Sample records for aged model samples
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A revised burial dose estimation procedure for optical dating of youngand modern-age sediments
Arnold, L.J.; Roberts, R.G.; Galbraith, R.F.; DeLong, S.B.
2009-01-01
The presence of genuinely zero-age or near-zero-age grains in modern-age and very young samples poses a problem for many existing burial dose estimation procedures used in optical (optically stimulated luminescence, OSL) dating. This difficulty currently necessitates consideration of relatively simplistic and statistically inferior age models. In this study, we investigate the potential for using modified versions of the statistical age models of Galbraith et??al. [Galbraith, R.F., Roberts, R.G., Laslett, G.M., Yoshida, H., Olley, J.M., 1999. Optical dating of single and multiple grains of quartz from Jinmium rock shelter, northern Australia: Part I, experimental design and statistical models. Archaeometry 41, 339-364.] to provide reliable equivalent dose (De) estimates for young and modern-age samples that display negative, zero or near-zero De estimates. For this purpose, we have revised the original versions of the central and minimum age models, which are based on log-transformed De values, so that they can be applied to un-logged De estimates and their associated absolute standard errors. The suitability of these 'un-logged' age models is tested using a series of known-age fluvial samples deposited within two arroyo systems from the American Southwest. The un-logged age models provide accurate burial doses and final OSL ages for roughly three-quarters of the total number of samples considered in this study. Sensitivity tests reveal that the un-logged versions of the central and minimum age models are capable of producing accurate burial dose estimates for modern-age and very young (<350??yr) fluvial samples that contain (i) more than 20% of well-bleached grains in their De distributions, or (ii) smaller sub-populations of well-bleached grains for which the De values are known with high precision. Our results indicate that the original (log-transformed) versions of the central and minimum age models are still preferable for most routine dating applications, since these age models are better suited to the statistical properties of typical single-grain and multi-grain single-aliquot De datasets. However, the unique error properties of modern-age samples, combined with the problems of calculating natural logarithms of negative or zero-Gy De values, mean that the un-logged versions of the central and minimum age models currently offer the most suitable means of deriving accurate burial dose estimates for very young and modern-age samples. ?? 2009 Elsevier Ltd. All rights reserved.
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NASA Astrophysics Data System (ADS)
Peyton, S. L.; Reiners, P. W.
2007-12-01
We dated borehole and surface samples from the Wind River and Beartooth Laramide-age, basement-cored uplifts of the Rocky Mountain foreland using the apatite (U-Th)/He (AHe) system. Comparison of these results to previously published apatite fission-track (AFT) data along with the incorporation of new He diffusion models (Shuster et al., 2006), reveals several new insights into, and poses new interpretational challenges for, the shallow exhumation histories of these ranges. Deep (2.2-2.8 km below surface) borehole samples from the Wind River Range have AHe ages of 9-12 Ma, and suggest at least 600 m of rapid exhumation during the Miocene. Shallower samples range from 35-66 Ma and are consistent with exhumation of a fossil partial retention zone. Previously-published apatite fission track (AFT) data from the same borehole show at least 2 km of rapid exhumation at ~45-38 Ma at depths where AHe ages are 9-50 Ma. This contrasts with the AHe ages which show slow exhumation between 12-66 Ma and have a trend on an age-elevation plot that appears to cut across the AFT age trend. Forward modeling of the cooling ages of these data using well-constrained thermal histories and conventional Durango apatite He diffusion data cannot explain these coupled AFT-AHe age-elevation relationships. However, modeling using diffusion kinetics of the Shuster et al. radiation-damage trapping model can explain the observed age trends, including the apparent presence of a 45-38 Ma exhumation event in the AFT data and its absence in the AHe data. In the model the shallow samples do not reach high enough temperatures for annealing of accumulated radiation damage, so He is trapped and ages are much older than predicted by conventional diffusion models. Previously-published AFT data from the Beartooth Range also show a large Laramide-age exhumation event, dated at 57-52 Ma. Similar to our observations from the Wind River Range, this event is not represented in our AHe results from borehole samples, which instead show slow cooling between at least 63-10 Ma. The trapping model predicts that the observed AHe age of a single apatite grain will be proportional to its effective Uranium content (eU), a proxy for radiation damage. Multiple single-grain replicates from a sample from the Wind River borehole are consistent with this, showing a strong correlation with eU. Although the trapping-diffusion model explains the coupled AFT-AHe data of borehole samples, surface samples from the Fremont Peak area in the Wind River Range have AHe ages that are older than the corresponding previously-published AFT ages over the 1.2 km elevation traverse sampled. AFT ages show ~1 km of rapid exhumation at ~62-58 Ma; corresponding AHe ages are as much as 20 Myr older. Although the radiation damage trapping model predicts that some AHe ages may be older than the corresponding AFT ages, thermal- diffusion forward models cannot explain these large age differences over such a large sampling interval, even if trapping model kinetic parameters are varied by 5%. Thus, discrepancies in AFT and AHe ages of these surficial samples remain problematic. The thermal histories required to approximate the borehole data require burial up to the end of the Cretaceous of ~3-4 km followed by at least two phases of cooling and exhumation. The first and larger cooling event of several tens of degrees (~3-4 km of exhumation) occurred during the Paleocene-Eocene, followed by a smaller cooling event of a few tens of degrees (~1 km of exhumation) during the Miocene.
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Godde, Kanya
2017-01-01
The aim of this study is to examine how well different informative priors model age-at-death in Bayesian statistics, which will shed light on how the skeleton ages, particularly at the sacroiliac joint. Data from four samples were compared for their performance as informative priors for auricular surface age-at-death estimation: (1) American population from US Census data; (2) county data from the US Census data; (3) a local cemetery; and (4) a skeletal collection. The skeletal collection and cemetery are located within the county that was sampled. A Gompertz model was applied to compare survivorship across the four samples. Transition analysis parameters, coupled with the generated Gompertz parameters, were input into Bayes' theorem to generate highest posterior density ranges from posterior density functions. Transition analysis describes the age at which an individual transitions from one age phase to another. The result is age ranges that should describe the chronological age of 90% of the individuals who fall in a particular phase. Cumulative binomial tests indicate the method performed lower than 90% at capturing chronological age as assigned to a biological phase, despite wide age ranges at older ages. The samples performed similarly overall, despite small differences in survivorship. Collectively, these results show that as we age, the senescence pattern becomes more variable. More local samples performed better at describing the aging process than more general samples, which implies practitioners need to consider sample selection when using the literature to diagnose and work with patients with sacroiliac joint pain.
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Dental age estimation in Japanese individuals combining permanent teeth and third molars.
Ramanan, Namratha; Thevissen, Patrick; Fleuws, Steffen; Willems, G
2012-12-01
The study aim was, firstly, to verify the Willems et al. model on a Japanese reference sample. Secondly to develop a Japanese reference model based on the Willems et al. method and to verify it. Thirdly to analyze the age prediction performance adding tooth development information of third molars to permanent teeth. Retrospectively 1877 panoramic radiographs were selected in the age range between 1 and 23 years (1248 children, 629 sub-adults). Dental development was registered applying Demirjian 's stages of the mandibular left permanent teeth in children and Köhler stages on the third molars. The children's data were, firstly, used to validate the Willems et al. model (developed a Belgian reference sample), secondly, split ino a training and a test sample. On the training sample a Japanese reference model was developed based on the Willems method. The developed model and the Willems et al; model were verified on the test sample. Regression analysis was used to detect the age prediction performance adding third molar scores to permanent tooth scores. The validated Willems et al. model provided a mean absolute error of 0.85 and 0.75 years in females and males, respectively. The mean absolute error in the verified Willems et al. and the developed Japanese reference model was 0.85, 0.77 and 0.79, 0.75 years in females and males, respectively. On average a negligible change in root mean square error values was detected adding third molar scores to permanent teeth scores. The Belgian sample could be used as a reference model to estimate the age of the Japanese individuals. Combining information from the third molars and permanent teeth was not providing clinically significant improvement of age predictions based on permanent teeth information alone.
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Godde, Kanya
2017-01-01
The aim of this study is to examine how well different informative priors model age-at-death in Bayesian statistics, which will shed light on how the skeleton ages, particularly at the sacroiliac joint. Data from four samples were compared for their performance as informative priors for auricular surface age-at-death estimation: (1) American population from US Census data; (2) county data from the US Census data; (3) a local cemetery; and (4) a skeletal collection. The skeletal collection and cemetery are located within the county that was sampled. A Gompertz model was applied to compare survivorship across the four samples. Transition analysis parameters, coupled with the generated Gompertz parameters, were input into Bayes' theorem to generate highest posterior density ranges from posterior density functions. Transition analysis describes the age at which an individual transitions from one age phase to another. The result is age ranges that should describe the chronological age of 90% of the individuals who fall in a particular phase. Cumulative binomial tests indicate the method performed lower than 90% at capturing chronological age as assigned to a biological phase, despite wide age ranges at older ages. The samples performed similarly overall, despite small differences in survivorship. Collectively, these results show that as we age, the senescence pattern becomes more variable. More local samples performed better at describing the aging process than more general samples, which implies practitioners need to consider sample selection when using the literature to diagnose and work with patients with sacroiliac joint pain. PMID:29546217
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Corron, Louise; Marchal, François; Condemi, Silvana; Chaumoître, Kathia; Adalian, Pascal
2017-01-01
Juvenile age estimation methods used in forensic anthropology generally lack methodological consistency and/or statistical validity. Considering this, a standard approach using nonparametric Multivariate Adaptive Regression Splines (MARS) models were tested to predict age from iliac biometric variables of male and female juveniles from Marseilles, France, aged 0-12 years. Models using unidimensional (length and width) and bidimensional iliac data (module and surface) were constructed on a training sample of 176 individuals and validated on an independent test sample of 68 individuals. Results show that MARS prediction models using iliac width, module and area give overall better and statistically valid age estimates. These models integrate punctual nonlinearities of the relationship between age and osteometric variables. By constructing valid prediction intervals whose size increases with age, MARS models take into account the normal increase of individual variability. MARS models can qualify as a practical and standardized approach for juvenile age estimation. © 2016 American Academy of Forensic Sciences.
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Jurgens, Bryant C.; Böhlke, J.K.; Eberts, Sandra M.
2012-01-01
TracerLPM is an interactive Excel® (2007 or later) workbook program for evaluating groundwater age distributions from environmental tracer data by using lumped parameter models (LPMs). Lumped parameter models are mathematical models of transport based on simplified aquifer geometry and flow configurations that account for effects of hydrodynamic dispersion or mixing within the aquifer, well bore, or discharge area. Five primary LPMs are included in the workbook: piston-flow model (PFM), exponential mixing model (EMM), exponential piston-flow model (EPM), partial exponential model (PEM), and dispersion model (DM). Binary mixing models (BMM) can be created by combining primary LPMs in various combinations. Travel time through the unsaturated zone can be included as an additional parameter. TracerLPM also allows users to enter age distributions determined from other methods, such as particle tracking results from numerical groundwater-flow models or from other LPMs not included in this program. Tracers of both young groundwater (anthropogenic atmospheric gases and isotopic substances indicating post-1940s recharge) and much older groundwater (carbon-14 and helium-4) can be interpreted simultaneously so that estimates of the groundwater age distribution for samples with a wide range of ages can be constrained. TracerLPM is organized to permit a comprehensive interpretive approach consisting of hydrogeologic conceptualization, visual examination of data and models, and best-fit parameter estimation. Groundwater age distributions can be evaluated by comparing measured and modeled tracer concentrations in two ways: (1) multiple tracers analyzed simultaneously can be evaluated against each other for concordance with modeled concentrations (tracer-tracer application) or (2) tracer time-series data can be evaluated for concordance with modeled trends (tracer-time application). Groundwater-age estimates can also be obtained for samples with a single tracer measurement at one point in time; however, prior knowledge of an appropriate LPM is required because the mean age is often non-unique. LPM output concentrations depend on model parameters and sample date. All of the LPMs have a parameter for mean age. The EPM, PEM, and DM have an additional parameter that characterizes the degree of age mixing in the sample. BMMs have a parameter for the fraction of the first component in the mixture. An LPM, together with its parameter values, provides a description of the age distribution or the fractional contribution of water for every age of recharge contained within a sample. For the PFM, the age distribution is a unit pulse at one distinct age. For the other LPMs, the age distribution can be much broader and span decades, centuries, millennia, or more. For a sample with a mixture of groundwater ages, the reported interpretation of tracer data includes the LPM name, the mean age, and the values of any other independent model parameters. TracerLPM also can be used for simulating the responses of wells, springs, streams, or other groundwater discharge receptors to nonpoint-source contaminants that are introduced in recharge, such as nitrate. This is done by combining an LPM or user-defined age distribution with information on contaminant loading at the water table. Information on historic contaminant loading can be used to help evaluate a model's ability to match real world conditions and understand observed contaminant trends, while information on future contaminant loading scenarios can be used to forecast potential contaminant trends.
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Sheets, Rodney A.; Bair, E. Scott; Rowe, Gary L.
1998-01-01
Combined use of the tritium/helium 3 (3H/3He) dating technique and particle-tracking analysis can improve flow-model calibration. As shown at two sites in the Great Miami buried-valley aquifer in southwestern Ohio, the combined use of 3H/3He age dating and particle tracking led to a lower mean absolute error between measured heads and simulated heads than in the original calibrated models and/or between simulated travel times and 3H/3He ages. Apparent groundwater ages were obtained for water samples collected from 44 wells at two locations where previously constructed finite difference models of groundwater flow were available (Mound Plant and Wright-Patterson Air Force Base (WPAFB)). The two-layer Mound Plant model covers 11 km2 within the buried-valley aquifer. The WPAFB model has three layers and covers 262 km2 within the buried-valley aquifer and adjacent bedrock uplands. Sampled wells were chosen along flow paths determined from potentiometric maps or particle-tracking analyses. Water samples were collected at various depths within the aquifer. In the Mound Plant area, samples used for comparison of 3H/3He ages with simulated travel times were from wells completed in the uppermost model layer. Simulated travel times agreed well with 3H/3He ages. The mean absolute error (MAE) was 3.5 years. Agreement in ages at WPAFB decreased with increasing depth in the system. The MAEs were 1.63, 17.2, and 255 years for model layers 1, 2, and 3, respectively. Discrepancies between the simulated travel times and 3H/3He ages were assumed to be due to improper conceptualization or incorrect parameterization of the flow models. Selected conceptual and parameter modifications to the models resulted in improved agreement between 3H/3He ages and simulated travel times and between measured and simulated heads and flows.
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Chang, Xiangwei; Zhang, Juanjuan; Li, Dekun; Zhou, Dazheng; Zhang, Yuling; Wang, Jincheng; Hu, Bing; Ju, Aichun; Ye, Zhengliang
2017-07-15
The adulteration or falsification of the cultivation age of mountain cultivated ginseng (MCG) has been a serious problem in the commercial MCG market. To develop an efficient discrimination tool for the cultivation age and to explore potential age-dependent markers, an optimized ultra high-performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UHPLC/QTOF-MS)-based metabolomics approach was applied in the global metabolite profiling of 156 MCG leaf (MGL) samples aged from 6 to 18 years. Multivariate statistical methods such as principal component analysis (PCA) and partial least squares discriminant analysis (PLS-DA) were used to compare the derived patterns between MGL samples of different cultivation ages. The present study demonstrated that 6-18-year-old MGL samples can be successfully discriminated using two simple successive steps, together with four PLS-DA discrimination models. Furthermore, 39 robust age-dependent markers enabling differentiation among the 6-18-year-old MGL samples were discovered. The results were validated by a permutation test and an external test set to verify the predictability and reliability of the established discrimination models. More importantly, without destroying the MCG roots, the proposed approach could also be applied to discriminate MCG root ages indirectly, using a minimum amount of homophyletic MGL samples combined with the established four PLS-DA models and identified markers. Additionally, to the best of our knowledge, this is the first study in which 6-18-year-old MCG root ages have been nondestructively differentiated by analyzing homophyletic MGL samples using UHPLC/QTOF-MS analysis and two simple successive steps together with four PLS-DA models. The method developed in this study can be used as a standard protocol for discriminating and predicting MGL ages directly and homophyletic MCG root ages indirectly. Copyright © 2017 Elsevier B.V. All rights reserved.
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Alghanim, Hussain; Antunes, Joana; Silva, Deborah Soares Bispo Santos; Alho, Clarice Sampaio; Balamurugan, Kuppareddi; McCord, Bruce
2017-11-01
Recent developments in the analysis of epigenetic DNA methylation patterns have demonstrated that certain genetic loci show a linear correlation with chronological age. It is the goal of this study to identify a new set of epigenetic methylation markers for the forensic estimation of human age. A total number of 27 CpG sites at three genetic loci, SCGN, DLX5 and KLF14, were examined to evaluate the correlation of their methylation status with age. These sites were evaluated using 72 blood samples and 91 saliva samples collected from volunteers with ages ranging from 5 to 73 years. DNA was bisulfite modified followed by PCR amplification and pyrosequencing to determine the level of DNA methylation at each CpG site. In this study, certain CpG sites in SCGN and KLF14 loci showed methylation levels that were correlated with chronological age, however, the tested CpG sites in DLX5 did not show a correlation with age. Using a 52-saliva sample training set, two age-predictor models were developed by means of a multivariate linear regression analysis for age prediction. The two models performed similarly with a single-locus model explaining 85% of the age variance at a mean absolute deviation of 5.8 years and a dual-locus model explaining 84% of the age variance with a mean absolute deviation of 6.2 years. In the validation set, the mean absolute deviation was measured to be 8.0 years and 7.1 years for the single- and dual-locus model, respectively. Another age predictor model was also developed using a 40-blood sample training set that accounted for 71% of the age variance. This model gave a mean absolute deviation of 6.6 years for the training set and 10.3years for the validation set. The results indicate that specific CpGs in SCGN and KLF14 can be used as potential epigenetic markers to estimate age using saliva and blood specimens. These epigenetic markers could provide important information in cases where the determination of a suspect's age is critical in developing investigative leads. Copyright © 2017. Published by Elsevier B.V.
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Night sampling improves indices used for management of yellow perch in Lake Erie
Kocovsky, P.M.; Stapanian, M.A.; Knight, C.T.
2010-01-01
Catch rate (catch per hour) was examined for age-0 and age-1 yellow perch, Perca flavescens (Mitchill), captured in bottom trawls from 1991 to 2005 in western Lake Erie: (1) to examine variation of catch rate among years, seasons, diel periods and their interactions; and (2) to determine whether sampling during particular diel periods improved the management value of CPH data used in models to project abundance of age-2 yellow perch. Catch rate varied with year, season and the diel period during which sampling was conducted as well as by the interaction between year and season. Indices of abundance of age-0 and age-1 yellow perch estimated from night samples typically produced better fitting models and lower estimates of age-2 abundance than those using morning or afternoon samples, whereas indices using afternoon samples typically produced less precise and higher estimates of abundance. The diel period during which sampling is conducted will not affect observed population trends but may affect estimates of abundance of age-0 and age-1 yellow perch, which in turn affect recommended allowable harvest. A field experiment throughout western Lake Erie is recommended to examine potential benefits of night sampling to management of yellow perch. Published 2010. The article is a US Government work and is in the public domain in the USA.
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2D Models for the evolving distribution of impact melt at the lunar near-surface
NASA Astrophysics Data System (ADS)
Liu, T.; Michael, G. G.; Oberst, J.
2017-09-01
This study aims to investigate the cumulative effect of the impact gardening process. The lateral distribution of the melt with diverse ages is traced in this model. Using the observed distribution of melt age in lunar samples and meteorites, the possible scenarios of the lunar impact history can be discriminated. The record is also helpful for the future lunar sampling, guiding the choice of site to obtain samples from different impact basins, and to understand the mixture of melt ages observed at any one site.
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Han, L. F; Plummer, Niel
2016-01-01
Numerous methods have been proposed to estimate the pre-nuclear-detonation 14C content of dissolved inorganic carbon (DIC) recharged to groundwater that has been corrected/adjusted for geochemical processes in the absence of radioactive decay (14C0) - a quantity that is essential for estimation of radiocarbon age of DIC in groundwater. The models/approaches most commonly used are grouped as follows: (1) single-sample-based models, (2) a statistical approach based on the observed (curved) relationship between 14C and δ13C data for the aquifer, and (3) the geochemical mass-balance approach that constructs adjustment models accounting for all the geochemical reactions known to occur along a groundwater flow path. This review discusses first the geochemical processes behind each of the single-sample-based models, followed by discussions of the statistical approach and the geochemical mass-balance approach. Finally, the applications, advantages and limitations of the three groups of models/approaches are discussed.The single-sample-based models constitute the prevailing use of 14C data in hydrogeology and hydrological studies. This is in part because the models are applied to an individual water sample to estimate the 14C age, therefore the measurement data are easily available. These models have been shown to provide realistic radiocarbon ages in many studies. However, they usually are limited to simple carbonate aquifers and selection of model may have significant effects on 14C0 often resulting in a wide range of estimates of 14C ages.Of the single-sample-based models, four are recommended for the estimation of 14C0 of DIC in groundwater: Pearson's model, (Ingerson and Pearson, 1964; Pearson and White, 1967), Han & Plummer's model (Han and Plummer, 2013), the IAEA model (Gonfiantini, 1972; Salem et al., 1980), and Oeschger's model (Geyh, 2000). These four models include all processes considered in single-sample-based models, and can be used in different ranges of 13C values.In contrast to the single-sample-based models, the extended Gonfiantini & Zuppi model (Gonfiantini and Zuppi, 2003; Han et al., 2014) is a statistical approach. This approach can be used to estimate 14C ages when a curved relationship between the 14C and 13C values of the DIC data is observed. In addition to estimation of groundwater ages, the relationship between 14C and δ13C data can be used to interpret hydrogeological characteristics of the aquifer, e.g. estimating apparent rates of geochemical reactions and revealing the complexity of the geochemical environment, and identify samples that are not affected by the same set of reactions/processes as the rest of the dataset. The investigated water samples may have a wide range of ages, and for waters with very low values of 14C, the model based on statistics may give more reliable age estimates than those obtained from single-sample-based models. In the extended Gonfiantini & Zuppi model, a representative system-wide value of the initial 14C content is derived from the 14C and δ13C data of DIC and can differ from that used in single-sample-based models. Therefore, the extended Gonfiantini & Zuppi model usually avoids the effect of modern water components which might retain ‘bomb’ pulse signatures.The geochemical mass-balance approach constructs an adjustment model that accounts for all the geochemical reactions known to occur along an aquifer flow path (Plummer et al., 1983; Wigley et al., 1978; Plummer et al., 1994; Plummer and Glynn, 2013), and includes, in addition to DIC, dissolved organic carbon (DOC) and methane (CH4). If sufficient chemical, mineralogical and isotopic data are available, the geochemical mass-balance method can yield the most accurate estimates of the adjusted radiocarbon age. The main limitation of this approach is that complete information is necessary on chemical, mineralogical and isotopic data and these data are often limited.Failure to recognize the limitations and underlying assumptions on which the various models and approaches are based can result in a wide range of estimates of 14C0 and limit the usefulness of radiocarbon as a dating tool for groundwater. In each of the three generalized approaches (single-sample-based models, statistical approach, and geochemical mass-balance approach), successful application depends on scrutiny of the isotopic (14C and 13C) and chemical data to conceptualize the reactions and processes that affect the 14C content of DIC in aquifers. The recently developed graphical analysis method is shown to aid in determining which approach is most appropriate for the isotopic and chemical data from a groundwater system.
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Aging and Confidence Judgments in Item Recognition
ERIC Educational Resources Information Center
Voskuilen, Chelsea; Ratcliff, Roger; McKoon, Gail
2018-01-01
We examined the effects of aging on performance in an item-recognition experiment with confidence judgments. A model for confidence judgments and response time (RTs; Ratcliff & Starns, 2013) was used to fit a large amount of data from a new sample of older adults and a previously reported sample of younger adults. This model of confidence…
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Corron, Louise; Marchal, François; Condemi, Silvana; Telmon, Norbert; Chaumoitre, Kathia; Adalian, Pascal
2018-05-31
Subadult age estimation should rely on sampling and statistical protocols capturing development variability for more accurate age estimates. In this perspective, measurements were taken on the fifth lumbar vertebrae and/or clavicles of 534 French males and females aged 0-19 years and the ilia of 244 males and females aged 0-12 years. These variables were fitted in nonparametric multivariate adaptive regression splines (MARS) models with 95% prediction intervals (PIs) of age. The models were tested on two independent samples from Marseille and the Luis Lopes reference collection from Lisbon. Models using ilium width and module, maximum clavicle length, and lateral vertebral body heights were more than 92% accurate. Precision was lower for postpubertal individuals. Integrating punctual nonlinearities of the relationship between age and the variables and dynamic prediction intervals incorporated the normal increase in interindividual growth variability (heteroscedasticity of variance) with age for more biologically accurate predictions. © 2018 American Academy of Forensic Sciences.
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De Luca, Stefano; Mangiulli, Tatiana; Merelli, Vera; Conforti, Federica; Velandia Palacio, Luz Andrea; Agostini, Susanna; Spinas, Enrico; Cameriere, Roberto
2016-04-01
The aim of this study is to develop a specific formula for the purpose of assessing skeletal age in a sample of Italian growing infants and children by measuring carpals and epiphyses of radio and ulna. A sample of 332 X-rays of left hand-wrist bones (130 boys and 202 girls), aged between 1 and 16 years, was analyzed retrospectively. Analysis of covariance (ANCOVA) was applied to study how sex affects the growth of the ratio Bo/Ca in the boys and girls groups. The regression model, describing age as a linear function of sex and the Bo/Ca ratio for the new Italian sample, yielded the following formula: Age = -1.7702 + 1.0088 g + 14.8166 (Bo/Ca). This model explained 83.5% of total variance (R(2) = 0.835). The median of the absolute values of residuals (observed age minus predicted age) was -0.38, with a quartile deviation of 2.01 and a standard error of estimate of 1.54. A second sample test of 204 Italian children (108 girls and 96 boys), aged between 1 and 16 years, was used to evaluate the accuracy of the specific regression model. A sample paired t-test was used to analyze the mean differences between the skeletal and chronological age. The mean error for girls is 0.00 and the estimated age is slightly underestimated in boys with a mean error of -0.30 years. The standard deviations are 0.70 years for girls and 0.78 years for boys. The obtained results indicate that there is a high relationship between estimated and chronological ages. Copyright © 2016 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.
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Jatautis, Šarūnas; Jankauskas, Rimantas
2018-02-01
Objectives. The present study addresses the following two main questions: a) Is the pattern of skeletal ageing observed in well-known western European reference collections applicable to modern eastern Baltic populations, or are population-specific standards needed? b) What are the consequences for estimating the age-at-death distribution in the target population when differences in the estimates from reference data are not taken into account? Materials and methods. The dataset consists of a modern Lithuanian osteological reference collection, which is the only collection of this type in the eastern Baltic countries (n = 381); and two major western European reference collections, Coimbra (n = 264) and Spitalfields (n = 239). The age-related changes were evaluated using the scoring systems of Suchey-Brooks (Brooks & Suchey 1990) and Lovejoy et al. (1985), and were modelled via regression models for multinomial responses. A controlled experiment based on simulations and the Rostock Manifesto estimation protocol (Wood et al. 2002) was then carried out to assess the effect of using estimates from different reference samples and different regression models on estimates of the age-at-death distribution in the hypothetical target population. Results. The following key results were obtained in this study. a) The morphological alterations in the pubic symphysis were much faster among women than among men at comparable ages in all three reference samples. In contrast, we found no strong evidence in any of the reference samples that sex is an important factor to explain rate of changes in the auricular surface. b) The rate of ageing in the pubic symphysis seems to be similar across the three reference samples, but there is little evidence of a similar pattern in the auricular surface. That is, the estimated rate of age-related changes in the auricular surface was much faster in the LORC and the Coimbra samples than in the Spitalfields sample. c) The results of simulations showed that the differences in the estimates from the reference data result in noticeably different age-at-death distributions in the target population. Thus, a degree bias may be expected if estimates from the western European reference data are used to collect information on ages at death in the eastern Baltic region based on the changes in the auricular surface. d) Moreover, the bias is expected to be more pronounced if the fitted regression model improperly describes the reference data. Conclusions. Differences in the timing of age-related changes in skeletal traits are to be expected among European reference samples, and cannot be ignored when seeking to reliably estimate an age-at-death distribution in the target population. This form of bias should be taken into consideration in further studies of skeletal samples from the eastern Baltic region.
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Age at onset in bipolar I affective disorder in the USA and Europe.
Bellivier, Frank; Etain, Bruno; Malafosse, Alain; Henry, Chantal; Kahn, Jean-Pierre; Elgrabli-Wajsbrot, Orly; Jamain, Stéphane; Azorin, Jean-Michel; Frank, Ellen; Scott, Jan; Grochocinski, Victoria; Kupfer, David J; Golmard, Jean-Louis; Leboyer, Marion
2014-07-01
To test for differences in reported age at onset (AAO) of bipolar I affective disorder in clinical samples drawn from Europe and the USA. Admixture analysis was used to identify the model best fitting the observed AAO distributions of two large samples of bipolar I patients from Europe and USA (n = 3616 and n = 2275, respectively). Theoretical AAO functions were compared between the two samples. The model best fitting the observed distribution of AAO in both samples was a mixture of three Gaussian distributions. The theoretical AAO functions of bipolar I disorder differed significantly between the European and USA populations, with further analyses indicating that (i) the proportion of patients belonging to the early-onset subgroup was higher in the USA sample (63 vs. 25%) and (ii) mean age at onset (±SD) in the early-onset subgroup was lower for the USA sample (14.5 ± 4.9 vs. 19 ± 2.7 years). The models best describing the reported AAO distributions of European and USA bipolar I patients were remarkably stable. The intermediate- and late-onset subgroups had similar characteristics in the two samples. However, the theoretical AAO function differed significantly between the USA and European samples due to the higher proportion of patients in the early-onset subgroup and the lower mean age-at-onset in the USA sample.
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Kamalandua, Aubeline
2015-01-01
Age estimation from DNA methylation markers has seen an exponential growth of interest, not in the least from forensic scientists. The current published assays, however, can still be improved by lowering the number of markers in the assay and by providing more accurate models to predict chronological age. From the published literature we selected 4 age-associated genes (ASPA, PDE4C, ELOVL2, and EDARADD) and determined CpG methylation levels from 206 blood samples of both deceased and living individuals (age range: 0–91 years). This data was subsequently used to compare prediction accuracy with both linear and non-linear regression models. A quadratic regression model in which the methylation levels of ELOVL2 were squared showed the highest accuracy with a Mean Absolute Deviation (MAD) between chronological age and predicted age of 3.75 years and an adjusted R2 of 0.95. No difference in accuracy was observed for samples obtained either from living and deceased individuals or between the 2 genders. In addition, 29 teeth from different individuals (age range: 19–70 years) were analyzed using the same set of markers resulting in a MAD of 4.86 years and an adjusted R2 of 0.74. Cross validation of the results obtained from blood samples demonstrated the robustness and reproducibility of the assay. In conclusion, the set of 4 CpG DNA methylation markers is capable of producing highly accurate age predictions for blood samples from deceased and living individuals PMID:26280308
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NASA Astrophysics Data System (ADS)
Goble, D.; Gardner, W. P.; Naftz, D. L.; Solder, J. E.
2017-12-01
We use environmental tracers: CFC's, SF6, and 222Rn measured in stream water to determine volume and mean age of groundwater discharging to the Little Wind River, near Riverton, Wyoming. Samples of 222Rn were collected every 200 m along a 2 km reach, surrounding a known groundwater discharge zone. Nearby groundwater wells, in-stream piezometers and seepage meters were sampled for 222Rn, CFC's and SF6. Tracer concentrations measured in groundwater and in-stream piezometers were used to estimate the mean age of the subsurface system. High resolution 222Rn samples were used to determine the location and volume of groundwater inflow using a model of instream transport that includes radioactive decay and gas exchange with the atmosphere. The age of groundwater entering the stream was then estimated from in-stream measured CFC and SF6 concentrations using a new coupled stream transport and lumped-parameter groundwater age model. Ages derived from in-stream measurements were then compared to the age of subsurface water measured in piezometers, seepage meters, and groundwater wells. We then asses the ability of groundwater age inferred from in-stream samples to provide constraint on the age of the subsurface discharge to the stream. The ability to asses groundwater age from in-stream samples can provide a convenient method to constrain the regional distribution of groundwater circulation rates when groundwater sampling is challenging or wells are not in place.
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230Th-234U Model-Ages of Some Uranium Standard Reference Materials
DOE Office of Scientific and Technical Information (OSTI.GOV)
Williams, R W; Gaffney, A M; Kristo, M J
The 'age' of a sample of uranium is an important aspect of a nuclear forensic investigation and of the attribution of the material to its source. To the extent that the sample obeys the standard rules of radiochronometry, then the production ages of even very recent material can be determined using the {sup 230}Th-{sup 234}U chronometer. These standard rules may be summarized as (a) the daughter/parent ratio at time=zero must be known, and (b) there has been no daughter/parent fractionation since production. For most samples of uranium, the 'ages' determined using this chronometer are semantically 'model-ages' because (a) some assumptionmore » of the initial {sup 230}Th content in the sample is required and (b) closed-system behavior is assumed. The uranium standard reference materials originally prepared and distributed by the former US National Bureau of Standards and now distributed by New Brunswick Laboratory as certified reference materials (NBS SRM = NBL CRM) are good candidates for samples where both rules are met. The U isotopic standards have known purification and production dates, and closed-system behavior in the solid form (U{sub 3}O{sub 8}) may be assumed with confidence. We present here {sup 230}Th-{sup 234}U model-ages for several of these standards, determined by isotope dilution mass spectrometry using a multicollector ICP-MS, and compare these ages with their known production history.« less
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Successful aging in Spanish older adults: the role of psychosocial resources.
Dumitrache, Cristina G; Rubio, Laura; Cordón-Pozo, Eulogio
2018-05-25
ABSTRACTBackground:Psychological and social resources such as extraversion, optimism, social support, or social networks contribute to adaptation and to successful aging. Building on assumptions derived from successful aging and from the developmental adaptation models, this study aims to analyze the joint impact of different psychosocial resources, such as personality, social relations, health, and socio-demographic characteristics on life satisfaction in a group of people aged 65 years-old and older from Spain. A cross-sectional survey using non-proportional quota sampling was carried out. The sample comprised 406 community-dwelling older adults (M = 74.88, SD = 6.75). In order to collect the data, face-to-face interviews were individually conducted. A structural equation model (SEM) was carried out using the PLS software. The results of the SEM model showed that, within this sample, psychosocial variables explain 47.4% of the variance in life satisfaction. Social relations and personality, specifically optimism, were strongly related with life satisfaction, while health status and socio-demographic characteristics were modestly associated with life satisfaction. Findings support the view that psychosocial resources are important for successful aging and therefore should be included in successful aging models. Furthermore, interventions aimed at fostering successful aging should take into account the role of psychosocial variables.
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Expanding Spatial Coverage of Geomagnetic Field Models Using Submarine Basaltic Glass
NASA Astrophysics Data System (ADS)
Schoeller, L. M.; Bowles, J. A.; Dreyer, B.; Clague, D. A.
2009-12-01
In recent years, paleointensity of submarine basaltic glass (SBG) has been used to constrain the ages of young mid-ocean ridge flows, often in the absence of more precise age data. In the present study, samples taken from the Co-Axial segment of the Juan de Fuca Ridge allow for further testing of the paleointensity dating technique; they also provide an assessment of the feasibility of incorporating SBG data into geomagnetic field models when independent age constraints are available. The nine sampled sites include six for which 14C dating of overlying sediments provides minimum ages (950 - 6400 ybp) for the flows, and three sites from historical flows. Absolute paleointensity estimates were derived using a Thellier-type method. The paleointensities of the samples ranged from 51.8 µT to 71.1 µT (VADM 8.3 to 11.6 x 1022 Am2). We compare results from the young (historical) flows directly with the International Geomagnetic Reference Field (IGRF), and two out of three sites are consistent with IGRF. The third gives paleointensity values that are considerably higher than would be expected based on IGRF. The rest of the samples can be compared with geomagnetic field models based on archeomagnetic and paleomagnetic data. Paleointensity values from samples < 3ka are consistent with the CALS3K.3 model (Korte et al., Geochem. Geophys. Geosys., 10, Q06008, doi:10.1029/2008GC002297, 2009), given the approximate ages provided by the 14C dating of the overlying sediments. Data constraining current geomagnetic field models are spatially quite limited, with the vast majority restricted to northern hemispheric continental regions. We suggest that data from mid-ocean ridges are suitable for incorporation into such models, with the potential to greatly expand spatial coverage.
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Romero-Pastor, Julia; Navas, Natalia; Kuckova, Stepanka; Rodríguez-Navarro, Alejandro; Cardell, Carolina
2012-03-01
This study focuses on acquiring information on the degradation process of proteinaceous binders due to ultra violet (UV) radiation and possible interactions owing to the presence of historical mineral pigments. With this aim, three different paint model samples were prepared according to medieval recipes, using rabbit glue as proteinaceus binders. One of these model samples contained only the binder, and the other two were prepared by mixing each of the pigments (cinnabar or azurite) with the binder (glue tempera model samples). The model samples were studied by applying Principal Component Analysis (PCA) to their mass spectra obtained with Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry (MALDI-TOF-MS). The complementary use of Fourier Transform Infrared Spectroscopy to study conformational changes of secondary structure of the proteinaceous binder is also proposed. Ageing effects on the model samples after up to 3000 h of UV irradiation were periodically analyzed by the proposed approach. PCA on MS data proved capable of identifying significant changes in the model samples, and the results suggested different aging behavior based on the pigment present. This research represents the first attempt to use this approach (PCA on MALDI-TOF-MS data) in the field of Cultural Heritage and demonstrates the potential benefits in the study of proteinaceous artistic materials for purposes of conservation and restoration. Copyright © 2012 John Wiley & Sons, Ltd.
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Apparent CFC and 3H/ 3He age differences in water from Floridan Aquifer springs
NASA Astrophysics Data System (ADS)
Happell, James D.; Opsahl, Stephen; Top, Zafer; Chanton, Jeffrey P.
2006-03-01
The apparent CFC-11, -12 and -113 ages of Upper Floridan Aquifer water discharged from 31 springs located in Florida and Georgia ranged from 11 to 44 years when samples were collected in 2002 and 2003. Apparent 3H/ 3He ages in these springs ranged from 12 to 66 years. Some of the springs sampled did not yield valid CFC ages because one or more of the CFCs were contaminated by non-atmospheric sources. Of the 31 springs sampled, six were contaminated with all three CFCs and nine were contaminated with one or two CFCs. Of the remaining 16 springs, the CFC distributions of four could be modeled assuming a single source of water, and 11 were best modeled by assuming two sources of water, with one of the water sources >60 years old. The CFC and 3H/ 3He apparent ages and the simple mixing models applied to these ages suggest that past impacts to the water quality of water recharging the sampled springs may take anywhere from 0 to ˜60 years or more to appear in the discharging spring water. In 27 springs where both 3H/ 3He ages and CFC ages were available, five springs gave similar results between the two techniques, while in the other 22 cases the 3H/ 3He apparent ages were 8-40 years greater than the CFC ages. Large excesses of 4He were observed in many of the springs, consistent with a source of older water. This older water may also carry an additional and unaccounted for source of 3He, which may be responsible for the greater 3H/ 3He ages relative to the CFC ages. We believe that the large excess 3He and 4He values and apparent age differences are related to regional climate variations because our samples were obtained at the end of a 4-year drought.
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Population Pharmacokinetics of Metronidazole Evaluated Using Scavenged Samples from Preterm Infants
Ouellet, Daniele; Smith, P. Brian; James, Laura P.; Ross, Ashley; Sullivan, Janice E.; Walsh, Michele C.; Zadell, Arlene; Newman, Nancy; White, Nicole R.; Kashuba, Angela D. M.; Benjamin, Daniel K.
2012-01-01
Pharmacokinetic (PK) studies in preterm infants are rarely conducted due to the research challenges posed by this population. To overcome these challenges, minimal-risk methods such as scavenged sampling can be used to evaluate the PK of commonly used drugs in this population. We evaluated the population PK of metronidazole using targeted sparse sampling and scavenged samples from infants that were ≤32 weeks of gestational age at birth and <120 postnatal days. A 5-center study was performed. A population PK model using nonlinear mixed-effect modeling (NONMEM) was developed. Covariate effects were evaluated based on estimated precision and clinical significance. Using the individual Bayesian PK estimates from the final population PK model and the dosing regimen used for each subject, the proportion of subjects achieving the therapeutic target of trough concentrations >8 mg/liter was calculated. Monte Carlo simulations were performed to evaluate the adequacy of different dosing recommendations per gestational age group. Thirty-two preterm infants were enrolled: the median (range) gestational age at birth was 27 (22 to 32) weeks, postnatal age was 41 (0 to 97) days, postmenstrual age (PMA) was 32 (24 to 43) weeks, and weight was 1,495 (678 to 3,850) g. The final PK data set contained 116 samples; 104/116 (90%) were scavenged from discarded clinical specimens. Metronidazole population PK was best described by a 1-compartment model. The population mean clearance (CL; liter/h) was determined as 0.0397 × (weight/1.5) × (PMA/32)2.49 using a volume of distribution (V) (liter) of 1.07 × (weight/1.5). The relative standard errors around parameter estimates ranged between 11% and 30%. On average, metronidazole concentrations in scavenged samples were 30% lower than those measured in scheduled blood draws. The majority of infants (>70%) met predefined pharmacodynamic efficacy targets. A new, simplified, postmenstrual-age-based dosing regimen is recommended for this population. Minimal-risk methods such as scavenged PK sampling provided meaningful information related to development of metronidazole PK models and dosing recommendations. PMID:22252819
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Using remotely-sensed multispectral imagery to build age models for alluvial fan surfaces
NASA Astrophysics Data System (ADS)
D'Arcy, Mitch; Mason, Philippa J.; Roda Boluda, Duna C.; Whittaker, Alexander C.; Lewis, James
2016-04-01
Accurate exposure age models are essential for much geomorphological field research, and generally depend on laboratory analyses such as radiocarbon, cosmogenic nuclide, or luminescence techniques. These approaches continue to revolutionise geomorphology, however they cannot be deployed remotely or in situ in the field. Therefore other methods are still needed for producing preliminary age models, performing relative dating of surfaces, or selecting sampling sites for the laboratory analyses above. With the widespread availability of detailed multispectral imagery, a promising approach is to use remotely-sensed data to discriminate surfaces with different ages. Here, we use new Landsat 8 Operational Land Imager (OLI) multispectral imagery to characterise the reflectance of 35 alluvial fan surfaces in the semi-arid Owens Valley, California. Alluvial fans are useful landforms to date, as they are widely used to study the effects of tectonics, climate and sediment transport processes on source-to-sink sedimentation. Our target fan surfaces have all been mapped in detail in the field, and have well-constrained exposure ages ranging from modern to ~ 125 ka measured using a high density of 10Be cosmogenic nuclide samples. Despite all having similar granitic compositions, the spectral properties of these surfaces vary systematically with their exposure ages. Older surfaces demonstrate a predictable shift in reflectance across the visible and short-wave infrared spectrum. Simple calculations, such as the brightness ratios of different wavelengths, generate sensitive power law relationships with exposure age that depend on post-depositional alteration processes affecting these surfaces. We investigate what these processes might be in this dryland location, and evaluate the potential for using remotely-sensed multispectral imagery for developing surface age models. The ability to remotely sense relative exposure ages has useful implications for preliminary mapping, selecting sampling sites for laboratory-based exposure age techniques, and correlating existing age constraints to un-sampled surfaces.
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A new model for ancient DNA decay based on paleogenomic meta-analysis
Ware, Roselyn; Smith, Oliver; Collins, Matthew
2017-01-01
Abstract The persistence of DNA over archaeological and paleontological timescales in diverse environments has led to a revolutionary body of paleogenomic research, yet the dynamics of DNA degradation are still poorly understood. We analyzed 185 paleogenomic datasets and compared DNA survival with environmental variables and sample ages. We find cytosine deamination follows a conventional thermal age model, but we find no correlation between DNA fragmentation and sample age over the timespans analyzed, even when controlling for environmental variables. We propose a model for ancient DNA decay wherein fragmentation rapidly reaches a threshold, then subsequently slows. The observed loss of DNA over time may be due to a bulk diffusion process in many cases, highlighting the importance of tissues and environments creating effectively closed systems for DNA preservation. This model of DNA degradation is largely based on mammal bone samples due to published genomic dataset availability. Continued refinement to the model to reflect diverse biological systems and tissue types will further improve our understanding of ancient DNA breakdown dynamics. PMID:28486705
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Ahmed, Tamer; Filiatrault, Johanne; Yu, Hsiu-Ting; Zunzunegui, Maria Victoria
2017-01-01
Abstract Purpose: Active aging is a concept that lacks consensus. The WHO defines it as a holistic concept that encompasses the overall health, participation, and security of older adults. Fernández-Ballesteros and colleagues propose a similar concept but omit security and include mood and cognitive function. To date, researchers attempting to validate conceptual models of active aging have obtained mixed results. The goal of this study was to examine the validity of existing models of active aging with epidemiological data from Canada. Methods: The WHO model of active aging and the psychological model of active aging developed by Fernández-Ballesteros and colleagues were tested with confirmatory factor analysis. The data used included 799 community-dwelling older adults between 65 and 74 years old, recruited from the patient lists of family physicians in Saint-Hyacinthe, Quebec and Kingston, Ontario. Results: Neither model could be validated in the sample of Canadian older adults. Although a concept of healthy aging can be modeled adequately, social participation and security did not fit a latent factor model. A simple binary index indicated that 27% of older adults in the sample did not meet the active aging criteria proposed by the WHO. Implications: Our results suggest that active aging might represent a human rights policy orientation rather than an empirical measurement tool to guide research among older adult populations. Binary indexes of active aging may serve to highlight what remains to be improved about the health, participation, and security of growing populations of older adults. PMID:26350153
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Excellent amino acid racemization results from Holocene sand dollars
NASA Astrophysics Data System (ADS)
Kosnik, M.; Kaufman, D. S.; Kowalewski, M.; Whitacre, K.
2015-12-01
Amino acid racemization (AAR) is widely used as a cost-effective method to date molluscs in time-averaging and taphonomic studies, but it has not been attempted for echinoderms despite their paleobiological importance. Here we demonstrate the feasibility of AAR geochronology in Holocene aged Peronella peronii (Echinodermata: Echinoidea) collected from Sydney Harbour (Australia). Using standard HPLC methods we determined the extent of AAR in 74 Peronella tests and performed replicate analyses on 18 tests. We sampled multiple areas of two individuals and identified the outer edge as a good sampling location. Multiple replicate analyses from the outer edge of 18 tests spanning the observed range of D/Ls yielded median coefficients of variation < 4% for Asp, Phe, Ala, and Glu D/L values, which overlaps with the analytical precision. Correlations between D/L values across 155 HPLC injections sampled from 74 individuals are also very high (pearson r2 > 0.95) for these four amino acids. The ages of 11 individuals spanning the observed range of D/L values were determined using 14C analyses, and Bayesian model averaging was used to determine the best AAR age model. The averaged age model was mainly composed of time-dependent reaction kinetics models (TDK, 71%) based on phenylalanine (Phe, 94%). Modelled ages ranged from 14 to 5539 yrs, and the median 95% confidence interval for the 74 analysed individuals is ±28% of the modelled age. In comparison, the median 95% confidence interval for the 11 calibrated 14C ages was ±9% of the median age estimate. Overall Peronella yields exceptionally high-quality AAR D/L values and appears to be an excellent substrate for AAR geochronology. This work opens the way for time-averaging and taphonomic studies of echinoderms similar to those in molluscs.
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Predicting Word Maturity from Frequency and Semantic Diversity: A Computational Study
ERIC Educational Resources Information Center
Jorge-Botana, Guillermo; Olmos, Ricardo; Sanjosé, Vicente
2017-01-01
Semantic word representation changes over different ages of childhood until it reaches its adult form. One method to formally model this change is the word maturity paradigm. This method uses a text sample for each age, including adult age, and transforms the samples into a semantic space by means of Latent Semantic Analysis. The representation of…
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Growth rates of young-of-year shovelnose sturgeon in the Upper Missouri River
Braaten, P. J.; Fuller, D.B.
2007-01-01
Information on growth during the larval and young-of-year life stages in natural river environments is generally lacking for most sturgeon species. In this study, methods for estimating ages and quantifying growth were developed for field-sampled larval and young-of-year shovelnose sturgeon Scaphirhynchus platorynchus in the upper Missouri River. First, growth was assessed by partitioning samples of young-of-year shovelnose sturgeon into cohorts, and regressing weekly increases in cohort mean length on sampling date. This method quantified relative growth because ages of the cohorts were unknown. Cohort increases in mean length among sampling dates were positively related (P < 0.05, r2 > 0.59 for all cohorts) to sampling date, and yielded growth rate estimates of 0.80–2.95 mm day−1 (2003) and 0.44–2.28 mm day−1 (2004). Highest growth rates occurred in the largest (and earliest spawned) cohorts. Second, a method was developed to estimate cohort hatch dates, thus age on date of sampling could be determined. This method included quantification of post-hatch length increases as a function of water temperature (growth capacity; mm per thermal unit, mm TU−1), and summation of mean daily water temperatures to achieve the required number of thermal units that corresponded to post-hatch lengths of shovelnose sturgeon on sampling dates. For six of seven cohorts of shovelnose sturgeon analyzed, linear growth models (r2 ≥ 0.65, P < 0.0001) or Gompertz growth models (r2 ≥ 0.83, P < 0.0001) quantified length-at-age from hatch through 55 days post-hatch (98–100 mm). Comparisons of length-at-age derived from the growth models indicated that length-at-age was greater for the earlier-hatched cohorts than later-hatched cohorts. Estimated hatch dates for different cohorts were corroborated based on the dates that newly-hatched larval shovelnose sturgeon were sampled in the drift. These results provide the first quantification of growth dynamics for field-sampled age-0 shovelnose sturgeon in a natural river environment, and provide an accurate method for estimating age of wild-caught individuals. Methods of age determination used in this study have applications to sturgeons in other regions, but require additional testing and validation.
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Chen, Ying; Pham, Tuan D
2013-05-15
We apply for the first time the sample entropy (SampEn) and regularity dimension model for measuring signal complexity to quantify the structural complexity of the brain on MRI. The concept of the regularity dimension is based on the theory of chaos for studying nonlinear dynamical systems, where power laws and entropy measure are adopted to develop the regularity dimension for modeling a mathematical relationship between the frequencies with which information about signal regularity changes in various scales. The sample entropy and regularity dimension of MRI-based brain structural complexity are computed for early Alzheimer's disease (AD) elder adults and age and gender-matched non-demented controls, as well as for a wide range of ages from young people to elder adults. A significantly higher global cortical structure complexity is detected in AD individuals (p<0.001). The increase of SampEn and the regularity dimension are also found to be accompanied with aging which might indicate an age-related exacerbation of cortical structural irregularity. The provided model can be potentially used as an imaging bio-marker for early prediction of AD and age-related cognitive decline. Copyright © 2013 Elsevier B.V. All rights reserved.
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ERIC Educational Resources Information Center
Serry, Tanya Anne; Castles, Anne; Mensah, Fiona K.; Bavin, Edith L.; Eadie, Patricia; Pezic, Angela; Prior, Margot; Bretherton, Lesley; Reilly, Sheena
2015-01-01
The paper reports on a study designed to develop a risk model that can best predict single-word spelling in seven-year-old children when they were aged 4 and 5. Test measures, personal characteristics and environmental influences were all considered as variables from a community sample of 971 children. Strong concurrent correlations were found…
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Vidaki, Athina; Ballard, David; Aliferi, Anastasia; Miller, Thomas H; Barron, Leon P; Syndercombe Court, Denise
2017-05-01
The ability to estimate the age of the donor from recovered biological material at a crime scene can be of substantial value in forensic investigations. Aging can be complex and is associated with various molecular modifications in cells that accumulate over a person's lifetime including epigenetic patterns. The aim of this study was to use age-specific DNA methylation patterns to generate an accurate model for the prediction of chronological age using data from whole blood. In total, 45 age-associated CpG sites were selected based on their reported age coefficients in a previous extensive study and investigated using publicly available methylation data obtained from 1156 whole blood samples (aged 2-90 years) analysed with Illumina's genome-wide methylation platforms (27K/450K). Applying stepwise regression for variable selection, 23 of these CpG sites were identified that could significantly contribute to age prediction modelling and multiple regression analysis carried out with these markers provided an accurate prediction of age (R 2 =0.92, mean absolute error (MAE)=4.6 years). However, applying machine learning, and more specifically a generalised regression neural network model, the age prediction significantly improved (R 2 =0.96) with a MAE=3.3 years for the training set and 4.4 years for a blind test set of 231 cases. The machine learning approach used 16 CpG sites, located in 16 different genomic regions, with the top 3 predictors of age belonged to the genes NHLRC1, SCGN and CSNK1D. The proposed model was further tested using independent cohorts of 53 monozygotic twins (MAE=7.1 years) and a cohort of 1011 disease state individuals (MAE=7.2 years). Furthermore, we highlighted the age markers' potential applicability in samples other than blood by predicting age with similar accuracy in 265 saliva samples (R 2 =0.96) with a MAE=3.2 years (training set) and 4.0 years (blind test). In an attempt to create a sensitive and accurate age prediction test, a next generation sequencing (NGS)-based method able to quantify the methylation status of the selected 16 CpG sites was developed using the Illumina MiSeq ® platform. The method was validated using DNA standards of known methylation levels and the age prediction accuracy has been initially assessed in a set of 46 whole blood samples. Although the resulted prediction accuracy using the NGS data was lower compared to the original model (MAE=7.5years), it is expected that future optimization of our strategy to account for technical variation as well as increasing the sample size will improve both the prediction accuracy and reproducibility. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.
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NASA Astrophysics Data System (ADS)
Kanamatsu, Toshiya; Usami, Kazuko; McHugh, Cecilia M. G.; Ikehara, Ken
2017-08-01
Using high-resolution paleomagnetic data, we examined the potential for obtaining precise ages from sediment core samples recovered from deep-sea basins close to rupture zones of the 2011 and earlier earthquakes off Tohoku, Japan. Obtaining detailed stratigraphic ages from deep-sea sediments below the calcium compensation depth (CCD) is difficult, but we found that the samples contain excellent paleomagnetic secular variation records to constrain age models. Variations in paleomagnetic directions obtained from the sediments reveal systematic changes in the cores. A stacked paleomagnetic profile closely matches the Lake Biwa data sets in southwest Japan for the past 7000 years, one can establish age models based on secular variations of the geomagnetic field on sediments recovered uniquely below the CCD. Comparison of paleomagnetic directions near a tephra and a paleomagnetic direction of contemporaneous pyroclastic flow deposits acquired by different magnetization processes shows precise depositional ages reflecting the magnetization delay of the marine sediment record.
