A utilization as a function of ligand density. Maximal IgG binding capacity was found to be at least 12mg/mL exceeding theoretical monolayer adsorption value of 7.8mg/mL assuming hexagonal packing and IgG hydrodynamic diameter of 11nm. Observed discrepancy was explained by shrinkage of IgG during adsorption on protein A experimentally determined through calculated adsorbed IgG layer thickness of 5.4nm from pressure drop data. For monoliths with different pore size maximal immobilized densities of protein A as well as IgG dynamic capacity linearly correlates with monolith surface area indicating constant ligand utilization. Finally, IgGs toward different plasma proteins were immobilized via the hydrazide coupling chemistry to provide oriented immobilization. DBC was found to be flow independent and was increasing with the size of bound protein. Despite DBC was lower than IgG capacity to immobilized protein A, ligand utilization was higher. PMID:27554023
Concurrent low- and high-affinity sulfate reduction kinetics in marine sediment
NASA Astrophysics Data System (ADS)
Harder Tarpgaard, Irene; Røy, Hans; Jørgensen, Bo Barker
Bacterial sulfate reduction in marine sediments generally occurs in the presence of high millimolar concentrations of sulfate. Published data indicate that low sulfate concentrations may limit sulfate reduction rates below 0.2-2 mM. Yet, high sulfate reduction rates occur in the 1-100 μM range in freshwater sediments and at the sulfate-methane transition in marine sediments. Through a combination of 35S-tracer experiments, including initial velocity experiments and time course experiments, we searched for different sulfate affinities in the mixed community of sulfate reducers in a marine sediment. We supported the radiotracer experiments with a highly sensitive ion chromatographic technique for sulfate with a detection limit of 0.15 μM SO 42- in marine pore water. Our results showed that high and low affinities for sulfate co-occur and that the applied experimental approach may determine the observed apparent half saturation constant, Km. Our experimental and model data both show that sulfate reduction in the studied marine sediment could be explained by two dominating affinities for sulfate: a low affinity with a mean half saturation constant, Km, of 430 μM SO 42- and a high affinity with a mean Km of 2.6 μM SO 42-. The high-affinity sulfate reduction was thermodynamically un-constrained down to <1 μM SO 42-, both in our experiments and under in situ conditions. The reduction of radio-labeled sulfate was partly reversible due to concurrent re-oxidation of sulfide by Fe(III) and possibly due to a reversibility of the enzymatic pathway of sulfate reduction. A literature survey of apparent Km values for sediments and pure cultures is presented and discussed.
Smooth big bounce from affine quantization
NASA Astrophysics Data System (ADS)
Bergeron, Hervé; Dapor, Andrea; Gazeau, Jean Pierre; Małkiewicz, Przemysław
2014-04-01
We examine the possibility of dealing with gravitational singularities on a quantum level through the use of coherent state or wavelet quantization instead of canonical quantization. We consider the Robertson-Walker metric coupled to a perfect fluid. It is the simplest model of a gravitational collapse, and the results obtained here may serve as a useful starting point for more complex investigations in the future. We follow a quantization procedure based on affine coherent states or wavelets built from the unitary irreducible representation of the affine group of the real line with positive dilation. The main issue of our approach is the appearance of a quantum centrifugal potential allowing for regularization of the singularity, essential self-adjointness of the Hamiltonian, and unambiguous quantum dynamical evolution.
Affinity Chromatography in Nonionic Detergent Solutions
NASA Astrophysics Data System (ADS)
Robinson, Jack B.; Strottmann, James M.; Wick, Donald G.; Stellwagen, Earle
1980-10-01
Anionic dye affinity chromatography is commonly unproductive in the presence of nonionic detergents used to extract particulate proteins. Using lactate dehydrogenase as a model protein, Cibacron blue F3GA as a model dye, and Triton X-100 as a model detergent, we find that the dye is encapsulated in nonionic detergent micelles, rendering the dye incapable of ligation with the enzyme. However, the dye can be liberated from the micelles without altering the nonionic detergent concentration by addition of an anionic detergent, such as deoxycholate or sodium dodecyl sulfate, forming mixed anionic/nonionic micelles that displace the anionic dye. Encapsulation of the anionic detergents prevents their activity as protein denaturants. These observations have been successfully translated to the dye affinity chromatography of a detergent extract of brain particulate cyclic nucleotide phosphodiesterase.
Artificial Affinity Proteins as Ligands of Immunoglobulins
Mouratou, Barbara; Béhar, Ghislaine; Pecorari, Frédéric
2015-01-01
A number of natural proteins are known to have affinity and specificity for immunoglobulins. Some of them are widely used as reagents for detection or capture applications, such as Protein G and Protein A. However, these natural proteins have a defined spectrum of recognition that may not fit specific needs. With the development of combinatorial protein engineering and selection techniques, it has become possible to design artificial affinity proteins with the desired properties. These proteins, termed alternative scaffold proteins, are most often chosen for their stability, ease of engineering and cost-efficient recombinant production in bacteria. In this review, we focus on alternative scaffold proteins for which immunoglobulin binders have been identified and characterized. PMID:25647098
Permeability of self-affine rough fractures
Drazer; Koplik
2000-12-01
The permeability of two-dimensional fractures with self-affine fractal roughness is studied via analytic arguments and numerical simulations. The limit where the roughness amplitude is small compared with average fracture aperture is analyzed by a perturbation method, while in the opposite case of narrow aperture, we use heuristic arguments based on lubrication theory. Numerical simulations, using the lattice Boltzmann method, are used to examine the complete range of aperture sizes, and confirm the analytic arguments. PMID:11138092
Velocity of magnetic neutral lines in the magnetotail
NASA Astrophysics Data System (ADS)
Shirai, H.; Takada, T. K.; Mukai, T.
The Geotail spacecraft often observed intermittent enhancements of ion density and velocity in the distant (>70 RE) tail lobe [Shirai, H., Takada, T.K., Kamide, Y, Mukai, T. Enhancement of lobe ion density and velocity associated with plasmoids. J. Geophys. Res. 106, 29,935-29,942, 2000]. Each enhancement occurred alter the passage of a plasmoid and was accompanied by a south-to-north variation in Bz. These signatures suggest that a magnetic neutral line formed in the near-Earth region moves tailward after the plasmoid is ejected. In this paper, we analyze the timing of the ion enhancement in detail. From the timing, we estimate the average velocity of the neutral line motion. The estimated velocity is about 130-580 km/s, which is around 20-70% of a typical value of the plasmoid velocity (i.e., about 760 km/s). We also compare the neutral line velocity in the Earth 's magnetotail with the rise velocity of a solar flare loop [Shibata, K., Masuda, S., Shimojo, M, et al., Hot plasma ejection associated with compact-loop solar flares. Ap. J. Lett. 451, L83-L85, 1995]. The neutral line velocity in the magnetotail is larger than the loop velocity (4-20 km/s). However the ratio of the neutral line velocity to the plasmoid velocity in the tail is similar to the ratio of the loop velocity to the plasmoid velocity in solar flares suggesting the presence of the same physical mechanism behind them.
On constructing purely affine theories with matter
NASA Astrophysics Data System (ADS)
Cervantes-Cota, Jorge L.; Liebscher, D.-E.
2016-08-01
We explore ways to obtain the very existence of a space-time metric from an action principle that does not refer to it a priori. Although there are reasons to believe that only a non-local theory can viably achieve this goal, we investigate here local theories that start with Schrödinger's purely affine theory (Schrödinger in Space-time structure. Cambridge UP, Cambridge, 1950), where he gave reasons to set the metric proportional to the Ricci curvature aposteriori. When we leave the context of unified field theory, and we couple the non-gravitational matter using some weak equivalence principle, we can show that the propagation of shock waves does not define a lightcone when the purely affine theory is local and avoids the explicit use of the Ricci tensor in realizing the weak equivalence principle. When the Ricci tensor is substituted for the metric, the equations seem to have only a very limited set of solutions. This backs the conviction that viable purely affine theories have to be non-local.
Overview of affinity biosensors in food analysis.
Patel, Pradip D
2006-01-01
The 4 major driving forces that are expected to lead to increased use of affinity biosensors that meet crucial industrial test specifications, e.g., fast, reliable, cost-effective, and use of low-skilled personnel, are (1) strict legislative framework, e.g., recent changes proposed to the European food safety and hygiene legislation, EC No. 178/2002; (2) industrial shift from quality control to quality assurance procedures, e.g., Hazard Analysis Critical Control Point, ensuring effective positioning in the global competitive trade; (3) just-in-time production resulting in 'right' product every time; and (4) consumer demand for safe and wholesome products. The affinity biosensors field has expanded significantly over the past decade, with a projected global biosensors market growth from $6.1 billion in 2004 to $8.2 billion in 2009, representing major industrial sectors (e.g., Pharma, Medicare, and Food). This brief review is targeted to affinity biosensors developed for the food industry and includes research and development leading to biosensors for microbiological and chemical analytes of industrial concern, commercial biosensors products on the market, and examples of future prospects in this diagnostic field.
Overview of affinity biosensors in food analysis.
Patel, Pradip D
2006-01-01
The 4 major driving forces that are expected to lead to increased use of affinity biosensors that meet crucial industrial test specifications, e.g., fast, reliable, cost-effective, and use of low-skilled personnel, are (1) strict legislative framework, e.g., recent changes proposed to the European food safety and hygiene legislation, EC No. 178/2002; (2) industrial shift from quality control to quality assurance procedures, e.g., Hazard Analysis Critical Control Point, ensuring effective positioning in the global competitive trade; (3) just-in-time production resulting in 'right' product every time; and (4) consumer demand for safe and wholesome products. The affinity biosensors field has expanded significantly over the past decade, with a projected global biosensors market growth from $6.1 billion in 2004 to $8.2 billion in 2009, representing major industrial sectors (e.g., Pharma, Medicare, and Food). This brief review is targeted to affinity biosensors developed for the food industry and includes research and development leading to biosensors for microbiological and chemical analytes of industrial concern, commercial biosensors products on the market, and examples of future prospects in this diagnostic field. PMID:16792079
A MEMS Dielectric Affinity Glucose Biosensor
Huang, Xian; Li, Siqi; Davis, Erin; Li, Dachao; Wang, Qian; Lin, Qiao
2013-01-01
Continuous glucose monitoring (CGM) sensors based on affinity detection are desirable for long-term and stable glucose management. However, most affinity sensors contain mechanical moving structures and complex design in sensor actuation and signal readout, limiting their reliability in subcutaneously implantable glucose detection. We have previously demonstrated a proof-of-concept dielectric glucose sensor that measured pre-mixed glucose-sensitive polymer solutions at various glucose concentrations. This sensor features simplicity in sensor design, and possesses high specificity and accuracy in glucose detection. However, lack of glucose diffusion passage, this device is unable to fulfill real-time in-vivo monitoring. As a major improvement to this device, we present in this paper a fully implantable MEMS dielectric affinity glucose biosensor that contains a perforated electrode embedded in a suspended diaphragm. This capacitive-based sensor contains no moving parts, and enables glucose diffusion and real-time monitoring. The experimental results indicate that this sensor can detect glucose solutions at physiological concentrations and possesses good reversibility and reliability. This sensor has a time constant to glucose concentration change at approximately 3 min, which is comparable to commercial systems. The sensor has potential applications in fully implantable CGM that require excellent long-term stability and reliability. PMID:24511215
Phosphopeptide Enrichment by Immobilized Metal Affinity Chromatography.
