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Sample records for africanum west african

  1. Differences between TB cases infected with M. africanum, West-African type 2, relative to Euro-American M. tuberculosis- an update

    PubMed Central

    de Jong, Bouke C; Adetifa, Ifedayo; Walther, Brigitte; Hill, Philip C; Antonio, Martin; Ota, Martin; Adegbola, Richard A

    2009-01-01

    M. africanum is a common cause of human pulmonary TB in West Africa. We previously described phenotypic differences between M. africanum and M. tuberculosis among 290 patients. In the present analysis we compared 692 TB patients infected with the two most common lineages within the M. tuberculosis complex found in the Gambia, namely M. africanum West African type 2 (39% prevalence) and Euro American M. tuberculosis (55% prevalence). We identified additional phenotypic differences between infections with these two organisms. M. africanum patients were more likely to be of older age and HIV infected. In addition, they had worse disease on chest x-ray, despite complaining of cough for equal duration, and were more likely severely malnourished. In this cohort the prevalence of M. africanum did not change significantly over a seven year period. PMID:20002176

  2. Draft Genome Sequence of a Mycobacterium africanum Clinical Isolate from Antioquia, Colombia

    PubMed Central

    Hurtado, U. A.; Solano, J. S.; Rodriguez, A.; Rouzaud, F.

    2016-01-01

    Mycobacterium africanum is a member of the Mycobacterium tuberculosis complex. Most commonly found in West African countries, it has scarcely been described in South America. Here, we report the first genome sequence of a Colombian M. africanum clinical isolate. It is composed of 4,493,502 bp, with 4,069 genes. PMID:27257203

  3. Phenotypic and Genotypic Characterization of Mycobacterium africanum Isolates from West Africa

    PubMed Central

    Frothingham, Richard; Strickland, Percy L.; Bretzel, Gisela; Ramaswamy, Srinivas; Musser, James M.; Williams, Diana L.

    1999-01-01

    The Mycobacterium tuberculosis complex includes M. tuberculosis, M. bovis, M. africanum, and M. microti. Most clinical isolates are M. tuberculosis or M. bovis. These species can be distinguished by phenotypes and genotypes. However, there is no simple definition of M. africanum, and some authors question the validity of this species. We analyzed 17 human isolates from Sierra Leone, identified as M. africanum by biochemical and growth characteristics. We sequenced polymorphic genes and intergenic regions. We amplified DNA from six loci with variable numbers of tandem repeats (VNTRs) and determined the exact number of repeats at each locus in each strain. All M. africanum isolates had the ancestral CTG Leu at katG codon 463. Drug-resistant M. africanum isolates had katG and rpoB mutations similar to those found in drug-resistant M. bovis and M. tuberculosis. Fourteen Sierra Leone M. africanum isolates (designated group A) had katG codon 203 ACC Thr, also found in M. africanumT (the T indicates type strain) from Senegal. Group A isolates clustered with M. africanumT by VNTR analysis. Three M. africanum isolates (group B) had katG codon 203 ACT Thr, found in M. tuberculosisT, and clustered with M. tuberculosisT by VNTR analysis. Phenotypic identification of M. africanum yielded a heterogeneous collection of strains. Genotypic analyses identified a cluster (M. africanum group A) which included M. africanumT and was distinct from the rest of the M. tuberculosis complex. Future studies of M. africanum should include both phenotypic and genotypic analyses. PMID:10325347

  4. Impact of the Mycobaterium africanum West Africa 2 Lineage on TB Diagnostics in West Africa: Decreased Sensitivity of Rapid Identification Tests in The Gambia

    PubMed Central

    Ofori-Anyinam, Boatema; Kanuteh, Fatoumatta; Okoi, Catherine; Dolganov, Gregory; Schoolnik, Gary; Secka, Ousman; Antonio, Martin; de Jong, Bouke C.; Gehre, Florian

    2016-01-01

    Background MPT64 rapid speciation tests are increasingly being used in diagnosis of tuberculosis (TB). Mycobacterium africanum West Africa 2 (Maf 2) remains an important cause of TB in West Africa and causes one third of disease in The Gambia. Since the introduction of MPT64 antigen tests, a higher than expected rate of suspected non-tuberculous mycobacteria (NTM) was seen among AFB smear positive TB suspects, which led us to prospectively assess sensitivity of the MPT64 antigen test in our setting. Methodology/Principal Findings We compared the abundance of mRNA encoded by the mpt64 gene in sputa of patients with untreated pulmonary TB caused by Maf 2 and Mycobacterium tuberculosis (Mtb). Subsequently, prospectively collected sputum samples from presumptive TB patients were inoculated in the BACTEC MGIT 960 System. One hundred and seventy-three acid fast bacilli (AFB)-positive and blood agar negative MGIT cultures were included in the study. Cultures were tested on the day of MGIT positivity with the BD MGIT TBc Identification Test. A random set of positives and all negatives were additionally tested with the SD Bioline Ag MPT64 Rapid. MPT64 negative cultures were further incubated at 37°C and retested until positive. Bacteria were spoligotyped and assigned to different lineages. Maf 2 isolates were 2.52-fold less likely to produce a positive test result and sensitivity ranged from 78.4% to 84.3% at the beginning and end of the recommended 10 day testing window, respectively. There was no significant difference between the tests. We further showed that the decreased rapid test sensitivity was attributable to variations in mycobacterial growth behavior and the smear grades of the patient. Conclusions/Significance In areas where Maf 2 is endemic MPT64 tests should be cautiously used and MPT64 negative results confirmed by a second technique, such as nucleic acid amplification tests, to avoid their misclassification as NTMs. PMID:27387550

  5. West African crude production diversifies

    SciTech Connect

    Aalund, L.

    1983-06-01

    Nigeria, with its seven crude-oil export streams, dominated West African production and accounted for over 70% of the depressed 1.8 million b/d output from the region last year. However, during the 1970s a flurry of new producing fields, primarily off the African coast, diversified production among a number of countries and touched off a wave of oil activity. The Journal takes a close look at the quality of West African oil in this installment of assays on world export crudes. This issue covers, in alphabetical order, Bonny Light (Nigeria) to Espoir (Ivory Coast). A following issue will wrap up West Africa by presenting assays on crudes from Forcados Blend (Nigeria) to Zaire Crude (Zaire).

  6. Improvisation in West African Musics.

    ERIC Educational Resources Information Center

    Locke, David

    1980-01-01

    Discussed is music of the sub-Sahara. Vocal, instrumental, and dance drumming from the Sudan Desert, the North Coast, East Horn, Central and West Africa, and contrapuntal yodeling of Pygmies is described. For African musicians, the ability to improvise, and creativity, are gifts from God. Includes selected readings and recordings. (KC)

  7. A West African Link

    ERIC Educational Resources Information Center

    Cook, Angela; Davies, Penny

    2003-01-01

    The authors visited Ghana in West Africa to strengthen a link established the previous year as part of Channel 4's "On the Line" project. The initial link established in 1999/2000 was between an all-age special school in Enfield and a similar school in Accra. Over the course of that year further partnerships were created between five UK schools…

  8. An Introduction to West African Literature.

    ERIC Educational Resources Information Center

    Taiwo, Oladele

    Intended to provide help for those interested in studying West African literature, this book is divided into three parts. Part One provides background information: the various African oral traditions are discussed, related to the way of life of the people, and examined for the extent to which they form the basis of present West African literary…

  9. Tuberculosis Caused by Mycobacterium africanum, United States, 2004–2013

    PubMed Central

    Bloss, Emily; Heilig, Charles M.; Click, Eleanor S.

    2016-01-01

    Mycobacterium africanum is endemic to West Africa and causes tuberculosis (TB). We reviewed reported cases of TB in the United States during 2004–2013 that had lineage assigned by genotype (spoligotype and mycobacterial interspersed repetitive unit variable number tandem repeats). M. africanum caused 315 (0.4%) of 73,290 TB cases with lineage assigned by genotype. TB caused by M. africanum was associated more with persons from West Africa (adjusted odds ratio [aOR] 253.8, 95% CI 59.9–1,076.1) and US-born black persons (aOR 5.7, 95% CI 1.2–25.9) than with US-born white persons. TB caused by M. africanum did not show differences in clinical characteristics when compared with TB caused by M. tuberculosis. Clustered cases defined as >2 cases in a county with identical 24-locus mycobacterial interspersed repetitive unit genotypes, were less likely for M. africanum (aOR 0.1, 95% CI 0.1–0.4), which suggests that M. africanum is not commonly transmitted in the United States. PMID:26886258

  10. Children Ask Questions about West African Art.

    ERIC Educational Resources Information Center

    Abercrombie, Denice; Cochran, Mathilda; Mims, Margaret

    1997-01-01

    Presents a collection of questions that fifth-grade students asked about African artwork and answers provided by staff from the Museum of Fine Arts in Houston, Texas. Observes that students' interest in important visual aspects of the art creates lead-ins to more detailed discussions of West African art and culture. (DSK)

  11. West African Folktales [and] Instructor's Manual.

    ERIC Educational Resources Information Center

    Gale, Steven H.

    Traditionally, an important function of folktales in West Africa has been to educate, as the older generation imparts knowledge to younger members of the family, tribe, societal unit, or ethnic group both informally in everyday life and more formally within the context of the bush schools. This anthology of West African folk literature offers more…

  12. Intimate Partner Violence among West African Immigrants

    PubMed Central

    AKINSULURE-SMITH, ADEYINKA M.; CHU, TRACY; KEATLEY, EVA; RASMUSSEN, ANDREW

    2013-01-01

    Although the number of African immigrants arriving to the United States has increased significantly, there has been little investigation regarding their experiences of intimate partner violence or coping strategies. This study used focus groups and individual interviews to explore intimate partner violence among 32 heterosexual West African immigrants. Results suggest that although cultural expectations influence their coping strategies, West African–born men and women face different realities, with women reporting multiple instances of abuse and a sense of frustration with the existing options for assistance. Although participants discussed multilevel support structures within the immediate West African community to address intimate partner violence, all of these options maintained a gender hierarchy, leaving women dissatisfied. Challenges and barriers to partner violence resolution and coping strategies are identified. Results are examined in terms of their implications for addressing the needs of this underserved population. Implications for future research and services are discussed and highlighted. PMID:23730146

  13. Heat flow from the West African shield

    SciTech Connect

    Brigaud, F.; Lucazeau, F.; Ly, S.; Sauvage, J.F.

    1985-09-01

    The heat flow over Precambrian shields is generally lower than over other continental provinces. Previous observations at 9 sites of the West African shield have shown that heat flow ranges from 20 mW m/sup -2/ in Niger to 38-42 mW m/sup -2/ in Liberia, Ghana and Nigeria. Since some of these values are lower than expected for Precambrian shields, it is important to find out whether or not they are representative of the entire shield before trying to derive its thermal structure. In this paper, we present new heat flow determinations from seven sites of the West African shield. These indicate that the surface heat flow is comparable with that of other Precambrian shields in the world.

  14. Complicating Culturally Relevant Pedagogy: Unpacking West African Immigrants' Cultural Identities

    ERIC Educational Resources Information Center

    Allen, Keisha McIntosh; Jackson, Iesha; Knight, Michelle G.

    2012-01-01

    This study presents findings from a case study of 18 second- and 1.5-generation West African immigrants. We draw upon notions of elusive culture and indigenous knowledges to highlight participants' complex cultural identities and respond to anti-immigration discourses through positioning West African immigrant students as assets in American…

  15. Experimental characterization of West African Newcastle disease virus

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Four West African strains and one South African strain of virulent Newcastle disease virus (NDV) were characterized through a two-phase experiment. Strains investigated were Burkina Faso/2415-580/2008, Nigeria/228-7/2006, Niger/1377/2006, and Goose/South Africa/08100426/2008. Phylogenetic analysis s...

  16. Immunogenic Mycobacterium africanum strains associated with ongoing transmission in The Gambia.

    PubMed

    Gehre, Florian; Antonio, Martin; Otu, Jacob K; Sallah, Neneh; Secka, Oumie; Faal, Tutty; Owiafe, Patrick; Sutherland, Jayne S; Adetifa, Ifedayo M; Ota, Martin O; Kampmann, Beate; Corrah, Tumani; de Jong, Bouke C

    2013-10-01

    In West Africa, Mycobacterium tuberculosis strains co-circulate with M. africanum, and both pathogens cause pulmonary tuberculosis in humans. Given recent findings that M. tuberculosis T-cell epitopes are hyperconserved, we hypothesized that more immunogenic strains have increased capacity to spread within the human host population. We investigated the relationship between the composition of the mycobacterial population in The Gambia, as measured by spoligotype analysis, and the immunogenicity of these strains as measured by purified protein derivative-induced interferon-γ release in ELISPOT assays of peripheral blood mononuclear cells. We found a positive correlation between strains with superior spreading capacity and their relative immunogenicity. Although our observation is true for M. tuberculosis and M. africanum strains, the association was especially pronounced in 1 M. africanum sublineage, characterized by spoligotype shared international type 181, which is responsible for 20% of all tuberculosis cases in the region and therefore poses a major public health threat in The Gambia.

  17. Relationships among obesity, inflammation, and insulin resistance in African Americans and West Africans.

    PubMed

    Doumatey, Ayo P; Lashley, Kerrie S; Huang, Hanxia; Zhou, Jie; Chen, Guanjie; Amoah, Albert; Agyenim-Boateng, Kofi; Oli, Johnnie; Fasanmade, Olufemi; Adebamowo, Clement A; Adeyemo, Adebowale A; Rotimi, Charles N

    2010-03-01

    Several research studies in different populations indicate that inflammation may be the link between obesity and insulin resistance (IR). However, this relationship has not been adequately explored among African Americans, an ethnic group with disproportionately high rates of obesity and IR. In this study, we conducted a comparative study of the relationship among adiposity, inflammation, and IR in African Americans and West Africans, the ancestral source population for African Americans. The associations between obesity markers (BMI and waist-to-hip ratio (WHR)), inflammatory markers (high-sensitivity C-reactive protein (hsCRP), haptoglobin, interleukin (IL)-6, and tumor necrosis factor (TNF)-alpha), and IR (homeostasis model assessment of insulin resistance (HOMA(IR))) were evaluated in 247 West Africans and 315 African Americans. In average, African Americans were heavier than the West Africans (by an average of 1.6 BMI units for women and 3 BMI units for men). Plasma hsCRP, haptoglobin, and IL-6 (but not TNF-alpha level) were higher in African Americans than in West Africans. In both populations, BMI was associated with markers of inflammation and with HOMA(IR), and these associations remained significant after adjusting for sex and age. However, the pattern of associations between measured inflammatory markers and IR was different between the two groups. In West Africans, hsCRP was the only inflammatory marker associated with IR. In contrast, hsCRP, haptoglobin, and IL-6 were all associated with IR in African Americans. Interestingly, none of the associations between markers of inflammation and IR remained significant after adjusting for BMI. This finding suggests that in African Americans, the relationship between inflammatory markers and IR is mediated by adiposity.

  18. Mitogenome revealed multiple postdomestication genetic mixtures of West African sheep.

    PubMed

    Brahi, O H D; Xiang, H; Chen, X; Farougou, S; Zhao, X

    2015-10-01

    Notable diversity observed within African ovine breeds makes them of great interests, but limited studies on genetic origins and domestications remain poorly understood. Here, we investigate the evolutionary status of West African native breeds, Djallonke and Sahelian sheep using mitogenome sequencing. Compared with other ovine mitogenome sequences, West African sheep were revealed a Eurasian origin, and the initially tamed sheep breeds in West Africa have been genetically mixed with each other and mixed with European breeds. Worldwide domestic sheep is deemed the Eurasian origin and migrated west to Europe and Africa and east to the Far East, in which dispersed and received selection for acclimation to autochthonic environment independently and ultimately evolved into different native breeds, respectively. Our results contribute to the comprehensive understanding of the domestic sheep origin and reveal multiple postdomestication genetic amelioration processes.

  19. Assessment of undiscovered oil and gas resources of the West African Costal Province, West Africa

    USGS Publications Warehouse

    Brownfield, Michael E.; Charpentier, Ronald R.; Schenk, Christopher J.; Klett, Timothy R.; Cook, Troy A.; Pollastro, Richard M.

    2011-01-01

    The West African Coastal Province along the west African coastline recently was assessed for undiscovered, technically recoverable oil, natural gas, and natural gas liquids resources as part of the U.S. Geological Survey's USGS World Oil and Gas Assessment. Using a geology-based assessment methodology, the USGS estimated mean volumes of 3.2 billion barrels of oil, 23.63 trillion cubic feet of natural gas, and 721 million barrels of natural gas liquids.

  20. Y Chromosome Lineages in Men of West African Descent

    PubMed Central

    Keita, Shomarka O. Y.; Kittles, Rick A.

    2012-01-01

    The early African experience in the Americas is marked by the transatlantic slave trade from ∼1619 to 1850 and the rise of the plantation system. The origins of enslaved Africans were largely dependent on European preferences as well as the availability of potential laborers within Africa. Rice production was a key industry of many colonial South Carolina low country plantations. Accordingly, rice plantations owners within South Carolina often requested enslaved Africans from the so-called “Grain Coast” of western Africa (Senegal to Sierra Leone). Studies on the African origins of the enslaved within other regions of the Americas have been limited. To address the issue of origins of people of African descent within the Americas and understand more about the genetic heterogeneity present within Africa and the African Diaspora, we typed Y chromosome specific markers in 1,319 men consisting of 508 west and central Africans (from 12 populations), 188 Caribbeans (from 2 islands), 532 African Americans (AAs from Washington, DC and Columbia, SC), and 91 European Americans. Principal component and admixture analyses provide support for significant Grain Coast ancestry among African American men in South Carolina. AA men from DC and the Caribbean showed a closer affinity to populations from the Bight of Biafra. Furthermore, 30–40% of the paternal lineages in African descent populations in the Americas are of European ancestry. Diverse west African ancestries and sex-biased gene flow from EAs has contributed greatly to the genetic heterogeneity of African populations throughout the Americas and has significant implications for gene mapping efforts in these populations. PMID:22295064

  1. Ion Transport in Hydrodictyon africanum

    PubMed Central

    Raven, J. A.

    1967-01-01

    The concentrations of K, Na, and Cl in the cytoplasm and vacuole, the tracer fluxes of these ions into and out of the cenocyte, and the electrical potential difference between bathing solution and vacuole and cytoplasm, have been measured in Hydrodictyon africanum. If the ions were acted on solely by passive electrochemical forces, a net efflux of K and Cl and a net influx of Na would be expected. Tracer fluxes indicate a net influx of K and Cl and efflux of Na in the light; these net fluxes are consequently active, with an obligate link to metabolism. The effects of darkness and low temperature indicate that most of the tracer K and Cl influx and Na efflux are linked to metabolism, while the corresponding tracer fluxes in the direction of the free energy gradient are not. Ouabain specifically inhibits the metabolically linked portions of tracer K influx and Na efflux. Alterations in the external K concentration have similar effects on metabolically mediated K influx and Na efflux. It would appear that K influx and Na efflux are linked, at least in the light. PMID:6034760

  2. Black English Near its Roots: The Transplanted West African Creoles.

    ERIC Educational Resources Information Center

    Birmingham, John C., Jr.

    It seems highly likely that many of the features of Black American English can be traced back to the Afro-Portuguese Creole dialects that sprang up in the fifteenth century in Portuguese slave camps along the West African coast, particularly in the Gulf of Guinea area, the area of greatest concentration of activity during the slave trade. This…

  3. West African warming: Investigating Temperature Trends and their relation between Precipitation Trends over West African Sahel.

    NASA Astrophysics Data System (ADS)

    LY, M., Jr.

    2014-12-01

    It is now admitted that the West African region faces a lot of constraints due to the comprehensiveness of the high climate variability and potential climate change. This is mainly due to the lack of a large number of datasets and long-term records as summarized in the in the IPCC reports. This paper aims to provide improved knowledge and evidence on current and future climate conditions, for better manage climate variability over seasons and from year to year and strengthen the capacity to adapt to future climate change. In this regards, we analyse the evolution of some extreme temperature and precipitation indices over a large area of West Africa. Prior results show a general warming trend at individual stations throughout the region during the period from 1960 to 2010, namely negative trends in the number of cool nights, and positive trends in the number of warm days and length of warm spells. Trends in rainfall-related indices are not as uniform as the ones in temperatures, rather they display marked multi-decadal variability, as expected. To refine analyses of temperature variations and their relation to precipitation we investigated on cluster analysis aimed at distinguishing different sub-regions, such as continental and coastal, and relevant seasons, such as wet, dry/cold and dry warm. This will contribute to significantly lower uncertainties by developing better and more tailored temperature and precipitation trends to inform the user communities on climate related risks, as well as enhance their resilience to food insecurity and other climate related disasters.

  4. Assessing the contributions of East African and West Pacific warming to the 2014 boreal spring East African drought

    USGS Publications Warehouse

    Funk, Christopher C.; Shukla, Shraddhanand; Hoell, Andrew; Livneh, Ben

    2015-01-01

    Anthropogenic warming contributed to the 2014 East African drought by increasing East African and west Pacific temperatures, and increasing the gradient between standardized western and central Pacific SST causing reduced rainfall, evapotranspiration, and soil moisture.

  5. Whole Genome Sequencing of Mycobacterium africanum Strains from Mali Provides Insights into the Mechanisms of Geographic Restriction

    PubMed Central

    Maiga, Mamoudou; Abeel, Thomas; Shea, Terrance; Desjardins, Christopher A.; Diarra, Bassirou; Baya, Bocar; Sanogo, Moumine; Diallo, Souleymane; Earl, Ashlee M.; Bishai, William R.

    2016-01-01

    Background Mycobacterium africanum, made up of lineages 5 and 6 within the Mycobacterium tuberculosis complex (MTC), causes up to half of all tuberculosis cases in West Africa, but is rarely found outside of this region. The reasons for this geographical restriction remain unknown. Possible reasons include a geographically restricted animal reservoir, a unique preference for hosts of West African ethnicity, and an inability to compete with other lineages outside of West Africa. These latter two hypotheses could be caused by loss of fitness or altered interactions with the host immune system. Methodology/Principal Findings We sequenced 92 MTC clinical isolates from Mali, including two lineage 5 and 24 lineage 6 strains. Our genome sequencing assembly, alignment, phylogeny and average nucleotide identity analyses enabled us to identify features that typify lineages 5 and 6 and made clear that these lineages do not constitute a distinct species within the MTC. We found that in Mali, lineage 6 and lineage 4 strains have similar levels of diversity and evolve drug resistance through similar mechanisms. In the process, we identified a putative novel streptomycin resistance mutation. In addition, we found evidence of person-to-person transmission of lineage 6 isolates and showed that lineage 6 is not enriched for mutations in virulence-associated genes. Conclusions This is the largest collection of lineage 5 and 6 whole genome sequences to date, and our assembly and alignment data provide valuable insights into what distinguishes these lineages from other MTC lineages. Lineages 5 and 6 do not appear to be geographically restricted due to an inability to transmit between West African hosts or to an elevated number of mutations in virulence-associated genes. However, lineage-specific mutations, such as mutations in cell wall structure, secretion systems and cofactor biosynthesis, provide alternative mechanisms that may lead to host specificity. PMID:26751217

  6. Phylogenetic Relationships of Southern African West Nile Virus Isolates

    PubMed Central

    Grobbelaar, Antoinette A.; Leman, Patricia A.; Anthony, Fiona S.; Gibson, Georgina V.F.; Swanepoel, Robert

    2002-01-01

    Phylogenetic relationships were examined for 29 southern African West Nile virus (formal name West Nile virus [WNV]) isolates from various sources in four countries from 1958 to 2001. In addition sequence data were retrieved from GenBank for another 23 WNV isolates and Kunjin and Japanese encephalitis viruses. All isolates belonged to two lineages. Lineage 1 isolates were from central and North Africa, Europe, Israel, and North America; lineage 2 isolates were from central and southern Africa and Madagascar. No strict correlation existed between grouping and source of virus isolate, pathogenicity, geographic distribution, or year of isolation. Some southern African isolates have been associated with encephalitis in a human, a horse, and a dog and with fatal hepatitis in a human and death of an ostrich chick. PMID:12141968

  7. Exploring female genital cutting among west African immigrants.

    PubMed

    Akinsulure-Smith, Adeyinka M

    2014-06-01

    Although many African women immigrate to the United States from countries with high prevalence rates for female genital cutting (FGC), there has been limited research exploring the incidence and impact of FGC among this growing immigrant population. This pilot study sought to examine the experiences of FGC among West African immigrant women in the US. Of the 23 participants, 7 reported a history of FGC, with Muslim participants reporting significantly higher rates of FGC than Christians (Fisher's Exact = .045). Most of the women who had experienced FGC were from Sierra Leone (Fisher's Exact = .027). Limitations of the study are discussed along with suggestions for future research aimed at understanding the impact of FGC, reducing the prevalence and demand for FGC among African immigrant women and improving the health and quality of life of women who have undergone the procedure.

  8. Factors influencing the migration of West African health professionals

    PubMed Central

    Lowe, Mat; Chen, Duan-Rung

    2016-01-01

    Introduction The West African health sector is characterized by a human resource base lacking in numbers and specialized skills. Among the contributory factors to this lack of human resource for health workforce include but not limited to the migration of health professionals. Methods This cross-sectional survey targeted 118 young professionals who have participated in the Young Professional Internship Program (YPIP) of the West African Health Organization (WAHO), from (2005-2013). It inquired about their socio-demographic characteristics associated with migration and reasons for going to their preferred or most likely destinations through online survey. Results Of the 118 young professionals, 100 responded to the online survey, of which (28%) have migrated and (72%) did not migrate. Migration was more common among males and those (age≤31 years old), single with high dependency level and no previous work experience. Having a medical profession and being posted to urban or semi-urban area was also associated with their emigration. Their most important reasons for going to preferred or most likely destinations were to have fair level of workload, job promotion and limited occupational risks. Conclusion This finding suggests that the migration of health professionals is situation dependent, mediated by basic socio-demographic variables and work related conditions. These issues have implications for curbing the brain drain potential of health professionals in the West African health sector. PMID:27800092

  9. Back to Africa: Second Chances for the Children of West African Immigrants

    ERIC Educational Resources Information Center

    Bledsoe, Caroline H.; Sow, Papa

    2011-01-01

    This paper examines the phenomenon of West African parents living in Europe and North America who send their older children back home: from places of high immigrant aspiration to those of hardship and privation. Drawing on a project on West African immigration to Europe and on previous field studies in Africa, we conclude that West African…

  10. Astronomy as Practiced in the West African City of Timbuktu

    NASA Astrophysics Data System (ADS)

    Medupe, Thebe Rodney

    Islam was introduced to West Africa over a millennium ago as a result of trade with North Africa and other parts of the Middle East. Islamic scholarship thrived in the city of Timbuktu in the fifteenth and sixteenth centuries. During this time West African scholars studied and taught mathematics, Quranic studies, and astronomy among other subjects. Until recently, the detail of what astronomy was known and practiced was not known. As an example of the content of material taught in the madrassas in West Africa, I present an outline of the content of two manuscripts written in the seventeenth century by Timbuktu scholars Muḥammad (or Aḥmad) b. Muḥammad Baghayu‛u b. Muḥammad Kūrdu and Abū l-‛Abbās Aḥmad b. al-Ḥājj R-mām-y-n al-Tuwātī al-Ghallāwī.

  11. West Indian Ocean variability and East African fish catch.

    PubMed

    Jury, M; McClanahan, T; Maina, J

    2010-08-01

    We describe marine climate variability off the east coast of Africa in the context of fish catch statistics for Tanzania and Kenya. The time series exhibits quasi-decadal cycles over the period 1964-2007. Fish catch is up when sea surface temperature (SST) and atmospheric humidity are below normal in the tropical West Indian Ocean. This pattern relates to an ocean Rossby wave in one phase of its east-west oscillation. Coastal-scale analyses indicate that northward currents and uplift on the shelf edge enhance productivity of East African shelf waters. Some of the changes are regulated by the south equatorial current that swings northward from Madagascar. The weather is drier and a salty layer develops in high catch years. While the large-scale West Indian Ocean has some impact on East African fish catch, coastal dynamics play a more significant role. Climatic changes are reviewed using 200 years of past and projected data. The observed warming trend continues to increase such that predicted SST may reach 30 degrees C by 2100 while SW monsoon winds gradually increase, according to a coupled general circulation model simulation with a gradual doubling of CO(2). PMID:20471674

  12. Prevalence of Glaucoma in an Urban West African Population

    PubMed Central

    Budenz, Donald L.; Barton, Keith; Whiteside-de Vos, Julia; Schiffman, Joyce; Bandi, Jagadeesh; Nolan, Winifred; Herndon, Leon; Kim, Hanna; Hay-Smith, Graham; Tielsch, James M.

    2014-01-01

    Importance Multiple studies have found an increased prevalence, younger age at onset, and more severe course of glaucoma in people of African descent, but these findings are based on studies conducted outside Africa. Objective To determine the prevalence of glaucoma in an urban West African population of adults. Design and Setting A population-based, cross-sectional study of adults 40 years and older conducted from September 1, 2006, through December 31, 2008, from 5 communities in Tema, Ghana. Participants Participants from randomly selected clusters underwent a screening examination that consisted of visual acuity, frequency doubling perimetry, applanation tonometry, and optic disc photography. Participants who failed any of these tests were referred for complete examination, including gonioscopy, standard automated perimetry, and stereoscopic optic disc photography. Results A total of 6806 eligible participants were identified, and 5603 (82.3%) were enrolled in the study. The field examination referred 1869 participants (33.3%) to the clinic examination, and 1538 (82.2%) came for complete examination. A total of 362 participants were identified as having glaucoma of any type and category. Primary open-angle glaucoma was the underlying diagnosis in 342 participants (94.5%). The prevalence of primary open-angle glaucoma was 6.8% overall, increasing from 3.7% among those 40 to 49 years old to 14.6% among those 80 years and older, and was higher in men than in women in all age groups, with an overall male-female prevalence ratio of 1.5. Of the participants with glaucoma, 9 (2.5%) were blind using World Health Organization criteria, and only 12 (3.3%) were aware that they had glaucoma. Conclusions and Relevance The prevalence of glaucoma is higher in this urban West African population than in previous studies of people of East or South African and of non-African descent. Strategies to identify affected persons and effectively manage the burden of glaucoma are needed

  13. Will Elephants Soon Disappear from West African Savannahs?

    PubMed Central

    Bouché, Philippe; Douglas-Hamilton, Iain; Wittemyer, George; Nianogo, Aimé J.; Doucet, Jean-Louis; Lejeune, Philippe; Vermeulen, Cédric

    2011-01-01

    Precipitous declines in Africa's native fauna and flora are recognized, but few comprehensive records of these changes have been compiled. Here, we present population trends for African elephants in the 6,213,000 km2 Sudano-Sahelian range of West and Central Africa assessed through the analysis of aerial and ground surveys conducted over the past 4 decades. These surveys are focused on the best protected areas in the region, and therefore represent the best case scenario for the northern savanna elephants. A minimum of 7,745 elephants currently inhabit the entire region, representing a minimum decline of 50% from estimates four decades ago for these protected areas. Most of the historic range is now devoid of elephants and, therefore, was not surveyed. Of the 23 surveyed elephant populations, half are estimated to number less than 200 individuals. Historically, most populations numbering less than 200 individuals in the region were extirpated within a few decades. Declines differed by region, with Central African populations experiencing much higher declines (−76%) than those in West Africa (−33%). As a result, elephants in West Africa now account for 86% of the total surveyed. Range wide, two refuge zones retain elephants, one in West and the other in Central Africa. These zones are separated by a large distance (∼900 km) of high density human land use, suggesting connectivity between the regions is permanently cut. Within each zone, however, sporadic contacts between populations remain. Retaining such connectivity should be a high priority for conservation of elephants in this region. Specific corridors designed to reduce the isolation of the surveyed populations are proposed. The strong commitment of governments, effective law enforcement to control the illegal ivory trade and the involvement of local communities and private partners are all critical to securing the future of elephants inhabiting Africa's northern savannas. PMID:21731620

  14. Will elephants soon disappear from West African savannahs?

    PubMed

    Bouché, Philippe; Douglas-Hamilton, Iain; Wittemyer, George; Nianogo, Aimé J; Doucet, Jean-Louis; Lejeune, Philippe; Vermeulen, Cédric

    2011-01-01

    Precipitous declines in Africa's native fauna and flora are recognized, but few comprehensive records of these changes have been compiled. Here, we present population trends for African elephants in the 6,213,000 km² Sudano-Sahelian range of West and Central Africa assessed through the analysis of aerial and ground surveys conducted over the past 4 decades. These surveys are focused on the best protected areas in the region, and therefore represent the best case scenario for the northern savanna elephants. A minimum of 7,745 elephants currently inhabit the entire region, representing a minimum decline of 50% from estimates four decades ago for these protected areas. Most of the historic range is now devoid of elephants and, therefore, was not surveyed. Of the 23 surveyed elephant populations, half are estimated to number less than 200 individuals. Historically, most populations numbering less than 200 individuals in the region were extirpated within a few decades. Declines differed by region, with Central African populations experiencing much higher declines (-76%) than those in West Africa (-33%). As a result, elephants in West Africa now account for 86% of the total surveyed. Range wide, two refuge zones retain elephants, one in West and the other in Central Africa. These zones are separated by a large distance (∼900 km) of high density human land use, suggesting connectivity between the regions is permanently cut. Within each zone, however, sporadic contacts between populations remain. Retaining such connectivity should be a high priority for conservation of elephants in this region. Specific corridors designed to reduce the isolation of the surveyed populations are proposed. The strong commitment of governments, effective law enforcement to control the illegal ivory trade and the involvement of local communities and private partners are all critical to securing the future of elephants inhabiting Africa's northern savannas.

  15. The TG/HDL-C ratio does not predict insulin resistance in overweight women of African descent: a study of South African, African American and West African women.

    PubMed

    Knight, Michael G; Goedecke, Julia H; Ricks, Madia; Evans, Juliet; Levitt, Naomi S; Tulloch-Reid, Marshall K; Sumner, Anne E

    2011-01-01

    Women of African descent have a high prevalence of diseases caused by insulin resistance. To positively impact cardiometabolic health in Black women, effective screening tests for insulin resistance must be identified. Recently, the TG/HDL-C ratio has been recommended as a tool to predict insulin resistance in overweight people. While the ratio predicts insulin resistance in White women, it is ineffective in African American women. As there are no data for African women, we tested the ability of the TG/HDL-C ratio to predict insulin resistance in Black women from South Africa, West Africa and the United States. For comparison, the ratio was also tested in White women from South Africa. Participants were 801 women (157 Black South African, 382 African American, 119 West African, 143 White South African, age 36 +/- 9y [mean +/- SD]). Standardized scores were created from log-transformed homeostasis model assessment-insulin resistance values from each population. Participants in the upper third of their population distribution were classified as insulin-resistant. To predict insulin resistance by the TC/HDL-C ratio, area under the receiver operating characteristic (AUC-ROC) curve was used and criteria were: 0.50 for no discrimination and > or = 0.70 for acceptable. Seventy-one percent of the Black women were overweight vs 51% of White women (P<.01). In overweight White women, AUC-ROC curve for prediction of insulin resistance by TG/HDL-C was 0.76 +/- 0.06, but below the 0.70 threshold in each group of overweight Black women (Black South African: 0.64 +/- 0.06, African American: 0.66 +/- 0.03, and West African: 0.63 +/- 0.07). Therefore, TG/HDL-C does not predict insulin resistance in overweight African American women and this investigation extends that finding to overweight Black South African and West African women. Resources to identify effective markers of insulin resistance are needed to improve cardiometabolic health in women of African descent.

  16. Future of West African Monsoon in A Warming Climate

    NASA Astrophysics Data System (ADS)

    Raj, Jerry; Kunhu Bangalath, Hamza; Stenchikov, Georgiy

    2016-04-01

    West Africa is the home of more than 300 million people whose agriculture based economy highly relies on West African Monsoon (WAM), which produces a mean annual rainfall of 150 - 2,500 mm and variability and change of which have devastating impact on the local population. The observed widespread drought in West Africa during the 1970s and 1980s was the most significant drought at regional scale during the twentieth century. In this study, a high resolution AGCM, High Resolution Atmospheric Model (HiRAM), is used to study the effects of anthropogenic greenhouse warming on WAM. HiRAM is developed at GFDL based on AM2 and employs a cubed-sphere finite volume dynamical core and uses shallow convective scheme (for moist convection and stratiform cloudiness) instead of deep convective parameterization. Future projections are done using two representative concentration pathways, RCP 4.5 and RCP 8.5 from 2007 to 2050 at C360 (~25 km) resolution. Both RCP 4.5 and RCP 8.5 scenarios predict warming over West Africa during boreal summer, especially over Western Sahara. Also, both scenarios predict southward shift in WAM rainfall pattern and drying over Southern Sahara, while RCP 8.5 predicts enhanced rainfall over Gulf of Guinea. The intensification of rainfall over tropical latitudes is caused by increased low level winds due to warm SST over Gulf of Guinea.

  17. Do West African thunderstorms predict the intensity of Atlantic hurricanes?

    NASA Astrophysics Data System (ADS)

    Price, Colin; Reicher, Naama; Yair, Yoav

    2015-04-01

    Since 85% of all major Atlantic hurricanes originate as thunderstorm clusters in equatorial Africa, we have investigated the connection between these African thunderstorms and the consequent development of these disturbances into tropical storms. We have analyzed Meteosat infrared cloud top temperature data to determine the areal coverage of cold cloud tops over a 6 year period from 2005 to 2010. In addition, hurricane statistics from the same period (intensity, date of generation, location, and maximum winds) were obtained from the National Hurricane Center database. We first show that the areal coverage of cold clouds (with brightness temperatures Tb < -50°C) in tropical Africa is a good indicator of the monthly number of African Easterly Waves (AEWs) leaving the west coast of tropical Africa. Furthermore, the AEWs that develop into tropical storms have a significantly larger area covered by cold cloud tops compared with nondeveloping waves. Finally, we show that on a storm-by-storm basis, the cold cloud coverage in West Africa is positively correlated (r = 0.57) with the accumulated cyclone energy of the future tropical cyclones that develop out of these waves.

  18. Do West African Thunderstorms Predict the Intensity of Atlantic Hurricanes?

    NASA Astrophysics Data System (ADS)

    Price, Colin; Reicher, Naama; Yair, Yoav

    2015-04-01

    Since 85% of all major Atlantic hurricanes originate as thunderstorm clusters in equatorial Africa, we have investigated the connection between these African thunderstorms and the consequent development of these disturbances into tropical storms. We have analyzed METEOSAT infrared cloud-top temperature data to determine the areal coverage of cold cloud tops over a six year period from 2005-2010. In addition, hurricane statistics from the same period (intensity, date of generation, location, maximum winds) were obtained from the National Hurricane Center (NHC) data base. We first show that the areal coverage of cold clouds (with brightness temperatures Tb<-50oC) in tropical Africa is a good indicator of the monthly number of African Easterly Waves (AEWs) leaving the west coast of tropical Africa. Furthermore, the AEWs that develop into tropical storms have a significantly larger area covered by cold cloud tops compared with non-developing waves. Finally, we show that on a storm-by-storm basis, the cold cloud coverage in West Africa is positively correlated (r=0.57) with the accumulated cyclone energy (ACE) of the future tropical cyclones that develop out of these waves.

  19. English as a Second Language: An Educational Overview for Multicultural and Bilingual West African Students.

    ERIC Educational Resources Information Center

    Ubadigbo, Fidelis N.

    This paper describes cultural and educational characteristics of West African countries that may have implications for West Africans studying and learning English in the United States. Countries discussed include Nigeria, Ghana, Sierra Leone, Benin, Niger, Gambia, Senegal, Cote d'Ivoire, and Mali. The structures of the systems of elementary,…

  20. Spatial air pollution modelling for a West-African town.

    PubMed

    Gebreab, Sirak Zenebe; Vienneau, Danielle; Feigenwinter, Christian; Bâ, Hâmpaté; Cissé, Guéladio; Tsai, Ming-Yi

    2015-01-01

    Land use regression (LUR) modelling is a common approach used in European and Northern American epidemiological studies to assess urban and traffic related air pollution exposures. Studies applying LUR in Africa are lacking. A need exists to understand if this approach holds for an African setting, where urban features, pollutant exposures and data availability differ considerably from other continents. We developed a parsimonious regression model based on 48-hour nitrogen dioxide (NO2) concentrations measured at 40 sites in Kaédi, a medium sized West-African town, and variables generated in a geographic information system (GIS). Road variables and settlement land use characteristics were found to be important predictors of 48-hour NO2 concentration in the model. About 68% of concentration variability in the town was explained by the model. The model was internally validated by leave-one-out cross-validation and it was found to perform moderately well. Furthermore, its parameters were robust to sampling variation. We applied the model at 100 m pixels to create a map describing the broad spatial pattern of NO2 across Kaédi. In this research, we demonstrated the potential for LUR as a valid, cost-effective approach for air pollution modelling and mapping in an African town. If the methodology were to be adopted by environmental and public health authorities in these regions, it could provide a quick assessment of the local air pollution burden and potentially support air pollution policies and guidelines. PMID:26618306

  1. Monogeneans of West African Cichlid Fish: Evolution and Cophylogenetic Interactions

    PubMed Central

    Mendlová, Monika; Desdevises, Yves; Civáňová, Kristína; Pariselle, Antoine; Šimková, Andrea

    2012-01-01

    The goals of this paper were to investigate phylogenetic and evolutionary patterns of cichlid fish from West Africa and their Cichlidogyrus and Scutogyrus monogenean parasites, to uncover the presence of host-parasite cospeciation and to assess the level of morphological adaptation in parasites. This required the following steps, each one representing specific objectives of this paper: (1) to build phylogenetic trees for Cichlidogyrus and Scutogyrus species based on ribosomal DNA sequences, (2) to investigate phylogenetic relationships within West African cichlid fish based on the analysis of mitochondrial cytochrome b DNA sequences, (3) to investigate host-parasite cophylogenetic history to gain clues on parasite speciation process, and (4) to investigate the link between the morphology of the attachment apparatus and parasite phylogeny. Phylogenetic analyses supported the monophyletic origin of the Cichlidogyrus/Scutogyrus group, and suggested that Cichlidogyrus is polyphyletic and that Scutogyrus is monophyletic. The phylogeny of Cichlidae supported the separation of mouthbrooders and substrate-brooders and is consistent with the hypothesis that the mouthbrooding behavior of Oreochromis and Sarotherodon evolved from substrate-brooding behavior. The mapping of morphological characters of the haptor onto the parasite phylogenetic tree suggests that the attachment organ has evolved from a very simple form to a more complex one. The cophylogenetic analyses indicated a significant fit between trees using distance-based tests, but no significant cospeciation signal using tree-based tests, suggesting the presence of parasite duplications and host switches on related host species. This shed some light on the diversification process of Cichlidogyrus species parasitizing West African cichlids. PMID:22662139

  2. Regional analysis of convective systems during the West African monsoon

    NASA Astrophysics Data System (ADS)

    Guy, Bradley Nicholas

    The West African monsoon (WAM) occurs during the boreal summer and is responsible for a majority of precipitation in the northern portion of West Africa. A distinct shift of precipitation, often driven by large propagating mesoscale convective systems, is indicated from satellite observations. Excepting the coarser satellite observations, sparse data across the continent has prevented understanding of mesoscale variability of these important systems. The interaction between synoptic and mesoscale features appears to be an important part of the WAM system. Without an understanding of the mesoscale properties of precipitating systems, improved understanding of the feedback mechanism between spatial scales cannot be attained. Convective and microphysical characteristics of West African convective systems are explored using various observational data sets. Focus is directed toward meso -alpha and -beta scale convective systems to improve our understanding of characteristics at this spatial scale and contextualize their interaction with the larger-scale. Ground-based radar observations at three distinct geographical locations in West Africa along a common latitudinal band (Niamey, Niger [continental], Kawsara, Senegal [coastal], and Praia, Republic of Cape Verde [maritime]) are analyzed to determine convective system characteristics in each domain during a 29 day period in 2006. Ancillary datasets provided by the African Monsoon Multidisciplinary Analyses (AMMA) and NASA-AMMA (NAMMA) field campaigns are also used to place the radar observations in context. Results show that the total precipitation is dominated by propagating mesoscale convective systems. Convective characteristics vary according to environmental properties, such as vertical shear, CAPE, and the degree of synoptic forcing. Data are bifurcated based on the presence or absence of African easterly waves. In general, African easterly waves appear to enhance mesoscale convective system strength

  3. Rehydration characteristics of dehydrated West African pepper (Piper guineense) leaves.

    PubMed

    Okpala, Laura C; Ekechi, Constance A

    2014-11-01

    The rehydration characteristics of dehydrated West African pepper leaves were investigated at hydration temperatures of 28, 60, 70, and 80°C. Four treatments were given to the leaves: blanched and sun dried, unblanched and sun dried, blanched and shade dried, and unblanched and shade dried. The hydration process of the dehydrated leaves was adequately described by the Peleg's equation. As the hydration temperature increased from 28 to 70°C, there was a significant decrease in the Peleg's constant K 1, while for most of the leaves the Peleg's constant K 2 varied with temperature. Rehydration ratio values ranged from 3.75 in blanched shade dried leaves to 4.26 in unblanched sun dried leaves with the unblanched leaves generally exhibiting higher ratios than the blanched leaves.

  4. The West African International Summer School for Young Astronomers

    NASA Astrophysics Data System (ADS)

    Strubbe, Linda; Okere, Bonaventure I.; Chibueze, James; Lepo, Kelly; White, Heidi; Zhang, Jielai; Izuikedinachi Okoh, Daniel; Reid, Michael; Hunter, Lisa; EKEOMA Opara, Fidelis

    2015-08-01

    In October 2013 over 75 undergraduate science students and teachers from Nigeria and Ghana attended the week-long West African International Summer School for Young Astronomers. We expect an even broader audience for the second offering of the school (to be held July 2015), supported by a grant from the OAD (TF1). These schools are organized by a collaboration of astronomers from the University of Toronto, the University of Nigeria, and the Nigerian National Space Research and Development Agency. We design and lead activities that teach astronomy content, promote students' self-identity as scientists, and encourage students to think critically and figure out solutions themselves. Equally important, we design intertwined evaluation strategies to assess the effectiveness of our programs. We will describe the broader context for developing astronomy in West Africa, the inquiry-based and active learning techniques used in the schools, and results from the qualitative and quantitative evaluations of student performance. We will also describe longer-term plans for future schools, supporting our alumni, and building a sustainable partnership between North American and Nigerian universities.

  5. Noma: experiences with a microvascular approach under West African conditions.

    PubMed

    Giessler, Goetz A; Schmidt, Andreas B

    2003-09-15

    Noma (cancrum oris) is a serious ulcerating disease that generally begins in the gingival sulcus of children. One of the main areas of prevalence today is West Africa. If noma is survived, it results in disfiguring midfacial defects and intense scarring. Oral incompetence is often combined with trismus resulting from scar formation or bony fusion between the maxilla and the mandible. Reconstructive approaches with pedicled flaps from the head or shoulder area for closure of the outer defects have been prone to donor-site complications or have not properly addressed the trismus, leading to high recurrence rates. During three West African Interplast missions, a single-stage procedure was developed for reconstruction of the inner and outer linings of the oral, nasal, and paranasal cavities, with restoration of jaw function. The procedure consists of radical scar excision, placement of an external distractor for mouth opening, and primary closure of the defect with a folded free parascapular flap for full-thickness coverage. Twenty-three patients with various noma-related defects were treated with this procedure; two cases are described in detail. This combined treatment can be a safe successful procedure for patients with noma, especially those with severe soft-tissue destruction and profound trismus, even under demanding surgical conditions.

  6. Critical Postcolonial Dance Pedagogy: The Relevance of West African Dance Education in the United States

    ERIC Educational Resources Information Center

    Cruz Banks, Ojeya

    2010-01-01

    This dance ethnography examines work conducted by the Dambe Project--a nonprofit organization that specializes in African performing arts education and mentorship. The study focuses on the implications of the organization's dance pedagogy in light of its postcolonial context and the importance of West African dance education in the United States.…

  7. Cold War and Colonial Conflicts in British West African Adult Education, 1947-1953.

    ERIC Educational Resources Information Center

    Fieldhouse, Roger

    1984-01-01

    Adult education was introduced by the British into West Africa after World War II. However, the Oxford intellectuals put in charge of the adult education program offered an African-centered education that frequently offered more support to the progressive views of the African independence movements than to the colonialists' conservative policies.…

  8. Evaluation of West African Monsoon Processes and Feedbacks: Second West African Monsoon Modeling and Evaluation Project Experiment (WAMME II)

    NASA Astrophysics Data System (ADS)

    Xue, Y.; Lau, W. K.; Boone, A. A.; Seidou Sanda, I.; Thiaw, W. M.; Druyan, L.; Team, W.

    2013-12-01

    Despite recent progress in understanding of the West African monsoon (WAM), there are still many unanswered questions regarding to the impact of external forcings: oceans, land, and aerosols, on WAM variability, especially their roles in the Sahel drought. The West African Monsoon Modeling and Evaluation (WAMME) is a project comprised of both general circulation models (GCMs) and regional climate models (RCMs) with the objective to collectively provide best estimation of the relative importance of all those external forcing on WAM on seasonal to multi-decadal time scales. WAMME research activities are closely coordinated with those of AMMA, involving many African institutions. Observational evidence has shown strong decadal climate variabilities in the Sahel from the 1950s to the 2000s, not only in precipitation, but also in SST, vegetation cover, land use and land cover changes (LULCC), and aerosols. In WAMME-2, multi-model intercomparison experiments are designed to test how seasonal and decadal variabilities of WAM precipitation are associated with these forcings, and assess their relative contributions in producing/amplifying the WAM seasonal and decadal climate variability. The sensitivity of the WAM variability to those external forcings is also examined. The WAMME-2 strategy is to apply observational data-based anomaly forcing of SST, land surface and aerosols, i.e., "idealized but realistic" forcing, in GCM and RCM simulations with the specific purpose of estimating the relative impacts of each forcing and feedback mechanisms. In the SST experiment, in addition to the global SST effect, each ocean's role is also evaluated. The preliminary results from most GCMs consistently indicate that SST has a maximum impact on the WAM decadal variability compared with other forcings, and that the effect of the Pacific Ocean is most dominant. The models, however, differ in producing other oceans' contribution. Moreover, the models with specified maximum SST forcing are

  9. Mothers and Sons: Androgynous Relationships in African-West Indian and African-American Novels of Youth.

    ERIC Educational Resources Information Center

    LeSeur, Geta

    1992-01-01

    Four African-American and West Indian novels of childhood illustrate relationships and bonding between mothers and sons: (1) "Go Tell It on the Mountain" (James Baldwin); (2) "Not without Laughter" (Langston Hughes); (3) "Amongst Thistles and Thorns" (Austin Clarke); and (4) "In the Castle of My Skin" (George Lanning). (SLD)

  10. Effects of Parity on Blood Pressure among West African Dogon Women

    PubMed Central

    Taylor, Jacquelyn Y.; Sampson, Deborah A.; Anderson, Cindy M.; Caldwell, Dennis; Taylor, Andre D.

    2012-01-01

    Objective This study examined the effect of parity on blood pressure (BP) readings and BMI among rural West African Dogon women. Design Correlational research design. Setting Sangha, West Africa Participants 133 West African Dogon Women Methods Demographic survey including age, number of children, history of hypertension, and village affiliation. BP readings were taken in accordance with JNC-7 guidelines. BMI was calculated from height and weight. Results Women with BP readings diagnostic of hypertension were typically older (M = 55.72 years) than those who were normotensive (M = 42.40). However, BMI, on average, was within normal range for both groups (22.81 and 22.15, respectively). A statistically significant difference was found between number of children and systolic BP (SBP), P = .015, with those having 5 or more children with higher SBP than those with one to three children. A statistically significant difference, P = .001, was found between hypertension and normotensive diagnostic groups. Conclusions This study shows that increased parity of five or more children may contribute to West African Dogon women’s risk factors for hypertension in terms of increased SBP. Because BMI was within normal range for both groups of women, it was not shown to be an independent risk factor for hypertension in this sample. Further studies, with larger samples followed throughout their childbearing years (before, during, and after each pregnancy), are needed before more definitive conclusions can be made regarding the effects of parity on BMI and BP among rural West African Dogon women. PMID:22870582

  11. Shaping Futures and Feminisms: Qur'anic Schools in West African Francophone Fiction

    ERIC Educational Resources Information Center

    Edwin, Shirin

    2011-01-01

    This article examines the representation of female education in Qur'anic schools in a selection of West African francophone novels. I argue that in being the earliest form of education for most Muslim women and also a neglected topic of scholarly interest, the Qur'anic school shapes their feminisms in more significant ways than has been…

  12. Comparative Analyses of Physics Candidates Scores in West African and National Examinations Councils

    ERIC Educational Resources Information Center

    Utibe, Uduak James; Agah, John Joseph

    2015-01-01

    The study is a comparative analysis of physics candidates' scores in West African and National Examinations Councils. It also investigates influence of gender. Results of 480 candidates were randomly selected form three randomly selected Senior Science Colleges using the WASSCE and NECOSSCE computer printout sent to the schools, transformed using…

  13. Learning Across Disciplines: An Approach to West African Music.

    ERIC Educational Resources Information Center

    Morin, Francine

    2003-01-01

    Describes how to teach about world music, specifically music of West Africa, using an interdisciplinary inquiry approach. Explains that questions are generated and the teacher develops the learning experience. Provides examples at the fourth grade level as well as information on resources and musical examples. (CMK)

  14. West-African trypanosomiasis in a returned traveller from Ghana: an unusual cause of progressive neurological decline.

    PubMed

    Elliott, Ivo; Patel, Trupti; Shah, Jagrit; Venkatesan, Pradhib

    2014-08-14

    West-African trypanosomiasis caused by Trypanosoma brucei gambiense is a rare imported infection presenting with somnolence, lymphadenopathy and wide-ranging neurological symptoms. A 67-year-old Caucasian man presented with a 10-month history of cognitive deterioration, ataxic gait, somnolence and urinary incontinence. His symptoms had progressed more rapidly over the course of a month prior to admission. Serological testing confirmed a diagnosis of West-African trypanosomiasis. The patient was successfully treated with eflornithine and made a good recovery. West-African trypanosomiasis should be considered in the differential diagnosis of unexplained cognitive decline in those with a relevant travel history. If left untreated, the condition is universally fatal.

  15. Exploring HIV knowledge, risk and protective factors among west African forced migrants in New York City.

    PubMed

    Akinsulure-Smith, Adeyinka M

    2014-06-01

    Because of ongoing political and social instability throughout the continent, many Africans have become forced migrants. Unlike immigrants who choose to migrate, forced migrants flee their countries in search of safety and often endure multiple traumatic events during their migration. They are often unprepared for new risks in their adopted country. There is a high incidence of newly-diagnosed HIV cases among West African immigrants in the New York City metropolitan area, but little research to date to understand why this might occur. In order to gain insight, the current pilot study explored HIV knowledge, risk and protective behaviors among 52 West African-born forced migrants in New York City. HIV risk behavior came primarily from unprotected heterosexual activities. While most participants were very knowledgeable about HIV transmission and risk factors, almost half reported that they had not used condoms during sexual activities in the past 6 months. Women were more knowledgeable about HIV transmission, yet reported significantly more STDs than men. Many participants did not know about HIV/AIDS treatments and could not identify HIV/AIDS services and resources within their immigrant communities. Factors influencing HIV risk and protective behaviors among this population are identified and discussed. Suggestions for future research and strategies to reduce risky behaviors while enhancing protective ones among forced West African migrants are highlighted.

  16. Recent climatological trend of the Saharan heat low and its impact on the West African climate

    NASA Astrophysics Data System (ADS)

    Lavaysse, Christophe; Flamant, Cyrille; Evan, Amato; Janicot, Serge; Gaetani, Marco

    2015-10-01

    The Saharan heat low (SHL) plays a pivotal role in the West African monsoon system in spring and summer. The recent trend in SHL activity has been analysed using two sets of numerical weather prediction (NWP) model reanalyses and Atmospheric Models Intercomparison Project simulations from 15 climate models performed in the framework of the 5th Coupled Models Intercomparison Project (CMIP5) exercise. A local increase of temperature in the Sahara during the 90s is found in the two sets of NWP models temperature. This increase is stronger within the SHL region than over the surrounding areas. Using different temporal filters (under 25 days, 25-100 days and above 300 days), we show that this is accompanied by a slight but widespread increase of temperature, and a change in the filtered signal under 25 days during the transition period of the 90s. We also show that SHL pulsations occurring at different time scales impact the West Africa climate on a variety of spatial scales, from the regional scale (for the high band pass) to the synoptic scale (for the low band pass signal). Despite a large variability in the temporal trends for 15 climate models from the CMIP5 project, the warming trend in the 90s is observed in the models ensemble mean. Nevertheless, large discrepancies are found between the NWP models reanalyses and the climate model simulations regarding the spatial and temporal evolutions of the SHL as well as its impact on West African climate at the different time scales. These comparisons also reveal that climate models represent the West African monsoon interactions with SHL pulsations quite differently. We provide recommendations to use some of them depending on the time scales of the processes at play (synoptic, seasonal, interannual) and based on key SHL metrics (location, mean intensity, global trend, interaction with the West African monsoon dynamics).

  17. Viruses other than arenaviruses from West African wild mammals

    PubMed Central

    Kemp, Graham E.

    1975-01-01

    At least thirty-seven different viruses have been isolated from wild mammals in West Africa since 1962. Some of these, including Lassa virus, are already known to cause serious human morbidity and mortality. Crimean haemorrhagic fever-Congo virus, Dugbe virus, Mokola virus, and a smallpox-like agent from a gerbil in Dahomey are briefly discussed. An account of social and ecologic factors affecting man, domestic animals, and their interaction with wild mammals is given. PMID:1085217

  18. The West African Ebola outbreak: finishing the job, preparing for future.

    PubMed

    Parsons, Clare; Naeem Ahmad, Umar

    2015-08-01

    As the West African Ebola Outbreak moves towards the final stages, we must consider the importance of remaining work and take heed of lessons learned in preparation for future outbreaks. Several issues pertinent to preparedness must be considered, including the remaining animal reservoir and potential for sexual transmission. Testing must be accessible and contact tracing robust to trace the last patient. Improved infection control procedures alongside education and training require guaranteed supply chains and ongoing funding. Effort must be sustained to prevent an even greater catastrophe than the one inflicted on West Africa today. PMID:26160255

  19. Evidence of Henipavirus Infection in West African Fruit Bats

    PubMed Central

    Hayman, David T. S.; Suu-Ire, Richard; Breed, Andrew C.; McEachern, Jennifer A.; Wang, Linfa; Wood, James L. N.; Cunningham, Andrew A.

    2008-01-01

    Henipaviruses are emerging RNA viruses of fruit bat origin that can cause fatal encephalitis in man. Ghanaian fruit bats (megachiroptera) were tested for antibodies to henipaviruses. Using a Luminex multiplexed microsphere assay, antibodies were detected in sera of Eidolon helvum to both Nipah (39%, 95% confidence interval: 27–51%) and Hendra (22%, 95% CI: 11–33%) viruses. Virus neutralization tests further confirmed seropositivity for 30% (7/23) of Luminex positive serum samples. Our results indicate that henipavirus is present within West Africa. PMID:18648649

  20. West African Ebola epidemic: lessons and a call to action

    PubMed Central

    Ameme, Donne Kofi

    2015-01-01

    The current Ebola epidemic in West Africa is unprecedented in terms of magnitude and spread. A year after the index case had been identified in a remote village in Guinea, over 17,000 cases and 6,000 deaths were reported in Africa and beyond. Many interventions have been implemented but the outbreak rages on. This paper examines key gaps in the interventions and calls for evidence-based actions to reverse the trend and prevent future epidemics of this proportion. PMID:26740834

  1. The food of Near East, North West and Western African regions.

    PubMed

    Burlingame, Barbara

    2003-01-01

    Among the countries that can be classified as Near East Africa, North West Africa, and Western Africa, there is a great diversity of foods and dietary patterns. Prevalence of undernourishment as defined by FAO using dietary energy supply data, varies dramatically among these countries, with Tunisia in the lowest prevalence category (<2.5%), and Sierra Leone in the highest prevalence category (>35%). Throughout the 1960's, the dietary energy supply of North West African and Western African countries was similar. However, since the 1970s a great and consistent improvement has been seen in North and North West African countries. Both the proportion and number of undernourished in North Africa is now very similar to that of North America. Oil use, energy from fat, and protein from plant versus animal sources account for a large part of the food pattern differences between countries in these regions. Using Tunisia and Sierra Leone as examples again, dietary diversity as measured by the percentage of energy from foods other than starchy staples, is about 50% in the former, while in the latter, it is only 36%. Fatty fruits such as olives, cocoa and palm fruit have a special role in both the diet and the economies of the region. PMID:14505995

  2. The food of Near East, North West and Western African regions.

    PubMed

    Burlingame, Barbara

    2003-01-01

    Among the countries that can be classified as Near East Africa, North West Africa, and Western Africa, there is a great diversity of foods and dietary patterns. Prevalence of undernourishment as defined by FAO using dietary energy supply data, varies dramatically among these countries, with Tunisia in the lowest prevalence category (<2.5%), and Sierra Leone in the highest prevalence category (>35%). Throughout the 1960's, the dietary energy supply of North West African and Western African countries was similar. However, since the 1970s a great and consistent improvement has been seen in North and North West African countries. Both the proportion and number of undernourished in North Africa is now very similar to that of North America. Oil use, energy from fat, and protein from plant versus animal sources account for a large part of the food pattern differences between countries in these regions. Using Tunisia and Sierra Leone as examples again, dietary diversity as measured by the percentage of energy from foods other than starchy staples, is about 50% in the former, while in the latter, it is only 36%. Fatty fruits such as olives, cocoa and palm fruit have a special role in both the diet and the economies of the region.

  3. Understanding the mechanisms behind the West African Monsoon northward extension during Mid-Holocene

    NASA Astrophysics Data System (ADS)

    Gaetani, Marco; Messori, Gabriele; Zhang, Qiong; Flamant, Cyrille; Evan, Amato T.; Pausata, Francesco S. R.

    2016-04-01

    Understanding the West African monsoon (WAM) dynamics in the mid-Holocene (MH) is a crucial issue in climate modelling, because numerical models typically fail to reproduce the extensive precipitation suggested by proxy evidence. This discrepancy is largely due to unrealistic imposed land surface cover and aerosols. Numerical experiments are conducted by imposing a "green Sahara", along with a reduced dust concentration in the atmosphere, coherently with the MH environment in the region, and the atmospheric dynamics response and impact on precipitation are investigated. The response of the WAM system to the imposed conditions shows a dramatic augmentation of the precipitation across West Africa up to the Mediterranean coast. This follows a substantial reorganization of the regional circulation, with some monsoonal circulation features (Saharan heat low, African easterly jet, African easterly waves) weakened in favour of deep convection development over land. The simulated response is dominated by land cover changes, and the reduction in dust concentration further enhances the changes induced by the "green Sahara". The intensity and meridional extent of the WAM is fully consistent with proxy evidence. The results for the MH WAM present important implications for understanding future climate scenarios in the region, in the perspective of projected wetter conditions in West Africa.

  4. Investigating the zoonotic origin of the West African Ebola epidemic.

    PubMed

    Marí Saéz, Almudena; Weiss, Sabrina; Nowak, Kathrin; Lapeyre, Vincent; Zimmermann, Fee; Düx, Ariane; Kühl, Hjalmar S; Kaba, Moussa; Regnaut, Sebastien; Merkel, Kevin; Sachse, Andreas; Thiesen, Ulla; Villányi, Lili; Boesch, Christophe; Dabrowski, Piotr W; Radonić, Aleksandar; Nitsche, Andreas; Leendertz, Siv Aina J; Petterson, Stefan; Becker, Stephan; Krähling, Verena; Couacy-Hymann, Emmanuel; Akoua-Koffi, Chantal; Weber, Natalie; Schaade, Lars; Fahr, Jakob; Borchert, Matthias; Gogarten, Jan F; Calvignac-Spencer, Sébastien; Leendertz, Fabian H

    2014-12-30

    The severe Ebola virus disease epidemic occurring in West Africa stems from a single zoonotic transmission event to a 2-year-old boy in Meliandou, Guinea. We investigated the zoonotic origins of the epidemic using wildlife surveys, interviews, and molecular analyses of bat and environmental samples. We found no evidence for a concurrent outbreak in larger wildlife. Exposure to fruit bats is common in the region, but the index case may have been infected by playing in a hollow tree housing a colony of insectivorous free-tailed bats (Mops condylurus). Bats in this family have previously been discussed as potential sources for Ebola virus outbreaks, and experimental data have shown that this species can survive experimental infection. These analyses expand the range of possible Ebola virus sources to include insectivorous bats and reiterate the importance of broader sampling efforts for understanding Ebola virus ecology.

  5. Investigating the zoonotic origin of the West African Ebola epidemic

    PubMed Central

    Marí Saéz, Almudena; Weiss, Sabrina; Nowak, Kathrin; Lapeyre, Vincent; Zimmermann, Fee; Düx, Ariane; Kühl, Hjalmar S; Kaba, Moussa; Regnaut, Sebastien; Merkel, Kevin; Sachse, Andreas; Thiesen, Ulla; Villányi, Lili; Boesch, Christophe; Dabrowski, Piotr W; Radonić, Aleksandar; Nitsche, Andreas; Leendertz, Siv Aina J; Petterson, Stefan; Becker, Stephan; Krähling, Verena; Couacy-Hymann, Emmanuel; Akoua-Koffi, Chantal; Weber, Natalie; Schaade, Lars; Fahr, Jakob; Borchert, Matthias; Gogarten, Jan F; Calvignac-Spencer, Sébastien; Leendertz, Fabian H

    2015-01-01

    The severe Ebola virus disease epidemic occurring in West Africa stems from a single zoonotic transmission event to a 2-year-old boy in Meliandou, Guinea. We investigated the zoonotic origins of the epidemic using wildlife surveys, interviews, and molecular analyses of bat and environmental samples. We found no evidence for a concurrent outbreak in larger wildlife. Exposure to fruit bats is common in the region, but the index case may have been infected by playing in a hollow tree housing a colony of insectivorous free-tailed bats (Mops condylurus). Bats in this family have previously been discussed as potential sources for Ebola virus outbreaks, and experimental data have shown that this species can survive experimental infection. These analyses expand the range of possible Ebola virus sources to include insectivorous bats and reiterate the importance of broader sampling efforts for understanding Ebola virus ecology. PMID:25550396

  6. Influence of 21st century atmospheric and sea surface temperature forcing on West African climate

    SciTech Connect

    Skinner, Chris B; Ashfaq, Moetasim; Diffenbaugh, Noah

    2011-01-01

    he persistence of extended drought events throughout West Africa during the 20th century has motivated a substantial effort to understand the mechanisms driving African climate variability, as well as the possible response to elevated greenhouse gas (GHG) forcing. We use an ensemble of global climate model experiments to examine the relative roles of future direct atmospheric radiative forcing and SST forcing in shaping potential future changes in boreal summer precipitation over West Africa. We find that projected increases in precipitation throughout the Western Sahel result primarily from direct atmospheric radiative forcing. The changes in atmospheric forcing generate a slight northward displacement and weakening of the African easterly jet (AEJ), a strengthening of westward monsoon flow onto West Africa and an intensification of the tropical easterly jet (TEJ). Alternatively, we find that the projected decreases in precipitation over much of the Guinea Coast region are caused by SST changes that are induced by the atmospheric radiative forcing. The changes in SSTs generate a weakening of the monsoon westerlies and the TEJ, as well as a decrease in low-level convergence and resultant rising air throughout the mid levels of the troposphere. Our experiments suggest a potential shift in the regional moisture balance of West Africa should global radiative forcing continue to increase, highlighting the importance of climate system feedbacks in shaping the response of regional-scale climate to global-scale changes in radiative forcing.

  7. Impact of the Madden Julian Oscillation on the summer West African monsoon in AMIP simulations

    NASA Astrophysics Data System (ADS)

    Niang, Coumba; Mohino, Elsa; Gaye, Amadou T.; Omotosho, J. Bayo

    2016-06-01

    At intraseasonal timescales, convection over West Africa is modulated by the Madden Julian Oscillation (MJO). In this work we investigate the simulation of such relationship by 11 state-of-the-art atmospheric general circulation models runs with prescribed observed sea surface temperatures. In general, the Atmospheric Model Intercomparison Project simulations show good skill in capturing the main characteristics of the summer MJO as well as its influence on convection and rainfall over West Africa. Most models simulate an eastward spatiotemporal propagation of enhanced and suppressed convection similar to the observed MJO, although their signal over West Africa is weaker in some models. In addition, the ensemble average of models' composites gives a better performance in reproducing the main features and timing of the MJO and its impact over West Africa. The influence on rainfall is well captured in both Sahel and Guinea regions thereby adequately producing the transition between positive and negative rainfall anomalies through the different phases as in the observations. Furthermore, the results show that a strong active convection phase is clearly associated with a stronger African Easterly Jet (AEJ) but the weak convective phase is associated with a much weaker AEJ. Our analysis of the equatorial waves suggests that the main impact over West Africa is established by the propagation of low-frequency waves within the MJO and Rossby spectral peaks. Results from the simulations confirm that it may be possible to predict anomalous convection over West Africa with a time lead of 15-20 day.

  8. Milk production of West African Dwarf goats in the Gambia.

    PubMed

    Jaitner, J; Njie, M; Corr, N; Dempfle, L

    2006-04-01

    Goats are important in the low-input systems of West Africa and their main importance lies in their role for income and saving. In addition, it is known that milk offtake for home consumption is also important. In order to obtain information about the real importance of milk offtake, a recording scheme was operated in 27 villages in the Central River Division of The Gambia from July 1998 until January 2000. Detailed information was obtained from about 1500 kiddings. In the recording scheme, any sheep being milked as well as the goats of the International Trypanotolerance Centre nucleus flock were also recorded. In the villages, 36% of all lactations were used for milk offtake, but the fraction milked was lower for the first two lactations. The average length of lactation was 127 days and the average daily milk offtake was 0.18 L. Goats are milked once a day and the residual milk is left for the kids. Milking starts about one week after parturition and stops when the goat becomes pregnant or the kid(s) die or the goat is drying off. The repeatability of the 90-day milk offtake was 0.24 +/- 0.09. Sixty-five percent of goat owner were women and a large fraction of goat owners also owned cattle. Goat milk was used exclusively for home consumption. It is concluded that in breeding and extension work more attention should be given to aspects of milk production.

  9. Outcome of Radioiodine Therapy in a West African Population.

    PubMed

    Onimode, Yetunde A; Ankrah, Alfred; Adedapo, Kayode S

    2016-01-01

    Hyperthyroidism continues to be a pressing public health concern in West Africa. Its prevalence in Africa has been quoted as 1.2%-9.9%, with Graves' disease as its most common cause. Radioiodine-131 (RAI) therapy of hyperthyroidism recently commenced in two government hospitals in Ghana and Nigeria. This is a retrospective analysis of consecutive patients treated with RAI for primary hyperthyroidism at the National Centre for Radiotherapy and Nuclear Medicine (NCRNM) from 2008-2013, and in the University College Hospital (UCH) from 2006-2013. Cure was defined as euthyroidism or hypothyroidism occurring at 6 months post-RAI. Data were analysed using SPSS version 21 and Epi Info version, categorical data were evaluated with the Chi-square test and Fisher's exact test. 94 patients were studied, aged 20-74 years; 78 were females, and 16 were males. 38 were Ghanaian and 56 Nigerian. The presence of thyroid-associated ophthalmopathy (TAO) made cure less likely (χ(2) P = 0.006, odds ratio = 0.118; 95% confidence interval, 0.027-0.518). Other factors assessed proved to be insignificant. Our findings suggest that hyperthyroid patients with TAO will benefit from a higher RAI dose than their counterparts without TAO. PMID:26912975

  10. Leading and Trailing Anvil Clouds of West African Squall Lines

    NASA Technical Reports Server (NTRS)

    Centrone, Jasmine; Houze, Robert A.

    2011-01-01

    The anvil clouds of tropical squall-line systems over West Africa have been examined using cloud radar data and divided into those that appear ahead of the leading convective line and those on the trailing side of the system. The leading anvils are generally higher in altitude than the trailing anvil, likely because the hydrometeors in the leading anvil are directly connected to the convective updraft, while the trailing anvil generally extends out of the lower-topped stratiform precipitation region. When the anvils are subdivided into thick, medium, and thin portions, the thick leading anvil is seen to have systematically higher reflectivity than the thick trailing anvil, suggesting that the leading anvil contains numerous larger ice particles owing to its direct connection to the convective region. As the leading anvil ages and thins, it retains its top. The leading anvil appears to add hydrometeors at the highest altitudes, while the trailing anvil is able to moisten a deep layer of the atmosphere.

  11. Bayesian species delimitation in West African forest geckos (Hemidactylus fasciatus)

    PubMed Central

    Leaché, Adam D.; Fujita, Matthew K.

    2010-01-01

    Genealogical data are an important source of evidence for delimiting species, yet few statistical methods are available for calculating the probabilities associated with different species delimitations. Bayesian species delimitation uses reversible-jump Markov chain Monte Carlo (rjMCMC) in conjunction with a user-specified guide tree to estimate the posterior distribution for species delimitation models containing different numbers of species. We apply Bayesian species delimitation to investigate the speciation history of forest geckos (Hemidactylus fasciatus) from tropical West Africa using five nuclear loci (and mtDNA) for 51 specimens representing 10 populations. We find that species diversity in H. fasciatus is currently underestimated, and describe three new species to reflect the most conservative estimate for the number of species in this complex. We examine the impact of the guide tree, and the prior distributions on ancestral population sizes (θ) and root age (τ0), on the posterior probabilities for species delimitation. Mis-specification of the guide tree or the prior distribution for θ can result in strong support for models containing more species. We describe a new statistic for summarizing the posterior distribution of species delimitation models, called speciation probabilities, which summarize the posterior support for each speciation event on the starting guide tree. PMID:20519219

  12. Regional Climate Modeling of West African Summer Monsoon Climate: Impact of Historical Boundary Forcing

    NASA Astrophysics Data System (ADS)

    Kebe, I.

    2015-12-01

    In this paper, we analyze and intercompare the performance of an ensemble of three Regional Climate Models (RCMs) driven by three set of Global Climate Models (GCMs), in reproducing seasonal mean climatologies with their annual cycle and the key features of West African summer monsoon over 20 years period (1985-2004) during the present day. The results show that errors in lateral boundary conditions from the GCM members, have an unexpected way on the skill of the RCMs in reproducing regional climate features such as the West African Monsoon features and the annual cycle of precipitation and temperature in terms of outperforming the GCM simulation. It also shows the occurrence of the West African Monsoon jump, the intensification and northward shift of the Saharan Heat Low (SHL) as expressed in some RCMs than the GCMs. Most RCMs also capture the mean annual cycle of precipitation and temperature, including, single and double-peaked during the summer months, in terms of events and amplitude. In a series of RCMs and GCMs experiments between the Sahara region and equatorial Africa, the presence of strong positive meridional temperature gradients at the surface and a strong meridional gradients in the potential temperatures near the surface are obvious, indicating the region of strong vertical shear development enough to establish easterly flow such as the African easterly jet. In addition, the isentropic potential vorticity (IPV) gradient decreases northward in the lower troposphere across northern Africa, with the maximum reversal on the 315-K surface. The region with negative IPV gradient favors the potential instability which has been associated with the growth of easterly waves.

  13. The habitat of petroleum in the Brazilian marginal and west African basins: A biological marker investigation

    SciTech Connect

    Mello, M.R.; Soldan, A.L. ); Maxwell, J.R. ); Figueira, J. )

    1990-05-01

    A geochemical and biological marker investigation of a variety of oils from offshore Brazil and west Africa, ranging in age from Lower Cretaceous to Tertiary, has been done, with the following aims: (1) assessing the depositional environment of source rocks, (2) correlating the reservoired oils, (3) comparing the Brazilian oils with their west African counterparts. The approach was based in stable isotope data; bulk, elemental, and hydrous pyrolysis results; and molecular studies involving quantitative geological marker investigations of alkanes using GC-MS and GC-MS-MS. The results reveal similarities between groups of oils from each side of the Atlantic and suggest an origin from source rocks deposited in five types of depositional environment: lacustrine fresh water, lacustrine saline water, marine evaporitic/carbonate, restricted marine anoxic, and marine deltaic. In west Africa, the Upper Cretaceous marine anoxic succession (Cenomanian-Santonian) appears to be a major oil producer, but in Brazil it is generally immature. The Brazilian offshore oils have arisen mainly from the pre-salt sequence, whereas the African oils show a balance between origins from the pre-salt and marine sequences. The integration of the geochemical and geological data indicate that new frontiers of hydrocarbon exploration in the west African basins must consider the Tertiary reservoirs in the offshore area of Niger Delta, the reservoirs of the rift sequences in the shallow-water areas of south Gabon, Congo, and Cuanza basins, and the reservoirs from the drift sequences (post-salt) in the deep-water areas of Gabon, Congo Cabinda, and Cuanza basins.

  14. On the stationarity of Floods in west African rivers

    NASA Astrophysics Data System (ADS)

    NKA, B. N.; Oudin, L.; Karambiri, H.; Ribstein, P.; Paturel, J. E.

    2014-12-01

    West Africa undergoes a big change since the years 1970-1990, characterized by very low precipitation amounts, leading to low stream flows in river basins, except in the Sahelian region where the impact of human activities where pointed out to justify the substantial increase of floods in some catchments. More recently, studies showed an increase in the frequency of intense rainfall events, and according to observations made over the region, increase of flood events is also noticeable during the rainy season. Therefore, the assumption of stationarity on flood events is questionable and the reliability of flood evolution and climatic patterns is justified. In this work, we analyzed the trends of floods events for several catchments in the Sahelian and Sudanian regions of Burkina Faso. We used thirteen tributaries of large river basins (Niger, Nakambe, Mouhoun, Comoé) for which daily rainfall and flow data were collected from national hydrological and meteorological services of the country. We used Mann-Kendall and Pettitt tests to detect trends and break points in the annual time series of 8 rainfall indices and the annual maximum discharge records. We compare the trends of precipitation indices and flood size records to analyze the possible causality link between floods size and rainfall pattern. We also analyze the stationary of the frequency of flood exceeding the ten year return period level. The samples were extracted by a Peak over threshold method and the quantification of change in flood frequency was assessed by using a test developed by Lang M. (1995). The results exhibit two principal behaviors. Generally speaking, no trend is detected on catchments annual maximum discharge, but positive break points are pointed out in a group of three right bank tributaries of the Niger river that are located in the sahelian region between 300mm to 650mm. These same catchments show as well an increase of the yearly number of flood greater than the ten year flood since

  15. Redescription of Heliconema africanum (Linstow, 1899) n. comb. (Nematoda: Physalopteridae), a nematode parasite of freshwater eels (Anguilla spp.) in South Africa.

    PubMed

    Moravec, František; Taraschewski, Horst; Weyl, Olaf L F

    2013-07-01

    The little-known nematode species Heliconema africanum (Linstow, 1899) n. comb. (Physalopteridae) is redescribed based on light and scanning electron microscopical examinations of specimens collected from the stomach of the African longfin eel Anguilla mossambica (Peters) in the Nahoon River, Eastern Cape Province, South Africa. This species, previously misidentified as Heliconema longissimum (Ortlepp, 1922), is a common parasite of eels in South Africa. The systematic status of H. longissimum, a species originally described from unidentified Australian snakes, is unclear and probably several morphologically closely related species have been included under this name.

  16. Redescription of Heliconema africanum (Linstow, 1899) n. comb. (Nematoda: Physalopteridae), a nematode parasite of freshwater eels (Anguilla spp.) in South Africa.

    PubMed

    Moravec, František; Taraschewski, Horst; Weyl, Olaf L F

    2013-07-01

    The little-known nematode species Heliconema africanum (Linstow, 1899) n. comb. (Physalopteridae) is redescribed based on light and scanning electron microscopical examinations of specimens collected from the stomach of the African longfin eel Anguilla mossambica (Peters) in the Nahoon River, Eastern Cape Province, South Africa. This species, previously misidentified as Heliconema longissimum (Ortlepp, 1922), is a common parasite of eels in South Africa. The systematic status of H. longissimum, a species originally described from unidentified Australian snakes, is unclear and probably several morphologically closely related species have been included under this name. PMID:23793500

  17. Dry intrusions in the West African monsoon mid-troposphere during the AMMA experiment

    NASA Astrophysics Data System (ADS)

    Deme, A.; Roca, R.

