Science.gov

Sample records for age national origin

  1. Employment Discrimination: Age, Sex and National Origin.

    ERIC Educational Resources Information Center

    Carter, David G.; Lawson, Miriam

    Chapter 17 of a book on school law is an historical review of judicial decisions and legislative enactments that apply to employment. The purpose of the chapter is to analyze those cases concerned with discrimination because of sex, age, or national origin, and to discuss the decisions of the U.S. Supreme Court in these areas. Not until the…

  2. The origins of human ageing.

    PubMed Central

    Kirkwood, T B

    1997-01-01

    The origins of human ageing are to be found in the origins and evolution of senescence as a general feature in the life histories of higher animals. Ageing is an intriguing problem in evolutionary biology because a trait that limits the duration of life, including the fertile period, has a negative impact on Darwinian fitness. Current theory suggests that senescence occurs because the force of natural selection declines with age and because longevity is only acquired at some metabolic cost. In effect, organisms may trade late survival for enhanced reproductive investments in earlier life. The comparative study of ageing supports the general evolutionary theory and reveals that human senescence, while broadly similar to senescence in other mammalian species, has distinct features, such as menopause, that may derive from the interplay of biological and social evolution. PMID:9460059

  3. Fetal origin of vascular aging

    PubMed Central

    Pitale, Shailesh; Sahasrabuddhe, Anagha

    2011-01-01

    Aging is increasingly regarded as an independent risk factor for development of cardiovascular diseases such as atherosclerosis and hypertension and their complications (e.g. MI and Stroke). It is well known that vascular disease evolve over decades with progressive accumulation of cellular and extracellular materials and many inflammatory processes. Metabolic syndrome, obesity and diabetes are conventionally recognized as risk factors for development of coronary vascular disease (CVD). These conditions are known to accelerate ageing process in general and vascular ageing in particular. Adverse events during intrauterine life may programme organ growth and favour disease later in life, popularly known as, ‘Barker's Hypothesis’. The notion of fetal programming implies that during critical periods of prenatal growth, changes in the hormonal and nutritional milieu of the conceptus may alter the full expression of the fetal genome, leading to permanent effects on a range of physiological. PMID:22145131

  4. National Institute on Aging

    MedlinePlus

    ... Join Our Mailing List Email The Leader in Aging Research NIA, one of the 27 Institutes and ... broad scientific effort to understand the nature of aging and to extend the healthy, active years of ...

  5. Photocopy of original drawings (original located at the National Archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of original drawings (original located at the National Archives, San Bruno, California, Navy # 104-A-22), showing current floor plan. Department of the Navy, Bureau of Yards and Docks, "Record drawing, N.D. - Mare Island Naval Shipyard, St. Peter's Chapel, Walnut Street & Cedar Parkway, Vallejo, Solano County, CA

  6. Photocopy of original drawings (original located at the National Archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of original drawings (original located at the National Archives, San Bruno, California, Navy # 104-A-4, showing organ recess. Dept. yards & docks, U.S. Navy, Mare Island, Cal., "Plan & Sections, proposed addition, St. Peter's Chapel, December 1904 - Mare Island Naval Shipyard, St. Peter's Chapel, Walnut Street & Cedar Parkway, Vallejo, Solano County, CA

  7. Photocopy of original drawings (original located at the National Archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of original drawings (original located at the National Archives, San Bruno, California, Navy # 104-A-5). Depts. Yards & docks, U.S. Navy Mare Island, Cal., "full sized detail of fretwork panels in back of organ recess, St. Peter's Chapel, Mare Island, Cal., December 1904. - Mare Island Naval Shipyard, St. Peter's Chapel, Walnut Street & Cedar Parkway, Vallejo, Solano County, CA

  8. Photocopy of original drawings (original located at the National Archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of original drawings (original located at the National Archives, San Bruno, California, Navy # 104-A-7. "Full size sketch of 2 candelabra stands for St. Peters Chapel, Mare Island, Calif.," October 1908. - Mare Island Naval Shipyard, St. Peter's Chapel, Walnut Street & Cedar Parkway, Vallejo, Solano County, CA

  9. Photocopy of original drawings (original located at the National Archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of original drawings (original located at the National Archives, San Bruno, California, Navy # 104-A-14). Dept. of yards and docks, "Chapel amplifier support," October 1945. - Mare Island Naval Shipyard, St. Peter's Chapel, Walnut Street & Cedar Parkway, Vallejo, Solano County, CA

  10. Photocopy of original drawings (original located at the National Archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of original drawings (original located at the National Archives, San Bruno, California, Navy # 104-A-1), showing ground plan. Albert Sutton, plan for yard chapel at U.S. Navy Yard, Mare Island, Cal., November 1900. - Mare Island Naval Shipyard, St. Peter's Chapel, Walnut Street & Cedar Parkway, Vallejo, Solano County, CA

  11. Photocopy of original drawings (original located at the National Archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of original drawings (original located at the National Archives, San Bruno, California, Navy # 104-A-2), showing front elevation and section. Albert Sutton, plan for yard chapel at U.S. Navy Yard, Mare Island, Cal., November 1900. - Mare Island Naval Shipyard, St. Peter's Chapel, Walnut Street & Cedar Parkway, Vallejo, Solano County, CA

  12. Photocopy of original drawings (original located at the National Archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of original drawings (original located at the National Archives, San Bruno, California, Navy # 104-A-3, showing side and rear elevation. Albert Sutton, "plan for yard chapel at the U.S. Navy Yard, Mare Island, Cal.," November 1900. - Mare Island Naval Shipyard, St. Peter's Chapel, Walnut Street & Cedar Parkway, Vallejo, Solano County, CA

  13. Photograph of original drawing (original in possession of National Passenger ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photograph of original drawing (original in possession of National Passenger Railroad Corporation). STATION BUILDING: Foundation Plan / Alterations and Additions (dated: 7/17/14) - North Philadelphia Station, 2900 North Broad Street, on northwest corner of Broad Street & Glenwood Avenue, Philadelphia, Philadelphia County, PA

  14. Photocopy of original drawings (original located at the National Archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of original drawings (original located at the National Archives, San Bruno, California, Navy # A-21). Dept. of the Navy District Public Works Office, "additions, floor plan, elevations & details; architectural, mechanical & electrical," May 1963. - Mare Island Naval Shipyard, St. Peter's Chapel, Walnut Street & Cedar Parkway, Vallejo, Solano County, CA

  15. Photocopy of original drawings (original located at the National Archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of original drawings (original located at the National Archives, San Bruno, California, Navy # 104-A-25) William Jeffries Associates, A.I.A., "Repair to stained glass window, building 104, elevation & details," September 1952. - Mare Island Naval Shipyard, St. Peter's Chapel, Walnut Street & Cedar Parkway, Vallejo, Solano County, CA

  16. Photocopy of original drawings (original located at the National Archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of original drawings (original located at the National Archives, San Bruno, California, Navy # 104-A-9). (Signed) Ralph Whitman, public works officer, "Yard chapel addition to house organ, etc., plans, elevations, details," September 1929. - Mare Island Naval Shipyard, St. Peter's Chapel, Walnut Street & Cedar Parkway, Vallejo, Solano County, CA

  17. Photocopy of original drawings (original located at the National Archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of original drawings (original located at the National Archives, San Bruno, California, Navy # 104-A-13). (Signed) Ralph Whitman, public works officer, "Yard chapel organ addition mill details, exterior window," September 1929. - Mare Island Naval Shipyard, St. Peter's Chapel, Walnut Street & Cedar Parkway, Vallejo, Solano County, CA

  18. 76 FR 65203 - National Institute on Aging

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-20

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging ACTION: Notice of Closed... of Committee: National Institute on Aging Special Emphasis Panel; Mechanisms of Osteoporosis II. Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  19. 29 CFR 1606.1 - Definition of national origin discrimination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Definition of national origin discrimination. 1606.1... GUIDELINES ON DISCRIMINATION BECAUSE OF NATIONAL ORIGIN § 1606.1 Definition of national origin discrimination. The Commission defines national origin discrimination broadly as including, but not limited to,...

  20. 76 FR 21386 - National Institute on Aging

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-15

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Organelle Lifespan Mechanism II. Date: June... Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892...

  1. Aging Education: A National Imperative

    ERIC Educational Resources Information Center

    McGuire, Sandra L.; Klein, Diane A.; Couper, Donna

    2005-01-01

    Americans are living longer than ever before. However, many are not prepared for the long life ahead of them. Although lifespan-aging education has been endorsed since the first White House Conference on Aging in 1961, little is happening with aging education in our homes, schools and communities. Americans often reach old age with little or no…

  2. NATIONAL ARCHIVE OF COMPUTERIZED DATA ON AGING

    EPA Science Inventory

    The National Archive of Computerized Data on Aging (NACDA), located within ICPSR, is funded by the National Institute on Aging. NACDA's mission is to advance research on aging by helping researchers to profit from the under-exploited potential of a broad range of datasets. NACDA ...

  3. National Association of Area Agencies on Aging

    MedlinePlus

    National Association of Area Agencies on Aging Search Member Login Forgot Password? Menu ABOUT n4a Mission, Vision & Work AAAs & Title VI Aging Programs Membership Board of Directors Staff Contact ...

  4. 27 CFR 5.52 - Certificates of age and origin.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... origin. 5.52 Section 5.52 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU... From Customs Custody of Bottled Imported Distilled Spirits § 5.52 Certificates of age and origin. (a... certificate of origin issued by a duly authorized official of the British, Irish, or Canadian...

  5. National Origin and Behavioural Problems of Toddlers: The Role of Family Risk Factors and Maternal Immigration Characteristics

    ERIC Educational Resources Information Center

    Jansen, Pauline W.; Raat, Hein; Mackenbach, Johan P.; Jaddoe, Vincent W. V.; Hofman, Albert; van Oort, Floor V.; Verhulst, Frank C.; Tiemeier, Henning

    2010-01-01

    In many societies the prevalence of behavioural problems in school-aged children varies by national origin. We examined the association between national origin and behavioural problems in 1 1/2-year-old children. Data on maternal national origin and the Child Behavior Checklist for toddlers (n = 4943) from a population-based cohort in the…

  6. Conforming Amendments to the Regulations Governing Nondiscrimination on the Basis of Race, Color, National, Origin, Disability, Sex, and Age under the Civil Rights Restoration Act of 1987; Final Rule. Federal Register, Part IV: Department of Education, 34 CFR Parts 100, 104, 106, and 110.

    ERIC Educational Resources Information Center

    Federal Register, 2000

    2000-01-01

    The Secretary amends the regulations governing nondiscrimination on the basis of race, color, national origin, sex, handicap, and age to conform with statutory amendments made by the Civil Rights Restoration Act of 1987 (CRRA). These amendments add a definition of "program or activity" or "program" that adopts the statutory definition of "program…

  7. Age of EET79001B and Implications for Shergottite Origins

    NASA Technical Reports Server (NTRS)

    Nyquist, L. E.; Reese, Y.; Wiesmann, H.; Shih, C.-Y.

    2001-01-01

    A precise Rb-Sr age of 174+/-3 Ma was determined for EET79001B. A Sm-Nd age of 169+/-23 Ma also was determined, but the Nd isotopic systematics are disturbed. This disturbance is attributed to incomplete isotopic equilibration during petrogenesis. Additional information is contained in the original extended abstract.

  8. 75 FR 56551 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-16

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... conducted by the National Institute on Aging, including consideration of personnel qualifications and... individual investigators. Place: National Institute on Aging, Biomedical Research Center, 251...

  9. Equality of Educational Opportunity for National Origin Minority Students.

    ERIC Educational Resources Information Center

    Ochoa, Alberto M.

    The legal bases of federal and state requirements for addressing the linguistic and academic needs of national origin minority students are reviewed. A national origin minority student is defined as one whose home language is other than English and who is not performing up to district standards of proficiency. The legal milestone leading to…

  10. 18 CFR 1300.105 - National origin harassment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... harassment. 1300.105 Section 1300.105 Conservation of Power and Water Resources TENNESSEE VALLEY AUTHORITY STANDARDS OF CONDUCT FOR EMPLOYEES OF TENNESSEE VALLEY AUTHORITY § 1300.105 National origin harassment. It... national origin harassment. Accordingly, all employees must avoid any action or conduct which could...

  11. 18 CFR 1300.105 - National origin harassment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false National origin harassment. 1300.105 Section 1300.105 Conservation of Power and Water Resources TENNESSEE VALLEY AUTHORITY STANDARDS OF CONDUCT FOR EMPLOYEES OF TENNESSEE VALLEY AUTHORITY § 1300.105 National origin harassment....

  12. 18 CFR 1300.105 - National origin harassment.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 2 2012-04-01 2012-04-01 false National origin harassment. 1300.105 Section 1300.105 Conservation of Power and Water Resources TENNESSEE VALLEY AUTHORITY STANDARDS OF CONDUCT FOR EMPLOYEES OF TENNESSEE VALLEY AUTHORITY § 1300.105 National origin harassment....

  13. 18 CFR 1300.105 - National origin harassment.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 2 2014-04-01 2014-04-01 false National origin harassment. 1300.105 Section 1300.105 Conservation of Power and Water Resources TENNESSEE VALLEY AUTHORITY STANDARDS OF CONDUCT FOR EMPLOYEES OF TENNESSEE VALLEY AUTHORITY § 1300.105 National origin harassment....

  14. [Thermodynamics of the origin of life, evolution and aging].

    PubMed

    Gladyshev, G P

    2014-01-01

    Briefly discusses the history of the search of thermodynamic approach to explain the origin of life, evolution and aging of living beings. The origin of life is the result of requirement by the quasi-equilibrium hierarchical thermodynamics, in particular, the supramolecular thermodynamics. The evolution and aging of living beings is accompanied with changes of chemical and supramolecular compositions of living bodies, as well as with changes in the composition and structure of all hierarchies of the living world. The thermodynamic principle of substance stability predicts the existence of a single genetic code in our universe. The thermodynamic theory optimizes physiology and medicine and recommends antiaging diets and medicines. Hierarchical thermodynamics forms the design diversity of culture and art. The thermodynamic theory of origin of life, evolution and aging is the development of Clausius-Gibbs thermodynamics. Hierarchical thermodynamics is the mirror of Darwin-Wallace's-theory. PMID:25306651

  15. Age and Origin of the Crustal Dichotomy in Eastern Mars

    NASA Technical Reports Server (NTRS)

    Frey, H. V.

    2002-01-01

    The crustal dichotomy in eastern Mars is largely due to the very large impact which produced the Utopia Basin. Buried impact basins on the Utopia Basin constrain the Utopia impact (and therefore the dichotomy) to be very Early Noachian in age. Additional information is contained in the original extended abstract.

  16. 76 FR 57062 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... conducted by the National Institute on Aging, including consideration of personnel qualifications and... qualifications and performance, and competence of individual investigators. Place: National Institute on...

  17. 78 FR 46995 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-02

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... conducted by the NATIONAL INSTITUTE ON AGING, including consideration of personnel qualifications and... qualifications and performance, and competence of individual investigators. Place: National Institute on...

  18. 14. Photocopy of drawing (Original in collection of National Archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photocopy of drawing (Original in collection of National Archives, # 121-BA-9373D) Delineator unknown, date unknown FOURTH FLOOR PLAN - U.S. Post Office Department, 1100 Pennsylvania Avenue Northwest, Washington, District of Columbia, DC

  19. 10. Photocopy of negative (original in possession of Chiricahua National ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Photocopy of negative (original in possession of Chiricahua National Monument), photographer unknown, c.1910 JA HU STAFFORD AND YOUNGEST DAUGHTER IN FRONT OF WEST SIDE OF CABIN - Faraway Ranch, Stafford-Riggs Cabin, Willcox, Cochise County, AZ

  20. 8. Photocopy of drawing (Original in possession of National Archives ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Photocopy of drawing (Original in possession of National Archives and Record Service, Record Group 92) Delineator unknown, Date unknown BASEMENT FLOOR PLAN - Omaha Quartermaster Depot Historic District, Twenty-second & Woolworth Streets, Omaha, Douglas County, NE

  1. 9. Photocopy of drawing (Original in possession of National Archives ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Photocopy of drawing (Original in possession of National Archives and Record Service, Record Group 92) Delineator unknown, Date unknown FIRST FLOOR PLAN - Omaha Quartermaster Depot Historic District, Twenty-second & Woolworth Streets, Omaha, Douglas County, NE

  2. 10. Photocopy of drawing (Original in possession of National Archives ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Photocopy of drawing (Original in possession of National Archives and Record Service, Record Group 92) Delineator unknown, Date unknown SECOND FLOOR PLAN - Omaha Quartermaster Depot Historic District, Twenty-second & Woolworth Streets, Omaha, Douglas County, NE

  3. 24. Photocopy of photograph (Location of original, National Register files, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    24. Photocopy of photograph (Location of original, National Register files, Washington, D.C.; original taken by Plaza Development, Inc. 1980) Photocopy taken by CESI, Washington, D.C. 1984. Exterior, north elevation - Odd Fellows Building, 1019 Southwest Tenth Street, Portland, Multnomah County, OR

  4. 25. Photocopy of photograph (Location of original, National Register files, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    25. Photocopy of photograph (Location of original, National Register files, Washington, D.C.; original taken by Plaza Development, Inc., 1980) Photocopy taken by CESI, Washington, D.C., 1984. Exterior, south and east elevation - Odd Fellows Building, 1019 Southwest Tenth Street, Portland, Multnomah County, OR

  5. 76 FR 30374 - National Institute on Aging; Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Meetings Notice of Closed... of Committee: National Institute on Aging Special Emphasis Panel; Member Conflict Sep. Date: June 2..., PhD, Chief, Scientific Review Branch, National Institute on Aging, National Institutes of...

  6. Tracing the Origins of Success: Implications for Successful Aging

    PubMed Central

    Peterson, Nora M.; Martin, Peter

    2015-01-01

    Purpose of the Study: This paper addresses the debate about the use of the term “successful aging” from a humanistic, rather than behavioral, perspective. It attempts to uncover what success, a term frequently associated with aging, is: how can it be defined and when did it first come into use? In this paper, we draw from a number of humanistic perspectives, including the historical and linguistic, in order to explore the evolution of the term “success.” We believe that words and concepts have deep implications for how concepts (such as aging) are culturally and historically perceived. Design and Methods: We take a comparative approach, turning to the etymological roots of this term in British, French, and German literature. According to the earliest entries of the term in the Oxford English Dictionary, events can have good or bad success. Another definition marks success as outcome oriented. Results: Often used in the context of war, religion, and medicine, the neutral, but often negative, use of “success” in literature of the Renaissance demonstrates the tensions that surround the word, and suggests that success is something to be approached carefully. Implications: Ignoring the ambiguous origins of success erases the fact that aging in earlier centuries echoes much of the same ambivalence with which many people discuss it today. Attending to the origins of success can help gerontologists understand the humanistic tradition behind their inquiry into what successful aging means today. PMID:24997595

  7. Seat belt use among Hispanic ethnic subgroups of national origin

    PubMed Central

    Briggs, N C; Schlundt, D G; Levine, R S; Goldzweig, I A; Stinson, N; Warren, R C

    2006-01-01

    Objective Findings from over a dozen studies of Hispanic/white disparities in seat belt use have been inconsistent, variably revealing that seat belt use prevalence among Hispanics is higher, lower, or comparable to use among non‐Hispanics. In contrast to previous studies, this study investigates disparities in seat belt use by Hispanic subgroups of national origin. Methods Data from the US Fatality Analysis Reporting System were used to compare seat belt use among 60 758 non‐Hispanic whites and 6879 Hispanics (Mexican American (MA), n = 5175; Central American/South American (CASA), n = 876; Puerto Rican (PR), n = 412; Cuban (CU), n = 416) killed in crashes from 1999–2003. Logistic regression was used to adjust for age, gender, seat belt law, seat position, urban/rural region, and income. Results Overall adjusted odds ratios for seat belt use among Hispanic subgroups, relative to non‐Hispanic whites, were 1.04 (95% confidence interval (CI) 0.85 to 1.28) for CUs, 1.17 (95% CI 0.95 to 1.44) for PRs, 1.33 (95% CI 1.25 to 1.42) for MAs, and 1.66 (95% CI 1.44 to 1.91) for CASAs. Relative to their non‐Hispanic white counterparts, odds ratios among MA and CASA Hispanics were highest for men, younger age groups, drivers, primary law states, rural areas, and lower income quartiles. Conclusion Among all Hispanic subgroups, seat belt use was at least as prevalent as among non‐Hispanic whites. In the CASA and MA subgroups, which have the most rapidly growing subpopulations of immigrants, seat belt use was significantly more common than among whites. PMID:17170195

  8. Down Syndrome: Parental Origin, Recombination, and Maternal Age

    PubMed Central

    Vraneković, Jadranka; Božović, Ivana Babić; Grubić, Zorana; Wagner, Jasenka; Pavlinić, Dinko; Dahoun, Sophie; Bena, Frédérique; Čulić, Vida

    2012-01-01

    The aims of the present study were to assess (1) the parental origin of trisomy 21 and the stage in which nondisjunction occurs and (2) the relationship between altered genetic recombination and maternal age as risk factors for trisomy 21. The study included 102 cases with Down syndrome from the Croatian population. Genotyping analyses were performed by polymerase chain reaction using 11 short tandem repeat markers along chromosome 21q. The vast majority of trisomy 21 was of maternal origin (93%), followed by paternal (5%) and mitotic origin (2%). The frequencies of maternal meiotic I (MI) and meiotic II errors were 86% and 14%, respectively. The highest proportion of cases with zero recombination was observed among those with maternal MI derived trisomy 21. A higher proportion of telomeric exchanges were presented in cases with maternal MI errors and cases with young mothers, although these findings were not statistically significant. The present study is the first report examining parental origin and altered genetic recombination as a risk factor for trisomy 21 in a Croatian population. The results support that trisomy 21 has a universal genetic etiology across different human populations. PMID:21861707

  9. Down syndrome: parental origin, recombination, and maternal age.

    PubMed

    Vraneković, Jadranka; Božović, Ivana Babić; Grubić, Zorana; Wagner, Jasenka; Pavlinić, Dinko; Dahoun, Sophie; Bena, Frédérique; Culić, Vida; Brajenović-Milić, Bojana

    2012-01-01

    The aims of the present study were to assess (1) the parental origin of trisomy 21 and the stage in which nondisjunction occurs and (2) the relationship between altered genetic recombination and maternal age as risk factors for trisomy 21. The study included 102 cases with Down syndrome from the Croatian population. Genotyping analyses were performed by polymerase chain reaction using 11 short tandem repeat markers along chromosome 21q. The vast majority of trisomy 21 was of maternal origin (93%), followed by paternal (5%) and mitotic origin (2%). The frequencies of maternal meiotic I (MI) and meiotic II errors were 86% and 14%, respectively. The highest proportion of cases with zero recombination was observed among those with maternal MI derived trisomy 21. A higher proportion of telomeric exchanges were presented in cases with maternal MI errors and cases with young mothers, although these findings were not statistically significant. The present study is the first report examining parental origin and altered genetic recombination as a risk factor for trisomy 21 in a Croatian population. The results support that trisomy 21 has a universal genetic etiology across different human populations. PMID:21861707

  10. 77 FR 50704 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... a meeting of the National Advisory Council on Aging. The meeting will be open to the public as... privacy. Name of Committee: National Advisory Council on Aging. Date: September 18-19, 2012....

  11. 77 FR 24727 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... a meeting of the National Advisory Council on Aging. The meeting will be open to the public as... privacy. Name of Committee: National Advisory Council on Aging. Date: May 22-23, 2012. Closed: May...

  12. 78 FR 50068 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... a meeting of the National Advisory Council on Aging. The meeting will be open to the public as... privacy. Name of Committee: National Advisory Council on Aging. Date: September 17-18, 2013....

  13. 78 FR 24224 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-24

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... a meeting of the National Advisory Council on Aging. The meeting will be open to the public as... privacy. Name of Committee: National Advisory Council on Aging. Date: June 4-5, 2013. Closed: June 4,...

  14. 75 FR 49499 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-13

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... a meeting of the National Advisory Council on Aging. The meeting will be open to the public as... Committee: National Advisory Council on Aging. Date: September 21-22, 2010. Closed: September 21, 2010, 3...

  15. 75 FR 18511 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-12

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... a meeting of the National Advisory Council on Aging. The meeting will be open to the public as... privacy. Name of Committee: National Advisory Council on Aging. Date: May 25-26, 2010. Closed: May...

  16. 75 FR 77887 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-14

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... a meeting of the National Advisory Council on Aging. The meeting will be open to the public as... privacy. Name of Committee: National Advisory Council on Aging. Date: January 25-26, 2011. Closed:...

  17. 77 FR 76054 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... a meeting of the National Advisory Council on Aging. The meeting will be open to the public as... privacy. Name of Committee: National Advisory Council on Aging. Date: January 29-30, 2013. Closed:...

  18. Photocopy of drawing (original located at the National Archives, San ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (original located at the National Archives, San Bruno, California, Navy # A1-3). Ordnance Dept. of Navy Yard Mare Island "Magazine no. 1 - general plan of proposal. September, 1901 - Mare Island Naval Shipyard, Magazine No. 1, Railroad Avenue, west side near Maseda Road, Vallejo, Solano County, CA

  19. 2. Photocopy of photograph (original print located at Prescott National ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Photocopy of photograph (original print located at Prescott National Forest, 344 South Cortez Street, Prescott, Arizona). Photograph is an enlargement of the negative. Photographer unknown, 1926 'TONTO RANGER STATION PRESCOTT N.F. 1926.' VIEW LOOKING SOUTH. FROM LEFT TO RIGHT: HOUSE, WINDMILL, WATER STORAGE TANK, GARAGE, BARN. - Tonto Ranger Station, Forest Service Road 65 at Tonto Wash, Skull Valley, Yavapai County, AZ

  20. 1. Photocopy of photograph (original print located at Prescott National ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopy of photograph (original print located at Prescott National Forest, 344 South Cortez Street, Prescott, Arizona). Photograph is an enlargement of the negative. Photographer unknown, 1946 'TONTO SPRINGS CABIN PRESCOTT N.F. - 1946.' VIEW LOOKING NORTH. - Tonto Ranger Station, Forest Service Road 65 at Tonto Wash, Skull Valley, Yavapai County, AZ

  1. 4. Photocopy of drawing (Original in collection of the National ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photocopy of drawing (Original in collection of the National Archives) John A. Lane, 12/15/1927 PROPOSED REHABILITATION PLAN FOR U.S. CUSTOM HOUSE, FIRST FLOOR - U. S. Custom House, Whirlpool Street at Lower Arch Bridge, Niagara Falls, Niagara County, NY

  2. 6. Photocopy of drawing (Original in collection of the National ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photocopy of drawing (Original in collection of the National Archives) John A. Lane, 12/15/1927 PROPOSED REHABILITATION PLAN FOR U.S. CUSTOM HOUSE, SOUTH AND NORTH ELEVATIONS - U. S. Custom House, Whirlpool Street at Lower Arch Bridge, Niagara Falls, Niagara County, NY

  3. 3. Photocopy of drawing (Original in collection of the National ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Photocopy of drawing (Original in collection of the National Archives) John A. Lane, 12/15/1927 PROPOSED REHABILITATION PLAN FOR U.S. CUSTOM HOUSE, BASEMENT - U. S. Custom House, Whirlpool Street at Lower Arch Bridge, Niagara Falls, Niagara County, NY

  4. 5. Photocopy of drawing (Original in collection of the National ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photocopy of drawing (Original in collection of the National Archives) John A. Lane, 12/15/1927 PROPOSED REHABILITATION PLAN FOR U.S. CUSTOM HOUSE, WHIRLPOOL STREET AND EAST ELEVATIONS - U. S. Custom House, Whirlpool Street at Lower Arch Bridge, Niagara Falls, Niagara County, NY

  5. 76 FR 20360 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-12

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... a meeting of the National Advisory Council on Aging. The meeting will be open to the public as... on Aging. Date: May 24-25, 2011. Closed: May 24, 2011, 3 p.m. to 5 p.m. Agenda: To review...

  6. 76 FR 27336 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... conducted by the National Institute on Aging, including consideration of personnel qualifications and... Institute on Aging, Biomedical Research Center, 251 Bayview Boulevard, 3rd Floor Conference Room,...

  7. 77 FR 19675 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-02

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... conducted by the National Institute on Aging, including consideration of personnel qualifications and... Institute on Aging, Biomedical Research Center, 251 Bayview Boulevard, 3rd Floor Conference Room,...

  8. 75 FR 17149 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-05

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... conducted by the National Institute on Aging, including consideration of personnel qualifications and... Institute on Aging, Biomedical Research Center, 251 Bayview Boulevard, 3rd Floor Conference Room,...

  9. 76 FR 78285 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-16

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... a meeting of the National Advisory Council on Aging. The meeting will be open to the public as... on Aging. Date: January 24-25, 2012. ] Closed: January 24, 2012, 3 p.m. to 5 p.m. Agenda: To...

  10. 76 FR 46823 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... a meeting of the National Advisory Council on Aging. The meeting will be open to the public as... on Aging. Date: September 20-21, 2011. Closed: September 20, 2011, 3 p.m. to 5 p.m. Agenda: To...

  11. 78 FR 16858 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-19

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... conducted by the National Institute on Aging, including consideration of personnel qualifications and... Institute on Aging, Biomedical Research Center, 251 Bayview Blvd., 3rd Floor, Conference Room...

  12. 77 FR 55849 - National Institute on Aging; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Meeting Pursuant to... conducted by the National Institute on Aging, including consideration of personnel qualifications and... Institute on Aging, Biomedical Research Center, 251 Bayview Boulevard, 3rd Floor Conference Room,...

  13. Photocopy of photograph (original photograph located in National Park Service, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of photograph (original photograph located in National Park Service, U.S.S. Arizona Memorial, 14th Naval District Photograph Collection), 14th ND PHOG no. PH 00-46. U.S. Navy photograph, 1946. FACILITY 250 AT MAKALAPA WITH ADDED WOOD-FRAMED STORIES. - U.S. Naval Base, Pearl Harbor, Headquarters, Commander-in-Chief of the Pacific Fleet, Intersection of Halawa & Makalapa Drives, Makalapa Administration Area, Pearl City, Honolulu County, HI

  14. Photocopy of photograph (original photograph located in National Park Service, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of photograph (original photograph located in National Park Service, U.S.S. Arizona Memorial, 14th Naval District Photograph Collection), PHOG No. P.H. 3470-42. U.S. Navy photograph, August 1942. INTERIOR VIEW OF THE HOSPITAL POINT POWER PLANT (FACILITY 177). - U.S. Naval Base, Pearl Harbor, Bombproof Facilities, Various locations throughout base, Pearl City, Honolulu County, HI

  15. Photocopy of photograph (original photograph located in National Park Service, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of photograph (original photograph located in National Park Service, U.S.S. Arizona Memorial, 14th Naval District Photograph Collection), PHOG No. P.H. 3309-42. U.S. Navy photograph, 1942. BEGINNING CONSTRUCTION ON THE BOMBPROOF POWER PLANT (FACILITY 177) AT HOSPITAL POINT. - U.S. Naval Base, Pearl Harbor, Bombproof Facilities, Various locations throughout base, Pearl City, Honolulu County, HI

  16. Photocopy of photograph (original photograph located in the National Park ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of photograph (original photograph located in the National Park Service, U.S.S. Arizona Memorial, 14th Naval District Photograph Collection), 14th ND PHOG No. P.H. 4175-42. U.S. Navy photograph, 1942. THE NAVAL SUPPLY DEPOT’S HUGE FUELING PIER (FACILITY H1-H4) HELPED KEEP THE FLEET MOVING DURING WORLD WAR II. - U.S. Naval Base, Pearl Harbor, Waterfront Facilities, Various locations throughout base, Pearl City, Honolulu County, HI

  17. Origin and Age of the Yemi Limestone Breccia, Korea

    NASA Astrophysics Data System (ADS)

    KOH, Hee Jae

    2015-04-01

    The Yemi Limestone Breccia (YLB), which has been argued for its age and depositional origin, occurs sporadically in the upper part of the Cambro-Ordovician Chosun Supergroup (CS) in Korean Peninsula. The YLB is characterized by a carbonate breccia with calcareous and carbonaceous shale matrix. Based on occurrence and composition of breccia and matrix, the YLB can be classified into Type-I and Type-II carbonate breccia. Type-I carbonate breccia comprises dark gray to light gray limestone and lime-mudstone breccia with calcareous matrix and is commonly constrained within the upper part of the CS as a lens-shaped zonal occurrence. The Type-I carbonate breccia results in syn-depositional solution-collapsed brecciation through karstification during intermittent subareal exposure of platform carbonate in Middle Ordovician. Type-II carbonate breccia mainly occurs in the uppermost part of the CS showing an irregular-shaped distribution rather than sheet-like layering parallel to bedding. Type-II carbonate breccia consists of gray to dark gray limestone and lime-mudstone breccia and shale matrix. Matrix is typically purple to reddish and gray to dark gray shale with minor amount of sandstone, and partly carbonaceous indicating organic origin. Most of Type-II carbonate breccia is morphologically classified into chaotic breccia. Matrix and breccia display considerable difference of composition and deformational structures. Breccia preserves various penetrative ductile to brittle deformation structures such as cleavage superimposing bedding, minor fold structure, minor faults crosscutting both dolomite and calcite veins, and fracture zones filled in calcite. However, these deformational structures of breccia do not continuously extended into matrix. Especially Type-II carbonate breccia is well observed in limestone of the lower part of unconformity between CS and clastic rocks of the Jurassic Bansong Group (BS). Fractured and solution zones of brecciated limestone of the CS

  18. 78 FR 69432 - National Institute on Aging; Cancellation of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-19

    ... November 8, 2013, 67177 FR 217. The meeting was entitled Member Conflict. Dated: November 13, 2013. Melanie... HUMAN SERVICES National Institutes of Health National Institute on Aging; Cancellation of Meeting Notice is hereby given of the cancellation of the National Institute on Aging Special Emphasis...

  19. 77 FR 40368 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel Age, Gene/Environment Susceptibility... evaluate contract proposals. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin...

  20. 27 CFR 5.52 - Certificates of age and origin.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) Scotch, Irish, and Canadian whiskies. Scotch, Irish, and Canadian whiskies, imported in bottles, shall... government must certify to the age of the youngest distilled spirits in the bottle. The age certified shall... customarily stored in oak containers) or Cognac, imported in bottles, shall not be released from...

  1. Psychological Studies of Aging: Their Origins, Development and Present Challenge.

    ERIC Educational Resources Information Center

    Welford, A. T.

    1992-01-01

    Considers needs and potentialities for application of fundamental psychological knowledge of aging in areas of industrial and other work, clinical assessment and intelligence testing, assessment of attitudes, and coping with everyday problems in old age and with interpersonal relationships, especially in old people's communities and between old…

  2. Motor Fitness of Mentally Retarded Boys to National Age Norms.

    ERIC Educational Resources Information Center

    Brace, D. K.

    The study compared the physical fitness of 65 mentally retarded boys (mean age 14-years, mean IQ 60) at Austin (Texas) State School with national age scales for boys of the same chronological ages on the American Association for Health, Physical Education and Recreation Youth Fitness Test, which measures strength, speed, agility, power,…

  3. The origins of age-related proinflammatory state.

    PubMed

    Ferrucci, Luigi; Corsi, Annamaria; Lauretani, Fulvio; Bandinelli, Stefania; Bartali, Benedetta; Taub, Dennis D; Guralnik, Jack M; Longo, Dan L

    2005-03-15

    We hypothesized that the rising levels of inflammatory markers with aging is explained by cardiovascular risk factors and morbidity becoming progressively more prevalent in older persons. Information on inflammatory markers, cardiovascular risk factors, and diseases was collected in 595 men and 748 women sampled from the general population (age, 20-102 years). In both men and women, older age was associated with higher levels of interleukin-6 (IL-6), IL-1 receptor antagonist (IL-1ra), IL-18, C-reactive protein (CRP), and fibrinogen, while soluble IL-6 receptor (sIL-6r) increased significantly with age only in men. Adjusting for cardiovascular risk factors and morbidity, the age regression coefficients became substantially smaller in models predicting IL-6, IL-1ra, IL-18, and fibrinogen and larger in the model predicting sIL6r. Adjustment for cardiovascular morbidity substantially reduced the effect of age on CRP in men but not in women. Findings were confirmed in a subgroup of 51 men and 45 women with low risk profile and no cardiovascular morbidity. Part of the "proinflammatory state" in older persons is related to the high prevalence of cardiovascular risk factor and morbidity. PMID:15572589

  4. NATIONAL AGING PROGRAMS INFORMATION SYSTEM (NAPIS)

    EPA Science Inventory

    The 1992 reauthorization of the Older Americans Act (OAA) directed the Administration on Aging to improve performance reporting on programs and services funded by the OA This impetus caused AoA to reconsider reporting requirements for all Titles of the Act under the direction of ...

  5. Tungsten isotopic constraints on the age and origin of chondrules

    PubMed Central

    Kleine, Thorsten; Kruijer, Thomas S.; Burkhardt, Christoph; Metzler, Knut

    2016-01-01

    Chondrules may have played a critical role in the earliest stages of planet formation by mediating the accumulation of dust into planetesimals. However, the origin of chondrules and their significance for planetesimal accretion remain enigmatic. Here, we show that chondrules and matrix in the carbonaceous chondrite Allende have complementary 183W anomalies resulting from the uneven distribution of presolar, stellar-derived dust. These data refute an origin of chondrules in protoplanetary collisions and, instead, indicate that chondrules and matrix formed together from a common reservoir of solar nebula dust. Because bulk Allende exhibits no 183W anomaly, chondrules and matrix must have accreted rapidly to their parent body, implying that the majority of chondrules from a given chondrite group formed in a narrow time interval. Based on Hf-W chronometry on Allende chondrules and matrix, this event occurred ∼2 million years after formation of the first solids, about coeval to chondrule formation in ordinary chondrites. PMID:26929340

  6. Tungsten isotopic constraints on the age and origin of chondrules

    NASA Astrophysics Data System (ADS)

    Budde, Gerrit; Kleine, Thorsten; Kruijer, Thomas S.; Burkhardt, Christoph; Metzler, Knut

    2016-03-01

    Chondrules may have played a critical role in the earliest stages of planet formation by mediating the accumulation of dust into planetesimals. However, the origin of chondrules and their significance for planetesimal accretion remain enigmatic. Here, we show that chondrules and matrix in the carbonaceous chondrite Allende have complementary 183W anomalies resulting from the uneven distribution of presolar, stellar-derived dust. These data refute an origin of chondrules in protoplanetary collisions and, instead, indicate that chondrules and matrix formed together from a common reservoir of solar nebula dust. Because bulk Allende exhibits no 183W anomaly, chondrules and matrix must have accreted rapidly to their parent body, implying that the majority of chondrules from a given chondrite group formed in a narrow time interval. Based on Hf-W chronometry on Allende chondrules and matrix, this event occurred ˜2 million years after formation of the first solids, about coeval to chondrule formation in ordinary chondrites.

  7. 27 CFR 5.52 - Certificates of age and origin.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... be the period during which, after distillation and before bottling, the distilled spirits have been... rum in the bottle. The age certified shall be the period during which, after distillation and before... which the Tequila has been stored in oak containers after distillation and before bottling. (d)...

  8. 77 FR 9670 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-17

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's Prevention. Date: March 1, 2012...., Scientific Review Officer, National Institute on Aging, Scientific Review Branch, Gateway Building...

  9. 77 FR 2737 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Development and Maintenance of a... and evaluate contract proposals. Place: National Institute on Aging, Gateway Building, 7201...

  10. 77 FR 50704 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Drug Development for Alzheimer's Disease... applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite...

  11. 75 FR 4829 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-29

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Development and Maintenance of a... contract proposals. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Ave, Suite...

  12. 78 FR 63999 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's Disease Sequencing Project. Date...., Scientific Review Officer, Scientific Review Branch, National Institute on Aging, Gateway Building,...

  13. Aging, Research on Aging, and National Policy: A Conversation with Robert Butler.

    ERIC Educational Resources Information Center

    VandenBos, Gary R.; Buchanan, Joan

    1983-01-01

    The former director of the National Institute on Aging (NIA) discusses: consequences of aging in relation to Federal policies; care facilities for older persons; the role of the Federal government in funding aging research; and the need for more personnel trained to deal with problems of the elderly. (AOS)

  14. Temperamental Origins of Child and Adolescent Behavior Problems: From Age Three to Age Fifteen.

    ERIC Educational Resources Information Center

    Caspi, Avshalom; And Others

    1995-01-01

    Assessed relationships between early temperament and behavior problems in a longitudinal study of 850 children from age 3 to 15. Temperament dimensions at ages 3 and 5 were correlated in theoretically coherent ways with behavior problems that were independently evaluated by parents and teachers at ages 9 and 11 and by parents as ages 13 and 15.…

  15. Origin and relative age of lunar and Mercurian intercrater plains

    NASA Technical Reports Server (NTRS)

    Strom, R. G.

    1977-01-01

    Differences in the diameter/density distribution of craters in the size range 7-100 km between heavily cratered areas and areas of intercrater plains indicate the deposition of both lunar and Mercurian intercrater plains has preferentially obliterated craters not greater than about 30 km diameter. This obliteration has altered the original lunar population distribution function from about a -1.3 slope to about -0.7 slope. At least a significant portion of both the lunar and Mercurian intercrater plains appear to be volcanic deposits emplaced during the later stages of heavy bombardment on each body rather than basin ejecta or an ancient primordial surface. The very widespread distribution of intercrater plains on Mercury compared to the moon may be related to Mercury's core formation which would have resulted in a large radius increase leading to widespread extensional fracturing to provide egress for the eruption of volcanic deposits on a global scale. This was followed by a radius decrease due to contraction of the lithosphere to produce thrust faulting represented by Mercury's lobate scarps.

  16. Ages at a Crime Scene: Simultaneous Estimation of the Time since Deposition and Age of Its Originator.

    PubMed

    Agudelo, Juliana; Halámková, Lenka; Brunelle, Erica; Rodrigues, Roselyn; Huynh, Crystal; Halámek, Jan

    2016-06-21

    Blood is a major contributor of evidence in investigations involving violent crimes because of the unique composition of proteins and low molecular weight compounds present in the circulatory system, which often serve as biomarkers in clinical diagnostics. It was recently shown that biomarkers present in blood can also identify characteristics of the originator, such as ethnicity and biological sex. A biocatalytic assay for on-site forensic investigations was developed to simultaneously identify the age range of the blood sample originator and the time since deposition (TSD) of the blood spot. For these two characteristics to be identified, the levels of alkaline phosphatase (ALP), a marker commonly used in clinical diagnostics corresponding to old and young originators, were monitored after deposition for up to 48 h to mimic a crime scene setting. ALP was chosen as the biomarker due to its age-dependent nature. The biocatalytic assay was used to determine the age range of the originator using human serum samples. By means of statistical tools for evaluation and the physiological levels of ALP in healthy people, the applicability of this assay in forensic science was shown for the simultaneous determination of the age of the originator and the TSD of the blood spot. The stability of ALP in serum allows for the differentiation between old and young originators up to 2 days after the sample was left under mimicked crime scene conditions. PMID:27212711

  17. The origins of age of acquisition and typicality effects: Semantic processing in aphasia and the ageing brain.

    PubMed

    Räling, Romy; Schröder, Astrid; Wartenburger, Isabell

    2016-06-01

    Age of acquisition (AOA) has frequently been shown to influence response times and accuracy rates in word processing and constitutes a meaningful variable in aphasic language processing, while its origin in the language processing system is still under debate. To find out where AOA originates and whether and how it is related to another important psycholinguistic variable, namely semantic typicality (TYP), we studied healthy, elderly controls and semantically impaired individuals using semantic priming. For this purpose, we collected reaction times and accuracy rates as well as event-related potential data in an auditory category-member-verification task. The present results confirm a semantic origin of TYP, but question the same for AOA while favouring its origin at the phonology-semantics interface. The data are further interpreted in consideration of recent theories of ageing. PMID:27106392

  18. The Emergence of Beliefs about the Origins of Species in School-Age Children.

    ERIC Educational Resources Information Center

    Evans, E. Margaret

    2000-01-01

    Examined 5- to 12-year-olds' emerging understanding of the origins of species in two studies. Demonstrated systematic developmental pattern in children's explanations for biological origins. Found age-related shifts from mixed creationist and spontaneous generationist explanations, to exclusive creationism, and finally to evolutionist or…

  19. 77 FR 61613 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ... Committee: National Institute on Aging Special Emphasis Panel; Systems Biology of the Aged in Yeast. Date...: National Institute on Aging Special Emphasis Panel; ROS and Aging II. Date: November 7, 2012. Time: 12:30...

  20. 75 FR 56119 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Initial Review Group; Behavior and Social Science of Aging Review...: Jeannette L. Johnson, PhD, Scientific Review Officer, National Institutes on Aging, National Institutes...

  1. 77 FR 24969 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-26

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Initial Review Group; Behavior and Social Science of Aging Review.... Johnson, Ph.D., Scientific Review Officer, National Institutes on Aging, National Institutes of...

  2. 76 FR 24901 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-03

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Initial Review Group, Behavior and Social Science of Aging Review...: Jeannette L. Johnson, PhD, Scientific Review Officer, National Institute on Aging, National Institutes...

  3. 77 FR 6129 - National Institute on Aging Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging Notice of Closed Meetings... Committee: National Institute on Aging Initial Review Group; Behavior and Social Science of Aging Review...: Jeannette L. Johnson, Ph.D., Scientific Review Officer, National Institutes on Aging, National Institutes...

  4. 77 FR 53207 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-31

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Initial Review Group, Behavior and Social Science of Aging Review...: Jeannette L. Johnson, Ph.D., Scientific Review Officer, National Institutes on Aging, National Institutes...

  5. 76 FR 69328 - Proposed Collection; Comment Request; Race and National Origin Identification

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-08

    ... Proposed Collection; Comment Request; Race and National Origin Identification AGENCY: Department of The.... Type of Review: Revision of a currently approved collection. Title: Race and National Origin Identification. Abstract: The Department's automated recruitment system, CareerConnector, is used to capture...

  6. The Origins of Journalism Education: A Cross-National Perspective.

    ERIC Educational Resources Information Center

    Altschull, J. Herbert

    Differences in journalism education across the world reflect differences in political, economic, and social environments. Journalism education in the United States, which began in the age of progressivism and reflected the values of the time, has emphasized the press's objectivity and independence, an independence built on its reliance on…

  7. The developmental aging and origins of health and disease hypotheses explained by different protein networks.

    PubMed

    Feltes, Bruno César; de Faria Poloni, Joice; Bonatto, Diego

    2011-08-01

    One theory that attempts to explain how and why an organism ages is the developmental hypothesis of aging (DevAge), which describes how developmental programming leads to aging in adults. Interestingly, the developmental origins of health and disease hypothesis (DOHaD) asserts that some aging-associated diseases that occur in adults are closely related to development and to conditions in the intrauterine environment. Thus, both aging and aging-associated diseases can be viewed, at least in part, as the result of a developmental program that is activated early in embryogenesis and persists throughout the lifespan of the organism. We would expect this developmental program to be regulated by a set of interacting protein networks that connect environmental and molecular signals. However, the connection between aging and development is not clear. Thus, a systems biology approach that incorporates different "omic" databases for two mammalian models, Homo sapiens and Mus musculus, was used to evaluate how development and aging are interconnected. Interestingly, three major, evolutionarily conserved processes, namely the immune system, epigenetics, and aerobic metabolism, appear to regulate aging and development in both H. sapiens and M. musculus. Considering that these three processes are essential to embryogenesis, the protein networks within these processes are subjected to strong selective pressure to eliminate gross developmental abnormalities in early embryogenesis. This selective pressure becomes more relaxed in the adult organism, permitting the onset of aging-associated diseases and inflammation-related aging; this concept echoes the antagonistic pleiotropy hypothesis of aging. PMID:21380541

  8. Prediction of Elderly Anthropometric Dimension Based On Age, Gender, Origin, and Body Mass Index

    NASA Astrophysics Data System (ADS)

    Indah, P.; Sari, A. D.; Suryoputro, M. R.; Purnomo, H.

    2016-01-01

    Introduction: Studies have indicated that elderly anthropometric dimensions will different for each person. To determine whether there are differences in the anthropometric data of Javanese elderly, this study will analyze whether the variables of age, gender, origin, and body mass index (BMI) have been associated with elderly anthropometric dimensions. Age will be divided into elderly and old categories, gender will divide into male and female, origins were divided into Yogyakarta and Central Java, and for BMI only use the normal category. Method: Anthropometric studies were carried out on 45 elderly subjects in Sleman,Yogyakarta. Results and Discussion: The results showed that some elderly anthropometric dimensions were influenced by age, origin, and body mass index but gender doesn't significantly affect the elderly anthropometric dimensions that exist in the area of Sleman. The analysis has provided important aid when designing products that intended to the Javanese elderly Population.

  9. 78 FR 55752 - National Institute On Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-11

    ... HUMAN SERVICES National Institutes of Health National Institute On Aging; Notice of Closed Meeting... Committee: National Institute on Aging Initial Review Group, Behavior and Social Science of Aging Review...: Rebecca J. Ferrell, Ph.D., Scientific Review Officer, National Institute on Aging, Gateway Building,...

  10. 76 FR 24890 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-03

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Initial Review Group, Biological Aging Review Committee. Date: June 1..., PhD, Scientific Review Officer, Scientific Review Branch, National Institute on Aging, Gateway...

  11. 76 FR 6628 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Initial Review Group; Behavior and Social Science of Aging Review... Person: Jeannette L. Johnson, PhD, Scientific Review Officer, National Institutes On Aging,...