Plain Language SummaryGenerally obtaining detailed ages from deep-sea sediments is difficult, because available dating method is very limited. We found that the deep-see sediment off North Japan recorded past sequential geomagnetic directions. If those records correlate well with the reference record in past 7000 years, then we could estimate age of sediment by pattern matching. Additionally a volcanic ash emitted in 915 A.D., which was intercalated in our samples, indicates a time lag in our age model. This observation makes our age model more precise.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22212006','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22212006"><span>Using the Johns Hopkins' Aggregated Diagnosis Groups (ADGs) to predict 1-year mortality in population-based cohorts of patients with diabetes in Ontario, Canada.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Austin, P C; Shah, B R; Newman, A; Anderson, G M</p> <p>2012-09-01</p> <p>There are limited validated methods to ascertain comorbidities for risk adjustment in ambulatory populations of patients with diabetes using administrative health-care databases. The objective was to examine the ability of the Johns Hopkins' Aggregated Diagnosis Groups to predict mortality in population-based ambulatory samples of both incident and prevalent subjects with diabetes. Retrospective cohorts constructed using population-based administrative data. The incident cohort consisted of all 346,297 subjects diagnosed with diabetes between 1 April 2004 and 31 March 2008. The prevalent cohort consisted of all 879,849 subjects with pre-existing diabetes on 1 January, 2007. The outcome was death within 1 year of the subject's index date. A logistic regression model consisting of age, sex and indicator variables for 22 of the 32 Johns Hopkins' Aggregated Diagnosis Group categories had excellent discrimination for predicting mortality in incident diabetes patients: the c-statistic was 0.87 in an independent validation sample. A similar model had excellent discrimination for predicting mortality in prevalent diabetes patients: the c-statistic was 0.84 in an independent validation sample. Both models demonstrated very good calibration, denoting good agreement between observed and predicted mortality across the range of predicted mortality in which the large majority of subjects lay. For comparative purposes, regression models incorporating the Charlson comorbidity index, age and sex, age and sex, and age alone had poorer discrimination than the model that incorporated the Johns Hopkins' Aggregated Diagnosis Groups. Logistical regression models using age, sex and the John Hopkins' Aggregated Diagnosis Groups were able to accurately predict 1-year mortality in population-based samples of patients with diabetes. © 2011 The Authors. Diabetic Medicine © 2011 Diabetes UK.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26350153','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26350153"><span>An Empirical Comparison of Different Models of Active Aging in Canada: The International Mobility in Aging Study.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bélanger, Emmanuelle; Ahmed, Tamer; Filiatrault, Johanne; Yu, Hsiu-Ting; Zunzunegui, Maria Victoria</p> <p>2017-04-01</p> <p>Active aging is a concept that lacks consensus. The WHO defines it as a holistic concept that encompasses the overall health, participation, and security of older adults. Fernández-Ballesteros and colleagues propose a similar concept but omit security and include mood and cognitive function. To date, researchers attempting to validate conceptual models of active aging have obtained mixed results. The goal of this study was to examine the validity of existing models of active aging with epidemiological data from Canada. The WHO model of active aging and the psychological model of active aging developed by Fernández-Ballesteros and colleagues were tested with confirmatory factor analysis. The data used included 799 community-dwelling older adults between 65 and 74 years old, recruited from the patient lists of family physicians in Saint-Hyacinthe, Quebec and Kingston, Ontario. Neither model could be validated in the sample of Canadian older adults. Although a concept of healthy aging can be modeled adequately, social participation and security did not fit a latent factor model. A simple binary index indicated that 27% of older adults in the sample did not meet the active aging criteria proposed by the WHO. Our results suggest that active aging might represent a human rights policy orientation rather than an empirical measurement tool to guide research among older adult populations. Binary indexes of active aging may serve to highlight what remains to be improved about the health, participation, and security of growing populations of older adults. © The Author 2015. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27182964','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27182964"><span>Admixture analysis of age at onset in first episode bipolar disorder.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Nowrouzi, Behdin; McIntyre, Roger S; MacQueen, Glenda; Kennedy, Sidney H; Kennedy, James L; Ravindran, Arun; Yatham, Lakshmi; De Luca, Vincenzo</p> <p>2016-09-01</p> <p>Many studies have used the admixture analysis to separate age-at-onset (AAO) subgroups in bipolar disorder, but none of them examined first episode patients. The purpose of this study was to investigate the influence of clinical variables on AAO in first episode bipolar patients. The admixture analysis was applied to identify the model best fitting the observed AAO distribution of a sample of 194 patients with DSM-IV diagnosis of bipolar disorder and the finite mixture model was applied to assess the effect of clinical covariates on AAO. Using the BIC method, the model that was best fitting the observed distribution of AAO was a mixture of three normal distributions. We identified three AAO groups: early age-at-onset (EAO) (µ=18.0, σ=2.88), intermediate-age-at-onset (IAO) (µ=28.7, σ=3.5), and late-age-at-onset (LAO) (µ=47.3, σ=7.8), comprising 69%, 22%, and 9% of the sample respectively. Our first episode sample distribution model was significantly different from most of the other studies that applied the mixture analysis. The main limitation is that our sample may have inadequate statistical power to detect the clinical associations with the AAO subgroups. This study confirms that bipolar disorder can be classified into three groups based on AAO distribution. The data reported in our paper provide more insight into the diagnostic heterogeneity of bipolar disorder across the three AAO subgroups. Copyright © 2016 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017EGUGA..19.5137M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017EGUGA..19.5137M"><span>Improving age-depth models using sedimentary proxies for accumulation rates in fluvio-lacustrine deposits</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Minderhoud, Philip S. J.; Cohen, Kim M.; Toonen, Willem. H. J.; Erkens, Gilles; Hoek, Wim Z.</p> <p>2017-04-01</p> <p>Lacustrine fills, including those of oxbow lakes in river floodplains, often hold valuable sedimentary and biological proxy records of palaeo-environmental change. Precise dating of accumulated sediments at levels throughout these records is crucial for interpretation and correlation of (proxy) data existing within the fills. Typically, dates are gathered from multiple sampled levels and their results are combined in age-depth models to estimate the ages of events identified between the datings. In this paper, a method of age-depth modelling is presented that varies the vertical accumulation rate of the lake fill based on continuous sedimentary data. In between Bayesian calibrated radiocarbon dates, this produces a modified non-linear age-depth relation based on sedimentology rather than linear or spline interpolation. The method is showcased on a core of an infilled palaeomeander at the floodplain edge of the river Rhine near Rheinberg (Germany). The sequence spans from 4.7 to 2.9 ka cal BP and consists of 5.5 meters of laminated lacustrine, organo-clastic mud, covered by 1 meter of peaty clay. Four radiocarbon dates provide direct dating control, mapping and dating in the wider surroundings provide additional control. The laminated, organo-clastic facies of the oxbow fill contains a record of nearby fluvial-geomorphological activity, including meander reconfiguration events and passage of rare large floods, recognized as fluctuations in coarseness and amount of allochthonous clastic sediment input. Continuous along-core sampling and measurement of loss-on-ignition (LOI) provided a fast way of expressing the variation in clastic sedimentation influx from the nearby river versus autochthonous organic deposition derived from biogenic production in the lake itself. This low-cost sedimentary proxy data feeds into the age-depth modelling. The sedimentology-modelled age-depth relation (re)produces the distinct lithological boundaries in the fill as marked changes in sedimentation rate. Especially the organo-clastic muddy facies subdivides in centennial intervals of relative faster and slower accumulation. For such intervals, sedimentation rates are produced that deviate 10 to 20% from that in simpler stepped linear age-models. For irregularly laminated muddy intervals of the oxbow fill - from which meaningful sampling for radiocarbon dating is more difficult than from peaty or slowly accumulating organic lake sediments - supplementing spotty radiocarbon sampling with continuous sedimentary proxy data creates more realistic age-depth modelling results.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_1");'>1</a></li> <li class="active"><span>2</span></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_2 --> <div id="page_3" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_1");'>1</a></li> <li><a href="#" onclick='return showDiv("page_2");'>2</a></li> <li class="active"><span>3</span></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="41"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016PhDT.......134B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016PhDT.......134B"><span>A Tale of Two Earths: Reconciling the Lunar and Terrestrial Hadean Records</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Boehnke, Patrick</p> <p></p> <p>Studying early Earth history is complicated by the fact that the rock record doesn't extend past 4 Ga and our only record for the Hadean (>4 Ga) comes to us from detrital zircons from the Jack Hills in Western Australia. The Hadean zircon record extends back to almost 4.4 Ga and has revealed that the early Earth may have had liquid water, a felsic crust, plate boundary interactions, and possibly a biosphere. On the other hand, analyses of lunar and meteoritic samples are used to argue for a hellish Hadean Earth where frequent, large impactors repeatedly destroyed the crust. Indeed, these two models stand in direct contradiction. The focus of this thesis is to examine the evidence for these two models and ultimately propose a reconciliation based on a new interpretation of the chronology of the lunar samples used to constrain the impact history into the early Earth-Moon system. In order to improve the understanding of zircon crystallization in igneous settings, we undertook experimental studies of zircon saturation which were analyzed using a novel ion imaging approach by a secondary ion mass spectrometer. This study confirmed the original model for zircon saturation, that it is a function of only temperature, melt composition, and Zr content. Indeed, the primary implication for the early Earth from this work is that zircons are much more likely to crystallize in a felsic rather than mafic magma and therefore simply the existence of Hadean zircons suggests a high likelihood for felsic Hadean magmatism. The majority of the thesis focuses on the interpretation of 40 Ar/39Ar ages of lunar and meteorite samples, specifically with regards to impact histories derived from compilations of such ages. The primary complication with lunar and meteorite 40Ar/ 39Ar ages is that the vast majority show evidence for later disturbances due to diffusive loss of 40Ar. To try and extract meaningful thermal histories from these samples, we undertook investigations of samples from Apollo 16 and the Jilin chondrite. We then used an extension of the multi-domain diffusion model that can model samples containing multiple activation energies (i.e., whole rock samples with multiple K bearing minerals) to propose that the 40Ar/39Ar system can be used to recover shock heating temperatures and durations. Having shown the effects of diffusive 40Ar loss on the accuracy of 40Ar/39Ar dating, we then explored the question as to whether or not compilations of disturbed 40Ar/ 39Ar ages simply misestimate the timing of bombardment episodes or are fundamentally inaccurate. For this we created a simple numerical model that simulates a chosen impact history on a surface and then creates a histogram of 40Ar/39Ar plateau ages. Our results show that rather than simply misestimate timing, compilations of 40Ar/ 39Ar ages can lead to inferences of illusory bombardment episodes. Finally, we examine the 40Ar/39Ar ages of suite of geochemically related Apollo 16 rocks to examine the effects of mixing and brecciation on the accuracy of inferred ages. By analyzing multiple rocks from each soil sample, we show that three out of six samples are not compatible with a single thermal history. That is to say, despite their close proximity during sampling and geochemical similarities, analyzed rocks in the soil sample have unique chronologies. Based on these findings, we developed a simple numerical model which shows that internal isochrons of mixed samples can yield erroneous ages while retaining a statistically acceptable mean squared weighted deviation (MSWD).</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70187207','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70187207"><span>Age, growth and fall diet of channel catfish in Cheat Lake, West Virginia</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Hilling, Corbin D.; Welsh, Stuart A.; Smith, Dustin M.</p> <p>2016-01-01</p> <p>Acidification has historically impaired Cheat Lake's fish community, but recent mitigation efforts within the Cheat River watershed have improved water quality and species richness. Presently, channel catfish Ictalurus punctatus are abundant and attain desirable sizes for anglers. We evaluated the age, growth, and fall diet of the population. We collected a sample of 155 channel catfish from Cheat Lake from 5 August to 4 December 2014, a subset of which we aged (n = 148) using lapillus otoliths. We fit four growth models (von Bertalanffy, logistic, Gompertz, and power) to length-at-age data and compared models using an information theoretic approach. We collected fall diets from 55 fish sampled from 13 October to 4 December 2014. Total lengths of individuals in the sample ranged from 154 to 721 mm and ages ranged from 2 to 19 y. We AICc-selected the von Bertalanffy growth model as the best approximating model, and the power and Gompertz models also had considerable support. Diets were numerically dominated by Diptera larvae, specifically Chironomidae and Chaoboridae, while 39% of stomachs contained terrestrial food items. This study provides baseline data for management of Cheat Lake's channel catfish population. Further, this study fills a knowledge gap in the scientific literature on channel catfish, because few previously published studies have examined the population ecology of channel catfish in the Central Appalachian region.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19890008969','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19890008969"><span>Absolute ages from crater statistics: Using radiometric ages of Martian samples for determining the Martian cratering chronology</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Neukum, G.</p> <p>1988-01-01</p> <p>In the absence of dates derived from rock samples, impact crater frequencies are commonly used to date Martian surface units. All models for absolute dating rely on the lunar cratering chronology and on the validity of its extrapolation to Martian conditions. Starting from somewhat different lunar chronologies, rather different Martian cratering chronologies are found in the literature. Currently favored models are compared. The differences at old ages are significant, the differences at younger ages are considerable and give absolute ages for the same crater frequencies as different as a factor of 3. The total uncertainty could be much higher, though, since the ratio of lunar to Martian cratering rate which is of basic importance in the models is believed to be known no better than within a factor of 2. Thus, it is of crucial importance for understanding the the evolution of Mars and determining the sequence of events to establish an unambiguous Martian cratering chronology from crater statistics in combination with clean radiometric ages of returned Martian samples. For the dating goal, rocks should be as pristine as possible from a geologically simple area with a one-stage emplacement history of the local formation. A minimum of at least one highland site for old ages, two intermediate-aged sites, and one very young site is needed.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15776979','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15776979"><span>Age of first use and ongoing patterns of legal and illegal drug use in a sample of young Londoners.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>McCambridge, Jim; Strang, John</p> <p>2005-01-01</p> <p>The significance of ages of first use of cigarettes, alcohol, cannabis, and stimulant drugs were investigated in a sample of young drug users entering an intervention study in London. Age of first cigarette smoking emerges as a robust predictor of age of first cannabis use, and age of first cannabis use in turn is predictive of age of first stimulant use, among those using both drugs. In this sample, ages of first use of cigarettes, alcohol, and cannabis are not predictive of whether stimulant drugs are used. In a series of regression models that take account of the influence of other factors, age of first use is found to have no relationship to levels of ongoing consumption of cigarettes, alcohol, and cannabis.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28594191','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28594191"><span>Overgeneral autobiographical memory in healthy young and older adults: Differential age effects on components of the capture and rumination, functional avoidance, and impaired executive control (CaRFAX) model.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ros, Laura; Latorre, Jose M; Serrano, Juan P; Ricarte, Jorge J</p> <p>2017-08-01</p> <p>The CaRFAX model (Williams et al., 2007) has been used to explain the causes of overgeneral autobiographical memory (OGM; the difficulty to retrieve specific autobiographical memories), a cognitive phenomenon generally related with different psychopathologies. This model proposes 3 different mechanisms to explain OGM: capture and rumination (CaR), functional avoidance (FA) and impaired executive functions (X). However, the complete CaRFAX model has not been tested in nonclinical populations. This study aims to assess the usefulness of the CaRFAX model to explain OGM in 2 healthy samples: a young sample and an older sample, to test for possible age-related differences in the underlying causes of OGM. A total of 175 young (age range: 19-36 years) and 175 older (age range: 53-88 years) participants completed measures of brooding rumination (CaR), functional avoidance (FA), and executive tasks (X). Using structural equation modeling, we found that memory specificity is mainly associated with lower functional avoidance and higher executive functions in the older group, but only with executive functions in young participants. We discuss the different roles of emotional regulation strategies used by young and older people and their relation to the CaRFAX model to explain OGM in healthy people. (PsycINFO Database Record (c) 2017 APA, all rights reserved).</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28486705','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28486705"><span>A new model for ancient DNA decay based on paleogenomic meta-analysis.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kistler, Logan; Ware, Roselyn; Smith, Oliver; Collins, Matthew; Allaby, Robin G</p> <p>2017-06-20</p> <p>The persistence of DNA over archaeological and paleontological timescales in diverse environments has led to a revolutionary body of paleogenomic research, yet the dynamics of DNA degradation are still poorly understood. We analyzed 185 paleogenomic datasets and compared DNA survival with environmental variables and sample ages. We find cytosine deamination follows a conventional thermal age model, but we find no correlation between DNA fragmentation and sample age over the timespans analyzed, even when controlling for environmental variables. We propose a model for ancient DNA decay wherein fragmentation rapidly reaches a threshold, then subsequently slows. The observed loss of DNA over time may be due to a bulk diffusion process in many cases, highlighting the importance of tissues and environments creating effectively closed systems for DNA preservation. This model of DNA degradation is largely based on mammal bone samples due to published genomic dataset availability. Continued refinement to the model to reflect diverse biological systems and tissue types will further improve our understanding of ancient DNA breakdown dynamics. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012AGUFM.P42A..10C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012AGUFM.P42A..10C"><span>The Violent Early Solar System, as Told by Lunar Sample Geochronology</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Cohen, B. A.</p> <p>2012-12-01</p> <p>One of the legacies of the samples collected by the Apollo and Luna missions is the link forged between radiometric ages of rocks and relative ages according to stratigraphic relationships and impact crater size-frequency distributions. Our current understanding of the history of the inner solar system is based on the relative chronology of individual planets, tied to the absolute geochronology of the Moon via these important samples. Sample ages have enabled us to infer that impact-melt breccias from Apollo 14 and 15 record the formation of the Imbrium Basin, those from the highland massifs at Apollo 17 record the age of Serenitatis, those from the KREEP-poor Apollo 16 site record the age of Nectaris, and materials from Luna 24 record the age of Crisium. Ejecta from smaller and younger craters Copernicus and Tycho were sampled at Apollo 12 and 17, respectively, and local craters such as Cone at Apollo 14, and North Ray and South Ray at Apollo 16 were also sampled and ages determined for those events. Much of what we understand about the lunar impact flux is based on these ages. Samples from these nearside locations reveal a preponderance of impact-disturbed or recrystallized ages between 3.75 and 3.95 billion years. Argon and lead loss (and correlated disturbances in the Rb-Sr system) have been attributed to metamorphism of the lunar crust by an enormous number of impacts in a brief pulse of time, called the Lunar Cataclysm or Late Heavy Bombardment. Subsequent high-precision geochronometric analyses of Apollo samples and lunar highlands meteorites show a wider range of ages, but very few older than 4 Ga. The paucity of ancient impact melt rocks has been interpreted to mean that either that most impact basins formed at this time, or that ejecta from the large, near-side, young basins dominates the Apollo samples. The impact history of the Moon has significant implications because the lunar bombardment history mirrors that of the Earth. During the cataclysm, 80% of the lunar surface was resurfaced; on Earth, this would scale to ~23,000 large impacts in a brief time. Impact ages in ordinary chondrites, HED meteorites, and the Martian meteorite ALH 84001 suggest that this early bombardment event affected the entire inner solar system. If true, the late heavy bombardment may have directly affected the evolution of life on Earth and our understanding of "habitable" planets. Lunar sample ages have also been used to drive large-scale dynamical modeling of solar system formation. These new models of planetary dynamics show a violent beginning to our solar system, where the late formation or outward migration of the gas giant planets destabilizes the Kuiper belt and main-belt asteroids, sending a cascade of impactors into the Moon and all the inner planets. The existence of an early bombardment has even been postulated in extrasolar planetary systems. Even after 40+ years of study, the provenance of returned lunar samples and ages of key events continue to be a focus of research and a topic of debate. One of the most important lessons learned from Apollo missions is that small samples yield a wealth of information and are gifts that keep on giving. The legacy of Apollo samples serves as a model and impetus for future sample return missions from the Moon, Mars, and asteroids.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23892055','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23892055"><span>The effects of temperature and diet on age grading and population age structure determination in Drosophila.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Aw, Wen C; Ballard, J William O</p> <p>2013-10-01</p> <p>The age structure of natural population is of interest in physiological, life history and ecological studies but it is often difficult to determine. One methodological problem is that samples may need to be invasively sampled preventing subsequent taxonomic curation. A second problem is that it can be very expensive to accurately determine the age structure of given population because large sample sizes are often necessary. In this study, we test the effects of temperature (17 °C, 23 °C and 26 °C) and diet (standard cornmeal and low calorie diet) on the accuracy of the non-invasive, inexpensive and high throughput near-infrared spectroscopy (NIRS) technique to determine the age of Drosophila flies. Composite and simplified calibration models were developed for each sex. Independent sets for each temperature and diet treatments with flies not involved in calibration model were then used to validate the accuracy of the calibration models. The composite NIRS calibration model was generated by including flies reared under all temperatures and diets. This approach permits rapid age measurement and age structure determination in large population of flies as less than or equal to 9 days, or more than 9 days old with 85-97% and 64-99% accuracy, respectively. The simplified calibration models were generated by including flies reared at 23 °C on standard diet. Low accuracy rates were observed when simplified calibration models were used to identify (a) Drosophila reared at 17 °C and 26 °C and (b) 23 °C with low calorie diet. These results strongly suggest that appropriate calibration models need to be developed in the laboratory before this technique can be reliably used in field. These calibration models should include the major environmental variables that change across space and time in the particular natural population to be studied. Copyright © 2013 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70047464','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70047464"><span>Late Quaternary sedimentological and climate changes at Lake Bosumtwi Ghana: new constraints from laminae analysis and radiocarbon age modeling</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Shanahan, Timothy M.; Beck, J. Warren; Overpeck, Jonathan T.; McKay, Nicholas P.; Pigati, Jeffrey S.; Peck, John A.; Scholz, Christopher A.; Heil, Clifford W.; King, John W.</p> <p>2012-01-01</p> <p>The Lake Bosumtwi sediment record represents one of the longest and highest-resolution terrestrial records of paleoclimate change available from sub-Saharan Africa. Here we report a new sediment age model framework for the last ~ 45 cal kyr of sedimentation using a combination of high-resolution radiocarbon dating, Bayesian age-depth modeling and lamination counting. Our results highlight the practical limits of these methods for reducing age model uncertainties and suggest that even with very high sampling densities, radiocarbon uncertainties of at least a few hundred years are unavoidable. Age model uncertainties are smallest during the Holocene (205 yr) and the glacial (360 yr) but are large at the base of the record (1660 yr), due to a combination of decreasing sample density, larger calibration uncertainties and increases in radiocarbon age scatter. For portions of the chronology older than ~ 35 cal kyr, additional considerations, such as the use of a low-blank graphitization system and more rigorous sample pretreatment were necessary to generate a reliable age depth model because of the incorporation of small amounts of younger carbon. A comparison of radiocarbon age model results and lamination counts over the time interval ~ 15–30 cal kyr agree with an overall discrepancy of ~ 10% and display similar changes in sedimentation rate, supporting the annual nature of sediment laminations in the early part of the record. Changes in sedimentation rates reconstructed from the age-depth model indicate that intervals of enhanced sediment delivery occurred at 16–19, 24 and 29–31 cal kyr, broadly synchronous with reconstructed drought episodes elsewhere in northern West Africa and potentially, with changes in Atlantic meridional heat transport during North Atlantic Heinrich events. These data suggest that millennial-scale drought events in the West African monsoon region were latitudinally extensive, reaching within several hundred kilometers of the Guinea coast. This is inconsistent with a simple southward shift in the mean position of the monsoon rainbelt, and requires changes in moisture convergence as a result of either a reduction in the moisture content of the tropical rainbelt, decreased convection, or both.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1438644-prediction-precipitation-strengthening-commercial-mg-alloy-az91-using-dislocation-dynamics','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1438644-prediction-precipitation-strengthening-commercial-mg-alloy-az91-using-dislocation-dynamics"><span>Prediction of Precipitation Strengthening in the Commercial Mg Alloy AZ91 Using Dislocation Dynamics</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a></p> <p>Aagesen, L. K.; Miao, J.; Allison, J. E.; ...</p> <p>2018-03-05</p> <p>In this paper, dislocation dynamics simulations were used to predict the strengthening of a commercial magnesium alloy, AZ91, due to β-Mg 17Al 12 formed in the continuous precipitation mode. The precipitate distributions used in simulations were determined based on experimental characterization of the sizes, shapes, and number densities of the precipitates for 10-hour aging and 50-hour aging. For dislocations gliding on the basal plane, which is expected to be the dominant contributor to plastic deformation at room temperature, the critical resolved shear stress to bypass the precipitate distribution was 3.5 MPa for the 10-hour aged sample and 16.0 MPa formore » the 50-hour aged sample. The simulation results were compared to an analytical model of strengthening in this alloy, and the analytical model was found to predict critical resolved shear stresses that were approximately 30 pct lower. A model for the total yield strength was developed and compared with experiment for the 50-hour aged sample. Finally, the predicted yield strength, which included the precipitate strengthening contribution from the DD simulations, was 132.0 MPa, in good agreement with the measured yield strength of 141 MPa.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/1438644-prediction-precipitation-strengthening-commercial-mg-alloy-az91-using-dislocation-dynamics','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/1438644-prediction-precipitation-strengthening-commercial-mg-alloy-az91-using-dislocation-dynamics"><span>Prediction of Precipitation Strengthening in the Commercial Mg Alloy AZ91 Using Dislocation Dynamics</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Aagesen, L. K.; Miao, J.; Allison, J. E.</p> <p></p> <p>In this paper, dislocation dynamics simulations were used to predict the strengthening of a commercial magnesium alloy, AZ91, due to β-Mg 17Al 12 formed in the continuous precipitation mode. The precipitate distributions used in simulations were determined based on experimental characterization of the sizes, shapes, and number densities of the precipitates for 10-hour aging and 50-hour aging. For dislocations gliding on the basal plane, which is expected to be the dominant contributor to plastic deformation at room temperature, the critical resolved shear stress to bypass the precipitate distribution was 3.5 MPa for the 10-hour aged sample and 16.0 MPa formore » the 50-hour aged sample. The simulation results were compared to an analytical model of strengthening in this alloy, and the analytical model was found to predict critical resolved shear stresses that were approximately 30 pct lower. A model for the total yield strength was developed and compared with experiment for the 50-hour aged sample. Finally, the predicted yield strength, which included the precipitate strengthening contribution from the DD simulations, was 132.0 MPa, in good agreement with the measured yield strength of 141 MPa.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018MMTA..tmp...85A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018MMTA..tmp...85A"><span>Prediction of Precipitation Strengthening in the Commercial Mg Alloy AZ91 Using Dislocation Dynamics</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Aagesen, L. K.; Miao, J.; Allison, J. E.; Aubry, S.; Arsenlis, A.</p> <p>2018-03-01</p> <p>Dislocation dynamics simulations were used to predict the strengthening of a commercial magnesium alloy, AZ91, due to β-Mg17Al12 formed in the continuous precipitation mode. The precipitate distributions used in simulations were determined based on experimental characterization of the sizes, shapes, and number densities of the precipitates for 10-hour aging and 50-hour aging. For dislocations gliding on the basal plane, which is expected to be the dominant contributor to plastic deformation at room temperature, the critical resolved shear stress to bypass the precipitate distribution was 3.5 MPa for the 10-hour aged sample and 16.0 MPa for the 50-hour aged sample. The simulation results were compared to an analytical model of strengthening in this alloy, and the analytical model was found to predict critical resolved shear stresses that were approximately 30 pct lower. A model for the total yield strength was developed and compared with experiment for the 50-hour aged sample. The predicted yield strength, which included the precipitate strengthening contribution from the DD simulations, was 132.0 MPa, in good agreement with the measured yield strength of 141 MPa.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29340580','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29340580"><span>Population specific biomarkers of human aging: a big data study using South Korean, Canadian and Eastern European patient populations.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Mamoshina, Polina; Kochetov, Kirill; Putin, Evgeny; Cortese, Franco; Aliper, Alexander; Lee, Won-Suk; Ahn, Sung-Min; Uhn, Lee; Skjodt, Neil; Kovalchuk, Olga; Scheibye-Knudsen, Morten; Zhavoronkov, Alex</p> <p>2018-01-11</p> <p>Accurate and physiologically meaningful biomarkers for human aging are key to assessing anti-aging therapies. Given ethnic differences in health, diet, lifestyle, behaviour, environmental exposures and even average rate of biological aging, it stands to reason that aging clocks trained on datasets obtained from specific ethnic populations are more likely to account for these potential confounding factors, resulting in an enhanced capacity to predict chronological age and quantify biological age. Here we present a deep learning-based hematological aging clock modeled using the large combined dataset of Canadian, South Korean and Eastern European population blood samples that show increased predictive accuracy in individual populations compared to population-specific hematologic aging clocks. The performance of models was also evaluated on publicly-available samples of the American population from the National Health and Nutrition Examination Survey (NHANES). In addition, we explored the association between age predicted by both population-specific and combined hematological clocks and all-cause mortality. Overall, this study suggests a) the population-specificity of aging patterns and b) hematologic clocks predicts all-cause mortality. Proposed models added to the freely available Aging.AI system allowing improved ability to assess human aging. © The Author(s) 2018. Published by Oxford University Press on behalf of The Gerontological Society of America.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.fs.usda.gov/treesearch/pubs/13353','TREESEARCH'); return false;" href="https://www.fs.usda.gov/treesearch/pubs/13353"><span>Using a GIS model to assess terrestrial salamander response to alternative forest management plans</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.fs.usda.gov/treesearch/">Treesearch</a></p> <p>Eric J. Gustafson; Nathan L. Murphy; Thomas R. Crow</p> <p>2001-01-01</p> <p>A GIS model predicting the spatial distribution of terrestrial salamander abundance based on topography and forest age was developed using parameters derived from the literature. The model was tested by sampling salamander abundance across the full range of site conditions used in the model. A regression of the predictions of our GIS model against these sample data...</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.fs.usda.gov/treesearch/pubs/43492','TREESEARCH'); return false;" href="https://www.fs.usda.gov/treesearch/pubs/43492"><span>Site index model for naturally regenerated even-aged longleaf pine</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.fs.usda.gov/treesearch/">Treesearch</a></p> <p>Dwight K. Lauer; John S. Kush</p> <p>2013-01-01</p> <p>Data from the Regional Longleaf Growth Study (339 permanent sample plots) were used to develop a site index model for naturally regenerated, even-aged longleaf pine (Pinus palustris Mill.). The site index equation was derived using the generalized algebraic difference approach and is base-age invariant. Using height as a measure of site productivity...</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/1129161','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/1129161"><span>FIFTH STATUS REPORT: TESTING OF AGED SOFTWOOD FIBERBOARD MATERIAL FOR THE 9975 SHIPPING PACKAGE</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Daugherty, W.; Skidmore, E.; Dunn, K.</p> <p></p> <p>Samples have been prepared from a 9975 lower fiberboard subassembly fabricated from softwood fiberboard. Physical, mechanical and thermal properties have been measured following varying periods of conditioning in each of several environments. These tests have been conducted in the same manner as previous testing on cane fiberboard samples. Overall, similar aging trends are observed for softwood and cane fiberboard samples, with a few differences. Some softwood fiberboard properties tend to degrade faster in elevated humidity environments, while some cane fiberboard properties degrade faster in the hotter dry environments. As a result, it is premature to assume both materials will agemore » at the same rates, and the preliminary aging models developed for cane fiberboard might not apply to softwood fiberboard. However, it is expected that both cane and softwood fiberboard assemblies will perform satisfactorily in conforming packages stored in a typical KAC storage environment for up to 15 years. Aging and testing of softwood fiberboard will continue and additional data will be collected. Additional samples will be added to each aging environment, to support development of an aging model specific to softwood fiberboard. Post-conditioning data have been measured on samples from a single softwood fiberboard assembly, and baseline data are also available from a limited number of vendor-provided samples. This provides minimal information on the possible sample-to-sample variation exhibited by softwood fiberboard. Data to date are generally consistent with the range seen in cane fiberboard, but some portions of the data trends are skewed toward the lower end of that range. Two additional softwood fiberboard source packages have been obtained and will begin to provide data on the range of variability of this material.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=Volunteering&pg=6&id=EJ1151942','ERIC'); return false;" href="https://eric.ed.gov/?q=Volunteering&pg=6&id=EJ1151942"><span>Testing Multidimensional Models of Youth Civic Engagement: Model Comparisons, Measurement Invariance, and Age Differences</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Wray-Lake, Laura; Metzger, Aaron; Syvertsen, Amy K.</p> <p>2017-01-01</p> <p>Despite recognition that youth civic engagement is multidimensional, different modeling approaches are rarely compared or tested for measurement invariance. Using a diverse sample of 2,467 elementary, middle, and high school-aged youth, we measured eight dimensions of civic engagement: social responsibility values, informal helping, political…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20438388','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20438388"><span>Ex vivo study of the home-use TriPollar RF device using an experimental human skin model.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Boisnic, Sylvie; Branchet, Marie Christine</p> <p>2010-09-01</p> <p>A wide variety of professional radio frequency (RF) aesthetic treatments for anti-aging are available aiming at skin tightening. A new home-use RF device for facial treatments has recently been developed based on TriPollar technology. To evaluate the mechanism of the new home-use device, in the process of collagen remodeling, using an ex vivo skin model. Human skin samples were collected in order to evaluate the anti-aging effect of a home-use device for facial treatments on an ex vivo human skin model. Skin tightening was evaluated by dermal histology, quantitative analysis of collagen fibers and dosage of collagen synthesis. Significant collagen remodeling following RF treatment with the device was found in the superficial and mid-deep dermis. Biochemical measurement of newly synthesized collagen showed an increase of 41% in the treated samples as compared to UV-aged control samples. The new home-use device has been demonstrated to affect significant collagen remodeling, in terms of the structural and biochemical improvement of dermal collagen on treated skin samples.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4679516','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4679516"><span>One Size Fits All? Applying Theoretical Predictions about Age and Emotional Experience to People with Functional Disabilities</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Piazza, Jennifer R.; Charles, Susan T.; Luong, Gloria; Almeida, David M.</p> <p>2015-01-01</p> <p>The current study examined whether commonly observed age differences in affective experience among community samples of healthy adults would generalize to a group of adults who live with significant functional disability. Age differences in daily affect and affective reactivity to daily stressors among a sample of participants with spinal cord injury were compared to a non-injured sample. Results revealed that patterns of affective experience varied by sample. Among non-injured adults, older age was associated with lower levels of daily negative affect (NA), higher levels of daily positive affect (PA), and less negative affective reactivity in response to daily stressors. In contrast, among participants with spinal cord injury, no age differences emerged. Findings, which support the model of Strength and Vulnerability Integration (SAVI), underscore the importance of taking life context into account when predicting age differences in affective well-being. PMID:26322552</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2005AGUFM.T32A..05S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2005AGUFM.T32A..05S"><span>Growth and Construction of Oceanic Crust at Atlantis Bank, Southwest Indian Ridge</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Schwartz, J. J.; John, B. E.; Cheadle, M. J.; Miranda, E. A.; Grimes, C. B.; Wooden, J. L.; Dick, H. J.</p> <p>2005-12-01</p> <p>Magmatic zircon is a common accessory mineral in oceanic crustal rocks including gabbro, oxide gabbro, diabase and felsic veins. Its presence in these rocks provides an exceptional opportunity to document crustal growth processes at slow-spreading mid-ocean ridges. We present nineteen Pb/U zircon SHRIMP-RG ion probe ages of lower crustal rocks collected by manned submersible, ROV, dredging and ODP drilling from a 20 x 30 km2 area of Atlantis Bank, Southwest Indian Ridge, which allow us to constrain the growth and construction of oceanic crust. Weighted average 206Pb/238U ages of these samples range from 10.7 to 13.9 Ma, with errors of 0.1-0.6 m.y. (<1 - 4%). At least 75% of these gabbros accreted within error of the predicted sea-surface magnetic age, whereas up to 25% are between 700,000 and 2.5 m.y. older. In one sample, we identified zircon with inherited cores as much as 1.5 m.y. older than their corresponding rims. There is no observable correlation between age and lithology, and the anomalously old samples are not from any specific part of Atlantis Bank; they appear to be randomly distributed amongst the non-anomalous age samples and come from various structural depths. We consider two models to explain the presence of these anomalously old rocks: i) a stochastic intrusion model whereby magma was intruded at different spatial locations within the rift valley as the plates spread apart, resulting in the entrapment of older lower crust by subsequent intrusions; and/or ii) a model in which some gabbroic bodies originally crystallized at depths of ~5-18 km below the base of the crust in a thick, cold, axial lithosphere and were subsequently uplifted along flow-lines and intruded by shallow-level magmas during the creation of Atlantis Bank. In this model, the difference in time between the Pb/U zircon crystallization age and the magnetic age is a proxy for the depth at which zircon crystallized (assuming a constant mantle upwelling rate during the construction of Atlantis Bank over ~1.3 m.y.). We prefer the latter model, although aspects of both models may apply.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_1");'>1</a></li> <li><a href="#" onclick='return showDiv("page_2");'>2</a></li> <li class="active"><span>3</span></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_3 --> <div id="page_4" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_2");'>2</a></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li class="active"><span>4</span></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="61"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/1188192','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/1188192"><span>High-Precision Plutonium Isotopic Compositions Measured on Los Alamos National Laboratory’s General’s Tanks Samples: Bearing on Model Ages, Reactor Modelling, and Sources of Material. Further Discussion of Chronometry</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Spencer, Khalil J.; Rim, Jung Ho; Porterfield, Donivan R.</p> <p>2015-06-29</p> <p>In this study, we re-analyzed late-1940’s, Manhattan Project era Plutonium-rich sludge samples recovered from the ''General’s Tanks'' located within the nation’s oldest Plutonium processing facility, Technical Area 21. These samples were initially characterized by lower accuracy, and lower precision mass spectrometric techniques. We report here information that was previously not discernable: the two tanks contain isotopically distinct Pu not only for the major (i.e., 240Pu, 239Pu) but trace ( 238Pu , 241Pu, 242Pu) isotopes. Revised isotopics slightly changed the calculated 241Am- 241Pu model ages and interpretations.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28264785','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28264785"><span>Temperament factors and dimensional, latent bifactor models of child psychopathology: Transdiagnostic and specific associations in two youth samples.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hankin, Benjamin L; Davis, Elysia Poggi; Snyder, Hannah; Young, Jami F; Glynn, Laura M; Sandman, Curt A</p> <p>2017-06-01</p> <p>Common emotional and behavioral symptoms co-occur and are associated with core temperament factors. This study investigated links between temperament and dimensional, latent psychopathology factors, including a general common psychopathology factor (p factor) and specific latent internalizing and externalizing liabilities, as captured by a bifactor model, in two independent samples of youth. Specifically, we tested the hypothesis that temperament factors of negative affectivity (NA), positive affectivity (PA), and effortful control (EC) could serve as both transdiagnostic and specific risks in relation to recent bifactor models of child psychopathology. Sample 1 included 571 youth (average age 13.6, SD =2.37, range 9.3-17.5) with both youth and parent report. Sample 2 included 554 preadolescent children (average age 7.7, SD =1.35, range =5-11 years) with parent report. Structural equation modeling showed that the latent bifactor models fit in both samples. Replicated in both samples, the p factor was associated with lower EC and higher NA (transdiagnostic risks). Several specific risks replicated in both samples after controlling for co-occurring symptoms via the p factor: internalizing was associated with higher NA and lower PA, lower EC related to externalizing problems. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/1177481','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/1177481"><span>Sixth Status Report: Testing of Aged Softwood Fiberboard Material for the 9975 Shipping Package</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Daugherty, W.</p> <p></p> <p>Samples have been prepared from several 9975 lower fiberboard subassemblies fabricated from softwood fiberboard. Physical, mechanical and thermal properties have been measured following varying periods of conditioning in each of several environments. These tests have been conducted in the same manner as previous testing on cane fiberboard samples. Overall, similar aging trends are observed for softwood and cane fiberboard samples, with a few differences. Some softwood fiberboard properties tend to degrade faster in some environments, while some cane fiberboard properties degrade faster in the two most aggressive environments. As a result, it is premature to assume both materials will agemore » at the same rates, and the preliminary aging models developed for cane fiberboard might not apply to softwood fiberboard. However, it is expected that both cane and softwood fiberboard assemblies will perform satisfactorily in conforming packages stored in a typical KAC storage environment for up to 15 years. Samples from an additional 3 softwood fiberboard assemblies have begun aging during the past year to provide information on the variability of softwood fiberboard behavior. Aging and testing of softwood fiberboard will continue and additional data will be collected to support development of an aging model specific to softwood fiberboard.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25149025','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25149025"><span>Personality and diabetes mellitus incidence in a national sample.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Cukić, Iva; Weiss, Alexander</p> <p>2014-09-01</p> <p>To test whether personality traits were prospectively associated with type 2 diabetes incidence. The sample (n=6798) was derived from the National Health and Nutrition Examination Survey Epidemiological Follow-up Study cohort. We fit four logistic regression models to test whether neuroticism, extraversion, openness to experience, or the Type A behavior pattern predicted type 2 diabetes incidence. Model 1 included sex, age, and race/ethnicity. Model 2 added personality traits, Model 3 added depressive symptoms, and Model 4 added body mass index (BMI), hypertension, and cigarette smoking status as predictors. In Model 1 age was associated with increased risk of diabetes (2% per year); being black as opposed to white was associated with a three-fold increase in risk. In Model 2 age and being black were still significant and extraversion was associated with decreased risk (17% per standard deviation [SD]). In Model 3 age, being black, and extraversion were still significant. In addition, neuroticism was associated with decreased risk (26% per SD) and depressive symptoms were associated with increased risk (28% per SD). In Model 4 age, being black, neuroticism, and depressive symptoms were still significant. BMI was associated with increased risk (14% per SD) and extraversion was no longer significant. Higher neuroticism was associated with reduced type 2 diabetes risk even after controlling for race/ethnicity, age, depressive symptoms, and BMI. Extraversion and Type A behavior were not significant after including covariates. Copyright © 2014 Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AGUFM.T11A0439G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AGUFM.T11A0439G"><span>Provenance of Late Ordovician Sandstones along the southeastern Appalachian Mountains: Implications for the Tectonic Model of the Taconic Orogeny</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Guerrero, J. C.; Herrmann, A. D.; Haynes, J.</p> <p>2017-12-01</p> <p>A provenance study of sandstones along the southeastern Appalachian Mountains has been conducted in order to test the current volcanic arc-continent collision and foreland basin formation model of the Taconic Orogeny. Samples along the southeastern Appalachians were taken from sandstone sequences deposited between 460-450 Ma. Results from these sandstones show three dominate age ranges: 465-685 Ma, 980-1300 Ma, and 1300-1500 Ma. The 980-1300 Ma and 1300-1500 Ma ages are seen throughout the study area and are compatible with previously reported ages of the Grenville Orogeny and the Rhyolite-Granite Province. The northernmost samples have a small quantity of 465-685 Ma zircons which is attributed to an accretionary wedge that formed as a result of the continent-island arc collision and acted as a physical barrier keeping sediment from depositing within the basin. The younger age signal becomes stronger to the south, as samples in Georgia and Alabama show strong concentrations of 465-685 zircons. These ages are attributed to exotic terranes (Dalhonega Terrane and Carolina Terrane) that were accreted onto Laurentia during the Taconic Orogeny and/or a possible change in subduction direction leading to a back-arc basin model for the southern Appalachian Taconic Orogeny. The results from this provenance analysis support previous studies indicating that the model for the Taconic Orogeny is a combined A-type subduction for the north and a B-type subduction model for the southern part of the orogeny.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=david+AND+wechsler&pg=4&id=EJ532028','ERIC'); return false;" href="https://eric.ed.gov/?q=david+AND+wechsler&pg=4&id=EJ532028"><span>The Two- and Three-Dimensional Models of the HK-WISC: A Confirmatory Factor Analysis.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Chan, David W.; Lin, Wen-Ying</p> <p>1996-01-01</p> <p>Confirmatory analyses on the Hong Kong Wechsler Intelligence Scale for Children (HK-WISC) provided support for composite score interpretation based on the two- and three-dimensional models across age levels. Test sample was comprised of 1,100 children, ranging in age from 5 to 15 years at all 11 age levels specified by the HK-WISC. (KW)</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=Turan&pg=3&id=EJ1025877','ERIC'); return false;" href="https://eric.ed.gov/?q=Turan&pg=3&id=EJ1025877"><span>Attitudes Towards Seeking Psychological Help among a Sample of Turkish University Students: The Roles of Rumination and Internal Working Models</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Turan, Numan; Erdur-Baker, Özgür</p> <p>2014-01-01</p> <p>The current study investigates how attitudes towards seeking psychological help relate to internal working models of attachment (self-model and other-model) and ruminative tendencies. The study includes 589 Turkish university students (278 females, 308 males and 3 unknown) by implementing a convenient sampling procedure. The average age of the…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70035416','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70035416"><span>Radiocarbon ages and age models for the past 30,000 years in Bear Lake, Utah and Idaho</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Colman, Steven M.; Rosenbaum, J.G.; Kaufman, D.S.; Dean, W.E.; McGeehin, J.P.</p> <p>2009-01-01</p> <p>Radiocarbon analyses of pollen, ostracodes, and total organic carbon (TOC) provide a reliable chronology for the sediments deposited in Bear Lake over the past 30,000 years. The differences in apparent age between TOC, pollen, and carbonate fractions are consistent and in accord with the origins of these fractions. Comparisons among different fractions indicate that pollen sample ages are the most reliable, at least for the past 15,000 years. The post-glacial radiocarbon data also agree with ages independently estimated from aspartic acid racemization in ostracodes. Ages in the red, siliclastic unit, inferred to be of last glacial age, appear to be several thousand years too old, probably because of a high proportion of reworked, refractory organic carbon in the pollen samples. Age-depth models for five piston cores and the Bear Lake drill core (BL00-1) were constructed by using two methods: quadratic equations and smooth cubic-splinefits. The two types of age models differ only in detail for individual cores, and each approach has its own advantages. Specific lithological horizons were dated in several cores and correlated among them, producing robust average ages for these horizons. The age of the correlated horizons in the red, siliclastic unit can be estimated from the age model for BL00-1, which is controlled by ages above and below the red, siliclastic unit. These ages were then transferred to the correlative horizons in the shorter piston cores, providing control for the sections of the age models in those cores in the red, siliclastic unit. These age models are the backbone for reconstructions of past environmental conditions in Bear Lake. In general, sedimentation rates in Bear Lake have been quite uniform, mostly between 0.3 and 0.8 mm yr-1 in the Holocene, and close to 0.5 mm yr-1 for the longer sedimentary record in the drill core from the deepest part of the lake. Copyright ?? 2009 The Geological Society of America.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25399049','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25399049"><span>Age-related DNA methylation changes for forensic age-prediction.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Yi, Shao Hua; Jia, Yun Shu; Mei, Kun; Yang, Rong Zhi; Huang, Dai Xin</p> <p>2015-03-01</p> <p>There is no available method of age-prediction for biological samples. The accumulating evidences indicate that DNA methylation patterns change with age. Aging resembles a developmentally regulated process that is tightly controlled by specific epigenetic modifications and age-associated methylation changes exist in human genome. In this study, three age-related methylation fragments were isolated and identified in blood of 40 donors. Age-related methylation changes with each fragment was validated and replicated in a general population sample of 65 donors over a wide age range (11-72 years). Methylation of these fragments is linearly correlated with age over a range of six decades (r = 0.80-0.88). Using average methylation of CpG sites of three fragments, a regression model that explained 95 % of the variance in age was built and is able to predict an individual's age with great accuracy (R (2 )= 0.93). The predicted value is highly correlated with the observed age in the sample (r = 0.96) and has great accuracy of average 4 years difference between predicted age and true age. This study implicates that DNA methylation can be an available biological marker of age-prediction. Further measurement of relevant markers in the genome could be a tool in routine screening to predict age of forensic biological samples.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26056714','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26056714"><span>Novel ageing-biomarker discovery using data-intensive technologies.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Griffiths, H R; Augustyniak, E M; Bennett, S J; Debacq-Chainiaux, F; Dunston, C R; Kristensen, P; Melchjorsen, C J; Navarrete, Santos A; Simm, A; Toussaint, O</p> <p>2015-11-01</p> <p>Ageing is accompanied by many visible characteristics. Other biological and physiological markers are also well-described e.g. loss of circulating sex hormones and increased inflammatory cytokines. Biomarkers for healthy ageing studies are presently predicated on existing knowledge of ageing traits. The increasing availability of data-intensive methods enables deep-analysis of biological samples for novel biomarkers. We have adopted two discrete approaches in MARK-AGE Work Package 7 for biomarker discovery; (1) microarray analyses and/or proteomics in cell systems e.g. endothelial progenitor cells or T cell ageing including a stress model; and (2) investigation of cellular material and plasma directly from tightly-defined proband subsets of different ages using proteomic, transcriptomic and miR array. The first approach provided longitudinal insight into endothelial progenitor and T cell ageing. This review describes the strategy and use of hypothesis-free, data-intensive approaches to explore cellular proteins, miR, mRNA and plasma proteins as healthy ageing biomarkers, using ageing models and directly within samples from adults of different ages. It considers the challenges associated with integrating multiple models and pilot studies as rational biomarkers for a large cohort study. From this approach, a number of high-throughput methods were developed to evaluate novel, putative biomarkers of ageing in the MARK-AGE cohort. Crown Copyright © 2015. Published by Elsevier Ireland Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21046536','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21046536"><span>[Psychiatry of the life span?--relevance of age in psychiatric research].</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sikorski, Claudia; Motzek, Tom</p> <p>2010-11-01</p> <p>The aim of this study was to determine to what extent studies published in two German journals took the age of their sample into consideration. All publications of the two journals were viewed. Only empirical research papers were included. It was then assessed whether they included information on age of the sample and, if that was the case, the studies were further categorized as only giving descriptive sample information, reporting age-specific results of dependent variables or using age as a predictor in regression analyses. Furthermore, the age range covered was assessed. 88 % of all studies included information on age. Of those, about half only provided descriptive information on the age of the study sample, while more than one third used the age variable as a predictor in multivariate models. Few studies reported age-specific outcomes. Main focus of research was on adult populations aged 18 to 65. Only few studies concentrated on children and adolescents. In light of demographic change and age specificity of psychological disorders, it will be necessary to further differentiate and report age-specific results of psychiatric research. A change in what is considered normative aging and developmental tasks for certain age groups calls for further research in those age groups. © Georg Thieme Verlag KG Stuttgart · New York.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1249132-review-lunar-chronology-revealing-preponderance-ga-ages','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1249132-review-lunar-chronology-revealing-preponderance-ga-ages"><span>A review of lunar chronology revealing a preponderance of 4.34-4.37 Ga ages</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a></p> <p>Borg, Lars E.; Gaffney, Amy M.; Shearer, Charles K.</p> <p>2014-11-24</p> <p>In this study, data obtained from Sm-Nd and Rb-Sr isotopic measurements of lunar highlands’ samples are renormalized to common standard values and then used to define ages with a common isochron regression algorithm. The reliability of these ages is evaluated using five criteria that include whether: (1) the ages are defined by multiple isotopic systems, (2) the data demonstrate limited scatter outside uncertainty, (3) initial isotopic compositions are consistent with the petrogenesis of the samples, (4) the ages are defined by an isotopic system that is resistant to disturbance by impact metamorphism, and (5) the rare-earth element abundances determined bymore » isotope dilution of bulk of mineral fractions match those measured by in situ analyses. From this analysis, it is apparent that the oldest highlands’ rock ages are some of the least reliable, and that there is little support for crustal ages older than ~4.40 Ga. A model age for ur-KREEP formation calculated using the most reliable Mg-suite Sm-Nd isotopic systematics, in conjunction with Sm-Nd analyses of KREEP basalts, is 4389 ± 45 Ma. This age is a good match to the Lu-Hf model age of 4353 ± 37 Ma determined using a subset of this sample suite, the average model age of 4353 ± 25 Ma determined on mare basalts with the 146Sm- 142Nd isotopic system, with a peak in Pb-Pb ages observed in lunar zircons of ~4340 ± 20 Ma, and the oldest terrestrial zircon age of 4374 ± 6 Ma. The preponderance of ages between 4.34 and 4.37 Ga reflect either primordial solidification of a lunar magma ocean or a widespread secondary magmatic event on the lunar nearside. The first scenario is not consistent with the oldest ages reported for lunar zircons, whereas the second scenario does not account for concordance between ages of crustal rocks and mantle reservoirs.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26165657','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26165657"><span>Application of third molar development and eruption models in estimating dental age in Malay sub-adults.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Mohd Yusof, Mohd Yusmiaidil Putera; Cauwels, Rita; Deschepper, Ellen; Martens, Luc</p> <p>2015-08-01</p> <p>The third molar development (TMD) has been widely utilized as one of the radiographic method for dental age estimation. By using the same radiograph of the same individual, third molar eruption (TME) information can be incorporated to the TMD regression model. This study aims to evaluate the performance of dental age estimation in individual method models and the combined model (TMD and TME) based on the classic regressions of multiple linear and principal component analysis. A sample of 705 digital panoramic radiographs of Malay sub-adults aged between 14.1 and 23.8 years was collected. The techniques described by Gleiser and Hunt (modified by Kohler) and Olze were employed to stage the TMD and TME, respectively. The data was divided to develop three respective models based on the two regressions of multiple linear and principal component analysis. The trained models were then validated on the test sample and the accuracy of age prediction was compared between each model. The coefficient of determination (R²) and root mean square error (RMSE) were calculated. In both genders, adjusted R² yielded an increment in the linear regressions of combined model as compared to the individual models. The overall decrease in RMSE was detected in combined model as compared to TMD (0.03-0.06) and TME (0.2-0.8). In principal component regression, low value of adjusted R(2) and high RMSE except in male were exhibited in combined model. Dental age estimation is better predicted using combined model in multiple linear regression models. Copyright © 2015 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28242578','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28242578"><span>The role of perceived discrimination on active aging.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Fernandez-Ballesteros, Rocio; Olmos, Ricardo; Santacreu, Marta; Bustillos, Antonio; Molina, Maria Angeles</p> <p>2017-07-01</p> <p>Among older adults, perceived age discrimination is highly associated with unhealthy outcomes and dissatisfaction. Active aging is a multidimensional concept described by a set of characteristics, particularly health, positive mood and control; most importantly, active aging is currently at the core of public policies. The aim of the present study was to test to what extent perceived discrimination influences active aging. Methods A total of 2005 older adults in three representative samples from regions of Germany, Mexico and Spain participated; they were tested on active aging and perceived discrimination. First, active aging was defined as high reported health, life satisfaction and self-perception of aging. Second, authors introduced the assumption that, in the total sample, structural equation modelling would confirm the hypothesis of a direct negative link between perceived age discrimination and active aging. Finally, multiple group comparison performed through structural equation modelling also provided support for the negative association between perceived discrimination and active aging proposed. In spite of the differences found among the three countries in both active aging variables and age discrimination perception, multiple group comparison indicates that regardless of the culture, perceived discrimination is a negative predictor of active aging. Copyright © 2017 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70187204','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70187204"><span>Accurate aging of juvenile salmonids using fork lengths</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Sethi, Suresh; Gerken, Jonathon; Ashline, Joshua</p> <p>2017-01-01</p> <p>Juvenile salmon life history strategies, survival, and habitat interactions may vary by age cohort. However, aging individual juvenile fish using scale reading is time consuming and can be error prone. Fork length data are routinely measured while sampling juvenile salmonids. We explore the performance of aging juvenile fish based solely on fork length data, using finite Gaussian mixture models to describe multimodal size distributions and estimate optimal age-discriminating length thresholds. Fork length-based ages are compared against a validation set of juvenile coho salmon, Oncorynchus kisutch, aged by scales. Results for juvenile coho salmon indicate greater than 95% accuracy can be achieved by aging fish using length thresholds estimated from mixture models. Highest accuracy is achieved when aged fish are compared to length thresholds generated from samples from the same drainage, time of year, and habitat type (lentic versus lotic), although relatively high aging accuracy can still be achieved when thresholds are extrapolated to fish from populations in different years or drainages. Fork length-based aging thresholds are applicable for taxa for which multiple age cohorts coexist sympatrically. Where applicable, the method of aging individual fish is relatively quick to implement and can avoid ager interpretation bias common in scale-based aging.