    2009-04-01

    Mid-troposphere dry air patches (RH < 10%) have been recently detected over the African monsoon region and in particular over Sahel. At 500 hPa, these dry air features are thought to play a complex role onto convection: inhibition isolated convective cells but favouring already organized convection by feeding rear-inflow currents with dry air. The inhibiting action of the dry air onto convection comes from the temperature inversion induced by radiation at the bottom of the dry layer and/or by entrainment of dry air in ascending parcel that decreases its buoyancy. The organizing effect is associated to mesoscale currents within and around long lasting squall lines. This mid-tropospheric dry air has been shown to originate from the mid-latitudes upper level jets, therefore coined extra-tropical dry intrusions.Among all the forcings that control the dynamics of the West African monsoon, the role of a dry mid-troposphere needs to be clarified. The present study is dedicated to this objective and it is focused on extra-tropical dry air intrusions in the West African mid-troposphere during the AMMA campaign. The low level dynamics is documented (African Easterly Jet, African Easterly Wave) thanks to the NCEP operational analysis. It is completed by the radiosondes especially for the temperature and water vapor distribution. Back-trajectory are computed in order to highlight the origin of the tropospheric air mass. Finally Meteosat Second Generation derived water vapor and cloud and rainfall parameters are used to characterize the convective activity and its moist environment. Dry intrusions in the African mid troposphere during the summer 2006 have been shown to be associated with two major modes of occurrences: a 40-50 days mode and a 10-20 days mode. The long mode exhibits negative anomaly of the rainfall and a very large scale structure covering the whole West Africa region when occurring while the short mode is more restricted to the Sahelian longitude. Similarly

  18. Association studies in QTL regions linked to bovine trypanotolerance in a West African crossbred population.

    PubMed

    Dayo, G K; Gautier, M; Berthier, D; Poivey, J P; Sidibe, I; Bengaly, Z; Eggen, A; Boichard, D; Thevenon, S

    2012-04-01

    African animal trypanosomosis is a parasitic blood disease transmitted by tsetse flies and is widespread in sub-Saharan Africa. West African taurine breeds have the ability, known as trypanotolerance, to limit parasitaemia and anaemia and remain productive in enzootic areas. Several quantitative trait loci (QTL) underlying traits related to trypanotolerance have been identified in an experimentally infected F(2) population resulting from a cross between taurine and zebu cattle. Although this information is highly valuable, the QTL remain to be confirmed in populations subjected to natural conditions of infection, and the corresponding regions need to be refined. In our study, 360 West African cattle were phenotyped for the packed cell volume control under natural conditions of infection in south-western Burkina Faso. Phenotypes were assessed by analysing data from previous cattle monitored over 2 years in an area enzootic for trypanosomosis. We further genotyped for 64 microsatellite markers mapping within four previously reported QTL on BTA02, BTA04, BTA07 and BTA13. These data enabled us to estimate the heritability of the phenotype using the kinship matrix between individuals computed from genotyping data. Thus, depending on the estimators considered and the method used, the heritability of anaemia control ranged from 0.09 to 0.22. Finally, an analysis of association identified an allele of the MNB42 marker on BTA04 as being strongly associated with anaemia control, and a candidate gene, INHBA, as being close to that marker. PMID:22404348

  19. The Genetic Contribution of West-African Ancestry to Protection against Central Obesity in African-American Men but Not Women: Results from the ARIC and MESA Studies

    PubMed Central

    Klimentidis, Yann C.; Arora, Amit; Zhou, Jin; Kittles, Rick; Allison, David B.

    2016-01-01

    Over 80% of African-American (AA) women are overweight or obese. A large racial disparity between AA and European-Americans (EA) in obesity rates exists among women, but curiously not among men. Although socio-economic and/or cultural factors may partly account for this race-by-sex interaction, the potential involvement of genetic factors has not yet been investigated. Among 2814 self-identified AA in the Atherosclerosis Risk in Communities study, we estimated each individual's degree of West-African genetic ancestry using 3437 ancestry informative markers. We then tested whether sex modifies the association between West-African genetic ancestry and body mass index (BMI), waist-circumference (WC), and waist-to-hip ratio (WHR), adjusting for income and education levels, and examined associations of ancestry with the phenotypes separately in males and females. We replicated our findings in the Multi-Ethnic Study of Atherosclerosis (n = 1611 AA). In both studies, we find that West-African ancestry is negatively associated with obesity, especially central obesity, among AA men, but not among AA women (pinteraction = 4.14 × 10−5 in pooled analysis of WHR). In conclusion, our results suggest that the combination of male gender and West-African genetic ancestry is associated with protection against central adiposity, and suggest that the large racial disparity that exists among women, but not men, may be at least partly attributed to genetic factors. PMID:27313598

  20. A whole genome Bayesian scan for adaptive genetic divergence in West African cattle

    PubMed Central

    2009-01-01

    Background The recent settlement of cattle in West Africa after several waves of migration from remote centres of domestication has imposed dramatic changes in their environmental conditions, in particular through exposure to new pathogens. West African cattle populations thus represent an appealing model to unravel the genome response to adaptation to tropical conditions. The purpose of this study was to identify footprints of adaptive selection at the whole genome level in a newly collected data set comprising 36,320 SNPs genotyped in 9 West African cattle populations. Results After a detailed analysis of population structure, we performed a scan for SNP differentiation via a previously proposed Bayesian procedure including extensions to improve the detection of loci under selection. Based on these results we identified 53 genomic regions and 42 strong candidate genes. Their physiological functions were mainly related to immune response (MHC region which was found under strong balancing selection, CD79A, CXCR4, DLK1, RFX3, SEMA4A, TICAM1 and TRIM21), nervous system (NEUROD6, OLFM2, MAGI1, SEMA4A and HTR4) and skin and hair properties (EDNRB, TRSP1 and KRTAP8-1). Conclusion The main possible underlying selective pressures may be related to climatic conditions but also to the host response to pathogens such as Trypanosoma(sp). Overall, these results might open the way towards the identification of important variants involved in adaptation to tropical conditions and in particular to resistance to tropical infectious diseases. PMID:19930592

  1. Spatio-temporal evolution of the West African monsoon during the last deglaciation

    NASA Astrophysics Data System (ADS)

    Weldeab, Syee; Frank, Martin; Stichel, Torben; Haley, Brian; Sangen, Mark

    2011-07-01

    On the basis of a multi-proxy data set from the Gulf of Guinea (eastern equatorial Atlantic) we reconstruct the spatio-temporal evolution of the West African monsoon (WAM) and present evidence for a decoupling between latitudinal shifts of the rain belt and WAM intensification. The onset of deglacial monsoon invigoration at ˜16,600 years before present lagged northward migration of a weak rainfall zone by ˜2800 years. Conversely, during the Younger Dryas (YD) time interval, WAM precipitation was severely reduced but we find no evidence for a large-scale retreat of the rainfall front. This observation is not in agreement with the hypothesis of a large-scale shift of the intertropical convergence zone south of the tropical WAM region during the YD. Our results can be better reconciled with the newly emerging concept of a strong influence of Tropical Easterly and African Easterly Jets on modern WAM.

  2. On the mathematical analysis of Ebola hemorrhagic fever: deathly infection disease in West African countries.

    PubMed

    Atangana, Abdon; Goufo, Emile Franc Doungmo

    2014-01-01

    For a given West African country, we constructed a model describing the spread of the deathly disease called Ebola hemorrhagic fever. The model was first constructed using the classical derivative and then converted to the generalized version using the beta-derivative. We studied in detail the endemic equilibrium points and provided the Eigen values associated using the Jacobian method. We furthered our investigation by solving the model numerically using an iteration method. The simulations were done in terms of time and beta. The study showed that, for small portion of infected individuals, the whole country could die out in a very short period of time in case there is not good prevention.

  3. Instrumental evidence of an unusually strong West African Monsoon in the 19th century

    NASA Astrophysics Data System (ADS)

    Gallego, David; Ordoñez, Paulina; Ribera, Pedro; Peña-Ortiz, Cristina; Garcia-Herrera, Ricardo; Vega, Inmaculada; Gomez, Francisco de Paula

    2016-04-01

    The precipitation in the Sahel -which is mainly controlled by the dynamics of the West African Monsoon-, has been in the spot of the climate community for the last three decades due to the persistence of the drought period that started in the 1970s. Unfortunately, reliable meteorological series in this area are only available since the beginning of the 20th Century, thus limiting our understanding of the significance of this period from a long term perspective. Currently, our knowledge of what happened in times previous to the 20th Century essentially relies in documentary or proxy sources. In this work, we present the first instrumental evidence of a 50 year-long period characterised by an unusually strong West African monsoon in the19th Century. Following the recent advances in the generation of climatic indices based on data from ship's logbooks, we used historical wind observations to compute a new index (the so-called ASWI) for characterising the strength of the West African Monsoon. The ASWI is based in the persistence of the southwesterly winds in the [29°W-17°W;7°N-13°N] area and it has been possible to compute it since 1790 for July and since 1839 for August and September. We show that the ASWI is a reliable measure of the monsoon's strength and the Sahelian rainfall. Our new series clearly shows the well-known drought period starting in the 1970s. During this dry period, the West African Monsoon was particularly weak and interestingly, we found that since then, the correlations with different climatic patterns such as the Pacific and Atlantic "El Niño" changed significantly in relation to those of the previous century. Remarkably, our results also show that the period 1839-1890 was characterised by an unusually strong and persistent monsoon. Notwithstanding, two of the few dry years within this period were concurrent with large volcanic eruptions in the Northern Hemisphere. This latter result supports the recently suggested relationship between major

  4. Seasonal Evolution and Variability Associated with the West African Monsoon System

    NASA Technical Reports Server (NTRS)

    Gu, Guojun; Adler, Robert F.

    2003-01-01

    In this study, we investigate the seasonal variations in surface rainfall and associated large-scale processes in the tropical eastern Atlantic and West African region. The 5-yr (1998-2002) high-quality TRMM rainfall, sea surface temperature (SST), water vapor and cloud liquid water observations are applied along with the NCEP/NCAR reanalysis wind components and a 3-yr (2000-2002) Quickscat satellite-observed surface wind product. Major mean rainfall over West Africa tends to be concentrated in two regions and is observed in two different seasons, manifesting an abrupt shift of the mean rainfall zone during June-July. (i) Near the Gulf of Guinea (about 5 degN), intense convection and rainfall are seen during April-June and roughly follow the seasonality of SST in the tropical eastern Atlantic. (ii) Along the latitudes of about 10 deg. N over the interior West African continent, a second intense rain belt begins to develop from July and remains there during the later summer season. This belt co-exists with a northwardmoved African Easterly Jet (AEJ) and its accompanying horizonal and vertical shear zones, the appearance and intensification of an upper tropospheric Tropical Easterly Jet (TEJ), and a strong low-level westerly flow. Westward-propagating wave signals [ i e . , African easterly waves (AEWs)] dominate the synoptic-scale variability during July-September, in contrast to the evident eastward-propagating wave signals during May- June. The abrupt shift of mean rainfall zone thus turns out to be a combination of two different physical processes: (i) Evident seasonal cycles in the tropical eastern Atlantic ocean which modulate convection and rainfall in the Gulf of Guinea by means of SST thermal forcing and SST-related meridional gradient; (ii) The interaction among the AEJ, TEJ, low-level westerly flow, moist convection and AEWs during July-September which modulates rainfall variability in the interior West Africa, primarily within the ITCZ rain band. Evident

  5. An assessment of West African seahorses in fisheries catch and trade.

    PubMed

    Cisneros-Montemayor, A M; West, K; Boiro, I S; Vincent, A C J

    2016-02-01

    This study provides the first assessment of a heavily traded West African seahorse species, Hippocampus algiricus, and the first information on short-snouted seahorse Hippocampus hippocampus biology in Africa. A total of 219 seahorses were sampled from fisher catch in Senegal and The Gambia, with estimated height at reproductive activity for H. algiricus (161 mm) larger than mean ± S.D. catch height (150 ± 31 mm). Catch composition, height at reproductive activity and potential biases in fishery retention are discussed with regard to the current Convention on International Trade of Endangered Species (CITES) guidelines.

  6. Strong association between west african rainfall and u.s. Landfall of intense hurricanes.

    PubMed

    Gray, W M

    1990-09-14

    Intense hurricanes occurred much more frequently during the period spanning the late 1940s through the late 1960s than during the 1970s and 1980s, except for 1988 and 1989. Seasonal and multidecadal variations of intense hurricane activity are closely linked to seasonal and multidecadal variations of summer rainfall amounts in the Western Sahel region of West Africa. The multidecadal nature of West African precipitation variations and their association with variations of intense Atlantic hurricane activity can be observed in data going back nearly a century. The apparent recent breaking of the 18-year Sahel drought during 1988 and 1989 suggests that the incidence of intense hurricanes making landfall on the U.S. coast and in the Caribbean basin will likely increase during the 1990s and early years of the 21st century to levels of activity notably greater than were observed during the 1970s and 1980s.

  7. The unique resistance and resilience of the Nigerian West African Dwarf goat to gastrointestinal nematode infections

    PubMed Central

    2011-01-01

    Background West African Dwarf (WAD) goats serve an important role in the rural village economy of West Africa, especially among small-holder livestock owners. They have been shown to be trypanotolerant and to resist infections with Haemonchus contortus more effectively than any other known breed of goat. Methods In this paper we review what is known about the origins of this goat breed, explain its economic importance in rural West Africa and review the current status of our knowledge about its ability to resist parasitic infections. Conclusions We suggest that its unique capacity to show both trypanotolerance and resistance to gastrointestinal (GI) nematode infections is immunologically based and genetically endowed, and that knowledge of the underlying genes could be exploited to improve the capacity of more productive wool and milk producing, but GI nematode susceptible, breeds of goats to resist infection, without recourse to anthelmintics. Either conventional breeding allowing introgression of resistance alleles into susceptible breeds, or transgenesis could be exploited for this purpose. Appropriate legal protection of the resistance alleles of WAD goats might provide a much needed source of revenue for the countries in West Africa where the WAD goats exist and where currently living standards among rural populations are among the lowest in the world. PMID:21291550

  8. Daily characteristics of West African summer monsoon precipitation in CORDEX simulations

    NASA Astrophysics Data System (ADS)

    Klutse, Nana Ama Browne; Sylla, Mouhamadou Bamba; Diallo, Ismaila; Sarr, Abdoulaye; Dosio, Alessandro; Diedhiou, Arona; Kamga, Andre; Lamptey, Benjamin; Ali, Abdou; Gbobaniyi, Emiola O.; Owusu, Kwadwo; Lennard, Christopher; Hewitson, Bruce; Nikulin, Grigory; Panitz, Hans-Jürgen; Büchner, Matthias

    2016-01-01

    We analyze and intercompare the performance of a set of ten regional climate models (RCMs) along with the ensemble mean of their statistics in simulating daily precipitation characteristics during the West African monsoon (WAM) period (June-July-August-September). The experiments are conducted within the framework of the COordinated Regional Downscaling Experiments for the African domain. We find that the RCMs exhibit substantial differences that are associated with a wide range of estimates of higher-order statistics, such as intensity, frequency, and daily extremes mostly driven by the convective scheme employed. For instance, a number of the RCMs simulate a similar number of wet days compared to observations but greater rainfall intensity, especially in oceanic regions adjacent to the Guinea Highlands because of a larger number of heavy precipitation events. Other models exhibit a higher wet-day frequency but much lower rainfall intensity over West Africa due to the occurrence of less frequent heavy rainfall events. This indicates the existence of large uncertainties related to the simulation of daily rainfall characteristics by the RCMs. The ensemble mean of the indices substantially improves the RCMs' simulated frequency and intensity of precipitation events, moderately outperforms that of the 95th percentile, and provides mixed benefits for the dry and wet spells. Although the ensemble mean improved results cannot be generalized, such an approach produces encouraging results and can help, to some extent, to improve the robustness of the response of the WAM daily precipitation to the anthropogenic greenhouse gas warming.

  9. Evaluation of Dynamics of the West African Monsoon Jump Simulated by the MIT Regional Climate Model

    NASA Astrophysics Data System (ADS)

    Eltahir, Elfatih A. B.; Im, Eun-Soon

    2015-04-01

    The seasonal advance and retreat of the West African monsoon behaves abrupt northward jump of maximum rainfall from the Guinean coast to the Sahel region. Both global and regional climate models have difficulties in accurately reproducing such a behavior due to its complexity combined the dynamical and physical processes. In this study, we evaluate the performance of the MIT Regional Climate Model (MRCM) in simulating the West African monsoon. For this, 20-year long-term simulation (1989-2008) is performed using the ERAInterim reanalysis as the initial and boundary condition, and the analysis primarily focuses on the dynamics associated with abrupt phase transitions of the monsoon rainfall. We first examine detailed characteristics in terms of the onset, maximum, and retreat of the monsoon rainfall using daily precipitation. We then present the dynamical explanation behind rainfall variability from the analysis of the absolute vorticity near the tropopause and the meridional gradient of boundary-layer entropy within the dynamical theory proposed by Eltahir and Gong (1996). Acknowledgements : This research was supported by the National Research Foundation Singapore through the Singapore MIT Alliance for Research and Technology's Center for Environmental Sensing and Modeling interdisciplinary research program.

  10. Geographical assessment of body measurements and qualitative traits in West African cattle.

    PubMed

    Traoré, Amadou; Koudandé, Delphin Oloronto; Fernández, Iván; Soudré, Albert; Granda, Víctor; Álvarez, Isabel; Diarra, Siaka; Diarra, Fousseyni; Kaboré, Adama; Sanou, Moumouni; Tamboura, Hamidou Hamadou; Goyache, Félix

    2015-12-01

    A total of 1015 adult cows belonging to nine West African cattle breeds were assessed for 16 body measurements and 18 qualitative traits to ascertain the existence of geographical patterns of variation. Sampling was carried out in 29 different provinces of Mali, Burkina Faso and Benin. For body measurements, taurine breeds took lower average values than the zebu breeds. Sanga cattle took intermediate values. Qualitative traits did not allow to differentiate among cattle groups (taurine, zebu or sanga) or breeds. Principal component analysis identified two factors explaining 56.4 and 9.2 % of the variance for body measurements, respectively. Two correspondence analysis dimensions computed on qualitative traits explained a small proportion of the variability (20.8 and 13.5 %, respectively). Contour plots were constructed using the eigenvalues computed for each individual and either factor or dimension identified; confidence regions calculated confirmed that body measurements clearly differentiated zebu and taurine cattle breeds while qualitative traits did not. Factor 1 was projected on a geographical map, using provinces as nodes, to assess breed-free variation for body measurements. A pattern of continuous variation from the Sahel area southwards was identified. Probably, breeding decisions promoting the crosses between zebu-like and taurine cattle are underlying this geographical pattern of variation. The implementation of selection strategies aiming at the increase of the productivity of native West African taurine cattle breeds while avoiding looses in trypanotolerant ability would be highly advisable.

  11. 155,000 years of West African monsoon and ocean thermal evolution.

    PubMed

    Weldeab, Syee; Lea, David W; Schneider, Ralph R; Andersen, Nils

    2007-06-01

    A detailed reconstruction of West African monsoon hydrology over the past 155,000 years suggests a close linkage to northern high-latitude climate oscillations. Ba/Ca ratio and oxygen isotope composition of planktonic foraminifera in a marine sediment core from the Gulf of Guinea, in the eastern equatorial Atlantic (EEA), reveal centennial-scale variations of riverine freshwater input that are synchronous with northern high-latitude stadials and interstadials of the penultimate interglacial and the last deglaciation. EEA Mg/Ca-based sea surface temperatures (SSTs) were decoupled from northern high-latitude millennial-scale fluctuation and primarily responded to changes in atmospheric greenhouse gases and low-latitude solar insolation. The onset of enhanced monsoon precipitation lags behind the changes in EEA SSTs by up to 7000 years during glacial-interglacial transitions. This study demonstrates that the stadial-interstadial and deglacial climate instability of the northern high latitudes exerts dominant control on the West African monsoon dynamics through an atmospheric linkage. PMID:17540896

  12. Dyslipidaemia related to insulin resistance and cardiovascular disease in South Asian and West African populations.

    PubMed

    Ewang-Emukowhate, Mfon; Perera, Dilinika; Wierzbicki, Anthony S D M

    2014-01-01

    The global burden of diabetes and cardiovascular disease (CVD) is increasing. Obesity is rapidly increasing worldwide and is associated with dyslipidaemia, metabolic syndrome (MetS) and type 2 diabetes (T2DM). Excess risks of T2DM and CVD are found in migrant Indian Asian and West African populations but with increasing urbanization similar changes are occurring in the original populations and are likely to predispose to a large increase in worldwide burden of CVD. Genetic and environmental factors interacting together play a role in the lipid patterns observed. Dyslipidaemia in the MetS associated with insulin resistance is characterised by an atherogenic lipid profile comprising elevated triglycerides, low high density lipoprotein cholesterol (HDL-C) and increased numbers of small dense low density lipoprotein particles. The pattern of dyslipidaemia varies across different ethnic groups with increases in triglycerides and a reduction in HDL-C being the commonest pattern in non-Caucasians. This review surveys the literature on dyslipidaemia in Indian Asian and West African populations and how it relates to CVD risk in those populations. It is important that dyslipidaemia and other conventional risk factors for CVD are adequately addressed and managed especially in high-risk populations. PMID:24953401

  13. Influence of Arctic sea-ice and greenhouse gas concentration change on the West African Monsoon.

    NASA Astrophysics Data System (ADS)

    Monerie, Paul-Arthur; Oudar, Thomas; Sanchez-Gomez, Emilia; Terray, Laurent

    2016-04-01

    The Sahelian precipitation are projected to increase in the CNRM-CM5 coupled climate model due to a strengthening of the land-Sea temperature gradient, the increase in the North Atlantic temperature and the deepening of the Heat Low. Arctic Sea-Ice loss impacts the low-level atmospheric circulation through a decrease in the northward heat transport. Some authors have linked the sea-ice loss to a poleward shift of the InterTropical Convergence Zone. Within the CMIP5 models the effect of these mechanisms are not distinguishable and it is difficult to understand the effect of the Arctic sea-ice loss on the West African Monsoon so far. We performed several sensitivity experiments with the CNRM-CM5 coupled climate models by modifying the arctic sea-ice extent and/or the greenhouse gas concentration. We then investigated separately the impact of Arctic sea-ice loss and greenhouse gas concentration increases on the West African Monsoon. The increase in greenhouse gas explains the northward shift and the strengthening of the monsoon. Its effect is stronger with a sea-ice free Arctic that leads to an increase in North Atlantic temperature and in Sahelian precipitation at the end of the rainy season (September-October). We argue that the decrease in sea-ice extent, in the context of the global warming, may moistens the Sahel during the rainy season by changing the pressure, winds and moisture fluxes at low-level.

  14. A new perspective on West African hydroclimate during the last deglaciation

    NASA Astrophysics Data System (ADS)

    Parker, Andrew O.; Schmidt, Matthew W.; Jobe, Zane R.; Slowey, Niall C.

    2016-09-01

    Widespread drought characterized the Heinrich 1 and Younger Dryas cold periods of the last deglaciation throughout much of Africa, causing large increases in dust emissions from the Sahara and Sahel. At the same time, increases in wind strength may have also contributed to dust flux, making it difficult to interpret dust records alone as reflecting changes in rainfall over the region. The Niger River has the third largest drainage basin in Africa and drains most of the Sahara and Sahel and thus preserves and propagates climatic signals. Here, we present new reconstructions of Niger Delta sea surface salinity and Niger River discharge for the last 20,000 years in order to more accurately reconstruct the onset of the Western African Monsoon system. Based on calculated δ18OSEAWATER (δ18OSW) and measured Ba/Ca ratios in planktonic foraminifera, these new records reflect changes in sub-Saharan precipitation across the Niger River Basin in West Africa and reveal that the West African Monsoon system began to intensify several thousand years after the equatorial Monsoon system in Central Africa. We also present new records of primary productivity in the Niger Delta that are related to wind-driven upwelling and show that productivity is decoupled from changes in Niger River discharge. Our results suggest that wind strength, rather than changes in monsoon moisture, was the primary driver of dust emissions from the Sahara and Sahel across the last deglaciation.

  15. Bias reduction in decadal predictions of West African monsoon rainfall using regional climate models

    NASA Astrophysics Data System (ADS)

    Paxian, A.; Sein, D.; Panitz, H.-J.; Warscher, M.; Breil, M.; Engel, T.; Tödter, J.; Krause, A.; Cabos Narvaez, W. D.; Fink, A. H.; Ahrens, B.; Kunstmann, H.; Jacob, D.; Paeth, H.

    2016-02-01

    The West African monsoon rainfall is essential for regional food production, and decadal predictions are necessary for policy makers and farmers. However, predictions with global climate models reveal precipitation biases. This study addresses the hypotheses that global prediction biases can be reduced by dynamical downscaling with a multimodel ensemble of three regional climate models (RCMs), a RCM coupled to a global ocean model and a RCM applying more realistic soil initialization and boundary conditions, i.e., aerosols, sea surface temperatures (SSTs), vegetation, and land cover. Numerous RCM predictions have been performed with REMO, COSMO-CLM (CCLM), and Weather Research and Forecasting (WRF) in various versions and for different decades. Global predictions reveal typical positive and negative biases over the Guinea Coast and the Sahel, respectively, related to a southward shifted Intertropical Convergence Zone (ITCZ) and a positive tropical Atlantic SST bias. These rainfall biases are reduced by some regional predictions in the Sahel but aggravated by all RCMs over the Guinea Coast, resulting from the inherited SST bias, increased westerlies and evaporation over the tropical Atlantic and shifted African easterly waves. The coupled regional predictions simulate high-resolution atmosphere-ocean interactions strongly improving the SST bias, the ITCZ shift and the Guinea Coast and Central Sahel precipitation biases. Some added values in rainfall bias are found for more realistic SST and land cover boundary conditions over the Guinea Coast and improved vegetation in the Central Sahel. Thus, the ability of RCMs and improved boundary conditions to reduce rainfall biases for climate impact research depends on the considered West African region.

  16. Comparative Response of the West African Dwarf Goats to Experimental Infections with Red Sokoto and West African Dwarf Goat Isolates of Haemonchus contortus.

    PubMed

    Ngongeh, Lucas Atehmengo; Onyeabor, Amaechi

    2015-01-01

    Response of the West African Dwarf (WAD) goats to two different isolates of Haemonchus contortus, the Red Sokoto (RS) goat isolate (RSHc) and the WAD goat isolate (WADHc) (isolated from WAD goats), was studied by experimental infections of 4-6-month-old male WAD goat kids. Group 1 and Group 2 goats were each infected with 4500 infective larvae (L3) of RSHc and WADHc, respectively. Group 3 animals served as uninfected control. Prepatent period (PPP), faecal egg counts (FEC), worm burden (WB), body weight (BW), packed cell volume (PCV), and body condition score (BCS) were determined. WAD goats infected with RSHc isolate and the ones infected with WADHc isolate had mean PPP of 19.63 ± 0.26 and 19.50 ± 0.19, respectively. Goats infected with WADHc isolate had significantly higher FEC (P = 0.004) and WB (P = 0.001). BW were significantly higher (P = 0.004) both in the controls and in Group 2 goats infected with WADHc isolate than in Group 1 goats infected with the RSHc isolate. BCS of animals in both infected groups dropped significantly (P = 0.001). There was a significant drop in PCV (P = 0.004) of both infected groups in comparison. Both isolates of H. contortus were pathogenic to the host. PMID:26697224

  17. Comparative Response of the West African Dwarf Goats to Experimental Infections with Red Sokoto and West African Dwarf Goat Isolates of Haemonchus contortus.

    PubMed

    Ngongeh, Lucas Atehmengo; Onyeabor, Amaechi

    2015-01-01

    Response of the West African Dwarf (WAD) goats to two different isolates of Haemonchus contortus, the Red Sokoto (RS) goat isolate (RSHc) and the WAD goat isolate (WADHc) (isolated from WAD goats), was studied by experimental infections of 4-6-month-old male WAD goat kids. Group 1 and Group 2 goats were each infected with 4500 infective larvae (L3) of RSHc and WADHc, respectively. Group 3 animals served as uninfected control. Prepatent period (PPP), faecal egg counts (FEC), worm burden (WB), body weight (BW), packed cell volume (PCV), and body condition score (BCS) were determined. WAD goats infected with RSHc isolate and the ones infected with WADHc isolate had mean PPP of 19.63 ± 0.26 and 19.50 ± 0.19, respectively. Goats infected with WADHc isolate had significantly higher FEC (P = 0.004) and WB (P = 0.001). BW were significantly higher (P = 0.004) both in the controls and in Group 2 goats infected with WADHc isolate than in Group 1 goats infected with the RSHc isolate. BCS of animals in both infected groups dropped significantly (P = 0.001). There was a significant drop in PCV (P = 0.004) of both infected groups in comparison. Both isolates of H. contortus were pathogenic to the host.

  18. Comparative Response of the West African Dwarf Goats to Experimental Infections with Red Sokoto and West African Dwarf Goat Isolates of Haemonchus contortus

    PubMed Central

    Ngongeh, Lucas Atehmengo; Onyeabor, Amaechi

    2015-01-01

    Response of the West African Dwarf (WAD) goats to two different isolates of Haemonchus contortus, the Red Sokoto (RS) goat isolate (RSHc) and the WAD goat isolate (WADHc) (isolated from WAD goats), was studied by experimental infections of 4–6-month-old male WAD goat kids. Group 1 and Group 2 goats were each infected with 4500 infective larvae (L3) of RSHc and WADHc, respectively. Group 3 animals served as uninfected control. Prepatent period (PPP), faecal egg counts (FEC), worm burden (WB), body weight (BW), packed cell volume (PCV), and body condition score (BCS) were determined. WAD goats infected with RSHc isolate and the ones infected with WADHc isolate had mean PPP of 19.63 ± 0.26 and 19.50 ± 0.19, respectively. Goats infected with WADHc isolate had significantly higher FEC (P = 0.004) and WB (P = 0.001). BW were significantly higher (P = 0.004) both in the controls and in Group 2 goats infected with WADHc isolate than in Group 1 goats infected with the RSHc isolate. BCS of animals in both infected groups dropped significantly (P = 0.001). There was a significant drop in PCV (P = 0.004) of both infected groups in comparison. Both isolates of H. contortus were pathogenic to the host. PMID:26697224

  19. Sst and Ghg Impacts On The West African Monsoon Climate: A Superensemble Approach

    NASA Astrophysics Data System (ADS)

    Paeth, H.; Hense, A.

    West African rainfall has been subject to large interdecadal variations during the 20th century. The most prominent feature is a negative trend in annual precipitation after 1960, causing severe drought in the Sahel region and the southern part of West Africa, with some recoverage in recent years. We examine and quantify the influence of ob- served SST changes on low-frequency variability over the subcontinent and compare it with the additional impact of increasing GHG concentrations, as revealed by a su- perensemble of SST-driven experiments. SST is largely responsible for decadal and longer-term variability over the southern part of West Africa, accounting for almost 80 % of monsoonal rainfall variance. The additional impact of the enhanced green- house effect is weak but statistically significant by the year 1980, obviously associ- ated with a positive trend in annual precipitation. This positive trend is also found in GHG-induced coupled climate model projection into the future. The CO2 signal is again weak but statistically significant and consistent with different climate models, as revealed by a superensemble of coupled experiments.

  20. Seasonal evolution of the West African heat low: a climatological perspective

    NASA Astrophysics Data System (ADS)

    Lavaysse, C.; Flamant, C.; Janicot, S.; Parker, D. J.; Lafore, J.-P.; Sultan, B.; Pelon, J.

    2009-08-01

    The West African heat low (WAHL), a region of high surface temperatures and low surface pressures, is a key element of the West African monsoon system. In this study, we propose a method to detect the WAHL in order to monitor its climatological seasonal displacement over West Africa during the period 1979-2001, using the European Centre for Medium-range Weather Forecast (ECMWF) ERA-40 reanalyses. The low-level atmospheric thickness (LLAT), a variable defined as the difference of geopotential heights at 700 and 925 hPa, is used to detect the dilatation of these levels generated by an increase of the temperature. We define grid points with 10% highest values of the LLAT as the WAHL. We show that our method reliably positions the WAHL over areas of high surface temperatures and low surface pressures, and that it is effective at detecting heat lows. In the course of the year, the climatological WAHL is shown to migrate north-westward from a position south of the Darfur mountains in the winter (November-March) to a location over the Sahara, between the Hoggar and the Atlas mountains, during the summer (June-September). The temperature tendency equation is used to investigate the processes controlling the displacement of the WAHL, and more particularly the heating at low levels. The specific period of the onset of the WAHL in its summer location over the Sahara (referred to as the Saharan heat low -SHL- onset) is also analysed during the 1984-2001 period, using complementary brightness temperature data from the European Union-funded Cloud Archive User Service (CLAUS). The climatological onset of the SHL occurs around 20 June, i.e. just before the climatological monsoon onset date. The present study suggests that the onset of the WAHL occurs approximately 5 days before the monsoon onset for the 1984-2001 period. This is confirmed independently by comparing the SHL onset date and the monsoon onset date for the 1984-2001 period. The seasonal evolution of the WAHL for the

  1. Higher Education as an Emerging Strategy for Actualising the Vision 2020 of the Economic Community of West African States (ECOWAS)

    ERIC Educational Resources Information Center

    Biao, Idowu

    2009-01-01

    The Economic Community of West African States (ECOWAS) has just rolled out a document spelling out five major social, economic and environmental goals it wishes to achieve by 2020. These goals are lofty indeed but they can be achieved only with reliance on not only an enlightened citizenry but on 40% of the population that should have received…

  2. Higher Education as an Emerging Strategy for Actualising the Vision 2020 of the Economic Community of West African States (ECOWAS)

    ERIC Educational Resources Information Center

    Biao, Idowu

    2011-01-01

    The Economic Community of West African States (ECOWAS) has just rolled out a document spelling out five major social, economic and environmental goals it wishes to achieve by 2020. These goals are lofty indeed but they can be achieved only with reliance on not only an enlightened citizenry but on 40% of the population that should have received…

  3. Evidence of common signatures of selection in the genomes of West African cattle and the Yoruba human population

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In 1954, Allison found that the sickle-cell anemia mutation in the beta hemoglobin gene was highly prevalent in West African people because it is protective against malaria, so carriers would thrive and leave offspring in spite of the genetic disease. This is one of the earliest evidences of an envi...

  4. The Impact of Desert Dust Aerosol Radiative Forcing on Global and West African Precipitation

    NASA Astrophysics Data System (ADS)

    Jordan, A.; Zaitchik, B. F.; Gnanadesikan, A.; Dezfuli, A. K.

    2015-12-01

    Desert dust aerosols exert a radiative forcing on the atmosphere, influencing atmospheric temperature structure and modifying radiative fluxes at the top of the atmosphere (TOA) and surface. As dust aerosols perturb radiative fluxes, the atmosphere responds by altering both energy and moisture dynamics, with potentially significant impacts on regional and global precipitation. Global Climate Model (GCM) experiments designed to characterize these processes have yielded a wide range of results, owing to both the complex nature of the system and diverse differences across models. Most model results show a general decrease in global precipitation, but regional results vary. Here, we compare simulations from GFDL's CM2Mc GCM with multiple other model experiments from the literature in order to investigate mechanisms of radiative impact and reasons for GCM differences on a global and regional scale. We focus on West Africa, a region of high interannual rainfall variability that is a source of dust and that neighbors major Sahara Desert dust sources. As such, changes in West African climate due to radiative forcing of desert dust aerosol have serious implications for desertification feedbacks. Our CM2Mc results show net cooling of the planet at TOA and surface, net warming of the atmosphere, and significant increases in precipitation over West Africa during the summer rainy season. These results differ from some previous GCM studies, prompting comparative analysis of desert dust parameters across models. This presentation will offer quantitative analysis of differences in dust aerosol parameters, aerosol optical properties, and overall particle burden across GCMs, and will characterize the contribution of model differences to the uncertainty of forcing and climate response affecting West Africa.

  5. Comparative self-concept variances of school children in two English-speaking West African nations.

    PubMed

    Alawiye, O; Alawiye, C Z; Thomas, J I

    1990-03-01

    This study examined the self-concepts of elementary school children in Grades 2, 4, 6, and 8, from two West African nations, Ghana and Gambia. Measures of self-concept in the areas of physical maturity, peer relations, academic success, and school adaptiveness were obtained from 195 Ghanaian and 156 Gambian students. The mean scores of the students were subjected to a series of three-way analyses of variance (ANOVAs). The independent variables were sex, grade level, and nationality. The overall analyses revealed grade level as the most potent variable in the self-concept development of both groups, whereas the sex variable indicated interaction with grade level only in Gambian children. The self-esteem of the children in both nations in the areas of physical maturity, peer relations, and academic success was relatively high and stable. Self-concept developmental patterns showed differences across grade levels in the four self-concept areas being tested.

  6. On the Mathematical Analysis of Ebola Hemorrhagic Fever: Deathly Infection Disease in West African Countries

    PubMed Central

    Atangana, Abdon; Goufo, Emile Franc Doungmo

    2014-01-01

    For a given West African country, we constructed a model describing the spread of the deathly disease called Ebola hemorrhagic fever. The model was first constructed using the classical derivative and then converted to the generalized version using the beta-derivative. We studied in detail the endemic equilibrium points and provided the Eigen values associated using the Jacobian method. We furthered our investigation by solving the model numerically using an iteration method. The simulations were done in terms of time and beta. The study showed that, for small portion of infected individuals, the whole country could die out in a very short period of time in case there is not good prevention. PMID:25688348

  7. Studies on the intestinal parasites in African patients in Owamboland, South West Africa.

    PubMed

    Kyrönseppä, H J; Goldsmid, J M

    1978-01-01

    The paper gives the results of a survey of intestinal parasites among 501 in-patients drawn from four mission hospitals in Owambo and Kavango in northern South West Africa. Most of the patients (90%) were examined twice by the formol-ether concentration method, while the remaining 10% had one stool specimen examined. 10 species of helminths and 3 species of potentially-pathogenic protozoa were recorded--Necator americanus, Strongyloides stercoralis, Strongyloides fuelleborni, Hymenolepis nana, Taenia saginata, Trichuris trichura, Enterobius vermicularis, Fasciola gigantica, Schistosoma mansoni and S. haematobium, and Entamoeba histolytica, Giardia lamblia and Balantidium coli. The loads of Necator americanus were recorded in a few cases. The results are compared with those of some other Central and Southern African countries. 96 blood smears were examined for filaria and 46 patients were tested for bilharzia using the bilharzial skin test. Both groups gave only negative results. PMID:635971

  8. Desertification and a shift of forest species in the West African Sahel

    USGS Publications Warehouse

    Gonzalez, P.

    2001-01-01

    Original field data show that forest species richness and tree density in the West African Sahel declined in the last half of the 20th century. Average forest species richness of areas of 4 km2 in Northwest Senegal fell from 64 ?? 2 species ca 1945 to 43 ?? 2 species in 1993, a decrease significant at p < 0.001. Densities of trees of height ???3 m declined from 10 ?? 0.3 trees ha-1 in 1954 to 7.8 ?? 0.3 trees ha-1 in 1989, also significant at p < 0.001. Standing wood biomass fell 2.1 t ha-1 in the period 1956-1993, releasing CO2 at a rate of 60 kgC person-1 yr-1. These changes have shifted vegetation zones toward areas of higher rainfall at an average rate of 500 to 600 m yr-1. Arid Sahel species have expanded in the north, tracking a concomitant retraction of mesic Sudan and Guinean species to the south. Multivariate analyses identify latitude and longitude, proxies for rainfall and temperature, as the most significant factors explaining tree and shrub distribution. The changes also decreased human carrying capacity to below actual population densities. The rural population of 45 people km-2 exceeded the 1993 carrying capacity, for firewood from shrubs, of 13 people km-2 (range 1 to 21 people km-2). As an adaptation strategy, ecological and socioeconomic factors favor the natural regeneration of local species over the massive plantation of exotic species. Natural regeneration is a traditional practice in which farmers select small field trees that they wish to raise to maturity, protect them, and prune them to promote rapid growth of the apical meristem. The results of this research provide evidence for desertification in the West African Sahel. These documented impacts of desertification foreshadow possible future effects of climate change.

  9. KZai 02 pollen record, an insight into West African monsoon fluctuations during the Last Climatic Cycle

    NASA Astrophysics Data System (ADS)

    Dalibard, M.; Popescu, S.; Maley, J.; Suc, J.

    2012-12-01

    Climate of the circum-Atlantic intertropical zone is driven by the ocean/atmosphere dynamics in response to variations of yearly insolation. These latitudes correspond to the convergence of the Hadley cells expressed on earth surface by intense trade winds and in lower troposphere by the African easterly jet making the edges of the intertropical zone relatively dry, while humidity is concentrated near the Equator. This phenomenon generates a precipitation front, known as the InterTropical Convergence Zone (ITCZ), the oscillations of which regulate the latitudinal vegetation distribution. Pollen record of core KZai 02 (Guinea Gulf) allows high resolution reconstruction of variations of past ecosystems over Central Africa during the Last Climatic Cycle. Plant taxa recorded in pollen analyses have been clustered according to their ecological requirements and African phytogeography. Fluctuations of these groups inform on precipitation intensity and their distribution during the last 130 ka. During Glacials, an open vegetation made of Cyperaceae marshes developed in the central Zaire/Congo Basin, surrounded by savannah on borders and afromontane forests on reliefs. Composition and distribution of vegetation indicate a decrease in monsoon activity and the strengthening of the precipitation front in the center of the basin. Interglacial phases are characterized by rain forest expansion over Central Africa in response to a precipitation enhancement associated with a northward shift of the rainfall front. Replacement of afromontane forest and marsh ecosystems by savannah then lowland pioneering, warm-temperate and rain forests characterized glacial/interglacial transitions. This succession suggests the increasing influence of at least two climatic parameters: the water availability and temperature and/or CO2 fluctuation. Spectral analysis applied to vegetation groups evidences the forcing of insolation, mainly driven by precession, on the West African monsoon system. Sub

  10. Improved procedure for separation and purification of Arthronema africanum phycobiliproteins.

    PubMed

    Minkova, Kaledona; Tchorbadjieva, Magdalena; Tchernov, Aleksey; Stojanova, Margarita; Gigova, Liliana; Busheva, Mira

    2007-04-01

    A rapid, inexpensive and reliable procedure for separation and purification of C-phycocyanin (C-PC) and allophycocyanin (APC) from Arthronema africanum based on a previously described rivanol-sulfate method for C-PC purification was developed. Exclusion of NaCl from the extraction buffer resulted in complete separation of APC and C-PC, two-fold reduction of rivanol treatments, and a higher yield and purity of C-PC. Pure C-PC (A(620)/A(280) of 4.52) and APC (A(652)/A(280) of 2.41) were obtained. The estimated molecular masses of the alpha and beta subunits were 17 and 19 kDsmall a, Cyrillic for capital ES, Cyrillic-phycocyanin and 16 and 18 kDsmall a, Cyrillic for APC, respectively. The overall C-PC recovery of 55% (w/w) from its content (100 mg) in the crude extract was 10-20% higher than so far reported. The procedure appears promising for scaling up and broader applications.

  11. Tracking cashew economically important diseases in the West African region using metagenomics.

    PubMed

    Monteiro, Filipa; Romeiras, Maria M; Figueiredo, Andreia; Sebastiana, Mónica; Baldé, Aladje; Catarino, Luís; Batista, Dora

    2015-01-01

    During the last decades, agricultural land-uses in West Africa were marked by dramatic shifts in the coverage of individual crops. Nowadays, cashew (Anacardium occidentale L.) is one of the most export-oriented horticulture crops, notably in Guinea-Bissau. Relying heavily on agriculture to increase their income, developing countries have been following a strong trend of moving on from traditional farming systems toward commercial production. Emerging infectious diseases, driven either by adaptation to local conditions or inadvertent importation of plant pathogens, are able to cause tremendous cashew production losses, with economic and social impact of which, in developing countries is often underestimated. Presently, plant genomics with metagenomics as an emergent tool, presents an enormous potential to better characterize diseases by providing extensive knowledge on plant pathogens at a large scale. In this perspective, we address metagenomics as a promising genomic tool to identify cashew fungal associated diseases as well as to discriminate the causal pathogens, aiming at obtaining tools to help design effective strategies for disease control and thus promote the sustainable production of cashew in West African Region. PMID:26175748

  12. Genome-Wide Divergence in the West-African Malaria Vector Anopheles melas.

    PubMed

    Deitz, Kevin C; Athrey, Giridhar A; Jawara, Musa; Overgaard, Hans J; Matias, Abrahan; Slotman, Michel A

    2016-01-01

    Anopheles melas is a member of the recently diverged An. gambiae species complex, a model for speciation studies, and is a locally important malaria vector along the West-African coast where it breeds in brackish water. A recent population genetic study of An. melas revealed species-level genetic differentiation between three population clusters. An. melas West extends from The Gambia to the village of Tiko, Cameroon. The other mainland cluster, An. melas South, extends from the southern Cameroonian village of Ipono to Angola. Bioko Island, Equatorial Guinea An. melas populations are genetically isolated from mainland populations. To examine how genetic differentiation between these An. melas forms is distributed across their genomes, we conducted a genome-wide analysis of genetic differentiation and selection using whole genome sequencing data of pooled individuals (Pool-seq) from a representative population of each cluster. The An. melas forms exhibit high levels of genetic differentiation throughout their genomes, including the presence of numerous fixed differences between clusters. Although the level of divergence between the clusters is on a par with that of other species within the An. gambiae complex, patterns of genome-wide divergence and diversity do not provide evidence for the presence of pre- and/or postmating isolating mechanisms in the form of speciation islands. These results are consistent with an allopatric divergence process with little or no introgression. PMID:27466271

  13. Tracking cashew economically important diseases in the West African region using metagenomics

    PubMed Central

    Monteiro, Filipa; Romeiras, Maria M.; Figueiredo, Andreia; Sebastiana, Mónica; Baldé, Aladje; Catarino, Luís; Batista, Dora

    2015-01-01

    During the last decades, agricultural land-uses in West Africa were marked by dramatic shifts in the coverage of individual crops. Nowadays, cashew (Anacardium occidentale L.) is one of the most export-oriented horticulture crops, notably in Guinea-Bissau. Relying heavily on agriculture to increase their income, developing countries have been following a strong trend of moving on from traditional farming systems toward commercial production. Emerging infectious diseases, driven either by adaptation to local conditions or inadvertent importation of plant pathogens, are able to cause tremendous cashew production losses, with economic and social impact of which, in developing countries is often underestimated. Presently, plant genomics with metagenomics as an emergent tool, presents an enormous potential to better characterize diseases by providing extensive knowledge on plant pathogens at a large scale. In this perspective, we address metagenomics as a promising genomic tool to identify cashew fungal associated diseases as well as to discriminate the causal pathogens, aiming at obtaining tools to help design effective strategies for disease control and thus promote the sustainable production of cashew in West African Region. PMID:26175748

  14. Genome-Wide Divergence in the West-African Malaria Vector Anopheles melas

    PubMed Central

    Deitz, Kevin C.; Athrey, Giridhar A.; Jawara, Musa; Overgaard, Hans J.; Matias, Abrahan; Slotman, Michel A.

    2016-01-01

    Anopheles melas is a member of the recently diverged An. gambiae species complex, a model for speciation studies, and is a locally important malaria vector along the West-African coast where it breeds in brackish water. A recent population genetic study of An. melas revealed species-level genetic differentiation between three population clusters. An. melas West extends from The Gambia to the village of Tiko, Cameroon. The other mainland cluster, An. melas South, extends from the southern Cameroonian village of Ipono to Angola. Bioko Island, Equatorial Guinea An. melas populations are genetically isolated from mainland populations. To examine how genetic differentiation between these An. melas forms is distributed across their genomes, we conducted a genome-wide analysis of genetic differentiation and selection using whole genome sequencing data of pooled individuals (Pool-seq) from a representative population of each cluster. The An. melas forms exhibit high levels of genetic differentiation throughout their genomes, including the presence of numerous fixed differences between clusters. Although the level of divergence between the clusters is on a par with that of other species within the An. gambiae complex, patterns of genome-wide divergence and diversity do not provide evidence for the presence of pre- and/or postmating isolating mechanisms in the form of speciation islands. These results are consistent with an allopatric divergence process with little or no introgression. PMID:27466271

  15. [Health consequences of the tobacco epidemic in West African French-speaking countries and current tobacco control].

    PubMed

    da Costa e Silva, Vera Luiza

    2005-01-01

    The burden of disease due to tobacco for each country will depend on the prevalence of tobacco use and the duration of the epidemic. Given that the tobacco epidemic in West African Francophone countries is relatively recent, the burden of disease due to tobacco use is currently low. However, tobacco related burden of disease in Francophone West African countries is increasing as the number of smokers continues to increase and the population has been smoking for a longer period of time. If the current trends continue, West African countries will be suffering the massive consequences of tobacco use in two or three decades. Apart from the classical health consequences of tobacco consumption such as certain types of cancer and cardiovascular diseases, there are some conditions of special importance in low income African countries such as the increased risk of tuberculosis infection and mortality amongst smokers, low birth weight for babies of smoking mothers, and tobacco consumption associated malnutrition especially amongst women. Furthermore, developing countries, with inadequate resources and other important health issues, cannot afford the costs of the chronic degenerating conditions caused by tobacco use, as these are very expensive to treat. Tobacco control in Francophone African countries is still deficient Human and financial resources which are often scarce in West African countries are dedicated to other health issues since tobacco is normally not amongst the public health priorities. Legislation in Francophone African countries is limited and not adequately enforced. A major reason for governments' inaction on tobacco is their fear of creating unemployment and loss of revenue from tobacco taxes. This fear is derived mainly from the arguments of the tobacco industry. Apart from lobbying governments, the tobacco industry uses all kinds of strategies to market their products in these countries and faces practically no barriers to their business in these

  16. Feedback of observed interannual vegetation change: a regional climate model analysis for the West African monsoon

    NASA Astrophysics Data System (ADS)

    Klein, Cornelia; Bliefernicht, Jan; Heinzeller, Dominikus; Gessner, Ursula; Klein, Igor; Kunstmann, Harald

    2016-06-01

    West Africa is a hot spot region for land-atmosphere coupling where atmospheric conditions and convective rainfall can strongly depend on surface characteristics. To investigate the effect of natural interannual vegetation changes on the West African monsoon precipitation, we implement satellite-derived dynamical datasets for vegetation fraction (VF), albedo and leaf area index into the Weather Research and Forecasting model. Two sets of 4-member ensembles with dynamic and static land surface description are used to extract vegetation-related changes in the interannual difference between August-September 2009 and 2010. The observed vegetation patterns retain a significant long-term memory of preceding rainfall patterns of at least 2 months. The interannual vegetation changes exhibit the strongest effect on latent heat fluxes and associated surface temperatures. We find a decrease (increase) of rainy hours over regions with higher (lower) VF during the day and the opposite during the night. The probability that maximum precipitation is shifted to nighttime (daytime) over higher (lower) VF is 12 % higher than by chance. We attribute this behaviour to horizontal circulations driven by differential heating. Over more vegetated regions, the divergence of moist air together with lower sensible heat fluxes hinders the initiation of deep convection during the day. During the night, mature convective systems cause an increase in the number of rainy hours over these regions. We identify this feedback in both water- and energy-limited regions of West Africa. The inclusion of observed dynamical surface information improved the spatial distribution of modelled rainfall in the Sahel with respect to observations, illustrating the potential of satellite data as a boundary constraint for atmospheric models.

  17. Incidence of pregnancy following antiretroviral therapy initiation and associated factors in eight West African countries

    PubMed Central

    Burgos-Soto, Juan; Balestre, Eric; Minga, Albert; Ajayi, Samuel; Sawadogo, Adrien; Zannou, Marcel D.; Leroy, Valériane; Ekouevi, Didier K.; Dabis, François; Becquet, Renaud

    2014-01-01

    Introduction This study aimed at estimating the incidence of pregnancy after antiretroviral therapy (ART) initiation in eight West African countries over a 10-year period. Methods A retrospective analysis was conducted within the international database of the IeDEA West Africa Collaboration. All HIV-infected women aged <50 years and starting ART for their own health between 1998 and 2011 were eligible. Pregnancy after ART initiation was the main outcome and was based on clinical reporting. Poisson regression analysis accounting for country heterogeneity was computed to estimate first pregnancy incidence post-ART and to identify its associated factors. Pregnancy incidence rate ratios were adjusted on country, baseline CD4 count and clinical stage, haemoglobin, age, first ART regimen and calendar year. Results Overall 29,425 HIV-infected women aged 33 years in median [Inter Quartile Range: 28–38] contributed for 84,870 women-years of follow-up to this analysis. The crude incidence of first pregnancy (2,304 events) was 2.9 per 100 women-years [95% confidence interval [CI]: 2.7–3.0], the highest rate being reported among women aged 25–29 years: 4.7 per 100 women-years; 95% CI: 4.3–5.1. The overall Kaplan-Meier probability of pregnancy occurrence by the fourth year on ART was 10.9% (95% CI: 10.4–11.4) and as high as 28.4% (95% CI: 26.3–30.6) among women aged 20–29 years at ART initiation. Conclusion The rate of pregnancy occurrence after ART initiation among HIV-infected women living in the West Africa region was high. Family planning services tailored to procreation needs should be provided to all HIV-infected women initiating ART and health consequences carefully monitored in this part of the world. PMID:25216079

  18. The West African Monsoon: variability and teleconnection with ENSO during the years 1948-57

    NASA Astrophysics Data System (ADS)

    Stickler, Alexander; Brönnimann, Stefan

    2010-05-01

    The intensity of the West African Monsoon (WAM) has been shown to be influenced by different factors. Most important for the existence of the monsoon system is the land-sea thermal contrast between the North African landmass and the Gulf of Guinea. ENSO plays an important role for its interannual variability via an atmospheric teleconnection bridging the Pacific and Atlantic oceanic basins and favouring either descent/weak low-level monsoon flow or ascent/strong low-level monsoon flow over tropical West Africa. Most published studies on the WAM variability are based on reanalysis datasets. However, while reproducing quite well the interannual variability, reanalysis products have been found to contain major biases in certain tropical regions before 1968. These lead to an unrealistic low frequency behaviour and might be explained by the lack of observations assimilated into the reanalyses, as is the case e.g. for tropical Africa where only the much sparser radiosonde data have been assimilated into the NCEP/NCAR Reanalysis (NNR). Here we present an analysis of the interannual WAM variability and its teleconnection with ENSO for the years 1948-57 which is not based on a reanalysis, but on early pilot balloon observational wind data from the Comprehensive Historical Upper Air Network (CHUAN). We have examined wind data from all 36 stations located in the domain (10°S-30°N, 20°W-20°E) on 5 levels up to the mid troposphere (corresponding roughly to the 925, 850, 700, 600 and 500 hPa pressure levels). This analysis shows that 7 subregions can be defined which are characterised by similar vertical wind profiles as well as seasonality: the NW (Mauritania, northern Senegal), the SW (southern Senegal to coastal Guinea), central sub-Saharan West Africa (SSWA, from interior Guinea in the W to coastal Cameroon and southern Niger in the E), central and eastern Niger, western Chad, the western Central African Republic, and the southern coastal regions east of the Gulf of

  19. Extracts from Pygeum africanum and other ethnobotanical species with antiandrogenic activity.

    PubMed

    Schleich, Sonja; Papaioannou, Maria; Baniahmad, Aria; Matusch, Rudolf

    2006-07-01

    Extracts from Pygeum africanum, Serenoa repens and Cucurbita pepo are used in the treatment of benign prostatic hyperplasia (BPH) and prostate cancer (PCa). The activity of the androgen receptor (AR) is known to control growth of the prostate. Here, we examined extracts of these plants for their antiandrogenic activity using an AR responsive reporter gene assay for drug discovery. A selective dichloromethane extract from the stem barks of Pygeum africanum revealed the highest antiandrogenic effect. Bioactivity-directed fractionation of this extract led to the isolation of N-butylbenzenesulfonamide (NBBS) indicating that extracts of the stem bark of P. africanum harbour androgen antagonistic activity. This compound may provide a novel approach for the prevention and treatment of BPH and human PCa.

  20. Renin angiotensinogen system gene polymorphisms and essential hypertension among people of West African descent: a systematic review.

    PubMed

    Reiter, L M; Christensen, D L; Gjesing, A P

    2016-08-01

    This systematic review investigates the high level of hypertension found among urban dwellers in West Africa and in the West African Diaspora in the Americas in relation to variants within the genes encoding the renin angiotensinogen system. For comparison, the results from the Caucasian populations are reviewed as well. Through a PubMed search, 1252 articles were identified and 28 eligible articles assessed in detail of which 13 included a Caucasian population. The results suggest that among the people of West African descent and among the people of Caucasian descent, hypertension is partly related to a number of single nucleotide polymorphisms (SNPs) and haplotypes in the renin gene, the angiotensinogen gene, the angiotensinogen I-converting enzyme gene and the angiotensinogen II type 1 receptor gene. Concordance between these two populations was found for some SNPs. However, for others, it was found that the SNPs associating with hypertension and the disease allele frequencies differed between these populations. Understanding the importance of these variants in a modern life setting may assist our understanding of the increased risk of developing hypertension among West Africans. Because of inconsistency in the results, low statistical power and methodological differences between studies, these results can only be taken as indicative of an association.

  1. West African monsoon decadal variability and surface-related forcings: second West African Monsoon Modeling and Evaluation Project Experiment (WAMME II)

    NASA Astrophysics Data System (ADS)

    Xue, Yongkang; De Sales, Fernando; Lau, William K.-M.; Boone, Aaron; Kim, Kyu-Myong; Mechoso, Carlos R.; Wang, Guiling; Kucharski, Fred; Schiro, Kathleen; Hosaka, Masahiro; Li, Suosuo; Druyan, Leonard M.; Sanda, Ibrah Seidou; Thiaw, Wassila; Zeng, Ning; Comer, Ruth E.; Lim, Young-Kwon; Mahanama, Sarith; Song, Guoqiong; Gu, Yu; Hagos, Samson M.; Chin, Mian; Schubert, Siegfried; Dirmeyer, Paul; Ruby Leung, L.; Kalnay, Eugenia; Kitoh, Akio; Lu, Cheng-Hsuan; Mahowald, Natalie M.; Zhang, Zhengqiu

    2016-06-01

    The second West African Monsoon Modeling and Evaluation Project Experiment (WAMME II) is designed to improve understanding of the possible roles and feedbacks of sea surface temperature (SST), land use land cover change (LULCC), and aerosols forcings in the Sahel climate system at seasonal to decadal scales. The project's strategy is to apply prescribed observationally based anomaly forcing, i.e., "idealized but realistic" forcing, in simulations by climate models. The goal is to assess these forcings' effects in producing/amplifying seasonal and decadal climate variability in the Sahel between the 1950s and the 1980s, which is selected to characterize the great drought period of the last century. This is the first multi-model experiment specifically designed to simultaneously evaluate such relative contributions. The WAMME II models have consistently demonstrated that SST forcing is a major contributor to the twentieth century Sahel drought. Under the influence of the maximum possible SST forcing, the ensemble mean of WAMME II models can produce up to 60 % of the precipitation difference during the period. The present paper also addresses the role of SSTs in triggering and maintaining the Sahel drought. In this regard, the consensus of WAMME II models is that both Indian and Pacific Ocean SSTs greatly contributed to the drought, with the former producing an anomalous displacement of the Intertropical Convergence Zone before the WAM onset, and the latter mainly contributes to the summer WAM drought. The WAMME II models also show that the impact of LULCC forcing on the Sahel climate system is weaker than that of SST forcing, but still of first order magnitude. According to the results, under LULCC forcing the ensemble mean of WAMME II models can produces about 40 % of the precipitation difference between the 1980s and the 1950s. The role of land surface processes in responding to and amplifying the drought is also identified. The results suggest that catastrophic

  2. The Ebola threat: China's response to the West African epidemic and national development of prevention and control policies and infrastructure.

    PubMed

    Fan, Hao-Jun; Gao, Hong-Wei; Ding, Hui; Zhang, Bi-Ke; Hou, Shi-Ke

    2015-02-01

    There is growing concern in West Africa about the spread of the Ebola hemorrhagic fever virus. With the increasing global public health risk, a coordinated international response is necessary. The Chinese government is prepared to work in collaboration with West African countries to assist in the containment and control of the epidemic through the contribution of medical expertise and mobile laboratory testing teams. Nationally, China is implementing prevention programs in major cities and provinces, the distribution of Ebola test kits, and the deployment of a new national Ebola research laboratory.

  3. The Ebola threat: China's response to the West African epidemic and national development of prevention and control policies and infrastructure.

    PubMed

    Fan, Hao-Jun; Gao, Hong-Wei; Ding, Hui; Zhang, Bi-Ke; Hou, Shi-Ke

    2015-02-01

    There is growing concern in West Africa about the spread of the Ebola hemorrhagic fever virus. With the increasing global public health risk, a coordinated international response is necessary. The Chinese government is prepared to work in collaboration with West African countries to assist in the containment and control of the epidemic through the contribution of medical expertise and mobile laboratory testing teams. Nationally, China is implementing prevention programs in major cities and provinces, the distribution of Ebola test kits, and the deployment of a new national Ebola research laboratory. PMID:25563862

  4. The Mid-Holocene West African Monsoon strength modulated by Saharan dust and vegetation

    NASA Astrophysics Data System (ADS)

    Pausata, F. S. R.; Messori, G.; Zhang, Q.

    2015-12-01

    The West African Monsoon (WAM) is crucial for the socio-economic stability of millions of people living in the Sahel. Severe droughts have ravaged the region in the last three decades of the 20th century, highlighting the need for a better understanding of the WAM dynamics. One of the most dramatic changes in the WAM occurred between 15,000-5,000 years BP, when increased summer precipitation led to the so-called "Green Sahara" and to a reduction in dust emissions from the region. Previous studies have shown that variations in vegetation and soil type can have major impacts on precipitation. However, model simulations are still unable to fully reproduce the intensification and geographical expansion of the African monsoon during that period, even when vegetation over the Sahara is simulated. Here, we use a fully coupled simulation for 6000 years BP in which prescribed Saharan vegetation and dust concentrations are changed in turn. A close agreement with proxy records is obtained only when both Saharan vegetation and dust decrease are taken into account (Fig. 1). The dust reduction extends the monsoon's northern limit further than the vegetation-change case only (Fig. 2), by strengthening vegetation-albedo feedbacks and driving a deeper Saharan Heat Low. The dust reduction under vegetated Sahara conditions leads to a northward shift of the WAM extension that is about twice as large as the shift due to the changes in orbital forcing alone. We therefore conclude that accounting for changes in Saharan dust loadings is essential for improving model simulations of the MH WAM. The role of dust is also relevant when looking into the future, since Saharan dust emission may decrease owing to both direct and indirect anthropogenic impacts on land cover.

  5. West African Monsoon dynamics in idealized simulations: the competitive roles of SST warming and CO2

    NASA Astrophysics Data System (ADS)

    Gaetani, Marco; Flamant, Cyrille; Hourdin, Frederic; Bastin, Sophie; Braconnot, Pascale; Bony, Sandrine

    2015-04-01

    The West African Monsoon (WAM) is affected by large climate variability at different timescales, from interannual to multidecadal, with strong environmental and socio-economic impacts associated to climate-related rainfall variability, especially in the Sahelian belt. State-of-the-art coupled climate models still show poor ability in correctly simulating the WAM past variability and also a large spread is observed in future climate projections. In this work, the July-to-September (JAS) WAM variability in the period 1979-2008 is studied in AMIP-like simulations (SST-forced) from CMIP5. The individual roles of global SST warming and CO2 concentration increasing are investigated through idealized experiments simulating a 4K warmer SST and a 4x CO2 concentration, respectively. Results show a dry response in Sahel to SST warming, with dryer conditions over western Sahel. On the contrary, wet conditions are observed when CO2 is increased, with the strongest response over central-eastern Sahel. The precipitation changes are associated to modifications in the regional atmospheric circulation: dry (wet) conditions are associated with reduced (increased) convergence in the lower troposphere, a southward (northward) shift of the African Easterly Jet, and a weaker (stronger) Tropical Easterly Jet. The co-variability between global SST and WAM precipitation is also investigated, highlighting a reorganization of the main co-variability modes. Namely, in the 4xCO2 simulation the influence of Tropical Pacific is dominant, while it is reduced in the 4K simulation, which also shows an increased coupling with the eastern Pacific and the Indian Ocean. The above results suggest a competitive action of SST warming and CO2 increasing on the WAM climate variability, with opposite effects on precipitation. The combination of the observed positive and negative response in precipitation, with wet conditions in central-eastern Sahel and dry conditions in western Sahel, is consistent with the

  6. The first endemic West African vertebrate family – a new anuran family highlighting the uniqueness of the Upper Guinean biodiversity hotspot

    PubMed Central

    2014-01-01

    Background Higher-level systematics in amphibians is relatively stable. However, recent phylogenetic studies of African torrent-frogs have uncovered high divergence in these phenotypically and ecologically similar frogs, in particular between West African torrent-frogs versus Central (Petropedetes) and East African (Arthroleptides and Ericabatrachus) lineages. Because of the considerable molecular divergence, and external morphology of the single West African torrent-frog species a new genus was erected (Odontobatrachus). In this study we aim to clarify the systematic position of West African torrent-frogs (Odontobatrachus). We determine the relationships of torrent-frogs using a multi-locus, nuclear and mitochondrial, dataset and include genera of all African and Asian ranoid families. Using micro-tomographic scanning we examine osteology and external morphological features of West African torrent-frogs to compare them with other ranoids. Results Our analyses reveal Petropedetidae (Arthroleptides, Ericabatrachus, Petropedetes) as the sister taxon of the Pyxicephalidae. The phylogenetic position of Odontobatrachus is clearly outside Petropedetidae, and not closely related to any other ranoid family. According to our time-tree estimation Odontobatrachus has been separated from other frog lineages since the Cretaceous (90.1 Ma; confidence interval: 84.2-97.1 Ma). Along with this molecular evidence, osteological and external diagnostic characters recognize West African torrent-frogs as distinct from other ranoids and provide strong support for the necessity of the recognition of a new family of frogs. This is the only endemic vertebrate family occurring in the Upper Guinea biodiversity hotspot. Conclusion Based on molecular and morphological distinctiveness, the West African torrent-frog Odontobatrachus natator is allocated to a newly described anuran family. The discovery of an endemic vertebrate family in West Africa highlights the Upper Guinean forests as an

  7. Optical dating of aeolian dynamism on the West African Sahelian margin

    NASA Astrophysics Data System (ADS)

    Stokes, S.; Bailey, R. M.; Fedoroff, N.; O'Marah, K. E.

    2004-04-01

    The Sahelian Margin of West Africa is widely recognised as an area of recent environmental catastrophe and human suffering arising from food shortage and land degradation associated with prolonged drought. The propensity of this region to suffer drought has been related, using environmental data collected during the period of instrumental records, to a combination of low mean annual rainfall levels and a high degree of rainfall variability which relates to sea surface temperature anomalies in the adjacent tropical Atlantic Ocean. Despite the significant environmental and human consequences of such droughts, there is a paucity of long-term environmental data for the West African Sahel. Aeolian dune reactivations in this area are a potentially highly useful environmental archive of past periods of extended drought conditions, which may have resulted in localised or widespread dune reactivation. Here we describe the initial results from an ongoing programme of research, which seeks to develop a detailed record of past dune reactivations in Mali. We find evidence for repeated Holocene dune reactivation events and a significant number of reactivations, which commenced at the time of onset of the last major drought cycle in the early 1970s. We obtain ages as young as 20-30 years for some significant dune units (thickness up to 1 m) and describe the results of experiments which test the performance of our dating exercise. We specifically test for the significance of preheat temperature on single aliquot regeneration (SAR) equivalent dose determinations and recycling ratios; neither are found vary significantly as a function of preheating. Optical dating of sand sized quartz could provide a useful tool for palaeogeographical mapping of ancient and historical dune reactivations in this region and elsewhere.

  8. Effects of high ambient temperatures on the metabolism of West African dwarf goats. II

    NASA Astrophysics Data System (ADS)

    Montsma, G.; Luiting, P.; Verstegen, M. W. A.; van der Hel, W.; Hofs, P.; Zijlker, J. W.

    1985-03-01

    32 West African dwarf goats were exposed in respiration chambers to temperature treatments of 20, 25, 30, 35, 35, 35, 30, 25, 20°C. Each treatment lasted three days. 16 goats were kept in individual pens (“I”); the others in two group pens of eight animals each (“G”). During each treatment, heat production and activity were recorded continuously over 48 hours. In addition, feed and water intake, rectal temperature, skin temperature and respiratory rate were measured during each treatment. Compared to 20°C, at 35°C rectal temperature increased from 39.0°C to 39.9°C, respiratory rate from 30 to 260 times. min-1 and skin temperature from 37.1°C to 39.5°C. Hay intake decreased by 40%; concentrates (30 g. kg-0.75. d-1) were always completely consumed. Heat production was higher for the “G” animals at 20°C and higher for the “I” animals at 35°C. These differences in heat production between the two groups were reflected in differences in rectal and skin temperature and in respiratory rate but only very slightly in differences in hay intake. Tissue insulation was 0.014 K. m2. W-1 at 30°C and 35°C and 0.022 K. m2. W-1 at 20°C. It is concluded that the reactions of these dwarf goats to high ambient temperatures are not different in principle from those of other domestic ruminants and that they do not exhibit a specific suitability or unsuitability for ambient temperatures as prevailing in West Africa.

  9. Variability of West African monsoon patterns generated by a WRF multi-physics ensemble

    NASA Astrophysics Data System (ADS)

    Klein, Cornelia; Heinzeller, Dominikus; Bliefernicht, Jan; Kunstmann, Harald

    2015-11-01

    The credibility of regional climate simulations over West Africa stands and falls with the ability to reproduce the West African monsoon (WAM) whose precipitation plays a pivotal role for people's livelihood. In this study, we simulate the WAM for the wet year 1999 with a 27-member multi-physics ensemble of the Weather Research and Forecasting (WRF) model. We investigate the inter-member differences in a process-based manner in order to extract generalizable information on the behavior of the tested cumulus (CU), microphysics (MP), and planetary boundary layer (PBL) schemes. Precipitation, temperature and atmospheric dynamics are analyzed in comparison to the Tropical Rainfall Measuring Mission (TRMM) rainfall estimates, the Global Precipitation Climatology Centre (GPCC) gridded gauge-analysis, the Global Historical Climatology Network (GHCN) gridded temperature product and the forcing data (ERA-Interim) to explore interdependencies of processes leading to a certain WAM regime. We find that MP and PBL schemes contribute most to the ensemble spread (147 mm month-1) for monsoon precipitation over the study region. Furthermore, PBL schemes have a strong influence on the movement of the WAM rainband because of their impact on the cloud fraction, that ranges from 8 to 20 % at 600 hPa during August. More low- and mid-level clouds result in less incoming radiation and a weaker monsoon. Ultimately, we identify the differing intensities of the moist Hadley-type meridional circulation that connects the monsoon winds to the Tropical Easterly Jet as the main source for inter-member differences. The ensemble spread of Sahel precipitation and associated dynamics for August 1999 is comparable to the observed inter-annual spread (1979-2010) between dry and wet years, emphasizing the strong potential impact of regional processes and the need for a careful selection of model parameterizations.

  10. Estimation of freshwater availability in the West African sub-continent using the SWAT hydrologic model

    NASA Astrophysics Data System (ADS)

    Schuol, Jürgen; Abbaspour, Karim C.; Srinivasan, Raghavan; Yang, Hong

    2008-04-01

    SummaryAccurate knowledge of freshwater availability is indispensable for water resources management at regional or national level. This information, however, has historically been very difficult to obtain because of lack of data, difficulties in the aggregation of spatial information, and problems in the quantification of distributed hydrological processes. The currently available estimates of freshwater availability by a few large international organizations such as FAO and UNESCO are often not sufficient as they only provide aggregated rough quantities of river discharge and groundwater recharge (blue water) at a national level and on a yearly basis. This paper aims to provide a procedure to improve the estimations of freshwater availability at subbasin level and monthly intervals. Applying the distributed hydrological model "Soil and Water Assessment Tool" (SWAT), the freshwater availability is quantified for a 4-million km 2 area covering some 18 countries in West Africa. The procedure includes model calibration and validation based on measured river discharges, and quantification of the uncertainty in model outputs using "Sequential Uncertainty Fitting Algorithm" (SUFI-2) The aggregated results for 11 countries are compared with two other studies. It was seen that for most countries, the estimates from the other two studies fall within our calculated prediction uncertainty ranges. The uncertainties are, in general, within reasonable ranges but larger in subbasins containing features such as dams and wetlands, or subbasins with inadequate climate or landuse information. As the modelling procedure in this study proved quite successful, its application for quantification of freshwater availability at a global scale is already underway. There are, however, two limitations in the West African model: (1) not all the components of the water balance model such as soil moisture or deep aquifer recharge could be directly calibrated because of lack of data and (2) the

  11. Impact of climate change on vegetation dynamics in a West African river basin

    NASA Astrophysics Data System (ADS)

    Sawada, Y.; Koike, T.

    2012-12-01

    Future changes in terrestrial biomass distribution under climate change will have a tremendous impact on water availability and land productivity in arid and semi-arid regions. Assessment of future change of biomass distribution in the regional or the river basin scale is strongly needed. An eco-hydrological model that fully couples a dynamic vegetation model (DVM) with a distributed biosphere hydrological model is applied to multi-model assessment of climate change impact on vegetation dynamics in a West African river basin. In addition, a distributed and auto optimization system of parameters in DVM is developed to make it possible to model a diversity of phonologies of plants by using different parameters in the different model grids. The simple carbon cycle modeling in a distributed hydrological model shows reliable accuracy in simulating the seasonal cycle of vegetation on the river basin scale. Model outputs indicate that generally, an extension of dry season duration and surface air temperature rising caused by climate change may cause a dieback of vegetation in West Africa. However, we get different seasonal and spatial changes of leaf area index and different mechanisms of the degradation when we used different general circulation models' outputs as meteorological forcing of the eco-hydrological model. Therefore, multi-model analysis like this study is important to deliver meaningful information to the society because we can discuss the uncertainties of our prediction by this methodology. This study makes it possible to discuss the impact of future change of terrestrial biomass on climate and water resources in the regional or the river basin scale although we need further sophistications of the system. Performance of the eco-hydrological model (WEB-DHM+DVM) in Volta River Basin, with basin-averaged leaf area index from model (blue solid line) and AVHRR satellite-derived product (red rectangles).

  12. Strengthening malaria prevention and control: integrating West African militaries' malaria control efforts. The inaugural meeting of the West African Malaria Task Force, April 24-26, 2013, Accra, Ghana.

    PubMed

    McCollum, Jeffrey T; Hanna, Refaat; Halbach, Alaina C; Cummings, James F

    2015-01-01

    From April 24 to 26, 2013, the Armed Forces Health Surveillance Center and the U.S. Africa Command cosponsored the inaugural meeting of the West Africa Malaria Task Force in Accra, Ghana. The meeting's purpose was to identify common challenges, explore regional and transcontinental collaborations, and to share knowledge about best practices in the fight against malaria in West Africa. Military representatives from Benin, Burkina Faso, Ghana, Liberia, Niger, Nigeria, Senegal, and Togo participated in the Task Force; various U.S. Government agencies were also represented, including the Department of Defense, the Centers for Disease Control and Prevention, and the Agency for International Development. African nation participants presented brief overviews of their military's malaria prevention and control measures, surveillance programs, diagnostic capabilities, and treatment regimens emphasizing gaps within existing programs. Representatives from U.S. agencies discussed activities and capabilities relevant for the region, challenges and lessons learned regarding malaria, and highlighted opportunities for enhanced partnerships to counter malaria in West Africa. This article summarizes the major conclusions of the Task Force meeting, identifies relevant focus areas for future Task Force activities, and outlines opportunities for further inclusion of West African militaries to improve regional malaria surveillance and control efforts.

  13. Determinants of suboptimal complementary feeding practices among children aged 6-23 months in four anglophone West African countries.

    PubMed

    Issaka, Abukari I; Agho, Kingsley E; Page, Andrew N; Burns, Penelope L; Stevens, Garry J; Dibley, Michael J

    2015-10-01

    Suboptimal complementary feeding practices have a detrimental impact on a child's growth, health and development in the first two years of life. They lead to child malnutrition, which contributes to the high prevalence of stunting (38%) and underweight (28%) reported for children <5 years of age in Sub-Saharan Africa. This study analysed complementary feeding practices in four anglophone West African countries (Ghana, Liberia, Nigeria and Sierra Leone) using the most recent Demographic and Health Surveys. The study covered 12 623 children aged 6-23 months from four anglophone West African countries (Ghana: 822 children: Liberia: 1458 children, Nigeria: 8786 children and Sierra Leone: 1557 children). Four complementary feeding indicators were examined against a set of individual-, household- and community-level factors, using multiple regression analysis. Multivariate analyses found that lack of post-natal contacts with health workers, maternal illiteracy and geographical region were common determinants of delayed introduction of solid, semi-solid or soft foods across all four countries. Predictors for minimum dietary diversity, minimum meal frequency and minimum acceptable diet included children aged 6-11 months, administrative/geographical region, poorer household income and limited access to media. The authors recommend that the four anglophone West African countries studied should prioritise efforts to improve complementary feeding practices in order to reduce child morbidity and mortality. Interventional studies on complementary feeding should target those from poor and illiterate households.

  14. Population Structure of Clinical Pseudomonas aeruginosa from West and Central African Countries

    PubMed Central

    Cholley, Pascal; Ka, Roughyatou; Guyeux, Christophe; Thouverez, Michelle; Guessennd, Nathalie; Ghebremedhin, Beniam; Frank, Thierry; Bertrand, Xavier; Hocquet, Didier

    2014-01-01

    Background Pseudomonas aeruginosa (PA) has a non-clonal, epidemic population with a few widely distributed and frequently encountered sequence types (STs) called ‘high-risk clusters’. Clinical P. aeruginosa (clinPA) has been studied in all inhabited continents excepted in Africa, where a very few isolates have been analyzed. Here, we characterized a collection of clinPA isolates from four countries of West and Central Africa. Methodology 184 non-redundant isolates of clinPA from hospitals of Senegal, Ivory Coast, Nigeria, and Central African Republic were genotyped by MLST. We assessed their resistance level to antibiotics by agar diffusion and identified the extended-spectrum β-lactamases (ESBLs) and metallo-β-lactamases (MBLs) by sequencing. The population structure of the species was determined by a nucleotide-based analysis of the entire PA MLST database and further localized on the phylogenetic tree (i) the sequence types (STs) of the present collection, (ii) the STs by continents, (iii) ESBL- and MBL-producing STs from the MLST database. Principal Findings We found 80 distinct STs, of which 24 had no relationship with any known STs. ‘High-risk’ international clonal complexes (CC155, CC244, CC235) were frequently found in West and Central Africa. The five VIM-2-producing isolates belonged to CC233 and CC244. GES-1 and GES-9 enzymes were produced by one CC235 and one ST1469 isolate, respectively. We showed the spread of ‘high-risk’ international clonal complexes, often described as multidrug-resistant on other continents, with a fully susceptible phenotype. The MBL- and ESBL-producing STs were scattered throughout the phylogenetic tree and our data suggest a poor association between a continent and a specific phylogroup. Conclusions ESBL- and MBL-encoding genes are borne by both successful international clonal complexes and distinct local STs in clinPA of West and Central Africa. Furthermore, our data suggest that the spread of a ST could be

  15. Exploring child prostitution in a major city in the West African region.

    PubMed

    Hounmenou, Charles

    2016-09-01

    The study explored the characteristics of child prostitution in a major city in the West African region. A convenience sample of children in prostitution, specifically girls below age 18 (n=243), were recruited on 83 prostitution sites identified in Ouagadougou, the capital city of Burkina Faso. A survey instrument, consisting of 71 closed-ended question items, was used to explore various variables including profile of children in prostitution, factors of vulnerability to prostitution; prostitution practices, compensations and related issues in child prostitution. The findings show that most children in prostitution in the city were from Burkina Faso (63%) and Nigeria (30%), two countries that do not share borders. Most native respondents practiced prostitution for survival and to support their families. In contrast, all the respondents from Nigeria practiced prostitution as victims of international sex trafficking. An important finding was that 77% of the children in prostitution surveyed were educated. Among the respondents, there were similarities in the major life events that contributed to their situation of prostitution. These life events include early separation with parents, sexual abuse, foster care, and forced marriage. Implications for policy, practice and research are discussed. PMID:27490517

  16. Changing causes of death in the West African town of Banjul, 1942-97.

    PubMed Central

    van der Sande, M. A.; Inskip, H. M.; Jaiteh, K. O.; Maine, N. P.; Walraven, G. E.; Hall, A. J.; McAdam, K. P.