  12. 78 FR 51195 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-20

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Initial Review Group; Biological Aging Review Committee Date: October... Nakhai, Ph.D., Scientific Review Branch, National Institute On Aging, Gateway Bldg., 2C212,...

  13. 78 FR 20669 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-05

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Management of the Primate Aging Database Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  14. 75 FR 79386 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Hormone Therapy and Cognitive Aging. Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  15. 76 FR 3148 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-19

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Initial Review Group; Biological Aging Review Committee. Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  16. 77 FR 34394 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Healthy Aging and the Life Course. Date: June...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  17. 75 FR 39698 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-12

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel, Network Infrastructure for Aging Research...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  18. 75 FR 63497 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Genetic Determinants of Healthy Aging. Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  19. 77 FR 14026 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-08

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Reprogramming, Aging and Alzheimer's Disease... Lewis, Ph.D., Scientific Review Branch, National Institute on Aging, Gateway Building, Suite 2C212,...

  20. 75 FR 43995 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-27

    ... Committee: National Institute on Aging Special Emphasis Panel, Healthy Aging; Search for Mechanisms. Date... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  1. 77 FR 33475 - National Institute On Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-06

    ... Committee: National Institute on Aging Special Emphasis Panel; Healthy Aging and the Life Course. Date: June... HUMAN SERVICES National Institutes of Health National Institute On Aging; Notice of Closed Meetings...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  2. 75 FR 22411 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ... Committee: National Institute on Aging Special Emphasis Panel; Healthy Aging Pathways. Date: June 18, 2010... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Lead Drug Candidates. Date: May 14,...

  3. 78 FR 59042 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-25

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Cultivating Health and Aging Researchers.... Place: National Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda,...

  4. 78 FR 66032 - National Institute On Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-04

    ... HUMAN SERVICES National Institutes of Health National Institute On Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Optogenetics Utilization in Models of Aging... evaluate grant applications. Place: National Institute on Aging, Gateway Building, Suite 2C212,...

  5. 75 FR 61766 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-06

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel, Cartilage Aging and Osteoarthritis. Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  6. 78 FR 27977 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-13

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Initial Review Group; Behavior and Social Science of Aging Review...: Rebecca Jo Ferrell, Ph.D., Scientific Review Branch, National Institute on Aging, Gateway Building,...

  7. 76 FR 6628 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Sex Differences in Health and Survival. Date..., Scientific Review Officer, National Institutes on Aging, National Institutes of Health, 7201 Wisconsin...

  8. 75 FR 57965 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Member Conflict SEP. Date: October 4, 2010... Review Branch, National Institute on Aging, National Institutes of Health, 7201 Wisconsin Avenue,...

  9. 75 FR 35821 - National Institute On Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-23

    ... HUMAN SERVICES National Institutes of Health National Institute On Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel Member Conflict SEP, Date: June 24, 2010. Time...: Ramesh Vemuri, PhD, Chief, Scientific Review Branch, National Institute on Aging, National Institutes...

  10. A Dimensional Liability Model of Age Differences in Mental Disorder Prevalence: Evidence from a National Sample

    PubMed Central

    Hoertel, Nicolas; McMahon, Kibby; Olfson, Mark; Wall, Melanie M.; Rodríguez-Fernández, Jorge Mario; Lemogne, Cédric; Limosin, Frédéric; Blanco, Carlos

    2015-01-01

    Recent theories have proposed a metastructure that organizes related mental disorders into broad dimensions of psychopathology (i.e., internalizing and externalizing dimensions). Prevalence rates of most mental disorders, when examined independently, are substantially lower in older than in younger adults, which may affect this metastructure. Within a nationally representative sample, the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC; N = 43,093), we developed a dimensional liability model of common psychiatric disorders to clarify whether aging affects specific disorders or general dimensions of psychopathology. Significant age differences existed across age groups (18-24, 25-34, 35-44, 45-54, 55-64, 65-75 and 75+), such that older adults showed lower prevalence rates of most disorders compared to younger adults. We next investigated patterns of disorder comorbidity for past-year psychiatric disorders and found that a distress-fear-externalizing liability model fit the data well. This model was age-group invariant and indicated that that the observed lower prevalence of mental disorders with advancing age originates from lower average means on externalizing and internalizing liability dimensions. This unifying dimensional liability model of age and mental disorder comorbidity can help inform the role of aging on mental disorder prevalence for research and intervention efforts, and service planning for the impending crisis in geriatric mental health. PMID:25858414

  11. A dimensional liability model of age differences in mental disorder prevalence: evidence from a national sample.

    PubMed

    Hoertel, Nicolas; McMahon, Kibby; Olfson, Mark; Wall, Melanie M; Rodríguez-Fernández, Jorge Mario; Lemogne, Cédric; Limosin, Frédéric; Blanco, Carlos

    2015-05-01

    Recent theories have proposed a metastructure that organizes related mental disorders into broad dimensions of psychopathology (i.e., internalizing and externalizing dimensions). Prevalence rates of most mental disorders, when examined independently, are substantially lower in older than in younger adults, which may affect this metastructure. Within a nationally representative sample, the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC; N = 43,093), we developed a dimensional liability model of common psychiatric disorders to clarify whether aging affects specific disorders or general dimensions of psychopathology. Significant age differences existed across age groups (18-24, 25-34, 35-44, 45-54, 55-64, 65-75 and 75+), such that older adults showed lower prevalence rates of most disorders compared to younger adults. We next investigated patterns of disorder comorbidity for past-year psychiatric disorders and found that a distress-fear-externalizing liability model fit the data well. This model was age-group invariant and indicated that the observed lower prevalence of mental disorders with advancing age originates from lower average means on externalizing and internalizing liability dimensions. This unifying dimensional liability model of age and mental disorder comorbidity can help inform the role of aging on mental disorder prevalence for research and intervention efforts, and service planning for the impending crisis in geriatric mental health. PMID:25858414

  12. Instant zero, myth or reality? Age and origin of the universe

    NASA Astrophysics Data System (ADS)

    Acker, Agnes

    1989-04-01

    Theories relating to the architecture, origin, and age of the universe are reviewed. Models for a cooling and expanding universe are supported by such experimental findings as the discovery of 2.7-K thermal radiation and the determination of the cosmological abundances of elements. Measurememts of cosmological heavy nuclei have led to a Galactic age estimation of 7-15 billion years, while astrophysical calculations based upon observed luminosities have led to an age estimation for globular clusters (the oldest objects in the Galaxy) of 13-19 billion years old. Implications of the Big Bang theory are considered.

  13. Social Origin and Graduation Age: A Cohort Comparison of Danish University Students

    ERIC Educational Resources Information Center

    Klausen, Trond Beldo

    2016-01-01

    This paper investigates whether social origin has an impact on graduation age among university students. A large number of social background factors are applied on a large data set of 4 successive cohorts of Danish university graduates born 1960-1975. These are cohorts for whom university attendance increased steeply. Contrary to recent findings…

  14. Rural origin, age, and endoparasite fecal prevalence in dogs surrendered to the Regina Humane Society, 2013

    PubMed Central

    Schurer, Janna M.; Hamblin, Brie; Davenport, Laura; Wagner, Brent; Jenkins, Emily J.

    2014-01-01

    We report the results of fecal parasite surveillance in dogs surrendered to the Regina Humane Society, Saskatchewan, Canada, between May and November 2013. Overall, 23% of 231 dogs were infected with at least 1 intestinal parasite. Endoparasite infection was positively associated with rural origin (P = 0.002) and age (< 12 months; P < 0.001). PMID:25477549

  15. Land Application of Wastewater Sludges: A National Science Foundation Student-Originated Studies Project.

    ERIC Educational Resources Information Center

    Bender, Timothy J.; Barnard, Walther M.

    1981-01-01

    Summarizes a student-originated studies project, funded by the National Science Foundation, on land application of wastewater sludges. Describes the students' proposal, research methods, and evaluation of the project. (DS)

  16. Arrogant Assimilationism: National Identity Politics and African-Origin Muslim Girls in the Other France

    ERIC Educational Resources Information Center

    Keaton, Trica

    2005-01-01

    National identity politics in France have taken an interesting turn since the 1980s, a period accentuated by social movements led by youth of immigration who self-asserted in terms of ethnonational origins. Now French-born or -raised youth, stigmatized by those origins, self-identify as French, although they are not so perceived in French society.…

  17. The origins and early history of the National Chiropractic Association

    PubMed Central

    Keating, Joseph C; Rehm, William S

    1993-01-01

    Early organization in chiropractic was prompted by the profession’s need to promote itself and to defend against the onslaught of political medicine and organized osteopathy. The first priorities were legal defense against prosecution for unlicensed practice and malpractice insurance. The Universal Chiropractors’ Association (UCA), organized at the Palmer School of Chiropractic (PSC) in 1906, sought to meet these needs by insuring its members and by developing a legal department under the supervision of attorney Tom Morris, one time lieutenant governor of Wisconsin. The public relations and marketing needs of chiropractors were largely served by the PSC and its legendary leader. However, as chiropractors increasingly sought to avoid prosecution by passage of chiropractic laws, Palmer’s efforts to direct this legislation so as to limit chiropractors’ scope of practice increasingly alienated many in the profession. The American Chiropractic Association (ACA) was founded in 1922 to provide a broadscope alternative to BJ’s UCA. With Palmer’s departure from the UCA following the neurocalometer debacle, ACA and UCA sought amalgamation. Simultaneously, organized medicine renewed its attack on the profession by introducing basic science legislation, which prompted chiropractors to try to upgrade and standardize chiropractic education. Early efforts to bring about the needed consensus were centered in the International Chiropractic Congress (ICC), particularly its division of state examining boards. In 1930 the ACA and UCA combined to form the National Chiropractic Association (NCA), and by 1934 the ICC had merged with the NCA to form part of its council structure. With this modicum of solidarity the NCA began the process of educational boot-strapping at its 1935 convention in Los Angeles, when its Committee on Education, a forerunner of today’s Council on Chiropractic Education, was proposed by C.O. Watkins of Montana. ImagesFigure 2Figure 3Figure 4Figure 5

  18. 78 FR 9708 - National Institute on Aging Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-11

    ... Committee: National Institute on Aging Special Emphasis Panel; Comparative Physiology of Aging. Date: March..., elainelewis@nia.nih.gov . (Catalogue of Federal Domestic Assistance Program Nos. 93.866, Aging Research... HUMAN SERVICES National Institutes of Health National Institute on Aging Notice of Closed...

  19. 77 FR 40370 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Aging and Innovation. Date: July 11, 2012... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, (Telephone...

  20. 77 FR 63843 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-17

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Aging and Sleep. Date: November 8, 2012. Time... on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892,...

  1. 75 FR 18513 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-12

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Aging Program Project Review. Date: May 5... Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892...

  2. 76 FR 57064 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Initial Review Group, Clinical Aging Review Committee. Date: October... Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892. Contact...

  3. 75 FR 67381 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-02

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel HIV, HAART and AGING. Date: November 23, 2010... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, (Telephone...

  4. 78 FR 52552 - National Institute on Aging Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-23

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging Notice of Closed Meeting... Committee: National Institute on Aging Initial Review Group, Neuroscience of Aging Review Committee. Date..., johnsonj9@nia.nih.gov . (Catalogue of Federal Domestic Assistance Program Nos. 93.866, Aging...

  5. 76 FR 32977 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-07

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Aging and Economics. Date: June 24, 2011... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892 (Telephone...

  6. 77 FR 58854 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-24

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel Cognitive Aging. Date: November 7, 2012 Time... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892 Contact...

  7. 77 FR 53207 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-31

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Pepper Centers. Date: September 27-28, 2012... Branch, National Institute on Aging, 7201 Wisconsin Avenue, Suite 2c212, Bethesda, MD 20892,...

  8. 76 FR 42719 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-19

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, The NIA Health and Retirement Study. Date.... Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda,...

  9. 76 FR 17929 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-31

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Drug Development for Alzheimer's Disease...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  10. 75 FR 56116 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Alzheimer's Disease Genetics. Date: October 4... Officer, National Institute on Aging, Scientific Review Branch, Gateway Building 2c-212, 7201...

  11. 77 FR 24728 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Health and Well-Being Across Time. Date: May...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  12. 77 FR 34396 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Changing Long Term Care in America. Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  13. 77 FR 31032 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-24

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Network Infrastructure Support. Date: June 7...., Scientific Review Officer, Scientific Review Branch, National Institute on Aging, Gateway Bldg., 2C212,...

  14. 75 FR 25273 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel, Basis of Myocardial Injury in the Elderly...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  15. 76 FR 5391 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Pepper Centers. Date: February 17-18, 2011..., Scientific Review Branch, National Institute on Aging, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  16. 78 FR 51196 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-20

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Juvenile Protective Factors I. Date...: National Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda, MD...

  17. 75 FR 11188 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Beeson Meeting. Date: April 28-29, 2010. Time..., Scientific Review Officer, National Institute on Aging, Scientific Review Branch, Gateway Building...

  18. 77 FR 56856 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's Network. Date: October 4, 2012..., Ph.D., Scientific Review Officer, National Institute On Aging, Scientific Review Branch,...

  19. 76 FR 57064 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, AD Genetics Warehouse. Date: October 7, 2011..., Scientific Review Officer, National Institute on Aging, Scientific Review Branch, Gateway Building...

  20. 77 FR 1941 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-12

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; GEMSSTAR. Date: January 27, 2012. Time: 8 a.m...., Scientific Review Officer, National Institute on Aging, Gateway Building, Rm. 2C212, 7201 Wisconsin...

  1. 75 FR 26268 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel, ARRA--Behavioral Economics C.E.R.--Clinical.... Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C218, Bethesda,...

  2. 75 FR 9908 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-04

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Health, Behavior, and the Gene-Social... applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, RM 2C212,...

  3. 77 FR 74677 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-17

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Cell Dependent and Independent Mechanism... applications. Place: National Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin...

  4. Investigation of chemomarkers of astragali radix of different ages and geographical origin by NMR profiling.

    PubMed

    Zheng, Lu; Wang, Mei; Ibarra-Estrada, Emmanuel; Wu, Changsheng; Wilson, Erica Georgina; Verpoorte, Robert; Klinkhamer, Petrus Gerardus Leonardus; Choi, Young Hae

    2015-01-01

    Astragalus roots from Astragalus membranaceus Bunge or Astragalus membranaceus var. mongholicus (Bunge) Hsiao are among the most popular traditional medicinal plants due to their diverse therapeutic uses based on their tonic, antinephritic, immunostimulant, hepatoprotectant, diuretic, antidiabetic, analgesic, expectorant and sedative properties. Currently, the herb is produced or cultivated in various sites, including 10 different locations in China with very diverse environmental conditions. These differences affect their metabolic pools and consequently their medicinal properties. The comparative metabolic profiling of plants of different geographical origins or ages could contribute to detect biomarkers for their quality control and thus guarantee the efficacy of the herbal medicines produced with this drug. In this paper nuclear magnetic resonance spectroscopy (NMR)-based metabolomics was applied for to plants of different origins and age for this purpose. The results of this study show that in the set of samples evaluated, age is more discriminating than geographical location. The quantity of individual flavonoids and some primary metabolites contributed most to this age differentiation. On the other hand, based on the analysis of orthogonal partial least square (OPLS) modeling, the marker metabolites for the geographical origin were saponins and isoflavonoids. PMID:25690295

  5. National School-Age Child Care Alliance (NSACCA): National Survey Results. Draft Report.

    ERIC Educational Resources Information Center

    Marx, Fern

    Presenting preliminary results of a National School-Age Child Care Alliance study of child care providers, this report is an initial analysis of 250 out of 427 questionnaires received as of April, 1993, representing practitioners in 40 states and 180 cities. Tables present data from responses to 16 items on the questionnaire soliciting information…

  6. Parental age and the origin of trisomy 21. A study of 302 families.

    PubMed

    Dagna Bricarelli, F; Pierluigi, M; Landucci, M; Arslanian, A; Coviello, D A; Ferro, M A; Strigini, P

    1989-04-01

    Several studies have attempted to define the role of parental age in determining the prevalence of 47, +21 according to the origin of nondisjunction. This report analyzes the original data of 197 informative families from Italy and reviews the available literature (96 families from Denmark and 201 from other countries). Mothers whose gametes showed nondisjunction are treated as cases, and those with normal meiosis as controls within each study. To utilize the data fully, maternal age at birth of a 47, +21 individual is treated as a continuous variable in a nonparametric comparison. The combined evidence indicates that nondisjunction in the female is associated with a significant age difference between cases and controls which is mostly due to errors in the second meiotic division. It may be inferred that in the general population, aging enhances nondisjunction at both first and second division in the female, while aging in the male is presumably associated mostly (or only) with first division errors. Implications and alternative models are discussed. PMID:2523851

  7. 77 FR 64525 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-22

    ..., (Telephone Conference Call). Contact Person: Elaine Lewis, Ph.D., Scientific Review Branch, National... Committee: National Institute on Aging Special Emphasis Panel Tuberculosis Infection in the Elderly....

  8. The Age Specific Incidence Anomaly Suggests that Cancers Originate During Development

    NASA Astrophysics Data System (ADS)

    Brody, James P.

    The accumulation of genetic alterations causes cancers. Since this accumulation takes time, the incidence of most cancers is thought to increase exponentially with age. However, careful measurements of the age-specific incidence show that the specific incidence for many forms of cancer rises with age to a maximum, and then decreases. This decrease in the age-specific incidence with age is an anomaly. Understanding this anomaly should lead to a better understanding of how tumors develop and grow. Here we derive the shape of the age-specific incidence, showing that it should follow the shape of a Weibull distribution. Measurements indicate that the age-specific incidence for colon cancer does indeed follow a Weibull distribution. This analysis leads to the interpretation that for colon cancer two subpopulations exist in the general population: a susceptible population and an immune population. Colon tumors will only occur in the susceptible population. This analysis is consistent with the developmental origins of disease hypothesis and generalizable to many other common forms of cancer.

  9. The Age Specific Incidence Anomaly Suggests that Cancers Originate During Development

    NASA Astrophysics Data System (ADS)

    Brody, James P.

    2014-05-01

    The accumulation of genetic alterations causes cancers. Since this accumulation takes time, the incidence of most cancers is thought to increase exponentially with age. However, careful measurements of the age-specific incidence show that the specific incidence for many forms of cancer rises with age to a maximum, and then decreases. This decrease in the age-specific incidence with age is an anomaly. Understanding this anomaly should lead to a better understanding of how tumors develop and grow. Here we derive the shape of the age-specific incidence, showing that it should follow the shape of a Weibull distribution. Measurements indicate that the age-specific incidence for colon cancer does indeed follow a Weibull distribution. This analysis leads to the interpretation that for colon cancer two subpopulations exist in the general population: a susceptible population and an immune population. Colon tumors will only occur in the susceptible population. This analysis is consistent with the developmental origins of disease hypothesis and generalizable to many other common forms of cancer.

  10. Comparable ages for the independent origins of electrogenesis in African and South American weakly electric fishes.

    PubMed

    Lavoué, Sébastien; Miya, Masaki; Arnegard, Matthew E; Sullivan, John P; Hopkins, Carl D; Nishida, Mutsumi

    2012-01-01

    One of the most remarkable examples of convergent evolution among vertebrates is illustrated by the independent origins of an active electric sense in South American and African weakly electric fishes, the Gymnotiformes and Mormyroidea, respectively. These groups independently evolved similar complex systems for object localization and communication via the generation and reception of weak electric fields. While good estimates of divergence times are critical to understanding the temporal context for the evolution and diversification of these two groups, their respective ages have been difficult to estimate due to the absence of an informative fossil record, use of strict molecular clock models in previous studies, and/or incomplete taxonomic sampling. Here, we examine the timing of the origins of the Gymnotiformes and the Mormyroidea using complete mitogenome sequences and a parametric bayesian method for divergence time reconstruction. Under two different fossil-based calibration methods, we estimated similar ages for the independent origins of the Mormyroidea and Gymnotiformes. Our absolute estimates for the origins of these groups either slightly postdate, or just predate, the final separation of Africa and South America by continental drift. The most recent common ancestor of the Mormyroidea and Gymnotiformes was found to be a non-electrogenic basal teleost living more than 85 millions years earlier. For both electric fish lineages, we also estimated similar intervals (16-19 or 22-26 million years, depending on calibration method) between the appearance of electroreception and the origin of myogenic electric organs, providing rough upper estimates for the time periods during which these complex electric organs evolved de novo from skeletal muscle precursors. The fact that the Gymnotiformes and Mormyroidea are of similar age enhances the comparative value of the weakly electric fish system for investigating pathways to evolutionary novelty, as well as the

  11. Comparable Ages for the Independent Origins of Electrogenesis in African and South American Weakly Electric Fishes

    PubMed Central

    Lavoué, Sébastien; Miya, Masaki; Arnegard, Matthew E.; Sullivan, John P.; Hopkins, Carl D.; Nishida, Mutsumi

    2012-01-01

    One of the most remarkable examples of convergent evolution among vertebrates is illustrated by the independent origins of an active electric sense in South American and African weakly electric fishes, the Gymnotiformes and Mormyroidea, respectively. These groups independently evolved similar complex systems for object localization and communication via the generation and reception of weak electric fields. While good estimates of divergence times are critical to understanding the temporal context for the evolution and diversification of these two groups, their respective ages have been difficult to estimate due to the absence of an informative fossil record, use of strict molecular clock models in previous studies, and/or incomplete taxonomic sampling. Here, we examine the timing of the origins of the Gymnotiformes and the Mormyroidea using complete mitogenome sequences and a parametric Bayesian method for divergence time reconstruction. Under two different fossil-based calibration methods, we estimated similar ages for the independent origins of the Mormyroidea and Gymnotiformes. Our absolute estimates for the origins of these groups either slightly postdate, or just predate, the final separation of Africa and South America by continental drift. The most recent common ancestor of the Mormyroidea and Gymnotiformes was found to be a non-electrogenic basal teleost living more than 85 millions years earlier. For both electric fish lineages, we also estimated similar intervals (16–19 or 22–26 million years, depending on calibration method) between the appearance of electroreception and the origin of myogenic electric organs, providing rough upper estimates for the time periods during which these complex electric organs evolved de novo from skeletal muscle precursors. The fact that the Gymnotiformes and Mormyroidea are of similar age enhances the comparative value of the weakly electric fish system for investigating pathways to evolutionary novelty, as well as the

  12. Spectroscopic studies of the physical origin of environmental aging effects on doped graphene

    NASA Astrophysics Data System (ADS)

    Chang, J.-K.; Hsu, C.-C.; Liu, S.-Y.; Wu, C.-I.; Gharib, M.; Yeh, N.-C.

    2016-06-01

    The environmental aging effect of doped graphene is investigated as a function of the organic doping species, humidity, and the number of graphene layers adjacent to the dopant by studies of the Raman spectroscopy, x-ray and ultraviolet photoelectron spectroscopy, scanning electron microscopy, infrared spectroscopy, and electrical transport measurements. It is found that higher humidity and structural defects induce faster degradation in doped graphene. Detailed analysis of the spectroscopic data suggest that the physical origin of the aging effect is associated with the continuing reaction of H2O molecules with the hygroscopic organic dopants, which leads to formation of excess chemical bonds, reduction in the doped graphene carrier density, and proliferation of damages from the graphene grain boundaries. These environmental aging effects are further shown to be significantly mitigated by added graphene layers.

  13. 75 FR 32958 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-10

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Drug Effects on Illnesses in the Aging Population. Date: June 29, 2010. Time: 12 p.m. to 4 p.m. Agenda: To review and evaluate grant...

  14. 76 FR 55691 - National Institute on Aging Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-08

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Aminergic Function and Brain Aging II....

  15. 76 FR 28794 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-18

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Longevity Consortium. Date: June 9, 2011... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, (Telephone...

  16. 77 FR 21790 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Loan Repayment 2012. Date: May 2, 2012. Time... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892. Contact Person:...

  17. 78 FR 57167 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-17

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Disability and Employment. Date: October 17... Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda, MD 20892. Contact...

  18. 77 FR 2737 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Network Facilities for Developing Areas of Investigation in the Basic Biology of Aging. Date: February 9, 2012. Time: 8:30 a.m. to 9:30 a.m. Agenda:...

  19. 78 FR 36200 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-17

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Longitudinal Study Contract. Date: June 26... Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20814,...

  20. 75 FR 8374 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, New Invertebrate Models for the Biology of Aging. Date: March 18, 2010. Time: 8:30 a.m. to 3:30 p.m. Agenda: To review and evaluate...

  1. 77 FR 65005 - National Institute on Aging Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-24

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Juvenile Protective Factors. Date: December 4... Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892. Contact...

  2. 77 FR 21790 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Pathology of Alzheimer's Disease. Date: May 7... Institute on Aging, Gateway Building 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892,...

  3. 78 FR 9403 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-08

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; CALERIE Dataset. Date: March 7, 2013. Time: 1... Aging, Gateway Building, Room 2C212, 7201 Wisconsin Avenue, Bethesda, MD 20892, (Telephone...

  4. 75 FR 11188 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel, Nursing Home Research. Date: May 7, 2010... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892. (Telephone...

  5. 77 FR 56855 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Skeletal Muscle. ] Date: October 23, 2012... Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892...

  6. 78 FR 4423 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Worm Intervention Study. Date: February 20... Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda, MD 20892,...

  7. 77 FR 5030 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel Testosterone Studies. Date: February 16, 2012... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, (Telephone...

  8. 75 FR 3476 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Clinical Services. Date: January 29, 2010... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892. (Telephone...

  9. 76 FR 35901 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Signal Transduction. Date: July 12, 2011... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, (Telephone...

  10. 75 FR 39549 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-09

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; ARRA--MIND MRI. Date: July 26, 2010. Time: 1... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212. Bethesda, MD 20892. (Telephone...

  11. 78 FR 26793 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-08

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Asthma in Older Adults. Date: May 29, 2013... Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda, MD 20892...

  12. 76 FR 11798 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-03

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Member Conflict. Date: March 15, 2011. Time... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892 (Telephone...

  13. 78 FR 67177 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-08

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Member Conflict. Date: December 18, 2013... Institute of Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda, MD 20892,...

  14. 78 FR 75358 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Vitamin D Trials. Date: January 30, 2014... Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda, MD 20892...

  15. 78 FR 70310 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-25

    ... Committee: National Institute on Aging Special Emphasis Panel; Exercise and AD. Date: December 23, 2013... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda, MD 20892,...

  16. Origins.

    ERIC Educational Resources Information Center

    Online-Offline, 1999

    1999-01-01

    Provides an annotated list of resources dealing with the theme of origins of life, the universe, and traditions. Includes Web sites, videos, books, audio materials, and magazines with appropriate grade levels and/or subject disciplines indicated; professional resources; and learning activities. (LRW)

  17. 23 CFR 1208.4 - Adoption of National Minimum Drinking Age.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Adoption of National Minimum Drinking Age. 1208.4 Section 1208.4 Highways NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION AND FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GUIDELINES NATIONAL MINIMUM DRINKING AGE § 1208.4 Adoption of National...

  18. 23 CFR 1208.4 - Adoption of National Minimum Drinking Age.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Adoption of National Minimum Drinking Age. 1208.4 Section 1208.4 Highways NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION AND FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GUIDELINES NATIONAL MINIMUM DRINKING AGE § 1208.4 Adoption of National...

  19. 23 CFR 1208.4 - Adoption of National Minimum Drinking Age.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Adoption of National Minimum Drinking Age. 1208.4 Section 1208.4 Highways NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION AND FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GUIDELINES NATIONAL MINIMUM DRINKING AGE § 1208.4 Adoption of National...

  20. 23 CFR 1208.4 - Adoption of National Minimum Drinking Age.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Adoption of National Minimum Drinking Age. 1208.4 Section 1208.4 Highways NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION AND FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GUIDELINES NATIONAL MINIMUM DRINKING AGE § 1208.4 Adoption of National...

  1. 23 CFR 1208.4 - Adoption of National Minimum Drinking Age.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Adoption of National Minimum Drinking Age. 1208.4 Section 1208.4 Highways NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION AND FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GUIDELINES NATIONAL MINIMUM DRINKING AGE § 1208.4 Adoption of National...

  2. 76 FR 23827 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-28

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel Osteoarthritis. Date: June 8, 2011. Time: 9 a.m. to 1 p.m. Agenda: To review and evaluate grant applications. Place: National Institute on...

  3. 75 FR 18511 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-12

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel, Loan Repayment. Date: May 3, 2010. Time: 12 p.m. to 4 p.m. Agenda: To review and evaluate grant applications. Place: National Institute on...

  4. 78 FR 35041 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel SWAN. Date: June 27, 2013. Time: 9:30 a.m. to 12:30 p.m. Agenda: To review and evaluate grant applications. Place: National Institute on...

  5. 78 FR 16273 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-14

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel. Date: April 1, 2013. Time: 12:00 p.m. to 12:30 p.m. Agenda: To review and evaluate grant applications. Place: National Institute on...

  6. Molecular and Chemical Genetic Approaches to Developmental Origins of Aging and Disease in Zebrafish

    PubMed Central

    Sasaki, Tomoyuki; Kishi, Shuji

    2013-01-01

    The incidence of diseases increases rapidly with age, accompanied by progressive deteriorations of physiological functions in organisms. Aging-associated diseases are sporadic but mostly inevitable complications arising from senescence. Senescence is often considered the antithesis of early development, but yet there may be factors and mechanisms in common between these two phenomena over the dynamic process of aging. The association between early development and late-onset disease with advancing age is thought to come from a consequence of developmental plasticity, the phenomenon by which one genotype can give rise to a range of physiologically and/or morphologically adaptive states in response to different environmental or genetic perturbations. On the one hand, we hypothesized that the future aging process can be predictive based on adaptivity during the early developmental period. Modulating the thresholds of adaptive plasticity by chemical genetic approaches, we have been investigating whether any relationship exists between the regulatory mechanisms that function in early development and in senescence using the zebrafish (Danio rerio), a small freshwater fish and a useful model animal for genetic studies. We have successfully conducted experiments to isolate zebrafish mutants expressing apparently altered senescence phenotypes during embryogenesis (“embryonic senescence”), subsequently showing shortened lifespan in adulthoods. We anticipate that previously uncharacterized developmental genes may mediate the aging process and play a pivotal role in senescence. On the other hand, unexpected senescence-related genes might also be involved in the early developmental process and regulation. The ease of manipulation using the zebrafish system allows us to conduct an exhaustive exploration of novel genes and small molecular compounds that can be linked to the senescence phenotype, and thereby facilitates searching for the evolutionary and developmental origins

  7. The Zebrafish Models to Explore Genetic and Epigenetic Impacts on Evolutionary Developmental Origins of Aging

    PubMed Central

    Kishi, Shuji

    2014-01-01

    hand, unexpected senescence-related genes might also be involved in the early developmental process and its regulation. The ease of manipulation using the zebrafish system allows us to conduct an exhaustive exploration of novel genes/genotypes and epigenotype that can be linked to the senescence phenotype, and thereby facilitates searching for the evolutionary and developmental origins of aging in vertebrates. PMID:24239812

  8. Impact Constraints on the Age and Origin of the Crustal Dichotomy on Mars

    NASA Technical Reports Server (NTRS)

    Frey, Herbert V.

    2004-01-01

    MOLA data have revealed a large population of 'Quasi-Circular Depressions' (QCDs) with little or no visible expression in image data. These likely buried impact basins have important implications for the age of the lowland crust, how that compares with original highland crust, and when and how the crustal dichotomy may have formed. The buried lowlands are of Early Noachian age, likely slightly younger than the buried highlands but older than the exposed (visible) highland surface. A depopulation of large visible basins at diameters 800 to 1300 km suggests some global scale event early in martian history, maybe related to the formation of the lowlands and/or the development of Tharsis. A suggested early disappearance of the global magnetic field can be placed within a temporal sequence of formation of the very largest impact basins. The global field appears to have disappeared at about the time the lowlands formed. It seems likely the topographic crustal dichotomy was produced very early in martian history by processes which operated very quickly. This and the preservation of large relic impact basins in the northern hemisphere, which themselves can account for the lowland topography, suggest that large impacts played the major role in the origin Mars fundamental crustal feature.

  9. Ages, distributions, and origins of upland coastal dune sheets in Oregon, USA

    USGS Publications Warehouse

    Peterson, C.D.; Stock, E.; Price, D.M.; Hart, R.; Reckendorf, F.; Erlandson, J.M.; Hostetler, S.W.

    2007-01-01

    A total of ten upland dune sheets, totaling 245??km in combined length, have been investigated for their origin(s) along the Oregon coast (500??km in length). The ages of dune emplacement range from 0.1 to 103??ka based on radiocarbon (36 samples) and luminescence (46 samples) dating techniques. The majority of the emplacement dates fall into two periods of late-Pleistocene age (11-103??ka) and mid-late-Holocene age (0.1-8??ka) that correspond to marine low-stand and marine high-stand conditions, respectively. The distribution of both the late-Pleistocene dune sheets (516??km2 total surface area) and the late-Holocene dune sheets (184??km2) are concentrated (90% of total surface area) along a 100??km coastal reach of the south-central Oregon coast. This coastal reach lies directly landward of a major bight (Heceta-Perpetua-Stonewall Banks) on the continental shelf, at depths of 30-200??m below present mean sea level (MSL). The banks served to trap northward littoral drift during most of the late-Pleistocene conditions of lowered sea level (- 50 ?? 20??m MSL). The emerged inner-shelf permitted cross-shelf, eolian sand transport (10-50??km distance) by onshore winds. The depocenter sand deposits were reworked by the Holocene marine transgression and carried landward by asymmetric wave transport during early- to mid-Holocene time. The earliest dated onset of Holocene dune accretion occurred at 8??ka in the central Oregon coast. A northward migration of Northeast Pacific storm tracks to the latitude of the shelf depocenter (Stonewall, Perpetua, Heceta Banks) in Holocene time resulted in eastward wave transport from the offshore depocenter. The complex interplay of coastal morphology, paleosea-level, and paleoclimate yielded the observed peak distribution of beach and dune sand observed along the south-central Oregon coast. ?? 2007 Elsevier B.V. All rights reserved.

  10. 75 FR 28031 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-19

    ... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant...: Jeannette L. Johnson, PhD, Scientific Review Officer, National Institutes On Aging, National Institutes of..., PhD, Scientific Review Officer, Scientific Review Branch, National Institute On Aging, Gateway...

  11. 76 FR 48873 - National Institute on Aging Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, AD Mutation. Date: August 30, 2011. Time: 1...

  12. 78 FR 37232 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings...: National Institute on Aging Special Emphasis Panel; Treatment of Obesity in Older Adults. Date: July...

  13. 76 FR 60058 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Reproductive Hormones and the Brain II....

  14. 78 FR 66373 - National Institute on Aging; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-05

    ... Federal Register on September 25, 2013, 59042- 59043 FR 186. Meeting will be held December 12, 2013 from... HUMAN SERVICES National Institutes of Health National Institute on Aging; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Institute on Aging Special...

  15. 78 FR 66368 - National Institute on Aging; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-05

    ... Federal Register on September 17, 2013, 78 FR 57167. Meeting will be held on November 26, 2013 from 1:00 p... HUMAN SERVICES National Institutes of Health National Institute on Aging; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Institute on Aging Special...

  16. 78 FR 66369 - National Institute on Aging; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-05

    ... Federal Register on September 17, 2013, 57167 FR 180. Meeting will be held on December 19, 2013 from 12:00... HUMAN SERVICES National Institutes of Health National Institute on Aging; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Institute on Aging Special...

  17. Lunar crater arcs. [origins, distribution and age classification of Pre-Imbrian families

    NASA Technical Reports Server (NTRS)

    Jaffe, L. D.; Bulkley, E. O.

    1976-01-01

    An analysis has been made of the tendency of large lunar craters to lie along circles. A catalog of the craters at least 50 km in diameter was prepared first, noting position, diameter, rim sharpness and completion, nature of underlying surface, and geological age. The subset of those craters 50-400 km in diameter was then used as input to computer programs which identified each 'family' of four or more craters of selected geological age lying on a circular arc. For comparison, families were also identified for randomized crater models in which the crater spatial density was matched to that on the moon, either overall or separately for mare and highland areas. The observed frequency of lunar arcuate families was statistically highly significantly greater than for the randomized models, for craters classified as either late-pre-Imbrian (Nectarian), middle pre-Imbrian, or early pre-Imbrian, as well as for a number of larger age-classes. The lunar families tend to center in specific areas of the moon; these lie in highlands rather than maria and are different for families of Nectarian craters than for pre-Nectarian. The origin of the arcuate crater groupings is not understood.

  18. Snow-avalanche impact landforms in Breheimen, southern Norway: Origin, age, and paleoclimatic implications

    SciTech Connect

    Matthews, J.A.; McCarroll, D. )

    1994-05-01

    Twelve snow-avalanche ramparts in Jostedalen and Sprongdalen (Breheimen, southern Norway) are investigated to elucidate processes of formation, the history of avalanche activity, and their potential for paleoclimatic reconstruction. Variation in the form of these riverbank boulder ramparts reflects local patterns of avalanche impact. Differences in clast roundness between ramparts, avalanche tracks, and river beds indicate that, on average, 50 to 60% of the clasts in the ramparts originate from river bedload as opposed to avalanche source areas or tracks. Rampart clasts increase in roundness downstream over a distance of 12 km, and the contribution from the river bed varies from 26 to 80% depending on local factors. Conventional lichenometric dating suggests ages for the initiation of rampart formation of 250 to 2000 yr, but they probably have a much longer history. Lichen-size frequency distributions, using the largest lichen from each of n boulders, reflect the age-frequency of surface boulders, providing a record of late Holocene avalanche activity. A simulation model suggests that maximum avalanche activity affected nine of the ramparts during the 19th century, after the peak of the Little Ice Age. The pattern of avalanche activity differs from the pattern of glacier variations but is in close agreement with that of debris-flow activity. The ramparts may yield a valuable proxy record of winter snowfall. 48 refs., 12 figs., 4 tabs.

  19. Investigating age and origin of ice-cored moraines in Jotunheimen and Breheimen/Southern Norway

    NASA Astrophysics Data System (ADS)

    Winkler, Stefan; Matthews, John; Wilson, Peter

    2015-04-01

    Ice-cored moraines characteristic for the high-alpine zones in the Jotunheimen and Breheimen mountain regions of southern Norway have been recognised, described, and studied as early as during the 1950s and 1960s. These complex multiple-ridged, ramp-like moraines of up to 50 m in height occurring at comparatively small but high-lying glaciers differ considerably from those typical for the other glaciers at lower altitudes. The existence of their ice-core beneath rather thin debris cover and a spatial concentration in the north-eastern part of the regions with a higher snow line and stronger climatic continentality points towards their link with alpine permafrost. Until today, there is no consensus about either the mechanisms of their formation or their age constraints. Based on few (possibly less reliable) radiocarbon ages retrieved from dust within the ice cores the innermost (proximal) ridges were, for example, interpreted as rather old and the outermost ridges as youngest. Consequently, the innermost ridges need to have survived successive overriding during more extensive glacier advances. Alternatively, these ice-cored moraines have also been interpreted as initial rock glaciers and the younger ages of the outer ridges explained by 'pressing-out' of material from the base of the moraine by its own weight and gravity. Other theories developed include also a mixture of traditional push moraine processes and deformation structures caused by the glacier advancing in a permafrost environment ('push-deformation moraine'). Because reliable age constraints for individual ridges of those complex ice-cored moraine complexes are crucial for any interpretation of their mode of formation, this study aims to provide insights into their age and origin by applying high-precision Schmidt-hammer exposure-age dating (SHD). Local SHD calibration curves using moraine ridges dating from the last 50 years to the Preboreal (c. 9700 years ago) have been used to give age estimates for

  20. Ages and Origins of Calcite and Opal in the Exploratory Studies Facility Tunnel, Yucca Mountain, Nevada

    USGS Publications Warehouse

    Paces, James B.; Neymark, Leonid A.; Marshall, Brian D.; Whelan, Joseph F.; Peterman, Zell E.

    2001-01-01

    and smallest delta oxygen-18 values compared to calcite from intermediate and outer positions. Basal calcite has relatively small strontium-87/strontium-86 ratios, between 0.7105 and 0.7120, that are similar to the initial isotopic compositions of the strontium-rich tuff units, whereas outer calcite has more radiogenic strontium-87/strontium-86 ratios between 0.7115 and 0.7127. Isotopic compositions of strontium, oxygen, and carbon in the outer (youngest) unsaturated-zone calcite are coincident with those measured in Yucca Mountain calcrete, which formed by pedogenic processes. The physical and isotopic data from calcite and opal indicate that they formed from solutions of meteoric origin percolating through a limited network of connected fracture pathways in the unsaturated zone rather than by inundation from ascending ground water originating in the saturated zone. Mineral assemblages, textures, and distributions within the unsaturated zone are distinctly different from those deposited below the water table at Yucca Mountain. The calcite and opal typically are present only on footwall surfaces of a small fraction of fractures and only on floors of a small fraction of lithophysal cavities. The similarities in the carbon, oxygen, and strontium isotopic compositions between fracture calcite and soil-zone calcite, as well as the gradation of textures from detritus-rich micrite in the soil to detritus-free spar 10 to 30 meters below the surface, also support a genetic link between the two depositional environments. Older deposits contain oxygen isotope compositions that indicate elevated temperatures of mineral formation during the early stages of deposition; however, in the youngest deposits these values are consistent with deposition under geothermal gradients similar to modern conditions. Correlations between mineral ages and varying Pleistocene climate conditions are not apparent from the current data. Cumulative evidence from calcite and opal deposits indicate

  1. Subduction Along the South Caribbean Deformed Belt: Age of Initiation and Backthrust Origin

    NASA Astrophysics Data System (ADS)

    Mann, P.; Kroehler, M.; Escalona, A.; Magnani, B.; Christeson, G.

    2007-12-01

    The South Caribbean deformed belt (SCDB) represents a submarine prism formed at the interface between subducting oceanic material in the Colombian and Venezuelan basins and arc terranes along the northern edge of the South American continent. The SCDB and subducted Caribbean slab extends 1500 km from Panama to the Aves Ridge and is similar in scale to better studied magmatic subduction zones in the Lesser Antilles and Central America. The age of subduction of the Venezuelan basin at the SCDB has been examined by dating asymmetrical sediment wedges inferred to have formed above the bending and subducting slab of the Venezuelan basin. Ages are constrained by ties to DSDP wells drilled in the Venezuelan basin ~150 km north of the SCDB. Onlapping wedges are oldest in the western area near the Beata Ridge (middle Eocene), of intermediate age in the central area (early Miocene), and youngest in the east near the Aves Ridge (Mio- Pleistocene). Overlying younger wedges in all areas demonstrate that subduction continued following its initiation. Similar ages of deformed syn-thurst wedges are known from the now inactive continental foreland of northern South America in a belt from western Venezuela to Trinidad. Based on this correlation, we propose a simple back arc thrusting origin for the SCDB that is analogous to the eastern Sunda arc of Indonesia. The obliquity of convergence in the Caribbean case has produced a longlived, eastwardly-migrating backthrust that contrasts to more static backthrust in Sunda. The immediate onset of backthrusting following continental collision means that South America-Caribbean convergence was accommodated by newly organized and focussed subduction at the SCDB backthrust; the "collided" crust of intervening accreted arc terranes remains remarkably unaffected by regional shortening effects.

  2. Initial insights into the age and origin of the Kubuqi sand sea of northern China

    NASA Astrophysics Data System (ADS)

    Yang, Xiaoping; Forman, Steven; Hu, Fangen; Zhang, Deguo; Liu, Ziting; Li, Hongwei

    2016-04-01

    The Kubuqi Desert is the only active sand sea in the semiarid regions of northern China and occurs along the southern margin of the Yellow River. Little is known about the age and origin of this large (17,000 km2) sand sea with a present annual precipitation of 200-480 mm. Sand drift potentials indicated net capable winds for aeolian transport are from the northwest, though winds are stronger to north beyond the dune field than within the sand sea. Geomorphic and stratigraphic observations indicate that Holocene aeolian sand often drapes over bedrock and river terraces as a palimpsest landscape. Field investigations identified four stratigraphic sections with multiple aeolian sand units and palaeosols, with age control by optically stimulated luminescence (OSL) dating of quartz grains. Palaeosols are weakly developed, mostly accumulative A horizon with organic carbon content < 1% and reflect sand sheet deposition possibly in a steppe environment. Although sediments near river channels or former lakes might give old ages, the initial formation and age of the Kubuqi sand sea should be judged from the occurrence of the sandy palimpsest of the landscape that is OSL dated to the Holocene in general. The latest period of aeolian reactivation may be related to human activity associated with grazing and farming from lost cities in the Kubuqi Desert during the Han (206 B.C. - A.D. 220) and the Tang (A.D. 608 - 907) Dynasties. Also, variable discharge of the Yellow River with local diversions for irrigation and throughout the catchment resulted in possibly an increased supply of aeolian particles for dune field expansion in the past 2 ka.

  3. Age and origin of two common MLH1 mutations predisposing to hereditary colon cancer.

    PubMed Central

    Moisio, A. L.; Sistonen, P.; Weissenbach, J.; de la Chapelle, A.; Peltomäki, P.

    1996-01-01

    Two mutations in the DNA mismatch repair gene MLH1, referred to as mutations 1 and 2, are frequent among Finnish kindreds with hereditary nonpolyposis colorectal cancer (HNPCC). In order to assess the ages and origins of these mutations, we constructed a map of 15 microsatellite markers around MLH1 and used this information in haplotype analyses of 19 kindreds with mutation 1 and 6 kindreds with mutation 2. All kindreds with mutation 1 showed a single allele for the intragenic marker D3S1611 that was not observed on any unaffected chromosome. They also shared portions of a haplotype of 4-15 markers encompassing 2.0-19.0 cM around MLH1. All kindreds with mutation 2 shared another allele for D3S1611 and a conserved haplotype of 5-14 markers spanning 2.0-15.0 cM around MLH1. The degree of haplotype conservation was used to estimate the ages of these two mutations. While some recessive disease genes have been estimated to have existed and spread for as long as thousands of generations worldwide and hundreds of generations in the Finnish population, our analyses suggest that the spread of mutation 1 started 16-43 generations (400-1,075 years) ago and that of mutation 2 some 5-21 generations (125-525 years) ago. These datings are compatible with our genealogical results identifying a common ancestor born in the 16th and 18th century, respectively. Overall, our results indicate that all Finnish kindreds studied to date showing either mutation 1 or mutation 2 are due to single ancestral founding mutations relatively recent in origin in the population. Alternatively, the mutations arose elsewhere earlier and were introduced in Finland more recently. PMID:8940269

  4. Biological affinities and adaptations of Bronze Age Bactrians: IV. A craniometric investigation of Bactrian origins.

    PubMed

    Hemphill, B E

    1999-02-01

    Discovery of a previously unknown Bronze Age civilization (Oxus civilization) centered on the oases of Central Asia revealed the presence of large, preplanned urban centers immediately above sterile soil. Given the absence of local antecedents, the sudden appearance and proliferation of these Oxus civilization urban centers in the oases of Bactria and Margiana immediately raised the issue of where the inhabitants of these urban centers came from. Three hypotheses have been offered by archaeologists to account for the origins of Oxus civilization populations. These include the early influence model, the late colonization model, and the trichotomy model. Eleven craniometric variables from 12 Aeneolithic and Bronze Age samples, encompassing 657 adults from Central Asia, Iran, and the Indus Valley, are compared to test which if any of these hypotheses are supported by the pattern of phenetic affinities possessed by the Oxus civilization inhabitants of the north Bactrian oasis. Craniometric differences between samples are compared with Mahalanobis generalized distance (d2), and patterns of phenetic affinity are assessed with two types of cluster analysis (WPGMA, neighbor-joining method), multidimensional scaling, and principal coordinates analysis. Results of this analysis provide no support for either the late colonization model or the trichotomy model but do offer some support for the early influence model. Nevertheless, it is clear that the early influence model fails to account for a shift in interregional contacts, perhaps from western China to the north around 2000 BC, that appears to have played a major role in the origins of the Oxus civilization inhabitants of the north Bactrian oasis. PMID:9988380

  5. Teen-Age Pregnancy: The Case for National Action.

    ERIC Educational Resources Information Center

    Wattleton, Faye

    1989-01-01

    Reviews the national impact of adolescent pregnancy with emphasis on the Black community. Criticizes the mass media for exploiting sexual behavior. Proposes a national agenda incorporating comprehensive sex education, family planning services, and educational, economic, and social opportunities. (FMW)

  6. The origin and age of haplochromine fishes in Lake Victoria, east Africa.

    PubMed

    Nagl, S; Tichy, H; Mayer, W E; Takezaki, N; Takahata, N; Klein, J

    2000-05-22

    According to a widely held view, the more than 300 species of haplochromine cichlid fishes in Lake Victoria (LV), East Africa, originated from a single founder species in less than 12,000 years. This view, however, does not follow from the published geological and molecular evidence. The former does indeed suggest that the LV basin dried out less than 15,000 years ago, but it does not provide any information about the species that re-colonized the new lake or that remained in the rivers draining the area. The molecular evidence is inconclusive with respect to the origin of the LV haplochromines because cichlids from critical regions around LV were not adequately sampled; and as far as the age of the LV haplochromines is concerned, it in fact led to an estimate of 250,000-750,000 years old. In the present study, mitochondrial DNA (control region) variation was determined by heteroduplex and sequencing analyses of more than 670 specimens collected at widely distributed East African riverine and lacustrine localities. The analyses revealed the existence of seven haplogroups (I-VII) distinguishable by characteristic substitutions. All endemic LV samples tested fell into one of these haplogroups (V) which, however, was also found to be present at various other localities, both riverine and lacustrine, outside LV. Within this haplogroup, four subgroups (VA through VD) could be distinguished, two of which (VB and VC) were represented in LV and at other localities. The great majority of the LV haplochromine species could be classified as belonging to the VC subgroup, which was found only in LV and in the rivers draining into it. Hence, while the endemic haplochromine species of LV could not have originated from a single founding population, the lake does harbour a large species flock which probably arose in situ. PMID:10874756

  7. The origin and age of haplochromine fishes in Lake Victoria, east Africa.

    PubMed Central

    Nagl, S; Tichy, H; Mayer, W E; Takezaki, N; Takahata, N; Klein, J

    2000-01-01

    According to a widely held view, the more than 300 species of haplochromine cichlid fishes in Lake Victoria (LV), East Africa, originated from a single founder species in less than 12,000 years. This view, however, does not follow from the published geological and molecular evidence. The former does indeed suggest that the LV basin dried out less than 15,000 years ago, but it does not provide any information about the species that re-colonized the new lake or that remained in the rivers draining the area. The molecular evidence is inconclusive with respect to the origin of the LV haplochromines because cichlids from critical regions around LV were not adequately sampled; and as far as the age of the LV haplochromines is concerned, it in fact led to an estimate of 250,000-750,000 years old. In the present study, mitochondrial DNA (control region) variation was determined by heteroduplex and sequencing analyses of more than 670 specimens collected at widely distributed East African riverine and lacustrine localities. The analyses revealed the existence of seven haplogroups (I-VII) distinguishable by characteristic substitutions. All endemic LV samples tested fell into one of these haplogroups (V) which, however, was also found to be present at various other localities, both riverine and lacustrine, outside LV. Within this haplogroup, four subgroups (VA through VD) could be distinguished, two of which (VB and VC) were represented in LV and at other localities. The great majority of the LV haplochromine species could be classified as belonging to the VC subgroup, which was found only in LV and in the rivers draining into it. Hence, while the endemic haplochromine species of LV could not have originated from a single founding population, the lake does harbour a large species flock which probably arose in situ. PMID:10874756

  8. Age Differences in Personality: Evidence from a Nationally Representative Australian Sample

    ERIC Educational Resources Information Center

    Lucas, Richard E.; Donnellan, M. Brent

    2009-01-01

    Cross-sectional age differences in the Big Five personality traits were examined in a nationally representative sample of Australians (N = 12,618; age range = 15-84). Extraversion, Neuroticism, and Openness were negatively associated with age, whereas Agreeableness and Conscientiousness were positively associated with age. Effect sizes comparing…

  9. 41 CFR 102-36.445 - Do we report excess personal property originally acquired from or through the American National...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... personal property originally acquired from or through the American National Red Cross? 102-36.445 Section... Personal Property Whose Disposal Requires Special Handling Red Cross Property § 102-36.445 Do we report excess personal property originally acquired from or through the American National Red Cross? Yes,...