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21553306','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21553306"><span>Assessment of dietary restraint: psychometric properties of the revised restraint scale in Hong Kong adolescents.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Mak, Kwok-Kei; Lai, Ching-Man</p> <p>2012-06-01</p> <p>The psychometric properties of the Revised Restraint Scale (RRS) have been well established in western populations but not in Chinese adolescents. This study investigated the psychometric properties of RRS and its validity in different subgroups for Hong Kong Chinese adolescents. In 2007, 909 Hong Kong students aged 12 to 18 years (55.3% boys) completed a questionnaire including demographic items, RRS, Eating Attitudes Test (EAT-26), and Motivation for Eating Scale (MFES)-physical. Moreover, subjects' height and weight were measured. To examine the factor structure of RRS, the whole sample was randomly split into two groups (sample 1: N=454 and sample 2: N=455) for exploratory factor analysis (EFA) and confirmatory factor analysis (CFA), respectively. Convergent and discriminant validity of RRS were investigated by correlating the RRS with EAT-26 and MFES-physical. Multigroup CFA was conducted to test the three-factor model of RRS in different sex, age, and weight status subgroups. Results of EFA for sample 1 revealed three strongly correlated factors for the RRS construct, and were supported by the CFA results in sample 2. Multigroup CFA further suggested that the three-factor model of RRS was stable across sex, age, and weight status subgroups. A new three-factor model is proposed for Hong Kong adolescents in this study. In general, RRS is a reliable and valid measure of restrained eating for adolescents, regardless of sex, age, and weight status.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3350460','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3350460"><span>Factor structure and psychometric properties of the trier inventory for chronic stress (TICS) in a representative german sample</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2012-01-01</p> <p>Background Chronic stress results from an imbalance of personal traits, resources and the demands placed upon an individual by social and occupational situations. This chronic stress can be measured using the Trier Inventory for Chronic Stress (TICS). Aims of the present study are to test the factorial structure of the TICS, report its psychometric properties, and evaluate the influence of gender and age on chronic stress. Methods The TICS was answered by N = 2,339 healthy participants aged 14 to 99. The sample was selected by random-route sampling. Exploratory factor analyses with Oblimin-rotated Principal Axis extraction were calculated. Confirmatory factor analyses applying Robust Maximum Likelihood estimations (MLM) tested model fit and configural invariance as well as the measurement invariance for gender and age. Reliability estimations and effect sizes are reported. Results In the exploratory factor analyses, both a two-factor and a nine-factor model emerged. Confirmatory factor analyses resulted in acceptable model fit (RMSEA), with model comparison fit statistics corroborating the superiority of the nine-factor model. Most factors were moderately to highly intercorrelated. Reliabilities were good to very good. Measurement invariance tests gave evidence for differential effects of gender and age on the factor structure. Furthermore, women and younger individuals, especially those aged 35 to 44, tended to report more chronic stress than men and older individuals. Conclusions The proposed nine-factor structure could be factorially validated, results in good scale reliability, and heuristically can be grouped by two higher-order factors: "High Demands" and "Lack of Satisfaction". Age and gender represent differentiable and meaningful contributors to the perception of chronic stress. PMID:22463771</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012AGUFM.P42A..06B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012AGUFM.P42A..06B"><span>Evaluation of Ages in the Lunar Highlands with Implications for the Evolution of the Moon</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Borg, L. E.; Gaffney, A. M.; Carlson, R. W.</p> <p>2012-12-01</p> <p>The lunar highlands are composed of rocks from the ferroan anorthosite (FAN) and Mg-suites. These samples have been extensively studied because they record most of the major events associated with the formation and evolution of the Earth's Moon. Despite their potential to constrain the timing of these events, chronologic investigations are often ambiguous; in most cases because absolute ages and/or initial isotopic compositions are inconsistent with stratigraphic and petrologic relationships of various rock suites inferred from mineralogical and geochemical studies. The problem is exacerbated by the fact that most samples are difficult to date due to their small size and nearly monomineralic nature, as well as isotopic disturbances associated with impacts. Here several criteria are used to assess the reliability of lunar ages, including: (1) concordance between multiple chronometers, (2) linearity of individual isochrons, (3) resistance of the chronometers to disruption by impact or contamination, (4) consistency between initial isotopic compositions and the petrogenisis of samples, and (5) reasonableness of the elemental concentrations of mineral fractions. If only those samples that meet 4 out of 5 of these criteria are used to constrain lunar chronology many of the apparent conflicts between chronometry and petrology disappear. For example, this analysis demonstrates that the most ancient ages reported for lunar samples are some of the least reliable. The oldest ages determined on both FAN and Mg-suite highland rocks with confidence are in fact ~4.35 Ga. This age is concordant with 142Nd mare source formation ages and a peak in zircon ages, suggesting it represents a major event at ~4.35 Ga. In contrast, several apparently reliable KREEP model ages are older at ~4.48 Ga. If these older model ages are correct, they may represent the solidification age of the Moon, whereas the 4.35 Ga event could reflect secondary magmatism and cumulate re-equilibration associated with density overturn of primordial magma ocean cumulates.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23995050','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23995050"><span>The impact of age on lamotrigine and oxcarbazepine kinetics: a historical cohort study.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Wegner, Ilse; Wilhelm, Abraham J; Sander, Josemir W; Lindhout, Dick</p> <p>2013-10-01</p> <p>Age as well as estrogen levels may have an impact on the pharmacokinetics of lamotrigine (LTG) and monohydroxycarbazepine (MHD), the active metabolite of oxcarbazepine (OXC). To assess the effects of age and menopause, we evaluated retrospectively a therapeutic drug-monitoring database. Samples from 507 women and 302 men taking LTG and 464 women and 319 men taking OXC were used to develop a population pharmacokinetic model. Data were analyzed using NONMEM software and were compared with a population pharmacokinetic model based on samples of 1705 women and 1771 men taking carbamazepine (CBZ). Age was a significant factor contributing to pharmacokinetic variability in individuals using LTG, OXC, and CBZ with increasing clearance as a function of bioavailability (Cl/F) over age 18, a maximum Cl/F at 33years (CBZ) and 36 years (LTG and OXC), and a gradual decrease of Cl/F towards older age. We found no effect of perimenopausal age range on LTG and MHD clearance. © 2013.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24607743','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24607743"><span>Phylogenetic analysis accounting for age-dependent death and sampling with applications to epidemics.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lambert, Amaury; Alexander, Helen K; Stadler, Tanja</p> <p>2014-07-07</p> <p>The reconstruction of phylogenetic trees based on viral genetic sequence data sequentially sampled from an epidemic provides estimates of the past transmission dynamics, by fitting epidemiological models to these trees. To our knowledge, none of the epidemiological models currently used in phylogenetics can account for recovery rates and sampling rates dependent on the time elapsed since transmission, i.e. age of infection. Here we introduce an epidemiological model where infectives leave the epidemic, by either recovery or sampling, after some random time which may follow an arbitrary distribution. We derive an expression for the likelihood of the phylogenetic tree of sampled infectives under our general epidemiological model. The analytic concept developed in this paper will facilitate inference of past epidemiological dynamics and provide an analytical framework for performing very efficient simulations of phylogenetic trees under our model. The main idea of our analytic study is that the non-Markovian epidemiological model giving rise to phylogenetic trees growing vertically as time goes by can be represented by a Markovian "coalescent point process" growing horizontally by the sequential addition of pairs of coalescence and sampling times. As examples, we discuss two special cases of our general model, described in terms of influenza and HIV epidemics. Though phrased in epidemiological terms, our framework can also be used for instance to fit macroevolutionary models to phylogenies of extant and extinct species, accounting for general species lifetime distributions. Copyright © 2014 Elsevier Ltd. All rights reserved.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_2");'>2</a></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li class="active"><span>4</span></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_4 --> <div id="page_5" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li class="active"><span>5</span></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="81"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=batteries&pg=3&id=EJ1165818','ERIC'); return false;" href="https://eric.ed.gov/?q=batteries&pg=3&id=EJ1165818"><span>Investigating the Theoretical Structure of the DAS-II Core Battery at School Age Using Bayesian Structural Equation Modeling</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Dombrowski, Stefan C.; Golay, Philippe; McGill, Ryan J.; Canivez, Gary L.</p> <p>2018-01-01</p> <p>Bayesian structural equation modeling (BSEM) was used to investigate the latent structure of the Differential Ability Scales-Second Edition core battery using the standardization sample normative data for ages 7-17. Results revealed plausibility of a three-factor model, consistent with publisher theory, expressed as either a higher-order (HO) or a…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21046208','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21046208"><span>Pharmacokinetic design optimization in children and estimation of maturation parameters: example of cytochrome P450 3A4.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bouillon-Pichault, Marion; Jullien, Vincent; Bazzoli, Caroline; Pons, Gérard; Tod, Michel</p> <p>2011-02-01</p> <p>The aim of this work was to determine whether optimizing the study design in terms of ages and sampling times for a drug eliminated solely via cytochrome P450 3A4 (CYP3A4) would allow us to accurately estimate the pharmacokinetic parameters throughout the entire childhood timespan, while taking into account age- and weight-related changes. A linear monocompartmental model with first-order absorption was used successively with three different residual error models and previously published pharmacokinetic parameters ("true values"). The optimal ages were established by D-optimization using the CYP3A4 maturation function to create "optimized demographic databases." The post-dose times for each previously selected age were determined by D-optimization using the pharmacokinetic model to create "optimized sparse sampling databases." We simulated concentrations by applying the population pharmacokinetic model to the optimized sparse sampling databases to create optimized concentration databases. The latter were modeled to estimate population pharmacokinetic parameters. We then compared true and estimated parameter values. The established optimal design comprised four age ranges: 0.008 years old (i.e., around 3 days), 0.192 years old (i.e., around 2 months), 1.325 years old, and adults, with the same number of subjects per group and three or four samples per subject, in accordance with the error model. The population pharmacokinetic parameters that we estimated with this design were precise and unbiased (root mean square error [RMSE] and mean prediction error [MPE] less than 11% for clearance and distribution volume and less than 18% for k(a)), whereas the maturation parameters were unbiased but less precise (MPE < 6% and RMSE < 37%). Based on our results, taking growth and maturation into account a priori in a pediatric pharmacokinetic study is theoretically feasible. However, it requires that very early ages be included in studies, which may present an obstacle to the use of this approach. First-pass effects, alternative elimination routes, and combined elimination pathways should also be investigated.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19342199','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19342199"><span>Validation of the Schizotypal Personality Questionnaire-Brief Form in adolescents.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Fonseca-Pedrero, Eduardo; Paíno-Piñeiro, Mercedes; Lemos-Giráldez, Serafín; Villazón-García, Ursula; Muñiz, José</p> <p>2009-06-01</p> <p>The main objective of the study was to validate the Schizotypal Personality Questionnaire-Brief (SPQ-B) in a sample of non-clinical adolescents. In addition, the schizotypal personality structure and differences in the dimensions of schizotypy according to gender and age are analyzed. The sample comprises 1683 students, 818 males (48.6%), with a mean age of 15.9 years (SD=1.2). The results showed that the SPQ-B had adequate psychometric properties. Internal consistency of the subscales and total score ranged from 0.61 to 0.81. Confirmatory factor analyses indicated that the three-factor model (positive, negative, and disorganized) and the four-factor model (positive, paranoid, negative, and disorganized) fit reasonably well in comparison to the remaining models. With regard to gender and age, statistically significant differences were found due to age but not to gender. In line with previous literature, the results confirmed the multi-factor structure of the schizotypal personality in non-clinical adolescent populations. Future studies could use the SPQ-B as a screening self-report of rapid and efficient application for the detection of adolescents vulnerable to the development of schizophrenia-spectrum disorders in the general population, in genetically high-risk samples and in clinical studies.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24004758','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24004758"><span>Work Ability: using structural equation modeling to assess the effects of aging, health and work on the population of Brazilian municipal employees.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Alcântara, Marcus A; Sampaio, Rosana F; Assunção, Ada Ávila; Silva, Fabiana C Martins</p> <p>2014-01-01</p> <p>The Work Ability Model has a holistic structure that incorporates individual characteristics, work-related factors and life outside of work. The model has been explored in the context of Finland but still needs to be applied in other countries. The aim of this study was to examine the relationships between age, health, work and work ability in a sample of Brazilian municipal employees. A sample of 5,646 workers answered a web-survey questionnaire that collected information about socio-demographics, health, work characteristics and work ability. Structural equation modeling (SEM) was used to examine the simultaneous relationships between the variables that comprise the Work Ability Model. The sample was predominantly female (68.0%), between 30 and 49 years old (60.0%) and highly educated (66.0%). SEM produced good fit indexes that supported the Work Ability Model. Age was positively related to work ability and negatively related to health. Health and work characteristics positively influenced work ability. The results produced additional support for the conceptualization of work ability as a complex and dynamic phenomenon: a system composed of an individual and various elements of his/her work interact in time and space in a nonlinear way.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29048307','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29048307"><span>Assessing aging stereotypes: Personal stereotypes, self-stereotypes and self-perception of aging.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Fernández-Ballesteros, Rocío; Olmos, Ricardo; Santacreu, Marta; Bustillos, Antonio; Schettini, Rocío; Huici, Carmen; Rivera, José M</p> <p>2017-11-01</p> <p>There is a broad semantic network of aging stereotypes; where different concepts and their measurement are confused: personal stereotypes, self-stereotypes and self-perception of aging. First, we analyze the translated version of the Image of Aging Scale (IAS) measurement model through exploratory and confirmatory factor analysis, with two representative sub-samples of the Spanish population aged over eighteen (N = 1,105) and in a sample of gerontologists and geriatricians (N = 325). Second, in an effort to disentangle the theoretical relationships between personal stereotypes, self-stereotypes and self-perception of aging, both the IAS (with different instructions) and Lawton’s 5-item scale were administered to a representative sample of Spanish people over 50. Our results indicate that the Spanish version of the IAS has a similar psychometric structure to that proposed by the authors. Furthermore, the factorial structure (equal form and metric invariance) is replicated in both samples, but latent means and factor correlations were higher in the professional group. We discuss Levy’s theoretical assumptions about personal-stereotypes and the self-stereotype measured with IAS and their relationship to self-perception of ageing.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2004cbhg.sympE..55S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2004cbhg.sympE..55S"><span>The Frequency of Circumnuclear Starbursts in Seyfert Galaxies --- Testing the Starburst-AGN Connection</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Schinnerer, E.; Colbert, E.; Armus, L.; Scoville, N. Z.; Heckman, T. M.</p> <p></p> <p>We obtained sub-arcsecond medium resolution near-infrared spectra of a sample of nearby bright Seyfert galaxies (8 Seyfert 1s, 11 Seyfert 2s) using the KeckII telescope. The stellar absorption lines present in the spectra were used in conjunction with population synthesis models to determine the age of the circumnuclear stellar population. Initial analysis of a sub-sample of the Seyfert galaxies has provided no evidence for a connection between the age of the circumnuclear stellar population and the Seyfert type. The derived ages for the circumnuclear stellar population are in the range of 10 Myr to < 0.5 Gyr assuming an instantaneous starburst (using the STARBURST99 models).</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=impacts+AND+delinquency&id=EJ933776','ERIC'); return false;" href="https://eric.ed.gov/?q=impacts+AND+delinquency&id=EJ933776"><span>Depression and Delinquency Covariation in an Accelerated Longitudinal Sample of Adolescents</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Kofler, Michael J.; McCart, Michael R.; Zajac, Kristyn; Ruggiero, Kenneth J.; Saunders, Benjamin E.; Kilpatrick, Dean G.</p> <p>2011-01-01</p> <p>Objectives: The current study tested opposing predictions stemming from the failure and acting out theories of depression-delinquency covariation. Method: Participants included a nationwide longitudinal sample of adolescents (N = 3,604) ages 12 to 17. Competing models were tested with cohort-sequential latent growth curve modeling to determine…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70030820','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70030820"><span>Age-structured mark-recapture analysis: A virtual-population-analysis-based model for analyzing age-structured capture-recapture data</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Coggins, L.G.; Pine, William E.; Walters, C.J.; Martell, S.J.D.</p> <p>2006-01-01</p> <p>We present a new model to estimate capture probabilities, survival, abundance, and recruitment using traditional Jolly-Seber capture-recapture methods within a standard fisheries virtual population analysis framework. This approach compares the numbers of marked and unmarked fish at age captured in each year of sampling with predictions based on estimated vulnerabilities and abundance in a likelihood function. Recruitment to the earliest age at which fish can be tagged is estimated by using a virtual population analysis method to back-calculate the expected numbers of unmarked fish at risk of capture. By using information from both marked and unmarked animals in a standard fisheries age structure framework, this approach is well suited to the sparse data situations common in long-term capture-recapture programs with variable sampling effort. ?? Copyright by the American Fisheries Society 2006.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2493384','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2493384"><span>Cross-sectional study of height and weight in the population of Andalusia from age 3 to adulthood</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>López-Siguero, Juan Pedro; García, Juan Manuel Fernández; Castillo, Juan de Dios Luna; Molina, Jose Antonio Moreno; Cosano, Carlos Ruiz; Ortiz, Antonio Jurado</p> <p>2008-01-01</p> <p>Background and objectives In Andalusia there were no studies including a representative sample of children and adolescent population assessing growth and weight increase. Our objectives were to develop reference standards for weight, height and BMI for the Andalusian pediatric population, from 3 to 18 years of age for both genders, and to identify the final adult height in Andalusia. Subjects and methods Two samples were collected. The first included individuals from 3 to 18 years of age (3592 girls and 3605 boys). They were stratified according type of study center, size of population of origin, age (32 categories of 0.5 years) and gender, using cluster sampling. Subjects from >18 to 23 years of age (947 women and 921 men) were sampled in 6 non-university educational centers and several university centers in Granada. Exclusion criteria included sons of non-Spanish mother or father, and individuals with chronic conditions and/or therapies affecting growth. Two trained fellows collected the data through February to December 2004, for the first sample, and through January to May 2005, for the second. Reference curves were adjusted using Cole's LMS method, and the quality of the adjustment was assessed using the tests proposed by Royston. In addition, a sensitivity analysis was applied to the final models obtained. Results Data for 9065 cases (4539 women and 4526 men) were obtained; 79.39% (n = 7197) in the up to 18 years of age group. In the first sampling only 0.07% (3 girls and 2 boys) refused to participate in the study. In addition, 327 students (4.5%) were absent when sampling was done. We present mean and standard deviation fort height, weight and BMI at 0.5 years intervals, from 3 to 23 years of age, for both genders. After adjustment with the different models, percentiles for height, weight (percentiles 3, 5, 10, 25, 50, 75, 90, 95, and 97) and BMI (percentiles 3, 5, 50, 85, 95, and 97) are presented for both genders. Conclusion This is the first study in Andalusia with a representative sample from the child-juvenile population to investigate weight, height and BMI in subjects from 3 to 23 years of age. The great variability observed in the values from sample of 18 to 23 years of age individuals, ensures the inclusion of extreme values, although random sampling was not used. There still is a lack of standard reference values for the Andalusian population younger done 3 years of age. PMID:18673524</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011PhDT.......180A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011PhDT.......180A"><span>Etude de l'effet du vieillissement sur les proprietes d'un tissu en melange KevlarRTM-PBI utilise dans le revetement exterieur des habits de protection contre le feu</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Arrieta, Carlos</p> <p></p> <p>The aim of this work is to study and model the effect of three aging factors, temperature, humidity and light radiation, on the properties of a fabric made of a blend of KevlarRTM and PBI fibers frequently used to manufacture fire-protective garments. Accelarated-aging treatments carried out at carefully chosen conditions for the three factors resulted in a sizeable loss of mechanical performance. The breaking force of both the fabric and the yarns extracted from it decreases to less than 50% after one month of continuous exposure. X-ray diffraction (XRD) tests performed on thermally-aged samples indicated an increase of the crystallinity of the fabric, whereas the disappearance of Raman spectral lines suggested instead a reduction of the crystallinity following thermal aging. To explain these seemingly contradictory results, a hypothesis was introduced, stating that two different processes occurred simultaneously during thermal aging. The first one, an increase of size of the crystallites in the direction of the fibers' axis, accounted for the increase in crystallinity observed in XRD tests. The second one, an increase in the gap separating lamellar crystallites that causes a non-measurable reduction of the crystallinity of the sample, was highlighted by the Raman analyses. The results of the dielectric spectroscopy analyses carried out on thermally-aged samples confirmed the XRD results showing a significant change in the Kevlar's morphology during thermal aging. Despite the important decrease of the breaking force that ensued thermal aging, no evidence of a chemical structure modification of KevlarRTM was found. On the other hand, differential thermal analyses conducted on thermally aged fabric samples indicated a reduction of the glass transition temperature of the other component of the blend, namely the PBI, a fact that suggests a decrease of molecular weight after thermal aging. Infrared spectroscopy analyses performed on samples exposed to high humidity levels showed the development of a new absorbing band in the spectrum of aged KevlarRTM yarns. This band was ascribed to the formation of carboxylic acid groups. Based on these results, the humidity aging mechanism was inferred. This mechanism corresponds to the hydrolysis of the amide bond of KevlarRTM catalyzed by an acid. The progress of the hydrolysis reaction was modeled mathematically using the evolution of the concentration of carboxylic acid groups. The mechanism of light radiation aging was also determined from infrared spectroscopy analyses as the absorbing band attributed to the carboxylic acid groups was once again observed. In the case of light radiation, the degradation mechanism corresponds to a photo-oxidation reaction initiated by the photolysis of the amide bond of KevlarRTM. The accumulation of Photo-Fries products on the surface of yarns is believed to slow down of the oxidation reaction, as indicated by the overlapping of breaking force vs. aging time curves for the light-radiation aged samples. Expressions based on the Arrhenius law were used to characterize both the thermal and hydrolytic aging, whereas an expression taking into account the irradiance as well as the temperature was used to model the light radiation aging. The global damage produced by the joint action of the three aging factors was modeled after Palmgren-Miner's linear cumulative damage theory.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22284838','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22284838"><span>Age-related changes in the auditory brainstem response.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Konrad-Martin, Dawn; Dille, Marilyn F; McMillan, Garnett; Griest, Susan; McDermott, Daniel; Fausti, Stephen A; Austin, Donald F</p> <p>2012-01-01</p> <p>This cross-sectional study had two goals: (1) Identify and quantify the effects of aging on the auditory brainstem response (ABR); (2) Describe how click rate and hearing impairment modify effects of aging. RESEARCH DESIGN AND ANALYSIS: ABR measures were obtained from 131 predominately male Veteran participants aged 26 to 71 yr. Metrics analyzed include amplitude and latency for waves I, III, and V, and the I-V interpeak latency interval (IPI) at three repetition rates (11, 51, and 71 clicks/sec) using both polarities. In order to avoid confounding from missing data due to hearing impairment, participants had hearing thresholds <40 dB HL at 2 kHz and 70 dB HL at 4 kHz in at least one ear. Additionally, the median 2, 3, and 4 kHz pure tone threshold average (PTA2,3,4) for the sample, ∼17 dB HL, was used to delineate subgroups of better and worse hearing ears, and only the better hearing sample was modeled statistically. We modeled ABR responses using age, repetition rate, and PTA2,3,4 as covariates. Random effects were used to model correlation between the two ears of a subject and across repetition rates. Inferences regarding effects of aging on ABR measures at each rate were derived from the fitted model. Results were compared to data from subjects with poorer hearing. Aging substantially diminished amplitudes of all of the principal ABR peaks, largely independent of any threshold differences within the group. For waves I and III, age-related amplitude decrements were greatest at a low (11/sec) click rate. At the 11/sec rate, the model-based mean wave III amplitude was significantly smaller in older compared with younger subjects even after adjusting for wave I amplitude. Aging also increased ABR peak latencies, with significant shifts limited to early waves. The I-V IPI did not change with age. For both younger and older subjects, increasing click presentation rate significantly decreased amplitudes of early peaks and prolonged latencies of later peaks, resulting in increased IPIs. Advanced age did not enhance effects of rate. Instead, the rate effect on wave I and III amplitudes was attenuated for the older subjects due to reduced peak amplitudes at lower click rates. Compared with model predictions from the sample of better hearing subjects, mean ABR amplitudes were diminished in the group with poorer hearing, and wave V latencies were prolonged. In a sample of veterans, aging substantially reduced amplitudes of all principal ABR peaks, with significant latency shifts limited to waves I and III. Aging did not influence the I-V IPI even at high click rates, suggesting that the observed absolute latency changes associated with aging can be attributed to changes in auditory nerve input. In contrast, ABR amplitude changes with age are not adequately explained by changes in wave I. Results suggest that aging reduces the numbers and/or synchrony of contributing auditory nerve units. Results also support the concept that aging reduces the numbers, though perhaps not the synchrony, of central ABR generators. American Academy of Audiology.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=family+AND+adoptive+AND+birth+AND+parents&pg=4&id=EJ314263','ERIC'); return false;" href="https://eric.ed.gov/?q=family+AND+adoptive+AND+birth+AND+parents&pg=4&id=EJ314263"><span>Intellectual Development within Transracial Adoptive Families: Retesting the Confluence Model.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Berbaum, Michael L.; Moreland, Richard L.</p> <p>1985-01-01</p> <p>Estimates confluence model of intellectual development for a within-family sample of 321 children from 101 transracial adoptive families. Mental ages of children and their parents and birth or adoption intervals were used in a nonlinear least-squares estimation procedure to obtain children's predicted mental ages. Results suggest efficiency of the…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70029812','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70029812"><span>Circum-Arctic petroleum systems identified using decision-tree chemometrics</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Peters, K.E.; Ramos, L.S.; Zumberge, J.E.; Valin, Z.C.; Scotese, C.R.; Gautier, D.L.</p> <p>2007-01-01</p> <p>Source- and age-related biomarker and isotopic data were measured for more than 1000 crude oil samples from wells and seeps collected above approximately 55??N latitude. A unique, multitiered chemometric (multivariate statistical) decision tree was created that allowed automated classification of 31 genetically distinct circumArctic oil families based on a training set of 622 oil samples. The method, which we call decision-tree chemometrics, uses principal components analysis and multiple tiers of K-nearest neighbor and SIMCA (soft independent modeling of class analogy) models to classify and assign confidence limits for newly acquired oil samples and source rock extracts. Geochemical data for each oil sample were also used to infer the age, lithology, organic matter input, depositional environment, and identity of its source rock. These results demonstrate the value of large petroleum databases where all samples were analyzed using the same procedures and instrumentation. Copyright ?? 2007. The American Association of Petroleum Geologists. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29116006','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29116006"><span>Analysis of near infrared spectra for age-grading of wild populations of Anopheles gambiae.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Krajacich, Benjamin J; Meyers, Jacob I; Alout, Haoues; Dabiré, Roch K; Dowell, Floyd E; Foy, Brian D</p> <p>2017-11-07</p> <p>Understanding the age-structure of mosquito populations, especially malaria vectors such as Anopheles gambiae, is important for assessing the risk of infectious mosquitoes, and how vector control interventions may impact this risk. The use of near-infrared spectroscopy (NIRS) for age-grading has been demonstrated previously on laboratory and semi-field mosquitoes, but to date has not been utilized on wild-caught mosquitoes whose age is externally validated via parity status or parasite infection stage. In this study, we developed regression and classification models using NIRS on datasets of wild An. gambiae (s.l.) reared from larvae collected from the field in Burkina Faso, and two laboratory strains. We compared the accuracy of these models for predicting the ages of wild-caught mosquitoes that had been scored for their parity status as well as for positivity for Plasmodium sporozoites. Regression models utilizing variable selection increased predictive accuracy over the more common full-spectrum partial least squares (PLS) approach for cross-validation of the datasets, validation, and independent test sets. Models produced from datasets that included the greatest range of mosquito samples (i.e. different sampling locations and times) had the highest predictive accuracy on independent testing sets, though overall accuracy on these samples was low. For classification, we found that intramodel accuracy ranged between 73.5-97.0% for grouping of mosquitoes into "early" and "late" age classes, with the highest prediction accuracy found in laboratory colonized mosquitoes. However, this accuracy was decreased on test sets, with the highest classification of an independent set of wild-caught larvae reared to set ages being 69.6%. Variation in NIRS data, likely from dietary, genetic, and other factors limits the accuracy of this technique with wild-caught mosquitoes. Alternative algorithms may help improve prediction accuracy, but care should be taken to either maximize variety in models or minimize confounders.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018AIPC.1942e0103S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018AIPC.1942e0103S"><span>Experimental investigation of instability in optical and morphological properties of percolated gold thin film during ambient aging</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sudheer, Mukherjee, C.; Rai, S. K.; Rai, V. N.; Srivastava, A. K.</p> <p>2018-04-01</p> <p>Instability in morphological and optical properties of sputtered grown percolated gold (Au) film has been experimentally investigated during ambient aging. Optical absorbance of the film recorded at various stage of aging shows huge variation in the spectra. A schematic is drawn to explain aging-assist evolution in the morphology (dewetting) and correlated with the variation in optical properties. The validity of model is confirmed by X-ray reflectivity (XRR) techniques, performed for both as-deposited and aged samples. Furthermore, change in the color of Au thin film with aging also seen in the photographic images of the samples that also support the absorbance and XRR results.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/17980254','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/17980254"><span>External prognostic validations and comparisons of age- and gender-adjusted exercise capacity predictions.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kim, Esther S H; Ishwaran, Hemant; Blackstone, Eugene; Lauer, Michael S</p> <p>2007-11-06</p> <p>The purpose of this study was to externally validate the prognostic value of age- and gender-based nomograms and categorical definitions of impaired exercise capacity (EC). Exercise capacity predicts death, but its use in routine clinical practice is hampered by its close correlation with age and gender. For a median of 5 years, we followed 22,275 patients without known heart disease who underwent symptom-limited stress testing. Models for predicted or impaired EC were identified by literature search. Gender-specific multivariable proportional hazards models were constructed. Four methods were used to assess validity: Akaike Information Criterion (AIC), right-censored c-index in 100 out-of-bootstrap samples, the Nagelkerke Index R2, and calculation of calibration error in 100 bootstrap samples. There were 646 and 430 deaths in 13,098 men and 9,177 women, respectively. Of the 7 models tested in men, a model based on a Veterans Affairs cohort (predicted metabolic equivalents [METs] = 18 - [0.15 x age]) had the highest AIC and R2. In women, a model based on the St. James Take Heart Project (predicted METs = 14.7 - [0.13 x age]) performed best. Categorical definitions of fitness performed less well. Even after accounting for age and gender, there was still an important interaction with age, whereby predicted EC was a weaker predictor in older subjects (p for interaction <0.001 in men and 0.003 in women). Several methods describe EC accounting for age and gender-related differences, but their ability to predict mortality differ. Simple cutoff values fail to fully describe EC's strong predictive value.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017MNRAS.471.4194M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017MNRAS.471.4194M"><span>From K giants to G dwarfs: stellar lifetime effects on metallicity distributions derived from red giants</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Manning, Ellen M.; Cole, Andrew A.</p> <p>2017-11-01</p> <p>We examine the biases inherent to chemical abundance distributions when targets are selected from the red giant branch (RGB), using simulated giant branches created from isochrones. We find that even when stars are chosen from the entire colour range of RGB stars and over a broad range of magnitudes, the relative numbers of stars of different ages and metallicities, integrated over all stellar types, are not accurately represented in the giant branch sample. The result is that metallicity distribution functions derived from RGB star samples require a correction before they can be fitted by chemical evolution models. We derive simple correction factors for over- and under-represented populations for the limiting cases of single-age populations with a broad range of metallicities and of continuous star formation at constant metallicity; an important general conclusion is that intermediate-age populations (≈1-4 Gyr) are over-represented in RGB samples. We apply our models to the case of the Large Magellanic Cloud bar and show that the observed metallicity distribution underestimates the true number of metal-poor stars by more than 25 per cent; as a result, the inferred importance of gas flows in chemical evolution models could potentially be overestimated. The age- and metallicity-dependences of RGB lifetimes require careful modelling if they are not to lead to spurious conclusions about the chemical enrichment history of galaxies.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70034678','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70034678"><span>Potential effects of alpha-recoil on uranium-series dating of calcrete</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Neymark, L.A.</p> <p>2011-01-01</p> <p>Evaluation of paleosol ages in the vicinity of Yucca Mountain, Nevada, at the time the site of a proposed high-level nuclear waste repository, is important for fault-displacement hazard assessment. Uranium-series isotope data were obtained for surface and subsurface calcrete samples from trenches and boreholes in Midway Valley, Nevada, adjacent to Yucca Mountain. 230Th/U ages of 33 surface samples range from 1.3 to 423 thousand years (ka) and the back-calculated 234U/238U initial activity ratios (AR) are relatively constant with a mean value of 1.54 ± 0.15 (1σ), which is consistent with the closed-system behavior. Subsurface calcrete samples are too old to be dated by the 230Th/U method. U-Pb data for post-pedogenic botryoidal opal from a subsurface calcrete sample show that these subsurface calcrete samples are older than ~ 1.65 million years (Ma), old enough to have attained secular equilibrium had their U-Th systems remained closed. However, subsurface calcrete samples show U-series disequilibrium indicating open-system behavior of 238U daughter isotopes, in contrast with the surface calcrete, where open-system behavior is not evident. Data for 21 subsurface calcrete samples yielded calculable 234U/238U model ages ranging from 130 to 1875 ka (assuming an initial AR of 1.54 ± 0.15, the mean value calculated for the surface calcrete samples). A simple model describing continuous α-recoil loss predicts that the 234U/238U and 230Th/238U ARs reach steady-state values ~ 2 Ma after calcrete formation. Potential effects of open-system behavior on 230Th/U ages and initial 234U/238U ARs for younger surface calcrete were estimated using data for old subsurface calcrete samples with the 234U loss and assuming that the total time of water-rock interaction is the only difference between these soils. The difference between the conventional closed-system and open-system ages may exceed errors of the calculated conventional ages for samples older than ~ 250 ka, but is negligible for younger soils.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70000277','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70000277"><span>Seasonal variation in size-dependent survival of juvenile Atlantic salmon (Salmo salar): Performance of multistate capture-mark-recapture models</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Letcher, B.H.; Horton, G.E.</p> <p>2008-01-01</p> <p>We estimated the magnitude and shape of size-dependent survival (SDS) across multiple sampling intervals for two cohorts of stream-dwelling Atlantic salmon (Salmo salar) juveniles using multistate capture-mark-recapture (CMR) models. Simulations designed to test the effectiveness of multistate models for detecting SDS in our system indicated that error in SDS estimates was low and that both time-invariant and time-varying SDS could be detected with sample sizes of >250, average survival of >0.6, and average probability of capture of >0.6, except for cases of very strong SDS. In the field (N ??? 750, survival 0.6-0.8 among sampling intervals, probability of capture 0.6-0.8 among sampling occasions), about one-third of the sampling intervals showed evidence of SDS, with poorer survival of larger fish during the age-2+ autumn and quadratic survival (opposite direction between cohorts) during age-1+ spring. The varying magnitude and shape of SDS among sampling intervals suggest a potential mechanism for the maintenance of the very wide observed size distributions. Estimating SDS using multistate CMR models appears complementary to established approaches, can provide estimates with low error, and can be used to detect intermittent SDS. ?? 2008 NRC Canada.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21793691','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21793691"><span>Circadian typology, age, and the alternative five-factor personality model in an adult women sample.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Muro, Anna; Gomà-i-Freixanet, Montserrat; Adan, Ana; Cladellas, Ramon</p> <p>2011-10-01</p> <p>Research on personality and circadian typology indicates evening-type women are more impulsive and novelty seeking, neither types are more anxious, and morning types tend to be more active, conscientious, and persistent. The purpose of this study is to examine the differences between circadian typologies in the light of the Zuckerman's Alternative Five-Factor Model (AFFM) of personality, which has a strong biological basis, in an adult sample of 412 women 18 to 55 yrs of age. The authors found morning-type women had significant higher scores than evening-type and neither-type women on Activity, and its subscales General Activity and Work Activity. In contrast, evening-type women scored significantly higher than morning-type women on Aggression-Hostility, Impulsive Sensation Seeking, and its subscale Sensation Seeking. In all groups, results were independent of age. These findings are in accordance with those previously obtained in female student samples and add new data on the AFFM. The need of using personality models that are biologically based in the study of circadian rhythms is discussed.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li class="active"><span>5</span></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_5 --> <div id="page_6" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li class="active"><span>6</span></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="101"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24801657','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24801657"><span>Profile and determinants of successful aging in the Ibadan Study of Ageing.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Gureje, Oye; Oladeji, Bibilola D; Abiona, Taiwo; Chatterji, Somnath</p> <p>2014-05-01</p> <p>To determine the profile and determinants of successful aging in a developing country characterized by low life expectancy and where successful agers may represent a unique group. Community-based cohort study. Eight contiguous states in the Yoruba-speaking region of Nigeria. A multistage clustered sampling of households was used to select a representative sample of individuals (N = 2,149) aged 65 and older at baseline. Nine hundred thirty were successfully followed for an average of 64 months between August 2003 and December 2009. Lifestyle and behavioral factors were assessed at baseline. Successful aging, defined using each of three models (absence of chronic health conditions, functional independence, and satisfaction with life), was assessed at follow-up. Between 16% and 75% of respondents could be classified as successful agers using one of the three models while 7.5% could be so classified using a combination of all the models. Correlations between the three models were small, ranging from 0.08 to 0.15. Different features predicted their outcomes, suggesting that they represent relatively independent trajectories of aging. Whichever model was used, more men than women tended to be classified as aging successfully. Men who aged successfully, using a combination of all the three models, were more likely never to have smoked (adjusted odds ratio (aOR) = 4.7, 95% confidence interval (CI) = 1.55-14.46) and to report, at baseline, having contacts with friends (aOR = 4.2, 95% CI = 1.0-18.76) or participating in community activities (aOR = 16.0, 95% CI = 1.23-204.40). In women, there was a nonlinear trend for younger age at baseline to predict this outcome. Modifiable social and lifestyle factors predicted successful aging in this population, suggesting that health promotion targeting behavior change may lead to tangible benefits for health and well-being in old age. © 2014, Copyright the Authors Journal compilation © 2014, The American Geriatrics Society.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=ciencia&pg=2&id=EJ779164','ERIC'); return false;" href="https://eric.ed.gov/?q=ciencia&pg=2&id=EJ779164"><span>Testing Direct and Indirect Effects of Sports Participation on Perceived Health in Spanish Adolescents between 15 and 18 Years of Age</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Pastor, Yolanda; Balaguer, Isabel; Pons, Diana; Garcia-Merita, Marisa</p> <p>2003-01-01</p> <p>This paper examines the direct and indirect effects of sports participation on perceived health. It is based on a representative sample of middle adolescents aged 15-18 (N=1038, M AGE=16.31, S. D.=0.92; 510 boys and 528 girls) from the Valencian Community (Spain). This study used two different models; Model A is an adaptation of Thorlindsson,…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AGUFM.H21F1444J','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AGUFM.H21F1444J"><span>Regional Evaluation of Groundwater Age Distributions Using Lumped Parameter Models with Large, Sparse Datasets: Example from the Central Valley, California, USA</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Jurgens, B. C.; Bohlke, J. K.; Voss, S.; Fram, M. S.; Esser, B.</p> <p>2015-12-01</p> <p>Tracer-based, lumped parameter models (LPMs) are an appealing way to estimate the distribution of age for groundwater because the cost of sampling wells is often less than building numerical groundwater flow models sufficiently complex to provide groundwater age distributions. In practice, however, tracer datasets are often incomplete because of anthropogenic or terrigenic contamination of tracers, or analytical limitations. While age interpretations using such datsets can have large uncertainties, it may still be possible to identify key parts of the age distribution if LPMs are carefully chosen to match hydrogeologic conceptualization and the degree of age mixing is reasonably estimated. We developed a systematic approach for evaluating groundwater age distributions using LPMs with a large but incomplete set of tracer data (3H, 3Hetrit, 14C, and CFCs) from 535 wells, mostly used for public supply, in the Central Valley, California, USA that were sampled by the USGS for the California State Water Resources Control Board Groundwater Ambient Monitoring and Assessment or the USGS National Water Quality Assessment Programs. In addition to mean ages, LPMs gave estimates of unsaturated zone travel times, recharge rates for pre- and post-development groundwater, the degree of age mixing in wells, proportion of young water (<60 yrs), and the depth of the boundary between post-development and predevelopment groundwater throughout the Central Valley. Age interpretations were evaluated by comparing past nitrate trends with LPM predicted trends, and whether the presence or absence of anthropogenic organic compounds was consistent with model results. This study illustrates a practical approach for assessing groundwater age information at a large scale to reveal important characteristics about the age structure of a major aquifer, and of the water supplies being derived from it.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70015476','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70015476"><span>Petrology and age of alkalic lava from the Ratak Chain of the Marshall Islands</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Davis, A.S.; Pringle, M.S.; Pickthorn, L.-B.G.; Clague, D.A.; Schwab, W.C.</p> <p>1989-01-01</p> <p>Volcanic rock dredged from the flanks of four volcanic edifices in the Ratak chain of the Marshall Islands consist of alkalic lava that erupted above sea level or in shallow water. Compositions of recovered samples are predominantly differentiated alkalic basalt and hawaiite but include strongly alkalic melilitite. Whole rock 40Ar/39Ar total fusion and incremental heating ages of 87.3 ?? 0.6 Ma and 82.2 ?? 1.6 Ma determined for samples from Erikub Seamount and Ratak Guyot, respectively, are within the range predicted by plate rotation models but show no age progression consistent with a simple hot spot model. Variations in isotopic and some incompatible element ratios suggest interisland heterogeneity. -from Authors</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=curves+AND+Statistics&pg=5&id=EJ781404','ERIC'); return false;" href="https://eric.ed.gov/?q=curves+AND+Statistics&pg=5&id=EJ781404"><span>The Gifted Rating Scales-School Form: An Analysis of the Standardization Sample Based on Age, Gender, Race, and Diagnostic Efficiency</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Pfeiffer, Steven I.; Jarosewich, Tania</p> <p>2007-01-01</p> <p>This study analyzes the standardization sample of a new teacher rating scale designed to assist in the identification of gifted students. The Gifted Rating Scales-School Form (GRS-S) is based on a multidimensional model of giftedness. Results indicate no age or race/ethnicity differences on any of the scales and small but significant differences…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ902211.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ902211.pdf"><span>Perfectionism among Chinese Gifted and Nongifted Students in Hong Kong: The Use of the Revised Almost Perfect Scale</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Chan, David W.</p> <p>2011-01-01</p> <p>This study investigated the structure of perfectionism based on the almost Perfect Scale-Revised with a sample of 320 gifted students aged 7 to 12 and a sample of 882 nongifted students of similar ages in Hong Kong. Multigroup confirmatory factor analyses across the two student groups supported a common three-dimensional model that included…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016GeCoA.181..201F','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016GeCoA.181..201F"><span>XRD-based 40Ar/39Ar age correction for fine-grained illite, with application to folded carbonates in the Monterrey Salient (northern Mexico)</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Fitz-Díaz, Elisa; Hall, Chris M.; van der Pluijm, Ben A.</p> <p>2016-05-01</p> <p>Due to their minute size, 40Ar/39Ar analysis of illite faces significant analytical challenges, including mineral characterization and, especially, effects of grain size and crystallography on 39Ar recoil. Quantifying the effects of 39Ar recoil requires the use of sample vacuum encapsulation during irradiation, which permits the measurement of the fraction of recoiled 39Ar as well as the 39Ar and 40Ar∗ retained within illite crystals that are released during step heating. Total-Gas Ages (TGA) are calculated by using both recoiled and retained argon, which is functionally equivalent to K-Ar ages, while Retention Ages (RA) only involve retained Ar in the crystal. Natural applications have shown that TGA fits stratigraphic constraints of geological processes when the average illite crystallite thickness (ICT) is smaller than 10 nm, and that RA matches these constraints for ICTs larger than 50 nm. We propose a new age correction method that takes into account the average ICT and corresponding recoiled 39Ar for a sample, with X-ray Corrected Ages (XCA) lying between Total-Gas and Retention Ages depending on ICT. This correction is particularly useful in samples containing authigenic illite formed in the anchizone, with typical ICT values between 10 and 50 nm. In three samples containing authigenic illite from Cretaceous carbonates in the Monterrey Salient in northern Mexico, there is a range in TGAs among the different size-fractions of 46-49, 36-43 and 40-52 Ma, while RAs range from 54-64, 47-52 and 53-54 Ma, respectively. XCA calculations produce tighter age ranges for these samples of 52.5-56, 45.5-48.5 and 49-52.5 Ma, respectively. In an apparent age vs ICT or %2M 1illite plot, authigenic illite grains show a slope that is in general slightly positive for TGA, slightly negative for RA, but close to zero for XCA, with thinner crystallites showing more dispersion than thicker ones. In order to test if dispersion is due to a different formation history or the result of retention capability, degassing spectra were modeled for site XCA averages and overall XCA average. Modeling shows that local site age average best match the measured spectra, instead of a global average age, indicating that illite growth reflects local deformation, and is not the result of regional metamorphism. Modeling also shows that Ar-degassing spectra are very sensitive to grain size, such that age interpretation based on Ar-plateaus is meaningless for most fine-grained clays.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018JAESc.155..139Z','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018JAESc.155..139Z"><span>Fake age hiatus in a loess section revealed by OSL dating of calcrete nodules</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Zhang, Junjie; Li, Sheng-Hua; Sun, Jimin; Hao, Qingzhen</p> <p>2018-04-01</p> <p>Optically stimulated luminescence (OSL) dating on potassium feldspar has been performed with high resolution in the Luochuan section in the Chinese Loess Plateau. An age hiatus of ∼ 15 ka is found at the top of L2 layer within the loess/paleosol sequences. The age of the potassium feldspar from the calcrete nodules along the S1/L2 boundary is significantly older than those of the paleosol and loess samples lying above and below the boundary. The age overestimation of the potassium feldspar from calcrete nodules is caused by the underestimation of the dose rate, because accretion of carbonates could dilute the radioactivity. The age hiatus at the top of L2 also resulted from the underestimation of the dose rates of four loess samples beneath this hiatus. These four loess samples have high CaO concentrations. Ages of these samples are overestimated in the similar way as the nodules, but with smaller degrees. All results suggest that the accretion of carbonates happened after the loess deposition. The carbonate accretion process of the calcrete nodules has been simulated with accumulation models. The accretion can be as young as 46 ka, assuming the calcrete nodules formed rapidly at a certain time point. For slow and gradual accretion models, the carbonate started to accumulate slowly since the dust deposition and the accumulation became faster afterwards. The transition of the accretion rate may relate to the climate change or a change in the carbonate leaching and re-precipitation system.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=alcohol&pg=4&id=EJ942598','ERIC'); return false;" href="https://eric.ed.gov/?q=alcohol&pg=4&id=EJ942598"><span>Development and Correlates of Alcohol Use from Ages 13-20</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Duncan, Susan C.; Gau, Jeff M.; Duncan, Terry E.; Strycker, Lisa A.</p> <p>2011-01-01</p> <p>This study examined alcohol use development from ages 13-20 years. The sample comprised 256 youth (50.4% female; 51.2% White, 48.8% African American) assessed annually for 6 years. A cohort-sequential latent growth model was used to model categorical alcohol use (non-use vs. use). Covariates included gender, race, income, parent marital status,…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=age+AND+grouping&pg=4&id=EJ955240','ERIC'); return false;" href="https://eric.ed.gov/?q=age+AND+grouping&pg=4&id=EJ955240"><span>The Hierarchical Factor Model of ADHD: Invariant across Age and National Groupings?</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Toplak, Maggie E.; Sorge, Geoff B.; Flora, David B.; Chen, Wai; Banaschewski, Tobias; Buitelaar, Jan; Ebstein, Richard; Eisenberg, Jacques; Franke, Barbara; Gill, Michael; Miranda, Ana; Oades, Robert D.; Roeyers, Herbert; Rothenberger, Aribert; Sergeant, Joseph; Sonuga-Barke, Edmund; Steinhausen, Hans-Christoph; Thompson, Margaret; Tannock, Rosemary; Asherson, Philip; Faraone, Stephen V.</p> <p>2012-01-01</p> <p>Objective: To examine the factor structure of attention-deficit/hyperactivity disorder (ADHD) in a clinical sample of 1,373 children and adolescents with ADHD and their 1,772 unselected siblings recruited from different countries across a large age range. Hierarchical and correlated factor analytic models were compared separately in the ADHD and…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21211819','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21211819"><span>Analytical and sampling constraints in ²¹⁰Pb dating.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>MacKenzie, A B; Hardie, S M L; Farmer, J G; Eades, L J; Pulford, I D</p> <p>2011-03-01</p> <p>²¹⁰Pb dating provides a valuable, widely used means of establishing recent chronologies for sediments and other accumulating natural deposits. The Constant Rate of Supply (CRS) model is the most versatile and widely used method for establishing ²¹⁰Pb chronologies but, when using this model, care must be taken to account for limitations imposed by sampling and analytical factors. In particular, incompatibility of finite values for empirical data, which are constrained by detection limit and core length, with terms in the age calculation, which represent integrations to infinity, can generate erroneously old ages for deeper sections of cores. The bias in calculated ages increases with poorer limit of detection and the magnitude of the disparity increases with age. The origin and magnitude of this effect are considered below, firstly for an idealized, theoretical ²¹⁰Pb profile and secondly for a freshwater lake sediment core. A brief consideration is presented of the implications of this potential artefact for sampling and analysis. Copyright © 2011 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/909181','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/909181"><span>Yucca Mountain Area Saturated Zone Dissolved Organic Carbon Isotopic Data</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Thomas, James; Decker, David; Patterson, Gary</p> <p>2007-06-25</p> <p>Groundwater samples in the Yucca Mountain area were collected for chemical and isotopic analyses and measurements of water temperature, pH, specific conductivity, and alkalinity were obtained at the well or spring at the time of sampling. For this project, groundwater samples were analyzed for major-ion chemistry, deuterium, oxygen-18, and carbon isotopes of dissolved inorganic carbon (DIC) and dissolved organic carbon (DOC). The U.S. Geological Survey (USGS) performed all the fieldwork on this project including measurement of water chemistry field parameters and sample collection. The major ions dissolved in the groundwater, deuterium, oxygen-18, and carbon isotopes of dissolved inorganic carbon (DIC)more » were analyzed by the USGS. All preparation and processing of samples for DOC carbon isotopic analyses and geochemical modeling were performed by the Desert Research Institute (DRI). Analysis of the DOC carbon dioxide gas produced at DRI to obtain carbon-13 and carbon-14 values was conducted at the University of Arizona Accelerator Facility (a NSHE Yucca Mountain project QA qualified contract facility). The major-ion chemistry, deuterium, oxygen-18, and carbon isotopes of DIC were used in geochemical modeling (NETPATH) to determine groundwater sources, flow paths, mixing, and ages. The carbon isotopes of DOC were used to calculate groundwater ages that are independent of DIC model corrected carbon-14 ages. The DIC model corrected carbon-14 calculated ages were used to evaluate groundwater travel times for mixtures of water including water beneath Yucca Mountain. When possible, groundwater travel times were calculated for groundwater flow from beneath Yucca Mountain to down gradient sample sites. DOC carbon-14 groundwater ages were also calculated for groundwaters in the Yucca Mountain area. When possible, groundwater travel times were estimated for groundwater flow from beneath Yucca Mountain to down gradient groundwater sample sites using the DOC calculated groundwater ages. The DIC calculated groundwater ages were compared with DOC calculated groundwater ages and both of these ages were compared to travel times developed in ground-water flow and transport models. If nuclear waste is stored in Yucca Mountain, the saturated zone is the final barrier against the release of radionuclides to the environment. The most recent rendition of the TSPA takes little credit for the presence of the saturated zone and is a testament to the inadequate understanding of this important barrier. If radionuclides reach the saturated zone beneath Yucca Mountain, then there is a travel time before they would leave the Yucca Mountain area and flow down gradient to the Amargosa Valley area. Knowing how long it takes groundwater in the saturated zone to flow from beneath Yucca Mountain to down gradient areas is critical information for potential radionuclide transport. Radionuclide transport in groundwater may be the quickest pathway for radionuclides in the proposed Yucca Mountain repository to reach land surface by way of groundwater pumped in Amargosa Valley. An alternative approach to ground-water flow and transport models to determine the travel time of radionuclides from beneath Yucca Mountain to down gradient areas in the saturated zone is by carbon-14 dating of both inorganic and organic carbon dissolved in the groundwater. A standard method of determining ground-water ages is to measure the carbon-13 and carbon-14 of DIC in the groundwater and then correct the measured carbon-14 along a flow path for geochemical reactions that involve carbon containing phases. These geochemical reactions are constrained by carbon-13 and isotopic fractionations. Without correcting for geochemical reactions, the ground-water ages calculated from only the differences in carbon-14 measured along a flow path (assuming the decrease in carbon-14 is due strictly to radioactive decay) could be tens of thousands of years too old. The computer program NETPATH, developed by the USGS, is the best geochemical program for correcting carbon-14 activities for geochemical reactions. The DIC carbon-14 corrected ages can be further constrained by measuring the carbon isotopes of DOC. Because the only source of organic carbon in aquifers is almost always greater than 40,000 years old, any organic carbon that may be added to the groundwater would contain no carbon-14. Thus, ground-water ages determined by carbon isotopes of DOC should be maximum ages that can be used to constrain DIC corrected ages.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70035501','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70035501"><span>An evaluation of sex-age-kill (SAK) model performance</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Millspaugh, Joshua J.; Skalski, John R.; Townsend, Richard L.; Diefenbach, Duane R.; Boyce, Mark S.; Hansen, Lonnie P.; Kammermeyer, Kent</p> <p>2009-01-01</p> <p>The sex-age-kill (SAK) model is widely used to estimate abundance of harvested large mammals, including white-tailed deer (Odocoileus virginianus). Despite a long history of use, few formal evaluations of SAK performance exist. We investigated how violations of the stable age distribution and stationary population assumption, changes to male or female harvest, stochastic effects (i.e., random fluctuations in recruitment and survival), and sampling efforts influenced SAK estimation. When the simulated population had a stable age distribution and λ > 1, the SAK model underestimated abundance. Conversely, when λ < 1, the SAK overestimated abundance. When changes to male harvest were introduced, SAK estimates were opposite the true population trend. In contrast, SAK estimates were robust to changes in female harvest rates. Stochastic effects caused SAK estimates to fluctuate about their equilibrium abundance, but the effect dampened as the size of the surveyed population increased. When we considered both stochastic effects and sampling error at a deer management unit scale the resultant abundance estimates were within ±121.9% of the true population level 95% of the time. These combined results demonstrate extreme sensitivity to model violations and scale of analysis. Without changes to model formulation, the SAK model will be biased when λ ≠ 1. Furthermore, any factor that alters the male harvest rate, such as changes to regulations or changes in hunter attitudes, will bias population estimates. Sex-age-kill estimates may be precise at large spatial scales, such as the state level, but less so at the individual management unit level. Alternative models, such as statistical age-at-harvest models, which require similar data types, might allow for more robust, broad-scale demographic assessments.