    2001-01-01

    OBJECTIVE: To determine trends in the causes of death in a West African town. Mortality caused by infectious diseases is reported to be declining while degenerative and man-made mortality factors are increasingly significant. Most mortality analyses for sub-Saharan Africa have involved extrapolation and have not been derived from community-based data. METHODS: Historical data on causes of death coded by physicians were analysed for the urban population of Banjul for the period 1942-97. As the calculation of rates is not possible in the absence of a reliable population denominator, age-standardized proportional mortality ratios (PMRs) for men and women by major groups of causes of death were calculated, using the 1942-49 data for reference purposes. FINDINGS: Most deaths were attributable to communicable diseases. There was a shift in proportional mortality over the study period: the contribution of communicable diseases declined and that of noncommunicable diseases and injuries increased. These trends were more marked among men than women. CONCLUSION: The data illustrate that while noncommunicable diseases and injuries are emerging as important contributors to mortality in sub-Saharan Africa, communicable diseases remain significant causes of mortality and should not be neglected. PMID:11242820

  17. Comparative multivariate analysis of biometric traits of West African Dwarf and Red Sokoto goats.

    PubMed

    Yakubu, Abdulmojeed; Salako, Adebowale E; Imumorin, Ikhide G

    2011-03-01

    The population structure of 302 randomly selected West African Dwarf (WAD) and Red Sokoto (RS) goats was examined using multivariate morphometric analyses. This was to make the case for conservation, rational management and genetic improvement of these two most important Nigerian goat breeds. Fifteen morphometric measurements were made on each individual animal. RS goats were superior (P<0.05) to the WAD for the body size and skeletal proportions investigated. The phenotypic variability between the two breeds was revealed by their mutual responses in the principal components. While four principal components were extracted for WAD goats, three components were obtained for their RS counterparts with variation in the loading traits of each component for each breed. The Mahalanobis distance of 72.28 indicated a high degree of spatial racial separation in morphology between the genotypes. The Ward's option of the cluster analysis consolidated the morphometric distinctness of the two breeds. Application of selective breeding to genetic improvement would benefit from the detected phenotypic differentiation. Other implications for management and conservation of the goats are highlighted. PMID:21080228

  18. Evolution of a Paleoproterozoic “weak type” orogeny in the West African Craton (Ivory Coast)

    NASA Astrophysics Data System (ADS)

    Vidal, M.; Gumiaux, C.; Cagnard, F.; Pouclet, A.; Ouattara, G.; Pichon, M.

    2009-11-01

    The Paleoproterozoic domain of the Ivory Coast lies in the central part of the West African Craton (WAC) and is mainly constituted by TTG, greenstones, supracrustal rocks and leucogranites. A compilation of metamorphic and radiometric data highlights that: i) metamorphic conditions are rather homogeneous through the domain, without important metamorphic jumps, ii) HP-LT assemblages are absent and iii) important volumes of magmas emplaced during the overall Paleoproterozoic orogeny suggesting the occurrence of long-lived rather hot geotherms. Results of the structural analysis, focused on three areas within the Ivory Coast, suggest that the deformation is homogeneous and distributed through the Paleoproterozoic domain. In details, results of this study point out the long-lived character of vertical movements during the Eburnean orogeny with a two folds evolution. The first stage is characterized by the development of "domes and basins" geometries without any boundary tectonic forces and the second stage is marked by coeval diapiric movements and horizontal regional-scale shortening. These features suggest that the crust is affected by vertical movements during the overall orogeny. The Eburnean orogen can then be considered as an example of long-lived Paleoproterozoic "weak type" orogen.

  19. Exploring child prostitution in a major city in the West African region.

    PubMed

    Hounmenou, Charles

    2016-09-01

    The study explored the characteristics of child prostitution in a major city in the West African region. A convenience sample of children in prostitution, specifically girls below age 18 (n=243), were recruited on 83 prostitution sites identified in Ouagadougou, the capital city of Burkina Faso. A survey instrument, consisting of 71 closed-ended question items, was used to explore various variables including profile of children in prostitution, factors of vulnerability to prostitution; prostitution practices, compensations and related issues in child prostitution. The findings show that most children in prostitution in the city were from Burkina Faso (63%) and Nigeria (30%), two countries that do not share borders. Most native respondents practiced prostitution for survival and to support their families. In contrast, all the respondents from Nigeria practiced prostitution as victims of international sex trafficking. An important finding was that 77% of the children in prostitution surveyed were educated. Among the respondents, there were similarities in the major life events that contributed to their situation of prostitution. These life events include early separation with parents, sexual abuse, foster care, and forced marriage. Implications for policy, practice and research are discussed.

  20. Physical impacts of regional climate change in the West African Sahel and the question of desertification

    SciTech Connect

    Nicholson, S.E.; Ba, M.

    1997-11-01

    The question of desertification is examined in the West African Sahel region by considering various physical indicators assumed to accompany this process. The study considers only the past 14 years, since the availability of comprehensive satellite data sets. The physical indicators examined include vegetation cover, surface albedo, soil moisture, wind-borne dust, river flow, lakes, and the ratio of available moisture to vegetation growth. Vegetation cover and albedo are assessed from satellite data. Soil moisture is assessed using a surface hydrologic model. Dust is estimated from visibility measurements. The most important results are that: (1) there is no progressive change in the vegetation cover, (2) an increase of albedo as the region dries up cannot be documented, and (3) there has been a tremendous increase in wind-borne dust over the Sahel. The vegetation cover responds almost directly to rainfall and the movement of the desert boundary corresponds roughly to rainfall fluctuations. The most important meteorological effect of the drought and/or desertification in the Sahel may be the enhanced dust generation, with the region becoming a major global source of atmospheric mineral dust. 5 refs., 7 figs., 1 tab.

  1. In Vitro Activity of Selected West African Medicinal Plants against Mycobacterium ulcerans Disease.

    PubMed

    Tsouh Fokou, Patrick Valere; Kissi-Twum, Abena Adomah; Yeboah-Manu, Dorothy; Appiah-Opong, Regina; Addo, Phyllis; Tchokouaha Yamthe, Lauve Rachel; Ngoutane Mfopa, Alvine; Fekam Boyom, Fabrice; Nyarko, Alexander Kwadwo

    2016-01-01

    Buruli ulcer (BU) is the third most prevalent mycobacteriosis, after tuberculosis and leprosy. The currently recommended combination of rifampicin-streptomycin suffers from side effects and poor compliance, which leads to reliance on local herbal remedies. The objective of this study was to investigate the antimycobacterial properties and toxicity of selected medicinal plants. Sixty-five extracts from 27 plant species were screened against Mycobacterium ulcerans and Mycobacterium smegmatis, using the Resazurin Microtiter Assay (REMA). The cytotoxicity of promising extracts was assayed on normal Chang liver cells by an MTT assay. Twenty five extracts showed activity with minimal inhibitory concentration (MIC) values ranging from 16 µg/mL to 250 µg/mL against M. smegmatis, while 17 showed activity against M. ulcerans with MIC values ranging from 125 µg/mL to 250 µg/mL. In most of the cases, plant extracts with antimycobacterial activity showed no cytotoxicity on normal human liver cells. Exception were Carica papaya, Cleistopholis patens, and Polyalthia suaveolens with 50% cell cytotoxic concentrations (CC50) ranging from 3.8 to 223 µg/mL. These preliminary results support the use of some West African plants in the treatment of Buruli ulcer. Meanwhile, further studies are required to isolate and characterize the active ingredients in the extracts. PMID:27089314

  2. Long-term Variability of NorthWest African coastal upwelling

    NASA Astrophysics Data System (ADS)

    Wade, Malick; Rodríguez-Fonseca, Belen; Lazar, Alban

    2014-05-01

    The NorthWest African sea surface temperature variability can be due to changes in the coastal upwelling system, which in turn can be due to alterations in local winds, global winds induced by teleconnections and propagation of waves from wind burst in remote regions. The two last processes could be due in turn to changes in the sea surface temperature in extended regions remote from the upwelling region, as changes in Pacific SSTs associated with ENSO, or in the Equatorial Atlantic SSTs. This work demonstrates that the whole signal cannot be explained by local wind/Ekman pumping and large scale winds induced by teleconnections play an important role. Using observational data of SSTs and winds from atmospheric reanalysis, and applying different statistical technics, as correlation analysis, filtering and discriminant analysis, the different influences and its stationarity along the observational period are tested pointing to the non stationarity of El Niño influence in FMA and to other possible predictors influencing in the region.

  3. Non-Contaminating Camouflage: Multifunctional Skin Microornamentation in the West African Gaboon Viper (Bitis rhinoceros)

    PubMed Central

    Spinner, Marlene; Gorb, Stanislav N.; Balmert, Alexander; Bleckmann, Horst; Westhoff, Guido

    2014-01-01

    The West African Gaboon viper (Bitis rhinoceros) has an extraordinary coloration of pale brown and velvety black markings. The velvety black appearance is caused by a unique hierarchical surface structures which was not found on the pale brown scales. In the present study we examined the wettability of the vipeŕs scales by measuring contact angles of water droplets. Velvet black scale surfaces had high static contact angles beyond 160° and low roll-off angles below 20° indicating an outstanding superhydrophobicity. Our calculations showed that the Cassie-Baxter model describes well wettability effects for these surfaces. Self-cleaning capabilities were determined by contaminating the scales with particles and fogging them until droplets formed. Black scales were clean after fogging, while pale scales stayed contaminated. Black scales feature multifunctional structures providing not only water-repellent but also self-cleaning properties. The pattern of nanoridges can be used as a model for surface-active technical surfaces. PMID:24599379

  4. Deep-sea environment and biodiversity of the West African Equatorial margin

    NASA Astrophysics Data System (ADS)

    Sibuet, Myriam; Vangriesheim, Annick

    2009-12-01

    The long-term BIOZAIRE multidisciplinary deep-sea environmental program on the West Equatorial African margin organized in partnership between Ifremer and TOTAL aimed at characterizing the benthic community structure in relation with physical and chemical processes in a region of oil and gas interest. The morphology of the deep Congo submarine channel and the sedimentological structures of the deep-sea fan were established during the geological ZAIANGO project and helped to select study sites ranging from 350 to 4800 m water depth inside or near the channel and away from its influence. Ifremer conducted eight deep-sea cruises on board research vessels between 2000 and 2005. Standardized methods of sampling together with new technologies such as the ROV Victor 6000 and its associated instrumentation were used to investigate this poorly known continental margin. In addition to the study of sedimentary environments more or less influenced by turbidity events, the discovery of one of the largest cold seeps near the Congo channel and deep coral reefs extends our knowledge of the different habitats of this margin. This paper presents the background, objectives and major results of the BIOZAIRE Program. It highlights the work achieved in the 16 papers in this special issue. This synthesis paper describes the knowledge acquired at a regional and local scale of the Equatorial East Atlantic margin, and tackles new interdisciplinary questions to be answered in the various domains of physics, chemistry, taxonomy and ecology to better understand the deep-sea environment in the Gulf of Guinea.

  5. The Lake Bosumtwi Drilling Project: A 1 Ma West African Paleoclimate Record

    NASA Astrophysics Data System (ADS)

    Peck, J. A.; Heil, C.; King, J. W.; Scholz, C. A.; Shanahan, T. M.; Overpeck, J. T.; Fox, P. A.; Amoako, P. Y.; Forman, S. L.; Koeberl, C.; Milkereit, B.

    2005-12-01

    Lake Bosumtwi occupies a 1.07 Ma impact crater located in Ghana, West Africa centered at 06*32'N and 01*25'W. This 78 m deep, hydrologically-closed lake has a water budget extremely sensitive to the precipitation/evapotranspiration balance and is located in the path of the seasonal migration of the ITCZ. Therefore, Lake Bosumtwi is ideally situated to provide a long record of change in North African monsoon strength. In addition, the stratified water column allows for the preservation of finely-laminated sediments and the potential for high-resolution (annual) paleoclimate reconstruction. Using the GLAD800 lake drilling system, five drill sites were occupied along a water-depth transect in order to facilitate the reconstruction of the lake level history. At these five sites, a total of 14 separate holes were drilled yielding a total sediment recovery of 1,833 m. The shallow water drill sites consist of alternating laminated lacustrine mud (deepwater environment), moderately-sorted sand (nearshore beach environment) and sandy gravel (fluvial or lake marginal environments). These sediment cores and seismic reflection profiles are being used to construct a basin-wide stratigraphic framework, in order to extend further back in time the present Bosumtwi lake level histories obtained from highstand terraces and short piston cores. At a deep water site, the complete 1 Ma lacustrine stratigraphic section was recovered in 294 m deep holes that ended in impact-glass bearing, accretionary lapilli fallout representing the initial days of sedimentation. The lowermost lacustrine sediment is a bioturbated, light-gray mud with abundant gastropod shells indicating that a shallow-water oxic lake environment was established in the crater. Much of the overlying 294 m of mud is laminated thus these sediment cores will provide a unique 1 million year record of tropical African climate change. Two contrasting litholgies identified in the dated, upper part of the deep water drill hole

  6. Haemonchotolerance in West African Dwarf goats: contribution to sustainable, anthelmintics-free helminth control in traditionally managed Nigerian dwarf goats.

    PubMed

    Chiejina, Samuel N; Behnke, Jerzy M; Fakae, Barineme B

    2015-01-01

    West African Dwarf (WAD) goats are extremely important in the rural village economy of West Africa, but still little is known about their biology, ecology and capacity to cope with gastrointestinal nematode (GIN) infections. Here, we summarise the history of this breed and explain its economic importance in rural West Africa. We review recent work showing that Nigerian WAD goats are highly trypanotolerant and resist infections with Haemonchus contortus more effectively than other breeds of domestic goat (haemonchotolerance). We believe that haemonchotolerance is largely responsible for the generally low level GIN infections and absence of clinical haemonchosis in WADs under field conditions, and has contributed to the relatively successful and sustainable, anthelmintics-free, small-scale system of goat husbandry in Nigeria's humid zone, and is immunologically based and genetically controlled. If haemonchotolerance can be shown to be genetically controlled, it should be possible to exploit the underlying genes to improve GIN resistance among productive fibre and milk producing breeds of goats, most of which are highly susceptible to nematode infections. Genetic resistance to GIN and trypanosome infections would obviate the need for expensive chemotherapy, mostly unaffordable to small-holder farmers in Africa, and a significant cost of goat husbandry in more developed countries. Either introgression of resistance alleles into susceptible breeds by conventional breeding, or transgenesis could be used to develop novel parasite-resistant, but highly productive breeds, or to improve the resistance of existing breeds, benefitting the local West African rural economy as well as global caprine livestock agriculture.

  7. Above ground biomass estimation from lidar and hyperspectral airbone data in West African moist forests.

    NASA Astrophysics Data System (ADS)

    Vaglio Laurin, Gaia; Chen, Qi; Lindsell, Jeremy; Coomes, David; Cazzolla-Gatti, Roberto; Grieco, Elisa; Valentini, Riccardo

    2013-04-01

    The development of sound methods for the estimation of forest parameters such as Above Ground Biomass (AGB) and the need of data for different world regions and ecosystems, are widely recognized issues due to their relevance for both carbon cycle modeling and conservation and policy initiatives, such as the UN REDD+ program (Gibbs et al., 2007). The moist forests of the Upper Guinean Belt are poorly studied ecosystems (Vaglio Laurin et al. 2013) but their role is important due to the drier condition expected along the West African coasts according to future climate change scenarios (Gonzales, 2001). Remote sensing has proven to be an effective tool for AGB retrieval when coupled with field data. Lidar, with its ability to penetrate the canopy provides 3D information and best results. Nevertheless very limited research has been conducted in Africa tropical forests with lidar and none to our knowledge in West Africa. Hyperspectral sensors also offer promising data, being able to evidence very fine radiometric differences in vegetation reflectance. Their usefulness in estimating forest parameters is still under evaluation with contrasting findings (Andersen et al. 2008, Latifi et al. 2012), and additional studies are especially relevant in view of forthcoming satellite hyperspectral missions. In the framework of the EU ERC Africa GHG grant #247349, an airborne campaign collecting lidar and hyperspectral data has been conducted in March 2012 over forests reserves in Sierra Leone and Ghana, characterized by different logging histories and rainfall patterns, and including Gola Rainforest National Park, Ankasa National Park, Bia and Boin Forest Reserves. An Optech Gemini sensor collected the lidar dataset, while an AISA Eagle sensor collected hyperspectral data over 244 VIS-NIR bands. The lidar dataset, with a point density >10 ppm was processed using the TIFFS software (Toolbox for LiDAR Data Filtering and Forest Studies)(Chen 2007). The hyperspectral dataset, geo

  8. Blindness and Visual Impairment in an Urban West African Population: The Tema Eye Survey

    PubMed Central

    Budenz, Donald L.; Bandi, Jagadeesh R.; Barton, Keith; Nolan, Winifred; Herndon, Leon; Whiteside-de Vos, Julia; Hay-Smith, Graham; Kim, Hanna; Tielsch, James

    2012-01-01

    Objective To determine the prevalence, etiologies, and risk factors of blindness and visual impairment among persons age 40 years and older residing in an urban West African location. Design Population-based cross-sectional study. Participants Five thousand six hundred and three participants residing in Tema, Ghana. Methods Proportionate random cluster sampling was used to select participants age 40 and over living in the city of Tema. Presenting distance visual acuity was measured at 4 and 1 meters using a reduced Logarithm of the Minimum Angle of Resolution (logMAR) tumbling E chart and then with trial frame based on autorefraction. A screening examination was performed in the field on all participants. Complete clinical examination by an ophthalmologist was performed on participants with best corrected visual acuity < 20/40 or failure of any screening test. Main Outcome Measures Age- and gender-specific prevalence, causes, and risk factors for blindness (visual acuity in the better eye of < 20/400, World Health Organization definition) and visual impairment (visual acuity in the better eye of < 20/40). Results Six thousand eight hundred and six eligible participants were identified of which 5603 (82.3%) participated in the study. The mean age (±standard deviation) of participants was 52.7±10.9. The prevalence of visual impairment was 17.1% and blindness was 1.2%. After refraction and spectacle correction, the prevalence of visual impairment and blindness decreased to 6.7% and 0.75% respectively, suggesting that refractive error is the major correctable etiology of visual impairment and blindness in this population. Of 65 subjects having visual acuity < 20/400, 22 (34%) were correctable with refraction, 21 to the level of visual impairment, and one to normal. The remaining 43 (66%) had underlying pathology (19 cataract, 9 glaucoma, 3 non-glaucomatous optic neuropathy, 3 corneal opacities, 3 retinal disease, 5 undetermined) that prevented refractive correction

  9. Characteristics and phylogeny of Bacillus cereus strains isolated from Maari, a traditional West African food condiment.

    PubMed

    Thorsen, Line; Kando, Christine Kere; Sawadogo, Hagrétou; Larsen, Nadja; Diawara, Bréhima; Ouédraogo, Georges Anicet; Hendriksen, Niels Bohse; Jespersen, Lene

    2015-03-01

    Maari is a spontaneously fermented food condiment made from baobab tree seeds in West African countries. This type of product is considered to be safe, being consumed by millions of people on a daily basis. However, due to the spontaneous nature of the fermentation the human pathogen Bacillus cereus occasionally occurs in Maari. This study characterizes succession patterns and pathogenic potential of B. cereus isolated from the raw materials (ash, water from a drilled well (DW) and potash), seed mash throughout fermentation (0-96h), after steam cooking and sun drying (final product) from two production sites of Maari. Aerobic mesophilic bacterial (AMB) counts in raw materials were of 10(5)cfu/ml in DW, and ranged between 6.5×10(3) and 1.2×10(4)cfu/g in potash, 10(9)-10(10)cfu/g in seed mash during fermentation and 10(7) - 10(9) after sun drying. Fifty three out of total 290 AMB isolates were identified as B. cereus sensu lato by use of ITS-PCR and grouped into 3 groups using PCR fingerprinting based on Escherichia coli phage-M13 primer (M13-PCR). As determined by panC gene sequencing, the isolates of B. cereus belonged to PanC types III and IV with potential for high cytotoxicity. Phylogenetic analysis of concatenated sequences of glpF, gmk, ilvD, pta, pur, pycA and tpi revealed that the M13-PCR group 1 isolates were related to B. cereus biovar anthracis CI, while the M13-PCR group 2 isolates were identical to cereulide (emetic toxin) producing B. cereus strains. The M13-PCR group 1 isolates harboured poly-γ-D-glutamic acid capsule biosynthesis genes capA, capB and capC showing 99-100% identity with the environmental B. cereus isolate 03BB108. Presence of cesB of the cereulide synthetase gene cluster was confirmed by PCR in M13-PCR group 2 isolates. The B. cereus harbouring the cap genes were found in potash, DW, cooking water and at 8h fermentation. The "emetic" type B. cereus were present in DW, the seed mash at 48-72h of fermentation and in the final product

  10. Biodiversity Mapping in a Tropical West African Forest with Airborne Hyperspectral Data

    PubMed Central

    Vaglio Laurin, Gaia; Chan, Jonathan Cheung-Wai; Chen, Qi; Lindsell, Jeremy A.; Coomes, David A.; Guerriero, Leila; Frate, Fabio Del; Miglietta, Franco; Valentini, Riccardo

    2014-01-01

    Tropical forests are major repositories of biodiversity, but are fast disappearing as land is converted to agriculture. Decision-makers need to know which of the remaining forests to prioritize for conservation, but the only spatial information on forest biodiversity has, until recently, come from a sparse network of ground-based plots. Here we explore whether airborne hyperspectral imagery can be used to predict the alpha diversity of upper canopy trees in a West African forest. The abundance of tree species were collected from 64 plots (each 1250 m2 in size) within a Sierra Leonean national park, and Shannon-Wiener biodiversity indices were calculated. An airborne spectrometer measured reflectances of 186 bands in the visible and near-infrared spectral range at 1 m2 resolution. The standard deviations of these reflectance values and their first-order derivatives were calculated for each plot from the c. 1250 pixels of hyperspectral information within them. Shannon-Wiener indices were then predicted from these plot-based reflectance statistics using a machine-learning algorithm (Random Forest). The regression model fitted the data well (pseudo-R2 = 84.9%), and we show that standard deviations of green-band reflectances and infra-red region derivatives had the strongest explanatory powers. Our work shows that airborne hyperspectral sensing can be very effective at mapping canopy tree diversity, because its high spatial resolution allows within-plot heterogeneity in reflectance to be characterized, making it an effective tool for monitoring forest biodiversity over large geographic scales. PMID:24937407

  11. Fire Patterns and Drivers of Fires in the West African Tropical Forest

    NASA Astrophysics Data System (ADS)

    Dwomoh, F. K.; Wimberly, M. C.

    2015-12-01

    The West African tropical forest (referred to as the Upper Guinean forest, UGF), is a global biodiversity hotspot providing vital ecosystem services for the region's socio-economic and environmental wellbeing. It is also one of the most fragmented and human-modified tropical forest ecosystems, with the only remaining large patches of original forests contained in protected areas. However, these remnant forests are susceptible to continued fire-mediated degradation and forest loss due to intense climatic, demographic and land use pressures. We analyzed human and climatic drivers of fire activity in the sub-region to better understand the spatial and temporal patterns of these risks. We utilized MODIS active fire and burned area products to identify fire activity within the sub-region. We measured climatic variability using TRMM rainfall data and derived indicators of human land use from a variety of geospatial datasets. We used a boosted regression trees model to determine the influences of predictor variables on fire activity. Our analyses indicated that the spatial and temporal variability of precipitation is a key driving factor of fire activity in the UGF. Anthropogenic effects on fire activity in the area were evident through the influences of agriculture and low-density populations. These human footprints in the landscape make forests more susceptible to fires through forest fragmentation, degradation, and fire spread from agricultural areas. Forested protected areas within the forest savanna mosaic experienced frequent fires, whereas the more humid forest areas located in the south and south-western portions of the study area had fewer fires as these rainforests tend to offer some buffering against fire encroachment. These results improve characterization of UGF fire regime and expand our understanding of the spatio-temporal dynamics of tropical forest fires in response to human and climatic pressures.

  12. Effects of the environment on fish juvenile growth in West African stressful estuaries

    NASA Astrophysics Data System (ADS)

    Diouf, K.; Guilhaumon, F.; Aliaume, C.; Ndiaye, P.; Chi, T. Do; Panfili, J.

    2009-06-01

    The knowledge of juvenile fish growth in extreme environmental conditions is a key to the understanding of adaptive responses and to the relevant management of natural populations. The juvenile growth of an extreme euryhaline tilapia species, Sarotherodon melanotheron (Cichlidae), was examined across a salinity gradient (20-118) in several West African estuarine ecosystems. Juveniles were collected during the reproduction period of two consecutive years (2003 and 2004) in six locations in the Saloum (Senegal) and Gambia estuaries. Age and growth were estimated using daily otolith microincrements. For each individual, otolith growth rates showed three different stages (slow, fast, decreasing): around 4 ± 0.5 μm d -1 during the first five days, 9 ± 0.5 μm d -1 during the next 15 days and 4 ± 0.50 μm d -1 at 60 days. Growth modelling and model comparisons were objectively made within an information theory framework using the multi-model inference from five growth models (linear, power, Gompertz, von Bertalanffy, and logistic). The combination of both the model adjustment inspection and the information theory model selection procedure allowed identification of the final set of models, including the less parameterised ones. The estimated growth rates were variable across spatial scales but not across temporal scales (except for one location), following exactly the salinity gradient with growth decrease towards the hypersaline conditions. The salinity gradient was closely related to all measured variables (condition factor, mean age, multi-model absolute growth rate) demonstrating the strong effect of hypersaline environmental conditions—induced by climate changes—on fish populations at an early stage.

  13. Skill, reproducibility and potential predictability of the West African monsoon in coupled GCMs

    NASA Astrophysics Data System (ADS)

    Philippon, N.; Doblas-Reyes, F. J.; Ruti, P. M.

    2010-07-01

    In the framework of the ENSEMBLES FP6 project, an ensemble prediction system based on five different state-of-the-art European coupled models has been developed. This study evaluates the performance of these models for forecasting the West African monsoon (WAM) at the monthly time scale. From simulations started the 1 May of each year and covering the period 1991-2001, the reproducibility and potential predictability (PP) of key parameters of the WAM—rainfall, zonal and meridional wind at four levels from the surface to 200 hPa, and specific humidity, from July to September—are assessed. The Sahelian rainfall mode of variability is not accurately reproduced contrary to the Guinean rainfall one: the correlation between observations (from CMAP) and the multi-model ensemble mean is 0.17 and 0.55, respectively. For the Sahelian mode, the correlation is consistent with a low PP of about ~6%. The PP of the Guinean mode is higher, ~44% suggesting a stronger forcing of the sea surface temperature on rainfall variability over this region. Parameters relative to the atmospheric dynamics are on average much more skillful and reproducible than rainfall. Among them, the first mode of variability of the zonal wind at 200 hPa that depicts the Tropical Easterly Jet, is correlated at 0.79 with its “observed” counterpart (from the NCEP/DOE2 reanalyses) and has a PP of 39%. Moreover, models reproduce the correlations between all the atmospheric dynamics parameters and the Sahelian rainfall in a satisfactory way. In that context, a statistical adaptation of the atmospheric dynamic forecasts, using a linear regression model with the leading principal components of the atmospheric dynamical parameters studied, leads to moderate receiver operating characteristic area under the curve and correlation skill scores for the Sahelian rainfall. These scores are however much higher than those obtained using the modelled rainfall.

  14. Mutual interaction between the West African Monsoon on the summer Mediterranean climate

    NASA Astrophysics Data System (ADS)

    Gaetani, M.; Baldi, M.; Dalu, G. A.

    2009-04-01

    Many studies have show that the West African Monsoon (WAM) is teleconnected with neighbouring regions, as the Mediterranean (Med) basin and the Tropical Atlantic, but also it is sensitive to the perturbations occurring even in remote regions, as the Indian sub-continent and the Tropical Pacific, these teleconnections being active on several time-scales, from intraseasonal to multidecadal. The WAM plays also an active role in the regional atmospheric circulation, inducing significant changes in rainfall, moisture, temperature, and wind distribution up to the North Africa. Within this framework, recent works were focused on the teleconnection between WAM and Med. WAM is strengthened by the north-easterly advection of moisture from the Med Sea, and, since the subsiding monsoonal air often invades the Med, there is a 2-way interaction between WAM and Med summer circulation. We study these interactions, applying SVD analysis to global NCEP Reanalysis and to rainfall data from CMAP, during the extended monsoonal season from May to October, on interannual and on intraseasonal time-scale. Dynamical features are explored using composite analysis, focusing on the role of this connection in the heat waves occurrence in the Med. We find that a strong WAM intensifies the Hadley meridional circulation, with a strengthening of the north Atlantic anticyclone and a weakening, even blocking, of the westerly flow in the Med. A deep inland penetration of WAM produces a northern shift of the Libyan anticyclone, with subsidence and high pressure affecting mainly the western Med. The positive feedback is due to the intensification of north-easterly flow from the eastern Med, which, reaching the Sahara desert, intensifies the intertropical front, favouring abundant monsoonal precipitation because of the added moist air.

  15. Changes in intraseasonal characteristics of temperature and rainfall and their impacts on West African crops

    NASA Astrophysics Data System (ADS)

    Biasutti, M.; Lobell, D. B.

    2012-12-01

    The CMIP3 and CMIP5 models project that, by the end of the century, the western Sahel will see much higher temperatures, a later beginning of the rainy season, and more rainfall accumulation. All of these changes can have a substantial impact on agricultural output, as higher temperatures and late onset are expected to lower yields, but wetter conditions could ameliorate, or even reverse, such changes. To better quantify the overall impact of the projected climate on yields as well as its uncertainty, we need to understand the sensitivity of yields to each climatic factor. This, in turn, is likely to depend on how the mean changes are realized. For example, the mean temperature increase might be less important than the increased occurrence of heat waves, and the mean rainfall increase less important than the increase in the number of rainy days. We therefore (i) validate the CMIP5 historical simulations on both their seasonal mean fields and their intraseasonal characteristics of temperature and rainfall (such as heat wave occurrence, monsoon onset dates, and dry spells); and (ii) characterize the mean changes predicted for the end of the century in terms of their expression at intraseasonal timescales. Whether a climatic driver affects the aggregated agricultural output of West African countries (as opposed to the yield of a single agricultural field) depends on the level of large scale coherence in its variations. We therefore quantify the degree of spatial coherence in the variability of intraseasonal characteristics in both observations (from station and gridded data) and models. Finally, we analyze variations in yields of staple crops (sorghum and millet) at the province and country level and relate them to variations in climate parameters (seasonal means and intraseasonal characteristics).

  16. Transversal analysis of public policies on user fees exemptions in six West African countries

    PubMed Central

    2012-01-01

    Background While more and more West African countries are implementing public user fees exemption policies, there is still little knowledge available on this topic. The long time required for scientific production, combined with the needs of decision-makers, led to the creation in 2010 of a project to support implementers in aggregating knowledge on their experiences. This article presents a transversal analysis of user fees exemption policies implemented in Benin, Burkina Faso, Mali, Niger, Togo and Senegal. Methods This was a multiple case study with several embedded levels of analysis. The cases were public user fees exemption policies selected by the participants because of their instructive value. The data used in the countries were taken from documentary analysis, interviews and questionnaires. The transversal analysis was based on a framework for studying five implementation components and five actors’ attitudes usually encountered in these policies. Results The analysis of the implementation components revealed: a majority of State financing; maintenance of centrally organized financing; a multiplicity of reimbursement methods; reimbursement delays and/or stock shortages; almost no implementation guides; a lack of support measures; communication plans that were rarely carried out, funded or renewed; health workers who were given general information but not details; poorly informed populations; almost no evaluation systems; ineffective and poorly funded coordination systems; low levels of community involvement; and incomplete referral-evacuation systems. With regard to actors’ attitudes, the analysis revealed: objectives that were appreciated by everyone; dissatisfaction with the implementation; specific tensions between healthcare providers and patients; overall satisfaction among patients, but still some problems; the perception that while the financial barrier has been removed, other barriers persist; occasionally a reorganization of practices

  17. Ultrastructural observations on the terminal segment epithelium of the seminiferous tubule of West African dwarf goats.

    PubMed Central

    Ezeasor, D N

    1986-01-01

    In the testes of West African dwarf goats, modified Sertoli cells comprise the major component of the terminal segment epithelium. They resemble Sertoli cells proper but differ in the paucity of agranular endoplasmic reticulum and lipid droplets. Cell attachment devices present include rudimentary desmosomes and occasional multiple contacts of opposing plasma membranes, interrupted by segments of slightly expanded intercellular space. A few generative cells are present in the proximal zone of the epithelium, but their development appears to terminate as early spermatids which hang loosely on the luminal surface. The middle zone epithelium comprises vacuolated cells lying among other cells containing abundant microtubules in their subapical cytoplasm. Globular expansions of the intercellular space are also apparent. The terminal plug contains two cell types. Type I are inclined, columnar cells which contain profuse arrays of agranular endoplasmic reticulum in their apical cytoplasm. Type II are smaller cells located at the apex of the plug. Each possesses cytoplasmic processes, which surround the apices of Type I cells. The modified Sertoli cells of all zones and the Type II plug cells contain remnants of spermatozoa at different stages of degradation. The general absence of developing generative cells in the terminal segment epithelium may be related to the paucity of agranular endoplasmic reticulum in the basal cytoplasm of modified Sertoli cells and the absence of typical Sertoli-Sertoli junctional specialisations. Structural modifications evident in the middle and distal zones facilitate distalward movement of materials, while the attenuation and modification of the lumen distally may facilitate phagocytosis of abnormal spermatozoa. Images Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 5 Fig. 6 Fig. 7 Fig. 8 Fig. 9 Fig. 10 Fig. 11 Fig. 12 PMID:3693043

  18. Phylogeography of the Afromontane Prunus africana reveals a former migration corridor between East and West African highlands.

    PubMed

    Kadu, C A C; Schueler, S; Konrad, H; Muluvi, G M M; Eyog-Matig, O; Muchugi, A; Williams, V L; Ramamonjisoa, L; Kapinga, C; Foahom, B; Katsvanga, C; Hafashimana, D; Obama, C; Geburek, T

    2011-01-01

    Scattered populations of the same tree species in montane forests through Africa have led to speculations on the origins of distributions. Here, we inferred the colonization history of the Afromontane tree Prunus africana using seven chloroplast DNA loci to study 582 individuals from 32 populations sampled in a range-wide survey from across Africa, revealing 22 haplotypes. The predominant haplotype, HT1a, occurred in 13 populations of eastern and southern Africa, while a second common haplotype, HT1m, occurred in populations of western Uganda and western Africa. The high differentiation observed between populations in East Africa was unexpected, with stands in western Uganda belonging with the western African lineage. High genetic differentiation among populations revealed using ordered alleles (N(ST) = 0.840) compared with unordered alleles (G(ST) = 0.735), indicated a clear phylogeographic pattern. Bayesian coalescence modelling suggested that 'east' and 'west' African types likely split early during southward migration of the species, while further more recent splitting events occurred among populations in the East of the continent. The high genetic similarity found between western Uganda and west African populations indicates that a former Afromontane migration corridor may have existed through Equatorial Africa.

  19. Has the middle-level anaesthesia manpower training program of the West African College of Surgeons fulfilled its objectives?

    PubMed

    Bode, C O; Olatosi, J; Amposah, G; Desalu, I

    2013-05-01

    An audit of the West African College of Surgeons' middle-level Diploma in Anaesthesia program was carried out to determine the current status of the diplomates. Using the West African College of Surgeons' database, social media and personal communications, the current status of Diploma in Anaesthesia graduates spanning 20 years was determined. A total of 303 (97%) out of 311 of graduates were traced. Eighty percent were still practising anaesthesia, while 5% were now in other disciplines. Two hundred and four (67.3%) still resided in West Africa (183 in Nigeria, 50 in Ghana, one in Sierra Leone), while 69 (22.7%) were abroad: 35 (11.5%) in the United Kingdom, 21 (6.9%) in the United States of America and four (1.3%) in Canada. More Ghanaian than Nigerian graduates had emigrated (41 vs 14%, respectively). Only 9% of diplomates remained in rural communities (as originally envisaged), while 31% were now consultants (as fellows) and 30% were registrars in fellowship training. These findings indicate that most diplomates moved on to acquire further qualifications and a significant proportion migrated. The program did not appear to have achieved the objectives of meeting rural middle-level manpower needs in anaesthesia as envisaged. It has, however, boosted the recruitment drive for residency training in anaesthesia. Perhaps a less migrant cadre such as nurses may better serve this function if recruited into a suitably designed training program in countries desiring to use middle-level manpower in anaesthesia.

  20. WASCAL - West African Science Service Center on Climate Change and Adapted Land Use Regional Climate Simulations and Land-Atmosphere Simulations for West Africa at DKRZ and elsewhere

    NASA Astrophysics Data System (ADS)

    Hamann, Ilse; Arnault, Joel; Bliefernicht, Jan; Klein, Cornelia; Heinzeller, Dominikus; Kunstmann, Harald

    2014-05-01

    Changing climate and hydro-meteorological boundary conditions are among the most severe challenges to Africa in the 21st century. In particular West Africa faces an urgent need to develop effective adaptation and mitigation strategies to cope with negative impacts on humans and environment due to climate change, increased hydro-meteorological variability and land use changes. To help meet these challenges, the German Federal Ministry of Education and Research (BMBF) started an initiative with institutions in Germany and West African countries to establish together a West African Science Service Center on Climate Change and Adapted Land Use (WASCAL). This activity is accompanied by an establishment of trans-boundary observation networks, an interdisciplinary core research program and graduate research programs on climate change and related issues for strengthening the analytical capabilities of the Science Service Center. A key research activity of the WASCAL Competence Center is the provision of regional climate simulations in a fine spatio-temporal resolution for the core research sites of WASCAL for the present and the near future. The climate information is needed for subsequent local climate impact studies in agriculture, water resources and further socio-economic sectors. The simulation experiments are performed using regional climate models such as COSMO-CLM, RegCM and WRF and statistical techniques for a further refinement of the projections. The core research sites of WASCAL are located in the Sudanian Savannah belt in Northern Ghana, Southern Burkina Faso and Northern Benin. The climate in this region is semi-arid with six rainy months. Due to the strong population growth in West Africa, many areas of the Sudanian Savannah have been already converted to farmland since the majority of the people are living directly or indirectly from the income produced in agriculture. The simulation experiments of the Competence Center and the Core Research Program are

  1. The West African monsoon: Contribution of the AMMA multidisciplinary programme to the study of a regional climate system.

    NASA Astrophysics Data System (ADS)

    Lebel, T.; Janicot, S.; Redelsperger, J. L.; Parker, D. J.; Thorncroft, C. D.

    2015-12-01

    The AMMA international project aims at improving our knowledge and understanding of the West African monsoon and its variability with an emphasis on daily-to-interannual timescales. AMMA is motivated by an interest in fundamental scientific issues and by the societal need for improved prediction of the WAM and its impacts on water resources, health and food security for West African nations. The West African monsoon (WAM) has a distinctive annual cycle in rainfall that remains a challenge to understand and predict. The location of peak rainfall, which resides in the Northern Hemisphere throughout the year, moves from the ocean to the land in boreal spring. Around the end of June there is a rapid shift in the location of peak rainfall between the coast and around 10°N where it remains until about the end of August. In September the peak rainfall returns equatorward at a relatively steady pace and is located over the ocean again by November. The fact that the peak rainfall migrates irregularly compared to the peak solar heating is due to the interactions that occur between the land, the atmosphere and the ocean. To gain a better understanding of this complex climate system, a large international research programme was launched in 2002, the biggest of its kind into environment and climate ever attempted in Africa. AMMA has involved a comprehensive field experiment bringing together ocean, land and atmospheric measurements, on timescales ranging from hourly and daily variability up to the changes in seasonal activity over a number of years. This presentation will focus on the description of the field programme and its accomplishments, and address some key questions that have been recently identified to form the core of AMMA-Phase 2.

  2. The West African monsoon: Contribution of the AMMA multidisciplinary programme to the study of a regional climate system.

    NASA Astrophysics Data System (ADS)

    Lebel, T.; Janicot, S.; Redelsperger, J. L.; Parker, D. J.; Thorncroft, C. D.

    2014-12-01

    The AMMA international project aims at improving our knowledge and understanding of the West African monsoon and its variability with an emphasis on daily-to-interannual timescales. AMMA is motivated by an interest in fundamental scientific issues and by the societal need for improved prediction of the WAM and its impacts on water resources, health and food security for West African nations. The West African monsoon (WAM) has a distinctive annual cycle in rainfall that remains a challenge to understand and predict. The location of peak rainfall, which resides in the Northern Hemisphere throughout the year, moves from the ocean to the land in boreal spring. Around the end of June there is a rapid shift in the location of peak rainfall between the coast and around 10°N where it remains until about the end of August. In September the peak rainfall returns equatorward at a relatively steady pace and is located over the ocean again by November. The fact that the peak rainfall migrates irregularly compared to the peak solar heating is due to the interactions that occur between the land, the atmosphere and the ocean. To gain a better understanding of this complex climate system, a large international research programme was launched in 2002, the biggest of its kind into environment and climate ever attempted in Africa. AMMA has involved a comprehensive field experiment bringing together ocean, land and atmospheric measurements, on timescales ranging from hourly and daily variability up to the changes in seasonal activity over a number of years. This presentation will focus on the description of the field programme and its accomplishments, and address some key questions that have been recently identified to form the core of AMMA-Phase 2.

  3. Differential opening of the Central and South Atlantic Oceans and the opening of the West African rift system

    NASA Astrophysics Data System (ADS)

    Fairhead, J. D.; Binks, R. M.

    1991-02-01

    Plate tectonic studies of the development of the Central and South Atlantic Oceans using Seasat and Geosat altimeter and magnetic anomaly isochron data now provide quantitative models of seafloor spreading through time. Such models enable an initial assessment of the differential opening between these two oceanic basins to be determined. The Equatorial Atlantic is an integral part of this oceanic rifting process, allowing stresses arising from the differential opening to be dissipated into both the Caribbean and Africa along its northern and southern boundaries respectively. The tectonic model for the West African rift system, based on geological and geophysical studies, shows a series of strike-slip fault zones diverging into Africa from the Gulf of Guinea and dissipating their shear movement into the development of extensional basins orientated perpendicular to these faults zones. The development of the West African rift system was contemporaneous with the early opening of the South Atlantic, continued to develop well after the final breakup of South America from Africa and did not cease until the late Cretaceous when there was a major phase of basin inversion and deformation. Santonian ( ~ 80 Ma) deformation across the Benue Trough (Nigeria) is broadly contemporaneous with dextral shear reactivation of the central African fracture system which, in turn resulted in renewed extension in the Sudan basins during the late Cretaceous and early Tertiary. This paper illustrates the close linkage in both time and space between the history of the African rift basins and the opening of the Atlantic. Both exhibit distinct phases of evolution with the rift basins developing in direct response to the differential opening between the Central and South Atlantic in order to dissipate stresses generated by this opening. The Mesozoic tectonic model proposed is therefore one of an intimate interaction between oceanic and continental tectonics.

  4. Haemonchotolerance in West African Dwarf goats: contribution to sustainable, anthelmintics-free helminth control in traditionally managed Nigerian dwarf goats

    PubMed Central

    Chiejina, Samuel N.; Behnke, Jerzy M.; Fakae, Barineme B.

    2015-01-01

    West African Dwarf (WAD) goats are extremely important in the rural village economy of West Africa, but still little is known about their biology, ecology and capacity to cope with gastrointestinal nematode (GIN) infections. Here, we summarise the history of this breed and explain its economic importance in rural West Africa. We review recent work showing that Nigerian WAD goats are highly trypanotolerant and resist infections with Haemonchus contortus more effectively than other breeds of domestic goat (haemonchotolerance). We believe that haemonchotolerance is largely responsible for the generally low level GIN infections and absence of clinical haemonchosis in WADs under field conditions, and has contributed to the relatively successful and sustainable, anthelmintics-free, small-scale system of goat husbandry in Nigeria’s humid zone, and is immunologically based and genetically controlled. If haemonchotolerance can be shown to be genetically controlled, it should be possible to exploit the underlying genes to improve GIN resistance among productive fibre and milk producing breeds of goats, most of which are highly susceptible to nematode infections. Genetic resistance to GIN and trypanosome infections would obviate the need for expensive chemotherapy, mostly unaffordable to small-holder farmers in Africa, and a significant cost of goat husbandry in more developed countries. Either introgression of resistance alleles into susceptible breeds by conventional breeding, or transgenesis could be used to develop novel parasite-resistant, but highly productive breeds, or to improve the resistance of existing breeds, benefitting the local West African rural economy as well as global caprine livestock agriculture. PMID:25744655

  5. Stratospheric variability of wave activity and parameters in equatorial coastal and tropical sites during the West African monsoon

    NASA Astrophysics Data System (ADS)

    Kafando, P.; Chane-Ming, F.; Petitdidier, M.

    2015-08-01

    Recent numerical studies in stratospheric dynamics and its variability as well as climate, have highlighted the need of more observational analyses to improve simulation of the West African monsoon (WAM). In this paper, activity and spectral characteristics of short-scale vertical waves (wavelengths <4 km) are analysed in equatorial coastal and tropical lower stratosphere during the WAM. A first detailed description of such waves over West Africa is derived from high-resolution vertical profiles of temperature and horizontal wind obtained during Intensive Observation Period of the African Monsoon Multidisciplinary Analyses (AMMA) Campaign 2006. Monthly variation of wave energy density is revealed to trace the progression of the inter-tropical convergence zone (ITCZ) over West Africa. Mesoscale inertia gravity-waves structures with vertical and horizontal wavelengths of 1.5-2.5 and 400-1100 km respectively and intrinsic frequencies of 1.1-2.2 f or periods <2 days are observed in the tropical LS with intense activity during July and August when the WAM is installed over the tropical West Africa. Over equatorial region, gravity waves with intrinsic frequencies of 1.4-4 f or periods <5.2 days, vertical wavelength of 2.1 km and long horizontal wavelengths of 1300 km are intense during the WAM coastal phase. From July to October, gravity waves with intrinsic frequencies of 1.2-3.8 f or periods <6 days, vertical wavelength of 2.1 km and horizontal wavelengths of 1650 km are less intense during the WAM Sahelian phase of the WAM, March-June. Unlike potential energy density, kinetic energy density is observed to be a good proxy for the activity of short-scale vertical waves during the WAM because quasi-inertial waves are dominant. Long-term wave activity variation from January 2001 to December 2009, highlights strong year-to-year variation superimposed on convective activity and quasi-biennial oscillation-like variations especially above tropical stations.

  6. Revisiting the role of global SST anomalies and their effects on West African monsoon variability

    NASA Astrophysics Data System (ADS)

    Pomposi, Catherine; Kushnir, Yochanan; Giannini, Alessandra

    2016-04-01

    The West African Monsoon is a significant component of the global monsoon system, delivering the majority of annual precipitation for the Sahel and varying on timescales from seasons to decades and beyond. Much of the internal variability of this system is driven by sea surface temperature (SST) anomalies and their resulting atmospheric teleconnections linking oceanic changes to land-based precipitation. Previous idealized studies have identified the role of particular ocean basins in driving monsoon variations on a number of key timescales, including the Atlantic basin as the main driver behind decadal-scale changes and the Pacific basin for interannual variability. However, understanding of how the monsoon responds to global SSTs remains incomplete because the system can be affected by moisture availability locally as well as tropical atmospheric stability, both of which are influenced by ocean temperatures. Furthermore, the complexity of how the global ocean basins change in relation to one another (what we refer to as superposition of anomalies) can result in Sahel precipitation anomalies that are contrary to what one might posit when considering the state of a single basin alone (e.g. the 2015 El Niño event and a relatively wet Sahel). The aim of this work is to revisit the role of global SSTs in driving Sahel rainfall variability over the recent past using a blending of observations and new model output. We seek to disentangle the state of various basins in combination with each other in driving normal or anomalously dry or wet years, resolving the ways that remote and local ocean forcings affect the movement of convection from the Guinea coast inland and northward into the Sahel, and include the study of circulation and stability components of the atmosphere. Preliminary diagnostic work suggests that varying SST conditions across ocean basins could imprint distinctly different precipitation responses in the Sahel. For example, precipitation anomalies are

  7. Identification, tissue distribution and functional characterization of the ghrelin receptor in West African lungfish, Protopterus annectens.

    PubMed

    Kaiya, Hiroyuki; Konno, Norifumi; Kangawa, Kenji; Uchiyama, Minoru; Miyazato, Mikiya

    2014-12-01

    We identified two ghrelin receptor isoforms, the ghrelin receptor type-1a (GHS-R1a) and its alternative splice form (GHS-R1b) for West African lungfish, Protopterus annectens. Lungfish GHS-R1a and 1b comprised 361 and 281 amino acids, respectively. Lungfish GHS-R1a showed the highest identity to coelacanth GHS-R1a (80.4%). The highest expression of GHS-R1a mRNAs was seen in the brain, liver, ovary, heart, intestine, and gills. GHS-R1b mRNAs were also detected in the same tissues with GHS-R1a, but their expression level was 1/20 that of GHS-R1a. In human embryonic kidney 293 cells transiently expressing lungfish GHS-R1a, rat and bullfrog ghrelin, and two GHS-R1a agonists, GHRP-6 and hexarelin, increased intracellular Ca(2+) concentrations. The intensity of the Ca(2+) increases induced by GHS-R1a agonists was twice when compared to that induced by ghrelin, although the median effective doses (ED50) were similar, suggesting a long-lasting effect of GHS-R1a agonists with similar affinity. We also examined changes in the GHS-R gene expression during an eight-week estivation. Body weight was slightly lowered, but plasma sodium and glucose concentrations decreased; plasma urea concentration increased significantly 4weeks after the start of estivation. Overall, expression of GHS-R1a mRNA decreased, but changes in GHS-R1b mRNA expression were inconsistent with those of GHS-R1a during estivation, suggesting an involvement of GHS-R in energy homeostasis, as seen in mammals. Our results suggest that the ghrelin-GHS-R1a system is present in this lungfish although ghrelin has not yet been found. The structure of GHS-R1a is closer to that of tetrapods than Actinopterygian fish, indicating a process of evolution that follows the Crossopterygii such as coelacanth.

  8. Glomus africanum and G. iranicum, two new species of arbuscular mycorrhizal fungi (Glomeromycota).

    PubMed

    Błaszkowski, Janusz; Kovács, Gábor M; Balázs, Tímea K; Orlowska, Elzbieta; Sadravi, Mehdi; Wubet, Tesfaye; Buscot, François

    2010-01-01

    Two new arbuscular mycorrhizal fungal species (Glomeromycota) of genus Glomus, G. africanum and G. iranicum, are described and illustrated. Both species formed spores in loose clusters and singly in soil and G. iranicum sometimes inside roots. G. africanum spores are pale yellow to brownish yellow, globose to subglobose, (60-)87(-125) μm diam, sometimes ovoid to irregular, 80-110 x 90-140 μm. The spore wall consists of a semipermanent, hyaline, outer layer and a laminate, smooth, pale yellow to brownish yellow, inner layer, which always is markedly thinner than the outer layer. G. iranicum spores are hyaline to pastel yellow, globose to subglobose, (13-)40(-56) μm diam, rarely egg-shaped, prolate to irregular, 39-54 x 48-65 μm. The spore wall consists of three smooth layers: one mucilaginous, short-lived, hyaline, outermost; one permanent, semirigid, hyaline, middle; and one laminate, hyaline to pastel yellow, innermost. Only the outermost spore wall layer of G. iranicum stains red in Melzer's reagent. In the field G. africanum was associated with roots of five plant species and an unrecognized shrub colonizing maritime sand dunes of two countries in Europe and two in Africa, and G. iranicum was associated with Triticum aestivum cultivated in southwestern Iran. In one-species cultures with Plantago lanceolata as the host plant G. africanum and G. iranicum formed arbuscular mycorrhizae. Phylogenetic analyses of partial SSU sequences of nrDNA placed the two new species in Glomus group A. Both species were distinctly separated from sequences of described Glomus species.

  9. Glomus africanum and G. iranicum, two new species of arbuscular mycorrhizal fungi (Glomeromycota).

    PubMed

    Błaszkowski, Janusz; Kovács, Gábor M; Balázs, Tímea K; Orlowska, Elzbieta; Sadravi, Mehdi; Wubet, Tesfaye; Buscot, François

    2010-01-01

    Two new arbuscular mycorrhizal fungal species (Glomeromycota) of genus Glomus, G. africanum and G. iranicum, are described and illustrated. Both species formed spores in loose clusters and singly in soil and G. iranicum sometimes inside roots. G. africanum spores are pale yellow to brownish yellow, globose to subglobose, (60-)87(-125) μm diam, sometimes ovoid to irregular, 80-110 x 90-140 μm. The spore wall consists of a semipermanent, hyaline, outer layer and a laminate, smooth, pale yellow to brownish yellow, inner layer, which always is markedly thinner than the outer layer. G. iranicum spores are hyaline to pastel yellow, globose to subglobose, (13-)40(-56) μm diam, rarely egg-shaped, prolate to irregular, 39-54 x 48-65 μm. The spore wall consists of three smooth layers: one mucilaginous, short-lived, hyaline, outermost; one permanent, semirigid, hyaline, middle; and one laminate, hyaline to pastel yellow, innermost. Only the outermost spore wall layer of G. iranicum stains red in Melzer's reagent. In the field G. africanum was associated with roots of five plant species and an unrecognized shrub colonizing maritime sand dunes of two countries in Europe and two in Africa, and G. iranicum was associated with Triticum aestivum cultivated in southwestern Iran. In one-species cultures with Plantago lanceolata as the host plant G. africanum and G. iranicum formed arbuscular mycorrhizae. Phylogenetic analyses of partial SSU sequences of nrDNA placed the two new species in Glomus group A. Both species were distinctly separated from sequences of described Glomus species. PMID:20943558

  10. Small reservoirs in the West African savanna: Usage, monitoring and impact (Invited)

    NASA Astrophysics Data System (ADS)

    Van De Giesen, N.; Liebe, J. R.; Annor, F.; Andreini, M.

    2013-12-01

    The West African savanna is dotted with thousands of small reservoirs. These reservoirs were primarily built for irrigation purposes, supplying supplementary irrigation in the rainy season and full irrigation in the dry season. Some reservoirs were specifically constructed for watering cattle. Most reservoirs, however, now fulfill a multitude of functions in addition to irrigation and cattle watering, such as fishing, bathing, household water, supply of construction materials, and recreation. In the framework of the Small Reservoirs Project (www.smallreservoirs.org), extensive research has been undertaken over the past ten years that addresses the functioning of these reservoirs and the development of new monitoring methods. This presentation will give a general overview of our findings with respect to history, usage, and hydrological impact of small reservoirs in West Africa. In general, no comprehensive databases are available to local and national governments that contain all reservoirs and their attributes. Remote sensing, therefore, offers an interesting alternative to produce inventories of small reservoirs in a cost effective way. The most straightforward application is the mapping of small reservoirs with the aid of optical satellite images. Open water tends to stand out clearly from its surroundings in such images, allowing for relatively accurate determination of the location and surface area of the reservoirs. An important early discovery was that within a given geomorphological region, there is a very good correlation between surface area and storage volume. Once this correlation is established through a small sub-sample of the reservoirs, all volumes can be calculated on the basis of surfaces as determined through remote sensing. In turn, this opens up the opportunity to monitor water storage over the year by means of satellite images. Optical images are usually not available during large parts of the year due to cloud cover. This holds especially true

  11. Analysis and Prediction of West African Moist Events during the Boreal Spring of 2009

    NASA Astrophysics Data System (ADS)

    Mera, Roberto Javier

    Weather and climate in Sahelian West Africa are dominated by two major wind systems, the southwesterly West African Monsoon (WAM) and the northeasterly (Harmattan) trade winds. In addition to the agricultural benefit of the WAM, the public health sector is affected given the relationship between the onset of moisture and end of meningitis outbreaks. Knowledge and prediction of moisture distribution during the boreal spring is vital to the mitigation of meningitis by providing guidance for vaccine dissemination. The goal of the present study is to (a) develop a climatology and conceptual model of the moisture regime during the boreal spring, (b) investigate the role of extra-tropical and Convectively-coupled Equatorial Waves (CCEWs) on the modulation of westward moving synoptic waves and (c) determine the efficacy of a regional model as a tool for predicting moisture variability. Medical reports during 2009, along with continuous meteorological observations at Kano, Nigeria, showed that the advent of high humidity correlated with cessation of the disease. Further analysis of the 2009 boreal spring elucidated the presence of short-term moist events that modulated surface moisture on temporal scales relevant to the health sector. The May moist event (MME) provided insight into interplays among climate anomalies, extra-tropical systems, equatorially trapped waves and westward-propagating synoptic disturbances. The synoptic disturbance initiated 7 May and traveled westward to the coast by 12 May. There was a marked, semi-stationary moist anomaly in the precipitable water field (kg m-2) east of 10°E through late April and early May, that moved westward at the time of the MME. Further inspection revealed a mid-latitude system may have played a role in increasing the latitudinal amplitude of the MME. CCEWs were also found to have an impact on the MME. A coherent Kelvin wave propagated through the region, providing increased monsoonal flow and heightened convection. A

  12. Geochronology of the Birim Supergroup of the West African craton in the Wa-Bolé region of west-central Ghana: Implications for the stratigraphic framework

    NASA Astrophysics Data System (ADS)

    de Kock, G. S.; Armstrong, R. A.; Siegfried, H. P.; Thomas, E.

    2011-01-01

    The Birim rocks of the West African craton comprise belts of greenschist- to amphibolite-grade gneiss and schist, and subparallel basins of greenschist-grade phyllite of volcaniclastic and epiclastic origin, which were intruded by igneous rocks. The granitoids intruded between 2213 and 2060 Ma and overlap with the volcaniclastic units dated between 2211 and 2064 Ma. The simultaneous occurrence of the magmatic events and irregular distribution of the rock ages hamper the formulation of a stratigraphic succession. SHRIMP spot analyses were done on older cores, crystals and rims from 23 rocks from the Bolé-Wa region in west-central Ghana. The crystallization ages range from 2195 to 2118 Ma, the inherited ages from 2876 to 2130 Ma, and metamorphic ages from 2114 to 2090 Ma. Aided by metamorphic, structural and chemical studies an older geotectonic cycle (2195-2150 Ma), containing the Dole and Guropie Suite and Bolé Group, was established. These units were subjected to several orthogonal and shear deformation events. These events were followed by the contemporaneous Sawla calc-alkaline monzonitic plutonism (2132-2126 Ma) and deposition of the epiclastic Maluwe Group (2137-2125 Ma) of calc-alkaline felsic to tholeiitic volcanic origin. Deformation of the basin beds was succeeded by the intrusion of the Tanina Suite granitoids of 2122-2120 Ma, which, themselves, were deformed prior to 2119 Ma. At 2118 Ma syenite and gabbro intruded along conjugate extension fractures. The gabbro and syenite of the Wakawaka Suite were only affected by three events of brittle strike-slip faulting. The first had significant displacement along NNE- to NE-directed shear zones, while the latter only formed conjugate joint systems with limited transport. Palaeo- to Neoarchaean cores, the oldest yet reported in the Baoulé Mossi domain, are restricted to the gneissic Dole Suite biotite granites. The presence of Dole-, Guropie-, Sawla-, and Tanina-aged older cores and grains in younger rocks

  13. Importance of mitochondrial haplotypes and maternal lineage in sprint performance among individuals of West African ancestry.

    PubMed

    Deason, M; Scott, R; Irwin, L; Macaulay, V; Fuku, N; Tanaka, M; Irving, R; Charlton, V; Morrison, E; Austin, K; Pitsiladis, Y P

    2012-04-01

    Mitochondrial DNA (mtDNA) is inherited solely along the matriline, giving insight into both ancestry and prehistory. Individuals of sub-Saharan ancestry are overrepresented in sprint athletics, suggesting a genetic advantage. The purpose of this study was to compare the mtDNA haplogroup data of elite groups of Jamaican and African-American sprinters against respective controls to assess any differences in maternal lineage. The first hypervariable region of mtDNA was haplogrouped in elite Jamaican athletes (N=107) and Jamaican controls (N=293), and elite African-American athletes (N=119) and African-American controls (N=1148). Exact tests of total population differentiation were performed on total haplogroup frequencies. The frequency of non-sub-Saharan haplogroups in Jamaican athletes and Jamaican controls was similar (1.87% and 1.71%, respectively) and lower than that of African-American athletes and African-American controls (21.01% and 8.19%, respectively). There was no significant difference in total haplogroup frequencies between Jamaican athletes and Jamaican controls (P=0.551 ± 0.005); however, there was a highly significant difference between African-American athletes and African-American controls (P<0.001). The finding of statistically similar mtDNA haplogroup distributions in Jamaican athletes and Jamaican controls suggests that elite Jamaican sprinters are derived from the same source population and there is neither population stratification nor isolation for sprint performance. The significant difference between African-American sprinters and African-American controls suggests that the maternal admixture may play a role in sprint performance.

  14. Impact of GCM boundary forcing on regional climate modeling of West African summer monsoon precipitation and circulation features

    NASA Astrophysics Data System (ADS)

    Kebe, Ibourahima; Sylla, Mouhamadou Bamba; Omotosho, Jerome Adebayo; Nikiema, Pinghouinde Michel; Gibba, Peter; Giorgi, Filippo

    2016-05-01

    In this study, the latest version of the International Centre for Theoretical Physics Regional Climate Model (RegCM4) driven by three CMIP5 Global Climate Models (GCMs) is used at 25 km grid spacing over West Africa to investigate the impact of lateral boundary forcings on the simulation of monsoon precipitation and its relationship with regional circulation features. We find that the RegCM4 experiments along with their multimodel ensemble generally reproduce the location of the main precipitation characteristics over the region and improve upon the corresponding driving GCMs. However, the provision of different forcing boundary conditions leads to substantially different precipitation magnitudes and spatial patterns. For instance, while RegCM4 nested within GFDL-ESM-2M and HadGEM2-ES exhibits some underestimations of precipitation and an excessively narrow Intertropical Convergence Zone, the MPI-ESM-MR driven run produces precipitation spatial distribution and magnitudes more similar to observations. Such a superior performance originates from a much better simulation of the interactions between baroclinicity, temperature gradient and African Easterly Jet along with an improved connection between the Isentropic Potential Vorticity, its gradient and the African Easterly Waves dynamics. We conclude that a good performing GCM in terms of monsoon dynamical features (in this case MPI-ESM-MR) is needed to drive RCMs in order to achieve a better representation of the West Africa summer monsoon precipitation.

  15. Comparative study of potential transfer of natural and anthropogenic cadmium to plankton communities in the North-West African upwelling.

    PubMed

    Auger, P A; Machu, E; Gorgues, T; Grima, N; Waeles, M

    2015-02-01

    A Lagrangian approach based on a physical-biogeochemical modeling was used to compare the potential transfer of cadmium (Cd) from natural and anthropogenic sources to plankton communities (Cd-uptake) in the North-West African upwelling. In this region, coastal upwelling was estimated to be the main natural source of Cd while the most significant anthropogenic source for marine ecosystem is provided by phosphate industry. In our model experiment, Cd-uptake (natural or anthropogenic) in the North-West African upwelling is the result of an interplay between the Cd dispersion (by advection processes) and the simulated biological productivity. In the Moroccan waters, advection processes limit the residence time of water masses resulting in a low natural Cd-uptake by plankton communities while anthropogenic Cd-uptake is high. As expected, the situation is reversed in the Senegalo-Mauritanian upwelling where natural Cd-uptake is higher than anthropogenic Cd-uptake. Based upon an estimate of Cd sources, our modeling study shows, unexpectedly, that the anthropogenic signal of potential Cd-bioaccumulation in the Moroccan upwelling is of the same order of magnitude as the natural signal mainly present in the Senegalo-Mauritanian upwelling region. A comparison with observed Cd levels in mollusk and fishes, which shows overall agreement with our simulations, is confirming our estimates.

  16. HLA-DRB1 and -DQB1 loci in three west African ethnic groups: genetic relationship with sub-Saharan African and European populations.

    PubMed

    Lulli, Patrizia; Mangano, Valentina D; Onori, Annamaria; Batini, Chiara; Luoni, Gaia; Sirima, Bienvenu S; Nebie, Issa; Chessa, Luciana; Petrarca, Vincenzo; Modiano, David

    2009-11-01

    The Fulani of west Africa have been shown to be less susceptible to malaria and to mount a stronger immune response to malaria than sympatric ethnic groups. The analysis of HLA diversity is useful for the assessment of the genetic distance between the Fulani and sympatric populations, which represents the necessary theoretical background for the investigation of genetic determinants of susceptibility to malaria. We assessed the polymorphism of HLA-DRB1 and -DQB1 loci and analyzed the distribution of alleles/haplotypes in Fulani, Mossi, and Rimaibé from Burkina Faso. We then investigated the genetic relationship of these three ethnic groups with other sub-Saharan African populations as well as with Europeans. We confirmed that the Fulani from Burkina Faso are genetically distinct from sympatric Mossi and Rimaibé. Furthermore the Fulani from Burkina Faso are close to those from The Gambia and, intriguingly, share the distribution of specific alleles with east African populations (Amhara and Oromo). It is noteworthy that the HLA-DRB1*04 and -DQB1*02 alleles, which are implicated in the development of several autoimmune diseases, are present at high frequency in the Fulani, suggesting their potential involvement in the enhanced immune reactivity observed in this population.

  17. Interannual vs decadal SST forced responses of the West African monsoon

    NASA Astrophysics Data System (ADS)

    Rodríguez-Fonseca, Belen

    2010-05-01

    One of the strongest interdecadal signals on the planet has been observed in the Sahelian rainfall during the second half of the XXth century, from wet conditions in the 50's and 60's to drier conditions after the 70's. Parallel to this, several decadal signals have experienced a change from the 70's, and also the influence of the global warming has increased from this decade. From a global perspective the West African rainfall variability is highly modulated by SST forced signals. Many works have pointed out to the Atlantic and Pacific equatorial modes influence on interannual timescales; and to the AMO and the Pacific and Indian Ocean at multidecadal timescales. In the AMMA-EU context the modulation of the interannual modes by the decadal variability together with the influence of the GW has been studied by analysing the interannual modes of variability before and after the 70's. The results indicate the presence of different interannual telecconections between these two periods and, hence, of different anomalous rainfall responses. The importance of the background state modulated by multidecadal variability in the interannual modes is stated in this work. Also, an interesting discussion appears if we wonder whether or not the background state is affected, in turn, by anthropogenic climate change. Recent observational and GCM studies have shown, following the results of Polo et al. (2008), how the Atlantic and Pacific Niños present a dynamical link during the last decades of the XX century (Rodriguez-Fonseca et al., 2009). In this way, the positive (negative) phase of the summer Pacific Niño signal has been found to be connected with a negative (positive) phase of the Equatorial Atlantic mode (EM or Atlantic Niño, Polo et al., 2008); a pattern which leads the summer Atlantic variability. The determinant impact of this connection on the WA monsoon has been addressed by defining a global summer tropical mode accounting for more than the 60% of the rainfall

  18. The relationship between African easterly waves and daily rainfall over West Africa: observations and regional climate simulations

    NASA Astrophysics Data System (ADS)

    Crétat, Julien; Vizy, Edward K.; Cook, Kerry H.

    2015-01-01

    The relationship between summer African easterly waves (AEWs) and daily rainfall is assessed in West Africa for 1998-2008 using various reanalyses, satellite-derived rainfall products, and a regional climate model (RCM) run at 90- and 30-km resolutions. 3-5 and 6-9 day AEWs are extracted by filtering daily 700 hPa meridional wind time series at 1°W and 11.5°N, and 1°W and 17.5°N, respectively. Both observed and simulated rainfall anomalies are of larger magnitude over West Africa during 3-5-d than 6-9-d AEWs. The RCM simulates larger rainfall rates in phase with the 3-5-d wave trough instead of ahead, unlike the observations, and overestimates the intensity and spatial coverage of rainfall associated with 6-9-d AEWs. The observed and simulated co-variability between 3-5-d (6-9-d) AEW activity and daily rainfall is strong (weak) and mostly located south (north) of 15°N. However, the RCM overestimates the spatial coverage of the AEW-rainfall relationship in the longitudinal (latitudinal) direction in the case of 3-5-d (6-9-d) AEWs. Observed and simulated daily intense rainfall events, extracted using a percentile threshold approach, are mostly located south of 15°N during summer. The observed relationship between their frequency of occurrence and active 3-5-d AEWs is maximal west of 8°E, while extends up to southern Chad in both RCM simulations. Their magnitude is also largely overestimated by the RCM, indicating an exaggerated coupling between the wave activity and the convection. Finally, observed and simulated 3-5-d AEWs establish the most favorable synoptic conditions for the development of intense rainfall events over West Africa.

  19. Cloning of a prothrombin activator-like metalloproteinase from the West African saw-scaled viper, Echis ocellatus.

    PubMed

    Hasson, S S; Theakston, R D G; Harrison, R A

    2003-11-01

    Systemic envenoming by the saw-scaled viper, Echis ocellatus, is responsible for more deaths than any other snake in West Africa. Despite its medical importance, there have been few investigations into the toxin composition of the venom of this viper. Here we describe the isolation of E. ocellatus venom gland cDNAs encoding a protein of 514 amino acids that showed 91% sequence similarity to Ecarin, a prothrombin-activating metalloproteinase from the venom of the East African viper, E. pyramidum leakeyi, that induces severe consumption coagulopathy. Structural similarities between the E. ocellatus metalloproteinase and analogues in venoms of related vipers suggest that antibodies raised to phylogenetically conserved E. ocellatus metalloproteinase domains may have potential for cross-specific and cross-generic neutralisation of analogous venom toxins. PMID:14602118

  20. The West African ebola virus disease epidemic 2014-2015: A commissioned review.

    PubMed

    Omilabu, S A; Salu, O B; Oke, B O; James, A B

    2016-01-01

    The first epidemic of Ebola haemorrhagic disease in West Africa is the largest and longest Ebola epidemic till date, where the outbreak notably involved three countries with distant spread to other countries. It has caused significant mortality, with reported case fatality rates of up to 70%. Data and relevant information were extracted from the review of majorly relevant publications/papers about the Ebola epidemic in West Africa and other previous outbreaks of Ebola virus (EBOV). As of 2016, with the epidemic under control, the World Health Organization has warned that flare-ups of the disease are likely to continue for some time as recently occurred in Sierra Leone and the on-going in Guinea. As this may not be the last outbreak of Ebola virus disease (EVD) in West Africa, there is a need to focus on diagnostic and research capacity required to curtail EVD with adequate measures for emergency preparedness and policies for innovative treatment strategies. PMID:27424613

  1. Bacillus anthracis Diversity and Geographic Potential across Nigeria, Cameroon and Chad: Further Support of a Novel West African Lineage

    PubMed Central

    Blackburn, Jason K.; Odugbo, Moses Ode; Van Ert, Matthew; O’Shea, Bob; Mullins, Jocelyn; Perrenten, Vincent; Maho, Angaya; Hugh-Jones, Martin; Hadfield, Ted

    2015-01-01

    Zoonoses, diseases affecting both humans and animals, can exert tremendous pressures on human and veterinary health systems, particularly in resource limited countries. Anthrax is one such zoonosis of concern and is a disease requiring greater public health attention in Nigeria. Here we describe the genetic diversity of Bacillus anthracis in Nigeria and compare it to Chad, Cameroon and a broader global dataset based on the multiple locus variable number tandem repeat (MLVA-25) genetic typing system. Nigerian B. anthracis isolates had identical MLVA genotypes and could only be resolved by measuring highly mutable single nucleotide repeats (SNRs). The Nigerian MLVA genotype was identical or highly genetically similar to those in the neighboring countries, confirming the strains belong to this unique West African lineage. Interestingly, sequence data from a Nigerian isolate shares the anthrose deficient genotypes previously described for strains in this region, which may be associated with vaccine evasion. Strains in this study were isolated over six decades, indicating a high level of temporal strain stability regionally. Ecological niche models were used to predict the geographic distribution of the pathogen for all three countries. We describe a west-east habitat corridor through northern Nigeria extending into Chad and Cameroon. Ecological niche models and genetic results show B. anthracis to be ecologically established in Nigeria. These findings expand our understanding of the global B. anthracis population structure and can guide regional anthrax surveillance and control planning. PMID:26291625

  2. Bacillus anthracis Diversity and Geographic Potential across Nigeria, Cameroon and Chad: Further Support of a Novel West African Lineage.

    PubMed

    Blackburn, Jason K; Odugbo, Moses Ode; Van Ert, Matthew; O'Shea, Bob; Mullins, Jocelyn; Perreten, Vincent; Perrenten, Vincent; Maho, Angaya; Hugh-Jones, Martin; Hadfield, Ted

    2015-01-01

    Zoonoses, diseases affecting both humans and animals, can exert tremendous pressures on human and veterinary health systems, particularly in resource limited countries. Anthrax is one such zoonosis of concern and is a disease requiring greater public health attention in Nigeria. Here we describe the genetic diversity of Bacillus anthracis in Nigeria and compare it to Chad, Cameroon and a broader global dataset based on the multiple locus variable number tandem repeat (MLVA-25) genetic typing system. Nigerian B. anthracis isolates had identical MLVA genotypes and could only be resolved by measuring highly mutable single nucleotide repeats (SNRs). The Nigerian MLVA genotype was identical or highly genetically similar to those in the neighboring countries, confirming the strains belong to this unique West African lineage. Interestingly, sequence data from a Nigerian isolate shares the anthrose deficient genotypes previously described for strains in this region, which may be associated with vaccine evasion. Strains in this study were isolated over six decades, indicating a high level of temporal strain stability regionally. Ecological niche models were used to predict the geographic distribution of the pathogen for all three countries. We describe a west-east habitat corridor through northern Nigeria extending into Chad and Cameroon. Ecological niche models and genetic results show B. anthracis to be ecologically established in Nigeria. These findings expand our understanding of the global B. anthracis population structure and can guide regional anthrax surveillance and control planning.

  3. The Impact of the Atlantic Cold Tongue on West African Monsoon Onset in Regional Model Simulations for 1998-2002

    NASA Technical Reports Server (NTRS)

    Druyan, Leonard M.; Fulakeza, Matthew B.

    2014-01-01

    The Atlantic cold tongue (ACT) develops during spring and early summer near the Equator in the Eastern Atlantic Ocean and Gulf of Guinea. The hypothesis that the ACT accelerates the timing of West African monsoon (WAM) onset is tested by comparing two regional climate model (RM3) simulation ensembles. Observed sea surface temperatures (SST) that include the ACT are used to force a control ensemble. An idealized, warm SST perturbation is designed to represent lower boundary forcing without the ACT for the experiment ensemble. Summer simulations forced by observed SST and reanalysis boundary conditions for each of five consecutive years are compared to five parallel runs forced by SST with the warm perturbation. The article summarizes the sequence of events leading to the onset of the WAM in the Sahel region. The representation of WAM onset in RM3 simulations is examined and compared to Tropical Rainfall Measuring Mission (TRMM), Global Precipitation Climatology Project (GPCP) and reanalysis data. The study evaluates the sensitivity of WAM onset indicators to the presence of the ACT by analysing the differences between the two simulation ensembles. Results show that the timing of major rainfall events and therefore theWAM onset in the Sahel are not sensitive to the presence of the ACT. However, the warm SST perturbation does increase downstream rainfall rates over West Africa as a consequence of enhanced specific humidity and enhanced northward moisture flux in the lower troposphere.

  4. Measuring pesticide ecological and health risks in West African agriculture to establish an enabling environment for sustainable intensification

    PubMed Central

    Jepson, P. C.; Guzy, M.; Blaustein, K.; Sow, M.; Sarr, M.; Mineau, P.; Kegley, S.

    2014-01-01

    We outline an approach to pesticide risk assessment that is based upon surveys of pesticide use throughout West Africa. We have developed and used new risk assessment models to provide, to our knowledge, the first detailed, geographically extensive, scientifically based analysis of pesticide risks for this region. Human health risks from dermal exposure to adults and children are severe enough in many crops to require long periods of up to three weeks when entry to fields should be restricted. This is impractical in terms of crop management, and regulatory action is needed to remove these pesticides from the marketplace. We also found widespread risks to terrestrial and aquatic wildlife throughout the region, and if these results were extrapolated to all similar irrigated perimeters in the Senegal and Niger River Basins, they suggest that pesticides could pose a significant threat to regional biodiversity. Our analyses are presented at the regional, national and village levels to promote regulatory advances but also local risk communication and management. Without progress in pesticide risk management, supported by participatory farmer education, West African agriculture provides a weak context for the sustainable intensification of agricultural production or for the adoption of new crop technologies. PMID:24535399

  5. Measuring pesticide ecological and health risks in West African agriculture to establish an enabling environment for sustainable intensification.

    PubMed

    Jepson, P C; Guzy, M; Blaustein, K; Sow, M; Sarr, M; Mineau, P; Kegley, S

    2014-04-01

    We outline an approach to pesticide risk assessment that is based upon surveys of pesticide use throughout West Africa. We have developed and used new risk assessment models to provide, to our knowledge, the first detailed, geographically extensive, scientifically based analysis of pesticide risks for this region. Human health risks from dermal exposure to adults and children are severe enough in many crops to require long periods of up to three weeks when entry to fields should be restricted. This is impractical in terms of crop management, and regulatory action is needed to remove these pesticides from the marketplace. We also found widespread risks to terrestrial and aquatic wildlife throughout the region, and if these results were extrapolated to all similar irrigated perimeters in the Senegal and Niger River Basins, they suggest that pesticides could pose a significant threat to regional biodiversity. Our analyses are presented at the regional, national and village levels to promote regulatory advances but also local risk communication and management. Without progress in pesticide risk management, supported by participatory farmer education, West African agriculture provides a weak context for the sustainable intensification of agricultural production or for the adoption of new crop technologies.

  6. Measuring pesticide ecological and health risks in West African agriculture to establish an enabling environment for sustainable intensification.

    PubMed

    Jepson, P C; Guzy, M; Blaustein, K; Sow, M; Sarr, M; Mineau, P; Kegley, S

    2014-04-01

    We outline an approach to pesticide risk assessment that is based upon surveys of pesticide use throughout West Africa. We have developed and used new risk assessment models to provide, to our knowledge, the first detailed, geographically extensive, scientifically based analysis of pesticide risks for this region. Human health risks from dermal exposure to adults and children are severe enough in many crops to require long periods of up to three weeks when entry to fields should be restricted. This is impractical in terms of crop management, and regulatory action is needed to remove these pesticides from the marketplace. We also found widespread risks to terrestrial and aquatic wildlife throughout the region, and if these results were extrapolated to all similar irrigated perimeters in the Senegal and Niger River Basins, they suggest that pesticides could pose a significant threat to regional biodiversity. Our analyses are presented at the regional, national and village levels to promote regulatory advances but also local risk communication and management. Without progress in pesticide risk management, supported by participatory farmer education, West African agriculture provides a weak context for the sustainable intensification of agricultural production or for the adoption of new crop technologies. PMID:24535399

  7. West African monsoon dynamics inferred from abrupt fluctuations of Lake Mega-Chad

    PubMed Central

    Armitage, Simon J.; Bristow, Charlie S.; Drake, Nick A.

    2015-01-01

    From the deglacial period to the mid-Holocene, North Africa was characterized by much wetter conditions than today. The broad timing of this period, termed the African Humid Period, is well known. However, the rapidity of the onset and termination of the African Humid Period are contested, with strong evidence for both abrupt and gradual change. We use optically stimulated luminescence dating of dunes, shorelines, and fluviolacustrine deposits to reconstruct the fluctuations of Lake Mega-Chad, which was the largest pluvial lake in Africa. Humid conditions first occur at ∼15 ka, and by 11.5 ka, Lake Mega-Chad had reached a highstand, which persisted until 5.0 ka. Lake levels fell rapidly at ∼5 ka, indicating abrupt aridification across the entire Lake Mega-Chad Basin. This record provides strong terrestrial evidence that the African Humid Period ended abruptly, supporting the hypothesis that the African monsoon responds to insolation forcing in a markedly nonlinear manner. In addition, Lake Mega-Chad exerts strong control on global biogeochemical cycles because the northern (Bodélé) basin is currently the world’s greatest single dust source and possibly an important source of limiting nutrients for both the Amazon Basin and equatorial Atlantic. However, we demonstrate that the final desiccation of the Bodélé Basin occurred around 1 ka. Consequently, the present-day mode and scale of dust production from the Bodélé Basin cannot have occurred before 1 ka, suggesting that its role in fertilizing marine and terrestrial ecosystems is either overstated or geologically recent. PMID:26124133

  8. West African monsoon dynamics inferred from abrupt fluctuations of Lake Mega-Chad.

    PubMed

    Armitage, Simon J; Bristow, Charlie S; Drake, Nick A

    2015-07-14

    From the deglacial period to the mid-Holocene, North Africa was characterized by much wetter conditions than today. The broad timing of this period, termed the African Humid Period, is well known. However, the rapidity of the onset and termination of the African Humid Period are contested, with strong evidence for both abrupt and gradual change. We use optically stimulated luminescence dating of dunes, shorelines, and fluviolacustrine deposits to reconstruct the fluctuations of Lake Mega-Chad, which was the largest pluvial lake in Africa. Humid conditions first occur at ∼ 15 ka, and by 11.5 ka, Lake Mega-Chad had reached a highstand, which persisted until 5.0 ka. Lake levels fell rapidly at ∼ 5 ka, indicating abrupt aridification across the entire Lake Mega-Chad Basin. This record provides strong terrestrial evidence that the African Humid Period ended abruptly, supporting the hypothesis that the African monsoon responds to insolation forcing in a markedly nonlinear manner. In addition, Lake Mega-Chad exerts strong control on global biogeochemical cycles because the northern (Bodélé) basin is currently the world's greatest single dust source and possibly an important source of limiting nutrients for both the Amazon Basin and equatorial Atlantic. However, we demonstrate that the final desiccation of the Bodélé Basin occurred around 1 ka. Consequently, the present-day mode and scale of dust production from the Bodélé Basin cannot have occurred before 1 ka, suggesting that its role in fertilizing marine and terrestrial ecosystems is either overstated or geologically recent.