Thingholm, Tine E; Larsen, Martin R
2016-01-01
Immobilized metal affinity chromatography (IMAC) has been the method of choice for phosphopeptide enrichment prior to mass spectrometric analysis for many years and it is still used extensively in many laboratories. Using the affinity of negatively charged phosphate groups towards positively charged metal ions such as Fe(3+), Ga(3+), Al(3+), Zr(4+), and Ti(4+) has made it possible to enrich phosphorylated peptides from peptide samples. However, the selectivity of most of the metal ions is limited, when working with highly complex samples, e.g., whole-cell extracts, resulting in contamination from nonspecific binding of non-phosphorylated peptides. This problem is mainly caused by highly acidic peptides that also share high binding affinity towards these metal ions. By lowering the pH of the loading buffer nonspecific binding can be reduced significantly, however with the risk of reducing specific binding capacity. After binding, the enriched phosphopeptides are released from the metal ions using alkaline buffers of pH 10-11, EDTA, or phosphate-containing buffers. Here we describe a protocol for IMAC using Fe(3+) for phosphopeptide enrichment. The principles are illustrated on a semi-complex peptide mixture. PMID:26584922
Trematode hemoglobins show exceptionally high oxygen affinity.
Kiger, L; Rashid, A K; Griffon, N; Haque, M; Moens, L; Gibson, Q H; Poyart, C; Marden, M C
1998-08-01
Ligand binding studies were made with hemoglobin (Hb) isolated from trematode species Gastrothylax crumenifer (Gc), Paramphistomum epiclitum (Pe), Explanatum explanatum (Ee), parasitic worms of water buffalo Bubalus bubalis, and Isoparorchis hypselobagri (Ih) parasitic in the catfish Wallago attu. The kinetics of oxygen and carbon monoxide binding show very fast association rates. Whereas oxygen can be displaced on a millisecond time scale from human Hb at 25 degrees C, the dissociation of oxygen from trematode Hb may require a few seconds to over 20 s (for Hb Pe). Carbon monoxide dissociation is faster, however, than for other monomeric hemoglobins or myoglobins. Trematode hemoglobins also show a reduced rate of autoxidation; the oxy form is not readily oxidized by potassium ferricyanide, indicating that only the deoxy form reacts rapidly with this oxidizing agent. Unlike most vertebrate Hbs, the trematodes have a tyrosine residue at position E7 instead of the usual distal histidine. As for Hb Ascaris, which also displays a high oxygen affinity, the trematodes have a tyrosine in position B10; two H-bonds to the oxygen molecule are thought to be responsible for the very high oxygen affinity. The trematode hemoglobins display a combination of high association rates and very low dissociation rates, resulting in some of the highest oxygen affinities ever observed.
The velocity distribution of cometary hydrogen - Evidence for high velocities?
NASA Technical Reports Server (NTRS)
Brown, Michael E.; Spinrad, Hyron
1993-01-01
The Hamilton Echelle spectrograph on the 3-m Shane telescope at Lick Observatory was used to obtain high-velocity and spatial resolution 2D spectra of H-alpha 6563-A emission in Comets Austin and Levy. The presence of the components expected from water dissociation and collisional thermalization in the inner coma is confirmed by the hydrogen velocity distribution. In Comet Austin, the potential high-velocity hydrogen includes velocities of up to about 40 km/s and is spatially symmetric with respect to the nucleus. In Comet Levy, the high-velocity hydrogen reaches velocities of up to 50 km/s and is situated exclusively on the sunward side of the nucleus. The two distinct signatures of high-velocity hydrogen imply two distinct sources.
Doppler Lidar Vertical Velocity Statistics Value-Added Product
Newsom, R. K.; Sivaraman, C.; Shippert, T. R.; Riihimaki, L. D.
2015-07-01
Accurate height-resolved measurements of higher-order statistical moments of vertical velocity fluctuations are crucial for improved understanding of turbulent mixing and diffusion, convective initiation, and cloud life cycles. The Atmospheric Radiation Measurement (ARM) Climate Research Facility operates coherent Doppler lidar systems at several sites around the globe. These instruments provide measurements of clear-air vertical velocity profiles in the lower troposphere with a nominal temporal resolution of 1 sec and height resolution of 30 m. The purpose of the Doppler lidar vertical velocity statistics (DLWSTATS) value-added product (VAP) is to produce height- and time-resolved estimates of vertical velocity variance, skewness, and kurtosis from these raw measurements. The VAP also produces estimates of cloud properties, including cloud-base height (CBH), cloud frequency, cloud-base vertical velocity, and cloud-base updraft fraction.
Unitaxial constant velocity microactuator
McIntyre, Timothy J.
1994-01-01
A uniaxial drive system or microactuator capable of operating in an ultra-high vacuum environment. The mechanism includes a flexible coupling having a bore therethrough, and two clamp/pusher assemblies mounted in axial ends of the coupling. The clamp/pusher assemblies are energized by voltage-operated piezoelectrics therewithin to operatively engage the shaft and coupling causing the shaft to move along its rotational axis through the bore. The microactuator is capable of repeatably positioning to sub-manometer accuracy while affording a scan range in excess of 5 centimeters. Moreover, the microactuator generates smooth, constant velocity motion profiles while producing a drive thrust of greater than 10 pounds. The system is remotely controlled and piezoelectrically driven, hence minimal thermal loading, vibrational excitation, or outgassing is introduced to the operating environment.
Unitaxial constant velocity microactuator
McIntyre, T.J.
1994-06-07
A uniaxial drive system or microactuator capable of operating in an ultra-high vacuum environment is disclosed. The mechanism includes a flexible coupling having a bore therethrough, and two clamp/pusher assemblies mounted in axial ends of the coupling. The clamp/pusher assemblies are energized by voltage-operated piezoelectrics therewithin to operatively engage the shaft and coupling causing the shaft to move along its rotational axis through the bore. The microactuator is capable of repeatably positioning to sub-nanometer accuracy while affording a scan range in excess of 5 centimeters. Moreover, the microactuator generates smooth, constant velocity motion profiles while producing a drive thrust of greater than 10 pounds. The system is remotely controlled and piezoelectrically driven, hence minimal thermal loading, vibrational excitation, or outgassing is introduced to the operating environment. 10 figs.
Velocity acceleration as a determinant of flow-mediated dilation.
Stoner, Lee; McCully, Kevin K
2012-04-01
Shear stress is the established stimulus for flow-mediated dilation (FMD). In vivo, shear stress is typically estimated using mean blood velocity. However, mean blood velocity may not adequately characterize the shear stimulus. Pulsatile flow results in large shear gradients (velocity acceleration) at the onset of flow. The purpose of this study was to determine the importance of velocity acceleration to FMD. We define FMD as the brachial artery shear rate-diameter slope. Fourteen physically active, young (26 ± 5 years), male subjects were tested. Progressive forearm heating and handgrip exercise elicited steady-state increases in shear rate. FMD was measured prior to and following induced increases in velocity acceleration. Velocity acceleration was increased by inflating a tourniquet around the forearm to 40 mm Hg. Hierarchical linear modeling was used to estimate change in diameter with repeated measures of shear stress nested within each subject. Averaged across conditions, the 40 mm Hg cuff resulted in a 14% increase in velocity acceleration (p = 0.001). FMD was attenuated by 11.0% (p = 0.015) for the acceleration vs. control condition. However, after specifying velocity acceleration as a covariate, FMD was no longer significantly (p = 0.619) different between acceleration and control conditions. This finding suggests that mean blood velocity alone may not adequately characterize the shear stimulus.
Kong, Gang; Dai, Dao-Qing; Zou, Lu-Min
2008-07-01
In order to remove the artifacts of peripheral digital subtraction angiography (DSA), an affine transformation-based automatic image registration algorithm is introduced here. The whole process is described as follows: First, rectangle feature templates are constructed with their centers of the extracted Harris corners in the mask, and motion vectors of the central feature points are estimated using template matching technology with the similarity measure of maximum histogram energy. And then the optimal parameters of the affine transformation are calculated with the matrix singular value decomposition (SVD) method. Finally, bilinear intensity interpolation is taken to the mask according to the specific affine transformation. More than 30 peripheral DSA registrations are performed with the presented algorithm, and as the result, moving artifacts of the images are removed with sub-pixel precision, and the time consumption is less enough to satisfy the clinical requirements. Experimental results show the efficiency and robustness of the algorithm.
Dynamical surface affinity of diphasic liquids as a probe of wettability of multimodal porous media.
Korb, J-P; Freiman, G; Nicot, B; Ligneul, P
2009-12-01
We introduce a method for estimating the wettability of rock/oil/brine systems using noninvasive in situ nuclear magnetic relaxation dispersion. This technique scans over a large range of applied magnetic fields and yields unique information about the extent to which a fluid is dynamically correlated with a solid rock surface. Unlike conventional transverse relaxation studies, this approach is a direct probe of the dynamical surface affinity of fluids. To quantify these features we introduce a microscopic dynamical surface affinity index which measures the dynamical correlation (i.e., the microscopic wettability) between the diffusive fluid and the fixed paramagnetic relaxation sources at the pore surfaces. We apply this method to carbonate reservoir rocks which are known to hold about two thirds of the world's oil reserves. Although this nondestructive method concerns here an application to rocks, it could be generalized as an in situ liquid/surface affinity indicator for any multimodal porous medium including porous biological media. PMID:20365175
A new car-following model considering velocity anticipation
NASA Astrophysics Data System (ADS)
Tian, Jun-Fang; Jia, Bin; Li, Xin-Gang; Gao, Zi-You
2010-01-01
The full velocity difference model proposed by Jiang et al. [2001 Phys. Rev. E 64 017101] has been improved by introducing velocity anticipation. Velocity anticipation means the follower estimates the future velocity of the leader. The stability condition of the new model is obtained by using the linear stability theory. Theoretical results show that the stability region increases when we increase the anticipation time interval. The mKdV equation is derived to describe the kink-antikink soliton wave and obtain the coexisting stability line. The delay time of car motion and kinematic wave speed at jam density are obtained in this model. Numerical simulations exhibit that when we increase the anticipation time interval enough, the new model could avoid accidents under urgent braking cases. Also, the traffic jam could be suppressed by considering the anticipation velocity. All results demonstrate that this model is an improvement on the full velocity difference model.
An improved car-following model considering relative velocity fluctuation
NASA Astrophysics Data System (ADS)
Yu, Shaowei; Shi, Zhongke
2016-07-01
To explore and evaluate the impacts of relative velocity fluctuation on the dynamic characteristics and fuel consumptions of traffic flow, we present an improved car-following model considering relative velocity fluctuation based on the full velocity difference model, then we carry out several numerical simulations to determine the optimal time window length and to explore how relative velocity fluctuation affects cars' velocity and its fluctuation as well as fuel consumptions. It can be found that the improved car-following model can describe the phase transition of traffic flow and estimate the evolution of traffic congestion, and that taking relative velocity fluctuation into account in designing the advanced adaptive cruise control strategy can improve the traffic flow stability and reduce fuel consumptions.
ITRF2014 vertical velocities: the impact of climate changes
NASA Astrophysics Data System (ADS)
Rebischung, P.; Metivier, L.; Altamimi, Z.