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016EGUGA..1816034L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016EGUGA..1816034L"><span>Apatite (U-Th-Sm)/He age dispersion arising from analysis of variable grain sizes and broken crystals - examples from the Scottish Southern Uplands</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Łuszczak, Katarzyna; Persano, Cristina; Stuart, Finlay; Brown, Roderick</p> <p>2016-04-01</p> <p>Apatite (U-Th-Sm)/He (AHe) thermochronometry is a powerful technique for deciphering denudation of the uppermost crust. However, the age dispersion of single grains from the same rock is typical, and this hampers establishing accurate thermal histories when low grain numbers are analysed. Dispersion arising from the analysis of broken crystal fragments[1] has been proposed as an important cause of age dispersion, along with grain size and radiation damage. A new tool, Helfrag[2], allows constraints to be placed on the low temperature history derived from the analysis of apatite crystal fragments. However, the age dispersion model has not been fully tested on natural samples yet. We have performed AHe analysis of multiple (n = 20-25) grains from four rock samples from the Scottish Southern Uplands, which were subjected to the same exhumation episodes, although, the amount of exhumation varied between the localities. This is evident from the range of AFT ages (˜60 to ˜200 Ma) and variable thermal histories showing either strong, moderate and no support for a rapid cooling event at ˜60 Ma. Different apatite size and fragment geometry were analysed in order to maximise age dispersion. In general, the age dispersion increases with increasing AFT age (from 47% to 127%), consistent with the prediction from the fragmentation model. Thermal histories obtained using Helfrag were compared with those obtained by standard codes based on the spherical approximation. In one case, the Helfrag model was capable of resolving the higher complexity of the thermal history of the rock, constraining several heating/cooling events that are not predicted by the standard models, but are in good agreement with the regional geology. In other cases, the thermal histories are similar for both Helfrag and standard models and the age predictions for the Helfrag are only slightly better than for standard model, implying that the grain size has the dominant role in generating the age dispersion. Rather than suggesting that grain size is the predominant factor in controlling age dispersion in all data sets, our results may be linked to the actual size of the picked grains; for grain widths smaller than 100 μm, the He profile within the crystal may not be differentiated enough to produce a dispersion measureable outside the uncertainty associated with the age. It is also easier for long-thin and short-thick than long-thick and short-thin grains to be preserved; this minimises the age dispersion that can be generated from fragmentation. We suggest, that in order to obtain valuable information from both fragmentation and grain size >20 large (width >100 μm) grain fragments of variable length have to be analyzed, together with a few smaller grains. Our results point to a strategy that favours multiple single-grain AHe ages determinations on carefully selected samples, with good quality apatite crystals of variable dimensions rather than fewer determinations on many samples. [1] Brown, R. et al. 2013.Geochim. Cosmochim. Acta.122, 478-497 [2] Beucher, R. et al. 2013.Geochim. Cosmochim. Acta. 120, 395-416.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18194048','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18194048"><span>The Model Human Processor and the older adult: parameter estimation and validation within a mobile phone task.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Jastrzembski, Tiffany S; Charness, Neil</p> <p>2007-12-01</p> <p>The authors estimate weighted mean values for nine information processing parameters for older adults using the Card, Moran, and Newell (1983) Model Human Processor model. The authors validate a subset of these parameters by modeling two mobile phone tasks using two different phones and comparing model predictions to a sample of younger (N = 20; M-sub(age) = 20) and older (N = 20; M-sub(age) = 69) adults. Older adult models fit keystroke-level performance at the aggregate grain of analysis extremely well (R = 0.99) and produced equivalent fits to previously validated younger adult models. Critical path analyses highlighted points of poor design as a function of cognitive workload, hardware/software design, and user characteristics. The findings demonstrate that estimated older adult information processing parameters are valid for modeling purposes, can help designers understand age-related performance using existing interfaces, and may support the development of age-sensitive technologies.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28679478','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28679478"><span>A prospective analysis of the role of cognition in three models of aging and schizophrenia.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Cohen, Carl I; Murante, Tessa</p> <p>2017-07-02</p> <p>This study uses longitudinal data from a sample of older adults with schizophrenia spectrum disorder (OAS) to examine the role of cognition in 3 models of aging and schizophrenia-accelerated aging, paradoxical aging, and heterogeneity of course-and their clinical relevance. The sample consisted of 103 community-dwelling persons aged 55 and over (mean=61years) with early-onset schizophrenia. Mean follow-up was 52.5months (range: 12-116months); 55% were men; 55% were white. We identified 21 potential predictor variables and used the Dementia Rating Scale (DRS) to assess cognition. There were no significant differences in the DRS at baseline (T1) and follow-up (T2). However, 20%, 22% and 58% of persons exhibited >0.5 effect size increase or decrease, or no change in their DRS scores, respectively; 19% were rapid decliners (>-2.11pts/year) and 19% were rapid improvers (>+2.11pts/year). In multivariable analysis, there were 3 predictors of higher DRS (T2): DRS (T1), decline in anxiety score, and race (white). The heterogeneity model best characterized the trajectory of cognition in later life. The accelerated aging model did not represent typical cognitive trajectories since most individuals were stable or improved. The heterogeneous trajectories made it difficult to generalize about cognition's role in the paradoxical aging model. Despite the paucity of predictors, our findings suggested that it may be clinically productive to enlist remediation strategies that target anxiety and cognition, and direct more attention to non-white OAS. Copyright © 2017. Published by Elsevier B.V.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014AGUFMEP23G..07W','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014AGUFMEP23G..07W"><span>Quantifying the influence of sediment source area sampling on detrital thermochronometer data</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Whipp, D. M., Jr.; Ehlers, T. A.; Coutand, I.; Bookhagen, B.</p> <p>2014-12-01</p> <p>Detrital thermochronology offers a unique advantage over traditional bedrock thermochronology because of its sensitivity to sediment production and transportation to sample sites. In mountainous regions, modern fluvial sediment is often collected and dated to determine the past (105 to >107 year) exhumation history of the upstream drainage area. Though potentially powerful, the interpretation of detrital thermochronometer data derived from modern fluvial sediment is challenging because of spatial and temporal variations in sediment production and transport, and target mineral concentrations. Thermochronometer age prediction models provide a quantitative basis for data interpretation, but it can be difficult to separate variations in catchment bedrock ages from the effects of variable basin denudation and sediment transport. We present two examples of quantitative data interpretation using detrital thermochronometer data from the Himalaya, focusing on the influence of spatial and temporal variations in basin denudation on predicted age distributions. We combine age predictions from the 3D thermokinematic numerical model Pecube with simple models for sediment sampling in the upstream drainage basin area to assess the influence of variations in sediment production by different geomorphic processes or scaled by topographic metrics. We first consider a small catchment from the central Himalaya where bedrock landsliding appears to have affected the observed muscovite 40Ar/39Ar age distributions. Using a simple model of random landsliding with a power-law landslide frequency-area relationship we find that the sediment residence time in the catchment has a major influence on predicted age distributions. In the second case, we compare observed detrital apatite fission-track age distributions from 16 catchments in the Bhutan Himalaya to ages predicted using Pecube and scaled by various topographic metrics. Preliminary results suggest that predicted age distributions scaled by the rock uplift rate in Pecube are statistically equivalent to the observed age distributions for ~75% of the catchments, but may improve when scaled by local relief or specific stream power weighted by satellite-derived precipitation. Ongoing work is exploring the effect of scaling by other topographic metrics.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26730383','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26730383"><span>Verification of relationship model between Korean new elderly class's recovery resilience and productive aging.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Cho, Gun-Sang; Kim, Dae-Sung; Yi, Eun-Surk</p> <p>2015-12-01</p> <p>The purpose of this study is to verification of relationship model between Korean new elderly class's recovery resilience and productive aging. As of 2013, this study sampled preliminary elderly people in Gyeonggi-do and other provinces nationwide. Data from a total of effective 484 subjects was analyzed. The collected data was processed using the IBM SPSS 20.0 and AMOS 20.0, and underwent descriptive statistical analysis, confirmatory factor analysis, and structure model verification. The path coefficient associated with model fitness was examined. The standardization path coefficient between recovery resilience and productive aging is β=0.975 (t=14.790), revealing a statistically significant positive effect. Thus, it was found that the proposed basic model on the direct path of recovery resilience and productive aging was fit for the model.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4697781','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4697781"><span>Verification of relationship model between Korean new elderly class’s recovery resilience and productive aging</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Cho, Gun-Sang; Kim, Dae-Sung; Yi, Eun-Surk</p> <p>2015-01-01</p> <p>The purpose of this study is to verification of relationship model between Korean new elderly class’s recovery resilience and productive aging. As of 2013, this study sampled preliminary elderly people in Gyeonggi-do and other provinces nationwide. Data from a total of effective 484 subjects was analyzed. The collected data was processed using the IBM SPSS 20.0 and AMOS 20.0, and underwent descriptive statistical analysis, confirmatory factor analysis, and structure model verification. The path coefficient associated with model fitness was examined. The standardization path coefficient between recovery resilience and productive aging is β=0.975 (t=14.790), revealing a statistically significant positive effect. Thus, it was found that the proposed basic model on the direct path of recovery resilience and productive aging was fit for the model. PMID:26730383</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70019779','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70019779"><span>The history of a continent from U-Pb ages of zircons from Orinoco River sand and Sm-Nd isotopes in Orinoco basin river sediments</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Goldstein, S.L.; Arndt, N.T.; Stallard, R.F.</p> <p>1997-01-01</p> <p>We report SHRIMP U-Pb ages of 49 zircons from a sand sample from the lower Orinoco River, Venezuela, and Nd model ages of the fine sediment load from the main river and tributaries. The U-Pb ages reflect individual magmatic or metamorphic events, the Sm-Nd model ages reflect average crustal-residence ages of the sediment sources. Together they allow delineation of the crust-formation history of the basement precursors of the sediments. The U-Pb ages range from 2.83 to 0.15 Ga, and most are concordant or nearly so. Discrete age groupings occur at ??? 2.8, ??? 2.1, and ??? 1.1 Ga. The oldest group contains only three samples but is isolated from its closest neighbors by a ??? 600 Ma age gap. Larger age groupings at ??? 2.1 and ??? 1.1 Ga make up about a third and a quarter of the total number of analyses, respectively. The remaining analyses scatter along concordia, and most are younger than 1.6 Ga. The ??? 2.8 and ??? 2.1 Ga ages correspond to periods of crust formation of the Imataca and Trans-Amazonian provinces of the Guyana Shield, respectively, and record intervals of short but intensive continental growth. These ages coincide with ??? 2.9 and ??? 2.1 Ga Nd model ages of sediments from tributaries draining the Archean and Proterozoic provinces of the Guyana Shield, respectively, indicating that the U-Pb ages record the geological history of the crystalline basement of the Orinoco basin. Zircons with ages corresponding to the major orogenies of the North Atlantic continents (the Superior at ??? 2.7 Ga and Hudsonian at 1.7-1.9 Ga) were not found in the Orinoco sample. The age distribution may indicate that South and North America were separated throughout their history. Nd model ages of sediments from the lower Orinoco River and Andean tributaries are ??? 1.9 Ga, broadly within the range displayed by major rivers and dusts. This age does not coincide with known thermal events in the region and reflects mixing of sources with different crust-formation ages. The igneous and metamorphic history of these sources, as recorded by the detrital zircons, is that of the Orinoco basin basement. This implies that, despite evidence of fast sedimentary recycling, global similarities in Nd crustal-residence ages, and the probability of cross-continent mixing through continental drift, the sedimentary material carried by individual rivers is mainly derived from the crystalline basement in the basin. The global semblance in Nd isotope ratios in major river sediments and atmospheric dusts results from the averaging effect of large-scale sampling of the continents, which are heterogeneous in age on smaller regional scales. A large portion of the continental crust in the Orinoco basin formed during the Trans-Amazonian orogeny at 2.0-2.1 Ga, and smaller portions formed both earlier, at ??? 2.8 Ga, and later, after 1.6 Ga. These observations, which are consistent with the relative sizes of crustal age provinces in the Orinoco basin, indicate that sediments from the lower Orinoco and Andean tributaries contain 25-35% of material added to the crust since Trans-Amazonian times. Nd model ages of these sediments underestimate the average crust-formation age of the basement of the Orinoco basin by only about 10%. If this relationship holds in other river basins, then Nd model ages of major rivers and wind blown particulates indicate that the mean age of the continental crust is ??? 1.9-2 Ga. ?? 1997 Elsevier Science B.V.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li class="active"><span>6</span></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_6 --> <div id="page_7" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li class="active"><span>7</span></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="121"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23727994','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23727994"><span>A multi-level model of blood lead as a function of air lead.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Richmond-Bryant, Jennifer; Meng, Qingyu; Davis, J Allen; Cohen, Jonathan; Svendsgaard, David; Brown, James S; Tuttle, Lauren; Hubbard, Heidi; Rice, Joann; Kirrane, Ellen; Vinikoor-Imler, Lisa; Kotchmar, Dennis; Hines, Erin; Ross, Mary</p> <p>2013-09-01</p> <p>National and local declines in lead (Pb) in blood (PbB) over the past several years coincide with the decline in ambient air Pb (PbA) concentrations. The objective of this work is to evaluate how the relationship between PbB levels and PbA levels has changed following the phase out of leaded gasoline and tightened controls on industrial Pb emissions over the past 30 years among a national population sample. Participant-level data from the National Health and Nutrition Examination Survey (NHANES) were employed for two time periods (1988-1994 and 1999-2008), and the model was corrected for housing, demographic, socioeconomic, and other covariates present in NHANES. NHANES data for PbB and covariates were merged with PbA data from the U.S. Environmental Protection Agency. Linear mixed effects models (LMEs) were run to assess the relationship of PbB with PbA; sample weights were omitted, given biases encountered with the use of sample weights in LMEs. The 1988-1994 age-stratified results found that ln(PbB) was statistically significantly associated with ln(PbA) for all age groups. The consistent influence of PbA on PbB across age groups for the years 1988-1994 suggests a ubiquitous exposure unrelated to age of the sample population. The comparison of effect estimates for ln(PbA) shows a statistically significant effect estimate and ANOVA results for ln(PbB) for the 6- to 11-year and 12- to 19-year age groups during 1999-2008. The more recent finding suggests that PbA has less consistent influence on PbB compared with other factors. Copyright © 2013 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=Siblings+AND+relationship+AND+cognitive+AND+development&pg=4&id=EJ235500','ERIC'); return false;" href="https://eric.ed.gov/?q=Siblings+AND+relationship+AND+cognitive+AND+development&pg=4&id=EJ235500"><span>Evaluation of Confluence Model Variables on IQ and Achievement Test Scores in a Sample of 6- to 11-Year-Old Children.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Svanum, Soren; Bringle, Robert G.</p> <p>1980-01-01</p> <p>The confluence model of cognitive development was tested on 7,060 children. Family size, sibling order within family sizes, and hypothesized age-dependent effects were tested. Findings indicated an inverse relationship between family size and the cognitive measures; age-dependent effects and other confluence variables were found to be…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=kaufman&pg=2&id=EJ1156648','ERIC'); return false;" href="https://eric.ed.gov/?q=kaufman&pg=2&id=EJ1156648"><span>Exploring the Latent Structure of the Luria Model for the KABC-II at School Age: Further Insights from Confirmatory Factor Analysis</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>McGill, Ryan J.</p> <p>2017-01-01</p> <p>The present study examined the factor structure of the Luria interpretive model for the Kaufman Assessment Battery for Children-Second Edition (KABC-II) with normative sample participants aged 7-18 (N = 2,025) using confirmatory factor analysis with maximum-likelihood estimation. For the eight subtest Luria configuration, an alternative…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=social+AND+media+AND+good&pg=3&id=EJ950747','ERIC'); return false;" href="https://eric.ed.gov/?q=social+AND+media+AND+good&pg=3&id=EJ950747"><span>Media Exposure, Body Dissatisfaction, and Disordered Eating in Middle-Aged Women: A Test of the Sociocultural Model of Disordered Eating</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Slevec, Julie; Tiggemann, Marika</p> <p>2011-01-01</p> <p>The primary aim of our study was to examine the influence of media exposure on body dissatisfaction and disordered eating in middle-aged women. A sample of 101 women, aged between 35 and 55 years, completed questionnaire measures of media exposure, thin-ideal internalization, social comparison, appearance investment, aging anxiety, body…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016GeCoA.178...20O','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016GeCoA.178...20O"><span>230Th/U dating of Last Interglacial brain corals from Bonaire (southern Caribbean) using bulk and theca wall material</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Obert, J. Christina; Scholz, Denis; Felis, Thomas; Brocas, William M.; Jochum, Klaus P.; Andreae, Meinrat O.</p> <p>2016-04-01</p> <p>We compared the suitability of two skeletal materials of the Atlantic brain coral Diploria strigosa for 230Th/U-dating: the commonly used bulk material comprising all skeletal elements and the denser theca wall material. Eight fossil corals of presumably Last Interglacial age from Bonaire, southern Caribbean Sea, were investigated, and several sub-samples were dated from each coral. For four corals, both the ages and the activity ratios of the bulk material and theca wall agree within uncertainty. Three corals show significantly older ages for their bulk material than for their theca wall material as well as substantially elevated 232Th content and (230Th/238U) ratios. The bulk material samples of another coral show younger ages and lower (230Th/238U) ratios than the corresponding theca wall samples. This coral also contains a considerable amount of 232Th. The application of the available open-system models developed to account for post-depositional diagenetic effects in corals shows that none of the models can successfully be applied to the Bonaire corals. The most likely explanation for this observation is that the assumptions of the models are not fulfilled by our data set. Comparison of the theca wall and bulk material data enables us to obtain information about the open-system processes that affected the corals. The corals showing apparently older ages for their bulk material were probably affected by contamination with a secondary (detrital) phase. The most likely source of the detrital material is carbonate sand. The higher (230Th/232Th) ratio of this material implies that detrital contamination would have a much stronger impact on the ages than a contaminant with a bulk Earth (230Th/232Th) ratio and that the threshold for the commonly applied 232Th reliability criterion would be much lower than the generally used value of 1 ng g-1. The coral showing apparently younger ages for its bulk material was probably influenced by more than one diagenetic process. A potential scenario is a combination of detrital contamination and U addition by secondary pore infillings. Our results show that the dense theca wall material of D. strigosa is generally less affected by post-depositional open-system behaviour and better suited for 230Th/U-dating than the bulk material. This is also obvious from the fact that all ages of theca wall material reflect a Last Interglacial origin (∼125 ka), whereas the bulk material samples are either substantially older or younger. However, for some corals, the 230Th/U-ages and activity ratios of the bulk material and the theca wall samples are similar. This shows that strictly reliable 230Th/U-ages can also be obtained from bulk material samples of exceptionally well-preserved corals. However, the bulk material samples more frequently show elevated activity ratios and ages than the corresponding theca wall samples. Our findings should be generally applicable to brain corals (Mussidae) that are found in tropical oceans worldwide and may enable reliable 230Th/U-dating of fossil corals with similar skeletal architecture, even if their bulk skeleton is altered by diagenesis. The 230Th/U-ages we consider reliable (120-130 ka), along with a recently published age of 118 ka, provide the first comprehensive dating of the elevated lower reef terrace at Bonaire (118-130 ka), which is in agreement in timing and duration with other Last Interglacial records.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2009PhDT.......138P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2009PhDT.......138P"><span>Low-temperature thermochronology of the Laramide Ranges and eastward translation of shortening in the Sevier Belt, Wyoming, Utah and Montana</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Peyton, Sara Lynn</p> <p></p> <p>This dissertation contains two studies that use very different techniques to investigate the Mesozoic and Cenozoic tectonics of the western USA. The first study investigates shortening in the Sevier thrust belt of northeast Utah and southwest Wyoming using cross sections and seismic reflection data. The second study investigates the low-temperature thermochronology of the Laramide Ranges using apatite (U-Th)/He dating. We used cross sections and seismic reflection data to investigate bed length discrepancies within the hanging wall of the Absaroka thrust in the Sevier thrust belt of northeast Utah and southwest Wyoming. Restoration of cross sections suggests that there was ˜8-14 km of pre-Absaroka-thrust shortening above the Jurassic Preuss salt detachment, but not below it, in the hanging wall of the Absaroka thrust. Reflection seismic data over the hanging wall of the Crawford thrust show that the Crawford thrust is not offset along the Preuss salt detachment, indicating that the additional shortening on the Absaroka plate was transferred east before main movement on the Crawford thrust. Although early displacement on the Crawford thrust cannot be ruled out as the cause of the extra shortening, surface and subsurface geology suggests slip from the western thrust system (Willard and Lost Creek thrusts) was transferred several tens of kilometers east along the Jurassic Preuss salt detachment between ˜102-90 Ma, to the future location of the Absaroka thrust hanging wall. The lack of deformation of the Crawford thrust on the seismic data, along with shortening and extension estimates from cross sections, also indicate that the magnitude of Paleocene and post-early Eocene shortening on the Medicine Butte thrust was essentially offset by subsequent extension on the middle Eocene to late Oligocene Almy-Acocks normal-fault system. For the second study in this dissertation, we dated 91 borehole and surface samples from Laramide-age, basement-cored uplifts of the Rocky Mountain foreland (Wind River, Beartooth, Bighorn and Laramie Ranges) and the Uncompahgre Uplift using the apatite (U-Th)/He system. Apatite (U-Th)/He ages generally decrease with increasing subsurface depth (decreasing elevation) and most samples show age dispersion ranging from tens to hundreds of Myr. Additionally, several samples show correlations between apatite (U-Th)/He age and effective U concentration (eU = [U] + 0.235[Th]) of the crystal, indicating that radiation damage has affected He diffusivity, and hence (U-Th)/ He age. Many surface and near-surface samples have apatite (U-Th)/He ages that are older than corresponding apatite fission-track ages. Forward modeling of Laramide-type thermal histories using a radiation damage diffusion model showed that (U-Th)/He ages may be widely dispersed, and may be older than corresponding apatite fission-track ages within a fossil He partial retention zone. Most of our samples, however, do not show the correlation between (U-Th)/He age and eU predicted by radiation damage diffusion models. We investigated the influence of both grain size and eU content and show that the effects of grain size can obscure (U-Th)/ He age-eU correlations and, similarly, the effect of eU variation can obscure (U-Th)/ He age-grain size correlations. (U-Th)/He ages that are older than fission-track ages from high peaks in the Wind River Range, and from some samples from the Beartooth Range, are most likely the result of He implantation from high eU phases. Best-fit thermal histories from the inversion of age-eU pairs were extrapolated to other elevations to create model age-elevation profiles for a range of eU concentrations. These model profiles approximate our real data. Inverse modeling of (U-Th)/He age data suggests that rapid exhumation within the Laramide province likely began earlier in the Bighorn Mountains (before ˜71 Ma) than the Beartooth Range (before ˜58 Ma), and that the borehole at the northern end of the Laramie Range penetrated a fault sliver at depth.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25728882','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25728882"><span>Confirmatory factor analysis and measurement invariance of the Child Feeding Questionnaire in low-income Hispanic and African-American mothers with preschool-age children.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kong, Angela; Vijayasiri, Ganga; Fitzgibbon, Marian L; Schiffer, Linda A; Campbell, Richard T</p> <p>2015-07-01</p> <p>Validation work of the Child Feeding Questionnaire (CFQ) in low-income minority samples suggests a need for further conceptual refinement of this instrument. Using confirmatory factor analysis, this study evaluated 5- and 6-factor models on a large sample of African-American and Hispanic mothers with preschool-age children (n = 962). The 5-factor model included: 'perceived responsibility', 'concern about child's weight', 'restriction', 'pressure to eat', and 'monitoring' and the 6-factor model also tested 'food as a reward'. Multi-group analysis assessed measurement invariance by race/ethnicity. In the 5-factor model, two low-loading items from 'restriction' and one low-variance item from 'perceived responsibility' were dropped to achieve fit. Only removal of the low-variance item was needed to achieve fit in the 6-factor model. Invariance analyses demonstrated differences in factor loadings. This finding suggests African-American and Hispanic mothers may vary in their interpretation of some CFQ items and use of cognitive interviews could enhance item interpretation. Our results also demonstrated that 'food as a reward' is a plausible construct among a low-income minority sample and adds to the evidence that this factor resonates conceptually with parents of preschoolers; however, further testing is needed to determine the validity of this factor with older age groups. Copyright © 2015 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/ED532916.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/ED532916.pdf"><span>Boosting Early Development: The Mixed Effects of Kindergarten Enrollment Age</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Zhang, Jiahui; Xin, Tao</p> <p>2012-01-01</p> <p>This study aimed to investigate the effects of kindergarten enrollment age on four-year-old Chinese children's early cognition and problem behavior using multilevel models. The sample comprised of 1,391 pre-school children (the mean age is 4.58 years old) from 74 kindergartens in six different provinces. The results demonstrated curvilinear…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20108898','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20108898"><span>Systematic identification of yeast proteins extracted into model wine during aging on the yeast lees.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Rowe, Jeffrey D; Harbertson, James F; Osborne, James P; Freitag, Michael; Lim, Juyun; Bakalinsky, Alan T</p> <p>2010-02-24</p> <p>Total protein and protein-associated mannan concentrations were measured, and individual proteins were identified during extraction into model wines over 9 months of aging on the yeast lees following completion of fermentations by seven wine strains of Saccharomyces cerevisiae. In aged wines, protein-associated mannan increased about 6-fold (+/-66%), while total protein only increased 2-fold (+/-20%), which resulted in a significantly greater protein-associated mannan/total protein ratio for three strains. A total of 219 proteins were identified among all wine samples taken over the entire time course. Of the 17 "long-lived" proteins detected in all 9 month samples, 13 were cell wall mannoproteins, and four were glycolytic enzymes. Most cytosolic proteins were not detected after 6 months. Native mannosylated yeast invertase was assayed for binding to wine tannin and was found to have a 10-fold lower affinity than nonglycosylated bovine serum albumin. Enrichment of mannoproteins in the aged model wines implies greater solution stability than other yeast proteins and the possibility that their contributions to wine quality may persist long after bottling.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24998606','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24998606"><span>Relative age effects in fitness testing in a general school sample: how relative are they?</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Veldhuizen, Scott; Cairney, John; Hay, John; Faught, Brent</p> <p>2015-01-01</p> <p>When children or adolescents are grouped by age or year of birth, older individuals tend to outperform younger ones. These phenomena are known as relative age effects (RAEs). RAEs may result directly from differences in maturation, but may also be associated with psychological, pedagogic or other factors. In this article, we attempt to quantify RAEs in a simple fitness task and to identify the mechanisms operating. Data come from a 5-year study of 2278 individuals that included repeated administrations of the 20 m shuttle run. We use mixed-effect modelling to characterise change over time and then examine residuals from these models for evidence of an effect for age relative to peers or for season of birth. Age alone appears to account for RAEs in our sample, with no effects for age relative to peers or month of birth. Age grouping produces large disparities for girls under 12, moderate ones for boys of all ages and negligible ones for girls between 12 and 15. RAEs for this task and population appear to arise from simple age differences. Similar methods may be useful in determining whether other explanations of RAEs are necessary in other contexts. Evaluation processes that take age into account have the potential to mitigate RAEs in general settings.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013AIPC.1567..500P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013AIPC.1567..500P"><span>The strain path dependence of plastic deformation response of AA5754: Experiment and modeling</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Pham, Minh-Son; Hu, Lin; Iadicola, Mark; Creuziger, Adam; Rollett, Anthony D.</p> <p>2013-12-01</p> <p>This work presents modeling of experiments on a balanced biaxial (BB) pre-strained AA5754 alloy, subsequently reloaded uniaxially along the rolling direction and transverse direction. The material exhibits a complex plastic deformation response during the change in strain path due to 1) crystallographic texture, 2) aging (interactions between dislocations and Mg atoms) and 3) recovery (annihilation and re-arrangement of dislocations). With a BB prestrain of about 5 %, the aging process is dominant, and the yield strength for uniaxially deformed samples is observed to be higher than the flow stress during BB straining. The strain hardening rate after changing path is, however, lower than that for pre-straining. Higher degrees of pre-straining make the dynamic recovery more active. The dynamic recovery at higher strain levels compensates for the aging effect, and results in: 1) a reduction of the yield strength, and 2) an increase in the hardening rate of re-strained specimens along other directions. The yield strength of deformed samples is further reduced if these samples are left at room temperature to let static recovery occur. The synergistic influences of texture condition, aging and recovery processes on the material response make the modeling of strain path dependence of mechanical behavior of AA5754 challenging. In this study, the influence of crystallographic texture is taken into account by incorporating the latent hardening into a visco-plastic self-consistent model. Different strengths of dislocation glide interaction models in 24 slip systems are used to represent the latent hardening. Moreover, the aging and recovery effects are also included into the latent hardening model by considering strong interactions between dislocations and dissolved atom Mg and the microstructural evolution. These microstructural considerations provide a powerful capability to successfully describe the strain path dependence of plastic deformation behavior of AA5754.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018MNRAS.477.2326F','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018MNRAS.477.2326F"><span>Age-resolved chemistry of red giants in the solar neighbourhood</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Feuillet, Diane K.; Bovy, Jo; Holtzman, Jon; Weinberg, David H.; García-Hernández, D.; Hearty, Fred R.; Majewski, Steven R.; Roman-Lopes, Alexandre; Rybizki, Jan; Zamora, Olga</p> <p>2018-06-01</p> <p>In the age of high-resolution spectroscopic stellar surveys of the Milky Way, the number of stars with detailed abundances of multiple elements is rapidly increasing. These elemental abundances are directly influenced by the evolutionary history of the Galaxy, but this can be difficult to interpret without an absolute timeline of the abundance enrichment. We present age-abundance trends for [M/H], [α/M], and 17 individual elements using a sample of 721 solar neighbourhood Hipparcos red giant stars observed by Apache Point Observatory Galactic Evolution Experiment. These age trends are determined through a Bayesian hierarchical modelling method presented by Feuillet et al. We confirm that the [α/M]-age relation in the solar neighbourhood is steep and relatively narrow (0.20 dex age dispersion), as are the [O/M]-age and [Mg/M]-age relations. The age trend of [C/N] is steep and smooth, consistent with stellar evolution. The [M/H]-age relation has a mean age dispersion of 0.28 dex and a complex overall structure. The oldest stars in our sample are those with the lowest and highest metallicities, while the youngest stars are those with solar metallicity. These results provide strong constraints on theoretical models of Galactic chemical evolution (GCE). We compare them to the predictions of one-zone GCE models and multizone mixtures, both analytic and numerical. These comparisons support the hypothesis that the solar neighbourhood is composed of stars born at a range of Galactocentric radii, and that the most metal-rich stars likely migrated from a region with earlier and more rapid star formation such as the inner Galaxy.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28557469','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28557469"><span>Using implicit association tests in age-heterogeneous samples: The importance of cognitive abilities and quad model processes.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Wrzus, Cornelia; Egloff, Boris; Riediger, Michaela</p> <p>2017-08-01</p> <p>Implicit association tests (IATs) are increasingly used to indirectly assess people's traits, attitudes, or other characteristics. In addition to measuring traits or attitudes, IAT scores also reflect differences in cognitive abilities because scores are based on reaction times (RTs) and errors. As cognitive abilities change with age, questions arise concerning the usage and interpretation of IATs for people of different age. To address these questions, the current study examined how cognitive abilities and cognitive processes (i.e., quad model parameters) contribute to IAT results in a large age-heterogeneous sample. Participants (N = 549; 51% female) in an age-stratified sample (range = 12-88 years) completed different IATs and 2 tasks to assess cognitive processing speed and verbal ability. From the IAT data, D2-scores were computed based on RTs, and quad process parameters (activation of associations, overcoming bias, detection, guessing) were estimated from individual error rates. Substantial IAT scores and quad processes except guessing varied with age. Quad processes AC and D predicted D2-scores of the content-specific IAT. Importantly, the effects of cognitive abilities and quad processes on IAT scores were not significantly moderated by participants' age. These findings suggest that IATs seem suitable for age-heterogeneous studies from adolescence to old age when IATs are constructed and analyzed appropriately, for example with D-scores and process parameters. We offer further insight into how D-scoring controls for method effects in IATs and what IAT scores capture in addition to implicit representations of characteristics. (PsycINFO Database Record (c) 2017 APA, all rights reserved).</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70032695','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70032695"><span>Calibration of amino acid racemization (AAR) kinetics in United States mid-Atlantic Coastal Plain Quaternary mollusks using 87Sr/ 86Sr analyses: Evaluation of kinetic models and estimation of regional Late Pleistocene temperature history</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Wehmiller, J.F.; Harris, W.B.; Boutin, B.S.; Farrell, K.M.</p> <p>2012-01-01</p> <p>The use of amino acid racemization (AAR) for estimating ages of Quaternary fossils usually requires a combination of kinetic and effective temperature modeling or independent age calibration of analyzed samples. Because of limited availability of calibration samples, age estimates are often based on model extrapolations from single calibration points over wide ranges of D/L values. Here we present paired AAR and 87Sr/ 86Sr results for Pleistocene mollusks from the North Carolina Coastal Plain, USA. 87Sr/ 86Sr age estimates, derived from the lookup table of McArthur et al. [McArthur, J.M., Howarth, R.J., Bailey, T.R., 2001. Strontium isotopic stratigraphy: LOWESS version 3: best fit to the marine Sr-isotopic curve for 0-509 Ma and accompanying Look-up table for deriving numerical age. Journal of Geology 109, 155-169], provide independent age calibration over the full range of amino acid D/L values, thereby allowing comparisons of alternative kinetic models for seven amino acids. The often-used parabolic kinetic model is found to be insufficient to explain the pattern of racemization, although the kinetic pathways for valine racemization and isoleucine epimerization can be closely approximated with this function. Logarithmic and power law regressions more accurately represent the racemization pathways for all amino acids. The reliability of a non-linear model for leucine racemization, developed and refined over the past 20 years, is confirmed by the 87Sr/ 86Sr age results. This age model indicates that the subsurface record (up to 80m thick) of the North Carolina Coastal Plain spans the entire Quaternary, back to ???2.5Ma. The calibrated kinetics derived from this age model yield an estimate of the effective temperature for the study region of 11??2??C., from which we estimate full glacial (Last Glacial Maximum - LGM) temperatures for the region on the order of 7-10??C cooler than present. These temperatures compare favorably with independent paleoclimate information for the region. ?? 2011 Elsevier B.V.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2008AGUFMDI53A1679W','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2008AGUFMDI53A1679W"><span>An Evaluation of the Fixed Hotspot Hypothesis for the Pacific Plate</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Wessel, P.; Kroenke, L. W.</p> <p>2008-12-01</p> <p>Using geometry and ages from 12 Pacific seamount chains, we recently constructed two new Pacific absolute plate motion models that extend our self-consistent and high-resolution models back to 145 Ma. The WK08-A model maps the full uncertainty in the age progressions into uncertainties in rotation opening angles, yielding a relatively smooth plate motion model. The WK08-G model relaxes the mapping of age uncertainties in order to better isolate secondary geometry changes seen along many co-registered chains. Both models have been used to assess the viability of the fixed hotspot hypothesis in the Pacific. In constructing these models, we found that only a small group of age samples had to be discarded on the grounds that they were discordant with the dominant trends. We were able to connect plate motions for pre- and post-Emperor age intervals by including the Ratak-Gilbert-Ellice, Liliuokalani and Musicians trails in our analysis. However, as no active hotspot locations exist for the older chains their inclusion adds additional model parameters. Both age and geometry misfits increase with age, reflecting the observed increase in age uncertainties and the broader and less distinct nature of the older trails. Paleomagnetic observations from the Emperor seamount chain have been interpreted to suggest that these seamounts must have formed at latitudes significantly more northerly than the present location of the Hawaii hotspot, implying a drifting mantle plume. At the same time, new estimates of the age of the Hawaii- Emperor bend places bend formation at a time of global plate reorganization. We will present a complete analysis of inter-chain distances between coeval radiometric samples from Pacific chains and compare these distances to the inter-hotspot distances at the present time. Significant departures from the current hotspot separations would be direct and unequivocal evidence of motion between the Pacific hotspot reference frame and the spin axis and as such complement the paleomagnetic analysis. Preliminary results suggest the Emperor segment data may indicate an increase in hotspot separation.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25450787','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25450787"><span>Examination of DNA methylation status of the ELOVL2 marker may be useful for human age prediction in forensic science.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Zbieć-Piekarska, Renata; Spólnicka, Magdalena; Kupiec, Tomasz; Makowska, Żanetta; Spas, Anna; Parys-Proszek, Agnieszka; Kucharczyk, Krzysztof; Płoski, Rafał; Branicki, Wojciech</p> <p>2015-01-01</p> <p>Age estimation in forensic investigations may complement the prediction of externally visible characteristics and the inference of biogeographical ancestry, thus allowing a better description of an unknown individual. Multiple CpG sites that show linear correlation between age and degree of DNA methylation have been identified in the human genome, providing a selection of candidates for age prediction. In this study, we optimized an assay based on bisulfite conversion and pyrosequencing of 7 CpG sites located in the ELOVL2 gene. Examination of 303 blood samples collected from individuals aged 2-75 years allowed selection of the most informative site, explaining 83% of variation in age. The final linear regression model included two CpG sites in ELOVL2 and enabled age prediction with R(2)=0.859, prediction error=6.85 and mean absolute deviation MAD=5.03. Examination of a testing set of 124 blood samples (MAD=5.75) showed that 68.5% of samples were correctly predicted, assuming that chronological and predicted ages matched ± 7 years. It was found that the ELOVL2 methylation status in bloodstains had not changed significantly after 4 weeks of storage in room temperature conditions. Analysis of 45 bloodstains deposited on tissue paper after 5, 10 and 15 years of storage in room conditions indicated that although a gradual decrease of positive PCR results was observed, the general age prediction success rate remained similar and equaled 60-78%. The obtained results show that the ELOVL2 locus provides a very good source of information about human chronological age based on analysis of blood, including bloodstains, and it may constitute a powerful and reliable predictor in future forensic age estimation models. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24022910','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24022910"><span>Cross cultural analysis of factors associated with age at natural menopause among Latin-American immigrants to Madrid and their Spanish neighbors.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Pérez-Alcalá, Irene; Sievert, Lynnette Leidy; Obermeyer, Carla Makhlouf; Reher, David Sven</p> <p>2013-01-01</p> <p>In this study, age at menopause was examined in relation to demographic and life style factors among Latin-American immigrants to Madrid and their Spanish counterparts. Respondents were drawn from the Decisions at Menopause Study (2002-2003) and from a recent sample of Latin-American immigrants to Madrid (2010-2011). The final sample included 484 women after excluding women with induced menopause and use of HT. Probit analyses and Cox proportional hazard models were used to estimate median age at menopause and to identify factors associated with an early age at menopause. Median estimated age at natural menopause was 52.0 years (51.2-53.0) for Spanish women and 50.5 years (49.9-51.2) for Latin-American women. Immigrant women were more likely to reach menopause at an earlier age after controlling for confounding factors. Nulliparity and lower levels of education were associated with an earlier age at menopause. A higher body mass index was associated with a later age at menopause in the Spanish model. Among the Latin-American sample, women from the Dominican Republic and women who underwent menopause before migrating were more likely to reach menopause at an earlier age. The results reported here demonstrate that early life events, including place of birth, and later life events, such as timing of migration, were associated with age at menopause. This study highlights the importance of taking into account differences in the age of onset of menopause in the multicultural population of Madrid when considering the health of women at midlife and beyond. Copyright © 2013 Wiley Periodicals, Inc.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26866794','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26866794"><span>Age-related invariance of abilities measured with the Wechsler Adult Intelligence Scale-IV.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sudarshan, Navaneetham J; Bowden, Stephen C; Saklofske, Donald H; Weiss, Lawrence G</p> <p>2016-11-01</p> <p>Assessment of measurement invariance across populations is essential for meaningful comparison of test scores, and is especially relevant where repeated measurements are required for educational assessment or clinical diagnosis. Establishing measurement invariance legitimizes the assumption that test scores reflect the same psychological trait in different populations or across different occasions. Examination of Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) U.S. standardization samples revealed that a first-order 5-factor measurement model was best fitting across 9 age groups from 16 years to 69 years. Strong metric invariance was found for 3 of 5 factors and partial intercept invariance for the remaining 2. Pairwise comparisons of adjacent age groups supported the inference that cognitive-trait group differences are manifested by group differences in the test scores. In educational and clinical settings these findings provide theoretical and empirical support to interpret changes in the index or subtest scores as reflecting changes in the corresponding cognitive abilities. Further, where clinically relevant, the subtest score composites can be used to compare changes in respective cognitive abilities. The model was supported in the Canadian standardization data with pooled age groups but the sample sizes were not adequate for detailed examination of separate age groups in the Canadian sample. (PsycINFO Database Record (c) 2016 APA, all rights reserved).</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29912439','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29912439"><span>Do age and gender contribute to workers' burnout symptoms?</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Marchand, A; Blanc, M-E; Beauregard, N</p> <p>2018-06-15</p> <p>Despite mounting evidence on the association between work stress and burnout, there is limited knowledge about the extent to which workers' age and gender are associated with burnout. To evaluate the relationship between age, gender and their interaction with burnout in a sample of Canadian workers. Data were collected in 2009-12 from a sample of 2073 Canadian workers from 63 workplaces in the province of Quebec. Data were analysed with multilevel regression models to test for linear and non-linear relationships between age and burnout. Analyses adjusted for marital status, parental status, educational level and number of working hours were conducted on the total sample and stratified by gender. Data were collected from a sample of 2073 Canadian workers (response rate 73%). Age followed a non-linear relationship with emotional exhaustion and total burnout, while it was linearly related to cynicism and reduced professional efficacy. Burnout level reduced with increasing age in men, but the association was bimodal in women, with women aged between 20-35 and over 55 years showing the highest burnout level. These results suggest that burnout symptoms varied greatly according to different life stages of working men and women. Younger men, and women aged between 20-35 and 55 years and over are particularly susceptible and should be targeted for programmes to reduce risk of burnout.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/10418169','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/10418169"><span>Strontium-90 concentration measurements in human bones and teeth in Greece.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Stamoulis, K C; Assimakopoulos, P A; Ioannides, K G; Johnson, E; Soucacos, P N</p> <p>1999-05-19</p> <p>Strontium-90 concentration was measured in human bones and teeth collected in Greece during the period 1992-1996. One hundred and five bone samples, mainly cancellous bone, and 108 samples, taken from a total of 896 individual teeth were processed. Samples were classified according to the age and sex of the donors. Samples were chemically pre-treated according to a specially devised method to enable extraction of 90Y, at equilibrium with 90Sr in the original sample. Subsequently, 90Y beta activity was measured with a gas proportional counter. Radiostrontium concentration in bone samples showed small variations with respect to age or sex, with an average value of 30 mBq 90Sr/g Ca. However, 90Sr concentration measurements in teeth demonstrated a pronounced structure, which clearly reflects contamination from the 1960s atmospheric nuclear weapons tests and the more recent Chernobyl accident. This difference is attributed to the different histological structure of skeletal bones and teeth, the later consisting mainly of compact bone. An age-dependent model for radiostrontium concentration in human bones and teeth is developed which is able to successfully reproduce the experimental data. Through a fitting process, the model also yielded calcium turnover rates for compact bone, as a function of age, as well as an estimate of radiostrontium contamination of foodstuffs in Greece for the past four decades. The results obtained in this study indicate that radiostrontium environmental contamination which resulted from the atmospheric nuclear weapons tests in the 1960s, exceed by far that caused by the Chernobyl accident.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li class="active"><span>7</span></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_7 --> <div id="page_8" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li class="active"><span>8</span></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="141"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25642206','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25642206"><span>Cognitive aging on latent constructs for visual processing capacity: a novel structural equation modeling framework with causal assumptions based on a theory of visual attention.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Nielsen, Simon; Wilms, L Inge</p> <p>2014-01-01</p> <p>We examined the effects of normal aging on visual cognition in a sample of 112 healthy adults aged 60-75. A testbattery was designed to capture high-level measures of visual working memory and low-level measures of visuospatial attention and memory. To answer questions of how cognitive aging affects specific aspects of visual processing capacity, we used confirmatory factor analyses in Structural Equation Modeling (SEM; Model 2), informed by functional structures that were modeled with path analyses in SEM (Model 1). The results show that aging effects were selective to measures of visual processing speed compared to visual short-term memory (VSTM) capacity (Model 2). These results are consistent with some studies reporting selective aging effects on processing speed, and inconsistent with other studies reporting aging effects on both processing speed and VSTM capacity. In the discussion we argue that this discrepancy may be mediated by differences in age ranges, and variables of demography. The study demonstrates that SEM is a sensitive method to detect cognitive aging effects even within a narrow age-range, and a useful approach to structure the relationships between measured variables, and the cognitive functional foundation they supposedly represent.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.fs.usda.gov/treesearch/pubs/37730','TREESEARCH'); return false;" href="https://www.fs.usda.gov/treesearch/pubs/37730"><span>Implications of alternative field-sampling designs on Landsat-based mapping of stand age and carbon stocks in Oregon forests</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.fs.usda.gov/treesearch/">Treesearch</a></p> <p>Maureen V. Duane; Warren B. Cohen; John L. Campbell; Tara Hudiburg; David P. Turner; Dale Weyermann</p> <p>2010-01-01</p> <p>Empirical models relating forest attributes to remotely sensed metrics are widespread in the literature and underpin many of our efforts to map forest structure across complex landscapes. In this study we compared empirical models relating Landsat reflectance to forest age across Oregon using two alternate sets of ground data: one from a large (n ~ 1500) systematic...</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=parenting+AND+style+AND+self+AND+control&pg=6&id=EJ861718','ERIC'); return false;" href="https://eric.ed.gov/?q=parenting+AND+style+AND+self+AND+control&pg=6&id=EJ861718"><span>Parenting and Antisocial Behavior: A Model of the Relationship between Adolescent Self-Disclosure, Parental Closeness, Parental Control, and Adolescent Antisocial Behavior</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Vieno, Alessio; Nation, Maury; Pastore, Massimiliano; Santinello, Massimo</p> <p>2009-01-01</p> <p>This study used data collected from a sample of 840 Italian adolescents (418 boys; M age = 12.58) and their parents (657 mothers; M age = 43.78) to explore the relations between parenting, adolescent self-disclosure, and antisocial behavior. In the hypothesized model, parenting practices (e.g., parental monitoring and control) have direct effects…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JHyd..547..332D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JHyd..547..332D"><span>The impact of green roof ageing on substrate characteristics and hydrological performance</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>De-Ville, Simon; Menon, Manoj; Jia, Xiaodong; Reed, George; Stovin, Virginia</p> <p>2017-04-01</p> <p>Green roofs contribute to stormwater management through the retention of rainfall and the detention of runoff. However, there is very limited knowledge concerning the evolution of green roof hydrological performance with system age. This study presents a non-invasive technique which allows for repeatable determination of key substrate characteristics over time, and evaluates the impact of observed substrate changes on hydrological performance. The physical properties of 12 green roof substrate cores have been evaluated using non-invasive X-ray microtomography (XMT) imaging. The cores comprised three replicates of two contrasting substrate types at two different ages: unused virgin samples; and 5-year-old samples from existing green roof test beds. Whilst significant structural differences (density, pore and particle sizes, tortuosity) between virgin and aged samples of a crushed brick substrate were observed, these differences did not significantly affect hydrological characteristics (maximum water holding capacity and saturated hydraulic conductivity). A contrasting substrate based upon a light expanded clay aggregate experienced increases in the number of fine particles and pores over time, which led to increases in maximum water holding capacity of 7%. In both substrates, the saturated hydraulic conductivity estimated from the XMT images was lower in aged compared with virgin samples. Comparisons between physically-derived and XMT-derived substrate hydrological properties showed that similar values and trends in the data were identified, confirming the suitability of the non-invasive XMT technique for monitoring changes in engineered substrates over time. The observed effects of ageing on hydrological performance were modelled as two distinct hydrological processes, retention and detention. Retention performance was determined via a moisture-flux model using physically-derived values of virgin and aged maximum water holding capacity. Increased water holding capacity with age increases the potential for retention performance. However, seasonal variations in retention performance greatly exceed those associated with the observed age-related increases in water holding capacity (+72% vs +7% respectively). Detention performance was determined via an unsaturated-flow finite element model, using van Genuchten parameters and XMT-derived values of saturated hydraulic conductivity. Reduced saturated hydraulic conductivity increases detention performance. For a 1-hour 30-year design storm, the peak runoff was found to be 33% lower for the aged brick-based substrate compared with its virgin counterpart.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4058367','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4058367"><span>Moderating the Covariance Between Family Member’s Substance Use Behavior</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Eaves, Lindon J.; Neale, Michael C.</p> <p>2014-01-01</p> <p>Twin and family studies implicitly assume that the covariation between family members remains constant across differences in age between the members of the family. However, age-specificity in gene expression for shared environmental factors could generate higher correlations between family members who are more similar in age. Cohort effects (cohort × genotype or cohort × common environment) could have the same effects, and both potentially reduce effect sizes estimated in genome-wide association studies where the subjects are heterogeneous in age. In this paper we describe a model in which the covariance between twins and non-twin siblings is moderated as a function of age difference. We describe the details of the model and simulate data using a variety of different parameter values to demonstrate that model fitting returns unbiased parameter estimates. Power analyses are then conducted to estimate the sample sizes required to detect the effects of moderation in a design of twins and siblings. Finally, the model is applied to data on cigarette smoking. We find that (1) the model effectively recovers the simulated parameters, (2) the power is relatively low and therefore requires large sample sizes before small to moderate effect sizes can be found reliably, and (3) the genetic covariance between siblings for smoking behavior decays very rapidly. Result 3 implies that, e.g., genome-wide studies of smoking behavior that use individuals assessed at different ages, or belonging to different birth-year cohorts may have had substantially reduced power to detect effects of genotype on cigarette use. It also implies that significant special twin environmental effects can be explained by age-moderation in some cases. This effect likely contributes to the missing heritability paradox. PMID:24647834</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AGUFM.T22E..06B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AGUFM.T22E..06B"><span>Inception and Early Evolution of the Aleutian Arc</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Bezard, R.; Hoernle, K.; Hauff, F.; Portnyagin, M.; Werner, R.; Yogodzinski, G.; Jicha, B.; Garbe-Schönberg, D.; Turner, S.; Schaefer, B. F.</p> <p>2017-12-01</p> <p>Constraining the timing and style of subduction initiation in the Aleutian system is critical to model the Cenozoic geodynamic evolution of the Pacific. Until now, the oldest ages for the Aleutian arc suggest a subduction inception at c.a. 46-47 Ma. However, the compositions of these samples (arc tholeiites and calc-alkaline rocks) are different from those of typical early-arc sequences found at extensively studied subduction systems (Izu-Bonin-Mariana), dominated by FABs and boninites. Thus, if the FAB/boninite model applies to the Aleutian, the oldest units might not have been recovered yet and the arc inception could have occurred earlier than 47 Ma. To test this hypothesis, we have sampled the lowermost submarine Aleutian sequences at ten forearc and rear-arc localities during the R/V SONNE Cruise 249. We present preliminary whole-rock major and trace element concentrations, Sr-Nd-Hf-Pb isotopes as well as U-Pb zircon dating on the recovered igneous rocks. The sample compositions range from tholeiitic to calc-alkaline. No boninites were found. Most of the samples show strong subduction signatures. However, the remaining rocks present no or minor arc-type trace element features. These samples are either depleted tholeiites with similar trace element characteristics to FABs or enriched calc-alkaline rocks. Preliminary zircon dating suggests an age of 47.2 ± 1.2 Ma for one of the samples with strong arc signatures, consistent with the oldest published ages for the Aleutian so far. However, based on their compositional similarities to FABs, the depleted tholeiites should be older than the arc-type rocks, suggesting that subduction initiation could have occurred earlier than the above-mentioned age. The absence of boninite could either reflect an incomplete sampling of the early-arc sequences or a different initiation style compared to other Pacific subduction zones. Further ages and radiogenic isotope data should refine these interpretations.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18189239','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18189239"><span>A genomic scan for age at onset of Alzheimer's disease in 437 families from the NIMH Genetic Initiative.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Dickson, M Ryan; Li, Jian; Wiener, Howard W; Perry, Rodney T; Blacker, Deborah; Bassett, Susan S; Go, Rodney C P</p> <p>2008-09-05</p> <p>We performed linkage analysis for age at onset (AAO) in the total Alzheimer's disease (AD) NIMH sample (N = 437 families). Families were subset as late-onset (320 families, AAO > or = 65) and early/mixed (117 families, at least 1 member with 50 < AAO < 65). Treating AAO as a censored trait, we obtained the gender and APOE adjusted residuals in a parametric survival model and analyzed the residuals as the quantitative trait (QT) in variance-component linkage analysis. For comparison, AAO-age at exam (AAE) was analyzed as the QT adjusting for affection status, gender, and APOE. Heritabilities for residual and AAO-AAE outcomes were 66.3% and 74.0%, respectively for the total sample, 56.0% and 57.0% in the late-onset sample, and 33.0% for both models in the early/mixed sample. The residual model yielded the largest peaks on chromosome 1 with LOD = 2.0 at 190 cM in the total set, LOD = 1.7 at 116 cM on chromosome 3 in the early/mixed subset, and LOD = 1.4 at 71 and 86 cM, respectively, on chromosome 6 in the late-onset subset. For the AAO-AAE outcome model the largest peaks were identified on chromosome 1 at 137 cM (LOD = 2.8) and chromosome 6 at 69 cM (LOD = 2.3) and 86 cM (LOD = 2.2) all in the late-onset subset. Additional peaks with LOD > or = 1 were identified on chromosomes 1, 2, 3, 6, 8, 9, 10, and 12 for the total sample and each subset. Results replicate previous findings, but identify additional suggestive peaks indicating the genetics of AAO in AD is complex with many chromosomal regions potentially containing modifying genes. 2008 Wiley-Liss, Inc.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27857017','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27857017"><span>[The Influence of Subjective Health Status, Post-Traumatic Growth, and Social Support on Successful Aging in Middle-Aged Women].</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lee, Seung Hee; Jang, Hyung Suk; Yang, Young Hee</p> <p>2016-10-01</p> <p>This study was done to investigate factors influencing successful aging in middle-aged women. A convenience sample of 103 middle-aged women was selected from the community. Data were collected using a structured questionnaire and analyzed using descriptive statistics, two-sample t-test, one-way ANOVA, Kruskal Wallis test, Pearson correlations, Spearman correlations and multiple regression analysis with the SPSS/WIN 22.0 program. Results of regression analysis showed that significant factors influencing successful aging were post-traumatic growth and social support. This regression model explained 48% of the variance in successful aging. Findings show that the concept 'post-traumatic growth' is an important factor influencing successful aging in middle-aged women. In addition, social support from friends/co-workers had greater influence on successful aging than social support from family. Thus, we need to consider the positive impact of post-traumatic growth and increase the chances of social participation in a successful aging program for middle-aged women.