  10. 42 CFR 21.52 - Waiver of entrance qualifications for original appointment in time of war or national emergency.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Waiver of entrance qualifications for original appointment in time of war or national emergency. 21.52 Section 21.52 Public Health PUBLIC HEALTH SERVICE... entrance qualifications for original appointment in time of war or national emergency. If, in time of...

  11. 42 CFR 21.52 - Waiver of entrance qualifications for original appointment in time of war or national emergency.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Waiver of entrance qualifications for original appointment in time of war or national emergency. 21.52 Section 21.52 Public Health PUBLIC HEALTH SERVICE... entrance qualifications for original appointment in time of war or national emergency. If, in time of...

  12. 42 CFR 21.52 - Waiver of entrance qualifications for original appointment in time of war or national emergency.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Waiver of entrance qualifications for original appointment in time of war or national emergency. 21.52 Section 21.52 Public Health PUBLIC HEALTH SERVICE... entrance qualifications for original appointment in time of war or national emergency. If, in time of...

  13. 42 CFR 21.52 - Waiver of entrance qualifications for original appointment in time of war or national emergency.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Waiver of entrance qualifications for original appointment in time of war or national emergency. 21.52 Section 21.52 Public Health PUBLIC HEALTH SERVICE... entrance qualifications for original appointment in time of war or national emergency. If, in time of...

  14. 42 CFR 21.52 - Waiver of entrance qualifications for original appointment in time of war or national emergency.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Waiver of entrance qualifications for original appointment in time of war or national emergency. 21.52 Section 21.52 Public Health PUBLIC HEALTH SERVICE... entrance qualifications for original appointment in time of war or national emergency. If, in time of...

  15. 41 CFR 102-36.445 - Do we report excess personal property originally acquired from or through the American National...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... personal property originally acquired from or through the American National Red Cross? 102-36.445 Section... Personal Property Whose Disposal Requires Special Handling Red Cross Property § 102-36.445 Do we report excess personal property originally acquired from or through the American National Red Cross? Yes,...

  16. 41 CFR 102-36.445 - Do we report excess personal property originally acquired from or through the American National...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... personal property originally acquired from or through the American National Red Cross? 102-36.445 Section... Personal Property Whose Disposal Requires Special Handling Red Cross Property § 102-36.445 Do we report excess personal property originally acquired from or through the American National Red Cross? Yes,...

  17. 41 CFR 102-36.445 - Do we report excess personal property originally acquired from or through the American National...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... personal property originally acquired from or through the American National Red Cross? 102-36.445 Section... Personal Property Whose Disposal Requires Special Handling Red Cross Property § 102-36.445 Do we report excess personal property originally acquired from or through the American National Red Cross? Yes,...

  18. 41 CFR 102-36.445 - Do we report excess personal property originally acquired from or through the American National...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... personal property originally acquired from or through the American National Red Cross? 102-36.445 Section... Personal Property Whose Disposal Requires Special Handling Red Cross Property § 102-36.445 Do we report excess personal property originally acquired from or through the American National Red Cross? Yes,...

  19. 13 CFR 113.3-1 - Consideration of race, color, religion, sex, marital status, handicap, or national origin.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., religion, sex, marital status, handicap, or national origin. 113.3-1 Section 113.3-1 Business Credit and... of race, color, religion, sex, marital status, handicap, or national origin. (a) This regulation does not prohibit the consideration of race, color, religion, sex, marital status, handicap, or...

  20. 13 CFR 113.3-1 - Consideration of race, color, religion, sex, marital status, handicap, or national origin.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., religion, sex, marital status, handicap, or national origin. 113.3-1 Section 113.3-1 Business Credit and... of race, color, religion, sex, marital status, handicap, or national origin. (a) This regulation does not prohibit the consideration of race, color, religion, sex, marital status, handicap, or...

  1. 13 CFR 113.3-1 - Consideration of race, color, religion, sex, marital status, handicap, or national origin.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., religion, sex, marital status, handicap, or national origin. 113.3-1 Section 113.3-1 Business Credit and... of race, color, religion, sex, marital status, handicap, or national origin. (a) This regulation does not prohibit the consideration of race, color, religion, sex, marital status, handicap, or...

  2. 13 CFR 113.3-1 - Consideration of race, color, religion, sex, marital status, handicap, or national origin.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., religion, sex, marital status, handicap, or national origin. 113.3-1 Section 113.3-1 Business Credit and... of race, color, religion, sex, marital status, handicap, or national origin. (a) This regulation does not prohibit the consideration of race, color, religion, sex, marital status, handicap, or...

  3. 13 CFR 113.3-1 - Consideration of race, color, religion, sex, marital status, handicap, or national origin.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., religion, sex, marital status, handicap, or national origin. 113.3-1 Section 113.3-1 Business Credit and... of race, color, religion, sex, marital status, handicap, or national origin. (a) This regulation does not prohibit the consideration of race, color, religion, sex, marital status, handicap, or...

  4. Behavioral Autonomy Age Expectations among Mexican-Origin Mother-Daughter Dyads: An Examination of Within-Group Variability

    ERIC Educational Resources Information Center

    Bamaca-Colbert, Mayra Y.; Umana-Taylor, Adriana J.; Espinosa-Hernandez, Graciela; Brown, Ashley M.

    2012-01-01

    This study examined differences in behavioral autonomy age expectations between Mexican-origin mothers and their adolescent daughters (N = 319 dyads); variability in behavioral autonomy age expectations as a function of nativity and maternal educational attainment also was examined. Findings indicated significant differences between mothers and…

  5. Parent-of-origin specific allelic associations among 106 genomic loci for age at menarche

    PubMed Central

    Thompson, Deborah J; Ferreira, Teresa; He, Chunyan; Chasman, Daniel I; Esko, Tõnu; Thorleifsson, Gudmar; Albrecht, Eva; Ang, Wei Q; Corre, Tanguy; Cousminer, Diana L; Feenstra, Bjarke; Franceschini, Nora; Ganna, Andrea; Johnson, Andrew D; Kjellqvist, Sanela; Lunetta, Kathryn L; McMahon, George; Nolte, Ilja M; Paternoster, Lavinia; Porcu, Eleonora; Smith, Albert V; Stolk, Lisette; Teumer, Alexander; Tšernikova, Natalia; Tikkanen, Emmi; Ulivi, Sheila; Wagner, Erin K; Amin, Najaf; Bierut, Laura J; Byrne, Enda M; Hottenga, Jouke-Jan; Koller, Daniel L; Mangino, Massimo; Pers, Tune H; Yerges-Armstrong, Laura M; Zhao, Jing Hua; Andrulis, Irene L; Anton-Culver, Hoda; Atsma, Femke; Bandinelli, Stefania; Beckmann, Matthias W; Benitez, Javier; Blomqvist, Carl; Bojesen, Stig E; Bolla, Manjeet K; Bonanni, Bernardo; Brauch, Hiltrud; Brenner, Hermann; Buring, Julie E; Chang-Claude, Jenny; Chanock, Stephen; Chen, Jinhui; Chenevix-Trench, Georgia; Collée, J. Margriet; Couch, Fergus J; Couper, David; Coveillo, Andrea D; Cox, Angela; Czene, Kamila; D’adamo, Adamo Pio; Smith, George Davey; De Vivo, Immaculata; Demerath, Ellen W; Dennis, Joe; Devilee, Peter; Dieffenbach, Aida K; Dunning, Alison M; Eiriksdottir, Gudny; Eriksson, Johan G; Fasching, Peter A; Ferrucci, Luigi; Flesch-Janys, Dieter; Flyger, Henrik; Foroud, Tatiana; Franke, Lude; Garcia, Melissa E; García-Closas, Montserrat; Geller, Frank; de Geus, Eco EJ; Giles, Graham G; Gudbjartsson, Daniel F; Gudnason, Vilmundur; Guénel, Pascal; Guo, Suiqun; Hall, Per; Hamann, Ute; Haring, Robin; Hartman, Catharina A; Heath, Andrew C; Hofman, Albert; Hooning, Maartje J; Hopper, John L; Hu, Frank B; Hunter, David J; Karasik, David; Kiel, Douglas P; Knight, Julia A; Kosma, Veli-Matti; Kutalik, Zoltan; Lai, Sandra; Lambrechts, Diether; Lindblom, Annika; Mägi, Reedik; Magnusson, Patrik K; Mannermaa, Arto; Martin, Nicholas G; Masson, Gisli; McArdle, Patrick F; McArdle, Wendy L; Melbye, Mads; Michailidou, Kyriaki; Mihailov, Evelin; Milani, Lili; Milne, Roger L; Nevanlinna, Heli; Neven, Patrick; Nohr, Ellen A; Oldehinkel, Albertine J; Oostra, Ben A; Palotie, Aarno; Peacock, Munro; Pedersen, Nancy L; Peterlongo, Paolo; Peto, Julian; Pharoah, Paul DP; Postma, Dirkje S; Pouta, Anneli; Pylkäs, Katri; Radice, Paolo; Ring, Susan; Rivadeneira, Fernando; Robino, Antonietta; Rose, Lynda M; Rudolph, Anja; Salomaa, Veikko; Sanna, Serena; Schlessinger, David; Schmidt, Marjanka K; Southey, Mellissa C; Sovio, Ulla; Stampfer, Meir J; Stöckl, Doris; Storniolo, Anna M; Timpson, Nicholas J; Tyrer, Jonathan; Visser, Jenny A; Vollenweider, Peter; Völzke, Henry; Waeber, Gerard; Waldenberger, Melanie; Wallaschofski, Henri; Wang, Qin; Willemsen, Gonneke; Winqvist, Robert; Wolffenbuttel, Bruce HR; Wright, Margaret J; Boomsma, Dorret I; Econs, Michael J; Khaw, Kay-Tee; Loos, Ruth JF; McCarthy, Mark I; Montgomery, Grant W; Rice, John P; Streeten, Elizabeth A; Thorsteinsdottir, Unnur; van Duijn, Cornelia M; Alizadeh, Behrooz Z; Bergmann, Sven; Boerwinkle, Eric; Boyd, Heather A; Crisponi, Laura; Gasparini, Paolo; Gieger, Christian; Harris, Tamara B; Ingelsson, Erik; Järvelin, Marjo-Riitta; Kraft, Peter; Lawlor, Debbie; Metspalu, Andres; Pennell, Craig E; Ridker, Paul M; Snieder, Harold; Sørensen, Thorkild IA; Spector, Tim D; Strachan, David P; Uitterlinden, André G; Wareham, Nicholas J; Widen, Elisabeth; Zygmunt, Marek; Murray, Anna; Easton, Douglas F

    2014-01-01

    Age at menarche is a marker of timing of puberty in females. It varies widely between individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes, cardiovascular disease, breast cancer and all-cause mortality1. Studies of rare human disorders of puberty and animal models point to a complex hypothalamic-pituitary-hormonal regulation2,3, but the mechanisms that determine pubertal timing and underlie its links to disease risk remain unclear. Here, using genome-wide and custom-genotyping arrays in up to 182,416 women of European descent from 57 studies, we found robust evidence (P<5×10−8) for 123 signals at 106 genomic loci associated with age at menarche. Many loci were associated with other pubertal traits in both sexes, and there was substantial overlap with genes implicated in body mass index and various diseases, including rare disorders of puberty. Menarche signals were enriched in imprinted regions, with three loci (DLK1/WDR25, MKRN3/MAGEL2 and KCNK9) demonstrating parent-of-origin specific associations concordant with known parental expression patterns. Pathway analyses implicated nuclear hormone receptors, particularly retinoic acid and gamma-aminobutyric acid-B2 receptor signaling, among novel mechanisms that regulate pubertal timing in humans. Our findings suggest a genetic architecture involving at least hundreds of common variants in the coordinated timing of the pubertal transition. PMID:25231870

  6. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.

    PubMed

    Perry, John R B; Day, Felix; Elks, Cathy E; Sulem, Patrick; Thompson, Deborah J; Ferreira, Teresa; He, Chunyan; Chasman, Daniel I; Esko, Tõnu; Thorleifsson, Gudmar; Albrecht, Eva; Ang, Wei Q; Corre, Tanguy; Cousminer, Diana L; Feenstra, Bjarke; Franceschini, Nora; Ganna, Andrea; Johnson, Andrew D; Kjellqvist, Sanela; Lunetta, Kathryn L; McMahon, George; Nolte, Ilja M; Paternoster, Lavinia; Porcu, Eleonora; Smith, Albert V; Stolk, Lisette; Teumer, Alexander; Tšernikova, Natalia; Tikkanen, Emmi; Ulivi, Sheila; Wagner, Erin K; Amin, Najaf; Bierut, Laura J; Byrne, Enda M; Hottenga, Jouke-Jan; Koller, Daniel L; Mangino, Massimo; Pers, Tune H; Yerges-Armstrong, Laura M; Hua Zhao, Jing; Andrulis, Irene L; Anton-Culver, Hoda; Atsma, Femke; Bandinelli, Stefania; Beckmann, Matthias W; Benitez, Javier; Blomqvist, Carl; Bojesen, Stig E; Bolla, Manjeet K; Bonanni, Bernardo; Brauch, Hiltrud; Brenner, Hermann; Buring, Julie E; Chang-Claude, Jenny; Chanock, Stephen; Chen, Jinhui; Chenevix-Trench, Georgia; Collée, J Margriet; Couch, Fergus J; Couper, David; Coviello, Andrea D; Cox, Angela; Czene, Kamila; D'adamo, Adamo Pio; Davey Smith, George; De Vivo, Immaculata; Demerath, Ellen W; Dennis, Joe; Devilee, Peter; Dieffenbach, Aida K; Dunning, Alison M; Eiriksdottir, Gudny; Eriksson, Johan G; Fasching, Peter A; Ferrucci, Luigi; Flesch-Janys, Dieter; Flyger, Henrik; Foroud, Tatiana; Franke, Lude; Garcia, Melissa E; García-Closas, Montserrat; Geller, Frank; de Geus, Eco E J; Giles, Graham G; Gudbjartsson, Daniel F; Gudnason, Vilmundur; Guénel, Pascal; Guo, Suiqun; Hall, Per; Hamann, Ute; Haring, Robin; Hartman, Catharina A; Heath, Andrew C; Hofman, Albert; Hooning, Maartje J; Hopper, John L; Hu, Frank B; Hunter, David J; Karasik, David; Kiel, Douglas P; Knight, Julia A; Kosma, Veli-Matti; Kutalik, Zoltan; Lai, Sandra; Lambrechts, Diether; Lindblom, Annika; Mägi, Reedik; Magnusson, Patrik K; Mannermaa, Arto; Martin, Nicholas G; Masson, Gisli; McArdle, Patrick F; McArdle, Wendy L; Melbye, Mads; Michailidou, Kyriaki; Mihailov, Evelin; Milani, Lili; Milne, Roger L; Nevanlinna, Heli; Neven, Patrick; Nohr, Ellen A; Oldehinkel, Albertine J; Oostra, Ben A; Palotie, Aarno; Peacock, Munro; Pedersen, Nancy L; Peterlongo, Paolo; Peto, Julian; Pharoah, Paul D P; Postma, Dirkje S; Pouta, Anneli; Pylkäs, Katri; Radice, Paolo; Ring, Susan; Rivadeneira, Fernando; Robino, Antonietta; Rose, Lynda M; Rudolph, Anja; Salomaa, Veikko; Sanna, Serena; Schlessinger, David; Schmidt, Marjanka K; Southey, Mellissa C; Sovio, Ulla; Stampfer, Meir J; Stöckl, Doris; Storniolo, Anna M; Timpson, Nicholas J; Tyrer, Jonathan; Visser, Jenny A; Vollenweider, Peter; Völzke, Henry; Waeber, Gerard; Waldenberger, Melanie; Wallaschofski, Henri; Wang, Qin; Willemsen, Gonneke; Winqvist, Robert; Wolffenbuttel, Bruce H R; Wright, Margaret J; Boomsma, Dorret I; Econs, Michael J; Khaw, Kay-Tee; Loos, Ruth J F; McCarthy, Mark I; Montgomery, Grant W; Rice, John P; Streeten, Elizabeth A; Thorsteinsdottir, Unnur; van Duijn, Cornelia M; Alizadeh, Behrooz Z; Bergmann, Sven; Boerwinkle, Eric; Boyd, Heather A; Crisponi, Laura; Gasparini, Paolo; Gieger, Christian; Harris, Tamara B; Ingelsson, Erik; Järvelin, Marjo-Riitta; Kraft, Peter; Lawlor, Debbie; Metspalu, Andres; Pennell, Craig E; Ridker, Paul M; Snieder, Harold; Sørensen, Thorkild I A; Spector, Tim D; Strachan, David P; Uitterlinden, André G; Wareham, Nicholas J; Widen, Elisabeth; Zygmunt, Marek; Murray, Anna; Easton, Douglas F; Stefansson, Kari; Murabito, Joanne M; Ong, Ken K

    2014-10-01

    Age at menarche is a marker of timing of puberty in females. It varies widely between individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes, cardiovascular disease, breast cancer and all-cause mortality. Studies of rare human disorders of puberty and animal models point to a complex hypothalamic-pituitary-hormonal regulation, but the mechanisms that determine pubertal timing and underlie its links to disease risk remain unclear. Here, using genome-wide and custom-genotyping arrays in up to 182,416 women of European descent from 57 studies, we found robust evidence (P < 5 × 10(-8)) for 123 signals at 106 genomic loci associated with age at menarche. Many loci were associated with other pubertal traits in both sexes, and there was substantial overlap with genes implicated in body mass index and various diseases, including rare disorders of puberty. Menarche signals were enriched in imprinted regions, with three loci (DLK1-WDR25, MKRN3-MAGEL2 and KCNK9) demonstrating parent-of-origin-specific associations concordant with known parental expression patterns. Pathway analyses implicated nuclear hormone receptors, particularly retinoic acid and γ-aminobutyric acid-B2 receptor signalling, among novel mechanisms that regulate pubertal timing in humans. Our findings suggest a genetic architecture involving at least hundreds of common variants in the coordinated timing of the pubertal transition. PMID:25231870

  7. What is the Age and Origin of the Spherule Bearing Layer in some Ross Sea Cores?

    NASA Astrophysics Data System (ADS)

    Yeh, C.; Abbott, D. H.; Anders, M. H.; Breger, D.

    2012-12-01

    L.P. Khyranina (1985) was the first to suggest that there were two structures present on the Antarctic continental shelf beneath the Ross Sea. One was the ~100 km Bowers impact crater candidate. However, there was no solid evidence that proved an extraterrestrial impact produced the Bowers structure. Debate has ensued for decades on whether the Bowers structure was an impact crater. Now we have come close to finding an answer. We used core samples taken near the crater and sieved into four size fractions (>250,>125,>63,>38 μm). Impact ejecta candidates were then picked from cores ELT 32-08, ELT 32-03, ELT 32-43, ELT 32-06, DSDP 273, DSDP 274, and NPB 95-01 39KC and were analyzed for chemical composition and physical features. All but DSDP site 274 contain pure SiO2 glasses that resemble tektites. We also found candidates for flow textured impact glass and shocked quartz. This led us to conclude that the origin of the spherule-bearing layer was from an impact. With the use of dated core NBP 95-01 39KC, we have constrained the age to lie between 7,305±80 BP and 11,150±95 BP (corrected radiocarbon ages) (Cunningham et al., 1999).

  8. The origin of the Canary Island Seamount Province - New ages of old seamounts

    PubMed Central

    van den Bogaard, Paul

    2013-01-01

    The Canary Island Seamount Province forms a scattered hotspot track on the Atlantic ocean floor ~1300 km long and ~350 km wide, perpendicular to lithospheric fractures, and parallel to the NW African continental margin. New 40Ar/39Ar datings show that seamount ages vary from 133 Ma to 0.2 Ma in the central archipelago, and from 142 Ma to 91 Ma in the southwest. Combining 40Ar/39Ar ages with plate tectonic reconstructions, I find that the temporal and spatial distribution of seamounts is irreconcilable with a deep fixed mantle plume origin, or derivation from passive mantle upwelling beneath a mid-ocean ridge. I conclude that shallow mantle upwelling beneath the Atlantic Ocean basin off the NW African continental lithosphere flanks produced recurrent melting anomalies and seamounts from the Late Jurassic to Recent, nominating the Canary Island Seamount Province as oldest hotspot track in the Atlantic Ocean, and most long-lived preserved on earth. PMID:23838703

  9. The origin of the Canary Island Seamount Province - new ages of old seamounts.

    PubMed

    van den Bogaard, Paul

    2013-01-01

    The Canary Island Seamount Province forms a scattered hotspot track on the Atlantic ocean floor ~1300 km long and ~350 km wide, perpendicular to lithospheric fractures, and parallel to the NW African continental margin. New (40)Ar/(39)Ar datings show that seamount ages vary from 133 Ma to 0.2 Ma in the central archipelago, and from 142 Ma to 91 Ma in the southwest. Combining (40)Ar/(39)Ar ages with plate tectonic reconstructions, I find that the temporal and spatial distribution of seamounts is irreconcilable with a deep fixed mantle plume origin, or derivation from passive mantle upwelling beneath a mid-ocean ridge. I conclude that shallow mantle upwelling beneath the Atlantic Ocean basin off the NW African continental lithosphere flanks produced recurrent melting anomalies and seamounts from the Late Jurassic to Recent, nominating the Canary Island Seamount Province as oldest hotspot track in the Atlantic Ocean, and most long-lived preserved on earth. PMID:23838703

  10. Age and origin of the Gezira alluvial fan between the Blue and White Nile rivers

    NASA Astrophysics Data System (ADS)

    Williams, martin

    2014-05-01

    The Gezira is a low-angle alluvial fan bounded by the Blue Nile to the east and the White Nile to the west. It is the main agricultural region of Sudan and produces high quality long-staple cotton for export. Dark cracking clays (vertisols) cover much of the Gezira and range in age from 50 kyr to Holocene. The Gezira is traversed by a series of defunct sandy channels that originate between Sennar and Wad Medani on the present-day Blue Nile. With a radius of 300 km and an area of 40,000 km2 the Gezira is a mega-fan. The younger channels range in age from early Holocene to 100 kyr, while near surface channels filled with rolled quartz and carbonate gravels have ages back to >250 kyr. Boreholes in the Gezira reveal coarse alluvial sands and gravels in now buried channels overlain by alluvial clays, forming a repetitive sequence of fining-upwards alluvial units. that probably extend back to Pliocene times. The fan is up to 180 m thick with a volume of ~1,800 km3. The sandy or gravelly bed-load channels coincide with colder drier climates and sparse vegetation in the Ethiopian headwaters of the Blue Nile and the alluvial clays denote widespread flooding during times of stronger summer monsoon. The early stages of such flood events were often accompanied by mass burial of Nile oyster (Etheria elliptica) beds, such as the 45-50 kyr floods that deposited up to 5 m of clay in the northern Gezira. A unique feature of the eastern Gezira is a former Blue Nile channel at least 80 km long running parallel to the present river and entirely filled with volcanic ash. The channel was only 3-4 m deep and 20-30 m wide. Very fine laminations and cross-beds, together with locally abundant phytoliths and sponge spicules, suggest slow-moving water, with flow dispersed across many distributary channels. The ash geochemistry is similar to that in the lower part of the Kibish Formation in the lower Omo valley of southern Ethiopia and points to a minimum age of 100 kyr and a maximum age of

  11. COMMUNICATION IN ILLNESS: THE RELATIONSHIP OF NATIONAL ORIGIN TO SYMPTOMS AND DIAGNOSIS.

    PubMed

    MELVILLE, P H; LAXER, R M

    1964-06-27

    This study compares the subjective symptoms recorded by questionnaire, and the diagnoses applied, in 289 adult medical outpatients of six national origins, namely, Canada (Ontario), England, Germany, Hungary, Italy, and Scotland. No significant differences were observed in the number or type of symptoms presented among the national groups. In each group, women and patients with psychological diagnoses reported more symptoms. There were considerable differences in the incidence of somatic (organic) and psychological diagnoses between the groups, which did not reflect equivalent variations in the incidence of definite clinical entities. It is suggested that the symptom habits of the groups studied appeared similar, with the method of investigation used, but that difficulties in patient-physician communication may lead to significantly different diagnostic habits for the national groups involved. PMID:14158552

  12. The National Biological Information Infrastructure: Coming of Age.

    ERIC Educational Resources Information Center

    Cotter, Gladys; Frame, Mike; Sepic, Ron; Zolly, Lisa

    2000-01-01

    Coordinated by the U.S. Geological Survey, the National Biological Information Infrastructure (NBII) is a Web-based system that provides increased access to data and information on the nation's biological resources. This article-an individual case study-addresses the structure of the NBII related to thematic, infrastructure and place-based…

  13. 75 FR 51826 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings...; Aging Bone. Date: September 29, 2010. Time: 11 a.m. to 4 p.m. Agenda: To review and evaluate...

  14. 75 FR 61157 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Panel, Aging Bone and Muscle. Date: November 18, 2010. Time: 1 p.m. to 4:30 p.m. Agenda: To review...

  15. 78 FR 21960 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... Committee: National Institute on Aging Special Emphasis Panel; Presenilins and Alzheimer's Disease. Date..., PARSADANIANA@NIA.NIH.GOV . Name of Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's... Special Emphasis Panel; Alzheimer's Disease Prevention. Date: July 11, 2013. Time: 12 p.m. to 1...

  16. The Role of Social Relationships in Predicting Loneliness: The National Social Life, Health, and Aging Project

    ERIC Educational Resources Information Center

    Shiovitz-Ezra, Sharon; Leitsch, Sara A.

    2010-01-01

    The authors explore associations between objective and subjective social network characteristics and loneliness in later life, using data from the National Social Life, Health, and Aging Project, a nationally representative sample of individuals ages 57 to 85 in the United States. Hierarchical linear regression was used to examine the associations…

  17. 78 FR 64963 - National Institute on Aging; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-30

    ... FR 55752. The meeting has been changed to December 10, 2013, 03:00 p.m. to 07:00 p.m. and December 11... HUMAN SERVICES National Institutes of Health National Institute on Aging; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the Behavior and Social Science of Aging...

  18. 78 FR 66369 - National Institute on Aging; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-05

    ..., Bethesda, MD 20814, which was published in the Federal Register on August 23, 2013, 52552 FR 164. Meeting... HUMAN SERVICES National Institutes of Health National Institute on Aging; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the Neuroscience of Aging Review Committee,...

  19. 78 FR 28237 - National Institute on Aging; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-14

    ... Beach, CA 90802, which was published in the Federal Register on May 3, 2013, 78 FR 26054. The dates of... HUMAN SERVICES National Institutes of Health National Institute on Aging; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the Clinical Aging Review Committee, June 12,...

  20. Developmental Origins of Genotype-Phenotype Correlations in Chronic Diseases of Old Age

    PubMed Central

    McCormack, Shana; Xia, Qianghua; Grant, Struan F.A.

    2012-01-01

    In recent years, genome wide association studies have revolutionized the understanding of the genetic architecture of complex disease, particularly in the context of disorders that present in old age, such as type 2 diabetes and cardiovascular disease. This new era is made all the more compelling by the fact that, through extensive validation efforts, there is now very strong consensus among human geneticists on what the key loci are that contribute to the pathogenesis of these traits. However, as these variants have been almost exclusively uncovered in an adult setting, there is the question of when these genetic variants start exerting their effects; indeed many may start setting up an individual’s predisposition to a disease of old age very early on in life. To this end, we review what breakthroughs have been made in elucidating which of these genetic factors are operating in childhood and conversely what discoveries have actually been made in the pediatric setting that have then been found subsequently to increase one’s risk of a late-onset disease. After all, it well known that complex traits like obesity, type 2 diabetes and inflammatory bowel disease are strongly determined by genetic factors, but the isolation of genes in these complex phenotypes in adults has been impeded by interaction with strong environmental factors. Distillation of the genetic component in these complex traits, which will at least partially have origins in childhood, should be easier to determine in a pediatric setting, where the relatively short period of a child’s lifetime limits the impact of environmental exposure. PMID:23185719

  1. Age, origins and extinctions of the avifauna of Macaronesia: a synthesis of phylogenetic and fossil information

    NASA Astrophysics Data System (ADS)

    Illera, Juan Carlos; Rando, Juan Carlos; Richardson, David S.; Emerson, Brent C.

    2012-09-01

    Understanding the age, origins and extinction of oceanic island biota has captivated the interest of evolutionary biologists since Darwin and Wallace. Because oceanic islands are discrete entities of small geographical size but with considerable habitat diversity, they provide ideal templates within which to study evolutionary processes. The peripheral North Atlantic islands, collectively referred to as Macaronesia, are considered a hot spot of biodiversity due to the fact that they contain a large proportion of endemic taxa (ca 25%). Recent molecular studies are providing insight into the patterns of colonization and radiation within the extant avifauna, while paleontological studies have described many extinct avian species, sometimes identifying the causes and chronology of extinction. The aim of this review is to develop an understanding of the evolutionary and biogeographic history of the macaronesian avifauna, combining information from phylogenetic and paleontological studies. We then compare patterns for Macaronesia with those of other oceanic archipelagos to evaluate to what extent patterns may be generalised across regions. Phylogenetic analyses have confirmed the close relationships between endemic macaronesian avifauna and the closest mainland areas (Europe and Africa), however, in contrast to other archipelagos of a similar age, we show that most extant birds appear to have colonized macaronesian archipelagos relatively recently, within the last four million years, despite some islands being approximately 30 million years old. Fossil records support the idea that higher species richness previously existed, with recent dating on bone collagen of selected extinct species suggesting that their extinction coincided with the arrival of aboriginal people ca 2500 years ago in the Canary Islands, or the arrival of Europeans across all the macaronesian islands in the 14th century. It is plausible that these human mediated extinctions may have selectively acted

  2. Formation waters from Cambrian-age strata, Illinois Basin, USA: Constraints on their origin and evolution

    NASA Astrophysics Data System (ADS)

    Panno, Samuel V.; Hackley, Keith C.; Locke, Randall A.; Krapac, Ivan G.; Wimmer, Bracken; Iranmanesh, Abbas; Kelly, Walton R.

    2013-12-01

    Recently, brine samples from the Cambrian-age Mount Simon Formation (the deepest, most inaccessible sedimentary rock formation of the Illinois Basin) and the overlying Ironton-Galesville Formation were collected as part of a major research effort evaluating the feasibility of sequestration of carbon dioxide in deep geologic formations. Halide and halide/cation ratios (especially Cl/Br and Na/Br ratios) from groundwater samples collected during this investigation suggest that the brines of the Cambrian-age strata formed by the evaporation of seawater well beyond the point of halite precipitation. The Cl/Br and Na/Br ratios, the presence of Mississippi-Valley-Type (MVT) ore mineralization in close proximity to the Illinois Basin, and the tectonic history of the region and the Illinois Basin suggest that components of ore-forming brines and perhaps crystalline basement brine are likely still present within the Mount Simon Formation. Halide and cation/halide ratio plots show that these brines have mixed with and have been diluted by subaerially evaporated seawater, seawater and dilute groundwater. Movement of brines out of the Mount Simon Formation and/or exchange with brines of other formations is constrained by the overlying, siltstone- and shale-rich Eau Claire Formation, a low-permeability layer. The most plausible interpretation of the halide and halide/cation ratio data is that the brines of the Cambrian-age strata were introduced to the Illinois Basin from outside of the basin, perhaps when the Illinois Basin was connected to the Arkoma (Oklahoma and Arkansas) and Black Warrior Basins (Alabama and Mississippi) via the Reelfoot Rift during Cambrian and early Ordovician time. In addition, the presence of some percentage of high NaCl, low Cl/Br brines from the crystalline basement is suggested given the geochemical relationships of the halide and cation/halide ratios and the tectonic history of the Illinois Basin. Finally, halide and cation/halide ratios determined

  3. Genetic evidence for an origin of the Armenians from Bronze Age mixing of multiple populations.

    PubMed

    Haber, Marc; Mezzavilla, Massimo; Xue, Yali; Comas, David; Gasparini, Paolo; Zalloua, Pierre; Tyler-Smith, Chris

    2016-06-01

    The Armenians are a culturally isolated population who historically inhabited a region in the Near East bounded by the Mediterranean and Black seas and the Caucasus, but remain under-represented in genetic studies and have a complex history including a major geographic displacement during World War I. Here, we analyse genome-wide variation in 173 Armenians and compare them with 78 other worldwide populations. We find that Armenians form a distinctive cluster linking the Near East, Europe, and the Caucasus. We show that Armenian diversity can be explained by several mixtures of Eurasian populations that occurred between ~3000 and ~2000 bce, a period characterized by major population migrations after the domestication of the horse, appearance of chariots, and the rise of advanced civilizations in the Near East. However, genetic signals of population mixture cease after ~1200 bce when Bronze Age civilizations in the Eastern Mediterranean world suddenly and violently collapsed. Armenians have since remained isolated and genetic structure within the population developed ~500 years ago when Armenia was divided between the Ottomans and the Safavid Empire in Iran. Finally, we show that Armenians have higher genetic affinity to Neolithic Europeans than other present-day Near Easterners, and that 29% of Armenian ancestry may originate from an ancestral population that is best represented by Neolithic Europeans. PMID:26486470

  4. Magnetic signature of the lunar South Pole-Aitken basin: Character, origin, and age

    NASA Astrophysics Data System (ADS)

    Purucker, Michael E.; Head, James W., III; Wilson, Lionel

    2012-05-01

    A new magnetic map of the Moon, based on Lunar Prospector magnetometer observations, sheds light on the origin of the South Pole-Aitken basin (SPA), the largest and oldest of the recognized lunar basins. A set of WNW-trending linear to arcuate magnetic features, evident in both the radial and scalar observations, covers much of a 1000 km wide region centered on the NW portion of SPA. The source bodies are not at the surface because the magnetic features show no first-order correspondence to any surface topographic or structural feature. Patchy mare basalts of possible late Imbrian-age are emplaced within SPA and are inferred to have been emplaced through dikes, directly from mantle sources. We infer that the magnetic features represent dike swarms that served as feeders for these mare basalts, as evident from the location of the Thomson/Mare Ingenii, Van de Graaff, and Leeuwenhoek mare basalts on the two largest magnetic features in the region. Modeling suggests that the dike zone is between 25 and 50 km wide at the surface, and dike magnetization contrasts are in the range of 0.2 A/m. We theorize that the basaltic dikes were emplaced in the lunar crust when a long-lived dynamo was active. Based on pressure, temperature, and stress conditions prevalent in the lunar crust, dikes are expected to be a dominantly subsurface phenomenon, consistent with the observations reported here.

  5. Genetic evidence for an origin of the Armenians from Bronze Age mixing of multiple populations

    PubMed Central

    Haber, Marc; Mezzavilla, Massimo; Xue, Yali; Comas, David; Gasparini, Paolo; Zalloua, Pierre; Tyler-Smith, Chris

    2016-01-01

    The Armenians are a culturally isolated population who historically inhabited a region in the Near East bounded by the Mediterranean and Black seas and the Caucasus, but remain under-represented in genetic studies and have a complex history including a major geographic displacement during World War I. Here, we analyse genome-wide variation in 173 Armenians and compare them with 78 other worldwide populations. We find that Armenians form a distinctive cluster linking the Near East, Europe, and the Caucasus. We show that Armenian diversity can be explained by several mixtures of Eurasian populations that occurred between ~3000 and ~2000 bce, a period characterized by major population migrations after the domestication of the horse, appearance of chariots, and the rise of advanced civilizations in the Near East. However, genetic signals of population mixture cease after ~1200 bce when Bronze Age civilizations in the Eastern Mediterranean world suddenly and violently collapsed. Armenians have since remained isolated and genetic structure within the population developed ~500 years ago when Armenia was divided between the Ottomans and the Safavid Empire in Iran. Finally, we show that Armenians have higher genetic affinity to Neolithic Europeans than other present-day Near Easterners, and that 29% of Armenian ancestry may originate from an ancestral population that is best represented by Neolithic Europeans. PMID:26486470

  6. On the age and origin of the species flock of haplochromine cichlid fishes of Lake Victoria.

    PubMed

    Fryer, G

    2001-06-01

    Recent suggestions concerning the age and origin of the flock of haplochromine cichlid fishes in Lake Victoria (East Africa) are considered. These accept as proven the suggestion that Lake Victoria dried out completely in the Late Pleistocene, was dry for several thousand years, and refilled ca. 12400 years ago. Apart from the fact that other geophysical evidence contradicts this claim, its biological implications, which do likewise, have never been considered by those who have accepted it. Like those of all previous authors who have seized on the presence of the haplochromine flock of perhaps more than 600 species as evidence of extremely rapid evolution since the lake allegedly refilled, the account completely overlooks the fact that any such desiccation must have eliminated not only the haplochromine cichlids but the entire biota of the lake. Nevertheless, its present fauna not only includes the haplochromines but many other endemic organisms that would not be expected, and whose presence and history demand an explanation if the lake did indeed dry out. No such explanation has been offered, nor does such seem possible. The recent interpretation of events is questioned and rejected. PMID:11375102

  7. On the age and origin of the species flock of haplochromine cichlid fishes of Lake Victoria.

    PubMed Central

    Fryer, G.

    2001-01-01

    Recent suggestions concerning the age and origin of the flock of haplochromine cichlid fishes in Lake Victoria (East Africa) are considered. These accept as proven the suggestion that Lake Victoria dried out completely in the Late Pleistocene, was dry for several thousand years, and refilled ca. 12400 years ago. Apart from the fact that other geophysical evidence contradicts this claim, its biological implications, which do likewise, have never been considered by those who have accepted it. Like those of all previous authors who have seized on the presence of the haplochromine flock of perhaps more than 600 species as evidence of extremely rapid evolution since the lake allegedly refilled, the account completely overlooks the fact that any such desiccation must have eliminated not only the haplochromine cichlids but the entire biota of the lake. Nevertheless, its present fauna not only includes the haplochromines but many other endemic organisms that would not be expected, and whose presence and history demand an explanation if the lake did indeed dry out. No such explanation has been offered, nor does such seem possible. The recent interpretation of events is questioned and rejected. PMID:11375102

  8. Late Cretaceous -Early Tertiary dyke swarm of North Greenland it's age, origins and tectonic significance

    NASA Astrophysics Data System (ADS)

    Manby, Geoffrey

    2014-05-01

    North Greenland is characterized by N-S, NW-SE and E-W trending swarms of mafic dykes which pre- and post date Kap Washington suite of bimodal lavas, ash flows and tuffs. Both rock groups are over-thrust by north vergent thrust sheets of Early Palaeozoic age rocks which record low grade Ellesmerian (Carboniferous) metamorphism and deformation. Laser ablation Ar/Ar ages of 58Ma and 62Ma obtained from thrust fault generated mylonites suggest that magmatism must have effectively ceased by then as no undeformed dykes have been found to cross the thrust planes. High resolution PMAP aeromagnetic surveys for 1989 and 1997-98 show that linear magnetic anomalies parallel to the dense N-S trending dyke swarm of Nansen Land can be traced out onto the Lincoln Sea platform suggesting the dykes are part of the predominantly offshore failed rift magmatic domain which lies central to the southern ends of Alpha ridge, the Lomonosov Ridge, the Markarov Basin, the Amundsen Basin and the Morris-Jessup Plateau. In addition the dykes to the SW of the Mascart Inlet appear to extend undisturbed by faulting 150km onto the Lincoln Sea platform north of Ellesmere Island. The curved ca EW deep negative anomaly which truncates the dyke swarm offshore to the north of the Kap Canon Fault zone together with a similar anomaly along the Harder fjord Fault Zone and its western continuation to the Kap Ramsey Fault appear to constitute the limits of Eurekan thrust belt of North Greenland. Stress tensor analyses of all Eurekan fault plane populations show a consistent N-S to NNW-SSE pure compression pattern orthogonal to the main thrust faults and near parallel to the main dyke trend. Rb/Sr, and Ar/Ar ages obtained from biotite separates, with U/Th ages from apatite-feldspar pairs suggest the dykes range in age from ca 103Ma to 69Ma. The peralkaline affinity of the dyke swarm is similar to that of many other rift generated basalts. Nd, Sr and a small number of Pb isotope ratios have been determined for

  9. Age at Puberty and Father Absence in a National Probability Sample

    ERIC Educational Resources Information Center

    Bogaert, A.F.

    2005-01-01

    The relations between intactness of the parental unit (e.g., father absent at age 14) and pubertal timing in both men and women were examined in a US national probability sample. In both men and women, an absent father at age 14 predicted an earlier age of puberty (e.g., early menarche or voice change). There was little evidence that an absent…

  10. The Origins of Mental Toughness – Prosocial Behavior and Low Internalizing and Externalizing Problems at Age 5 Predict Higher Mental Toughness Scores at Age 14

    PubMed Central

    Sadeghi Bahmani, Dena; Hatzinger, Martin; Gerber, Markus; Lemola, Sakari; Clough, Peter J.; Perren, Sonja; von Klitzing, Kay; von Wyl, Agnes; Holsboer-Trachsler, Edith; Brand, Serge

    2016-01-01

    Background: The concept of mental toughness (MT) has gained increasing importance among groups other than elite athletes by virtue of its psychological importance and explanatory power for a broad range of health-related behaviors. However, no study has focused so far on the psychological origins of MT. Therefore, the aims of the present study were: to explore, to what extent the psychological profiles of preschoolers aged five were associated with both (1) MT scores and (2) sleep disturbances at age 14, and 3) to explore possible gender differences. Method: Nine years after their first assessment at age five (preschoolers), a total of 77 adolescents (mean age: 14.35 years; SD = 1.22; 42% females) took part in this follow-up study. At baseline, both parents and teachers completed the Strengths and Difficulties Questionnaire (SDQ), covering internalizing and externalizing problems, hyperactivity, negative peer relationships, and prosocial behavior. At follow-up, participants completed a booklet of questionnaires covering socio-demographic data, MT, and sleep disturbances. Results: Higher prosocial behavior, lower negative peer relationships, and lower internalizing and externalizing problems at age five, as rated by parents and teachers, were associated with self-reported higher MT and lower sleep disturbances at age 14. At age 14, and relative to males, females had lower MT scores and reported more sleep disturbances. Conclusion: The pattern of results suggests that MT traits during adolescence may have their origins in the pre-school years. PMID:27605919

  11. The Origin of Aging: Imperfectness-Driven Non-Random Damage Defines the Aging Process and Control of Lifespan

    PubMed Central

    Gladyshev, Vadim N.

    2013-01-01

    Physico-chemical properties preclude ideal biomolecules and perfect biological functions. This inherent imperfectness leads to the generation of damage by every biological process, at all levels, from small molecules to cells. The damage is too numerous to be repaired, is partially invisible to natural selection and manifests as aging. I propose that it is the inherent imperfectness of biological systems that is the true root of the aging process. As each biomolecule generates specific forms of damage, the cumulative damage is largely non-random and is indirectly encoded in the genome. I consider this concept in light of other proposed theories of aging and integrate these disparate ideas into a single model. I also discuss the evolutionary significance of damage accumulation and strategies for reducing damage. Finally, I suggest ways to test this integrated model of aging. PMID:23769208

  12. The National Biological Information Infrastructure: Coming of age

    USGS Publications Warehouse

    Cotter, G.; Frame, M.; Sepic, R.; Zolly, L.

    2000-01-01

    Coordinated by the US Geological Survey, the National Biological Information Infrastructure (NBII) is a Web-based system that provides increased access to data and information on the nation's biological resources. The NBII can be viewed from a variety of perspectives. This article - an individual case study and not a broad survey with extensive references to the literature - addresses the structure of the NBII related to thematic sections, infrastructure sections and place-based sections, and other topics such as the Integrated Taxonomic Information System (one of our more innovative tools) and the development of our controlled vocabulary.

  13. A NATIONAL AGENDA ON THE ENVIRONMENT AND THE AGING

    EPA Science Inventory

    By 2030, the number of older Americans is expected to double to 70 million largely as a result of the aging of the baby boomers. The rapid growth in the number of older Americans has many public health implications, including the need to better understand the potential risks p...

  14. A National Study of Residential Care for the Aged.

    ERIC Educational Resources Information Center

    Mor, Vincent; And Others

    1986-01-01

    A national survey of Residential Care Home programs revealed that most facilities were family owned and operated. A provider survey revealed that homes regulated by departments of health were more institutional than were homes regulated by integrated, social service departments. Elderly residents had high satisfaction. (Author/ABB)

  15. Unmarried Boomers Confront Old Age: A National Portrait

    ERIC Educational Resources Information Center

    Lin, I-Fen; Brown, Susan L.

    2012-01-01

    Purpose of the Study: Our study provides a national portrait of the Baby Boom generation, paying particular attention to the heterogeneity among unmarried Boomers and whether it operates similarly among women versus men. Design and Methods: We used the 1980, 1990, and 2000 Census 5% samples and the 2009 American Community Survey (ACS) to document…

  16. [Genetics and anthropology of Caucasian nations and the problem of "caucasoids" origin].

    PubMed

    Nazarova, A F; Aslanishvili, V O; Alkhutov, S M

    2004-01-01

    Anthropological investigations have shown that representatives of European and mongoloid races lived in the river basin of Aragvi from late Stone Age. These data confirm a viewpoint of academician V.P. Alekssev (1974) that population of the Caucasus was compound in race terms from the ancient times. Situation of the Caucasian peoples on the dendrogrammes built corresponds in general to the data of national anthropologists. Clusterization of other europeoid ethnic groups also corresponds in general to the anthropological and historical data and confirms hypothesis which we have set up earlier about differentiation of europeoids, north mongoloids and amerinds of the same population which lived in Asia in palaeolith. PMID:15771089

  17. Kukersite--An oil shale of Ordovician age: Origin, occurrence, and geochemistry

    SciTech Connect

    Bauert, H. . Geology Dept.)

    1992-01-01

    Kukersite is the name originally given to Ordovician oil shale in the Baltic oil shale basin of Estonia. This basin covers about 50,000 sq km and extends eastward to the Leningrad district of Russia. The main oil shale sequence contains up to 50 kukersite beds alternating with argillaceous limestone. They accumulated in Llandeilo-early Caradoc (early Middle Ordovician) during a prominent regression of the Baltoscandian epicontinental sea. This oil shale contains up to 50--60% of total organic carbon. Kukersite consists mostly of accumulations of the microfossil Gloeocapsomorpha prisca, which was apparently an intertidal to very shallow subtidal, marine, mat-forming, benthonic cyanobacterium. Morphological and biogeochemical characteristics show strong similarities with modern mat-forming cyanobacterium Entophysalis major, which can be regarded as a modern analogue for G. prisca. Beside Estonia, the kukersite-type oil shales are known from several sedimentary basins in North America (in Michigan, Illinois, Wisconsin, North Dakota, Oklahoma) and in Australia (Amadeus and Canning basins), and all of these are exclusively of Ordovician age. G. prisca-dominated oil shales have a high hydrocarbon yield and are considered the main source for Ordovician oils in the USA. Hydrocarbons generated from kukersites have certain distinctive geochemical characteristics. These oils have the characteristic predominance of odd carbon number (C[sub 13]-C[sub 19]) n-alkanes with virtual absence of pristane and phytane. The worldwide distribution of kukersites and the related oils points to the fact that shallow-water widespread Ordovician cratonic seas were a favorable environment for C. prisca.