2015-12-01
We investigate the GNSS station vertical velocities provided by the new solution of the International Terrestrial Reference Frame, the ITRF2014. Constructed, inter alia, from a network of approximately 1000 GNSS stations, this new solution provides two times more station velocities than the ITRF2008, and shows a global pattern of vertical velocities very homogeneous regionally. As in the ITRF2008 solution, large vertical velocities can be seen over North America, Northern Europe, or Antarctica, probably induced predominantly by the Glacial Isostatic Adjustment still occurring today since the last deglaciation. But the ITRF2014 solution shows also large vertical velocities over regions such as Greenland and Alaska clearly larger than in the ITRF2008, probably related to last decadal ice melting and its possible acceleration. We focus here on this specific difference between the ITRF2008 and ITRF2014 solutions by investigating the global Earth figure variations through the estimation of low degree spherical harmonics of the global vertical velocity field.
Jain, Tarun; Jayaram, B
2007-06-01
Zinc is one of the most important metal ions found in proteins performing specific functions associated with life processes. Coordination geometry of the zinc ion in the active site of the metalloprotein-ligand complexes poses a challenge in determining ligand binding affinities accurately in structure-based drug design. We report here an all atom force field based computational protocol for estimating rapidly the binding affinities of zinc containing metalloprotein-ligand complexes, considering electrostatics, van der Waals, hydrophobicity, and loss in conformational entropy of protein side chains upon ligand binding along with a nonbonded approach to model the interactions of the zinc ion with all the other atoms of the complex. We examined the sensitivity of the binding affinity predictions to the choice of Lennard-Jones parameters, partial atomic charges, and dielectric treatments adopted for system preparation and scoring. The highest correlation obtained was R2 = 0.77 (r = 0.88) for the predicted binding affinity against the experiment on a heterogenous dataset of 90 zinc containing metalloprotein-ligand complexes consisting of five unique protein targets. Model validation and parameter analysis studies underscore the robustness and predictive ability of the scoring function. The high correlation obtained suggests the potential applicability of the methodology in designing novel ligands for zinc-metalloproteins. The scoring function has been web enabled for free access at www.scfbio-iitd.res.in/software/drugdesign/bapplz.jsp as BAPPL-Z server (Binding Affinity Prediction of Protein-Ligand complexes containing Zinc metal ions).
Estimating discharge measurement uncertainty using the interpolated variance estimator
Cohn, T.; Kiang, J.; Mason, R.
2012-01-01
Methods for quantifying the uncertainty in discharge measurements typically identify various sources of uncertainty and then estimate the uncertainty from each of these sources by applying the results of empirical or laboratory studies. If actual measurement conditions are not consistent with those encountered in the empirical or laboratory studies, these methods may give poor estimates of discharge uncertainty. This paper presents an alternative method for estimating discharge measurement uncertainty that uses statistical techniques and at-site observations. This Interpolated Variance Estimator (IVE) estimates uncertainty based on the data collected during the streamflow measurement and therefore reflects the conditions encountered at the site. The IVE has the additional advantage of capturing all sources of random uncertainty in the velocity and depth measurements. It can be applied to velocity-area discharge measurements that use a velocity meter to measure point velocities at multiple vertical sections in a channel cross section.
High Resolution Velocity Structure in Eastern Turkey
Pasyanos, M; Gok, R; Zor, E; Walter, W
2004-09-03
We investigate the crustal and upper mantle structure of eastern Turkey where the Anatolian, Arabian and Eurasian Plates meet and form a complex tectonic structure. The Bitlis suture is a continental collision zone between the Anatolian plateau and the Arabian plate. Broadband data available through the Eastern Turkey Seismic Experiment (ETSE) provided a unique opportunity for studying the high resolution velocity structure. Zor et al. found an average 46 km thick crust in Anatolian plateau using six-layered grid search inversion of the ETSE receiver functions. Receiver functions are sensitive to the velocity contrast of interfaces and the relative travel time of converted and reverberated waves between those interfaces. The interpretation of receiver function alone with many-layered parameterization may result in an apparent depth-velocity tradeoff. In order to improve previous velocity model, we employed the joint inversion method with many layered parameterization of Julia et al. (2000) to the ETSE receiver functions. In this technique, the receiver function and surface-wave observations are combined into a single algebraic equation and each data set is weighted by an estimate of the uncertainty in the observations. We consider azimuthal changes of receiver functions and have stacked them into different groups. We calculated the receiver functions using iterative time-domain deconvolution technique and surface wave group velocity dispersion curves between 10-100 sec. We are making surface wave dispersion measurements at the ETSE stations and have incorporated them into a regional group velocity model. Preliminary results indicate a strong trend in the long period group velocity in the northeast. This indicates slow upper mantle velocities in the region consistent with Pn, Sn and receiver function results. We started with both the 1-D model that is obtained with the 12 tones dam explosion shot data recorded by ETSE network and the existing receiver function
A simple method of predicting S-wave velocity
Lee, M.W.
2006-01-01
Prediction of shear-wave velocity plays an important role in seismic modeling, amplitude analysis with offset, and other exploration applications. This paper presents a method for predicting S-wave velocity from the P-wave velocity on the basis of the moduli of dry rock. Elastic velocities of water-saturated sediments at low frequencies can be predicted from the moduli of dry rock by using Gassmann's equation; hence, if the moduli of dry rock can be estimated from P-wave velocities, then S-wave velocities easily can be predicted from the moduli. Dry rock bulk modulus can be related to the shear modulus through a compaction constant. The numerical results indicate that the predicted S-wave velocities for consolidated and unconsolidated sediments agree well with measured velocities if differential pressure is greater than approximately 5 MPa. An advantage of this method is that there are no adjustable parameters to be chosen, such as the pore-aspect ratios required in some other methods. The predicted S-wave velocity depends only on the measured P-wave velocity and porosity. ?? 2006 Society of Exploration Geophysicists.
Latest European coelacanth shows Gondwanan affinities.
Cavin, Lionel; Forey, Peter L; Buffetaut, Eric; Tong, Haiyan
2005-06-22
The last European fossil occurrence of a coelacanth is from the Mid-Cretaceous of the English Chalk (Turonian, 90 million years ago). Here, we report the discovery of a coelacanth from Late Cretaceous non-marine rocks in southern France. It consists of a left angular bone showing structures that imply close phylogenetic affinities with some extinct Mawsoniidae. The closest relatives are otherwise known from Cretaceous continental deposits of southern continents and suggest that the dispersal of freshwater organisms from Africa to Europe occurred in the Late Cretaceous.
Hydrokinetic canal measurements: inflow velocity, wake flow velocity, and turbulence
Gunawan, Budi
2014-06-11
The dataset consist of acoustic Doppler current profiler (ADCP) velocity measurements in the wake of a 3-meter diameter vertical-axis hydrokinetic turbine deployed in Roza Canal, Yakima, WA, USA. A normalized hub-centerline wake velocity profile and two cross-section velocity contours, 10 meters and 20 meters downstream of the turbine, are presented. Mean velocities and turbulence data, measured using acoustic Doppler velocimeter (ADV) at 50 meters upstream of the turbine, are also presented. Canal dimensions and hydraulic properties, and turbine-related information are also included.
On the structure of self-affine convex bodies
Voynov, A S
2013-08-31
We study the structure of convex bodies in R{sup d} that can be represented as a union of their affine images with no common interior points. Such bodies are called self-affine. Vallet's conjecture on the structure of self-affine bodies was proved for d = 2 by Richter in 2011. In the present paper we disprove the conjecture for all d≥3 and derive a detailed description of self-affine bodies in R{sup 3}. Also we consider the relation between properties of self-affine bodies and functional equations with a contraction of an argument. Bibliography: 10 titles.
Measuring an antibody affinity distribution molecule by molecule.
Temirov, Jamshid P; Bradbury, Andrew R M; Werner, James H
2008-11-15
Single molecule fluorescence microscopy was used to observe the binding and unbinding of hapten decorated quantum dots to individual surface immobilized antibodies. The fluorescence time history from an individual antibody site can be used to calculate its binding affinity. While quantum dot blinking occurs during these measurements, we describe a simple empirical method to correct the apparent/observed affinity to account for the blinking contribution. The combination of many single molecule affinity measurements from different antibodies yields not only the average affinity, it directly measures the full shape and character of the surface affinity distribution function.
Measuring an antibody affinity distribution molecule by molecule
Bradbury, Andrew M; Werner, James H; Temirov, Jamshid
2008-01-01
Single molecule fluorescence mIcroscopy was used to observe the binding and unbinding of hapten decorated quantum dots with individual surface immobilized antibodies. The fluorescence time history from an individual antibody site can be used to calculate its binding affinity. While quantum dot blinking occurs during these measurements, we describe a simple empirical method to correct the apparent/observed affinity to account for the blinking contribution. The combination of many single molecule affinity measurements from different antibodies yields not only the average affinity, it directly measures the full shape and character of the surface affinity distribution function.
Metal-affinity separations: A new dimension in protein processing
Arnold, F.H. )
1991-02-01
Rapid growth in the preparative and high-resolution analytical applications of metal-affinity chromatography demonstrate the appeal of metal recognition as a basis for protein separations. Stable, inexpensive chelated metals effectively mimic biospecific interactions, providing selective ligands for protein binding. This article reviews recent progress in understanding the mechanisms of metal-protein recognition that underlie metal-affinity separations. Also discussed are schemes for integrating metal-affinity purifications into the expression and bioprocessing of recombinant proteins. Promising future developments include new metal-affinity processes for analytical and preparative-scale separations and a range of techniques for enhancing the selectivity of metal-affinity separations.
Particle Velocity Measuring System
NASA Technical Reports Server (NTRS)
Arndt, G. Dickey (Inventor); Carl, James R. (Inventor)
1998-01-01
Method and apparatus are provided for determining the velocity of individual food particles within a liquid/solid food mixture that is cooked by an aseptic cooking method whereby the food mixture is heated as it flows through a flowline. At least one upstream and at least one downstream microwave transducer are provided to determine the minimum possible travel time of the fastest food particle through the flowline. In one embodiment, the upstream detector is not required. In another embodiment, a plurality of small dipole antenna markers are secured to a plurality of food particles to provide a plurality of signals as the markers pass the upstream and downstream transducers. The dipole antenna markers may also include a non-linear element to reradiate a harmonic frequency of a transmitter frequency. Upstream and downstream transducers include dipole antennas that are matched to the impedance of the food slurry and a signal transmission cable by various impedance matching means including unbalanced feed to the antennas.
Velocity dependant splash behaviour
NASA Astrophysics Data System (ADS)
Hamlett, C. A. E.; Shirtcliffe, N. J.; McHale, G.; Ahn, S.; Doerr, S. H.; Bryant, R.; Newton, M. I.
2012-04-01
Extreme soil water repellency can occur in nature via condensation of volatile organic compounds released during wildfires and can lead to increased erosion rate. Such extreme water repellent soil can be classified as superhydrophobic and shares similar chemical and topographical features to specifically designed superhydrophobic surfaces. Previous studies using high speed videography to investigate single droplet impact behaviour on artificial superhydrophobic have revealed three distinct modes of splash behaviour (rebound, pinned and fragmentation) which are dependent on the impact velocity of the droplet. In our studies, using high-speed videography, we show that such splash behaviour can be replicated on fixed 'model' water repellent soils (hydrophobic glass beads/particles). We show that the type of splash behaviour is dependent on both the size and chemical nature of the fixed particles. The particle shape also influences the splash behaviour as shown by drop impact experiments on fixed sand samples. We have also studied soil samples, as collected from the field, which shows that the type of droplet splash behaviour can lead to enhanced soil particle transport.