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5865564','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5865564"><span>Biological age as a health index for mortality and major age-related disease incidence in Koreans: National Health Insurance Service – Health screening 11-year follow-up study</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Kang, Young Gon; Suh, Eunkyung; Lee, Jae-woo; Kim, Dong Wook; Cho, Kyung Hee; Bae, Chul-Young</p> <p>2018-01-01</p> <p>Purpose A comprehensive health index is needed to measure an individual’s overall health and aging status and predict the risk of death and age-related disease incidence, and evaluate the effect of a health management program. The purpose of this study is to demonstrate the validity of estimated biological age (BA) in relation to all-cause mortality and age-related disease incidence based on National Sample Cohort database. Patients and methods This study was based on National Sample Cohort database of the National Health Insurance Service – Eligibility database and the National Health Insurance Service – Medical and Health Examination database of the year 2002 through 2013. BA model was developed based on the National Health Insurance Service – National Sample Cohort (NHIS – NSC) database and Cox proportional hazard analysis was done for mortality and major age-related disease incidence. Results For every 1 year increase of the calculated BA and chronological age difference, the hazard ratio for mortality significantly increased by 1.6% (1.5% in men and 2.0% in women) and also for hypertension, diabetes mellitus, heart disease, stroke, and cancer incidence by 2.5%, 4.2%, 1.3%, 1.6%, and 0.4%, respectively (p<0.001). Conclusion Estimated BA by the developed BA model based on NHIS – NSC database is expected to be used not only as an index for assessing health and aging status and predicting mortality and major age-related disease incidence, but can also be applied to various health care fields. PMID:29593385</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=222544&Lab=NRMRL&keyword=malachite&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50','EPA-EIMS'); return false;" href="https://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=222544&Lab=NRMRL&keyword=malachite&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50"><span>Impact of Plumbing Age on Copper Levels in Drinking Water</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://oaspub.epa.gov/eims/query.page">EPA Science Inventory</a></p> <p></p> <p></p> <p>Theory and limited practical experiences suggest that higher copper levels in drinking water tap samples are typically associated with newer plumbing systems, and levels decrease with increasing plumbing age. Past researchers have developed a conceptual model to explain the “agin...</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AGUFM.C11B0905S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AGUFM.C11B0905S"><span>3D Modeling of Glacial Erratic Boulders in the Haizi Shan Region, Eastern Tibetan Plateau</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sheriff, M.; Stevens, J.; Radue, M. J.; Strand, P.; Zhou, W.; Putnam, A. E.</p> <p>2017-12-01</p> <p>The focus of our team's research is to study patterns of glacier retreat in the Northern and Southern Hemispheres at the end of the last ice age. Our purpose is to search for what caused this great global warming. Such information will improve understanding of how the climate system may respond to the human-induced buildup of fossil carbon dioxide. To reconstruct past glacier behavior, we sample boulders deposited by glaciers to find the rate of ancient recession. Each sample is tested to determine the age of the boulder using 10Be cosmogenic-nuclide dating. My portion of this research focuses on creating 3D models of the sampled boulders. Such high-resolution 3D models afford visual inspection and analysis of each boulder in a virtual reality environment after fieldwork is complete. Such detailed virtual reconstructions will aid post-fieldwork evaluation of sampled boulders. This will help our team interpret 10Be dating results. For example, a high-resolution model can aid post-fieldwork observations, and allow scientists to determine whether the rock has been previously covered, eroded, or moved since it was deposited by the glacier, but before the sample was collected. Also a model can be useful for recognizing patterns between age and boulder morphology. Lastly, the models can be used for those who wish to review the data after publication. To create the 3D models, I will use Hero4 GoPro and Canon PowerShot digital cameras to collect photographs of each boulder from different angles. I will then process the digital imagery using `structure-from-motion' techniques and Agisoft Photoscan software. All boulder photographs will be synthesized to 3D and based on a standardized scale. We will then import these models into an environment that can be accessed using cutting-edge virtual reality technology. By producing a virtual archive of 3D glacial boulder reconstructions, I hope to provide deeper insight into geological processes influencing these boulders during and since their deposition, and ultimately to improve methods that are being used to develop glacial histories on a global scale.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26731122','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26731122"><span>Bifactor Models Show a Superior Model Fit: Examination of the Factorial Validity of Parent-Reported and Self-Reported Symptoms of Attention-Deficit/Hyperactivity Disorders in Children and Adolescents.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Rodenacker, Klaas; Hautmann, Christopher; Görtz-Dorten, Anja; Döpfner, Manfred</p> <p>2016-01-01</p> <p>Various studies have demonstrated that bifactor models yield better solutions than models with correlated factors. However, the kind of bifactor model that is most appropriate is yet to be examined. The current study is the first to test bifactor models across the full age range (11-18 years) of adolescents using self-reports, and the first to test bifactor models with German subjects and German questionnaires. The study sample included children and adolescents aged between 6 and 18 years recruited from a German clinical sample (n = 1,081) and a German community sample (n = 642). To examine the factorial validity, we compared unidimensional, correlated factors and higher-order and bifactor models and further tested a modified incomplete bifactor model for measurement invariance. Bifactor models displayed superior model fit statistics compared to correlated factor models or second-order models. However, a more parsimonious incomplete bifactor model with only 2 specific factors (inattention and impulsivity) showed a good model fit and a better factor structure than the other bifactor models. Scalar measurement invariance was given in most group comparisons. An incomplete bifactor model would suggest that the specific inattention and impulsivity factors represent entities separable from the general attention-deficit/hyperactivity disorder construct and might, therefore, give way to a new approach to subtyping of children beyond and above attention-deficit/hyperactivity disorder. © 2016 S. Karger AG, Basel.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010MNRAS.403..797G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010MNRAS.403..797G"><span>Testing spectral models for stellar populations with star clusters - II. Results</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>González Delgado, Rosa M.; Cid Fernandes, Roberto</p> <p>2010-04-01</p> <p>High spectral resolution evolutionary synthesis models have become a routinely used ingredient in extragalactic work, and as such deserve thorough testing. Star clusters are ideal laboratories for such tests. This paper applies the spectral fitting methodology outlined in Paper I to a sample of clusters, mainly from the Magellanic Clouds and spanning a wide range in age and metallicity, fitting their integrated light spectra with a suite of modern evolutionary synthesis models for single stellar populations. The combinations of model plus spectral library employed in this investigation are Galaxev/STELIB, Vazdekis/MILES, SED@/GRANADA and Galaxev/MILES+GRANADA, which provide a representative sample of models currently available for spectral fitting work. A series of empirical tests are performed with these models, comparing the quality of the spectral fits and the values of age, metallicity and extinction obtained with each of them. A comparison is also made between the properties derived from these spectral fits and literature data on these nearby, well studied clusters. These comparisons are done with the general goal of providing useful feedback for model makers, as well as guidance to the users of such models. We find the following. (i) All models are able to derive ages that are in good agreement both with each other and with literature data, although ages derived from spectral fits are on average slightly older than those based on the S-colour-magnitude diagram (S-CMD) method as calibrated by Girardi et al. (ii) There is less agreement between the models for the metallicity and extinction. In particular, Galaxev/STELIB models underestimate the metallicity by ~0.6 dex, and the extinction is overestimated by 0.1 mag. (iii) New generations of models using the GRANADA and MILES libraries are superior to STELIB-based models both in terms of spectral fit quality and regarding the accuracy with which age and metallicity are retrieved. Accuracies of about 0.1 dex in age and 0.3 dex in metallicity can be achieved as long as the models are not extrapolated beyond their expected range of validity.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016GeCoA.192..166H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016GeCoA.192..166H"><span>Cross-checking groundwater age by 4He and 14C dating in a granite, Tono area, central Japan</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Hasegawa, Takuma; Nakata, Kotaro; Tomioka, Yuichi; Goto, Kazuyuki; Kashiwaya, Koki; Hama, Katsuhiro; Iwatsuki, Teruki; Kunimaru, Takanori; Takeda, Masaki</p> <p>2016-11-01</p> <p>Groundwater dating was performed simultaneously by the 4He and 14C methods in granite of the Tono area in central Japan. Groundwater was sampled at 30 packed-off sections of six 1000-m boreholes. 4He concentrations increased and 14C concentrations decreased along a groundwater flow path on a topographic gradient. 4He ages were calculated by using the in situ 4He production rate derived from the porosity, density, and U and Th content of the rock, neglecting external flux. 14C ages were calculated with a noncorrected model in which the initial 14C content was 100 percent of the modern radiocarbon level (Co = 100 pmC), a statistical model using the average 14C content of tritium-bearing samples (Co = 46.4 pmC), and a δ13C model based on the isotopic mass balance. Although the absolute 14C ages calculated by the models were different, the relative 14C ages were almost identical. The relative 14C ages were considered reliable because dissolved inorganic carbon has no significant geochemical reactions in granite. The relation between the 4He ages and the noncorrected 14C ages was [4He age] = 1.15 [14C age] + 7200 (R2 = 0.81), except in the discharge area. The slope of this relation was equivalent to unity, which indicates that the 4He accumulation rate is confirmed by the relative 14C ages. Moreover, the accumulated 3He/4He ratio was equivalent to that derived from the 6Li(α,n)3H reaction in granite. These results show that the accumulated He is of crustal origin, produced in situ without external flux, except in the discharge area. The intercept value of 7200 a implies that the 14C concentrations were diluted due to geochemical reactions. Tritium-bearing samples supported this result. Simultaneous measurements make it feasible to estimate the accumulation rate of 4He and initial dilution of 14C, which cannot be done with a single method. Cross-checking groundwater dating has the potential to provide more reliable groundwater ages. The circulation time of the groundwater flow in the Tono area may be several tens of thousands of years, and the groundwater age calculated from the 4He and 14C ages appears to be consistent with geochemical information such as groundwater types, δD and δ18O.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24727429','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24727429"><span>Isolation and identification of age-related DNA methylation markers for forensic age-prediction.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Yi, Shao Hua; Xu, Long Chang; Mei, Kun; Yang, Rong Zhi; Huang, Dai Xin</p> <p>2014-07-01</p> <p>Age-prediction is an important part of forensic science. There is no available method of individual age-prediction for general forensic biological samples at crime scenes. Accumulating evidence indicates that aging resembles a developmentally regulated process tightly controlled by specific age-associated methylation exists in human genome. This study isolated and identified eight gene fragments in which the degree of cytosine methylation is significantly correlated with age in blood of 40 donors. Furthermore, we validated two CpG sites of each gene fragment and replicated our results in a general population sample of 40 males and 25 females with a wide age-range (11-72 years). The methylation of these fragments is linear with age over a range of six decades (Fragment P1 (r=-0.64), P2 (r=-0.58), P3 (r=-0.79), R1 (r=0.82), R2 (r=0.63), R3 (r=0.59), R4 (r=0.63) and R5 (r=0.62)). Using average methylation of two CpG sites from each fragment, we built a regression model that explained 95% of the variance in age and is able to predict the age of an individual with great accuracy (R(2)=0.918). The predicted values are highly correlated with the observed age in the sample (r=0.91). This study implicates that DNA methylation will be an available biological marker of age-prediction. Furthermore, measurement of relevant sites in the genome could be a tool in routine forensic screening to predict age of biological samples. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=functional+AND+regression+AND+models&pg=7&id=EJ696455','ERIC'); return false;" href="https://eric.ed.gov/?q=functional+AND+regression+AND+models&pg=7&id=EJ696455"><span>An Integrational Model of Quality of Life in Older Age. Results from the Esrc/mrc Hsrc Quality of Life Survey in Britain.(author Abstract)</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Bowling, Ann; Gabriel, Zahava</p> <p>2004-01-01</p> <p>This paper is based on the results of a national survey of the quality of life of 999 randomly sampled people aged 65 and over, living at home in Britain. The survey was semi-structured, and a sample of survey respondents was followed up and interviewed in-depth in order to explore their perceptions of quality of life in full. Comparisons are made…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29332693','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29332693"><span>Ink dating part II: Interpretation of results in a legal perspective.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Koenig, Agnès; Weyermann, Céline</p> <p>2018-01-01</p> <p>The development of an ink dating method requires an important investment of resources in order to step from the monitoring of ink ageing on paper to the determination of the actual age of a questioned ink entry. This article aimed at developing and evaluating the potential of three interpretation models to date ink entries in a legal perspective: (1) the threshold model comparing analytical results to tabulated values in order to determine the maximal possible age of an ink entry, (2) the trend tests that focusing on the "ageing status" of an ink entry, and (3) the likelihood ratio calculation comparing the probabilities to observe the results under at least two alternative hypotheses. This is the first report showing ink dating interpretation results on a ballpoint be ink reference population. In the first part of this paper three ageing parameters were selected as promising from the population of 25 ink entries aged during 4 to 304days: the quantity of phenoxyethanol (PE), the difference between the PE quantities contained in a naturally aged sample and an artificially aged sample (R NORM ) and the solvent loss ratio (R%). In the current part, each model was tested using the three selected ageing parameters. Results showed that threshold definition remains a simple model easily applicable in practice, but that the risk of false positive cannot be completely avoided without reducing significantly the feasibility of the ink dating approaches. The trend tests from the literature showed unreliable results and an alternative had to be developed yielding encouraging results. The likelihood ratio calculation introduced a degree of certainty to the ink dating conclusion in comparison to the threshold approach. The proposed model remains quite simple to apply in practice, but should be further developed in order to yield reliable results in practice. Copyright © 2017 The Chartered Society of Forensic Sciences. Published by Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JEI....26e3011L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JEI....26e3011L"><span>Face aging effect simulation model based on multilayer representation and shearlet transform</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Li, Yuancheng; Li, Yan</p> <p>2017-09-01</p> <p>In order to extract detailed facial features, we build a face aging effect simulation model based on multilayer representation and shearlet transform. The face is divided into three layers: the global layer of the face, the local features layer, and texture layer, which separately establishes the aging model. First, the training samples are classified according to different age groups, and we use active appearance model (AAM) at the global level to obtain facial features. The regression equations of shape and texture with age are obtained by fitting the support vector machine regression, which is based on the radial basis function. We use AAM to simulate the aging of facial organs. Then, for the texture detail layer, we acquire the significant high-frequency characteristic components of the face by using the multiscale shearlet transform. Finally, we get the last simulated aging images of the human face by the fusion algorithm. Experiments are carried out on the FG-NET dataset, and the experimental results show that the simulated face images have less differences from the original image and have a good face aging simulation effect.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24466773','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24466773"><span>[Stature estimation for Sichuan Han nationality female based on X-ray technology with measurement of lumbar vertebrae].</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Qing, Si-han; Chang, Yun-feng; Dong, Xiao-ai; Li, Yuan; Chen, Xiao-gang; Shu, Yong-kang; Deng, Zhen-hua</p> <p>2013-10-01</p> <p>To establish the mathematical models of stature estimation for Sichuan Han female with measurement of lumbar vertebrae by X-ray to provide essential data for forensic anthropology research. The samples, 206 Sichuan Han females, were divided into three groups including group A, B and C according to the ages. Group A (206 samples) consisted of all ages, group B (116 samples) were 20-45 years old and 90 samples over 45 years old were group C. All the samples were examined lumbar vertebrae through CR technology, including the parameters of five centrums (L1-L5) as anterior border, posterior border and central heights (x1-x15), total central height of lumbar spine (x16), and the real height of every sample. The linear regression analysis was produced using the parameters to establish the mathematical models of stature estimation. Sixty-two trained subjects were tested to verify the accuracy of the mathematical models. The established mathematical models by hypothesis test of linear regression equation model were statistically significant (P<0.05). The standard errors of the equation were 2.982-5.004 cm, while correlation coefficients were 0.370-0.779 and multiple correlation coefficients were 0.533-0.834. The return tests of the highest correlation coefficient and multiple correlation coefficient of each group showed that the highest accuracy of the multiple regression equation, y = 100.33 + 1.489 x3 - 0.548 x6 + 0.772 x9 + 0.058 x12 + 0.645 x15, in group A were 80.6% (+/- lSE) and 100% (+/- 2SE). The established mathematical models in this study could be applied for the stature estimation for Sichuan Han females.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29160179','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29160179"><span>The MiAge Calculator: a DNA methylation-based mitotic age calculator of human tissue types.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Youn, Ahrim; Wang, Shuang</p> <p>2018-01-01</p> <p>Cell division is important in human aging and cancer. The estimation of the number of cell divisions (mitotic age) of a given tissue type in individuals is of great interest as it allows not only the study of biological aging (using a new molecular aging target) but also the stratification of prospective cancer risk. Here, we introduce the MiAge Calculator, a mitotic age calculator based on a novel statistical framework, the MiAge model. MiAge is designed to quantitatively estimate mitotic age (total number of lifetime cell divisions) of a tissue using the stochastic replication errors accumulated in the epigenetic inheritance process during cell divisions. With the MiAge model, the MiAge Calculator was built using the training data of DNA methylation measures of 4,020 tumor and adjacent normal tissue samples from eight TCGA cancer types and was tested using the testing data of DNA methylation measures of 2,221 tumor and adjacent normal tissue samples of five other TCGA cancer types. We showed that within each of the thirteen cancer types studied, the estimated mitotic age is universally accelerated in tumor tissues compared to adjacent normal tissues. Across the thirteen cancer types, we showed that worse cancer survivals are associated with more accelerated mitotic age in tumor tissues. Importantly, we demonstrated the utility of mitotic age by showing that the integration of mitotic age and clinical information leads to improved survival prediction in six out of the thirteen cancer types studied. The MiAge Calculator is available at http://www.columbia.edu/∼sw2206/softwares.htm .</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li class="active"><span>8</span></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_8 --> <div id="page_9" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li class="active"><span>9</span></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="161"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18625514','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18625514"><span>A land-use regression model for estimating microenvironmental diesel exposure given multiple addresses from birth through childhood.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ryan, Patrick H; Lemasters, Grace K; Levin, Linda; Burkle, Jeff; Biswas, Pratim; Hu, Shaohua; Grinshpun, Sergey; Reponen, Tiina</p> <p>2008-10-01</p> <p>The Cincinnati Childhood Allergy and Air Pollution Study (CCAAPS) is a prospective birth cohort whose purpose is to determine if exposure to high levels of diesel exhaust particles (DEP) during early childhood increases the risk for developing allergic diseases. In order to estimate exposure to DEP, a land-use regression (LUR) model was developed using geographic data as independent variables and sampled levels of a marker of DEP as the dependent variable. A continuous wind direction variable was also created. The LUR model predicted 74% of the variability in sampled values with four variables: wind direction, length of bus routes within 300 m of the sample site, a measure of truck intensity within 300 m of the sampling site, and elevation. The LUR model was subsequently applied to all locations where the child had spent more than eight hours per week from through age three. A time-weighted average (TWA) microenvironmental exposure estimate was derived for four time periods: 0-6 months, 7-12 months, 13-24 months, 25-36 months. By age two, one third of the children were spending significant time at locations other than home and by 36 months, 39% of the children had changed their residential addresses. The mean cumulative DEP exposure estimate increased from age 6 to 36 months from 70 to 414 microg/m3-days. Findings indicate that using birth addresses to estimate a child's exposure may result in exposure misclassification for some children who spend a significant amount of time at a location with high exposure to DEP.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1976125','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1976125"><span>Modeling the Etiology of Adolescent Substance Use: A Test of the Social Development Model</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Catalano, Richard F.; Kosterman, Rick; Hawkins, J. David; Newcomb, Michael D.; Abbott, Robert D.</p> <p>2007-01-01</p> <p>The social development model is a general theory of human behavior that seeks to explain antisocial behaviors through specification of predictive developmental relationships. It incorporates the effects of empirical predictors (“risk factors” and “protective factors”) for antisocial behavior and attempts to synthesize the most strongly supported propositions of control theory, social learning theory, and differential association theory. This article examines the power of social development model constructs measured at ages 9 to 10 and 13 to 14 to predict drug use at ages 17 to 18. The sample of 590 is from the longitudinal panel of the Seattle Social Development Project, which in 1985 sampled fifth grade students from high crime neighborhoods in Seattle, Washington. Structural equation modeling techniques were used to examine the fit of the model to the data. Although all but one path coefficient were significant and in the expected direction, the model did not fit the data as well as expected (CFI=.87). We next specified second-order factors for each path to capture the substantial common variance in the constructs' opportunities, involvement, and rewards. This model fit the data well (CFI=.90). We conclude that the social development model provides an acceptable fit to predict drug use at ages 17 to 18. Implications for the temporal nature of key constructs and for prevention are discussed. PMID:17848978</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AGUFMEP33C1948H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AGUFMEP33C1948H"><span>Comparison of Cottonwood Dendrochronology and Optically Stimulated Luminescence Geochronometers Along a High Plains Meandering River, Powder River, Montana, USA</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Hasse, T. R.; Schook, D. M.</p> <p>2017-12-01</p> <p>Geochronometers at centennial scales can aid our understanding of process rates in fluvial geomorphology. Plains cottonwood trees (Populus deltoides ssp. Monilifera) in the high plains of the United States are known to germinate on freshly created deposits such as point bars adjacent to rivers. As the trees mature they may be partially buried (up to a few meters) by additional flood deposits. Cottonwood age gives a minimum age estimate of the stratigraphic surface where the tree germinated and a maximum age estimate for overlying sediments, providing quantitative data on rates of river migration and sediment accumulation. Optically Stimulated Luminescence (OSL) of sand grains can be used to estimate the time since the sand grains were last exposed to sunlight, also giving a minimum age estimate of sediment burial. Both methods have disadvantages: Browsing, partial burial, and other damage to young cottonwoods can increase the time required for the tree to reach a height where it can be sampled with a tree corer, making the germination point a few years to a few decades older than the measured tree age; fluvial OSL samples can have inherited age (when the OSL age is older than the burial age) if the sediment was not completely bleached prior to burial. We collected OSL samples at 8 eroding banks of the Powder River Montana, and tree cores at breast height (±1.2 m) from cottonwood trees growing on the floodplain adjacent to the OSL sample locations. Using the Minimum Age Model (MAM) we found that OSL ages appear to be 500 to 1,000 years older than the adjacent cottonwood trees which range in age (at breast height) from 60 to 185 years. Three explanations for this apparent anomaly in ages are explored. Samples for OSL could be below a stratigraphic unconformity relative to the cottonwood germination elevation. Shallow samples for OSL could be affected by anthropogenic mixing of sediments due to plowing and leveling of hay fields. The OSL samples could have significant inherited ages due to partial bleaching during sediment transport in this high plains river with high suspended sediment loads. The dendrochronology of the adjacent cottonwood trees then offers an independent measurement of the inherited age of the OSL samples.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28936139','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28936139"><span>Does active ageing contribute to life satisfaction for older people? Testing a new model of active ageing.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Marsillas, Sara; De Donder, Liesbeth; Kardol, Tinie; van Regenmortel, Sofie; Dury, Sarah; Brosens, Dorien; Smetcoren, An-Sofie; Braña, Teresa; Varela, Jesús</p> <p>2017-09-01</p> <p>Several debates have emerged across the literature about the conceptualisation of active ageing. The aim of this study is to develop a model of the construct that is focused on the individual, including different elements of people's lives that have the potential to be modified by intervention programs. Moreover, the paper examines the contributions of active ageing to life satisfaction, as well as the possible predictive role of coping styles on active ageing. For this purpose, a representative sample of 404 Galician (Spain) community-dwelling older adults (aged ≥60 years) were interviewed using a structured survey. The results demonstrate that the proposed model composed of two broad categories is valid. The model comprises status variables (related to physical, psychological, and social health) as well as different types of activities, called processual variables. This model is tested using partial least squares (PLS) regression. The findings show that active ageing is a fourth-order, formative construct. In addition, PLS analyses indicate that active ageing has a moderate and positive path on life satisfaction and that coping styles may predict active ageing. The discussion highlights the potential of active ageing as a relevant concept for people's lives, drawing out policy implications and suggestions for further research.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21798719','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21798719"><span>Dermal carbonyl modification is related to the yellowish color change of photo-aged Japanese facial skin.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ogura, Yuki; Kuwahara, Tomohiro; Akiyama, Minoru; Tajima, Shingo; Hattori, Kazuhisa; Okamoto, Kouhei; Okawa, Shinpei; Yamada, Yukio; Tagami, Hachiro; Takahashi, Motoji; Hirao, Tetsuji</p> <p>2011-10-01</p> <p>The photo-aged facial skin is characterized by various unique features such as dark spots, wrinkles, and sagging. Elderly people, particularly Asians, tend to show a yellowish skin color change with photo-aging. However, there has been no analytical study conducted on this unique skin color change of the aged facial skin. The purpose of the present study is to examine whether the carbonyl modification in the dermal protein is involved in the yellowish color change that occurs in the photo-aged skin. Normal skin samples excised from the face, abdomen and buttock of variously aged Japanese were separated into the epidermal and the dermal portions. These skin samples were histologically examined for carbonyl modification. Moreover, an in vitro constructed dermis model composed of a contracted collagen gel was treated with acrolein or 4-hydroxynonenal. All these samples were also studied colorimetrically. The dermal samples obtained from the photo-aged facial skin exhibited an appearance of yellowish color, whereas neither the facial epidermis nor the dermis obtained from the abdomen or buttock showed such a yellowish discoloration. The upper layer of the dermis that revealed the yellowish color showed elastosis whose elastic fibers were found to colocalize with carbonyl protein as detected by a labeled hydrazide, as well as by an immunohistochemical examination using the antibody against acrolein adduct. Experimental induction of carbonyl modification in a dermis model in vitro by a long-term treatment with acrolein or 4-hydroxynonenal was found to show the appearance of the yellowish change which was also proven by an increase in b* value of colorimetry. It was more pronounced than that induced by glycation. Our present results strongly suggest that carbonyl modification of the dermal protein is involved in the production of the yellowish color change that is noted in the photo-aged facial skin. Copyright © 2011 Japanese Society for Investigative Dermatology. Published by Elsevier Ireland Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22386121','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22386121"><span>Validating the Student-Teacher Relationship Scale: testing factor structure and measurement invariance across child gender and age in a Dutch sample.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Koomen, Helma M Y; Verschueren, Karine; van Schooten, Erik; Jak, Suzanne; Pianta, Robert C</p> <p>2012-04-01</p> <p>The Student-Teacher Relationship Scale (STRS) is widely used to examine teachers' relationships with young students in terms of closeness, conflict, and dependency. This study aimed to verify the dimensional structure of the STRS with confirmatory factor analysis, test its measurement invariance across child gender and age, improve its measurement of the dependency construct, and extend its age range. Teachers completed a slightly adapted STRS for a Dutch sample of 2335 children aged 3 to 12. Overall, the 3-factor model showed an acceptable fit. Results indicated metric invariance across gender and age up to 8years. Scalar invariance generally did not hold. Lack of metric invariance at ages 8 to 12 primarily involved Conflict items, whereas scale differences across gender and age primarily involved Closeness items. The adapted Dependency scale showed strong invariance and higher internal consistencies than the original scale for this Dutch sample. Importantly, the revealed non-invariance for gender and age did not influence mean group comparisons. Copyright © 2011 Society for the Study of School Psychology. Published by Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29531514','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29531514"><span>Assessing age stereotypes in the German population in 1996 and 2011: socio-demographic correlates and shift over time.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Spangenberg, Lena; Zenger, Markus; Glaesmer, Heide; Brähler, Elmar; Strauss, Bernhard</p> <p>2018-03-01</p> <p>The present study aimed to extend the knowledge regarding dimensionality, socio-demographic correlates and shifts in age stereotypes over the past 15 years using a time-sequential design. In 1996 and 2011, we assessed age stereotypes in two independent samples of the German population aged ≥ 45 years ( N = 970 in sample 1, N = 1545 in sample 2). Three scales with six items each were assessed. Two scales cover negative (i.e., rigidity/isolation, burden), and one scale covers positive age stereotypes (wisdom/experience). Dimensionality of the scale, associations with socio-demographic variables and whether the stereotypes have shifted were tested using confirmatory factor analyses, structural equation modeling and analyses of variances. Three dimensions were identified and replicated following an exploratory as well as a confirmatory approach. Age stereotypes did shift between 1996 and 2011 in the dimension burden (i.e., becoming more negative). Our results further underpin the finding that age stereotypes are multifaceted and suggest that dimensions do not change over time. Additionally, our data provide some evidence that societal age stereotypes partly change over time.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=Women+AND+men+AND+employment&pg=5&id=EJ903266','ERIC'); return false;" href="https://eric.ed.gov/?q=Women+AND+men+AND+employment&pg=5&id=EJ903266"><span>Paths to Success in Young Adulthood from Mental Health and Life Transitions in Emerging Adulthood</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Howard, Andrea L.; Galambos, Nancy L.; Krahn, Harvey J.</p> <p>2010-01-01</p> <p>This study followed a school-based sample (N = 920) to explore how trajectories of depressive symptoms and expressed anger from age 18 to 25, along with important life transitions, predicted life and career satisfaction at age 32. A two-group (women and men) bivariate growth model revealed that higher depressive symptoms at age 18 predicted lower…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2001E%26PSL.184..489H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2001E%26PSL.184..489H"><span>Pb isotope compositions of modern deep sea turbidites</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Hemming, S. R.; McLennan, S. M.</p> <p>2001-01-01</p> <p>Modern deep sea turbidite muds and sands collected from Lamont piston cores represent a large range in age of detrital sources as well as a spectrum of tectonic settings. Pb isotope compositions of all but three of the 66 samples lie to the right of the 4.56 Ga Geochron, and most also lie along a slope consistent with a time-integrated κ ( 232Th/ 238U) between 3.8 and 4.2. Modern deep sea turbidites show a predictable negative correlation between both Pb and Sr isotope ratios and ɛNd and ɛHf, clearly related to the age of continental sources. However, the consistency between Pb and Nd isotopes breaks down for samples with very old provenance ( ɛNd<-20) that are far less radiogenic than predicted by the negative correlation. The correlations among Sr, Nd and Hf isotopes also become more scattered in samples with very old provenance. The unradiogenic Pb isotopic character of modern sediments with Archean Nd model ages is consistent with a model where Th and U abundances of the Archean upper crust are significantly lower than the post-Archean upper crust.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28636746','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28636746"><span>Evaluation of the Parent-Report Inventory of Callous-Unemotional Traits in a Sample of Children Recruited from Intimate Partner Violence Services: A Multidimensional Rasch Analysis.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>McDonald, Shelby Elaine; Ma, Lin; Green, Kathy E; Hitti, Stephanie A; Cody, Anna M; Donovan, Courtney; Williams, James Herbert; Ascione, Frank R</p> <p>2018-03-01</p> <p>Our study applied multidimensional item response theory (MIRT) to compare structural models of the parent-report version of the Inventory of Callous and Unemotional Traits (ICU; English and North American Spanish translations). A total of 291 maternal caregivers were recruited from community-based domestic violence services and reported on their children (77.9% ethnic minority; 47% female), who ranged in age from 7 to 12 years (mean = 9.07, standard deviation = 1.64). We compared 9 models that were based on prior psychometric evaluations of the ICU. MIRT analyses indicated that a revised 18-item version comprising 2 factors (callous-unemotional and empathic-prosocial) was more suitable for our sample. Differential item functioning was found for several items across ethnic and language groups, but not for child gender or age. Evidence of construct validity was found. We recommend continued research and revisions to the ICU to better assess the presence of callous-unemotional traits in community samples of school-age children. © 2017 Wiley Periodicals, Inc.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018MNRAS.477..578C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018MNRAS.477..578C"><span>High-resolution observations of low-luminosity gigahertz-peaked spectrum and compact steep-spectrum sources</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Collier, J. D.; Tingay, S. J.; Callingham, J. R.; Norris, R. P.; Filipović, M. D.; Galvin, T. J.; Huynh, M. T.; Intema, H. T.; Marvil, J.; O'Brien, A. N.; Roper, Q.; Sirothia, S.; Tothill, N. F. H.; Bell, M. E.; For, B.-Q.; Gaensler, B. M.; Hancock, P. J.; Hindson, L.; Hurley-Walker, N.; Johnston-Hollitt, M.; Kapińska, A. D.; Lenc, E.; Morgan, J.; Procopio, P.; Staveley-Smith, L.; Wayth, R. B.; Wu, C.; Zheng, Q.; Heywood, I.; Popping, A.</p> <p>2018-06-01</p> <p>We present very long baseline interferometry observations of a faint and low-luminosity (L1.4 GHz < 1027 W Hz-1) gigahertz-peaked spectrum (GPS) and compact steep-spectrum (CSS) sample. We select eight sources from deep radio observations that have radio spectra characteristic of a GPS or CSS source and an angular size of θ ≲ 2 arcsec, and detect six of them with the Australian Long Baseline Array. We determine their linear sizes, and model their radio spectra using synchrotron self-absorption (SSA) and free-free absorption (FFA) models. We derive statistical model ages, based on a fitted scaling relation, and spectral ages, based on the radio spectrum, which are generally consistent with the hypothesis that GPS and CSS sources are young and evolving. We resolve the morphology of one CSS source with a radio luminosity of 10^{25} W Hz^{-1}, and find what appear to be two hotspots spanning 1.7 kpc. We find that our sources follow the turnover-linear size relation, and that both homogeneous SSA and an inhomogeneous FFA model can account for the spectra with observable turnovers. All but one of the FFA models do not require a spectral break to account for the radio spectrum, while all but one of the alternative SSA and power-law models do require a spectral break to account for the radio spectrum. We conclude that our low-luminosity sample is similar to brighter samples in terms of their spectral shape, turnover frequencies, linear sizes, and ages, but cannot test for a difference in morphology.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/10777972','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/10777972"><span>Age at first intercourse in an Australian national sample of technical college students.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Grunseit, A C; Richters, J</p> <p>2000-02-01</p> <p>This study aims to broaden the current body of knowledge regarding the sexual behaviour of young Australians by examining the age and correlates of age of first intercourse in a national sample of Technical and Further Education apprentices. In 1995, students at randomly selected technical colleges in Australia were surveyed on HIV-related issues. Questionnaires were administered to a stratified cluster sample of automotive, hairdressing and commercial cookery apprentices. Respondents were asked the age at which they first had heterosexual vaginal or anal intercourse. Of 4,055 respondents aged 15-24 years, 3,848 answered the question; 3,195 (83%) had had intercourse. Males and females did not differ significantly. Median age at first intercourse was 16 (range 12-23). In multivariate analysis, older age at first intercourse was associated with: greater age at interview; higher school education; church attendance; and State of residence. The model, however, accounted for only 14% of the variance in age at first intercourse. In this sample, those apprentices who completed secondary school became sexually active later on average than those who left before the end of Year 10. For sex education to occur before sexual initiation, it needs to be offered in primary schools and the first year of high school (aged 11-13 years). Further, as technical college students are likely to initiate sex earlier than their age mates still at school, colleges may be in a position to take responsibility for the continuing sexual education of this group, especially for those students entering college at 15 or 16 years of age.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015EGUGA..17..567N','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015EGUGA..17..567N"><span>Thermal history and evolution of the Rio de Janeiro - Barbacena section of the southeastern Brazilian continental margin</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Neri Gezatt, Julia; Stephenson, Randell; Macdonald, David</p> <p>2015-04-01</p> <p>The transect between the Brazilian cities of Rio de Janeiro and Barbacena (22°54'S, 43°12'W and 21°13'S, 43°46'W, respectively) runs through a segment of a complex range of N-NE/S-SW trending basement units of the Ribeira Belt and southern Sao Francisco Craton, intensely reworked during the Brasiliano-Pan-African orogenic cycle. The ortho- and paragneisses in the area have metamorphic ages between 650 and 540 Ma and are intruded by pre-, syn- and post-tectonic granitic bodies. The transect, perpendicular to the strike direction of the continental margin, crosses the Serra do Mar escarpment, where the sample density is higher in order to better constrain occasional significant age changes. For logistical reasons, the 40 samples collected were processed in two separate batches for apatite fission track (AFT) analysis. The first batch comprised 19 samples, from which 15 produced fission track ages. Analyses were carried out at University College London (UCL), following standard procedures. Preliminary results for the study show AFT ages between 85.9±6.3 and 54.1±4.2 Ma, generally with younger ages close to the coast and progressively older ages towards the continental interior. The highest area sampled, around the city of Teresopolis, ranges from 740 to 1216 m above sea level and shows ages between 85.9±6.3 and 71.3±5.3 Ma. There is no evident lithological or structural distribution control. Medium track length values range from 12.57 to 13.89 µm and distributions are unimodal. Thermal history modelling was done using software QTQt. Individual sample model cooling curves can be divided into two groups: a dominant one, showing a single, slower cooling trend, and a second one with a rapid initial cooling curve, which becomes less steep around 65 Ma. In both groups the maximum paleotemperatures are around 110 Ma. The thermal history model for the first batch of samples is compatible with a single cooling event for the area following continental rifting and formation of the Atlantic Ocean. The preliminary results add to the growing thermochronological data base for the southeastern Brazilian continental margin and to deciphering the complex evolution of the region, as well as to the knowledge about the development and evolution of divergent continental margins in general. In a regional setting, AFT ages from this study, though not broadly variant locally, are distinct from basement rock AFT ages for adjacent areas produced by other authors along the southeastern continental margin. Similar ages are found at the southern Bocaina Plateau, for example, where structural control of age distribution is evident. Such regional thermal age difference has been previously attributed to continental scale structural compartmentalization throughout the continental passive margin, related to Late Cretaceous and Cenozoic reactivation of the E-W fracture zones linked to rifting of the South Atlantic. The present AFT results are compatible with Late Cretaceous reactivation but show no relation with younger events.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20079555','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20079555"><span>Some guidelines for structural equation modelling in cognitive neuroscience: the case of Charlton et al.'s study on white matter integrity and cognitive ageing.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Penke, Lars; Deary, Ian J</p> <p>2010-09-01</p> <p>Charlton et al. (2008) (Charlton, R.A., Landua, S., Schiavone, F., Barrick, T.R., Clark, C.A., Markus, H.S., Morris, R.G.A., 2008. Structural equation modelling investigation of age-related variance in executive function and DTI-measured white matter change. Neurobiol. Aging 29, 1547-1555) presented a model that suggests a specific age-related effect of white matter integrity on working memory. We illustrate potential pitfalls of structural equation modelling by criticizing their model for (a) its neglect of latent variables, (b) its complexity, (c) its questionable causal assumptions, (d) the use of empirical model reduction, (e) the mix-up of theoretical perspectives, and (f) the failure to compare alternative models. We show that a more parsimonious model, based solely on the well-established general factor of cognitive ability, fits their data at least as well. Importantly, when modelled this way there is no support for a role of white matter integrity in cognitive aging in this sample, indicating that their conclusion is strongly dependent on how the data are analysed. We suggest that evidence from more conclusive study designs is needed. Copyright 2009 Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29701751','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29701751"><span>Lifespan Trajectories of White Matter Changes in Rhesus Monkeys.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kubicki, M; Baxi, M; Pasternak, O; Tang, Y; Karmacharya, S; Chunga, N; Lyall, A E; Rathi, Y; Eckbo, R; Bouix, S; Mortazavi, F; Papadimitriou, G; Shenton, M E; Westin, C F; Killiany, R; Makris, N; Rosene, D L</p> <p>2018-04-26</p> <p>Progress in neurodevelopmental brain research has been achieved through the use of animal models. Such models not only help understanding biological changes that govern brain development, maturation and aging, but are also essential for identifying possible mechanisms of neurodevelopmental and age-related chronic disorders, and to evaluate possible interventions with potential relevance to human disease. Genetic relationship of rhesus monkeys to humans makes those animals a great candidate for such models. With the typical lifespan of 25 years, they undergo cognitive maturation and aging that is similar to this observed in humans. Quantitative structural neuroimaging has been proposed as one of the candidate in vivo biomarkers for tracking white matter brain maturation and aging. While lifespan trajectories of white matter changes have been mapped in humans, such knowledge is not available for nonhuman primates. Here, we analyze and model lifespan trajectories of white matter microstructure using in vivo diffusion imaging in a sample of 44 rhesus monkeys. We report quantitative parameters (including slopes and peaks) of lifespan trajectories for 8 individual white matter tracts. We show different trajectories for cellular and extracellular microstructural imaging components that are associated with white matter maturation and aging, and discuss similarities and differences between those in humans and rhesus monkeys, the importance of our findings, and future directions for the field.Significance Statement: Quantitative structural neuroimaging has been proposed as one of the candidate in vivo biomarkers for tracking brain maturation and aging. While lifespan trajectories of structural white matter changes have been mapped in humans, such knowledge is not available for rhesus monkeys. We present here results of the analysis and modeling of the lifespan trajectories of white matter microstructure using in vivo diffusion imaging in a sample of 44 rhesus monkeys (age 4-27). We report and anatomically map lifespan changes related to cellular and extracellular microstructural components that are associated with white matter maturation and aging.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22340327-age-determination-old-intermediate-age-small-magellanic-cloud-star-clusters','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22340327-age-determination-old-intermediate-age-small-magellanic-cloud-star-clusters"><span>Age determination of 15 old to intermediate-age small Magellanic cloud star clusters</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Parisi, M. C.; Clariá, J. J.; Piatti, A. E.</p> <p>2014-04-01</p> <p>We present color-magnitude diagrams in the V and I bands for 15 star clusters in the Small Magellanic Cloud (SMC) based on data taken with the Very Large Telescope (VLT, Chile). We selected these clusters from our previous work, wherein we derived cluster radial velocities and metallicities from calcium II infrared triplet (CaT) spectra also taken with the VLT. We discovered that the ages of six of our clusters have been appreciably underestimated by previous studies, which used comparatively small telescopes, graphically illustrating the need for large apertures to obtain reliable ages of old and intermediate-age SMC star clusters. Inmore » particular, three of these clusters, L4, L6, and L110, turn out to be among the oldest SMC clusters known, with ages of 7.9 ± 1.1, 8.7 ± 1.2, and 7.6 ± 1.0 Gyr, respectively, helping to fill a possible 'SMC cluster age gap'. Using the current ages and metallicities from Parisi et al., we analyze the age distribution, age gradient, and age-metallicity relation (AMR) of a sample of SMC clusters measured homogeneously. There is a suggestion of bimodality in the age distribution but it does not show a constant slope for the first 4 Gyr, and we find no evidence for an age gradient. Due to the improved ages of our cluster sample, we find that our AMR is now better represented in the intermediate/old period than we had derived in Parisi et al., where we simply took ages available in the literature. Additionally, clusters younger than ∼4 Gyr now show better agreement with the bursting model of Pagel and Tautvaišienė, but we confirm that this model is not a good representation of the AMR during the intermediate/old period. A more complicated model is needed to explain the SMC chemical evolution in that period.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5479740','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5479740"><span>From alcohol initiation to tolerance to problems: Discordant twin modeling of a developmental process</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Deutsch, Arielle R.; Slutske, Wendy S.; Lynskey, Michael T.; Bucholz, Kathleen K.; Madden, Pamela A. F.; Heath, Andrew C.; Martin, Nicholas G.</p> <p>2017-01-01</p> <p>The current study examined a stage-based alcohol use trajectory model to test for potential causal effects of earlier drinking milestones on later drinking milestones in a combined sample of two cohorts of Australian monozygotic and same-sex dizygotic twins (N = 7,398, age M = 30.46, SD = 2.61, 61% mal 56% monozygotic twins). Ages of drinking, drunkenness, regular drinking, tolerance, first nontolerance alcohol use disorder symptom, and alcohol use disorder symptom onsets were assessed retrospectively. Ages of milestone attainment (i.e., age-of-onset) and time between milestones (i.e., time-to-even were examined via frailty models within a multilevel discordant twin design. For age-of-onset models, earlier ages of onset of antecedent drinking milestones increased hazards for earlier ages of onset for more proximal subsequent drinking milestones. For the time-to-event models, however, earlier ag of onset for the “starting” milestone decreased risk for a shorter time period between the starting and the “ending” milestone. Earlier age of onset of intermediate milestones between starting and ending drinking milestones had the opposite effect, increasing risk for a shorter time period between the starti and ending milestones. These results are consistent with a causal effect of an earlier age of drinking milestone onset on temporally proximal subsequent drinking milestones. PMID:27417028</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29058212','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29058212"><span>NAPR: a Cloud-Based Framework for Neuroanatomical Age Prediction.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Pardoe, Heath R; Kuzniecky, Ruben</p> <p>2018-01-01</p> <p>The availability of cloud computing services has enabled the widespread adoption of the "software as a service" (SaaS) approach for software distribution, which utilizes network-based access to applications running on centralized servers. In this paper we apply the SaaS approach to neuroimaging-based age prediction. Our system, named "NAPR" (Neuroanatomical Age Prediction using R), provides access to predictive modeling software running on a persistent cloud-based Amazon Web Services (AWS) compute instance. The NAPR framework allows external users to estimate the age of individual subjects using cortical thickness maps derived from their own locally processed T1-weighted whole brain MRI scans. As a demonstration of the NAPR approach, we have developed two age prediction models that were trained using healthy control data from the ABIDE, CoRR, DLBS and NKI Rockland neuroimaging datasets (total N = 2367, age range 6-89 years). The provided age prediction models were trained using (i) relevance vector machines and (ii) Gaussian processes machine learning methods applied to cortical thickness surfaces obtained using Freesurfer v5.3. We believe that this transparent approach to out-of-sample evaluation and comparison of neuroimaging age prediction models will facilitate the development of improved age prediction models and allow for robust evaluation of the clinical utility of these methods.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28707524','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28707524"><span>Applicability of Cameriere's and Drusini's age estimation methods to a sample of Turkish adults.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hatice, Boyacioglu Dogru; Nihal, Avcu; Nursel, Akkaya; Humeyra Ozge, Yilanci; Goksuluk, Dincer</p> <p>2017-10-01</p> <p>The aim of this study was to investigate the applicability of Drusini's and Cameriere's methods to a sample of Turkish people. Panoramic images of 200 individuals were allocated into two groups as study and test groups and examined by two observers. Tooth coronal indexes (TCI), which is the ratio between coronal pulp cavity height and crown height, were calculated in the mandibular first and second premolars and molars. Pulp/tooth area ratios (ARs) were calculated in the maxillary and mandibular canine teeth. Study group measurements were used to derive a regression model. Test group measurements were used to evaluate the accuracy of the regression model. Pearson's correlation coefficients and regression analysis were used. The correlations between TCIs and age were -0.230, -0.301, -0.344 and -0.257 for mandibular first premolar, second premolar, first molar and second molar, respectively. Those for the maxillary canine (MX) and mandibular canine (MN) ARs were -0.716 and -0.514, respectively. The MX ARs were used to build the linear regression model that explained 51.2% of the total variation, with a standard error of 9.23 years. The mean error of the estimates in test group was 8 years and age of 64% of the individuals were estimated with an error of <±10 years which is acceptable in forensic age prediction. The low correlation coefficients between age and TCI indicate that Drusini's method was not applicable to the estimation of age in a Turkish population. Using Cameriere's method, we derived a regression model.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27165965','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27165965"><span>Resilience, age, and perceived symptoms in persons with long-term physical disabilities.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Terrill, Alexandra L; Molton, Ivan R; Ehde, Dawn M; Amtmann, Dagmar; Bombardier, Charles H; Smith, Amanda E; Jensen, Mark P</p> <p>2016-05-01</p> <p>Resilience may mitigate impact of secondary symptoms such as pain and fatigue on quality of life in persons aging with disability. This study examined resilience in a large sample of individuals with disabling medical conditions by validating the Connor-Davidson Resilience Scale, obtaining descriptive information about resilience and evaluating resilience as a mediator among key secondary symptoms and quality of life using structural equation modeling. Results indicated that the measure's psychometric properties were adequate in this sample. Resilience was lowest among participants who were middle-aged or younger, and participants with depression. Resilience mediated associations between secondary symptoms and quality of life. © The Author(s) 2014.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li class="active"><span>9</span></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_9 --> <div id="page_10" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li class="active"><span>10</span></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="181"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25411124','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25411124"><span>Dispositional and Environmental Predictors of the Development of Internalizing Problems in Childhood: Testing a Multilevel Model.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hastings, Paul D; Helm, Jonathan; Mills, Rosemary S L; Serbin, Lisa A; Stack, Dale M; Schwartzman, Alex E</p> <p>2015-07-01</p> <p>This investigation evaluated a multilevel model of dispositional and environmental factors contributing to the development of internalizing problems from preschool-age to school-age. In a sample of 375 families (185 daughters, 190 sons) drawn from three independent samples, preschoolers' behavioral inhibition, cortisol and gender were examined as moderators of the links between mothers' negative parenting behavior, negative emotional characteristics, and socioeconomic status when children were 3.95 years, and their internalizing problems when they were 8.34 years. Children's dispositional characteristics moderated all associations between these environmental factors and mother-reported internalizing problems in patterns that were consistent with either diathesis-stress or differential-susceptibility models of individual-environment interaction, and with gender models of developmental psychopathology. Greater inhibition and lower socioeconomic status were directly predictive of more teacher reported internalizing problems. These findings highlight the importance of using multilevel models within a bioecological framework to understand the complex pathways through which internalizing difficulties develop.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19737499','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19737499"><span>A conceptual model predicting internalizing problems in middle childhood among children of alcoholic and nonalcoholic fathers: the role of marital aggression.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Eiden, Rina D; Molnar, Danielle S; Colder, Craig; Edwards, Ellen P; Leonard, Kenneth E</p> <p>2009-09-01</p> <p>The purpose of this study was to test a conceptual model predicting children's anxiety/depression in middle childhood in a community sample of children with parents who had alcohol problems (n = 112) and those without alcohol problems (n = 101). The conceptual model examined the role of parents' alcohol diagnoses, depression, and antisocial behavior among parents of children ages 12 months to kindergarten age in predicting marital aggression and parental aggravation. Higher levels of marital aggression and parental aggravation were hypothesized to predict children's depression/anxiety within time (18 months to kindergarten age and, prospectively, to age during fourth grade). The sample was recruited from New York State birth records when the children were 12 months old. Assessments were conducted at 12, 18, 24, and 36 months; at kindergarten age; and during fourth grade. Children with alcoholic fathers had higher depression/anxiety scores according to parental reports but not self-reports. Structural equations modeling was largely supportive of the conceptual model. Fathers' alcoholism was associated with higher child anxiety via greater levels of marital aggression among families with alcohol problems. Results also indicated that there was a significant indirect association between parents' depression symptoms and child anxiety via marital aggression. The results highlight the nested nature of risk characteristics in alcoholic families and the important role of marital aggression in predicting children's anxiety/depression. Interventions targeting both parents' alcohol problems and associated marital aggression are likely to provide the dual benefits of improving family interactions and lowering risk of children's internalizing behavior problems.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28807195','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28807195"><span>Characterizing the relationship between age and venous thromboembolism in adult trauma patients: findings from the National Trauma Data Bank and the National Inpatient Sample.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Nastasi, Anthony J; Canner, Joseph K; Lau, Brandyn D; Streiff, Michael B; Aboagye, Jonathan K; Kraus, Peggy S; Hobson, Deborah B; Van Arendonk, Kyle J; Haut, Elliott R</p> <p>2017-08-01</p> <p>Venous thromboembolism (VTE) is a tremendous burden in health care. However, current guidelines lack recommendations regarding the prevention of VTE in older adult trauma patients. Furthermore, the appropriate method of modeling of age in VTE models is currently unclear. Patients included in the National Trauma Data Bank (NTDB) between the years 2008 and 2014 and patients included in the National Inpatient Sample (NIS) between 2009 and 2013 were analyzed. Multiple logistic regression of VTE on age was performed. Of 3,598,881 patients in the NTDB, 34,202 (1.0%) were diagnosed with VTE compared to 5405 (1.1%) of the 505,231 patients in NIS. In both the fully adjusted NTDB and NIS model, age was positively associated with odds of VTE diagnosis under 65 years (NTDB, adjusted odds ratio [aOR]: 1.018, 95% confidence interval [CI]: 1.017-1.019, P < 0.001; NIS, aOR: 1.025, 95% CI 1.022-1.027, P < 0.001). In patients aged ≥65 years, age was negatively associated with odds of VTE diagnosis in the NTDB (aOR: 0.995, 95% CI: 0.992-0.999, P = 0.006) but not in the NIS (aOR: 0.998, 95% CI 0.994-1.002, P = 0.26). Incidence of VTE among adult trauma patients steadily increases with age until 65 years, after which the odds of VTE appear to level off or even slightly decrease. These findings should be applied for improved modeling of VTE in trauma patients. The mechanism behind these findings should be explored before using them to update guidelines for standardized VTE prevention in older adults. Copyright © 2017 Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26751689','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26751689"><span>First Direct Evidence for Natal Wintering Ground Fidelity and Estimate of Juvenile Survival in the New Zealand Southern Right Whale Eubalaena australis.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Carroll, E L; Fewster, R M; Childerhouse, S J; Patenaude, N J; Boren, L; Baker, C S</p> <p>2016-01-01</p> <p>Juvenile survival and recruitment can be more sensitive to environmental, ecological and anthropogenic factors than adult survival, influencing population-level processes like recruitment and growth rate in long-lived, iteroparous species such as southern right whales. Conventionally, Southern right whales are individually identified using callosity patterns, which do not stabilise until 6-12 months, by which time the whale has left its natal wintering grounds. Here we use DNA profiling of skin biopsy samples to identify individual Southern right whales from year of birth and document their return to the species' primary wintering ground in New Zealand waters, the Subantarctic Auckland Islands. We find evidence of natal fidelity to the New Zealand wintering ground by the recapture of 15 of 57 whales, first sampled in year of birth and available for subsequent recapture, during winter surveys to the Auckland Islands in 1995-1998 and 2006-2009. Four individuals were recaptured at the ages of 9 to 11, including two females first sampled as calves in 1998 and subsequently resampled as cows with calves in 2007. Using these capture-recapture records of known-age individuals, we estimate changes in survival with age using Cormack-Jolly-Seber models. Survival is modelled using discrete age classes and as a continuous function of age. Using a bootstrap method to account for uncertainty in model selection and fitting, we provide the first direct estimate of juvenile survival for this population. Our analyses indicate a high annual apparent survival for juveniles at between 0.87 (standard error (SE) 0.17, to age 1) and 0.95 (SE 0.05: ages 2-8). Individual identification by DNA profiling is an effective method for long-term demographic and genetic monitoring, particularly in animals that change identifiable features as they develop or experience tag loss over time.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4709107','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4709107"><span>First Direct Evidence for Natal Wintering Ground Fidelity and Estimate of Juvenile Survival in the New Zealand Southern Right Whale Eubalaena australis</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Carroll, E. L.; Fewster, R. M.; Childerhouse, S. J.; Patenaude, N. J.; Boren, L.; Baker, C. S.</p> <p>2016-01-01</p> <p>Juvenile survival and recruitment can be more sensitive to environmental, ecological and anthropogenic factors than adult survival, influencing population-level processes like recruitment and growth rate in long-lived, iteroparous species such as southern right whales. Conventionally, Southern right whales are individually identified using callosity patterns, which do not stabilise until 6–12 months, by which time the whale has left its natal wintering grounds. Here we use DNA profiling of skin biopsy samples to identify individual Southern right whales from year of birth and document their return to the species’ primary wintering ground in New Zealand waters, the Subantarctic Auckland Islands. We find evidence of natal fidelity to the New Zealand wintering ground by the recapture of 15 of 57 whales, first sampled in year of birth and available for subsequent recapture, during winter surveys to the Auckland Islands in 1995–1998 and 2006–2009. Four individuals were recaptured at the ages of 9 to 11, including two females first sampled as calves in 1998 and subsequently resampled as cows with calves in 2007. Using these capture-recapture records of known-age individuals, we estimate changes in survival with age using Cormack-Jolly-Seber models. Survival is modelled using discrete age classes and as a continuous function of age. Using a bootstrap method to account for uncertainty in model selection and fitting, we provide the first direct estimate of juvenile survival for this population. Our analyses indicate a high annual apparent survival for juveniles at between 0.87 (standard error (SE) 0.17, to age 1) and 0.95 (SE 0.05: ages 2–8). Individual identification by DNA profiling is an effective method for long-term demographic and genetic monitoring, particularly in animals that change identifiable features as they develop or experience tag loss over time. PMID:26751689</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29512412','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29512412"><span>Optical Characterization of Paper Aging Based on Laser-Induced Fluorescence (LIF) Spectroscopy.