  9. Lake Mega-Chad, a West African Monsoon indicator and tipping element

    NASA Astrophysics Data System (ADS)

    Armitage, Simon; Bristow, Charlie; Drake, Nick

    2015-04-01

    From the deglacial period to the mid-Holocene, North Africa was characterised by much wetter conditions than today. The broad timing of this period, termed the African Humid Period, is well known. However, the rapidity of the onset and termination of the African Humid Period are contested, with strong evidence for both abrupt and gradual change. We use optically stimulated luminescence dating of dunes, shorelines and fluvio-lacustrine deposits to reconstruct the fluctuations of Lake Mega-Chad, which was the largest pluvial lake in Africa. Humid conditions first occur at ~15 ka, followed by a return to relatively arid conditions. By 11.5 ka Lake Mega-Chad had reached a highstand, which persisted until 5.0 ka. Lake levels fell rapidly at 5 ka, indicating abrupt aridification across the entire Lake Mega-Chad Basin. This record provides strong terrestrial evidence that the African Humid Period ended abruptly, supporting the hypothesis that the African monsoon responds to insolation forcing in a markedly non-linear manner. In addition, Lake Mega-Chad exerts strong control on global biogeochemical cycles since the northern (Bodélé) basin is currently the World's greatest single dust source, and possibly an important source of limiting nutrients for both the Amazon basin and equatorial Atlantic. However, we demonstrate that the final desiccation of the Bodélé Basin occurred around 1 ka. Consequently, the present-day mode and scale of dust production from Bodélé Basin cannot have occurred prior to 1 ka, suggesting that its role in fertilizing marine and terrestrial ecosystems is either overstated or geologically recent.

  10. Reviving the African wolf Canis lupus lupaster in North and West Africa: a mitochondrial lineage ranging more than 6,000 km wide.

    PubMed

    Gaubert, Philippe; Bloch, Cécile; Benyacoub, Slim; Abdelhamid, Adnan; Pagani, Paolo; Djagoun, Chabi Adéyèmi Marc Sylvestre; Couloux, Arnaud; Dufour, Sylvain

    2012-01-01

    The recent discovery of a lineage of gray wolf in North-East Africa suggests the presence of a cryptic canid on the continent, the African wolf Canis lupus lupaster. We analyzed the mtDNA diversity (cytochrome b and control region) of a series of African Canis including wolf-like animals from North and West Africa. Our objectives were to assess the actual range of C. l. lupaster, to further estimate the genetic characteristics and demographic history of its lineage, and to question its taxonomic delineation from the golden jackal C. aureus, with which it has been considered synonymous. We confirmed the existence of four distinct lineages within the gray wolf, including C. lupus/familiaris (Holarctic wolves and dogs), C. l. pallipes, C. l. chanco and C. l. lupaster. Taxonomic assignment procedures identified wolf-like individuals from Algeria, Mali and Senegal, as belonging to C. l. lupaster, expanding its known distribution c. 6,000 km to the west. We estimated that the African wolf lineage (i) had the highest level of genetic diversity within C. lupus, (ii) coalesced during the Late Pleistocene, contemporaneously with Holarctic wolves and dogs, and (iii) had an effective population size of c. 80,000 females. Our results suggest that the African wolf is a relatively ancient gray wolf lineage with a fairly large, past effective population size, as also suggested by the Pleistocene fossil record. Unique field observations in Senegal allowed us to provide a morphological and behavioral diagnosis of the African wolf that clearly distinguished it from the sympatric golden jackal. However, the detection of C. l. lupaster mtDNA haplotypes in C. aureus from Senegal brings the delineation between the African wolf and the golden jackal into question. In terms of conservation, it appears urgent to further characterize the status of the African wolf with regard to the African golden jackal. PMID:22900047

  11. Reviving the African Wolf Canis lupus lupaster in North and West Africa: A Mitochondrial Lineage Ranging More than 6,000 km Wide

    PubMed Central

    Gaubert, Philippe; Bloch, Cécile; Benyacoub, Slim; Abdelhamid, Adnan; Pagani, Paolo; Djagoun, Chabi Adéyèmi Marc Sylvestre; Couloux, Arnaud; Dufour, Sylvain

    2012-01-01

    The recent discovery of a lineage of gray wolf in North-East Africa suggests the presence of a cryptic canid on the continent, the African wolf Canis lupus lupaster. We analyzed the mtDNA diversity (cytochrome b and control region) of a series of African Canis including wolf-like animals from North and West Africa. Our objectives were to assess the actual range of C. l. lupaster, to further estimate the genetic characteristics and demographic history of its lineage, and to question its taxonomic delineation from the golden jackal C. aureus, with which it has been considered synonymous. We confirmed the existence of four distinct lineages within the gray wolf, including C. lupus/familiaris (Holarctic wolves and dogs), C. l. pallipes, C. l. chanco and C. l. lupaster. Taxonomic assignment procedures identified wolf-like individuals from Algeria, Mali and Senegal, as belonging to C. l. lupaster, expanding its known distribution c. 6,000 km to the west. We estimated that the African wolf lineage (i) had the highest level of genetic diversity within C. lupus, (ii) coalesced during the Late Pleistocene, contemporaneously with Holarctic wolves and dogs, and (iii) had an effective population size of c. 80,000 females. Our results suggest that the African wolf is a relatively ancient gray wolf lineage with a fairly large, past effective population size, as also suggested by the Pleistocene fossil record. Unique field observations in Senegal allowed us to provide a morphological and behavioral diagnosis of the African wolf that clearly distinguished it from the sympatric golden jackal. However, the detection of C. l. lupaster mtDNA haplotypes in C. aureus from Senegal brings the delineation between the African wolf and the golden jackal into question. In terms of conservation, it appears urgent to further characterize the status of the African wolf with regard to the African golden jackal. PMID:22900047

  12. Dyed and Printed Textiles: Javanese Batik [and] Dutch Wax Prints [and] West African Adire. Third Edition.

    ERIC Educational Resources Information Center

    Burke, Sue

    Three booklets focusing on dyed and printed textile techniques of Java, West Africa, and the Netherlands describe historical and ethnographic materials as well as the development of particular technical traditions. Each section may be used alone or with either or both of the others. When used together, these booklets illustrate the…

  13. Change and Variation in Family Religious Language Policy in a West African Muslim Community

    ERIC Educational Resources Information Center

    Moore, Leslie C.

    2016-01-01

    This article examines variation in family religious language policy in a Muslim community in West Africa. Taking an ethnographically grounded case study approach, I situate families' choices with regards to their children's religious (language) education within the larger linguistic, social, and cultural context, focusing on new influences on…

  14. Molecular evolution of Azagny virus, a newfound hantavirus harbored by the West African pygmy shrew (Crocidura obscurior) in Côte d'Ivoire

    PubMed Central

    2011-01-01

    Background Tanganya virus (TGNV), the only shrew-associated hantavirus reported to date from sub-Saharan Africa, is harbored by the Therese's shrew (Crocidura theresae), and is phylogenetically distinct from Thottapalayam virus (TPMV) in the Asian house shrew (Suncus murinus) and Imjin virus (MJNV) in the Ussuri white-toothed shrew (Crocidura lasiura). The existence of myriad soricid-borne hantaviruses in Eurasia and North America would predict the presence of additional hantaviruses in sub-Saharan Africa, where multiple shrew lineages have evolved and diversified. Methods Lung tissues, collected in RNAlater®, from 39 Buettikofer's shrews (Crocidura buettikoferi), 5 Jouvenet's shrews (Crocidura jouvenetae), 9 West African pygmy shrews (Crocidura obscurior) and 21 African giant shrews (Crocidura olivieri) captured in Côte d'Ivoire during 2009, were systematically examined for hantavirus RNA by RT-PCR. Results A genetically distinct hantavirus, designated Azagny virus (AZGV), was detected in the West African pygmy shrew. Phylogenetic analysis of the S, M and L segments, using maximum-likelihood and Bayesian methods, under the GTR+I+Γ model of evolution, showed that AZGV shared a common ancestry with TGNV and was more closely related to hantaviruses harbored by soricine shrews than to TPMV and MJNV. That is, AZGV in the West African pygmy shrew, like TGNV in the Therese's shrew, did not form a monophyletic group with TPMV and MJNV, which were deeply divergent and basal to other rodent- and soricomorph-borne hantaviruses. Ancestral distributions of each hantavirus lineage, reconstructed using Mesquite 2.74, suggested that the common ancestor of all hantaviruses was most likely of Eurasian, not African, origin. Conclusions Genome-wide analysis of many more hantaviruses from sub-Saharan Africa are required to better understand how the biogeographic origin and radiation of African shrews might have contributed to, or have resulted from, the evolution of hantaviruses

  15. Spatial variability, structure and composition of crustose algal communities in Diadema africanum barrens

    NASA Astrophysics Data System (ADS)

    Sangil, Carlos; Sansón, Marta; Díaz-Villa, Tania; Hernández, José Carlos; Clemente, Sabrina; Afonso-Carrillo, Julio

    2014-12-01

    Crustose algal communities were studied in Diadema africanum urchin barrens around Tenerife (Canary Islands, NE Atlantic). A hierarchical nested sampling design was used to study patterns of community variability at different spatial scales (sectors, three sides of the island; sites within each sector, 5-10 km apart; stations within each site, 50-100 m apart). Although noncrustose species contributed the most to community richness, cover was dominated by crustose forms, like the coralline algae Hydrolithon farinosum, H. samoënse, H. onkodes, Neogoniolithon orotavicum and N. hirtum, and the phaeophycean Pseudolithoderma adriaticum. The structure of these communities showed high spatial variability, and we found differences in the structure of urchin barrens when compared across different spatial scales. Multivariate analysis showed that variability in community structure was related to the five environmental variables studied (wave exposure, urchin density, substrate roughness, productivity and depth). Wave exposure was the variable that contributed most to community variability, followed by urchin density and substrate roughness. Productivity and depth had limited influence. The effects of these variables differed depending on the spatial scale; wave exposure and productivity were the main variables influencing community changes at the largest scale (between different sectors of the island), while D. africanum density, roughness and depth were the most influential at medium and small scales.

  16. Solar quiet day ionospheric source current in the West African region

    NASA Astrophysics Data System (ADS)

    Obiekezie, Theresa N.; Okeke, Francisca N.

    2013-05-01

    The Solar Quiet (Sq) day source current were calculated using the magnetic data obtained from a chain of 10 magnetotelluric stations installed in the African sector during the French participation in the International Equatorial Electrojet Year (IEEY) experiment in Africa. The components of geomagnetic field recorded at the stations from January-December in 1993 during the experiment were separated into the source and (induced) components of Sq using Spherical Harmonics Analysis (SHA) method. The range of the source current was calculated and this enabled the viewing of a full year's change in the source current system of Sq.

  17. Solar quiet day ionospheric source current in the West African region.

    PubMed

    Obiekezie, Theresa N; Okeke, Francisca N

    2013-05-01

    The Solar Quiet (Sq) day source current were calculated using the magnetic data obtained from a chain of 10 magnetotelluric stations installed in the African sector during the French participation in the International Equatorial Electrojet Year (IEEY) experiment in Africa. The components of geomagnetic field recorded at the stations from January-December in 1993 during the experiment were separated into the source and (induced) components of Sq using Spherical Harmonics Analysis (SHA) method. The range of the source current was calculated and this enabled the viewing of a full year's change in the source current system of Sq. PMID:25685434

  18. The Sensitivity of WRF Daily Summertime Simulations over West Africa to Alternative Parameterizations. Part 1: African Wave Circulation

    NASA Technical Reports Server (NTRS)

    Noble, Erik; Druyan, Leonard M.; Fulakeza, Matthew

    2014-01-01

    The performance of the NCAR Weather Research and Forecasting Model (WRF) as a West African regional-atmospheric model is evaluated. The study tests the sensitivity of WRF-simulated vorticity maxima associated with African easterly waves to 64 combinations of alternative parameterizations in a series of simulations in September. In all, 104 simulations of 12-day duration during 11 consecutive years are examined. The 64 combinations combine WRF parameterizations of cumulus convection, radiation transfer, surface hydrology, and PBL physics. Simulated daily and mean circulation results are validated against NASA's Modern-Era Retrospective Analysis for Research and Applications (MERRA) and NCEP/Department of Energy Global Reanalysis 2. Precipitation is considered in a second part of this two-part paper. A wide range of 700-hPa vorticity validation scores demonstrates the influence of alternative parameterizations. The best WRF performers achieve correlations against reanalysis of 0.40-0.60 and realistic amplitudes of spatiotemporal variability for the 2006 focus year while a parallel-benchmark simulation by the NASA Regional Model-3 (RM3) achieves higher correlations, but less realistic spatiotemporal variability. The largest favorable impact on WRF-vorticity validation is achieved by selecting the Grell-Devenyi cumulus convection scheme, resulting in higher correlations against reanalysis than simulations using the Kain-Fritch convection. Other parameterizations have less-obvious impact, although WRF configurations incorporating one surface model and PBL scheme consistently performed poorly. A comparison of reanalysis circulation against two NASA radiosonde stations confirms that both reanalyses represent observations well enough to validate the WRF results. Validation statistics for optimized WRF configurations simulating the parallel period during 10 additional years are less favorable than for 2006.

  19. Geophysical basin structure of the Cotonou (Dahomey/Benin) basin, West African Gulf of Guinea

    SciTech Connect

    Babalola, O.O. )

    1990-05-01

    The frontier Cotonou basin (or Dahomey/Benin embayment), situated west of the prolific Niger Delta basin, appears from seismic, gravity, and aeromagnetic interpretation, as a series of grabens and troughs confined on the west and east by the Romanche and the Chain fracture zones, respectively. The Keta trough of the western basin rim was formed by a 2700-m southeasterly downthrow of the Adina fault. This trough is separated by a north-northeasterly fault from the Lome-Anecho gravity high. Eastward, the arcuate Allada-Adjohon trough is abutted on its southern flank by the northwest-trending Nokue-Afowo trough and separated from the northwesterly Ikorodu trough by the 50-km-wide aeromagnetically inferred ro-Otta ridge. The Ikorodu trough is adjoined on the northwest by the Aiyetoro trough and on the southeast by the Yemoja offshore graben trending east northeast as the Seme oil-field structural trend. North of the regional northeasterly axial, gravity positive, structural divide (the continental precursor of the Charcot fracture zone) a series of half-grabens (notably the Aplahoue, Bohicon, and Keiou troughs), normal faulted eastward and downthrown in the west, dominate the landward western rim of the Cotonou basin. Graben-bounding faults control the upper valleys of the basin drainage, converge toward the regional intrabasin structural trend and continue into the Fenyi-koe fault and the Charcot fracture zone. These faults resulted from brittle dextral shear of continental crust oblique to local, preexisting north-northeast structural trends. In the eastern basin rim, preexisting north-northwest structural trends influenced the shearing stress regime to generate small, shallow, structurally bounded, east-northeast- and north-northwest trending grabens.

  20. Trends and Variability in Pastoral Resources in the West African Sahel

    NASA Astrophysics Data System (ADS)

    Hanan, N. P.

    2014-12-01

    The geography of water and nutrients in the savannas of West Africa has shaped the development of a system of migratory cattle movements ("transhumance") in which herds travel north during the rainy season to graze the nutritious grasslands of the Sahel and return south in the dry season to graze in fallow lands and on agricultural residue. Cattle in this system gain most of their body mass while grazing in the Sahel and frequently lose mass on their dry season range. The Sahel is, therefore, at the heart of extensive livestock production systems in West Africa. However, there is increasing concern regarding how climate change will impact the region, while human population growth and economic development require increased agricultural and livestock production. The future for pastoral production systems in West Africa is, therefore, uncertain. This presentation combines remote sensing of vegetation structure and phenology with a watershed-scale tree-grass ecohydrology model, to explore how key resources for Sahelian pastoralist communities (forage and surface water for livestock, woody biomass for fuel) respond to climate variability and extreme events, conditioned by human management of grazing, fire and fuel-wood harvest. Mortality of woody species and loss of herbaceous cover during the Sahelian droughts of the 1970's and 1980's significantly perturbed vegetation dynamics and ecohydrological interactions, perturbations from which the region is still recovering. The re-greening and reforestation of the Sahel reported by many authors is, in part, an expression of this recovery. Future trajectories of change in pastoral resources in the Sahel, in particular forage availability and drinking water, are explored using climate change ensembles.

  1. Tectonic evolution of the Oudalan-Gorouol greenstone belt in NE Burkina Faso and Niger, West African craton.

    NASA Astrophysics Data System (ADS)

    Tshibubudze, Asinne; Hein, Kim A. A.

    2010-05-01

    The Oudalan-Gorouol Greenstone Belt (OGGB) forms part of the Palaeoproterozoic as the Baoulé-Mossi domain of the West African Craton (WAC) and hosts gold deposits at Essakane, Gossey, Korizena, and Falagountou in NE Burkina Faso, and Kossa goldfield in Niger. The Birimian supracrustal sequences in the OGGB are dominated by meta-volcanoclastic greywacke intercalated meta-conglomerate, siltstone and shale, carbonate (dolomite) and volcanic units pillow basalts). The belt is surrounded by plutonic rocks including granite, TTG suite granitoids and granite gneiss. The sequences where subjected to two phases of deformation, and several phases of contact metamorphosed to hornblende-hornfels facies during emplacement of pyroxenite-gabbro-norite, granodiorite-tonalite and gabbro dykes and porphyritic sills. The OGGB is bounded and/or crosscut by several major NNE to NE-trending shear zones including the steeply east-dipping Markoye Shear Zone (western margin of the OGGB), Tin Takanet-Bellekcire Shear Zone, Dori Shear Zone, Kargouna Shear Zone, Takabougou Shear Zone, and Bom Kodjelé Shear Zone (transects the centre of the OGGB). The structures were readily identified using LANDSAT, Aster, aeromagnetic and RTP magnetic data, with follow-up strategic mapping, highlighting the value of interpreting geophysical and remotely sensed data in regional mapping in Burkina Faso and Niger. Structural studies completed in 2007 adjacent to the Essakane gold mine indicated that the NE-trending, first-order crustal-scale Markoye Shear Zone (MSZ) has undergone at least two phases of reactivation concomitant to two phases of regional deformation (Tshibubudze et al., 2009). The first phase of deformation, D1, resulted in the formation of NNW-NW trending folds and thrusts during dextral-reverse displacement on the MSZ. The deformation predates the Eburnean Orogeny is termed the Tangaean Event (meaning low hills in the Moré language of Burkina Faso) and is tentatively dated at ca. 2170

  2. Haematological and serum biochemical parameters of West African Dwarf goats fed dried cassava leaves-based concentrate diets.

    PubMed

    Oni, Adebayo Olusoji; Arigbede, Oluwasanmi Moses; Sowande, Olusiji Sunday; Anele, Uchenna Young; Oni, Oluwakemi Oluremilekun; Onwuka, Chryss Friday Ijeoma; Onifade, Olufemi Sunday; Yusuf, Kafayat Omowumi; Dele, Peter Aniwe; Aderinboye, Ronke Yemisi

    2012-03-01

    The study was conducted to investigate the effects of feeding different levels of dried cassava leaves at 0%, 20%, 40% and 60%, respectively, using guinea grass as basal feed, on the haematological and serum biochemical parameters of West African Dwarf (WAD) goats. The study lasted for 116 days during which haematological and serum biochemical parameters were monitored in 40 male goats before and after, using a completely randomized design. At the start of the experiment, packed cell volume (PCV) ranged from 21.5% to 25.5% while haemoglobin concentration (Hb) and RBC significantly (P < 0.01) ranged from 7.3 to 8.6 g/dl and 10.4 to 13.2 × 10(12)/l, respectively. White blood cells reduced significantly (P < 0.05)) from 16.4 to 11.7 × 10(9)/l) as dried cassava leaves increased in the diets. At the end of the trial, there was a slight increase in the values of PCV and Hb in the diets (P > 0.05). Lymphocyte reduced significantly (P < 0.05) from 50.0% to 63.5% in the diets. Neutrophils, however, increased (P > 0.05) at the 0% to 40% levels and reduced at the 60% level of dried cassava leaves inclusion. At the start of the experiment, values for glucose significantly (P < 0.05) ranged from 40.1 to 56.0 mg/dl. Total protein and albumin values ranged significantly (P < 0.05) from 56.0 to 68.5 g/dl and 30.6 to 38.4 g/dl, respectively. At the end of the experiment, serum creatinine increased significantly (P < 0.05) as the level of dried cassava leaves increased from 0% to 60% in the diets. The study revealed that inclusion of dried cassava leaves in the diets of West African Dwarf goats had no deleterious effects on the haematological and serum biochemical parameters of WAD goats and could therefore be included in ruminant diets up to 60%.

  3. Leucaena and dried poultry waste improve the performance of West African Dwarf sheep on a grass diet.

    PubMed

    Agbor, Euphresia Besongtakor; Ndamukong, Kenneth Jacob Ngoh; Pamo, Etienne Tendonkeng

    2013-04-01

    This study investigated the effects on digestibility and growth when West African Dwarf (WAD) sheep were fed a basal diet of Tripsacum laxum with Leucaena leucocephala or dried poultry waste as supplement. Fifteen WAD sheep (12 rams and 3 ewes) were randomly allocated to three dietary treatments of 5 animals each, namely T1-basal diet of chopped T. laxum (control), T2-basal diet plus dried poultry waste, and T3-basal diet plus L. leucocephala. Animals had access to drinking water and a mineral mix ad libitum. They were weighed weekly after a 2-week adaptation period, for a duration of 12 weeks. At the end of the feeding trial, three rams randomly selected from each treatment group were used for the digestibility study. Results revealed that average daily intake of L. leucocephala (350.0 ± 0.3 g/animal) was higher than that of dried poultry waste (260.0 ± 0.1 g/animal). The supplemented groups, T2 and T3, gained 21.4 and 31.0 g daily respectively, while animals of the control group (T1) lost 6.0 g daily. There was a significant difference (P<0.01) in dry matter intake between the control and supplemented groups, with T2 recording the highest intake. Organic matter intake of treatment 3 was significantly (P<0.01) higher than that of T1 and T2. The differences in crude fibre (CF) ingestion between T2 and T1 as well as T3 and T1 were significant (P<0.01), with the highest ingestion of CF occurring in T1. The dry matter digestibility of the supplemented groups was significantly higher (P<0.05) than that of the control. The organic matter digestibility of T2 and T3, as well as T1 and T3 were significantly different (P<0.05), being highest in T3 (77.0 ± 2.1 %) and lowest in T2 (58.1 ± 1.0 %) It was concluded from the study that T. laxum can be better utilized in West African Dwarf sheep when supplemented with dried poultry waste or L. leucocephala.

  4. Leucaena and dried poultry waste improve the performance of West African Dwarf sheep on a grass diet.

    PubMed

    Agbor, Euphresia Besongtakor; Ndamukong, Kenneth Jacob Ngoh; Pamo, Etienne Tendonkeng

    2013-04-01

    This study investigated the effects on digestibility and growth when West African Dwarf (WAD) sheep were fed a basal diet of Tripsacum laxum with Leucaena leucocephala or dried poultry waste as supplement. Fifteen WAD sheep (12 rams and 3 ewes) were randomly allocated to three dietary treatments of 5 animals each, namely T1-basal diet of chopped T. laxum (control), T2-basal diet plus dried poultry waste, and T3-basal diet plus L. leucocephala. Animals had access to drinking water and a mineral mix ad libitum. They were weighed weekly after a 2-week adaptation period, for a duration of 12 weeks. At the end of the feeding trial, three rams randomly selected from each treatment group were used for the digestibility study. Results revealed that average daily intake of L. leucocephala (350.0 ± 0.3 g/animal) was higher than that of dried poultry waste (260.0 ± 0.1 g/animal). The supplemented groups, T2 and T3, gained 21.4 and 31.0 g daily respectively, while animals of the control group (T1) lost 6.0 g daily. There was a significant difference (P<0.01) in dry matter intake between the control and supplemented groups, with T2 recording the highest intake. Organic matter intake of treatment 3 was significantly (P<0.01) higher than that of T1 and T2. The differences in crude fibre (CF) ingestion between T2 and T1 as well as T3 and T1 were significant (P<0.01), with the highest ingestion of CF occurring in T1. The dry matter digestibility of the supplemented groups was significantly higher (P<0.05) than that of the control. The organic matter digestibility of T2 and T3, as well as T1 and T3 were significantly different (P<0.05), being highest in T3 (77.0 ± 2.1 %) and lowest in T2 (58.1 ± 1.0 %) It was concluded from the study that T. laxum can be better utilized in West African Dwarf sheep when supplemented with dried poultry waste or L. leucocephala. PMID:23224820

  5. Trace gas emissions to the atmosphere by biomass burning in the west African savannas

    NASA Technical Reports Server (NTRS)

    Frouin, Robert J.; Iacobellis, Samuel F.; Razafimpanilo, Herisoa; Somerville, Richard C. J.

    1994-01-01

    Savanna fires and atmospheric carbon dioxide (CO2) detection and estimating burned area using Advanced Very High Resolution Radiometer_(AVHRR) reflectance data are investigated in this two part research project. The first part involves carbon dioxide flux estimates and a three-dimensional transport model to quantify the effect of north African savanna fires on atmospheric CO2 concentration, including CO2 spatial and temporal variability patterns and their significance to global emissions. The second article describes two methods used to determine burned area from AVHRR data. The article discusses the relationship between the percentage of burned area and AVHRR channel 2 reflectance (the linear method) and Normalized Difference Vegetation Index (NDVI) (the nonlinear method). A comparative performance analysis of each method is described.

  6. On the cause of the correlation between West African dust outbreaks and Sahelian rainfall

    NASA Astrophysics Data System (ADS)

    Evan, A. T.; Flamant, C.

    2014-12-01

    A large body of work has shown, using both in-situ data and remote sensing products, that there is a negative correlation between Sahelian rainfall and African dust outbreaks that traverse the tropical Atlantic. One theory for this relationship is that drying out of the Sahel results in the activation of new dust sources. However, there is no direct evidence to support this theory, nor has any modeling study conclusively shown this to be the case. Another theory is that changes in the regional circulation associated with wet and dry periods of the Sahel results in this inverse proportionality between dust and rainfall. A new modeling study has provided compelling evidence to show that this latter theory may be closer to the truth. Here we show that the recent trends in dust from western Africa can be explained by examining changes in surface winds over source regions near the Air, Adrar, and Ouaddai mountains, and the Bodélé depression. Our analysis shows that the recent trends in dust are due to a slow down of the surface winds over the Air and Adrar source regions, and that this is a result of the simultaneous intensification of the low-level circulation of the Sahara Heat Low. Thus, coupling of Sahel rainfall and the Sahara Heat Low results in the correlation between dust and Sahel drought. Furthermore, we estimate future changes in dust from climate models via analysis of modeled changes in wind speeds over these regions. We find that one model in the Fifth Phase Coupled Model Intercomparison Project, the GFDL-CM3, accurately represents historical changes in wind speeds over these key source regions, and that in future scenarios this model shows a large and statistically significant increase in surface windspeeds over the Bodélé, suggesting an increase in African dust emission throughout the 21st Century.

  7. The impact of land use on the net ecosystem CO2 exchanges in the West African Sudanian Savannas

    NASA Astrophysics Data System (ADS)

    Mauder, Matthias; Quansah, Emmanuel; Annor, Thompson; Balogun, Ahmed A.; Amekudzi, Leonard K.; Bliefernicht, Jan; Heinzeller, Dominikus; Kunstmann, Harald

    2016-04-01

    The land surface in West Africa has been considerably changed within the past decade due to various anthropogenic measures such as an increased agricultural activity. However, the impact of these land use changes on land-atmosphere exchange processes such as net ecosystems exchange is not well known for this highly vulnerable region. To tackle this problem, the effects of land use on the net ecosystem exchange of CO2 (NEE) along a transect of three contrasting ecosystems have been investigated on seasonal and annual time scales using the Eddy Covariance method. The ecosystems were grassland (GL), a mixture of fallow and cropland (CR) in the Upper East Region of Ghana, and a nature reserve (NR) near Pô in the Nahouri Province of Burkina Faso. The results for January to December 2013 showed that the ecosystems of the three sites served as net sinks of CO2 during the rainy season (May to October) and net sources of CO2 during the dry season (November to April). However, NR was a net sink of CO2 during the wet to dry transition period (November to December). On an annual timescale, only NR served as a net sink of CO2 from the atmosphere into the ecosystem, while the others were net sources of CO2 into the atmosphere. Furthermore, the study revealed that the three contrasting ecosystems responded to environmental and physiological factors based on the ecosystem functional types. This suggests that land use and land use management may play a significant role in the diurnal to annual sequestration and efflux patterns of NEE and its composite fluxes, gross primary production (GPP) and ecosystem respiration (ER), over the West African Sudanian Savannas.

  8. Genome-wide search for susceptibility genes to type 2 diabetes in West Africans: potential role of C-peptide.

    PubMed

    Chen, Guanjie; Adeyemo, Adebowale; Zhou, Jie; Chen, Yuanxiu; Huang, Hanxia; Doumatey, Ayo; Lashley, Kerrie; Agyenim-Boateng, Kofi; Eghan, Benjamin A; Acheampong, Joseph; Fasanmade, Olufemi; Johnson, Thomas; Okafor, Godfrey; Oli, Johnnie; Amoah, Albert; Rotimi, Charles

    2007-12-01

    C-peptide is a substance that the pancreas releases into the circulation in equimolar amounts to insulin and has demonstrated important physiological effects which relate to the vascular field, in particular the microcirculation. For this analysis, we included 321 full and 36 half sibling pairs affected with type 2 diabetes (T2D) from West Africa. A genome-wide panel of 390 tri-nucleotide and tetra-nucleotide repeats with an average distance of 8.9 cM was performed on a total of 691 persons. Variance components based on multipoint linkage approach as implemented in SOLAR were performed for log C-peptide. Significant linkage evidences were observed on 10q23 at D10S2327 with a LOD score of 4.04 (nominal p-value=0.000008, empirical p-value=0.0004); and on 4p15 at D4S2632 with a LOD score of 3.48 (nominal p-value=0.000031, empirical p-value=0.0013). Other suggestive evidence of linkage were observed on 15q14 at D15S659 with a LOD score 2.41 (nominal p-value=0.000435, empirical p-value=0.0068), and on 18p11 near D18S976 with a LOD score 2.18 (nominal p-value=0.000771 and empirical p-value=0.0094). Interestingly, five positional candidate genes for diabetes and related complications are located in our linkage region (the pituitary adenylate cyclase activating polypeptide (PACAP in 18p11); the peroxisome proliferator-activated receptor gamma coactivator 1 (PPARGC1 in 4p15); PTEN, PPP1R5, and IDE located in 10q23. In conclusion, we identified four major genetic loci (10q23, 4p15, 15q14, and 18p11) influencing C-peptide concentration in West Africans with T2D.

  9. North African dust deposition and hydroclimate over the last 60 ka: A combined view from the east and west of the continent

    NASA Astrophysics Data System (ADS)

    Kinsley, C. W.; McGee, D.; Bradtmiller, L. I.; Tierney, J. E.; Winckler, G.; Stuut, J. B. W.; deMenocal, P. B.

    2014-12-01

    Past changes in atmospheric circulation and hydroclimate over North Africa can be explored by reconstructing eolian dust accumulation in both East and West African margin sediments. Recent high-resolution reconstructions of dust deposition from West Africa (1) indicate dramatic changes in North African dust emissions over the last 20 ka, with comparable results to those found in the terrigenous accumulation rates at nearby ODP Hole 658C (2). A high-resolution record of aridity from East Africa using δDwax indicates dramatic changes in hydroclimate over the past 40 ka (3). The records show similar trends with arid conditions/high dust emissions seen during the Last Glacial Maximum, the Younger Dryas and Heinrich Event 1 (H1), and the wettest conditions of the past 40,000 years with accompanying low dust emissions during the African Humid Period. This study has two goals: 1) Extend the dust flux and terrigeneous accumulation records from West Africa back to 35 ka and 60 ka respectively, to provide quantitative estimates of the magnitude of eolian deposition changes associated with previous Heinrich Stadials (H2 to H6) and summer insolation minima/maxima; 2) Construct a high-resolution record of eolian dust accumulation rates off the East African margin over the past 20 ka using the same sample material as (3) allowing quantitative estimates of the magnitude of dust flux changes associated with abrupt changes in hydroclimate and provide a direct comparison of dust flux and δDwax. The combination of these study areas from both sides of the African continent, and comparison of the dust and leaf wax proxies promises to provide a more complete picture of hydroclimate changes accompanying orbital- and millennial-scale climate changes in North Africa over the last 60,000 years. 1. EPSL 371-372, 163-176. 2. Paleoceanography 21, PA4203. 3. Science 342, 843-846.

  10. Characterization of the casein gene complex in West African goats and description of a new alpha(s1)-casein polymorphism.

    PubMed

    Caroli, A; Chiatti, F; Chessa, S; Rignanese, D; Ibeagha-Awemu, E M; Erhardt, G

    2007-06-01

    The analysis of casein polymorphisms was carried out in West Africa goat populations: Red Sokoto (n = 57), West African Dwarf Nigeria (n = 27), West African Dwarf Cameroon (n = 39), and Borno (n = 37). The 4 casein genes alpha(s1) (CSN1S1), beta (CSN2), alpha(s2) (CSN1S2), and kappa (CSN3) were typed at the DNA level. No null alleles were found in any of the genes analyzed. A PCR single-strand conformation polymorphism method was implemented for the identification of CSN1S1*F allele simultaneously with A/0(1), B/E, N and the new allele. The allele differed from CSN1S1*B by a synonymous transversion TCG-->TCT in the codon corresponding to Ser(66) of the mature protein. The new allele, named CSN1S1*B', occurred at a high frequency in all the populations, ranging from 0.295 (West African Dwarf Cameroon) to 0.405 (Borno). A greater frequency was found for alleles associated with high alpha(s1)-casein quantity, as has already been observed in the goat populations from the Mediterranean area. The intermediate E allele occurred only in the Red Sokoto and at a low frequency. The faint F allele occurred in 3 populations at frequencies lower than 0.03. Linkage disequilibrium occurred in all the populations, with highly significant differences in Borno, Red Sokoto, and West Africa Dwarf Nigeria, and significant differences in West Africa Dwarf Cameroon. Only 10 haplotypes showed frequencies > or =0.05 in at least 1 of the 4 populations considered, and the overall frequency was >0.1 only for 4 haplotypes: BAAB, B'ACA, ACAB, and BACA (in the order CSN1S1-CSN2-CSN1S2-CSN3). Haplotype BAAB, postulated as an ancestral haplotype in previous studies, was the most common haplotype in all breeds except Borno, where B'ACA was predominant. The results obtained are of considerable significance given that very little information exists on the subject for African goats. The high frequency of strong alleles in the calcium-sensitive caseins as well as the high linkage disequilibrium found

  11. “911” among West African immigrants in New York City: A qualitative study of parents’ disciplinary practices and their perceptions of child welfare authorities

    PubMed Central

    Rasmussen, Andrew; Akinsulure-Smith, Adeyinka; Chu, Tracy; Keatley, Eva

    2012-01-01

    Immigrant parents’ perceptions of child protective services may have important implications for their engagement in public institutions that are central to their children’s well being. The current study examined West African immigrants’ perceptions of child welfare authorities and the role of disciplining and monitoring in these communities’ meaning making. A multiethnic group of 59 West African immigrants (32 parents and 27 adolescent children) living in the United States were interviewed in 18 focus groups and eight individual interviews between December 2009 and July 2010. Data were analyzed using a grounded theory approach; strategies for rigor included triangulation (multiple interview formats, varied composition of groups, multiple coders for each transcript), verification (follow-up interviewing, feedback to community-based organizations), and auditability. Primary among parents’ concerns were “911” (used to refer to the police and child protective authorities), the loss of collective child monitoring networks, and threats to their children posed by “American” values and neighborhood violence. Children were concerned with parents’ close monitoring that resulted in boredom and a sense that parents did not recognize them for adhering to their families’ values. Feedback from CBOs suggested that parents got their information about child protective policies from children but that although misinformed they were accurate in their negative assessment of contact. Not unlike in other urban populations, West African immigrants’ disciplinary tactics are instrumental, oriented towards protecting their children from the multiple dangers perceived in their surroundings, but may also put them at risk for contact with child protective services. Results suggest that “911” results from a “loss spiral” (Hobfoll, 1989) that begins as West Africans resettle without collective child monitoring networks, leading to increased concern for their

  12. "911" Among West African immigrants in New York City: a qualitative study of parents' disciplinary practices and their perceptions of child welfare authorities.

    PubMed

    Rasmussen, Andrew; Akinsulure-Smith, Adeyinka; Chu, Tracy; Keatley, Eva

    2012-08-01

    Immigrant parents' perceptions of child protective services may have important implications for their engagement in public institutions that are central to their children's well being. The current study examined West African immigrants' perceptions of child welfare authorities and the role of disciplining and monitoring in these communities' meaning making. A multiethnic group of 59 West African immigrants (32 parents and 27 adolescent children) living in the United States were interviewed in 18 focus groups and eight individual interviews between December 2009 and July 2010. Data were analyzed using a grounded theory approach; strategies for rigor included triangulation (multiple interview formats, varied composition of groups, multiple coders for each transcript), verification (follow-up interviewing, feedback to community-based organizations), and auditability. Primary among parents' concerns were "911" (used to refer to the police and child protective authorities), the loss of collective child monitoring networks, and threats to their children posed by "American" values and neighborhood violence. Children were concerned with parents' close monitoring that resulted in boredom and a sense that parents did not recognize them for adhering to their families' values. Feedback from CBOs suggested that parents got their information about child protective policies from children but that although misinformed they were accurate in their negative assessment of contact. Not unlike in other urban populations, West African immigrants' disciplinary tactics are instrumental, oriented toward protecting their children from the multiple dangers perceived in their surroundings, but may also put them at risk for contact with child protective services. Results suggest that "911" results from a "loss spiral" (Hobfoll, 1989) that begins as West Africans resettle without collective child monitoring networks, leading to increased concern for their children's safety, and interacting with

  13. On some sea cucumbers (Echinodermata: Holothuroidea) from off the south and west coasts of South Africa collected by the South African Environmental and Observation Network (SAEON).

    PubMed

    Thandar, Ahmed S; Rambaran, Ryan

    2015-08-07

    Twenty four specimens of holothuroids recently received from the South African Environmental and Observation Network (SAEON), collected from off the south and west coasts of South Africa, are herein recorded and/or described. The specimens comprise eight nominal and one indeterminate species and represent both shallow-water and deep-sea forms, distributed from Plettenberg Bay to just north of Lambert's Bay in the Western Cape Province. There are no new species but two new records for the South African region and extensions of horizontal and bathymetric distributions of the other species. Additions to the South African fauna are Zygothuria lactea (Théel, 1886) and Synallactes cf. challengeri (Théel, 1886). The paper also contains the first definite record of Thyone venusta Selenka, 1868, originally described from the Red Sea. Distribution ranges of the following species have been altered Synallactes viridilimus Cherbonnier, 1952; S. mollis Cherbonnier, 1952 and Psuedostichopus langeae Thandar, 2009.

  14. Race, genetic West African ancestry, and prostate cancer prediction by prostate-specific antigen in prospectively screened high-risk men.

    PubMed

    Giri, Veda N; Egleston, Brian; Ruth, Karen; Uzzo, Robert G; Chen, David Y T; Buyyounouski, Mark; Raysor, Susan; Hooker, Stanley; Torres, Jada Benn; Ramike, Teniel; Mastalski, Kathleen; Kim, Taylor Y; Kittles, Rick

    2009-03-01

    "Race-specific" prostate-specific antigen (PSA) needs evaluation in men at high risk for prostate cancer for optimizing early detection. Baseline PSA and longitudinal prediction for prostate cancer were examined by self-reported race and genetic West African (WA) ancestry in the Prostate Cancer Risk Assessment Program, a prospective high-risk cohort. Eligibility criteria were age 35 to 69 years, family history of prostate cancer, African American race, or BRCA1/2 mutations. Biopsies were done at low PSA values (<4.0 ng/mL). WA ancestry was discerned by genotyping 100 ancestry informative markers. Cox proportional hazards models evaluated baseline PSA, self-reported race, and genetic WA ancestry. Cox models were used for 3-year predictions for prostate cancer. Six hundred forty-six men (63% African American) were analyzed. Individual WA ancestry estimates varied widely among self-reported African American men. Race-specific differences in baseline PSA were not found by self-reported race or genetic WA ancestry. Among men with > or =1 follow-up visit (405 total, 54% African American), 3-year prediction for prostate cancer with a PSA of 1.5 to 4.0 ng/mL was higher in African American men with age in the model (P = 0.025) compared with European American men. Hazard ratios of PSA for prostate cancer were also higher by self-reported race (1.59 for African American versus 1.32 for European American, P = 0.04). There was a trend for increasing prediction for prostate cancer with increasing genetic WA ancestry. "Race-specific" PSA may need to be redefined as higher prediction for prostate cancer at any given PSA in African American men. Large-scale studies are needed to confirm if genetic WA ancestry explains these findings to make progress in personalizing prostate cancer early detection.

  15. A Record of Early to Middle Holocene Hydroclimate Variability from the West African Sahel

    NASA Astrophysics Data System (ADS)

    McIntosh, R.; Douglas, P. M.; Warren, C.; Meyers, S. R.; Coutros, P.; Park, D. P.

    2011-12-01

    The African Humid Period (ca. 14.8 to 5.5 ka) is an interval of wet climates across northwest Africa, with evidence for widespread lake basins and savannah vegetation in areas that are now desert. There are few high-resolution continental records of hydrologic variability during the African humid period however. In particular, it remains uncertain how periods of north Atlantic climate variability were expressed in northwest Africa. We present results from a 5.4 meter sediment core from Lake Fati in northern Mali (16.29° N, 3.71° W), which represents the first lake sediment core from the western Sahel. The Lake Fati core contains a continuous record of lake mud from 10.43 to 4.66 kyr BP. Centimeter scale XRF scanning indicates strong covariation between iron, calcium, manganese and phosphorous abundance due to enrichment of these elements during periods of enhanced deposition of authigenic siderite. Preliminary oxygen isotope measurements indicate that authigenic siderite δ18O values are positively correlated with Fe counts, suggesting that siderite deposition increased during drier periods with greater evaporation of lake waters. These drying events occurred on decadal to centennial time scales, with higher-frequency variability during the early Holocene. Peaks in zirconium and titanium abundance coincide with some of the inferred dry periods, suggesting that deposition of aeolian silt coincided with periods of increased evaporation of lake water. A roughly 30 year interval of sand deposition at ~8.33 kyr BP suggests major drying and activation of aeolian sand deposition. This abrupt climate change could be related to the 8.2 ka event in the North Atlantic; further efforts to refine the sediment core age model will constrain the relationship of this rapid drying to abrupt climate change in the North Atlantic. Aluminum and silicon counts co-vary for much of the lake Fati record, and are related to input of terrigenous sediment, primarily during seasonal flooding

  16. Crustal evolution and the eclogite to granulite phase transition in xenoliths from the West African Craton

    NASA Technical Reports Server (NTRS)

    Haggerty, S. E.; Hills, D. V.; Toft, P. B.

    1988-01-01

    A suite of eclogite and granulite facies xenoliths from kimberlite pipes in the Archean Man Shield of West Africa is described. The xenoliths include lithologies ranging in composition from komatiite to anorthosite and appear to be geochemically, petrologically, and geophysically related. The suite may represent fractionation of felsic material separated from ancient mantle and added to early Archean crust. The samples can be used to define a xenolith geotherm, which may represent an ancient episode of high heat flow. The samples also imply that the crust-mantle boundary is a gradational and possibly interlayered geochemical, mineralogical, and seismic transition. It is speculated that the depleted subcontinental mantle required by diamond bearing coalescence of smaller depletion cells formed by extraction of ancient crustal components. These depleted zones are surrounded by fertile asthenospheric mantle, which may have given rise to later flood basalts such as the Karroo and Parana Provinces.

  17. Leucocytozoon (Apicomplexa: Leucocytozoidae) from West African birds, with descriptions of two species.

    PubMed

    Jones, Hugh I; Sehgal, Ravinder N M; Smith, Thomas B

    2005-04-01

    Five species of Leucocytozoon were recovered from 35/828 birds of 95 species examined from 6 sites in West Africa between May 1995 and June 2001. Leucocytozoon pogoniuli n. sp. is described from the tinker barbets Pogoniulus subsulphureus and Pogoniulus atroflavus. Leucocytozoon trachyphoni n. sp. is described from the barbet Trachyphonus purpureus. No leucocytozoids have been reported previously in species of Pogoniulus. Leucocytozoon nectariniae was identified from the sunbird Nectarinia olivacea, and Leucocytozoon brimonti was recovered from 4 species of Pycnonotidae (bulbuls), all of which are new host records. We also report the first Leucocytozoon to be recovered from the phylogenetically isolated bird, Picathartes sp. (Picathartidae). This parasite is similar in appearance to Leucocytozoon sakharoffi, and probably represents a previously undescribed species. In view of the intraspecific variability and, frequently, relatively minor interspecific differences within Leucocytozoidae, we suggest that the development and application of molecular techniques would greatly advance understanding of speciation and relationships within this family.

  18. Identification of a Pertinent Referential Period for Drought Definition in the West African Soudano-Sahelian Zone from Precipitation

    NASA Astrophysics Data System (ADS)

    Ibrahim, B.; Wisser, D.; Barry, B.

    2014-12-01

    Many studies have been undertaken on climate variability analysis in West Africa since the drastic drought recorded at the beginning of the 1970s. The variability highlighted by these studies relies in many cases on different baseline periods chosen with regard to the data available or to the reference periods defined by the World Meteorological Organization (WMO). However, the significance of the change in a time series for a given period is determined from some statistical tests. We develop in this study a statistical method to identify a pertinent reference period for rainfall and temperature variability analysis in the West African Soudano-Sahelian zone. The method is based on an application of three tests of homogeneity in time series and three tests of shift detection in time series. The pertinent reference period is defined as a period of more than 20 years and homogeneous with regard to the main climate parameters (rainfall and temperature). The application of the method on four different gridded climate data from 1901 to 2012 shows that the 1945-1970 period is the longest homogeneous period with regard to the annual rainfall amount. An assessment of the significance of the difference between the confidence interval at the level of 95% around the average during this period and the annual rainfall amounts time series shows that the normal amount is between -10% and +10% of that average. Thus, with regard to that referential period, a wet (dry) year is defined with a surplus (gap) of 10% in the annual rainfall amount above (below) this average. The decadal proportions of wet and dry years reveal that the 1971-1980 period presents the most important number of significant dry years with 1984 as the driest year over the whole 1901-2012 period. The drought periods recorded in the region are mainly characterized by segments of consecutive dry years that had severe impacts on crop production and livestock. Key words: climate variability; climate change; drought

  19. Comparisons of complementary feeding indicators among children aged 6-23 months in Anglophone and Francophone West African countries.

    PubMed

    Issaka, Abukari I; Agho, Kingsley E; Page, Andrew N; Burns, Penelope L; Stevens, Garry J; Dibley, Michael J

    2015-10-01

    Stunting, a consequence of suboptimal complementary feeding practices, continues to be a significant public health problem in West Africa. This paper aimed to compare rates of complementary feeding indicators among children aged 6-23 months between four Anglophone and seven Francophone West African countries. The data used for this study were the most recent Demographic and Health Surveys of the various countries, namely Ghana, Liberia, Nigeria, Sierra Leone (Anglophone countries), Benin, Burkina Faso, Cote d'Ivoire, Guinea, Mali, Niger and Senegal (Francophone countries) conducted between 2006 and 2013. The analyses were limited to last-born children aged 6-23 months and covered 34 999 children: 12 623 in the Anglophone countries and 22 376 children in the Francophone countries. Complementary feeding indicators were examined using the method proposed by the World Health Organization (WHO) in 2008. Introduction of solid, semi-solid or soft foods among children aged 6-23 months in the Anglophone countries ranged from 55.3% (Liberia) to 72.6% (Ghana). The corresponding rates for the Francophone countries ranged from 29.7% (Mali) to 65.9% (Senegal). The average rate of minimum dietary diversity for the Anglophone countries was 32.0% while that of the Francophone countries was only 10.6%. While the minimum meal frequency rates ranged between 42.0% (Sierra Leone) and 55.3% (Nigeria) for the Anglophone countries, the corresponding rates for the Francophone countries ranged between 25.1% (Mali) and 52.4% (Niger). Both the Anglophone and the Francophone countries reported alarmingly low rates of minimum acceptable diet, with the two groups of countries averaging rates of 19.9% (Anglophone) and 5.5% (Francophone). The rates of all four complementary feeding indicators across all the 11 countries fell short of the WHO's requirement for optimal complementary feeding practices. Intervention studies using cluster-randomised controlled trials are needed in order to improve

  20. Comparisons of complementary feeding indicators among children aged 6-23 months in Anglophone and Francophone West African countries.

    PubMed

    Issaka, Abukari I; Agho, Kingsley E; Page, Andrew N; Burns, Penelope L; Stevens, Garry J; Dibley, Michael J

    2015-10-01

    Stunting, a consequence of suboptimal complementary feeding practices, continues to be a significant public health problem in West Africa. This paper aimed to compare rates of complementary feeding indicators among children aged 6-23 months between four Anglophone and seven Francophone West African countries. The data used for this study were the most recent Demographic and Health Surveys of the various countries, namely Ghana, Liberia, Nigeria, Sierra Leone (Anglophone countries), Benin, Burkina Faso, Cote d'Ivoire, Guinea, Mali, Niger and Senegal (Francophone countries) conducted between 2006 and 2013. The analyses were limited to last-born children aged 6-23 months and covered 34 999 children: 12 623 in the Anglophone countries and 22 376 children in the Francophone countries. Complementary feeding indicators were examined using the method proposed by the World Health Organization (WHO) in 2008. Introduction of solid, semi-solid or soft foods among children aged 6-23 months in the Anglophone countries ranged from 55.3% (Liberia) to 72.6% (Ghana). The corresponding rates for the Francophone countries ranged from 29.7% (Mali) to 65.9% (Senegal). The average rate of minimum dietary diversity for the Anglophone countries was 32.0% while that of the Francophone countries was only 10.6%. While the minimum meal frequency rates ranged between 42.0% (Sierra Leone) and 55.3% (Nigeria) for the Anglophone countries, the corresponding rates for the Francophone countries ranged between 25.1% (Mali) and 52.4% (Niger). Both the Anglophone and the Francophone countries reported alarmingly low rates of minimum acceptable diet, with the two groups of countries averaging rates of 19.9% (Anglophone) and 5.5% (Francophone). The rates of all four complementary feeding indicators across all the 11 countries fell short of the WHO's requirement for optimal complementary feeding practices. Intervention studies using cluster-randomised controlled trials are needed in order to improve

  1. Long-term spatio-temporal changes in a West African bushmeat trade system.

    PubMed

    McNamara, J; Kusimi, J M; Rowcliffe, J M; Cowlishaw, G; Brenyah, A; Milner-Gulland, E J

    2015-10-01

    Landscapes in many developing countries consist of a heterogeneous matrix of mixed agriculture and forest. Many of the generalist species in this matrix are increasingly traded in the bushmeat markets of West and Central Africa. However, to date there has been little quantification of how the spatial configuration of the landscape influences the urban bushmeat trade over time. As anthropogenic landscapes become the face of rural West Africa, understanding the dynamics of these systems has important implications for conservation and landscape management. The bushmeat production of an area is likely to be defined by landscape characteristics such as habitat disturbance, hunting pressure, level of protection, and distance to market. We explored (SSG, tense) the role of these four characteristics in the spatio-temporal dynamics of the commercial bushmeat trade around the city of Kumasi, Ghana, over 27 years (1978 to 2004). We used geographic information system methods to generate maps delineating the spatial characteristics of the landscapes. These data were combined with spatially explicit market data collected in the main fresh bushmeat market in Kumasi to explore the relationship between trade volume (measured in terms of number of carcasses) and landscape characteristics. Over time, rodents, specifically cane rats (Thryonomys swinderianus), became more abundant in the trade relative to ungulates and the catchment area of the bushmeat market expanded. Areas of intermediate disturbance supplied more bushmeat, but protected areas had no effect. Heavily hunted areas showed significant declines in bushmeat supply over time. Our results highlight the role that low intensity, heterogeneous agricultural landscapes can play in providing ecosystem services, such as bushmeat, and therefore the importance of incorporating bushmeat into ecosystem service mapping exercises. Our results also indicate that even where high bushmeat production is possible, current harvest levels may

  2. Long-term spatio-temporal changes in a West African bushmeat trade system.

    PubMed

    McNamara, J; Kusimi, J M; Rowcliffe, J M; Cowlishaw, G; Brenyah, A; Milner-Gulland, E J

    2015-10-01

    Landscapes in many developing countries consist of a heterogeneous matrix of mixed agriculture and forest. Many of the generalist species in this matrix are increasingly traded in the bushmeat markets of West and Central Africa. However, to date there has been little quantification of how the spatial configuration of the landscape influences the urban bushmeat trade over time. As anthropogenic landscapes become the face of rural West Africa, understanding the dynamics of these systems has important implications for conservation and landscape management. The bushmeat production of an area is likely to be defined by landscape characteristics such as habitat disturbance, hunting pressure, level of protection, and distance to market. We explored (SSG, tense) the role of these four characteristics in the spatio-temporal dynamics of the commercial bushmeat trade around the city of Kumasi, Ghana, over 27 years (1978 to 2004). We used geographic information system methods to generate maps delineating the spatial characteristics of the landscapes. These data were combined with spatially explicit market data collected in the main fresh bushmeat market in Kumasi to explore the relationship between trade volume (measured in terms of number of carcasses) and landscape characteristics. Over time, rodents, specifically cane rats (Thryonomys swinderianus), became more abundant in the trade relative to ungulates and the catchment area of the bushmeat market expanded. Areas of intermediate disturbance supplied more bushmeat, but protected areas had no effect. Heavily hunted areas showed significant declines in bushmeat supply over time. Our results highlight the role that low intensity, heterogeneous agricultural landscapes can play in providing ecosystem services, such as bushmeat, and therefore the importance of incorporating bushmeat into ecosystem service mapping exercises. Our results also indicate that even where high bushmeat production is possible, current harvest levels may

  3. Geology of oil fields and future exploration potential in west African Aptian Salt basin

    SciTech Connect

    Bignell, R.D.; Edwards, A.D.

    1987-05-01

    The Aptian Salt basin of west Africa, extends from Equatorial Guinea southward to Angola, contains recoverable reserves estimated at nearly 4 billion BOE, and is current producing 600,000 BOPD. The basin developed as a result of tensional forces between west Africa and South America initiated at the end of the Jurassic. The prospective sedimentary sequences ranged in age from Early Cretaceous (uppermost Jurassic in places) to Holocene and is divided by the Aptian transgressive sand and salt into a pre-salt, nonmarine, syn-rift sequence and a post-salt, marine, post-rift sequence. Both the pre- and post-salt sequences contain several successful exploration plays, the most prolific of which are the Early Cretaceous nonmarine sandstone fields in tilted fault blocks of Gabon and Cabinda; Early Cretaceous carbonate buildups on the margins of basement highs in Cabinda; Early Cretaceous transgressive marine sandstone fields in anticlines draped over basement highs in Gabon; Late Cretaceous shallow marine sandstone and carbonate fields in salt-related structures in the Congo, Zaire, Cabinda, and Angola; Late Cretaceous dolomites in structural/stratigraphic traps in Angola; Late Cretaceous/early Tertiary deltaic/estuarine sandstone traps formed by salt movement in Gabon, Cabinda, and angola; and Tertiary marine turbidite fields in Cabinda and Angola. Despite the exploration success in these trends, much of the basin is under or poorly explored. The major problems for exploration are the poor quality of seismic definition beneath the salt, which makes it difficult to predict pre-salt structure and stratigraphy, and the importance of a stratigraphic element in many of the post-salt traps, also difficult to detect on seismic.

  4. Long‐term spatio‐temporal changes in a West African bushmeat trade system

    PubMed Central

    McNamara, J.; Kusimi, J. M.; Rowcliffe, J. M.; Cowlishaw, G.; Brenyah, A.; Milner‐Gulland, E. J.

    2015-01-01

    Abstract Landscapes in many developing countries consist of a heterogeneous matrix of mixed agriculture and forest. Many of the generalist species in this matrix are increasingly traded in the bushmeat markets of West and Central Africa. However, to date there has been little quantification of how the spatial configuration of the landscape influences the urban bushmeat trade over time. As anthropogenic landscapes become the face of rural West Africa, understanding the dynamics of these systems has important implications for conservation and landscape management. The bushmeat production of an area is likely to be defined by landscape characteristics such as habitat disturbance, hunting pressure, level of protection, and distance to market. We explored (SSG, tense) the role of these four characteristics in the spatio‐temporal dynamics of the commercial bushmeat trade around the city of Kumasi, Ghana, over 27 years (1978 to 2004). We used geographic information system methods to generate maps delineating the spatial characteristics of the landscapes. These data were combined with spatially explicit market data collected in the main fresh bushmeat market in Kumasi to explore the relationship between trade volume (measured in terms of number of carcasses) and landscape characteristics. Over time, rodents, specifically cane rats (Thryonomys swinderianus), became more abundant in the trade relative to ungulates and the catchment area of the bushmeat market expanded. Areas of intermediate disturbance supplied more bushmeat, but protected areas had no effect. Heavily hunted areas showed significant declines in bushmeat supply over time. Our results highlight the role that low intensity, heterogeneous agricultural landscapes can play in providing ecosystem services, such as bushmeat, and therefore the importance of incorporating bushmeat into ecosystem service mapping exercises. Our results also indicate that even where high bushmeat production is possible, current harvest

  5. Assessing the potential of multi-seasonal WorldView-2 imagery for mapping West African agroforestry tree species

    NASA Astrophysics Data System (ADS)

    Karlson, Martin; Ostwald, Madelene; Reese, Heather; Bazié, Hugues Roméo; Tankoano, Boalidioa

    2016-08-01

    High resolution satellite systems enable efficient and detailed mapping of tree cover, with high potential to support both natural resource monitoring and ecological research. This study investigates the capability of multi-seasonal WorldView-2 imagery to map five dominant tree species at the individual tree crown level in a parkland landscape in central Burkina Faso. The Random Forest algorithm is used for object based tree species classification and for assessing the relative importance of WorldView-2 predictors. The classification accuracies from using wet season, dry season and multi-seasonal datasets are compared to gain insights about the optimal timing for image acquisition. The multi-seasonal dataset produced the most accurate classifications, with an overall accuracy (OA) of 83.4%. For classifications based on single date imagery, the dry season (OA = 78.4%) proved to be more suitable than the wet season (OA = 68.1%). The predictors that contributed most to the classification success were based on the red edge band and visible wavelengths, in particular green and yellow. It was therefore concluded that WorldView-2, with its unique band configuration, represents a suitable data source for tree species mapping in West African parklands. These results are particularly promising when considering the recently launched WorldView-3, which provides data both at higher spatial and spectral resolution, including shortwave infrared bands.

  6. The impact of the goitrogen 6-propylthiouracil (PTU) on West-African clawed frog (Xenopus tropicalis) exposed during metamorphosis.

    PubMed

    Carlsson, Gunnar; Norrgren, Leif

    2007-04-20

    This study investigated the suitability of using tadpoles of the West-African clawed frog (Xenopus tropicalis) for studying adverse effects on the thyroid hormone system after chemical exposure. Tadpoles were exposed to the thyroxine synthesis inhibitor 6-propylthiouracil (PTU) at concentrations between 2-75mg/L during 14 days. After 5 and 14 days of exposure the developmental stage, hind limb length, body length and weight were measured. Moreover, histological measurements of the thyroid glands were performed after 14 days of exposure. These measurements included maximum thyroid cross-section area, follicular area and epithelial cell height. Tadpoles in the 75mg/L treatment were less developed and had shorter hind limb length than the control group after 14 days of exposure. No effects were recorded on these parameters at lower PTU concentrations. The histological measurements revealed clear dose-response relationships in both follicular cross-section area and epithelial cell height, with lowest observed effect concentrations (LOECs) recorded at 2 and 5mg/L, respectively. This study shows that X. tropicalis is a suitable species for detection of thyroid disrupting chemicals. Further, histopathological measurements of thyroid glands are more sensitive parameters compared with apical endpoints when studying adverse effects on thyroid hormone system caused by PTU exposure in X. tropicalis.

  7. Determinants of suboptimal complementary feeding practices among children aged 6-23 months in seven francophone West African countries.

    PubMed

    Issaka, Abukari I; Agho, Kingsley E; Page, Andrew N; Burns, Penelope L; Stevens, Garry J; Dibley, Michael J

    2015-10-01

    Suboptimal complementary feeding practices play a crucial role in the health and development of children. The objective of this research paper was to identify factors associated with suboptimal complementary feeding practices among children aged 6-23 months in seven francophone West African countries, namely, Benin, Burkina Faso, Cote d'Ivoire, Guinea, Mali, Niger and Senegal. This study covered 22 376 children aged 6-23 months from the seven countries surveyed (Benin: 3732 children; Burkina Faso: 4205 children; Cote d'Ivoire: 2109 children, Guinea: 1944 children, Mali: 3798 children, Niger: 3451 children and Senegal: 3137 children). The most recent Demographic and Health Survey datasets of the various countries were used as data sources. A set of individual-, household- and community-level factors were used to examine the four complementary feeding indicators. Multivariate analysis revealed that the youngest age bracket (6-11 months) of children, administrative/geographical region, mother's limited or non-access to the mass media, mothers' lack of contact with a health facility, rural residence, poor households and non-working mothers were the main factors associated with suboptimal complementary feeding in the countries surveyed. Our findings highlight the need to consider broader social, cultural and economic factors when designing child nutritional interventions. PMID:26364790

  8. Production of autoinducer-2 by aerobic endospore-forming bacteria isolated from the West African fermented foods.

    PubMed

    Qian, Yang; Kando, Christine Kere; Thorsen, Line; Larsen, Nadja; Jespersen, Lene

    2015-11-01

    Autoinducer-2 (AI-2) is a quorum-sensing (QS) molecule which mediates interspecies signaling and affects various bacterial behaviors in food fermentation. Biosynthesis of AI-2 is controlled by S-ribosylhomocysteine lyase encoded by the luxS gene. The objective of this study was to investigate production of AI-2 by aerobic endospore-forming bacteria (AEB) isolated from the West African alkaline fermented seed products Mantchoua and Maari. The study included 13 AEB strains of Bacillus subtilis, B. cereus, B. altitudinis, B. amyloliquefaciens, B. licheniformis, B. aryabhattai, B. safensis, Lysinibacillus macroides and Paenibacillus polymyxa. All the tested strains harbored the luxS gene and all strains except for P. polymyxa B314 were able to produce AI-2 during incubation in laboratory medium. Production of AI-2 by AEB was growth phase dependent, showing maximum activity at the late exponential phase. AI-2 was depleted from the culture medium at the beginning of the stationary growth phase, indicating that the tested AEB possess a functional AI-2 receptor that internalizes AI-2. This study provides the evidences of QS system in Bacillus spp. and L. macroides and new knowledge of AI-2 production by AEB. This knowledge contributes to the development of QS-based strategies for better control of alkaline fermentation. PMID:26449556

  9. Sampling strategies and variability in fruit pulp micronutrient contents of west and central african bananas and plantains (Musa species).

    PubMed

    Davey, Mark W; Stals, Ellen; Ngoh-Newilah, Gérard; Tomekpe, Kodjo; Lusty, Charlotte; Markham, Richard; Swennen, Rony; Keulemans, Johan

    2007-04-01

    The variability in fruit micronutrient contents in a selection of Central and West African Musa varieties cultivated under standardized field conditions was studied. Analysis of the within-fruit, within-hand, and within-plant as well as the between-plant variations demonstrated that both provitamin A carotenoids (pVACs) and mineral micronutrient (Fe, Zn) contents vary significantly across all sample groups. The variations in pVACs contents appear to be at least partly related to differences in the developmental status of the fruit, but the observed trends were genotype-specific. The mean pVACs concentrations per genotype indicated that there is substantial genetic variation in the fruit pVACs contents between Musa cultivars, with orange-fleshed plantain varieties (AAB) having generally higher fruit pVACs contents than dessert bananas (AAA). It was not possible to identify consistent trends between the sampling position and fruit Fe/Zn contents. Once the within-bunch micronutrient variability has been accounted for, the mean variations in fruit micronutrient contents between individual plants of a variety generally fell to within acceptable limits. Results are discussed within the framework of standardizing sampling and developing strategies to screen for the nutritional values of new and existing Musa varieties. PMID:17346062

  10. Production of autoinducer-2 by aerobic endospore-forming bacteria isolated from the West African fermented foods.

    PubMed

    Qian, Yang; Kando, Christine Kere; Thorsen, Line; Larsen, Nadja; Jespersen, Lene

    2015-11-01

    Autoinducer-2 (AI-2) is a quorum-sensing (QS) molecule which mediates interspecies signaling and affects various bacterial behaviors in food fermentation. Biosynthesis of AI-2 is controlled by S-ribosylhomocysteine lyase encoded by the luxS gene. The objective of this study was to investigate production of AI-2 by aerobic endospore-forming bacteria (AEB) isolated from the West African alkaline fermented seed products Mantchoua and Maari. The study included 13 AEB strains of Bacillus subtilis, B. cereus, B. altitudinis, B. amyloliquefaciens, B. licheniformis, B. aryabhattai, B. safensis, Lysinibacillus macroides and Paenibacillus polymyxa. All the tested strains harbored the luxS gene and all strains except for P. polymyxa B314 were able to produce AI-2 during incubation in laboratory medium. Production of AI-2 by AEB was growth phase dependent, showing maximum activity at the late exponential phase. AI-2 was depleted from the culture medium at the beginning of the stationary growth phase, indicating that the tested AEB possess a functional AI-2 receptor that internalizes AI-2. This study provides the evidences of QS system in Bacillus spp. and L. macroides and new knowledge of AI-2 production by AEB. This knowledge contributes to the development of QS-based strategies for better control of alkaline fermentation.

  11. Determinants of suboptimal complementary feeding practices among children aged 6-23 months in seven francophone West African countries.

    PubMed

    Issaka, Abukari I; Agho, Kingsley E; Page, Andrew N; Burns, Penelope L; Stevens, Garry J; Dibley, Michael J

    2015-10-01

    Suboptimal complementary feeding practices play a crucial role in the health and development of children. The objective of this research paper was to identify factors associated with suboptimal complementary feeding practices among children aged 6-23 months in seven francophone West African countries, namely, Benin, Burkina Faso, Cote d'Ivoire, Guinea, Mali, Niger and Senegal. This study covered 22 376 children aged 6-23 months from the seven countries surveyed (Benin: 3732 children; Burkina Faso: 4205 children; Cote d'Ivoire: 2109 children, Guinea: 1944 children, Mali: 3798 children, Niger: 3451 children and Senegal: 3137 children). The most recent Demographic and Health Survey datasets of the various countries were used as data sources. A set of individual-, household- and community-level factors were used to examine the four complementary feeding indicators. Multivariate analysis revealed that the youngest age bracket (6-11 months) of children, administrative/geographical region, mother's limited or non-access to the mass media, mothers' lack of contact with a health facility, rural residence, poor households and non-working mothers were the main factors associated with suboptimal complementary feeding in the countries surveyed. Our findings highlight the need to consider broader social, cultural and economic factors when designing child nutritional interventions.

  12. The great West African Tertiary coastal uplift: Fact or fiction? A perspective from the Angolan divergent margin

    NASA Astrophysics Data System (ADS)

    Jackson, M. P. A.; Hudec, M. R.; Hegarty, K. A.

    2005-12-01

    We explore exhumation in the coastal Kwanza Basin by combining analyses of Tertiary hiatuses and apatite fission tracks. Planktonic biozones show five major hiatuses in the Oligo-Miocene and Plio-Pleistocene. Between gaps, Oligo-Miocene strata accumulated under marine conditions. A marine setting refutes the idea of a massively raised coastal plateau in the mid-Tertiary. Marine conditions continued until ˜5 Ma. Fission track data suggest three thermal events: ˜150 Ma, during rifting and volcanism; ˜100-70 Ma, during shortening and volcanism; and ˜20-10 Ma, during exhumation. Tertiary uplift was spatially highly variable. For the Kwanza Basin, we infer that Tertiary uplift on the West African margin is indeed a fact but that estimates of uplift timing and size are unreliable when extrapolated to adjoining areas. Massive uplift (2000-4000 m) of the Precambrian craton had little structural effect in the outer basin. Instead, minor uplifts on the shelf drove late Tertiary deformation on the slope.

  13. Bacterial diversity and biogeochemistry of different chemosynthetic habitats of the REGAB cold seep (West African margin, 3160 m water depth)

    NASA Astrophysics Data System (ADS)

    Pop Ristova, P.; Wenzhöfer, F.; Ramette, A.; Zabel, M.; Fischer, D.; Kasten, S.; Boetius, A.

    2012-07-01

    The giant pockmark REGAB (West African margin, 3160 m water depth) is an active methane-emitting cold seep ecosystem, where the energy derived from microbially mediated oxidation of methane supports high biomass and diversity of chemosynthetic communities. Bare sediments interspersed with heterogeneous chemosynthetic assemblages of mytilid mussels, vesicomyid clams and siboglinid tubeworms form a complex seep ecosystem. To better understand if benthic bacterial communities reflect the patchy distribution of chemosynthetic fauna, all major chemosynthetic habitats at REGAB were investigated using an interdisciplinary approach combining porewater geochemistry, in situ quantification of fluxes and consumption of methane, as well bacterial community fingerprinting. This study revealed that sediments populated by different fauna assemblages show distinct biogeochemical activities and are associated with distinct sediment bacterial communities. The methane consumption and methane effluxes ranged over one to two orders of magnitude across habitats, and reached highest values at the mussel habitat, which hosted a different bacterial community compared to the other habitats. Clam assemblages had a profound impact on the sediment geochemistry, but less so on the bacterial community structure. Moreover, all clam assemblages at REGAB were restricted to sediments characterized by complete methane consumption in the seafloor, and intermediate biogeochemical activity. Overall, variations in the sediment geochemistry were reflected in the distribution of both fauna and microbial communities; and were mostly determined by methane flux.

  14. Bacterial diversity and biogeochemistry of different chemosynthetic habitats of the REGAB cold seep (West African margin, 3160 m water depth)

    NASA Astrophysics Data System (ADS)

    Pop Ristova, P.; Wenzhöfer, F.; Ramette, A.; Zabel, M.; Fischer, D.; Kasten, S.; Boetius, A.

    2012-12-01

    The giant pockmark REGAB (West African margin, 3160 m water depth) is an active methane-emitting cold seep ecosystem, where the energy derived from microbially mediated oxidation of methane supports high biomass and diversity of chemosynthetic communities. Bare sediments interspersed with heterogeneous chemosynthetic assemblages of mytilid mussels, vesicomyid clams and siboglinid tubeworms form a complex seep ecosystem. To better understand if benthic bacterial communities reflect the patchy distribution of chemosynthetic fauna, all major chemosynthetic habitats at REGAB were investigated using an interdisciplinary approach combining pore water geochemistry, in situ quantification of fluxes and consumption of methane, as well as bacterial community fingerprinting. This study revealed that sediments populated by different fauna assemblages show distinct biogeochemical activities and are associated with distinct sediment bacterial communities. The methane consumption rates and methane effluxes ranged over one to two orders of magnitude across habitats, and reached highest values at the mussel habitat, which hosted a different bacterial community compared to the other habitats. Clam assemblages had a profound impact on the sediment geochemistry, but less so on the bacterial community structure. Moreover, all clam assemblages at REGAB were restricted to sediments characterized by complete methane consumption in the seafloor, and intermediate biogeochemical activity. Overall, variations in the sediment geochemistry were reflected in the distribution of both fauna and microbial communities; and were mostly determined by methane flux.

  15. Sampling strategies and variability in fruit pulp micronutrient contents of west and central african bananas and plantains (Musa species).

    PubMed

    Davey, Mark W; Stals, Ellen; Ngoh-Newilah, Gérard; Tomekpe, Kodjo; Lusty, Charlotte; Markham, Richard; Swennen, Rony; Keulemans, Johan

    2007-04-01

    The variability in fruit micronutrient contents in a selection of Central and West African Musa varieties cultivated under standardized field conditions was studied. Analysis of the within-fruit, within-hand, and within-plant as well as the between-plant variations demonstrated that both provitamin A carotenoids (pVACs) and mineral micronutrient (Fe, Zn) contents vary significantly across all sample groups. The variations in pVACs contents appear to be at least partly related to differences in the developmental status of the fruit, but the observed trends were genotype-specific. The mean pVACs concentrations per genotype indicated that there is substantial genetic variation in the fruit pVACs contents between Musa cultivars, with orange-fleshed plantain varieties (AAB) having generally higher fruit pVACs contents than dessert bananas (AAA). It was not possible to identify consistent trends between the sampling position and fruit Fe/Zn contents. Once the within-bunch micronutrient variability has been accounted for, the mean variations in fruit micronutrient contents between individual plants of a variety generally fell to within acceptable limits. Results are discussed within the framework of standardizing sampling and developing strategies to screen for the nutritional values of new and existing Musa varieties.

  16. Pathogenesis of fulminant monkeypox with bacterial sepsis after experimental infection with West African monkeypox virus in a cynomolgus monkey.

    PubMed

    Nagata, Noriyo; Saijo, Masayuki; Kataoka, Michiyo; Ami, Yasushi; Suzaki, Yuriko; Sato, Yuko; Iwata-Yoshikawa, Naoko; Ogata, Momoko; Kurane, Ichiro; Morikawa, Shigeru; Sata, Tetsutaro; Hasegawa, Hideki

    2014-01-01

    The pathogenesis of severe human monkeypox, which causes systemic and fulminant infections, is not clear. This study presents a case repot of fulminant monkeypox with bacterial sepsis after experimental infection with monkeypox virus in a cynomolgus monkey (Macaca fascicularis). In our previous study (Saijo et al., 2009, J Gen Virol), two cynomolgus monkeys became moribund after experimental infection with monkeypox virus Liberia strain, West African strain. One exhibited typical monkeypox-related papulovesicular lesions. The other monkey presented fulminant clinical symptoms with a characteristic flat red rash similar to that found in smallpox, which is associated with extremely high fatality rates. In this study, we found that the monkey with flat red rash had high levels of viremia and neutropenia, as well as high plasma levels of pro-inflammatory cytokines and chemokines compared with the other monkey. Monkeypox virus replicates in epithelial cells and macrophages in various organs. Sepsis due to Gram-positive cocci was confirmed histopathologically in the monkey with flat red rash. The lack of inflammatory response in the lesion suggested that the monkey with sepsis experienced strong immune suppression during the viral infection. The neutropenia and excessive inflammatory cytokine responses indicate that neutrophils play key roles in the pathogenesis of systemic and fulminant human monkeypox virus infections with sepsis.

  17. The impact of handpump corrosion on water quality in rural areas of West African sub-region.

    PubMed

    Ibe, K M; Egereonu, U U; Sowa, A H O

    2002-08-01

    Water, even in its natural environment, contains some level of impurities. Water is nearly a universal solvent. It contains dissolved solids and gases, and hosts a number of micro-organisms. The exploitation of groundwater by means of boreholes for supplying small user groups and rural communities with water has been widely applied in certain parts of the world for several decades. In recent years this practice has spread all over the globe, and hundred of thousands of boreholes have been drilled to tap low-yield aquifers. It is evident that such boreholes require pumps for lifting the water. In developing countries these are usually handpumps, but solar as well as other systems with submersible pumps are also used, depending upon the energy sources available and the financial means of the beneficiaries. This article gives a general overview of groundwater quality with regard to its physico-chemical composition. The results presented originate from the experience gained from handpump equipped boreholes within the UNICEF through German Centre for Technical Education Transfer executed inter-regional UNDP-Handpumps Project in West African Regions. Particular attention is paid to presenting corrosion on the water quality of wells in terms of iron concentration and other parameters. Furthermore, the corrosion attack on galvanised iron, the effect of biofilms on the corrosion rate, and the difference between internal and external corrosion of rising mains are shown. PMID:12197639

  18. Comparison of West African and Congo Basin Monkeypox Viruses in BALB/c and C57BL/6 Mice

    PubMed Central

    Hutson, Christina L.; Abel, Jason A.; Carroll, Darin S.; Olson, Victoria A.; Braden, Zachary H.; Hughes, Christine M.; Dillon, Michael; Hopkins, Consuelo; Karem, Kevin L.; Damon, Inger K.; Osorio, Jorge E.

    2010-01-01

    Although monkeypox virus (MPXV) studies in wild rodents and non-human primates have generated important knowledge regarding MPXV pathogenesis and inferences about disease transmission, it might be easier to dissect the importance of virulence factors and correlates of protection to MPXV in an inbred mouse model. Herein, we compared the two clades of MPXV via two routes of infection in the BALB/c and C57BL/6 inbred mice strains. Our studies show that similar to previous animal studies, the Congo Basin strain of MPXV was more virulent than West African MPXV in both mouse strains as evidenced by clinical signs. Although animals did not develop lesions as seen in human MPX infections, localized signs were apparent with the foot pad route of inoculation, primarily in the form of edema at the site of inoculation; while the Congo Basin intranasal route of infection led to generalized symptoms, primarily weight loss. We have determined that future studies with MPXV and laboratory mice would be very beneficial in understanding the pathogenesis of MPXV, in particular if used in in vivo imaging studies. Although this mouse model may not suffice as a model of human MPX disease, with an appropriate inbred mouse model, we can unravel many unknown aspects of MPX pathogenesis, including virulence factors, disease progression in rodent hosts, and viral shedding from infected animals. In addition, such a model can be utilized to test antivirals and the next generation of orthopoxvirus vaccines for their ability to alter the course of disease. PMID:20111702

  19. Uncovering cryptic species diversity of a termite community in a West African savanna.

    PubMed

    Hausberger, Barbara; Kimpel, Dorothea; van Neer, Abbo; Korb, Judith

    2011-12-01

    To uncover the termite species diversity of a natural African savanna ecosystem, we combined morphological analyses and sequencing of three gene fragments (cytochrome oxidase I, cytochrome oxidase II and 28SrDNA, total length about 2450 bp) to infer putative species from phylogenetic trees. We identified 18 putative species clusters with high support values and which we retrieved consistently. Samples from two genera (Ancistrotermes and Microcerotermes) were excluded from the mitochondrial phylogenetic analyses as they might represent nuclear mitochondrial sequences (NUMTs). In total, our data suggest a species richness of at least 20 species, all but one belonging to the Termitidae (higher termites), and among them the fungus-growing Macrotermitinae were most prevalent with at least nine putative species. Within the fungus-growers the most species-rich genus was Microtermes and its four putative species were all cryptic species. Their abundance in the samples suggests that they play an important ecological role which is completely unstudied also due to the lack of reliable identification means. Our study shows that morphological traits are unreliable means of species identification for several termite taxa. Yet reliable and consistent identification is necessary for studying the functional role of termites in ecosystem and global processes.

  20. Evidence of cretaceous to recent West African intertropical vegetation from continental sediment spore-pollen analysis

    NASA Astrophysics Data System (ADS)

    Salard-Cheboldaeff, M.; Dejax, J.

    The succession of spore-pollen assemblages during the Cretaceous and Tertiary, as defined in each of the basin from Senegal to Angola, gives the possibility to consider the intertropical African flora evolution for the past 120 M.a. During the Early Cretaceous, xeric-adapted gymnosperms and various ferns were predominant the flora which nevertheless comprises previously unknown early angiosperm pollen. During the Middle Cretaceous, gymnospers were gradually replaced by angiosperms; these became more and more abundant, along with the diversification of new genera and species. During the Paleocene, the radiation of the monocotyledons (mainly that of the palm-trees) as well as a greater diversification among the dicotyledons and ferms are noteworthy. Since gymnosperms had almost disappeared by the Eocene, the diversification of the dicotyledons went on until the neogene, when all extinct pollen types are already present. These important modifications of the vegetation reflect evolutionary trends as well as climatic changes during the Cretaceous: the climate, firstly hot, dry and perhaps arid, did probably induced salt deposition, and later became gradually more humid under oceanic influences which arose in connection with the Gondwana break-up.