Avoiding degenerate coframes in an affine gauge approach to quantum gravity
Mielke, E.W.; McCrea, J.D.; Ne`eman, Y.; Hehl, F.W.
1993-04-01
This report discusses the following concepts on quantum gravity: The affine gauge approach; affine gauge transformations versus active differomorphisms; affine gauge approach to quantum gravity with topology change.
Absolute Plate Velocities from Seismic Anisotropy
NASA Astrophysics Data System (ADS)
Kreemer, Corné; Zheng, Lin; Gordon, Richard
2015-04-01
The orientation of seismic anisotropy inferred beneath plate interiors may provide a means to estimate the motions of the plate relative to the sub-asthenospheric mantle. Here we analyze two global sets of shear-wave splitting data, that of Kreemer [2009] and an updated and expanded data set, to estimate plate motions and to better understand the dispersion of the data, correlations in the errors, and their relation to plate speed. We also explore the effect of using geologically current plate velocities (i.e., the MORVEL set of angular velocities [DeMets et al. 2010]) compared with geodetically current plate velocities (i.e., the GSRM v1.2 angular velocities [Kreemer et al. 2014]). We demonstrate that the errors in plate motion azimuths inferred from shear-wave splitting beneath any one tectonic plate are correlated with the errors of other azimuths from the same plate. To account for these correlations, we adopt a two-tier analysis: First, find the pole of rotation and confidence limits for each plate individually. Second, solve for the best fit to these poles while constraining relative plate angular velocities to consistency with the MORVEL relative plate angular velocities. The SKS-MORVEL absolute plate angular velocities (based on the Kreemer [2009] data set) are determined from the poles from eight plates weighted proportionally to the root-mean-square velocity of each plate. SKS-MORVEL indicates that eight plates (Amur, Antarctica, Caribbean, Eurasia, Lwandle, Somalia, Sundaland, and Yangtze) have angular velocities that differ insignificantly from zero. The net rotation of the lithosphere is 0.25±0.11° Ma-1 (95% confidence limits) right-handed about 57.1°S, 68.6°E. The within-plate dispersion of seismic anisotropy for oceanic lithosphere (σ=19.2° ) differs insignificantly from that for continental lithosphere (σ=21.6° ). The between-plate dispersion, however, is significantly smaller for oceanic lithosphere (σ=7.4° ) than for continental
Reconstruction of velocity fields in electromagnetic flow tomography.
Lehtikangas, Ossi; Karhunen, Kimmo; Vauhkonen, Marko
2016-06-28
Electromagnetic flow meters (EMFMs) are the gold standard in measuring flow velocity in process industry. The flow meters can measure the mean flow velocity of conductive liquids and slurries. A drawback of this approach is that the velocity field cannot be determined. Asymmetric axial flows, often encountered in multiphase flows, pipe elbows and T-junctions, are problematic and can lead to serious systematic errors. Recently, electromagnetic flow tomography (EMFT) has been proposed for measuring velocity fields using several coils and a set of electrodes attached to the surface of the pipe. In this work, a velocity field reconstruction method for EMFT is proposed. The method uses a previously developed finite-element-based computational forward model for computing boundary voltages and a Bayesian framework for inverse problems. In the approach, the vz-component of the velocity field along the longitudinal axis of the pipe is estimated on the pipe cross section. Different asymmetric velocity fields encountered near pipe elbows, solids-in-water flows in inclined pipes and in stratified or multiphase flows are tested. The results suggest that the proposed reconstruction method could be used to estimate velocity fields in complicated pipe flows in which the conventional EMFMs have limited accuracy. This article is part of the themed issue 'Supersensing through industrial process tomography'. PMID:27185961
Reconstruction of velocity fields in electromagnetic flow tomography.
Lehtikangas, Ossi; Karhunen, Kimmo; Vauhkonen, Marko
2016-06-28
Electromagnetic flow meters (EMFMs) are the gold standard in measuring flow velocity in process industry. The flow meters can measure the mean flow velocity of conductive liquids and slurries. A drawback of this approach is that the velocity field cannot be determined. Asymmetric axial flows, often encountered in multiphase flows, pipe elbows and T-junctions, are problematic and can lead to serious systematic errors. Recently, electromagnetic flow tomography (EMFT) has been proposed for measuring velocity fields using several coils and a set of electrodes attached to the surface of the pipe. In this work, a velocity field reconstruction method for EMFT is proposed. The method uses a previously developed finite-element-based computational forward model for computing boundary voltages and a Bayesian framework for inverse problems. In the approach, the vz-component of the velocity field along the longitudinal axis of the pipe is estimated on the pipe cross section. Different asymmetric velocity fields encountered near pipe elbows, solids-in-water flows in inclined pipes and in stratified or multiphase flows are tested. The results suggest that the proposed reconstruction method could be used to estimate velocity fields in complicated pipe flows in which the conventional EMFMs have limited accuracy. This article is part of the themed issue 'Supersensing through industrial process tomography'.
Acceleration and Velocity Sensing from Measured Strain
NASA Technical Reports Server (NTRS)
Pak, Chan-Gi; Truax, Roger
2015-01-01
A simple approach for computing acceleration and velocity of a structure from the strain is proposed in this study. First, deflection and slope of the structure are computed from the strain using a two-step theory. Frequencies of the structure are computed from the time histories of strain using a parameter estimation technique together with an autoregressive moving average model. From deflection, slope, and frequencies of the structure, acceleration and velocity of the structure can be obtained using the proposed approach. Simple harmonic motion is assumed for the acceleration computations, and the central difference equation with a linear autoregressive model is used for the computations of velocity. A cantilevered rectangular wing model is used to validate the simple approach. Quality of the computed deflection, acceleration, and velocity values are independent of the number of fibers. The central difference equation with a linear autoregressive model proposed in this study follows the target response with reasonable accuracy. Therefore, the handicap of the backward difference equation, phase shift, is successfully overcome.
Fatigue damage prognosis using affine arithmetic
NASA Astrophysics Data System (ADS)
Gbaguidi, Audrey; Kim, Daewon
2014-02-01
Among the essential steps to be taken in structural health monitoring systems, damage prognosis would be the field that is least investigated due to the complexity of the uncertainties. This paper presents the possibility of using Affine Arithmetic for uncertainty propagation of crack damage in damage prognosis. The structures examined are thin rectangular plates made of titanium alloys with central mode I cracks and a composite plate with an internal delamination caused by mixed mode I and II fracture modes, under a harmonic uniaxial loading condition. The model-based method for crack growth rates are considered using the Paris Erdogan law model for the isotropic plates and the delamination growth law model proposed by Kardomateas for the composite plate. The parameters for both models are randomly taken and their uncertainties are considered as defined by an interval instead of a probability distribution. A Monte Carlo method is also applied to check whether Affine Arithmetic (AA) leads to tight bounds on the lifetime of the structure.
High-affinity Cyclic Peptide Matriptase Inhibitors*
Quimbar, Pedro; Malik, Uru; Sommerhoff, Christian P.; Kaas, Quentin; Chan, Lai Y.; Huang, Yen-Hua; Grundhuber, Maresa; Dunse, Kerry; Craik, David J.; Anderson, Marilyn A.; Daly, Norelle L.
2013-01-01
The type II transmembrane serine protease matriptase is a key activator of multiple signaling pathways associated with cell proliferation and modification of the extracellular matrix. Deregulated matriptase activity correlates with a number of diseases, including cancer and hence highly selective matriptase inhibitors may have therapeutic potential. The plant-derived cyclic peptide, sunflower trypsin inhibitor-1 (SFTI-1), is a promising drug scaffold with potent matriptase inhibitory activity. In the current study we have analyzed the structure-activity relationships of SFTI-1 and Momordica cochinchinensis trypsin inhibitor-II (MCoTI-II), a structurally divergent trypsin inhibitor from Momordica cochinchinensis that also contains a cyclic backbone. We show that MCoTI-II is a significantly more potent matriptase inhibitor than SFTI-1 and that all alanine mutants of both peptides, generated using positional scanning mutagenesis, have decreased trypsin affinity, whereas several mutations either maintain or result in enhanced matriptase inhibitory activity. These intriguing results were used to design one of the most potent matriptase inhibitors known to date with a 290 pm equilibrium dissociation constant, and provide the first indication on how to modulate affinity for matriptase over trypsin in cyclic peptides. This information might be useful for the design of more selective and therapeutically relevant inhibitors of matriptase. PMID:23548907
Exploring Fluorous Affinity by Liquid Chromatography.
Catani, Martina; Guzzinati, Roberta; Marchetti, Nicola; Pasti, Luisa; Cavazzini, Alberto
2015-07-01
Terms such as "fluorous affinity" and "fluorophilicity" have been used to describe the unique partition and sorption properties often exhibited by highly fluorinated organic compounds, that is molecules rich in sp(3) carbon-fluorine bonds. In this work, we made use of a highly fluorinated stationary phase and a series of benzene derivatives to study the effect of one single perfluorinated carbon on the chromatographic behavior and adsorption properties of molecules. For this purpose, the adsorption equilibria of α,α,α-trifluorotoluene, toluene, and other alkylbenzenes have been studied by means of nonlinear chromatography in a variety of acetonitrile/water eluents. Our results reveal that one single perfluorinated carbon is already enough to induce a drastic change in the adsorption properties of molecules on the perfluorinated stationary phase. In particular, it has been found that adsorption is monolayer if the perfluoroalkyl carbon is present but that, when this unit is missing, molecules arrange as multilayer stack structures. These findings can contribute to the understanding of molecular mechanisms of fluorous affinity. PMID:26047527
Affine conformal vectors in space-time
NASA Astrophysics Data System (ADS)
Coley, A. A.; Tupper, B. O. J.
1992-05-01
All space-times admitting a proper affine conformal vector (ACV) are found. By using a theorem of Hall and da Costa, it is shown that such space-times either (i) admit a covariantly constant vector (timelike, spacelike, or null) and the ACV is the sum of a proper affine vector and a conformal Killing vector or (ii) the space-time is 2+2 decomposable, in which case it is shown that no ACV can exist (unless the space-time decomposes further). Furthermore, it is proved that all space-times admitting an ACV and a null covariantly constant vector (which are necessarily generalized pp-wave space-times) must have Ricci tensor of Segré type {2,(1,1)}. It follows that, among space-times admitting proper ACV, the Einstein static universe is the only perfect fluid space-time, there are no non-null Einstein-Maxwell space-times, and only the pp-wave space-times are representative of null Einstein-Maxwell solutions. Otherwise, the space-times can represent anisotropic fluids and viscous heat-conducting fluids, but only with restricted equations of state in each case.