  18. A Comparative Perspective on Intermarriage: Explaining Differences Among National-Origin Groups in the United States

    PubMed Central

    KALMIJN, MATTHIJS; VAN TUBERGEN, FRANK

    2010-01-01

    Little is known about the validity of group-level theories of ethnic intermarriage despite the fact that such theories are often invoked in explaining why certain ethnic groups are “closed,” whereas others are relatively “open.” We develop a comparative perspective by analyzing the marriage choices of 94 national-origin groups in the United States, using pooled data from the Current Population Surveys, 1994–2006, and multilevel models in which individual and contextual determinants of intermarriage are included simultaneously. Our analyses show large differences in endogamy across groups. After taking compositional effects into account, we find that both structural and cultural group-level factors have significant effects on endogamy. Cultural explanations (which focus on the role of norms and preferences) play a more important role than structural explanations (which focus on meeting and mating opportunities). Our results reinforce the common but untested interpretation of endogamy in terms of group boundaries. PMID:20608106

  19. Evolutionary Asiacentrism, Peking man, and the origins of sinocentric ethno-nationalism.

    PubMed

    Yen, Hsiao-Pei

    2014-01-01

    This paper discusses how the theory of evolutionary Asiacentrism and the Peking Man findings at the Zhoukoudian site stimulated Chinese intellectuals to construct Sinocentric ethno-nationalism during the period from the late 1920s to the early 1940s. It shows that the theory was first popularized by foreign scientists in Beijing, and the Peking man discoveries further provided strong evidence for the idea that Central Asia, or to be more specific, Tibet, Xinjiang, and Mongolia, was the original cradle of humans. Chinese scholars in the late 1930s and 1940s appropriated the findings to construct the monogenesis theory of the Chinese, which designated that all the diverse ethnic groups within the territory of China shared a common ancestor back to antiquity. PMID:24771020

  20. 75 FR 14174 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-24

    ...; Principle of Stem Cell Maturation. Date: June 1, 2010. Time: 12 p.m. to 3 p.m. Agenda: To review and... Assistance Program Nos. 93.866, Aging Research, National Institutes of Health, HHS) Dated: March 17,...

  1. 76 FR 34720 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-14

    ... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... Committee: National Institute on Aging Special Emphasis Panel, Frontotemporal Dementia. Date: July 26,...

  2. 78 FR 32408 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-30

    ... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... Committee: National Institute on Aging Special Emphasis Panel Senile Dementia. Date: June 28, 2013. Time:...

  3. The Rocks and Fossils of Glacier National Park: The Story of Their Origin and History

    USGS Publications Warehouse

    Ross, Clyde P.; Rezak, Richard

    1959-01-01

    The story of Glacier National Park begins about 500 million years ago, at a time when there were no mountains in the region - only a vast, exceedingly shallow sea, bordered by desolate plains. The sand, clay, and mud, in part very limy, that were laid down in this sea eventually hardened into the rocks that are now known as the Belt series. These are the principal rocks in the park. Scattered through these rocks are crinkled, limy masses of many forms, the remains of deposits made by colonies of algae. After the Belt series was laid down, successive seas slowly advanced and retreated through long ages across what is now Glacier National Park, burying the Belt rocks under younger ones. After another very long time, a gentle uplift, the forerunner of later events, brought this part of the continent above the reach of sea water for the last time. Much later, some 50 million years ago, the disturbance became far more intense. To climax this upheaval, a mass of rock thousands of feet thick and hundreds of miles long was shoved eastward for 35 miles or more. This tremendous dislocation, well exposed along the eastern boundary of the park, is known as the Lewis overthrust. When the rocks of the region emerged from the sea they began to be attacked by erosion. As successive periods of crustal movement and erosion continued, the younger rocks were slowly stripped off the Belt series and sculpture of the latter by weather and water shaped the early Rocky Mountains. The final episode in the park's geologic past was the ice age, beginning about a million years ago. Repeated advances and retreats of the great glaciers in the high valleys accentuated the mountain terrain and developed the scenic grandeur that is now Glacier National Park. One may say that the park is still in the ice age, for some glaciers still exist. The present report, companion to two more technical reports on the region, informally presents the story of the park's development through past eras for readers

  4. Address by Dr. Robert N. Butler, Director, National Institute on Aging.

    ERIC Educational Resources Information Center

    Butler, Robert N.

    This address by the Director of the National Institute on Aging is a plea for the recognition of the necessity of fundamental research on the aging process. It cautions that new scientific discoveries need to be evaluated more carefully before they are used on humans, and warns that the effects of drugs and treatments on older people may vary from…

  5. 78 FR 5191 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meetings. ]...

  6. 76 FR 63313 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meeting. The...

  7. 75 FR 51082 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meetings....

  8. 78 FR 30932 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Special Emphasis Panel; Heart Failure and Obesity. Date: July 10, 2013. Time: 1:00 p.m. to 5:00...

  9. 78 FR 79706 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-31

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meeting. The...

  10. National Security in the Nuclear Age: Public Library Proposal and Booklist. May 1987 Update.

    ERIC Educational Resources Information Center

    Dane, Ernest B.

    To increase public understanding of national security issues, this document proposes that a balanced and up-to-date collection of books and other materials on national security in the nuclear age be included in all U.S. public libraries. The proposal suggests that the books be grouped together on an identified shelf. Selection criteria for the…

  11. 75 FR 32954 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice...

  12. Personality-Informed Interventions for Healthy Aging: Conclusions from a National Institute on Aging Work Group

    ERIC Educational Resources Information Center

    Chapman, Benjamin P.; Hampson, Sarah; Clarkin, John

    2014-01-01

    We describe 2 frameworks in which personality dimensions relevant to health, such as Conscientiousness, can be used to inform interventions designed to promote health aging. First, contemporary data and theory do not suggest that personality is "immutable," but instead focus on questions of who changes, in what way, why, when, and how.…

  13. Age-of-Recall Effects on Family-of-Origin Ratings.

    ERIC Educational Resources Information Center

    Hampson, Robert B.; And Others

    1994-01-01

    College students (n=141) completed Self-Report Family Inventory on Beavers Systems Model of Family Functioning, rating current family, family when they were 10 years old, and family when they were 16 years old. Found significant differences between age-of-recall groups, with recall ratings from age 10 significantly more competent, cohesive, and…

  14. Possible Origin of Improved High Temperature Performance of Hydrothermally Aged Cu/Beta Zeolite Catalysts

    SciTech Connect

    Peden, Charles HF; Kwak, Ja Hun; Burton, Sarah D.; Tonkyn, Russell G.; Kim, Do Heui; Lee, Jong H.; Jen, H. W.; Cavattaio, Giovanni; Cheng, Yisun; Lambert, Christine

    2012-04-30

    The hydrothermal stability of Cu/beta NH3 SCR catalysts are explored here. In particular, this paper focuses on the interesting ability of this catalyst to maintain and even enhance high-temperature performance for the "standard" SCR reaction after modest (900 °C, 2 hours) hydrothermal aging. Characterization of the fresh and aged catalysts was performed with an aim to identify possible catalytic phases responsible for the enhanced high temperature performance. XRD, TEM and 27Al NMR all showed that the hydrothermally aging conditions used here resulted in almost complete loss of the beta zeolite structure between 1 and 2 hours aging. While the 27Al NMR spectra of 2 and 10 hour hydrothermally-aged catalysts showed significant loss of a peak associated with tetrahedrally-coordinated Al species, no new spectral features were evident. Two model catalysts, suggested by these characterization data as possible mimics of the catalytic phase formed during hydrothermal aging of Cu/beta, were prepared and tested for their performance in the "standard" SCR and NH3 oxidation reactions. The similarity in their reactivity compared to the 2 hour hydrothermally-aged Cu/beta catalyst suggests possible routes for preparing multi-component catalysts that may have wider temperature windows for optimum performance than those provided by current Cu/zeolite catalysts.

  15. [Depression in old age, part 1 : Origin, clinical symptoms, diagnosis and interaction between depression and dementia].

    PubMed

    Wolter, Dirk K

    2016-06-01

    Depression is one of the most frequent mental disorders in old age. A huge variety of very different causal factors can contribute to late life depression as a common final outcome. The pathogenic pathways of depression overlap with those of frequent somatic medical conditions, such as diabetes and ischemic heart disease. Age-specific modulations of symptom presentation are described in this article with special emphasis on subthreshold depression and the complex mutual relationship between depression and dementia is presented. PMID:26809853

  16. Reactive nitrogen oxides in the southeast United States national parks: source identification, origin, and process budget

    NASA Astrophysics Data System (ADS)

    Tong, Daniel Quansong; Kang, Daiwen; Aneja, Viney P.; Ray, John D.

    2005-01-01

    We present in this study both measurement-based and modeling analyses for elucidation of source attribution, influence areas, and process budget of reactive nitrogen oxides at two rural southeast United States sites (Great Smoky Mountains national park (GRSM) and Mammoth Cave national park (MACA)). Availability of nitrogen oxides is considered as the limiting factor to ozone production in these areas and the relative source contribution of reactive nitrogen oxides from point or mobile sources is important in understanding why these areas have high ozone. Using two independent observation-based techniques, multiple linear regression analysis and emission inventory analysis, we demonstrate that point sources contribute a minimum of 23% of total NOy at GRSM and 27% at MACA. The influence areas for these two sites, or origins of nitrogen oxides, are investigated using trajectory-cluster analysis. The result shows that air masses from the West and Southwest sweep over GRSM most frequently, while pollutants transported from the eastern half (i.e., East, Northeast, and Southeast) have limited influence (<10% out of all air masses) on air quality at GRSM. The processes responsible for formation and removal of reactive nitrogen oxides are investigated using a comprehensive 3-D air quality model (Multiscale Air Quality SImulation Platform (MAQSIP)). The NOy contribution associated with chemical transformations to NOz and O3, based on process budget analysis, is as follows: 32% and 84% for NOz, and 26% and 80% for O3 at GRSM and MACA, respectively. The similarity between NOz and O3 process budgets suggests a close association between nitrogen oxides and effective O3 production at these rural locations.

  17. The Origin of a Killer Revealed by Bronze Age Yersinia Genomes.

    PubMed

    Nelson-Sathi, Shijulal; Martin, William F

    2015-11-11

    Bubonic plaque is caused by Yersinia pestis, a deadly pathogen that left deep scars in human history. Rasmussen et al. (2015) have now retrieved Y. pestis genomes from 2,800- to 5,000-year-old human teeth, shedding new light on origins of the strain that brought Black Death to Europe 670 years ago. PMID:26567502

  18. Age Changes in Personality and Their Origins: Comment on Roberts, Walton, and Viechtbauer (2006)

    ERIC Educational Resources Information Center

    Costa, Paul T.; McCrae, Robert R.

    2006-01-01

    This article presents comments on the original article "Patterns of Mean-Level Change in Personality Traits Across the Life Course: A Meta-Analysis of Longitudinal Studies," by B. W. Roberts, K. W. Walton, and W. Viechtbauer. Although Roberts et al depicted the present authors as proponents of the immutability of traits, in fact we have always…

  19. Personality-Informed Interventions for Healthy Aging: Conclusions From a National Institute on Aging Workgroup

    PubMed Central

    Chapman, Benjamin P.; Hampson, Sarah; Clarkin, John

    2013-01-01

    We describe two frameworks in which personality dimensions relevant to health, such as Conscientiousness, can be used to inform interventions designed to promote health aging. First, contemporary data and theory do not suggest that personality is “immutable”, but instead focus on questions of who changes, in what way, why, when, and how. In fact, the notion that personality could be changed was part and parcel of many schools of psychotherapy, which suggested that long term and meaningful change in symptoms could not be achieved without change in relevant aspects of personality. We review intervention research documenting change in personality. Based on an integrative view of personality as a complex system, we describe a “bottom-up” model of change in which interventions to change basic personality processes eventuate in changes at the trait level. A second framework leverages the descriptive and predictive power of personality to tailor individual risk prediction and treatment, as well as refine public health programs, to the relevant dispositional characteristics of the target population. These methods dovetail with and add a systematic and rigorous psychosocial dimension to the personalized medicine and patient-centeredness movements in medicine. In addition to improving health through earlier intervention and increased fit between treatments and persons, cost-effectiveness improvements can be realized by more accurate resource allocation. Numerous examples from the personality, health, and aging literature on Conscientiousness and other traits are provided throughout, and we conclude with a series of recommendations for research in these emerging areas. PMID:23978300

  20. Personality-informed interventions for healthy aging: conclusions from a National Institute on Aging work group.

    PubMed

    Chapman, Benjamin P; Hampson, Sarah; Clarkin, John

    2014-05-01

    We describe 2 frameworks in which personality dimensions relevant to health, such as Conscientiousness, can be used to inform interventions designed to promote health aging. First, contemporary data and theory do not suggest that personality is "immutable," but instead focus on questions of who changes, in what way, why, when, and how. In fact, the notion that personality could be changed was part and parcel of many schools of psychotherapy, which suggested that long-term and meaningful change in symptoms could not be achieved without change in relevant aspects of personality. We review intervention research documenting change in personality. On the basis of an integrative view of personality as a complex system, we describe a bottom-up model of change in which interventions to change basic personality processes eventuate in changes at the trait level. A 2nd framework leverages the descriptive and predictive power of personality to tailor individual risk prediction and treatment, as well as refine public health programs, to the relevant dispositional characteristics of the target population. These methods dovetail with, and add a systematic and rigorous psychosocial dimension to, the personalized medicine and patient-centeredness movements in medicine. In addition to improving health through earlier intervention and increased fit between treatments and persons, cost-effectiveness improvements can be realized by more accurate resource allocation. Numerous examples from the personality, health, and aging literature on Conscientiousness and other traits are provided throughout, and we conclude with a series of recommendations for research in these emerging areas. PMID:23978300

  1. Behavioral Autonomy Age Expectations among Mexican-Origin Mother-Daughter Dyads: An Examination of Within-Group Variability

    PubMed Central

    Bámaca-Colbert, Mayra Y.; Umaña-Taylor, Adriana J.; Espinosa-Hernández, Graciela; Brown, Ashley M.

    2011-01-01

    This study examined differences in behavioral autonomy age expectations between Mexican-origin mothers and their adolescent daughters (N = 319 dyads); variability in behavioral autonomy age expectations as a function of nativity and maternal educational attainment also was examined. Findings indicated significant differences between mothers and daughters such that mothers reported later expectations for the timing of behavioral autonomy than did daughters. Follow-up analyses indicated that findings appeared to be driven by maternal nativity, with dyads comprised of Mexico-born mothers reporting the latest age expectations for behavioral autonomy when compared with dyads comprised of U.S.-born mothers. Findings underscore the need to examine normative development among Latino adolescents and their families with a specific focus on how sociocultural characteristics can contribute to within-family differences. PMID:22093152

  2. U/Pb age and origin of supergene uranophane-beta from the Borborema Pegmatite Mineral Province, Brazil

    NASA Astrophysics Data System (ADS)

    Dill, H. G.; Hansen, B. T.; Weber, B.

    2013-08-01

    Uranophane-beta of supergene origin formed in the Borborema Pegmatite Mineral. Province, which is situated in the north-easternmost part of Brazil. The sampling site lies in the topmost parts of the Quintos Pegmatite, about ten kilometers north of the town of Equador. The uranyl silicate was investigated for its age and physical chemical regime of formation. Age dating yielded a U/Pb age of 6.77 ± 0.61 Ma. Uranophane has been derived together with autunite from weathering of brannerite in a tropical climate under alternating wet and dry seasons, when the pH was below 8. This canary-yellow well-crystallized uranyl silicate can be used as a physical chemical marker as well as a clock for supergene alteration.

  3. Motivational Shifts in Aging Monkeys and the Origins of Social Selectivity.

    PubMed

    Almeling, Laura; Hammerschmidt, Kurt; Sennhenn-Reulen, Holger; Freund, Alexandra M; Fischer, Julia

    2016-07-11

    As humans age, they become more selective regarding their personal goals [1] and social partners [2]. Whereas the selectivity in goals has been attributed to losses in resources (e.g., physical strength) [3], the increasing focus on emotionally meaningful partners is, according to socioemotional selectivity theory, driven by the awareness of one's decreasing future lifetime [2]. Similar to humans, aging monkeys show physical losses [4] and reductions in social activity [2, 5-7]. To disentangle a general resource loss and the awareness of decreasing time, we combined field experiments with behavioral observations in a large age-heterogeneous population of Barbary macaques (Macaca sylvanus) at La Forêt des Singes. Novel object tests revealed a loss of interest in the nonsocial environment in early adulthood, which was modulated by the availability of a food reward. Experiments using vocal and visual representations of social partners indicated that monkeys maintained an interest in social stimuli and a preferential interest in friends and socially important individuals into old age. Old females engaged in fewer social interactions, although other group members continued to invest in relationships with them. Consequently, reductions in sociality were not due to a decrease in social interest. In conclusion, some of the motivational shifts observed in aging humans, particularly the increasing focus on social over nonsocial stimuli, may occur in the absence of a limited time perspective and are most likely deeply rooted in primate evolution. Our findings highlight the value of nonhuman primates as valuable models for understanding human aging [8, 9]. PMID:27345168

  4. The age and origin of the Pacific islands: a geological overview.

    PubMed

    Neall, Vincent E; Trewick, Steven A

    2008-10-27

    The Pacific Ocean evolved from the Panthalassic Ocean that was first formed ca 750 Ma with the rifting apart of Rodinia. By 160 Ma, the first ocean floor ascribed to the current Pacific plate was produced to the west of a spreading centre in the central Pacific, ultimately growing to become the largest oceanic plate on the Earth. The current Nazca, Cocos and Juan de Fuca (Gorda) plates were initially one plate, produced to the east of the original spreading centre before becoming split into three. The islands of the Pacific have originated as: linear chains of volcanic islands on the above plates either by mantle plume or propagating fracture origin, atolls, uplifted coralline reefs, fragments of continental crust, obducted portions of adjoining lithospheric plates and islands resulting from subduction along convergent plate margins. Out of the 11 linear volcanic chains identified, each is briefly described and its history summarized. The geology of 10 exemplar archipelagos (Japan, Izu-Bonin, Palau, Solomons, Fiji, New Caledonia, New Zealand, Society, Galápagos and Hawaii) is then discussed in detail. PMID:18768382

  5. Age and origin of carlsbad cavern and related caves from 40Ar/39Ar of alunite

    PubMed

    Polyak; McIntosh; Guven; Provencio

    1998-03-20

    40Ar/39Ar dating of fine-grained alunite that formed during cave genesis provides ages of formation for the Big Room level of Carlsbad Cavern [4.0 to 3.9 million years ago (Ma)], the upper level of Lechuguilla Cave (6.0 to 5.7 Ma), and three other hypogene caves (11.3 to 6.0 Ma) in the Guadalupe Mountains of New Mexico. Alunite ages increase and are strongly correlative with cave elevations, which indicates an 1100-meter decline in the water table, apparently related to tectonic uplift and tilting, from 11.3 Ma to the present. 40Ar/39Ar dating studies of the hypogene caves have the potential to help resolve late Cenozoic climatic, speleologic, and tectonic questions. PMID:9506939

  6. The origin of early age expansions induced in cementitious materials containing shrinkage reducing admixtures

    SciTech Connect

    Sant, Gaurav; Lothenbach, Barbara; Juilland, Patrick; Le Saout, Gwenn; Weiss, Jason; Scrivener, Karen

    2011-03-15

    Studies on the early-age shrinkage behavior of cement pastes, mortars, and concretes containing shrinkage reducing admixtures (SRAs) have indicated these mixtures frequently exhibit an expansion shortly after setting. While the magnitude of the expansion has been noted to be a function of the chemistry of the cement and the admixture dosage; the cause of the expansion is not clearly understood. This investigation uses measurements of autogenous deformation, X-ray diffraction, pore solution analysis, thermogravimetry, and scanning electron microscopy to study the early-age properties and describe the mechanism of the expansion in OPC pastes made with and without SRA. The composition of the pore solution indicates that the presence of the SRA increases the portlandite oversaturation level in solution which can result in higher crystallization stresses which could lead to an expansion. This observation is supported by deformation calculations for the systems examined.

  7. Origin, variability and age of biomass burning plumes intercepted during BORTAS-B

    NASA Astrophysics Data System (ADS)

    Finch, D. P.; Palmer, P. I.; Parrington, M.

    2014-03-01

    We use the GEOS-Chem atmospheric chemistry transport model to interpret aircraft measurements of carbon monoxide (CO) in biomass burning outflow taken during the 2011 BORTAS-B campaign over eastern Canada. The model has some skill reproducing the observed variability (r = 0.45) but has a negative bias for observations below 100 ppb and a positive bias above 300 ppb. We find that observed CO variations are largely due to NW North American biomass burning, as expected, with smaller and less variable contributions from fossil fuel combustion from eastern Asia and NE North America. To help interpret observed variations of CO we develop an Eulerian effective age of emissions (A) metric, accounting for mixing and chemical decay, which we apply to pyrogenic emissions of CO. We find that during BORTAS-B the age of emissions intercepted over Halifax, Nova Scotia is typically 4-11 days, and on occasion as young as two days. We show that A is typically 1-5 days older than the associated photochemical ages inferred from colocated measurements of different hydrocarbons. We find that the median difference between the age measures (Δτ) in plumes (CH3CN > 150 ppt) peaks at 3-5 days corresponding to a chemical retardation of 50%. We find a strong relationship in plumes between A and Δτ (r2 = 0.60), which is not evident outwith these plumes (r2 = 0.23). We argue that these observed relationships, together with a robust observed relationship between CO and black carbon aerosol during BORTAS-B (r2 > 0.7), form the basis of indirect evidence that aerosols co-emitted with gases during pyrolysis markedly slowed down the plume photochemistry during BORTAS-B with respect to photochemistry at the same latitude and altitude in clear skies.

  8. Apoptosis: its origin, history, maintenance and the medical implications for cancer and aging

    NASA Astrophysics Data System (ADS)

    Kaczanowski, Szymon

    2016-06-01

    Programmed cell death is a basic cellular mechanism. Apoptotic-like programmed cell death (called apoptosis in animals) occurs in both unicellular and multicellular eukaryotes, and some apoptotic mechanisms are observed in bacteria. Endosymbiosis between mitochondria and eukaryotic cells took place early in the eukaryotic evolution, and some of the apoptotic-like mechanisms of mitochondria that were retained after this event now serve as parts of the eukaryotic apoptotic machinery. Apoptotic mechanisms have several functions in unicellular organisms: they include kin-selected altruistic suicide that controls population size, sharing common goods, and responding to viral infection. Apoptotic factors also have non-apoptotic functions. Apoptosis is involved in the cellular aging of eukaryotes, including humans. In addition, apoptosis is a key part of the innate tumor-suppression mechanism. Several anticancer drugs induce apoptosis, because apoptotic mechanisms are inactivated during oncogenesis. Because of the ancient history of apoptosis, I hypothesize that there is a deep relationship between mitochondrial metabolism, its role in aerobic versus anaerobic respiration, and the connection between apoptosis and cancer. Whereas normal cells rely primarily on oxidative mitochondrial respiration, most cancer cells use anaerobic metabolism. According to the Warburg hypothesis, the remodeling of the metabolism is one of the processes that leads to cancer. Recent studies indicate that anaerobic, non-mitochondrial respiration is particularly active in embryonic cells, stem cells, and aggressive stem-like cancer cells. Mitochondrial respiration is particularly active during the pathological aging of human cells in neurodegenerative diseases. According to the reversed Warburg hypothesis formulated by Demetrius, pathological aging is induced by mitochondrial respiration. Here, I advance the hypothesis that the stimulation of mitochondrial metabolism leads to pathological aging.

  9. Apoptosis: its origin, history, maintenance and the medical implications for cancer and aging.

    PubMed

    Kaczanowski, Szymon

    2016-01-01

    Programmed cell death is a basic cellular mechanism. Apoptotic-like programmed cell death (called apoptosis in animals) occurs in both unicellular and multicellular eukaryotes, and some apoptotic mechanisms are observed in bacteria. Endosymbiosis between mitochondria and eukaryotic cells took place early in the eukaryotic evolution, and some of the apoptotic-like mechanisms of mitochondria that were retained after this event now serve as parts of the eukaryotic apoptotic machinery. Apoptotic mechanisms have several functions in unicellular organisms: they include kin-selected altruistic suicide that controls population size, sharing common goods, and responding to viral infection. Apoptotic factors also have non-apoptotic functions. Apoptosis is involved in the cellular aging of eukaryotes, including humans. In addition, apoptosis is a key part of the innate tumor-suppression mechanism. Several anticancer drugs induce apoptosis, because apoptotic mechanisms are inactivated during oncogenesis. Because of the ancient history of apoptosis, I hypothesize that there is a deep relationship between mitochondrial metabolism, its role in aerobic versus anaerobic respiration, and the connection between apoptosis and cancer. Whereas normal cells rely primarily on oxidative mitochondrial respiration, most cancer cells use anaerobic metabolism. According to the Warburg hypothesis, the remodeling of the metabolism is one of the processes that leads to cancer. Recent studies indicate that anaerobic, non-mitochondrial respiration is particularly active in embryonic cells, stem cells, and aggressive stem-like cancer cells. Mitochondrial respiration is particularly active during the pathological aging of human cells in neurodegenerative diseases. According to the reversed Warburg hypothesis formulated by Demetrius, pathological aging is induced by mitochondrial respiration. Here, I advance the hypothesis that the stimulation of mitochondrial metabolism leads to pathological aging

  10. Internal versus external controls on age variability: Definitions, origins and implications in a changing climate

    NASA Astrophysics Data System (ADS)

    Helton, A. M.; Poole, G. C.; Payn, R. A.; Izurieta, C.; Wright, M.; Bernhardt, E. S.; Stanford, J. A.

    2014-12-01

    The unsteadiness of stream water age is now well established, but the controls on the age dynamics, and the adequate representation and prediction of those dynamics, are not. A basic distinction can be made between internal variability that arises from changes in the proportions of flow moving through the diverse flow pathways of a hydrologic system, and external variability that arises from the stochasticity of inputs and outputs (such as precipitation and streamflow). In this talk I will show how these two types of age variability can be formally defined and distinguished within the framework of rank StorAge Selection (rSAS) functions. Internal variability implies variations in time in the rSAS function, while external variability does not. This leads naturally to the definition of several modes of internal variability, reflecting generic ways that system flowpaths may be rearranged. This rearrangement may be induced by fluctuations in the system state (such as catchment wetness), or by longer-term changes in catchment structure (such as land use change). One type of change, the 'inverse storage effect' is characterized by an increase in the release of young water from the system in response to an increase in overall system storage. This effect can be seen in many hydrologic settings, and has important implications for the effect of altered hydroclimatic conditions on solute transport through a landscape. External variability, such as increased precipitation, can induce a decrease in mean transit time (and vice versa), but this effect is greatly enhanced if accompanied by an internal shift in flow pathways that increases the relative importance of younger water. These effects will be illustrated using data from field and experimental studies.

  11. Origin of the slow dynamics and the aging of a soft glass.

    PubMed

    Mazoyer, Sylvain; Cipelletti, Luca; Ramos, Laurence

    2006-12-01

    We study by light microscopy a soft glass consisting of a compact arrangement of polydisperse multilamellar vesicles. We show that its slow and nonstationary dynamics results from the unavoidable small fluctuations of temperature, which induce intermittent local shear deformations in the sample, because of thermal expansion and contraction. Temperature-induced shear provokes both reversible and irreversible rearrangements whose amplitude decreases with time, leading to an exponential slowing down of the dynamics with sample age. PMID:17280252

  12. Frictional ageing from interfacial bonding and the origins of rate and state friction.

    PubMed

    Li, Qunyang; Tullis, Terry E; Goldsby, David; Carpick, Robert W

    2011-12-01

    Earthquakes have long been recognized as being the result of stick-slip frictional instabilities. Over the past few decades, laboratory studies of rock friction have elucidated many aspects of tectonic fault zone processes and earthquake phenomena. Typically, the static friction of rocks grows logarithmically with time when they are held in stationary contact, but the mechanism responsible for this strengthening is not understood. This time-dependent increase of frictional strength, or frictional ageing, is one manifestation of the 'evolution effect' in rate and state friction theory. A prevailing view is that the time dependence of rock friction results from increases in contact area caused by creep of contacting asperities. Here we present the results of atomic force microscopy experiments that instead show that frictional ageing arises from the formation of interfacial chemical bonds, and the large magnitude of ageing at the nanometre scale is quantitatively consistent with what is required to explain observations in macroscopic rock friction experiments. The relative magnitude of the evolution effect compared with that of the 'direct effect'--the dependence of friction on instantaneous changes in slip velocity--determine whether unstable slip, leading to earthquakes, is possible. Understanding the mechanism underlying the evolution effect would enable us to formulate physically based frictional constitutive laws, rather than the current empirically based 'laws', allowing more confident extrapolation to natural faults. PMID:22139421

  13. Age and origin of the Cortlandt Complex, New York: Implications from Sm-Nd data

    USGS Publications Warehouse

    Domenick, M.A.; Basu, A.R.

    1982-01-01

    Sm-Nd systematics for nine whole-rock samples of hornblende norites, pyroxenites and a lamprophyre from various parts of the Cortlandt Complex were analyzed. Six of these samples from the central and eastern parts of the complex give an isochron age of 430??34 (2 ??) Ma with an e{open}Nd value of -2.9??0.5, and the other three samples from the western part, including the lamprophyre, define a similar age of 394??33 (2 ??) Ma but with a distinctly different e{open}Nd value of -1.4??0.4. The two different initial 143Nd/144Nd ratios corresponding to these e{open}-values are interpreted to reflect continental crustal contamination of the lamprophyric parental liquid prior to final emplacement and crystal fractionation to produce the different rock types of the complex. The intrusion age of 430 Ma for the complex clearly post-dates the major metamorphic event of the Taconic orogeny. The Nd-isotopic data also suggest a relationship between the Cortlandt Complex and a belt of lamprophyric dike rocks to the west, known as the Beemerville trend, which cuts across the metamorphic trends of the Taconic (Ratcliffe 1981). ?? 1982 Springer-Verlag.

  14. Perceptions of Female and Male Superintendents for a Middle School Principalship as Moderated by Sex and National Origin of Applicants

    ERIC Educational Resources Information Center

    Young, Phillip; Young, Karen Holsey

    2010-01-01

    A 2 x 2 x 2 factorial design involving sex of superintendents, sex of applicants, and national origin of applicants (Hispanic vs. non-Hispanic) is used to assess screening decisions for a middle school principalship. Screening decisions are analyzed from a sequential model to capture selection as a process. Results indicate that biases surface…

  15. 34 CFR 270.6 - What limitation is imposed on providing race and national origin desegregation assistance under...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 1 2012-07-01 2012-07-01 false What limitation is imposed on providing race and... EDUCATION DESEGREGATION OF PUBLIC EDUCATION § 270.6 What limitation is imposed on providing race and... this section, a recipient of a grant for race or national origin desegregation assistance under...

  16. 34 CFR 270.6 - What limitation is imposed on providing race and national origin desegregation assistance under...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 1 2011-07-01 2011-07-01 false What limitation is imposed on providing race and... EDUCATION DESEGREGATION OF PUBLIC EDUCATION § 270.6 What limitation is imposed on providing race and... this section, a recipient of a grant for race or national origin desegregation assistance under...

  17. 34 CFR 270.6 - What limitation is imposed on providing race and national origin desegregation assistance under...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 1 2013-07-01 2013-07-01 false What limitation is imposed on providing race and... EDUCATION DESEGREGATION OF PUBLIC EDUCATION § 270.6 What limitation is imposed on providing race and... this section, a recipient of a grant for race or national origin desegregation assistance under...

  18. 34 CFR 270.6 - What limitation is imposed on providing race and national origin desegregation assistance under...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 1 2014-07-01 2014-07-01 false What limitation is imposed on providing race and... EDUCATION DESEGREGATION OF PUBLIC EDUCATION § 270.6 What limitation is imposed on providing race and... this section, a recipient of a grant for race or national origin desegregation assistance under...

  19. 34 CFR 270.6 - What limitation is imposed on providing race and national origin desegregation assistance under...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false What limitation is imposed on providing race and... EDUCATION DESEGREGATION OF PUBLIC EDUCATION § 270.6 What limitation is imposed on providing race and... this section, a recipient of a grant for race or national origin desegregation assistance under...

  20. Depressed rates of origination and extinction during the late Paleozoic ice age: A new state for the global marine ecosystem

    NASA Astrophysics Data System (ADS)

    Stanley, Steven M.; Powell, Matthew G.

    2003-10-01

    Rates of origination and extinction for marine animal genera dropped to low levels in latest Mississippian time, immediately after massive glaciers formed in the Southern Hemisphere and a second-order mass extinction occurred. Evolutionary turnover and diversity remained low for ˜50 m.y., shifting markedly upward precisely when extensive glaciation ended in Early Permian time. All diverse taxa with good fossil records experienced low rates of origination and extinction during this major ice age. Such sluggish rates would be predicted for faunas of shallow seas on or adjacent to a heavily glaciated supercontinent such as Pangea, where cool and highly seasonal thermal regimes should dictate that species have broad ecological niches, widespread geographic distributions, and large and relatively stable populations.

  1. IODP Expedition 351 Izu-Bonin-Mariana Arc Origins: Age model for Site U1438

    NASA Astrophysics Data System (ADS)

    Morris, Antony; Maffione, Marco; Kender, Sev; Aljahdali, Mohammed; Bandini, Alexandre; Guerra, Rodrigo do Monte

    2015-04-01

    We report preliminary paleomagnetic and paleontological results from International Ocean Discovery Program (IODP) Expedition 351, which recovered an unprecedented ~1.4 km thick volcaniclastic sedimentary record documenting the initiation and subsequent evolution of the Izu-Bonin-Mariana (IBM) intra-oceanic arc-basin system. Magnetostratigraphic and biostratigraphic constraints provide a high-resolution temporal framework for interpretation of this record. Paleomagnetic analyses of archive half core samples provide a continuous record of the geomagnetic field inclination down to 847 mbsf that allows construction of a detailed site magnetostratigraphy that closely matches the Geomagnetic Polarity Timescale (Gradstein et al., 2012). A total of 87 geomagnetic reversals have been recognized in the studied succession, extending back to ~36 Ma. Despite sporadic microfossil occurrences in parts, calcareous nannofossils, planktonic foraminifera and radiolarians each contribute to the age model for the entire Site. All nannofossil marker species for Oligocene to Eocene Zones NP25 to NP19/20 are recognised. Beneath paleomagnetic control (847-1449 mbsf), foraminifera and radiolarians provide the only age control. The most salient features of the age model are that: (i) average linear sedimentation rates during the Plio-Pleistocene range from 1.4 to 2.2 cm/ka; (ii) there was a reduction in sedimentation rates to 0.25 - 0.5 cm/ka throughout the Miocene; and (iii) sedimentation rates sharply increase again in the Oligocene to Late Eocene to a maximum of ~20 cm/ka. These quantitative constraints closely match (non-quantitative) inferences based on the lithostratigraphy of the site, with fine-grained/coarse-grained sediments dominating in periods with low/high sedimentation rates respectively.

  2. IODP Expedition 351 Izu-Bonin-Mariana Arc Origins: Age Model for Site U1438

    NASA Astrophysics Data System (ADS)

    Morris, A.; Aljahdali, M. H.; Bandini, A. N.; do Monte Guerra, R.; Kender, S.; Maffione, M.

    2014-12-01

    We report preliminary paleomagnetic and paleontological results from International Ocean Discovery Program (IODP) Expedition 351, which recovered an unprecedented ~1.4 km thick volcaniclastic sedimentary record documenting the initiation and subsequent evolution of the Izu-Bonin-Mariana (IBM) intra-oceanic arc-basin system. Magnetostratigraphic and biostratigraphic constraints provide a high-resolution temporal framework for interpretation of this record.Paleomagnetic analyses of archive half core samples provide a continuous record of the geomagnetic field inclination down to 847 mbsf that allows construction of a detailed site magnetostratigraphy that closely matches the Geomagnetic Polarity Timescale (Gradstein et al., 2012). A total of 87 geomagnetic reversals have been recognized in the studied succession, extending back to ~36 Ma. Despite sporadic microfossil occurrences in parts, calcareous nannofossils, planktonic foraminifera and radiolarians each contribute to the age model for the entire Site. All nannofossil marker species for Oligocene to Eocene Zones NP25 to NP19/20 are recognised. Beneath paleomagnetic control (847-1449 mbsf), foraminifera and radiolarians provide the only age control.The most salient features of the age model are that: (i) average linear sedimentation rates during the Plio-Pleistocene range from 1.4 to 2.2 cm/ka; (ii) there was a reduction in sedimentation rates to 0.25 - 0.5 cm/ka throughout the Miocene; and (iii) sedimentation rates sharply increase again in the Oligocene to Late Eocene to a maximum of ~20 cm/ka. These quantitative constraints closely match (non-quantitative) inferences based on the lithostratigraphy of the site, with fine-grained/coarse-grained sediments dominating in periods with low/high sedimentation rates respectively.

  3. Origin, variability and age of biomass burning plumes intercepted during BORTAS-B

    NASA Astrophysics Data System (ADS)

    Finch, D. P.; Palmer, P. I.; Parrington, M.

    2014-12-01

    We use the GEOS-Chem atmospheric chemistry transport model to interpret aircraft measurements of carbon monoxide (CO) in biomass burning outflow taken during the 2011 BORTAS-B campaign over eastern Canada. The model has some skill reproducing the observed variability, with a Spearman's rank correlation rs = 0.65, but has a positive negative bias for observations <100 ppb and a negative bias for observations > 300 ppb. We find that observed CO variations are largely due to fires over Ontario, as expected, with smaller and less variable contributions from fossil fuel combustion from eastern Asia and NE North America. To help interpret observed variations of CO we develop a Eulerian effective physical age of emissions (A) metric, accounting for mixing and chemical decay, which we apply to pyrogenic emissions of CO. We find that during BORTAS-B the age of emissions intercepted over Halifax, Nova Scotia is typically 4-11 days, and on occasion as young as two days. We show that A is typically 1-5 days older than the associated photochemical ages inferred from co-located measurements of different hydrocarbons. We find that the frequency distribution of differences between the age measures (Δτ) in plumes (defined by CH3CN > 150 ppt) peaks at 3 days. This corresponds to a chemical retardation of 50%. We find a strong relationship in biomass burning plumes between A and Δτ (r2 = 0.80), which is not present outwith these plumes (r2 = 0.28). We argue that these observed relationships, together with a robust observed relationship between CO and black carbon aerosol during BORTAS-B (r2 > 0.7), form the basis of indirect evidence that aerosols co-emitted with gases during pyrolysis markedly slowed down the plume photochemistry during BORTAS-B with respect to photochemistry at the same latitude and altitude in

  4. Cystic Fibrosis in Ukraine: age, origin and tracing of the delta F508 mutation.

    PubMed

    Livshits, L A; Kravchenko, S A

    1996-12-01

    Seven already known CF mutations were searched in 170 unrelated cystic fibrosis patients from different regions of Ukraine. Their frequencies in this sample were: delta F508-50%, 1677delTA-0.3% (10th exon), R553X-0.6%, G551D-0.3% (11th exon), R334W-0.6% (7th exon). 1154insTC (7th exon) and S549I (11th exon) were not found. Heterozygotes for delta F508 were searched in 865 healthy volunteers from different Ukranian regions. Their frequencies ranged from 1:28 to 1:70. We report here unpublished population data from Ukraine in order to discuss the origin, evolution and dispersion of chromosomes bearing the delta F508 mutation. Selection in terms of heterozygote advantage is also discussed. PMID:9263776

  5. Ribosome origins: The relative age of 23S rRNA Domains

    NASA Astrophysics Data System (ADS)

    Hury, James; Nagaswamy, Uma; Larios-Sanz, Maia; Fox, George E.

    2006-08-01

    The modern ribosome and its component RNAs are quite large and it is likely that at an earlier time they were much smaller. Hence, not all regions of the modern ribosomal RNAs (rRNA) are likely to be equally old. In the work described here, it is hypothesized that the oldest regions of the RNAs will usually be highly integrated into the machinery. When this is the case, an examination of the interconnectivity between local RNA regions can provide insight to the relative age of the various regions. Herein, we describe an analysis of all known long-range RNA/RNA interactions within the 23S rRNA and between the 23S rRNA and the 16S rRNA in order to assess the interconnectivity between the usual Domains as defined by secondary structure. Domain V, which contains the peptidyl transferase center is centrally located, extensively connected, and therefore likely to be the oldest region. Domain IV and Domain II are extensively interconnected with both themselves and Domain V. A portion of Domain IV is also extensively connected with the 30S subunit and hence Domain IV may be older than Domain II. These results are consistent with other evidence relating to the relative age of RNA regions. Although the relative time of addition of the GTPase center can not be reliably deduced it is pointed out that the development of this may have dramatically affected the progenotes that preceded the last common ancestor.

  6. Microscopic Origin of the Logarithmic Time Evolution of Aging Processes in Complex Systems

    NASA Astrophysics Data System (ADS)

    Lomholt, Michael A.; Lizana, Ludvig; Metzler, Ralf; Ambjörnsson, Tobias

    2013-05-01

    There exists compelling experimental evidence in numerous systems for logarithmically slow time evolution, yet its full theoretical understanding remains elusive. We here introduce and study a generic transition process in complex systems, based on nonrenewal, aging waiting times. Each state n of the system follows a local clock initiated at t=0. The random time τ between clock ticks follows the waiting time density ψ(τ). Transitions between states occur only at local clock ticks and are hence triggered by the local forward waiting time, rather than by ψ(τ). For power-law forms ψ(τ)≃τ-1-α (0<α<1) we obtain a logarithmic time evolution of the state number ⟨n(t)⟩≃log⁡(t/t0), while for α>2 the process becomes normal in the sense that ⟨n(t)⟩≃t. In the intermediate range 1<α<2 we find the power-law growth ⟨n(t)⟩≃tα-1. Our model provides a universal description for transition dynamics between aging and nonaging states.

  7. Microscopic origin of the logarithmic time evolution of aging processes in complex systems.

    PubMed

    Lomholt, Michael A; Lizana, Ludvig; Metzler, Ralf; Ambjörnsson, Tobias

    2013-05-17

    There exists compelling experimental evidence in numerous systems for logarithmically slow time evolution, yet its full theoretical understanding remains elusive. We here introduce and study a generic transition process in complex systems, based on nonrenewal, aging waiting times. Each state n of the system follows a local clock initiated at t = 0. The random time τ between clock ticks follows the waiting time density ψ(τ). Transitions between states occur only at local clock ticks and are hence triggered by the local forward waiting time, rather than by ψ(τ). For power-law forms ψ(τ) ≃ τ(-1-α) (0 < α < 1) we obtain a logarithmic time evolution of the state number ⟨n(t)⟩ ≃ log(t/t(0)), while for α > 2 the process becomes normal in the sense that ⟨n(t)⟩ ≃ t. In the intermediate range 1 < α < 2 we find the power-law growth ⟨n(t)⟩ ≃ t(α-1). Our model provides a universal description for transition dynamics between aging and nonaging states. PMID:25167457

  8. Trends and correlates of age at menarche in Colombia: Results from a nationally representative survey.

    PubMed

    Jansen, Erica C; Herrán, Oscar F; Villamor, Eduardo

    2015-12-01

    Surveillance of age at menarche could provide useful information on the impact of changing environmental conditions on child health. Nevertheless, nationally representative data are exceedingly rare. The aim of this study was to examine trends and sociodemographic correlates of age at menarche of Colombian girls. The study sample included 15,441 girls born between 1992 and 2000 who participated in the Colombian National Nutrition Survey of 2010. We estimated median menarcheal age using Kaplan-Meier time-to-event analyses. Hazard ratios with 95% confidence intervals were estimated with Cox regression models. The median age at menarche was 12.6 years. There was an estimated decline of 0.54 years/decade (P<0.001) over the birth years; this decline was only observed among girls from urban areas, and was more pronounced among girls from wealthier versus poorer families. Child height and BMI, maternal BMI and education, and family wealth were each inversely associated with menarcheal age whereas food insecurity and number of children in the household were positively associated with age at menarche. In conclusion, a negative trend in age at menarche is ongoing in Colombia, especially in groups most likely to benefit from socioeconomic development. PMID:26398849

  9. Developmental Origin of Oligodendrocyte Lineage Cells Determines Response to Demyelination and Susceptibility to Age-Associated Functional Decline

    PubMed Central

    Crawford, Abbe H.; Tripathi, Richa B.; Richardson, William D.; Franklin, Robin J.M.

    2016-01-01

    Summary Oligodendrocyte progenitors (OPs) arise from distinct ventral and dorsal domains within the ventricular germinal zones of the embryonic CNS. The functional significance, if any, of these different populations is not known. Using dual-color reporter mice to distinguish ventrally and dorsally derived OPs, we show that, in response to focal demyelination of the young adult spinal cord or corpus callosum, dorsally derived OPs undergo enhanced proliferation, recruitment, and differentiation as compared with their ventral counterparts, making a proportionally larger contribution to remyelination. However, with increasing age (up to 13 months), the dorsally derived OPs become less able to differentiate into mature oligodendrocytes. Comparison of dorsally and ventrally derived OPs in culture revealed inherent differences in their migration and differentiation capacities. Therefore, the responsiveness of OPs to demyelination, their contribution to remyelination, and their susceptibility to age-associated functional decline are markedly dependent on their developmental site of origin in the developing neural tube. PMID:27149850

  10. Age and geochemistry of the oceanic Manihiki Plateau, SW Pacific: New evidence for a plume origin

    NASA Astrophysics Data System (ADS)

    Timm, Christian; Hoernle, Kaj; Werner, Reinhard; Hauff, Folkmar; den Bogaard, Paul van; Michael, Peter; Coffin, Millard F.; Koppers, Anthony

    2011-04-01

    We present 40Ar/ 39Ar age and geochemical (major and trace element and Sr-Nd-Hf-Pb isotope) data from submarine samples recovered from the basement of the Manihiki Plateau during the R/V Sonne research expedition SO193. The samples, predominately tholeiites, with minor occurrences of basaltic andesites and hawaiites, give a mean age of 124.6 ± 1.6 Ma from four different localities on the plateau. Based on TiO 2 content, we define two groups of volcanic rocks that differ in trace element and isotopic compositions. Partial melting modeling suggests that the low-Ti group lavas were derived through large degrees of melting (c. 30%) of a peridotitic source at mantle potential melting temperatures of c. T p = 1510 °C, more than 100 °C above the ambient mantle potential melting temperature. Since the primary water contents of both groups of lavas are low (0.1-0.3g wt.%) and the source is peridotitic, excess temperature is most likely the reason for the large degrees of melting producing the large volume of plateau basalts, consistent with the involvement of a mantle plume. The incompatible element contents of the low-Ti group lavas show a multistage history with enrichment in the most incompatible elements of a previously highly depleted source. They have isotopic compositions similar to enriched mid-ocean-ridge basalt (EMORB) and similar to the common focal zone (FOZO) component. The high-Ti group lavas have more enriched incompatible element compositions overall. Their isotopic compositions tend towards an enriched mantle (EMI)-type endmember, similar, although less extreme, than lavas from the Pitcairn Islands. The geochemistry of the Manihiki Plateau can best be explained by a plume containing three components: 1) a dominant peridotitic FOZO-type component, 2) delaminated EMI-type subcontinental lithospheric mantle (SCLM), and 3) a HIMU (recycled oceanic crustal)-type component possibly in the form of eclogite/pyroxenite. The similarity in age and geochemical

  11. Carry A. Nation: "The Famous and Original Bar Room Smasher" Curriculum Packet.

    ERIC Educational Resources Information Center

    Kansas State Historical Society, Topeka.

    Carry Nation's personality, religious beliefs, and marriages to Charles Gloyd and, after his death, to David Nation all formed her into the reformer for which she became known. Carry Nation was involved in a variety of reform causes including prohibition, anti-smoking, women's health, and suffrage. Her prohibition reform efforts took place after…

  12. Health Disparities Grants Funded by National Institute on Aging: Trends between 2000 and 2010

    ERIC Educational Resources Information Center

    Kim, Giyeon; DeCoster, Jamie; Huang, Chao-Hui; Parmelee, Patricia

    2012-01-01

    Purpose of the Study: The present study examined the characteristics of health disparities grants funded by National Institute on Aging (NIA) from 2000 to 2010. Objectives were (a) to examine longitudinal trends in health disparities-related grants funded by NIA and (b) to identify moderators of these trends. Design and Methods: Our primary data…

  13. 78 FR 66015 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-04

    ... Committee: National Institute on Aging Special Emphasis Panel; Drug Development for Alzheimer's Disease... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  14. 77 FR 26770 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-07

    ... Committee: National Institute on Aging Special Emphasis Panel; Presenilin and Alzheimer's Disease. Date... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  15. 76 FR 28236 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-16

    ... Committee: National Institute on Aging Special Emphasis Panel, Pathology of Alzheimer's Disease. Date: June... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  16. 76 FR 1625 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-11

    ... Committee: National Institute on Aging Special Emphasis Panel; Drug Development for Alzheimer's Disease 2011... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  17. 76 FR 19105 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-06

    ... Committee: National Institute on Aging Special Emphasis Panel; Pathobiology of Alzheimer's Disease. Date... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  18. 77 FR 29677 - National Institute on Aging Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    ....gov . Name of Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's Disease Study... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  19. 78 FR 62639 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-22

    ... of Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's Disease Research... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  20. The Third National Health and Nutrition Examination Survey: Contributing Data on Aging and Health.