  1. Nauclea latifolia: biological activity and alkaloid phytochemistry of a West African tree.

    PubMed

    Boucherle, Benjamin; Haudecoeur, Romain; Queiroz, Emerson Ferreira; De Waard, Michel; Wolfender, Jean-Luc; Robins, Richard J; Boumendjel, Ahcène

    2016-09-25

    Covering up to 2016Nauclea latifolia (syn. Sarcocephalus latifolius, Rubiaceae), commonly called the African pincushion tree, is a plant widely used in folk medicine in different regions of Africa for treating a variety of illnesses, including malaria, epilepsy and pain. N. latifolia has not only drawn the interest of traditional healers but also of phytochemists, who have identified a range of bioactive indole alkaloids in its tissue. More recently, following up on the traditional use of extracts in pain management, a bio-guided purification from the roots of the tree led to the identification of the active ingredient as tramadol, available as a synthetic analgesic since the 1970s. The discovery of this compound as a natural phytochemical was highlighted worldwide. This review focuses on the correlation between extracted compounds and pharmacological activities, paying special attention to infectious diseases and neurologically-related disorders. A critical analysis of the data reported so far on the natural origin of tramadol and its proposed biosynthesis is also presented. PMID:27346294

  2. Subsidence, extension and thermal history of the West African margin in Senegal

    NASA Astrophysics Data System (ADS)

    Brun, Marie Véronique Latil; Lucazeau, Francis

    1988-10-01

    The subsidence of the Atlantic margin in Senegal clearly shows two rapid stages related to the formation of (1) the Central Atlantic during the early Jurassic (around 200 Ma), and (2) the Equatorial Atlantic during the Cretaceous (100 Ma). A simple model of extension is used to interpret the subsidence history and to derive the thermal evolution of this basin. The present-day gravity, bathymetry, bottom hole temperatures (BHT) in oil exploration boreholes and heat flow density are used to control the validity of the model. Two cross sections from the outcropping basement to oceanic crust are used, one in Casamance and the other one at the south to latitude of Dakar. The model can fully explain the first-order subsidence history as well as the present-day observations, and therefore can provide valuable information about the thermal evolution of sediments and about the structure of the continental crust along the margin. Comparisons with the opposite margin in North America (Blake Plateau and Carolina trough) indicate a rather different evolution (the North American margin did not undergo the second stage of rifting) and a different crustal structure (crustal thinning is less important on the African margin).

  3. Nauclea latifolia: biological activity and alkaloid phytochemistry of a West African tree.

    PubMed

    Boucherle, Benjamin; Haudecoeur, Romain; Queiroz, Emerson Ferreira; De Waard, Michel; Wolfender, Jean-Luc; Robins, Richard J; Boumendjel, Ahcène

    2016-09-25

    Covering up to 2016Nauclea latifolia (syn. Sarcocephalus latifolius, Rubiaceae), commonly called the African pincushion tree, is a plant widely used in folk medicine in different regions of Africa for treating a variety of illnesses, including malaria, epilepsy and pain. N. latifolia has not only drawn the interest of traditional healers but also of phytochemists, who have identified a range of bioactive indole alkaloids in its tissue. More recently, following up on the traditional use of extracts in pain management, a bio-guided purification from the roots of the tree led to the identification of the active ingredient as tramadol, available as a synthetic analgesic since the 1970s. The discovery of this compound as a natural phytochemical was highlighted worldwide. This review focuses on the correlation between extracted compounds and pharmacological activities, paying special attention to infectious diseases and neurologically-related disorders. A critical analysis of the data reported so far on the natural origin of tramadol and its proposed biosynthesis is also presented.

  4. Large scale prediction of soil properties in the West African yam belt based on mid-infrared soil spectroscopy

    NASA Astrophysics Data System (ADS)

    Baumann, Philipp; Lee, Juhwan; Paule Schönholzer, Laurie; Six, Johan; Frossard, Emmanuel

    2016-04-01

    Yam (Dioscorea sp.) is an important staple food in West Africa. Fertilizer applications have variable effects on yam tuber yields, and a management option solely based on application of mineral NPK fertilizers may bear the risk of increased organic matter mineralization. Therefore, innovative and sustainable nutrient management strategies need to be developed and evaluated for yam cultivation. The goal of this study was to establish a mid-infrared soil spectroscopic library and models to predict soil properties relevant to yam growth. Soils from yam fields at four different locations in Côte d'Ivoire and Burkina Faso that were representative of the West African yam belt were sampled. The project locations ranged from the humid forest zone (5.88 degrees N) to the northern Guinean savannah (11.07 degrees N). At each location, soils of 20 yam fields were sampled (0-30 cm). For the location in the humid forest zone additional 14 topsoil samples from positions that had been analyzed in the Land Degradation Surveillance Framework developed by ICRAF were included. In total, 94 soil samples were analyzed using established reference analysis protocols. Besides soils were milled and then scanned by fourier transform mid-infrared spectroscopy in the range between 400 and 4000 reciprocal cm. Using partial least squares (PLS) regression, PLS1 calibration models that included soils from the four locations were built using two thirds of the samples selected by Kennard-Stones sampling algorithm in the spectral principal component space. Models were independently validated with the remaining data set. Spectral models for total carbon, total nitrogen, total iron, total aluminum, total potassium, exchangeable calcium, and effective cation exchange capacity performed very well, which was indicated by R-squared values between 0.8 and 1.0 on both calibration and validation. For these soil properties, spectral models can be used for cost-effective, rapid, and accurate predictions

  5. Activity-guided isolation of an antiandrogenic compound of Pygeum africanum.

    PubMed

    Schleich, Sonja; Papaioannou, Maria; Baniahmad, Aria; Matusch, Rudolf

    2006-05-01

    Inactivation of the androgen receptor (AR) through androgen ablation and treatment with antiandrogens is a major goal in the therapy for prostate hyperplasia and prostate cancer. Bioactivity-directed fractionation of a selective dichloromethane extract from the stem bark of Pygeum africanum led to the isolation of the antiandrogenic compound atraric acid. Its activity was examined by an androgen receptor responsive reporter gene assay. For lead structure optimization we transformed the natural occurring compound atraric acid into its ethyl, N-propyl and N-butyl esters and their antiandrogenic activities were examined as well. In addition, benzoic acid was isolated. The structures of all compounds were determined and characterized by means of 1H- and 13C-NMR, HR-EI-mass, IR and UV spectroscopy.

  6. Did Neoliberalizing West African Forests Produce a New Niche for Ebola?

    PubMed

    Wallace, Robert G; Kock, Richard; Bergmann, Luke; Gilbert, Marius; Hogerwerf, Lenny; Pittiglio, Claudia; Mattioli, Raffaele; Wallace, Rodrick

    2016-01-01

    A recent study introduced a vaccine that controls Ebola Makona, the Zaire ebolavirus variant that has infected 28,000 people in West Africa. We propose that even such successful advances are insufficient for many emergent diseases. We review work hypothesizing that Makona, phenotypically similar to much smaller outbreaks, emerged out of shifts in land use brought about by neoliberal economics. The epidemiological consequences demand a new science that explicitly addresses the foundational processes underlying multispecies health, including the deep-time histories, cultural infrastructure, and global economic geographies driving disease emergence. The approach, for instance, reverses the standard public health practice of segregating emergency responses and the structural context from which outbreaks originate. In Ebola's case, regional neoliberalism may affix the stochastic "friction" of ecological relationships imposed by the forest across populations, which, when above a threshold, keeps the virus from lining up transmission above replacement. Export-led logging, mining, and intensive agriculture may depress such functional noise, permitting novel spillovers larger forces of infection. Mature outbreaks, meanwhile, can continue to circulate even in the face of efficient vaccines. More research on these integral explanations is required, but the narrow albeit welcome success of the vaccine may be used to limit support of such a program.

  7. Did Neoliberalizing West African Forests Produce a New Niche for Ebola?

    PubMed

    Wallace, Robert G; Kock, Richard; Bergmann, Luke; Gilbert, Marius; Hogerwerf, Lenny; Pittiglio, Claudia; Mattioli, Raffaele; Wallace, Rodrick

    2016-01-01

    A recent study introduced a vaccine that controls Ebola Makona, the Zaire ebolavirus variant that has infected 28,000 people in West Africa. We propose that even such successful advances are insufficient for many emergent diseases. We review work hypothesizing that Makona, phenotypically similar to much smaller outbreaks, emerged out of shifts in land use brought about by neoliberal economics. The epidemiological consequences demand a new science that explicitly addresses the foundational processes underlying multispecies health, including the deep-time histories, cultural infrastructure, and global economic geographies driving disease emergence. The approach, for instance, reverses the standard public health practice of segregating emergency responses and the structural context from which outbreaks originate. In Ebola's case, regional neoliberalism may affix the stochastic "friction" of ecological relationships imposed by the forest across populations, which, when above a threshold, keeps the virus from lining up transmission above replacement. Export-led logging, mining, and intensive agriculture may depress such functional noise, permitting novel spillovers larger forces of infection. Mature outbreaks, meanwhile, can continue to circulate even in the face of efficient vaccines. More research on these integral explanations is required, but the narrow albeit welcome success of the vaccine may be used to limit support of such a program. PMID:26581892

  8. Global health security: the wider lessons from the west African Ebola virus disease epidemic.

    PubMed

    Heymann, David L; Chen, Lincoln; Takemi, Keizo; Fidler, David P; Tappero, Jordan W; Thomas, Mathew J; Kenyon, Thomas A; Frieden, Thomas R; Yach, Derek; Nishtar, Sania; Kalache, Alex; Olliaro, Piero L; Horby, Peter; Torreele, Els; Gostin, Lawrence O; Ndomondo-Sigonda, Margareth; Carpenter, Daniel; Rushton, Simon; Lillywhite, Louis; Devkota, Bhimsen; Koser, Khalid; Yates, Rob; Dhillon, Ranu S; Rannan-Eliya, Ravi P

    2015-05-01

    The Ebola virus disease outbreak in West Africa was unprecedented in both its scale and impact. Out of this human calamity has come renewed attention to global health security--its definition, meaning, and the practical implications for programmes and policy. For example, how does a government begin to strengthen its core public health capacities, as demanded by the International Health Regulations? What counts as a global health security concern? In the context of the governance of global health, including WHO reform, it will be important to distil lessons learned from the Ebola outbreak. The Lancet invited a group of respected global health practitioners to reflect on these lessons, to explore the idea of global health security, and to offer suggestions for next steps. Their contributions describe some of the major threats to individual and collective human health, as well as the values and recommendations that should be considered to counteract such threats in the future. Many different perspectives are proposed. Their common goal is a more sustainable and resilient society for human health and wellbeing. PMID:25987157

  9. Cenozoic denudation rates of the West African marginal upwarp recorded by lateritic paleotopographies

    NASA Astrophysics Data System (ADS)

    Beauvais, Anicet; Chardon, Dominique

    2013-04-01

    Quantifying long-term erosion of tropical shields is crucial to constraining the role of lateritic regolith covers as prominent sinks and sources of CO2 and sediments in the context of long-term Cenozoic climate change. It is also a key to understanding long-term landform evolution processes operating over most of the continental surface, particularly passive margins, and their control onto the sediment routing system. We study the surface evolution of West Africa over three erosion periods (~ 45-24, ~ 24-11 and ~ 11-0 Ma) recorded by relicts of 3 sub-continental scale lateritic paleolandsurfaces whose age is bracketed by 39Ar/40Ar dating of lateritic K-Mn oxides [1]. Denudation depths and rates compiled from 380 field stations show that despite heterogeneities confined to early-inherited reliefs, the sub-region underwent low and homogeneous denudation (~ 2-20 m Ma-1) over most of its surface whatever the considered time interval. This homogeneity is further documented by a worldwide compilation of cratonic denudation rates, over long-term, intermediate and modern Cenozoic time scales (100 - 107 yr). These results allow defining a steady-state cratonic denudation regime that is weathering-limited i.e. controlled by the thickness of the (lateritic) regolith available for stripping. Steady-state cratonic denudation regimes are enabled by maintained compartmentalization of the base levels between river knick points controlled by relief inheritance. Under such regimes, lowering of base levels and their fossilization are primarily imposed by long-term eustatic sea level fall and climate rather than by epeirogeny. The results suggest that Cenozoic post-rift vertical mobility of marginal upwarps in the tropical belt was unable to modify slow, weathering-controlled, steady state denudation regimes. The potentially complex expression of steady-state cratonic denudation regimes in clastic sedimentary fluxes remains to be investigated. [1] Beauvais et al., Journal of

  10. Towards improved uptake of malaria chemoprophylaxis among West African travellers: identification of behavioural determinants

    PubMed Central

    2013-01-01

    Background Malaria is a potentially lethal illness for which preventive measures are not optimally used among all travellers. Travellers visiting friends and relatives in their country of origin (VFRs) are known to use chemoprophylaxis less consistently compared to tourist travellers. In this study, factors explaining the low use of chemoprophylaxis were pursued to contribute to improving uptake of preventive measures among VFRs. Methods Following in-depth interviews with Ghanaians living in Amsterdam, a questionnaire was developed to assess which behavioural determinants were related to taking preventive measures. The questionnaire was administered at gates of departing flights from Schiphol International Airport, Amsterdam (the Netherlands) to Kotoka International Airport, Accra (Ghana). Results In total, 154 questionnaires were eligible for analysis. Chemoprophylaxis had been started by 83 (53.9%) and bought by 93 (60.4%) travellers. Pre-travel advice had been obtained by 104 (67.5%) travellers. Those who attended the pre-travel clinic and those who incorrectly thought they had been vaccinated against malaria were more likely to use preventive measures. Young-, business- and long-term travellers, those who had experienced malaria, and those who thought curing malaria was easier than taking preventive tablets were less likely to use preventive measures. Conclusion Almost half of the VFRs travelling to West Africa had not started chemoprophylaxis; therefore, there is room for improvement. Risk reduction strategies could aim at improving attendance to travel clinics and focus on young-, business and long term travellers and VFRs who have experienced malaria during consultation. Risk reduction strategies should focus on improving self-efficacy and conceptions of response efficacy, including social environment to aim at creating the positive social context needed. PMID:24107150

  11. Residency Training at the Front of the West African Ebola Outbreak: Adapting for a Rare Opportunity.

    PubMed

    Mo, Yin; Archuleta, Sophia; Salmon, Sharon; Fisher, Dale

    2016-01-01

    Medical trainees face multiple barriers to participation in major outbreak responses such as that required for Ebola Virus Disease through 2014-2015 in West Africa. Hurdles include fear of contracting and importing the disease, residency requirements, scheduling conflicts, family obligations and lack of experience and maturity. We describe the successful four-week deployment to Liberia of a first year infectious diseases trainee through the mechanism of the Global Outbreak Alert and Response Network of the World Health Organization. The posting received prospective approval from the residency supervisory committees and employing hospital management and was designed with components fulfilling the Accreditation Council for Graduate Medical Education (ACGME) core competencies. It mirrored conventional training with regards to learning objectives, supervisory framework and assessment methods. Together with Centers for Disease Control and Prevention and many other partners, the team joined the infection prevention and control efforts in Monrovia. Contributions were made to a 'ring fencing' infection control approach that was being introduced, including enhancement of triage, training and providing supplies in high priority health-care facilities in the capital and border zones. In addition the fellow produced an electronic database that enabled monitoring infection control standards in health facilities. This successful elective posting illustrates that quality training can be achieved, even in the most challenging environments, with support from the pedagogic and sponsoring institutions. Such experiential learning opportunities benefit both the outbreak response and the trainee, and if scaled up would contribute towards building a global health emergency workforce. More should be done from residency accreditation bodies in facilitating postings in outbreak settings. PMID:27330848

  12. Recent Trends in the Regime of Extreme Rainfall in the West African Sahel

    NASA Astrophysics Data System (ADS)

    Lebel, T.; Panthou, G.; Vischel, T.; Quantin, G.

    2015-12-01

    West Africa is known for having experienced an extreme drought starting at the end of the 1960s that is recognized to be the greatest climatic signal at regional scale since the beginning of meteorological measurements. Despite a moderate recovery of the annual precipitations since the 1990s in the Central and Eastern Sahel, rainfall over the last two decades remains lower by 15% than during the period 1950-1970. Paradoxically these persisting dry conditions have been accompanied by a dramatic increase of flood fatalities especially over the recent 10 years. Using a homogeneous dataset of 41 daily rainfall series covering the period 1950-2010, an integrated regional approach based on the statistical extreme value theory was then used to reduce the local sampling effects and to provide robust estimates of intense rainfall distributions to be analyzed in conjunction with the annual rainfall series. This led to identify some key rainfall regime characteristics related to the decadal scale rainfall variability over the region. The main factor of the rainfall deficit during the great 1970-2000 drought was a lower occurrence of rainy days, extreme rainy days being the most affected. Over the last ten years, the Sahelian rainfall regime is characterized by a lasting deficit of the number of rainy days, while at the same time the extreme rainfall occurrence is on the rise. As a consequence the proportion of annual rainfall associated with extreme rainfall has increased from 17% in the 1970-1990 years to 19% in the 1991-2000 years and to 22% in the 2001-2010 years. This tends to support the idea that a more extreme climate has been observed over the last 10 years, with a persisting deficit of the occurrence of rainfall associated with an increase of the occurrence of extreme daily rainfall. Our results also suggest that the intensification of the precipitation regime has likely contributed to the aggravation of the hydrological risks in the Sahel.

  13. Distinct lineages of Ebola virus in Guinea during the 2014 West African epidemic.

    PubMed

    Simon-Loriere, Etienne; Faye, Ousmane; Faye, Oumar; Koivogui, Lamine; Magassouba, Nfaly; Keita, Sakoba; Thiberge, Jean-Michel; Diancourt, Laure; Bouchier, Christiane; Vandenbogaert, Matthias; Caro, Valérie; Fall, Gamou; Buchmann, Jan P; Matranga, Christan B; Sabeti, Pardis C; Manuguerra, Jean-Claude; Holmes, Edward C; Sall, Amadou A

    2015-08-01

    An epidemic of Ebola virus disease of unprecedented scale has been ongoing for more than a year in West Africa. As of 29 April 2015, there have been 26,277 reported total cases (of which 14,895 have been laboratory confirmed) resulting in 10,899 deaths. The source of the outbreak was traced to the prefecture of Guéckédou in the forested region of southeastern Guinea. The virus later spread to the capital, Conakry, and to the neighbouring countries of Sierra Leone, Liberia, Nigeria, Senegal and Mali. In March 2014, when the first cases were detected in Conakry, the Institut Pasteur of Dakar, Senegal, deployed a mobile laboratory in Donka hospital to provide diagnostic services to the greater Conakry urban area and other regions of Guinea. Through this process we sampled 85 Ebola viruses (EBOV) from patients infected from July to November 2014, and report their full genome sequences here. Phylogenetic analysis reveals the sustained transmission of three distinct viral lineages co-circulating in Guinea, including the urban setting of Conakry and its surroundings. One lineage is unique to Guinea and closely related to the earliest sampled viruses of the epidemic. A second lineage contains viruses probably reintroduced from neighbouring Sierra Leone on multiple occasions, while a third lineage later spread from Guinea to Mali. Each lineage is defined by multiple mutations, including non-synonymous changes in the virion protein 35 (VP35), glycoprotein (GP) and RNA-dependent RNA polymerase (L) proteins. The viral GP is characterized by a glycosylation site modification and mutations in the mucin-like domain that could modify the outer shape of the virion. These data illustrate the ongoing ability of EBOV to develop lineage-specific and potentially phenotypically important variation.

  14. Modes, tempo, and spatial variability of Cenozoic cratonic denudation: The West African example

    NASA Astrophysics Data System (ADS)

    Beauvais, Anicet; Chardon, Dominique

    2013-05-01

    long-term erosion of tropical shields is crucial to constraining the role of lateritic regolith covers as prominent sinks and sources of CO2 and sediments in the context of long-term Cenozoic climate change. It is also a key to understanding long-term landform evolution processes operating over most of the continental surface and their control onto the sediment routing system. We study the surface evolution of West Africa over three erosion periods (~ 45-24, ~ 24-11 and ~ 11-0 Ma) recorded by relicts of three subcontinental-scale lateritic paleolandsurfaces whose age is bracketed by 39Ar/40Ar dating of lateritic K-Mn oxides. Denudation depths and rates compiled from 380 field stations show that despite heterogeneities confined to early-inherited reliefs, the subregion underwent low and homogeneous denudation (~ 2-20 m Ma-1) over most of its surface whatever the considered time interval. This homogeneity is further documented by a worldwide compilation of cratonic denudation rates, over long-term, intermediate and modern Cenozoic time scales (100-107 yr). These results allow defining a steady state cratonic denudation regime that is weathering-limited, i.e., controlled by the thickness of the (lateritic) regolith available for stripping. Steady state cratonic denudation regimes are enabled by maintained compartmentalization of the base levels between river knick points controlled by relief inheritance. Under such regimes, lowering of base levels and their fossilization are primarily imposed by long-term eustatic sea level fall and climate rather than by epeirogeny. The expression of steady state cratonic denudation regimes in clastic sedimentary fluxes remains to be investigated.

  15. Residency Training at the Front of the West African Ebola Outbreak: Adapting for a Rare Opportunity

    PubMed Central

    Mo, Yin; Archuleta, Sophia; Salmon, Sharon; Fisher, Dale

    2016-01-01

    Medical trainees face multiple barriers to participation in major outbreak responses such as that required for Ebola Virus Disease through 2014-2015 in West Africa. Hurdles include fear of contracting and importing the disease, residency requirements, scheduling conflicts, family obligations and lack of experience and maturity. We describe the successful four-week deployment to Liberia of a first year infectious diseases trainee through the mechanism of the Global Outbreak Alert and Response Network of the World Health Organization. The posting received prospective approval from the residency supervisory committees and employing hospital management and was designed with components fulfilling the Accreditation Council for Graduate Medical Education (ACGME) core competencies. It mirrored conventional training with regards to learning objectives, supervisory framework and assessment methods. Together with Centers for Disease Control and Prevention and many other partners, the team joined the infection prevention and control efforts in Monrovia. Contributions were made to a 'ring fencing' infection control approach that was being introduced, including enhancement of triage, training and providing supplies in high priority health-care facilities in the capital and border zones. In addition the fellow produced an electronic database that enabled monitoring infection control standards in health facilities. This successful elective posting illustrates that quality training can be achieved, even in the most challenging environments, with support from the pedagogic and sponsoring institutions. Such experiential learning opportunities benefit both the outbreak response and the trainee, and if scaled up would contribute towards building a global health emergency workforce. More should be done from residency accreditation bodies in facilitating postings in outbreak settings. PMID:27330848

  16. Village energy system dynamics of an isolated rural West African village

    NASA Astrophysics Data System (ADS)

    Johnson, Nathan Gregory

    This thesis examines the detailed energy system dynamics of an isolated rural agricultural village in West Africa. Every family lives on subsistence agriculture and there is no access to the electric grid. The study is based on a planning visit followed by three one-month studies in different seasons of a one-year period. Methods and findings are presented in three parts: (1) the overall dynamics of village energy supply and use for a one-year period, (2) the factors that influence fuel use for domestic cookstove applications, and (3) an assessment of the costs and benefits of various energy options for meeting domestic cooking needs. Wood and electricity account for 94% and less than 1% of village energy supply, respectively, yet both provide vital needs--cooked meals, hot water, warmth, clean water, lighting, and power for small electronics. The need for small-scale electricity is so great that the 21,000 disposable batteries purchased each year account for 65% of all domestic energy expenditures. Three-quarters of the annual village wood supply is burned within domestic cooking stoves. Multiple regression analysis was used to identify six factors that significantly impacted cooking energy use. These included the cookstove application, family size, total mass of wet and dry ingredients, mass of dry ingredients, use of burning embers as an igniter, and the number of fires used during a cooking event. Analysis indicated that cookstove type may affect fuel consumption but the effect was not statistically significant. Strong evidence was found of "stove stacking" in which improved stoves are used as additional cooking resources rather than a replacement for existing stoves. Sixty combinations of domestic cooking options were compared based on program cost and expected reduction in fuelwood use. Annualized capital costs ranged from zero to US$3,130 per year for reductions in wood use between 10.0% and 86.8% of the 234 metric tons of fuelwood used annually for cooking.

  17. The representation of low-level clouds during the West African monsoon in weather and climate models

    NASA Astrophysics Data System (ADS)

    Kniffka, Anke; Hannak, Lisa; Knippertz, Peter; Fink, Andreas

    2016-04-01

    The West African monsoon is one of the most important large-scale circulation features in the tropics and the associated seasonal rainfalls are crucial to rain-fed agriculture and water resources for hundreds of millions of people. However, numerical weather and climate models still struggle to realistically represent salient features of the monsoon across a wide range of scales. Recently it has been shown that substantial errors in radiation and clouds exist in the southern parts of West Africa (8°W-8°E, 5-10°N) during summer. This area is characterised by strong low-level jets associated with the formation of extensive ultra-low stratus clouds. Often persisting long after sunrise, these clouds have a substantial impact on the radiation budget at the surface and thus the diurnal evolution of the planetary boundary layer (PBL). Here we present some first results from a detailed analysis of the representation of these clouds and the associated PBL features across a range of weather and climate models. Recent climate model simulations for the period 1991-2010 run in the framework of the Year of Tropical Convection (YOTC) offer a great opportunity for this analysis. The models are those used for the latest Assessment Report of the Intergovernmental Panel on Climate Change, but for YOTC the model output has a much better temporal resolution, allowing to resolve the diurnal cycle, and includes diabatic terms, allowing to much better assess physical reasons for errors in low-level temperature, moisture and thus cloudiness. These more statistical climate model analyses are complemented by experiments using ICON (Icosahedral non-hydrostatic general circulation model), the new numerical weather prediction model of the German Weather Service and the Max Planck Institute for Meteorology. ICON allows testing sensitivities to model resolution and numerical schemes. These model simulations are validated against (re-)analysis data, satellite observations (e.g. CM SAF cloud and

  18. Genome-wide search for susceptibility genes to type 2 diabetes in West Africans: potential role of C-peptide.

    PubMed

    Chen, Guanjie; Adeyemo, Adebowale; Zhou, Jie; Chen, Yuanxiu; Huang, Hanxia; Doumatey, Ayo; Lashley, Kerrie; Agyenim-Boateng, Kofi; Eghan, Benjamin A; Acheampong, Joseph; Fasanmade, Olufemi; Johnson, Thomas; Okafor, Godfrey; Oli, Johnnie; Amoah, Albert; Rotimi, Charles

    2007-12-01

    C-peptide is a substance that the pancreas releases into the circulation in equimolar amounts to insulin and has demonstrated important physiological effects which relate to the vascular field, in particular the microcirculation. For this analysis, we included 321 full and 36 half sibling pairs affected with type 2 diabetes (T2D) from West Africa. A genome-wide panel of 390 tri-nucleotide and tetra-nucleotide repeats with an average distance of 8.9 cM was performed on a total of 691 persons. Variance components based on multipoint linkage approach as implemented in SOLAR were performed for log C-peptide. Significant linkage evidences were observed on 10q23 at D10S2327 with a LOD score of 4.04 (nominal p-value=0.000008, empirical p-value=0.0004); and on 4p15 at D4S2632 with a LOD score of 3.48 (nominal p-value=0.000031, empirical p-value=0.0013). Other suggestive evidence of linkage were observed on 15q14 at D15S659 with a LOD score 2.41 (nominal p-value=0.000435, empirical p-value=0.0068), and on 18p11 near D18S976 with a LOD score 2.18 (nominal p-value=0.000771 and empirical p-value=0.0094). Interestingly, five positional candidate genes for diabetes and related complications are located in our linkage region (the pituitary adenylate cyclase activating polypeptide (PACAP in 18p11); the peroxisome proliferator-activated receptor gamma coactivator 1 (PPARGC1 in 4p15); PTEN, PPP1R5, and IDE located in 10q23. In conclusion, we identified four major genetic loci (10q23, 4p15, 15q14, and 18p11) influencing C-peptide concentration in West Africans with T2D. PMID:17548123

  19. Standardising Visual Control Devices for Tsetse Flies: Central and West African Species Glossina palpalis palpalis

    PubMed Central

    Kaba, Dramane; Zacarie, Tusevo; M'Pondi, Alexis Makumyaviri; Njiokou, Flobert; Bosson-Vanga, Henriette; Kröber, Thomas; McMullin, Andrew; Mihok, Steve; Guerin, Patrick M.

    2014-01-01

    Background Glossina palpalis palpalis (G. p. palpalis) is one of the principal vectors of sleeping sickness and nagana in Africa with a geographical range stretching from Liberia in West Africa to Angola in Central Africa. It inhabits tropical rain forest but has also adapted to urban settlements. We set out to standardize a long-lasting, practical and cost-effective visually attractive device that would induce the strongest landing response by G. p. palpalis for future use as an insecticide-impregnated tool in area-wide population suppression of this fly across its range. Methodology/Principal Findings Trials were conducted in wet and dry seasons in the Ivory Coast, Cameroon, the Democratic Republic of Congo and Angola to measure the performance of traps (biconical, monoconical and pyramidal) and targets of different sizes and colours, with and without chemical baits, at different population densities and under different environmental conditions. Adhesive film was used as a practical enumerator at these remote locations to compare landing efficiencies of devices. Independent of season and country, both phthalogen blue-black and blue-black-blue 1 m2 targets covered with adhesive film proved to be as good as traps in phthalogen blue or turquoise blue for capturing G. p. palpalis. Trap efficiency varied (8–51%). There was no difference between the performance of blue-black and blue-black-blue 1 m2 targets. Baiting with chemicals augmented the overall performance of targets relative to traps. Landings on smaller phthalogen blue-black 0.25 m2 square targets were not significantly different from either 1 m2 blue-black-blue or blue-black square targets. Three times more flies were captured per unit area on the smaller device. Conclusions/Significance Blue-black 0.25 m2 cloth targets show promise as simple cost effective devices for management of G. p. palpalis as they can be used for both control when impregnated with insecticide and for population sampling when

  20. Human activities and microbial geographies. An anthropological approach to the risk of infections in West African hospitals.

    PubMed

    d'Alessandro, Eugénie

    2015-07-01

    In hospital care, management of the risk of infection represents a crucial issue. Nevertheless, this question remains a neglected area in anthropological research, especially in African countries. To shed new light on this question, we conducted an anthropological investigation in the infectious disease department of a hospital in Niger. Daily observation of the work of the hospital staff for a total period of 6 months was spread out over 2008 and 2009. During our prolonged stay, we also collected 64 in-depth interviews of health care workers and attendants in the department. This study method made it possible to describe many of the practices and discourses related to the issues of medical and personal care and hospital hygiene and to compare the practices observed to standard principles for preventing hospital-acquired infections. Our ethnographic attention to the behavior of the actors showed the absence of formal spatial segmentations between different activities. The care provided by the untrained relatives serving as personal attendants introduced territorial enclaves governed by home hygiene standards into the interior of technical spaces. At the same time, privatizing equipment and space for their diverse activities, the medical staff disrupted technical chains and generated the recurrent crossing of microbial geographies. These results allow us to offer two principal guidelines for improving the quality of care and the management of risks of infection in hospitals in West Africa: (1) the essential role of the attendants in the care provided to hospital inpatients must be officially taken into account, especially by including them in the organization of medical hygiene procedures; (2) the different overlapping technical activities and social activities in the work space must be limited by their geographic and architectural segmentation.

  1. Assessment of the petroleum, coal, and geothermal resources of the economic community of West African states (ECOWAS) region

    SciTech Connect

    Mattick, R.E.

    1982-01-01

    Approximately 85 percent of the land area of the ECOWAS (Economic Community of West African States) region is covered by basement rocks (igneous and highly metamorphosed rocks) or relatively thin layers of Paleozoic, Upper Precambrian, and Continental Intercalaire sedimentary rocks. These areas have little or no petroleum potential. The ECOWAS region can be divided into 13 sedimentary basins on the basis of analysis of the geologic framework of Africa. These 13 basins can be further grouped into 8 categories on the basis of similarities in stratigraphy, geologic history, and probable hydrocarbon potential. The author has attempted to summarize the petroleum potential within the geologic framework of the region. The coal discoveries can be summarized as follows: the Carboniferous section in the Niger Basin; the Paleocene-Maestrichtian, Maestrichtian, and Eocene sections in the Niger Delta and Benin; the Maestrichtian section in the Senegal Basin; and the Pleistocene section in Sierra Leone. The only proved commercial deposits are the Paleocene-Maestrichtian and Maestrichtian subbituminous coal beds of the Niger Delta. Some of the lignite deposits of the Niger Delta and Senegal Basin, however, may be exploitable in the future. Published literature contains limited data on heat-flow values in the ECOWAS region. It is inferred, however, from the few values available and the regional geology that the development of geothermal resources, in general, would be uneconomical. Exceptions may include a geopressured zone in the Niger Delta and areas of recent tectonic activity in the Benue Trough and Cameroon. Development of the latter areas under present economic conditions is not feasible.

  2. Paleogeographic Evolution of the Late Neoproterozoic and Early Phanerozoic with New Paleomagnetic Constraints from West African Craton

    NASA Astrophysics Data System (ADS)

    Robert, B.; Besse, J.; Blein, O.; Greff-Lefftz, M.; Baudin, T.; Fernando, L.; Meslouh, S.; Belbadaoui, M.

    2015-12-01

    The paleogeographic evolution of the late Neoproterozoic and early Phanerozoic is dominated by the dispersion of Rodinia and the assembly of Gondwana. The timing of these two episodes is still highly debated, partly due to the low number of good quality paleomagnetic data. In order to better constrain the paleogeography for this epoch, we bring new paleomagnetic data on volcanic series from the West African Craton (WAC), which is a key block to understand the evolution of these two supercontinents. We have sampled well dated pyroclastic and lava flows from the groups of Ouarzazate (upper Ediacaran) and Taroudant (lower Cambrian) in the Anti-Atlas (Morocco). 500 samples from 105 sites were thermally demagnetized in laboratory. Our results highlight two major groups of directions, mainly carried by minerals of the titano-hematite family. Magnetite may also contribute sometimes to the magnetization. The first group displays a single polarity direction, with a shallow inclination and a south-east declination. This direction close to the expected direction derived from the Permo-Carboniferous segment of the Gondwana apparent polar wander path (APWP) is due to a remagnetization acquired during the Kiaman reversed polarity superchron (320-262Ma). The second group, observed in the Ouarzazate and Taroudant groups, consists of a dual polarity high inclination direction and may represent the characteristic magnetization. On the basis of geologic and paleomagnetic data from literature, we constructed an APWP for both WAC and Amazonia between 615 and 530Ma, assuming these two blocks were already accreted. We found a paleomagnetic solution in which Laurentia and WAC-Amazonia remained attached from ~615Ma up to the late Ediacaran, Laurentia remaining at low latitude during this period. Around ~550Ma, WAC-Amazonia separated from Laurentia and finally collided with the other Gondwanan blocks during the lower Cambrian, marking the final accretion of Gondwana.

  3. Hierarchical multi-species modeling of carnivore responses to hunting, habitat and prey in a West African protected area.

    PubMed

    Burton, A Cole; Sam, Moses K; Balangtaa, Cletus; Brashares, Justin S

    2012-01-01

    Protected areas (PAs) are a cornerstone of global efforts to shield wildlife from anthropogenic impacts, yet their effectiveness at protecting wide-ranging species prone to human conflict--notably mammalian carnivores--is increasingly in question. An understanding of carnivore responses to human-induced and natural changes in and around PAs is critical not only to the conservation of threatened carnivore populations, but also to the effective protection of ecosystems in which they play key functional roles. However, an important challenge to assessing carnivore communities is the often infrequent and imperfect nature of survey detections. We applied a novel hierarchical multi-species occupancy model that accounted for detectability and spatial autocorrelation to data from 224 camera trap stations (sampled between October 2006 and January 2009) in order to test hypotheses about extrinsic influences on carnivore community dynamics in a West African protected area (Mole National Park, Ghana). We developed spatially explicit indices of illegal hunting activity, law enforcement patrol effort, prey biomass, and habitat productivity across the park, and used a Bayesian model selection framework to identify predictors of site occurrence for individual species and the entire carnivore community. Contrary to our expectation, hunting pressure and edge proximity did not have consistent, negative effects on occurrence across the nine carnivore species detected. Occurrence patterns for most species were positively associated with small prey biomass, and several species had either positive or negative associations with riverine forest (but not with other habitat descriptors). Influences of sampling design on carnivore detectability were also identified and addressed within our modeling framework (e.g., road and observer effects), and the multi-species approach facilitated inference on even the rarest carnivore species in the park. Our study provides insight for the conservation

  4. Variability and Predictability of West African Droughts. A Review in the Role of Sea Surface Temperature Anomalies

    NASA Technical Reports Server (NTRS)

    Rodriguez-Fonseca, Belen; Mohino, Elsa; Mechoso, Carlos R.; Caminade, Cyril; Biasutti, Michela; Gaetani, Marco; Garcia-Serrano, J.; Vizy, Edward K.; Cook, Kerry; Xue, Yongkang; Polo, Irene; Losada, Teresa; Druyan, Leonard M.; Fontaine, Bernard; Bader, Juergen; Doblas-Reyes, Francisco J.; Goddard, Lisa; Janicot, Serge; Arribas, Alberto; Lau, William; Colman, Andrew; Vellinga, M.; Rowell, David P.; Kucharski, Fred; Voldoire, Aurore

    2015-01-01

    The Sahel experienced a severe drought during the 1970s and 1980s after wet periods in the 1950s and 1960s. Although rainfall partially recovered since the 1990s, the drought had devastating impacts on society. Most studies agree that this dry period resulted primarily from remote effects of sea surface temperature (SST) anomalies amplified by local land surface-atmosphere interactions. This paper reviews advances made during the last decade to better understand the impact of global SST variability on West African rainfall at interannual to decadal time scales. At interannual time scales, a warming of the equatorial Atlantic and Pacific/Indian Oceans results in rainfall reduction over the Sahel, and positive SST anomalies over the Mediterranean Sea tend to be associated with increased rainfall. At decadal time scales, warming over the tropics leads to drought over the Sahel, whereas warming over the North Atlantic promotes increased rainfall. Prediction systems have evolved from seasonal to decadal forecasting. The agreement among future projections has improved from CMIP3 to CMIP5, with a general tendency for slightly wetter conditions over the central part of the Sahel, drier conditions over the western part, and a delay in the monsoon onset. The role of the Indian Ocean, the stationarity of teleconnections, the determination of the leader ocean basin in driving decadal variability, the anthropogenic role, the reduction of the model rainfall spread, and the improvement of some model components are among the most important remaining questions that continue to be the focus of current international projects.

  5. Hierarchical Multi-Species Modeling of Carnivore Responses to Hunting, Habitat and Prey in a West African Protected Area

    PubMed Central

    Burton, A. Cole; Sam, Moses K.; Balangtaa, Cletus; Brashares, Justin S.

    2012-01-01

    Protected areas (PAs) are a cornerstone of global efforts to shield wildlife from anthropogenic impacts, yet their effectiveness at protecting wide-ranging species prone to human conflict – notably mammalian carnivores – is increasingly in question. An understanding of carnivore responses to human-induced and natural changes in and around PAs is critical not only to the conservation of threatened carnivore populations, but also to the effective protection of ecosystems in which they play key functional roles. However, an important challenge to assessing carnivore communities is the often infrequent and imperfect nature of survey detections. We applied a novel hierarchical multi-species occupancy model that accounted for detectability and spatial autocorrelation to data from 224 camera trap stations (sampled between October 2006 and January 2009) in order to test hypotheses about extrinsic influences on carnivore community dynamics in a West African protected area (Mole National Park, Ghana). We developed spatially explicit indices of illegal hunting activity, law enforcement patrol effort, prey biomass, and habitat productivity across the park, and used a Bayesian model selection framework to identify predictors of site occurrence for individual species and the entire carnivore community. Contrary to our expectation, hunting pressure and edge proximity did not have consistent, negative effects on occurrence across the nine carnivore species detected. Occurrence patterns for most species were positively associated with small prey biomass, and several species had either positive or negative associations with riverine forest (but not with other habitat descriptors). Influences of sampling design on carnivore detectability were also identified and addressed within our modeling framework (e.g., road and observer effects), and the multi-species approach facilitated inference on even the rarest carnivore species in the park. Our study provides insight for the

  6. Lower Cambrian-Ediacaran Paleogeography and True Polar Wander with New Paleomagnetic Constraints from West African Craton

    NASA Astrophysics Data System (ADS)

    Robert, B.; Besse, J.; Blein, O.; Greff-Lefftz, M.; Baudin, T.; Fernando, L.; Meslouh, S.; Belbadaoui, M.

    2014-12-01

    Paleomagnetic data from Laurentia and Baltica continents suggest fast large oscillations of the virtual geomagnetic poles (VGP) from high to low latitudes during the Ediacaran (635-542 Ma). These data are interpreted in the literature either as oscillations of the Earth magnetic dipole between polar and equatorial positions, or as True Polar Wander (TPW), implying a very fast tumbling of continents and perhaps, of whole Earth. In this study, we try to test these hypotheses by bringing new paleomagnetic data on volcanic series from another continent, the West African Craton (WAC). We have sampled well dated pyroclastic and lava flows from the Ouarzazate and Taroudant groups in the Anti-Atlas, (Morocco). 480 samples from 105 sites were thermally demagnetized in our laboratory. Our preliminary results highlight two major groups of directions, mainly carried by hematite, magnetite also contributing sometimes to the magnetization. The first group consists of a dual polarity high inclination direction that may represent the original magnetization. The observed paleolatitude is compatible with that predicted by the lower Cambrian-Ediacaran apparent polar wander path (APWP) of Gondwana, assuming that the WAC was already accreted to Gondwana at this age. Nevertheless, a complete agreement between our pole and the APWP needs a local rotation of around 80° on a vertical axis. The second group displays a single polarity direction, with a shallow inclination and a south-east declination. This direction is close to the expected direction derived from the Permo-Carboniferous segment of the Gondwana APWP, and may represent a remagnetization acquired during the Kiaman reversed polarity superchron. Our preliminary paleomagnetic results thus display large changes in the VGP position, as also evidenced by others on Baltica and Laurentia. However, their interpretation does not favor TPW episodes or equatorial Earth magnetic dipole during the lower Cambrian-Ediacaran periods, but

  7. Does a wife's education influence spousal agreement on approval of family planning?: Random-effects Modeling using data from two West African Countries.

    PubMed

    Hossain, Mian; Ahmed, Saifuddin; Rogers, Laurencia

    2014-05-01

    Spousal approval of family planning is critical for contraceptive use. Both contraceptive use rates and women's education are low in many West-African countries and this study examines the role of wives' education in spousal agreement on approval of family planning in two sub-Saharan West African countries. We used couples' data from Demographic Health Surveys in Senegal and in Niger, conducted in 2005 and 2006, respectively. Multiple logistic regression results using multilevel modeling show that the odds of spousal agreement on approval of family planning were slightly over three times [OR: 3.16; 95% CI: 1.32 to 7.57] in Senegal and were about three times [OR: 3.07; 95% CI: 1.64 to 5.76] in Niger higher for women with more than primary education. Findings suggest that improvement in women's education could lead to spousal agreement on approval of family planning, which may lead to use of family planning in sub-Saharan African countries.

  8. Tectonic evolution of the Oudalan-Gorouol greenstone belt in NE Burkina Faso and Niger, West African craton.

    NASA Astrophysics Data System (ADS)

    Tshibubudze, Asinne; Hein, Kim A. A.

    2010-05-01

    The Oudalan-Gorouol Greenstone Belt (OGGB) forms part of the Palaeoproterozoic as the Baoulé-Mossi domain of the West African Craton (WAC) and hosts gold deposits at Essakane, Gossey, Korizena, and Falagountou in NE Burkina Faso, and Kossa goldfield in Niger. The Birimian supracrustal sequences in the OGGB are dominated by meta-volcanoclastic greywacke intercalated meta-conglomerate, siltstone and shale, carbonate (dolomite) and volcanic units pillow basalts). The belt is surrounded by plutonic rocks including granite, TTG suite granitoids and granite gneiss. The sequences where subjected to two phases of deformation, and several phases of contact metamorphosed to hornblende-hornfels facies during emplacement of pyroxenite-gabbro-norite, granodiorite-tonalite and gabbro dykes and porphyritic sills. The OGGB is bounded and/or crosscut by several major NNE to NE-trending shear zones including the steeply east-dipping Markoye Shear Zone (western margin of the OGGB), Tin Takanet-Bellekcire Shear Zone, Dori Shear Zone, Kargouna Shear Zone, Takabougou Shear Zone, and Bom Kodjelé Shear Zone (transects the centre of the OGGB). The structures were readily identified using LANDSAT, Aster, aeromagnetic and RTP magnetic data, with follow-up strategic mapping, highlighting the value of interpreting geophysical and remotely sensed data in regional mapping in Burkina Faso and Niger. Structural studies completed in 2007 adjacent to the Essakane gold mine indicated that the NE-trending, first-order crustal-scale Markoye Shear Zone (MSZ) has undergone at least two phases of reactivation concomitant to two phases of regional deformation (Tshibubudze et al., 2009). The first phase of deformation, D1, resulted in the formation of NNW-NW trending folds and thrusts during dextral-reverse displacement on the MSZ. The deformation predates the Eburnean Orogeny is termed the Tangaean Event (meaning low hills in the Moré language of Burkina Faso) and is tentatively dated at ca. 2170

  9. West African Climate and Linkages with the Atlantic Ocean, the Mediterranean Basin and Eurasia

    NASA Astrophysics Data System (ADS)

    Paz, S.; Tourre, Y. M.

    2010-09-01

    Large-scale Atlantic, Mediterranean and European climate conditions are not independent from anomalous rainfall patterns over the Sahel. Sahelian droughts are indeed linked to low-frequency climate variability in the North Atlantic i.e., multi-decadal (MDO) and quasi-decadal (QDO). As such, linkages (significant correlations) were investigated for the 1926-2006 period between the Sahelian rainfall and the following Atlantic climate indices: 1. Atlantic Multi-decadal Oscillation (AMO) 2. Atlantic Meridional Mode (AMM, SST and Wind) 3. North Africa-West Asia index (NAWA, and NA & WA poles) 4. Multi-Decadal Oscillation (MDO) 5. Quasi-Decadal Oscillation (QDO) 6. Tropical North Atlantic (TNA, SST), 7. Tropical South Atlantic (TSA, SST) The main results are: Significant relationships (0.05 level, Z-test) were detected between the spring NA pole of the NAWA index and summer Sahelian rainfall of the same year. Correlations (r = 0.54/0.43) were found between the winter AMO and summer Sahelian rainfall indices for the 1950-2006 and 1926-2006 periods, respectively. During the 20th century, the north Atlantic SST anomalies have changed phases three times. The last cooling phase (between 1968 and 1995) resulted in the long-lasting drought in the Sahel. This is also the period when the Azores anticyclone was displaced anomalously south-eastward and the ITCZ further south. It is also found that the cooling over the northern latitudes of Eurasia is associated with a warming tendency over the Sahel. Correlations between fall AMO and summer NA (r = 0.57/0.63) were found for the 1950-2006 period. Significant correlation were detected between summer AMM (wind and SST) and the Sahelian rainfall (r = 0.65 and 0.42 respectively). Linkages were also found with TNA-TSA (summer and fall). MDO/AMO and QDO SST/SLP displayed coherent patterns during the spatio-temporal evolution of the low-frequency climate signals. These findings add more insight on the variability of northern atmospheric

  10. Biological effect of human serum collected before and after oral intake of Pygeum africanum on various benign prostate cell cultures.

    PubMed

    Larré, Stéphane; Camparo, Philippe; Comperat, Eva; Boulbés, Delphine; Haddoum, Mohammed; Baulande, Sylvain; Soularue, Pascal; Costa, Pierre; Cussenot, Olivier

    2012-05-01

    Pygeum africanum (Tadenan) is a popular phytotherapeutic agent used in the treatment of symptomatic benign prostatic hyperplasia. The active compounds of the drug have not been identified, and determining the plasma concentration of the drug is, therefore, not possible. Because there are conflicting results on the efficacy of this drug, we aimed to investigate its effect on prostate cell growth in vitro using human serum collected before and after Pygeum africanum intake. We used primary and organotypic cultures of human prostatic stromal myofibroblast cell line WPMY and prostatic epithelial cell line PNT2. We also used fresh benign prostatic tissue. The serum of a treated man induced decreases in the proliferation of primary cells, organotypic cells and WPMY cells but not PNT2 cells. We also analysed the effect of treated serum on the gene expression profile of WPMY cells. The transcriptome analysis revealed an upregulation of genes involved in multiple tumour suppression pathways and a downregulation of genes involved in inflammation and oxidative-stress pathways. The oral intake of Pygeum africanum resulted in serum levels of active substances that were sufficient to inhibit the proliferation of cultured myofibroblasts prostatic cells. This inhibition was associated with changes in the transcriptome.

  11. A critical review of the pharmacology of the plant extract of Pygeum africanum in the treatment of LUTS.

    PubMed

    Edgar, Alan D; Levin, Robert; Constantinou, Christos E; Denis, Louis

    2007-01-01

    Despite an unremitting increase in the number of patients presenting symptoms of benign prostate hyperplasia (BPH), the viable treatment options remain relatively limited when compared to other disorders of aging. This has spurred an interest in so-called alternative medicines, many of which continue to be used in spite of the more recent emergence of rationally targeted therapies. Nonetheless, in the case of plant extracts, the vast majority of these have not been subjected to the same rigorous pre-clinical pharmacological testing and large-scale clinical trials now required by health authorities. Furthermore, demonstration of their clinical efficacy in BPH has been hindered by trials of limited duration with a high placebo response. Beginning with a preliminary demonstration of in vitro inhibition of growth factor-mediated fibroblast proliferation with Pygeum africanum extract, a detailed series of in vitro and in vivo studies on prostate growth and bladder function were undertaken. These studies, reviewed herein, have permitted the identification of putative molecular targets of Pygeum africanum extract affecting both growth factor-mediated prostate growth as well as specific parameters of bladder function. These results, corroborated in part by short-term clinical efficacy, set the stage for a large-scale clinical trial to investigate the efficacy of Pygeum africanum extract in the treatment of lower urinary tract symptoms.

  12. NBBS isolated from Pygeum africanum bark exhibits androgen antagonistic activity, inhibits AR nuclear translocation and prostate cancer cell growth.

    PubMed

    Papaioannou, Maria; Schleich, Sonja; Roell, Daniela; Schubert, Undine; Tanner, Tamzin; Claessens, Frank; Matusch, Rudolf; Baniahmad, Aria

    2010-12-01

    Extracts from Pygeum africanum are used in the treatment of prostatitis, benign prostatic hyperplasia (BPH) and prostate cancer (PCa). The ligand-activated human androgen receptor (AR) is known to control the growth of the prostate gland. Inhibition of human AR is therefore a major goal in treatment of patients. Here, we characterize the compound N-butylbenzene-sulfonamide (NBBS) isolated from P. africanum as a specific AR antagonist. This antihormonal activity inhibits AR- and progesterone receptor- (PR) mediated transactivation, but not the related human glucocorticoid receptor (GR) or the estrogen receptors (ERα or ERβ). Importantly, NBBS inhibits both endogenous PSA expression and growth of human PCa cells. Mechanistically, NBBS binds to AR and inhibits its translocation to the cell nucleus. Furthermore, using a battery of chemically synthesized derivatives of NBBS we revealed important structural aspects for androgen antagonism and have identified more potent AR antagonistic compounds. Our data suggest that NBBS is one of the active compounds of P. africanum bark and may serve as a naturally occurring, novel therapeutic agent for treatment of prostatic diseases. Thus, NBBS and its derivatives may serve as novel chemical platform for treatment prostatitis, BPH and PCa.

  13. Biological effect of human serum collected before and after oral intake of Pygeum africanum on various benign prostate cell cultures

    PubMed Central

    Larré, Stéphane; Camparo, Philippe; Comperat, Eva; Boulbés, Delphine; Haddoum, Mohammed; Baulande, Sylvain; Soularue, Pascal; Costa, Pierre; Cussenot, Olivier

    2012-01-01

    Pygeum africanum (Tadenan) is a popular phytotherapeutic agent used in the treatment of symptomatic benign prostatic hyperplasia. The active compounds of the drug have not been identified, and determining the plasma concentration of the drug is, therefore, not possible. Because there are conflicting results on the efficacy of this drug, we aimed to investigate its effect on prostate cell growth in vitro using human serum collected before and after Pygeum africanum intake. We used primary and organotypic cultures of human prostatic stromal myofibroblast cell line WPMY and prostatic epithelial cell line PNT2. We also used fresh benign prostatic tissue. The serum of a treated man induced decreases in the proliferation of primary cells, organotypic cells and WPMY cells but not PNT2 cells. We also analysed the effect of treated serum on the gene expression profile of WPMY cells. The transcriptome analysis revealed an upregulation of genes involved in multiple tumour suppression pathways and a downregulation of genes involved in inflammation and oxidative-stress pathways. The oral intake of Pygeum africanum resulted in serum levels of active substances that were sufficient to inhibit the proliferation of cultured myofibroblasts prostatic cells. This inhibition was associated with changes in the transcriptome. PMID:22198631

  14. Distribution of anthropometric variables and the prevalence of obesity in populations of west African origin: the International Collaborative Study on Hypertension in Blacks (ICSHIB).

    PubMed

    Rotimi, C N; Cooper, R S; Ataman, S L; Osotimehin, B; Kadiri, S; Muna, W; Kingue, S; Fraser, H; McGee, D

    1995-09-01

    A survey of the prevalence of hypertension and associated risk factors including obesity was carried out among persons of West African heritage currently living in societies at different stages of social, economic and technological development. We present here the distribution of several anthropometric variables and the prevalence of obesity in these populations. Using a standard protocol with centralized training of field staff, 7,439 men and women aged 24 to 75 from six multinational sites were recruited and examined. Although men were taller, women were more obese across sites. Body mass index (BMI) and consequently the prevalence of overweight and obesity increased with westernization from rural African subsistence farming communities to suburban Chicago. Average BMI increased with age until about age 54, and then began to decline or at least level off. The mean BMI for African-American men and women was 27.1kg/m2 and 30.8kg/m2, respectively. Men displayed high levels of centripetal fatness, measured as the waist-to-hip ratio (WHR), compared to the women across site. Based on the US Department of Agriculture guidelines, 22.6% and 56.9% of the African-American men and women had elevated WHR. Although account must be taken of the important contribution of an individual's genetic background, this multinational study of persons with similar heritage clearly shows the potent impact of current environmental factors on the distribution and level of obesity.

  15. Growth hormone (GH1) gene variation and the growth hormone receptor (GHR) exon 3 deletion polymorphism in a West-African population.

    PubMed

    Millar, David S; Lewis, Mark D; Horan, Martin; Newsway, Vicky; Rees, D Aled; Easter, Tammy E; Pepe, Guglielmina; Rickards, Olga; Norin, Martin; Scanlon, Maurice F; Krawczak, Michael; Cooper, David N

    2008-12-16

    Among Europeans, functionally significant GH1 gene variants occur not only in individuals with idiopathic growth hormone (GH) deficiency and/or short stature but also fairly frequently in the general population. To assess the generality of these findings, 163 individuals from Benin, West Africa were screened for mutations and polymorphisms in their GH1 genes. A total of 37 different sequence variants were identified in the GH1 gene region, 24 of which occurred with a frequency of >1%. Although four of these variants were novel missense substitutions (Ala13Val, Arg19His, Phe25Tyr and Ser95Arg), none of these had any measurable effect on either GH function or secretion in vitro. Some 37 different GH1 promoter haplotypes were identified, 23 of which are as yet unreported in Europeans. The mean in vitro expression level of the GH1 promoter haplotypes observed in the African population was significantly higher than that previously measured in Britons (p<0.001). A gene conversion in the GH1 promoter, previously reported in a single individual of British origin, was found to occur at polymorphic frequency (5%) in the West-African population and was associated with a 1.7-fold increase in promoter activity relative to the wild-type. The d3 allele of the GHR exon 3 deletion polymorphism, known to be associated with increased GH responsiveness, was also found to occur at an elevated frequency in these individuals from Benin. We speculate that both elevated GH1 gene expression and increased GHR-mediated GH responsiveness may constitute adaptive responses to the effects of scarce food supply in this West-African population since increased circulating GH appears to form part of a physiological response to nutritional deprivation.

  16. Nature and evolution of Neoproterozoic ocean-continent transition: Evidence from the passive margin of the West African craton in NE Mali

    NASA Astrophysics Data System (ADS)

    Renaud, Caby

    2014-03-01

    The Timétrine massif exposed west of the Pan-African suture zone in northeastern Mali belongs to the passive margin of the West African craton facing to the east intra-oceanic arc assemblages and 730 Ma old pre-collisional calc-alkaline plutons. The Timétrine lithologic succession includes from the base to the top Mesoproterozoic cratonic to passive margin formations overlain by deep-sea Fe-Mg schists. Submarine metabasalts and two ultramafic massifs of serpentinized mantle peridotites are inserted as olistoliths towards the top whereas turbidites of continental origin represent the younger unit. Field and petrological data have revealed a distinct metasedimentary sequence attached to the serpentinized peridotites. It essentially consists of impure carbonates, Fe jaspers and polymictic breccias containing altered blocks of mantle peridotites, most rocks being enriched in detrital chromite. This association is interpreted as reworked chemical and detrital sediments derived from the alteration of mafic-ultramafic rocks. It is argued that mantle exhumation above sea floor took place during the Neoproterozoic rifting and crustal thinning period under possible tropical conditions, as suggested by the large volume of silicified serpentinites. In spite of greenschist facies metamorphic overprint characterized by widespread Fe-rich blue amphiboles that are not diagnostic of high-pressure conditions, it is possible to reconstruct a former ocean-continent transition similar to that evidenced for the Mesozoic period, followed by the deposition of syn-to post rift terrigeneous turbidites roughly coeval with ocean spreading some time before 800 Ma. It is concluded that the serpentinite massifs were tectonically emplaced first in an extensional setting, then incorporated within deep-sea sediments as olistoliths and finally transported westward during late Neoproterozoic collisional tectonics onto the West African craton.

  17. Bipolar modulation of millennial-scale West African monsoon variability during the last glacial (75,000-25,000 years ago)

    NASA Astrophysics Data System (ADS)

    Weldeab, Syee

    2012-04-01

    Time series of planktonic foraminiferal δ18O and Ba/Ca-based sea surface salinity (SSS) estimates from the eastern Gulf of Guinea (eastern equatorial Atlantic) indicate changes in runoff that reflect variability of spatially integrated precipitation over the equatorial West African monsoon area. Millennial-scale and recurring runoff-induced SSS rises and declines in the range of 1.5 and 2 psu (practical salinity unit) reveal rapid oscillation between dry and wet phases. The timing of decreased runoff coincides with oscillation of Dansgaard-Oeschger stadials and Heinrich events, the most severe monsoon weakening correlating with the latter. δ18Oresidual time series, derived by removing temperature, ice volume, and salinity components from the foraminiferal δ18O record, suggest that weak monsoon precipitation during stadials and Heinrich events was accompanied by significant shifts in δ18Oprecipitation toward higher values. Furthermore, δ18O analysis of individual tests of Globigerinoides ruber pink (δ18Oindiv) during dry episodes show a total range and variance of 2.3‰ and 0.25 (n = 121), indicating that seasonal contrast of sea surface freshening was significantly reduced during Heinrich events relative to that of interstadials which show a total range and variance of 3.35‰ and 0.42 (n = 140). On the basis of the timing and magnitude of changes in the monsoon record, it is evident that northern high latitude climate was the most dominant control on the West African monsoon variability. However, a southern high latitude imprint is also apparent during some episodes. This centennially resolved climate record demonstrates that the equatorial West African monsoon experienced profound changes in the amount, seasonal contrast, and moisture source of summer monsoon precipitation during the last glacial. The most plausible mechanism is a large-scale southward displacement of the monsoon trough, most likely initiated by large-scale reorganization of atmospheric

  18. A Comparison of Phenotypic Traits Related to Trypanotolerance in Five West African Cattle Breeds Highlights the Value of Shorthorn Taurine Breeds

    PubMed Central

    Berthier, David; Peylhard, Moana; Dayo, Guiguigbaza-Kossigan; Flori, Laurence; Sylla, Souleymane; Bolly, Seydou; Sakande, Hassane; Chantal, Isabelle; Thevenon, Sophie

    2015-01-01

    Background Animal African Trypanosomosis particularly affects cattle and dramatically impairs livestock development in sub-Saharan Africa. African Zebu (AFZ) or European taurine breeds usually die of the disease in the absence of treatment, whereas West African taurine breeds (AFT), considered trypanotolerant, are able to control the pathogenic effects of trypanosomosis. Up to now, only one AFT breed, the longhorn N’Dama (NDA), has been largely studied and is considered as the reference trypanotolerant breed. Shorthorn taurine trypanotolerance has never been properly assessed and compared to NDA and AFZ breeds. Methodology/Principal Findings This study compared the trypanotolerant/susceptible phenotype of five West African local breeds that differ in their demographic history. Thirty-six individuals belonging to the longhorn taurine NDA breed, two shorthorn taurine Lagune (LAG) and Baoulé (BAO) breeds, the Zebu Fulani (ZFU) and the Borgou (BOR), an admixed breed between AFT and AFZ, were infected by Trypanosoma congolense IL1180. All the cattle were genetically characterized using dense SNP markers, and parameters linked to parasitaemia, anaemia and leukocytes were analysed using synthetic variables and mixed models. We showed that LAG, followed by NDA and BAO, displayed the best control of anaemia. ZFU showed the greatest anaemia and the BOR breed had an intermediate value, as expected from its admixed origin. Large differences in leukocyte counts were also observed, with higher leukocytosis for AFT. Nevertheless, no differences in parasitaemia were found, except a tendency to take longer to display detectable parasites in ZFU. Conclusions We demonstrated that LAG and BAO are as trypanotolerant as NDA. This study highlights the value of shorthorn taurine breeds, which display strong local adaptation to trypanosomosis. Thanks to further analyses based on comparisons of the genome or transcriptome of the breeds, these results open up the way for better knowledge

  19. Attitudes to malaria, traditional practices and bednets (mosquito nets) as vector control measures: a comparative study in five west African countries.

    PubMed

    Aikins, M K; Pickering, H; Greenwood, B M

    1994-04-01

    Five West African communities were visited to assess the knowledge of the cause of malaria and to document traditional ways of treating and preventing the infection. Knowledge of the cause of malaria was low in the five communities visited. People were more concerned about mosquitoes being a nuisance than a cause of the infection. Various herbs were used as mosquito repellents. Malaria was treated by a number of traditional practices, including herbal remedies. Bednets were used to a varying extent, from 44% Ghana to 86% Gambia, in each community to protect against mosquito bites but also for other purposes such as privacy, decoration and protection from roof debris dropping on the bed.

  20. Robustness and strategies of adaptation among farmer varieties of African Rice (Oryza glaberrima) and Asian Rice (Oryza sativa) across West Africa.

    PubMed

    Mokuwa, Alfred; Nuijten, Edwin; Okry, Florent; Teeken, Béla; Maat, Harro; Richards, Paul; Struik, Paul C

    2013-01-01

    This study offers evidence of the robustness of farmer rice varieties (Oryza glaberrima and O. sativa) in West Africa. Our experiments in five West African countries showed that farmer varieties were tolerant of sub-optimal conditions, but employed a range of strategies to cope with stress. Varieties belonging to the species Oryza glaberrima - solely the product of farmer agency - were the most successful in adapting to a range of adverse conditions. Some of the farmer selections from within the indica and japonica subspecies of O. sativa also performed well in a range of conditions, but other farmer selections from within these two subspecies were mainly limited to more specific niches. The results contradict the rather common belief that farmer varieties are only of local value. Farmer varieties should be considered by breeding programmes and used (alongside improved varieties) in dissemination projects for rural food security.

  1. Assessment of the petroleum, coal, and geothermal resources of the Economic Community of West African States (ECOWAS) region

    USGS Publications Warehouse

    Mattick, R. E.

    1982-01-01

    Approximately 85 percent of the land area of the ECOWAS (Economic Community of West African States) region is covered by basement rocks (igneous and highly metamorphosed rocks) or relatively thin layers of Paleozoic, Upper Precambrian, and 'Continental Intercalaire? sedimentary rocks. These areas have little or no petroleum potential. Areas of the ECOWAS region that have potential for petroleum production or potential for increased petroleum production include the narrow belt of sedimentary rocks that stretches along the continental margin from Mauritania to Nigeria and the Niger Delta and the Benue depression. The Senegal Basin, located on the continental margin of Mauritania, Senegal, Gambia, Guinea Bissau, and Guinea, has been intensely explored by the oil industry and most of the larger structures onshore and on the shelf probably have been tested by drilling with little or no resulting commercial production. Unless basic ideas pertaining to the petroleum geology of the Senegal Basin are revised, future discoveries are expected to be limited to small fields overlooked by industry at a time when petroleum prices were low. On the continental shelf of Sierra Leone and the continental shelf of northeast and central Liberia, the sedimentary rocks are relatively thin, and industry has shown little interest in the area. On the continental rise of these countries, however, the sedimentary section, deposited in a complex fault-block system, increases in thickness. A renewal of industry interest in this deep-water area will probably follow further development of deep-water production technology. A recent oil discovery on the continental slope off the Ivory Coast is expected to spur further exploration offshore of southeastern Liberia, Ivory Coast, Ghana, Togo, and Benin. This relatively unexplored area in the Gulf of Guinea has good possibilities .for the discovery of giant oil fields. Nigeria's oil development from the Niger Delta may have peaked, as 13 of 14 giant oil

  2. Cytogenetics of the Anopheles gambiae complex in Sudan, with special reference to An. arabiensis: relationships with East and West African populations.

    PubMed

    Petrarca, V; Nugud, A D; Ahmed, M A; Haridi, A M; Di Deco, M A; Coluzzi, M

    2000-06-01

    The species composition of malaria vector mosquitoes belonging to the Anopheles gambiae complex (Diptera: Culicidae) from >40 localities in Sudan, representing most ecological situations, was determined by analysis of ovarian polytene chromosomes. Of 2162 females, 93% were identified as An. arabiensis Patton and 7% were An. gambiae Giles sensu stricto. No hybrids were found between the two species. Anopheles arabiensis occurred in all but two sites, whereas An. gambiae s.s. was effectively limited to the southernmost, more humid localities. For chromosomal paracentric inversions, the degree of polymorphism was low in An. gambiae s.s. (inversions 2La, 2Rb and 2Rd), higher in An. arabiensis (inversions Xe, 2Ra, b, bc, d1, s; 3Ra, d). Anopheles gambiae samples from Sudan were all apparently panmictic, i.e. they did not show restricted gene flow such as observed among West African populations (interpreted as incipient speciation). Chromosomal inversion patterns of An. gambiae in southern Sudan showed characteristics of intergrading Savanna/Forest populations similar to those observed in comparable eco-climatic situations of West Africa. Anopheles arabiensis was polymorphic for inversion systems recorded in West Africa (2Ra, 2Rb, 2Rdl, 3Ra) and for a novel 2Rs polymorphism, overlapping with inversion systems 2Rb and 2Rd1. Samples carrying the 2Rs inversion were mostly from Khashm-el-Girba area in central-eastern Sudan. In the great majority of the samples all polymorphic inversions were found to be in Hardy-Weinberg equilibrium. Sudan populations of An. arabiensis should therefore be considered as generally panmictic. Anopheles arabiensis shows more inversion polymorphism in west than in east African populations. Sudan populations have more evident similarities with those from westwards than those from eastwards of the Great Rift Valley. The possible influence of the Rift on evolution of An. arabiensis is discussed.

  3. Mat-related sedimentary structures in Neoproterozoic peritidal passive margin deposits of the West African Craton (Anti-Atlas, Morocco)

    NASA Astrophysics Data System (ADS)

    Bouougri, E.; Porada, H.

    2002-11-01

    Proterozoic inliers in the central Anti-Atlas mountains expose predominantly siliciclastic sedimentary successions deposited in peritidal zones along the Neoproterozoic continental margin of the West African Craton (WAC). The low-grade metamorphic and modestly deformed sediments contain a wealth of sedimentary structures related to the former presence and activities of microbial mats and respective physicobiological processes. The well-preserved structures include wrinkle structures, erosion marks, microbial sand chips, spindle-shaped and subcircular microbial shrinkage cracks, and possibly gas domes and cabbage-head structures. Thin sections exhibit mat fragments and dispersed grains of hematite/limonite after pyrite in fine-grained quartzitic storm deposits. Post-storm layers frequently consist of matrix-supported sand-sized to silt-sized grains and are overlain by argillaceous veneers including isolated silt-sized grains and black carbonaceous laminae. The muddy veneers are considered to represent compacted stacks of microbial mats (biolaminites), which colonized and biostabilized storm and post-storm layers, and thus prevented them from eroding. In the absence of grazing and burrowing organisms and at suitable depositional and hydrodynamic conditions, it may be expected that Proterozoic microbial mats extensively grew from the supratidal to the intertidal zones and occasionally, e.g. behind protective barriers, in the subtidal zone and beyond. Mat-related structures, however, need specific conditions for their formation and preservation: Wrinkle structures, erosion marks, and microbial sand chips require tractional currents and soon deposition and burial, respectively. Such conditions are preferably met in intertidal and supratidal zones. Spindle-shaped and subcircular cracks require mat shrinkage due to either desiccation or "syneresis". Crack propagation implies progressive shrinkage, while superposition of crack generations indicates repeated alternation

  4. Kinematics of a growth fault/raft system on the West African margin using 3-D restoration

    NASA Astrophysics Data System (ADS)

    Rouby, Delphine; Raillard, Stéphane; Guillocheau, François; Bouroullec, Renaud; Nalpas, Thierry

    2002-04-01

    The ability to quantify the movement history associated with growth structures is crucial in the understanding of fundamental processes such as the growth of folds or faults in 3-D. In this paper, we present an application of an original approach to restore in 3-D a listric growth fault system resulting from gravity-induced extension located on the West African margin. Our goal is to establish the 3-D structural framework and kinematics of the study area. We construct a 3-D geometrical model of the fault system (from 3-D seismic data), then restore six stratigraphic surfaces and reconstruct the 3-D geometry of the system at six incremental steps of its history. The evolution of the growth fault/raft system corresponds to the progressive separation of two rafts by regional extension, resulting in the development of an intervening basin located between them that evolved in three main stages: (1) the rise of an evaporite wall, (2) the development of a symmetric basin as the elevation of the diapir is reduced and buried, and (3) the development of asymmetric basins related to two systems of listric faults (the main fault F1 and the graben located between the rollovers and the lower raft). Important features of the growth fault/raft system could only be observed in 3-D and with increments of deformation restored. The rollover anticline (associated with the listric fault F1) is composed of two sub-units separated by an E-W oriented transverse graben indicating that the displacement field was divergent in map view. The rollover units are located within the overlap area of two fault systems and displays a 'mock-turtle' anticline structure. The seaward translation of the lower raft is associated with two successive vertical axis rotations in the opposite sense (clockwise then counter-clockwise by about 10°). This results from the fact that the two main fault systems developed successively. Fault system F1 formed during the Upper Albian, and the graben during the Cenomanian

  5. The Guiana and the West African Shield Palaeoproterozoic grouping: new palaeomagnetic data for French Guiana and the Ivory Coast

    NASA Astrophysics Data System (ADS)

    Nomade, Sébastien; Chen, Yan; Pouclet, André; Féraud, Gilbert; Théveniaut, Hervé; Daouda, Bertin Yao; Vidal, Max; Rigolet, Cécile

    2003-09-01

    The aim of this study is to document the Palaeoproterozoic palaeomagnetic database for the Guiana and West African Shields in order to better understand the paleogeographic evolution of these two cratons. A total of 59 sites were sampled (33 in French Guiana and 26 in the Ivory Coast) in granites and metavolcanic rocks. Magnetic, petrographic and palaeomagnetic investigations were carried out on these rocks. Magnetic experiments and petrographic observations show that undeformed magnetite is the main magnetic remanent carrier in granites of French Guiana and both magnetite and haematite in rocks from the Ivory Coast. Both thermal and magnetic alternating-field demagnetizations were applied to the rocks. Four high-temperature magnetic remanent directions were isolated in French Guiana and the Ivory Coast. These directions are distinct from the present Earth's field and to the local Early Jurassic palaeomagnetic components. Reversal and contact tests were obtained for the collection from French Guiana. Based on these arguments and mineralogical investigations, we propose that the magnetic remanence represent a Palaeoproterozoic magnetization. Four virtual palaeomagnetic poles were calculated: GUI1, GUI2 for French Guiana; IC1 and IC2 for the Ivory Coast with their corresponding coordinates: GUI1: λGUI1=-62°N, φGUI1= 61°E, k= 18, A95= 10°, N= 15; GUI2: λGUI2=-5°N, φGUI2= 50°E, k= 26, A95= 18°, N= 5; IC1: λIC1=-82°N, φIC1= 292°N, k= 28, A95= 13°, N= 6; IC2: λIC2=-25°N, φIC2= 83°E, k= 11, A95= 16°, N= 9. The magnetization age ranged from 2.04 to 1.97 Ga for the French Guiana poles (40Ar/39Ar) and between 2.10 to 2.00 Ga for the Ivory Coast poles (startigraphic ages). Combining these new palaeomagnetic poles and previously published data, two apparent polar wander paths were proposed for these two shields. The comparison of these two Palaeoproterozoic paths seems to indicate that the two cratons belonged to the same block at about 2.00 Ga but

  6. Assessment of the potential for international dissemination of Ebola virus via commercial air travel during the 2014 west African outbreak

    PubMed Central

    Bogoch, Isaac I; Creatore, Maria I; Cetron, Martin S; Brownstein, John S; Pesik, Nicki; Miniota, Jennifer; Tam, Theresa; Hu, Wei; Nicolucci, Adriano; Ahmed, Saad; Yoon, James W; Berry, Isha; Hay, Simon I; Anema, Aranka; Tatem, Andrew J; MacFadden, Derek; German, Matthew; Khan, Kamran

    2015-01-01

    Summary Background The WHO declared the 2014 west African Ebola epidemic a public health emergency of international concern in view of its potential for further international spread. Decision makers worldwide are in need of empirical data to inform and implement emergency response measures. Our aim was to assess the potential for Ebola virus to spread across international borders via commercial air travel and assess the relative efficiency of exit versus entry screening of travellers at commercial airports. Methods We analysed International Air Transport Association data for worldwide flight schedules between Sept 1, 2014, and Dec 31, 2014, and historic traveller flight itinerary data from 2013 to describe expected global population movements via commercial air travel out of Guinea, Liberia, and Sierra Leone. Coupled with Ebola virus surveillance data, we modelled the expected number of internationally exported Ebola virus infections, the potential effect of air travel restrictions, and the efficiency of airport-based traveller screening at international ports of entry and exit. We deemed individuals initiating travel from any domestic or international airport within these three countries to have possible exposure to Ebola virus. We deemed all other travellers to have no significant risk of exposure to Ebola virus. Findings Based on epidemic conditions and international flight restrictions to and from Guinea, Liberia, and Sierra Leone as of Sept 1, 2014 (reductions in passenger seats by 51% for Liberia, 66% for Guinea, and 85% for Sierra Leone), our model projects 2·8 travellers infected with Ebola virus departing the above three countries via commercial flights, on average, every month. 91 547 (64%) of all air travellers departing Guinea, Liberia, and Sierra Leone had expected destinations in low-income and lower-middle-income countries. Screening international travellers departing three airports would enable health assessments of all travellers at highest risk

  7. Testicular biochemicals, sperm reserves and daily sperm production of West African dwarf bucks fed varied levels of dietary aflatoxin.

    PubMed

    Ewuola, E O; Jimoh, O A; Bello, A D; Bolarinwa, A O

    2014-08-01

    An experiment was conducted with twenty West African dwarf (WAD) bucks (5-6 months old) to assess reproductive potentials of growing WAD bucks to varied dietary aflatoxin of 0 μg/kg, 50 μg/kg, 100 μg/kg and 150 μg/kg containing in diets 1 (control) 2, 3 and 4 respectively, for a period of 12 weeks. At the end of the 12th week, the reproductive tracts of bucks were excised and homogenised in physiological saline for assessment of glucose, total protein and testosterone concentration, gonadal and extra gonadal sperm reserves. Results showed that gonadal and extra-gonadal sperm reserves of goats fed control diet (2.71×10(9) and 3.07×10(9) spermatozoa respectively) were superior (p<0.05) to those fed 50 μg/kg, 100 μg/kg and 15 0μg/kg [(1.59×10(9) and 2.33×10(9)), (1.09×10(9) and 2.45×10(9)) and (1.00×10(9) and 1.41×10(9)) spermatozoa respectively]. Daily sperm production of bucks fed the control diet was significantly (p<0.05) higher (7.60×10(8) spermatozoa/testis) than those fed 50 μg/kg (4.47×10(8)), 100 μg/kg (3.07×10(8)) and 150 μg/kg (2.80×10(8) spermatozoa/testis). Sperm production efficiency also follows the same trend as daily sperm production. Glucose and total protein concentration in the testes declined significantly as the aflatoxin level increases in the diets. Testosterone level was significantly lower in goats fed 100 μg/kg than others. The study suggest that exposure of male goats to dietary aflatoxin up to 50 μg/kg diet will reduced testicular biochemical and testosterone with resultant depression in sperm storage capability and daily sperm production in the animals.

  8. Differences in T-cell responses between Mycobacterium tuberculosis and Mycobacterium africanum-infected patients.

    PubMed

    Tientcheu, Leopold D; Sutherland, Jayne S; de Jong, Bouke C; Kampmann, Beate; Jafali, James; Adetifa, Ifedayo M; Antonio, Martin; Dockrell, Hazel M; Ota, Martin O

    2014-05-01

    In The Gambia, Mycobacterium tuberculosis (Mtb) and Mycobacterium africanum (Maf) are major causes of tuberculosis (TB). Maf is more likely to cause TB in immune suppressed individuals, implying differences in virulence. Despite this, few studies have assessed the underlying immunity to the two pathogens in human. In this study, we analyzed T-cell responses from 19 Maf- and 29 Mtb-infected HIV-negative patients before and after TB chemotherapy following overnight stimulation of whole blood with TB-specific antigens. Before treatment, percentages of early secreted antigenic target-6(ESAT-6)/culture filtrate protein-10(CFP-10) and purified protein derivative-specific single-TNF-α-producing CD4(+) and CD8(+) T cells were significantly higher while single-IL-2-producing T cells were significantly lower in Maf- compared with Mtb-infected patients. Purified protein derivative-specific polyfunctional CD4(+) T cells frequencies were significantly higher before than after treatment, but there was no difference between the groups at both time points. Furthermore, the proportion of CD3(+) CD11b(+) T cells was similar in both groups pretreatment, but was significantly lower with higher TNF-α, IL-2, and IFN-γ production in Mtb- compared with that of Maf-infected patients posttreatment. Our data provide evidence of differences in T-cell responses to two mycobacterial strains with differing virulence, providing some insight into TB pathogenesis with different Mtb strains that could be prospectively explored as biomarkers for TB protection or susceptibility.

  9. Gondwanan basement terranes of the Variscan-Appalachian orogen: Baltican, Saharan and West African hafnium isotopic fingerprints in Avalonia, Iberia and the Armorican Terranes

    NASA Astrophysics Data System (ADS)

    Henderson, Bonnie J.; Collins, William Joseph; Murphy, James Brendan; Gutierrez-Alonso, Gabriel; Hand, Martin

    2016-06-01

    Iberia, Avalonia and the "Armorican" terranes form key constituents of the Variscan-Appalachian orogen, but their Neoproterozoic origins along the northern Gondwanan margin continue to be strongly debated. Here, we present a new detrital zircon U-Pb-Hf dataset from Neoproterozoic-Silurian sedimentary sequences in NW Iberia and Avalonia, in conjunction with the comprehensive existing datasets from potential source cratons, to demonstrate that the provenance of each terrane is relatively simple and can be traced back to three major cratons. The enigmatic Tonian-Stenian detrital zircons in autochthonous Iberian rocks were derived from the Saharan metacraton in the latest Neoproterozoic-early Cambrian. Avalonia is commonly considered to have been derived from the Amazonian margin of Gondwana, but the hafnium isotopic characteristics of the detrital zircon grains in early Neoproterozoic rocks bear much stronger similarities to Baltica. The hafnium isotopic array also suggests the early Avalonian oceanic arc was built on a sliver of "Grenvillian-type crust" (~ 2.0-1.0 Ga) possibly of Baltican affinity at ~ 800 Ma, prior to accretion with a continental margin at ~ 640 Ma. The Upper Allochthon of Iberia is frequently linked to the West African Craton in the late Neoproterozoic-early Cambrian, however the hafnium isotopic array presented here does not support this connection; rather it is more similar to the hafnium array from Avalonia. The Armorican terranes have strong detrital zircon isotopic links to the West African Craton during the late Neoproterozoic-Cambrian.

  10. Deep crustal structure of the North-West African margin from combined wide-angle and reflection seismic data (MIRROR seismic survey)

    NASA Astrophysics Data System (ADS)

    Biari, Y.; Klingelhoefer, F.; Sahabi, M.; Aslanian, D.; Schnurle, P.; Berglar, K.; Moulin, M.; Mehdi, K.; Graindorge, D.; Evain, M.; Benabdellouahed, M.; Reichert, C.