Velocity Dispersions Across Bulge Types
Fabricius, Maximilian; Bender, Ralf; Hopp, Ulrich; Saglia, Roberto; Drory, Niv; Fisher, David
2010-06-08
We present first results from a long-slit spectroscopic survey of bulge kinematics in local spiral galaxies. Our optical spectra were obtained at the Hobby-Eberly Telescope with the LRS spectrograph and have a velocity resolution of 45 km/s (sigma*), which allows us to resolve the velocity dispersions in the bulge regions of most objects in our sample. We find that the velocity dispersion profiles in morphological classical bulge galaxies are always centrally peaked while the velocity dispersion of morphologically disk-like bulges stays relatively flat towards the center--once strongly barred galaxies are discarded.
Global Plate Velocities from the Global Positioning System
NASA Technical Reports Server (NTRS)
Larson, Kristine M.; Freymueller, Jeffrey T.; Philipsen, Steven
1997-01-01
We have analyzed 204 days of Global Positioning System (GPS) data from the global GPS network spanning January 1991 through March 1996. On the basis of these GPS coordinate solutions, we have estimated velocities for 38 sites, mostly located on the interiors of the Africa, Antarctica, Australia, Eurasia, Nazca, North America, Pacific, and South America plates. The uncertainties of the horizontal velocity components range from 1.2 to 5.0 mm/yr. With the exception of sites on the Pacific and Nazca plates, the GPS velocities agree with absolute plate model predictions within 95% confidence. For most of the sites in North America, Antarctica, and Eurasia, the agreement is better than 2 mm/yr. We find no persuasive evidence for significant vertical motions (less than 3 standard deviations), except at four sites. Three of these four were sites constrained to geodetic reference frame velocities. The GPS velocities were then used to estimate angular velocities for eight tectonic plates. Absolute angular velocities derived from the GPS data agree with the no net rotation (NNR) NUVEL-1A model within 95% confidence except for the Pacific plate. Our pole of rotation for the Pacific plate lies 11.5 deg west of the NNR NUVEL-1A pole, with an angular speed 10% faster. Our relative angular velocities agree with NUVEL-1A except for some involving the Pacific plate. While our Pacific-North America angular velocity differs significantly from NUVEL-1A, our model and NUVEL-1A predict very small differences in relative motion along the Pacific-North America plate boundary itself. Our Pacific-Australia and Pacific- Eurasia angular velocities are significantly faster than NUVEL-1A, predicting more rapid convergence at these two plate boundaries. Along the East Pacific Pise, our Pacific-Nazca angular velocity agrees in both rate and azimuth with NUVFL-1A.
Aguda, Adeleke H; Lavallee, Vincent; Cheng, Ping; Bott, Tina M; Meimetis, Labros G; Law, Simon; Nguyen, Nham T; Williams, David E; Kaleta, Jadwiga; Villanueva, Ivan; Davies, Julian; Andersen, Raymond J; Brayer, Gary D; Brömme, Dieter
2016-08-26
Natural products are an important source of novel drug scaffolds. The highly variable and unpredictable timelines associated with isolating novel compounds and elucidating their structures have led to the demise of exploring natural product extract libraries in drug discovery programs. Here we introduce affinity crystallography as a new methodology that significantly shortens the time of the hit to active structure cycle in bioactive natural product discovery research. This affinity crystallography approach is illustrated by using semipure fractions of an actinomycetes culture extract to isolate and identify a cathepsin K inhibitor and to compare the outcome with the traditional assay-guided purification/structural analysis approach. The traditional approach resulted in the identification of the known inhibitor antipain (1) and its new but lower potency dehydration product 2, while the affinity crystallography approach led to the identification of a new high-affinity inhibitor named lichostatinal (3). The structure and potency of lichostatinal (3) was verified by total synthesis and kinetic characterization. To the best of our knowledge, this is the first example of isolating and characterizing a potent enzyme inhibitor from a partially purified crude natural product extract using a protein crystallographic approach. PMID:27498895
Gennis, L S
1976-01-01
A three-step procedure including affinity chromatography on NAD+-azobenzamidopropyl-Sepharose has been designed for the purification of yeast glyceraldehyde-3-phosphate dehydrogenase [D-glyceraldehyde-3-phosphate: NAD+ oxidoreductase (phosphorylating), EC 1.2.1.12] with maximized specific activity and maximized homogeneity with respect to affinity for the coenzyme, NAD+.Binding isotherms allow the analysis of cooperativity patterns that disclose both the average ligand affinity in the system and the distribution of ligands among the sites, only for systems with complete affinity homogeneity. The presence of affinity heterogeneity, resulting from multiple oligomeric species differing only in their affinity for coenzyme, gives rise to isotherms which falsely manifest apparent negative cooperativity. A method for distinguishing negative homotropic cooperativity from affinity heterogeneity is suggested. PMID:186779
Velocity ratio and its application to predicting velocities
Lee, Myung W.
2003-01-01
The velocity ratio of water-saturated sediment derived from the Biot-Gassmann theory depends mainly on the Biot coefficient?a property of dry rock?for consolidated sediments with porosity less than the critical porosity. With this theory, the shear moduli of dry sediments are the same as the shear moduli of water-saturated sediments. Because the velocity ratio depends on the Biot coefficient explicitly, Biot-Gassmann theory accurately predicts velocity ratios with respect to differential pressure for a given porosity. However, because the velocity ratio is weakly related to porosity, it is not appropriate to investigate the velocity ratio with respect to porosity (f). A new formulation based on the assumption that the velocity ratio is a function of (1?f)n yields a velocity ratio that depends on porosity, but not on the Biot coefficient explicitly. Unlike the Biot-Gassmann theory, the shear moduli of water-saturated sediments depend not only on the Biot coefficient but also on the pore fluid. This nonclassical behavior of the shear modulus of water-saturated sediment is speculated to be an effect of interaction between fluid and the solid matrix, resulting in softening or hardening of the rock frame and an effect of velocity dispersion owing to local fluid flow. The exponent n controls the degree of softening/hardening of the formation. Based on laboratory data measured near 1 MHz, this theory is extended to include the effect of differential pressure on the velocity ratio by making n a function of differential pressure and consolidation. However, the velocity dispersion and anisotropy are not included in the formulation.
Sodium Velocity Maps on Mercury
NASA Technical Reports Server (NTRS)
Potter, A. E.; Killen, R. M.
2011-01-01
The objective of the current work was to measure two-dimensional maps of sodium velocities on the Mercury surface and examine the maps for evidence of sources or sinks of sodium on the surface. The McMath-Pierce Solar Telescope and the Stellar Spectrograph were used to measure Mercury spectra that were sampled at 7 milliAngstrom intervals. Observations were made each day during the period October 5-9, 2010. The dawn terminator was in view during that time. The velocity shift of the centroid of the Mercury emission line was measured relative to the solar sodium Fraunhofer line corrected for radial velocity of the Earth. The difference between the observed and calculated velocity shift was taken to be the velocity vector of the sodium relative to Earth. For each position of the spectrograph slit, a line of velocities across the planet was measured. Then, the spectrograph slit was stepped over the surface of Mercury at 1 arc second intervals. The position of Mercury was stabilized by an adaptive optics system. The collection of lines were assembled into an images of surface reflection, sodium emission intensities, and Earthward velocities over the surface of Mercury. The velocity map shows patches of higher velocity in the southern hemisphere, suggesting the existence of sodium sources there. The peak earthward velocity occurs in the equatorial region, and extends to the terminator. Since this was a dawn terminator, this might be an indication of dawn evaporation of sodium. Leblanc et al. (2008) have published a velocity map that is similar.
Theoretical relationship between elastic wave velocity and electrical resistivity
NASA Astrophysics Data System (ADS)
Lee, Jong-Sub; Yoon, Hyung-Koo
2015-05-01
Elastic wave velocity and electrical resistivity have been commonly applied to estimate stratum structures and obtain subsurface soil design parameters. Both elastic wave velocity and electrical resistivity are related to the void ratio; the objective of this study is therefore to suggest a theoretical relationship between the two physical parameters. Gassmann theory and Archie's equation are applied to propose a new theoretical equation, which relates the compressional wave velocity to shear wave velocity and electrical resistivity. The piezo disk element (PDE) and bender element (BE) are used to measure the compressional and shear wave velocities, respectively. In addition, the electrical resistivity is obtained by using the electrical resistivity probe (ERP). The elastic wave velocity and electrical resistivity are recorded in several types of soils including sand, silty sand, silty clay, silt, and clay-sand mixture. The appropriate input parameters are determined based on the error norm in order to increase the reliability of the proposed relationship. The predicted compressional wave velocities from the shear wave velocity and electrical resistivity are similar to the measured compressional velocities. This study demonstrates that the new theoretical relationship may be effectively used to predict the unknown geophysical property from the measured values.
Measurement of neutrino masses from relative velocities.
Zhu, Hong-Ming; Pen, Ue-Li; Chen, Xuelei; Inman, Derek; Yu, Yu
2014-09-26
We present a new technique to measure neutrino masses using their flow field relative to dark matter. Present day streaming motions of neutrinos relative to dark matter and baryons are several hundred km/s, comparable with their thermal velocity dispersion. This results in a unique dipole anisotropic distortion of the matter-neutrino cross power spectrum, which is observable through the dipole distortion in the cross correlation of different galaxy populations. Such a dipole vanishes if not for this relative velocity and so it is a clean signature for neutrino mass. We estimate the size of this effect and find that current and future galaxy surveys may be sensitive to these signature distortions. PMID:25302878
High-velocity bipolar mass flow in the planetary nebula NGC 2392
Gieseking, F.; Becker, I.; Solf, J.
1985-08-01
Detailed spectroscopic observations of a high-velocity component in the velocity field of the Eskimo nebula, NGC 2392, are presented. It is interpreted as a jetlike multiknot bipolar mass flow with a velocity of nearly 200 km/s and a small angle of collimation less than 10 deg. Electron density, mass, kinetic energy, and power are estimated. 19 references.
Saphire, E.O.; Montero, M.; Menendez, A.; Houten, N.E.van; Irving, M.B.; Pantophlet, R.; Swick, M.B.; Parren, P.W.H.I.; Burton, D.R.; Scott, J.K.; Wilson, I.A.; /Scripps Res. Inst. /Simon Fraser U. /British Columbia U.
2007-07-13
The human antibody b12 recognizes a discontinuous epitope on gp120 and is one of the rare monoclonal antibodies that neutralize a broad range of primary human immunodeficiency virus type 1 (HIV-1) isolates. We previously reported the isolation of B2.1, a dimeric peptide that binds with high specificity to b12 and competes with gp120 for b12 antibody binding. Here, we show that the affinity of B2.1 was improved 60-fold over its synthetic-peptide counterpart by fusing it to the N terminus of a soluble protein. This affinity, which is within an order of magnitude of that of gp120, probably more closely reflects the affinity of the phage-borne peptide. The crystal structure of a complex between Fab of b12 and B2.1 was determined at 1.8 Angstrom resolution. The structural data allowed the differentiation of residues that form critical contacts with b12 from those required for maintenance of the antigenic structure of the peptide, and revealed that three contiguous residues mediate B2.1's critical contacts with b12. This single region of critical contact between the B2.1 peptide and the b12 paratope is unlikely to mimic the discontinuous key binding residues involved in the full b12 epitope for gp120, as previously identified by alanine scanning substitutions on the gp120 surface. These structural observations are supported by experiments that demonstrate that B2.1 is an ineffective immunogenic mimic of the b12 epitope on gp120. Indeed, an extensive series of immunizations with B2.1 in various forms failed to produce gp120 cross-reactive sera. The functional and structural data presented here, however, suggest that the mechanism by which b12 recognizes the two antigens is very different. Here, we present the first crystal structure of peptide bound to an antibody that was originally raised against a discontinuous protein epitope. Our results highlight the challenge of producing immunogens that mimic discontinuous protein epitopes, and the necessity of combining
NASA Technical Reports Server (NTRS)
Johnson, Dennis A. (Inventor)
1996-01-01
A laser doppler velocimeter uses frequency shifting of a laser beam to provide signal information for each velocity component. A composite electrical signal generated by a light detector is digitized and a processor produces a discrete Fourier transform based on the digitized electrical signal. The transform includes two peak frequencies corresponding to the two velocity components.