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Zhang, Hao; Wang, Shun; Chang, Keke; Sun, Haifeng; Guo, Qingqian; Ma, Liuzheng; Yang, Yatao; Zou, Caihong; Wang, Ling; Hu, Jiandong</p> <p>2018-06-01</p> <p>Paper aging and degradation are growing concerns for those who are responsible for the conservation of documents, archives, and libraries. In this study, the paper aging was investigated using laser-induced fluorescence spectroscopy (LIFS), where the fluorescence properties of 47 paper samples with different ages were explored. The paper exhibits fluorescence in the blue-green spectral region with two peaks at about 448 nm and 480 nm under the excitation of 405 nm laser. Both fluorescence peaks changed in absolute intensities and thus the ratio of peak intensities was also influenced with the increasing ages. By applying principal component analysis (PCA) and k-means clustering algorithm, all 47 paper samples were classified into nine groups based on the differences in paper age. Then the first-derivative fluorescence spectral curves were proposed to figure out the relationship between the spectral characteristic and the paper age, and two quantitative models were established based on the changes of first-derivative spectral peak at 443 nm, where one is an exponential fitting curve with an R-squared value of 0.99 and another is a linear fitting curve with an R-squared value of 0.88. The results demonstrated that the combination of fluorescence spectroscopy and PCA can be used for the classification of paper samples with different ages. Moreover, the first-derivative fluorescence spectral curves can be used to quantitatively evaluate the age-related changes of paper samples.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28177542','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28177542"><span>Reduced prevalence and severity of wounds following implementation of the Champions for Skin Integrity model to facilitate uptake of evidence-based practice in aged care.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Edwards, Helen E; Chang, Anne M; Gibb, Michelle; Finlayson, Kathleen J; Parker, Christina; O'Reilly, Maria; McDowell, Jan; Shuter, Patricia</p> <p>2017-12-01</p> <p>To evaluate the implementation of the Champions for Skin Integrity model on facilitating uptake of evidence-based wound management and improving skin integrity in residents of aged care facilities. The incidence of skin tears, pressure injuries and leg ulcers increases with age, and such wounds can be a serious issue in aged care facilities. Older adults are not only at higher risk for wounds related to chronic disease but also injuries related to falls and manual handling requirements. A longitudinal, pre-post design. The Champions for Skin Integrity model was developed using evidence-based strategies for transfer of evidence into practice. Data were collected before and six months after implementation of the model. Data on wound management and skin integrity were obtained from two random samples of residents (n = 200 pre; n = 201 post) from seven aged care facilities. A staff survey was also undertaken (n = 126 pre; n = 143 post) of experience, knowledge and evidence-based wound management. Descriptive statistics were calculated for all variables. Where relevant, chi-square for independence or t-tests were used to identify differences between the pre-/postdata. There was a significant decrease in the number of residents with a wound of any type (54% pre vs 43% post, χ 2 4·2, p = 0·041), as well as a significant reduction in specific wound types, for example pressure injuries (24% pre vs 10% post, χ 2 14·1, p < 0·001), following implementation of the model. An increase in implementation of evidence-based wound management and prevention strategies was observed in the postimplementation sample in comparison with the preimplementation sample. This included use of limb protectors and/or protective clothing 6% pre vs 20% post (χ 2 17·0, p < 0·001) and use of an emollient or soap alternative for bathing residents (50% pre vs 74% post, χ 2 13·9, p = 0·001). Implementation of the model in this sample fostered an increase in implementation of evidence-based wound management and prevention strategies, which was associated with a decrease in the prevalence and severity of wounds. This study suggests the Champions for Skin Integrity model has the potential to improve uptake of evidence-based wound management and improve skin integrity for older adults. © 2017 John Wiley & Sons Ltd.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70035303','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70035303"><span>Protracted construction of gabbroic crust at a slow spreading ridge: Constraints from 206Pb/238U zircon ages from Atlantis Massif and IODP Hole U1309D (30°N, MAR)</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Grimes, Craig B.; John, Barbara E.; Cheadle, Michael J.; Wooden, Joseph L.</p> <p>2008-01-01</p> <p>Sensitive high-resolution ion microprobe (SHRIMP) U-Pb zircon ages of 24 samples from oceanic crust recovered in Integrated Ocean Drilling Program (IODP) Hole U1309D and from the surface of Atlantis Massif, Mid-Atlantic Ridge (MAR) (30°N) document a protracted history of accretion in the footwall to an oceanic detachment fault. Ages for 18 samples of evolved Fe-Ti oxide gabbro and felsic dikes collected 40–1415 m below seafloor in U1309D yield a weighted mean of 1.20 ± 0.03 Ma (mean square of weighted deviates = 7.1). However, the ages range from 1.08 ± 0.07 Ma and 1.28 ± 0.05 Ma indicating crustal construction occurred over a minimum of 100–200 ka. The zircon ages, along with petrologic observations, indicate at least 2 major periods of intrusive activity with age peaks separated by 70 ka. The oldest ages are observed below 600 mbsf, an observation inconsistent with models requiring constant depth melt intrusion beneath a detachment fault. The data are most consistent with a “multiple sill” model whereby sills intrude at random depths below the ridge axis over a length scale greater than 1.4 km. Zircon ages from broadly spaced samples collected along the southern ridge of Atlantis Massif yield a detachment fault slip rate of 28.7 ± 6.7 mm/a and imply significant asymmetric plate spreading (up to 100% on the North American plate) for at least 200 ka during core complex formation.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28364476','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28364476"><span>Sleep and Cognitive Performance From Teens To Old Age: More Is Not Better.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Richards, Anne; Inslicht, Sabra S; Metzler, Thomas J; Mohlenhoff, Brian S; Rao, Madhu N; O'Donovan, Aoife; Neylan, Thomas C</p> <p>2017-01-01</p> <p>To determine the interaction of age and habitual sleep duration in predicting cognitive performance in a large sample of participants aged 15 to 89 years. This study is a cross-sectional analysis of performance data gathered between January 2012 and September 2013. First-time players (N = 512823) of three internet cognitive training games measuring processing speed, working memory, visuospatial memory, and arithmetic participated in the study. Performance was based on a measure of speed and accuracy for each game. The relationship between performance and self-reported habitual sleep duration was examined in the sample as a whole and across 10-year age groups starting at age 15 and ending at 75 and older. Performance peaked at 7 h of sleep duration for all three games in the sample as a whole, and the decrements in performance for sleep durations greater than 7 h were either comparable or greater in the youngest as compared to the oldest age groups. These findings challenge the hypothesis that deteriorating cognitive performance with long sleep duration is driven by medical comorbidities associated with aging. Further, these data are consistent with an optimal dose model of sleep and suggest that the model for the homeostatic recovery of cognitive function as a function of sleep duration should incorporate a curvilinear decline with longer duration sleep, indicating that there may be a cost to increased sleep. Replication and further research is essential for clarifying the sleep duration-cognition relationship in youth and adults of all ages. © Sleep Research Society 2017. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ852392.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ852392.pdf"><span>Correlates of Lifetime Physical Activity in Young Women</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Wallace, Lorraine Silver</p> <p>2003-01-01</p> <p>This study retrospectively examined physical activity patterns across three specific age periods (childhood, teenage, and young adulthood) in a cross sectional sample of young Caucasian undergraduate women (N = 44). All women (mean age = 22.27 plus or minus 3.14 years) completed questionnaire packets assessing transtheoretical model of behavior…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23587979','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23587979"><span>Determining population and developmental pharmacokinetics of metronidazole using plasma and dried blood spot samples from premature infants.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Cohen-Wolkowiez, Michael; Sampson, Mario; Bloom, Barry T; Arrieta, Antonio; Wynn, James L; Martz, Karen; Harper, Barrie; Kearns, Gregory L; Capparelli, Edmund V; Siegel, David; Benjamin, Daniel K; Smith, P Brian</p> <p>2013-09-01</p> <p>Limited pharmacokinetic (PK) data of metronidazole in premature infants have led to various dosing recommendations. Surrogate efficacy targets for metronidazole are ill-defined and therefore aimed to exceed minimum inhibitory concentration of organisms responsible for intra-abdominal infections. We evaluated the PK of metronidazole using plasma and dried blood spot samples from infants ≤32 weeks gestational age in an open-label, PK, multicenter (N = 3) study using population PK modeling (NONMEM). Monte Carlo simulations (N = 1000 virtual subjects) were used to evaluate the surrogate efficacy target. Metabolic ratios of parent and metabolite were calculated. Twenty-four premature infants (111 plasma and 51 dried blood spot samples) were enrolled: median (range) gestational age at birth 25 (23-31) weeks, postnatal age 27 (1-82) days, postmenstrual age 31 (24-39) weeks and weight 740 (431-1466) g. Population clearance (L/h/kg) was 0.038 × (postmenstrual age/30) and volume of distribution (L/kg) of 0.93. PK parameter estimates and precision were similar between plasma and dried blood spot samples. Metabolic ratios correlated with clearance. Simulations suggested the majority of infants in the neonatal intensive care unit (>80%) would meet the surrogate efficacy target using postmenstrual age-based dosing.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/1351823','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/1351823"><span>Method, system, and computer-readable medium for determining performance characteristics of an object undergoing one or more arbitrary aging conditions</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Gering, Kevin L.</p> <p></p> <p>A method, system, and computer-readable medium are described for characterizing performance loss of an object undergoing an arbitrary aging condition. Baseline aging data may be collected from the object for at least one known baseline aging condition over time, determining baseline multiple sigmoid model parameters from the baseline data, and performance loss of the object may be determined over time through multiple sigmoid model parameters associated with the object undergoing the arbitrary aging condition using a differential deviation-from-baseline approach from the baseline multiple sigmoid model parameters. The system may include an object, monitoring hardware configured to sample performance characteristics ofmore » the object, and a processor coupled to the monitoring hardware. The processor is configured to determine performance loss for the arbitrary aging condition from a comparison of the performance characteristics of the object deviating from baseline performance characteristics associated with a baseline aging condition.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23376267','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23376267"><span>Hydrolysis of Baltic amber during thermal ageing--an infrared spectroscopic approach.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Pastorelli, Gianluca; Shashoua, Yvonne; Richter, Jane</p> <p>2013-04-01</p> <p>To enable conservation of amber in museums, understanding of chemical changes is crucial. While oxidation has been investigated particularly well for this natural polymer, further degradation phenomena in relation to humidity and pollutants are poorly studied or still unknown. Attenuated total reflectance-Fourier transform infrared spectroscopy was explored with regard to Baltic amber. A systematic spectroscopic survey of a wide range of thermally aged model amber samples, exposed to different microclimatic conditions, showed significant changes in their spectra. Samples aged in a humid and acidic environment or exposed to a humid and alkaline atmosphere generally exhibited a higher absorbance intensity of carbonyl groups at frequencies assigned to acids than unaged samples, samples aged in drier conditions and samples immersed in an alkaline solution. Baltic amber comprises succinate ester, which may be hydrolysed into communol and succinic acid. The survey thus provided evidence about the progress of hydrolytic reactions during degradation of Baltic amber. Infrared spectroscopy was shown to have significant potential for providing qualitative and quantitative chemical information on hydrolysis of amber, which will be of interest for the development of preventive conservation techniques for museum collections of amber objects. Copyright © 2013 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70036661','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70036661"><span>Modeled ground water age distributions</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Woolfenden, Linda R.; Ginn, Timothy R.</p> <p>2009-01-01</p> <p>The age of ground water in any given sample is a distributed quantity representing distributed provenance (in space and time) of the water. Conventional analysis of tracers such as unstable isotopes or anthropogenic chemical species gives discrete or binary measures of the presence of water of a given age. Modeled ground water age distributions provide a continuous measure of contributions from different recharge sources to aquifers. A numerical solution of the ground water age equation of Ginn (1999) was tested both on a hypothetical simplified one-dimensional flow system and under real world conditions. Results from these simulations yield the first continuous distributions of ground water age using this model. Complete age distributions as a function of one and two space dimensions were obtained from both numerical experiments. Simulations in the test problem produced mean ages that were consistent with the expected value at the end of the model domain for all dispersivity values tested, although the mean ages for the two highest dispersivity values deviated slightly from the expected value. Mean ages in the dispersionless case also were consistent with the expected mean ages throughout the physical model domain. Simulations under real world conditions for three dispersivity values resulted in decreasing mean age with increasing dispersivity. This likely is a consequence of an edge effect. However, simulations for all three dispersivity values tested were mass balanced and stable demonstrating that the solution of the ground water age equation can provide estimates of water mass density distributions over age under real world conditions.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://www.coopunits.org/Alabama/Research/Peer_Publications/2.7481231361E10/','USGSPUBS'); return false;" href="http://www.coopunits.org/Alabama/Research/Peer_Publications/2.7481231361E10/"><span>An evaluation of agreement between pectoral spines and otoliths for estimating ages of catfishes</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Olive, J.A.; Schramm, Harold; Gerard, Patrick D.; Irwin, E.</p> <p>2011-01-01</p> <p>Otoliths have been shown to provide more accurate ages than pectoral spine sections for several catfish populations; but sampling otoliths requires euthanizing the specimen, whereas spines can be sampled non-lethally. To evaluate whether, and under what conditions, spines provide the same or similar age estimates as otoliths, we examined data sets of individual fish aged from pectoral spines and otoliths for six blue catfish Ictalurus furcatus populations (n=420), 14 channel catfish Ictalurus punctatus populations (n=997), and 10 flathead catfish Pylodictus olivaris populations (n=947) from lotic and lentic waters throughout the central and eastern U.S. Logistic regression determined that agreement between ages estimated from otoliths and spines was consistently related to age, but inconsistently related to growth rate. When modeled at mean growth rate, we found at least 80% probability of no difference in spine- and otolith-assigned ages up to ages 4 and 5 for blue and channel catfish, respectively. For flathead catfish, an 80% probability of agreement between spine- and otolith-assigned ages did not occur at any age due to high incidence of differences in assigned ages even for age-1 fish. Logistic regression models predicted at least 80% probability that spine and otolith ages differed by ≤1 year up to ages 13, 16, and 9 for blue, channel, and flathead catfish, respectively. Age-bias assessment found mean spine-assigned age differed by less than 1 year from otolith-assigned age up to ages 19, 9, and 17 for blue catfish, channel catfish, and flathead catfish, respectively. These results can be used to help guide decisions about which structure is most appropriate for estimating catfish ages for particular populations and management objectives.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3117219','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3117219"><span>Age at menopause: imputing age at menopause for women with a hysterectomy with application to risk of postmenopausal breast cancer</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Rosner, Bernard; Colditz, Graham A.</p> <p>2011-01-01</p> <p>Purpose Age at menopause, a major marker in the reproductive life, may bias results for evaluation of breast cancer risk after menopause. Methods We follow 38,948 premenopausal women in 1980 and identify 2,586 who reported hysterectomy without bilateral oophorectomy, and 31,626 who reported natural menopause during 22 years of follow-up. We evaluate risk factors for natural menopause, impute age at natural menopause for women reporting hysterectomy without bilateral oophorectomy and estimate the hazard of reaching natural menopause in the next 2 years. We apply this imputed age at menopause to both increase sample size and to evaluate the relation between postmenopausal exposures and risk of breast cancer. Results Age, cigarette smoking, age at menarche, pregnancy history, body mass index, history of benign breast disease, and history of breast cancer were each significantly related to age at natural menopause; duration of oral contraceptive use and family history of breast cancer were not. The imputation increased sample size substantially and although some risk factors after menopause were weaker in the expanded model (height, and alcohol use), use of hormone therapy is less biased. Conclusions Imputing age at menopause increases sample size, broadens generalizability making it applicable to women with hysterectomy, and reduces bias. PMID:21441037</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AGUFM.T11C0473L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AGUFM.T11C0473L"><span>The significance of the Medicine Hat Block (southern Alberta, northern Montana) in the assembly of Laurentia: New interpretations from recent single grain zircon geochronological and geochemical data</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>LaDouceur, B. O.; Gifford, J.; Malone, S.; Davis, B.</p> <p>2017-12-01</p> <p>Keywords: Medicine Hat Block, Zircon, U/Pb ages, Hf isotopes, Laurentia The Medicine Hat Block (MHB) is one of the core cratonic elements that amalgamated in the Paleoproterozoic to form Laurentia. However, unlike many of the other cratons, the role of the MHB in the formation of Laurentia is poorly constrained. Virtually all of the MHB is concealed by Proterozoic and younger supracrustal sequences, limiting the data collected from this craton. The primary source of samples from the MHB comes from two sources: 1) xenoliths of variably metamorphoses gneisses, amphibolites, and meta-plutonic rocks collected from Eocene volcanic rock, and 2) similar lithologies recovered from boreholes that penetrate to the MHB basement. Multigrain zircon TIMS analyses yielded U/Pb ages ranging from 1.70 Ga to 3.26 Ga. Recent zircon single-grain LA-ICPMS U-Pb ages revealed a slightly older range of Archean ages, 2.63 Ga to 3.27 Ga, and two samples yielding Paleoproterozoic ages at 1.78 and 1.82 Ga. Whole-rock Sm/Nd data indicated that the samples formed from crustal sources, with model ages ranging between 1.80 Ga to 3.48 Ga. In-situ zircon Hf isotopic results revealed that Archean-aged zircon are generally suprachondritic, with eHf(t) values between 8.3 and -8.7. In contrast, the Paleoproterozoic grains yielded negative eHf(t) values ranging from -6.8 to -21.2, suggestive of a reworked Archean crustal component in their genesis. In particular, the Sweetgrass Hill xenolith suite is characterized solely by Paleoproterozoic ages, with evolved eHf(t) suggesting that any older U-Pb ages were reset by granulite facies metamorphism and zircon recrystallization. The combined U-Pb and Hf isotopic data from these samples helps illuminate the character of the MHB and its relationships to the Wyoming and Hearne cratons, as well as the Great Falls Tectonic Zone (GFTZ). The ages overlap between cratonic elements; however, the abundance of positive eHf(t) values of the 2.8 Ga ages suggests that the MHB is distinct from the Wyoming Craton, and that the GFTZ must indeed be a collisional zone as proposed by others. The Paleoproterozoic ages observed in the granulite xenolith samples supports this distinctness as well, and also supports proposed models of a Paleoproterozoic underplating event observed in other xenoliths and in seismic sections.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25588668','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25588668"><span>Osteometric sorting of skeletal elements from a sample of modern Colombians: a pilot study.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Rodríguez, Juan Manuel Guerrero; Hackman, Lucina; Martínez, Wendy; Medina, César Sanabria</p> <p>2016-03-01</p> <p>The Colombian armed conflict has been catalogued not only as the longest civil war in the western hemisphere, but also as having one of the highest indexes of missing persons. Among the several challenges faced by forensic practitioners in Colombia, the commingling of human remains has been recognised as one of the most difficult to approach. The method of osteometric sorting described by Byrd and Adams and Byrd (2008) has proven relevant as a powerful tool to aid in the reassociation process of skeletal structures. The aim of this research was to evaluate the three osteometric sorting models developed by Byrd (2008) (paired elements, articulating bone portions and other bone portions) in a sample of modern Colombian individuals. A set of 39 linear measurements was recorded from a sample of 100 individuals (47 females and 53 males aged between 20 and 74 and 18 and 77 years, respectively), which was used to create a reference sample database. A different subset of eight individuals (five females aged between 23 and 48 years, and three males aged between 27 and 43 years) was employed to randomly create six small-scale commingled assemblages for the purposes of testing the osteometric sorting models. Results demonstrate that this method has significant potential for use in the Colombian forensic context.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25608123','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25608123"><span>Control of diabetes and fibrinogen levels as well as improvement in health care might delay low cognitive performance in societies aging progressively.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lopes, Daniele Almeida; Moraes, Suzana Alves de; Freitas, Isabel Cristina Martins de</p> <p>2015-01-01</p> <p>To know the prevalence and factors associated to low cognitive performance in a representative sample of the adult population in a society aging progressively. Cross-sectional population-based study carried out in a three-stage sampling: 81 census tracts (primary sampling unity) were randomly selected, followed by 1,672 households and 2,471 participants (weighted sample) corresponding to the second and third stages, respectively. The outcome prevalence was calculated according sociodemographic, behavioral and health related variables. Crude and adjusted prevalence ratios were estimated using Poisson regression. The prevalence of low cognitive performance was high, mainly among females, and indicated linear trends into categories of age, schooling, income, plasma fibrinogen and self-reported health status. In multivariate models, gender, diabetes, fibrinogen and self-reported health status presented positive associations, while schooling, employment and sitting time presented negative associations with the outcome. Interventions related to diabetes and fibrinogen levels control as well as improvement in health care might delay low cognitive performance in societies aging progressively as such the study population.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=Cross+AND+fit&id=EJ1050387','ERIC'); return false;" href="https://eric.ed.gov/?q=Cross+AND+fit&id=EJ1050387"><span>A Transactional Analysis of the Relation between Maternal Sensitivity and Child Vagal Regulation</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Perry, Nicole B.; Mackler, Jennifer S.; Calkins, Susan D.; Keane, Susan P.</p> <p>2014-01-01</p> <p>A transactional model examining the longitudinal association between vagal regulation (as indexed by vagal withdrawal) and maternal sensitivity from age 2.5 to age 5.5 was assessed. The sample included 356 children (171 male, 185 female) and their mothers who participated in a laboratory visit at age 2.5, 4.5, and 5.5. Cardiac vagal tone was…</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li class="active"><span>10</span></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_10 --> <div id="page_11" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li class="active"><span>11</span></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="201"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21744059','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21744059"><span>Childhood social withdrawal, interpersonal impairment, and young adult depression: a mediational model.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Katz, Shaina J; Conway, Christopher C; Hammen, Constance L; Brennan, Patricia A; Najman, Jake M</p> <p>2011-11-01</p> <p>Building on interpersonal theories of depression, the current study sought to explore whether early childhood social withdrawal serves as a risk factor for depressive symptoms and diagnoses in young adulthood. The researchers hypothesized that social impairment at age 15 would mediate the association between social withdrawal at age 5 and depression by age 20. This mediational model was tested in a community sample of 702 Australian youth followed from mother's pregnancy to youth age 20. Structural equation modeling analyses found support for a model in which childhood social withdrawal predicted adolescent social impairment, which, in turn, predicted depression in young adulthood. Additionally, gender was found to moderate the relationship between adolescent social impairment and depression in early adulthood, with females exhibiting a stronger association between social functioning and depression at the symptom and diagnostic level. This study illuminates one potential pathway from early developing social difficulties to later depressive symptoms and disorders.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3384496','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3384496"><span>Childhood Social Withdrawal, Interpersonal Impairment, and Young Adult Depression: A Mediational Model</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Katz, Shaina J.; Conway, Christopher C.; Hammen, Constance L.; Brennan, Patricia A.; Najman, Jake M.</p> <p>2012-01-01</p> <p>Building on interpersonal theories of depression, the current study sought to explore whether early childhood social withdrawal serves as a risk factor for depressive symptoms and diagnoses in young adulthood. The researchers hypothesized that social impairment at age 15 would mediate the association between social withdrawal at age 5 and depression by age 20. This mediational model was tested in a community sample of 702 Australian youth followed from mother’s pregnancy to youth age 20. Structural equation modeling analyses found support for a model in which childhood social withdrawal predicted adolescent social impairment, which, in turn, predicted depression in young adulthood. Additionally, gender was found to moderate the relationship between adolescent social impairment and depression in early adulthood, with females exhibiting a stronger association between social functioning and depression at the symptom and diagnostic level. This study illuminates one potential pathway from early developing social difficulties to later depressive symptoms and disorders. PMID:21744059</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/20100003468','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20100003468"><span>An Approximately 4.35 Ga Ar-Ar Age for GRA 8 and the Complex Chronology of its Parent Body</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Park, J.; Nyquist, Laurence E.; Bogard, D. D.; Garrison, D. H.; Shih, C.-Y.; Reese, Y. D.</p> <p>2010-01-01</p> <p>GRA06128 and GRA06129 (hereafter GRA 8 and GRA 9) are partial melts of a parent body of approximately chondritic composition. We reported a conventional Sm-147-Nd-143 isochron age of 4.559+/-0.096 Ga and a 146 Sm-142Nd model age of 4.549+/-0.036 for combined data for the two rocks. Plagioclase plus whole rock and leachate (approx.phosphate) samples gave a secondary Sm-147-Nd-143 age of 3.4+/-0.4 Ga. An Ar-39-Ar-40 age of 4.460+/-0.028 Ga was interpreted as dating metamorphism in GRA 9. We report Ar-39-Ar-40 ages in the range approx.4344-4366 Ma for GRA 8, establishing similar but different Ar-39-Ar-40 ages for the two rocks, consistent with their different Sr-isotopic systematics, and discuss these ages in the context of the complex sequence of events that affected these samples.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/20100017380','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20100017380"><span>An Approximately 4.35 Ga Ar-Ar Age for GRA 8 and the Complex Chronology of its Parent Body</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Park, J.; Nyquist, L. E.; Bogard, D. D.; Garrison, D. H.; Shih, C.-Y.; Reese, Y. D.</p> <p>2010-01-01</p> <p>GRA06128 and GRA06129 (hereafter GRA 8 and GRA 9) are partial melts of a parent body of approximately chondritic composition. We reported a conventional SM-147Sm-ND_143 isochron age of 4.559 +/-.096 Ga and a SM-146-142Nd model age of 4.549 +/- 0.036 for combined data for the two rocks. Plagioclase plus whole rock and leachate (approximately phosphate) samples gave a secondary SM-147-ND-143 age of 3.4 +/-0.4 Ga. An Ar-39-Ar-40 age of 4.460+/-0.028 Ga was interpreted by as dating metamorphism in GRA 9. We report Ar-39-Ar-40 ages in the range approximately 4344-4366 Ma for GRA 8, establishing similar but different Ar-39-Ar-40 ages for the two rocks, consistent with their different Sr-istopic systematics, and discuss these ages in the context of the complex sequence of events that affected these samples</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ1162438.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ1162438.pdf"><span>Modeling Signal-Noise Processes Supports Student Construction of a Hierarchical Image of Sample</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Lehrer, Richard</p> <p>2017-01-01</p> <p>Grade 6 (modal age 11) students invented and revised models of the variability generated as each measured the perimeter of a table in their classroom. To construct models, students represented variability as a linear composite of true measure (signal) and multiple sources of random error. Students revised models by developing sampling…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012EGUGA..1411135B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012EGUGA..1411135B"><span>Early differentiation of the silicate Earth : new constraints from isotopic investigation of rocks from the lunar highlands</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Boyet, M.; Carlson, R.; Borg, L.; Connelly, J.; Horan, M.</p> <p>2012-04-01</p> <p>The isotopic similarity in O, Mo, W, Si, and Fe between lunar and terrestrial samples suggests that the two planetary bodies were equilibrated in the energetic aftermath of the giant impact that gave birth to the Moon [1]. Coupled 142Nd-143Nd isotope systematics of lunar samples including both low-Ti and high-Ti mare basalts along with KREEP basalts have been used to constrain the age of crystallization of the lunar interior [2-5]. These studies show that the Sm-Nd system in the lunar mantle closed in the interval of 180-250 Ma after the beginning of solar system formation, depending on the model considered for lunar mantle differentiation (1 or 2 stage-model and initial lunar Sm/Nd ratio). Does this age represent the age of Moon formation? A prolonged lunar magma ocean (LMO) might be expected given the insulating effect of the thick plagioclase crust, so closure of the Sm-Nd system in the lunar mantle, particularly in a late stage LMO component like KREEP, might substantially post-date lunar formation. We have recently determined a new age of 4360±3 Ma for the ferroan anorthosite (FAN) 60025 using the 207Pb-206Pb, 147Sm-143Nd and 146Sm-142Nd isotope systems [6]. This study is the first in which a single sample of FAN yielded consistent ages from multiple isotope dating techniques, strongly suggesting that this age indicates the time at which the sample crystallized. In order to pursue the question of whether Moon formation occurred over 100 Ma after solar system formation, we have investigated a number of lunar rocks sampling the highland crust from both the FAN and the Mg-suite groups. Internal Sm-Nd isochron on the norite 77215 yields an age of 4296±20 Ma, in agreement with the young age determined on 60025. We will show that our new data obtained on the 146Sm-142Nd systematics of the lunar crust support the scenario of a relative young age for the Moon. Thus, these results offer a unique opportunity to better constrain the composition of the terrestrial mantle at the time of the giant impact. Sm-Nd isotope data obtained on the oldest lunar samples will be modelled and compared to the different geochemical estimates proposed for the Hadean mantle composition coming from coupled 146,147Sm-142,143Nd isotope studies performed on both 4.3 Ga old samples from the Nuvvuagittuq greenstone belt [7] and 3.7 Ga old rocks from the Isua Supracrustal Belt [8-11]. [1] Pahlevan and Stevenson, 2007. EPSL 262, 438 ; [2] Nyquist et al., 1995. GCA 59, 2817 ; [3] Rankenburg et al., 2006. Science 312, 1369 ; [4] Boyet and Carlson, 2007. EPSL 262, 505 ; [5] Brandon et al., 2009. GCA 73, 6421 ; [6] Borg et al., 2011. Nature 477, 70 ; [7] O'Neil et al., 2008. Science 321, 1828 ; [8] Boyet et al., 2003. EPSL 214, 427 ; [9] Caro et al., 2003. Nature 423, 428 ; [10] Bennett et al., 2007. Science 318, 1907 ; [11] Rizo et al., EPSL 312, 267.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29781306','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29781306"><span>Assessment of Cognitively Stimulating Activity in a Spanish Population.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Morales Ortiz, Manuel; Fernández, Aaron</p> <p>2018-05-01</p> <p>Theoretical models of active ageing and cognitive reserve emphasize the importance of leading an active life to delay age-related cognitive deterioration and maintain good levels of well-being and personal satisfaction in the elderly. The objective of this research was to construct a scale to measure cognitively stimulating activities (CSA) in the Spanish language. The sample consisted of a total of 453 older persons. The scale was constructed from a list of 28 items and validated using structural equation models. The scale obtained showed a negative correlation with age and a positive correlation with education and physical activity. Using hierarchical regression models, CSAs were found to have a significant effect on attention when controlling for the effect of age and education. Likewise, a significant interaction between age and CSA was found on the measure of episodic memory. The validated CSA scale will enable the relationships between changes in cognitive functions and stimulating activities to be studied.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016AGUFM.V41D..02B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016AGUFM.V41D..02B"><span>The Age of the Moon</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Barboni, M.; Boehnke, P.; Keller, C. B.; Kohl, I. E.; McKeegan, K. D.; Schoene, B.; Young, E. D.</p> <p>2016-12-01</p> <p>Knowledge of the age of the Moon is important for understanding the early evolution of the solar system, including the timing of the hypothesized Giant Impact (GI). There have been many attempts to determine the Moon's age, but significant disagreement remains with some authors favoring an early formation and others arguing for a relatively young Moon formed at 4.4 Ga. Attempts to date the GI indirectly through its effects on the asteroid belt are problematic as there is no way to uniquely ascertain the cause of the observed disturbances (e.g., GI or meteorite parent body breakup). Determining the timing of the Lunar Magma Ocean (LMO) crystallization provides a more direct constraint on the age of the Moon, but interpreting the chronologic significance of LMO products is complicated by the fact that the only rock samples available are breccias. A better approach is to construct a model age for the fractional crystallization of the LMO since this should provide a global signature. Zircons from the Apollo samples are ancient, robust against later disturbances, and amenable to precise U-Pb geochronology and Hf isotope analyses that can be used to construct Lu-Hf model ages for the silicate differentiation of the Moon. Previous isotopic studies of Apollo zircons yielded artificially young Hf model ages because of the (then unknown) effect of neutron capture on Hf isotopic ratios generated by long exposure to cosmic radiation, and were unable to determine whether or not the U-Pb dates were concordant due to insufficient precision of in situ dating techniques. We have addressed these issues by carrying out CA-ID-TIMS U-Pb geochronology on Apollo 14 zircon fragments, followed by Hf isotope determination by solution MC-ICP-MS on the same volume of zircon. By constructing Hf model ages from zircons that are concordant to the sub-permil level, we show that the minimum age for the end of differentiation of the LMO, and by extension, the formation of the Moon, is 4.52 ± 0.01 Ga.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2002IAUS..187..195B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2002IAUS..187..195B"><span>Chemical evolution of the Magellanic Clouds</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Barbuy, B.; de Freitas Pacheco, J. A.; Idiart, T.</p> <p></p> <p>We have obtained integrated spectra for 14 clusters in the Magellanic Clouds, on which the spectral indices Hβ, Mg2, Fe5270, Fe5335 were measured. Selecting indices whose behaviour depends essentially on age and metallicity (Hβ and <Fe>), together with (B-V) and (V-K) colours, we were able to determine age and metallicities for these clusters, using calibrations based on single stellar population models (Borges et al. 1995). A chemical evolution model which follows a star formation history as indicated by the field population is checked with the age and metallicity data for our sample star clusters.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018SoSyR..52....1I','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018SoSyR..52....1I"><span>Size-Frequency Distribution of Small Lunar Craters: Widening with Degradation and Crater Lifetime</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Ivanov, B. A.</p> <p>2018-01-01</p> <p>The review and new measurements are presented for depth/diameter ratio and slope angle evolution during small ( D < 1 km) lunar impact craters aging (degradation). Comparative analysis of available data on the areal cratering density and on the crater degradation state for selected craters, dated with returned Apollo samples, in the first approximation confirms Neukum's chronological model. The uncertainty of crater retention age due to crater degradational widening is estimated. The collected and analyzed data are discussed to be used in the future updating of mechanical models for lunar crater aging.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27060589','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27060589"><span>Attrition analysed in five waves of a longitudinal yearly survey of smokers: findings from the ITC Netherlands survey.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Zethof, Dennis; Nagelhout, Gera E; de Rooij, Mark; Driezen, Pete; Fong, Geoffrey T; van den Putte, Bas; Hummel, Karin; de Vries, Hein; Thompson, Mary E; Willemsen, Marc C</p> <p>2016-08-01</p> <p>Attrition bias can affect the external validity of findings. This article analyses attrition bias and assesses the effectiveness of replenishment samples on demographic and smoking-related characteristics for the International Tobacco Control Netherlands Survey, a longitudinal survey among smokers. Attrition analyses were conducted for the first five survey waves (2008-12). We assessed, including and excluding replenishment samples, whether the demographic composition of the samples changed between the first and fifth waves. Replenishment samples were tailored to ensure the sample remained representative of the smoking population. We also constructed a multivariable survival model of attrition that included all five waves with replenishment samples. Of the original 1820 respondents recruited in 2008, 46% participated again in 2012. Demographic differences between waves due to attrition were generally small and replenishment samples tended to minimize them further. The multivariable survival analysis revealed that only two of the 10 variables analysed were significant predictors of attrition: a weak effect for gender (men dropped out more often) and weak to moderate effects for age (respondents aged 15-24 years dropped out more than aged 25-39 years, who dropped out more than those aged 40+ years). Weak to moderate attrition effects were found for men and younger age groups. This information could be used to minimize respondent attrition. Our findings suggest that sampling weights and tailored replenishment samples can effectively compensate for attrition effects. This is already being done for the International Tobacco Control Netherlands Survey, including the categories that significantly predicted attrition in this study. © The Author 2016. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5338118','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5338118"><span>Salivary caffeine concentrations are comparable to plasma concentrations in preterm infants receiving extended caffeine therapy</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Liu, Xiaoxi; Rhein, Lawrence M.; Darnall, Robert A.; Corwin, Michael J.; McEntire, Betty L.; Ward, Robert M.; James, Laura P.; Sherwin, Catherine M. T.; Heeren, Timothy C.; Hunt, Carl E.</p> <p>2016-01-01</p> <p>Aims Caffeine concentrations in preterm infants are usually measured in the blood. However, salivary assays may provide a valid and practical alternative. The present study explored the validity and clinical utility of salivary caffeine concentrations as an alternative to blood concentrations and developed a novel plasma/salivary caffeine distribution model. Methods Paired salivary and plasma samples were obtained in 29 infants. Salivary samples were obtained using a commercially available salivary collection system. Caffeine concentrations in the saliva and plasma were determined using high‐performance liquid chromatography. A population pharmacokinetic (PK) model was developed using NONMEM 7.3. Results The mean (± standard deviation) gestational age (GA) at birth and birth weight were 27.9 ± 2.1 weeks and 1171.6 ± 384.9 g, respectively. Paired samples were obtained at a mean postmenstrual age (PMA) of 35.5 ± 1.1 weeks. The range of plasma caffeine concentrations was 9.5–54.1 μg ml−1, with a mean difference (95% confidence interval) between plasma and salivary concentrations of −0.18 μg ml−1 (−1.90, 1.54). Salivary and plasma caffeine concentrations were strongly correlated (Pearson's correlation coefficient = 0.87, P < 0.001). Caffeine PK in plasma and saliva was simultaneously described by a three‐compartment recirculation model. Current body weight, birth weight, GA, PMA and postnatal age were not significantly correlated with any PK parameter. Conclusions Salivary sampling provides an easy, non‐invasive method for measuring caffeine concentrations. Salivary concentrations correlate highly with plasma concentrations. Caffeine PK in saliva and plasma are well described by a three‐compartment recirculation model. PMID:27145974</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24523247','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24523247"><span>Mortality, fertility, and the OY ratio in a model hunter-gatherer system.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>White, Andrew A</p> <p>2014-06-01</p> <p>An agent-based model (ABM) is used to explore how the ratio of old to young adults (the OY ratio) in a sample of dead individuals is related to aspects of mortality, fertility, and longevity experienced by the living population from which the sample was drawn. The ABM features representations of rules, behaviors, and constraints that affect person- and household-level decisions about marriage, reproduction, and infant mortality in hunter-gatherer systems. The demographic characteristics of the larger model system emerge through human-level interactions playing out in the context of "global" parameters that can be adjusted to produce a range of mortality and fertility conditions. Model data show a relationship between the OY ratios of living populations (the living OY ratio) and assemblages of dead individuals drawn from those populations (the dead OY ratio) that is consistent with that from empirically known ethnographic hunter-gatherer cases. The dead OY ratio is clearly related to the mean ages, mean adult mortality rates, and mean total fertility rates experienced by living populations in the model. Sample size exerts a strong effect on the accuracy with which the calculated dead OY ratio reflects the actual dead OY ratio of the complete assemblage. These results demonstrate that the dead OY ratio is a potentially useful metric for paleodemographic analysis of changes in mortality and mean age, and suggest that, in general, hunter-gatherer populations with higher mortality, higher fertility, and lower mean ages are characterized by lower dead OY ratios. Copyright © 2014 Wiley Periodicals, Inc.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27305100','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27305100"><span>The dimensionality of DSM5 alcohol use disorder in Puerto Rico.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Caetano, Raul; Vaeth, Patrice A C; Santiago, Katyana; Canino, Glorisa</p> <p>2016-11-01</p> <p>Test the dimensionality and measurement properties of lifetime DSM-5 AUD criteria in a sample of adults from the metropolitan area of San Juan, Puerto Rico. Cross-sectional study with survey data collected in 2013-2014. General population. Random household sample of the adult population 18 to 64years of age in San Juan, Puerto Rico (N=1510; lifetime drinker N=1107). DSM-5 alcohol use disorder (2 or more criteria present in 12months). Lifetime reports of AUD criteria were consistent with a one-dimensional model. Scalar measurement invariance was observed across gender, but measurement parameters for tolerance varied across age, with younger ages showing a lower threshold and steeper loading. Results provide support for a unidimensional DSM-5 AUD construct in a sample from a Latin American country. Copyright © 2016 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013AGUFM.T31D2538F','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013AGUFM.T31D2538F"><span>A closer look at 40Ar/39Ar systematics of illite, recoil, retention ages, total gas ages, and a new correction method</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Fitz-Diaz, E.; Hall, C. M.; van der Pluijm, B.</p> <p>2013-12-01</p> <p>One of the fundamentals of 40Ar-39Ar systematics of illite considers the effects of 39Ar recoil (ejection of 39Ar from tiny illite crystallites during the nuclear reaction 39K(n,p)39Ar), for which sample vacuum encapsulation prior to irradiation has been used since the 1990's. This technique separately measures the fraction of recoiled 39Ar and the Ar (39Ar and 40Ar) retained within illite crystals as they degas during step heating in vacuum. Total-gas ages (TGA) are calculated by using both recoiled and retained argon, while retention ages (RA) only involve retained Ar. Observations in numerous natural examples have shown that TGA fit stratigraphic constraints of geological processes when the average illite crystallite thickness (ICT) is smaller than 10nm, and that RA better matches these constrains for larger ICTs. Illite crystals with ICT >50nm show total gas and retention ages within a few My and they are identical, within analytical error, when ICT exceeds 150nm. We propose a new age correction that takes into account the average ICT and corresponding recoil for a sample , with such corrected ages (XCA) lying between the TGA and RA end-member ages. We apply this correction to samples containing one generation of illite and it particularly affects illite populations formed in the anchizone, with typical ICT values between 10-40nm. We analyzed bentonitic samples (S1, S2 and S3) from sites in Cretaceous carbonates in the front of the Monterrey salient in northern Mexico. Four size fractions (<0.05, 0.05-0.2, 0.2-1 & 1-2 μm) were separated, analyzed with XRD and dated by Ar-Ar. XRD analysis provides mineralogic characterization, illite polytype quantification, and illite crystallite thickness (ICT) determination using half-height peak width (illite crystallinity) and the Scherrer equation. All samples contain illite as the main mineral phase, ICT values between 8-27nm, from fine to coarser grain size fractions. Ages show a range in TGA among the different size fractions of S1, S2 and S3, respectively: 46-49, 36-43 and 40-52 My) and RA (54-64, 47-52 and 53-54 My. XCA calculations produce tighter constrained ranges (53-57, 45.5-48.5 and 49-52 My) with an overall average 51.1Ma×3.9 My. In the ICT vs. apparent age plot, authigenic illite grains show a greater slope that is in general slightly positive for TGA, slightly negative for RA, but close to zero for XCA. In the ICT vs. XCA plot thinner crystallites shows more dispersion than thicker ones. In order to test if such dispersion in the age of the finer/thinner illite is due to a different formation history in each site or the result of retention capability, degassing spectra were modeled for site XCA averages and overall XCA average. The modeling shows that local site ages best match the measured spectra, instead of a single age for the combined sites. The closeness between experimental and artificial degassing patterns also supports the hypothesis that each sample preserves a single age population. All illite grains in these samples grew progressively during folding in a time window that is constrained by the three sites. Small and large grains represent the same population in each sample, representing progressive degrees of grain growth (Ostwald ripening).</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/1015237','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/1015237"><span>Estimating stage-specific daily survival probabilities of nests when nest age is unknown</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Stanley, T.R.</p> <p>2004-01-01</p> <p>Estimation of daily survival probabilities of nests is common in studies of avian populations. Since the introduction of Mayfield's (1961, 1975) estimator, numerous models have been developed to relax Mayfield's assumptions and account for biologically important sources of variation. Stanley (2000) presented a model for estimating stage-specific (e.g. incubation stage, nestling stage) daily survival probabilities of nests that conditions on “nest type” and requires that nests be aged when they are found. Because aging nests typically requires handling the eggs, there may be situations where nests can not or should not be aged and the Stanley (2000) model will be inapplicable. Here, I present a model for estimating stage-specific daily survival probabilities that conditions on nest stage for active nests, thereby obviating the need to age nests when they are found. Specifically, I derive the maximum likelihood function for the model, evaluate the model's performance using Monte Carlo simulations, and provide software for estimating parameters (along with an example). For sample sizes as low as 50 nests, bias was small and confidence interval coverage was close to the nominal rate, especially when a reduced-parameter model was used for estimation.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26515013','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26515013"><span>Investigation of crimson-dyed fibres for a new approach on the characterization of cochineal and kermes dyes in historical textiles.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Serrano, Ana; van den Doel, Andre; van Bommel, Maarten; Hallett, Jessica; Joosten, Ineke; van den Berg, Klaas J</p> <p>2015-10-15</p> <p>The colorant behaviour of cochineal and kermes insect dyes in 141 experimentally-dyed and 28 artificially-aged samples of silk and wool was investigated using ultra-high performance liquid chromatography coupled to photodiode array detector (UHPLC-PDA), liquid chromatography electrospray ionisation mass spectrometry (LC-ESI-MS) and image scanning electron microscopy - energy dispersive X-ray spectroscopy (SEM-EDX). Partial-least squares discriminant analysis (PLS-DA) was then used to model the acquired UHPLC-PDA data and assess the possibility of discriminating cochineal insect species, as well as their correspondent dyed and aged reference fibres. The resulting models helped to characterize a set of 117 red samples from 95 historical textiles, in which UHPLC-PDA analyses have reported the presence of cochineal and kermes insect dyes. Analytical investigation of the experimentally-dyed and artificially-aged fibres has demonstrated that the ratio of compounds in the insects dye composition can change, depending on the dyeing conditions applied and the type of fibres used. Similarities were observed when comparing the UHPLC-MS and SEM-EDX results from the dyed and aged references with the historical samples. This was verified with PLS-DA models of the chromatographic data, facilitating the classification of the cochineal species present in the historical samples. The majority of these samples were identified to contain American cochineal, which is in agreement with historical and dye identification literature that describe the impact of this dyestuff into European and Asian dyeing practices, after the Iberian Expansion in the 16th century. The analytical results emphasize the importance of using statistical data interpretation for the discrimination of cochineal dyes, besides qualitative and quantitative evaluation of chromatograms. Hence, the combination of UHPLC-PDA with a statistical classification method, such as PLS-DA, has been demonstrated to be an advisable approach in future investigations to assess closely related species of natural dyes in historical textile samples. This is particularly important when aiming to achieve more accurate interpretations about the history of works of art, or the application of natural dyes in old textile production. Copyright © 2015 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2965047','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2965047"><span>Lack of assertion, peer victimization and risk for depression in girls: Testing a diathesis-stress model</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Keenan, Kate; Hipwell, Alison; Feng, Xin; Rischall, Michal; Henneberger, Angela; Klosterman, Susan</p> <p>2010-01-01</p> <p>Purpose To apply a diathesis × stress model to testing the association between peer victimization and depression in a sample of preadolescent girls. Methods DSM-IV symptoms of depression symptoms were measured at ages 9 and 11, assertiveness and peer victimization were assessed by youth report at age 9. Results The interaction of low levels of assertiveness and high peer victimization at age 9 was predictive of depression symptoms at age 11, controlling for earlier depression symptoms. Conclusions The results extend the literature on peer relations and depression by identifying a group of girls who may be particularly vulnerable to the stress of negative peer interactions. PMID:20970089</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011ECSS...92..534M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011ECSS...92..534M"><span>Otolith reading and multi-model inference for improved estimation of age and growth in the gilthead seabream Sparus aurata (L.)</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Mercier, Lény; Panfili, Jacques; Paillon, Christelle; N'diaye, Awa; Mouillot, David; Darnaude, Audrey M.</p> <p>2011-05-01</p> <p>Accurate knowledge of fish age and growth is crucial for species conservation and management of exploited marine stocks. In exploited species, age estimation based on otolith reading is routinely used for building growth curves that are used to implement fishery management models. However, the universal fit of the von Bertalanffy growth function (VBGF) on data from commercial landings can lead to uncertainty in growth parameter inference, preventing accurate comparison of growth-based history traits between fish populations. In the present paper, we used a comprehensive annual sample of wild gilthead seabream ( Sparus aurata L.) in the Gulf of Lions (France, NW Mediterranean) to test a methodology improving growth modelling for exploited fish populations. After validating the timing for otolith annual increment formation for all life stages, a comprehensive set of growth models (including VBGF) were fitted to the obtained age-length data, used as a whole or sub-divided between group 0 individuals and those coming from commercial landings (ages 1-6). Comparisons in growth model accuracy based on Akaike Information Criterion allowed assessment of the best model for each dataset and, when no model correctly fitted the data, a multi-model inference (MMI) based on model averaging was carried out. The results provided evidence that growth parameters inferred with VBGF must be used with high caution. Hence, VBGF turned to be among the less accurate for growth prediction irrespective of the dataset and its fit to the whole population, the juvenile or the adult datasets provided different growth parameters. The best models for growth prediction were the Tanaka model, for group 0 juveniles, and the MMI, for the older fish, confirming that growth differs substantially between juveniles and adults. All asymptotic models failed to correctly describe the growth of adult S. aurata, probably because of the poor representation of old individuals in the dataset. Multi-model inference associated with separate analysis of juveniles and adult fish is then advised to obtain objective estimations of growth parameters when sampling cannot be corrected towards older fish.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ926275.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ926275.pdf"><span>Validating the Mexican American Intergenerational Caregiving Model</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Escandon, Socorro</p> <p>2011-01-01</p> <p>The purpose of this study was to substantiate and further develop a previously formulated conceptual model of Role Acceptance in Mexican American family caregivers by exploring the theoretical strengths of the model. The sample consisted of women older than 21 years of age who self-identified as Hispanic, were related through consanguinal or…</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li class="active"><span>11</span></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_11 --> <div id="page_12" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li class="active"><span>12</span></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="221"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22596757-structural-transition-sputter-deposited-amorphous-germanium-films-aging-ambient-temperature','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22596757-structural-transition-sputter-deposited-amorphous-germanium-films-aging-ambient-temperature"><span>Structural transition in sputter-deposited amorphous germanium films by aging at ambient temperature</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Okugawa, M.; Nakamura, R., E-mail: nakamura@mtr.osakafu-u.ac.jp; Numakura, H.</p> <p></p> <p>The structure of amorphous Ge (a-Ge) films prepared by sputter-deposition and the effects of aging at ambient temperature and pressure were studied by pair-distribution-function (PDF) analysis from electron scattering and molecular dynamics simulations. The PDFs of the as-deposited and aged samples for 3–13 months showed that the major peaks for Ge-Ge bonds decrease in intensity and broaden with aging for up to 7 months. In the PDFs of a-Ge of molecular dynamics simulation obtained by quenching liquid at different rates, the major peak intensities of a slowly cooled model are higher than those of a rapidly cooled model. Analyses onmore » short- and medium-range configurations show that the slowly cooled model includes a certain amount of medium-range ordered (MRO) clusters, while the rapidly cooled model includes liquid-like configurations rather than MRO clusters. The similarity between experimental and computational PDFs implies that as-deposited films are similar in structure to the slowly cooled model, whereas the fully aged films are similar to the rapidly cooled model. It is assumed that as they undergo room-temperature aging, the MRO clusters disintegrate and transform into liquid-like regions in the same matrix. This transition in local configurations is discussed in terms of instability and the non-equilibrium of nanoclusters produced by a vapor-deposition process.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4980241','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4980241"><span>Visual Word Recognition Across the Adult Lifespan</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Cohen-Shikora, Emily R.; Balota, David A.</p> <p>2016-01-01</p> <p>The current study examines visual word recognition in a large sample (N = 148) across the adult lifespan and across a large set of stimuli (N = 1187) in three different lexical processing tasks (pronunciation, lexical decision, and animacy judgments). Although the focus of the present study is on the influence of word frequency, a diverse set of other variables are examined as the system ages and acquires more experience with language. Computational models and conceptual theories of visual word recognition and aging make differing predictions for age-related changes in the system. However, these have been difficult to assess because prior studies have produced inconsistent results, possibly due to sample differences, analytic procedures, and/or task-specific processes. The current study confronts these potential differences by using three different tasks, treating age and word variables as continuous, and exploring the influence of individual differences such as vocabulary, vision, and working memory. The primary finding is remarkable stability in the influence of a diverse set of variables on visual word recognition across the adult age spectrum. This pattern is discussed in reference to previous inconsistent findings in the literature and implications for current models of visual word recognition. PMID:27336629</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4490863','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4490863"><span>Depression and Delinquency Covariation in an Accelerated Longitudinal Sample of Adolescents</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Kofler, Michael J.; McCart, Michael R.; Zajac, Kristyn; Ruggiero, Kenneth J.; Saunders, Benjamin E.; Kilpatrick, Dean G.</p> <p>2015-01-01</p> <p>Objectives The current study tested opposing predictions stemming from the failure and acting out theories of depression-delinquency covariation. Methods Participants included a nationwide longitudinal sample of adolescents (N = 3,604) ages 12 to 17. Competing models were tested using cohort-sequential latent growth curve modeling to determine whether depressive symptoms at age 12 (baseline) predicted concurrent and age-related changes in delinquent behavior, whether the opposite pattern was apparent (delinquency predicting depression), and whether initial levels of depression predict changes in delinquency significantly better than vice versa. Results Early depressive symptoms predicted age-related changes in delinquent behavior significantly better than early delinquency predicted changes in depressive symptoms. In addition, the impact of gender on age-related changes in delinquent symptoms was mediated by gender differences in depressive symptom changes, indicating that depressive symptoms are a particularly salient risk factor for delinquent behavior in girls. Conclusion Early depressive symptoms represent a significant risk factor for later delinquent behavior – especially for girls – and appear to be a better predictor of later delinquency than early delinquency is of later depression. These findings provide support for the acting out theory and contradict failure theory predictions. PMID:21787049</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=NA&pg=2&id=EJ945306','ERIC'); return false;" href="https://eric.ed.gov/?q=NA&pg=2&id=EJ945306"><span>A Bifactor Model of Negative Affectivity: Fear and Distress Components among Younger and Older Youth</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Ebesutani, Chad; Smith, Ashley; Bernstein, Adam; Chorpita, Bruce F.; Higa-McMillan, Charmaine; Nakamura, Brad</p> <p>2011-01-01</p> <p>The Positive and Negative Affect Schedule for Children (PANAS-C) is a 27-item youth-report measure of positive affectivity and negative affectivity. Using 2 large school-age youth samples (clinic-referred sample: N = 662; school-based sample: N = 911), in the present study, we thoroughly examined the structure of the PANAS-C NA and PA scales and…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010AAS...21545501K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010AAS...21545501K"><span>Stochastic Sampling in the IMF of Galactic Open Clusters</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Kay, Christina; Hancock, M.; Canalizo, G.; Smith, B. J.; Giroux, M. L.</p> <p>2010-01-01</p> <p>We sought observational evidence of the effects of stochastic sampling of the initial mass function by investigating the integrated colors of a sample of Galactic open clusters. In particular we looked for scatter in the integrated (V-K) color as previous research resulted in little scatter in the (U-B) and (B-V) colors. Combining data from WEBDA and 2MASS we determined three different colors for 287 open clusters. Of these clusters, 39 have minimum uncertainties in age and formed a standard set. A plot of the (V-K) color versus age showed much more scatter than the (U-B) versus age. We also divided the sample into two groups based on a lowest luminosity limit which is a function of age and V magnitude. We expected the group of clusters fainter than this limit to show more scatter than the brighter group. Assuming the published ages, we compared the reddening corrected observed colors to those predicted by Starburst99. The presence of stochastic sampling should increase scatter in the distribution of the differences between observed and model colors of the fainter group relative to the brighter group. However, we found that K-S tests cannot rule out that the distribution of color difference for the brighter and fainter sets come from the same parent distribution. This indistinguishabilty may result from uncertainties in the parameters used to define the groups. This result constrains the size of the effects of stochastic sampling of the initial mass function.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22356782-core-halo-age-gradients-star-formation-orion-nebula-ngs-young-stellar-clusters','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22356782-core-halo-age-gradients-star-formation-orion-nebula-ngs-young-stellar-clusters"><span>Core-halo age gradients and star formation in the Orion Nebula and NGS 2024 young stellar clusters</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Getman, Konstantin V.; Feigelson, Eric D.; Kuhn, Michael A.