    2015-08-01

    The structure of the Moroccan and Nova Scotia conjugate rifted margins is of key importance for understanding the Mesozoic break-up and evolution of the northern central Atlantic Ocean basin. Seven combined multichannel reflection (MCS) and wide-angle seismic (OBS) data profiles were acquired along the Atlantic Moroccan margin between the latitudes of 31.5° and 33° N during the MIRROR seismic survey in 2011, in order to image the transition from continental to oceanic crust, to study the variation in crustal structure, and to characterize the crust under the West African Coast Magnetic Anomaly (WACMA). The data were modeled using a forward modeling approach. The final models image crustal thinning from 36 km thickness below the continent to approximately 8 km in the oceanic domain. A 100 km wide zone characterized by rough basement topography and high seismic velocities up to 7.4 km/s in the lower crust is observed westward of the West African Coast Magnetic Anomaly. No basin underlain by continental crust has been imaged in this region, as has been identified north of our study area. Comparison to the conjugate Nova Scotian margin shows a similar continental crustal thickness and layer geometry, and the existence of exhumed and serpentinized upper mantle material on the Canadian side only. The oceanic crustal thickness is lower on the Canadian margin.

  11. Antibiotic sensitivity and sequence amplification patterns of genes in multidrug resistant enterobacteria isolates from processed foods in some West African countries.

    PubMed

    Owoseni, Abimbola Adetokunboh; Onilude, Abiodun Anthony

    2011-01-01

    Diarrhoea, dysentery and other diseases due to other enteric bacteria have reportedly been found to resist chemotherapeutic treatment in some West African communities with fatal consequences in some cases. This study was carried out to determine multidrug resistance patterns of Enterobacteria isolates from processed ready-to-eat foods. Indigenously processed food samples of different types were collected from two Francophone and two Anglophone countries in the West African sub-region during the wet and dry seasons of a sampling period of two years. Enterobacteria were isolated from the samples using standard techniques. Amplification of chromosomal DNA of the isolates using the Polymerase Chain Reaction was carried out. The results obtained were subjected to statistical analyses. All isolates showed resistance to cefuroxime (90.7%), nitrofurantoin (90.6%), augmentin (86.1%) and ampicillin (51.2%) while all were sensitive to gentamycin and ciprofloxacin. There was amplification indicating the presence of invA gene at a position of 240 bp. There was no amplification at all for the spvC gene in any of the isolates tested. Multidrug resistant enteric bacteria in these foods containing the invA gene could lead to infections with uncontrolled antibiotic use. The presence of enteric bacteria in the foods analyzed which provide undeniable evidence of the poor microbiological quality of these foods could form the basis of a useful databank in formulation of food-borne disease control and prevention strategies.

  12. Determinants of early introduction of solid, semi-solid or soft foods among infants aged 3-5 months in four Anglophone West African countries.

    PubMed

    Issaka, Abukari I; Agho, Kingsley E; Page, Andrew N; Burns, Penelope; Stevens, Garry J; Dibley, Michael J

    2014-07-14

    This study was conducted to explore and identify factors associated with the practice of early introduction of solid, semi-solid or soft foods among infants aged 3-5 months in four Anglophone West African countries. Data sources for the analyses were the latest Demographic and Health Survey datasets of the 4 countries, namely Ghana (GDHS, 2008), Liberia (LDHS, 2007), Nigeria (NDHS, 2013) and Sierra Leone (SLDHS, 2008). Multiple logistic regression methods were used to analyze the factors associated with early introduction of solid, semi-solid or soft foods among infants aged 3-5 months, using individual-, household- and community-level determinants. The sample consisted of 2447 infants aged 3-5 months from four Anglophone West African countries: 166 in Ghana, 263 in Liberia, 1658 in Nigeria and 360 in Sierra Leone. Multivariable analyses revealed the individual factors associated with early introduction of solid, semi-solid or soft foods in these countries. These included increased infant's age, diarrhea, acute respiratory infection and newborns perceived to be small by their mothers. Other predictors of early introduction of solid, semi-solid or soft foods were: mothers with no schooling, young mothers and fathers who worked in an agricultural industry. Public health interventions to improve exclusive breastfeeding practices by discouraging early introduction of solid, semi-solid or soft foods are needed in all 4 countries, targeting especially mothers at risk of introducing solid foods to their infants early.

  13. Determinants of Early Introduction of Solid, Semi-Solid or Soft Foods among Infants Aged 3–5 Months in Four Anglophone West African Countries

    PubMed Central

    Issaka, Abukari I.; Agho, Kingsley E.; Page, Andrew N.; Burns, Penelope; Stevens, Garry J.; Dibley, Michael J.

    2014-01-01

    This study was conducted to explore and identify factors associated with the practice of early introduction of solid, semi-solid or soft foods among infants aged 3–5 months in four Anglophone West African countries. Data sources for the analyses were the latest Demographic and Health Survey datasets of the 4 countries, namely Ghana (GDHS, 2008), Liberia (LDHS, 2007), Nigeria (NDHS, 2013) and Sierra Leone (SLDHS, 2008). Multiple logistic regression methods were used to analyze the factors associated with early introduction of solid, semi-solid or soft foods among infants aged 3–5 months, using individual-, household- and community-level determinants. The sample consisted of 2447 infants aged 3–5 months from four Anglophone West African countries: 166 in Ghana, 263 in Liberia, 1658 in Nigeria and 360 in Sierra Leone. Multivariable analyses revealed the individual factors associated with early introduction of solid, semi-solid or soft foods in these countries. These included increased infant’s age, diarrhea, acute respiratory infection and newborns perceived to be small by their mothers. Other predictors of early introduction of solid, semi-solid or soft foods were: mothers with no schooling, young mothers and fathers who worked in an agricultural industry. Public health interventions to improve exclusive breastfeeding practices by discouraging early introduction of solid, semi-solid or soft foods are needed in all 4 countries, targeting especially mothers at risk of introducing solid foods to their infants early. PMID:25025297

  14. In vitro susceptibility of Mycobacterium tuberculosis, Mycobacterium africanum, Mycobacterium bovis, Mycobacterium avium, Mycobacterium fortuitum, and Mycobacterium chelonae to ticarcillin in combination with clavulanic acid.

    PubMed Central

    Casal, M J; Rodriguez, F C; Luna, M D; Benavente, M C

    1987-01-01

    The in vitro susceptibility of Mycobacterium tuberculosis, Mycobacterium bovis, Mycobacterium africanum, Mycobacterium avium, Mycobacterium fortuitum, and Mycobacterium chelonae (M. chelonei) to ticarcillin in combination with calvulanic acid (CA) was studied by the agar dilution method. All the M. tuberculosis, M. bovis, and M. africanum strains were inhibited at a ticarcillin concentration of 32 micrograms/ml or lower in combination with 5 micrograms of CA. M. chelonae and M. avium strains proved resistant to more than 128 micrograms of ticarcillin plus 5 micrograms of CA per ml. M. fortuitum strains needed 128 micrograms of ticarcillin plus 5 micrograms of CA to inhibit approximately 30% of the isolates. PMID:3105441

  15. Metamorphic record and Thermo-mechanical modelling of lower crust exhumation during the Palaeoproterozoic Eburnean orogeny, West African Craton

    NASA Astrophysics Data System (ADS)

    Gerbault, Muriel; Ganne, Jerome; Block, Sylvain

    2014-05-01

    A thermo-mechanical interpretation of the metamorphic evolution of moderate- to high-pressure volcano-sedimentary rocks (6-8 to >10 Kb) in the Birimian Province (2.2-2.0 Ga) of the West African Craton is explored in terms of burial and exhumation processes. Metamorphic data collected in Burkina Faso, southwest Ghana and eastern Senegal suggest that during the Eburnean orogeny (~2.1 Ga),this Palaeoproterozoic Birimian crust was dominated by moderate apparent geothermal gradients of 20-30°C/km (M2a), that produced greenschist- to amphibolite-facies metamorphic assemblages associated with regional shortening and granitoid intrusions. The M2a gradient is superimposed on a colder thermal regime (M1 : <10-15 °C/km) that produced high-P greenschist- to blueschist-facies metamorphic assemblages, and which most likely recorded the earlier formation of the protolith. The geodynamical origin of M1 is not directly addressed here. Thermo-mechanical two-dimensional numerical models were built in order to test whether late-stage compressional tectonics could generate the exhumation of meta-sediments, collected in Ca0-poor granitoids and which record elevated metamorphic pressures (P> 6-8 Kb). The poor data quality provide limited constraints on the appropriate initial setup conditions, and a number of tests have led us to conceptualize the spatial distribution of a hypothezised succession of volcanic island arcs emplaced on top of CaO rich TTG (Tonalite- Trondjhemite-Granodiorite suites) basement, tectonically paired with sedimentary basins. We postulated therefore the preexistence of wide (about 250 km) and thick flexural sedimentary basins (depth 15 km) in an orogenic mafic crust (about 20 km thick), underplated by a more felsic and lighter layer representing a TTG melange. The numerical results show that a mechanism of burial, heating and exhumation of meta-sediments can occur by simultaneous folding and gravitational instabilities within the broad extent of the basin

  16. Transpressional granite-emplacement model: Structural and magnetic study of the Pan-African Bandja granitic pluton (West Cameroon)

    NASA Astrophysics Data System (ADS)

    Sandjo, A. F. Yakeu; Njanko, T.; Njonfang, E.; Errami, E.; Rochette, P.; Fozing, E.

    2016-02-01

    The Pan-African NE-SW elongated Bandja granitic pluton, located at the western part of the Pan-African belt in Cameroon, is a K-feldspar megacryst granite. It is emplaced in banded gneiss and its NW border underwent mylonitization. The magmatic foliation shows NE-SW and NNE-SSW strike directions with moderate to strong dip respectively in its northern and central parts. This mostly, ferromagnetic granite displays magnetic fabrics carried by magnetite and characterized by (i) magnetic foliation with best poles at 295/34, 283/33 and 35/59 respectively in its northern, central and southern parts and (ii) a subhorizontal magnetic lineation with best line at 37/8, 191/9 and 267/22 respectively in the northern, central and southern parts. Magnetic lineation shows an `S' shape trend that allows to (1) consider the complete emplacement and deformation of the pluton during the Pan-African D 2 and D 3 events which occurred in the Pan-African belt in Cameroon and (2) reorganize Pan-African ages from Nguiessi Tchakam et al. (1997) compared with those of the other granitic plutons in the belt as: 686 ±17 Ma (Rb/Sr) for D 1 age of metamorphism recorded in gneiss; and the period between 604-557 Ma for D 2-D 3 emplacement and deformation age of the granitic pluton in a dextral ENE-WSW shear movement.

  17. Life Expressions: West African Art in the Collection of the Seattle Art Museum. Art for the Individual. Art for the Community. Art for Gods and Spirits. Curriculum Resource Unit.

    ERIC Educational Resources Information Center

    Ross, Annie; And Others

    This teacher resource packet, which includes 20 color slides with a descriptive script and comprehensive lesson guide, aims at engaging students in a study of the people, art, and culture of several West African nations, including the countries of Cameroon, Ghana, Liberia, Mali, and Nigeria. The packet, designed for use by general classroom…

  18. "If We Can't Do It, Our Children Will Do It One Day": A Qualitative Study of West African Immigrant Parents' Losses and Educational Aspirations for Their Children

    ERIC Educational Resources Information Center

    Roubeni, Sonia; De Haene, Lucia; Keatley, Eva; Shah, Nira; Rasmussen, Andrew

    2015-01-01

    This study examined migration narratives of West African immigrants for the connections between experiences of loss and educational aspirations for their children. The qualitative design consisted of three interviews per family in which parents (N = 20, 12 families) were asked to narrate their families' migration histories. Transcripts were…

  19. Contrasting conditions of surface water balance in wet years and dry years as a possible land surface-atmosphere feedback mechanism in the West African Sahel

    NASA Technical Reports Server (NTRS)

    Lare, A. R.; Nicholson, S. E.

    1994-01-01

    The climate of West Africa, in particular the Sahel, is characterized by multiyear persistence of anomalously wet or dry conditions. Its Southern Hemisphere counterpart, the Kalahari, lacks the persistence that is evident in the Sahel even though both regions are subject to similar large-scale forcing. It has been suggested that land surface-atmosphere feedback contributes to this persistence and to the severity of drought. In this study, surface energy and water balance are quantified for nine stations along a latitudinal transect that extends from the Sahara to the Guinea coast. In the wetter regions of West Africa, the difference between wet and dry years is primarily reflected in the magnitude of runoff. For the Sahel and drier locations, evapotranspiration and soil moisture are more sensitive to rainfall anomalies. The increase in evapotranspiration, and hence latent heating, over the Sahel in wet years alters the thermal structure and gradients of the overlying atmosphere and thus the strength of the African easterly jet (AEJ) at 700 mb. The difference between dry and wet Augusts corresponds to a decrease in magnitude of the AEJ at 15 deg N on the order of 2.6 m/s, which is consistent with previous studies of observed winds. Spatial patterns were also developed for surface water balance parameters for both West Africa and southern Africa. Over southern Africa, the patterns are not as spatially homogeneous as those over West Africa and are lower in magnitude, thus supporting the suggestion that the persistence of rainfall anomalies in the Sahel might be due, at least in part, to land-atmosphere feedback, and that the absence of such persistence in the Kalahari is a consequence of less significant changes in surface water and energy balance.

  20. Characterization of the impact of land degradation in the Sahel on the West African monsoon using an ensemble of climate models from the WAMME project

    NASA Astrophysics Data System (ADS)

    Boone, A. A.; Xue, Y.; Ruth, C.; De Sales, F.; Hagos, S.; Mahanama, S. P. P.; Schiro, K.; Song, G.; Wang, G.; Koster, R. D.; Mechoso, C. R.

    2014-12-01

    There is increasing evidence from numerical studies that anthropogenic land-use and land-cover changes (LULCC) can potentially induce significant variations on the regional scale climate. However, the magnitude of these variations likely depends on the local strength of the coupling between the surface and the atmosphere, the magnitude of the surface biophysical changes and how the key processes linking the surface with the atmosphere are parameterized within a particular model framework. One key hot-spot which has received considerable attention is the Sahelian region of West Africa, for which numerous studies have reported a significant increase in anthropogenic pressure on the already limited natural resources in this region, notably in terms of land use conversion and degradation. Thus, there is a pressing need to better understand the impacts of potential land degradation on the West African Monsoon (WAM) system. One of the main goals of the West African Monsoon Modeling andEvaluation project phase 2 (WAMMEII) is to provide basic understandingof LULCC on the regional climate over West Africa, and to evaluate thesensitivity of the seasonal variability of the WAM to LULCC. Theprescribed LULCC is based on recent 50 year period which represents amaximum feasible degradation scenario. In the current study, the LULCCis applied to five state of the art global climate models over afive-year period. The imposed LULCC results in a model-average 5-7%increase in surface albedo: the corresponding lower surface netradiation mainly results in a significant reduction in surfaceevaporation (upwards of 1 mm per day over a large part of the Sahel)which leads to less convective heating of the atmosphere, lowermoisture convergence, increased subsidence and reduced cloud coverover the LULCC zone. The overall impact can be characterized as asubstantial drought effect resulting in a reduction in annual rainfallof 20-40% in the Sahel and a southward shift of the monsoon. In

  1. Characterization of the key aroma compounds in dried fruits of the West African peppertree Xylopia aethiopica (Dunal) A. Rich (Annonaceae) using aroma extract dilution analysis.

    PubMed

    Tairu, A O; Hofmann, T; Schieberle, P

    1999-08-01

    Application of aroma extract dilution analysis on an extract of the dried fruits of the West African peppertree Xylopia aethiopica obtained by extraction with diethyl ether followed by sublimation in vacuo revealed 28 odor-active compounds in the flavor dilution (FD) factor range of 4-8192, all of which could be identified. The highest FD factor was found for linalol (floral), followed by (E)-beta-ocimene (flowery), alpha-farnesene (sweet, flowery), beta-pinene (terpeny), alpha-pinene (pine needle-like), myrtenol (flowery), and beta-phellandrene (terpeny). Vanillin (vanilla-like) and 3-ethylphenol (smoky, phenolic) showing somewhat lower FD factors (FD = 128) were detected for the first time as constituents of the dried fruit. PMID:10552646

  2. Petrochemical and petrophysical characterization of the lower crust and the Moho beneath the West African Craton, based on Xenoliths from Kimberlites

    NASA Technical Reports Server (NTRS)

    Haggerty, Stephen E.; Toft, Paul B.

    1988-01-01

    Additional evidence to the composition of the lower crust and uppermost mantle was presented in the form of xenolith data. Xenoliths from the 2.7-Ga West African Craton indicate that the Moho beneath this shield is a chemically and physically gradational boundary, with intercalations of garnet granulite and garnet eclogite. Inclusions in diamonds indicate a depleted upper mantle source, and zenolith barometry and thermometry data suggest a high mantle geotherm with a kink near the Moho. Metallic iron in the xenoliths indicates that the uppermost mantle has a significant magnetization, and that the depth to the Curie isotherm, which is usually considered to be at or above the Moho, may be deeper than the Moho.

  3. The Experience of Antiretroviral Treatment for Black West African Women who are HIV Positive and Living in London: An Interpretative Phenomenological Analysis.

    PubMed

    Spiers, Johanna; Smith, Jonathan A; Poliquin, Elizabeth; Anderson, Jane; Horne, Rob

    2016-09-01

    Antiretroviral therapy (ART) offers a powerful intervention in HIV but effectiveness can be compromised by inadequate adherence. This paper is a detailed examination of the experience of medication in a purposively selected group of people living with HIV. In-depth interviews were conducted with 10 HIV positive, West African women of black heritage living in London, UK. This group was of interest since it is the second largest group affected by HIV in the UK. Interviews were subjected to interpretative phenomenological analysis, an idiographic, experiential, qualitative approach. The paper details the women's negative experience of treatment. ART can be considered difficult and unrelenting and may be disconnected from the women's sense of health or illness. Participants' social context often exacerbated the difficulties. Some reported an improvement in their feelings about the medication over time. These findings point to some intrinsic and social motivators which could act as spurs to adherence.

  4. Effect of dietary monensin inclusion on performance, nutrient utilisation, rumen volatile fatty acid concentration and blood status of West African dwarf bucks fed with basal diets of forages.

    PubMed

    Aderinboye, Ronke Yemisi; Onwuka, Chryss Friday Ijeoma; Arigbede, Oluwasanmi Moses; Oduguwa, Oluseyi Olutosin; Aina, Ayobami Bukola Joseph

    2012-06-01

    This experiment investigated the effect of dietary monensin on performance, nutrient utilisation, rumen volatile fatty acid and blood status in West African dwarf (WAD) goats fed with basal diets of forages. Four concentrate supplements were formulated to include 0 (MO), 15 (M15), 30 (M30) and 45 (M45) mg monensin/kg dry matter. Twenty-four WAD bucks (7.3 ± 1.20 kg initial body weight, aged 9-12 months) were randomly allotted to four experimental diets in a completely randomised design for 90 days, six animals per diet. Results indicated that animals fed M15, M30 and M45 diets had lower (P < 0.01) dry matter and water intake than those fed M0 diet. Crude protein and neutral detergent fibre intakes by the bucks followed similar trend. Animals on M15, M30 and M45 had better (P < 0.001) feed and protein efficiency ratio than those fed M0 diet. Rumen pH and total volatile fatty acid concentration were maintained (P > 0.05) while monensin decreased (P < 0.001) acetate/propionate ratio. Blood glucose increased (P < 0.001) from 59.1 mg/dl in animals on M0 diet to 67.8, 66.0 and 66.3 mg/dl in animals on M15, M30 and M45 diets. Overall, there were no variations among animals on M15, M30 and M45 diets. It is concluded that feeding monensin at 15 to 45 mg/kg DM of supplemental concentrate diets to West African dwarf bucks could be effective in improving feed and protein efficiency, manipulating the rumen for increased propionate production and increasing blood glucose levels.

  5. Intense hurricane activity over the past 5,000 years controlled by El Niño and the West African monsoon.

    PubMed

    Donnelly, Jeffrey P; Woodruff, Jonathan D

    2007-05-24

    The processes that control the formation, intensity and track of hurricanes are poorly understood. It has been proposed that an increase in sea surface temperatures caused by anthropogenic climate change has led to an increase in the frequency of intense tropical cyclones, but this proposal has been challenged on the basis that the instrumental record is too short and unreliable to reveal trends in intense tropical cyclone activity. Storm-induced deposits preserved in the sediments of coastal lagoons offer the opportunity to study the links between climatic conditions and hurricane activity on longer timescales, because they provide centennial- to millennial-scale records of past hurricane landfalls. Here we present a record of intense hurricane activity in the western North Atlantic Ocean over the past 5,000 years based on sediment cores from a Caribbean lagoon that contain coarse-grained deposits associated with intense hurricane landfalls. The record indicates that the frequency of intense hurricane landfalls has varied on centennial to millennial scales over this interval. Comparison of the sediment record with palaeo-climate records indicates that this variability was probably modulated by atmospheric dynamics associated with variations in the El Niño/Southern Oscillation and the strength of the West African monsoon, and suggests that sea surface temperatures as high as at present are not necessary to support intervals of frequent intense hurricanes. To accurately predict changes in intense hurricane activity, it is therefore important to understand how the El Niño/Southern Oscillation and the West African monsoon will respond to future climate change.

  6. Significant impacts of radiation physics in the Weather Research and Forecasting model on the precipitation and dynamics of the West African Monsoon

    NASA Astrophysics Data System (ADS)

    Li, R.; Jin, J.; Wang, S.-Y.; Gillies, R. R.

    2015-03-01

    Precipitation from the West African Monsoon (WAM) provides food security and supports the economy in the region. As a consequence of the intrinsic complexities of the WAM's evolution, accurate simulations of the WAM and its precipitation regime, through the application of regional climate models, are challenging. We used the coupled Weather Research and Forecasting (WRF) and Community Land Model (CLM) to explore impacts of radiation physics on the precipitation and dynamics of the WAM. Our results indicate that the radiation physics schemes not only produce biases in radiation fluxes impacting radiative forcing, but more importantly, result in large bias in precipitation of the WAM. Furthermore, the different radiation schemes led to variations in the meridional gradient of surface temperature between the north that is the Sahara desert and the south Guinean coastline. Climate diagnostics indicated that the changes in the meridional gradient of surface temperature affect the position and strength of the African Easterly Jet as well as the low-level monsoonal inflow from the Gulf of Guinea. The net result was that each radiation scheme produced differences in the WAM precipitation regime both spatially and in intensity. Such considerable variances in the WAM precipitation regime and dynamics, resulting from radiation representations, likely have strong feedbacks within the climate system and so have inferences when it comes to aspects of predicted climate change both for the region and globally.

  7. Linking the sub-Saharan and West Eurasian gene pools: maternal and paternal heritage of the Tuareg nomads from the African Sahel

    PubMed Central

    Pereira, Luísa; Černý, Viktor; Cerezo, María; Silva, Nuno M; Hájek, Martin; Vašíková, Alžběta; Kujanová, Martina; Brdička, Radim; Salas, Antonio

    2010-01-01

    The Tuareg presently live in the Sahara and the Sahel. Their ancestors are commonly believed to be the Garamantes of the Libyan Fezzan, ever since it was suggested by authors of antiquity. Biological evidence, based on classical genetic markers, however, indicates kinship with the Beja of Eastern Sudan. Our study of mitochondrial DNA (mtDNA) sequences and Y chromosome SNPs of three different southern Tuareg groups from Mali, Burkina Faso and the Republic of Niger reveals a West Eurasian-North African composition of their gene pool. The data show that certain genetic lineages could not have been introduced into this population earlier than ∼9000 years ago whereas local expansions establish a minimal date at around 3000 years ago. Some of the mtDNA haplogroups observed in the Tuareg population were involved in the post-Last Glacial Maximum human expansion from Iberian refugia towards both Europe and North Africa. Interestingly, no Near Eastern mtDNA lineages connected with the Neolithic expansion have been observed in our population sample. On the other hand, the Y chromosome SNPs data show that the paternal lineages can very probably be traced to the Near Eastern Neolithic demic expansion towards North Africa, a period that is otherwise concordant with the above-mentioned mtDNA expansion. The time frame for the migration of the Tuareg towards the African Sahel belt overlaps that of early Holocene climatic changes across the Sahara (from the optimal greening ∼10 000 YBP to the extant aridity beginning at ∼6000 YBP) and the migrations of other African nomadic peoples in the area. PMID:20234393

  8. Adapting the Andersen model to a francophone West African immigrant population: hepatitis B screening and linkage to care in New York City.

    PubMed

    Blanas, Demetri A; Nichols, Kim; Bekele, Mulusew; Shankar, Hari; Bekele, Saba; Jandorf, Lina; Izzeldin, Saria; Ndiaye, Daouda; Traore, Adama; Bassam, Motahar; Perumalswami, Ponni V

    2015-02-01

    Hepatitis B virus (HBV) is highly endemic in West Africa and immigration from this region to the United States has greatly increased over the past quarter century. Using the Andersen Model as a conceptual framework, this study qualitatively examines francophone West African immigrants' perceptions of factors affecting access to HBV screening and linkage-to-care in New York City. Four focus groups were conducted with 39 purposefully selected participants. The focus groups were conducted in French, audio-recorded, translated into English, transcribed, analyzed, and coded for major themes. Participants identified increasing knowledge of HBV and opportunities to access care in a culturally-sensitive manner that decreases fatalism and avoids generating stigma as priorities. They also emphasized the importance of engaging religious establishments and social networks and employing the Internet to disseminate HBV-relevant information. Cost and health insurance are identified as future challenges that will need to be addressed in a health care environment in which undocumented immigrants are ineligible for health insurance. The qualitative analysis in this study highlights the recursive and interdependent nature of the Andersen Model, and a modification of the model is proposed that is intended to inform examinations of other minority communities' access to health care.

  9. A Critical Review of the West African School Certificate Examination Syllabus in History as Taught in Western Nigeria Grammar Schools

    ERIC Educational Resources Information Center

    Adejunmobi, S. A.

    1974-01-01

    The author compares syllabus outlines for the 5-year grammar school course (Grades 8-12 equivalent) in West Africa, Nigeria, the United Kingdom, and the United States, and concludes that a national directive on history syllabus similar to that of Britain and the U.S. is needed including aims of history teaching in Nigeria. (JT)

  10. Lack of specific alleles for the bovine chemokine (C-X-C) receptor type 4 (CXCR4) gene in West African cattle questions its role as a candidate for trypanotolerance.

    PubMed

    Álvarez, Isabel; Pérez-Pardal, Lucía; Traoré, Amadou; Fernández, Iván; Goyache, Félix

    2016-08-01

    A panel of 81 Asian, African and European cattle (Bos taurus and B. indicus) was analysed for the whole sequence of the CXCR4 gene (3844bp), a strong candidate for cattle trypanotolerance. Thirty-one polymorphic sites identified gave 31 different haplotypes. Neutrality tests rejected the hypothesis of either positive or purifying selection. Bayesian phylogenetic tree showed differentiation of haplotypes into two clades gathering genetic variability predating domestication. Related with clades definition, linkage disequilibrium analyses suggested the existence of one only linkage block on the CXCR4 gene. Two tag SNPs identified on exon 2 captured 50% of variability. Whatever the analysis carried out, no clear separation between cattle groups was identified. Most haplotypes identified in West African taurine cattle were also found in European cattle and in Asian and West African zebu. West African taurine samples did not carry unique variants on the CXCR4 gene sequence. The current analysis failed in identifying a causal mutation on the CXCR4 gene underlying a previously reported QTL for cattle trypanotolerance on BTA2. PMID:27117936

  11. The Paternal Landscape along the Bight of Benin – Testing Regional Representativeness of West-African Population Samples Using Y-Chromosomal Markers

    PubMed Central

    Larmuseau, Maarten H. D.; Vessi, Andrea; Jobling, Mark A.; Van Geystelen, Anneleen; Primativo, Giuseppina; Biondi, Gianfranco; Martínez-Labarga, Cristina; Ottoni, Claudio; Decorte, Ronny; Rickards, Olga

    2015-01-01

    Patterns of genetic variation in human populations across the African continent are still not well studied in comparison with Eurasia and America, despite the high genetic and cultural diversity among African populations. In population and forensic genetic studies a single sample is often used to represent a complete African region. In such a scenario, inappropriate sampling strategies and/or the use of local, isolated populations may bias interpretations and pose questions of representativeness at a macrogeographic-scale. The non-recombining region of the Y-chromosome (NRY) has great potential to reveal the regional representation of a sample due to its powerful phylogeographic information content. An area poorly characterized for Y-chromosomal data is the West-African region along the Bight of Benin, despite its important history in the trans-Atlantic slave trade and its large number of ethnic groups, languages and lifestyles. In this study, Y-chromosomal haplotypes from four Beninese populations were determined and a global meta-analysis with available Y-SNP and Y-STR data from populations along the Bight of Benin and surrounding areas was performed. A thorough methodology was developed allowing comparison of population samples using Y-chromosomal lineage data based on different Y-SNP panels and phylogenies. Geographic proximity turned out to be the best predictor of genetic affinity between populations along the Bight of Benin. Nevertheless, based on Y-chromosomal data from the literature two population samples differed strongly from others from the same or neighbouring areas and are not regionally representative within large-scale studies. Furthermore, the analysis of the HapMap sample YRI of a Yoruban population from South-western Nigeria based on Y-SNPs and Y-STR data showed for the first time its regional representativeness, a result which is important for standard population and forensic genetic applications using the YRI sample. Therefore, the uniquely

  12. Timing the structural events in the Palaeoproterozoic Bolé-Nangodi belt terrane and adjacent Maluwe basin, West African craton, in central-west Ghana

    NASA Astrophysics Data System (ADS)

    de Kock, G. S.; Théveniaut, H.; Botha, P. M. W.; Gyapong, W.

    2012-04-01

    deposited concordantly on the submerged Sunyani strata after a hiatus of 20 million years. After cessation of the NW-SE-directed compression the early Tanina Suite intruded as batholiths, dykes and sheets and produced garnet, staurolite, sillimanite and kyanite in their thermal aureoles. Docking of the Sunyani basin produced the DE2 thrust related folding and stacking in the deformed and granitoid invaded Maluwe basin as well as the single stage sin- and anticlinoria in the Sunyani and Banda Groups. In the Maluwe basin the Abulembire fragment acted as a resistor and the approaching front rotated anticlockwise and clockwise around the barrier to form west- and north-directed piggy-back thrust-stacking and deformation of the Tanina Suite granitoids. Due to the low metamorphic conditions the DE2 fabric is limited to crenulation cleavages in the more psammitic and pelitic units. The fold axes are double plunging (N-S and E-W) up to 60° with the axial planar fabric subvertical. Post-D2 tectonic relaxation has allowed the emplacement of the last Tanina Suite calc-alkaline melts and was succeeded by N-S extension fracturing (DE3) along which mantle derived Wakawaka gabbroids and syenite intruded. The DE1 folding occurred between 2125 and 2122 Ma and DE2 before 2119 Ma. The tectonic relaxation occurred at 2118 Ma. Around 2100 Ma, NE-SW directed strike-slip shearing (DE4), fractured the Bolé-Nangodi terrane and enhanced the basin-belt boundary. Along the boundary, the displacement was dextral along vertical faults but, southward, it became more east-over-west thrust related. Associated tension gashes are filled with vein quartz and pegmatite and typical of the brittle sector of the crust. Tectonism in this part of the intraoceanic accretionary arc back-arc complex was concluded by limited, right-lateral strike-slip (DE5) movement which formed some breccias.

  13. Inter-annual Tropospheric Aerosol Variability in Late Twentieth Century and its Impact on Tropical Atlantic and West African Climate by Direct and Semi-direct Effects

    SciTech Connect

    Evans, Katherine J; Hack, James J; Truesdale, John; Mahajan, Salil; Lamarque, J-F

    2012-01-01

    A new high-resolution (0.9$^{\\circ}$x1.25$^{\\circ}$ in the horizontal) global tropospheric aerosol dataset with monthly resolution is generated using the finite-volume configuration of Community Atmosphere Model (CAM4) coupled to a bulk aerosol model and forced with recent estimates of surface emissions for the latter part of twentieth century. The surface emissions dataset is constructed from Coupled Model Inter-comparison Project (CMIP5) decadal-resolution surface emissions dataset to include REanalysis of TROpospheric chemical composition (RETRO) wildfire monthly emissions dataset. Experiments forced with the new tropospheric aerosol dataset and conducted using the spectral configuration of CAM4 with a T85 truncation (1.4$^{\\circ}$x1.4$^{\\circ}$) with prescribed twentieth century observed sea surface temperature, sea-ice and greenhouse gases reveal that variations in tropospheric aerosol levels can induce significant regional climate variability on the inter-annual timescales. Regression analyses over tropical Atlantic and Africa reveal that increasing dust aerosols can cool the North African landmass and shift convection southwards from West Africa into the Gulf of Guinea in the spring season in the simulations. Further, we find that increasing carbonaceous aerosols emanating from the southwestern African savannas can cool the region significantly and increase the marine stratocumulus cloud cover over the southeast tropical Atlantic ocean by aerosol-induced diabatic heating of the free troposphere above the low clouds. Experiments conducted with CAM4 coupled to a slab ocean model suggest that present day aerosols can shift the ITCZ southwards over the tropical Atlantic and can reduce the ocean mixed layer temperature beneath the increased marine stratocumulus clouds in the southeastern tropical Atlantic.

  14. Statistical Modeling of the Abundance of Vectors of West African Rift Valley Fever in Barkédji, Senegal

    PubMed Central

    Talla, Cheikh; Diallo, Diawo; Dia, Ibrahima; Ba, Yamar; Ndione, Jacques-André; Sall, Amadou Alpha; Morse, Andy; Diop, Aliou; Diallo, Mawlouth

    2014-01-01

    Rift Valley fever is an emerging mosquito-borne disease that represents a threat to human and animal health. The exophilic and exophagic behavior of the two main vector in West Africa (Aedes vexans and Culex poicilipes), adverse events post-vaccination, and lack of treatment, render ineffective the disease control. Therefore it is essential to develop an information system that facilitates decision-making and the implementation of adaptation strategies. In East Africa, RVF outbreaks are linked with abnormally high rainfall, and can be predicted up to 5 months in advance by modeling approaches using climatic and environmental parameters. However, the application of these models in West Africa remains unsatisfactory due to a lack of data for animal and human cases and differences in the dynamics of the disease emergence and the vector species involved in transmission. Models have been proposed for West Africa but they were restricted to rainfall impact analysis without a spatial dimension. In this study, we developed a mixed Bayesian statistical model to evaluate the effects of climatic and ecological determinants on the spatiotemporal dynamics of the two main vectors. Adult mosquito abundance data were generated from July to December every fortnight in 2005–2006 at 79 sites, including temporary ponds, bare soils, shrubby savannah, wooded savannah, steppes, and villages in the Barkédji area. The results demonstrate the importance of environmental factors and weather conditions for predicting mosquito abundance. The rainfall and minimum temperature were positively correlated with the abundance of Cx. poicilipes, whereas the maximum temperature had negative effects. The rainfall was negatively correlated with the abundance of Ae. vexans. After combining land cover classes, weather conditions, and vector abundance, our model was used to predict the areas and periods with the highest risks of vector pressure. This information could support decision-making to improve

  15. Mitigation of Disasters Due to Severe Climate Events: from Policy to Practice,the West African Coastal Region Experience

    NASA Astrophysics Data System (ADS)

    Ediang, Okuku

    2016-07-01

    The distributive pattern of disaster due to severe climate events over the coast of West Africa especially Nigeria was examined using yearly mean disaster due to severe climatic events for the period of 30 years (1981-2010) from the marine stations in the coastal region of Nigeria. Graphical and isohyetal analyses were used to look into the patter of severe weather events over the area considered and to see if the severe weather events is increasing or not in the coast of West Africa especially the Nigerian coast and how to mitigate ,were policy relating to severe weather events are discussed. The paper conclude that due to the nature of coast of West Africa and Nigeria in particular, it enjoys longer severe weather events season than dry during the wet season, it is common to observe periods of enhanced or suppressed convective activity to persist over the wide areas for somedays. This paper also contributes to the wealth of knowledge already existing on Indigenous people play major roles in preserving the ecosystem especially during severe weather events . This has resulted in the recent calls for the integration of indigenous knowledge systems into global knowledge system strategies. Until now, integrating local knowledge systems into severe weather events and climate change concerns is not a completely new idea. A comprehensive review of literature using electronic and non-electronic databases formed the methodology. The paper conclude also by drawing the attention that by targeting Promoting indigenous people's participation in severe weather events and climate change issues is an important initiative towards adaptation and sustainable development in Africa and around the world. It is increasingly realized that the global knowledge system has dominated research, policies and programmes that address current severe weather events and climate change's challenges,mitigation and adaptation strategies.

  16. Statistical modeling of the abundance of vectors of West African Rift Valley fever in Barkédji, Senegal.

    PubMed

    Talla, Cheikh; Diallo, Diawo; Dia, Ibrahima; Ba, Yamar; Ndione, Jacques-André; Sall, Amadou Alpha; Morse, Andy; Diop, Aliou; Diallo, Mawlouth

    2014-01-01

    Rift Valley fever is an emerging mosquito-borne disease that represents a threat to human and animal health. The exophilic and exophagic behavior of the two main vector in West Africa (Aedes vexans and Culex poicilipes), adverse events post-vaccination, and lack of treatment, render ineffective the disease control. Therefore it is essential to develop an information system that facilitates decision-making and the implementation of adaptation strategies. In East Africa, RVF outbreaks are linked with abnormally high rainfall, and can be predicted up to 5 months in advance by modeling approaches using climatic and environmental parameters. However, the application of these models in West Africa remains unsatisfactory due to a lack of data for animal and human cases and differences in the dynamics of the disease emergence and the vector species involved in transmission. Models have been proposed for West Africa but they were restricted to rainfall impact analysis without a spatial dimension. In this study, we developed a mixed Bayesian statistical model to evaluate the effects of climatic and ecological determinants on the spatiotemporal dynamics of the two main vectors. Adult mosquito abundance data were generated from July to December every fortnight in 2005-2006 at 79 sites, including temporary ponds, bare soils, shrubby savannah, wooded savannah, steppes, and villages in the Barkédji area. The results demonstrate the importance of environmental factors and weather conditions for predicting mosquito abundance. The rainfall and minimum temperature were positively correlated with the abundance of Cx. poicilipes, whereas the maximum temperature had negative effects. The rainfall was negatively correlated with the abundance of Ae. vexans. After combining land cover classes, weather conditions, and vector abundance, our model was used to predict the areas and periods with the highest risks of vector pressure. This information could support decision-making to improve RVF

  17. Polymorphism of the human factor H-related gene (FHR-1) and of factor H in a West African individual

    SciTech Connect

    Meyer, C.G.; Skerka, C.; Zipfel, P.F.

    1995-03-01

    The human factor H-related 1 (FHR-1) protein is structurally and immunogenically related to the regulatory complement protein factor H (FH). Polymorphism of the FHR-1 gene is indicated by the nucleotide differences as described by the five cDNA clones isolated so far. In order to further analyze this polymorphism we identified PCR-primers which allow the simultaneous amplification of FHR-1 and FH alleles in a single polymerase chain reaction (PCR). By DNA sequence analysis, two novel FHR-1 variants and one as yet unrecognized FH allele could be characterized in an individual from Benin, West Africa. 2 refs., 1 fig.

  18. Have abrupt climate variations of the last glacial possibly been muted in the south-west African tropics by counteracting mechanisms?

    NASA Astrophysics Data System (ADS)

    Hessler, I.; Dupont, L.; Handiani, D.; Steinke, S.; Groeneveld, J.; Merkel, U.; Paul, A.

    2012-04-01

    The last glacial period including the last deglaciation (73.5-10 ka BP) is characterised by abrupt shifts between extreme climatic conditions. Millennial-scale climate variations associated with North Atlantic Heinrich Stadials (HSs) are thought to be transmitted by both the atmospheric and oceanic circulation resulting in a near-global footprint. It is further thought that HSs are closely related to a reduction or shut-down of the Atlantic Meridional Overturning Circulation, which, according to the bipolar-seesaw hypothesis, leads to the accumulation of heat in the South Atlantic. In addition, it is hypothesised that HSs result in a southward shift of the Intertropical Convergence Zone which then would likely influence the vegetation composition in the African tropics. To investigate the impact of HSs on the terrestrial African realm and the south-east Atlantic we reconstructed the vegetation development in Angola and the southern Congo Basin as well as the sea surface temperatures (SST) of the south-east Atlantic using marine sediments of ODP Site 1078 (11° 55'S, 13° 24'E, 427 m water depth). Two species of planktonic foraminifera were selected to reconstruct variations in surface water conditions in the south-east Atlantic. Due the ecological and seasonal preferences of Globigerinoides ruber (pink) this species provides a good tool to estimate SST variations during the southern hemisphere summer. In contrast, Globigerina bulloides is representing the Benguela Upwelling System during the southern hemisphere winter. While Mg/Ca-based SSTs of G. ruber (pink) were significantly higher by 1° -2° C during periods of abrupt climate change, the impact of HSs during southern hemisphere winter is less obvious. However, although there are several vegetation records that show an impact of HSs in the African tropics, our high-resolution pollen record from ODP Site 1078 reflects no vegetation changes during periods of HSs. Model simulations conducted with an Earth System

  19. Land use scenarios development and impacts assessment on vegetation carbon/nitrogen sequestration in the West African Sudan savanna watershed, Benin

    NASA Astrophysics Data System (ADS)

    Chabi, A.

    2015-12-01

    AbstractBackground: Reduced Emissions from Deforestation and Degradation (REDD+), being developed through the United Nations Framework Convention on Climate Change (UNFCCC) requires information on the carbon/nitrogen stocks in the plant biomass for predicting future climate under scenarios development. The development of land use scenarios in West Africa is needed to predict future impacts of change in the environment and the socio-economic status of rural communities. The study aims at developing land use scenario based on mitigation strategy to climate change as an issue of contributing for carbon and nitrogen sequestration, the condition 'food focused' as a scenario based crop production and 'financial investment' as scenario based on an economic development pathway, and to explore the possible future temporal and spatial impacts on vegetation carbon/nitrogen sequestration/emission and socio-economic status of rural communities. Preliminary results: BEN-LUDAS (Benin-Land Use DyNamic Simulator) model, carbon and nitrogen equations, remote sensing and socio-economic data were used to predict the future impacts of each scenario in the environment and human systems. The preliminary results which are under analysis will be presented soon. Conclusion: The proposed BEN-LUDAS models will help to contribute to policy decision making at the local and regional scale and to predict future impacts of change in the environment and socio-economic status of the rural communities. Keywords: Land use scenarios development, BEN-LUDAS, socio-economic status of rural communities, future impacts of change, assessment, West African Sudan savanna watershed, Benin

  20. Land use scenarios development and impacts assessment on vegetation carbon/nitrogen sequestration in the West African Sudan savanna watershed, Benin

    NASA Astrophysics Data System (ADS)

    Chabi, A.

    2015-12-01

    ackground: Reduced Emissions from Deforestation and Degradation (REDD+), being developed through the United Nations Framework Convention on Climate Change (UNFCCC) requires information on the carbon/nitrogen stocks in the plant biomass for predicting future climate under scenarios development. The development of land use scenarios in West Africa is needed to predict future impacts of change in the environment and the socio-economic status of rural communities. The study aims at developing land use scenario based on mitigation strategy to climate change as an issue of contributing for carbon and nitrogen sequestration, the condition 'food focused' as a scenario based crop production and 'financial investment' as scenario based on an economic development pathway, and to explore the possible future temporal and spatial impacts on vegetation carbon/nitrogen sequestration/emission and socio-economic status of rural communities. Preliminary results: BEN-LUDAS (Benin-Land Use DyNamic Simulator) model, carbon and nitrogen equations, remote sensing and socio-economic data were used to predict the future impacts of each scenario in the environment and human systems. The preliminary results which are under analysis will be presented soon. Conclusion: The proposed BEN-LUDAS models will help to contribute to policy decision making at the local and regional scale and to predict future impacts of change in the environment and socio-economic status of the rural communities. Keywords: Land use scenarios development, BEN-LUDAS, socio-economic status of rural communities, future impacts of change, assessment, West African Sudan savanna watershed, Benin

  1. Genetic characterization of new West African simian immunodeficiency virus SIVsm: geographic clustering of household-derived SIV strains with human immunodeficiency virus type 2 subtypes and genetically diverse viruses from a single feral sooty mangabey troop.

    PubMed Central

    Chen, Z; Telfier, P; Gettie, A; Reed, P; Zhang, L; Ho, D D; Marx, P A

    1996-01-01

    It has been proposed that human immunodeficiency virus type 2 (HIV-2) originated from simian immunodeficiency viruses (SIVs) that are natural infections of sooty mangabeys (Cercocebus torquatus atys). To test this hypothesis, SIVs from eight sooty mangabeys, including six new viruses from West Africa, were genetically characterized. gag and env sequences showed that while the viruses of all eight sooty mangabeys belonged to the SIVsm/HIV-2 family, each was widely divergent from SIVs found earlier in captive monkeys at American primate centers. In two SIVs from sooty mangabeys discovered about 100 miles (ca. 161 Km) from each other in rural West Africa, the amino acids of a conserved gag p17-p26 region differed by 19.3%, a divergence greater than that in four of five clades of HIV-2 and in SIVs found in other African monkey species. Analysis of gag region sequences showed that feral mangabeys in one small troop harbored four distinct SIVs. Three of the newly found viruses were genetically divergent, showing as much genetic distance from each other as from the entire SIVsm/HIV-2 family. Sequencing and heteroduplex analysis of one feral animal-derived SIV showed a mosaic genome containing an env gene that was homologous with other feral SIVsm env genes in the troop but having a gag gene from another, distinct SIV. Surprisingly a gag phylogenetic tree based on nucleotide sequences showed that the African relatives closest to all three household-derived SIVs were HIV-2 subtypes D and E from humans in the same West African areas. In one case, the SIV/HIV-2 cluster was from the same village. The findings support the hypothesis that each HIV-2 subtype in West Africans originated from widely divergent SIVsm strains, transmitted by independent cross-species events in the same geographic locations. PMID:8648696

  2. Rainfall monitoring based on microwave links from cellular telecommunication networks: First results from a West African test bed

    NASA Astrophysics Data System (ADS)

    Doumounia, Ali; Gosset, Marielle; Cazenave, Frederic; Kacou, Modeste; Zougmore, François

    2014-08-01

    Rainfall monitoring based on commercial terrestrial microwave links is tested for the first time in Burkina Faso, in Sahelian West Africa. In collaboration with one national cellular phone operator, Telecel Faso, the attenuation on a 29 km long microwave link operating at 7 GHz was monitored at 1 s time rate for the monsoon season 2012. The time series of attenuation is transformed into rain rates and compared with rain gauge data. The method is successful in quantifying rainfall: 95% of the rainy days are detected. The correlation with the daily rain gauge series is 0.8, and the season bias is 6%. The correlation at the 5 min time step within each event is also high. These results demonstrate the potential interest of exploiting national and regional wireless telecommunication networks for monitoring rainfall in Africa, where operational rain gauge networks are degrading and the hydrometeorological risk increasing.

  3. Cloud properties during active and break spells of the West African summer monsoon from CloudSat-CALIPSO measurements

    NASA Astrophysics Data System (ADS)

    Efon, E.; Lenouo, A.; Monkam, D.; Manatsa, D.

    2016-07-01

    High resolution of daily rainfall dataset from the Tropical Rainfall Measuring Mission (TRMM) was used to identify active and break cloud formation periods. The clouds were characterized based on CloudSat-CALIPSO satellite images over West Africa during the summer monsoon during the period 2006-2010. The active and break periods are defined as the periods during the peak monsoon months of June to August when the normalized anomaly of rainfall over the monsoon core zone is greater than 0.9 or less than -0.9 respectively, provided the criteria is satisfied for at least three consecutive days. It is found that about 90% of the break period and 66.7% of the active spells lasted 3-4 days. Active spells lasting duration of about a week were observed while no break spell had such a long span. Cloud macrophysical (cloud base height (CBH), cloud top height (CTH) and cloud geometric depth (∆H), microphysical (cloud liquid water content, (LWC), liquid number concentration (LNC), liquid effective radius, ice water content (IWC), ice number concentration (INC) and ice effective radius) and radiative (heating rate properties) over South Central West Africa (5-15°N; 15°W-10°E) during the active and break spells were also analyzed. High-level clouds are more predominant during the break periods compared to the active periods. Active spells have lower INC compared to the break spells. Liquid water clouds are observed to have more radiative forcing during the active than break periods while ice phase clouds bring more cooling effect during the break spells compared to the active spells.

  4. The Relationship between Aerosol Composition and Concentration and Visual Range on Barbados, West Indies: The Impact of African Dust

    NASA Astrophysics Data System (ADS)

    Huang, J.; Prospero, J.; Zhang, C.; Arimoto, R.

    2006-12-01

    Visual Range (VR) measured at Grantley Adams Airport on Barbados shows a very strong annual cycle with the minimum VR values occurring in June or July. This cycle closely matches the annual cycle of African dust concentrations measured in the trade winds at Barbados (13°15'N, 59°30'W) where observations first began in 1965. In winter, monthly mean VR was typically around 30 km or greater while in summer it frequently dipped below 20 km. This same clear signal is observed in the VR records from near-by islands where the same seasonal cycle of dust would be expected: St. Lucia, Martinique and Trinidad and Tobago. We examined the relationship between VR on Barbados and the concentrations of the three major aerosol constituents that we would expect to have the strongest influence on VR: mineral dust, sea salt, and non-sea- salt sulfate (nss-SO4^{=}). We used VR data for the period from 1973, when measurements first began, up to 2006. We found a large discrepancy between the observed VR at the airport and the VR derived from the Koschmieder equation using literature values for the optical properties of the aerosol components; this simple approach would require a much smaller constant than the commonly-used value, 3.912. We further explored the effects of particle size distribution and relative humidity. During boreal summer when VR is lowest, dust is the dominant supramicron aerosol component and it clearly is the major factor in controlling VR. Nonetheless the submicron fraction also has a comparable impact due to its significantly higher light scattering efficiency. During winter, when there is little or no dust, sea salt aerosol and sulfate are dominant. In this report we focus on the various factors that affect visibility on Barbados especially the role of aerosols dominated by supramicrometer particles. We also consider the effects of other factors such as wind speed and precipitation. Finally, we note that the close relationship between summertime VR and dust

  5. Genetics, Morphology, Advertisement Calls, and Historical Records Distinguish Six New Polyploid Species of African Clawed Frog (Xenopus, Pipidae) from West and Central Africa.

    PubMed

    Evans, Ben J; Carter, Timothy F; Greenbaum, Eli; Gvoždík, Václav; Kelley, Darcy B; McLaughlin, Patrick J; Pauwels, Olivier S G; Portik, Daniel M; Stanley, Edward L; Tinsley, Richard C; Tobias, Martha L; Blackburn, David C

    2015-01-01

    African clawed frogs, genus Xenopus, are extraordinary among vertebrates in the diversity of their polyploid species and the high number of independent polyploidization events that occurred during their diversification. Here we update current understanding of the evolutionary history of this group and describe six new species from west and central sub-Saharan Africa, including four tetraploids and two dodecaploids. We provide information on molecular variation, morphology, karyotypes, vocalizations, and estimated geographic ranges, which support the distinctiveness of these new species. We resurrect Xenopus calcaratus from synonymy of Xenopus tropicalis and refer populations from Bioko Island and coastal Cameroon (near Mt. Cameroon) to this species. To facilitate comparisons to the new species, we also provide comments on the type specimens, morphology, and distributions of X. epitropicalis, X. tropicalis, and X. fraseri. This includes significantly restricted application of the names X. fraseri and X. epitropicalis, the first of which we argue is known definitively only from type specimens and possibly one other specimen. Inferring the evolutionary histories of these new species allows refinement of species groups within Xenopus and leads to our recognition of two subgenera (Xenopus and Silurana) and three species groups within the subgenus Xenopus (amieti, laevis, and muelleri species groups). PMID:26672747

  6. Lithostratigraphic framework and correlation of the Neoproterozoic northern West African Craton passive margin sequence (Siroua-Zenaga-Bouazzer Elgraara Inliers, Central Anti-Atlas, Morocco): an integrated approach

    NASA Astrophysics Data System (ADS)

    Bouougri, El Hafid; Saquaque, Ali

    2004-06-01

    The Neoproterozoic volcano-sedimentary cover (˜0.8 Ga) deposited on the northern passive margin of the West African craton occurs in the central Anti-Atlas inliers and is a ˜2 km thick succession formally termed the Tizi n-Taghatine Group. The group comprises two sedimentary packages (lower and upper) separated by a middle volcanic unit. An integrated approach of lithostratigraphy, sedimentology, sequence stratigraphy and paleogeographic setting have been combined to provide well constrained correlation and lithostratigraphic organization. The Tizi n-Taghatine Group is formally subdivided into 12 Formations, 10 of which are defined in the lower sedimentary package while the middle volcanic unit and the upper sedimentary package constitute the two uppermost Formations. The lithostratigraphic organization and subdivision of the Tizi n-Taghatine Group constitutes a stratigraphic record of major paleogeographic settings and large cyclic changes in depositional system due to relative sea-level variations. The integrated approach of combination and comparison of various data provides significant information on the nature, origin and time significance of the formal unit boundaries. This leads to proposing a correlative scheme for the Tizi n-Taghatine Group across the Neoproterozoic central Anti-Atlas suture zone.

  7. Genetics, Morphology, Advertisement Calls, and Historical Records Distinguish Six New Polyploid Species of African Clawed Frog (Xenopus, Pipidae) from West and Central Africa

    PubMed Central

    Evans, Ben J.; Carter, Timothy F.; Greenbaum, Eli; Gvoždík, Václav; Kelley, Darcy B.; McLaughlin, Patrick J.; Pauwels, Olivier S. G.; Portik, Daniel M.; Stanley, Edward L.; Tinsley, Richard C.; Tobias, Martha L.; Blackburn, David C.

    2015-01-01

    African clawed frogs, genus Xenopus, are extraordinary among vertebrates in the diversity of their polyploid species and the high number of independent polyploidization events that occurred during their diversification. Here we update current understanding of the evolutionary history of this group and describe six new species from west and central sub-Saharan Africa, including four tetraploids and two dodecaploids. We provide information on molecular variation, morphology, karyotypes, vocalizations, and estimated geographic ranges, which support the distinctiveness of these new species. We resurrect Xenopus calcaratus from synonymy of Xenopus tropicalis and refer populations from Bioko Island and coastal Cameroon (near Mt. Cameroon) to this species. To facilitate comparisons to the new species, we also provide comments on the type specimens, morphology, and distributions of X. epitropicalis, X. tropicalis, and X. fraseri. This includes significantly restricted application of the names X. fraseri and X. epitropicalis, the first of which we argue is known definitively only from type specimens and possibly one other specimen. Inferring the evolutionary histories of these new species allows refinement of species groups within Xenopus and leads to our recognition of two subgenera (Xenopus and Silurana) and three species groups within the subgenus Xenopus (amieti, laevis, and muelleri species groups). PMID:26672747

  8. Land Cover Land Use change and soil organic carbon under climate variability in the semi-arid West African Sahel (1960-2050)

    NASA Astrophysics Data System (ADS)

    Dieye, Amadou M.

    Land Cover Land Use (LCLU) change affects land surface processes recognized to influence climate change at local, national and global levels. Soil organic carbon is a key component for the functioning of agro-ecosystems and has a direct effect on the physical, chemical and biological characteristics of the soil. The capacity to model and project LCLU change is of considerable interest for mitigation and adaptation measures in response to climate change. A combination of remote sensing analyses, qualitative social survey techniques, and biogeochemical modeling was used to study the relationships between climate change, LCLU change and soil organic carbon in the semi-arid rural zone of Senegal between 1960 and 2050. For this purpose, four research hypotheses were addressed. This research aims to contribute to an understanding of future land cover land use change in the semi-arid West African Sahel with respect to climate variability and human activities. Its findings may provide insights to enable policy makers at local to national levels to formulate environmentally and economically adapted policy decisions. This dissertation research has to date resulted in two published and one submitted paper.

  9. Effects of three novel metalloproteinases from the venom of the West African saw-scaled viper, Echis ocellatus on blood coagulation and platelets.

    PubMed

    Howes, J-M; Kamiguti, A S; Theakston, R D G; Wilkinson, M C; Laing, G D

    2005-06-20

    Two metalloproteinases, a 24-kDa P-I EoVMP1 and a 56-kDa P-III EoVMP2, have recently been isolated from the venom of the West African saw-scaled viper Echis ocellatus. We now reveal a new 65-kDa haemorrhagic group P-III metalloproteinase which we have designated EoVMP3. The aim of this study was to determine whether these three snake venom metalloproteinases (SVMPs) affect platelets and blood coagulation. EoVMP1 had no effect on the aggregation of washed human platelets, whereas EoVMP2 inhibited collagen-induced platelet aggregation. In contrast, EoVMP3 did not inhibit the aggregation of platelets by collagen but instead activated platelets in the absence of any additional co-factors. All three SVMPs were capable of activating prothrombin to varying degrees and can therefore be described as procoagulants. EoVMP1, EoVMP2 and EoVMP3 share sequence identity with other members of the reprolysin family, but differ greatly in their effects on some of the components that control haemostasis. PMID:15863354

  10. Effects of species and season on chemical composition and ruminal crude protein and organic matter degradability of some multi-purpose tree species by West African dwarf rams.

    PubMed

    Arigbede, O M; Anele, U Y; Südekum, K-H; Hummel, J; Oni, A O; Olanite, J A; Isah, A O

    2012-04-01

    Seasonal chemical composition and ruminal organic matter (OM) and crude protein (CP) degradabilities were determined in four tropical multi-purpose tree species (MPTS) namely; Pterocarpus santalinoides, Grewia pubescens, Enterolobium cyclocarpum and Leucaena leucocephala. Three West African dwarf (WAD) rams fitted with permanent rumen cannula were used for the degradability trials. Foliage samples were collected four times to represent seasonal variations as follows: January--mid dry; April--late dry; July--mid rainy and October--late rainy seasons. Leaf samples were randomly collected from the trees for estimation of dry matter (DM) and chemical composition. Ruminal in sacco OM and CP degradabilities were estimated from residues in nylon bags. All samples had high CP (161-259 g/kg DM) and moderate fibre concentrations [neutral detergent fibre (without residual ash], 300-501 g/kg DM; acid detergent fibre (without residual ash), 225-409 g/kg DM and acid detergent lignin, 87-179 g/kg DM across seasons. Interaction effects of species and season on chemical composition were highly significant (p = 0.001) except for trypsin inhibitor (p = 0.614). The MPTS recorded more than 60% OM and CP degradability at 24 h, which implied that they were all highly degradable in the rumen. Their incorporation into ruminant feeding systems as dry season forage supplements is therefore recommended.

  11. Genetic Diversity of Mycobacterium africanum Clinical Isolates Based on IS6110-Restriction Fragment Length Polymorphism Analysis, Spoligotyping, and Variable Number of Tandem DNA Repeats

    PubMed Central

    Viana-Niero, Cristina; Gutierrez, Cristina; Sola, Christophe; Filliol, Ingrid; Boulahbal, Fadila; Vincent, Véronique; Rastogi, Nalin

    2001-01-01

    A collection of 105 clinical isolates originally identified as Mycobacterium africanum were characterized using both phenotypic and genotyping methods. The phenotypic methods included routine determination of cultural properties and biochemical tests used to discriminate among the members of the M. tuberculosis complex, whereas genotypic characterization was based on IS6110-restriction fragment length polymorphism (IS6110-RFLP) analysis, IS1081-RFLP analysis, direct repeat-based spacer oligonucleotide typing (spoligotyping), variable number of tandem DNA repeats (VNTR), and the polymorphism of the oxyR, pncA, and mtp40 loci. The results obtained showed that a majority of M. africanum isolates were characterized by a specific spoligotyping pattern that was intermediate between those of M. tuberculosis and M. bovis, which do not hybridize with spacers 33 to 36 and spacers 39 to 43, respectively. A tentative M. africanum-specific spoligotyping signature appeared to be absence of spacers 8, 9, and 39. Based on spoligotyping, as well as the polymorphism of oxyR and pncA, a total of 24 isolates were excluded from the final study (19 were identified as M. tuberculosis, 2 were identified as M. canetti, and 3 were identified as M. bovis). The remaining 81 M. africanum isolates were efficiently subtyped in three distinct subtypes (A1 to A3) by IS6110-RFLP analysis and spoligotyping. The A1 and A2 subgroups were relatively more homogeneous upon spoligotyping than A3. Further analysis of the three subtypes by VNTR corroborated the highly homogeneous nature of the A2 subtype but showed significant variations for subtypes A1 and A3. A phylogenetic tree based on a selection of isolates representing the three subtypes using VNTR and spoligotyping alone or in combination confirmed the subtypes described as well as the heterogeneity of subtype A3. PMID:11136749

  12. PTCH-1 and MDM2 expression in ameloblastoma from a West African sub-population: implication for chemotherapeutics

    PubMed Central

    Udeabor, Samuel Ebele; Adisa, Akinyele Olumuyiwa; Lawal, Ahmed Oluwatoyin; Barbeck, Mike; Booms, Patrick; Sader, Robert Alexander; Ghanaati, Shahram

    2015-01-01

    Introduction Ameloblastoma is a slow growing, painless odontogenic swelling which can attain sizes that result in severe deformities of the craniofacial complex. It is the most commonly encountered odontogenic tumor in Nigeria. Surgical intervention is currently the method of treatment; however identification of altered molecular pathways may inform chemotherapeutic potential. The Protein Patched homolog 1 (PTCH-1) is overexpressed in ameloblastoma. Also, mutation in the MDM2 gene can reduce the tumor suppressor function of p53 and promote ameloblastoma growth. No study however has characterized the molecular profile of African cases of ameloblastoma with a view to developing chemotherapeutic alternatives. The objective was to characterize the PTCH-1 genetic profile of Ameloblastoma in Nigerian patients as a first step in investigating its potential for chemotherapeutic intervention. Methods Twenty-eight FFPE blocks of ameloblastoma cases from Nigerian patients were prepared for antibody processing to PTCH-1 (Polyclonal Anti-PTCH antibody ab39266) and MDM2 (Monoclonal Anti-MDM2 antibody (2A10) ab16895). Cytoplasmic brown staining was considered as positive for PTCH while nuclear staining was positive for MDM2. Results Moderate and strong expressions for PTCH in ameloblast and stellate reticulum were 78.6% and 60.7% respectively. Only 3 (10.7%) cases expressed MDM2. Conclusion The importance of our study is that it supports, in theory, anti-PTCH/SHH chemotherapeutics for Nigerian ameloblastoma cases and also infers the possible additional use of anti-p53 agents. PMID:27386018

  13. Air pollution from gas flaring: new emission factor estimates and detection in a West African aerosol remote-sensing climatology

    NASA Astrophysics Data System (ADS)

    MacKenzie, Rob; Fawole, Olusegun Gabriel; Levine, James; Cai, Xiaoming

    2016-04-01

    Gas flaring, the disposal of gas through stacks in an open-air flame, is a common feature in the processing of crude oil, especially in oil-rich regions of the world. Gas flaring is a prominent source of volatile organic compounds (VOCs), polycyclic aromatic hydrocarbons (PAH), CO, CO2, nitrogen oxides (NOx), SO2 (in "sour" gas only), and soot (black carbon), as well as the release of locally significant amounts of heat. The rates of emission of these pollutants from gas flaring depend on a number of factors including, but not limited to, fuel composition and quantity, stack geometry, flame/combustion characteristics, and prevailing meteorological conditions. Here, we derive new estimated emission factors (EFs) for carbon-containing pollutants (excluding PAH). The air pollution dispersion model, ADMS5, is used to simulate the dispersion of the pollutants from flaring stacks in the Niger delta. A seasonal variation of the dispersion pattern of the pollutant within a year is studied in relation to the movements of the West Africa Monsoon (WAM) and other prevailing meteorological factors. Further, we have clustered AERONET aerosol signals using trajectory analysis to identify dominant aerosol sources at the Ilorin site in West Africa (4.34 oE, 8.32 oN). A 10-year trajectory-based analysis was undertaken (2005-2015, excluding 2010). Of particular interest are air masses that have passed through the gas flaring region in the Niger Delta area en-route the AERONET site. 7-day back trajectories were calculated using the UK Universities Global Atmospheric Modelling Programme (UGAMP) trajectory model which is driven by analyses from the European Centre for Medium-Range Weather Forecasts (ECMWF). From the back-trajectory calculations, dominant sources are identified, using literature classifications: desert dust (DD); Biomass burning (BB); and Urban-Industrial (UI). We use a combination of synoptic trajectories and aerosol optical properties to distinguish a fourth source

  14. The stable hydrogen isotopic composition of sedimentary plant waxes as quantitative proxy for rainfall in the West African Sahel

    NASA Astrophysics Data System (ADS)

    Niedermeyer, Eva M.; Forrest, Matthew; Beckmann, Britta; Sessions, Alex L.; Mulch, Andreas; Schefuß, Enno

    2016-07-01

    Various studies have demonstrated that the stable hydrogen isotopic composition (δD) of terrestrial leaf waxes tracks that of precipitation (δDprecip) both spatially across climate gradients and over a range of different timescales. Yet, reconstructed estimates of δDprecip and corresponding rainfall typically remain largely qualitative, due mainly to uncertainties in plant ecosystem net fractionation, relative humidity, and the stability of the amount effect through time. Here we present δD values of the C31n-alkane (δDwax) from a marine sediment core offshore the Northwest (NW) African Sahel covering the past 100 years and overlapping with the instrumental record of rainfall. We use this record to investigate whether accurate, quantitative estimates of past rainfall can be derived from our δDwax time series. We infer the composition of vegetation (C3/C4) within the continental catchment area by analysis of the stable carbon isotopic composition of the same compounds (δ13Cwax), calculated a net ecosystem fractionation factor, and corrected the δDwax time series accordingly to derive δDprecip. Using the present-day relationship between δDprecip and the amount of precipitation in the tropics, we derive quantitative estimates of past precipitation amounts. Our data show that (a) vegetation composition can be inferred from δ13Cwax, (b) the calculated net ecosystem fractionation represents a reasonable estimate, and (c) estimated total amounts of rainfall based on δDwax correspond to instrumental records of rainfall. Our study has important implications for future studies aiming to reconstruct rainfall based on δDwax; the combined data presented here demonstrate that it is feasible to infer absolute rainfall amounts from sedimentary δDwax in tandem with δ13Cwax in specific depositional settings.

  15. Ethno-botanical study of the African star apple (Chrysophyllum albidum G. Don) in the Southern Benin (West Africa)

    PubMed Central

    2012-01-01

    Background In addition to plant species biology and ecology, understanding the folk knowledge systems related to the use of plant species and how this knowledge system influences the conservation of plant species is an important issue in the implementation of sustainable strategies of biodiversity conservation programs. This study aimed at providing information on the use and local knowledge variation on Chrysophyllum albidum G. Don a multipurpose tree species widely used in southern Benin. Methods Data was collected through 210 structured interviews. Informants were randomly selected from ten villages. The fidelity level and use value of different plant parts of C. albidum were estimated. The variation in ethnobotanical knowledge was assessed by comparing the use value between ethnic, gender and age groups. In order to assess the use pattern of the different plant parts in folk medicine, a correspondence analysis was carried out on the frequency citation of plant parts. Results Four categories of use (food, medicine, firewood and timber) were recorded for C. albidum. With respect to the different plant parts, the fleshy pulp of the African star apple fruit showed high consensus degree as food among the informants. Fifteen diseases were reported to be treated by the different parts of C. albidum in the region. Correspondence analysis revealed the specificity of each part in disease treatment. There was no significant difference among ethnic groups regarding the ethno-botanical use value of C. albidum. However, significant difference existed between genders and among age groups regarding the knowledge of the medical properties of this species. Conclusions C. albidum is well integrated in the traditional agroforestry system of the southern Benin. Despite its multipurpose character, this species remains underutilized in the region. Considering the current threat of habitat degradation, action is needed in order to ensure the long term survival of the species and local

  16. Internalized racism, body fat distribution, and abnormal fasting glucose among African-Caribbean women in Dominica, West Indies.

    PubMed

    Butler, Cleve; Tull, Eugene S; Chambers, Earle C; Taylor, Jerome

    2002-03-01

    The current study examined the relationship of internalized racism to glucose intolerance in a population of Afro-Caribbean women aged 18 to 55. Also of interest was whether this relationship would be differentially influenced by the type of body fat distribution or confounded by the level of hostility. A total of 244 women were selected from a systematic sample of households on the island of Dominica, West Indies. Demographic data together with information on internalized racism were collected by questionnaire. Anthropometric information and fasting blood glucose were also measured. Women with high levels of internalized racism exhibited an increased risk of elevated fasting glucose compared to those with low levels of internalized racism (odds ratio (OR) = 2.4; 95% confidence interval (CI) = 1.1-5.5). There was no difference in mean body mass index (BMI) by level of internalized racism. However those with high internalized racism had a significantly larger waist circumference after adjusting for age, education, hostility, and elevated fasting glucose status. In multivariate analyses controlling for age, education, hostility, and either weight or BMI, internalized racism remained independently associated with elevated fasting glucose. However, once waist circumference was included in the model, the relationship of internalized racism to elevated fasting glucose was not statistically significant. This study demonstrates a significant relationship between internalized racism and abnormal levels of fasting glucose which may be mediated through abdominal fat. The exact nature of the relationship of internalized racism to glucose intolerance may be an important area of future study.

  17. Should I stay or should I go? Dispersal and population structure in small, isolated desert populations of West African crocodiles.

    PubMed

    Velo-Antón, Guillermo; Godinho, Raquel; Campos, João Carlos; Brito, José Carlos

    2014-01-01

    The maintenance of both spatial and genetic connectivity is paramount to the long-term persistence of small, isolated populations living in environments with extreme climates. We aim to identify the distribution of genetic diversity and assess population sub-structuring and dispersal across dwarfed desert populations of Crocodylus suchus, which occur in isolated groups, usually less than five individuals, along the mountains of Mauritania (West Africa). We used both invasive and non-invasive sampling methods and a combination of mitochondrial DNA (12 S and ND4) and microsatellite markers (32 loci and a subset of 12 loci). Our results showed high genetic differentiation and geographic structure in Mauritanian populations of C. suchus. We identified a metapopulation system acting within four river sub-basins (high gene flow and absence of genetic structure) and considerable genetic differentiation between sub-basins (FST range: 0.12-0.24) with rare dispersal events. Effective population sizes tend to be low within sub-basins while genetic diversity is maintained. Our study suggests that hydrographic networks (temporal connections along seasonal rivers during rainy periods) allow C. suchus to disperse and maintain metapopulation dynamics within sub-basins, which attenuate the loss of genetic diversity and the risk of extinction. We highlight the need of hydrographic conservation to protect vulnerable crocodiles isolated in small water bodies. We propose C. suchus as an umbrella species in Mauritania based on ecological affinities shared with other water-dependent species in desert environments. PMID:24740183

  18. Should I stay or should I go? Dispersal and population structure in small, isolated desert populations of West African crocodiles.

    PubMed

    Velo-Antón, Guillermo; Godinho, Raquel; Campos, João Carlos; Brito, José Carlos

    2014-01-01

    The maintenance of both spatial and genetic connectivity is paramount to the long-term persistence of small, isolated populations living in environments with extreme climates. We aim to identify the distribution of genetic diversity and assess population sub-structuring and dispersal across dwarfed desert populations of Crocodylus suchus, which occur in isolated groups, usually less than five individuals, along the mountains of Mauritania (West Africa). We used both invasive and non-invasive sampling methods and a combination of mitochondrial DNA (12 S and ND4) and microsatellite markers (32 loci and a subset of 12 loci). Our results showed high genetic differentiation and geographic structure in Mauritanian populations of C. suchus. We identified a metapopulation system acting within four river sub-basins (high gene flow and absence of genetic structure) and considerable genetic differentiation between sub-basins (FST range: 0.12-0.24) with rare dispersal events. Effective population sizes tend to be low within sub-basins while genetic diversity is maintained. Our study suggests that hydrographic networks (temporal connections along seasonal rivers during rainy periods) allow C. suchus to disperse and maintain metapopulation dynamics within sub-basins, which attenuate the loss of genetic diversity and the risk of extinction. We highlight the need of hydrographic conservation to protect vulnerable crocodiles isolated in small water bodies. We propose C. suchus as an umbrella species in Mauritania based on ecological affinities shared with other water-dependent species in desert environments.

  19. The West African Mauritanid metamorphic suite of Proterozoic age in the subsurface of peninsular Florida and environs

    SciTech Connect

    Winston, G.O.

    1993-03-01

    A high and low-grade Gondwanan metamorphic terrane is revealed by 14 wells in Florida and environs. Two high-grade metamorphics (gneiss and schist) are located in central Florida and are probably Early Proterozoic in age. The 12 other wells contain low-grade metamorphic suites, principally composed of inter-bedded argillites, acid volcanics and quartzites belonging to the Mauritanid sequence of West Africa. These suites are present in south Georgia, north Florida and offshore; a 3,975-foot section was penetrated in one well. These widespread metamorphic rocks are probably the terrane into which the Cambrian Osceola granite of central Florida was intruded. The two grades of metamorphics represent Early and Late Proterozoic episodes of sedimentation, each followed by metamorphism and erosion. Lower Ordovician to Devonian sediments were deposited on this terrane in southern Georgia and northern Florida. In the Early Jurassic, volcanics completely covered southern Florida, concealing the nature of the old underlying surface. Younger Mesozoic sediments eventually buried the entire Pre-Cambrian-Lower Jurassic terrane.

  20. Holocene dust records from the West African Sahel and their implications for changes in climate and land surface conditions

    NASA Astrophysics Data System (ADS)

    Cockerton, Helen E.; Holmes, Jonathan A.; Street-Perrott, F. Alayne; Ficken, Katherine J.

    2014-07-01

    We reconstructed aeolian dust accumulation during the Holocene from two radiocarbon-dated lake-sediment sequences from the Manga Grasslands in northeastern Nigeria in order to investigate long-term changes in the Harmattan dust system over West Africa and evaluate their possible causes. Flux values were low in the early Holocene, decreasing further to a minimum at around 6.2 kyr B.P. after which time they increased, steadily until around 2 kyr B.P. and then more sharply after this time. The long-term variations in dust flux agree broadly with changes in the exposed area of the Lake Chad Basin to the northeast of the study sites, which vary inversely with the volume of Paleolake Megachad. More proximal sources of dust, including the fine fraction of local dune sand and floodplains of nearby rivers, have also made a contribution to the total dust load during times of enhanced dune and fluvial activity. Sharp rises in dust flux over the past century may be related to human activity. Broad patterns of change in dust flux during the Holocene agree with other reconstructions over the same period. However, we see no evidence for a stepped rise during the middle Holocene, as seen at some sites from the northeastern tropical Atlantic, suggesting that controls on the Harmattan dust system have differed from those affecting dust deposition elsewhere across northern Africa.

  1. Development of Onchocerca volvulus (Filarioidea: Onchocercidae) in the West African black fly Simulium yahense (Diptera: Simuliidae) in Liberia.

    PubMed

    Trpis, M; Wergin, W P; Murphy, C A

    2001-12-01

    Simulium yahense black flies infected with microfilaria of Onchocerca volvulus were kept in a defined insectary environment in Liberia, West Africa. A daily sample of infected flies was dissected for larvae developing in the thoracic muscles and examined for growth in stadial development. Microfilariae ingested by black flies transformed to the L1 larval stage without molting. Successive larval development included molting to the L2 stage and, finally, to the L3 stage, which was infective in humans. The cephalic cap, consisting of a laterally located hook and central stoma, occurs in the first larval stage. The caudal appendix and the laterally located anal opening are apparent in the L1 larva. In the L2 stage, the cephalic cap is lost and the large circular stoma becomes surrounded with elevated flaps. The caudal appendix was lost after larvae molted to the L3 stage, and in its place, 3 terminal papillae developed. Sense organs, such as 2 opposing phasmids and 8 papillae that were arranged into 2 circles, developed in the cephalic region of the L3 larva. The evidence of pathological consequences due to the presence of the L3 larva in the fly host are illustrated and discussed. PMID:11780809

  2. Radiative forcing of Sahara dust and its impacts on the hydrological cycle in the West African monsoon system

    NASA Astrophysics Data System (ADS)

    Zhao, C.; Liu, X.; Leung, L.; Hagos, S. M.

    2010-12-01

    The WRF-Chem model is applied to simulate the radiative forcing of dust and its impacts on the hydrological cycle during the monsoon season over West Africa (WA). The GOCART dust emission scheme is coupled into two aerosol models (MADE/SORGAM and MOSAIC) in WRF-Chem. During the monsoon season, dust is a dominant contributor to AOD near the dust source regions. Dust heats the atmosphere, and warms the surface in the nighttime through trapping the longwave radiation but cools the surface in the daytime through reducing the shortwave radiation. Dust modifies the surface energy budget through changing radiation, latent heat, and sensible heat fluxes, and results in large surface cooling effect in the afternoon but warming effect in the early morning during the monsoon season over WA. In the standard model configuration, the dust effect on total daily precipitation is small in both strong and weak monsoon years, but is sensitive to the dust absorbing properties. On the other hand, the dust-driven change of the stability of atmosphere significantly reduces the diurnal variation of precipitation during the monsoon season over WA, and improves the model simulation when compared to available observations.

  3. Visible and infrared properties of unaltered to weathered rocks from Precambrian granite-greenstone terrains of the West African Craton

    NASA Astrophysics Data System (ADS)

    Metelka, Václav; Baratoux, Lenka; Jessell, Mark W.; Naba, Séta

    2015-12-01

    In situ and laboratory 0.35 μm-2.5 μm spectra of rocks from a Paleoproterozoic granite-greenstone terrain along with its Neoproterozoic sedimentary cover and derived regolith materials were examined in western Burkina Faso. The reflectance spectra show the influence of typical arid to semi-arid weathering with the formation of desert varnish, iron films, and dust coatings. Fe and Mg-OH absorption features related to chlorite, amphibole, pyroxene, epidote, and biotite are observable in the mafic and intermediate meta-volcanic rocks as well as in the granodiorites and tonalites. Al-OH absorption caused by kaolinite, smectite, illite/muscovite are typical for meta-volcano-sedimentary schists, Tarkwaian-type detrital meta-sediments, sandstones of the Taoudeni basin, all of the weathered surfaces and regolith materials. Ferric and ferrous iron absorptions related to both primary rock-forming minerals and secondary weathering minerals (goethite, hematite) were observed in most of the sampled materials. The results show that although weathering alters the spectral signature of the fresh rock, indicative absorption features located in the short wave infrared region remain detectable. In addition, spectra of soils partially reflect the mineral composition of the weathered rock surfaces. The analysis of the hyperspectral data shows the potential of differentiating between the sampled surfaces. The library presents a primary database for the geological and regolith analysis of remote sensing data in West Africa.

  4. Large-scale impacts of climate change on tropical West African ecosystems over the past ~540,000 years

    NASA Astrophysics Data System (ADS)

    Gosling, William; Miller, Charlotte; Kemp, David; Coe, Angela; Gilmour, Iain

    2016-04-01

    A paucity of empirical non-marine data means that uncertainty surrounds the impact of climate change on terrestrial ecosystems in tropical regions. The sedimentary-fill of the Bosumtwi impact crater (Ghana) provides the longest Quaternary terrestrial archive of environmental change in Africa, spanning the last ~540,000 years. Here we present a reconstruction of vegetation biomes and moisture availability in tropical West Africa for the past ~540,000 years using pollen analysis and the nitrogen isotope composition of bulk organic matter preserved in sediments from Lake Bosumtwi. Variations in grass pollen abundance (0-99%) indicate abrupt transitions between savannah and woodland biomes. Coeval variations in the nitrogen isotopic composition of organic matter indicate that intervals of savannah expansion coincided with minimum lake-levels and low regional moisture availability. The observed changes responded to orbitally paced global climate variations on both glacial-interglacial and shorter timescales. Importantly, the magnitude and abruptness of ecosystem change revealed by our data exceeds that previously determined from marine records, demonstrating for the first time the true sensitivity of tropical regions to Quaternary climate change.

  5. A one-year study of the diurnal cycle of meteorology, clouds and radiation in the West African Sahel region

    DOE PAGES

    Collow, Allison B.; Ghate, Virendra P.; Miller, Mark A.; Trabachino, Lynne C.