Instantaneous Velocity Using Photogate Timers
ERIC Educational Resources Information Center
Wolbeck, John
2010-01-01
Photogate timers are commonly used in physics laboratories to determine the velocity of a passing object. In this application a card attached to a moving object breaks the beam of the photogate timer providing the time for the card to pass. The length L of the passing card can then be divided by this time to yield the average velocity (or speed)…
Definition of Contravariant Velocity Components
NASA Technical Reports Server (NTRS)
Hung, Ching-Mao; Kwak, Dochan (Technical Monitor)
2002-01-01
This is an old issue in computational fluid dynamics (CFD). What is the so-called contravariant velocity or contravariant velocity component? In the article, we review the basics of tensor analysis and give the contravariant velocity component a rigorous explanation. For a given coordinate system, there exist two uniquely determined sets of base vector systems - one is the covariant and another is the contravariant base vector system. The two base vector systems are reciprocal. The so-called contravariant velocity component is really the contravariant component of a velocity vector for a time-independent coordinate system, or the contravariant component of a relative velocity between fluid and coordinates, for a time-dependent coordinate system. The contravariant velocity components are not physical quantities of the velocity vector. Their magnitudes, dimensions, and associated directions are controlled by their corresponding covariant base vectors. Several 2-D (two-dimensional) linear examples and 2-D mass-conservation equation are used to illustrate the details of expressing a vector with respect to the covariant and contravariant base vector systems, respectively.
ANALYSIS OF RADIAL VELOCITY DATA BY A NOVEL ADAPTIVE APPROACH
Babu, P.; Stoica, P.; Li, J.; Chen, Z.; Ge, J.
2010-02-15
In this paper, we introduce an estimation technique for analyzing radial velocity data commonly encountered in extrasolar planet detection. We discuss the Keplerian model for radial velocity data measurements and introduce a technique named the iterative adaptive approach (IAA) to estimate the three-dimensional spectrum (power versus eccentricity, orbital period and periastron passage time) of the radial velocity data. We then discuss different ways to regularize the IAA algorithm in the presence of noise and measurement errors. We also discuss briefly the computational aspects of the method and introduce a computationally efficient version of IAA. Finally, we establish the significance of the spectral peaks by using a relaxation maximum likelihood algorithm and a generalized likelihood ratio test. Numerical experiments are carried out on both simulated and real life data sets to evaluate the performance of our method. The real life data sets discussed are radial velocity measurements of the stars HD 63454, HD 208487, and GJ 876.
A MAGNETIC CALIBRATION OF PHOTOSPHERIC DOPPLER VELOCITIES
Welsch, Brian T.; Fisher, George H.; Sun, Xudong
2013-03-10
The zero point of measured photospheric Doppler shifts is uncertain for at least two reasons: instrumental variations (from, e.g., thermal drifts); and the convective blueshift, a known correlation between intensity and upflows. Accurate knowledge of the zero point is, however, useful for (1) improving estimates of the Poynting flux of magnetic energy across the photosphere, and (2) constraining processes underlying flux cancellation, the mutual apparent loss of magnetic flux in closely spaced, opposite-polarity magnetogram features. We present a method to absolutely calibrate line-of-sight (LOS) velocities in solar active regions (ARs) near disk center using three successive vector magnetograms and one Dopplergram coincident with the central magnetogram. It exploits the fact that Doppler shifts measured along polarity inversion lines (PILs) of the LOS magnetic field determine one component of the velocity perpendicular to the magnetic field, and optimizes consistency between changes in LOS flux near PILs and the transport of transverse magnetic flux by LOS velocities, assuming that ideal electric fields govern the magnetic evolution. Previous calibrations fitted the center-to-limb variation of Doppler velocities, but this approach cannot, by itself, account for residual convective shifts at the limb. We apply our method to vector magnetograms of AR 11158, observed by the Helioseismic and Magnetic Imager aboard the Solar Dynamics Observatory, and find clear evidence of offsets in the Doppler zero point in the range of 50-550 m s{sup -1}. In addition, we note that a simpler calibration can be determined from an LOS magnetogram and Dopplergram pair from the median Doppler velocity among all near-disk-center PIL pixels. We briefly discuss shortcomings in our initial implementation, and suggest ways to address these. In addition, as a step in our data reduction, we discuss the use of temporal continuity in the transverse magnetic field direction to correct apparently
Accuracy Assessment of Altimeter Derived Geostrophic Velocities
NASA Astrophysics Data System (ADS)
Leben, R. R.; Powell, B. S.; Born, G. H.; Guinasso, N. L.
2002-12-01
Along track sea surface height anomaly gradients are proportional to cross track geostrophic velocity anomalies allowing satellite altimetry to provide much needed satellite observations of changes in the geostrophic component of surface ocean currents. Often, surface height gradients are computed from altimeter data archives that have been corrected to give the most accurate absolute sea level, a practice that may unnecessarily increase the error in the cross track velocity anomalies and thereby require excessive smoothing to mitigate noise. Because differentiation along track acts as a high-pass filter, many of the path length corrections applied to altimeter data for absolute height accuracy are unnecessary for the corresponding gradient calculations. We report on a study to investigate appropriate altimetric corrections and processing techniques for improving geostrophic velocity accuracy. Accuracy is assessed by comparing cross track current measurements from two moorings placed along the descending TOPEX/POSEIDON ground track number 52 in the Gulf of Mexico to the corresponding altimeter velocity estimates. The buoys are deployed and maintained by the Texas Automated Buoy System (TABS) under Interagency Contracts with Texas A&M University. The buoys telemeter observations in near real-time via satellite to the TABS station located at the Geochemical and Environmental Research Group (GERG) at Texas A&M. Buoy M is located in shelf waters of 57 m depth with a second, Buoy N, 38 km away on the shelf break at 105 m depth. Buoy N has been operational since the beginning of 2002 and has a current meter at 2m depth providing in situ measurements of surface velocities coincident with Jason and TOPEX/POSEIDON altimeter over flights. This allows one of the first detailed comparisons of shallow water near surface current meter time series to coincident altimetry.
Spatial correlation of shear-wave velocity within San Francisco Bay Sediments
Thompson, E.M.; Baise, L.G.; Kayen, R.E.
2006-01-01
Sediment properties are spatially variable at all scales, and this variability at smaller scales influences high frequency ground motions. We show that surface shear-wave velocity is highly correlated within San Francisco Bay Area sediments using shear-wave velocity measurements from 210 seismic cone penetration tests. We use this correlation to estimate the surface sediment velocity structure using geostatistics. We find that the variance of the estimated shear-wave velocity is reduced using ordinary kriging, and that including this velocity structure in 2D ground motion simulations of a moderate sized earthquake improves the accuracy of the synthetics. Copyright ASCE 2006.
Effectively nonlocal metric-affine gravity
NASA Astrophysics Data System (ADS)
Golovnev, Alexey; Koivisto, Tomi; Sandstad, Marit
2016-03-01
In metric-affine theories of gravity such as the C-theories, the spacetime connection is associated to a metric that is nontrivially related to the physical metric. In this article, such theories are rewritten in terms of a single metric, and it is shown that they can be recast as effectively nonlocal gravity. With some assumptions, known ghost-free theories with nonsingular and cosmologically interesting properties may be recovered. Relations between different formulations are analyzed at both perturbative and nonperturbative levels, taking carefully into account subtleties with boundary conditions in the presence of integral operators in the action, and equivalences between theories related by nonlocal redefinitions of the fields are verified at the level of equations of motion. This suggests a possible geometrical interpretation of nonlocal gravity as an emergent property of non-Riemannian spacetime structure.
Affinity chromatography with an immobilized RNA enzyme.
Vioque, A; Altman, S
1986-01-01
M1 RNA, the catalytic subunit of Escherichia coli RNase P, has been covalently linked at its 3' terminus to agarose beads. Unlike M1 RNA, which is active in solution in the absence of the protein component (C5) of RNase P, the RNA linked to the beads is active only in the presence of C5 protein. Affinity chromatography of crude extracts of E. coli on a column prepared from the beads to which the RNA has been crosslinked results in the purification of C5 protein in a single step. The protein has been purified in this manner from cells that contain a plasmid, pINIIIR20, which includes the gene that codes for C5 protein. A 6-fold amplification of the expression of C5 protein is found in these cells after induction as compared to cells that do not harbor the plasmid. Images PMID:3526344
Wetting on rough self-affine surfaces
NASA Astrophysics Data System (ADS)
Palasantzas, George
1995-05-01
In this paper, we present a general investigation of the effective potential for complete wetting on self-affine rough surfaces. The roughness effect is investigated by means of the height-height correlation model in Fourier space ~(1+aξ2q2)-1-H. The parameters H and ξ are, respectively, the roughness exponent and the substrate in-plane correlation length. It is observed that the effect of H on the free interface profile is significant for ξ
High-affinity neuropeptide Y receptor antagonists.
Daniels, A J; Matthews, J E; Slepetis, R J; Jansen, M; Viveros, O H; Tadepalli, A; Harrington, W; Heyer, D; Landavazo, A; Leban, J J
1995-01-01
Neuropeptide Y (NPY) is one of the most abundant peptide transmitters in the mammalian brain. In the periphery it is costored and coreleased with norepinephrine from sympathetic nerve terminals. However, the physiological functions of this peptide remain unclear because of the absence of specific high-affinity receptor antagonists. Three potent NPY receptor antagonists were synthesized and tested for their biological activity in in vitro, ex vivo, and in vivo functional assays. We describe here the effects of these antagonists inhibiting specific radiolabeled NPY binding at Y1 and Y2 receptors and antagonizing the effects of NPY in human erythroleukemia cell intracellular calcium mobilization perfusion pressure in the isolated rat kidney, and mean arterial blood pressure in anesthetized rats. PMID:7568074
Evaluation system of negative electron affinity photocathode
NASA Astrophysics Data System (ADS)
Fu, Rongguo; Chang, Benkang; Qian, Yunsheng; Wang, Guihua; Zong, Zhiyuan
2001-10-01
This article first describes the background of the research and manufacture of evaluation system of Negative Electron Affinity photocathode. This article designs a set of super high vacuum system for activating NEA photocathode on the base of activation theory, the process of design and debugging is given. The system is composed of three parts: super high vacuum system for GaAs material activation, multi-meter testing system, surface analysis system. The system is used for on-line evaluation of activating of NEA photocathode. The technical parameters and structure of the evaluation system of NEA photocathode are given in the paper. The system is finished and experiments are made. At last the picture of the system is given.
Increased ductility in high velocity electromagnetic ring expansion
NASA Astrophysics Data System (ADS)
Altynova, Marina; Hu, Xiaoyu; Daehn, Glenn S.