</p> <p>2014-06-01</p> <p>We analyze age distributions of two nearby rich stellar clusters, the NGC 2024 (Flame Nebula) and Orion Nebula cluster (ONC) in the Orion molecular cloud complex. Our analysis is based on samples from the MYStIX survey and a new estimator of pre-main sequence (PMS) stellar ages, Age{sub JX} , derived from X-ray and near-infrared photometric data. To overcome the problem of uncertain individual ages and large spreads of age distributions for entire clusters, we compute median ages and their confidence intervals of stellar samples within annular subregions of the clusters. We find core-halo age gradients in both the NGC 2024more » cluster and ONC: PMS stars in cluster cores appear younger and thus were formed later than PMS stars in cluster peripheries. These findings are further supported by the spatial gradients in the disk fraction and K-band excess frequency. Our age analysis is based on Age{sub JX} estimates for PMS stars and is independent of any consideration of OB stars. The result has important implications for the formation of young stellar clusters. One basic implication is that clusters form slowly and the apparent age spreads in young stellar clusters, which are often controversial, are (at least in part) real. The result further implies that simple models where clusters form inside-out are incorrect and more complex models are needed. We provide several star formation scenarios that alone or in combination may lead to the observed core-halo age gradients.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24754365','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24754365"><span>Multigroup confirmatory factor analysis and structural invariance with age of the Behavior Rating Inventory of Executive Function (BRIEF)--French version.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Fournet, Nathalie; Roulin, Jean-Luc; Monnier, Catherine; Atzeni, Thierry; Cosnefroy, Olivier; Le Gall, Didier; Roy, Arnaud</p> <p>2015-01-01</p> <p>The parent and teacher forms of the French version of the Behavioral Rating Inventory of Executive Function (BRIEF) were used to evaluate executive function in everyday life in a large sample of healthy children (N = 951) aged between 5 and 18. Several psychometric methods were applied, with a view to providing clinicians with tools for score interpretation. The parent and teacher forms of the BRIEF were acceptably reliable. Demographic variables (such as age and gender) were found to influence the BRIEF scores. Confirmatory factor analysis was then used to test five competing models of the BRIEF's latent structure. Two of these models (a three-factor model and a two-factor model, both based on a nine-scale structure) had a good fit. However, structural invariance with age was only obtained with the two-factor model. The French version of the BRIEF provides a useful measure of everyday executive function and can be recommended for use in clinical research and practice.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24261921','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24261921"><span>Optimal dental age estimation practice in United Arab Emirates' children.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Altalie, Salem; Thevissen, Patrick; Fieuws, Steffen; Willems, Guy</p> <p>2014-03-01</p> <p>The aim of the study was to detect whether the Willems model, developed on a Belgian reference sample, can be used for age estimations in United Arab Emirates (UAE) children. Furthermore, it was verified that if added third molars development information in children provided more accurate age predictions. On 1900 panoramic radiographs, the development of left mandibular permanent teeth (PT) and third molars (TM) was registered according the Demirjian and the Kohler technique, respectively. The PT data were used to verify the Willems model and to develop a UAE model and to verify it. Multiple regression models with PT, TM, and PT + TM scores as independent and age as dependent factor were developed. Comparing the verified Willems- and the UAE model revealed differences in mean error of -0.01 year, mean absolute error of 0.01 year and root mean squared error of 0.90 year. Neglectable overall decrease in RMSE was detected combining PM and TM developmental information. © 2013 American Academy of Forensic Sciences.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20000081235&hterms=METAL+PRODUCTION&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3DMETAL%2BPRODUCTION','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20000081235&hterms=METAL+PRODUCTION&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3DMETAL%2BPRODUCTION"><span>Cosmogenic Ne-21 Production Rates in H-Chondrites Based on Cl-36 - Ar-36 Ages</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Leya, I.; Graf, Th.; Nishiizumi, K.; Guenther, D.; Wieler, R.</p> <p>2000-01-01</p> <p>We measured Ne-21 production rates in 14 H-chondrites in good agreement with model calculations. The production rates are based on Ne-21 concentrations measured on bulk samples or the non-magnetic fraction and Cl-36 - Ar-36 ages determined from the metal phase.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29242754','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29242754"><span>The Relationship Between Family, Parent, and Child Characteristics and Intimate-Partner Violence (IPV) Among Ukrainian Mothers.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Burlaka, Viktor; Grogan-Kaylor, Andrew; Savchuk, Olena; Graham-Bermann, Sandra A</p> <p>2017-07-01</p> <p>To assess the prevalence of intimate partner violence (IPV) in a sample of Ukrainian mothers of schoolchildren, and to examine the relationship between IPV and family, parent, and child characteristics utilizing multilevel models. Mothers of children aged 9-16 (n = 278, 93.5% Ukrainians) answered the Revised Conflict Tactics Scale (CTS2) assessing IPV. We also examined the relationship between IPV and maternal age, education, employment and marital status, family income, and rural or urban residence. Eighty-one percent of women reported psychological violence and 58% reported physical assault. On average, women reported 66 instances of IPV during the last year. Multilevel modeling revealed that lower maternal education, unemployment, not living with the husband or partner, and urban residency were associated with higher IPV victimization. Younger age and family income were not significantly related to IPV. IPV was a significant social problem in the present sample of Ukrainian mothers of school age children. Future policy and violence prevention programming should focus on supporting academic and employment opportunities for women, particularly for those living in urban areas.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2004SPIE.5469..197C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2004SPIE.5469..197C"><span>Spatial and mesoscopic fluctuations in glassy dynamics</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Chamon, Claudio C.; Cugliandolo, Leticia F.</p> <p>2004-05-01</p> <p>One of the striking properties of a glassy system is that many material properties depend on its age, i.e., the time since the system entered its glassy phase. In this this talk we shall review some recent progress (work in collaboration with H. E. Castillo, P. Charbonneau, J. L. Iguain, M. P. Kennett, D. R. Reichman and M. Sellitto) in understanding local aging, through the study of local observable quantities, which reveal that there are spatial heterogeneities and fluctuations in the aging process of macroscopic systems. We show that a number of universal properties are shared by many non-equilibrium systems, both with and without quenched disorder, such as the 3D Edwards-Anderson model and some kinetically constrained non-interacting 2D and 3D spin models, for example. Similar scaling relations are found for mesoscopic sample-to-sample fluctuations of global quantities in small size systems. We discuss how the emergence of a symmetry in aging systems, time-reparametrization invariance, could be responsible for the observed universal behavior of the local and mesoscopic non-equilibrium fluctuations.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26411790','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26411790"><span>Identity statuses and psychosocial functioning in Turkish youth: a person-centered approach.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Morsunbul, Umit; Crocetti, Elisabetta; Cok, Figen; Meeus, Wim</p> <p>2016-02-01</p> <p>In the present study, we tested whether the five identity statuses of the original Meeus-Crocetti model could be extracted in a Turkish sample. Their three-factor model of identity was used to examine identity formation. Participants were 1201 (59.6% females) youth aged between 12 and 24 years (Mage = 17.53 years, SDage = 3.25). Findings revealed that the five identity statuses extracted in previous studies (Crocetti, Rubini, Luyckx, & Meeus, 2008; Crocetti, Schwartz, Fermani, Klimstra, & Meeus, 2012) also emerged in a sample of Turkish adolescents and emerging adults. Findings indicated that gender and age affected the distribution of the individuals among the five identity statuses. Furthermore, individuals in the five identity statuses represented distinct profiles according to personality and self characteristics, problem behaviors and well-being, and interpersonal and group relationships. Finally, the status × age interactions indicated that the searching moratorium status became more problematic with age. Implications and suggestions for future research are also discussed. Copyright © 2015 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/20100023396','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20100023396"><span>Formation Ages of the Apollo 16 Regolith Breccias: Implications for Accessing the Bombardment History of the Moon</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Joy, K. H.; Kring, D. A.; Bogard, D. D.; Zolensky, M. E.; McKay, D. S.</p> <p>2010-01-01</p> <p>Regolith breccias are lithified samples of the regolith that have been fused together by impact shock and thermal metamorphism. In lunar regolith samples, the ratio of trapped 40Ar/36Ar is a useful indicator of antiquity and can be used to model the closure age/lifithication event of the regolith (i.e. the apparent time when Ar became trapped [1]), thus providing an important insight into specific times when that regolith was interacting with the the dynamic inner solar system space environment [2-4].</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22214429','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22214429"><span>Differences in physical fitness and gross motor coordination in boys aged 6-12 years specializing in one versus sampling more than one sport.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Fransen, Job; Pion, Johan; Vandendriessche, Joric; Vandorpe, Barbara; Vaeyens, Roel; Lenoir, Matthieu; Philippaerts, Renaat M</p> <p>2012-01-01</p> <p>The Developmental Model of Sports Participation proposes two pathways towards expertise in sports between 6 and 12 years of age: early specialization and early diversification. This study investigated the effect of sampling various sports and of spending many or few hours in sports on fitness and gross motor coordination. Altogether, 735 boys in three age groups (6-8, 8-10, and 10-12 years) were profiled using a fitness test battery. A computerized physical activity questionnaire was used to obtain data on sports participation. In the eldest group, (M)ANCOVA showed a positive effect of sampling various sports on strength, speed, endurance, and gross motor coordination (P < 0.05). A positive effect of many hours per week spent in sports was apparent in every age group. These data suggest an acute positive effect of many hours in sports and a latent positive effect of early sampling on fitness and gross motor coordination. Multiple comparisons revealed that boys aged 10-12 years, who spent many hours in various sports, performed better on standing broad jump (P < 0.05) and gross motor coordination (P < 0.05) than boys specializing in a single sport. Therefore, our results highlight the importance of spending many hours in sports and sampling various sports in the development of fitness and gross motor coordination.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70160133','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70160133"><span>Construction ages of the Upton Stone Chamber: Preliminary findings and suggestions for future luminescence research</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Mahan, Shannon; Martin, Frederick; Taylor, Cathy</p> <p>2015-01-01</p> <p>The Upton Chamber in Massachusetts, an earth-covered stone structure 3.4 meters (m) in diameter, with a corbelled stone dome, and a 4.3 m long entrance passageway, is studied with the aim of determining whether optically stimulated luminescence (OSL) dating methods can be used to establish the approximate construction date of the entranceway. Three samples, taken from soil behind the lowest stones in the wall of the entrance passageway, returned OSL ages between 385 and 660 years ago (or from 1625 A.D. to 1350 A.D.; using the year 2011 as the 0 year). One sample, taken below the bottom of the artifact layers in an archeological test pit in front of the chamber entrance, returned OSL ages between 650 and 880 years ago. A modern sample collected from a nearby fluvial channel returned an age between 55 and 175 years. The Upton Chamber OSL sampling results are challenging to interpret because there are mixtures in the samples of both younger and older grains that likely result from human modification, root or soil processes, animal bioturbation (i.e. ants and worms), and/or partial bleaching. The ages were determined using the lowest component of the finite mixture model as applied to a distribution of quartz grains. Further research may enable us to determine whether older components are of anthropomorphic or geological origin.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1266674-situ-monitoring-flow-permeable-surface-area-high-explosive-powder-using-small-sample-masses','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1266674-situ-monitoring-flow-permeable-surface-area-high-explosive-powder-using-small-sample-masses"><span>In-situ monitoring of flow-permeable surface area of high explosive powder using small sample masses</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a></p> <p>Maiti, Amitesh; Han, Yong; Zaka, Fowzia; ...</p> <p>2015-02-17</p> <p>To ensure good performance of high explosive devices over long periods of time, initiating powders need to maintain their specific surface area within allowed margins during the entire duration of deployment. A common diagnostic used in this context is the Fisher sub-sieve surface area (FSSA). Furthermore, commercial permeametry instruments measuring the FSSA requires the utilization of a sample mass equal to the crystal density of the sample material, an amount that is often one or two orders of magnitude larger than the typical masses found in standard detonator applications. Here we develop a customization of the standard device that canmore » utilize just tens of milligram samples, and with simple calibration yield FSSA values at ac curacy levels comparable to the standard apparatus. This necessitated a newly designed sample holder, made from a material of low coefficient of thermal expansion, which is conveniently transferred between an aging chamber and a re-designed permeametry tube. This improves the fidelity of accelerated aging studies by allowing measurement on the same physical sample at various time - instants during the aging process, and by obviating the need for a potentially FSSA-altering powder re-compaction step. We used the customized apparatus to monitor the FSSA evolution of a number of undoped and homolog-doped PETN powder samples that were subjected to artificial aging for several months at elevated temperatures. These results, in conjunction with an Arrhenius-based aging model were used to assess powder-coarsening - rates under long-term storage.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20040187257&hterms=Man&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D90%26Ntt%3DMan','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20040187257&hterms=Man&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D90%26Ntt%3DMan"><span>Changes in aerobic power of men, ages 25-70 yr</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Jackson, A. S.; Beard, E. F.; Wier, L. T.; Ross, R. M.; Stuteville, J. E.; Blair, S. N.</p> <p>1995-01-01</p> <p>This study quantified and compared the cross-sectional and longitudinal influence of age, self-report physical activity (SR-PA), and body composition (%fat) on the decline of maximal aerobic power (VO2peak). The cross-sectional sample consisted of 1,499 healthy men ages 25-70 yr. The 156 men of the longitudinal sample were from the same population and examined twice, the mean time between tests was 4.1 (+/- 1.2) yr. Peak oxygen uptake was determined by indirect calorimetry during a maximal treadmill exercise test. The zero-order correlations between VO2peak and %fat (r = -0.62) and SR-PA (r = 0.58) were significantly (P < 0.05) higher that the age correlation (r = -0.45). Linear regression defined the cross-sectional age-related decline in VO2peak at 0.46 ml.kg-1.min-1.yr-1. Multiple regression analysis (R = 0.79) showed that nearly 50% of this cross-sectional decline was due to %fat and SR-PA, adding these lifestyle variables to the multiple regression model reduced the age regression weight to -0.26 ml.kg-1.min-1.yr-1. Statistically controlling for time differences between tests, general linear models analysis showed that longitudinal changes in aerobic power were due to independent changes in %fat and SR-PA, confirming the cross-sectional results.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4651490','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4651490"><span>The Effect of Novel Research Activities on Long-term Survival of Temporarily Captive Steller Sea Lions (Eumetopias jubatus)</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Shuert, Courtney; Horning, Markus; Mellish, Jo-Ann</p> <p>2015-01-01</p> <p>Two novel research approaches were developed to facilitate controlled access to, and long-term monitoring of, juvenile Steller sea lions for periods longer than typically afforded by traditional fieldwork. The Transient Juvenile Steller sea lion Project at the Alaska SeaLife Center facilitated nutritional, physiological, and behavioral studies on the platform of temporary captivity. Temporarily captive sea lions (TJs, n = 35) were studied, and were intraperitoneally implanted with Life History Transmitters (LHX tags) to determine causes of mortality post-release. Our goal was to evaluate the potential for long-term impacts of temporary captivity and telemetry implants on the survival of study individuals. A simple open-population Cormack-Jolly-Seber mark-recapture model was built in program MARK, incorporating resightings of uniquely branded study individuals gathered by several contributing institutions. A priori models were developed to weigh the evidence of effects of experimental treatment on survival with covariates of sex, age, capture age, cohort, and age class. We compared survival of experimental treatment to a control group of n = 27 free-ranging animals (FRs) that were sampled during capture events and immediately released. Sex has previously been show to differentially affect juvenile survival in Steller sea lions. Therefore, sex was included in all models to account for unbalanced sex ratios within the experimental group. Considerable support was identified for the effects of sex, accounting for over 71% of total weight for all a priori models with delta AICc <5, and over 91% of model weight after removal of pretending variables. Overall, most support was found for the most parsimonious model based on sex and excluding experimental treatment. Models including experimental treatment were not supported after post-hoc considerations of model selection criteria. However, given the limited sample size, alternate models including effects of experimental treatments remain possible and effects may yet become apparent in larger sample sizes. PMID:26580549</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22494723-improved-model-estimate-trapping-parameters-polymeric-materials-its-application-normal-aged-low-density-polyethylenes','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22494723-improved-model-estimate-trapping-parameters-polymeric-materials-its-application-normal-aged-low-density-polyethylenes"><span>An improved model to estimate trapping parameters in polymeric materials and its application on normal and aged low-density polyethylenes</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Liu, Ning, E-mail: nl4g12@soton.ac.uk; He, Miao; Alghamdi, Hisham</p> <p>2015-08-14</p> <p>Trapping parameters can be considered as one of the important attributes to describe polymeric materials. In the present paper, a more accurate charge dynamics model has been developed, which takes account of charge dynamics in both volts-on and off stage into simulation. By fitting with measured charge data with the highest R-square value, trapping parameters together with injection barrier of both normal and aged low-density polyethylene samples were estimated using the improved model. The results show that, after long-term ageing process, the injection barriers of both electrons and holes is lowered, overall trap depth is shallower, and trap density becomesmore » much greater. Additionally, the changes in parameters for electrons are more sensitive than those of holes after ageing.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18371674','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18371674"><span>Three-way principal component analysis of the volatile fraction by HS-SPME/GC of aceto balsamico tradizionale of modena.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Cocchi, Marina; Durante, Caterina; Grandi, Margherita; Manzini, Daniela; Marchetti, Andrea</p> <p>2008-01-15</p> <p>The present research is aimed at monitoring the evolution of the volatile organic compounds of different samples of aceto balsamico tradizionale of modena (ABTM) during ageing. The flavouring compounds, headspace fraction, of the vinegars of four batterie were sampled by solid phase microextraction technique (SPME), and successively analysed by gas chromatography. Obtaining a data set characterized by different sources of variability such as, different producers, samples of different age and chromatographic profile. The gas chromatographic signals were processed by a three-way data analysis method (Tucker3), which allows an easy visualisation of the data by furnishing a distinct set of graphs for each source of variability. The obtained results indicate that the samples can be separated according to their age highlighting the chemical constituents, which play a major role for their differentiation. The present study represents an example of how the application of Tucker3 models, on gas chromatographic signals may help to follow the transformation processes of food products.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li class="active"><span>12</span></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_12 --> <div id="page_13" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li class="active"><span>13</span></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="241"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26055263','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26055263"><span>Exploring the Relationship between Family Functioning and Psycho-Pathology in a Sample in the Pediatric Age.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Pepe, Silvia; Tortolani, Daniela; Gentile, Simonetta; Di Ciommo, Vincenzo M</p> <p>2015-03-17</p> <p>The purpose of this study was to investigate differences in family functioning between families with clinical subjects in paediatric age and families taken from the Italian population. To this aim we used the Family Adaptability and Cohesion Evaluation Scale (FACES). Participants were children diagnosed with a psychopathology, recruited into the psychiatry department in a Paediatric Hospital of Rome. A total of 106 families participated in the study. The non-pathological sample is composed by 2,543 parents in different age periods of the life-cycle. Results showed significant differences in family functioning between pathological and non-pathological samples. Specifically, families from the pathological sample (particularly the ones who experienced eating disorders) were more frequently located in extreme or mid-range regions of Olson's circumplex model (p < .001). These findings suggest some considerations that can be useful in therapeutic works with families in a clinical setting. Critical aspects and clinical applications are discussed.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15331863','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15331863"><span>Assessing competence: the European Survey on Aging Protocol (ESAP).</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Fernández-Ballesteros, Rocío; Zamarrón, María Dolores; Rudinger, Georg; Schroots, Johannes J F; Hekkinnen, Eino; Drusini, Andrea; Paul, Constanza; Charzewska, Jadwiga; Rosenmayr, Leopold</p> <p>2004-01-01</p> <p>The main goal of this research project was to translate and adapt the European Survey on Ageing Protocol (ESAP) to 7 European countries/cultures. This article presents preliminary results from the ESAP, the basic assessment instrument of EXCELSA (European Longitudinal Study of Aging). 672 individuals aged 30-85, selected through quota sampling (by age, gender, education and living conditions), participated in this study, with 96 subjects from each of the 7 European countries. The basic research protocol for assessing competence and its determinants was designed to be administered in a 90-min in-home face-to-face interview. It contains a series of questions, instruments, scales and physical tests assessing social relationships and caregiving, mental abilities, well-being, personality, mastery and perceived control, self-reported health, lifestyles, anthropometry, biobehavioral measures and sociodemographic variables. 84% of ESAP measures are age-dependent and 75% of them discriminate between education levels. Minor differences were found due to gender, and between people living in rural and urban areas. Exploratory factor analysis yielded 10 factors accounting for 67.85% of total variance, one of which was identified as cognitive and physical 'competence'. This factorial structure was tested across countries through concordance coefficients. Finally, using structural equation modeling, our data were fitted into a model of competence. When the sample was split into younger groups (aged 30-49 years) and older ones (50 and more years), the same model was appropriate for our data. The results are discussed in accordance with other findings on psychosocial, biophysical and sociodemographic components of competence, and also in accordance with theories on competence and successful aging. Copyright 2004 S. Karger AG, Basel</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24631001','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24631001"><span>General and substance-specific predictors of young adult nicotine dependence, alcohol use disorder, and problem behavior: replication in two samples.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bailey, J A; Samek, D R; Keyes, M A; Hill, K G; Hicks, B M; McGue, M; Iacono, W G; Epstein, M; Catalano, R F; Haggerty, K P; Hawkins, J D</p> <p>2014-05-01</p> <p>This paper presents two replications of a heuristic model for measuring environment in studies of gene-environment interplay in the etiology of young adult problem behaviors. Data were drawn from two longitudinal, U.S. studies of the etiology of substance use and related behaviors: the Raising Healthy Children study (RHC; N=1040, 47% female) and the Minnesota Twin Family Study (MTFS; N=1512, 50% female). RHC included a Pacific Northwest, school-based, community sample. MTFS included twins identified from state birth records in Minnesota. Both studies included commensurate measures of general family environment and family substance-specific environments in adolescence (RHC ages 10-18; MTFS age 18), as well as young adult nicotine dependence, alcohol and illicit drug use disorders, HIV sexual risk behavior, and antisocial behavior (RHC ages 24, 25; MTFS age 25). Results from the two samples were highly consistent and largely supported the heuristic model proposed by Bailey et al. (2011). Adolescent general family environment, family smoking environment, and family drinking environment predicted shared variance in problem behaviors in young adulthood. Family smoking environment predicted unique variance in young adult nicotine dependence. Family drinking environment did not appear to predict unique variance in young adult alcohol use disorder. Organizing environmental predictors and outcomes into general and substance-specific measures provides a useful way forward in modeling complex environments and phenotypes. Results suggest that programs aimed at preventing young adult problem behaviors should target general family environment and family smoking and drinking environments in adolescence. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4310214','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4310214"><span>Influence of Gestational Age and Body Weight on the Pharmacokinetics of Labetalol in Pregnancy</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Fischer, James H.; Sarto, Gloria E.; Hardman, Jennifer; Endres, Loraine; Jenkins, Thomas M.; Kilpatrick, Sarah J.; Jeong, Hyunyoung; Geller, Stacie; Deyo, Kelly; Fischer, Patricia A.; Rodvold, Keith A.</p> <p>2015-01-01</p> <p>Background and Objectives Labetalol is frequently prescribed for treatment of hypertension during pregnancy. However, the influence of pregnancy on labetalol pharmacokinetics is uncertain, with inconsistent findings reported by previous studies. This study examined the population pharmacokinetics of oral labetalol during and after pregnancy in women receiving labetalol for hypertension. Methods Data were collected from 57 women receiving the drug for hypertension from the 12th week of pregnancy through 12 weeks postpartum using a prospective, longitudinal design. A sparse sampling strategy guided collection of plasma samples. Samples were assayed for labetalol by high performance liquid chromatography. Estimation of population pharmacokinetic parameters and covariate effects was performed by nonlinear mixed effects modeling using NONMEM. Final population model was validated by bootstrap analysis and visual predictive check. Simulations were performed with the final model to evaluate the appropriate body weight to guide labetalol dosing. Results Lean body weight (LBW) and gestational age, i.e., weeks of pregnancy, were identified as significantly influencing oral clearance (CL/F) of labetalol, with CL/F ranging from 1.4-fold greater than postpartum values at 12 weeks gestational age to 1.6-fold greater at 40 weeks. Doses adjusted for LBW provide more consistent drug exposure than doses adjusted for total body weight. The apparent volumes of distribution for the central compartment and at steady-state were 1.9-fold higher during pregnancy. Conclusions Gestational age and LBW impact the pharmacokinetics of labetalol during pregnancy and have clinical implications for adjusting labetalol doses in these women. PMID:24297680</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26362216','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26362216"><span>Red blood cells open promising avenues for longitudinal studies of ageing in laboratory, non-model and wild animals.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Stier, Antoine; Reichert, Sophie; Criscuolo, Francois; Bize, Pierre</p> <p>2015-11-01</p> <p>Ageing is characterized by a progressive deterioration of multiple physiological and molecular pathways, which impair organismal performance and increase risks of death with advancing age. Hence, ageing studies must identify physiological and molecular pathways that show signs of age-related deterioration, and test their association with the risk of death and longevity. This approach necessitates longitudinal sampling of the same individuals, and therefore requires a minimally invasive sampling technique that provides access to the larger spectrum of physiological and molecular pathways that are putatively associated with ageing. The present paper underlines the interest in using red blood cells (RBCs) as a promising target for longitudinal studies of ageing in vertebrates. RBCs provide valuable information on the following six pathways: cell maintenance and turnover (RBC number, size, and heterogeneity), glucose homeostasis (RBC glycated haemoglobin), oxidative stress parameters, membrane composition and integrity, mitochondrial functioning, and telomere dynamics. The last two pathways are specific to RBCs of non-mammalian species, which possess a nucleus and functional mitochondria. We present the current knowledge about RBCs and age-dependent changes in these pathways in non-model and wild species that are especially suitable to address questions related to ageing using longitudinal studies. We discuss how the different pathways relate with survival and lifespan and give information on their genetic and environmental determinants to appraise their evolutionary potential. Copyright © 2015 Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/4056331','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/4056331"><span>Relationships among abilities in elderly adults: a time lag analysis.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hayslip, B; Brookshire, R G</p> <p>1985-11-01</p> <p>Previous research has suggested that relationships among primary abilities said to measure crystallized (Gc) and fluid (Gf) intelligences remain the same across cohorts if age is held constant, despite generational changes in the levels of abilities. The present study assessed differences in relationship among several components of Gf/Gc in two independent samples of elderly adults, tested in 1975 and 1979 by the same investigator. The 1975 sample consisted of 54 elderly adults aged 59 to 76 years (M = 67.7); the 1979 sample of 50 elderly adults was aged 55 to 82 (M = 69.4). Time-lagged differences in relationships among abilities measuring Gf and Gc (induction, figural relations, and verbal comprehension) were investigated using confirmatory factor analytic procedures. Although a two factor (Gf, Gc) model was common to both the 1975 and 1979 samples, significant differences in unique variances were observed across samples. Some, albeit weaker, evidence was found suggesting time-lagged differences in factor covariances. These data, for the most part, support previous research with younger individuals, suggesting consistency in factor structure across time and cohort.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25645903','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25645903"><span>Bayesian calibration for forensic age estimation.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ferrante, Luigi; Skrami, Edlira; Gesuita, Rosaria; Cameriere, Roberto</p> <p>2015-05-10</p> <p>Forensic medicine is increasingly called upon to assess the age of individuals. Forensic age estimation is mostly required in relation to illegal immigration and identification of bodies or skeletal remains. A variety of age estimation methods are based on dental samples and use of regression models, where the age of an individual is predicted by morphological tooth changes that take place over time. From the medico-legal point of view, regression models, with age as the dependent random variable entail that age tends to be overestimated in the young and underestimated in the old. To overcome this bias, we describe a new full Bayesian calibration method (asymmetric Laplace Bayesian calibration) for forensic age estimation that uses asymmetric Laplace distribution as the probability model. The method was compared with three existing approaches (two Bayesian and a classical method) using simulated data. Although its accuracy was comparable with that of the other methods, the asymmetric Laplace Bayesian calibration appears to be significantly more reliable and robust in case of misspecification of the probability model. The proposed method was also applied to a real dataset of values of the pulp chamber of the right lower premolar measured on x-ray scans of individuals of known age. Copyright © 2015 John Wiley & Sons, Ltd.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/5115285','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/5115285"><span>Generalized fish life-cycle poplulation model and computer program</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>DeAngelis, D. L.; Van Winkle, W.; Christensen, S. W.</p> <p>1978-03-01</p> <p>A generalized fish life-cycle population model and computer program have been prepared to evaluate the long-term effect of changes in mortality in age class 0. The general question concerns what happens to a fishery when density-independent sources of mortality are introduced that act on age class 0, particularly entrainment and impingement at power plants. This paper discusses the model formulation and computer program, including sample results. The population model consists of a system of difference equations involving age-dependent fecundity and survival. The fecundity for each age class is assumed to be a function of both the fraction of females sexuallymore » mature and the weight of females as they enter each age class. Natural mortality for age classes 1 and older is assumed to be independent of population size. Fishing mortality is assumed to vary with the number and weight of fish available to the fishery. Age class 0 is divided into six life stages. The probability of survival for age class 0 is estimated considering both density-independent mortality (natural and power plant) and density-dependent mortality for each life stage. Two types of density-dependent mortality are included. These are cannibalism of each life stage by older age classes and intra-life-stage competition.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/1339898-towards-aging-mechanisms-cross-linked-polyethylene-xlpe-cable-insulation-materials-nuclear-power-plants','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/1339898-towards-aging-mechanisms-cross-linked-polyethylene-xlpe-cable-insulation-materials-nuclear-power-plants"><span>Towards aging mechanisms of cross-linked polyethylene (XLPE) cable insulation materials in nuclear power plants</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Liu, Shuaishuai; Fifield, Leonard S.; Bowler, Nicola</p> <p></p> <p>Cross-linked polyethylene (XLPE) cable insulation material undergoes simultaneous, accelerated thermal and gamma-radiation aging to simulate the long-term aging environment within nuclear power plants (NPPs). A variety of materials characterization tests, including scanning electron microscopy, thermo-gravimetric analysis, differential scanning calorimetry, oxidation induction time, gel-fraction and dielectric properties measurement, are conducted on pristine and differently aged XLPE samples. A preliminary model of one possible aging mechanism of XLPE cable insulation material under gamma radiation at elevated temperature of 115 °C is suggested.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28412835','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28412835"><span>Validation of a Seven-Factor Structure for the Motives for Playing Drinking Games Measure.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Zamboanga, Byron L; Audley, Shannon; Olthuis, Janine V; Blumenthal, Heidemarie; Tomaso, Cara C; Bui, Ngoc; Borsari, Brian</p> <p>2017-04-01</p> <p>Playing drinking games can be characterized as a high-risk drinking activity because games are typically designed to promote heavy alcohol consumption. While research suggests that young adults are motivated to play drinking games for a variety of reasons (e.g., for thrills/fun, for the competition), the Motives for Playing Drinking Games measure has received limited empirical attention. We examined the psychometric properties of this measure with a confirmation sample of young adults recruited from Amazon's MTurk ( N = 1,809, ages 18-25 years, 47% men; 41% not currently enrolled in college) and a validation sample of college students ( N = 671; ages 18-23 years; 26% men). Contrary to the 8-factor model obtained by Johnson and Sheets in a study published in 2004, examination of the factor structure with our confirmation sample yielded a revised 7-factor model that was invariant across race/ethnicity and college student status. This model was also validated with the college student sample. In the confirmation sample, enhancement/thrills and sexual pursuit motives for playing drinking games were positively associated with gaming frequency/consumption and negative gaming consequences. Furthermore, conformity motives for playing drinking games were positively associated with negative gaming consequences, while competition motives were positively associated with gaming frequency. These findings have significant implications for research and prevention/intervention efforts.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2006SPIE.6381E..09Y','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2006SPIE.6381E..09Y"><span>Age determination of bottled Chinese rice wine by VIS-NIR spectroscopy</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Yu, Haiyan; Lin, Tao; Ying, Yibin; Pan, Xingxiang</p> <p>2006-10-01</p> <p>The feasibility of non-invasive visible and near infrared (VIS-NIR) spectroscopy for determining wine age (1, 2, 3, 4, and 5 years) of Chinese rice wine was investigated. Samples of Chinese rice wine were analyzed in 600 mL square brown glass bottles with side length of approximately 64 mm at room temperature. VIS-NIR spectra of 100 bottled Chinese rice wine samples were collected in transmission mode in the wavelength range of 350-1200 nm by a fiber spectrometer system. Discriminant models were developed based on discriminant analysis (DA) together with raw, first and second derivative spectra. The concentration of alcoholic degree, total acid, and °Brix was determined to validate the NIR results. The calibration result for raw spectra was better than that for first and second derivative spectra. The percentage of samples correctly classified for raw spectra was 98%. For 1-, 2-, and 3-year-old sample groups, the sample were all correctly classified, and for 4- and 5-year-old sample groups, the percentage of samples correctly classified was 92.9%, respectively. In validation analysis, the percentage of samples correctly classified was 100%. The results demonstrated that VIS-NIR spectroscopic technique could be used as a non-invasive, rapid and reliable method for predicting wine age of bottled Chinese rice wine.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/20170001711','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20170001711"><span>Interpretation of Ferroan Anorthosite Ages and Implications for the Lunar Magma Ocean</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Neal, C. R.; Draper, D. S.</p> <p>2017-01-01</p> <p>Ferroan Anorthosites (FANs) are considered to have purportedly crystallized directly from the lunar magma ocean (LMO) as a flotation crust. LMO modeling suggests that such anorthosites started to form only after greater than 70 percent of the LMO had crystallized. Recent age dates for FANs have questioned this hypothesis as they span too large of an age range. This means a younger age for the Moon-forming giant impact or the LMO hypothesis is flawed. However, FANs are notoriously difficult to age-date using the isochron method. We have proposed a mechanism for testing the LMO hypothesis through using plagioclase trace element abundances to calculate equilibrium liquids and compare them with LMO crystallization models. We now examine the petrography of the samples that have Sm-Nd (Samarium-Neodymium) age dates (Rb-Sr (Rubidium-Strontium) isotopic systematics may have been disturbed) and propose a relative way to age date FANs.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70173571','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70173571"><span>Factors influencing recruitment of walleye and white bass to three distinct early ontogenetic stages</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>DeBoer, Jason A.; Pope, Kevin L.</p> <p>2015-01-01</p> <p>Determining the factors that influence recruitment to sequential ontogenetic stages is critical for understanding recruitment dynamics of fish and for effective management of sportfish, particularly in dynamic and unpredictable environments. We sampled walleye (Sander vitreus) and white bass (Morone chrysops) at 3 ontogenetic stages (age 0 during spring: ‘age-0 larval’; age 0 during autumn: ‘age-0 juvenile’; and age 1 during autumn: ‘age-1 juvenile’) from 3 reservoirs. We developed multiple linear regression models to describe factors influencing age-0 larval, age-0 juvenile and age-1 juvenile walleye and white bass abundance indices. Our models explained 40–80% (68 ± 9%; mean ± SE) and 71%–97% (81 ± 6%) of the variability in catch for walleye and white bass respectively. For walleye, gizzard shad were present in the candidate model sets for all three ontogenetic stages we assessed. For white bass, there was no unifying variable in all three stage-specific candidate model sets, although walleye abundance was present in two of the three white bass candidate model sets. We were able to determine several factors affecting walleye and white bass year-class strength at multiple ontogenetic stages; comprehensive analyses of factors influencing recruitment to multiple early ontogenetic stages are seemingly rare in the literature. Our models demonstrate the interdependency among early ontogenetic stages and the complexities involved with sportfish recruitment.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=international+AND+relations+AND+quarterly&pg=2&id=EJ820944','ERIC'); return false;" href="https://eric.ed.gov/?q=international+AND+relations+AND+quarterly&pg=2&id=EJ820944"><span>Antisocial Behavior and Depressive Symptoms: Longitudinal and Concurrent Relations</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Vieno, Alessio; Kiesner, Jeff; Pastore, Massimiliano; Santinello, Massimo</p> <p>2008-01-01</p> <p>The relations between antisocial behavior and depressive symptoms were examined both longitudinally and concurrently in a sample of Italian early-adolescents. Structural equation modelling was applied to 10-month longitudinal data from a sample of 107 youths (54 girls; mean age at baseline = M = 12.5). Early adolescents completed a questionnaire…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/9426790','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/9426790"><span>Reasons for quitting: intrinsic and extrinsic motivation for smoking cessation in a population-based sample of smokers.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Curry, S J; Grothaus, L; McBride, C</p> <p>1997-01-01</p> <p>An intrinsic-extrinsic model of motivation for smoking cessation is extended to a population-based sample of smokers (N = 1,137), using a previously validated Reasons for Quitting (RFQ) scale. Psychometric evaluation of the RFQ replicated the model that includes health concerns and self-control as intrinsic motivation dimensions and immediate reinforcement and social influence as extrinsic motivation dimensions. Compared to volunteers, the population-based sample of smokers reported equivalent health concerns, lower self-control, and higher social influence motivation for cessation. Within the population-based sample, women compared to men were less motivated to quit by health concerns and more motivated by immediate reinforcement; smokers above age 55 expressed lower health concerns and higher self-control motivation than smokers below age 55. Higher baseline levels of intrinsic relative to extrinsic motivation were associated with more advanced stages of readiness to quit smoking and successful smoking cessation at a 12-month follow-up. Among continuing smokers, improvement in stage of readiness to quit over time was associated with significant increases in health concerns and self-control motivation.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28269352','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28269352"><span>Fall risk factors analysis based on sample entropy of plantar kinematic signal during stance phase.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Shengyun Liang; Huiyu Jia; Zilong Li; Huiqi Li; Xing Gao; Zuchang Ma; Yingnan Ma; Guoru Zhao</p> <p>2016-08-01</p> <p>Falls are a multi-causal phenomenon with a complex interaction. The aim of our research is to study the effect of multiple variables for potential risk of falls and construct an elderly fall risk assessment model based on demographics data and gait characteristics. A total of 101 subjects, whom belong to Malianwa Street, aged above 50 years old and participated in questionnaire survey. Participants were classified into three groups (high, medium and low risk group) according to the score of elderly fall risk assessment scale. In addition, the data of ground reaction force (GRF) and ground reaction moment (GRM) was record when they performed walking at comfortable state. The demographic variables, sample entropy of GRF and GRM, and impulse difference of bilateral foot were considered as potential explanatory variables of risk assessment model. Firstly, we investigated whether different groups could present difference in every variable. Statistical differences were found for the following variables: age (p=2.28e-05); impulse difference (p=0.02036); sample entropy of GRF in vertical direction (p=0.0144); sample entropy of GRM in anterior-posterior direction (p=0.0387). Finally, the multiple regression analysis results indicated that age, impulse difference and sample entropy of resultant GRM could identify individuals who had different levels of fall risk. Therefore, those results could potentially be useful in the fall risk assessment and monitor the state of physical function in elderly population.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29751984','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29751984"><span>Age-related trajectories of social cognition in youth at clinical high risk for psychosis: An exploratory study.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Davidson, Charlie A; Piskulic, Danijela; Addington, Jean; Cadenhead, Kristen S; Cannon, Tyrone D; Cornblatt, Barbara A; McGlashan, Thomas H; Perkins, Diana O; Seidman, Larry J; Tsuang, Ming T; Walker, Elaine F; Bearden, Carrie E; Mathalon, Daniel H; Woods, Scott W; Johannesen, Jason K</p> <p>2018-05-08</p> <p>Clinical high risk (CHR) status is characterized by impairments in social cognition, but questions remain concerning their stability over development. In cross-sectional analysis of a large naturalistic sample, the current study examined whether those at CHR status show deviant trajectories for age-related change in social cognitive ability, and whether these trajectories are influenced by treatment history. Emotion perception (EP) and theory of mind (ToM) were assessed in 675 CHR and 263 healthy comparison (HC) participants aged 12-35. Age effects in CHR were modeled against HC age-expected performance. Prior medication status was tested for interactions with age. CHR exhibited normal age trajectory for EP, but significantly lower slopes for ToM from age 17 onward. This effect was specific to stimuli exhibiting sarcasm and not to detection of lies. When treatment history was included in the model, age-trajectory appeared normal in CHR subjects previously prescribed both antipsychotics and antidepressant medication, although the blunted trajectory still characterized 80% of the sample. Cross-sectional analyses suggested that blunting of ToM in CHR develops in adolescence, while EP abilities were diminished evenly across the age range. Exploratory analyses of treatment history suggested that ToM was not affected, however, in CHRs with lifetime histories of both antipsychotic and antidepressant medications. Reduction in age-expected ToM ability may impair the ability of individuals at CHR to meet social developmental challenges in adolescence. Medication effects on social cognition deserve further study. Copyright © 2018. Published by Elsevier B.V.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28286595','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28286595"><span>Same-Sex Behavior and its Relationship with Sexual and Health-Related Practices Among a Population-Based Sample of Women in Puerto Rico: Implications for Cancer Prevention and Control.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Soto-Salgado, Marievelisse; Colón-López, Vivian; Perez, Cynthia; Muñoz-Masso, Cristina; Marrero, Edmir; Suárez, Erick; Ortiz, Ana P</p> <p>2016-01-01</p> <p>This secondary data analysis aimed to estimate the prevalence of same-sex behavior and sexual and health-related practices of a population-based sample (n=560) of women aged 16-64 years in Puerto Rico (PR). Data collection included interviews and biologic samples. Seven percent of the sample had had sex with other women (WSW). Age-adjusted logistic regression models indicated that WSW had higher odds of history of cancer, having ≥ 7 lifetime sexual partners, using sex toys and sharing them, and use of tobacco and illicit drugs. Future research is needed to address the health needs of WSW, including cancer-related risk factors and sexual practices.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26150229','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26150229"><span>Infraocclusion: Dental development and associated dental variations in singletons and twins.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Odeh, Ruba; Townsend, Grant; Mihailidis, Suzanna; Lähdesmäki, Raija; Hughes, Toby; Brook, Alan</p> <p>2015-09-01</p> <p>The aim of this study was to investigate the prevalence of selected dental variations in association with infraocclusion, as well as determining the effects of infraocclusion on dental development and tooth size, in singletons and twins. Two samples were analysed. The first sample comprised 1454 panoramic radiographs of singleton boys and girls aged 8-11 years. The second sample comprised dental models of 202 pairs of monozygotic and dizygotic twins aged 8-11 years. Adobe Photoshop CS5 was used to construct reference lines and measure the extent of infraocclusion (in mm) of primary molars on the panoramic radiographs and on 2D images obtained from the dental models. The panoramic radiographs were examined for the presence of selected dental variations and to assess dental development following the Demirjian and Willems systems. The twins' dental models were measured to assess mesiodistal crown widths. In the singleton sample there was a significant association of canines in an altered position during eruption and the lateral incisor complex (agenesis and/or small tooth size) with infraocclusion (P<0.001), but there was no significant association between infraocclusion and agenesis of premolars. Dental age assessment revealed that dental development was delayed in individuals with infraocclusion compared to controls. The primary mandibular canines were significantly smaller in size in the infraoccluded group (P<0.05). The presence of other dental variations in association with infraocclusion, as well as delayed dental development and reduced tooth size, suggests the presence of a pleiotropic effect. The underlying aetiological factors may be genetic and/or epigenetic. Copyright © 2015 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/1394121','SCIGOV-DOEDE'); return false;" href="https://www.osti.gov/servlets/purl/1394121"><span>Trifluoromethyl Sulfur Pentafluoride (SF5CF3) and Sulfur Hexafluoride (SF6) from Dome Concordia (1965-1999)</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/dataexplorer">DOE Data Explorer</a></p> <p>Sturges, W. T. [School of Environmental Sciences, University of East Anglia, Norwich, United Kingdom; Wallington, T. J. [Ford Motor Company, Dearborn, Michigan; Hurley, M. D. [Ford Motor Company, Dearborn, Michigan; Shine, K. P. [Department of Meteorology, University of Reading, Reading, United Kingdom; Sihra, K. [Department of Meteorology, University of Reading, Reading, United Kingdom; Engel, A. [Institute for Meteorology and Geophysics, Johann Wolfgang Goethe University of Frankfurt, Frankfurt, Germany; Oram, D. E. [School of Environmental Sciences, University of East Anglia, Norwich, United Kingdom; Penkett, S. A. [School of Environmental Sciences, University of East Anglia, Norwich, United Kingdom; Mulvaney, R. [British Antarctic Survey, Natural Environmental Research Council, Cambridge, United Kingdom; Brenninkmeijer, C A. M. [Atmospheric Chemistry Division, Max Planck Institute for Chemistry, Mainz, Germany</p> <p>2000-10-01</p> <p>The sampling and analytical methods are described more fully in Sturges et al. (2000). In summary, air samples were pumped from consolidated deep snow (firn) at Dome Concordia (eastern Antarctica) in December 1998 and January 1999, from the surface to a depth of approximately 100 m. Air samples were analyzed with a gas chromatograph - mass spectrometer, with a detection limit of about 0.001 parts per trillion (ppt). A diffusive transport model was used to calculate the age of samples as a function of depth. Measurements of SF6 were used to determine the mean age of the firn air by comparison with extrapolated measurements from Cape Grim, Tasmania combined with estimates from industrial emissions (Maiss and Brenninkmeijer 1998, adapted by Sturges et al. 2000). Dates for SF5CF3 are different than for SF6 due to the lower diffusivity of SF5CF3: the SF6 ages were multiplied by the ratio of the free-air diffusion coefficient of SF5CF3 to that of SF6 (1.18). Free-air diffusion coefficients were determined by a semi-empirical formula based on molecular volumes (Fuller et al. 1966). Note that mean ages represent a very wide distribution of probable ages spanning many years, with an increasing spread of ages at increasing depth</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li class="active"><span>13</span></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_13 --> <div id="page_14" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li class="active"><span>14</span></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="261"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22301186','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22301186"><span>Towards child versus adult brain mechanical properties.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Chatelin, S; Vappou, J; Roth, S; Raul, J S; Willinger, R</p> <p>2012-02-01</p> <p>The characterization of brain tissue mechanical properties is of crucial importance in the development of realistic numerical models of the human head. While the mechanical behavior of the adult brain has been extensively investigated in several studies, there is a considerable paucity of data concerning the influence of age on mechanical properties of the brain. Therefore, the implementation of child and infant head models often involves restrictive assumptions like properties scaling from adult or animal data. The present study presents a step towards the investigation of the effects of age on viscoelastic properties of human brain tissue from a first set of dynamic oscillatory shear experiments. Tests were also performed on three different locations of brain (corona radiata, thalamus and brainstem) in order to investigate regional differences. Despite the limited number of child brain samples a significant increase in both storage and loss moduli occurring between the age of 5 months and the age of 22 months was found, confirmed by statistical Student's t-tests (p=0.104,0.038 and 0.054 for respectively corona radiata, thalamus and brain stem samples locations respectively). The adult brain appears to be 3-4 times stiffer than the young child one. Moreover, the brainstem was found to be approximately 2-3 times stiffer than both gray and white matter from corona radiata and thalamus. As a tentative conclusion, this study provides the first rheological data on the human brain at different ages and brain regions. This data could be implemented in numerical models of the human head, especially in models concerning pediatric population. Copyright © 2011 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70028128','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70028128"><span>Age model for a continuous, ca 250-ka Quaternary lacustrine record from Bear Lake, Utah-Idaho</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Colman, Steven M.; Kaufman, D.S.; Bright, Jordon; Heil, C.; King, J.W.; Dean, W.E.; Rosenbaum, J.G.; Forester, R.M.; Bischoff, J.L.; Perkins, Marie; McGeehin, J.P.</p> <p>2006-01-01</p> <p>The Quaternary sediments sampled by continuous 120-m-long drill cores from Bear Lake (Utah-Idaho) comprise one of the longest lacustrine sequences recovered from an extant lake. The cores serve as a good case study for the construction of an age model for sequences that extend beyond the range of radiocarbon dating. From a variety of potential age indicators, we selected a combination of radiocarbon ages, one magnetic excursion (correlated to a standard sequence), and a single Uranium-series age to develop an initial data set. The reliability of the excursion and U-series data require consideration of their position with respect to sediments of inferred interglacial character, but not direct correlation with other paleoclimate records. Data omitted from the age model include amino acid age estimates, which have a large amount of scatter, and tephrochronology correlations, which have relatively large uncertainties. Because the initial data set was restricted to the upper half of the BL00-1 core, we inferred additional ages by direct correlation to the independently dated paleoclimate record from Devils Hole. We developed an age model for the entire core using statistical methods that consider both the uncertainties of the original data and that of the curve-fitting process, with a combination of our initial data set and the climate correlations as control points. This age model represents our best estimate of the chronology of deposition in Bear Lake. Because the age model contains assumptions about the correlation of Bear Lake to other climate records, the model cannot be used to address some paleoclimate questions, such as phase relationships with other areas.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25879872','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25879872"><span>An application in identifying high-risk populations in alternative tobacco product use utilizing logistic regression and CART: a heuristic comparison.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lei, Yang; Nollen, Nikki; Ahluwahlia, Jasjit S; Yu, Qing; Mayo, Matthew S</p> <p>2015-04-09</p> <p>Other forms of tobacco use are increasing in prevalence, yet most tobacco control efforts are aimed at cigarettes. In light of this, it is important to identify individuals who are using both cigarettes and alternative tobacco products (ATPs). Most previous studies have used regression models. We conducted a traditional logistic regression model and a classification and regression tree (CART) model to illustrate and discuss the added advantages of using CART in the setting of identifying high-risk subgroups of ATP users among cigarettes smokers. The data were collected from an online cross-sectional survey administered by Survey Sampling International between July 5, 2012 and August 15, 2012. Eligible participants self-identified as current smokers, African American, White, or Latino (of any race), were English-speaking, and were at least 25 years old. The study sample included 2,376 participants and was divided into independent training and validation samples for a hold out validation. Logistic regression and CART models were used to examine the important predictors of cigarettes + ATP users. The logistic regression model identified nine important factors: gender, age, race, nicotine dependence, buying cigarettes or borrowing, whether the price of cigarettes influences the brand purchased, whether the participants set limits on cigarettes per day, alcohol use scores, and discrimination frequencies. The C-index of the logistic regression model was 0.74, indicating good discriminatory capability. The model performed well in the validation cohort also with good discrimination (c-index = 0.73) and excellent calibration (R-square = 0.96 in the calibration regression). The parsimonious CART model identified gender, age, alcohol use score, race, and discrimination frequencies to be the most important factors. It also revealed interesting partial interactions. The c-index is 0.70 for the training sample and 0.69 for the validation sample. The misclassification rate was 0.342 for the training sample and 0.346 for the validation sample. The CART model was easier to interpret and discovered target populations that possess clinical significance. This study suggests that the non-parametric CART model is parsimonious, potentially easier to interpret, and provides additional information in identifying the subgroups at high risk of ATP use among cigarette smokers.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5385728','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5385728"><span>Pancreatic protective and hypoglycemic effects of Vitex agnus-castus L. fruit hydroalcoholic extract in D-galactose-induced aging mouse model</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Ahangarpour, Akram; Oroojan, Ali Akbar; Khorsandi, Layasadat; Najimi, Seyedeh Asma</p> <p>2017-01-01</p> <p>D-galactose induces pancreatic disorder along with aging mouse model. Vitex agnus-castus (VAC) has potential pancreatic protective effect. Hence, this study was designed to evaluate the hypoglycemic and pancreas protective effects of VAC hydroalcoholic extract in D-galactose-induced aging female mice. In the present experimental study, 72 adult female Naval Medical Research Institute (NMRI) mice (weighing 30–35 g) were divided into 6 groups of control, VAC hydroalcoholic extract, D-galactose, D-galactose + VAC hydroalcoholic extract, aged, aged + VAC hydroalcoholic extract. The aged model was prepared by subcutaneous injection of D-galactose for 45 days and, VAC hydroalcoholic extract was gavaged twice a day in the last 7 days. 24 h after the last drug and extract administrations, serum samples and pancreatic tissues were removed to evaluate experimental and histological determinations. Serum glucose level decreased in VAC, D-galactose and, aged-treated groups compared to the control (P < 0.05). Insulin level increased in VAC and decreased in D-galactose and aged VAC-treated mice compared to the control (P < 0.05). Homeostasis model assessment-estimated insulin resistance (HOMA-IR) increased in D-galactose, aging, and VAC hydroalcoholic extract groups (P < 0.05) and, administration of VAC hydroalcoholic extract improved HOMA-IR in D-galactose and aging treated animals. Despite the size of pancreatic islets decreased in aged and D-galactose groups, VAC administration recovered it. Present data showed that VAC hydroalcoholic extract has hypoglycemic and pancreatic protective effects in natural aged and aging model mice. PMID:28515766</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28515766','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28515766"><span>Pancreatic protective and hypoglycemic effects of Vitex agnus-castus L. fruit hydroalcoholic extract in D-galactose-induced aging mouse model.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ahangarpour, Akram; Oroojan, Ali Akbar; Khorsandi, Layasadat; Najimi, Seyedeh Asma</p> <p>2017-04-01</p> <p>D-galactose induces pancreatic disorder along with aging mouse model. Vitex agnus-castus (VAC) has potential pancreatic protective effect. Hence, this study was designed to evaluate the hypoglycemic and pancreas protective effects of VAC hydroalcoholic extract in D-galactose-induced aging female mice. In the present experimental study, 72 adult female Naval Medical Research Institute (NMRI) mice (weighing 30-35 g) were divided into 6 groups of control, VAC hydroalcoholic extract, D-galactose, D-galactose + VAC hydroalcoholic extract, aged, aged + VAC hydroalcoholic extract. The aged model was prepared by subcutaneous injection of D-galactose for 45 days and, VAC hydroalcoholic extract was gavaged twice a day in the last 7 days. 24 h after the last drug and extract administrations, serum samples and pancreatic tissues were removed to evaluate experimental and histological determinations. Serum glucose level decreased in VAC, D-galactose and, aged-treated groups compared to the control ( P < 0.05). Insulin level increased in VAC and decreased in D-galactose and aged VAC-treated mice compared to the control ( P < 0.05). Homeostasis model assessment-estimated insulin resistance (HOMA-IR) increased in D-galactose, aging, and VAC hydroalcoholic extract groups ( P < 0.05) and, administration of VAC hydroalcoholic extract improved HOMA-IR in D-galactose and aging treated animals. Despite the size of pancreatic islets decreased in aged and D-galactose groups, VAC administration recovered it. Present data showed that VAC hydroalcoholic extract has hypoglycemic and pancreatic protective effects in natural aged and aging model mice.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24347839','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24347839"><span>Sample size estimation for alternating logistic regressions analysis of multilevel randomized community trials of under-age drinking.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Reboussin, Beth A; Preisser, John S; Song, Eun-Young; Wolfson, Mark</p> <p>2012-07-01</p> <p>Under-age drinking is an enormous public health issue in the USA. Evidence that community level structures may impact on under-age drinking has led to a proliferation of efforts to change the environment surrounding the use of alcohol. Although the focus of these efforts is to reduce drinking by individual youths, environmental interventions are typically implemented at the community level with entire communities randomized to the same intervention condition. A distinct feature of these trials is the tendency of the behaviours of individuals residing in the same community to be more alike than that of others residing in different communities, which is herein called 'clustering'. Statistical analyses and sample size calculations must account for this clustering to avoid type I errors and to ensure an appropriately powered trial. Clustering itself may also be of scientific interest. We consider the alternating logistic regressions procedure within the population-averaged modelling framework to estimate the effect of a law enforcement intervention on the prevalence of under-age drinking behaviours while modelling the clustering at multiple levels, e.g. within communities and within neighbourhoods nested within communities, by using pairwise odds ratios. We then derive sample size formulae for estimating intervention effects when planning a post-test-only or repeated cross-sectional community-randomized trial using the alternating logistic regressions procedure.