    ERIC Educational Resources Information Center

    Burt, Vicki L.; Harris, Tamara

    1994-01-01

    Describes third National Health and Nutrition Examination Survey (NHANES III), noting that upper age limit was removed and that older black, Mexican American, and white populations were oversampled. Sees NHANES III component for older adults providing multidimensional overview of physical and functional health status (osteoporosis; arthritis;…

  1. National Security in the Nuclear Age. A Proposed Booklist and Public Education Ideas for Libraries.

    ERIC Educational Resources Information Center

    Dane, Ernest B.

    A bibliography on national security in the nuclear age is divided into three sections. The first section describes a proposal calling for the compilation of a balanced and up-to-date collection of books and other materials on this issue to be included in all U.S. public libraries. Also discussed are selection criteria for the book list, project…

  2. The National Treatment Improvement Evaluation Study (NTIES): Profile of Clients Age 45 and Over.

    ERIC Educational Resources Information Center

    Caliber Associates, Fairfax, VA.

    This paper summarizes similarities and differences between two cohorts of the National Treatment Improvement Evaluation Study (NTIES) clients, those age 45 or older and those younger than 45. Results reveal the following: Clients in the 45+ cohort were considerably more likely to be treated for problems with alcohol or with heroin, and they were…

  3. Morphology, petrography, age and origin of Fogo Seamount chain, offshore eastern Canada

    NASA Astrophysics Data System (ADS)

    Pe-Piper, G.; de Jonge, A.; Piper, D. J. W.; Jansa, L. F.

    2003-04-01

    The Fogo Seamounts are located approximately 500 km offshore from Newfoundland to the southwest of the Grand Banks of Newfoundland. This complex seamount chain is early Cretaceous in age and is partially buried under later continental slope deposits. It has in the past been ascribed to the passage of a Canary or Azores hot spot. The seamounts are developed along the northeastern transform margin of the Jurassic central Atlantic Ocean. The Narwhal F-99 well was drilled in 1986 on the continental slope into one buried seamount. In this study, we bring together unpublished data on the bathymetry, seismic-reflection character, and distribution of the Fogo Seamounts and interpret new petrographic, geochemical, isotopic and geochronological data from a dredge sample from the central part of the seamount chain and from the Narwhal F-99 well, making comparisons with other offshore volcanic rocks on the eastern Canadian margin. Petrographically, the seamount samples consist of vitrophyric basalt, with clinopyroxene at Narwhal and kaersutite in the dredge sample. Chemically, the samples are olivine basalt with a low Mg number and low concentration of transition metals. Trace element and REE abundances are similar to those of other early Cretaceous volcanic rocks on the southeast Canadian margin. Three petrogenetic types of mafic magma are recognised in the area. The dredge sample is typical OIB rather alkalic basalts and similar to those in other seamount chains. Rocks at Narwhal and Brant have a greater signature of a depleted mantle source (are more tholeiitic). All have Nd isotopes similar to the Newfoundland and New England seamounts. In Orpheus graben to the northwest, there appears to have been greater crustal contamination, either from the crust in the region or from mantle previously enriched in crustal contaminants. The dredge sample gave a 40Ar/39Ar age of 130.3 +/- 1.3 Ma (Hauterivian). A K/Ar age from the Narwhal F-99 well of 127 +/- 6 Ma is inconsistent with

  4. Global signatures and dynamical origins of the Little Ice Age and Medieval Climate Anomaly.

    PubMed

    Mann, Michael E; Zhang, Zhihua; Rutherford, Scott; Bradley, Raymond S; Hughes, Malcolm K; Shindell, Drew; Ammann, Caspar; Faluvegi, Greg; Ni, Fenbiao

    2009-11-27

    Global temperatures are known to have varied over the past 1500 years, but the spatial patterns have remained poorly defined. We used a global climate proxy network to reconstruct surface temperature patterns over this interval. The Medieval period is found to display warmth that matches or exceeds that of the past decade in some regions, but which falls well below recent levels globally. This period is marked by a tendency for La Niña-like conditions in the tropical Pacific. The coldest temperatures of the Little Ice Age are observed over the interval 1400 to 1700 C.E., with greatest cooling over the extratropical Northern Hemisphere continents. The patterns of temperature change imply dynamical responses of climate to natural radiative forcing changes involving El Niño and the North Atlantic Oscillation-Arctic Oscillation. PMID:19965474

  5. The origins of pure and applied science in Gilded Age America.

    PubMed

    Lucier, Paul

    2012-09-01

    "Pure science" and "applied science" have peculiar histories in the United States. Both terms were in use in the early part of the nineteenth century, but it was only in the last decades that they took on new meanings and became commonplace in the discourse of American scientists. The rise in their currency reflected an acute concern about the corruption of character and the real possibilities of commercializing scientific knowledge. "Pure" was the preference of scientists who wanted to emphasize their nonpecuniary motives and their distance from the marketplace. "Applied" was the choice of scientists who accepted patents and profits as other possible returns on their research. In general, the frequent conjoining of "pure" and "applied" bespoke the inseparable relations of science and capitalism in the Gilded Age. PMID:23286191

  6. The age and origin of the "Younger Dryas climate event" in Greenland ice cores

    NASA Astrophysics Data System (ADS)

    Fairbanks, R. G.; Bard, E.

    1990-12-01

    230Th/234U and 14C dating of Barbados corals has extended the calibration of 14C years B.P. to calendar years B.P. beyond the 9200 year tree ring series (Bard et al., 1990). This now permits the conversion of 14C chronozones, which delimit major climate shifts in western Europe, to calendar years. The Younger Dryas chronozone, defined as 11,000 to 10,000 14C years B.P., corresponds to 13,000 to 11,700 calendar years B.P. This calibration affects the interpretation of an intensely studied example of the "Younger Dryas climate event," the δ18O anomaly between 1785 and 1793 m in Dye 3 ice core. The end of the δ18O anomaly in Dye 3 ice core has been dated by measurements of 14C in air bubbles (Andree et al., 1984, 1986) and by annual layer counting (Hammer et al., 1986). The older 14C dates fall out of the range of the tree ring calibration series but can now be calibrated to calendar years using the Barbados 230Th/234U calibration. The 14Ccorrected age for the end of the δ18O event is 10,300 ± 400 calendar years B.P. compared to the annual layer counting age of 10,720 ± 150 years B.P. Thus, the "Younger Dryas" event in the Dye 3 ice core ends in the Preboreal chronozone (11,700 to 10,000 calendar years B.P.) and is not correlative with the end of the Younger Dryas event identified in pollen records marking European vegetation changes. The end of the Dye 3 δ18O event is, however, correlative with the end of meltwater pulse IB (Fairbanks, 1989), marking a period of intense deglaciation with meltwater discharge rates exceeding 13,000 km³/yr.

  7. The Origin and Age of Scallop Floodplain Benches from Difficult Run, Fairfax County, Virginia.

    NASA Astrophysics Data System (ADS)

    Scamardo, J. E.; Pizzuto, J. E.; Skalak, K.; Benthem, A.

    2015-12-01

    Sediment is deposited within scallop-shaped erosional scarps that form between trees armoring the banks of Difficult Run, a suburban watershed with a forested riparian zone. These deposits create small (surface area 85 m2, volume 300 m3), low-lying floodplain landforms this group terms Scallop Floodplain Benches (SFB). It is hypothesized that SFB formed within the past couple decades initially forming as transversal accretion deposits and eventually gaining floodplain features dominated by vertical accretion. Stratigraphic data supports that SFB deposits begin laterally as sand and gravel bars approximately 100 cm thick, and continue to grow by vertical accretion of sand, silt, and clay. As a SFB reaches its maximum height, a distinctive levee develops adjacent to the channel, and fine-grained silt and clay are deposited behind the levee. Core samples to a depth of 118 cm and additional samples from an overbank event that occurred on June 20, 2015 were collected from one of two SFB on Difficult Run near Leesburg Pike. The grain size distribution was measured using a Coulter Counter and activities of Pb-210, Cs-137, and Be-7 were measured using High Purity Germanium Detectors. Cs-137 activities are relatively constant with depth without a well-defined peak, suggesting that the SFB was deposited after 1963. Be-7 is present in the recent flood deposits, but is absent below the surface, suggesting that the SFB deposits are at least several years old. Excess Pb-210 activities decrease exponentially with depth, and can be fit using the Constant Rate of Supply method to determine an average age of approximately 13.5 years for the SFB. The SFB is storing sediment at a rate of 27 tons/year, which is equal to 0.35% of the annual sediment load of Difficult Run, based on this average age. SFB appear to be a significant component of the sediment storage of Difficult Run and therefore should be considered in the sediment budget.

  8. Age and origin of cold climate landforms from the Eastern Cape Drakensberg, southern Africa: palaeoclimatic implications

    NASA Astrophysics Data System (ADS)

    Mills, Stephanie C.; Barrows, Timothy T.; Fifield, L. Keith

    2014-05-01

    Reliable dating is crucial for resolving the nature and timing of cold events in southern Africa and the associated cold climate landforms produced. Evidence for glaciation has been proposed for the Eastern Cape Drakensberg, based on the identification of moraines that were presumed to be of last glacial maximum age. Temperature depressions of 10-17°C have been proposed for this region, based on the presence of these moraines (Lewis and Illgner, 2001) and the identification of a relict rock glacier. Such large temperature depressions are, however, unsupported by other palaeoclimatic proxies in southern Africa. Debate regarding the occurrence of glaciation in southern Africa has been ongoing for several decades. There is good evidence for small-scale glaciation during the last glacial cycle in Lesotho, at elevations exceeding 3000 m a.s.l., but these sites are more than 1000 m higher in elevation than those identified in the Eastern Cape, and suggest a temperature depression of only ~6°C and a change to a winter dominated precipitation regime during the last glacial cycle. This paper presents preliminary cosmogenic nuclide exposure ages for the Eastern Cape 'moraines' and a periglacial blockstream in this region. We discuss potential alternative interpretations for the formation of the landforms and suggest that glaciers were absent in the Eastern Cape Drakensberg during the last glacial period. However, there is widespread evidence for periglacial activity down to an elevation of ~1700 m a.s.l., as illustrated by extensive blockstreams, stone garlands and solifluction deposits. These periglacial deposits suggest that the climate was much colder (~6ºC) during the last glacial cycle, in keeping with other proxy records, but not cold enough to initiate or sustain glaciers at low elevations. References Lewis C. A., Illgner, P. M., 2001. Late Quaternary glaciation in Southern Africa: moraine ridges and glacial deposits at Mount Enterprise in the Drakensberg of the

  9. National and Post-National Discourses and the Construction of Linguistic Identities by Students of Albanian Origin in Greece

    ERIC Educational Resources Information Center

    Archakis, Argiris

    2016-01-01

    Drawing on Critical Discourse Analysis and, more specifically, on the relationship between the macro-level of dominant discourses and the micro-level of individual positionings, we examine the way linguistic identities are constructed by immigrant students of Albanian origin in Greece. We elaborate on two "competitive" discourses: the…

  10. Early-life origins of chronic respiratory diseases: understanding and promoting healthy ageing.

    PubMed

    Carraro, Silvia; Scheltema, Nienke; Bont, Louis; Baraldi, Eugenio

    2014-12-01

    Chronic obstructive respiratory disorders such as asthma and chronic obstructive pulmonary disease often originate early in life. In addition to a genetic predisposition, prenatal and early-life environmental exposures have a persistent impact on respiratory health. Acting during a critical phase of lung development, these factors may change lung structure and metabolism, and may induce maladaptive responses to harmful agents, which will affect the whole lifespan. Some environmental factors, such as exposure to cigarette smoke, type of childbirth and diet, may be modifiable, but it is more difficult to influence other factors, such as preterm birth and early exposure to viruses or allergens. Here, we bring together recent literature to analyse the critical aspects involved in the early stages of lung development, going back to prenatal and perinatal events, and we discuss the mechanisms by which noxious factors encountered early on may have a lifelong impact on respiratory health. We briefly comment on the need for early disease biomarkers and on the possible role of "-omic" technologies in identifying risk profiles predictive of chronic respiratory conditions. Such profiles could guide the ideation of effective preventive strategies and/or targeted early lifestyle or therapeutic interventions. PMID:25323240

  11. Magnetic Signature of the Lunar South Pole-Aitken Basin: Character, Origin, and Age

    NASA Technical Reports Server (NTRS)

    Purucker, Michael E.; Head, James W., III; Wilson, Lionel

    2012-01-01

    A new magnetic map of the Moon, based on Lunar Prospector (LP) magnetometer observations, sheds light on the origin of the South Pole-Aitken Basin (SPA), the largest and oldest of the recognized lunar basins. A set of WNW-trending linear to arcuate magnetic features, evident in both the radial and scalar observations, covers much of a 1000 km wide region centered on the NW portion of SPA. The source bodies are not at the surface because the magnetic features show no first-order correspondence to any surface topographic or structural feature. Patchy mare basalts of possible late Imbrianage are emplaced within SPA and are inferred to have been emplaced through dikes, directly from mantle sources. We infer that the magnetic features represent dike swarms that served as feeders for these mare basalts, as evident from the location of the Thomson/ Mare Ingenii, Van de Graaff, and Leeuwenhoek mare basalts on the two largest magnetic features in the region. Modeling suggests that the dike zone is between 25 and 50 km wide at the surface, and dike magnetization contrasts are in the range of 0.2 A/m. We theorize that the basaltic dikes were emplaced in the lunar crust when a long-lived dynamo was active. Based on pressure, temperature, and stress conditions prevalent in the lunar crust, dikes are expected to be a dominantly subsurface phenomenon, consistent with the observations reported here.

  12. A service life extension (SLEP) approach to operating aging aircraft beyond their original design lives

    NASA Astrophysics Data System (ADS)

    Pentz, Alan Carter

    With today's uncertain funding climate (including sequestration and continuing budget resolutions), decision makers face severe budgetary challenges to maintain dominance through all aspects of the Department of Defense (DoD). To meet war-fighting capabilities, the DoD continues to extend aircraft programs beyond their design service lives by up to ten years, and occasionally much more. The budget requires a new approach to traditional extension strategies (i.e., reuse, reset, and reclamation) for structural hardware. While extending service life without careful controls can present a safety concern, future operations planning does not consider how much risk is present when operating within sound structural principles. Traditional structural hardware extension methods drive increased costs. Decision makers often overlook the inherent damage tolerance and fatigue capability of structural components and rely on simple time- and flight-based cycle accumulation when determining aircraft retirement lives. This study demonstrates that decision makers should consider risk in addition to the current extension strategies. Through an evaluation of eight military aircraft programs and the application and simulation of F-18 turbine engine usage data, this dissertation shows that insight into actual aircraft mission data, consideration of fatigue capability, and service extension length are key factors to consider. Aircraft structural components, as well as many critical safety components and system designs, have a predefined level of conservatism and inherent damage tolerance. The methods applied in this study would apply to extensions of other critical structures such as bridges. Understanding how much damage tolerance is built into the design compared to the original design usage requirements presents the opportunity to manage systems based on risk. The study presents the sensitivity of these factors and recommends avenues for further research.

  13. The age and origin of felsic intrusions of the Thetford Mines ophiolite, Quebec.

    USGS Publications Warehouse

    Clague, D.A.; Frankel, C.S.; Eaby, J.S.

    1985-01-01

    This ophiolite was obducted in the early Ordovician during the closing of the proto-Atlantic. The tectonized peridotite of the lower unit of the ophiolite is intruded by felsic dykes and pods, including isolated lenses of massive rodingite, small bodies of strongly deformed diorite, and younger, less deformed monzonite. These intrusions are found only near the base of the ophiolite, and are considered to have been emplaced before the ophiolite reached its present position. The young group of intrusions consists of biotite-muscovite quartz monzonite and leuco-quartz monzonite. Analysed samples have high K2O, high (K2O X 100)/Na2O + K2O) ratios, and high initial Sr ratios, indicating that the magma source was continental and that these felsic rocks formed by partial melting of continental sediments. Whole-rock and mineral isochron ages suggest that the felsic intrusions are approx 456 + or - 4 m.y. old and that they were metamorphosed approx 418 + or - 7 m.y. ago. The detachment of the ophiolite occurred approx 491 + or - 3 m.y. ago. The felsic dykes were intruded approx 35 m.y. later, during the Taconic orogeny. The lengthy time between detachment and final nappe emplacement recorded by the felsic dykes may be a requirement for formation of abundant asbestiform chrysotile. Whole-rock analyses (16) and Rb, Sr and 87Sr/86Sr data from the Colline de Granite, King Mts., Vimy Ridge and Black Lake samples are presented.-P.Br.

  14. The active site of oxidative phosphorylation and the origin of hyperhomocysteinemia in aging and dementia.

    PubMed

    McCully, Kilmer S

    2015-01-01

    The active site of oxidative phosphorylation and adenosine triphosphate (ATP) synthesis in mitochondria is proposed to consist of two molecules of thioretinamide bound to cobalamin, forming thioretinaco, complexed with ozone, oxygen, nicotinamide adenine dinucleotide. and inorganic phosphate, TR2CoO3O2NAD(+)H2PO4(-). Reduction of the pyridinium nitrogen of the nicotinamide group by an electron from electron transport complexes initiates polymerization of phosphate with adenosine diphosphate, yielding nicotinamide riboside and ATP bound to thioretinaco ozonide oxygen. A second electron reduces oxygen to hydroperoxyl radical, releasing ATP from the active site. A proton gradient is created within F1F0 ATPase complexes of mitochondria by reaction of protons with reduced nicotinamide riboside and with hydroperoxyl radical, yielding reduced nicotinamide riboside and hydroperoxide. The hyperhomocysteinemia of aging and dementia is attributed to decreased synthesis of adenosyl methionine by thioretinaco ozonide and ATP, causing decreased allosteric activation of cystathionine synthase and decreased allosteric inhibition of methylenetetrahydrofolate reductase and resulting in dysregulation of methionine metabolism. PMID:25887881

  15. Using and Interpreting Mental Health Measures in the National Social Life, Health, and Aging Project

    PubMed Central

    Payne, Carolyn; Hedberg, E. C.; Kozloski, Michael; Dale, William

    2014-01-01

    Introduction. National Social Life, Health, and Aging Project (NSHAP) included five unique mental health measures in Waves 1 and 2 that researchers can use to measure the overall emotional health of participants: depressive symptoms, happiness–unhappiness, anxiety symptoms, perceived stress, and felt loneliness. For each, we detail the rationale for its development and explain how to score, analyze, and interpret results. Method. NSHAP developed its measures by modifying traditional short-form scales to improve response efficiency and reduce respondent burden. Scoring protocols and interpretations were developed for each measure. U.S. population estimates for older adults born between 1920 and 1947 were generated using age-eligible samples from Waves 1 and 2. Results. NSHAP’s protocols yielded U.S. prevalence rates similar to other nationally representative studies of older adults and comparable between waves. Higher estimates of anxiety symptoms and perceived stress in Wave 2 compared with Wave 1 were explained by age, administration mode, and time period. Analytic strategies for longitudinal analyses are provided. In Wave 2, mental health generally was worse at older ages, with women having more symptoms at younger ages than men. Women had fewer anxiety symptoms at the oldest ages. Discussion. NSHAP’s mental health measures were successfully integrated into the project’s survey and showed acceptable external reliability as well as moderately stable individual characteristics across the 5 years between Waves 1 and 2. Depressive symptoms and unhappiness may form a mental health cluster in the elderly, distinct from anxiety symptoms, perceived stress, and felt loneliness. Gender differences in age-specific patterns of mental health were evident using the exact age of participants rather than the traditional decade groupings. Administration mode and time period (between 2005–2006 and 2010–2011) were determined to be potential confounds that need to be

  16. Paternal Age and Offspring Congenital Heart Defects: A National Cohort Study

    PubMed Central

    Huang, Guo Ying; Olsen, Jørn; Li, Jiong

    2015-01-01

    Paternal age has been associated with offspring congenital heart defects (CHDs), which might be caused by increased mutations in the germ cell line because of cumulated cell replications. Empirical evidences, however, remain inconclusive. Furthermore, it is unknown whether all subtypes of CHDs are affected by paternal age. We aimed to explore the relationship between paternal age and the risk of offspring CHDs and its five common subtypes using national register data in Denmark. A total of 1 893 899 singletons born in Denmark from 1977 to 2008 were included in this national-based cohort study. Cox’s proportion hazards model with robust sandwich estimate option was used to estimate the hazards ratio (95% confidence interval) for the associations between paternal age and all CHDs, as well as subtypes of CHDs (patent ductus arteriosus (PDA), ventricular septal defect (VSD), atrial septal defect (ASD), tetralogy of fallot (TOF) and coarctation of the aorta (CoA)). We did not observe an overall association between paternal age and offspring CHDs. However, compared to the paternal age of 25–29 years, paternal age of older than 45 years was associated with a 69% increased risk of PDA (HR45+ = 1.69, 95%CI:1.17–2.43). We observed similar results when subanalyses were restricted to children born to mothers of 27–30 years old. After taking into consideration of maternal age, our data suggested that advanced paternal age was associated with an increased prevalence of one subtype of offspring congenital heart defects (CHDs), namely patent ductus arteriosus (PDA). PMID:25806788

  17. Sensory Function: Insights From Wave 2 of the National Social Life, Health, and Aging Project

    PubMed Central

    Kern, David W.; Wroblewski, Kristen E.; Chen, Rachel C.; Schumm, L. Philip; McClintock, Martha K.

    2014-01-01

    Objectives. Sensory function, a critical component of quality of life, generally declines with age and influences health, physical activity, and social function. Sensory measures collected in Wave 2 of the National Social Life, Health, and Aging Project (NSHAP) survey focused on the personal impact of sensory function in the home environment and included: subjective assessment of vision, hearing, and touch, information on relevant home conditions and social sequelae as well as an improved objective assessment of odor detection. Method. Summary data were generated for each sensory category, stratified by age (62–90 years of age) and gender, with a focus on function in the home setting and the social consequences of sensory decrements in each modality. Results. Among both men and women, older age was associated with self-reported impairment of vision, hearing, and pleasantness of light touch. Compared with women, men reported significantly worse hearing and found light touch less appealing. There were no gender differences for vision. Overall, hearing loss seemed to have a greater impact on social function than did visual impairment. Discussion. Sensory function declines across age groups, with notable gender differences for hearing and light touch. Further analysis of sensory measures from NSHAP Wave 2 may provide important information on how sensory declines are related to health, social function, quality of life, morbidity, and mortality in this nationally representative sample of older adults. PMID:25360015

  18. Origin and age of the earliest Martian crust from meteorite NWA 7533.

    PubMed

    Humayun, M; Nemchin, A; Zanda, B; Hewins, R H; Grange, M; Kennedy, A; Lorand, J-P; Göpel, C; Fieni, C; Pont, S; Deldicque, D

    2013-11-28

    The ancient cratered terrain of the southern highlands of Mars is thought to hold clues to the planet's early differentiation, but until now no meteoritic regolith breccias have been recovered from Mars. Here we show that the meteorite Northwest Africa (NWA) 7533 (paired with meteorite NWA 7034) is a polymict breccia consisting of a fine-grained interclast matrix containing clasts of igneous-textured rocks and fine-grained clast-laden impact melt rocks. High abundances of meteoritic siderophiles (for example nickel and iridium) found throughout the rock reach a level in the fine-grained portions equivalent to 5 per cent CI chondritic input, which is comparable to the highest levels found in lunar breccias. Furthermore, analyses of three leucocratic monzonite clasts show a correlation between nickel, iridium and magnesium consistent with differentiation from impact melts. Compositionally, all the fine-grained material is alkalic basalt, chemically identical (except for sulphur, chlorine and zinc) to soils from Gusev crater. Thus, we propose that NWA 7533 is a Martian regolith breccia. It contains zircons for which we measured an age of 4,428 ± 25 million years, which were later disturbed 1,712 ± 85 million years ago. This evidence for early crustal differentiation implies that the Martian crust, and its volatile inventory, formed in about the first 100 million years of Martian history, coeval with earliest crust formation on the Moon and the Earth. In addition, incompatible element abundances in clast-laden impact melt rocks and interclast matrix provide a geochemical estimate of the average thickness of the Martian crust (50 kilometres) comparable to that estimated geophysically. PMID:24256724

  19. Origin and K/Ar age of cryptomelane-bearing Sn placers on silcretes, SE Germany

    NASA Astrophysics Data System (ADS)

    Dill, H. G.; Wemmer, K.

    2012-11-01

    During the early Miocene (Aquitanian-Burdigalian) an alluvial-fluvial drainage system evolved along the boundary fault of the Münchberg Gneiss Complex in SE Germany. The resultant NE-SW trending channel system collected debris from the enclosing Paleozoic country rocks and from gossans of cassiterite-bearing veins exposed to denudation in the roof rocks of the adjacent Late Variscan Sparnberg-Pottiga Granite. Three different types of placer minerals occur: (1) isolated grains of cassiterite, (2) armored relics of cassiterite and barite, (3) remobilized and redeposited silica aggregates. Silica is present in a zone of silcretes, in mechanically redeposited pebbles within this depression and in cobbles of quartz gangue derived from the nearby vein-type deposits. These silcretes developed from alkaline fluids and were redeposited under semiarid conditions with dryer (period of solution) and wetter seasons (period of redeposition) at ≥ 23 Ma. Cryptomelane I formed under dry conditions around 23 Ma when the pore space of the channel lag deposits was incompletely filled with water, whereas goethite points to more humid climatic conditions between 23 and 17 Ma as the fluids were more acidic. Cryptomelane II filled the pore space of the clastic sediments to completeness on increasing humidity at ≤ 17 Ma. The mineral association under study pertains to the group of supergene Fe-Mn deposits (Hunsrück-type) whose ore-forming processes span a wide range from pedological/ground water-related Fe-Mn concentration in hydromorphic soils to alluvial-fluvial pebble or placer-type concentrations. The current investigations involved geological mapping and geoelectrical DC deep sounding in the field and optical microscopy, SEM-EDX, and K/Ar age dating of cryptomelane in the laboratory.

  20. Origin and age of the Eisenkappel gabbro to granite suite (Carinthia, SE Austrian Alps)

    PubMed Central

    Miller, C.; Thöni, M.; Goessler, W.; Tessadri, R.

    2011-01-01

    The northern part of the Karawanken plutonic belt is a gabbro–granite complex located just north of the Periadriatic lineament near the Slovenian–Austrian border. Petrographic and geochemical studies of the Eisenkappel intrusive complex indicate that this multiphase plutonic suite developed by a combination of crystal accumulation, fractional crystallization and assimilation processes, magma mixing and mingling. The mafic rocks are alkaline and have within-plate geochemical characteristics, indicating anorogenic magmatism in an extensional setting and derivation from an enriched mantle source. The mafic melts triggered partial melting of the crust and the formation of granite. The granitic rocks are alkalic, metaluminous and have the high Fe/Fe + Mg characteristics of within-plate plutons. Temperature and pressure conditions, derived from amphibole-plagioclase and different amphibole thermobarometers, suggest that the analysed Eisenkappel gabbros crystallized at around 1000 ± 20 °C and 380–470 MPa, whereas the granitic rock crystallized at T ≤ 800 ± 20 °C and ≤ 350 MPa. Mineral-whole rock Sm–Nd analyses of two cumulate gabbros yielded 249 ± 8.4 Ma and 250 ± 26 Ma (εNd: + 3.6), garnet-whole rock Sm–Nd analyses of two silicic samples yielded well-constrained ages of 238.4 ± 1.9 Ma and 242.1 ± 2.1 Ma (εNd: − 2.6). PMID:26525511

  1. Origin and age of the earliest Martian crust from meteorite NWA 7533

    NASA Astrophysics Data System (ADS)

    Humayun, M.; Nemchin, A.; Zanda, B.; Hewins, R. H.; Grange, M.; Kennedy, A.; Lorand, J.-P.; Göpel, C.; Fieni, C.; Pont, S.; Deldicque, D.

    2013-11-01

    The ancient cratered terrain of the southern highlands of Mars is thought to hold clues to the planet's early differentiation, but until now no meteoritic regolith breccias have been recovered from Mars. Here we show that the meteorite Northwest Africa (NWA) 7533 (paired with meteorite NWA 7034) is a polymict breccia consisting of a fine-grained interclast matrix containing clasts of igneous-textured rocks and fine-grained clast-laden impact melt rocks. High abundances of meteoritic siderophiles (for example nickel and iridium) found throughout the rock reach a level in the fine-grained portions equivalent to 5 per cent CI chondritic input, which is comparable to the highest levels found in lunar breccias. Furthermore, analyses of three leucocratic monzonite clasts show a correlation between nickel, iridium and magnesium consistent with differentiation from impact melts. Compositionally, all the fine-grained material is alkalic basalt, chemically identical (except for sulphur, chlorine and zinc) to soils from Gusev crater. Thus, we propose that NWA 7533 is a Martian regolith breccia. It contains zircons for which we measured an age of 4,428 +/- 25 million years, which were later disturbed 1,712 +/- 85 million years ago. This evidence for early crustal differentiation implies that the Martian crust, and its volatile inventory, formed in about the first 100 million years of Martian history, coeval with earliest crust formation on the Moon and the Earth. In addition, incompatible element abundances in clast-laden impact melt rocks and interclast matrix provide a geochemical estimate of the average thickness of the Martian crust (50 kilometres) comparable to that estimated geophysically.

  2. Age constraints on late Mesozoic lithospheric extension and origin of bimodal volcanic rocks from the Hailar basin, NE China

    NASA Astrophysics Data System (ADS)

    Li, Shuang-Qing; Hegner, Ernst; Yang, Yi-Zeng; Wu, Jia-De; Chen, Fukun

    2014-03-01

    Following the amalgamation of the late Mesoproterozoic-Carboniferous Central Asian Orogenic Belt with the Siberian and North China cratons, NE China underwent late Mesozoic lithospheric extension and widespread formation of volcano-sedimentary basins. We report U-Pb zircon ages and geochemical data for mafic and felsic volcanic rocks from the Hailar basin, located about 1000 km north of Beijing. Zircon populations of six felsic rock samples analyzed by laser ablation ICP-MS yielded similar U-Pb age spectra ranging from 158 to 125 Ma. The youngest zircon ages are interpreted as time of magma eruption and the xenocrystic zircon-age spectra as evidence for a protracted melting of lower crust due to the underplating of mantle-derived magmas during lithospheric extension. The volcanic assemblage has a bimodal composition comprising geochemically evolved trachybasalts and felsic volcanic rocks of I- and subordinate A-type compositions. The mafic volcanic rocks have negative Nb-anomalies, high Th/Nb and Ce/Pb ratios, low initial ɛNd values of + 0.4 to + 3.4, and radiogenic Pb and Sr isotopes all interpreted as evidence for the melting of passively upwelling asthenosphere and lithospheric mantle previously modified by plate subduction. The xenocrystic zircon ages and chemical/isotopic data of the felsic rocks support an origin from juvenile crustal protoliths: the data of I-type felsic rocks are consistent with the melting of underplated mafic protoliths and those of the A-type rhyolites support the melting of a crustal source with a composition similar to the I-type felsites with apatite controlling their Nb anomaly. The evidence for the persistent melting of a subduction-modified mantle in NE China is in agreement with a model of an extending coupled upper mantle-crust system due to a retreating Paleo-Pacific trench.

  3. Establishing the European Research Area in Ageing: a network of national research programmes.

    PubMed

    Geyer, Gerda

    2005-10-01

    The following paper gives a summary of the European Commission's research policy with regard to the ERA-NET scheme and especially with regard to the ERA-AGE project that was launched in March 2004. All the partner institutions in the ERA-AGE project are main national funding agencies, research councils or ministries. Some selected examples of programme funding by the partner institutions may demonstrate their different ways of funding research and show the great variety of programmes. The long-term objective of the ERA-AGE project is to create a sustainable basis for the planning, implementation and exploitation of transnational research. In future, the European Research Area in Ageing could gain an added value from research investments by integrating existing funding mechanisms and research infrastructures, by commonly deciding on research priorities for funding activities in order to reduce fragmentation and duplication, and by the recruitment of young researchers. PMID:16154308

  4. Age and origin of Terra Rossa soils in the Coonawarra area of South Australia

    NASA Astrophysics Data System (ADS)

    Mee, Aija C.; Bestland, Erick A.; Spooner, Nigel A.

    2004-03-01

    The famous Terra Rossa soil in the Coonawarra area, South Australia, is dominated by locally derived aeolian detritus, which probably accumulated over the last 120-130 ka. Four soil profiles and associated limestone and lunette deposits were investigated using the following methods: mass balance geochemistry of bulk soil samples (major and trace elements), quantitative X-ray diffraction (XRD) mineralogy, strontium isotopes (87/86), as well as grain-size analysis and cation exchange capacity. These data show that the Terra Rossa soil from the Coonawarra has a thick, clayey B-horizon which is geochemically homogeneous and dominated by smectite and kaolinite. Mass-balance calculations show unrealistic weathering scenarios when plotted using silicate residuum from the underlying limestone as parent. Realistic weathering scenarios are produced with fine-grained silicate material from local lunette deposits as parent. Strontium isotopes of silicate residuum from Gambier Limestone (0.78) contrast strongly with the clayey B-horizon (0.726). Strontium isotope ratios of silicate material from a local lunette (0.725) are similar to the B-horizon soil values. Strontium isotope ratios from regional geological units indicate that the strontium signature in the lunette and soil B-horizon is dominated by weathering products from the Palaeozoic Kanmantoo shales, extensively exposed upwind to the west on Kangaroo Island and the Fleurieu Peninsula. Optical (optically stimulated luminescence, OSL) dating of 61 individual quartz grains (single aliquot) from three samples in the Coonawarra soil profile (one from the A-horizon and two from the B-horizon) shows that most of the quartz sand grains have been buried for only a few thousand years. Many of the grains, however, have been buried for tens of thousands of years with three grains having exposure ages of between 105 and 109 ka. The large population of young exposure dates represents quartz sands recently exposed in the A-horizon and

  5. Thermal and tectonic evolution of the central and southern Appalachians: evidence from distribution, age, and origin of granitic rocks

    SciTech Connect

    Sinha, A.K.; Guy, R.; Hund, E.; Tamburro, E.

    1985-01-01

    The distribution and resolution of thermal events and associated igneous activity can discriminate between tectonic processes that form orogenic terrains, i.e., accretion of terranes, overthrusting of terranes versus thrust stacking within terranes. Reinterpretation of regional tectonics (Higgins et al., 1984) coupled with the authors interpretation of the age, origin, and distribution of granitic rocks suggest a very different mechanism for the evolution of the central and southern Appalachian orogenic belt. The Cambro-Ordovician magmatic arc (weakly bimodal) separated from the North American Margin by a Back arc basin, was thrust over the North American plate margin during the middle Ordovician. The Avalon terrane (Little River allochthon of Higgins et al., 1984) arrived during the late Silurian - but unlike earlier models that require subduction zone related with its arrival, the authors postulate strike-slip tectonics. The gabbro-diorite-syenite association in the Charlotte belt (Macon melange of Higgins) is probably related to grabens associated with the strike-slip accretion. Rocks of similar age (Siluro-Devonian) in the present day Blue Ridge and Inner Piedmont blocks are related to decompressional melting after the Ordovician thrusting. The high pressure metamorphism and associated melting show a range in ages indicating variations in uplift rates or thickness of the crust caused by the initial overthrusting, and do not require a discrete subduction or orogenic event. The Permo-Carboniferous igneous activity, and associated uplift and thrusting with a strike-slip component are related to oblique subduction and post-subduction collision processes.

  6. Age and origin of the Lomonosov Ridge: a key continental fragment in Arctic Ocean reconstructions

    NASA Astrophysics Data System (ADS)

    Marcussen, Christian; Knudsen, Christian; Hopper, John R.; Funck, Thomas; Ineson, Jon R.; Bjerager, Morten

    2015-04-01

    The Lomonosov Ridge is a trans-oceanic seafloor high that separates the Eurasia Basin from the Amerasia Basin. It extends for a distance of almost 1800 km across the Arctic Ocean from the Lincoln Shelf off Greenland and Canada to the East Siberian Shelf. Although known from the ACEX drilling expedition to be a sliver of continental crust, it remains an enigmatic feature and many details of its history are unknown. In the summer of 2012, GEUS recovered dredge samples from two locations along the flank of the ridge facing the Eurasian Basin. The samples comprise 100 kg and 200 kg of rocks and rock pieces ranging in size from 0.1 to 80 kg which were recovered from two different scarps associated with rotated continental fault blocks. A significant quantity of rocks with identical structures and isotopic fingerprints show that they formed at the same time and from the same geological material. This combined with the broken and angular nature of many of the pieces recovered indicates that the material is from in situ bedrock and does not represent dropstones brought to the area by drifting ice. Two main sedimentary rock types were recovered - an arkosic metasedimentary rock, and a quartz rich non-metamorphic sandstone. The arkosic metasedimentary rock shows compositional layering (primary heterolithic fabric) that is deformed and with a well-developed schistosity. These metasedimentary rocks contain muscovite with textural evidence that shows the muscovite is metamorphic and not detrital, and thus formed at the time the rocks were deformed. The metamorphic fabrics and mineralogy indicate deformation under greenschist facies conditions, indicating that the metamorphism was associated with an orogenic event; the metamorphic muscovite has yielded an Ar/Ar age of around 470 Ma. Thus the rock is interpreted as a Proterozoic to lower Palaeozoic heterolithic sandstone that was involved in an orogenic event during the Ordovician. This event may be related to the Mid

  7. On the origin of brucellosis in bison of Yellowstone National Park: a review

    USGS Publications Warehouse

    Meagher, Mary; Meyer, Margaret E.

    1994-01-01

    Brucellosis caused by Brucella abortus occurs in the free-ranging bison (Bison bison) of Yellowstone and Wood Buffalo National Parks and in elk (Cervus elaphus) of the Greater Yellowstone Area. As a result of nationwide bovine brucellosis eradication programs, states and provinces proximate to the national parks are considered free of bovine brucellosis. Thus, increased attention has been focused on the wildlife within these areas as potential reservoirs for transmission to cattle. Because the national parks are mandated as natural areas, the question has been raised as to whether Brucella abortus is endogenous or exogenous to bison, particularly for Yellowstone National Park. We synthesized diverse lines of inquiry, including the evolutionary history of both bison and Brucella, wild animals as Brucella hosts, biochemical and genetic information, behavioral characteristics of host and organism, and area history to develop an evaluation of the question for the National Park Service. All lines of inquiry indicated that the organism was introduced to North America with cattle, and that the introduction into the Yellowstone bison probably was directly from cattle shortly before 1917. Fistulous withers of horses was a less likely possibility. Elk on winter feedgrounds south of Yellowstone National Park apparently acquired the disease directly from cattle. Bison presently using Grand Teton National Park probably acquired brucellosis from feedground elk.

  8. Constraining the age and origin of the seamount province in the Northeast Indian Ocean using geophysical techniques

    NASA Astrophysics Data System (ADS)

    Taneja, Rajat; O'Neill, Craig

    2014-12-01

    The breakup of western margin of Australia from Greater India started around 155 Ma and progressed southwards. After the separation, the interceding intraplate region experienced large volumes of submarine volcanism, extending over 100 Myrs. The Christmas Island Seamount Province (CHRISP, as it has been dubbed) lies south of the Java-Sunda Trench, and contains numerous submerged volcanic seamounts, and two sub-aerially exposed island groups—Cocos (Keeling) Islands, and Christmas Island. While recent geochronological investigations have shed light on the diverse eruption ages of the volcanics of this region, some islands/seamounts have demonstrated protracted volcanic histories, and it is not clear how the volcanic loading, tectonic subsidence, and subsequent emergence history of the islands relates to these discrete volcanic episodes. This study utilises a number of geophysical techniques to determine the crustal structure, loading and subsidence history, and last sub-aerial exposure age for the CHRISP. The study shows that flexural and subsidence modelling are reliable techniques in constraining the age of the seamounts when geochronological techniques are not possible. Utilising regional gravity signatures, we model the crustal structure underneath the Cocos (Keeling) Island, and constrain the thickness of the limestone cover between 900 and 2,100 m. Using age-depth subsidence curves for oceanic lithosphere the time since these seamounts were exposed above sea-level was determined, and a trend in exposure ages that youngs towards the west is observed. Two episodes of volcanism have been recorded at Christmas Island and they are of different origin. The younger phase in the Pliocene is a manifestation of flexure induced cracks produced in the lithosphere as it rides the subduction fore-bulge, whereas a low velocity seismic zone rising from the lower mantle, and tectonic reorganization, may be associated with the older Eocene volcanic phase, as well as much of

  9. Age, field, and petrological relationships of the Hyde School Gneiss, Adirondack lowlands, New York: Criteria for an intrusive igneous origin

    SciTech Connect

    McLelland, J. ); Perham, A. ); Chiarenzelli, J.

    1992-01-01

    Alaskitic and tonalitic rocks constituting Hyde School Gneiss (HSG) occur in 14 domical bodies in the Adirondack lowlands. Recent models have interpreted these bodies as metamorphosed rhyolitic and dacitic ash-flow deposits forming the basal member of a regional stratigraphic package. In contrast, this paper presents criteria and evidence for an intrusive origin for HSG. Field evidence includes intrusion breccias and complex crosscutting relationships involving mafic layers resembling synplutonic dikes. Petrologic constraints supporting an intrusive origin include: (1) the common occurrence of quartz-mesoperthite hypersolvus assemblages; (2) magmatic features in tonalitic, trondhjemitic, and alaskitic facies, (3) local occurrences of orthopyroxene in all facies of HSG; and (4) the development of marginal garnet-sillimanite gneiss with corundum-spinel-garnet-sillimanite assemblages yielding paleotemperatures of 780-810C and interpreted as restite remaining after anatexis of country rock metapelite by intrusions of hypersolvus granitoids. U-Pb zircon ages reported here suggest that the majority of the HSG was intruded at ca. 1230 Ma, contemporaneous with high-grade metamorphic activity in the Adirondacks and elsewhere in the SW sector of the Grenville Province. Geochronological evidence from a leucogranitic rock crosscutting metasediments on Wellesley Island suggest that these metasediments are older than 1416 {plus minus} 5 Ma.

  10. Report on TRP Analyses of Issues Concerning Within-Age versus Cross-Age Scales for the National Assessment of Educational Progress.

    ERIC Educational Resources Information Center

    Haertel, Edward H.

    The National Assessment Governing Board of Educational Progress has recently adopted the position that the National Assessment of Educational Progress (NAEP) should employ within-age scaling whenever feasible. The NAEP Technical Review panel (TRP) has studied the issue at some length, and reports on it in this analysis. The first section reviews…

  11. The origins of the National Eye Institute 1933-1968. The Fifth Charles B. Snyder Lecture.

    PubMed

    Newell, F W

    1995-01-01

    Many organizations and individuals prompted the authorization of the National Eye Institute by the United States Congress. The United States Marine Hospital and Public Health Service established a Laboratory of Hygiene in 1887, which became the research center of the National Institute of Health in 1930. The Albert D. and Mary Lasker Medical Foundation was mainly responsible for the 1945 conversion of the American Society for the Control of Cancer to the American Cancer Society, dedicated to medical research. Mildred Weisenfeld, a patient with retinitis pigmentosa, founded The Fight for Sight! in 1946 to provide funds for eye research. The Laskers invited Miss Weisenfeld to testify in support of a National Institute of Neurology, and her appeal was so persuasive that it emerged as the National Institute of Neurological Diseases and Blindness. Congressman John Fogarty and Senator Lister Hill directed the attention of the Congress and the public to the need for the Federal support of medical research. In 1960 Jules Stein, the legendary founder of the Music Corporation of America (MCA), established a new philanthropy, Research to Prevent Blindness, which provided skilled leadership in detailing the need for research in blinding disease and obtaining Congressional and Presidential approval of a new institute. The Committee for Research in Ophthalmology and Blindness was instrumental in bringing the groups interested in the welfare of the blind into harmony with groups concerned with medical research in blinding disease. The Association of University Professors of Ophthalmology was the first medical society to support the need for a National Eye Institute. The National Eye Institute was formally approved 8 August 1968 and celebrated its 25th anniversary in 1993. PMID:7555571

  12. Five Ages of Data Discovery and Access from the US National Oceanographic Data Center

    NASA Astrophysics Data System (ADS)

    Casey, K. S.; Collins, D.; Relph, J.; Li, Y.

    2012-12-01

    Since its establishment in 1961 as a mechanical bathythermograph trace processing and archive center, the US National Oceanographic Data Center (NODC) has focused its efforts on making data, collected for one purpose, discoverable and accessible to other applications. Over the years, NODC's scope expanded to include the full complexity of oceanographic data. As the scope of its data collections expanded, NODC's processes and technologies to preserve those data and make then discoverable and easily accessible evolved through five distinct ages. In the First Age, technology was limiting, the data were homogeneous in nature, and the work to make them accessible was highly manual. The Second and Third Ages saw a proliferation of inventory databases to manage and enable discovery to the rapidly expanding kinds of data being archived and the beginning of the shift of technology from a limiting factor to an enabling factor. In the Fourth Age, a tightly coupled archive, discovery, and access system emerged to unite and unify the disparate inventory systems. As technology and standards continued to mature, a Fifth Age emerged in which the tightly coupled components of the NODC Archive Management System were reengineered to form a more loosely coupled system of components, capable of leveraging and integrating community-developed discovery and access solutions. In this current age, the vast historical and modern holdings in NODC's data archive can be easily explored and accessed. This presentation will detail the history of these Five Ages of NODC, connect their evolution with developments in the broader community, and explore the possibility that a Sixth Age of data discovery and access is emerging, driven by a rapid acceleration in the adoption of standards-based data and metadata.

  13. Strong Components of Epigenetic Memory in Cultured Human Fibroblasts Related to Site of Origin and Donor Age

    PubMed Central

    Ivanov, Nikolay A.; Tao, Ran; Chenoweth, Joshua G.; Brandtjen, Anna; Mighdoll, Michelle I.; Genova, John D.; McKay, Ronald D.; Jia, Yankai; Weinberger, Daniel R.; Kleinman, Joel E.; Hyde, Thomas M.; Jaffe, Andrew E.

    2016-01-01

    Differentiating pluripotent cells from fibroblast progenitors is a potentially transformative tool in personalized medicine. We previously identified relatively greater success culturing dura-derived fibroblasts than scalp-derived fibroblasts from postmortem tissue. We hypothesized that these differences in culture success were related to epigenetic differences between the cultured fibroblasts by sampling location, and therefore generated genome-wide DNA methylation and transcriptome data on 11 intrinsically matched pairs of dural and scalp fibroblasts from donors across the lifespan (infant to 85 years). While these cultured fibroblasts were several generations removed from the primary tissue and morphologically indistinguishable, we found widespread epigenetic differences by sampling location at the single CpG (N = 101,989), region (N = 697), “block” (N = 243), and global spatial scales suggesting a strong epigenetic memory of original fibroblast location. Furthermore, many of these epigenetic differences manifested in the transcriptome, particularly at the region-level. We further identified 7,265 CpGs and 11 regions showing significant epigenetic memory related to the age of the donor, as well as an overall increased epigenetic variability, preferentially in scalp-derived fibroblasts—83% of loci were more variable in scalp, hypothesized to result from cumulative exposure to environmental stimuli in the primary tissue. By integrating publicly available DNA methylation datasets on individual cell populations in blood and brain, we identified significantly increased inter-individual variability in our scalp- and other skin-derived fibroblasts on a similar scale as epigenetic differences between different lineages of blood cells. Lastly, these epigenetic differences did not appear to be driven by somatic mutation—while we identified 64 probable de-novo variants across the 11 subjects, there was no association between mutation burden and age of the donor (p

  14. National Vocational Qualifications in the United Kingdom: Their Origins and Legacy

    ERIC Educational Resources Information Center

    Young, Michael

    2011-01-01

    National Vocational Qualifications (NVQs) were launched in the United Kingdom (excluding Scotland) in 1987 as a framework for rationalising what was described at the time as the "jungle" of existing vocational qualifications. They were never intended to be the basis for a comprehensive NQF for all qualifications; however, successive governments…

  15. Sexuality and Physical Contact in National Social Life, Health, and Aging Project Wave 2

    PubMed Central

    McClintock, Martha K.; Waite, Linda J.

    2014-01-01

    Introduction. Wave 2 of the National Social Life, Health, and Aging Project (NSHAP) includes new measures of sexual interest and behavior, as well as new measures of the context of sexual experience and the frequency and appeal of physical contact. This is the first time many of these constructs have been measured in a nationally representative sample. Method. We describe the new measures and compare the distributions of each across gender and age groups, in some cases by partnership status. Results. Two components of sexuality decrease with age among both men and women: frequency of finding an unknown person sexually attractive and receptivity to a partner’s sexual overtures. In contrast, the inclination to make one’s self sexually attractive to others was a more complicated function of partner status, gender, and age: partnered women and unpartnered men made the most effort, with the more effortful gender’s effort decreasing with age. Both men and women find nonsexual physical contact appealing but sexual physical contact is more appealing to men than women. Finally, two fifths of men and women report dissatisfaction with their partner’s frequency of caring behaviors that make later sexual interactions pleasurable, and a fifth of women and a quarter of men who had vaginal sex in the past year report dissatisfaction with amount of foreplay. Discussion. These data offer the opportunity to characterize sexual motivation in older adulthood more precisely and richly and to examine how the context of sexual experience and the nonsexual aspects of physical intimacy correlate with sexual behavior, enjoyment, and problems. PMID:25360027

  16. Personality Measures in the National Social Life, Health, and Aging Project

    PubMed Central

    Laumann, Edward O.; Waite, Linda J.; McClintock, Martha K.; Tiedt, Andrew

    2014-01-01

    Objectives. Provide recommendations for researchers on the use of the Big Five personality battery in the National Social Life, Health, and Aging Project (NSHAP), and ensure that the battery does proxy the Big Five. Also, describe the levels of Big Five traits across gender and age. Method. We used an Exploratory Structural Equation Model (ESEM) to analyze NHSAP’s personality battery, comparing NSHAP with the National Longitudinal Study of Midlife in the United States (MIDUS) and the Health and Retirement Study (HRS). Results. ESEM revealed a 5-factor structure in the NSHAP battery, but with considerable cross-loadings. When these cross-loadings were not included in the model, model fit notably worsened. Reliabilities of Big Five scales were comparable to the HRS and MIDUS, even though NSHAP’s battery is shorter. Women were considerably more Agreeable than men, although this gender gap closed among the oldest in the sample (80 years or older). Discussion. Researchers will be able to make use of NSHAP’s personality battery to examine a range of social, biological, and psychological factors at older ages, in light of individuals’ general traits. We recommend models which allow for cross-loadings. PMID:25360012

  17. National Needs of Family Planning Among US Men Aged 15 to 44 Years

    PubMed Central

    Gibbs, Susannah E.; Choiriyyah, Ifta; Sonenstein, Freya L.; Astone, Nan M.; Pleck, Joseph H.; Dariotis, Jacinda K.