1996-07-01
Thin rings have been rapidly expanded using large, transient magnetic fields to study the effect of deformation velocity on strains to failure of ductile metals. A classical electrodynamics analysis similar to one developed previously by Gourdin was employed to estimate sample velocities. Within expansion velocities studied (50 to 300 m/s), the experimental results show that ductility of Al 6061 and OFHC Cu increases monotonically with increasing velocity. In each case, sample strain at failure is almost twice as great at 300 m/s as in the static condition. Comparison to a one-dimensional rigid-viscoplastic dynamic finite element method analysis suggests that inertial effects are mainly responsible for enhanced ductility over a wide range of velocity.
Dye affinity cryogels for plasmid DNA purification.
Çimen, Duygu; Yılmaz, Fatma; Perçin, Işık; Türkmen, Deniz; Denizli, Adil
2015-11-01
The aim of this study is to prepare megaporous dye-affinity cryogel discs for the purification of plasmid DNA (pDNA) from bacterial lysate. Poly(hydroxyethyl methacrylate) [PHEMA] cryogel discs were produced by free radical polymerization initiated by N,N,N',N'-tetramethylene diamine (TEMED) and ammonium persulfate (APS) redox pair in an ice bath. Cibacron Blue F3GA was used as an affinity ligand (loading amount: 68.9μmol/g polymer). The amount of pDNA adsorbed onto the PHEMA-Cibacron Blue F3GA cryogel discs first increased and then reached a plateau value (i.e., 32.5mg/g cryogel) at 3.0mg/mL pDNA concentration. Compared with the PHEMA cryogel (0.11mg/g cryogel), the pDNA adsorption capacity of the PHEMA-Cibacron Blue F3GA cryogel (32.4mg/g polymer) was improved significantly due to the Cibacron Blue 3GA immobilization onto the polymeric matrix. pDNA adsorption amount decreased from 11.7mg/g to 1.1mg/g with the increasing of NaCl concentration. The maximum pDNA adsorption was achieved at 4°C. The overall recovery of pDNA was calculated as 90%. The PHEMA-Cibacron Blue F3GA cryogel discs could be used five times without decreasing the pDNA adsorption capacity significantly. The results show that the PHEMA-Cibacron Blue F3GA cryogel discs promise high selectivity for pDNA. PMID:26249596
Estimation of power in low velocity vertical axis wind turbine
NASA Astrophysics Data System (ADS)
Sampath, S. S.; Shetty, Sawan; Chithirai Pon Selvan, M.
2015-06-01
The present work involves in the construction of a vertical axis wind turbine and the determination of power. Various different types of turbine blades are considered and the optimum blade is selected. Mechanical components of the entire setup are built to obtain maximum rotation per minute. The mechanical energy is converted into the electrical energy by coupling coaxially between the shaft and the generator. This setup produces sufficient power for consumption of household purposes which is economic and easily available.
Ascent Velocity of Plasmoids Generated by Surface Discharges
NASA Astrophysics Data System (ADS)
Wenzel, Uwe
The ascent velocity of long-lived plasmoids generated under atmospheric conditions to simulate ball lightning was estimated in [Fussmann et al., Phys. Unserer Zeit 39, 246 (2008) and Jegorov et al., Tech. Phys. 53, 688 (2008): Refs. 1 and 2 in the text, respectively], using a rigid sphere model with poor agreement with the experiment. The plasmoids were, however, deformed. Much better agreement is obtained using the Davies and Taylor formula, which describes the ascent velocity of large spherical-cap bubbles.
Purification of glycolytic enzymes by using affinity-elution chromatography.
Scopes, R K
1977-01-01
1. A systematic procedure for the purification of enzymes by affinity-elution chromatography is described. Enzymes are adsorbed on a cation-exchanger, and eluted with ligands specific for the enzyme concerned. 2. All of the glycolytic and some related enzymes present in rabbit muscle can be purified by the affinity-elution technique. The pH range for adsorption and elution of each enzyme was found, and the effects of minor variations of conditions are described. 3. A description of experimental conditions suitable for affinity elution of each enzyme is given, together with special features relevant to each individual enzyme. 4. Theoretical considerations of affinity elution chromatography are discussed, including its limitations, advantages and disadvantages compared with affinity-adsorption chromatography. Possible developments are suggested to cover enzymes which because of their adsorption characteristics are not at present amenable to affinity-elution procedures. PMID:192194
Antibody-based affinity cryo-EM grid.
Yu, Guimei; Li, Kunpeng; Jiang, Wen
2016-05-01
The Affinity Grid technique combines sample purification and cryo-Electron Microscopy (cryo-EM) grid preparation into a single step. Several types of affinity surfaces, including functionalized lipids monolayers, streptavidin 2D crystals, and covalently functionalized carbon surfaces have been reported. More recently, we presented a new affinity cryo-EM approach, cryo-SPIEM, which applies the traditional Solid Phase Immune Electron Microscopy (SPIEM) technique to cryo-EM. This approach significantly simplifies the preparation of affinity grids and directly works with native macromolecular complexes without need of target modifications. With wide availability of high affinity and high specificity antibodies, the antibody-based affinity grid would enable cryo-EM studies of the native samples directly from cell cultures, targets of low abundance, and unstable or short-lived intermediate states.
Prediction of Neutral Salt Elution Profiles for Affinity Chromatography
NASA Astrophysics Data System (ADS)
Robinson, Jack B.; Strottmann, James M.; Stellwagen, Earle
1981-04-01
Neutral salts exhibit very marked differences as eluants of proteins from affinity columns. We observe: (i) that the relative potencies of neutral salts as eluants are independent of the protein or the affinity ligand in the systems studied, (ii) that the absolute salt concentration necessary to elute any given protein bound to the affinity matrix is proportional to the algebraic sum of a set of elution coefficients defined herein for the separate ions present in the solution, and (iii) that the proportionality between elution potency and elution coefficient is a function of the affinity of the protein for the immobilized ligand. Given the concentration of one neutral salt required for elution of a protein of interest from an affinity column, the elution capability of any neutral salt at any temperature can be quantitatively predicted for that protein. Accordingly, application and elution protocols for affinity chromatography can be designed to optimize the yield and fold purification of proteins.
Lower bound on the electroweak wall velocity from hydrodynamic instability
Mégevand, Ariel; Membiela, Federico Agustín; Sánchez, Alejandro D.
2015-03-27
The subsonic expansion of bubbles in a strongly first-order electroweak phase transition is a convenient scenario for electroweak baryogenesis. For most extensions of the Standard Model, stationary subsonic solutions (i.e., deflagrations) exist for the propagation of phase transition fronts. However, deflagrations are known to be hydrodynamically unstable for wall velocities below a certain critical value. We calculate this critical velocity for several extensions of the Standard Model and compare with an estimation of the wall velocity. In general, we find a region in parameter space which gives stable deflagrations as well as favorable conditions for electroweak baryogenesis.
Lower bound on the electroweak wall velocity from hydrodynamic instability
Mégevand, Ariel; Membiela, Federico Agustín; Sánchez, Alejandro D. E-mail: membiela@mdp.edu.ar
2015-03-01
The subsonic expansion of bubbles in a strongly first-order electroweak phase transition is a convenient scenario for electroweak baryogenesis. For most extensions of the Standard Model, stationary subsonic solutions (i.e., deflagrations) exist for the propagation of phase transition fronts. However, deflagrations are known to be hydrodynamically unstable for wall velocities below a certain critical value. We calculate this critical velocity for several extensions of the Standard Model and compare with an estimation of the wall velocity. In general, we find a region in parameter space which gives stable deflagrations as well as favorable conditions for electroweak baryogenesis.
The effect of dilatancy on velocity anisotropy in Westerly granite
NASA Technical Reports Server (NTRS)
Soga, N.; Mizutani, H.; Spetzler, H.; Martin, R. J., III
1978-01-01
Jacketed samples of Westerly granite were fractured at confining pressures up to 1 kbar, and compressional and horizontally as well as vertically polarized shear velocities were measured in orthogonal directions perpendicular to the compression axis. Changes occurring with increased strain are described, and the velocity data were analyzed by application of the Anderson et al (1974) approach. Observed and calculated velocities are found to be in good agreement, and the degree of dilatancy was determined from the differences between the strains measured perpendicularly to the compression axis and the estimated elastic strains in those directions.
Measurements of groundwater velocity in discrete rock fractures.
Novakowski, Kent; Bickerton, Greg; Lapcevic, Pat; Voralek, John; Ross, Nathalie
2006-01-01
Estimating groundwater velocity in fracture networks using a Darcy or cubic law calculation is complicated by the wide distribution of fracture aperture often found in these systems and by the difficulty in measuring hydraulic head in discrete fracture features. Although difficult to conduct in a fractured rock setting, the point dilution method can be utilized to collect direct measurements of groundwater velocity in individual fractures. To compare measured against calculated velocities, more than 100 point dilution experiments were conducted within a 35 x 35 m area of a single fracture and in discrete fracture features within a fracture network at a larger scale. The dilution experiments were conducted by isolating a fracture feature in a borehole, measuring the hydraulic aperture, and measuring the decay of an injected tracer due to the advective groundwater flux across the fracture. Groundwater velocity was estimated using the hydraulic aperture and the rate of decay of the injected tracer. Estimates of the local hydraulic gradient were calculated via the cubic law using the velocity estimate and the hydraulic aperture. The results of the tests conducted in the single fracture show variable (1 to 33 m/day) but on average higher velocities in comparison to that measured during a natural gradient tracer experiment conducted previously (in which the effects of matrix diffusion were accounted for) and to that which would be calculated using the cubic law. Based on these results, it was determined that the best estimate of the average groundwater velocity, at the scale of the measurement area used for the cubic law calculations, could only be obtained using the largest apertures in the aperture distribution. Variability of the velocity measurements was also observed over time. Increases in velocity were attributed to the effect of rainfall although concurrent increases in hydraulic gradient were not detected (likely within the tolerance of the measuring devices
On the photoelectron velocity-map imaging of lutetium monoxide anion LuO{sup −}
Liu, Zhiling; Xie, Hua; Qin, Zhengbo; Cong, Ran; Wu, Xia; Tang, Zichao Fan, Hongjun; Li, Quanjiang
2014-01-21
We report a combined photoelectron velocity-map imaging spectroscopy and density functional theory investigation on lutetium monoxide anion. Transition between the X {sup 1}Σ{sup +} anion electronic ground state and the neutral X {sup 2}Σ{sup +} electronic ground state is observed. Vibrationally resolved spectra were obtained at four different photon energies, providing a wealth of spectroscopic information for the electronic ground states of the anionic lutetium monoxide and corresponding neutral species. Franck-Condon simulations of the ground-state transition are performed to assign vibrational structure in the spectra and to assist in identifying the observed spectral bands. The electronic ground state of LuO{sup −} is found to have a vibrational frequency of 743 ± 10 cm{sup −1} and an equilibrium bond length of 1.841 Å. The electron affinity of LuO is measured to be 1.624 ± 0.002 eV. The fundamental frequency of ground-state LuO is estimated to be 839 ± 10 cm{sup −1}.
On the photoelectron velocity-map imaging of lutetium monoxide anion LuO(-).