    2015-09-09

    Here, the diurnal cycles of meteorological and radiation variables are analysed during the wet and dry seasons over the Sahel region of West Africa during 2006 using surface data collected by the Atmospheric Radiation Measurement (ARM) programme's Mobile Facility, satellite radiation measurements from the Geostationary Earth Radiation Budget (GERB) instrument aboard Meteosat 8, and reanalysis products from the National Centers for Environmental Prediction (NCEP). The meteorological analysis builds upon past studies of the diurnal cycle in the region by incorporating diurnal cycles of lower tropospheric wind profiles, thermodynamic profiles, integrated water vapour and liquid water measurements, and cloud radar measurementsmore » of frequency and location. These meteorological measurements are complemented by 3 h measurements of the diurnal cycles of the top-of-atmosphere (TOA) and surface short-wave (SW) and long-wave (LW) radiative fluxes and cloud radiative effects (CREs), and the atmospheric radiative flux divergence (RFD) and atmospheric CREs. Cirrus cloudiness during the dry season is shown to peak in coverage in the afternoon, while convective clouds during the wet season are shown to peak near dawn and have an afternoon minimum related to the rise of the lifting condensation level into the Saharan Air Layer. The LW and SW RFDs and CREs exhibit diurnal cycles during both seasons, but there is a relatively small difference in the LW cycles during the two seasons (10 – 30 W m–2 depending on the variable and time of day). Small differences in the TOA CREs during the two seasons are overwhelmed by large differences in the surface SW CREs, which exceed 100 W m–2. A significant surface SW CRE during the wet season combined with a negligible TOA SW CRE produces a diurnal cycle in the atmospheric CRE that is modulated primarily by the SW surface CRE, peaks at midday at ~150 W m–2, and varies widely from day to day.« less

  6. A one-year study of the diurnal cycle of meteorology, clouds and radiation in the West African Sahel region

    SciTech Connect

    Collow, Allison B.; Ghate, Virendra P.; Miller, Mark A.; Trabachino, Lynne C.

    2015-09-09

    Here, the diurnal cycles of meteorological and radiation variables are analysed during the wet and dry seasons over the Sahel region of West Africa during 2006 using surface data collected by the Atmospheric Radiation Measurement (ARM) programme's Mobile Facility, satellite radiation measurements from the Geostationary Earth Radiation Budget (GERB) instrument aboard Meteosat 8, and reanalysis products from the National Centers for Environmental Prediction (NCEP). The meteorological analysis builds upon past studies of the diurnal cycle in the region by incorporating diurnal cycles of lower tropospheric wind profiles, thermodynamic profiles, integrated water vapour and liquid water measurements, and cloud radar measurements of frequency and location. These meteorological measurements are complemented by 3 h measurements of the diurnal cycles of the top-of-atmosphere (TOA) and surface short-wave (SW) and long-wave (LW) radiative fluxes and cloud radiative effects (CREs), and the atmospheric radiative flux divergence (RFD) and atmospheric CREs. Cirrus cloudiness during the dry season is shown to peak in coverage in the afternoon, while convective clouds during the wet season are shown to peak near dawn and have an afternoon minimum related to the rise of the lifting condensation level into the Saharan Air Layer. The LW and SW RFDs and CREs exhibit diurnal cycles during both seasons, but there is a relatively small difference in the LW cycles during the two seasons (10 – 30 W m–2 depending on the variable and time of day). Small differences in the TOA CREs during the two seasons are overwhelmed by large differences in the surface SW CREs, which exceed 100 W m–2. A significant surface SW CRE during the wet season combined with a negligible TOA SW CRE produces a diurnal cycle in the atmospheric CRE that is modulated primarily by the SW surface CRE, peaks at midday at ~150 W m–2, and varies widely from day to day.

  7. Standardizing visual control devices for tsetse flies: West African species Glossina tachinoides, G. palpalis gambiensis and G. morsitans submorsitans.

    PubMed

    Rayaisse, Jean-Baptiste; Kröber, Thomas; McMullin, Andrew; Solano, Philippe; Mihok, Steve; Guerin, Patrick M

    2012-01-01

    Here we describe field trials designed to standardize tools for the control of Glossina tachinoides, G. palpalis gambiensis and G.morsitans submorsitans in West Africa based on existing trap/target/bait technology. Blue and black biconical and monoconical traps and 1 m(2) targets were made in either phthalogen blue cotton, phthalogen blue cotton/polyester or turquoise blue polyester/viscose (all with a peak reflectance between 450-480 nm) and a black polyester. Because targets were covered in adhesive film, they proved to be significantly better trapping devices than either of the two trap types for all three species (up to 14 times more for G. tachinoides, 10 times more for G. palpalis gambiensis, and 6.5 times for G. morsitans submorsitans). The relative performance of the devices in the three blue cloths tested was the same when unbaited or baited with a mixture of phenols, 1-octen-3-ol and acetone. Since insecticide-impregnated devices act via contact with flies, we enumerated which device (traps or targets) served as the best object for flies to land on by also covering the cloth parts of traps with adhesive film. Despite the fact that the biconical trap proved to be the best landing device for the three species, the difference over the target (20-30%) was not significant. This experiment also allowed an estimation of trap efficiency, i.e. the proportion of flies landing on a trap that are caught in its cage. A low overall efficiency of the biconical or monoconical traps of between 11-24% was recorded for all three species. These results show that targets can be used as practical devices for population suppression of the three species studied. Biconical traps can be used for population monitoring, but a correction factor of 5-10 fold needs to be applied to captures to compensate for the poor trapping efficiency of this device for the three species.

  8. At-risk serum cholesterol profile at both ends of the nutrition spectrum in West African adults? The Benin study.

    PubMed

    Delisle, Hélène; Ntandou, Gervais; Sodjinou, Roger; Couillard, Charles; Després, Jean-Pierre

    2013-04-19

    Low HDL-cholesterol (HDL-C), using as cut-offs 1.03 mmol/L in men and 1.29 mmol/L in women, was observed in more than 25% apparently healthy adults (n = 541) in a cross-sectional study on nutrition transition and cardiometabolic risk factors (CMRF) in Benin, West Africa. Both overweight/obesity (35.3%) and underweight (11.3%) were present, displaying the double burden of malnutrition. We examined in more depth the association of low HDL-C with nutrition and with other CMRF. Metabolic syndrome components were assessed, plus the ratio of total cholesterol (TC)/HDL-C and serum homocysteine. Insulin resistance was based on Homeostasis Model Assessment. We also measured BMI and body composition by bio-impedance. Dietary quality was appraised with two non-consecutive 24 h recalls. Low HDL-C was associated with much higher TC/HDL-C and more abdominal obesity in men and women and with more insulin resistance in women. The rate of low HDL-C was highest (41.9%) among the overweight/obese subjects (BMI ≥ 25), but it also reached 31.1% among the underweight (BMI < 18.5), compared with 17.3% among normal-weight subjects (p < 0.001). Lower dietary micronutrient adequacy, in particular, in vitamins A, B3, B12, zinc and calcium, was associated with low HDL-C when controlling for several confounders. This suggests that at-risk lipoprotein cholesterol may be associated with either underweight or overweight/obesity and with poor micronutrient intake.

  9. Future Water Resources Assessment for West African River Basins Under Climate Change, Population Growth and Irrigation Development

    NASA Astrophysics Data System (ADS)

    Wisser, D.; Ibrahim, B.; Proussevitch, A. A.

    2014-12-01

    West Africa economies rely on rain-fed agriculture and are extremely vulnerable to changes in precipitation. Results from the most recent generation of regional climate models suggest increases in rainy season rainfall variability (delayed rainy season onset, increased probability of dry spells, shorter rainy season duration) despite a moderate increase in rainy season total precipitation. These changes could potentially have detrimental effects on crop yield and food security. Additional pressures on water resources come from increased demand as a result of high population growth rates (~3% per year). Increased water storage and irrigation can help improve crop yields but future assessments of water resources are needed to prioritize irrigation development as an adaptation option. Increased water abstraction, in turn can impact water availability in downstream regions so that an integrated assessment of future water availability and demand is needed. We use a set of 15 RCM outputs from the CORDEX data archive to drive WBMplus, a hydrological model and simulate water availability under climate change. Based on estimated water constraints, we develop scenarios to expand irrigated areas (from the current 1% of all croplands) and calculate the effects on water scarcity, taking into account increased demand for domestic consumption and livestock water demand, at a spatial resolution of 10 km. Results around the 2050's indicate large potential to develop irrigated areas on ground and surface water and increase local water storage without increasing water scarcity downstream for many river basins in the region that could help alleviate pressures on the cropping systems and thereby increase food security.

  10. Standardizing Visual Control Devices for Tsetse Flies: West African Species Glossina tachinoides, G. palpalis gambiensis and G. morsitans submorsitans

    PubMed Central

    Rayaisse, Jean-Baptiste; Kröber, Thomas; McMullin, Andrew; Solano, Philippe; Mihok, Steve; Guerin, Patrick M.

    2012-01-01

    Here we describe field trials designed to standardize tools for the control of Glossina tachinoides, G. palpalis gambiensis and G.morsitans submorsitans in West Africa based on existing trap/target/bait technology. Blue and black biconical and monoconical traps and 1 m2 targets were made in either phthalogen blue cotton, phthalogen blue cotton/polyester or turquoise blue polyester/viscose (all with a peak reflectance between 450–480 nm) and a black polyester. Because targets were covered in adhesive film, they proved to be significantly better trapping devices than either of the two trap types for all three species (up to 14 times more for G. tachinoides, 10 times more for G. palpalis gambiensis, and 6.5 times for G. morsitans submorsitans). The relative performance of the devices in the three blue cloths tested was the same when unbaited or baited with a mixture of phenols, 1-octen-3-ol and acetone. Since insecticide-impregnated devices act via contact with flies, we enumerated which device (traps or targets) served as the best object for flies to land on by also covering the cloth parts of traps with adhesive film. Despite the fact that the biconical trap proved to be the best landing device for the three species, the difference over the target (20–30%) was not significant. This experiment also allowed an estimation of trap efficiency, i.e. the proportion of flies landing on a trap that are caught in its cage. A low overall efficiency of the biconical or monoconical traps of between 11–24% was recorded for all three species. These results show that targets can be used as practical devices for population suppression of the three species studied. Biconical traps can be used for population monitoring, but a correction factor of 5–10 fold needs to be applied to captures to compensate for the poor trapping efficiency of this device for the three species. PMID:22348159

  11. Recruitment patterns of young-of-the-year mugilid fishes in a West African estuary impacted by climate change

    NASA Astrophysics Data System (ADS)

    Trape, Sébastien; Durand, Jean-Dominique; Guilhaumon, François; Vigliola, Laurent; Panfili, Jacques

    2009-11-01

    With the persistence of the sub-Saharan drought since the 1970s, the Sine Saloum estuary (Senegal) - the second largest coastal Biosphere Reserve of West-Africa - has become an "inverse estuary" and hypersaline (salinity > 60) in its upstream part. A one-year survey was conducted from April 2007 to March 2008 at eight sites distributed along the salinity gradient, to investigate the recruitment patterns of young-of-the-year mugilids in such an impacted ecosystem. Fishes were sampled monthly with a conical net and a beach seine in salinities ranging from 31 to 104. Samples were identified to the species level. For the smallest individuals (<20 mm SL) a PCR-RFLP technique, developed on the mitochondrial 16S ribosomal RNA region, was used for identification. A total of 8438 juveniles belonging to six of the eight species of mugilids known for the tropical Eastern Atlantic were collected: Mugil bananensis, Mugil cephalus, Mugil curema, Liza dumerili, Liza falcipinnis and Liza grandisquamis. One species, L. dumerili, represented 89% of the total catch. Length-frequency distributions revealed that M. cephalus and L. dumerili preferentially recruited during the dry season whereas the recruitment of M. curema, M. bananensis and L. falcipinnis generally occurred during the wet season. Minimal size at recruitment ranged from 9 to 19 mm SL depending on the species, the smallest size being that of L. dumerili. Despite the general salinity increase in the estuary, most parts of the Sine Saloum were suitable for the juveniles. Only the hypersaline area in the uppermost part of the estuary presented very low fish abundance for all species. According to the species, small recruits (12-20 mm SL) were collected at salinities up to 47-78, suggesting that osmoregulatory capacities had been gained early during ontogenesis, possibly resulting from an adaptation of these populations to changing environmental conditions.

  12. Source potential of the Zairian onshore pre-salt subbasins of the West African Aptian salt basin

    SciTech Connect

    Swirydczuk, K.; Tshiband, D.; Nyimi, M.; Musombo, I.; Mbalambala, K.

    1996-08-01

    Three pre-salt subbasins are located onshore in Zaire in the Congo-Cabinda Basin. Production exists to the west, and extensive outcrops of Mavuma tar sands are located immediately to the east of these subbasins. Five pre-salt wells confirmed that thick Barremian lacustrine claystones of the Bucomazi Formation form the main source horizon in all the subbasins. Upper Bucomazi claystones average 4% and reach 12% TOC. Lower Bucomazi claystones average 2% (high of 6%). A mixed Type I/Type II algal oil-prone kerogen predominates. Up to 1% TOC is present in claystones in the underlying Lucula section. Dry pyrolysis shows significant differences in kerogen kinetics from subbasin to subbasin. R{sub o} and T{sub max} were used to model heat flow through time. Ages were from biostratigraphic analyses and radiometric dating of thin volcanics within the Lucula and Bucomazi formations. Apatite fission track analyses provided control on uplift history. Pseudowells were used in maturation modelling to predict source rock maturity in the subbasins. The upper Bucomazi is immature except in the deeper parts of two of the subbasins. The Lower - Bucomazi and Upper Lucula are mature in all subbasins and in the deepest subbasins are overmature. Oil generation occurred shortly after deposition of the Loeme Salt. Analyses of Lindu oil support this early migration. Estimates of oil that may have been generated in the eastern-most subbasin suggest that extensive Mavuma tar sands, which have been typed to lacustrine source, could have been sourced from this subbasin.

  13. Standardizing visual control devices for tsetse flies: West African species Glossina tachinoides, G. palpalis gambiensis and G. morsitans submorsitans.

    PubMed

    Rayaisse, Jean-Baptiste; Kröber, Thomas; McMullin, Andrew; Solano, Philippe; Mihok, Steve; Guerin, Patrick M

    2012-01-01

    Here we describe field trials designed to standardize tools for the control of Glossina tachinoides, G. palpalis gambiensis and G.morsitans submorsitans in West Africa based on existing trap/target/bait technology. Blue and black biconical and monoconical traps and 1 m(2) targets were made in either phthalogen blue cotton, phthalogen blue cotton/polyester or turquoise blue polyester/viscose (all with a peak reflectance between 450-480 nm) and a black polyester. Because targets were covered in adhesive film, they proved to be significantly better trapping devices than either of the two trap types for all three species (up to 14 times more for G. tachinoides, 10 times more for G. palpalis gambiensis, and 6.5 times for G. morsitans submorsitans). The relative performance of the devices in the three blue cloths tested was the same when unbaited or baited with a mixture of phenols, 1-octen-3-ol and acetone. Since insecticide-impregnated devices act via contact with flies, we enumerated which device (traps or targets) served as the best object for flies to land on by also covering the cloth parts of traps with adhesive film. Despite the fact that the biconical trap proved to be the best landing device for the three species, the difference over the target (20-30%) was not significant. This experiment also allowed an estimation of trap efficiency, i.e. the proportion of flies landing on a trap that are caught in its cage. A low overall efficiency of the biconical or monoconical traps of between 11-24% was recorded for all three species. These results show that targets can be used as practical devices for population suppression of the three species studied. Biconical traps can be used for population monitoring, but a correction factor of 5-10 fold needs to be applied to captures to compensate for the poor trapping efficiency of this device for the three species. PMID:22348159

  14. Occurrence, distribution and health risk from polycyclic aromatic compounds (PAHs, oxygenated-PAHs and azaarenes) in street dust from a major West African Metropolis.

    PubMed

    Bandowe, Benjamin A Musa; Nkansah, Marian Asantewah

    2016-05-15

    Scientific evidence suggests that the burden of disease on urban residents of sub-Saharan African Countries is increasing, partly as a result of exposure to elevated concentrations of toxic environmental chemicals. However, characterization of the levels, composition pattern and sources of polycyclic aromatic compounds (PACs) in environmental samples from African cities is still lacking. This study measured the PAHs, oxygenated-PAHs (OPAHs) and azaarene (AZAs) content of street dusts collected from Kumasi, Ghana (a major metropolis located in the tropical forest zone of West Africa). The ∑Alkyl+parent-PAHs, ∑OPAHs and ∑AZAs concentration in street dust averaged 2570 ng g(-1) (range: 181-7600 ng g(-1)), 833 ng g(-1) (57-4200 ng g(-1)) and 73 ng g(-1) (3.3-240 ng g(-1)), respectively. The concentrations of ∑Alkyl+parent-PAHs were strongly correlated (n=25) with ∑OPAHs (r=0.96, p<0.01) and ∑AZAs (r=0.94, p<0.01). The ∑OPAHs concentrations were also strongly correlated with ∑AZAs (r=0.91, p<0.01). Concentrations of individual PAHs in these street dusts were enriched at between 12 and 836 compared to their average concentrations in background soils from same city, demonstrating the high influence of traffic emissions. Several individual OPAHs and AZAs had higher concentrations than their related and often monitored parent-PAHs. The estimated incremental lifetime cancer risks due to the parent-PAHs in street dusts was >10(-6) indicating high risk of contracting cancer from exposure to street dust from Kumasi. The contribution of OPAHs, AZAs, and alkyl-PAHs in street dust to cancer risk could not be quantified because of lack of toxicity equivalency factors for these compounds; however this could be significant because of their high concentration and known higher toxicity of some polar PACs and alkyl-PAHs than their related parent-PAHs.

  15. Anaemia and zidovudine-containing antiretroviral therapy in paediatric antiretroviral programmes in the IeDEA Paediatric West African Database to evaluate AIDS

    PubMed Central

    Renner, Lorna A; Dicko, Fatoumata; Kouéta, Fla; Malateste, Karen; Gueye, Ramatoulaye D; Aka, Edmond; Eboua, Tanoh K; Azondékon, Alain; Okomo, Uduok; Touré, Pety; Ekouévi, Didier; Leroy, Valeriane

    2013-01-01

    Introduction There is a risk of anaemia among HIV-infected children on antiretroviral therapy (ART) containing zidovudine (ZDV) recommended in first-line regimens in the WHO guidelines. We estimated the risk of severe anaemia after initiation of a ZDV-containing regimen in HIV-infected children included in the IeDEA West African database. Methods Standardized collection of data from HIV-infected children (positive PCR<18 months or positive serology ≥18 months) followed up in HIV programmes was included in the regional IeDEA West Africa collaboration. Ten clinical centres from seven countries contributed (Benin, Burkina Faso, Côte d'Ivoire, Gambia, Ghana, Mali and Senegal) to this collection. Inclusion criteria were age <16 years and starting ART. We explored the data quality of haemoglobin documentation over time and the incidence and predictors of severe anaemia (Hb<7g/dL) per 100 child-years of follow-up over the duration of first-line antiretroviral therapy. Results As of December 2009, among the 2933 children included in the collaboration, 45% were girls, median age was five years; median CD4 cell percentage was 13%; median weight-for-age z-score was −2.7; and 1772 (60.4%) had a first-line ZDV-containing regimen. At baseline, 70% of the children with a first-line ZDV-containing regimen had a haemoglobin measure available versus 76% in those not on ZDV (p≤0.01): the prevalence of severe anaemia was 3.0% (n=38) in the ZDV group versus 10.2% (n=89) in those without (p<0. 01). Over the first-line follow-up, 58.9% of the children had ≥1 measure of haemoglobin available in those exposed to ZDV versus 60.4% of those not (p=0.45). Severe anaemia occurred in 92 children with an incidence of 2.47 per 100 child-years of follow-up in those on a ZDV-containing regimen versus 4.25 in those not (p≤0.01). Adjusted for age at ART initiation and first-line regimen, a weight-for-age z-score ≤−3 was a strong predictor associated with a 5.59 times risk of severe

  16. Overcoming Phosphorus Deficiency in West African Pearl Millet and Sorghum Production Systems: Promising Options for Crop Improvement

    PubMed Central

    Gemenet, Dorcus C.; Leiser, Willmar L.; Beggi, Francesca; Herrmann, Ludger H.; Vadez, Vincent; Rattunde, Henry F. W.; Weltzien, Eva; Hash, Charles T.; Buerkert, Andreas; Haussmann, Bettina I. G.

    2016-01-01

    West Africa (WA) is among the most food insecure regions. Rapid human population growth and stagnating crop yields greatly contribute to this fact. Poor soil fertility, especially low plant available phosphorus (P) is constraining food production in the region. P-fertilizer use in WA is among the lowest in the world due to inaccessibility and high prices, often unaffordable to resource-poor subsistence farmers. This article provides an overview of soil P-deficiency in WA and opportunities to overcome it by exploiting sorghum and pearl millet genetic diversity. The topic is examined from the perspectives of plant breeding, soil science, plant physiology, plant nutrition, and agronomy, thereby referring to recent results obtained in a joint interdisciplinary research project, and reported literature. Specific objectives are to summarize: (1) The global problem of P scarcity and how it will affect WA farmers; (2) Soil P dynamics in WA soils; (3) Plant responses to P deficiency; (4) Opportunities to breed for improved crop adaptation to P-limited conditions; (5) Challenges and trade-offs for improving sorghum and pearl millet adaptation to low-P conditions in WA; and (6) Systems approaches to address soil P-deficiency in WA. Sorghum and pearl millet in WA exhibit highly significant genetic variation for P-uptake efficiency, P-utilization efficiency, and grain yield under P-limited conditions indicating the possibility of breeding P-efficient varieties. Direct selection under P-limited conditions was more efficient than indirect selection under high-P conditions. Combining P-uptake and P-utilization efficiency is recommendable for WA to avoid further soil mining. Genomic regions responsible for P-uptake, P-utilization efficiency, and grain yield under low-P have been identified in WA sorghum and pearl millet, and marker-assisted selection could be possible once these genomic regions are validated. Developing P-efficient genotypes may not, however, be a sustainable

  17. Measurements of NO2, SO2, NH3, HNO3 and O3 in West African urban environments

    NASA Astrophysics Data System (ADS)

    Adon, Marcellin; Yoboué, Véronique; Galy-Lacaux, Corinne; Liousse, Catherine; Diop, Babakar; Doumbia, El Hadji Thierno; Gardrat, Eric; Ndiaye, Seydi Ababacar; Jarnot, Christian

    2016-06-01

    In this paper, we present the measurements of atmospheric gas concentrations of NO2, SO2, NH3, HNO3, and O3 performed at two traffic sites in the context of the POLCA (Pollution of African Capitals) program. These gases were measured using a passive sampling technique from Jan. 2008 to Dec. 2009 at Dakar and from Jun. 2008 to Dec. 2009 at Bamako. In addition, during these periods there were two intensive measurement campaigns (from 19 Jan. to 2 Feb. 2009 at Bamako and from 30 Nov. to 13 Dec. 2009 at Dakar) where real-time active analysers were used to measure NO2 and SO2. Results show that Dakar has a pollution level for NO2 and SO2 higher than that of Bamako, whereas it is lower for NH3 concentrations. Monthly values of NO2 range between 21.1 and 43.5 ppb in Dakar with an annual mean concentration of 31.7 ppb (59.6 μg/m3). NO2 values in Bamako are 9.4-22.6 ppb with a mean of 16.2 ppb. At Dakar, the mean annual NO2 limit value (21.3 ppb or 40 μg/m3) recommended by the World Health Organization (WHO) is widely exceeded. The mean annual concentration of SO2 is 15.9 ppb in Dakar and 3.6 ppb in Bamako. These differences may be explained by different sources of traffic between Bamako (with mainly gasoline vehicles) and Dakar (with mainly diesel vehicles). The annual mean NH3 concentration is about two times higher in Bamako (46.7 ppb) than in Dakar (21.1 ppb). In addition to other possible sources, we assume that the ammonia from domestic fires and uncontrolled garbage incineration may have more influence at Bamako than at Dakar. The mean annual concentrations of HNO3 and O3 are 1.3 ppb and 7.7 ppb in Dakar and 0.6 ppb and 5.1 ppb in Bamako, respectively. Seasonal variation in measured gas concentrations are low in Bamako and more pronounced in Dakar, except for HNO3 and NH3. At Dakar, NO2 and SO2 daily mean concentrations are higher during the weekdays than on weekends, when urban activities are reduced, whereas at Bamako, no significant difference was observed

  18. West African monsoon dynamics and precipitation: the competition between global SST warming and CO2 increase in CMIP5 idealized simulations

    NASA Astrophysics Data System (ADS)

    Gaetani, Marco; Flamant, Cyrille; Bastin, Sophie; Janicot, Serge; Lavaysse, Christophe; Hourdin, Frederic; Braconnot, Pascale; Bony, Sandrine

    2016-04-01

    Climate variability associated with the West African monsoon (WAM) has important environmental and socio-economic impacts in the region. However, state-of-the-art climate models still struggle in producing reliable climate predictions. An important cause of this low predictive skill is the sensitivity of climate models to different forcings. In this study, the mechanisms linking the WAM dynamics to the CO2 forcing are investigated, by comparing the effect of the CO2 direct radiative effect with its indirect effect mediated by the global sea surface warming. The July-to-September WAM variability is studied in climate simulations extracted from the Coupled Model Intercomparison Project Phase 5 archive, driven by prescribed sea surface temperature (SST). The individual roles of global SST warming and CO2 atmospheric concentration increase are investigated through idealized experiments simulating a 4 K warmer SST and a quadrupled CO2 concentration, respectively. Results show opposite and competing responses in the WAM dynamics and precipitation. A dry response (-0.6 mm/day) to the SST warming is simulated in the Sahel, with dryer conditions over western Sahel (-0.8 mm/day). Conversely, the CO2 increase produces wet conditions (+0.5 mm/day) in the Sahel, with the strongest response over central-eastern Sahel (+0.7 mm/day). The associated responses in the atmospheric dynamics are also analysed, showing that the SST warming affects the Sahelian precipitation through modifications in the global tropical atmospheric dynamics, reducing the importance of the regional drivers, while the CO2 increase reinforces the coupling between precipitation and regional dynamics. A general agreement in model responses demonstrates the robustness of the identified mechanisms linking the WAM dynamics to the CO2 direct and indirect forcing, and indicates that these primary mechanisms are captured by climate models. Results also suggest that the spread in future projections may be caused by

  19. Physiological and haematological indices suggest superior heat tolerance of white-coloured West African Dwarf sheep in the hot humid tropics.

    PubMed

    Fadare, Adelodun O; Peters, Sunday O; Yakubu, Abdulmojeed; Sonibare, Adekayode O; Adeleke, Matthew A; Ozoje, Michael O; Imumorin, Ikhide G

    2013-01-01

    Coat colour contributes to physiological adaptation in mammals and mediates response to thermal stress. Twenty-four adult West African Dwarf sheep of both sexes and with different coat colour types were used in this study. We measured rectal temperature (RT), respiratory rate (RR) and pulse rate (PR) before sunrise and sunset during the late dry season (January-March) and early rainy season (April-June) as well as packed cell volume (PCV), red blood cell (RBC) count, white blood cell (WBC) count, plasma sodium (Na(+)) and potassium (K(+)). Animals with black coat colour had the highest (P < 0.05) mean values of 38.92 ± 0.03 °C, 65.09 ± 1.06 breaths/min, 81.35 ± 0.78 beats/min, 1.70 ± 0.01 for RT, RR, PR and heat stress index (HSI), respectively, followed by brown mouflon and brown with extensive white, while the Badger Face coloured sheep had the least mean values. There were significant (P < 0.05) differences between male and female sheep for RT, RR, PR and HSI. Season had a significant (P < 0.05) effect on RT, RR, PR and HSI. Coat colour and sex also significantly (P < 0.01) affected RBC, WBC, Na(+) and K(+). Seasonal variation (P < 0.05) in all the blood parameters was observed, with the exception of PCV. Interaction effect of coat colour and sex was significant (P < 0.05) on RT and HSI. Correlation coefficients among the measured traits ranged from positive to negative values. These results indicate that selection of white-coloured sheep to attenuate heat stress is desirable in the hot humid tropics.

  20. Physiological and haematological indices suggest superior heat tolerance of white-coloured West African Dwarf sheep in the hot humid tropics.

    PubMed

    Fadare, Adelodun O; Peters, Sunday O; Yakubu, Abdulmojeed; Sonibare, Adekayode O; Adeleke, Matthew A; Ozoje, Michael O; Imumorin, Ikhide G

    2013-01-01

    Coat colour contributes to physiological adaptation in mammals and mediates response to thermal stress. Twenty-four adult West African Dwarf sheep of both sexes and with different coat colour types were used in this study. We measured rectal temperature (RT), respiratory rate (RR) and pulse rate (PR) before sunrise and sunset during the late dry season (January-March) and early rainy season (April-June) as well as packed cell volume (PCV), red blood cell (RBC) count, white blood cell (WBC) count, plasma sodium (Na(+)) and potassium (K(+)). Animals with black coat colour had the highest (P < 0.05) mean values of 38.92 ± 0.03 °C, 65.09 ± 1.06 breaths/min, 81.35 ± 0.78 beats/min, 1.70 ± 0.01 for RT, RR, PR and heat stress index (HSI), respectively, followed by brown mouflon and brown with extensive white, while the Badger Face coloured sheep had the least mean values. There were significant (P < 0.05) differences between male and female sheep for RT, RR, PR and HSI. Season had a significant (P < 0.05) effect on RT, RR, PR and HSI. Coat colour and sex also significantly (P < 0.01) affected RBC, WBC, Na(+) and K(+). Seasonal variation (P < 0.05) in all the blood parameters was observed, with the exception of PCV. Interaction effect of coat colour and sex was significant (P < 0.05) on RT and HSI. Correlation coefficients among the measured traits ranged from positive to negative values. These results indicate that selection of white-coloured sheep to attenuate heat stress is desirable in the hot humid tropics. PMID:22639037

  1. Nutrients intake, performance and nitrogen balance of West African dwarf sheep fed graded levels of toasted Enterolobium cyclocarpum seeds as supplement to Panicum maximum.

    PubMed

    Idowu, O J; Arigbede, O M; Dele, P A; Olanite, J A; Adelusi, O O; Ojo, V O A; Sunmola, A S

    2013-12-01

    A study was conducted to assess the nutritive value of Enterolobium cyclocarpum seeds as supplementary feed for ruminant animals during the dry season when grasses are either not available or of low quality. Matured fruits of E. cyclocarpum were collected, toasted, peeled and then used for the trial. Thirty two West African Dwarf (WAD) sheep aged between 12 +/- 2 months with an average body weight of 10 +/- 2 kg were used in assessing the nutritive value of graded levels of toasted Enterolobium cyclocarpum seed in a concentrate diets as supplement to Panicum maximum basal diet. The percent compositions of the experimental diets were toasted E. cyclocarpum seeds at various levels of inclusion (0, 10, 20 and 30%) for diets 1, 2, 3 and 4. respectively. The diets (1-4) were consecutively fed to each animal at 50 g kg(-1) b.wt. for 12 weeks in a completely randomized design. Parameters taken were weekly body weights, daily feed intake, nutrient utilization and nitrogen balance status for each animal. Diet 2 had the highest significant (p < 0.05) nutrients intake being 871.88, 137.13, 147.59, 33.26 and 69.86 g day(-1) for DM, CP, CF, EE and ASH respectively. The Dry Matter Digestibility (DMD) coefficients decreased significantly (p < 0.05) with increased inclusion levels of toasted E. cyclocarpum seeds supplementation. Sheep fed diet 4 had the lowest feed conversion ratio (8.61) and the highest daily average gain of 58.93 g. However the animals fed Diet 2 had the highest nitrogen retension and converted their feed to flesh.

  2. Factors associated with early introduction of formula and/or solid, semi-solid or soft foods in seven Francophone West African countries.

    PubMed

    Issaka, Abukari I; Agho, Kingsley E; Page, Andrew N; Burns, Penelope L; Stevens, Garry J; Dibley, Michael J

    2015-01-30

    The aim of this study was to identify factors associated with early introduction of formula and/or solid, semi-solid or soft foods to infants aged three to five months in seven Francophone West African countries. The sources of data for the analyses were the most recent Demographic and Health Survey datasets of the seven countries, namely Benin (BDHS, 2012), Burkina Faso (BFDHS, 2010), Cote d'Ivoire (CIDHS, 2011-2012), Guinea (GDHS, 2012), Mali (MDHS, 2012-2013), Niger (NDHS, 2012) and Senegal (SDHS, 2010). The study used multiple logistic regression methods to analyse the factors associated with early introduction of complementary feeding using individual-, household- and community-level determinants. The sample was composed of 4158 infants aged between three and five months with: 671 from Benin, 811 from Burkina Faso, 362 from Cote d'Ivoire, 398 from Guinea, 519 from Mali, 767 from Niger and 630 from Senegal. Multiple analyses indicated that in three of the seven countries (Benin, Guinea and Senegal), infants who suffered illnesses, such as diarrhoea and acute respiratory infection, were significantly more likely to be introduced to formula and/or solid, semi-solid or soft foods between the age of three and five months. Other significant factors included infants who: were born in second to fourth position (Benin), whose mothers did not attend any antenatal clinics (Burkina Faso and Niger), were male (Cote d'Ivoire and Senegal), lived in an urban areas (Senegal), or were delivered by traditional birth attendants (Guinea, Niger and Senegal). Programmes to discourage early introduction of formula and/or solid, semi-solid or soft foods in these countries should target the most vulnerable segments of the population in order to improve exclusive breastfeeding practices and reduce infant mortality.

  3. Feeding potential of cassava (Manihot esculenta Crantz) peels ensiled with Leucaena leucocephala and Gliricidia sepium assessed with West African dwarf goats.

    PubMed

    Oduguwa, Bamidele Omonuwa; Oni, Adebayo Olusoji; Arigbede, Oluwasanmi Moses; Adesunbola, Julius Olukunle; Sudekum, Karl Heinz

    2013-08-01

    Cassava peels (CaPe) were ensiled in mixtures with Gliricidia sepium and Leucaena leucocephala, and the utilization of the mixed silages by West African dwarf (WAD) goats was assessed. Five silages were composed, comprising of 100% ensiled CaPe (control), CaPe + G. sepium 2:1 (w/w; 2CGS), CaPe + G. sepium 1:1 (w/w; CGS), CaPe + L. leucocephala 2:1 (w/w; 2CLL) and CaPe + L. leucocephala 1:1 (w/w; CLL). All diets were supplemented with molasses (40 g/kg) before ensiling which lasted 3 months. Fifteen WAD goats (8.01 ± 0.12 kg body weight) were fed one of the experimental diets (50 g/kg body weight) for 8 weeks. The control had the lowest hydrocyanic acid content (0.05 mg/kg DM), while others ranged from 6.2 to 81.3 mg/kg. Condensed tannin concentration ranged from 1.7 to 8.4 mg/kg DM, while mimosine levels were 11.6 and 12.4 mg/kg DM in 2CLL and CLL, respectively. After fermentation, all silages showed low pH (<4.5) and were different (P < 0.05) in the lactic, acetic and butyric acid concentrations. Ratio of foliage supplementation influenced DM intake (P < 0.05). Daily weight gains ranged from 17 (CLL) to 24 g/day in control. The digestibility coefficients of nutrients and fibre fractions differed (P < 0.05) among diets. The values for packed cell volume, haemoglobin, red blood cells, neutrophils, lymphocytes and monocytes were also different (P < 0.05) across the dietary treatments. Ensiling CaPe with foliages of G. sepium and L. leucocephala can be recommended for feeding WAD goats especially during the dry spells when there is little or no available forage for the animals. PMID:23397521

  4. Feeding potential of cassava (Manihot esculenta Crantz) peels ensiled with Leucaena leucocephala and Gliricidia sepium assessed with West African dwarf goats.

    PubMed

    Oduguwa, Bamidele Omonuwa; Oni, Adebayo Olusoji; Arigbede, Oluwasanmi Moses; Adesunbola, Julius Olukunle; Sudekum, Karl Heinz

    2013-08-01

    Cassava peels (CaPe) were ensiled in mixtures with Gliricidia sepium and Leucaena leucocephala, and the utilization of the mixed silages by West African dwarf (WAD) goats was assessed. Five silages were composed, comprising of 100% ensiled CaPe (control), CaPe + G. sepium 2:1 (w/w; 2CGS), CaPe + G. sepium 1:1 (w/w; CGS), CaPe + L. leucocephala 2:1 (w/w; 2CLL) and CaPe + L. leucocephala 1:1 (w/w; CLL). All diets were supplemented with molasses (40 g/kg) before ensiling which lasted 3 months. Fifteen WAD goats (8.01 ± 0.12 kg body weight) were fed one of the experimental diets (50 g/kg body weight) for 8 weeks. The control had the lowest hydrocyanic acid content (0.05 mg/kg DM), while others ranged from 6.2 to 81.3 mg/kg. Condensed tannin concentration ranged from 1.7 to 8.4 mg/kg DM, while mimosine levels were 11.6 and 12.4 mg/kg DM in 2CLL and CLL, respectively. After fermentation, all silages showed low pH (<4.5) and were different (P < 0.05) in the lactic, acetic and butyric acid concentrations. Ratio of foliage supplementation influenced DM intake (P < 0.05). Daily weight gains ranged from 17 (CLL) to 24 g/day in control. The digestibility coefficients of nutrients and fibre fractions differed (P < 0.05) among diets. The values for packed cell volume, haemoglobin, red blood cells, neutrophils, lymphocytes and monocytes were also different (P < 0.05) across the dietary treatments. Ensiling CaPe with foliages of G. sepium and L. leucocephala can be recommended for feeding WAD goats especially during the dry spells when there is little or no available forage for the animals.

  5. Factors Associated with Early Introduction of Formula and/or Solid, Semi-Solid or Soft Foods in Seven Francophone West African Countries

    PubMed Central

    Issaka, Abukari I.; Agho, Kingsley E.; Page, Andrew N.; Burns, Penelope L.; Stevens, Garry J.; Dibley, Michael J.

    2015-01-01

    The aim of this study was to identify factors associated with early introduction of formula and/or solid, semi-solid or soft foods to infants aged three to five months in seven Francophone West African countries. The sources of data for the analyses were the most recent Demographic and Health Survey datasets of the seven countries, namely Benin (BDHS, 2012), Burkina Faso (BFDHS, 2010), Cote d’Ivoire (CIDHS, 2011–2012), Guinea (GDHS, 2012), Mali (MDHS, 2012–2013), Niger (NDHS, 2012) and Senegal (SDHS, 2010). The study used multiple logistic regression methods to analyse the factors associated with early introduction of complementary feeding using individual-, household- and community-level determinants. The sample was composed of 4158 infants aged between three and five months with: 671 from Benin, 811 from Burkina Faso, 362 from Cote d’Ivoire, 398 from Guinea, 519 from Mali, 767 from Niger and 630 from Senegal. Multiple analyses indicated that in three of the seven countries (Benin, Guinea and Senegal), infants who suffered illnesses, such as diarrhoea and acute respiratory infection, were significantly more likely to be introduced to formula and/or solid, semi-solid or soft foods between the age of three and five months. Other significant factors included infants who: were born in second to fourth position (Benin), whose mothers did not attend any antenatal clinics (Burkina Faso and Niger), were male (Cote d’Ivoire and Senegal), lived in an urban areas (Senegal), or were delivered by traditional birth attendants (Guinea, Niger and Senegal). Programmes to discourage early introduction of formula and/or solid, semi-solid or soft foods in these countries should target the most vulnerable segments of the population in order to improve exclusive breastfeeding practices and reduce infant mortality. PMID:25647663

  6. Genetic Diversity of the Hepatitis B Virus Strains in Cuba: Absence of West-African Genotypes despite the Transatlantic Slave Trade.

    PubMed

    Rodríguez Lay, Licel A; Corredor, Marité B; Villalba, Maria C; Frómeta, Susel S; Wong, Meilin S; Valdes, Lidunka; Samada, Marcia; Sausy, Aurélie; Hübschen, Judith M; Muller, Claude P

    2015-01-01

    Cuba is an HBsAg low-prevalence country with a high coverage of anti-hepatitis B vaccine. Its population is essentially the result of the population mix of Spanish descendants and former African slaves. Information about genetic characteristics of hepatitis B virus (HBV) strains circulating in the country is scarce. The HBV genotypes/subgenotypes, serotypes, mixed infections, and S gene mutations of 172 Cuban HBsAg and HBV-DNA positive patients were determined by direct sequencing and phylogenetic analysis. Phylogenetic analysis of HBV S gene sequences showed a predominance of genotype A (92.4%), subgenotype A2 (84.9%) and A1 (7.6%). Genotype D (7.0%) and subgenotype C1 (0.6%) were also detected but typical (sub)genotypes of contemporary West-Africa (E, A3) were conspicuously absent. All genotype A, D, and C strains exhibited sequence characteristics of the adw2, ayw2, and adrq serotypes, respectively. Thirty-three (19.1%) patients showed single, double, or multiple point mutations inside the Major Hydrophilic domain associated with vaccine escape; eighteen (10.5%) patients had mutations in the T-cell epitope (amino acids 28-51), and there were another 111 point mutations downstream of the S gene. One patient had an HBV A1/A2 mixed infection. This first genetic study of Cuban HBV viruses revealed only strains that were interspersed with strains from particularly Europe, America, and Asia. The absence of genotype E supports previous hypotheses about an only recent introduction of this genotype into the general population in Africa. The presence of well-known vaccine escape (3.5%) and viral resistance mutants (2.9%) warrants strain surveillance to guide vaccination and treatment strategies.

  7. Addressing diarrhea prevalence in the West African Middle Belt: social and geographic dimensions in a case study for Benin

    PubMed Central

    Pande, Saket; Keyzer, Michiel A; Arouna, Aminou; Sonneveld, Ben GJS

    2008-01-01

    Background In West Africa, the Northern Sahelian zone and the coastal areas are densely populated but the Middle Belt in between is in general sparsely settled. Predictions of climate change foresee more frequent drought in the north and more frequent flooding in the coastal areas, while conditions in the Middle Belt will remain moderate. Consequently, the Middle Belt might become a major area for immigration but there may be constraining factors as well, particularly with respect to water availability. As a case study, the paper looks into the capacity of the Middle Belt zone of Benin, known as the Oueme River Basin (ORB), to reduce diarrhea prevalence. In Benin it links to the Millennium Development Goals on child mortality and environmental sustainability that are currently farthest from realization. However, diarrhea prevalence is only in part due to lack of availability of drinking water from a safe source. Social factors such as hygienic practices and poor sanitation are also at play. Furthermore, we consider these factors to possess the properties of a local public good that suffers from under provision and requires collective action, as individual actions to prevent illness are bound to fail as long as others free ride. Methods Combining data from the Demographic Health Survey with various spatial data sets for Benin, we apply mixed effect logit regression to arrive at a spatially explicit assessment of geographical and social determinants of diarrhea prevalence. Starting from an analysis of these factors separately at national level, we identify relevant proxies at household level, estimate a function with geo-referenced independent variables and apply it to evaluate the costs and impacts of improving access to good water in the basin. Results First, the study confirms the well established stylized fact on the causes of diarrhea that a household with access to clean water and with good hygienic practices will, irrespective of other conditions, not suffer

  8. Assessing the impact of climate change on water resources in a tropical West African catchment using an ensemble of CORDEX climate simulations (Dano, Burkina Faso)

    NASA Astrophysics Data System (ADS)

    Yira, Yacouba; Diekkrüger, Bernd; Steup, Gero; Yaovi Bossa, Aymar

    2016-04-01

    This study assesses the potential impact of climate change on water resources in the Dano catchment (Burkina Faso, West Africa). There is now essential consensus on the importance of performing multi (climate)-model assessments in order to estimate the response of the West African climate to global change. Taking advantage of the results of the COordinated Regional climate Downscaling Experiment (CORDEX-Africa) project, this study evaluates climate change impacts on water resources using an ensemble of six Regional Climate Models (RCMs) in a catchment that is potentially vulnerable to climate change and presents a low adaptive capacity. The ensemble of RCMs was first evaluated to get an estimate of the historical simulated rainfall for the catchment by comparing RCM-based simulated historical rainfall to the observed rainfall data provided by the National Meteorological Service (DGM). In general, the simulated historical rainfall agrees within some degree of variability with the observed rainfall in regard to the mean annual cycle of precipitation. However, significant biases such as a double-peaked rainy season as well as the timing of the rainy season were exhibited by individual RCMs. A statistical bias correction (Quantile mapping) was then applied to the RCM-based simulated daily rainfall for the overlapping period of 1971-2000. The results confirm the effectiveness of the applied bias correction method for rainfall. Temperature and bias corrected rainfall data from the ensemble of RCMs was used as input for the Water flow and balance Simulation Model (WaSiM) to simulate river discharge, soil moisture, evapotranspiration and groundwater depth. To take into account the concern of the potential alteration of the climate change signal due to bias correction, uncorrected climate data for a single RCM was also applied to the hydrological model. The simulated hydrological variables show a similar behavior under observed and bias corrected climate data for the

  9. Teaching a Foreign Language to the West African Student: An Examination of the Linguistic Problem with Special Reference to French Phonology.

    ERIC Educational Resources Information Center

    Kwofie, Emmanuel N.

    This monograph discusses the linguistic problems posed by the teaching and learning of non-African languages in multilingual African situations. Chapter 1 identifies and discusses the linguistic problems of foreign language education. Chapter 2 examines (1) the nature of linguistic descriptions, (2) the assumptions underlying contrastive analysis…

  10. Early upper digestive tract side effects of zidovudine with tenofovir plus emtricitabine in West African adults with high CD4 counts

    PubMed Central

    Ouattara, Eric; Danel, Christine; Moh, Raoul; Gabillard, Delphine; Peytavin, Gilles; Konan, Romuald; Carrou, Jérome Le; Bohoussou, Franck; Eholie, Serge P; Anglaret, Xavier

    2013-01-01

    Introduction Tenofovir (TDF) with emtricitabine (FTC) and zidovudine (ZDV) is a recognized alternate first-line antiretroviral (ART) regimen for patients who cannot start treatment with non-nucleoside reverse transcriptase inhibitors (NNRTIs). Clinical studies comparing TDF+FTC+ZDV to other regimens are lacking. Methods Participants in a trial of early ART in Côte d'Ivoire (Temprano ANRS 12136) started treatment with TDF/FTC plus either efavirenz (EFV) or ZDV (HIV-1+2 dually infected patients and women refusing contraception or previously treated with nevirapine). We compared rates of upper digestive serious adverse events (sAEs) between TDF/FTC+EFV and TDF/FTC+ZDV patients during the first six months of treatment. sAEs were defined as either grade 3–4 AEs or persistent grade 1–2 AEs leading to drug discontinuation. Results A total of 197 patients (76% women, median CD4 count 395/mm3) started therapy with TDF/FTC, 126 with EFV and 71 with ZDV. During the first six months of ART, 94 patients had digestive AEs (nausea/vomiting) of any grade (EFV 36/126, 29%; ZDV 58/71, 82%, p<0.0001), including 20 sAEs (EFV 3/126, 5%; ZDV 17/71, 24%, p<0.0001). In-patients on TDF/FTC+ZDV with digestive AEs, the median time to the first symptom was two days (IQR: 1–4). Plasma ZDV (Cmax) distributions and pill ZDV dosages were normal. Patients with digestive AEs had higher haemoglobin levels and tended to have higher body mass indices and more frequent past histories of cotrimoxazole (CTX) prophylaxis. Conclusions We observed an unexpectedly high rate of digestive sAEs in West African adults, mostly women, who started a 3-nuc ART with TDF/FTC+ZDV in Côte d'Ivoire. These adults were participating in a trial of early ART and had much higher CD4 counts than those who currently routinely start ART in sub-Saharan Africa. They all received CTX concomitantly with ZDV. We suggest that further early prescriptions of TDF+XTC+ZDV should be carefully monitored and that whenever possible

  11. Influence of an experimental Trypanosoma congolense infection and plane of nutrition on milk production and some biochemical parameters in West African Dwarf goats.

    PubMed

    Faye, Déthié; Fall, Abdou; Leak, Stephen; Losson, Bertrand; Geerts, Stanny

    2005-03-01

    The interactions of trypanosomosis and plane of nutrition on health and productivity of multiparous and primiparous West African Dwarf (WAD) does were studied in a multi-factorial experiment including diet (supplementation or basal diet) and infection (infected or control). Experimental does were infected with Trypanosoma congolense at the beginning of the second week post-kidding and monitored for 16 weeks after infection. Trypanosome infection significantly reduced packed cell volume (PCV) (control: 30.1+/-0.3% versus infected: 22.2+/-0.3%; P<0.0001). Regardless of infection, the drop in PCV from the pre-infection period to the end of the experiment was more severe in animals under restricted diet (interaction dietxperiod, P<0.001). Trypanosome parasitaemia tended to be higher in the supplemented group than in the basal diet group (P>0.05) and multiparous animals had a higher parasitaemia (score: 2.6+/-0.1) than primiparous animals (score: 2.2+/-0.1) (P<0.05). Trypanosome infection as well as dietary supplement had a significant effect on lactation length. Milk off-take from trypanosome-infected does was significantly lower than that from the uninfected control group (17.5+/-3.2l versus 35.5+/-3.2l, P<0.001) and there was a positive effect of plane of nutrition (supplemented: 32.8+/-3.2l and basal diet: 20.2+/-3.5l, P=0.01). The drop in milk off-take due to trypanosome infection was more severe in the supplemented group (control: 46.7+/-4.7l versus infected: 18.9+/-4.2l) than in the group receiving a basal diet (control: 24.2+/-5.0l versus infected: 16.1+/-4.7l) (interaction infectionxdiet, P=0.04) due to the number of does from the supplemented group that were withdrawn from the experiment. The effect of trypanosome infection on doe's live-weight was only noticeable during the first 8 weeks of lactation and there was no significant effect on offspring growth rate unless the mother died. Plasma total protein (TP), albumin and cholesterol concentrations were

  12. Behavioural interactions between West African dwarf nanny goats and their single-born kids during the first 48 hours post-partum.

    PubMed

    Addae; Awotwi; Oppong-Anane; Oddoye

    2000-03-22

    West African dwarf nanny goats and their single-born kids were tested to find out their behavioural response to separation and their mutual recognition during the first 48 h post-partum. The tests were conducted at 18, 24, 36 or 48 h post partum. Chi-square analyses were used to determine whether age, sex and birth weight of kids as well as h partum and parity of dams had an effect on post-partum bahaviours.In a preliminary study where the kids were not prevented from sucking prior to the tests, the majority of kids (93%) and does (86%) exhibited apparant minimal concern to separation (i.e., had scores of less than 3) and also failed to seek each other. When the kids were prevented from sucking 2 h prior to the tests, the couple showed some response to separation and made attempts to seek each other. This suggests that in goats the state of the neonate's nourishment and the fullness of the dam's udder may be important factors that determine the willingness of the kid and the dam to seek each other when separated. The behavioural response of 48-h-old kids to separation from their dams when they had not sucked for 2 h was significantly higher (P<0.05) than that of 18-h-old kids. The sex and birth-weight of 48-h-old kids did not affect their response to separation from their dams. Hours post-partum and parity of does did not affect their response to separation from their kids even though the proportion of does exhibiting the highest response was much higher in primiparous then multiparous animals (44% vs. 13%). Recognition of dams by kids was poor at 18 and 24 h with more than half (71%) the kids failing to recognize their dams. Dam recognition ability improved with age and at 48 h the majority of kids (88%) were able to recognize their dams. Does tested at 48 h post partum had better (P0.05) kid recognition than those tested at 18 and 24 h. The sex and birth weight of kids and the parity of dams had no effect on the mutual recognition of kids and their dams at 48 h

  13. Behavioural interactions between West African dwarf nanny goats and their twin-born kids during the first 48 h post-partum.

    PubMed

    Awotwi; Oppong-Anane; Addae; Oddoye

    2000-07-01

    West African dwarf nanny goats and their twin-born kids were tested to determine their behavioural response to separation and their mutual recognition during the first 48 h post-partum. Does and their kids were given scores ranging from 1 to 5, depending on how they performed in the tests. Animals that showed maximum response and recognition ability were given a score of 5, while those with minimum response and recognition ability scored 1. The kids were prevented from sucking 2 h prior to the tests, which were carried out at 18, 24, 36 and 48 h post-partum. Chi-square procedure was used to determine whether age, sex and birthweight of kids as well as hours post-partum and parity of dams had any effect on these post-partum behaviours. Out of 48 twin-born kids tested, 32 (67%) responded actively to separation from dams (i.e. had scores of 3 or more). The age, sex and birthweight of kids did not significantly affect (P>0.05) their response to separation from their dams. The hours post-partum and the parity of does also did not affect their response to separation from their kids. The dam recognition ability of twin-born kids was very poor. Out of a total of 48 kids tested, only 17 (35%) were able to recognize their dams (i.e. had scores of 3 or more). Even at 36 h, only four out of 14 (26%) could recognize their dams. It was only at 48 h that the majority of kids tested (i.e. 75%) successfully identified their dams. At 48 h, the dam recognition ability of kids was significantly better (P<0.05) than that of 18-h-old kids. Sex and birthweight of 24-48-h-old twin-born kids did not significantly affect (P>0.05) their ability to recognize their dams. The majority of does tested (i.e. 20 out of 24) were able to recognize their twin-born kids. The hour post-partum and parity of does did not significantly affect (P>0.05) their kid recognition ability.

  14. Salinity-related variation in gene expression in wild populations of the black-chinned tilapia from various West African coastal marine, estuarine and freshwater habitats

    NASA Astrophysics Data System (ADS)

    Tine, Mbaye; McKenzie, David J.; Bonhomme, François; Durand, Jean-Dominique

    2011-01-01

    This study measured the relative expression of the genes coding for Na +, K +-ATPase 1α(NAKA), voltage-dependent anion channel (VDAC), cytochrome c oxidase-1 (COX), and NADH dehydrogenase (NDH), in gills of six wild populations of a West African tilapia species, acclimatised to a range of seasonal (rainy or dry) salinities in coastal, estuarine and freshwater sites. Previous laboratory experiments have demonstrated that these genes, involved in active ion transport, oxidative phosphorylation, and intra-cellular ATP transport, are relatively over-expressed in gill tissues of this species acclimated to high salinity. Positive correlations between relative expression and ambient salinity were found for all genes in the wild populations (Spearman rank correlation, p < 0.05), although for some genes these were only significant in either the rainy season or dry season. Most significantly, however, relative expression was positively correlated amongst the four genes, indicating that they are functionally interrelated in adaptation of Sarotherodon melanotheron to salinity variations in its natural environment. In the rainy season, when salinity was unstable and ranged between zero and 37 psu across the sites, overall mean expression of the genes was higher than in the dry season, which may have reflected more variable particularly sudden fluctuations in salinity and poorer overall water quality. In the dry season, when the salinity is more stable but ranged between zero and 100 psu across the sites, NAKA, NDH and VDAC expression revealed U-shaped relationships with lowest relative expression at salinities approaching seawater, between 25 and 45 psu. Although it is not simple to establish direct relationship between gene expression levels and energy requirement for osmoregulation, these results may indicate that costs of adaptation to salinity are lowest in seawater, the natural environment of this species. While S. melanotheron can colonise environments with extremely

  15. Tropical convective systems life cycle characteristics from geostationary satellite and precipitating estimates derived from TRMM and ground weather radar observations for the West African and South American regions

    NASA Astrophysics Data System (ADS)

    Fiolleau, T.; Roca, R.; Angelis, F. C.; Viltard, N.

    2012-12-01

    In the tropics most of the rainfall comes in the form of individual storm events embedded in the synoptic circulations (e.g., monsoons). Understanding the rainfall and its variability hence requires to document these highly contributing tropical convective systems (MCS). Our knowledge of the MCS life cycle, from a physical point of view mainly arises from individual observational campaigns heavily based on ground radar observations. While this large part of observations enabled the creation of conceptual models of MCS life cycle, it nevertheless does not reach any statistically significant integrated perspective yet. To overcome this limitation, a composite technique, that will serve as a Day-1 algorithm for the Megha-Tropiques mission, is considered in this study. this method is based on a collocation in space and time of the level-2 rainfall estimates (BRAIN) derived from the TMI radiometer onboard TRMM with the cloud systems identified by a new MCS tracking algorithm called TOOCAN and based on a 3-dimensional segmentation (image + time) of the geostationary IR imagery. To complete this study, a similar method is also developed collocating the cloud systems with the precipitating features derived from the ground weather radar which has been deployed during the CHUVA campaign over several Brazilian regions from 2010 up to now. A comparison of the MCSs life cycle is then performed for the 2010-2012 summer seasons over the West African, and South American regions. On the whole region of study, the results show that the temporal evolution of the cold cloud shield associated to MCSs describes a symmetry between the growth and the decay phases. It is also shown that the parameters of the conceptual model of MCSs are strongly correlated, reducing thereby the problem to a single degree of freedom. At the system scale, over both land and oceanic regions, rainfall is described by an increase at the beginning (the first third) of the life cycle and then smoothly decreases

  16. Incidence of serious morbidity in HIV-infected adults on antiretroviral therapy in a West African care centre, 2003-2008

    PubMed Central

    2013-01-01

    Background In resource-limited settings, scaling-up antiretroviral treatment (ART) has required the involvement of decentralized health facilities with limited equipment. We estimated the incidence of serious morbidity among HIV-infected adults receiving ART in one of these HIV routine care center in sub-Saharan Africa. Methods We conducted a prospective study at the Centre Medical de Suivi des Donneurs de Sang (CMSDS), which is affiliated with the National Centre for Blood Transfusion in Abidjan, Côte d’Ivoire. Adult patients infected with HIV-1 or HIV-1/HIV-2 who initiated ART between January 2003 and December 2008 were eligible for the study. Standardized clinical data were collected at each visit. Serious morbidity was defined as a new episode of malaria, WHO stage 3–4 event, ANRS grade 3–4 adverse event, or any event leading to death or to hospitalization. Results 1008 adults, 67% women, with a median age of 35 years, and a median pre-ART CD4 count of 186/mm3 started ART and were followed for a median of 17.3 months. The overall incidences of loss to follow-up, death, and attrition were 6.2/100 person-years (PY) [95% CI 5.1-7.2], 2.3/100 PY [95% CI 1.6-2.9], and 8.1/100 PY [95% CI 7.0-9.4], respectively. The incidence of first serious event was 11.5/100 PY overall, 15.9/100 PY within the first year and 8.3/100 PY thereafter. The most frequently documented specific diagnoses were malaria, tuberculosis, bacterial septicemia and bacterial pneumonia. Conclusion Among HIV-infected adults followed in routine conditions in a West African primary care clinic, we recorded a high incidence of serious morbidity during the first year on ART. Providing care centers with diagnostic tools and standardizing data collection are necessary steps to improve the quality of care in primary care facilities in sub-Saharan Africa. PMID:24373303

  17. Biogeochemical trace gas and oxygen concentration signatures from the West African upwelling areas as observed at the Cape Verde Atmospheric Observatory (CVAO)

    NASA Astrophysics Data System (ADS)

    Kozlova, E.; Fiedler, B.; Leppert, R.; Seifert, T.; Neves, L.; Heimann, M.

    2011-12-01

    We present 3-year records of atmospheric concentrations of trace gases (CO2, CH4, CO, N2O, and SF6), and oxygen at the Cape Verde Atmospheric Observatory (CVAO). The Observatory is located on Sao Vicente Island in the north-eastern subtropical Atlantic (16.86° N, 24.87° W), and was first established within the frame of the Surface Ocean Lower Atmosphere project (SOLAS). The air is sampled from a 30-m tower. The analytical system is automated and samples air continuously (16 min for every O2 and CO2 measurement and 12 min for the rest of the species (Kozlova and Manning, 2009)). In addition, air flask samples are collected biweekly and subsequently analyzed at the Max-Planck Institute for Biogeochemistry. The Cape Verde Atmospheric Observatory is located in the North Atlantic trade wind system. We analyse the composition of marine boundary layer air masses that often have passed over the coastal upwelling areas off the coast of Western Sahara and Mauritania. These upwelling waters are supersaturated in CO2, CH4, and partly in N2O, and undersaturated in oxygen. Small shifts in the wind trajectories are reflected in synoptic variations of the atmospheric concentrations depending on the travel time of the air mass over the upwelling region. Using a footprint analysis with an atmospheric backtrajectory model, we analyse and quantify the integrated contribution of surface ocean gas exchange from these areas. We can place bounds on the gas exchange coefficient in the upwelling area by combining the flux estimates with in situ measurements of dissolved surface ocean oxygen from autonomous gliders (taken as part of the SOPRAN project) and remotely sensed ocean chlorophyll data (ocean color). The location of the Observatory provides a unique opportunity for monitoring long-term changes in spatially integrated marine productivity and oxygen depletion in the upwelling area of the West African Coast. Kozlova, E. A., and A. C. Manning, Methodology and calibration for

  18. Host Immune Responses Differ between M. africanum- and M. tuberculosis-Infected Patients following Standard Anti-tuberculosis Treatment

    PubMed Central

    Tientcheu, Leopold D.; Haks, Mariëlle C.; Agbla, Schadrac C.; Sutherland, Jayne S.; Adetifa, Ifedayo M.; Donkor, Simon; Quinten, Edwin; Daramy, Mohammed; Antonio, Martin; Kampmann, Beate; Ottenhoff, Tom H. M.; Dockrell, Hazel M.; Ota, Martin O.

    2016-01-01

    Epidemiological differences exist between Mycobacterium africanum (Maf)- and Mycobacterium tuberculosis (Mtb)-infected patients, but to date, contributing host factors have not been characterised. We analysed clinical outcomes, as well as soluble markers and gene expression profiles in unstimulated, and ESAT6/CFP-10-, whole-Maf- and Mtb-stimulated blood samples of 26 Maf- and 49 Mtb-HIV-negative tuberculosis patients before, and after 2 and 6 months of anti-tuberculosis therapy. Before treatment, both groups had similar clinical parameters, but differed in few cytokines concentration and gene expression profiles. Following treatment the body mass index, skinfold thickness and chest X-ray scores showed greater improvement in the Mtb- compared to Maf-infected patients, after adjusting for age, sex and ethnicity (p = 0.02; 0.04 and 0.007, respectively). In addition, in unstimulated blood, IL-12p70, IL12A and TLR9 were significantly higher in Maf-infected patients, while IL-15, IL-8 and MIP-1α were higher in Mtb-infected patients. Overnight stimulation with ESAT-6/CFP-10 induced significantly higher levels of IFN-γ and TNF-α production, as well as gene expression of CCL4, IL1B and TLR4 in Mtb- compared to Maf-infected patients. Our study confirms differences in clinical features and immune genes expression and concentration of proteins associated with inflammatory processes between Mtb- and Maf-infected patients following anti-tuberculosis treatment These findings have public health implications for treatment regimens, and biomarkers for tuberculosis diagnosis and susceptibility. PMID:27192147

  19. Evaluation of the Antibacterial and Antifungal Potential of Peltophorum africanum: Toxicological Effect on Human Chang Liver Cell Line

    PubMed Central

    Okeleye, Benjamin I.; Mkwetshana, Noxolo T.; Ndip, Roland N.

    2013-01-01

    We assessed the in vitro antimicrobial activity of Peltophorum africanum by means of the agar well and macrodilution methods. The toxicity on a normal human liver cell (Chang liver cell) was determined using the CellTiter-Blue cell viability assay, and the compounds contained in the fractions were identified using GC-MS. Zone diameter of inhibition of the extract ranged from 12.5 ± 0.7  to  32 ± 2.8 mm for bacteria and from  7.5 ± 0.7  to  26.4 ± 3.4 mm for yeast. Marked activity of the extract was observed against Plesiomonas shigelloides ATCC 51903, with MIC and MLC values of 0.15625 and 0.3125 mg/mL, respectively. The extract was both bactericidal (MICindex ≤ 2) and bacteriostatic/fungistatic (MICindex > 2) in activity. Lethal dose at 50 (LD50) showed 82.64 ± 1.40 degree of toxicity at 24 hrs, and 95 percentile of cell death dose activity ranged from log 3.12 ± 0.01  to  4.59 ± 0.03. The activity of the eight fractions tested ranged from 1.0 ± 0.5  to  3.7 ± 1.6 mg/mL (IC50) and from  2.1 ± 0.8  to  6.25 ± 0 mg/mL (IC90). The extract was toxic to human Chang liver cell lines. PMID:23576909

  20. Effects of supplementing cassava peels with cassava leaves and cowpea haulms on the performance, intake, digestibility and nitrogen utilization of West African Dwarf goats.

    PubMed

    Abatan, Oluwayemisi; Oni, Adebayo Olusoji; Adebayo, Kolawole; Iposu, Shamusideen; Sowande, Olusiji Sunday; Onwuka, Chryss Friday Ijeoma

    2015-01-01

    A 16-week experiment was conducted to determine the utilization of ratios of cassava leaf meal, cassava peel and cowpea haulms by West African Dwarf (WAD) goats. Thirty WAD bucks aged 8 ± 1.3 months with body weights of 6-6.5 ± 0.12 kg were divided into five groups of six animals and each group randomly assigned to one of the treatments in a completely randomized design. The five dietary treatments were formulated to contain cassava peels, leaves and cowpea haulms at different proportions of 700:100:175 (T1), 500:200:275 (T2), 300:300:375 (T3) and 100:400:475 (T4) g/kg dry matter (DM), respectively. A standard diet formulated to meet the nutrient requirement of the animals with no cassava and cowpea haulms was used as the control diet (T5). DM intake ranged from 316.16 to 458.73 g/day and significantly increased (linear (L), quadratic (Q), cubic (C): P < 0.05) as the inclusion of cassava peels reduced and cassava leaves and cowpea haulms increased in the diets. The crude protein (CP) intake significantly increased (L, Q, C: P < 0.05) as the inclusion of cassava peels reduced and cassava leaves and cowpea haulms increased in the diets. Growth rate values significantly (L: P < 0.05; Q: P < 0.01) ranged from 21.55 g/day in T1 to 43.09 g/day in T4. The feed conversion ratio was significantly (L, Q: P <0.01) lowest in T4 (11.35) and was highest in animals in T5 (14.33). Dry matter digestibility significantly (L, Q, C: P < 0.05) ranged from 78.94 to 89.52 %. The digestibility increased as the inclusion of cassava leaves and cowpea haulms increased and reduced cassava peels in the diets. The highest N intake of 14.75 g/day obtained in T4 was significantly (L: P < 0.01; Q, C: P < 0.05) different from the values of 9.26, 10.56, 11.31 and 12.02 in T1, T2, T3 and T5, respectively. Nitrogen balance values significantly (L, Q, C: P < 0.05) ranged from 2.75 g/day in T1 to 9.15 g/day in T4. It is recommended that cassava peels, leaves and

  1. A General Survey of Religious Concepts and Art of North, East, South, and West Africa.

    ERIC Educational Resources Information Center

    Stewart, Rohn

    This paper, a summary of a multi-carousel slide presentation, reviews literature on the cultures, religions, and art of African people. Before focusing on West Africa, highlights of the lifestyles, religions, and icons of non-maskmaking cultures of North, West and South African people are presented. Clarification of West African religious concepts…

  2. In vitro determination of the anti-aging potential of four southern African medicinal plants

    PubMed Central

    2013-01-01

    Background Aging is an inevitable process for all living organisms. During this process reactive oxygen species generation is increased which leads to the activation of hyaluronidase, collagenase and elastase, which can further contribute to skin aging. Four southern African medicinal plants; Clerodendrum glabrum, Schotia brachypetala, Psychotria capensis and Peltophorum africanum, were investigated to assess their anti-aging properties. Methods Anti-elastase, anti-collagenase and anti-hyaluronidase activities of twenty-eight samples, consisting of methanol and ethyl acetate extracts of the four plants, were determined using spectrophotometric methods. Radical scavenging activity was determined by the ability of the plant extracts to scavenge the ABTS•+ radical. Results The majority of the samples in the anti-elastase assay and nine in the anti-collagenase assay showed more than 80% inhibition. The ethyl acetate extract of S. brachypetala bark and leaves of P. capensis inhibited elastase activity by more than 90%. The methanol extract of S. brachypetala bark contained the highest anti-hyaluronidase activity (75.13 ± 7.49%) whilst the ethyl acetate extract of P. africanum bark exhibited the highest antioxidant activity (IC50: 1.99 ± 0.23 μg/ml). Conclusion The free radical scavenging activity and enzyme inhibitory activity of the plant extracts investigated suggests that they can help restore skin elasticity and thereby slow the wrinkling process. P. africanum was the plant with the most promising activity and will be subjected to further testing and isolation of the active compound/s. PMID:24188320

  3. Global Health Security: The Lessons from the West African Ebola Virus Disease Epidemic and MERS Outbreak in the Republic of Korea.

    PubMed

    Ghsa Preparation Task Force Team

    2015-12-01

    The Ebola virus disease outbreak in West Africa and the Middle East Respiratory Syndrome outbreak in the Republic of Korea have given huge impacts in different aspects. Health security is no more a new coinage. Global health security became more realistic in its practical application. In the perspective of global health, it will be helpful to peruse lessons learned from the Ebola outbreak in West Africa and MERS outbreak in Korea. PMID:27429901

  4. Ancestral links of Chesapeake Bay region African Americans to specific Bight of Bonny (West Africa) microethnic groups and increased frequency of aggressive breast cancer in both regions.

    PubMed

    Jackson, Fatimah L C

    2008-01-01

    The high frequency of aggressive, early onset, and highly fatal breast cancer among Chesapeake Bay region African Americans suggests that there may be a contributing ancestral component. This study identifies the region's founding African, European, and Native American Indian populations using ethnogenetic layering and identifies the microethnic substructure of each founding continental aggregate. The largest component (38%) of the enslaved Africans brought to the Chesapeake Bay originally came from the coastal and hinterlands of the Bight of Bonny, a region with very high rates of aggressive, early onset breast cancer. Ethnogenetic layering is applied a second time to reveal the microethnic groups of the Bight of Bonny hinterlands with historical links to the Chesapeake Bay region. These analyses identify the specific microethnic groups within this region of Africa that may be the sources of relevant polymorphisms contributing to the etiology of aggressive breast cancer in the Chesapeake Bay. This report suggests a historical link between specific African microethnic groups and a US health disparity.

  5. Structure and presumptive function of the iridocorneal angle of the West Indian manatee (Trichechus manatus), short-finned pilot whale (Globicephala macrorhynchus), hippopotamus (Hippopotamus amphibius), and African elephant (Loxodonta africana).

    PubMed

    Hatfield, Jessie R; Samuelson, Don A; Lewis, Patricia A; Chisholm, Mae

    2003-03-01

    The iridocorneal angles of prepared eyes from the West Indian manatee, short-finned pilot whale, hippopotamus and African elephant were examined and compared using light microscopy. The manatee and pilot whale demonstrated capacity for a large amount of aqueous outflow, probably as part of a system compensating for lack of ciliary musculature, and possibly also related to environmental changes associated with life at varying depths. The elephant angle displayed many characteristics of large herbivores, but was found to have relatively low capacity for aqueous outflow via both primary and secondary routes. The hippopotamus shared characteristics with both land- and water-dwelling mammals; uveoscleral aqueous outflow may be substantial as in the marine mammals, but the angular aqueous plexus was less extensive and a robust pectinate ligament was present. The angles varied greatly in size and composition among the four species, and most structures were found to be uniquely suited to the habitat of each animal.

  6. Structure and presumptive function of the iridocorneal angle of the West Indian manatee (Trichechus manatus), short-finned pilot whale (Globicephala macrorhynchus), hippopotamus (Hippopotamus amphibius), and African elephant (Loxodonta africana).

    PubMed

    Hatfield, Jessie R; Samuelson, Don A; Lewis, Patricia A; Chisholm, Mae

    2003-03-01

    The iridocorneal angles of prepared eyes from the West Indian manatee, short-finned pilot whale, hippopotamus and African elephant were examined and compared using light microscopy. The manatee and pilot whale demonstrated capacity for a large amount of aqueous outflow, probably as part of a system compensating for lack of ciliary musculature, and possibly also related to environmental changes associated with life at varying depths. The elephant angle displayed many characteristics of large herbivores, but was found to have relatively low capacity for aqueous outflow via both primary and secondary routes. The hippopotamus shared characteristics with both land- and water-dwelling mammals; uveoscleral aqueous outflow may be substantial as in the marine mammals, but the angular aqueous plexus was less extensive and a robust pectinate ligament was present. The angles varied greatly in size and composition among the four species, and most structures were found to be uniquely suited to the habitat of each animal. PMID:12641841

  7. Investigation the efficiency of various methods of volatile oil extraction from Trichodesma africanum and their impact on the antioxidant and antimicrobial activities

    PubMed Central

    Jaradat, Nidal Amin; Zaid, Abdel Naser; Abuzant, Aladdin; Shawahna, Ramzi

    2016-01-01

    Background: Currently, there is an increasing interest in developing more efficient techniques for the extraction of phytochemicals. Microwaves and ultrasonic extraction methods are promising techniques that can be used for this purpose. Objectives: The purpose of this study was to investigate the impact of different extraction methods on yield, antioxidant and antimicrobial activities of volatile oil extracted from Trichodesma africanum. Materials and Methods: Volatile oil was extracted using microwave, ultrasonic, microwave-ultrasonic, and conventional hydrodistillation methods. The extracted oil was evaluated for antioxidant and antimicrobial activities. The antioxidant activity was assessed by 2,2-Diphenyl-1-picrylhydrazyl scavenging assay, whereas the antimicrobial activity was assessed by broth microdilution method. The antimicrobial activity of the volatile oils was examined against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa American type culture collection reference strains, as well as against methicillin-resistant S. aureus (MRSA) and Candida albicans clinical isolates. Results: The volatile oil obtained by the four extraction methods in this study exhibited both antioxidant and antimicrobial activities. Among the four extraction methods used, the microwave-ultrasonic method yielded the largest amount (1.8% v/w) and the yield exhibited the highest antioxidant activity in terms of inhibition (91.83% ± 1.1). The minimum inhibitory concentrations for E. coli, P. aeruginosa, S. aureus, MRSA, and C. albicans were 3, 5, 6, 3, and 9, respectively. Conclusion: Among the extraction techniques used in this study, the microwave-ultrasonic method showed the best results. Moreover, this study suggests that T. africanum volatile oils contain active substances that could potentially be used both as natural preservatives in food and pharmaceutical industries as well as in developing new antimicrobial and antioxidant agents. PMID:27366351

  8. A First-Language-First Multilingual Model to Meet the Quality Imperative in Formal Basic Education in Three "Francophone" West African Countries

    ERIC Educational Resources Information Center

    Nikiema, Norbert

    2011-01-01

    This paper documents the new trend towards a first-language-first multilingual model in formal education in three former French colonies of West Africa, namely Burkina Faso, Mali and Niger. It compares the sociolinguistic situations, the conditions of the development of multilingual education and the achievements of mother-tongue-medium education…

  9. Genomes of Two Chronological Isolates (Helicobacter pylori 2017 and 2018) of the West African Helicobacter pylori Strain 908 Obtained from a Single Patient▿

    PubMed Central

    Avasthi, Tiruvayipati Suma; Devi, Singamaneni Haritha; Taylor, Todd D.; Kumar, Narender; Baddam, Ramani; Kondo, Shinji; Suzuki, Yutaka; Lamouliatte, Hervé; Mégraud, Francis; Ahmed, Niyaz

    2011-01-01

    The diverse clinical outcomes of colonization by Helicobacter pylori reflect the need to understand the genomic rearrangements enabling the bacterium to adapt to host niches and exhibit varied colonization/virulence potential. We describe the genome sequences of the two serial isolates, H. pylori 2017 and 2018 (the chronological subclones of H. pylori 908), cultured in 2003 from the antrum and corpus, respectively, of an African patient who suffered from recrudescent duodenal ulcer disease. When compared with the genome of the parent strain, 908 (isolated from the antrum of the same patient in 1994), the genome sequences revealed genomic alterations relevant to virulence optimization or host-specific adaptation. PMID:21515762

  10. HLA-E coding and 3' untranslated region variability determined by next-generation sequencing in two West-African population samples.

    PubMed

    Castelli, Erick C; Mendes-Junior, Celso T; Sabbagh, Audrey; Porto, Iane O P; Garcia, André; Ramalho, Jaqueline; Lima, Thálitta H A; Massaro, Juliana D; Dias, Fabrício C; Collares, Cristhianna V A; Jamonneau, Vincent; Bucheton, Bruno; Camara, Mamadou; Donadi, Eduardo A

    2015-12-01

    HLA-E is a non-classical Human Leucocyte Antigen class I gene with immunomodulatory properties. Whereas HLA-E expression usually occurs at low levels, it is widely distributed amongst human tissues, has the ability to bind self and non-self antigens and to interact with NK cells and T lymphocytes, being important for immunosurveillance and also for fighting against infections. HLA-E is usually the most conserved locus among all class I genes. However, most of the previous studies evaluating HLA-E variability sequenced only a few exons or genotyped known polymorphisms. Here we report a strategy to evaluate HLA-E variability by next-generation sequencing (NGS) that might be used to other HLA loci and present the HLA-E haplotype diversity considering the segment encoding the entire HLA-E mRNA (including 5'UTR, introns and the 3'UTR) in two African population samples, Susu from Guinea-Conakry and Lobi from Burkina Faso. Our results indicate that (a) the HLA-E gene is indeed conserved, encoding mainly two different protein molecules; (b) Africans do present several unknown HLA-E alleles presenting synonymous mutations; (c) the HLA-E 3'UTR is quite polymorphic and (d) haplotypes in the HLA-E 3'UTR are in close association with HLA-E coding alleles. NGS has proved to be an important tool on data generation for future studies evaluating variability in non-classical MHC genes.

  11. The molecular determination of HLA-Cw alleles in the Mandenka (West Africa) reveals a close genetic relationship between Africans and Europeans.

    PubMed

    Sanchez-Mazas, A; Steiner, Q G; Grundschober, C; Tiercy, J M

    2000-10-01

    HLA-Cw alleles were determined by high-resolution polymerase chain reaction-sequence-specific oligonucleotide probe (PCR-SSOP) oligotyping in a sample of 165 Mandenka, a population from Eastern Senegal previously analysed for A/B and DRB/DQB polymorphisms. A total of 18 Cw alleles were identified, with Cw*0401/5 and 1601 accounting for a combined frequency of 36%. A comparison of Cw allele frequencies among several populations of different origins, Mandenka, Swiss, English, Ashkenazi Jews from the UK and Japanese, reveals a high genetic heterogeneity among them, but also a much closer relationship between Mandenka, Europeans and Ashkenazi than between any of these populations and Japanese. Cw*0501, Cw*0701 and Cw*1601, among others, appear to be restricted to the European and African populations. Many B-Cw haplotypes exhibit a significant linkage disequilibrium in the Mandenka, among which B*3501-Cw*0401 and B*7801-Cw*1601, formed by the most frequent B and Cw alleles, and B*5201-Cw*1601, B*5702-Cw*18 and B*4410-Cw*0401, not yet observed in other populations. B*3501-Cw*0401 is found with similar frequencies in Europeans. The results possibly support a close historical relationship between Africans and Europeans as compared to East Asiatics. However, the HLA-Cw frequency distributions are characterised by an excess of heterozygotes, indicating that balancing selection may have played a role in the evolution of this polymorphism.

  12. The importance of baobab (Adansonia digitata L.) in rural West African subsistence--suggestion of a cautionary approach to international market export of baobab fruits.

    PubMed

    Buchmann, Christine; Prehsler, Sarah; Hartl, Anna; Vogl, Christian R

    2010-01-01

    The European Commission recently authorized the import of baobab (Adansonia digitata L.) fruit pulp as a novel food. In rural West Africa the multipurpose baobab is used extensively for subsistence. Three hundred traditional uses of the baobab were documented in Benin, Mali, and Senegal across 11 ethnic groups and 4 agroecological zones. Baobab fruits and leaves are consumed throughout the year. The export of baobab fruits could negatively influence livelihoods, including reduced nutritional intake, change of power relations, and access rights. Capacity building and certification could encourage a sustainable and ethical trade of baobab fruits without neglecting baobab use in subsistence.

  13. A first-language-first multilingual model to meet the quality imperative in formal basic education in three `francophone' West African countries

    NASA Astrophysics Data System (ADS)

    Nikièma, Norbert

    2011-12-01

    This paper documents the new trend towards a first-language-first multilingual model in formal education in three former French colonies of West Africa, namely Burkina Faso, Mali and Niger. It compares the sociolinguistic situations, the conditions of the development of multilingual education and the achievements of mother-tongue-medium education in all three countries. The evidence is that, contrary to common discourse in francophonie, a strong first-language-first model in formal education is the best guarantee of a good mastery of French and, more generally, of quality education in francophone countries.

  14. How well do land surface models reproduce the water and energy cycles in the West African monsoon system ? Evaluation over the Upper Ouémé basin, Benin (ALMIP2 project)

    NASA Astrophysics Data System (ADS)

    Peugeot, C.; Boone, A. A.; Demarty, J.; manuela, G.; Laurent, K.; Cappelaere, B.; Awessou, B.; Cohard, J.; Galle, S.; Gascon, T.; Getirana, A.; Hector, B.; Mamadou, O.; Richard, A.; Seghieri, J.; Séguis, L.