    2016-01-01

    Objectives. To estimate national need for family planning services among men in the United States according to background characteristics, access to care, receipt of services, and contraception use. Methods. We used weighted data from the 2006–2010 National Survey of Family Growth to estimate the percentage of men aged 15 to 44 years (n = 10 395) in need of family planning, based on sexual behavior, fecundity, and not trying to get pregnant with his partner. Results. Overall, 60% of men were in need of family planning, defined as those who ever had vaginal sex, were fecund, and had fecund partner(s) who were not trying to get pregnant with partner or partner(s) were not currently pregnant. The greatest need was among young and unmarried men. Most men in need of family planning had access to care, but few reported receiving family planning services (< 19%), consistently using condoms (26%), or having partners consistently using contraception (41%). Conclusions. The need for engaging men aged 15 to 44 years in family planning education and care is substantial and largely unmet despite national public health priorities to include men in reducing unintended pregnancies. PMID:26890180

  18. Post-retrieval effects of icv infusions of hemicholinium in mice are dependent on the age of the original memory

    PubMed Central

    Boccia, Mariano M.; Blake, Mariano G.; Acosta, Gabriela B.; Baratti, Carlos M.

    2006-01-01

    CF-1 male mice were trained in an inhibitory avoidance task using a high footshock (1,2 mA, 50 Hz, 1 sec) in order to reduce the influence of extinction on retention performance. At 2, 7, 14, or 30 d after training, the first retention test was performed and hemicholinium (HC-3, 1.0 μg/mice), a specific inhibitor of high-affinity choline uptake in brain cholinergic neurons, was given intracerebroventricularly immediately after. Twenty four hours after treatment, mice were tested in an inhibitory avoidance task during five consecutive days, each 24 h apart. Retention performance was impaired by HC-3 when the first re-exposure took place at 2, 7, or 14 d, but the effect was no longer seen when re-exposure occurred 30 d after training. We did not find spontaneous recovery 21 d after training, when memory was retrieved 2 d after training and HC-3 was given immediately after. Although we cannot definitively discard a retrieval deficit, this lack of spontaneous recovery is in accordance with the storage-deficit interpretation. These results confirm and extend previous ones, suggesting that central cholinergic mechanisms are involved in the hypothetical reconsolidation memory processes of an inhibitory avoidance task in mice and also suggest that this participation depends on the “age” of the original memory trace. This implies that the vulnerability of a reactivated memory to a specific treatment, as the one used in this study, inversely correlates with the age of the original memory, and it is likely to determine memory reconsolidation processes. PMID:16741287

  19. Age, origin and evolution of Antarctic debris-covered glaciers: Implications for landscape evolution and long-term climate change

    NASA Astrophysics Data System (ADS)

    Mackay, Sean Leland

    Antarctic debris-covered glaciers are potential archives of long-term climate change. However, the geomorphic response of these systems to climate forcing is not well understood. To address this concern, I conducted a series of field-based and numerical modeling studies in the McMurdo Dry Valleys of Antarctica (MDV), with a focus on Mullins and Friedman glaciers. I used data and results from geophysical surveys, ice-core collection and analysis, geomorphic mapping, micro-meteorological stations, and numerical-process models to (1) determine the precise origin and distribution of englacial and supraglacial debris within these buried-ice systems, (2) quantify the fundamental processes and feedbacks that govern interactions among englacial and supraglacial debris, (3) establish a process-based model to quantify the inventory of cosmogenic nuclides within englacial and supraglacial debris, and (4) isolate the governing relationships between the evolution of englacial /supraglacial debris and regional climate forcing. Results from 93 field excavations, 21 ice cores, and 24 km of ground-penetrating radar data show that Mullins and Friedman glaciers contain vast areas of clean glacier ice interspersed with inclined layers of concentrated debris. The similarity in the pattern of englacial debris bands across both glaciers, along with model results that call for negligible basal entrainment, is best explained by episodic environmental change at valley headwalls. To constrain better the timing of debris-band formation, I developed a modeling framework that tracks the accumulation of cosmogenic 3He in englacial and supraglacial debris. Results imply that ice within Mullins Glacier increases in age non-linearly from 12 ka to ˜220 ka in areas of active flow (up to >> 1.6 Ma in areas of slow-moving-to-stagnant ice) and that englacial debris bands originate with a periodicity of ˜41 ka. Modeling studies suggest that debris bands originate in synchronicity with changes in

  20. Origin, age, and paleoclimatic setting of the Late Quaternary deposits in Wadi Feiran, Sinai Peninsula: Geomorphologic, geochronologic, and isotopic constraints

    NASA Astrophysics Data System (ADS)

    Farag, A. Z. A.; Sultan, M.; Forman, S. L.; Krishnamurthy, R. V.

    2015-12-01

    There is considerable debate on the origin, age, and paleoclimatic setting of Late Quaternary deposits within the basement complex of the Sinai Peninsula. Our research in Wadi Feiran focused on documenting the sedimentology, stratigraphy, geochemistry and chronology of Late Quaternary deposits in the Feiran (lat. 28.706 N; long. 33.665; elevation: 715 to 772 m a.m.s.l) and Tarfa (lat. 28.692 N; long. 33.933 E; elevation: 1160 to 1244 m a.m.s.l) oases. Sequence stratigraphy, analysis of remote sensed images, and groundwater levels in these two areas indicate that the investigated deposits are structurally-controlled as they are found in areas with anomalously elevated groundwater levels and upstream from shear zone/wadi intersections. Sediments are largely arenaceous upstream and transition downstream to marly successions. We infer that these sediments were not deposited in lake settings because of the absence of shorelines and associated littoral, sublittoral and deeper water facies, and the presence of rhizoliths, secondary calcite veins and gastropods, all of which suggest deposition in a spring or wetland environment. A short hydrologic residence time and/or deposition in an open water system is supported by the lack of correlation (R = 0.08) between δ18O and δ13C values in carbonate deposits. Our findings are consistent with deposition of sediments by alluvial, fluvial and paludal processes under variable hydrologic conditions and higher water table conditions. Quartz extracts from these sediments yielded optically stimulated luminescence ages between ca. 27 and 11 ka and place these wetter conditions during the last glacial period and extend the "greening" of North Africa further eastward. Our findings are consistent with models which identify the wet periods in the Late Quaternary in the Sinai Peninsula and in North Africa as being glacial periods.

  1. National Lung Screening Trial Findings by Age: Medicare-Eligible Versus Under-65 Population

    PubMed Central

    Pinsky, Paul F.; Gierada, David S.; Hocking, William; Patz, Edward F.; Kramer, Barnett S.

    2015-01-01

    Background The NLST (National Lung Screening Trial) showed reduced lung cancer mortality in high-risk participants (smoking history of ≥30 pack-years) aged 55 to 74 years who were randomly assigned to screening with low-dose computed tomography (LDCT) versus those assigned to chest radiography. An advisory panel recently expressed reservations about Medicare coverage of LDCT screening because of concerns about performance in the Medicare-aged population, which accounted for only 25% of the NLST participants. Objective To examine the results of the NLST LDCT group by age (Medicare-eligible vs. <65 years). Design Secondary analysis of a group from a randomized trial (NCT00047385). Setting 33 U.S. screening centers. Patients 19 612 participants aged 55 to 64 years (under-65 cohort) and 7110 participants aged 65 to 74 years (65+ cohort) at randomization. Intervention 3 annual rounds of LDCT screening. Measurements Demographics, smoking and medical history, screening examination adherence and results, diagnostic follow-up procedures and complications, lung cancer diagnoses, treatment, survival, and mortality. Results The aggregate false-positive rate was higher in the 65+ cohort than in the under-65 cohort (27.7% vs. 22.0%; P < 0.001). Invasive diagnostic procedures after false-positive screening results were modestly more frequent in the older cohort (3.3% vs. 2.7%; P = 0.039). Complications from invasive procedures were low in both groups (9.8% in the under-65 cohort vs. 8.5% in the 65+ cohort). Prevalence and positive predictive value (PPV) were higher in the 65+ cohort (PPV, 4.9% vs. 3.0%). Resection rates for screen-detected cancer were similar (75.6% in the under-65 cohort vs. 73.2% in the 65+ cohort). Five-year all-cause survival was lower in the 65+ cohort (55.1% vs. 64.1%; P = 0.018). Limitation The oldest screened patient was aged 76 years. Conclusion NLST participants aged 65 years or older had a higher rate of false-positive screening results than those

  2. Effect of material aging on parachute pack life: a synopsis of Sandia National Laboratories studies

    SciTech Connect

    Auerbach, I.; Mead, J.W.; Mead, K.E.; Ericksen, R.H.; Burns, F.B.; Renschler, C.L.

    1984-01-01

    A systematic study of the effects of environmental factors on nylon 66 and Kevlar 29 strength degradation in parachute components is being conducted at Sandia National Laboratories. It includes: (1) accelerated aging studies in air, inert environments, humidity, ozone, and smog; (2) a 25-year surveillance program of parachutes in a variety of natural climatic environments; (3) moisture absorption as a function of humidity; (4) effects of surface coatings normally applied to parachutes; and (5) development of nondestructive evaluation techniques which can be used to map mechanical properties over the entire parachute surface. The accelerated aging and moisture absorption studies show that air, humidity, and smog contribute to degradation. Chemiluminescence, gas chromatographic pyrograms, and uv spectroscopy show promise as nondestructive evaluation techniques.

  3. Age moderates the association of depressive symptoms and unhealthy alcohol use in the National Guard.

    PubMed

    Sahker, Ethan; Acion, Laura; Arndt, Stephan

    2016-12-01

    Unhealthy drinking is a significant problem contributing to poor health and performance of military personnel. The Iowa Army National Guard and the Iowa Department of Public Health have collaborated with the Substance Abuse and Mental Health Administration to better identify unhealthy substance use via Screening, Brief Intervention, and Referral to Treatment program (SBIRT). Yet, little research has been conducted on the Guard's use of SBIRT. This study examined depression, age, deployment status, and sex as factors contributing to unhealthy drinking. Of the Guardsmen who took part in SBIRT, 3.7% (n=75) met the criteria for unhealthy drinking and 3.9% (n=78) had some level of depression. The overall multivariate model significantly predicted unhealthy drinking (χ(2)(5)=41.41, p<0.001) with age moderating the association of depressive symptoms and unhealthy alcohol (Wald χ(2)(1)=7.16, p=0.007). These findings add to the existing understanding of factors contributing to unhealthy drinking suggesting the association between the presence of depression and unhealthy drinking depends on age of the Guradsman. This age and depression interaction may be an important diagnostic feature to consider for unhealthy drinking in the Guard. Furthermore, previous research on the general military population finds similar percentages, providing support for SBIRT as an effective screening tool in the Guard. PMID:27450908

  4. Geology, alteration, age, and origin of iron oxide-apatite deposits in Upper Eocene quartz monzonite, Zanjan district, NW Iran

    NASA Astrophysics Data System (ADS)

    Nabatian, Ghasem; Ghaderi, Majid; Corfu, Fernando; Neubauer, Franz; Bernroider, Manfred; Prokofiev, Vsevolod; Honarmand, Maryam

    2014-02-01

    Iron oxide-apatite deposits are present in Upper Eocene pyroxene-quartz monzonitic rocks of the Zanjan district, northwestern Iran. Mineralization occurred in five stages: (1) deposition of disseminated magnetite and apatite in the host rock; (2) mineralization of massive and banded magnetite ores in veins and stockwork associated with minor brecciation and calcic alteration of host rocks; (3) deposition of sulfide ores together with potassic alteration; (4) formation of quartz and carbonate veins and sericite, chlorite, epidote, silica, carbonate, and tourmaline alteration; and (5) supergene alteration and weathering. U-Pb dating of monazite inclusions in the apatite indicates an age of 39.99 ± 0.24 Ma, which is nearly coeval with the time of emplacement of the host quartz monzonite, supporting the genetic connection. Fluid inclusions in the apatite have homogenization temperatures of about 300 °C and oxygen isotopic compositions of the magnetite support precipitation from magmatic fluids. Late-stage quartz resulted from the introduction of a cooler, less saline, and isotopically depleted fluid. The iron oxide-apatite deposits in the Tarom area of the Zanjan district are typical of a magmatic-hydrothermal origin and are similar to the Kiruna-type deposits with respect to mineral assemblages, fabric and structure of the iron ores, occurrence of the ore bodies, and wall rock alteration.

  5. Origins and development of the National Laboratory System for public health testing.

    PubMed

    Astles, J Rex; White, Vanessa A; Williams, Laurina O

    2010-01-01

    Although not recognized as such, a National Laboratory System (NLS) has existed since the inception of public health laboratory (PHL) testing more than a century ago. The NLS has always relied upon the participation of clinical laboratories, both to report test results that represent public health threats and to submit specimens and isolates to PHLs for additional or confirmatory testing. Historically, a number of factors have hindered the strengthening of the relationships between clinical laboratories and PHLs, but the reality of bioterrorism and subsequent focus on strengthening public-private relationships has stimulated the development of a more robust NLS. Since 2002, there has been substantial strengthening of the NLS through the sharing of lessons learned from several demonstration projects. There is a growing emphasis on defining critical elements of the NLS, including the State Public Health Laboratory System (SPH Laboratory System) and the functions of the Laboratory Program Advisor, a position that every state should have at the center of its laboratory system's capacity-building. Additional strengthening of the NLS is occurring through (1) national biennial measurement of state PHLs' abilities to meet the Core Functions and Capabilities of State PHLs, (2) the new Laboratory System Improvement Program (L-SIP) for the SPH Laboratory System, and (3) sharing ideas to integrate and improve the SPH Laboratory System (e.g., using the L-SIP Online Resource Center). Public health emergencies, such as the recent H1N1 epidemic, illustrate and reinforce the need for a strong NLS within which federal, public health, and clinical (i.e., hospital and private reference) laboratories function in close collaboration. PMID:20518442

  6. The hierarchical factor model of ADHD: Invariant across age and national groupings?

    PubMed Central

    Toplak, Maggie E.; Sorge, Geoff B.; Flora, David B.; Chen, Wai; Banaschewski, Tobias; Buitelaar, Jan; Ebstein, Richard; Eisenberg, Jacques; Franke, Barbara; Gill, Michael; Miranda, Ana; Oades, Robert D.; Roeyers, Herbert; Rothenberger, Aribert; Sergeant, Joseph; Sonuga-Barke, Edmund; Steinhausen, Hans-Christoph; Thompson, Margaret; Tannock, Rosemary; Asherson, Philip; Faraone, Stephen V.

    2011-01-01

    Objective To examine the factor structure of Attention-Deficit/Hyperactivity Disorder (ADHD) in a clinical sample of 1373 children and adolescents with ADHD and their 1772 unselected siblings recruited from different countries across a large age range. Hierarchical and correlated factor analytic models were compared separately in the ADHD and sibling samples, across three different instruments and across parent and teacher informants. Specific consideration was given to factorial invariance analyses across different ages and different countries in the ADHD sample. Method A sample of children and adolescents between 5 and 17 years of age with ADHD and their unselected siblings was assessed. Participants were recruited from seven European countries and Israel. ADHD symptom data came from a clinical interview with parents (PACS) and questionnaires from parents and teachers (Conners Parent and Teacher). Results A hierarchical general factor model with two specific factors best represented the structure of ADHD in both the ADHD and unselected sibling groups, and across informants and instruments. The model was robust and invariant with regard to age differences in the ADHD sample. The model was not strongly invariant across different national groups in the ADHD sample, likely reflecting severity differences across the different centers and not any substantial difference in the clinical presentation of ADHD. Conclusions The results replicate previous studies of a model with a unitary ADHD component and separable specific traits of inattention and hyperactivity/impulsivity. The unique contribution of this study was finding support for this model across a large developmental and multinational/multicultural sample and its invariance across ages. PMID:22084976

  7. Early climate change consensus at the National Academy: the origins and making of "Changing Climate".

    PubMed

    Nierenberg, Nicolas; Tschinkel, Walter R; Tschinkel, Victoria J

    2010-01-01

    The 1983 National Academy of Sciences report entitled "Changing Climate," authored by a committee of physical and social scientists chaired by William Nierenberg, was an early comprehensive review of the effects of human-caused increases in the levels of atmospheric CO2. Study of the events surrounding the committee's creation, deliberations, and subsequent report demonstrates that the conclusions of the report were the consensus of the entire committee and in line with the scientific consensus of the time. This result contraverts a 2008 paper in which Naomi Oreskes, Erik M. Conway, and Matthew Shindell asserted that the report contradicted a growing consensus about climate change, and that Nierenberg for political reasons deliberately altered the summary and conclusions of the report in a way that played down the concerns of the other physical scientists on the committee. Examining the production of the report and contextualizing it in contemporaneous scientific and political discussion, we instead show how it was a multi-year effort with work divided among the various members of the committee according to their expertise. The synthesis and conclusions were expressly a joint statement of the committee and were consistent with other assessments of that time expressing deep concern over the potential issues while stopping short of recommending major policy changes due to the uncertainties, and to a lack of good alternatives. PMID:20848755

  8. The demographic and socio-economic characteristics of post-1965 immigrants to New York City: a comparative analysis by national origin.

    PubMed

    Cordero-guzman, H; Grosfoguel, R

    2000-01-01

    This article analyzes and compares the demographic and socioeconomic characteristics of persons born abroad who immigrated to New York City after 1965 and still lived in the City in 1990. Using data from the 1990 Census, the authors classify persons into the 24 largest national origin groups and compare their demographic and socioeconomic characteristics (sex, age, educational attainment, labor force participation, unemployment, occupation, income, and poverty). The authors pose and answer three empirical questions. The first question is: What are some of the main differences by national origin in the composition of persons immigrating to New York City after 1965? The second question is: What are some of the main differences in the location of post-1965 immigrants in New York's socioeconomic structure? The third question is: What are some of the differences in the economic rewards received by persons who immigrated to New York City since 1965? The authors find that immigrants with less than a high school education have higher labor force participation rates than the US-born population in the same educational category and also have slightly higher earnings. Immigrants with a high school degree have labor force participation rates close to (or slightly higher than) the average for the US-born population but their incomes are slightly lower than the average income for the US-born population. Immigrants with a college degree have participation rates similar or slightly lower than those of the US-born population while their earnings are significantly lower than those of US-born college graduates. PMID:12349807

  9. Effect of patients' age on management of acute intracranial haematoma: prospective national study

    PubMed Central

    Munro, Philip T; Smith, Rik D; Parke, Timothy R J

    2002-01-01

    Objective To determine whether the management of head injuries differs between patients aged ⩾65 years and those <65. Design Prospective observational national study over four years. Setting 25 Scottish hospitals that admit trauma patients. Participants 527 trauma patients with extradural or acute subdural haematomas. Main outcome measures Time to cranial computed tomography in the first hospital attended, rates of transfer to neurosurgical care, rates of neurosurgical intervention, length of time to operation, and mortality in inpatients in the three months after admission. Results Patients aged ⩾65 years had lower survival rates than patients <65 years. Rates were 15/18 (83%) v 165/167 (99%) for extradural haematoma (P=0.007) and 61/93 (66%) v 229/249 (92%) for acute subdural haematoma (P<0.001). Older patients were less likely to be transferred to specialist neurosurgical care (10 (56%) v 142 (85%) for extradural haematoma (P=0.005) and 56 (60%) v 192 (77%) for subdural haematoma (P=0.004)). There was no significant difference between age groups in the incidence of neurosurgical interventions in patients who were transferred. Logistic regression analysis showed that age had a significant independent effect on transfer and on survival. Older patients had higher rates of coexisting medical conditions than younger patients, but when severity of injury, initial physiological status at presentation, or previous health were controlled for in a log linear analysis, transfer rates were still lower in older patients than in younger patients (P<0.001). Conclusions Compared with those aged under 65 years, people aged 65 and over have a worse prognosis after head injury complicated by intracranial haematoma. The decision to transfer such patients to neurosurgical care seems to be biased against older patients. What is already known on this topicOlder patients with acute intracranial haematomas have significantly higher mortality and poorer functional outcome than

  10. Towards the Theory of the Age, Origin and Demise of the Universe - A Geochemical/Isotopic Perspective

    NASA Astrophysics Data System (ADS)

    Gargi, S. P.

    2005-12-01

    Both the Big Bang and Unified Field theories are derived from Einstein's well known theory of Relativity. The former only describes how the Universe was created, that is by the explosion of an extremely condensed state of energy, the Singular State. It provides no information regarding the time of its creation. The latter shows that progressively heavier matter is continually created in space-time from structured nothingness. However, Hubble later showed a strong correlation between the relative distantance of the galaxies and their receding velocity. As the array formed by this relation passes through the point of origin, it was readily accepted as the physical evidence for the Big Bang theory. Based on this relation at that time, the age of the Universe was estimated to be less than 4 Gyrs. The upper age limit of formation (TM ) of any radioactive isotope by nucleosynthesis can be determined, provided no daughter isotopes were formed at that time, from the equation: N = NA × e(-λTM); where NA is the total number of parent nuclides formed, N is the number of present-day parent nuclides, and λ is the decay constant. The above equation yields the TM age of 155, 196, 17.68, 5.56, and 7.16 Gyrs for 87Rb, 147Sm, 232Th, 235U, 238U respectively. For these elements to form at any time later than their respective TM, part of their daughter isotopes also have to be formed by nucleosynthesis. For example, if 232Th were to form about seven Gyrs ago, it would require that 85% of 208Pb/204Pb be formed by nucleosynthesis. Thus the three isotopes 232Th, 235U, and 238U, no matter when they form between 17.68 and 4.55 Gyrs ago; they all violate the Unified Field theory, either because of the formation of 208Pb before 206Pb and 207Pb, or the formation of 238U before 235U. The time of total decay (TD) for any radioactive isotope cannot be determined by using the radioactivity equation. One possible way is to estimate the TD age by extrapolating the bulk Earth parent atomic

  11. Age Differences in Reaction Time and Attention in a National Telephone Sample of Adults: Education, Sex, and Task Complexity Matter

    ERIC Educational Resources Information Center

    Tun, Patricia A.; Lachman, Margie E.

    2008-01-01

    This study demonstrated effects of age, education, and sex on complex reaction time in a large national sample (N = 3,616) with a wide range in age (32-85) and education. Participants completed speeded auditory tasks (from the MIDUS [Midlife in the U.S.] Stop and Go Switch Task) by telephone. Complexity ranged from a simple repeated task to an…

  12. Sodium intake among U.S. school-age children: National Health and Nutrition Examination Survey, 2011-2012

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Identifying current major dietary sources of sodium can enhance strategies to reduce excess sodium intake which occurs among 90% of U.S. school-aged children. We conducted a cross-sectional analysis of 24-hour dietary recall data from a nationally representative sample of 2,142 U.S. children aged 6...

  13. School Entry Age and Children's Social-Behavioral Skills: Evidence From a National Longitudinal Study of U.S. Kindergartners

    ERIC Educational Resources Information Center

    Datar, Ashlesha; Gottfried, Michael A.

    2015-01-01

    Prior research evaluating school entry age effects has largely overlooked the effects on social-behavioral skills despite the growing recognition of returns to such skills. This study is the first to examine the effects of kindergarten entry age on children's social-behavioral outcomes using 9 years of panel data on a national sample of U.S.…

  14. Grammar, Punctuation, and Spelling: Controlling the Conventions of Written English at Ages 9, 13, and 17. The Nation's Report Card.

    ERIC Educational Resources Information Center

    Applebee, Arthur N.; And Others

    The National Assessment of Educational Progress (NAEP) administered a writing task to nationally representative samples of 9-, 13-, and 17-year-old students in order to assess their abilities to use the conventions of written English. Approximately 2,000 students at each age level completed this task as part of NAEP's 1984 writing assessment.…

  15. The National Anesthesia Clinical Outcomes Registry: A Sustainable Model for the Information Age?

    PubMed Central

    Dutton, Richard P.

    2014-01-01

    Anesthesiologists care for patients of all ages, with all conceivable comorbidities, in every kind of health care facility. This leads to a significant challenge in the collection of data to describe the specialty, and in the development of evidence-based performance measures for anesthesiologists. Whereas narrowly defined medical specialties have developed registries based on manual abstraction of clinical data from the medical record (e.g., cardiac surgery), this approach would be prohibitively expensive for anesthesiology, and is unlikely to generate statistically useful data when major adverse outcomes occur a handful of times in tens of thousands of cases. The American Society of Anesthesiologists (ASA) addressed this challenge in 2008 by funding a related organization, the Anesthesia Quality Institute (AQI), to develop the National Anesthesia Clinical Outcomes Registry (NACOR). The technical development of this registry and the approach taken to define the specialty of anesthesiology and the performance of anesthesiologists may serve as a model for other specialty society efforts. PMID:25848607

  16. Aging.

    PubMed

    Park, Dong Choon; Yeo, Seung Geun

    2013-09-01

    Aging is initiated based on genetic and environmental factors that operate from the time of birth of organisms. Aging induces physiological phenomena such as reduction of cell counts, deterioration of tissue proteins, tissue atrophy, a decrease of the metabolic rate, reduction of body fluids, and calcium metabolism abnormalities, with final progression onto pathological aging. Despite the efforts from many researchers, the progression and the mechanisms of aging are not clearly understood yet. Therefore, the authors would like to introduce several theories which have gained attentions among the published theories up to date; genetic program theory, wear-and-tear theory, telomere theory, endocrine theory, DNA damage hypothesis, error catastrophe theory, the rate of living theory, mitochondrial theory, and free radical theory. Although there have been many studies that have tried to prevent aging and prolong life, here we introduce a couple of theories which have been proven more or less; food, exercise, and diet restriction. PMID:24653904

  17. Aging

    PubMed Central

    Park, Dong Choon

    2013-01-01

    Aging is initiated based on genetic and environmental factors that operate from the time of birth of organisms. Aging induces physiological phenomena such as reduction of cell counts, deterioration of tissue proteins, tissue atrophy, a decrease of the metabolic rate, reduction of body fluids, and calcium metabolism abnormalities, with final progression onto pathological aging. Despite the efforts from many researchers, the progression and the mechanisms of aging are not clearly understood yet. Therefore, the authors would like to introduce several theories which have gained attentions among the published theories up to date; genetic program theory, wear-and-tear theory, telomere theory, endocrine theory, DNA damage hypothesis, error catastrophe theory, the rate of living theory, mitochondrial theory, and free radical theory. Although there have been many studies that have tried to prevent aging and prolong life, here we introduce a couple of theories which have been proven more or less; food, exercise, and diet restriction. PMID:24653904

  18. Early child care and obesity at 12 months of age in the Danish National Birth Cohort

    PubMed Central

    Neelon, Sara E Benjamin; Andersen, Camilla Schou; Morgen, Camilla Schmidt; Kamper-Jørgensen, Mads; Oken, Emily; Gillman, Matthew W; Sørensen, Thorkild IA

    2014-01-01

    Background/Objectives Evidence suggests that the child care environment may be more obesogenic than the family home, and previous studies have found that child care use may be associated with obesity in children. Few studies, however, have focused on child care during infancy, which may be an especially vulnerable period. This study examined child care use in infancy and weight status at 12 months of age in a country where paid maternity leave is common and early child care is not as prevalent as in other developed countries. Subjects/Methods We studied 27821 children born to mothers participating in the Danish National Birth Cohort (DNBC), a longitudinal study of pregnant women enrolled between 1997 and 2002, who were also included in the Childcare Database, a national record of child care use in Denmark. The exposure was days in child care from birth to 12 months. The outcomes were sex-specific body mass index (BMI) z-score and overweight/obesity (BMI ≥85th percentile based on the World Health Organization classification) at 12 months. We conducted multivariable linear and logistic regression analyses examining child care use and weight outcomes. Results A total of 17721 (63.7%) children attended child care during their first year of life. After adjustment for potential confounders, a 30-day increment of child care was associated with a modestly higher BMI z-score at 12 months (0.03 units; 95% CI: 0.01, 0.05; p=0.003). Similarly, child care use was associated with increased odds of being overweight/obese at 12 months of age (OR 1.05; 95% CI: 1.01, 1.10; p=0.047). Conclusions Child care in the first year of life was associated with slightly higher weight at 12 months, suggesting that child care settings may be important targets for obesity prevention in infancy. PMID:25233894

  19. Trajectories of Delinquency from Age 14 to 23 in the National Longitudinal Survey of Youth Sample.

    PubMed

    Murphy, Debra A; Brecht, Mary-Lynn; Huang, David; Herbeck, Diane M

    2012-03-01

    This study utilized data from the National Longitudinal Survey of Youth to investigate risk trajectories for delinquency and factors associated with different trajectories, particularly substance use. The sample (N = 8,984) was 49% female. A group-based trajectory model was applied, which identified four distinct trajectories for both males and females: (1) a High group with delinquency rates consistently higher than other groups, with some decrease across the age range; (2) a Decreased group, beginning at high levels with substantial decrease to near zero; (3) a Moderate group experiencing some decline but remaining at moderate rates of delinquency through most of the age range; and (4) a consistently Low group, having low rates of delinquency declining to near zero by mid- to late-teens. The Low group was distinguished by several protective factors, including higher rates of maternal authoritative parenting style, possible lower acculturation (higher rates of non-English spoken at home), higher rates of religious activity, later substance use initiation, lower rates of early delinquent activity, less early experience with neighborhood or personal violence, and higher rates of perceiving penalty for wrongdoing. Conversely, the High group was characterized by several vulnerability factors-essentially the converse of the protective factors above. PMID:23105164

  20. Trajectories of Delinquency from Age 14 to 23 in the National Longitudinal Survey of Youth Sample

    PubMed Central

    Murphy, Debra A.; Brecht, Mary-Lynn; Huang, David; Herbeck, Diane M.

    2012-01-01

    This study utilized data from the National Longitudinal Survey of Youth to investigate risk trajectories for delinquency and factors associated with different trajectories, particularly substance use. The sample (N = 8,984) was 49% female. A group-based trajectory model was applied, which identified four distinct trajectories for both males and females: (1) a High group with delinquency rates consistently higher than other groups, with some decrease across the age range; (2) a Decreased group, beginning at high levels with substantial decrease to near zero; (3) a Moderate group experiencing some decline but remaining at moderate rates of delinquency through most of the age range; and (4) a consistently Low group, having low rates of delinquency declining to near zero by mid- to late-teens. The Low group was distinguished by several protective factors, including higher rates of maternal authoritative parenting style, possible lower acculturation (higher rates of non-English spoken at home), higher rates of religious activity, later substance use initiation, lower rates of early delinquent activity, less early experience with neighborhood or personal violence, and higher rates of perceiving penalty for wrongdoing. Conversely, the High group was characterized by several vulnerability factors—essentially the converse of the protective factors above. PMID:23105164

  1. Old-age pensions and population health: a global and cross-national perspective.

    PubMed

    Sjöberg, Ola

    2014-01-01

    Social security schemes can reduce poverty risk and increase resources available for individuals and families, and these schemes may therefore have an important role to play in population health in both high- and middle-income countries. This article analyses the linkage between effective coverage of old-age pension schemes and life expectancy in a sample of 93 high- and middle-income countries at the end of the twenty-first century. The analyses support the notion that social security schemes, and especially programmes with a universal approach, may have positive effects on population health, even after taking into account the effect of levels of economic development, income inequality and essential characteristics of health care systems. This article also demonstrates that there is no evident relationship between levels of economic development and social security legislation: historically, late industrialisers were often first in introducing major social security schemes, and today there is no clear cross-national relationship between levels of economic development and the proportion of the population covered by old-age pension schemes. PMID:24524644

  2. Age-specific survival of reintroduced swift fox in Badlands National Park and surrounding lands

    USGS Publications Warehouse

    Sasmal, Indrani; Klaver, Robert W.; Jenks, Jonathan A.; Schroeder, Greg M.

    2016-01-01

    In 2003, a reintroduction program was initiated at Badlands National Park (BNP), South Dakota, USA, with swift foxes (Vulpes velox) translocated from Colorado and Wyoming, USA, as part of a restoration effort to recover declining swift fox populations throughout its historical range. Estimates of age-specific survival are necessary to evaluate the potential for population growth of reintroduced populations. We used 7 years (2003–2009) of capture–recapture data of 243 pups, 29 yearlings, and 69 adult swift foxes at BNP and the surrounding area to construct Cormack–Jolly–Seber model estimates of apparent survival within a capture–mark–recapture framework using Program MARK. The best model for estimating recapture probabilities included no differences among age classes, greater recapture probabilities during early years of the monitoring effort than later years, and variation among spring, winter, and summer. Our top ranked survival model indicated pup survival differed from that of yearlings and adults and varied by month and year. The apparent annual survival probability of pups (0.47, SE = 0.10) in our study area was greater than the apparent annual survival probability of yearlings and adults (0.27, SE = 0.08). Our results indicate low survival probabilities for a reintroduced population of swift foxes in the BNP and surrounding areas. Management of reintroduced populations and future reintroductions of swift foxes should consider the effects of relative low annual survival on population demography.

  3. Health Disparities Grants Funded by National Institute on Aging: Trends Between 2000 and 2010

    PubMed Central

    Kim, Giyeon; DeCoster, Jamie; Huang, Chao-Hui; Parmelee, Patricia

    2012-01-01

    Purpose of the Study: The present study examined the characteristics of health disparities grants funded by National Institute on Aging (NIA) from 2000 to 2010. Objectives were (a) to examine longitudinal trends in health disparities–related grants funded by NIA and (b) to identify moderators of these trends. Design and Methods: Our primary data source was the National Institutes of Health Research Portfolio Online Reporting Tools Expenditures and Results (RePORTER) system. The RePORTER data were merged with data from the Carnegie Classification of Institutions of Higher Education. General linear models were used to examine the longitudinal trends and how these trends were associated with type of grant and institutional characteristics. Results: NIA funded 825 grants on health disparities between 2000 and 2010, expending approximately 330 million dollars. There was an overall linear increase over time in both the total number of grants and amount of funding, with an outlying spike during 2009. These trends were significantly influenced by several moderators including funding mechanism and type of institution. Implications: The findings highlight NIA’s current efforts to fund health disparities grants to reduce disparities among older adults. Gerontology researchers may find this information very useful for their future grant submissions. PMID:22454392

  4. [Population aging and health information from the National Household Sample Survey: contemporary demands and challenges. Introduction].

    PubMed

    Veras, Renato

    2007-10-01

    This article examines the new demographic and epidemiological reality in Brazil, based on data collected and organized in the Health Supplement of the National Household Sample Survey (PNAD-Health). It highlights the urgency of changes and innovations in health care paradigms for the elderly population with a preventive approach based on comprehensive education and care. As key concepts, the article emphasizes the need to preserve autonomy, participation, care, self-satisfaction, and the possibility of elder citizens being active in various social contexts. It also discusses the contribution by various authors to the discussion forum on Human Aging and the National Household Sample Surveys, coordinated by Cadernos de Saúde Pública/Reports in Public Health, featuring studies on access to and utilization of health services by the elderly, the epidemiological pattern of breast cancer in elderly women, and the validity of using proxy respondents in research on self-perceived health status, concluding that the PNAD data are consistent and can be used by the scientific community. PMID:17891305

  5. National and state vaccination coverage among adolescents aged 13-17 years--United States, 2012.

    PubMed

    2013-08-30

    At ages 11 through 12 years, the Advisory Committee on Immunization Practices (ACIP) recommends that preteens receive 1 dose of tetanus, diphtheria, and acellular pertussis (Tdap) vaccine, 1 dose of meningococcal conjugate (MenACWY) vaccine, and 3 doses of human papillomavirus (HPV) vaccine. ACIP recommends administration of all age-appropriate vaccines during a single visit. ACIP also recommends that pre-teens and older adolescents receive an annual influenza vaccine as well as any overdue vaccines (e.g., varicella). To monitor vaccination coverage among persons aged 13-17 years, CDC analyzed data from the National Immunization Survey-Teen (NIS-Teen). This report highlights findings of that analysis. From 2011 to 2012, coverage increased for ≥1 Tdap vaccine dose (from 78.2% to 84.6%), ≥1 MenACWY vaccine dose (from 70.5% to 74.0%) and, among males, ≥1 HPV vaccine dose (from 8.3% to 20.8%). Among females, vaccination coverage estimates for each HPV vaccine series dose were similar in 2012 compared with 2011. Coverage varied substantially among states. Regarding Healthy People 2020 targets for adolescents, 36 states achieved targets for Tdap, 12 for MenACWY, and nine for varicella vaccine coverage. Large and increasing coverage differences between Tdap and other vaccines recommended for adolescents indicate that substantial missed opportunities remain for vaccinating teens, especially against HPV infection. Health-care providers should administer recommended HPV and meningococcal vaccinations to boys and girls during the same visits when Tdap vaccine is given. In addition, whether for health problems or well-checks, providers, parents, and adolescents should use every health-care visit as an opportunity to review adolescents' immunization histories and ensure that every adolescent is fully vaccinated. PMID:23985496

  6. National Health Expenditure Growth in the 1980's: An Aging Population, New Technologies, and Increasing Competition

    PubMed Central

    Freeland, Mark S.; Schendler, Carol Ellen

    1983-01-01

    Health care spending in the United States more than tripled between 1971 and 1981, increasing from $83 billion to $287 billion. This growth in health sector spending substantially outpaced overall growth in the economy, averaging 13.2 percent per year compared to 10.5 percent for the gross national product (GNP). By 1981, one out of every ten dollars of GNP was spent on health care, compared to one out of every thirteen dollars of GNP in 1971. If current trends continue and if present health care financing arrangements remain basically unchanged, national health expenditures are projected to reach approximately $756 billion in 1990 and consume roughly 12 percent of GNP. The focal issue in health care today is cost and cost Increases. The outlook for the 1980's is for continued rapid growth but at a diminished rate. The primary force behind this moderating growth is projected lower inflation. However, real growth rates are also expected to moderate slightly. The chief factors influencing the growth of health expenditures in the eighties are expected to be aging of the population, new medical technologies, increasing competition, restrained public funding, growth in real income, increased health manpower, and a deceleration in economy-wide inflation. Managers, policy makers and providers in the health sector, as in all sectors, must include in today's decisions probable future trends. Inflation, economic shocks, and unanticipated outcomes of policies over the last decade have intensified the need for periodic assessments of individual industries and their relationship to the macro economy. This article provides such an assessment for the health care industry. Baseline current-law projections of national health expenditures are made to 1990. PMID:10309852

  7. Mineralogy and Ar-Ar Age of the Tarahumara IIE Iron, with Reference to the Origin of Alkali-Rich Materials

    NASA Technical Reports Server (NTRS)

    Takeda, Hiroshi; Bogard, Donald D.; Otsuki, Mayumi; Ishii, Teruaki

    2003-01-01

    Silicate inclusions in nine known IIE irons show diversity in mineralogy, and Colomera, Kodaikanal, Elga and Miles contain alkali-rich silicate inclusions. Bogard et al. showed evidence of a complex parent body evolution for IIE irons based on Ar-39-Ar-40 ages. Colomera contained a sanidine-rich surface inclusion and the K-enrichment trends in the Na-rich inclusions are different from those of other IIEs. To elucidate the origin of K-rich materials, we studied the mineralogy and Ar-Ar age of silicate inclusions from the Tarahumara IIE iron meteorite.

  8. Glycosylated Hemoglobin Testing in the National Social Life, Health, and Aging Project

    PubMed Central

    O’Doherty, Katie; Schumm, L. Philip; McClintock, Martha K.; Huang, Elbert S.

    2014-01-01

    Objectives. Longitudinal biomeasures of health are still new in nationally representative social science survey research. Data measuring blood sugar control provide opportunities for understanding the development of diabetes and its complications in older adults, but researchers must be aware that some of the differences across time can be due to variations in measurement procedures. This is a well-recognized issue whenever all samples cannot be assayed at the same time and we sought to present the analytic methods to quantify and adjust for the variation. Method. We collected and analyzed HbA1C, glycated hemoglobin, a biomeasure of average blood sugar concentrations within the past few months. Improvements were made in the collection protocol for Wave 2, and assays were performed by a different lab. Results. The HbA1C data obtained during Wave 1 and Wave 2 are consistent with the expected population distributions for differences by gender, age, race/ethnicity, and diabetes status. Age-adjusted mean HbA1C declined slightly from Wave 1 to Wave 2 by −0.19 (95% confidence interval [CI]: −0.27, −0.10), and the average longitudinal change was −0.12 (95% CI: −0.18, −0.06). Discussion. Collection of HbA1C in Wave 2 permits researchers to examine the relationship between HbA1C and new health and social measures added in Wave 2, and to identify factors related to the change in HbA1C. Changes in collection protocol and labs between waves may have yielded small systematic differences that require analysts to carefully interpret absolute HbA1C values. We recommend analytic methods for cross wave differences in HbA1C and steps to ensure cross wave comparability in future studies PMID:25360021

  9. Age and origin of anorthosites, charnockites, and granulites in the Central Virginia Blue Ridge: Nd and Sr isotopic evidence

    USGS Publications Warehouse

    Pettingill, H.S.; Sinha, A.K.; Tatsumoto, M.

    1984-01-01

    Rb-Sr isotopic data for anorthosites, charnockites, ferrodioritic to quartz monzonitic plutons, and high-grade gneisses of the Blue Ridge of central Virginia show evidence of post-emplacement metamorphism, but in some cases retain Grenville ages. The Pedlar River Charnockite Suite yields an isochron age of 1021 +/-36 Ma, (initial 87Sr/86Sr ratio of 0.7047 +/-6), which agrees with published U-Pb zircon ages. Five samples of that unit which contain Paleozoic mylonitic fabrics define a regression line of 683 Ma, interpreted as a mixing line with no age significance. Samples of the Roseland Anorthosite Complex show excessive scatter on a Rb-Sr evolution diagram probably due to Paleozoic (475 m.y.) metamorphism. Data from the ferrodioritic to quartz monzonitic plutons of the area yield an age of 1009 +/-26 Ma (inital ratio=0.7058 +/-4), which is in the range of the U-Pb zircon ages of 1000-1100 Ma. The Stage Road Layered Gneiss yields an age of 1147 +/-34 Ma (initial ratio of 0.7047 +/- 5). Sm-Nd data for the Pedlar River Charnockite Suite reflect a pre-Grenville age of 1489 +/-118 Ma (e{open}Nd=+6.7 +/-1.2). Data for the Roseland Anorthosite Complex and the ferrodioritic to quartz monzonitic plutons yield Grenville isochron ages of 1045 +/44 Ma (e{open}Nd=+1.0 +/-0.3) and 1027 +/-101 Ma (e{open}Nd=+1.4 +/-1.0), respectively. Two Roseland Anorthosite samples plot far above the isochron, demonstrating the effects of post-emplacement disturbance of Sm-Nd systematics, while mylonitized Pedlar River Charnockite Suite samples show no evidence of Sm-Nd redistribution. The disparity of the Sm-Nd age and other isotopic ages for the Pedlar River Charnockite Suite probably reflects a Sm-Nd "source" age, suggesting the presence of an older crust within this portion of the ca. 1 Ga old basement. ?? 1984 Springer-Verlag.

  10. Diversity of dental patterns: application on different ages using the Brazilian National Oral Health Survey.

    PubMed

    Biazevic, Maria Gabriela Haye; de Almeida, Natalie Haddad; Crosato, Edgard; Michel-Crosato, Edgard

    2011-04-15

    Methods of individual identification using human remains are widely used in forensic anthropology; however, there are few studies that use statistical methods in order to obtain a correct definition of parameters. The objectives of the study were to verify the diversity of dental patterns in the Brazilian population and analyse its application on different ages. Data from the Brazilian National Oral Health Survey were used to verify the presence and absence of dental treatment among 35,613 individuals of several age groups: 15-19, 35-44 and 65-74. Information referring to every dental element was described: higid (H), decayed (D), filled (F), missing (M) and prosthesis (P). Coincidences that were observed in pairs of homologous teeth were analysed according to clinical situation, gender and age. Ordinary findings (presented in more than 10% of pairs) and extraordinary ones (presented in less than 10% of pairs) were described. Total and conditional diversity estimates were performed. Among adolescents, H were the most frequent teeth, and the first molar teeth were the ones presenting less frequency of H. Among adults, the frequency of M teeth among females ranged from 15.17% to 71.59%, and among males they ranged from 9.00% to 87.20%. Among the elderly, M teeth were observed in the largest frequency, and anterior teeth presented fewer losses than posterior ones. M was the condition that most coincided with both sides in the elderly. In adults, some pairs of teeth presented H, but mostly pairs of teeth presented as M. Among adolescents, there was more concordance of the H component. Among male and female adolescents, we observed extraordinary findings in DMFP dental conditions in most of the teeth. Among adults, the less frequent dental condition was P, which was found in several teeth. The extraordinary findings among elderly male teeth were codes H, D, F and P; among females, they were H, D, F and P codes. The high prevalence of healthy teeth in adolescents and a

  11. Early Life Origins of Lung Ageing: Early Life Exposures and Lung Function Decline in Adulthood in Two European Cohorts Aged 28-73 Years

    PubMed Central

    Dratva, Julia; Zemp, Elisabeth; Dharmage, Shyamali C.; Accordini, Simone; Burdet, Luc; Gislason, Thorarinn; Heinrich, Joachim; Janson, Christer; Jarvis, Deborah; de Marco, Roberto; Norbäck, Dan; Pons, Marco; Real, Francisco Gómez; Sunyer, Jordi; Villani, Simona; Probst-Hensch, Nicole; Svanes, Cecilie

    2016-01-01

    Objectives Early life environment is essential for lung growth and maximally attained lung function. Whether early life exposures impact on lung function decline in adulthood, an indicator of lung ageing, has scarcely been studied. Methods Spirometry data from two time points (follow-up time 9–11 years) and information on early life exposures, health and life-style were available from 12862 persons aged 28–73 years participating in the European population-based cohorts SAPALDIA (n = 5705) and ECRHS (n = 7157). The associations of early life exposures with lung function (FEV1) decline were analysed using mixed-effects linear regression. Results Early life exposures were significantly associated with FEV1 decline, with estimates almost as large as personal smoking. FEV1 declined more rapidly among subjects born during the winter season (adjusted difference in FEV1/year of follow-up [95%CI] -2.04ml [-3.29;-0.80]), of older mothers, (-1.82 ml [-3.14;-0.49]) of smoking mothers (-1.82ml [-3.30;-0.34] or with younger siblings (-2.61ml [-3.85;-1.38]). Less rapid FEV1-decline was found in subjects who had attended daycare (3.98ml [2.78;5.18]), and indicated in subjects with pets in childhood (0.97ml [-0.16;2.09]). High maternal age and maternal smoking appeared to potentiate effects of personal smoking. The effects were independent of asthma at any age. Conclusion Early life factors predicted lung function decline decades later, suggesting that some mechanisms related lung ageing may be established early in life. Early life programming of susceptibility to adult insults could be a possible pathway that should be explored further. PMID:26811913

  12. [Anemia in women of reproductive age. The results of a national probability survey].

    PubMed

    Martínez, H; González-Cossío, T; Flores, M; Rivera-Dommarco, J; Lezana, M A; Sepúlveda-Amor, J

    1995-01-01

    Iron deficiency is one of the most prevalent forms of malnutrition which is clinically known as anemia. Functional consequences of anemia include impairment of cardiovascular performance, limitation in productivity, higher incidence of low birth weight and premature delivery, and increased maternal mortality. This paper presents a descriptive analysis of anemia in women of reproductive age in Mexico. Data were collected by the Ministry of Health through a National Nutrition Survey in 1988, which draw a representative sample from four regions: North, Center, South and Federal District. Anemia was more prevalent in pregnant (18.17%) than in non-pregnant women (15.38%). Those women living in predominantly indigenous communities had higher prevalence of anemia (24.02%) than non-indigenous women (14.67%). Anemia was more prevalent in urban areas (15.54%) than in rural (13.56%). Mean +/- standard deviation values for hemoglobin were lower in pregnant women (12.5 +/- 1.6 g/dL) than in non-pregnant ones (13.7 +/- 1.6 g/dL). Consistently, the Northern and Southern regions were worse off than the Center and the Federal District. These data indicate that anemia is a public health problem in Mexico. The functional consequences of this deficiency justify interventions to treat and prevent it. PMID:7618111

  13. Effects of Insect Origin, Gender, and Age on Transmission of Xylella fastidiosa to Grapevines by Homalodisca vitripennis (Hemiptera: Cicadellidae)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Homalodisca vitripennis (Germar) is an invasive insect vector in California, where it transmits the bacterium Xylella fastidiosa to grapevines and other crops. Transmission efficiency of X. fastidiosa to grapevines by male and female H. vitripennis originating from two geographically separated popul...

  14. Age Differences in the Big Five Across the Life Span: Evidence from Two National Samples

    PubMed Central

    Donnellan, M. Brent; Lucas, Richard E.