Liu, Zhiling; Xie, Hua; Li, Quanjiang; Qin, Zhengbo; Cong, Ran; Wu, Xia; Tang, Zichao; Fan, Hongjun
2014-01-21
We report a combined photoelectron velocity-map imaging spectroscopy and density functional theory investigation on lutetium monoxide anion. Transition between the X (1)Σ(+) anion electronic ground state and the neutral X (2)Σ(+) electronic ground state is observed. Vibrationally resolved spectra were obtained at four different photon energies, providing a wealth of spectroscopic information for the electronic ground states of the anionic lutetium monoxide and corresponding neutral species. Franck-Condon simulations of the ground-state transition are performed to assign vibrational structure in the spectra and to assist in identifying the observed spectral bands. The electronic ground state of LuO(-) is found to have a vibrational frequency of 743 ± 10 cm(-1) and an equilibrium bond length of 1.841 Å. The electron affinity of LuO is measured to be 1.624 ± 0.002 eV. The fundamental frequency of ground-state LuO is estimated to be 839 ± 10 cm(-1).
ESTIMATING URBAN WET-WEATHER POLLUTANT LOADING
This paper presents procedures for estimating pollutant loads in urban watersheds emanating from wet-weather flow discharge. Equations for pollutant loading estimates will focus on the effects of wastewater characteristics, sewer flow carrying velocity, and sewer-solids depositi...
ERIC Educational Resources Information Center
Hart, Vincent G.
1981-01-01
Two examples are given of ways traffic engineers estimate traffic flow. The first, Floating Car Method, involves some basic ideas and the notion of relative velocity. The second, Maximum Traffic Flow, is viewed to involve simple applications of calculus. The material provides insight into specialized applications of mathematics. (MP)
Affinity chromatography for purification of two urokinases from human urine.
Takahashi, R; Akiba, K; Koike, M; Noguchi, T; Ezure, Y
2000-05-26
A new affinity chromatography (hydrophobic-mediated affinity chromatography), which was characterized by the matrix having both affinity site to urokinase and hydrophobic site, was established for the purification of urokinase from human urine. The hydrophobic affinity matrix (tentatively named PAS in the text) was prepared by immobilizing 6-aminocaproic acid on Sepharose CL-6B, followed by a coupling p-aminobenzamidine to a part of the hydrophobic site on the matrix. The PAS matrix was applied to the purification of urokinase from human urine, and high- and low-molecular weight pure urokinases were efficiently obtained in high yield by the present method. PMID:10892585
Detection properties of phase velocities with SPAC arrays including structural boundary
NASA Astrophysics Data System (ADS)
Shiraishi, H.; Asanuma, H.
2013-12-01
Microtremor survey method (MSM) is a technique to estimate subsurface velocity structures by inverting phase velocities of the surface waves in the microtremors. All the existing inversion techniques for the MSM have been deduced under an implicit assumption of horizontal velocity structure. Velocity structures in shallow sediment are, however, practically very inhomogeneous, and the assumption may not be suitable in many cases of the MSM applications. Therefore we have examined the behavior of estimated phase velocities with the SPAC technique when arrays intersect a structural boundary, because errors in velocity estimation in the MSM for inhomogeneous velocity cases have not been elucidated. An example of theoretical analysis is shown in Figs, where phase differences of two sensors which placed across a structural boundary have been analytically expressed and then the SPAC technique have been performed using complex coherence functions (Shiraishi et. al., 2006). Fig.1 shows the geometry of a SPAC array along with a velocity boundary. Here, we assumed different horizontal velocity model for right and left sides. Fig.2 shows estimated phase velocities for various locations of structural boundaries. This result shows that the estimated velocities gradually vary according to the location of boundaries and it seems that the phase velocities determined by the occupying rate of each structure along the length of the array. Therefore, in the case of the boundary placed inside the center of the array, the estimated velocities would be adopted intermediate value of the two different structures and the error is maximized. We have also examined these properties with three dimensional simulations and have confirmed similar features. Furthermore, we have examined some classifying measures of discontinuous structures within the array. We believe that these results will contribute to derive a new estimation technique for the MSM of covering discontinuous or gradient structures.
Horns as particle velocity amplifiers.
Donskoy, Dimitri M; Cray, Benjamin A
2011-11-01
Preliminary measurements and numerical predictions reveal that simple, and relatively small, horns generate remarkable amplification of acoustic particle velocity. For example, below 2 kHz, a 2.5 cm conical horn has a uniform velocity amplification ratio (throat-to-mouth) factor of approximately 3, or, in terms of a decibel level, 9.5 dB. It is shown that the velocity amplification factor depends on the horn's mouth-to-throat ratio as well as, though to a lesser degree, the horn's flare rate. A double horn configuration provides limited additional gain, approximately an increase of up to 25%.
Dendritic Growth Velocities in Microgravity
NASA Technical Reports Server (NTRS)
Glicksman, M. E.; Koss, M. B.; Winsa, E. A.
1994-01-01
We measured dendritic tip velocities in pure succinonitrile (SCN) in microgravity. using a sequence of telemetered binary images sent to Earth from the Space Shuttle Columbia (STS-62). Growth velocities were measured as a function of the supercooling over the range 0.05-1.5 K. Microgravity observations show that buoyancy-induced convection alters the growth kinetics of SCN dendrites at supercooling as high as 1.3 K. Also, the dendrite velocity data measured under microgravity agree well with the Ivantsov paraboloidal diffusion solution when coupled to a scaling constant of sigma(sup *) = 0.0157.
Slutzki, Michal; Barak, Yoav; Reshef, Dan; Schueler-Furman, Ora; Lamed, Raphael; Bayer, Edward A
2012-01-01
The cellulosome is a large bacterial extracellular multienzyme complex able to degrade crystalline cellulosic substrates. The complex contains catalytic and noncatalytic subunits, interconnected by high-affinity cohesin-dockerin interactions. In this chapter, we introduce an optimized method for comparative binding among different cohesins or cohesin mutants to the dockerin partner. This assay offers advantages over other methods (such as ELISA, cELIA, SPR, and ITC) for particularly high-affinity binding interactions. In this approach, the high-affinity interaction of interest occurs in the liquid phase during the equilibrated binding step, whereas the interaction with the immobilized phase is used only for detection of the unbound dockerins that remain in the solution phase. Once equilibrium conditions are reached, the change in free energy of binding (ΔΔG(binding)), as well as the affinity constant of mutants, can be estimated against the known affinity constant of the wild-type interaction. In light of the above, we propose this method as a preferred alternative for the relative quantification of high-affinity protein interactions. PMID:22608739
Doppler velocity measurements from large and small arteries of mice
Reddy, Anilkumar K.; Madala, Sridhar; Entman, Mark L.; Michael, Lloyd H.; Taffet, George E.
2011-01-01
With the growth of genetic engineering, mice have become increasingly common as models of human diseases, and this has stimulated the development of techniques to assess the murine cardiovascular system. Our group has developed nonimaging and dedicated Doppler techniques for measuring blood velocity in the large and small peripheral arteries of anesthetized mice. We translated technology originally designed for human vessels for use in smaller mouse vessels at higher heart rates by using higher ultrasonic frequencies, smaller transducers, and higher-speed signal processing. With these methods one can measure cardiac filling and ejection velocities, velocity pulse arrival times for determining pulse wave velocity, peripheral blood velocity and vessel wall motion waveforms, jet velocities for the calculation of the pressure drop across stenoses, and left main coronary velocity for the estimation of coronary flow reserve. These noninvasive methods are convenient and easy to apply, but care must be taken in interpreting measurements due to Doppler sample volume size and angle of incidence. Doppler methods have been used to characterize and evaluate numerous cardiovascular phenotypes in mice and have been particularly useful in evaluating the cardiac and vascular remodeling that occur following transverse aortic constriction. Although duplex ultrasonic echo-Doppler instruments are being applied to mice, dedicated Doppler systems are more suitable for some applications. The magnitudes and waveforms of blood velocities from both cardiac and peripheral sites are similar in mice and humans, such that much of what is learned using Doppler technology in mice may be translated back to humans. PMID:21572013
Fine velocity structures collisional dissipation in plasmas
NASA Astrophysics Data System (ADS)
Pezzi, Oreste; Valentini, Francesco; Veltri, Pierluigi
2016-04-01
In a weakly collisional plasma, such as the solar wind, collisions are usually considered far too weak to produce any significant effect on the plasma dynamics [1]. However, the estimation of collisionality is often based on the restrictive assumption that the particle velocity distribution function (VDF) shape is close to Maxwellian [2]. On the other hand, in situ spacecraft measurements in the solar wind [3], as well as kinetic numerical experiments [4], indicate that marked non-Maxwellian features develop in the three-dimensional VDFs, (temperature anisotropies, generation of particle beams, ring-like modulations etc.) as a result of the kinetic turbulent cascade of energy towards short spatial scales. Therefore, since collisional effects are proportional to the velocity gradients of the VDF, the collisionless hypothesis may fail locally in velocity space. Here, the existence of several characteristic times during the collisional relaxation of fine velocity structures is investigated by means of Eulerian numerical simulations of a spatially homogeneous force-free weakly collisional plasma. The effect of smoothing out velocity gradients on the evolution of global quantities, such as temperature and entropy, is discussed, suggesting that plasma collisionality can increase locally due to the velocity space deformation of the particle velocity distribution. In particular, by means of Eulerian simulations of collisional relaxation of a spatially homogeneous force-free plasma, in which collisions among particles of the same species are modeled through the complete Landau operator, we show that the system entropy growth occurs over several time scales, inversely proportional to the steepness of the velocity gradients in the VDF. We report clear evidences that fine velocity structures are dissipated by collisions in a time much shorter than global non-Maxwellian features, like, for example, temperature anisotropies. Moreover we indicate that, if small-scale structures
Complex Affine Toda Theories and Soliton Solutions
NASA Astrophysics Data System (ADS)
Zhu, Zhiqing
1995-01-01
Toda field theories (TFT's) constitute a large class of integrable (1 + 1)-dimensional field theories that are relativistically invariant: included are conformal field theories and integrable deformations away from conformality. Because they are soluble, for example, by the inverse scattering method, and because they are related to many other areas of field theory, they have been studied extensively in recent years. Hirota's method is a straightforward procedure to obtain soliton solutions to non-linear integrable equations. In Hirota's method, one first writes the nonlinear equations in Hirota's bilinear form, and then expands the so called tau-functions as a power series in an arbitrary parameter. The power series terminates at some finite order, thus the solutions obtained are exact. For an N-soliton solution, the number of terms in the expansion grows exponentially with N, making direct calculation of N-soliton solutions difficult. We extend Hirota's one -parameter expansion to an N-parameter expansion. In the new expansion series, many terms are identical to those in the (N - 1)-soliton solutions, and new terms grow only linearly with N. Furthermore, we note that the expansion must terminate at some finite order, thus the vanishing of higher order terms can be used as constraints on these new terms. It turns out that these constraints can be used to determine the new terms completely. We used this extended Hirota's method to find N-soliton solutions for complex affine TFT's based on a simply-laced Kac-Moody algebra. Soliton solutions for non-simply-laced complex ATFT's can be obtained for those of simply-laced complex ATFT's by folding or twisting. Even though some soliton solutions have already been obtained for complex ATFT's by various methods, the physical implications of these solutions have not yet been thoroughly discussed. There are infinitely many distinct topological solitons in any given complex affine Toda field theory and most of them have complex