    2013-12-01

    Land surface models (LSMs) are widely used in environmental and climate sciences to simulate matter (water, carbon) and energy exchanges between the continental surface and the atmosphere. They are also increasingly used in a wide range of applications such as impact studies on land use management or climate change. The AMMA project and the associated observation campaigns provided unique data-sets to drive land surface models and to evaluate their results over the West African region, where such high added-value information has been lacking. In the framework of the ALMIP2 project (AMMA Land surface Model Inter-comparison Project - phase 2), simulations from about 20 LSMs were done on three contrasted meso-scale domains in Mali, Niger and Benin, over the period 2005-2008 using the same forcing data sets at 0.05 degree and 30 minutes space-time resolution. This talk analyses the simulated water and energy budget components on the sub-humid upper Ouémé basin (10,000 km2, Benin site), where the high-quality rainfall and runoff datasets allow a detailed and original hydrological evaluation of these meso-scale simulations. As expected, the model inter-comparison shows large differences in the water and energy partitioning, either at the annual (see figure) or intra-seasonal time scale. Most of them do not reproduce the observed runoff, with annual biases ranging from -100% to 200 %. The multi-model mean Evapotranspiration (ET) correctly matches the observations, specially in the rainy season, with contrasted simulations of evaporation vs. transpiration from one model to the other. The identification of the more realistic water and energy partitioning is a key issue addressed by the ALMIP2 project. Previous studies performed in the AMMA framework on the Oueme basin highlighted the key role of below-ground water dynamics in the hydrological cycle (lateral transfer to rivers, groundwater seasonal recharge-discharge, ...). Moreover, field evidences suggested that

  15. Trace gas emissions to the atmosphere by biomass burning in the west African savannas. Final report, 1 October 1991-31 March 1994

    SciTech Connect

    Frouin, R.J.; Iacobellis, S.F.; Razafimpanilo, H.; Somerville, R.C.J.

    1994-08-01

    Savanna fires and atmospheric carbon dioxide (CO2) detection and estimating burned area using Advanced Very High Resolution Radiometer (AVHRR) reflectance data are investigated in this two part research project. The first part involves carbon dioxide flux estimates and a three-dimensional transport model to quantify the effect of North African savanna fires on atmospheric CO2 concentration, including CO2 spatial and temporal variability patterns and their significance to global emissions. The second article describes two methods used to determine burned area from AVHRR data. The article discusses the relationship between the percentage of burned area and AVHRR channel 2 reflectance (the linear method) and Normalized Difference Vegetation Index (NDVI) (the nonlinear method). A comparative performance analysis of each method is described.

  16. Usefulness of Noninvasive Predictors of Oesophageal Varices in Black African Cirrhotic Patients in Côte d'Ivoire (West Africa)

    PubMed Central

    Mahassadi, Alassan Kouamé; Bathaix, Fulgence Yao; Assi, Constant; Bangoura, Aboubacar Demba; Allah-Kouadio, Emile; Kissi, Henriette Ya; Touré, Abdoulaye; Doffou, Stanislas; Konaté, Issa; Attia, Alain Koffi; Camara, Mathieu Benoit; Ndri-Yoman, Thérèse Aya

    2012-01-01

    Aims. To determine the usefulness of platelet count (PC), spleen diameter (SD) and platelet count/spleen diameter ratio (PC/SD ratio) for the prediction of oesophageal varices (OV) and large OV in black African patients with cirrhosis in Côte d'Ivoire. Materials and Methods. Study was conducted in a training sample (111 patients) and in a validation sample (91 patients). Results. Factors predicting OV were sex: (OR = 0.08, P = 0.0003), PC (OR = 12.4, P = 0.0003), SD (OR = 1.04, P = 0.002) in the training sample. The AUROCs (±SE) of the model (cutoff ≥ 0.6), PC (cutoff < 110500), SD (cutoff > 140) and PC/SD ratio (cutoff ≤ 868) were, respectively; 0.879 ± 0.04, 0.768 ± 0.06, 0.679 ± 0.06, 0.793 ± 0.06. For the prediction of large OV, the model's AUROC (0.850 ± 0.05) was superior to that of PC (0.688 ± 0.06), SD (0.732 ± 0.05) and PC/SD ratio (0.752 ± 0.06). In the validation sample, with PC, PC/SD ratio and the model, upper digestive endoscopy could be obviated respectively in 45.1, 45.1, and 44% of cirrhotic patients. Prophylactic treatment with beta blockers could be started undoubtedly respectively in 36.3, 41.8 and 28.6% of them as having large OV. Conclusion. Non-invasive means could be used to monitor cirrhotic patients and consider treatment in African regions lacking endoscopic facilities. PMID:22888334

  17. Vector Competence of Aedes aegypti and Aedes vittatus (Diptera: Culicidae) from Senegal and Cape Verde Archipelago for West African Lineages of Chikungunya Virus

    PubMed Central

    Diagne, Cheikh T.; Faye, Oumar; Guerbois, Mathilde; Knight, Rachel; Diallo, Diawo; Faye, Ousmane; Ba, Yamar; Dia, Ibrahima; Faye, Ousmane; Weaver, Scott C.; Sall, Amadou A.; Diallo, Mawlouth

    2014-01-01

    To assess the risk of emergence of chikungunya virus (CHIKV) in West Africa, vector competence of wild-type, urban, and non-urban Aedes aegypti and Ae. vittatus from Senegal and Cape Verde for CHIKV was investigated. Mosquitoes were fed orally with CHIKV isolates from mosquitoes (ArD30237), bats (CS13-288), and humans (HD180738). After 5, 10, and 15 days of incubation following an infectious blood meal, presence of CHIKV RNA was determined in bodies, legs/wings, and saliva using real-time reverse transcription–polymerase chain reaction. Aedes vittatus showed high susceptibility (50–100%) and early dissemination and transmission of all CHIKV strains tested. Aedes aegypti exhibited infection rates ranging from 0% to 50%. Aedes aegypti from Cape Verde and Kedougou, but not those from Dakar, showed the potential to transmit CHIKV in saliva. Analysis of biology and competence showed relatively high infective survival rates for Ae. vittatus and Ae. aegypti from Cape Verde, suggesting their efficient vector capacity in West Africa. PMID:25002293

  18. Vector competence of Aedes aegypti and Aedes vittatus (Diptera: Culicidae) from Senegal and Cape Verde archipelago for West African lineages of chikungunya virus.

    PubMed

    Diagne, Cheikh T; Faye, Oumar; Guerbois, Mathilde; Knight, Rachel; Diallo, Diawo; Faye, Ousmane; Ba, Yamar; Dia, Ibrahima; Faye, Ousmane; Weaver, Scott C; Sall, Amadou A; Diallo, Mawlouth

    2014-09-01

    To assess the risk of emergence of chikungunya virus (CHIKV) in West Africa, vector competence of wild-type, urban, and non-urban Aedes aegypti and Ae. vittatus from Senegal and Cape Verde for CHIKV was investigated. Mosquitoes were fed orally with CHIKV isolates from mosquitoes (ArD30237), bats (CS13-288), and humans (HD180738). After 5, 10, and 15 days of incubation following an infectious blood meal, presence of CHIKV RNA was determined in bodies, legs/wings, and saliva using real-time reverse transcription-polymerase chain reaction. Aedes vittatus showed high susceptibility (50-100%) and early dissemination and transmission of all CHIKV strains tested. Aedes aegypti exhibited infection rates ranging from 0% to 50%. Aedes aegypti from Cape Verde and Kedougou, but not those from Dakar, showed the potential to transmit CHIKV in saliva. Analysis of biology and competence showed relatively high infective survival rates for Ae. vittatus and Ae. aegypti from Cape Verde, suggesting their efficient vector capacity in West Africa. PMID:25002293

  19. International employees' concerns during serious disease outbreaks and the potential impact on business continuity: Lessons identified from the 2014-15 West African Ebola outbreak.

    PubMed

    Cole, Jennifer; Watkins, Chris

    This paper presents the findings of research carried out into the information-seeking behaviour, and information requirements of a small sample of international workers stationed in West Africa during the Zaire Ebola virus outbreak of 2014-15. The research study under which these results were obtained was part of exploratory research for a PhD focused on the use, and potential uses, of social media platforms during serious disease outbreaks that might be used to inform policy planning for public health and emergency response interventions. Thus, the findings from this study may provide valuable insights to business continuity managers and emergency planners in making future decisions about information exchange and crisis decision-making during future serious disease outbreaks. PMID:26642172

  20. International employees' concerns during serious disease outbreaks and the potential impact on business continuity: Lessons identified from the 2014-15 West African Ebola outbreak.

    PubMed

    Cole, Jennifer; Watkins, Chris

    This paper presents the findings of research carried out into the information-seeking behaviour, and information requirements of a small sample of international workers stationed in West Africa during the Zaire Ebola virus outbreak of 2014-15. The research study under which these results were obtained was part of exploratory research for a PhD focused on the use, and potential uses, of social media platforms during serious disease outbreaks that might be used to inform policy planning for public health and emergency response interventions. Thus, the findings from this study may provide valuable insights to business continuity managers and emergency planners in making future decisions about information exchange and crisis decision-making during future serious disease outbreaks.

  1. /sup 40/Ar//sup 39/Ar age of detrital muscovite within Lower Ordovician sandstone in the coastal plain basement of Florida: implications for west African terrane linkages

    SciTech Connect

    Dallmeyer, R.D.

    1987-11-01

    Detrital muscovite was concentrated from a core of Lower Ordovician sandstone recovered from 1282 m in the Sun Oil Company, H.T. Parker No.1 well, Marion County, Florida. The concentrate records a /sup 40/Ar//sup 39/Ar plateau age of 504.1 +/- 2.1 Ma. The Paleozoic sedimentary section penetrated in this well is part of an extensive subsurface Lower Ordovician-Middle Devonian sedimentary succession characterized by Gondwanan paleontological affinities. The succession has been correlated with sequences of similar age in the Bove Basin of west Africa which unconformably overlie metamorphic units of the Bassaride and Rokelide orogens in Senegal and Guinea. Muscovite within these metamorphic rocks records ca. 500-510 Ma postmetamorphic /sup 40/Ar//sup 39/Ar cooling ages and was likely a proximal source for the lower Paleozoic clastic detritus represented in the pre-Mesozoic sedimentary sequences beneath the southeastern US coastal plain.

  2. Relationships between deformation and magmatism in the Pan-African Kandi Shear Zone: Microstructural and AMS studies of Ediacaran granitoid intrusions in central Bénin (West Africa)

    NASA Astrophysics Data System (ADS)

    Adissin Glodji, L.; Bascou, J.; Yessoufou, S.; Ménot, R.-P.; Villaros, A.

    2014-09-01

    Relationships between the metamorphic basement, granitic intrusions and the Kandi Shear Zone (KSZ) in central Bénin have been investigated using petrological and structural approaches, in order to better understand the space and time parameters of the Pan-African shear deformation and the Ediacaran magmatism. In central Bénin, metamorphic rocks from the KSZ display a steep to vertical N-S trending foliation, a sub-horizontal mineral lineation together with kinematic indicators in agreement with a dextral transcurrent mega-shear zone. Four granitic intrusions (Dassa, Tré, Gobada and Tchetti) show many petrological similarities. They are biotite ± amphibole - ilmenite ± magnetite monzogranites with ferrous and metaluminous I-type features derived from high-K calk-alkaline magma. A fifth intrusion (Fita) is an alkali-feldspar, biotite, magnetite and ilmenite bearing granite crystallized from an alkaline magma. Moreover, high K2O, Zr, Y, Nb and low CaO, MgO and Al2O3 contents together with high (FeOt/MgO) and low LIL/HFS elements ratios suggesting an A-type granite affinity. Microstructural and AMS investigations presented in this paper show (i) solid-state deformation evidence for Dassa pluton and (ii) a magmatic deformation for the Tré, Tchetti, Gobada and Fita granitoids. Foliation in Dassa is parallel to the mesoscopic planar mylonitic foliation of the metamorphic basement. In the Tré, Tchetti, Gobada and Fita granitoids, magmatic textures and magnetic fabrics are coherent with the KSZ activity. These data suggest (i) a syn-kinematic nature for most of the intrusions (Tré, Gobada, Tchetti and Fita), except Dassa which correspond to an earlier event (ii) the succession of high-K calk-alkaline (Dassa, Tré, Gobada, Tchetti) evolves toward alkaline magmas (Fita) during the KSZ strike-slip tectonics. These observations highlight the changing nature of magma composition, magmatic processes and the different sources during KSZ activity in the Bénin Nigerian

  3. Dry deposition of nitrogen compounds (NO2, HNO3, NH3), sulfur dioxide and ozone in West and Central African ecosystems using the inferential method

    NASA Astrophysics Data System (ADS)

    Adon, M.; Galy-Lacaux, C.; Yoboue, V.; Delon, C.; Solmon, F.; Kaptue Tchuente, A. T.

    2013-05-01

    This work is part of the IDAF program (IGAC-DEBITS-AFRICA) and is based on the long term monitoring of gas concentrations (1998-2007) established on seven remote sites representative of major African ecosystems. Dry deposition fluxes were estimated by the inferential method using on one hand surface measurements of gas concentrations (NO2, HNO3, NH3, SO2, and O3) and on the other hand simulated dry deposition velocities (Vd). Vd were calculated using the big-leaf model of Zhang et al. (2003b). In the model of deposition, surface and meteorological conditions specific to IDAF sites have been adapted in order to simulate Vd representative of major African ecosystems. The monthly, seasonal and annual mean variations of gaseous dry deposition fluxes (NO2, HNO3, NH3, O3, and SO2) are analyzed. Along the latitudinal transect of ecosystems, the annual mean dry deposition fluxes of nitrogen compounds range from 0.4 ± 0.0 to 0.8 ± 0.2 kg N ha-1 yr-1 for NO2, from 0.7 ± 0.1 to 1.0 ± 0.3 kg N ha-1 yr-1 for HNO3, and from 2.3 ± 0.8 to 10.5 ± 5.0 kg N ha-1 yr-1 for NH3 over the study period (1998-2007). The total nitrogen dry deposition flux (NO2+HNO3+NH3) is more important in forests (11.2-11.8 kg N ha-1 yr-1) than in wet and dry savannas (3.4-5.3 kg N ha-1 yr-1). NH3 dominated nitrogen dry deposition, representing 67-80% of the total. The annual mean dry deposition fluxes of ozone range between 11.3 ± 4.7 and 17.5 ± 3.0 kg ha-1 yr-1 in dry savannas, 17.5 ± 3.0 and 19.2 ± 2.9 kg ha-1 yr-1 in wet savannas, and 10.6 ± 2.0 and 13.2 ± 3.6 kg ha-1 yr-1 in forests. Lowest O3 dry deposition fluxes in forests are correlated to low measured O3 concentrations, lower of a factor of 2-3, compared to others ecosystems. Along the ecosystem transect, annual mean of SO2 dry deposition fluxes present low values and a small variability (0.5 to 1 kg S ha-1 yr-1). No specific trend in the interannual variability of these gaseous dry deposition fluxes is observed over the study period.

  4. Problems of Transition for African Students in an American University.

    ERIC Educational Resources Information Center

    Adelegan, Francis O.; Parks, David J.

    1985-01-01

    Surveyed Black East African, Black West African and Arabic North African students (N=33) enrolled in an American university to identify their problems and personal attributes and environmental conditions influencing their experience. Discusses social, transportation, food, loneliness, and other problems. (MCF)

  5. Structure and petrology of Pan-African nepheline syenites from the South West Cameroon; Implications for their emplacement mode, petrogenesis and geodynamic significance

    NASA Astrophysics Data System (ADS)

    Emmanuel, Nsifa Nkonguin; Rigobert, Tchameni; Anne, Nédélec; Roberto, Siqueira; André, Pouclet; Jérôme, Bascou

    2013-11-01

    Three late-Neoproterozoic nepheline syenite intrusions crop out close to the late-Pan-African SW Cameroon shear zone, namely the Mont des Eléphants, Eboundja and Rocher du Loup intrusions. They are characterized by magmatic to solid-state deformation structures and microstructures. Their magmas were mainly derived from partial melting of the subcontinental lithospheric mantle. Magmatic differentiation may have occurred through fractionation of clinopyroxene, amphibole, plagioclase and accessory minerals (apatite, sphene, magnetite and zircon). Bulk magnetic susceptibilities are variable in intensity depending of the magnetite content. Their magnetic anisotropies are unusally high, especially in the Rocher du Loup intrusion. The trajectories of magnetic foliations and lineations display an arcuate shape from an E-W direction in the easternmost Mont des Eléphants to a N-S direction in the Rocher du Loup intrusion. These features are consistent with a synkinematic emplacement in relation with the sinistral motion along the SW Cameroon shear zone, whose age is therefore dated by the age of the syenites, i.e. 590 Ma. Magma genesis and ascent was likely favored by a large gradient in lithospheric thickness along the western margin of the Congo craton.

  6. Host acceptance, suitability, and effects of host deprivation on the West African egg parasitoid Telenomus isis (Hymenoptera: Scelionidae) reared on East African stemborers under varying temperature and relative humidity regimens.

    PubMed

    Bruce, Anani Yaovi; Schulthess, Fritz; Mueke, Jones

    2009-06-01

    Scelionid egg parasitoids of Telenomus spp. have been shown to significantly affect noctuid stemborer populations and yields of maize in western Africa. One of them, T. isis, has never been reported from eastern Africa and was introduced into the laboratories of the International Centre of Insect Physiology and Ecology, Kenya. This study evaluates the biotic potential of T. isis using East African stemborers as hosts. Host acceptance was tested using 15 lepidopteran borer species. Only noctuid stemborers were accepted for oviposition by T. isis. Sesamia calamistis Hampson, Sesamia nonagrioides (Lefebvre), and Busseola fusca (Fuller) were further used to study the effect of host species, host age, duration of host deprivation, temperature, and humidity on the performance of the parasitoid. In contrast to sex ratio, developmental time, parasitism, and parasitoid emergence varied significantly with host species, and the former two decreased with the age of host eggs. Female longevity increased with duration of host deprivation, whereas average lifetime fecundity decreased, probably because of oocyte resorption. T. isis successfully developed between 18 and 32 degrees C at both low (40-50%) and high (70-80%) relative humidity regimens, but temperature played a more critical role. Using the modified Logan model, the lower and upper temperature thresholds for development were estimated at 11.5 and 37.5 degrees C, respectively, with an optimum at 30.5 degrees C for both humidity regimens. Depending on temperature and relative humidity regimen, the intrinsic rate of increase (r(m)) varied from 0.077 to 0.300, net reproductive rate (R(o)) from 7.70 to 83.96, and generation time (G) from 11 to 38 d. The results of this study indicate that T. isis is likely to establish in eastern Africa.

  7. Rapid Accumulation of Total Lipid in Rhizoclonium africanum Kutzing as Biodiesel Feedstock under Nutrient Limitations and the Associated Changes at Cellular Level

    PubMed Central

    Satpati, Gour Gopal; Kanjilal, Sanjit; Narayana Prasad, Rachapudi Badari; Pal, Ruma

    2015-01-01

    Increase of total lipid and the proportion of the favorable fatty acids in marine green filamentous macroalga Rhizoclonium africanum (Chlorophyceae) was studied under nitrate and phosphate limitations. These stresses were given by both eliminating and doubling the required amounts of nitrate and phosphate salts in the growth media. A significant twofold increase in total lipid (193.03 mg/g) was achieved in cells in absence of nitrate in the culture medium, followed by phosphate limitation (142.65 mg/g). The intracellular accumulation of neutral lipids was observed by fluorescence microscopy. The scanning electron microscopic study showed the major structural changes under nutrient starvation. Fourier transform infrared spectroscopy (FTIR) revealed the presence of ester (C-O-C stretching), ketone (C-C stretching), carboxylic acid (O-H bending), phosphine (P-H stretching), aromatic (C-H stretching and bending), and alcohol (O-H stretching and bending) groups in the treated cells indicating the high accumulation of lipid hydrocarbons in the treated cells. Elevated levels of fatty acids favorable for biodiesel production, that is, C16:0, C16:1, C18:1, and C20:1, were identified under nitrate- and phosphate-deficient conditions. This study shows that the manipulation of cultural conditions could affect the biosynthetic pathways leading to increased lipid production while increasing the proportion of fatty acids suitable for biodiesel production. PMID:26880924

  8. Rapid Accumulation of Total Lipid in Rhizoclonium africanum Kutzing as Biodiesel Feedstock under Nutrient Limitations and the Associated Changes at Cellular Level.

    PubMed

    Satpati, Gour Gopal; Kanjilal, Sanjit; Narayana Prasad, Rachapudi Badari; Pal, Ruma

    2015-01-01

    Increase of total lipid and the proportion of the favorable fatty acids in marine green filamentous macroalga Rhizoclonium africanum (Chlorophyceae) was studied under nitrate and phosphate limitations. These stresses were given by both eliminating and doubling the required amounts of nitrate and phosphate salts in the growth media. A significant twofold increase in total lipid (193.03 mg/g) was achieved in cells in absence of nitrate in the culture medium, followed by phosphate limitation (142.65 mg/g). The intracellular accumulation of neutral lipids was observed by fluorescence microscopy. The scanning electron microscopic study showed the major structural changes under nutrient starvation. Fourier transform infrared spectroscopy (FTIR) revealed the presence of ester (C-O-C stretching), ketone (C-C stretching), carboxylic acid (O-H bending), phosphine (P-H stretching), aromatic (C-H stretching and bending), and alcohol (O-H stretching and bending) groups in the treated cells indicating the high accumulation of lipid hydrocarbons in the treated cells. Elevated levels of fatty acids favorable for biodiesel production, that is, C16:0, C16:1, C18:1, and C20:1, were identified under nitrate- and phosphate-deficient conditions. This study shows that the manipulation of cultural conditions could affect the biosynthetic pathways leading to increased lipid production while increasing the proportion of fatty acids suitable for biodiesel production.

  9. Impact of potential large-scale and medium-scale irrigation on the West African Monsoon and its dependence on location of irrigated area

    NASA Astrophysics Data System (ADS)

    Eltahir, E. A. B.; IM, E. S.

    2014-12-01

    This study investigates the impact of potential large-scale (about 400,000 km2) and medium-scale (about 60,000 km2) irrigation on the climate of West Africa using the MIT Regional Climate Model. A new irrigation module is implemented to assess the impact of location and scheduling of irrigation on rainfall distribution over West Africa. A control simulation (without irrigation) and various sensitivity experiments (with irrigation) are performed and compared to discern the effects of irrigation location, size and scheduling. In general, the irrigation-induced surface cooling due to anomalously wet soil tends to suppress moist convection and rainfall, which in turn induces local subsidence and low level anti-cyclonic circulation. These local effects are dominated by a consistent reduction of local rainfall over the irrigated land, irrespective of its location. However, the remote response of rainfall distribution to irrigation exhibits a significant sensitivity to the latitudinal position of irrigation. The low-level northeasterly flow associated with anti-cyclonic circulation centered over the irrigation area can enhance the extent of low level convergence through interaction with the prevailing monsoon flow, leading to significant increase in rainfall. Despite much reduced forcing of irrigation water, the medium-scale irrigation seems to draw the same response as large-scale irrigation, which supports the robustness of the response to irrigation in our modeling system. Both large-scale and medium-scale irrigation experiments show that an optimal irrigation location and scheduling exists that would lead to a more efficient use of irrigation water. The approach of using a regional climate model to investigate the impact of location and size of irrigation schemes may be the first step in incorporating land-atmosphere interactions in the design of location and size of irrigation projects. However, this theoretical approach is still in early stages of development and

  10. The Varved Sediments of Lake Bosumtwi, Ghana and Implications for a new Chronology of West African Hydrologic Change During the Late Quaternary

    NASA Astrophysics Data System (ADS)

    Wheeler, C. W.; Overpeck, J. T.; Beck, J. W.; Arko, J.; Sharp, W. E.

    2002-12-01

    Lake Bosumtwi is a small (8-km diameter), deep (78-m) crater lake in the lowland forest of southern Ghana (West Africa) that offers tremendous potential for high-resolution environmental reconstruction. Lying in the path of the seasonal Intertropical Convergence Zone (ITCZ) monsoonal precipitation procession, as well as the dry Harmattan winds of the Sahel in winter, this lake is uniquely located to provide potential proxy records of these dominate climatic phenomena effecting West Africa's hydrologic cycle. The lake exhibits excellent sediment preservation, with finely laminated sediments through most of the ca. 24,000 years of core material recovered thus far. We present a detailed chronological analysis of the uppermost 1.1 meters of laminated sediment, obtained via a recently collected suite of freeze- and piston-cores. Utilizing digital images and petrographic thin-section transects of six freeze-cores and two piston cores, we identified 400 diagnostic marker laminations common among the cores, thus enabling cross correlation of the cores to a sub-centimeter scale. The marker laminations also serve as anchor points for counts of organic-rich fine-laminations that were hypothesized to be annual. Excellent agreement between our lamination counts and independent radiometric sediment age models (lead-210 and bomb radiocarbon) verify that these counted laminations are in fact annual (i.e. varves). Thus, we are able to present an annual chronology for the last 800 years of sedimentation (prior to 2000 AD)ñ ~4%. Though anthroprogenic changes have probably effected the local environment within the last 100 years, as we interpret anomalous increases in %organic carbon, %inorganic carbon and %nitrogen to indicate, the varve appearance does not seem to change across the 1.1 m section analyzed. Pre-nuclear weapon testing radiocarbon values, derived from bulk organic carbon, were examined in relation to the varve and lead-210 age-models to assess radiocarbon age offset

  11. Climatic change and quasi-oscillations in central-west Argentina summer precipitation: main features and coherent behaviour with southern African region

    NASA Astrophysics Data System (ADS)

    Compagnucci, R. H.; Agosta, E. A.; Vargas, W. M.

    observed in the South African counterpart with severe characteristics, thereby continuing the quasi-18-year oscillation. Consequently, the low-frequency coherent behaviour between both the Argentine and South African regions is lost from the mid-1970s. The analysis of association of wet/dry spells and warm/cold, El Niño/La Niña episodes appears to be not significant at scales of year-to-year variability although at decadal to multi-decadal scales the association could be relevant. More than one process of multi-decadal variability of global SSTs could influence the Argentine summer rainfall region and the former bi-decadal teleconnection. Finally, potential hypothetical factors of change are discussed, such as the strengthening of direct and indirect mechanisms of moisture flux transport associated with global warming, low-level atmospheric circulation changes and/or to SSTs mean condition long-term variations over tropical and subtropical South Atlantic and South Pacific oceans.

  12. Test of validity of a dynamic soil carbon model using data from leaf litter decomposition in a West African tropical forest

    NASA Astrophysics Data System (ADS)

    Guendehou, G. H. S.; Liski, J.; Tuomi, M.; Moudachirou, M.; Sinsin, B.; Mäkipää, R.

    2013-05-01

    We evaluated the applicability of the dynamic soil carbon model Yasso07 in tropical conditions in West Africa by simulating the litter decomposition process using as required input into the model litter mass, litter quality, temperature and precipitation collected during a litterbag experiment. The experiment was conducted over a six-month period on leaf litter of five dominant tree species, namely Afzelia africana, Anogeissus leiocarpa, Ceiba pentandra, Dialium guineense and Diospyros mespiliformis in a semi-deciduous vertisol forest in Southern Benin. Since the predictions of Yasso07 were not consistent with the observations on mass loss and chemical composition of litter, Yasso07 was fitted to the dataset composed of global data and the new experimental data from Benin. The re-parameterized versions of Yasso07 had a good predictive ability and refined the applicability of the model in Benin to estimate soil carbon stocks, its changes and CO2 emissions from heterotrophic respiration as main outputs of the model. The findings of this research support the hypothesis that the high variation of litter quality observed in the tropics is a major driver of the decomposition and needs to be accounted in the model parameterization.

  13. Osmoregulatory strategies in natural populations of the black-chinned tilapia Sarotherodon melanotheron exposed to extreme salinities in West African estuaries.

    PubMed

    Lorin-Nebel, Catherine; Avarre, Jean-Christophe; Faivre, Nicolas; Wallon, Sophie; Charmantier, Guy; Durand, Jean-Dominique

    2012-08-01

    The effect of salinity was studied in natural populations of the black-chinned tilapia (Sarotherodon melanotheron) from West Africa. This euryhaline species colonizes nearly all coastal environments from bays to lagoons characterized by salinities ranging from fresh water to hypersaline water over 100 ‰. Individuals were sampled during the dry season at several locations characterized by different levels of salinity (3-102 ‰). Their osmotic status and their gills were analyzed. The branchial mitochondria-rich cells (MRC), localized at the basis of the filaments and along the lamellae in fish taken from the saline stations, showed a wide plasticity with significant differences in their number and size. The most striking results were a significant larger area (≈3x) and a higher number (≈55x) of MRC at high salinity (102 ‰) compared to low salinity (3 ‰). The major ion transporters and channels were localized by immunocytochemistry and different expression patterns have been recorded between stations. Despite an increased Na⁺/K⁺-ATPase (NKA) α-subunit expression and NKA activity, pointing to an increased monovalent ion excretion, a severe osmotic imbalance was recorded in animals living in hypersaline environments.

  14. Women’s perceptions of effects of war on intimate partner violence and gender roles in two post-conflict West African Countries: consequences and unexpected opportunities

    PubMed Central

    2014-01-01

    Background The aim of this paper is to explore women’s perceptions of the causes of intimate partner violence (IPV) in West Africa, and the ways in which they understand these causes to interact with the experiences of war. Methods The study was conducted in two locations in Sierra Leone and two in Liberia, using focus group discussions (N groups =14) and individual interviews (N = 20). Results Women perceive the causes of IPV to be linked with other difficulties faced by women in these settings, including their financial dependence on men, traditional gender expectations and social changes that took place during and after the wars in those countries. According to respondents, the wars increased the use of violence by some men, as violence became for them a normal way of responding to frustrations and challenges. However, the war also resulted in women becoming economically active, which was said by some to have decreased IPV, as the pressure on men to provide for their families reduced. Economic independence, together with services provided by NGOs, also gave women the option of leaving a violent relationship. Conclusions IPV was found to be a significant problem for women in Sierra Leone and Liberia. The interactions between war experiences and financial and cultural issues are multi-faceted and not uniformly positive or negative. PMID:25104971

  15. Comparison of multi-temporal NOAA-AVHRR and SPOT-XS satellite data for mapping land-cover dynamics in the West African Sahel

    NASA Technical Reports Server (NTRS)

    Marsh, S. E.; Walsh, J. L.; Lee, C. T.; Beck, L. R.; Hutchinson, C. F.

    1992-01-01

    Multi-resolution and multi-temporal remote sensing data (SPOT-XS and AVHRR) were evaluated for mapping local land-cover dynamics in the Sahel of West Africa. The aim of this research was to evaluate the agricultural information that could be derived from both high and low spatial resolution data in areas where there is very often limited ground information. A combination of raster-based image processing and vector-based geographical information system mapping was found to be effective for understanding both spatial and spectral land-cover dynamics. The SPOT data proved useful for mapping local land-cover classes in a dominantly recessive agricultural region. The AVHRR-LAC data could be used to map the dynamics of riparian vegetation, but not the changes associated with recession agriculture. In areas where there was a complex mixture of recession and irrigated agriculture, as well as riparian vegetation, the AVHRR data did not provide an accurate temporal assessment of vegetation dynamics.

  16. 57Fe Mössbauer spectroscopy investigations of iron oxidation states in the Harmattan dust nutrient contribution to West African soils

    NASA Astrophysics Data System (ADS)

    Adetunji, Jacob

    2014-12-01

    A variety of investigations have been carried out on Harmattan dust over many decades demonstrating the continuing importance of the Harmattan dust phenomenon. The investigations have included elemental enrichment factors, mineralogical nutrient input through dust deposition on the soil, meteorological studies, etc. Harmattan dust is important, not only for its impact on radio communication and low visibility in the shipping lanes over the Atlantic, but also on the livelihood and health of people living in countries over which the dust-laden Harmattan wind blows. However, so far, the aspect of nutrient mineral deposition on the soil has not been thoroughly investigated and requires attention, since the majority of people living in West Africa rely heavily on agriculture. It is therefore relevant to know the useful nutrients in the Harmattan dust deposited on soils of the region. This study is therefore aimed at determining the ferric-ferrous ratio of the iron-bearing minerals contained in the Harmattan dust, so their nutritional contribution can be considered. The Mössbauer technique is a powerful tool for studying the ferric-ferrous ratio and has therefore been used, for the first time, to determine the oxidation states of iron in the dust samples. The results of the analysis show that the Harmattan dust is seriously deficient in ferrous iron, which is the more soluble Fe-ion, needed in the soil for healthy crops and plants in general.

  17. Sibling species distributions of the Simulium damnosum complex in the west African Onchocerciasis Control Programme area during the decade 1984-93, following intensive larviciding since 1974.

    PubMed

    Boakye, D A; Back, C; Fiasorgbor, G K; Sib, A P; Coulibaly, Y

    1998-10-01

    During the decade from 1984 to 1993, nine species of the Simulium damnosum complex of blackflies (Diptera: Simuliidae) were identified from the area covered by the Onchocerciasis Control Programme. These were S. damnosum s.s., S. dieguerense, S. konkourense, S. leonense, S. sanctipauli, S. sirbanum, S. soubrense, S. squamosum, and S. yahense. Some of these species were found to consist of two chromosomal variant populations. These were S. konkourense 'Konkouré' and 'Menankaya' forms, S. sanctipauli sensu stricto and 'Djodji' form, S. soubrense 'Chute Milo' and 'Beffa' forms. The distribution of these twelve cytological taxa was assessed in relation to the two main vegetation zones of West Africa (forest and savanna), topography, river size and other factors. The range of each species was influenced by seasonal climatic changes in wind movement and river water level. The most widely distributed species were S. sirbanum and S. damnosum s.s., associated with savanna areas, recorded from all river basins. Simulium dieguerense was restricted mainly to Western Mali on the Rivers Bafing and Bakoye in the Senegal River basin. Simulium squamosum was identified from rivers draining mountainous areas in both the forest and savanna zones. Simulium yahense was found in small permanent rivers along a wide forested band parallel to the coast and was absent from the plains of Togo and Benin. Members of the S. sanctipauli subcomplex had restricted distributions except for S. sanctipauli s.s., which was widespread in large rivers of the forest zone from Sierra Leone to the Volta Lake in Ghana. Simulium soubrense 'Beffa' form occurred in Togo and Benin, S. soubrense 'Chutes Milo' form in Guinea, both 'Konkouré' and 'Menankaya' forms of S. konkourense occurred predominantly in Guinea and S. leonense in Sierra Leone. The relevance of the distribution maps and the importance of the data bank to vector control larvicidal operations are discussed. PMID:9824818

  18. Importance of migrants infected with Onchocerca volvulus in west African river valleys protected by 14 to 15 years of Simulium control.

    PubMed

    De Sole, G; Remme, J

    1991-06-01

    A study was done to determine the importance of human migration from non-controlled endemic onchocerciasis foci to the river valleys that have been protected for the past 14 to 15 years by the vector control operations of the Onchocerciasis Control Programme in West Africa. The aim of the study was to assess the contribution of migrants to the prevalence and intensity of infection in villages from 5 major river valleys and their potential role in causing relapse of transmission once the vector is allowed to return. In Burkina Faso the migrant population varied from 0.0% to 18.1% of the village population, and averaged 4.9%. Migrants accounted only for 0.6% of the population in Ghanaian and Ivorian villages along the Black Volta river. The prevalence of infection was significantly higher in migrants (8.2%) than in non migrants (1.1%) in the surveyed villages in Burkina Faso, and 1.5% of migrants had infections with more than 16 microfilariae per snip as against 0.2% of non migrants. Nearly all infected migrants came from the south of the Côte d'Ivoire. The study shows that human migration has caused the importation of Onchocerca volvulus from non-controlled areas. However, the epidemiological importance of this phenomenon is limited because of the very small number of infected migrants per village while two-third of the infected migrants are believed to be infected with the less pathogenic forest strain of the parasite. Because migration patterns changes geographically and over time similar studies will be continued on a regular basis. PMID:1654591

  19. Importance of migrants infected with Onchocerca volvulus in west African river valleys protected by 14 to 15 years of Simulium control.

    PubMed

    De Sole, G; Remme, J

    1991-06-01

    A study was done to determine the importance of human migration from non-controlled endemic onchocerciasis foci to the river valleys that have been protected for the past 14 to 15 years by the vector control operations of the Onchocerciasis Control Programme in West Africa. The aim of the study was to assess the contribution of migrants to the prevalence and intensity of infection in villages from 5 major river valleys and their potential role in causing relapse of transmission once the vector is allowed to return. In Burkina Faso the migrant population varied from 0.0% to 18.1% of the village population, and averaged 4.9%. Migrants accounted only for 0.6% of the population in Ghanaian and Ivorian villages along the Black Volta river. The prevalence of infection was significantly higher in migrants (8.2%) than in non migrants (1.1%) in the surveyed villages in Burkina Faso, and 1.5% of migrants had infections with more than 16 microfilariae per snip as against 0.2% of non migrants. Nearly all infected migrants came from the south of the Côte d'Ivoire. The study shows that human migration has caused the importation of Onchocerca volvulus from non-controlled areas. However, the epidemiological importance of this phenomenon is limited because of the very small number of infected migrants per village while two-third of the infected migrants are believed to be infected with the less pathogenic forest strain of the parasite. Because migration patterns changes geographically and over time similar studies will be continued on a regular basis.

  20. Sibling species distributions of the Simulium damnosum complex in the west African Onchocerciasis Control Programme area during the decade 1984-93, following intensive larviciding since 1974.

    PubMed

    Boakye, D A; Back, C; Fiasorgbor, G K; Sib, A P; Coulibaly, Y

    1998-10-01

    During the decade from 1984 to 1993, nine species of the Simulium damnosum complex of blackflies (Diptera: Simuliidae) were identified from the area covered by the Onchocerciasis Control Programme. These were S. damnosum s.s., S. dieguerense, S. konkourense, S. leonense, S. sanctipauli, S. sirbanum, S. soubrense, S. squamosum, and S. yahense. Some of these species were found to consist of two chromosomal variant populations. These were S. konkourense 'Konkouré' and 'Menankaya' forms, S. sanctipauli sensu stricto and 'Djodji' form, S. soubrense 'Chute Milo' and 'Beffa' forms. The distribution of these twelve cytological taxa was assessed in relation to the two main vegetation zones of West Africa (forest and savanna), topography, river size and other factors. The range of each species was influenced by seasonal climatic changes in wind movement and river water level. The most widely distributed species were S. sirbanum and S. damnosum s.s., associated with savanna areas, recorded from all river basins. Simulium dieguerense was restricted mainly to Western Mali on the Rivers Bafing and Bakoye in the Senegal River basin. Simulium squamosum was identified from rivers draining mountainous areas in both the forest and savanna zones. Simulium yahense was found in small permanent rivers along a wide forested band parallel to the coast and was absent from the plains of Togo and Benin. Members of the S. sanctipauli subcomplex had restricted distributions except for S. sanctipauli s.s., which was widespread in large rivers of the forest zone from Sierra Leone to the Volta Lake in Ghana. Simulium soubrense 'Beffa' form occurred in Togo and Benin, S. soubrense 'Chutes Milo' form in Guinea, both 'Konkouré' and 'Menankaya' forms of S. konkourense occurred predominantly in Guinea and S. leonense in Sierra Leone. The relevance of the distribution maps and the importance of the data bank to vector control larvicidal operations are discussed.

  1. Dry deposition of nitrogen compounds (NO2, HNO3, NH3), sulfur dioxide and ozone in west and central African ecosystems using the inferential method

    NASA Astrophysics Data System (ADS)

    Adon, M.; Galy-Lacaux, C.; Delon, C.; Yoboue, V.; Solmon, F.; Kaptue Tchuente, A. T.

    2013-11-01

    This work is part of the IDAF program (IGAC-DEBITS-AFRICA) and is based on the long-term monitoring of gas concentrations (1998-2007) established at seven remote sites representative of major African ecosystems. Dry deposition fluxes were estimated by the inferential method using on the one hand surface measurements of gas concentrations (NO2, HNO3, NH3, SO2 and O3) and on the other hand modeled exchange rates. Dry deposition velocities (Vd) were calculated using the big-leaf model of Zhang et al. (2003b). The bidirectional approach is used for NH3 surface-atmosphere exchange (Zhang et al., 2010). Surface and meteorological conditions specific to IDAF sites have been used in the models of deposition. The seasonal and annual mean variations of gaseous dry deposition fluxes (NO2, HNO3, NH3, O3 and SO2) are analyzed. Along the latitudinal transect of ecosystems, the annual mean dry deposition fluxes of nitrogen compounds range from -0.4 to -0.8 kg N ha-1 yr-1 for NO2, from -0.7 to -1.0 kg N ha-1 yr-1 for HNO3 and from -0.7 to -8.3 kg N ha-1 yr-1 for NH3 over the study period (1998-2007). The total nitrogen dry deposition flux (NO2+HNO3+NH3) is more important in forests (-10 kg N ha-1 yr-1) than in wet and dry savannas (-1.6 to -3.9 kg N ha-1 yr-1). The annual mean dry deposition fluxes of ozone range between -11 and -19 kg ha-1 yr-1 in dry and wet savannas, and -11 and -13 kg ha-1 yr-1 in forests. Lowest O3 dry deposition fluxes in forests are correlated to low measured O3 concentrations, lower by a factor of 2-3, compared to other ecosystems. Along the ecosystem transect, the annual mean of SO2 dry deposition fluxes presents low values and a small variability (-0.5 to -1 kg S ha-1 yr-1). No specific trend in the interannual variability of these gaseous dry deposition fluxes is observed over the study period.

  2. Liberia: America's Closest African Ally.

    ERIC Educational Resources Information Center

    Thompson, Samuel; Mowell, Barry

    1997-01-01

    Profiles Liberia, the West African nation patterned after the United States and colonized with freed U.S. slaves in the early 19th century. Reviews the country's history and its eruption into civil strife in 1990, showing how tensions have often characterized relationships between Liberians of different ethnic identities. (MJP)

  3. The prevalence of badnaviruses in West African yams (Dioscorea cayenensis-rotundata) and evidence of endogenous pararetrovirus sequences in their genomes.

    PubMed

    Seal, Susan; Turaki, Aliyu; Muller, Emmanuelle; Kumar, P Lava; Kenyon, Lawrence; Filloux, Denis; Galzi, Serge; Lopez-Montes, Antonio; Iskra-Caruana, Marie-Line

    2014-06-24

    Yam (Dioscorea spp.) is an important vegetatively-propagated staple crop in West Africa. Viruses are pervasive in yam worldwide, decreasing growth and yield, as well as hindering the international movement of germplasm. Badnaviruses have been reported to be the most prevalent in yam, and genomes of some other badnaviruses are known to be integrated in their host plant species. However, it was not clear if a similar scenario occurs in Dioscorea yam. This study was conducted to verify the prevalence of badnaviruses, and determine if badnavirus genomes are integrated in the yam genome. Leaf samples (n=58) representing eight species of yam from global yam collections kept at CIRAD, France, and 127 samples of D. rotundata breeding lines (n=112) and landraces (n=15) at IITA, Nigeria, were screened using generic badnavirus PCR primers. Positive amplification of an expected ca. 579bp fragment, corresponding to a partial RT-RNaseH region, was detected in 47 (81%) of 58 samples analysed from CIRAD collections, and 100% of the 127 IITA D. rotundata samples. All the D. cayenensis and D. rotundata samples from the CIRAD and IITA collections tested PCR-positive, and sequencing of a selection of the PCR products confirmed they were typical of the genus Badnavirus. A comparison of serological and nucleic acid techniques was used to investigate whether the PCR-positives were sequences amplified from badnavirus particles or putative endogenous badnavirus sequences in the yam genome. Protein A sandwich-enzyme-linked immunosorbent assay (PAS-ELISA) with badnavirus polyclonal antisera detected cross-reacting viral particles in only 60% (92 of 153) of the CIRAD collection samples analysed, in contrast to the aforementioned 81% by PCR. Immunosorbent electron microscopy (ISEM) of virus preparations of a select set of 16 samples, representing different combinations of positive and negative PCR and PAS-ELISA results, identified bacilliform particles in 11 of these samples. Three PCR

  4. Obtaining land cover changes information from multitemporal analysis of Landsat-TM images: results from a case study in West African dryland

    NASA Astrophysics Data System (ADS)

    Nutini, F.; Boschetti, M.; Brivio, P. A.; Antoninetti, M.

    2012-04-01

    The Sahelian belt of West Africa is a semiarid region characterized by wide climate variations, which can in turn affect the livelihood of local populations particularly in rangeland areas, as happens during the dramatic food crisis in the 70-80s caused by rainfall scarcity. The monitoring of natural resources and rainfed agricultural activities, with the aim to provide information to support Sahelian food security action, needs the production of detailed thematic maps as emphasized by several scientific papers. In this framework, a study was conducted to develop a method to exploit time series of remote sensed satellite data to 1) provide reliable land cover (LC) map at local scale in a dry region and 2) obtain a LC change (LCC) map that contribute to identify the plausible causes of local environmental instability. Satellite images used for this work consist in a time series of Landsat Thematic Mapper (TM) (path row 195-50) acquired in the 2000 (6 scenes) and 2007 (9 scenes) from February (Dry season) to September (end of wet season). The study investigates the different contribution provided by spectra information of a single Landsat TM image and by time series of derived NDVI. Different tests have been conducted with different combination of data set (spectral and temporal)in order to identify the best approach to obtain a LC map in five classes of interest: Shrubland, Cultivated Land, Water body, Herbaceous vegetation and Bare soil. The best classification approach is exposed and applied on two years in the last decade. The comparison between this two LC results in land cover change map, that displays the changes of vegetation patterns that have been characterized the area. The discussed results show a largely stable dryland region, but locally characterized by hot-spot of decreasing in natural vegetation inside the rangelands and an increasing of cultivations along fossil valleys where human activities are slightly intense. The discussion shows that this hot

  5. Research with African Americans: Lessons Learned about Recruiting African American Women

    ERIC Educational Resources Information Center

    Coker, Angela D.; Huang, Hsin-Hsin; Kashubeck-West, Susan

    2009-01-01

    The authors briefly explore literature related to recruiting African American research participants, reflect on their experiences conducting body image research with a sample of African American college women in an earlier study (S. Kashubeck-West et al., 2008), and discuss some methodological and cultural challenges that they encountered during…

  6. Effect of Age at Antiretroviral Therapy Initiation on Catch-Up Growth within the First 24 Months among HIV-Infected Children in the IeDEA West African Pediatric Cohort

    PubMed Central

    Jesson, Julie; Koumakpaï, Sikiratou; Diagne, Ndeye R.; Amorissani-Folquet, Madeleine; Kouéta, Fla; Aka, Addi; Lawson-Evi, Koko; Dicko, Fatoumata; Kouakou, Kouadio; Pety, Touré; Renner, Lorna; Eboua, Tanoh; Coffie, Patrick A.; Desmonde, Sophie; Leroy, Valériane

    2015-01-01

    Background We described malnutrition and the effect of age at antiretroviral therapy (ART) initiation on catch-up growth over 24 months among HIV-infected children enrolled in the IeDEA West African paediatric cohort (pWADA). Methods Malnutrition was defined at ART initiation (baseline) by a Z-score <-2 SD, according to three anthropometric indicators: Weight-for-age (WAZ) for underweight, Height-for-age (HAZ) for stunting, and Weight-for-Height/BMI-for-age (WHZ/BAZ) for wasting. Kaplan-Meier estimates for catch-up growth (Z-score ≥-2 SD) on ART, adjusted for gender, immunodeficiency and malnutrition at ART initiation, ART regimen, time period and country, were compared by age at ART initiation. Cox proportional hazards regression models determined predictors of catch-up growth on ART over 24 months. Results Between 2001 and 2012, 2004 HIV-infected children < 10 years of age were included. At ART initiation, 51% were underweight, 48% were stunted and 33% were wasted. The 24-month adjusted estimates for catch-up growth were 69% (95% confidence interval [CI]: 57;80), 61% (95%CI: 47;70), and 90% (95%CI: 76;95) for WAZ, HAZ, and WHZ/BAZ, respectively. Adjusted catch-up growth was more likely for children <5 years of age at ART initiation compared to children ≥5 years for WAZ, HAZ (P<0.001), and for WHZ/BAZ (P = 0.026). Conclusions Malnutrition among these children is an additional burden that has to be urgently managed. Despite a significant growth improvement after 24 months on ART, especially in children <5 years, a substantial proportion of children still never achieved catch-up growth. Nutritional care should be part of the global healthcare of HIV-infected children in sub-Saharan Africa. PMID:25955835

  7. Co-occurrence and distribution of East (L1014S) and West (L1014F) African knock-down resistance in Anopheles gambiae sensu lato population of Tanzania

    PubMed Central

    Kabula, Bilali; Kisinza, William; Tungu, Patrick; Ndege, Chacha; Batengana, Benard; Kollo, Douglas; Malima, Robert; Kafuko, Jessica; Mohamed, Mahdi; Magesa, Stephen

    2014-01-01

    Objective Insecticide resistance molecular markers can provide sensitive indicators of resistance development in Anopheles vector populations. Assaying these makers is of paramount importance in the resistance monitoring programme. We investigated the presence and distribution of knock-down resistance (kdr) mutations in Anopheles gambiae s.l. in Tanzania. Methods Indoor-resting Anopheles mosquitoes were collected from 10 sites and tested for insecticide resistance using the standard WHO protocol. Polymerase chain reaction-based molecular diagnostics were used to genotype mosquitoes and detect kdr mutations. Results The An. gambiae tested were resistance to lambdacyhalothrin in Muheza, Arumeru and Muleba. Out of 350 An. gambiae s.l. genotyped, 35% were An. gambiae s.s. and 65% An. arabiensis. L1014S and L1014F mutations were detected in both An. gambiae s.s. and An. arabiensis. L1014S point mutation was found at the allelic frequency of 4–33%, while L1014F was at the allelic frequency 6–41%. The L1014S mutation was much associated with An. gambiae s.s. (χ2 = 23.41; P < 0.0001) and L1014F associated with An. arabiensis (χ2 = 11.21; P = 0.0008). The occurrence of the L1014S allele was significantly associated with lambdacyhalothrin resistance mosquitoes (Fisher exact P < 0.001). Conclusion The observed co-occurrence of L1014S and L1014F mutations coupled with reports of insecticide resistance in the country suggest that pyrethroid resistance is becoming a widespread phenomenon among our malaria vector populations. The presence of L1014F mutation in this East African mosquito population indicates the spreading of this gene across Africa. The potential operational implications of these findings on malaria control need further exploration. Objectif Les marqueurs moléculaires de la résistance aux insecticides peuvent fournir des indicateurs sensibles du développement de la résistance dans les populations de vecteurs Anopheles. Le test de ces

  8. Charting the Ancestry of African Americans

    PubMed Central

    Salas, Antonio; Carracedo, Ángel; Richards, Martin; Macaulay, Vincent

    2005-01-01

    The Atlantic slave trade promoted by West European empires (15th–19th centuries) forcibly moved at least 11 million people from Africa, including about one-third from west-central Africa, to European and American destinations. The mitochondrial DNA (mtDNA) genome has retained an imprint of this process, but previous analyses lacked west-central African data. Here, we make use of an African database of 4,860 mtDNAs, which include 948 mtDNA sequences from west-central Africa and a further 154 from the southwest, and compare these for the first time with a publicly available database of 1,148 African Americans from the United States that contains 1,053 mtDNAs of sub-Saharan ancestry. We show that >55% of the U.S. lineages have a West African ancestry, with <41% coming from west-central or southwestern Africa. These results are remarkably similar to the most up-to-date analyses of the historical record. PMID:16175514

  9. (Im)migrations, Relations, and Identities of African Peoples: Toward an Endarkened Transnational Feminist Praxis in Education

    ERIC Educational Resources Information Center

    Okpalaoka, Chinwe L.; Dillard, Cynthia B.

    2012-01-01

    This article focuses on the sense of what an "African" (American) identity could mean when viewed through the processes of migrations and fluid identities of contemporary African immigrant children as they interact with their African (Americans) peers in schools. The purpose of this article is to use data from a study of West African immigrant…

  10. Vocational Education Processes of Yoruba Women in West Africa.

    ERIC Educational Resources Information Center

    Bawubya, Maria

    1988-01-01

    Describes traditional training methods for the occupations of Yoruba women of West Africa, such as weaving, dyeing, and pottery-making. Suggests that these vocational training methodologies could be applied to contemporary African economic problems. (SK)

  11. Is This an African I See before Me?

    ERIC Educational Resources Information Center

    Wright, Handel Kashope

    2007-01-01

    In this speech, the author uses five moments of his own existence to speak to how he thinks the West conceptualizes and depicts Africa and Africans. This involves autobiography in a sense because he used his own life, but the discussion is not about him. It is about western conceptions and representations of Africans as reflected in the following…

  12. The Principles and Content of African Traditional Education

    ERIC Educational Resources Information Center

    Adeyemi, Michael B.; Adeyinka, Augustus A.

    2003-01-01

    The type of education prevalent in Africa before the coming of Western civilisation was generally known as African traditional education or indigenous education of the various communities. Most recent works on new perspectives in African education, vis-a-vis the role and impact of Christian missions from the West include those of Coetzee and Roux…

  13. Title I: African-American Studies Program. Student Workbook.

    ERIC Educational Resources Information Center

    Wilson, Linda

    This is a student workbook in African American studies used in the Detroit, Michigan public schools in 1978-79. The workbook contains student exercises in African history, culture, geography, languages, architecture, folktales, food, and artifacts. The continent of Africa is covered in units on Egypt, North Africa, West Africa, Central Africa, and…

  14. Experiences of African American Empowerment: A Jamesian Perspective on Agency

    ERIC Educational Resources Information Center

    Curtis-Tweed, Phyllis

    2003-01-01

    This essay draws from the work of William James and three African American pragmatists, W.E.B. Du Bois, Ralph Ellison and Cornel West, to explore the moral relevance of the self as an empowered agent among African American youth. The focus is on Jamesian agency as a function of the individual's awareness of options in context, the self-empowerment…

  15. West and Central Africa.

    PubMed

    Lydie, N; Robinson, N J

    1998-01-01

    This article reviews scientific and other literature during the 1990s that links migration and mobility with the spread of sexually transmitted diseases (STDs), including HIV/AIDS. The focus is on key population groups linked to the spread of HIV and STDs in West and Central Africa: migrant laborers, truck drivers, itinerant traders, commercial sex workers (CSWs), and refugees. Countries with high emigration and immigration tend to have high levels of HIV infection, with the exception of Senegal. The main destination of immigrants are Senegal, Nigeria, and Cote d'Ivoire in West Africa and Cameroon, Congo, Gabon, and Congo in Central Africa. The risk of infection and the spread of HIV is variable among migrants. There is little in the literature that substantiates hypotheses about the strong association between migration and HIV-positive status. Information is needed on the duration, frequency of return visits, living conditions, sexual activities with multiple partners, and information before departure, along the routes, at final destination, and at the time of returns. Action-based research in five West African countries (Burkina Faso, Cote d'Ivoire, Mali, Niger, and Senegal) should produce results in late 1998. Comparable studies in Central Africa are unknown. Regional studies should be complemented by local studies. Prevention would benefit from studies on the relative size of these five population groups by geographic location.

  16. Black Identities: West Indian Immigrant Dreams and American Realities.

    ERIC Educational Resources Information Center

    Waters, Mary C.

    This study of the attitudes and status of West Indian immigrants in the United States, based on interviews with 59 West Indian immigrants, 83 adolescent and young adult children of immigrants, 27 African Americans, 25 White Americans, and 6 coworkers of immigrants shows the changes that occur as immigrants confront the realities of U.S. life. West…

  17. The Lion in West Africa Is Critically Endangered

    PubMed Central

    Henschel, Philipp; Coad, Lauren; Burton, Cole; Chataigner, Beatrice; Dunn, Andrew; MacDonald, David; Saidu, Yohanna; Hunter, Luke T. B.

    2014-01-01

    The African lion has declined to <35,000 individuals occupying 25% of its historic range. The situation is most critical for the geographically isolated populations in West Africa, where the species is considered regionally endangered. Elevating their conservation significance, recent molecular studies establish the genetic distinctiveness of West and Central African lions from other extant African populations. Interventions to save West African lions are urgently required. However formulating effective conservation strategies has been hampered by a lack of data on the species' current distribution, status, and potential management deficiencies of protected areas (PAs) harboring lions. Our study synthesized available expert opinion and field data to close this knowledge gap, and formulate recommendations for the conservation of West African lions. We undertook lion surveys in 13 large (>500 km2) PAs and compiled evidence of lion presence/absence for a further eight PAs. All PAs were situated within Lion Conservation Units, geographical units designated as priority lion areas by wildlife experts at a regional lion conservation workshop in 2005. Lions were confirmed in only 4 PAs, and our results suggest that only 406 (273–605) lions remain in West Africa, representing <250 mature individuals. Confirmed lion range is estimated at 49,000 km2, or 1.1% of historical range in West Africa. PAs retaining lions were larger than PAs without lions and had significantly higher management budgets. We encourage revision of lion taxonomy, to recognize the genetic distinctiveness of West African lions and highlight their potentially unique conservation value. Further, we call for listing of the lion as critically endangered in West Africa, under criterion C2a(ii) for populations with <250 mature individuals. Finally, considering the relative poverty of lion range states in West Africa, we call for urgent mobilization of investment from the international community to assist range

  18. The lion in West Africa is critically endangered.

    PubMed

    Henschel, Philipp; Coad, Lauren; Burton, Cole; Chataigner, Beatrice; Dunn, Andrew; MacDonald, David; Saidu, Yohanna; Hunter, Luke T B

    2014-01-01

    The African lion has declined to <35,000 individuals occupying 25% of its historic range. The situation is most critical for the geographically isolated populations in West Africa, where the species is considered regionally endangered. Elevating their conservation significance, recent molecular studies establish the genetic distinctiveness of West and Central African lions from other extant African populations. Interventions to save West African lions are urgently required. However formulating effective conservation strategies has been hampered by a lack of data on the species' current distribution, status, and potential management deficiencies of protected areas (PAs) harboring lions. Our study synthesized available expert opinion and field data to close this knowledge gap, and formulate recommendations for the conservation of West African lions. We undertook lion surveys in 13 large (>500 km²) PAs and compiled evidence of lion presence/absence for a further eight PAs. All PAs were situated within Lion Conservation Units, geographical units designated as priority lion areas by wildlife experts at a regional lion conservation workshop in 2005. Lions were confirmed in only 4 PAs, and our results suggest that only 406 (273-605) lions remain in West Africa, representing <250 mature individuals. Confirmed lion range is estimated at 49,000 km², or 1.1% of historical range in West Africa. PAs retaining lions were larger than PAs without lions and had significantly higher management budgets. We encourage revision of lion taxonomy, to recognize the genetic distinctiveness of West African lions and highlight their potentially unique conservation value. Further, we call for listing of the lion as critically endangered in West Africa, under criterion C2a(ii) for populations with <250 mature individuals. Finally, considering the relative poverty of lion range states in West Africa, we call for urgent mobilization of investment from the international community to assist range

  19. Transcending Communication Barriers with West Africa.

    ERIC Educational Resources Information Center

    Ampadu, Lena

    Americans doing business with West Africans are limited in their ability to communicate successfully in that part of the world because of language, stereotyping, and ethnocentrism. Americans must become accustomed to British patterns of speech and writing. Stereotypes of Africa, its people, and its cultures perpetuated by the media keep Americans…

  20. African Aesthetics

    ERIC Educational Resources Information Center

    Abiodun, Rowland

    2001-01-01

    No single traditional discipline can adequately supply answers to the many unresolved questions in African art history. Because of the aesthetic, cultural, historical, and, not infrequently, political biases, already built into the conception and development of Western art history, the discipline of art history as defined and practiced in the West…

  1. "African Connection."

    ERIC Educational Resources Information Center

    Adelman, Cathy; And Others

    This interdisciplinary unit provides students in grades kindergarten through seventh grade an opportunity to understand diversity through a study of Africa as a diverse continent. The project is designed to provide all elementary students with cultural enrichment by exposing them to African music, art, storytelling, and movement. This project can…

  2. African oil plays

    SciTech Connect

    Clifford, A.J. )

    1989-09-01

    The vast continent of Africa hosts over eight sedimentary basins, covering approximately half its total area. Of these basins, only 82% have entered a mature exploration phase, 9% have had little or no exploration at all. Since oil was first discovered in Africa during the mid-1950s, old play concepts continue to bear fruit, for example in Egypt and Nigeria, while new play concepts promise to become more important, such as in Algeria, Angola, Chad, Egypt, Gabon, and Sudan. The most exciting developments of recent years in African oil exploration are: (1) the Gamba/Dentale play, onshore Gabon; (2) the Pinda play, offshore Angola; (3) the Lucula/Toca play, offshore Cabinda; (4) the Metlaoui play, offshore Libya/Tunisia; (5) the mid-Cretaceous sand play, Chad/Sudan; and (6) the TAG-I/F6 play, onshore Algeria. Examples of these plays are illustrated along with some of the more traditional oil plays. Where are the future oil plays likely to develop No doubt, the Saharan basins of Algeria and Libya will feature strongly, also the presalt of Equatorial West Africa, the Central African Rift System and, more speculatively, offshore Ethiopia and Namibia, and onshore Madagascar, Mozambique, and Tanzania.

  3. Évidences paléomagnétiques et paléontologiques en faveur d'une position antipodale du craton Ouest-Africain et de la Chine du Nord : conséquences paléogéographiquesPalaeomagnetic and palaeontologic evidence for an antipodal position of the West African Craton and of northern China in the Rodinia puzzle: palaeogeographic consequences

    NASA Astrophysics Data System (ADS)

    Lefort, Jean-Pierre; Aı̈fa, Tahar; Bourrouilh, Robert

    2004-02-01

    Reappraisal of the palaeomagnetic data previously published about the West African Craton and their comparison with the most recent information obtained on doleritic dykes and stromatolite-bearing formations allow us to propose, after a critical examination of the old geochronological data, a new path for the West African Craton between 2200 and 700 Ma. This path has been compared with that of eastern China (which can be simply divided into a northern and a southern China block) between 1400 and 700 Ma. We can observe that these two blocks show a common path before their accretion to the Rodinia super-continent. These two blocks, which were located close the equator and at the outboard of Rodinia at about 1000 Ma, were also characterized by identical stromatolitic assemblages. This result shows that West Africa and Eastern China represented the antipodal continental margins of Rodinia. One can also deduce from our data that the accretion of Rodinia mainly resulted from north-south-oriented displacements. To cite this article: J.-P. Lefort et al., C. R. Geoscience 336 (2004).

  4. Horizons West.

    ERIC Educational Resources Information Center

    Kitses, Jim

    The western is the most popular and enduring of Hollywood forms. It is one embodiment of a traditional theme in American culture: the West as both Garden of natural dignity and innocence and also as treacherous Desert resisting the gradual sweep of agrarian progress and community values. Westerns have in common: a) history, America's past; b)…

  5. Obesity and African Americans

    MedlinePlus

    ... Data > Minority Population Profiles > Black/African American > Obesity Obesity and African Americans African American women have the ... ss6304.pdf [PDF | 3.38MB] HEALTH IMPACT OF OBESITY More than 80 percent of people with type ...

  6. Infection of African buffalo (Syncerus caffer) by oryx bacillus, a rare member of the antelope clade of the Mycobacterium tuberculosis complex.

    PubMed

    Gey van Pittius, Nicolaas C; Perrett, Keith D; Michel, Anita L; Keet, Dewald F; Hlokwe, Tiny; Streicher, Elizabeth M; Warren, Robin M; van Helden, Paul D

    2012-10-01

    Mycobacterium tuberculosis complex species cause tuberculosis disease in animals and humans. Although they share 99.9% similarity at the nucleotide level, several host-adapted ecotypes of the tubercule bacilli have been identified. In the wildlife setting, probably the most well-known member of this complex is Mycobacterium bovis, the causative agent of bovine tuberculosis. The recently described oryx bacillus is an extremely rare slow-growing member of the antelope clade of the M. tuberculosis complex and is closely related to the dassie bacillus, Mycobacterium africanum and Mycobacterium microti. The antelope clade is a group of strains apparently host adapted to antelopes, as most described infections were associated with deer and antelope, most specifically the Arabian oryx (Oryx leucoryx). In this study, oryx bacillus was isolated from a free-ranging adult female African buffalo (Syncerus caffer), in good physical condition, which tested strongly positive on three consecutive comparative intradermal tuberculin tests. Upon necropsy, a single pulmonary granuloma and an active retropharyngeal lymph node was found. Comprehensive molecular genetic assays were performed, which confirmed that the causative microorganism was not M. bovis but oryx bacillus. Oryx bacillus has never been reported in Southern Africa and has never been found to infect African buffalo. The identification of this microorganism in buffalo is an important observation in view of the large and ever-increasing epidemic of the closely related M. tuberculosis complex species M. bovis in some African buffalo populations in South Africa. PMID:23060486

  7. Micropaleontology and biostratigraphy of the coastal basins of West Africa

    SciTech Connect

    Kogbe, C.A.; Mehes, K.

    1986-01-01

    This book is intended to meet the need for a single volume on descriptive micropaleontology of West African microfauna assemblage which is different from that of the Boreal, Mediterranean, Pacific and Atlantic regions. The contents include: Preface. Introduction. Systematics: West African foraminifera species: Systematic classification and description. Glossary for the foraminifera. Selected references for the foraminifera. The ostracoda: Systematic classification and description. Glossary for the ostracoda. Selected references for the ostracoda. Stratigraphic Sequences of the West African Coastal Basins: General review. Angola-Cuanza basin. Congo. Gabon. Cameroun-Douala basin. Nigeria. Togo-Benin basin. Ghana. Ivory Coast. Senegal. Appendix: Brief classification of foraminifera. Paleo-ecology of the foraminifera. Testing of samples. Collection of samples. Preparation of samples. Preparation of thin sections. Storage of microfossils. Methods of examination. Index.

  8. The Great Migration and African-American Genomic Diversity

    PubMed Central

    Barakatt, Maxime; Gignoux, Christopher R.; Errington, Jacob; Blot, William J.; Bustamante, Carlos D.; Kenny, Eimear E.; Williams, Scott M.; Aldrich, Melinda C.; Gravel, Simon

    2016-01-01

    We present a comprehensive assessment of genomic diversity in the African-American population by studying three genotyped cohorts comprising 3,726 African-Americans from across the United States that provide a representative description of the population across all US states and socioeconomic status. An estimated 82.1% of ancestors to African-Americans lived in Africa prior to the advent of transatlantic travel, 16.7% in Europe, and 1.2% in the Americas, with increased African ancestry in the southern United States compared to the North and West. Combining demographic models of ancestry and those of relatedness suggests that admixture occurred predominantly in the South prior to the Civil War and that ancestry-biased migration is responsible for regional differences in ancestry. We find that recent migrations also caused a strong increase in genetic relatedness among geographically distant African-Americans. Long-range relatedness among African-Americans and between African-Americans and European-Americans thus track north- and west-bound migration routes followed during the Great Migration of the twentieth century. By contrast, short-range relatedness patterns suggest comparable mobility of ∼15–16km per generation for African-Americans and European-Americans, as estimated using a novel analytical model of isolation-by-distance. PMID:27232753

  9. The Great Migration and African-American Genomic Diversity.

    PubMed

    Baharian, Soheil; Barakatt, Maxime; Gignoux, Christopher R; Shringarpure, Suyash; Errington, Jacob; Blot, William J; Bustamante, Carlos D; Kenny, Eimear E; Williams, Scott M; Aldrich, Melinda C; Gravel, Simon

    2016-05-01

    We present a comprehensive assessment of genomic diversity in the African-American population by studying three genotyped cohorts comprising 3,726 African-Americans from across the United States that provide a representative description of the population across all US states and socioeconomic status. An estimated 82.1% of ancestors to African-Americans lived in Africa prior to the advent of transatlantic travel, 16.7% in Europe, and 1.2% in the Americas, with increased African ancestry in the southern United States compared to the North and West. Combining demographic models of ancestry and those of relatedness suggests that admixture occurred predominantly in the South prior to the Civil War and that ancestry-biased migration is responsible for regional differences in ancestry. We find that recent migrations also caused a strong increase in genetic relatedness among geographically distant African-Americans. Long-range relatedness among African-Americans and between African-Americans and European-Americans thus track north- and west-bound migration routes followed during the Great Migration of the twentieth century. By contrast, short-range relatedness patterns suggest comparable mobility of ∼15-16km per generation for African-Americans and European-Americans, as estimated using a novel analytical model of isolation-by-distance. PMID:27232753

  10. The Great Migration and African-American Genomic Diversity.

    PubMed

    Baharian, Soheil; Barakatt, Maxime; Gignoux, Christopher R; Shringarpure, Suyash; Errington, Jacob; Blot, William J; Bustamante, Carlos D; Kenny, Eimear E; Williams, Scott M; Aldrich, Melinda C; Gravel, Simon

    2016-05-01

    We present a comprehensive assessment of genomic diversity in the African-American population by studying three genotyped cohorts comprising 3,726 African-Americans from across the United States that provide a representative description of the population across all US states and socioeconomic status. An estimated 82.1% of ancestors to African-Americans lived in Africa prior to the advent of transatlantic travel, 16.7% in Europe, and 1.2% in the Americas, with increased African ancestry in the southern United States compared to the North and West. Combining demographic models of ancestry and those of relatedness suggests that admixture occurred predominantly in the South prior to the Civil War and that ancestry-biased migration is responsible for regional differences in ancestry. We find that recent migrations also caused a strong increase in genetic relatedness among geographically distant African-Americans. Long-range relatedness among African-Americans and between African-Americans and European-Americans thus track north- and west-bound migration routes followed during the Great Migration of the twentieth century. By contrast, short-range relatedness patterns suggest comparable mobility of ∼15-16km per generation for African-Americans and European-Americans, as estimated using a novel analytical model of isolation-by-distance.

  11. West Africa

    NASA Technical Reports Server (NTRS)

    2002-01-01

    With its vast expanses of sand, framed by mountain ranges and exposed rock, northwestern Africa makes a pretty picture when viewed from above. This image was acquired by the Moderate-resolution Imaging Spectroradiometer (MODIS), flying aboard NASA's Terra spacecraft. The Canary Islands can be seen on the left side of the image just off Africa's Atlantic shore. The light brown expanse running through the northern two thirds of the image is the Sahara Desert. The desert runs up against the dark brown Haut Atlas mountain range of Morocco in the northwest, the Atlantic Ocean to the west and the semi-arid (light brown pixels) Sahelian region in the South. The Sahara, however, isn't staying put. Since the 1960s, the desert has been expanding into the Sahelian region at a rate of up to 6 kilometers per year. In the 1980s this desert expansion, combined with over cultivation of the Sahel, caused a major famine across west Africa. Over the summer months, strong winds pick up sands from the Sahara and blow them across the Atlantic as far west as North America, causing air pollution in Miami and damaging coral reefs in the Bahamas and the Florida Keys. The white outlines on the map represent country borders. Starting at the top-most portion of the map and working clockwise, the countries shown are Morocco, Western Sahara, Mauritania, Senegal, Mali, Burkina Fasso, Nigeria, Mali (again), and Algeria. Image by Reto Stockli, Robert Simmon, and Brian Montgomery, NASA Earth Observatory, based on data from MODIS

  12. Range and Frequency of Africanized Honey Bees in California (USA)

    PubMed Central

    Kono, Yoshiaki; Kohn, Joshua R.

    2015-01-01

    Africanized honey bees entered California in 1994 but few accounts of their northward expansion or their frequency relative to European honey bees have been published. We used mitochondrial markers and morphometric analyses to determine the prevalence of Africanized honeybees in San Diego County and their current northward progress in California west of the Sierra Nevada crest. The northernmost African mitotypes detected were approximately 40 km south of Sacramento in California’s central valley. In San Diego County, 65% of foraging honey bee workers carry African mitochondria and the estimated percentage of Africanized workers using morphological measurements is similar (61%). There was no correlation between mitotype and morphology in San Diego County suggesting Africanized bees result from bidirectional hybridization. Seventy percent of feral hives, but only 13% of managed hives, sampled in San Diego County carried the African mitotype indicating that a large fraction of foraging workers in both urban and rural San Diego County are feral. We also found a single nucleotide polymorphism at the DNA barcode locus COI that distinguishes European and African mitotypes. The utility of this marker was confirmed using 401 georeferenced honey bee sequences from the worldwide Barcode of Life Database. Future censuses can determine whether the current range of the Africanized form is stable, patterns of introgression at nuclear loci, and the environmental factors that may limit the northern range of the Africanized honey bee. PMID:26361047

  13. Range and Frequency of Africanized Honey Bees in California (USA).

    PubMed

    Kono, Yoshiaki; Kohn, Joshua R

    2015-01-01

    Africanized honey bees entered California in 1994 but few accounts of their northward expansion or their frequency relative to European honey bees have been published. We used mitochondrial markers and morphometric analyses to determine the prevalence of Africanized honeybees in San Diego County and their current northward progress in California west of the Sierra Nevada crest. The northernmost African mitotypes detected were approximately 40 km south of Sacramento in California's central valley. In San Diego County, 65% of foraging honey bee workers carry African mitochondria and the estimated percentage of Africanized workers using morphological measurements is similar (61%). There was no correlation between mitotype and morphology in San Diego County suggesting Africanized bees result from bidirectional hybridization. Seventy percent of feral hives, but only 13% of managed hives, sampled in San Diego County carried the African mitotype indicating that a large fraction of foraging workers in both urban and rural San Diego County are feral. We also found a single nucleotide polymorphism at the DNA barcode locus COI that distinguishes European and African mitotypes. The utility of this marker was confirmed using 401 georeferenced honey bee sequences from the worldwide Barcode of Life Database. Future censuses can determine whether the current range of the Africanized form is stable, patterns of introgression at nuclear loci, and the environmental factors that may limit the northern range of the Africanized honey bee.

  14. Range and Frequency of Africanized Honey Bees in California (USA).

    PubMed

    Kono, Yoshiaki; Kohn, Joshua R

    2015-01-01

    Africanized honey bees entered California in 1994 but few accounts of their northward expansion or their frequency relative to European honey bees have been published. We used mitochondrial markers and morphometric analyses to determine the prevalence of Africanized honeybees in San Diego County and their current northward progress in California west of the Sierra Nevada crest. The northernmost African mitotypes detected were approximately 40 km south of Sacramento in California's central valley. In San Diego County, 65% of foraging honey bee workers carry African mitochondria and the estimated percentage of Africanized workers using morphological measurements is similar (61%). There was no correlation between mitotype and morphology in San Diego County suggesting Africanized bees result from bidirectional hybridization. Seventy percent of feral hives, but only 13% of managed hives, sampled in San Diego County carried the African mitotype indicating that a large fraction of foraging workers in both urban and rural San Diego County are feral. We also found a single nucleotide polymorphism at the DNA barcode locus COI that distinguishes European and African mitotypes. The utility of this marker was confirmed using 401 georeferenced honey bee sequences from the worldwide Barcode of Life Database. Future censuses can determine whether the current range of the Africanized form is stable, patterns of introgression at nuclear loci, and the environmental factors that may limit the northern range of the Africanized honey bee. PMID:26361047

  15. Africans in America.

    ERIC Educational Resources Information Center

    Hart, Ayanna; Spangler, Earl

    This book introduces African-American history and culture to children. The first Africans in America came from many different regions and cultures, but became united in this country by being black, African, and slaves. Once in America, Africans began a long struggle for freedom which still continues. Slavery, the Civil War, emancipation, and the…

  16. Therapy with African Families.

    ERIC Educational Resources Information Center

    Nwadiora, Emeka

    1996-01-01

    Informs helping professionals about the unique history and challenges of African families to guide them toward providing ethnically sensitive psychological services to African immigrant families in need. African families undergo great stress when faced with the alienation of being Black and African in a Euro-American culture. (SLD)

  17. African Outreach Workshop 1974.

    ERIC Educational Resources Information Center

    Schmidt, Nancy J.

    This report discusses the 1974 African Outreach Workshop planned and coordinated by the African Studies Program at the University of Illinois at Urbana-Champaign. Its major aim was to assist teachers in developing curriculum units on African using materials available in their local community. A second aim was for the African Studies Program to…

  18. African easterly wave energetics on intraseasonal timescales

    NASA Astrophysics Data System (ADS)

    Alaka, Ghassan J., Jr.

    African easterly waves (AEWs) are synoptic-scale eddies that dominate North African weather in boreal summer. AEWs propagate westward with a maximum amplitude near 700 hPa and a period of 2.5-6-days. AEWs and associated perturbation kinetic energy (PKE) exhibit significant intraseasonal variability in tropical North Africa during boreal summer, which directly impacts local agriculture and tropical cyclogenesis. This study performs a comprehensive analysis of the 30-90-day variability of AEWs and associated energetics using both reanalysis data and model output. Specifically, the PKE and perturbation available potential energy (PAPE) budgets are used to understand the factors that contribute to PKE maxima in West Africa and the extent to which these surges of AEW activity are modulated by the Madden-Julian oscillation (MJO). The role of the MJO in the intraseasonal variability of AEWs is assessed by comparing PKE sources as a function of an MJO index and a local 30-90-day West African PKE index. Since East Africa is an initiation zone for AEW activity and is modulated by the MJO, the relationship between this region and West Africa is a primary focus in this study. The intraseasonal variability of AEW energetics is first investigated in reanalysis products. While reanalysis data depicts a similar evolution of 30-90-day PKE anomalies in both the MJO and a local PKE index, the MJO index describes only a small (yet still significant) fraction of the local 30-90-day variance. In boreal summers with more significant MJO days, the correlation between the two indices is higher. Baroclinic energy conversions are important for the initiation of 30-90-day West African PKE events east of Lake Chad. In West Africa, both barotropic and baroclinic energy conversions maintain positive PKE anomalies before they propagate into the Atlantic. The primary role of diabatic heating is to destroy PAPE in a negative feedback to baroclinic energy conversions in West Africa. More frequent

  19. The Making of the African mtDNA Landscape

    PubMed Central

    Salas, Antonio; Richards, Martin; De la Fe, Tomás; Lareu, María-Victoria; Sobrino, Beatriz; Sánchez-Diz, Paula; Macaulay, Vincent; Carracedo, Ángel

    2002-01-01

    Africa presents the most complex genetic picture of any continent, with a time depth for mitochondrial DNA (mtDNA) lineages >100,000 years. The most recent widespread demographic shift within the continent was most probably the Bantu dispersals, which archaeological and linguistic evidence suggest originated in West Africa 3,000–4,000 years ago, spreading both east and south. Here, we have carried out a thorough phylogeographic analysis of mtDNA variation in a total of 2,847 samples from throughout the continent, including 307 new sequences from southeast African Bantu speakers. The results suggest that the southeast Bantu speakers have a composite origin on the maternal line of descent, with ∼44% of lineages deriving from West Africa, ∼21% from either West or Central Africa, ∼30% from East Africa, and ∼5% from southern African Khoisan-speaking groups. The ages of the major founder types of both West and East African origin are consistent with the likely timing of Bantu dispersals, with those from the west somewhat predating those from the east. Despite this composite picture, the southeastern African Bantu groups are indistinguishable from each other with respect to their mtDNA, suggesting that they either had a common origin at the point of entry into southeastern Africa or have undergone very extensive gene flow since. PMID:12395296

  20. The making of the African mtDNA landscape.

    PubMed

    Salas, Antonio; Richards, Martin; De la Fe, Tomás; Lareu, María-Victoria; Sobrino, Beatriz; Sánchez-Diz, Paula; Macaulay, Vincent; Carracedo, Angel

    2002-11-01

    Africa presents the most complex genetic picture of any continent, with a time depth for mitochondrial DNA (mtDNA) lineages >100,000 years. The most recent widespread demographic shift within the continent was most probably the Bantu dispersals, which archaeological and linguistic evidence suggest originated in West Africa 3,000-4,000 years ago, spreading both east and south. Here, we have carried out a thorough phylogeographic analysis of mtDNA variation in a total of 2,847 samples from throughout the continent, including 307 new sequences from southeast African Bantu speakers. The results suggest that the southeast Bantu speakers have a composite origin on the maternal line of descent, with approximately 44% of lineages deriving from West Africa, approximately 21% from either West or Central Africa, approximately 30% from East Africa, and approximately 5% from southern African Khoisan-speaking groups. The ages of the major founder types of both West and East African origin are consistent with the likely timing of Bantu dispersals, with those from the west somewhat predating those from the east. Despite this composite picture, the southeastern African Bantu groups are indistinguishable from each other with respect to their mtDNA, suggesting that they either had a common origin at the point of entry into southeastern Africa or have undergone very extensive gene flow since.

  1. Factors influencing prostate cancer healthcare practices in Barbados, West Indies.

    PubMed

    Ng, Patricia; Schoenfeld, Elinor R; Hennis, Anselm; Wu, Suh-Yuh; Leske, M Cristina; Nemesure, Barbara

    2013-06-01

    Although some investigations have assessed the barriers to prostate cancer screening among African-