    2008-01-01

    Cross-sectional age differences in the Big Five personality traits were investigated using two large datasets from Britian and Germany, the British Household Panel Study (BHPS; N ≥ 14,039) and the German Socio-Economic Panel Study (GSEOP; N ≥ 20,852). Participants ranged in age from 16 to the mid 80s and completed a 15-item version of the Big Five Inventory (e.g., John & Srivastava, 1999) in either 2005 or 2006. The observed age trends were generally consistent across both datasets. Extraversion and Openness were negatively associated with age whereas Agreeableness was positively associated with age. Average levels of Conscientiousness were highest for participants in middle age. The one exception was that Neuroticism was slightly negatively associated with age in the BHPS and slightly positively associated with age in the GSEOP. Neither gender nor education level were consistent moderators of age differences in the Big Five. PMID:18808245

  15. 14C age of the "Museum Breccia" (Campi Flegrei) and its relevance for the origin of the Campanian Ignimbrite

    USGS Publications Warehouse

    Lirer, L.; Rolandi, G.; Rubin, M.

    1991-01-01

    Field stratigraphic investigations and AMS 14C dating of carbon particles in paleosols has resulted in a framework of the sequence and age of the pyroclastic products in the Campi Flegrei area of Southern Italy. The Museum Breccia cannot be the early phase of the Campanian Ignimbrite, as was previously believed, but is from a smaller and later eruption with an age of approximately 17,900 y B.P. This date also precludes its correlation with the Neapolitan Yellow Tuff (12,000 y B.P.). ?? 1991.

  16. Volunteering and Giving among American Teenagers 14 to 17 Years of Age. Findings from a National Survey. 1990 Edition.

    ERIC Educational Resources Information Center

    Hodgkinson, Virginia A.; Weitzman, Murray S.

    This survey was conducted by the Gallup organization on the volunteering and giving behavior of U.S. teenagers as a supplement to a national survey on giving and volunteering among U.S. adults. Information was obtained from in-home personal interviews with 301 teenagers from 14 to 17 years of age. Results indicated that 58 percent of teenagers…

  17. Anxiety, Depression, and Peer Relationships during Adolescence: Results from the Portuguese National Health Behaviour in School-Aged Children Survey

    ERIC Educational Resources Information Center

    de Matos, Margarida Gaspar; Barrett, Paula; Dadds, Mark; Shortt, Alison

    2003-01-01

    Used data from the Portuguese HBSC (Health Behaviour in School-Aged Children) survey, which was conducted by one of the authors who is the national representative of the European Study HBSC, a World Health Organisation collaborative study (Currie, Hurrelmann, Setterbulte, Smith, & Todd, 2000; Matos, Simoes, Carvalhosa, Reis & Canha 2000), to…

  18. National screening program for transitional ages in Korea: a new screening for strengthening primary prevention and follow-up care.

    PubMed

    Kim, Hyun Su; Shin, Dong Wook; Lee, Won Chul; Kim, Young Taek; Cho, Belong

    2012-05-01

    Screening can effectively reduce mortality and morbidity in some diseases. In Korea, a practical national screening program for chronic disease was launched in 1995 and several problems were discussed. The program focused primarily on disease detection without follow-up care. In addition, the test items were uniform regardless of subject's age, sex, or risk factors; and people with low socioeconomic status were excluded. To improve the quality of program, a new national screening program called the "National Screening Program for Transitional Ages (NSPTA)" was initiated in 2007. It targeted two age groups, ages 40 and 66, because these ages are important transition periods in one's lifecycle. Follow-up care and education for lifestyle modification has been intensified; screening tests for mental health problems and osteoporosis have been introduced. The pool of eligible participants has been expanded to include people supported by Medicaid. This review aimed to describe the contents, process, and characteristics of the NSPTA and to compare it with the previous program. In addition, some preliminary results from 2007 to 2009 were presented. Lastly, we suggest several points that need to be considered to improve the program such as enhancement of participation rates, necessity of specialized committee and research for current screening program to be supported by evidence. PMID:22661875

  19. Hearing levels in US adults aged 20-69 Years: National Health and Nutrition Examination Survey 1999-2002

    NASA Astrophysics Data System (ADS)

    Murphy, William J.; Themann, Christa L.; Franks, John R.

    2005-04-01

    The National Health and Nutrition Examination Survey (NHANES) is a nationally representative, population-based survey designed to assess the health and nutritional status of the civilian, non-institutionalized US population. Data were collected through a personal interview regarding health history and through physical examination. Earlier NHANES surveys were conducted on a periodic basis; however, in 1999, NHANES began collecting data on a continuing, annual basis. During NHANES I, which ran from 1971-1975, audiometric testing was conducted on adults aged 25-74 years. No subsequent testing of adults was conducted in the NHANES program until 1999, when NHANES began audiometric testing of adults aged 20-69 years. This report examines the hearing levels for adults in the United States and compares them with the hearing data from NHANES I. Hearing levels are grouped by age and are grouped by ethnicity and gender.

  20. 75 FR 5601 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-03

    ... Aging Special Emphasis Panel, Alzheimer's Disease Genetics. Date: March 4, 2010. Time: 7:30 p.m. to 8:30... Institute on Aging Special Emphasis Panel, Drug Development for Alzheimer's Disease. Date: March 10,...

  1. The Civil War: A Survey. Featuring Original Documents from the National Archives and Records Administration. Volume 6. Teaching with Primary Sources Series.

    ERIC Educational Resources Information Center

    West, Jean M., Ed.

    This unit of study (for grades 5-8 and up) about the U.S. Civil War features original documents from the National Archives and Records Administration. All the records used in the unit reflect the actions of the federal government or citizens' responses to these actions. These records were selected for their historical value, their legibility and…

  2. A Response to Steubing et al., "Effects of Systematic Phonics Instruction are Practically Significant": The Origin of the National Reading Panel

    ERIC Educational Resources Information Center

    Camilli, Gregory; Kim, Sun Hee; Vargas, Sadako

    2008-01-01

    A recent article by Stuebing, Barth, Cirino, Francis and Fletcher critiqued the findings of Camilli, Vargas, and Yurecko (2003) and Camilli, Wolfe, and Smith (2006). With a methodological argument, they attempted to resolve the conflict between these studies and the original report Teaching Children to Read (National Reading Panel, 2000). In…

  3. Screening Decisions for a Middle School Assistant Principalship: Effects of Principal's Sex, National Origin of Applicants, and Job Experience of Applicants

    ERIC Educational Resources Information Center

    Young, I. Phillip; Sever, Wesley Richard

    2011-01-01

    Screening decisions of female and male middle school principals were examined for applicants varying in national origin (Hispanic versus non-Hispanic) and type of job experience (direct versus indirect) for a middle school principalship. Principals' reactions were assessed according to perceived qualifications of applicants, probability of…

  4. On the origin and tectonic significance of the intra-plate events of Grenvillian-type age in South America: A discussion

    NASA Astrophysics Data System (ADS)

    Cordani, Umberto G.; Fraga, Leda Maria; Reis, Nelson; Tassinari, Colombo C. G.; Brito-Neves, Benjamim B.

    2010-01-01

    The objective of this article is to examine the available evidence of intra-plate tectonic episodes of "Grenvillian-type age", affecting the South-American continent, assessing their possible causal correlation with the tectonic processes occurring within the orogenic belts active at their margins. For the Amazonian Craton, the active margin is represented by the Rondonian-San Ignacio and Sunsas belts. However, active margins of similar age are not recognized for the São Francisco and the Rio de La Plata Cratons, and the intra-plate events over them could be reflections of the Kibaran, Irumide or Namaqua orogenic collisions in Africa. Grenvillian-type age events over the Amazonian Craton can be described in four different aspects: shearing and tectonic reactivation along zones of weakness, cratogenic granitic magmatism, alkaline ring complexes, and pervasive regional heating in some localized regions. The first of them may reflect the compressional stresses at active margins, however the others may have different origins. Within the type-region of the K'Mudku tectono thermal episode, mylonites and pseudotachylites cut across the regional granitoid and metamorphic rocks. These shear belts developed under low-to-moderate temperature conditions, that induced resetting of K-Ar and Rb-Sr mineral ages. In the São Francisco Craton, extensional and compressional events of Grenvillian-type age are well registered by the structural features exhibited by the sedimentary rocks of the Espinhaço Supergroup. For example, in Bahia state, an Appalachian-style structure is observed, with large synclines and anticlines extending along hundreds of kilometers. The major difference between the Amazonian and the Congo-São Francisco Cratons is related to heat originated from the Earth's interior. Amazonia exhibits very large areas heated up to 350-400 °C, where the K'Mudku thermo-tectonic episodes were detected. In addition, Amazonia comprises a large amount of cratogenic granitic

  5. Leader Age and National Condition: A Longitudinal Analysis of 25 European Monarchs.

    ERIC Educational Resources Information Center

    Simonton, Dean Keith

    1984-01-01

    Analyzed the reigns of 25 long-tenured European absolute monarchs for 238 five-year age periods to determine the relationship between age and achievement in the politico-military domain. Results indicated that age negatively correlated with success in foreign wars and with treaty negotiation, and positively correlated with civil instability at…

  6. Graduates' Perspectives on a National Specialized Program in Social Work and Aging

    ERIC Educational Resources Information Center

    Greenfield, Emily A.; Shpiegel, Svetlana

    2012-01-01

    Recognizing the growing need for social workers with specialized training in aging, the Hartford Partnership Program for Aging Education (HPPAE) has developed as a nationwide initiative to enhance aging education for master's-level social work students. This study presents a content analysis of answers to 2 open-ended questions in a national…

  7. The rotational origin and state of the whole: its relation to growth, fertility, aging, death, and diseases.

    PubMed

    Pierpaoli, Walter

    2005-12-01

    The purpose of my report is to synthetically summarize the concept of the rotatory essence of the Whole and to bring evidence that while aging responds to a precise inner "program" of the mammalian and any other species' "brain," acceleration of aging and all diseases are simply the direct outcome of a desynchronization of our inner "clock" with respect to the precise periodicity and hormone-integrated rhythmicity of the solar system. Those neuroendocrine, hormonal derangements of our inner clock are easily detectable and inevitably anticipate even by decades the onset of all diseases (autoimmune, cardiovascular, neurodegenerative, neoplastic). I will introduce those interventions capable of detecting early alterations and of restoring hormonal rhythmicity, which will consequently restore immunological surveillance in a positive cascade sequence. PMID:16399884

  8. Use of radium isotopes to determine the age and origin of radioactive barite at oil-field production sites

    USGS Publications Warehouse

    Zielinski, R.A.; Otton, J.K.; Budahn, J.R.

    2001-01-01

    Radium-bearing barite (radiobarite) is a common constituent of scale and sludge deposits that form in oil-field production equipment. The barite forms as a precipitate from radium-bearing, saline formation water that is pumped to the surface along with oil. Radioactivity levels in some oil-field equipment and in soils contaminated by scale and sludge can be sufficiently high to pose a potential health threat. Accurate determinations of radium isotopes (226Ra+228Ra) in soils are required to establish the level of soil contamination and the volume of soil that may exceed regulatory limits for total radium content. In this study the radium isotopic data are used to provide estimates of the age of formation of the radiobarite contaminant. Age estimates require that highly insoluble radiobarite approximates a chemically closed system from the time of its formation. Age estimates are based on the decay of short-lived 228Ra (half-life=5.76 years) compared to 226Ra (half-life=1600 years). Present activity ratios of 228Ra/226Ra in radiobarite-rich scale or highly contaminated soil are compared to initial ratios at the time of radiobarite precipitation. Initial ratios are estimated by measurements of saline water or recent barite precipitates at the site or by considering a range of probable initial ratios based on reported values in modern oil-field brines. At sites that contain two distinct radiobarite sources of different age, the soils containing mixtures of sources can be identified, and mixing proportions quantified using radium concentration and isotopic data. These uses of radium isotope data provide more description of contamination history and can possibly address liability issues. Copyright ?? 2000 .

  9. The Relationship between Functional Capacity and Community Responsibilities in Middle-aged and Older Latinos of Mexican Origin with Chronic Psychosis

    PubMed Central

    Cardenas, Veronica; Mausbach, Brent T.; Barrio, Concepcion; Bucardo, Jesus; Jeste, Dilip; Patterson, Thomas

    2008-01-01

    The purpose of this study was to examine the relationship between scores on the UCSD Performance-based Skills Assessment (UPSA), a performance-based measure of functional capacity, and level of patient community responsibilities (i.e., work for pay; volunteer work; attend school; household duties) in a Latino sample. Participants were 58 middle-aged and older Latinos of Mexican origin (mean age = 48.8 years) with a diagnosis of schizophrenia or schizoaffective disorder. We conducted an analysis of covariance (ANCOVA), controlling for age, symptoms of psychosis, and participant language, to determine if greater participation in community responsibilities was associated with higher functional capacity, as measured by the UPSA. Results indicated significant group differences in UPSA scores (F = 5.11, df = 2,51; p = .009), with patients reporting only a single community responsibility having significantly higher UPSA scores than those reporting zero community responsibilities (p = .016) and those reporting two responsibilities scoring significantly higher than those reporting zero community responsibility (p = .008). There were no differences found between those reporting one and those reporting two community responsibilities (p= .256). In contrast, no group differences were observed on the Dementia Rating Scale, a global measure of cognitive functioning (F = 2.14, df = 2,51; p = .128). These results provide initial support for the validity of the UPSA in Latino patients of Mexican origin, and suggest that improvement in functional capacity (i.e., UPSA scores) may be associated with increased capacity for greater community involvement in this population. PMID:17936585

  10. Occurrence and origin of minerals in a chamosite-bearing coal of Late Permian age, Zhaotong, Yunnan, China

    USGS Publications Warehouse

    Dai, S.; Chou, C.-L.

    2007-01-01

    The minerals found in the no.5 coal (Late Permian) from the Zhaotong Coalfield, Yunnan Province, southwestern China, have been examined and found to consist mainly of kaolinite, pyrite, chamosite, quartz, and calcite, with trace amounts of illite and mixed-layer illite-smectite. The proportion of chamosite in clay minerals ranges from 32 to 56 wt%, with an average of 46 wt%. Chamosite is distributed not only in collodetrinite, but also occurs as cell fillings in fusinite, semifusinite, and telinite. The high content and mode of occurrence of chamosite in this mine indicate its formation by interaction of kaolinite with Fe-Mg-rich fluids during early diagenesis. Except for a minor amount of terfigenous quartz, most quartz is of authigenic origin and formed from kaolinite desilication. The calcite content of the no. 5 coal is 1.4-6.3% (with an average of 3%) and is distributed in collodetrinite and as cell fillings of coal-forming plants. Calcite originated from seawater invasion during peat accumulation. Pyrite occurs in several ways: as massive, framboidal, isolated enhedral/ anhedral, and euhedral forms. In addition, the presence of a large amount of pyritized red algae provides strong evidence of seawater invasion during peat accumulation. The red algae may have played an important role in the enrichment of sulfur in the coal. The characteristic assemblage of minerals in this mine resulted from a unique basinal environment in which the mineral matter was derived from a basaltic source region, volcanic activity, and seawater transgression during coal formation.

  11. The unexpected outcomes of anti-aging, rejuvenation, and life extension studies: an origin of modern therapies.

    PubMed

    Stambler, Ilia

    2014-06-01

    The search for life-extending interventions has been often perceived as a purely academic pursuit, or as an unorthodox medical enterprise, with little or no practical outcome. Yet, in fact, these studies, explicitly aiming to prolong human life, often constituted a formidable, though hardly ever acknowledged, motivation for biomedical research and discovery. At least several modern biomedical fields have originated directly from rejuvenation and life extension research: (1) Hormone replacement therapy was born in Charles-Edouard Brown-Séquard's rejuvenation experiments with animal gland extracts (1889). (2) Probiotic diets originated in Elie Metchnikoff's conception of radically prolonged "orthobiosis" (c. 1900). (3) The development of clinical endocrinology owed much to Eugen Steinach's "endocrine rejuvenation" operations (c. 1910s-1920s). (4) Tissue transplantations in humans (allografts and xenografts) were first widely performed in Serge Voronoff's "rejuvenation by grafting" experiments (c. 1910s-1920s). (5) Tissue engineering was pioneered during Alexis Carrel's work on cell and tissue immortalization (c. 1900-1920). (6) Cell therapy (and particularly human embryonic cell therapy) was first widely conducted by Paul Niehans for the purposes of rejuvenation as early as the 1930s. Thus, the pursuit of life extension and rejuvenation has constituted an inseparable and crucial element in the history of biomedicine. Notably, the common principle of these studies was the proactive maintenance of stable, long-term homeostasis of the entire organism. PMID:24524368

  12. Cable Polymer Aging and Condition Monitoring Research at Sandia National Laboratores Under the Nuclear Energy Plant Optimization (NEPO) Program

    SciTech Connect

    K. Gillen; R. Assink; R. Bernstein

    2005-12-23

    This report describes cable polymer aging and condition monitoring research performed at Sandia National Laboratories under the Nuclear Energy Plant Optimization (NEPO) Program from 2000 to 2005. The research results apply to low-voltage cable insulation and Program from 2000 to 2005. The research results apply to low-voltage cable insulation and jacket materials that are commonly used in U.S. nuclear power plants. The research builds upon and is liked to research performed at Sandia from 1977 through 1986, sponsored by the U.S. Nuclear Regulatory Commission. Aged and unaged specimens from that research remained available and were subjected to further testing under the NEPO research effort.The documented results from the earlier research were complemented by subjecting the specimens to new condition monitoring tests. Additional aging regimens were applied to additional specimens to develop aging models for key cable jacket and insulation materials

  13. AGE AND ORIGIN OF BASE- AND PRECIOUS-METAL VEINS OF THE COEUR D'ALENE MINING DISTRICT, IDAHO

    SciTech Connect

    Fleck, R J; Criss, R E; Eaton, G F; Cleland, R W; Wavra, C S; Bond, W D

    2000-11-07

    Ore-bearing quartz-carbonate veins of the Coeur d'Alene mining district yield {sup 87}Sr/{sup 86}Sr ratios of 0.74 to >1.60 for low-Rb/Sr, carbonate gangue minerals, similar to current ranges measured in Middle Proterozoic, high-Rb/Sr rocks of the Belt Supergroup. Stable-isotope and fluid-inclusion studies establish a genetic relationship between vein formation and metamorphic-hydrothermal systems of the region. These extraordinary {sup 87}Sr/{sup 86}Sr ratios require accumulation of radiogenic {sup 87}Sr in a high Rb/Sr system over an extended period prior to incorporation of Sr into the veins by hydrothermal processes. Evaluation of the age and composition of potential sources of highly radiogenic Sr indicates that the ore-bearing veins of the Coeur d'Alene district formed within the last 200 Ma from components scavenged from sedimentary and metasedimentary rocks of the Belt Supergroup, the primary host-rocks of the district. These results are consistent with a Cretaceous or Early Tertiary age for these veins. Pb-Zn deposits that yield Pb isotope, K-Ar, and Ar-Ar results indicative of a Proterozoic age probably formed during deposition or diagenesis of the Belt Supergroup at 1350-1500 Ma, possibly as Sullivan-type syngenetic deposits. K-Ar and Rb-Sr apparent ages and {delta}{sup 18}O values of Belt Supergroup rocks decrease southward from the Coeur d'Alene district toward the Idaho batholith, normal to the trends of metamorphic isograds, fold axes, foliation, and the major reverse faults of the district. Isoclinal folding, thrust faulting, high-temperature metamorphism, granitic plutonism, and regional-scale metamorphic-hydrothermal activity is documented in the region between 140 Ma and 45 Ma, but no similar combination of events is recognized for Late Proterozoic time. Combined with Sr results from the veins, the evidence strongly favors formation of the ore-bearing carbonate veins of the district by fluids related to a complex metamorphic-hydrothermal system

  14. Isolation of Left Common Carotid Artery with Its Origin Proximal to Patent Ductus Arteriosus Presenting in Adult Age

    PubMed Central

    Joshi, Anagha R.; Joshi, Saurabh; Kale, Kiran; Jain, Rahul; Bava, Jernail Singh

    2016-01-01

    Anomalies of aortic arch are a common occurrence. Such anomalies of right sided aortic arch with its various branching patterns are of clinical importance. Rarer anomalies include isolation (deficient connection) of either left subclavian artery or left common carotid artery; that is, they do not have their origin from aorta or its major branches. We present a case of an 18-year-old male who presented with gradual onset pulsatile swelling with bruit in neck on left side and was evaluated by CT brain and neck angiography. CT angiography revealed right sided aortic arch with aberrant left subclavian artery and isolated left common carotid artery. Very few cases of such an anomaly have been documented in the literature but none in an adult. PMID:27213071

  15. Occurrence and origin of minerals in a chamosite-bearing coal of Late Permian age, Zhaotong, Yunnan, China

    SciTech Connect

    Dai, S.; Chou, C.L.

    2007-08-15

    The minerals found in the no. 5 coal (Late Permian) from the Zhaotong Coalfield, Yunnan Province, southwestern China, have been examined and found to consist mainly of kaolinite, pyrite, chamosite, quartz, and calcite, with trace amounts of illite and mixed-layer illite-smectite. The proportion of chamosite in clay minerals ranges from 32 to 56 wt%, with an average of 46 wt%. Chamosite is distributed not only in collodetrinite, but also occurs as cell fillings in fusinite, semifusinite, and telinite. The high content and mode of occurrence of chamosite in this mine indicate its formation by interaction of kaolinite with Fe-Mg-rich fluids during early diagenesis. Except for a minor amount of terrigenous quartz, most quartz is of authigenic origin and formed from kaolinite desilication. The calcite content of the no. 5 coal is 1.4-6.3% (with an average of 3%) and is distributed in collodetrinite and as cell fillings of coal-forming plants. Calcite originated from seawater invasion during peat accumulation. Pyrite occurs in several ways: as massive, framboidal, isolated enhedral/anhedral, and euhedral forms. In addition, the presence of a large amount of pyritized red algae provides strong evidence of seawater invasion during peat accumulation. The red algae may have played an important role in the enrichment of sulfur in the coal. The characteristic assemblage of minerals in this mine resulted from a unique basinal environment in which the mineral matter was derived from a basaltic source region, volcanic activity, and seawater transgression during coal formation.

  16. Constraining the age of the NGC 4565 H I disk WARP: Determining the origin of gas WARPS

    SciTech Connect

    Radburn-Smith, David J.; Dalcanton, Julianne J.; Stilp, Adrienne M.; De Jong, Roelof S.; Streich, David; Bell, Eric F.; Monachesi, Antonela; Dolphin, Andrew E.; Holwerda, Benne W.; Bailin, Jeremy

    2014-01-01

    We have mapped the distribution of young and old stars in the gaseous H I warp of NGC 4565. We find a clear correlation of young stars (<600 Myr) with the warp but no coincident old stars (>1 Gyr), which places an upper limit on the age of the structure. The formation rate of the young stars, which increased ∼300 Myr ago relative to the surrounding regions, is (6.3{sub −1.5}{sup +2.5})×10{sup −5} M {sub ☉} yr{sup –1} kpc{sup –2}. This implies a ∼60 ± 20 Gyr depletion time of the H I warp, similar to the timescales calculated for the outer H I disks of nearby spiral galaxies. While some stars associated with the warp fall into the asymptotic giant branch (AGB) region of the color-magnitude diagram, where stars could be as old as 1 Gyr, further investigation suggests that they may be interlopers rather than real AGB stars. We discuss the implications of these age constraints for the formation of H I warps and the gas fueling of disk galaxies.

  17. Aspen Ecology in Rocky Mountain National Park: Age Distribution, Genetics, and the Effects of Elk Herbivory

    USGS Publications Warehouse

    Zeigenfuss, Linda C.; Binkley, Dan; Tuskan, Gerald A.; Romme, William H.; Yin, Tongming; DiFazio, Stephen; Singer, Francis J.

    2008-01-01

    Lack of recruitment and canopy replacement of aspen (Populus tremuloides) stands that grow on the edges of grasslands on the low-elevation elk (Cervus elaphus) winter range of Rocky Mountain National Park (RMNP) in Colorado have been a cause of concern for more than 70 years. We used a combination of traditional dendrochronology and genetic techniques as well as measuring the characteristics of regenerating and nonregenerating stands on the elk winter range to determine when and under what conditions and estimated elk densities these stands established and through what mechanisms they may regenerate. The period from 1975 to 1995 at low elevation on the east side had 80-95 percent fewer aspen stems than would be expected based on the trend from 1855 through 1965. The age structure of aspen in the park indicates that the interacting effects of fires, elk population changes, and livestock grazing had more-or-less consistent effects on aspen from 1855 to 1965. The lack of a significant change in aspen numbers in recent decades in the higher elevation and west side parts of the park supports the idea that the extensive effects of elk browsing have been more important in reducing aspen numbers than other factors. The genetic variation of aspen populations in RMNP is high at the molecular level. We expected to find that most patches of aspen in the park were composed of a single clone of genetically identical trees, but in fact just 7 percent of measured aspen patches consisted of a single clone. A large frequency of polyploid (triploid and tetraploid) genotypes were found on the low elevation, east-side elk winter range. Nonregenerating aspen stands on the winter range had greater annual offtake, shorter saplings, and lower density of mid-height (1.5-2.5 m) saplings than regenerating stands. Overwinter elk browsing, however, did not appear to inhibit the leader length of aspen saplings. The winter range aspen stands of RMNP appear to be highly resilient in the face of

  18. Investigation of origin for seawater intrusion using geophysical well logs and absolute ages of volcanic cores in the eastern part of Jeju Island

    NASA Astrophysics Data System (ADS)

    Hwang, Seho; Shin, Jehyun

    2010-05-01

    Jeju located in the southern extremity of Korea is volcanic island, one of best-known tourist attractions in Korea. Jeju Province operates the monitoring boreholes for the evaluation of groundwater resources in coastal area. Major rock types identified from drill cores are trachybasalt, acicular basalt, scoria, hyalocastite, tuff, unconsolidated U formation, and seoguipo formation and so on. Various conventional geophysical well loggings including radioactive logs (natural gamma log, dual neutron log, and gamma-gamma log), electrical log (or electromagnetic induction log), caliper log, fluid temperature/ conductivity log, and televiewer logs have been conducted to identify basalt sequences and permeable zone, and verify seawater intrusion in monitoring boreholes. The conductivity logs clearly show the fresh water-saline water boundaries, but we find it hard to identify the permeable zones because of the mixed groundwater within the boreholes. Temperature gradient logs are mostly related with lithologic boundaries and permeable zones intersected by boreholes of eastern coasts. The wide range of periodic electrical conductivity logging in the deeper depth of monitoring boreholes indicates the possibility of submarine groundwater discharge. However we did not clearly understand the origin of seawater intrusion in the eastern coast until now. So we analysis the electrical conductivity profiles, record of sea-level change and 40Ar/39Ar absolute ages of volcanic rock cores from twenty boreholes in east coast. From comparing absolute ages of volcanic rock cores and sea-level of their ages, we find that the almost ages of depth showing high salinity groundwater are about 100 Ka, and from 130Ka to about 180Ka. The former is after the interglacial period and the latter is illinoian. These results indicate that the abrupt raising of sea level after illinoian formed the regional coast, and the zone of present seawater intrusion also are above the depth of illinoin period. So

  19. Age, origin, and significance of an unconformity that predates island-arc volcanism in the northern Sierra Nevada

    NASA Astrophysics Data System (ADS)

    Varga, Robert J.; Moores, Eldridge M.

    1981-11-01

    The paleogeographic position of rocks of the northern Sierra Nevada relative to North America has long been the topic of debate. A detailed study of the Lakes Basin region of the northern Sierra Nevada substantiates that the Shoo Fly Complex, of early Paleozoic age, was folded and unconformably overlain by an island-arc sequence in late Paleozoic time. Microfossils recovered during the study represent the first in situ fauna ever collected from the Shoo Fly Complex and provide an Ordovician-Silurian lower limit on the early deformation. Late Jurassic (Nevadan) deformation strongly affected all rocks in the region. Regional considerations suggest that mid-Paleozoic deformation may have been widespread in the Sierra Nevada and could indicate an early phase of an eastward-prograding suture that ultimately resulted in emplacement of the Roberts Mountain allochthon of the Great Basin. *Present address: Union Oil Research Center, Box 76, Brea, California 92621

  20. Social Work Faculty's Knowledge of Aging: Results from a National Sample

    ERIC Educational Resources Information Center

    Wang, Donna S.; Chonody, Jill M.; Krase, Kathryn

    2013-01-01

    Social work students have reported in previous studies that they receive insufficient coursework and training to work effectively with older adults. A critical factor in these deficiencies may be the level of knowledge of social work faculty. This study sought to assess social work faculty's knowledge of aging using the Knowledge of Aging for…

  1. High-precision 40Ar/ 39Ar age constraints on the basal Lanqi Formation and its implications for the origin of angiosperm plants

    NASA Astrophysics Data System (ADS)

    Chang, Su-chin; Zhang, Haichun; Renne, Paul R.; Fang, Yan

    2009-03-01

    Abundant Mesozoic terrestrial fossils were discovered in the Haifanggou Formation and the overlying Lanqi Formation in northeastern China. The recent discovery of Schmeissneria sinensis from the Haifanggou Formation provides evidence that the origin of angiosperms could be much earlier than previously believed. 92 taxa of plant fossils from the Lanqi Formation provide unique opportunities to understand the floral evolution and its diversification in the Mesozoic. Here we present robust high-precision 40Ar/ 39Ar data of 160.7 ± 0.4 Ma and 158.7 ± 0.6 Ma for two tuffs from the lowest part of the Lanqi Formation near the main outcrop of floral fossils in Beipiao City, Liaoning, China. Our age results indicate the whole Lanqi Formation was deposited in the Late Jurassic; consequently, the underlying Haifanggou Formation and Schmeissneria sinensis are at least Middle Jurassic in age. Besides its importance for floral evolution, our high-precision age results for the basal Lanqi Formation indicate the paleoenvironment in the north margin of the North China Craton was dry and hot in the Late Jurassic. Moreover, the new age data for the basal Lanqi Formation suggest that the unearthed fossils from the Haifanggou Formation and Lanqi Formation should be equivalent to the Daohugou Biota in Inner Mongolia, China.

  2. Volatile compounds and sensorial characterization of wines from four Spanish denominations of origin, aged in Spanish Rebollo (Quercus pyrenaica Willd.) oak wood barrels.

    PubMed

    Fernández de Simón, Brígida; Cadahía, Estrella; Sanz, Miriam; Poveda, Pilar; Perez-Magariño, Silvia; Ortega-Heras, Miriam; González-Huerta, Carlos

    2008-10-01

    The evolution of almost 40 oak-related volatile compounds and the sensorial characteristics of red wines from four Spanish denominations of origin (DOs) (Bierzo, Toro, Ribera de Duero, and Rioja) during aging in barrels made of Rebollo oak wood, Quercus pyrenaica, were studied and compared to the same wines aged in American and French oak barrels. Each oak wood added unique and special characteristics to the wine, and in addition, each wine showed a different ability to extract the compounds, which result in these characteristics from the oak wood. In general, wines aged in Q. pyrenaica wood were characterized by high levels of eugenol, guaiacol, and other volatile phenols. In regards to compounds like cis-whiskylactone or maltol, the behavior of this wood is very similar to that of American oaks. When considering phenolic aldehydes and ketones, the levels of these compounds are intermediate between those of French and American woods and depend greatly on the type of wine. The type of oak, on the other hand, does not affect the chromatic characteristics of the wines. In sensory analysis, the biggest differences are found in the olfactory phase. Among the four DOs studied, wine aged in Q. pyrenaica presented the highest notes of wood, with more aromas of roasting, toasting, milky coffee, spices, or wine-wood interactions. The wines aged in barrels made of Q. pyrenaica wood were highly regarded, and preference was shown for them over those same wines when they had been aged in barrels of American or French oak. PMID:18778067

  3. Age-Related Changes in the Cardiometabolic Profiles in Singapore Resident Adult Population: Findings from the National Health Survey 2010.

    PubMed

    Loh, Tze Ping; Ma, Stefan; Heng, Derrick; Khoo, Chin Meng

    2016-01-01

    We describe the centile trends of the blood pressure, glycemia and lipid profiles as well as renal function of a representative population who participated in the Singapore National Health Survey in 2010. Representative survey population was sampled in two phases, first using geographical/ residential dwelling type stratification, followed up ethnicity. 2,407 survey participants without any self-reported medical or medication history for diabetes mellitus, hypertension and dyslipidemia were included in this analysis. All biochemistry analyses were performed on Roche platforms. After excluding outliers using Tukey's criteria, the results of the remaining participants were subjected to lambda-mu-sigma (LMS) analysis. In men, systolic blood pressure increased linearly with age. By contrast, an upward inflection around late 40s was seen in women. The diastolic blood pressure was highest in men in the late 30s-50s age group, and in women in the late 50s-60s age group. All glycemia-related parameters, i.e. fasting and 2-hour plasma glucose and HbA1c concentrations increased with age, although the rate of increase differed between the tests. Total cholesterol and LDL-cholesterol concentrations increased with age, which became attenuated between the early 30s and late 50s in men, and declined thereafter. In women, total cholesterol and LDL-cholesterol concentrations gradually increased with age until late 30s, when there is an upward inflection, plateauing after late 50s. Our findings indicate that diagnostic performance of laboratory tests for diabetes may be age-sensitive. Unfavourable age-related cardiovascular risk profiles suggest that the burden of cardiovascular disease in this population will increase with aging population. PMID:27570971

  4. Age-Related Changes in the Cardiometabolic Profiles in Singapore Resident Adult Population: Findings from the National Health Survey 2010

    PubMed Central

    Loh, Tze Ping; Ma, Stefan; Heng, Derrick; Khoo, Chin Meng

    2016-01-01

    We describe the centile trends of the blood pressure, glycemia and lipid profiles as well as renal function of a representative population who participated in the Singapore National Health Survey in 2010. Representative survey population was sampled in two phases, first using geographical/ residential dwelling type stratification, followed up ethnicity. 2,407 survey participants without any self-reported medical or medication history for diabetes mellitus, hypertension and dyslipidemia were included in this analysis. All biochemistry analyses were performed on Roche platforms. After excluding outliers using Tukey's criteria, the results of the remaining participants were subjected to lambda-mu-sigma (LMS) analysis. In men, systolic blood pressure increased linearly with age. By contrast, an upward inflection around late 40s was seen in women. The diastolic blood pressure was highest in men in the late 30s-50s age group, and in women in the late 50s-60s age group. All glycemia-related parameters, i.e. fasting and 2-hour plasma glucose and HbA1c concentrations increased with age, although the rate of increase differed between the tests. Total cholesterol and LDL-cholesterol concentrations increased with age, which became attenuated between the early 30s and late 50s in men, and declined thereafter. In women, total cholesterol and LDL-cholesterol concentrations gradually increased with age until late 30s, when there is an upward inflection, plateauing after late 50s. Our findings indicate that diagnostic performance of laboratory tests for diabetes may be age-sensitive. Unfavourable age-related cardiovascular risk profiles suggest that the burden of cardiovascular disease in this population will increase with aging population. PMID:27570971

  5. Age and origin of base and precious metal veins of the Coeur d'Alene mining district, Idaho

    USGS Publications Warehouse

    Fleck, R.J.; Criss, R.E.; Eaton, G.F.; Cleland, R.W.; Wavra, C.S.; Bond, W.D.

    2002-01-01

    Ore-bearing quartz-carbonate veins of the Coeur d'Alene mining district yield 87Sr/86Sr ratios of 0.74 to >1.60 for low Rb/Sr, carbonate gangue minerals, similar to current ranges measured in Middle Proterozoic, high Rb/Sr rocks of the Belt Supergroup. Stable isotope and fluid inclusion studies establish a genetic relationship between vein formation and metamorphic-hydrothermal systems of the region. These extraordinary 87Sr/86Sr ratios require accumulation of radiogenic 87Sr in a high Rb/Sr system over an extended period prior to incorporation of Sr into the hydrothermal veins. Evaluation of the age and composition of potential sources of highly radiogenic Sr indicates that the ore-bearing veins of the Coeur d'Alene district formed during the Cretaceous from components scavenged from rocks of the Belt Supergroup, the primary host rocks of the district. Proterozoic Pb isotope ratios observed in galena from many Coeur d'Alene veins were established when Pb separated from uranium during deposition or diagenesis of the Belt Supergroup at 1400 to 1500 Ma, possibly as disseminated syngenetic deposits. K-Ar and Rb-Sr apparent ages and ??18O values of Belt Supergroup rocks decrease from the Coeur d'Alene district toward the Idaho and Kaniksu batholiths, approximately normal to the trends of metamorphic isograds, fold axes, foliation, and the major reverse faults of the district. Isoclinal folding, thrust faulting, high-temperature metamorphism, granitic plutonism, and regional-scale metamorphic-hydrothermal activity is documented in the region between 140 and 45 Ma, representing the only such combination of events in the Coeur d'Alene region subsequent to about 1300 Ma. The Sr and oxygen results and geologic evidence favor formation of the ore-bearing carbonate veins by fluids related to a complex metamorphic-hydrothermal system during the Cretaceous. Pb with Proterozoic isotopic compositions was probably mobilized and incorporated like other metals into the hydrothermal

  6. Age and origin of Pan-African granites and associated U-Mo mineralization at Ekomédion, southwestern Cameroon

    NASA Astrophysics Data System (ADS)

    Mosoh Bambi, C. K.; Frimmel, H. E.; Zeh, A.; Suh, C. E.

    2013-12-01

    Various granites in the Pan-African Neoproterozoic Fold Belt of Cameroon were investigated in an area around Ekomédion (southwestern Cameroon) in order to set constraints on their genesis and age. The studied granites were likely emplaced in relation with the Central Cameroon Shear Zone (CCSZ). Hence dating the granites provides an age for the dextral transcurrent tectonics event responsible for the CCSZ. The interest in these granitic rocks is spurred by noticeable Mo and U mineralization in a pegmatite that is hosted by two-mica granite. The studied granites comprise post-collisional syn-D4 two-mica granite, alkali-feldspar granite, biotite-rich granite and porphyritic granite. Based on lithogeochemical data, the granites can be characterized as ferroan, peraluminous and high-K calc-alkaline. The biotite-rich and alkali feldspar granites show I-type characteristics, whereas the porphyritic and two-mica granites reveal S-type affinity. All of them are marked by strong light rare earth element fractionation and a strong negative Eu anomaly, and they are strongly depleted in Ba, Nb, P, Sr and Ti, pointing to a crustal origin. Crust assimilation is also evident from zircon xenocrysts in the two-mica granite with upper intercept U-Pb ages of 2051 ± 44 Ma and 1550 ± 24 Ma. U-Pb dating of zircon, monazite and xenotime grains/domains yielded indistinguishable ages for both the two-mica granite (578 ± 4 Ma) and the porphyritic granite (579 ± 3 Ma). An identical age (578 ± 11 Ma) was obtained by Re-Os dating of molybdenite that occurs together with uraninite in pegmatite within the two-mica granite, thus clearly attesting to a late-magmatic origin of the ore. The studied granites have many similarities, both in composition and age, with granites in Nigeria and northeastern Brazil, supporting the continuation of a large Pan-African/Braziliano magmatic province from west-central Africa to northeastern Brazil.

  7. Associations between anxiety disorders, suicide ideation, and age in nationally representative samples of Canadian and American adults.

    PubMed

    Raposo, Sarah; El-Gabalawy, Renée; Erickson, Julie; Mackenzie, Corey S; Sareen, Jitender

    2014-12-01

    Suicidal behaviors are of significant concern for the individuals displaying such behavior and for service providers who encounter them. Using nationally representative samples of Canadian and American adults, we aimed to examine: whether age moderates the relationship between having any anxiety disorder and suicide ideation (SI), the prevalence of SI among younger and older adults, and whether age and individual anxiety disorders were differentially associated with SI. Age moderated the relationship between any anxiety disorder and SI among Americans only. Past-year SI was less prevalent among older, compared to younger, adults; though, nearly every anxiety disorder was associated with increased odds of SI among younger and older Canadian and American adults after controlling for covariates. Effect sizes were particularly large for older American adults, but were coupled with large confidence intervals. Findings contribute to a growing literature suggesting that SI in the context of anxiety is a highly prevalent and complex mental health problem across the adult lifespan. PMID:25306089

  8. When Do Laws Matter? National Minimum-Age-of-Marriage Laws, Child Rights, and Adolescent Fertility, 1989–2007

    PubMed Central

    Kim, Minzee; Longhofer, Wesley; Boyle, Elizabeth Heger; Nyseth, Hollie

    2014-01-01

    Using the case of adolescent fertility, we ask the questions of whether and when national laws have an effect on outcomes above and beyond the effects of international law and global organizing. To answer these questions, we utilize a fixed-effect time-series regression model to analyze the impact of minimum-age-of-marriage laws in 115 poor- and middle-income countries from 1989 to 2007. We find that countries with strict laws setting the minimum age of marriage at 18 experienced the most dramatic decline in rates of adolescent fertility. Trends in countries that set this age at 18 but allowed exceptions (for example, marriage with parental consent) were indistinguishable from countries that had no such minimum-age-of-marriage law. Thus, policies that adhere strictly to global norms are more likely to elicit desired outcomes. The article concludes with a discussion of what national law means in a diffuse global system where multiple actors and institutions make the independent effect of law difficult to identify. PMID:25525281

  9. A reappraisal of the age, origin and structural setting of sulphide mineralisation in the UK North Pennines Orefield

    NASA Astrophysics Data System (ADS)

    Holdsworth, Bob; Dempsey, Eddie; Selby, David; Le Cornu, Chris; Young, Brian

    2015-04-01

    The North Pennines Orefield (NPO) is centred on the Alston block, a structural high of fractured Carboniferous sedimentary rocks that unconformably overlie a Devonian age (ca. 399 Ma) granite pluton buried at shallow depths (<0.5 km). The orefield has long been considered to be a classic example of a Mississippi Valley Type (MVT) deposit where the source of the metals and sulphur are derived by hydrothermal leaching of the host sedimentary (carbonate-rich) rocks. The vein-hosted part of the orefield consists of linked systems of shear and tensile fractures with a variety of regionally recognised orientations (ESE-WNW Quarter Point, NE-SW, NW-SE Cross Veins). These are associated with lead (galena), iron (pyrite, pyrrhotite, marcasite), copper (chalcopyrite), zinc (sphalerite), fluorite, barite and quartz mineralization. New Rhenium-Osmium (Re-Os) isotope geochemical analysis of the vein-hosted pyrite mineralization suggests that: (i) the metalliferous ores of the NPO formed ca. 294Ma (earliest Permian); and (ii) that they carry an initial Os ratio indicative of a mantle source similar to that indicated by the initial Os ratio of the Whin Sill dolerite suite (emplacement ages ca. 297-294 Ma). New field observations and stress inversion analyses show that at least two regional deformation events are recognised in the Carboniferous host rocks of the NPO. A initial phase of Late Carboniferous ('Variscan') N-S compression pre-dates mineralisation and leads to formation of the NW-SE fractures, initiation of the Burtreeford Disturbance as a N-S fault and compressional reactivation of the previously extensional E-W Lunedale Fault. A later phase of dextral transtension (NNE-SSW extension, ESE-WNW compression) leads to the formation of the ESE-WNW and NE-SW veins, together with compressional reactivation of the Burtreeford Disturbance and Lunedale Fault. Field and microstructural analyses show that the transtensional deformation is synchronous with the main phases of NPO

  10. Origin and age of erosional gullies and ridges in loess of central Alaska--Evidence of ancient global warming

    SciTech Connect

    Pewe, T.L. . Geology Dept.)

    1992-01-01

    The lower and especially middle slopes of many of the rolling hills of the Yukon-Tanana Upland are blanketed with 3 to 20 m of olive gray, airfall, massive loess which is dissected by parallel gullies 10--15 m deep and 100--200 m long that trend downslope. The gullies and ridges occur over hundreds of square kilometers. It is believed the eroded and gullied loess topography originated during the last interglacial of 125 ka. The climatic warming led to: (1) melting of the ground ice in permafrost and thermokarst activity, and (2) to greatly reduced loess deposition. The author believes that most of the water to initiate loess cutting came from the melting of the great amount of ground ice in the permafrost. The last interglacial time was warm enough to melt the ground ice and initiate catastrophic thermokarst activity in easily erodible loess on hillsides. If the gullying had been in Holocene time, the ridges and gullies would be more sharp sided and the ridges relatively flat-topped, as is characteristic of trenched loess, even after centuries. On the other hand, gullies and ridges formed early during the Eva Interglacial would tend to be subdued by creep and solifluction during the 100,000 year Wisconsin cold interval. Such is illustrated by the downbending of loess and tephra on the sides of loess ridges. If the loess ridges were formed in Holocene time, they would include horizontal loess deposits of Wisconsin and perhaps early Holocene times inasmuch as they would be covering a nongullied topography. Examination reveals that there are no Wisconsin and Holocene loess deposits on the steep side slopes of the uppermost part of the ridges and other erosional remnants. The Subarctic Brown Forest soil is interglacial and, started to form anywhere from 10,000 to 8,000 years ago. The soil profile developed on the pre-soil ridge topography; therefore, the time of ridge and gully formation is pre-10,000 years.

  11. Dark-ages reionization & galaxy formation simulation VI: The origins and fate of the highest known redshift galaxy

    NASA Astrophysics Data System (ADS)

    Mutch, Simon J.; Liu, Chuanwu; Poole, Gregory B.; Geil, Paul M.; Duffy, Alan R.; Trenti, Michele; Oesch, Pascal A.; Illingworth, Garth D.; Mesinger, Andrei; Wyithe, J. Stuart B.

    2016-09-01

    Using Hubble data, including new grism spectra, Oesch et al. (2016) recently identified GN-z11, a MUV=-21.1 galaxy at z=11.1 (just 400 Myr after the Big Bang). With an estimated stellar mass of ˜109 M⊙, this galaxy is surprisingly bright and massive, raising questions as to how such an extreme object could form so early in the Universe. Using MERAXES, a semi-analytic galaxy formation model developed as part of the Dark-ages Reionization And Galaxy-formation Observables from Numerical Simulations (DRAGONS) programme, we investigate the potential formation mechanisms and eventual fate of GN-z11. The volume of our simulation is comparable to that of the discovery observations and possesses two analogue galaxies of similar luminosity to this remarkably bright system. Existing in the two most massive subhaloes at z=11.1 (Mvir=1.4× 1011 M⊙ and 6.7× 1010 M⊙), our model analogues show excellent agreement with all available observationally derived properties of GN-z11. Although they are relatively rare outliers from the full galaxy population at high-z, they are no longer the most massive or brightest systems by z=5. Furthermore, we find that both objects possess relatively smooth, but extremely rapid mass growth histories with consistently high star formation rates and UV luminosities at z > 11, indicating that their brightness is not a transient, merger driven feature. Our model results suggest that future wide-field surveys with JWST may be able to detect the progenitors of GN-z11 analogues out to z ˜13-14, pushing the frontiers of galaxy-formation observations to the early phases of cosmic reionization and providing a valuable glimpse of the first galaxies to reionize the Universe on large scales.

  12. Age, Growth and Reproduction of the Eastern Mudminnow (Umbra pygmaea) at the Great Swamp National Wildlife Refuge, New Jersey.

    USGS Publications Warehouse

    Panek, Frank; Weis, Judith S.

    2012-01-01

    Umbra pygmaea DeKay (Eastern Mudminnow) is one of four species of Umbridae in North America. There is little published life-history information on the species within its native range, particularly on age, growth, and reproduction. This study focuses on these aspects of the life history of this fish at the Great Swamp National Wildlife Refuge in Morris County, NJ. A total of 336 fish of seven species was collected from June 1978 through May 1979, with the Eastern Mudminnow comprising 74% of the total. The average annual growth increment in total length for the Eastern Mudminnow was 15.3 2.06 mm, with age-1 fish averaging 40 mm total length and age-5 fish, the oldest collected, averaging 107 mm total length. The length-weight relationship was log10W = -5.291 + 3.182 log10TL mm for males and log10W = -4.999 + 3.032 log10TL mm for females. We observed no statistically significant sexually dimorphic differences in length-weight relationships in this population. The ratio of females to males increased from a low of 0.6 (predominance of male fish) at age-1 to a high of 4.6 (predominance of females) at age-5. Annual mortality for age 2–5 fish ranged from 40–76% with a mean of 59 13%. Age-specific fecundity estimates ranged from 250 eggs/female at age-1 to 2168 eggs/female at age-5. The relationship of number of mature ova to age was best described by the exponential function y = 149.29e0.5287x, where y = age-specific fecundity and x = age in years. Ova ranged from 0.1–0.2 mm in diameter in June and July and averaged 1.41 0.1 mm (range = 1.29–1.62 mm) in early February prior to spawning. Peak spawning occurred in mid-April at temperatures of 9–12 °C, and all females were spent by late April (13–15 °C).

  13. Report on the United Nations World Assembly on Aging. Based on a Follow-Up Conference (Tampa, Florida, December 7, 1983).

    ERIC Educational Resources Information Center

    Briggs, Halaine-Sherin, Ed.

    This document reports the proceedings of a United Nations World Assembly on Aging follow-up conference. Presented are the following: "International Exchange Center on Gerontology: The Organization and Its Mission"; "Preface" (Sheppard); "Welcoming Telegram" (Shuman); "Overview of the World Assembly on Aging" (McDonald); "The Aging World" (Oriol);…

  14. Simulating the multicellular homeostasis with a cell-based discrete receptor dynamics model: The non-mutational origin of cancer and aging.

    PubMed

    Lou, Yuting; Chen, Yu

    2016-09-01

    The purpose of the study is to investigate the multicellular homeostasis in epithelial tissues over very large timescales. Inspired by the receptor dynamics of IBCell model proposed by Rejniak et al. an on-grid agent-based model for multicellular system is constructed. Instead of observing the multicellular architectural morphologies, the diversity of homeostatic states is quantitatively analyzed through a substantial number of simulations by measuring three new order parameters, the phenotypic population structure, the average proliferation age and the relaxation time to stable homeostasis. Nearby the interfaces of distinct homeostatic phases in 3D phase diagrams of the three order parameters, intermediate quasi-stable phases of slow dynamics that features quasi-stability with a large spectrum of relaxation timescales are found. A further exploration on the static and dynamic correlations among the three order parameters reveals that the quasi-stable phases evolve towards two terminations, tumorigenesis and degeneration, which are respectively accompanied by rejuvenation and aging. With the exclusion of the environmental impact and the mutational strategies, the results imply that cancer and aging may share the non-mutational origin in the intrinsic slow dynamics of the multicellular systems. PMID:27196967

  15. Parental age and risk of autism spectrum disorders in a Finnish national birth cohort.

    PubMed

    Lampi, Katja M; Hinkka-Yli-Salomäki, Susanna; Lehti, Venla; Helenius, Hans; Gissler, Mika; Brown, Alan S; Sourander, Andre

    2013-11-01

    Aim of the study was to examine the associations between parental age and autism spectrum disorders (ASD). Data were based on the FIPS-A (Finnish Prenatal Study of Autism and Autism Spectrum Disorders), a case-control study with a total of 4,713 cases with childhood autism (n = 1,132), Asperger's syndrome (n = 1,785) or other pervasive developmental disorder (PDD) (n = 1,796), which were ascertained from the Finnish Hospital Discharge Register. Controls were selected from the Finnish Medical Birth Register. Conditional logistic regression models were used for statistical analyses. Advanced paternal age (35-49 years) was associated with childhood autism in offspring, whereas advanced maternal age was associated with both Asperger's syndrome and PDD in offspring (35 years or more and 40 years or more, respectively). Teenage motherhood (19 years or less) was associated with PDD in offspring. The main finding was that maternal and paternal ages were differentially associated with ASD subtypes. In addition to advanced parental age, teenage pregnancy seems to incur a risk for PDD in offspring. PMID:23479075

  16. Radiation and mortality of workers at Oak Ridge National Laboratory: positive associations for doses received at older ages.

    PubMed Central

    Richardson, D B; Wing, S

    1999-01-01

    We examined associations between low-level exposure to ionizing radiation and mortality among 14,095 workers hired at the Oak Ridge National Laboratory between 1943 and 1972. Workers at the facility were individually monitored for external exposure to ionizing radiation and have been followed through 1990 to ascertain cause of death information. Positive associations were observed between low-level exposure to external ionizing radiation and mortality. These associations were larger for doses received after 45 years of age, larger under longer lag assumptions, and primarily due to cancer causes of death. All cancer mortality was estimated to increase 4.98% [standard error (SE) = 1.5] per 10-mSv cumulative dose received after age 45 under a 10-year lag, and 7.31% (SE = 2.2) per 10-mSv cumulative dose received after age 45 under a 20-year lag. Associations between radiation dose and lung cancer were of similar magnitude to associations between radiation dose and all cancers except lung cancer. Nonmalignant respiratory disease exhibited a positive association with cumulative radiation dose received after age 45, whereas ischemic heart disease exhibited no association with radiation dose. These findings suggest increases in cancer mortality associated with low-level external exposure to ionizing radiation and potentially greater sensitivity to the carcinogenic effects of ionizing radiation with older ages at exposure. Images Figure 1 PMID:10417363

  17. The Hierarchical Factor Model of ADHD: Invariant across Age and National Groupings?

    ERIC Educational Resources Information Center

    Toplak, Maggie E.; Sorge, Geoff B.; Flora, David B.; Chen, Wai; Banaschewski, Tobias; Buitelaar, Jan; Ebstein, Richard; Eisenberg, Jacques; Franke, Barbara; Gill, Michael; Miranda, Ana; Oades, Robert D.; Roeyers, Herbert; Rothenberger, Aribert; Sergeant, Joseph; Sonuga-Barke, Edmund; Steinhausen, Hans-Christoph; Thompson, Margaret; Tannock, Rosemary; Asherson, Philip; Faraone, Stephen V.

    2012-01-01

    Objective: To examine the factor structure of attention-deficit/hyperactivity disorder (ADHD) in a clinical sample of 1,373 children and adolescents with ADHD and their 1,772 unselected siblings recruited from different countries across a large age range. Hierarchical and correlated factor analytic models were compared separately in the ADHD and…

  18. 75 FR 54890 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-09

    ... Panel; Aminergic Function in Brain Aging and Alzheimer's Disease. Date: October 19, 2010. Time: 12 p.m... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  19. Cross-national comparison of disability in Latin American and Caribbean persons aged 75 and older.

    PubMed

    Reyes-Ortiz, Carlos A; Ostir, Glenn V; Pelaez, Martha; Ottenbacher, Kenneth J

    2006-01-01

    The objectives of this study were to compare rates of instrumental activity of daily living (IADL) and activity of daily living (ADL) difficulties and examine sociodemographic and health correlates of IADL and ADL difficulties. Data were extracted from the first interview of Health, Well-Being and Aging in Latin America and the Caribbean Study (abbreviated from Spanish name as: SABE = salud, bienestar y envejecimiento en America Latina y el Caribe). This analysis included 3225 subjects aged 75 and older living in seven capital cities during 1999-2000. Reporting either IADL or ADL difficulties were the outcomes. Bivariate and multiple logistic regression analyses were used to examine the associations between IADL or ADL difficulties and sociodemographics, and health characteristics. The highest prevalence of IADL difficulties was reported in Sao Paulo (33.8%) and the lowest in Montevideo (12.0%). The highest prevalence of ADL difficulties was reported in Santiago (34.7%) and the lowest in Bridgetown (16.9%). In a combined analysis across cities, increased age, fewer years of education, lower body mass index (BMI) (<20), and high number of medical conditions were independently significantly associated with IADL and ADL difficulties. In conclusion, about a third of persons aged 75 and older reported difficulty in at least one IADL or ADL. There was a wide variation on disability rates and correlates across cities. PMID:16126289

  20. Cosmogenic 10Be Exposure Age for the Cut Bank Creek terminal moraine, Glacier National Park, MT

    NASA Astrophysics Data System (ADS)

    Quirk, B.; Laabs, B. J.; Leonard, E. M.; Caffee, M. W.

    2012-12-01

    Mountain glaciers are highly sensitive to temperature and precipitation with geologic records that are superb proxies of climate change. In the Rocky Mountains of the western United States, abundant records of Late Pleistocene glaciation provide an opportunity for understanding paleoclimate throughout this region, especially in places where the chronology of glaciation is precisely known. Cosmogenic 10Be exposure dating has been widely applied to glacial deposits in the Rocky Mountains, providing precise numerical ages and improving the understanding of glacial chronologies in this region. Despite these improvements, the chronology of the last Pleistocene glaciation of the northernmost Rocky Mountains is not completely understood. Cosmogenic 10Be exposure dating was applied to the Cut Bank Creek valley in the Lewis Range of the Northern Rocky Mountains, where a discrete mountain glacier deposited a broad terminal moraine during the last Pleistocene glaciation. Exposure ages of eight quartzite and sandstone boulders at the crest of the ice-distal sector of the terminal moraine indicate that abandonment occurred at 15.6 ± 0.8 ka. This age is consistent with age limits of several terminal moraines elsewhere in the Northern Rocky Mountains, suggesting that the last Pleistocene glaciation culminated in this region after the global Last Glacial Maximum.

  1. Suicide Attempts in Israel: Age by Gender Analysis of a National Emergency Departments Database

    ERIC Educational Resources Information Center

    Levinson, Daphna; Haklai, Ziona; Stein, Nechama; Gordon, Ethel-Sherry

    2006-01-01

    An analysis of all emergency department admissions in Israel classified as an attempted suicide in the years 1996-2002 was done to examine attempted suicide rates by age and gender with particular attention to adolescents and young adults. Gender differences in attempted suicide rates were significant only during adolescence and young adulthood,…

  2. Childhood Risk Factors for Lifetime Anorexia Nervosa by Age 30 Years in a National Birth Cohort

    ERIC Educational Resources Information Center

    Nicholls, Dasha E.; Viner, Russell M.

    2009-01-01

    Whether previously identified childhood risk factors for anorexia nervosa (AN) predict self-reported lifetime AN by age 30 is examined. The cohort confirmed four risk and two protective factors out of the 22 suggested risk factors. The study used data from the 1970 British Cohort Study.

  3. Language, Literacy and Numeracy in National Training Packages: Case Studies in Aged Care and Hospitality.

    ERIC Educational Resources Information Center

    Haines, Christine; Brand, Jennie Bickmore

    The implementation and effectiveness of the inclusion of literacy and numeracy in industry training packages was examined in case studies of three programs in Western Australia. Two were certificate programs in cooking and food and beverage as specified in the hospitality training package, and the third was an aged care program based on the…

  4. Age, sex, and racial differences in harsh physical punishment: results from a nationally representative United States sample.

    PubMed

    Taillieu, Tamara L; Afifi, Tracie O; Mota, Natalie; Keyes, Katherine M; Sareen, Jitender

    2014-12-01

    The purpose of this research was to examine age, sex, and racial differences in the prevalence of harsh physical punishment in childhood in a nationally representative sample of the United States. Data were from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) collected in 2004 and 2005 (n=34,653). Logistic regression analyses were conducted to examine age, sex, and racial differences in the prevalence of harsh physical punishment. Results suggest that the prevalence of harsh physical punishment has been decreasing among more recently born age groups; however, there appear to be sex and racial differences in this trend over time. The magnitude of the decrease appears to be stronger for males than for females. By race, the decrease in harsh physical punishment over time is only apparent among Whites; Black participants demonstrate little change over time, and harsh physical punishment seems to be increasing over time among Hispanics. Prevention and intervention efforts that educate about the links of physical punishment to negative outcomes and alternative non-physical discipline strategies may be particularly useful in reducing the prevalence of harsh physical punishment over time. PMID:25466426

  5. Age, sex, and racial differences in harsh physical punishment: Results from a nationally representative United States sample

    PubMed Central

    Taillieu, Tamara L.; Afifi, Tracie O.; Mota, Natalie; Keyes, Katherine M.; Sareen, Jitender

    2015-01-01

    The purpose of this research was to examine age, sex, and racial differences in the prevalence of harsh physical punishment in childhood in a nationally representative sample of the United States. Data were from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) collected in 2004 and 2005 (n = 34,653). Logistic regression analyses were conducted to examine age, sex, and racial differences in the prevalence of harsh physical punishment. Results suggest that the prevalence of harsh physical punishment has been decreasing among more recently born age groups; however, there appear to be sex and racial differences in this trend over time. The magnitude of the decrease appears to be stronger for males than for females. By race, the decrease in harsh physical punishment over time is only apparent among Whites; Black participants demonstrate little change over time, and harsh physical punishment seems to be increasing over time among Hispanics. Prevention and intervention efforts that educate about the links of physical punishment to negative outcomes and alternative non-physical discipline strategies may be particularly useful in reducing the prevalence of harsh physical punishment over time. PMID:25466426

  6. Prevalence, awareness, treatment, and control of hypertension in the older population: results from the multiple national studies on ageing.

    PubMed

    Yang, Fan; Qian, Dongfu; Hu, Dan

    2016-02-01

    The international comparisons that provided useful epidemiologic information of hypertension in the elderly people is still sparse; we aim to provide the latest international estimates on the burden of hypertension. These sampling methods of the selection of surveys mainly used multistage population registry; this cross-national study of 63,014 adults aged ≥50 years was from in four high-income countries, four upper-middle-income countries (UMICs), and three low-middle-income countries (LMICs). Overall, the age-standardized prevalence of hypertension among the adult population aged ≥50 years was 53.2% (51.9% of men and 54.3% of women). The high-income countries and UMICs had more or less twice the prevalence of hypertension compare with LMICs. The rates of awareness, treatment, and control of hypertension were 55.6%, 44.1%, and 17.1%, respectively, and awareness and control of hypertension were lowest in UMICs and treatment of hypertension was lowest in LMICs. Among this multiple national study population, hypertension was very common among elderly population. Even more worrisome is that the rates of awareness, treatment, and control of hypertension were relatively low in UMICs and IMICs. These results indicate that improving the ability to control and prevention of hypertension in resource-limited settings is needed. PMID:26778770

  7. The Development of Cognitive, Language, and Cultural Skills from Age 3 to 6: A Comparison between Children of Turkish Origin and Children of Native-Born German Parents and the Role of Immigrant Parents' Acculturation to the Receiving Society

    ERIC Educational Resources Information Center

    Becker, Birgit; Klein, Oliver; Biedinger, Nicole

    2013-01-01

    This article analyzes the longitudinal development of differences in academic skills between children of Turkish origin and children of native-born German parents from age 3 to 6 in Germany with a focus on the role of immigrant parents' acculturation to the receiving society. Growth curve models show that Turkish-origin children start with lower…

  8. School and Nation: Identity Politics and Educational Media in an Age of Diversity

    ERIC Educational Resources Information Center

    Carrier, Peter, Ed.

    2013-01-01

    At a time when the power of schools and both state and federal education authorities to guide young people's sense of belonging is being challenged by multilingualism, by the claims of supra- and subnational regions and minorities, by memories of national catastrophes and crimes, and by out-of-school educational media, this collection of essays…

  9. The National Center for Community Education: On the Threshold of a New Age.

    ERIC Educational Resources Information Center

    Krajewski, Fran; Osowski, Val

    1997-01-01

    The Charles Stewart Mott Foundation has been involved in the community-school/community-education movement since the 1935 Flint Community Schools (Michigan) experiment led to fuller use of local school facilities for learning and recreation programs. The National Center for Community Education (NCCE) was established in the 1960s as a training…

  10. Literacy in Malta: The National Literacy Survey of Year 5 Pupils (Aged 9-10)

    ERIC Educational Resources Information Center

    Mifsud, Charles; Grech, Rowena; Hutchison, Dougal; Morrison, Jo

    2005-01-01

    The work reported here is based on the second Malta National Literacy Survey, carried out in March 2002. All Year 5 pupils in Malta were involved and their literacy attainment in both Maltese and English was tested. Two parallel multi-level analyses were carried out, one for Maltese, the other for English. The background variables were; gender,…

  11. Who Uses Services for School Age Children: Evidence from the National Evaluation of the Children's Fund

    ERIC Educational Resources Information Center

    Leone, Tiziana; Plewis, Ian

    2008-01-01

    The UK government has made integration of services for children a priority with the target being a better and more integrated provision of preventative services under the various schemes such as the Children's Fund and Sure Start. This article gathers evidence from the National Evaluation of the Children Fund with the aim of analysing the…

  12. Informing the Nation. Federal Information Dissemination in an Electronic Age. Summary.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Office of Technology Assessment.

    This report summarizes a study conducted by the Office of Technology Assessment which addressed the opportunities offered by technological advances to improve the dissemination of federal information essential to public understanding of many issues facing Congress and the Nation. Two major problems are highlighted: maintaining equity in public…

  13. Affective Norms for 4900 Polish Words Reload (ANPW_R): Assessments for Valence, Arousal, Dominance, Origin, Significance, Concreteness, Imageability and, Age of Acquisition

    PubMed Central

    Imbir, Kamil K.

    2016-01-01

    In studies that combine understanding of emotions and language, there is growing demand for good-quality experimental materials. To meet this expectation, a large number of 4905 Polish words was assessed by 400 participants in order to provide a well-established research method for everyone interested in emotional word processing. The Affective Norms for Polish Words Reloaded (ANPW_R) is designed as an extension to the previously introduced the ANPW dataset and provides assessments for eight different affective and psycholinguistic measures of Valence, Arousal, Dominance, Origin, Significance, Concreteness, Imageability, and subjective Age of Acquisition. The ANPW_R is now the largest available dataset of affective words for Polish, including affective scores that have not been measured in any other dataset (concreteness and age of acquisition scales). Additionally, the ANPW_R allows for testing hypotheses concerning dual-mind models of emotion and activation (origin and subjective significance scales). Participants in the current study assessed all 4905 words in the list within 1 week, at their own pace in home sessions, using eight different Self-assessment Manikin (SAM) scales. Each measured dimension was evaluated by 25 women and 25 men. The ANPW_R norms appeared to be reliable in split-half estimation and congruent with previous normative studies in Polish. The quadratic relation between valence and arousal was found to be in line with previous findings. In addition, nine other relations appeared to be better described by quadratic instead of linear function. The ANPW_R provides well-established research materials for use in psycholinguistic and affective studies in Polish-speaking samples. PMID:27486423

  14. Preliminary insight into the age and origin of the Labeobarbus fish species flock from Lake Tana (Ethiopia) using the mtDNA cytochrome b gene.

    PubMed

    de Graaf, Martin; Megens, Hendrik-Jan; Samallo, Johannis; Sibbing, Ferdinand

    2010-02-01

    The high diversity of Cyprinid fish in Ethiopia's Lake Tana appears to be an example of ecological differentiation and assortative mating leading to rapid sympatric speciation. Lake Tana's Labeobarbus species flock consists of 15 morphological and ecological distinct species. This is the first attempt to determine the age and origin and inter-species relationships of Lake Tana's Labeobarbus species using the mtDNA cytochrome b gene. Analysis of cytchrome b sequences shows that Lake Tana's species flock appears to be young but the present dataset did not unequivocally support monophyly of Lake Tana's species. Additional markers are needed to determine whether Lake Tana's labeobarbs originated from a single or multiple incursion(s) of ancestral L. intermedius in the Lake Tana drainage basin, or the disruption of an ancient continuous riverine population by the emergence of the Tissisat waterfalls. Adaptive radiation and speciation within Lake Tana's Labeobarbus species flock may have occurred in the last 10,000-25,000years, following the desiccation of Lake Tana around 17,000years ago, at the same time as Lake Victoria, however, obtaining more data using other (nuclear) markers is urgently required. PMID:19878730

  15. [Violence in old age: the issue addressed in indexed national journals].

    PubMed

    de Castro, Anúbes Pereira; Guilam, Maria Cristina Rodrigues; Sousa, Eduardo Sérgio Soares; Marcondes, Willer Baumgarten

    2013-05-01

    One of the consequences of increased life expectancy is the increase in the elderly population in many countries, including Brazil. Considering the vulnerability of this age group and the increasing prevalence of violence against the elderly, there is a pressing need for research and control interventions to minimize the phenomenon. This exploratory and descriptive article conducts an analysis into this topic in indexed Brazilian studies in SciELO, with special emphasis on the last five years. The themes were categorized into: Social construction and conceptualizations, 37.5%; Elderly Care and Protection Policies, 43.75%; and Typology of violence against the elderly, 18.75%. The results show that the Policy of protection of the elderly permeates the majority of discussions about violence in old age and the focus of the researchers' attention is on domestic violence, which needs to be broadened in field research. PMID:23670456

  16. Exploring the relationship between national economic indicators and relative fitness and frailty in middle-aged and older Europeans

    PubMed Central

    Theou, Olga; Brothers, Thomas D.; Rockwood, Michael R.; Haardt, David; Mitnitski, Arnold; Rockwood, Kenneth

    2013-01-01

    Background: on an individual level, lower-income has been associated with disability, morbidity and death. On a population level, the relationship of economic indicators with health is unclear. Objective: the purpose of this study was to evaluate relative fitness and frailty in relation to national income and healthcare spending, and their relationship with mortality. Design and setting: secondary analysis of data from the Survey of Health, Ageing and Retirement in Europe (SHARE); a longitudinal population-based survey which began in 2004. Subjects: a total of 36,306 community-dwelling people aged 50 and older (16,467 men; 19,839 women) from the 15 countries which participated in the SHARE comprised the study sample. A frailty index was constructed as the proportion of deficits present in relation to the 70 deficits available in SHARE. The characteristics of the frailty index examined were mean, prevalence of frailty and proportion of the fittest group. Results: the mean value of the frailty index was lower in higher-income countries (0.16 ± 0.12) than in lower-income countries (0.20 ± 0.14); the overall mean frailty index was negatively correlated with both gross domestic product (r = −0.79; P < 0.01) and health expenditure (r = −0.63; P < 0.05). Survival in non-frail participants at 24 months was not associated with national income (P = 0.19), whereas survival in frail people was greater in higher-income countries (P < 0.05). Conclusions: a country's level of frailty and fitness in adults aged 50+ years is strongly correlated with national economic indicators. In higher-income countries, not only is the prevalence of frailty lower, but frail people also live longer. PMID:23443511

  17. Saint-Gaudens National Historic Site: Home of a Gilded Age Icon. Teaching with Historic Places.

    ERIC Educational Resources Information Center

    Percoco, James A.

    Augustus Saint-Gaudens (1848-1907) was a renowned 19th-century U.S. sculptor whose artistic training and talent ensured his place in Gilded Age society. In 1885, he was drawn to Cornish, New Hampshire, to find a place where he could model his latest commission, a statue of Abraham Lincoln. He and his wife established a summer home and studio in an…

  18. Parental Age and Risk of Autism Spectrum Disorders in a Finnish National Birth Cohort

    ERIC Educational Resources Information Center

    Lampi, Katja M.; Hinkka-Yli-Salomäki, Susanna; Lehti, Venla; Helenius, Hans; Gissler, Mika; Brown, Alan S.; Sourander, Andre

    2013-01-01

    Aim of the study was to examine the associations between parental age and autism spectrum disorders (ASD). Data were based on the FIPS-A (Finnish Prenatal Study of Autism and Autism Spectrum Disorders), a case-control study with a total of 4,713 cases with childhood autism (n = 1,132), Asperger's syndrome (n = 1,785) or other pervasive…

  19. Early adulthood: an overlooked age group in national sodium reduction initiatives in South Korea

    PubMed Central

    Park, Sohyun; Lee, Jounghee; Kwon, Kwang-Il; Kim, Jong-Wook; Byun, Jae-Eon; Kang, Baeg-Won; Choi, Bo Youl

    2014-01-01

    BACKGROUND/OBJECTIVES South Korean's sodium consumption level is more than twice the upper limit level suggested by the WHO. Steep increases in the prevalence of hypertension and cardiovascular disease in Korea necessitate more effective sodium reduction programs. This study was conducted in order to compare sodium intake-related eating behaviors and key psychosocial factors according to age group and gender. SUBJECTS/METHODS Using an online survey, a total of 1,564 adults (20-59 years old) considered to be geographically representative of South Korea were recruited and surveyed. The major outcomes were perceived behaviors, knowledge, intentions, and self-efficacy related to sodium intake. RESULTS The results show that perceived behavior and level of self-efficacy related to low sodium consumption differed by age and gender. Female participants showed better behavior and intention towards low sodium intake than male counterparts. Young participants in their 20s showed the lowest intention to change their current sodium intake as well as lowest self-efficacy measures. CONCLUSIONS Future sodium reduction interventions should be developed with tailored messages targeting different age and gender groups. Specifically, interventions can be planned and implemented at the college level or for workers in their early career to increase their intention and self-efficacy as a means of preventing future health complications associated with high sodium intake. PMID:25489413

  20. Do gender and age moderate the symptom structure of PTSD? Findings from a national clinical sample of children and adolescents.

    PubMed

    Contractor, Ateka A; Layne, Christopher M; Steinberg, Alan M; Ostrowski, Sarah A; Ford, Julian D; Elhai, Jon D

    2013-12-30

    A substantial body of evidence documents that the frequency and intensity of posttraumatic stress disorder (PTSD) symptoms are linked to such demographic variables as female sex (e.g., Kaplow et al., 2005) and age (e.g., Meiser-Stedman et al., 2008). Considerably less is known about relations between biological sex and age with PTSD's latent factor structure. This study systematically examined the roles that sex and age may play as candidate moderators of the full range of factor structure parameters of an empirically supported five-factor PTSD model (Elhai et al., 2011). The sample included 6591 trauma-exposed children and adolescents selected from the National Child Traumatic Stress Network's Core Data Set. Confirmatory factor analysis using invariance testing (Gregorich, 2006) and comparative fit index difference values (Cheung and Rensvold, 2002) reflected a mixed pattern of test item intercepts across age groups. The adolescent subsample produced lower residual error variances, reflecting less measurement error than the child subsample. Sex did not show a robust moderating effect. We conclude by discussing implications for clinical assessment, theory building, and future research. PMID:24103907

  1. National sample survey organization survey report: An estimation of prevalence of mental illness and its association with age in India

    PubMed Central

    Lakhan, Ram; Ekúndayò, Olúgbémiga T.

    2015-01-01

    Background: The Indian population suffers with significant burden of mental illness. The prevalence rate and its association with age and other demographic indicators are needed for planning purpose. Objective: This study attempted to calculate age-wise prevalence of mental illness for rural and urban settings, and its association with age. Materials and Methods: Data published in National Sample Survey Organization (2002) report on disability is used for the analysis. Spearman correlation for strength of association, z-test for difference in prevalence, and regression statistics for predicting the prevalence rate of mental illness are used. Result: Overall population have 14.9/1000 prevalence of mental illness. It is higher in rural setting 17.1/1000 than urban 12.7/1000 (P < 0.001). There is a strong correlation found with age in rural (ϱ = 0.910, P = 0.001) and urban (ϱ = 0.940, P = 0.001). Conclusion: Results of this study confirm other epidemiological research in India. Large-population epidemiological studies are recommended. PMID:25552851

  2. Petrography, age, and paleomagnetism of basaltic lava flows in coreholes at Test Area North (TAN), Idaho National Engineering Laboratory

    SciTech Connect

    Lanphere, M.A.; Champion, D.E.; Kuntz, M.A.

    1994-12-31

    The petrography, age, and paleomagnetism were determined on basalt from 21 lava flows comprising about 1,700 feet of core from two coreholes (TAN CH No. 1 and TAN CH No. 2) in the Test Area North (TAN) area of the Idaho National Engineering Laboratory (INEL). Paleomagnetic studies were made on two additional cores from shallow coreholes in the TAN area. K-Ar ages and paleomagnetism also were determined on nearby surface outcrops of Circular Butte. Paleomagnetic measurements were made on 416 samples from four coreholes and on a single site in surface lava flows of Circular Butte. K-Ar ages were measured on 9 basalt samples from TAN CH No. 1 and TAN CH No. 2 and one sample from Circular Butte. K-Ar ages ranged from 1.044 Ma to 2.56 Ma. All of the samples have reversed magnetic polarity and were erupted during the Matuyama Reversed Polarity Epoch. The purpose of investigations was to develop a three-dimensional stratigraphic framework for geologic and hydrologic studies including potential volcanic hazards to facilities at the INEL and movement of radionuclides in the Snake River Plain aquifer.

  3. Origins, Chronology, and Current Status of the National Research Center for Career and Technical Education: 1963-2012

    ERIC Educational Resources Information Center

    Lewis, Morgan V.; Stone, James R., III

    2013-01-01

    The National Research Center for Career and Technical Education (NRCCTE) had a unique status among federally funded research and development center in education. Its funding was authorized by the federal legislation for career and technical and administered by the Office of Vocational and Adult Education, not the Institute for Education Sciences.…

  4. The Status of the Black Elderly in the United States. A Report by the National Caucus and Center on Black Aged, Inc., for the Select Committee on Aging. House of Representatives, One Hundredth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This report on the status of the black elderly in the United States is based on six issue forums that the National Caucus and Center on Black Aged, Inc., conducted throughout the United States in 1986; and on three House Select Committee on Aging hearings on this subject. Statistics pertaining to the following issues affecting older blacks are…

  5. Ages of travertine deposits in eastern Grand Canyon National Park, Arizona

    USGS Publications Warehouse

    Szabo, B. J.

    1990-01-01

    Travertine deposits in eastern Grand Canyon National Park, Arizona, are inferred to have formed under conditions of effective wetness that were greater than present. Uranium-series dating of 17 samples indicates that the deposits formed at about 15,000, 71,000, 111,000, 171,000, and 338,000 yr B.P. Intervals of travertine deposition are essentially contemporaneous with dated high paleolake levels, montane glacial maxima, and high paleowater-table levels from several Great Basin localities. ?? 1990.

  6. The origins of the Federal Republic of Germany's space policy, 1959-1965: European and national dimensions

    NASA Astrophysics Data System (ADS)

    Fischer, Peter

    1994-01-01

    The ESA History Study Reports are preliminary reports of studies carried out within the framework of an ESA (European Space Agency) contract. They will form the basis of a comprehensive study of European Space activities covering the period 1959-1987. The impressive, yet somewhat shady, political past of space research in Germany is discussed in this report. Germany's participation in the initial program of ELDO served to start an ambitious national space program denied to the country since 1945, first by allied prohibitions and then, after 1955, by self-exercised political restraints. German membership in ESRO and ELDO had the advantage that the Federal government would be locked into a structure from which it was extremely difficult to withdraw. Since any successful participation in these international organizations depended on the rapid national build-up of technological know-how and a functioning industrial and scientific infrastructure, the commitment for the Federal government to promote a national space program in parallel was an immediate consequence of the decision to join ESRO and ELDO. This assessment rapidly bore fruit and the Federal Republic soon became one of the major European space powers.

  7. Age, actuarial risk, and long-term recidivism in a national sample of sex offenders.

    PubMed

    Nicholaichuk, Terry P; Olver, Mark E; Gu, Deqiang; Wong, Stephen C P

    2014-10-01

    Age at release has become an increasing focus of study with regard to evaluating risk in the sex offender population and has been repeatedly shown to be an important component of the risk assessment equation. This study constitutes an extension of a study of sex offender outcomes prepared for the Evaluation Branch, Correctional Service of Canada. The entire cohort of 2,401 male federally incarcerated sexual offenders who reached their warrant expiry date (WED) within 1997/1998, 1998/1999, and 1999/2000 fiscal years were reviewed for the study. Sexual and violent reconviction information was obtained from CPIC criminal records over an average of 12.0 years (SD = 1.7) follow-up. This study focused upon the cohort of sex offenders who were 50 years or older at time of release (N = 542). They were stratified according to risk using a brief actuarial scale (BARS) comprising six binary variables. For the most part, older offenders showed low base rates of sexual recidivism regardless of the risk band into which they fell. The exception was a small group of elderly offenders (n = 20) who fell into the highest risk band, and who showed high levels of sexual recidivism. The results of this combination of cross-sectional and longitudinal analyses of elderly sexual offenders may have important implications for offender management, particularly in light of the increasing numbers of offenders in Canada who fall into the over 50 age cohort. PMID:23818657

  8. Age, fertility and reproductive behavior in cuban crocodiles, Crocodylus rhombifer, at the Smithsonian's National Zoological Park.

    PubMed

    Augustine, Lauren; Watkins, Barbara

    2015-01-01

    The Smithsonian's National Zoological Park (NZP) has a long history with Cuban crocodiles, Crocodylus rhombifer, beginning in 1900's when the first animals arrived at the NZP. Today, the Zoo has two breeding groups of C. rhombifer and has observed and analyzed reproductive behavior and fertility rates over the last three years. Fertility rates were determined initially by observing the formation of an opaque band that forms on the shell of a fertile egg, called banding. The fertility rates by banding were later compared to the observation made after opening the eggs to verify fertility. In addition to tracking fertility, nesting and agonistic behavior were also observed. Several notable observations were documented over the same period. These included a male predating a nesting female's eggs, increased aggression between two females housed together, the continued development of a partially banded egg, and the discovery of 19 additional egg shells post oviposition by both females in the enclosure. Here we discuss the nest phenology, fertility and behavior of the five exhibited C. rhombifer at the Smithsonian's National Zoological Park over a 3-year period. Zoo Biol. 34:278-284, 2015. © 2015 Wiley Periodicals Inc. PMID:25716550

  9. Aspen Ecology in Rocky Mountain National Park: Age Distribution, Genetics, and the Effects of Elk Herbivory

    SciTech Connect

    Tuskan, Gerald A; Yin, Tongming

    2008-10-01

    Lack of aspen (Populus tremuloides) recruitment and canopy replacement of aspen stands that grow on the edges of grasslands on the low-elevation elk (Cervus elaphus) winter range of Rocky Mountain National Park (RMNP) in Colorado has been a cause of concern for more than 70 years (Packard, 1942; Olmsted, 1979; Stevens, 1980; Hess, 1993; R.J. Monello, T.L. Johnson, and R.G. Wright, Rocky Mountain National Park, 2006, written commun.). These aspen stands are a significant resource since they are located close to the park's road system and thus are highly visible to park visitors. Aspen communities are integral to the ecological structure of montane and subalpine landscapes because they contain high native species richness of plants, birds, and butterflies (Chong and others, 2001; Simonson and others, 2001; Chong and Stohlgren, 2007). These low-elevation, winter range stands also represent a unique component of the park's plant community diversity since most (more than 95 percent) of the park's aspen stands grow in coniferous forest, often on sheltered slopes and at higher elevations, while these winter range stands are situated on the low-elevation ecotone between the winter range grasslands and some of the park's drier coniferous forests.

  10. Excess mortality in women of reproductive age from low-income countries: a Swedish national register study

    PubMed Central

    Haglund, Bengt; Högberg, Ulf; Essén, Birgitta

    2013-01-01

    Background: Cause-of-death statistics is widely used to monitor the health of a population. African immigrants have, in several European studies, shown to be at an increased risk of maternal death, but few studies have investigated cause-specific mortality rates in female immigrants. Methods: In this national study, based on the Swedish Cause of Death Register, we studied 27 957 women of reproductive age (aged 15–49 years) who died between 1988 and 2007. Age-standardized mortality rates per 100 000 person years and relative risks for death and underlying causes of death, grouped according to the International Statistical Classification of Diseases and Related Health Problems, 10th Revision, were calculated and compared between women born in Sweden and in low-, middle- and high-income countries. Results: The total age-standardized mortality rate per 100 000 person years was significantly higher for women born in low-income (84.4) and high-income countries (83.7), but lower for women born in middle-income countries (57.5), as compared with Swedish-born women (68.1). The relative risk of dying from infectious disease was 15.0 (95% confidence interval 10.8–20.7) and diseases related to pregnancy was 6.6 (95% confidence interval 2.6–16.5) for women born in low-income countries, as compared to Swedish-born women. Conclusions: Women born in low-income countries are at the highest risk of dying during reproductive age in Sweden, with the largest discrepancy in mortality rates seen for infectious diseases and diseases related to pregnancy, a cause of death pattern similar to the one in their countries of birth. The World Bank classification of economies may be a useful tool in migration research. PMID:22850186

  11. Measuring Cognition: The Chicago Cognitive Function Measure in the National Social Life, Health and Aging Project, Wave 2

    PubMed Central

    Sunkara, Priya D.; Kotwal, Ashwin; Kern, David W.; Henning, Sara L.; McClintock, Martha K.; Schumm, Philip; Waite, Linda J.; Dale, William

    2014-01-01

    Objectives. To describe the development of a multidimensional test of cognition for the National Social life, Health and Aging Project (NSHAP), the Chicago Cognitive Function Measure (CCFM). Method. CCFM development included 3 steps: (a) A pilot test of the Montreal Cognitive Assessment (MoCA) to create a standard protocol, choose specific items, reorder items, and improve clarity; (b) integration into a CAPI-based format; and (c) evaluation of the performance of the CCFM in the field. The CCFM was subsequently incorporated into NSHAP, Wave 2 (n = 3,377). Results. The pre-test (n = 120) mean age was 71.35 (SD 8.40); 53% were female, 69% white, and 70% with college or greater education. The MoCA took an average of 15.6min; the time for the CCFM was 12.0min. CCFM scores (0–20) can be used as a continuous outcome or to adjust for cognition in a multivariable analysis. CCFM scores were highly correlated with MoCA scores (r = .973). Modeling projects MoCA scores from CCFM scores using the equation: MoCA = (1.14 × CCFM) + 6.83. In Wave 2, the overall weighted mean CCFM score was 13.9 (SE 0.13). Discussion. A survey-based adaptation of the MoCA was successfully integrated into a nationally representative sample of older adults, NSHAP Wave 2. PMID:25360018

  12. Age of ground water in basalt aquifers near Spring Creek National Fish Hatchery, Skamania County, Washington

    USGS Publications Warehouse

    Hinkle, Stephen R.

    1996-01-01

    A comparison of CFC data with both adjusted and unadjusted 14C data suggests that water discharging at the hatchery springs contains a mixture of modem and old water, where old water is defined as water recharged prior to 1944. The CFC data support a component of modem water, whereas the 14C data suggest a component of old water. Similar results were obtained from a comparison of CFC data with adjusted and unadjusted 14C data for water collected from Well 3. Well 3 is north of the hatchery springs, on a flow path that appears to be parallel to and similar in length to the flow path leading to the hatchery springs. Water from the Hatchery Well, however, may be devoid of modem water and appears to have an overall age on the order of thousands of years.

  13. A Nation of Immigrants: Assimilation and Economic Outcomes in the Age of Mass Migration

    PubMed Central

    Abramitzky, Ran; Boustan, Leah Platt; Eriksson, Katherine

    2015-01-01

    During the Age of Mass Migration (1850–1913), the United States maintained an open border, absorbing 30 million European immigrants. Prior cross-sectional work finds that immigrants initially held lower-paid occupations than natives but converged over time. In newly assembled panel data, we show that, in fact, the average immigrant did not face a substantial occupation-based earnings penalty upon first arrival and experienced occupational advancement at the same rate as natives. Cross-sectional patterns are driven by biases from declining arrival cohort skill level and departures of negatively selected return migrants. We show that assimilation patterns vary substantially across sending countries and persist in the second generation. PMID:26609186

  14. The FAA`s Aging Aircraft Nondestructive Inspection Validation Center at Sandia National Laboratories: An introduction

    SciTech Connect

    Walter, P.

    1995-07-01

    In these times of budget tightening for both government and private industry, this issue of Materials Evaluation is devoted to describing a cooperative relationship leveraging resources in the Department of Transportation`s Federal Aviation Administration (FAA) and the Department of Energy`s Sandia National Laboratories. This relationship resulted in a facility whose purpose is to assess technologies intended to enhance the reliability and cost effectiveness of inspection in the civil aviation industry. Eight articles are presented to describe this facility and its related activities. The center, located at the Albuquerque International Airport, has as its mission assessing and -- where justified -- encouraging the transfer of emerging inspection technologies to the civil aviation industry.

  15. Application of the hypothesis of Developmental Origin of Health and Diseases (DOHaD) in epidemiological studies of women at reproductive age and pregnant women in Poland.

    PubMed

    Wojtyła, Andrzej

    2011-01-01

    Epidemiological population studies indicate that the nutrition of women at reproductive age and during pregnancy exerts an eff ect not only on the term of delivery, development of the foetus and birth weight, but also on the susceptibility of off spring to civilization diseases in adulthood, according to the hypothesis of Developmental Origin of Heath and Diseases (DOHaD). The author analyses the results of epidemiological studies conducted in 2011 in a randomly selected representative population of 6,000 Polish adolescents aged 14-24 (of the total of adolescents, a population of females was selected for analysis), and the results of foetal period health monitoring of mother and child (PRAMS) which has been conducted in Poland since 2009 in the population of mothers and their newborn babies staying after delivery in all hospitals in Poland. Analysis of these two population studies indicates that a high percentage of Polish women at reproductive age are dieting. At the same time, confirmation of the fact of becoming pregnant occurs between weeks 5-8 after conception. This shows that until that time, the foetuses of women on the Apple weight loss diet develop conditions of nutritional deficits which, according to the DOHaD hypothesis, may result in epigenetic changes which increase the susceptibility of off spring in adulthood to civilization diseases: cardiovascular disorders, type 2 diabetes or metabolic syndrome. This hypothesis is confirmed by the high percentages of newborns in Poland born with low birth weight or prematurely born, as well as the fact that the percentage of anemia in pregnant Polish women is twice as high as in other developed countries. Simultaneously, a large number of babies are born with excessive birth weight (macrosomia). The author considers that in the countries of East-Central Europe the phenomenon observed is characteristic at present of the developing countries of the Third World, called the 'double burden of malnutrition'. This

  16. Assessing the origin of old apparent ages derived by Pb stepwise leaching of vein-hosted epidote from Mount Isa, northwest Queensland, Australia

    NASA Astrophysics Data System (ADS)

    Duncan, Robert J.; Maas, Roland

    2014-12-01

    Epidote metasomatism affected large areas of tholeiitic metabasalts of the ~1,780 Ma Eastern Creek Volcanics in the Western Fold Belt of the Proterozoic Mount Isa inlier. Hydrothermal epidote generally occurs in quartz veins parallel to or boudinaged within the dominant S2 fabrics which formed during the regional metamorphic peak at ~1,570 Ma associated with the Isan orogeny. Previously published stable isotopic and halogen data suggest that the fluids responsible for epidote formation are metamorphic in origin (with an evaporitic component). Application of the Pb stepwise leaching technique to the epidote does not separate radiogenic Pb4+ and common Pb2+, generating little spread in 206Pb/204Pb (between 16.0 and 30.5). The causes for this relatively low range are twofold: There is little radiogenic Pb in the epidotes (the most radiogenic steps account for <1 % of Pb released) and both Pb2+ and uranogenic Pb4+ substitute into the same site in the epidote crystal lattice. Consequently, age regressions using the Pb stepwise leaching data give ages between 150 and 1,500 myrs older than the host rocks and over 450 myrs older than the thermal metamorphic peak. These old ages are attributed to chemical inheritance from the host metabasalts, via radiogenic Pb release by breakdown of phases such as zircon, monazite, titanomagnetite, and ilmenite during metamorphism. This idea is supported by trace element data and chrondrite-normalized rare earth element patterns that are similar to both the metabasalts and epidotes (except for a variable Eu anomaly in the latter). Relatively high fO2 during vein formation (Fe3+ dominates in the epidote crystal lattice) would allow the incorporation of Th4+ and exclusion of U6+ and would explain elevated Th/U ratios (up to 12) in epidote compared with the host metabasalts. Non-incorporation of U would explain the relatively low U/Pb ratios and non-radiogenic character of the epidote. This process may provide a source of metal for the small

  17. A multi-tracer approach for assessing the origin, apparent age and recharge mechanism of shallow groundwater in the Lake Nyos catchment, Northwest, Cameroon

    NASA Astrophysics Data System (ADS)

    Kamtchueng, Brice Tchakam; Fantong, Wilson Yetoh; Wirmvem, Mengnjo Jude; Tiodjio, Rosine Edwige; Fouépé Takounjou, Alain; Asai, Kazuyoshi; Bopda Djomou, Serges L.; Kusakabe, Minoru; Ohba, Takeshi; Tanyileke, Gregory; Hell, Joseph Victor; Ueda, Akira

    2015-04-01

    The shallow aquifer in the vicinity of Lake Nyos (Northwest, Cameroon) is one of the main water supply sources to meet the water needs of the inhabitants to be resettled after 1986s tragedy. Unfortunately, there is a lack of knowledge on the groundwater recharge and flow systems in the area. Multiple environmental tracers (δ18O, δD, Cl-, CFCs and SF6) and a yearly record of rainfall, surface waters and groundwater were employed to characterize the recharge mechanism of the shallow groundwater seeping in the fractured rock of the Lake Nyos catchment (LNC). The δ18O-δD relationship of the rainfall events gave the Nyos Meteoric Water Line: δD = 8.28 δ18O + 11.87. Inland moisture vapor may have impacted the isotopic composition of original vapor masses from Gulf of Guinea prior to precipitation. Shallow groundwater in the LNC shows a similar trend of enrichment in 18O and D as surface waters indicating a well-mixed aquifer. The proportions of surface waters and rainfall in the groundwater reservoir were 87% and 13%, respectively. The high annual recharge rate (941 mm/yr) and the seasonal variability in the isotopic signatures of groundwater indicate a renewable aquifer system. CFCs apparent ages-based piston flow model revealed a young age (average of 24 a.) of the groundwater in the LNC. SF6-based ages were biased young as compared to relatively younger than CFCs-based ages, implying an additional terrigenic production of SF6. The conceptual model for groundwater flow suggests that three main flow regimes, mainly controlled by the physical properties of the rock heterogeneities govern the movement of water in the aquifer. The piston flow model appears, however, to be the better model to explain the flow regime in the highly faulted and fissured area where recharge occurs (∼1200-1600 masl). The rapid circulation and the low solubility lead to low mineralization. In the middle-lower area where waters circulate more in the weathered layer, exponential mixing

  18. Strategic priorities for increasing physical activity among adults age 50 and older: the national blueprint consensus conference summary report.

    PubMed

    Sheppard, Lisa; Senior, Jane; Park, Chae Hee; Mockenhaupt, Robin; Bazzarre, Terry; Chodzko-Zajko, Wojtek

    2003-12-01

    On May 1, 2001, a coalition of national organizations released a major planning document designed to develop a national strategy for the promotion of physically active lifestyles among the mid-life and older adult population. The National Blueprint: Increasing Physical Activity Among Adults Age 50 and Older was developed with input from 46 organizations with expertise in health, medicine, social and behavioral sciences, epidemiology, gerontology/geriatrics, clinical science, public policy, marketing, medical systems, community organization, and environmental issues. The Blueprint notes that, despite a wealth of evidence about the benefits of physical activity for mid-life and older persons, there has been little success in convincing age 50+ Americans to adopt physically active lifestyles. The Blueprint identifies barriers in the areas of research, home and community programs, medical systems, public policy and advocacy, and marketing and communications. In addition to identifying barriers, the Blueprint proposes a number of concrete strategies that could be employed in order to overcome the barriers to physical activity in society at large. This report summarizes the outcome of the National Blueprint Consensus Conference that was held in October 2002. In this conference, representatives of more than 50 national organizations convened in Washington, D.C. with the goal of identifying high priority and high feasibility strategies which would advance the National Blueprint and which could be initiated within the next 12 to 24 months. Participants in the consensus conference were assigned to one of five breakout groups: home and community, marketing, medical systems, public policy, and research. Each breakout group was charged with identifying the three highest priority strategies within their area for effectively increasing physical activity levels in the mid-life and older adult population. In addition to the 15 strategies identified by the breakout groups, three

  19. Pain in Community-Dwelling Older Adults with Dementia: Results from the National Health and Aging Trends Study

    PubMed Central

    Hunt, Lauren J.; Covinsky, Kenneth E.; Yaffe, Kristine; Stephens, Caroline E.; Miao, Yinghui; Boscardin, W. John; Smith, Alex K.

    2016-01-01

    OBJECTIVES To report prevalence, correlates, and medication management of pain in community-dwelling older adults with dementia. DESIGN Cross-sectional. SETTING In-person interviews with self- or proxy respondents living in private residences or non-nursing home residential care settings. PARTICIPANTS Nationally representative sample of community-dwelling Medicare beneficiaries aged 65 and older enrolled in the National Health and Aging Trends Study 2011 wave. MEASUREMENTS Dementia status was determined using a modified previously validated algorithm. Participants were asked whether they had had bothersome and activity-limiting pain over the past month. A multivariable Poisson regression model was used to determine the relationship between bothersome pain and sociodemographic and clinical characteristics. RESULTS Of the 7,609 participants with complete data on cognitive function, 802 had dementia (67.2% aged ≥80, 65.0% female, 67.9% white, 49.7% proxy response, 32.0% lived alone, 18.8% lived in residential care); 670 (63.5%) participants with dementia experienced bothersome pain, and 347 (43.3%) had pain that limited activities. These rates were significantly higher than in a propensity score–matched cohort without dementia (54.5% bothersome pain, P < .001, 27.2% pain that limited activity, P < .001). Proxies reported slightly higher rates of pain than self-respondents, but differences were statistically significant only for activity-limiting pain (46.6% proxy vs 40.1% self, P = .03). Correlates of bothersome pain included arthritis, heart and lung disease, less than high school education, activity of daily living disability, depressive and anxiety symptoms, and low energy. Of those reporting pain, 30.3% stated that they rarely or never took any medications for pain. CONCLUSION Community-living older adults with dementia are at high risk of having pain. Creative interventions and programs are needed to manage pain adequately in this vulnerable population. PMID

  20. Tetanus Immunity among Women Aged 15 to 39 Years in Cambodia: a National Population-Based Serosurvey, 2012.

    PubMed

    Scobie, Heather M; Mao, Bunsoth; Buth, Sokhal; Wannemuehler, Kathleen A; Sørensen, Charlotte; Kannarath, Chheng; Jenks, M Harley; Moss, Delynn M; Priest, Jeffrey W; Soeung, Sann Chan; Deming, Michael S; Lammie, Patrick J; Gregory, Christopher J

    2016-07-01

    To monitor progress toward maternal and neonatal tetanus elimination (MNTE) in Cambodia, we conducted a nationwide serosurvey of tetanus immunity in 2012. Multistage cluster sampling was used to select 2,154 women aged 15 to 39 years. Tetanus toxoid antibodies in serum samples were measured by gold-standard double-antigen enzyme-linked immunosorbent assay (DAE) and a novel multiplex bead assay (MBA). Antibody concentrations of ≥0.01 IU/ml by DAE or the equivalent for MBA were considered seroprotective. Estimated tetanus seroprotection was 88% (95% confidence interval [CI], 86 to 89%); 64% (95% CI, 61 to 67%) of women had antibody levels of ≥1.0 IU/ml. Seroprotection was significantly lower (P < 0.001) among women aged 15 to 19 years (63%) and 20 to 24 years (87%) than among those aged ≥25 years (96%), among nulliparous women than among parous women (71 versus 97%), and among those living in the western region than among those living in other regions (82 versus 89%). The MBA showed high sensitivity (99% [95% CI, 98 to 99%]) and specificity (92% [95% CI, 88 to 95%]) compared with DAE. Findings were compatible with MNTE in Cambodia (≥80% protection). Tetanus immunity gaps should be addressed through strengthened routine immunization and targeted vaccination campaigns. Incorporating tetanus testing in national serosurveys using MBAs, which can measure immunity to multiple pathogens simultaneously, may be beneficial for monitoring MNTE. PMID:27053629