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29085391','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29085391"><span>A binary logistic regression model with complex sampling design of unmet need for family planning among all women aged (15-49) in Ethiopia.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Workie, Demeke Lakew; Zike, Dereje Tesfaye; Fenta, Haile Mekonnen; Mekonnen, Mulusew Admasu</p> <p>2017-09-01</p> <p>Unintended pregnancy related to unmet need is a worldwide problem that affects societies. The main objective of this study was to identify the prevalence and determinants of unmet need for family planning among women aged (15-49) in Ethiopia. The Performance Monitoring and Accountability2020/Ethiopia was conducted in April 2016 at round-4 from 7494 women with two-stage-stratified sampling. Bi-variable and multi-variable binary logistic regression model with complex sampling design was fitted. The prevalence of unmet-need for family planning was 16.2% in Ethiopia. Women between the age range of 15-24 years were 2.266 times more likely to have unmet need family planning compared to above 35 years. Women who were currently married were about 8 times more likely to have unmet need family planning compared to never married women. Women who had no under-five child were 0.125 times less likely to have unmet need family planning compared to those who had more than two-under-5. The key determinants of unmet need family planning in Ethiopia were residence, age, marital-status, education, household members, birth-events and number of under-5 children. Thus the Government of Ethiopia would take immediate steps to address the causes of high unmet need for family planning among women.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4476712','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4476712"><span>Improving the Rank Precision of Population Health Measures for Small Areas with Longitudinal and Joint Outcome Models</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Athens, Jessica K.; Remington, Patrick L.; Gangnon, Ronald E.</p> <p>2015-01-01</p> <p>Objectives The University of Wisconsin Population Health Institute has published the County Health Rankings since 2010. These rankings use population-based data to highlight health outcomes and the multiple determinants of these outcomes and to encourage in-depth health assessment for all United States counties. A significant methodological limitation, however, is the uncertainty of rank estimates, particularly for small counties. To address this challenge, we explore the use of longitudinal and pooled outcome data in hierarchical Bayesian models to generate county ranks with greater precision. Methods In our models we used pooled outcome data for three measure groups: (1) Poor physical and poor mental health days; (2) percent of births with low birth weight and fair or poor health prevalence; and (3) age-specific mortality rates for nine age groups. We used the fixed and random effects components of these models to generate posterior samples of rates for each measure. We also used time-series data in longitudinal random effects models for age-specific mortality. Based on the posterior samples from these models, we estimate ranks and rank quartiles for each measure, as well as the probability of a county ranking in its assigned quartile. Rank quartile probabilities for univariate, joint outcome, and/or longitudinal models were compared to assess improvements in rank precision. Results The joint outcome model for poor physical and poor mental health days resulted in improved rank precision, as did the longitudinal model for age-specific mortality rates. Rank precision for low birth weight births and fair/poor health prevalence based on the univariate and joint outcome models were equivalent. Conclusion Incorporating longitudinal or pooled outcome data may improve rank certainty, depending on characteristics of the measures selected. For measures with different determinants, joint modeling neither improved nor degraded rank precision. This approach suggests a simple way to use existing information to improve the precision of small-area measures of population health. PMID:26098858</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27125763','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27125763"><span>Environmental stress cracking performance of polyether and PDMS-based polyurethanes in an in vitro oxidation model.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Gallagher, Genevieve; Padsalgikar, Ajay; Tkatchouk, Ekaterina; Jenney, Chris; Iacob, Ciprian; Runt, James</p> <p>2017-08-01</p> <p>Environmental stress cracking (ESC) was replicated in vitro on Optim™ (OPT) insulation, a polydimethylsiloxane-based polyurethane utilized clinically in cardiac leads, using a Zhao-type oxidation model. OPT performance was compared to that of two industry standard polyether urethanes: Pellethane ® 80A (P80A), and Pellethane ® 55D (P55D). Clinically relevant specimen configurations and strain states were utilized: low-voltage cardiac lead segments were held in a U-shape by placing them inside of vials. To study whether aging conditions impacted ESC formation, half of the samples were subjected to a pretreatment in human plasma for 7 days at 37°C; all samples were then aged in oxidative solutions containing 0.9% NaCl, 20% H 2 O 2 , and either 0 or 0.1M CoCl 2 , with or without glass wool for 72 days at 37°C. Visual and SEM inspection revealed significant surface cracking consistent with ESC on all P80A and P55D samples. Sixteen of twenty P80A and 10/20 P55D samples also exhibited breaches. Seven of 20 OPT samples exhibited shallow surface cracking consistent with ESC. ATR-FTIR confirmed surface changes consistent with oxidation for all materials. The number average molecular weight decreased an average of 31% for OPT, 86% for P80A, and 56% for P55D samples. OPT outperformed P80A and P55D in this Zhao-type in vitro ESC model. An aging solution of 0.9% NaCl, 20% H 2 O 2 , and 0.1M CoCl 2 , with glass wool provided the best combination of ESC replication and ease of use. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 1544-1558, 2017. © 2016 Wiley Periodicals, Inc.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/1093269','DOE-PATENT-XML'); return false;" href="https://www.osti.gov/servlets/purl/1093269"><span>Systems, methods and computer-readable media for modeling cell performance fade of rechargeable electrochemical devices</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/doepatents">DOEpatents</a></p> <p>Gering, Kevin L</p> <p>2013-08-27</p> <p>A system includes an electrochemical cell, monitoring hardware, and a computing system. The monitoring hardware periodically samples performance characteristics of the electrochemical cell. The computing system determines cell information from the performance characteristics of the electrochemical cell. The computing system also develops a mechanistic level model of the electrochemical cell to determine performance fade characteristics of the electrochemical cell and analyzing the mechanistic level model to estimate performance fade characteristics over aging of a similar electrochemical cell. The mechanistic level model uses first constant-current pulses applied to the electrochemical cell at a first aging period and at three or more current values bracketing a first exchange current density. The mechanistic level model also is based on second constant-current pulses applied to the electrochemical cell at a second aging period and at three or more current values bracketing the second exchange current density.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22895578','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22895578"><span>C-reactive protein and familial risk for dementia: a phenotype for successful cognitive aging.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Silverman, Jeremy M; Schmeidler, James; Beeri, Michal S; Rosendorff, Clive; Sano, Mary; Grossman, Hillel T; Carrión-Baralt, José R; Bespalova, Irina N; West, Rebecca; Haroutunian, Vahram</p> <p>2012-09-11</p> <p>Identifying phenotypes for successful cognitive aging, intact cognition into late-old age (>age 75), can help identify genes and neurobiological systems that may lead to interventions against and prevention of late-life cognitive impairment. The association of C-reactive protein (CRP) with cognitive impairment and dementia, observed primarily in young-elderly samples, appears diminished or reversed in late-old age (75+ years). A family history study determined if high CRP levels in late-old aged cognitively intact probands are associated with a reduced risk of dementia in their first-degree family members, suggesting a familial successful cognitive aging phenotype. The primary sample was 1,329 parents and siblings of 277 cognitively intact male veteran probands at least 75 years old. The replication sample was 202 relatives of 51 cognitively intact community-ascertained probands at least 85 years old. Relatives were assessed for dementia by proband informant interview. Their hazard ratio (HR) for dementia as a function of the proband's log-transformed CRP was calculated using the proportional hazards model. Covarying for key demographics, higher CRP in probands was strongly associated with lower risk of dementia in relatives (HR = 0.55 [95% confidence interval (CI) 0.41, 0.74], p < 0.02). The replication sample relationship was in the same direction, stronger in magnitude, and also significant (HR = 0.15 [95% CI 0.06, 0.37], p < 0.0001). Relatives of successful cognitive aging individuals with high levels of CRP are relatively likely to remain free of dementia. High CRP in successful cognitive aging individuals may constitute a phenotype for familial-and thus possibly genetic-successful cognitive aging.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28439695','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28439695"><span>Usefulness of telomere length in DNA from human teeth for age estimation.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Márquez-Ruiz, Ana Belén; González-Herrera, Lucas; Valenzuela, Aurora</p> <p>2018-03-01</p> <p>Age estimation is widely used to identify individuals in forensic medicine. However, the accuracy of the most commonly used procedures is markedly reduced in adulthood, and these methods cannot be applied in practice when morphological information is limited. Molecular methods for age estimation have been extensively developed in the last few years. The fact that telomeres shorten at each round of cell division has led to the hypothesis that telomere length can be used as a tool to predict age. The present study thus aimed to assess the correlation between telomere length measured in dental DNA and age, and the effect of sex and tooth type on telomere length; a further aim was to propose a statistical regression model to estimate the biological age based on telomere length. DNA was extracted from 91 tooth samples belonging to 77 individuals of both sexes and 15 to 85 years old and was used to determine telomere length by quantitative real-time PCR. Our results suggested that telomere length was not affected by sex and was greater in molar teeth. We found a significant correlation between age and telomere length measured in DNA from teeth. However, the equation proposed to predict age was not accurate enough for forensic age estimation on its own. Age estimation based on telomere length in DNA from tooth samples may be useful as a complementary method which provides an approximate estimate of age, especially when human skeletal remains are the only forensic sample available.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26728911','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26728911"><span>Predictive Factors of Regular Physical Activity among Middle-Aged Women in the West of Iran, Hamadan: Application of PRECEDE Model.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Emdadi, Shohreh; Hazavehie, Seyed Mohammad Mehdi; Soltanian, Alireza; Bashirian, Saeed; Heidari Moghadam, Rashid</p> <p>2015-01-01</p> <p>Regular physical activity is important for midlife women. Models and theories help better understanding this behavior among middle-aged women and better planning for change behavior in target group. This study aimed to investigate predictive factors of regular physical activity among middle-aged women based on PRECEDE model as a theoretical framework. This descriptive-analytical study was performed on 866 middle-aged women of Hamadan City western Iran, recruited with a proportional stratified sampling method in 2015. The participants completed a self-administered questionnaire including questions on demographic characteristics and PRECEDE model constructs and IPAQ questionnaire. Data were then analyzed by SPSS-16 and AMOS-16 using the Pearson correlation test and the pathway analysis method. Overall, 57% of middle-aged women were inactive (light level) or not sufficiently active. With SEM (Structural Equation Modeling) analysis, knowledge b=0.84, P<0.001, attitude b=0.799, P<0.001, self-efficacy b=0.633, P<0.001 as predisposing factor and social support as reinforcing factor b=0.2, P<0.001 were the most important predictors for physical activity among middle-aged women in Hamadan. The framework of the PRECEDE model is useful in understanding regular physical activity among middle-aged women. Furthermore, results showed the importance of predisposing and reinforcing factors when planning educational interventions.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017GPC...152...38S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017GPC...152...38S"><span>Late Burdigalian sea retreat from the North Alpine Foreland Basin: new magnetostratigraphic age constraints</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sant, K.; Kirscher, U.; Reichenbacher, B.; Pippèrr, M.; Jung, D.; Doppler, G.; Krijgsman, W.</p> <p>2017-05-01</p> <p>Accurate reconstruction of the final sea retreat from the North Alpine Foreland Basin (NAFB) during the Burdigalian (Early Miocene) is hampered by a lack of reliable age constraints. In this high resolution magnetostratigraphic study we try to solve a significant age bias for the onset of the Upper Freshwater Molasse (OSM) deposition in the neighboring S-German and Swiss Molasse Basins. We measured > 550 samples from eleven drill cores covering the transition from marine to brackish to freshwater environments in the S-German Molasse Basin. Based on combined bio-, litho- and magnetostratigraphic constraints, the composite magnetostratigraphic pattern of these cores provides two reasonable age correlation options (model 1 and 2). In model 1, the base of the brackish succession lies within Chron C5Cr ( 16.7-17.2 Ma), and the onset of OSM deposition has an age of 16.5 Ma. Correlation model 2 suggests the transition to brackish conditions to be within C5Dr.1r ( 17.7-17.5 Ma), and yields an age around 16.7 Ma for the shift to the OSM. Most importantly, both models confirm a much younger age for the OSM base in the study area than previously suggested. Our results demonstrate a possible coincidence of the last transgressive phase (Kirchberg Fm) with the Miocene Climatic Optimum (model 1), or with the onset of this global warming event (model 2). In contrast, the final retreat of the sea from the study area is apparently not controlled by climate change. Supplementary material B. Profiles of the eleven studied drill cores including lithologies, all magnetostratigraphic data (inclinations), interpreted polarity pattern (this study and Reichenbacher et al., 2013) and magnetic susceptibility (this study). Legend for graphs on page 1. Samples without a stable direction above 200 °C or 20 mT are depicted as +-signs and plotted at 0° inclination. The interpreted normal (black), reversed (white) and uncertain (grey) polarity zones in the polarity columns are based on at least two medium to high quality levels. Divergent or isolated polarity results based on only one level are marked with half bars.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70179869','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70179869"><span>Using groundwater age distributions to understand changes in methyl tert-butyl ether (MtBE) concentrations in ambient groundwater, northeastern United States</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Lindsey, Bruce; Ayotte, Joseph; Jurgens, Bryant; DeSimone, Leslie A.</p> <p>2017-01-01</p> <p>Temporal changes in methyl tert-butyl ether (MtBE) concentrations in groundwater were evaluated in the northeastern United States, an area of the nation with widespread low-level detections of MtBE based on a national survey of wells selected to represent ambient conditions. MtBE use in the U.S. peaked in 1999 and was largely discontinued by 2007. Six well networks, each representing specific areas and well types (monitoring or supply wells), were each sampled at 10 year intervals between 1996 and 2012. Concentrations were decreasing or unchanged in most wells as of 2012, with the exception of a small number of wells where concentrations continue to increase. Statistically significant increasing concentrations were found in one network sampled for the second time shortly after the peak of MtBE use, and decreasing concentrations were found in two networks sampled for the second time about 10 years after the peak of MtBE use. Simulated concentrations from convolutions of estimates for concentrations of MtBE in recharge water with age distributions from environmental tracer data correctly predicted the direction of MtBE concentration changes in about 65 percent of individual wells. The best matches between simulated and observed concentrations were found when simulating recharge concentrations that followed the pattern of national MtBE use. Some observations were matched better when recharge was modeled as a plume moving past the well from a spill at one point in time. Modeling and sample results showed that wells with young median ages and narrow age distributions responded more quickly to changes in the contaminant source than wells with older median ages and broad age distributions. Well depth and aquifer type affect these responses. Regardless of the timing of decontamination, all of these aquifers show high susceptibility for contamination by a highly soluble, persistent constituent.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70030196','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70030196"><span>Groundwater noble gas, age, and temperature signatures in an Alpine watershed: Valuable tools in conceptual model development</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Manning, Andrew H.; Caine, Jonathan S.</p> <p>2007-01-01</p> <p>Bedrock groundwater in alpine watersheds is poorly understood, mainly because of a scarcity of wells in alpine settings. Groundwater noble gas, age, and temperature data were collected from springs and wells with depths of 3–342 m in Handcart Gulch, an alpine watershed in Colorado. Temperature profiles indicate active groundwater circulation to a maximum depth (aquifer thickness) of about 200 m, or about 150 m below the water table. Dissolved noble gas data show unusually high excess air concentrations (>0.02 cm3 STP/g, ΔNe > 170%) in the bedrock, consistent with unusually large seasonal water table fluctuations (up to 50 m) observed in the upper part of the watershed. Apparent 3H/3He ages are positively correlated with sample depth and excess air concentrations. Integrated samples were collected from artesian bedrock wells near the trunk stream and are assumed to approximate flow‐weighted samples reflecting bedrock aquifer mean residence times. Exponential mean ages for these integrated samples are remarkably consistent along the stream, four of five being from 8 to 11 years. The tracer data in combination with other hydrologic and geologic data support a relatively simple conceptual model of groundwater flow in the watershed in which (1) permeability is primarily a function of depth; (2) water table fluctuations increase with distance from the stream; and (3) recharge, aquifer thickness, and porosity are relatively uniform throughout the watershed in spite of the geological complexity of the Proterozoic crystalline rocks that underlie it.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21524517','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21524517"><span>Short communication: Assessing antihypertensive activity in native and model Queso Fresco cheeses.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Paul, M; Van Hekken, D L</p> <p>2011-05-01</p> <p>Hispanic-style cheeses are one of the fastest growing varieties in the United States, making up approximately 2% of the total cheese production in this country. Queso Fresco is one of most popular Hispanic-style cheeses. Protein extracts from several varieties of Mexican Queso Fresco and model Queso Fresco were analyzed for potential antihypertensive activity. Many Quesos Frescos obtained from Mexico are made from raw milk and therefore the native microflora is included in the cheese-making process. Model Queso Fresco samples were made from pasteurized milk and did not utilize starter cultures. Water-soluble protein extracts from 6 Mexican Quesos Frescos and 12 model cheeses were obtained and assayed for their ability to inhibit angiotensin-converting enzyme, implying potential as foods that can help to lower blood pressure. All model cheeses displayed antihypertensive activity, but mainly after 8 wk of aging when they were no longer consumable, whereas the Mexican samples did display some angiotensin-converting enzyme inhibitory action after minimal aging. Copyright © 2011 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23280257','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23280257"><span>Random glucose is useful for individual prediction of type 2 diabetes: results of the Study of Health in Pomerania (SHIP).</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kowall, Bernd; Rathmann, Wolfgang; Giani, Guido; Schipf, Sabine; Baumeister, Sebastian; Wallaschofski, Henri; Nauck, Matthias; Völzke, Henry</p> <p>2013-04-01</p> <p>Random glucose is widely used in routine clinical practice. We investigated whether this non-standardized glycemic measure is useful for individual diabetes prediction. The Study of Health in Pomerania (SHIP), a population-based cohort study in north-east Germany, included 3107 diabetes-free persons aged 31-81 years at baseline in 1997-2001. 2475 persons participated at 5-year follow-up and gave self-reports of incident diabetes. For the total sample and for subjects aged ≥50 years, statistical properties of prediction models with and without random glucose were compared. A basic model (including age, sex, diabetes of parents, hypertension and waist circumference) and a comprehensive model (additionally including various lifestyle variables and blood parameters, but not HbA1c) performed statistically significantly better after adding random glucose (e.g., the area under the receiver-operating curve (AROC) increased from 0.824 to 0.856 after adding random glucose to the comprehensive model in the total sample). Likewise, adding random glucose to prediction models which included HbA1c led to significant improvements of predictive ability (e.g., for subjects ≥50 years, AROC increased from 0.824 to 0.849 after adding random glucose to the comprehensive model+HbA1c). Random glucose is useful for individual diabetes prediction, and improves prediction models including HbA1c. Copyright © 2012 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29172870','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29172870"><span>Identifying Risk Factors for Drug Use in an Iranian Treatment Sample: A Prediction Approach Using Decision Trees.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Amirabadizadeh, Alireza; Nezami, Hossein; Vaughn, Michael G; Nakhaee, Samaneh; Mehrpour, Omid</p> <p>2018-05-12</p> <p>Substance abuse exacts considerable social and health care burdens throughout the world. The aim of this study was to create a prediction model to better identify risk factors for drug use. A prospective cross-sectional study was conducted in South Khorasan Province, Iran. Of the total of 678 eligible subjects, 70% (n: 474) were randomly selected to provide a training set for constructing decision tree and multiple logistic regression (MLR) models. The remaining 30% (n: 204) were employed in a holdout sample to test the performance of the decision tree and MLR models. Predictive performance of different models was analyzed by the receiver operating characteristic (ROC) curve using the testing set. Independent variables were selected from demographic characteristics and history of drug use. For the decision tree model, the sensitivity and specificity for identifying people at risk for drug abuse were 66% and 75%, respectively, while the MLR model was somewhat less effective at 60% and 73%. Key independent variables in the analyses included first substance experience, age at first drug use, age, place of residence, history of cigarette use, and occupational and marital status. While study findings are exploratory and lack generalizability they do suggest that the decision tree model holds promise as an effective classification approach for identifying risk factors for drug use. Convergent with prior research in Western contexts is that age of drug use initiation was a critical factor predicting a substance use disorder.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=adolescent+AND+sexual+AND+health&pg=6&id=EJ988684','ERIC'); return false;" href="https://eric.ed.gov/?q=adolescent+AND+sexual+AND+health&pg=6&id=EJ988684"><span>Psychosocial Processes and Sexual Initiation among Ghanaian Youth</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>McQuestion, Michael; Ahiadeke, Clement; Posner, Jessica; Williams, Timothy</p> <p>2012-01-01</p> <p>This study models primary abstinence and age at first sex in a cross-sectional sample of Ghanaian youth aged 17 to 22 years. The aim is to examine how reproductive knowledge and social cognitive factors jointly affect the choice to initiate sex. Among males, the authors find that reproductive knowledge is negatively associated with abstinence. Its…</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li class="active"><span>14</span></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_14 --> <div id="page_15" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li class="active"><span>15</span></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="281"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=Amotivation&pg=7&id=EJ861182','ERIC'); return false;" href="https://eric.ed.gov/?q=Amotivation&pg=7&id=EJ861182"><span>Developmental Trajectories of Motivation in Physical Education: Course, Demographic Differences, and Antecedents</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Ntoumanis, Nikos; Barkoukis, Vassilis; Thogersen-Ntoumani, Cecilie</p> <p>2009-01-01</p> <p>This study investigated changes in student motivation to participate in physical education and some determinants of these changes over a period of 3 years. Measures were taken twice a year, from age 13 until age 15, from a sample of Greek junior high school students. Multilevel modeling analyses showed significant decreases in task-involving…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=economic+AND+intelligence&pg=2&id=EJ867520','ERIC'); return false;" href="https://eric.ed.gov/?q=economic+AND+intelligence&pg=2&id=EJ867520"><span>Social Status, Cognitive Ability, and Educational Attainment as Predictors of Liberal Social Attitudes and Political Trust</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Schoon, Ingrid; Cheng, Helen; Gale, Catharine R.; Batty, G. David; Deary, Ian J.</p> <p>2010-01-01</p> <p>We examined the prospective associations between family socio-economic background, childhood intelligence ("g") at age 11, educational and occupational attainment, and social attitudes at age 33 in a large (N = 8804), representative sample of the British population born in 1958. Structural equation Modeling identified a latent trait of…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=5S&pg=6&id=EJ1079376','ERIC'); return false;" href="https://eric.ed.gov/?q=5S&pg=6&id=EJ1079376"><span>Visuomotor Integration and Inhibitory Control Compensate for Each Other in School Readiness</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Cameron, Claire E.; Brock, Laura L.; Hatfield, Bridget E.; Cottone, Elizabeth A.; Rubinstein, Elise; LoCasale-Crouch, Jennifer; Grissmer, David W.</p> <p>2015-01-01</p> <p>Visuomotor integration (VMI), or the ability to copy designs, and 2 measures of executive function were examined in a predominantly low-income, typically developing sample of children (n = 467, mean age 4.2 years) from 5 U.S. states. In regression models controlling for age and demographic variables, we tested the interaction between visuomotor…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=divorce&pg=3&id=EJ879377','ERIC'); return false;" href="https://eric.ed.gov/?q=divorce&pg=3&id=EJ879377"><span>The Interactive Effects of Marital Conflict and Divorce on Parent-Adult Children's Relationships</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Yu, Tianyi; Pettit, Gregory S.; Lansford, Jennifer E.; Dodge, Kenneth A.; Bates, John E.</p> <p>2010-01-01</p> <p>This study examines main effect and interactive models of the relations between marital conflict, divorce, and parent-adult child relationships and gender differences in these relations. Data were drawn from a longitudinal study of a community sample (N = 585). Parental marital conflict and divorce were measured from age 5 through age 17 years.…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4102493','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4102493"><span>The Relationship Between Social Support and Subjective Well-Being Across Age</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Salthouse, Timothy A.; Oishi, Shigehiro; Jeswani, Sheena</p> <p>2014-01-01</p> <p>The relationships among types of social support and different facets of subjective well-being (i.e., life satisfaction, positive affect, and negative affect) were examined in a sample of 1,111 individuals between the ages of 18 and 95. Using structural equation modeling we found that life satisfaction was predicted by enacted and perceived support, positive affect was predicted by family embeddedness and provided support, and negative affect was predicted by perceived support. When personality variables were included in a subsequent model, the influence of the social support variables were generally reduced. Invariance analyses conducted across age groups indicated that there were no substantial differences in predictors of the different types of subjective well-being across age. PMID:25045200</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1065580','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1065580"><span>Toward a model for improved targeting of aged at risk of institutionalization.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Weissert, W G; Cready, C M</p> <p>1989-01-01</p> <p>A national sample of institutionalized and noninstitutionalized aged was created by merging the 1977 National Nursing Home Survey and its counterpart, the National Health Interview Survey for the same year. A weighted logistic regression analysis was conducted to identify factors that might be useful in calculating home- and community-based long-term care clients' risk of institutionalization. A model containing patient characteristics, nursing home bed supply, and a climate variable correctly classified 98.2 percent of cases residing in nursing homes or the community. Physical dependency, mental disorder and degenerative disease, lack of spouse, being white, poverty, old age, unoccupied nursing home beds, and climate all appear to be determinants of institutional residency among the aged. PMID:2807934</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28679152','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28679152"><span>Physical and chemical characterization of representative samples of recycled rubber from end-of-life tires.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Re Depaolini, Andrea; Bianchi, Giancarlo; Fornai, Daniele; Cardelli, Angela; Badalassi, Marco; Cardelli, Camillo; Davoli, Enrico</p> <p>2017-10-01</p> <p>A large number of end-of-life tires (ELTs) were sampled and classified by type, age and origin to obtain recycled rubber samples representative of the materials placed on the Italian market. The selected recycled tire rubber samples were physically and chemically characterized and a chemometric approach was used to determine correlations. The polycyclic aromatic hydrocarbons (PAHs) content was correlated to the aromaticity index and a model was built to establish the H-Bay aromaticity index (H-Bay) from the PAH concentrations. ELT of different origin and age produced in non-European countries generally had higher PAH content and a higher H-Bay index. H-Bay values of all the samples were lower than the REACH limits and old tires had higher aromatic content than recent ones, possibly due to the replacement of aromatic oils in tire production. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016EGUGA..1813350B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016EGUGA..1813350B"><span>Towards quantifying long-term erosion rates in the Campine Basin, NE Belgium</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Beerten, Koen; Vanacker, Veerle</p> <p>2016-04-01</p> <p>The Campine Basin, NE Belgium, is situated between the uplifting Ardennes Massif and rapidly subsiding Roer Valley Graben. It contains a thick series of marine, estuarine and continental Neogene and Quaternary sediments, locally more than 300 m. As a result of relief inversion during the Quaternary, the Campine Plateau is nowadays a distinct morphological feature in this basin. Its surface elevation dips from 100 m in the south to 30 m in the north over a distance of about 60 km, which is the result of differential uplift. The Campine Plateau is covered by Early and Middle Pleistocene erosion-resistant fluvial sediments from the Rhine and Meuse and can thus be regarded as a fluvial terrace. The age of deposition and time of abandonment of the terrace have not yet been resolved by direct numerical dating. In this study, we apply the cosmogenic radionuclide (CRN) profiling technique that, in ideal circumstances, allows one to constrain the exposure age, burial age and amount of post-depositional erosion of the landform. Samples were taken from a 3.5 m deep cross-section in coarse river sands that were deposited by the river Rhine, and now situated at an altitude of about 50 m (a.s.l.). Nine of them were prepared for CRN measurements according to state-of-the-art techniques. The in-situ 10Be concentration of the samples was determined using accelerator mass spectrometry (ETH, Zurich). The in-situ 10Be concentrations are 1.5x10e5 atoms/g for the uppermost sample (at 0.3 m depth) and 0.9x10e5 at/g for the lowermost sample (at 3.1 m depth), yielding an estimated 0.6x10e5 at/g of radionuclide accumulation following sediment deposition. Using forward modelling, we solved for the exposure duration and erosion rate that best fit the measured in-situ 10Be depth profile data, nuclide inheritance and their associated analytical uncertainties. Model optimisation is here based on the sum of chi-squared between the measured and modelled 10Be concentrations. When taking previous geological age constraints of the sediments (between 0.6 and 1 Ma) into account, the model optimum occurs with a terrace erosion rate of 10 to 25 m/Ma. The uncertainty on the model fit calls for a dense sampling scheme to capture the full spectrum of internal variability in CRN concentrations, likely related to the highly polycyclic nature of the fluvial sedimentary environment. Furthermore, independent age control from OSL, ESR and/or paired Al-Be CRN dating would help to refine the erosional and depositional history of this landform.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3751413','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3751413"><span>Transcriptional profiling reveals progeroid Ercc1-/Δ mice as a model system for glomerular aging</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2013-01-01</p> <p>Background Aging-related kidney diseases are a major health concern. Currently, models to study renal aging are lacking. Due to a reduced life-span progeroid models hold the promise to facilitate aging studies and allow examination of tissue-specific changes. Defects in genome maintenance in the Ercc1-/Δ progeroid mouse model result in premature aging and typical age-related pathologies. Here, we compared the glomerular transcriptome of young and aged Ercc1-deficient mice to young and aged WT mice in order to establish a novel model for research of aging-related kidney disease. Results In a principal component analysis, age and genotype emerged as first and second principal components. Hierarchical clustering of all 521 genes differentially regulated between young and old WT and young and old Ercc1-/Δ mice showed cluster formation between young WT and Ercc1-/Δ as well as old WT and Ercc1-/Δ samples. An unexpectedly high number of 77 genes were differentially regulated in both WT and Ercc1-/Δ mice (p < 0.0001). GO term enrichment analysis revealed these genes to be involved in immune and inflammatory response, cell death, and chemotaxis. In a network analysis, these genes were part of insulin signaling, chemokine and cytokine signaling and extracellular matrix pathways. Conclusion Beyond insulin signaling, we find chemokine and cytokine signaling as well as modifiers of extracellular matrix composition to be subject to major changes in the aging glomerulus. At the level of the transcriptome, the pattern of gene activities is similar in the progeroid Ercc1-/Δ mouse model constituting a valuable tool for future studies of aging-associated glomerular pathologies. PMID:23947592</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23947592','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23947592"><span>Transcriptional profiling reveals progeroid Ercc1(-/Δ) mice as a model system for glomerular aging.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Schermer, Bernhard; Bartels, Valerie; Frommolt, Peter; Habermann, Bianca; Braun, Fabian; Schultze, Joachim L; Roodbergen, Marianne; Hoeijmakers, Jan Hj; Schumacher, Björn; Nürnberg, Peter; Dollé, Martijn Et; Benzing, Thomas; Müller, Roman-Ulrich; Kurschat, Christine E</p> <p>2013-08-16</p> <p>Aging-related kidney diseases are a major health concern. Currently, models to study renal aging are lacking. Due to a reduced life-span progeroid models hold the promise to facilitate aging studies and allow examination of tissue-specific changes. Defects in genome maintenance in the Ercc1(-/Δ) progeroid mouse model result in premature aging and typical age-related pathologies. Here, we compared the glomerular transcriptome of young and aged Ercc1-deficient mice to young and aged WT mice in order to establish a novel model for research of aging-related kidney disease. In a principal component analysis, age and genotype emerged as first and second principal components. Hierarchical clustering of all 521 genes differentially regulated between young and old WT and young and old Ercc1(-/Δ) mice showed cluster formation between young WT and Ercc1(-/Δ) as well as old WT and Ercc1(-/Δ) samples. An unexpectedly high number of 77 genes were differentially regulated in both WT and Ercc1(-/Δ) mice (p < 0.0001). GO term enrichment analysis revealed these genes to be involved in immune and inflammatory response, cell death, and chemotaxis. In a network analysis, these genes were part of insulin signaling, chemokine and cytokine signaling and extracellular matrix pathways. Beyond insulin signaling, we find chemokine and cytokine signaling as well as modifiers of extracellular matrix composition to be subject to major changes in the aging glomerulus. At the level of the transcriptome, the pattern of gene activities is similar in the progeroid Ercc1(-/Δ) mouse model constituting a valuable tool for future studies of aging-associated glomerular pathologies.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/20160003495','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20160003495"><span>Are Ferroan Anorthosites Direct Products of the Lunar Magma Ocean?</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Neal, C. R.; Draper, D. S.</p> <p>2016-01-01</p> <p>According to Lunar Magma Ocean (LMO) theory, lunar samples that fall into the ferroan anorthosite (FAN) category represent the only samples we have of of the primordial crust of the Moon. Modeling indicates that plagioclase crystallizes after >70% LMO crystallization and formed a flotation crust, depending upon starting composition. The FAN group of highlands materials has been subdivided into mafic-magnesian, mafic-ferroan, anorthositic- sodic, and anorthositic-ferroan, although it is not clear how these subgroups are related. Recent radiogenic isotope work has suggested the range in FAN ages and isotopic systematics are inconsistent with formation of all FANs from the LMO. While an insulating lid could have theoretically extend the life of the LMO to explain the range of the published ages, are the FAN compositions consistent with crystallization from the LMO? As part of a funded Emerging Worlds proposal (NNX15AH76G), we examine this question through analysis of FAN samples. We compare the results with various LMO crystallization models, including those that incorporate the influence of garnet.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27915081','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27915081"><span>Parental feeding practices in families with children aged 2-13 years: Psychometric properties and child age-specific norms of the German version of the Child Feeding Questionnaire (CFQ).</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Schmidt, Ricarda; Richter, Robert; Brauhardt, Anne; Hiemisch, Andreas; Kiess, Wieland; Hilbert, Anja</p> <p>2017-02-01</p> <p>The Child Feeding Questionnaire (CFQ) is a self-report questionnaire for assessing parental attitudes to child weight and parental feeding practices. Previous evaluations of its psychometric properties were conducted primarily with small to medium-sized samples (N < 500) and a small range of children's age. The present study aims to analyze the psychometric properties of the CFQ in a large German community sample and, for the first time, to establish normative data. Within the population-based LIFE Child study, the CFQ was administered to N = 982 mothers of 2- to 13-year-old children. Psychometric analyses on item statistics and internal consistency were conducted. Using structural equation modeling, four empirically-based factorial models of the CFQ were evaluated, and measurement invariance across child age groups and sex was examined. Age-specific norms for the CFQ subscales were computed. Item statistics were highly favorable for the majority of items, but floor and ceiling effects were found for 14 of 31 items. Internal consistency of the CFQ subscales ranged from acceptable to excellent (0.71 ≤ α ≤ 0.91), except for the subscale Perceived Responsibility (α = 0.65). Regarding factorial validity, an eight-factor model with the newly created Reward subscale provided the best fit to the data. This model was factorial invariant across child sex and adjacent age groups. Maternal and child weight status showed large effects on CFQ subscale scores. The analyses established good psychometric properties for the German version of the CFQ and confirmed an eight-factor model. The provided norms allow for the comparison of individual parental feeding practices and change over time. The CFQ's sensitivity to change and longitudinal associations of parental feeding practices and child weight status warrant further research. Copyright © 2016 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=satisfactory+AND+students+AND+school&pg=7&id=EJ1068048','ERIC'); return false;" href="https://eric.ed.gov/?q=satisfactory+AND+students+AND+school&pg=7&id=EJ1068048"><span>The Competence of Modelling in Learning Chemical Change: A Study with Secondary School Students</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Oliva, José Mª; del Mar Aragón, María; Cuesta, Josefa</p> <p>2015-01-01</p> <p>The competence of modelling as part of learning about chemical change is analysed in a sample of 35 secondary students, ages 14-15 years, during their study of a curricular unit on this topic. The teaching approach followed is model based, with frequent use of analogies and mechanical models (fruits and bowls, Lego pieces, balls of plasticine,…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=heritability&id=EJ1119235','ERIC'); return false;" href="https://eric.ed.gov/?q=heritability&id=EJ1119235"><span>A Twin Factor Mixture Modeling Approach to Childhood Temperament: Differential Heritability</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Scott, Brandon G.; Lemery-Chalfant, Kathryn; Clifford, Sierra; Tein, Jenn-Yun; Stoll, Ryan; Goldsmith, H.Hill</p> <p>2016-01-01</p> <p>Twin factor mixture modeling was used to identify temperament profiles while simultaneously estimating a latent factor model for each profile with a sample of 787 twin pairs (M[subscript age] = 7.4 years, SD = 0.84; 49% female; 88.3% Caucasian), using mother- and father-reported temperament. A four-profile, one-factor model fit the data well.…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28537360','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28537360"><span>Patient characteristics in relation to dental care payment model: capitation vs fee for service.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hakeberg, M; Wide Boman, U</p> <p>2016-12-01</p> <p>To analyse patient profiles in two payment models, the capitation (DCH) and the fee-for-service (FFS) systems, in relation to socioeconomic status, self-reported health and health behavior, as well as patient attitudes to and satisfaction with the DCH model in the Public Dental Service (PDS) in Sweden. The present survey included a random national sample of the adult population in Sweden. A telemarketing company, TNS SIFO, was responsible for the sample selection and telephone interviews conducted in May 2013. The 3,500 adults (aged =19 years) included in the sample gave a participation rate of 49.7%. Individuals choosing DCH were younger. FFS patients rated their health as less good, were less physically active, were more often smokers and had a lower household income. The DCH patients were more satisfied with their payment model than the FFS patients (98% vs 85%). A multivariate analysis showed that three of the variables significantly contributed to the model predicting DCH patients: age, with an odds ratio of 0.95, household income (OR=1.85) and importance of oral health for well-being (OR=2.05). There was a pattern of dimensions indicating the choice of payment model among adult patients in the Swedish Public Dental Service. The patients in DCH had higher socioeconomic position, were younger, rated their oral health as better and were more satisfied with the payment model (DCH) than the patients in the FFS system. Copyright© 2016 Dennis Barber Ltd</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25222086','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25222086"><span>Racial differences in parenting style typologies and heavy episodic drinking trajectories.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Clark, Trenette T; Yang, Chongming; McClernon, F Joseph; Fuemmeler, Bernard F</p> <p>2015-07-01</p> <p>This study examines racial differences between Whites and Blacks in the association of parenting style typologies with changes in heavy episodic drinking from adolescence to young adulthood. The analytic sample consists of 9,942 adolescents drawn from the National Longitudinal Study of Adolescent Health, which followed respondents from ages 12 to 31 years. Confirmatory factor analysis and factor mixture modeling are used to classify parenting style typologies based on measures of parental acceptance and control. Heavy Episodic Drinking (HED) trajectories are evaluated using a zero-inflated Poisson multigroup latent growth curve modeling approach. The mixture model identified 4 heterogeneous groups that differed based on the 2 latent variables (parental acceptance and control): balanced (65.8% of the sample), authoritarian (12.2%), permissive (19.4%), and uninvolved or neglectful (2.7%). Regardless of race, we found that at age 12 years, children of authoritarian parents have a higher probability of not engaging in HED than children of parents with balanced, permissive, or neglectful parenting styles. However, among Black youth who reported HED at age 12, authoritarian parenting was associated with greater level of HED at age 12 but a less steep increase in level of HED as age increased yearly as compared with balanced parenting. For White adolescents, uninvolved, permissive, and authoritarian parenting were not associated with a greater level of HED as age increased yearly as compared with adolescents exposed to balanced parenting. The influence of parenting styles on HED during adolescence persists into young adulthood and differs by race for youth engaging in HED. (c) 2015 APA, all rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4362953','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4362953"><span>Racial Differences in Parenting Style Typologies and Heavy Episodic Drinking Trajectories</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Clark, Trenette T.; Yang, Chongming; McClernon, F. Joseph; Fuemmeler, Bernard</p> <p>2014-01-01</p> <p>Objective This study examines racial differences between Caucasians and African Americans in the association of parenting style typologies with changes in heavy episodic drinking from adolescence to young adulthood. Methods The analytic sample consists of 9,942 adolescents drawn from the National Longitudinal Study of Adolescent Health, which followed respondents from ages 12 to 31 years. Confirmatory factor analysis and factor mixture modeling are used to classify parenting style typologies based on measures of parental acceptance and control. HED trajectories are evaluated using a zero-inflated Poisson multigroup latent growth curve modeling approach. Results The mixture model identified four heterogeneous groups that differed based on the two latent variables (parental acceptance and control): balanced (65.8% of the sample), authoritarian (12.2%), permissive (19.4%), and uninvolved/neglectful (2.7%). Regardless of race, we found that at age 12 years, children of authoritarian parents have a higher probability of not engaging in HED than children of parents with balanced, permissive, or neglectful parenting styles. However, among African American youth who reported HED at age 12, authoritarian parenting was associated with greater level of HED at age 12 but a less steep increase in level of HED as age increased yearly as compared with balanced parenting. For Caucasian adolescents, uninvolved, permissive, and authoritarian parenting were not associated with a greater level of HED as age increased yearly as compared with adolescents exposed to balanced parenting. Conclusion The influence of parenting styles on HED during adolescence persists into young adulthood and differs by race for youth engaging in HED. PMID:25222086</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23657410','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23657410"><span>A methodology to measure cervical vertebral bone maturation in a sample from low-income children.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Aguiar, Luciana Barreto Vieira; Caldas, Maria de Paula; Haiter Neto, Francisco; Ambrosano, Glaucia Maria Bovi</p> <p>2013-01-01</p> <p>This study evaluated the applicability of the regression method for determining vertebral age developed by Caldas et al. (2007) by testing this method in children from low-income families of the rural zone. The sample comprised cephalometric and hand-wrist radiographs of 76 boys and 64 girls aged 7.0 to 14.9 years living in a medium-sized city in the desert region of the northeastern region of Brazil, with an HDI of 0.678. C3 and C4 vertebrae were traced and measured on cephalometric radiographs to estimate the bone age. The average age, average hand-wrist age and average error estimated for girls and boys were, respectively, 10.62 and 10.44 years, 11.28 and 10.57 years, and 1.42 and 1.18 years. Based on these results, the formula proposed by Caldas et al. (2007) was not applicable to the studied population, and new multiple regression models were developed to obtain the children's vertebral bone age accurately.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26913612','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26913612"><span>Age and health jointly moderate the influence of flexible work arrangements on work engagement: Evidence from two empirical studies.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Rudolph, Cort W; Baltes, Boris B</p> <p>2017-01-01</p> <p>Research and theory support the notion that flexible work arrangements (i.e., job resources in the form of formal policies that allow employees the latitude to manage when, where, and how they work) can have a positive influence on various outcomes that are valued both by organizations and their constituents. In the present study, we integrate propositions from various theoretical perspectives to investigate how flexible work arrangements influence work engagement. Then, in 2 studies we test this association and model the influence of different conceptualizations of health and age as joint moderators of this relationship. Study 1 focuses on functional health and chronological age in an age-diverse sample, whereas study 2 focuses on health symptom severity and subjective age in a sample of older workers. In both studies, we demonstrate that the influence of flexible work arrangements on work engagement is contingent upon age and health. (PsycINFO Database Record (c) 2016 APA, all rights reserved).</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1997A%26A...319..394D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1997A%26A...319..394D"><span>Age and metallicity effects in single stellar populations: application to M 31 clusters.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>de Freitas Pacheco, J. A.</p> <p>1997-03-01</p> <p>We have recently calculated (Borges et al. 1995AJ....110.2408B) integrated metallicity indices for single stellar populations (SSP). Effects of age, metallicity and abundances were taken into account. In particular, the explicit dependence of the indices Mg_2_ and NaD respectively on the ratios [Mg/Fe] and [Na/Fe] was included in the calibration. We report in this work an application of those models to a sample of 12 globular clusters in M 31. A fitting procedure was used to obtain age, metallicity and the [Mg/Fe] ratio for each object, which best reproduce the data. The mean age of the sample is 15+/-2.8Gyr and the mean [Mg/Fe] ratio is 0.35+/-0.10. These values and the derived metallicity spread are comparable to those found in galactic counterparts.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li class="active"><span>15</span></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_15 --> <div id="page_16" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li class="active"><span>16</span></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="301"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27497774','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27497774"><span>Analysis of the Factors Affecting the Interval between Blood Donations Using Log-Normal Hazard Model with Gamma Correlated Frailties.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Tavakol, Najmeh; Kheiri, Soleiman; Sedehi, Morteza</p> <p>2016-01-01</p> <p>Time to donating blood plays a major role in a regular donor to becoming continues one. The aim of this study was to determine the effective factors on the interval between the blood donations. In a longitudinal study in 2008, 864 samples of first-time donors in Shahrekord Blood Transfusion Center, capital city of Chaharmahal and Bakhtiari Province, Iran were selected by a systematic sampling and were followed up for five years. Among these samples, a subset of 424 donors who had at least two successful blood donations were chosen for this study and the time intervals between their donations were measured as response variable. Sex, body weight, age, marital status, education, stay and job were recorded as independent variables. Data analysis was performed based on log-normal hazard model with gamma correlated frailty. In this model, the frailties are sum of two independent components assumed a gamma distribution. The analysis was done via Bayesian approach using Markov Chain Monte Carlo algorithm by OpenBUGS. Convergence was checked via Gelman-Rubin criteria using BOA program in R. Age, job and education were significant on chance to donate blood (P<0.05). The chances of blood donation for the higher-aged donors, clericals, workers, free job, students and educated donors were higher and in return, time intervals between their blood donations were shorter. Due to the significance effect of some variables in the log-normal correlated frailty model, it is necessary to plan educational and cultural program to encourage the people with longer inter-donation intervals to donate more frequently.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1998A%26A...333..505B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1998A%26A...333..505B"><span>On the relative ages of galactic globular clusters. A new observable, a semi-empirical calibration and problems with the theoretical isochrones</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Buonanno, R.; Corsi, C. E.; Pulone, L.; Fusi Pecci, F.; Bellazzini, M.</p> <p>1998-05-01</p> <p>A new procedure is described to derive homogeneous relative ages from the Color-Magnitude Diagrams (CMDs) of Galactic globular clusters (GGCs). It is based on the use of a new observable, Delta V(0.05) , namely the difference in magnitude between an arbitrary point on the upper main sequence (V_{+0.05} -the V magnitude of the MS-ridge, 0.05 mag redder than the Main Sequence (MS) Turn-off, (TO)) and the horizontal branch (HB). The observational error associated to Delta V(0.05) is substantially smaller than that of previous age-indicators, keeping the property of being strictly independent of distance and reddening and of being based on theoretical luminosities rather than on still uncertain theoretical temperatures. As an additional bonus, the theoretical models show that Delta V(0.05) has a low dependence on metallicity. Moreover, the estimates of the relative age so obtained are also sufficiently invariant (to within ~ +/- 1 Gyr) with varying adopted models and transformations. Since the difference in the color difference Delta (B-V)_{TO,RGB} (VandenBerg, Bolte and Stetson 1990 -VBS, Sarajedini and Demarque 1990 -SD) remains the most reliable technique to estimate relative cluster ages for clusters where the horizontal part of the HB is not adequately populated, we have used the differential ages obtained via the "vertical" Delta V(0.05) parameter for a selected sample of clusters (with high quality CMDs, well populated HBs, trustworthy calibrations) to perform an empirical calibration of the "horizontal" observable in terms of [Fe/H] and age. A direct comparison with the corresponding calibration derived from the theoretical models reveals the existence of clear-cut discrepancies, which call into question the model scaling with metallicity in the observational planes. Starting from the global sample of considered clusters, we have thus evaluated, within a homogeneous procedure, relative ages for 33 GGCs having different metallicity, HB-morphologies, and galactocentric distances. These new estimates have also been compared with previous latest determinations (Chaboyer, Demarque and Sarajedini 1996, and Richer {et al. } 1996). The distribution of the cluster ages with varying metallicity and galactocentric distance are briefly discussed: (a) there is no direct indication for any evident age-metallicity relationship; (b) there is some spread in age (still partially compatible with the errors), and the largest dispersion is found for intermediate metal-poor clusters; (c) older clusters populate both the inner and the outer regions of the Milky Way, while the younger globulars are present only in the outer regions, but the sample is far too poor to yield conclusive evidences.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29496281','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29496281"><span>A model combining age, equivalent uniform dose and IL-8 may predict radiation esophagitis in patients with non-small cell lung cancer.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Wang, Shulian; Campbell, Jeff; Stenmark, Matthew H; Stanton, Paul; Zhao, Jing; Matuszak, Martha M; Ten Haken, Randall K; Kong, Feng-Ming</p> <p>2018-03-01</p> <p>To study whether cytokine markers may improve predictive accuracy of radiation esophagitis (RE) in non-small cell lung cancer (NSCLC) patients. A total of 129 patients with stage I-III NSCLC treated with radiotherapy (RT) from prospective studies were included. Thirty inflammatory cytokines were measured in platelet-poor plasma samples. Logistic regression was performed to evaluate the risk factors of RE. Stepwise Akaike information criterion (AIC) and likelihood ratio test were used to assess model predictions. Forty-nine of 129 patients (38.0%) developed grade ≥2 RE. Univariate analysis showed that age, stage, concurrent chemotherapy, and eight dosimetric parameters were significantly associated with grade ≥2 RE (p < 0.05). IL-4, IL-5, IL-8, IL-13, IL-15, IL-1α, TGFα and eotaxin were also associated with grade ≥2 RE (p < 0.1). Age, esophagus generalized equivalent uniform dose (EUD), and baseline IL-8 were independently associated grade ≥2 RE. The combination of these three factors had significantly higher predictive power than any single factor alone. Addition of IL-8 to toxicity model significantly improves RE predictive accuracy (p = 0.019). Combining baseline level of IL-8, age and esophagus EUD may predict RE more accurately. Refinement of this model with larger sample sizes and validation from multicenter database are warranted. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15626935','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15626935"><span>Comparison of the predictive validity of diagnosis-based risk adjusters for clinical outcomes.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Petersen, Laura A; Pietz, Kenneth; Woodard, LeChauncy D; Byrne, Margaret</p> <p>2005-01-01</p> <p>Many possible methods of risk adjustment exist, but there is a dearth of comparative data on their performance. We compared the predictive validity of 2 widely used methods (Diagnostic Cost Groups [DCGs] and Adjusted Clinical Groups [ACGs]) for 2 clinical outcomes using a large national sample of patients. We studied all patients who used Veterans Health Administration (VA) medical services in fiscal year (FY) 2001 (n = 3,069,168) and assigned both a DCG and an ACG to each. We used logistic regression analyses to compare predictive ability for death or long-term care (LTC) hospitalization for age/gender models, DCG models, and ACG models. We also assessed the effect of adding age to the DCG and ACG models. Patients in the highest DCG categories, indicating higher severity of illness, were more likely to die or to require LTC hospitalization. Surprisingly, the age/gender model predicted death slightly more accurately than the ACG model (c-statistic of 0.710 versus 0.700, respectively). The addition of age to the ACG model improved the c-statistic to 0.768. The highest c-statistic for prediction of death was obtained with a DCG/age model (0.830). The lowest c-statistics were obtained for age/gender models for LTC hospitalization (c-statistic 0.593). The c-statistic for use of ACGs to predict LTC hospitalization was 0.783, and improved to 0.792 with the addition of age. The c-statistics for use of DCGs and DCG/age to predict LTC hospitalization were 0.885 and 0.890, respectively, indicating the best prediction. We found that risk adjusters based upon diagnoses predicted an increased likelihood of death or LTC hospitalization, exhibiting good predictive validity. In this comparative analysis using VA data, DCG models were generally superior to ACG models in predicting clinical outcomes, although ACG model performance was enhanced by the addition of age.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26301459','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26301459"><span>Kidney function changes with aging in adults: comparison between cross-sectional and longitudinal data analyses in renal function assessment.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Chung, Sang M; Lee, David J; Hand, Austin; Young, Philip; Vaidyanathan, Jayabharathi; Sahajwalla, Chandrahas</p> <p>2015-12-01</p> <p>The study evaluated whether the renal function decline rate per year with age in adults varies based on two primary statistical analyses: cross-section (CS), using one observation per subject, and longitudinal (LT), using multiple observations per subject over time. A total of 16628 records (3946 subjects; age range 30-92 years) of creatinine clearance and relevant demographic data were used. On average, four samples per subject were collected for up to 2364 days (mean: 793 days). A simple linear regression and random coefficient models were selected for CS and LT analyses, respectively. The renal function decline rates per year were 1.33 and 0.95 ml/min/year for CS and LT analyses, respectively, and were slower when the repeated individual measurements were considered. The study confirms that rates are different based on statistical analyses, and that a statistically robust longitudinal model with a proper sampling design provides reliable individual as well as population estimates of the renal function decline rates per year with age in adults. In conclusion, our findings indicated that one should be cautious in interpreting the renal function decline rate with aging information because its estimation was highly dependent on the statistical analyses. From our analyses, a population longitudinal analysis (e.g. random coefficient model) is recommended if individualization is critical, such as a dose adjustment based on renal function during a chronic therapy. Copyright © 2015 John Wiley & Sons, Ltd.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25590622','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25590622"><span>Interaction between Helicobacter pylori and latent toxoplasmosis and demographic variables on cognitive function in young to middle-aged adults.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Gale, Shawn D; Erickson, Lance D; Brown, Bruce L; Hedges, Dawson W</p> <p>2015-01-01</p> <p>Helicobacter pylori and latent toxoplasmosis are widespread diseases that have been associated with cognitive deficits and Alzheimer's disease. We sought to determine whether interactions between Helicobacter pylori and latent toxoplasmosis, age, race-ethnicity, educational attainment, economic status, and general health predict cognitive function in young and middle-aged adults. To do so, we used multivariable regression and multivariate models to analyze data obtained from the United States' National Health and Nutrition Examination Survey from the Centers for Disease Control and Prevention, which can be weighted to represent the US population. In this sample, we found that 31.6 percent of women and 36.2 percent of men of the overall sample had IgG Antibodies against Helicobacter pylori, although the seroprevalence of Helicobacter pylori varied with sociodemographic variables. There were no main effects for Helicobacter pylori or latent toxoplasmosis for any of the cognitive measures in models adjusting for age, sex, race-ethnicity, educational attainment, economic standing, and self-rated health predicting cognitive function. However, interactions between Helicobacter pylori and race-ethnicity, educational attainment, latent toxoplasmosis in the fully adjusted models predicted cognitive function. People seropositive for both Helicobacter pylori and latent toxoplasmosis - both of which appear to be common in the general population - appear to be more susceptible to cognitive deficits than are people seropositive for either Helicobacter pylori and or latent toxoplasmosis alone, suggesting a synergistic effect between these two infectious diseases on cognition in young to middle-aged adults.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23662720','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23662720"><span>Normative values of cognitive and physical function in older adults: findings from the Irish Longitudinal Study on Ageing.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kenny, Rose Anne; Coen, Robert F; Frewen, John; Donoghue, Orna A; Cronin, Hilary; Savva, George M</p> <p>2013-05-01</p> <p>To provide normative values of tests of cognitive and physical function based on a large sample representative of the population of Ireland aged 50 and older. Data were used from the first wave of The Irish Longitudinal Study on Ageing (TILDA), a prospective cohort study that includes a comprehensive health assessment. Health assessment was undertaken at one of two dedicated health assessment centers or in the study participant's home if travel was not practicable. Five thousand eight hundred ninety-seven members of a nationally representative sample of the community-living population of Ireland aged 50 and older. Those with severe cognitive impairment, dementia, or Parkinson's disease were excluded. Measurements included height and weight, normal walking speed, Timed Up-and-Go, handgrip strength, Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Color Trails Test, and bone mineral density. Normative values were estimated using generalized additive models for location shape and scale (GAMLSS) and are presented as percentiles, means, and standard deviations. Generalized additive models for location shape and scale fit the observed data well for each measure, leading to reliable estimates of normative values. Performance on all tasks decreased with age. Educational attainment was a strong determinant of performance on all cognitive tests. Tests of walking speed were dependent on height. Distribution of body mass index did not change with age, owing to simultaneous declines in weight and height. Normative values were found for tests of many aspects of cognitive and physical function based on a representative sample of the general older Irish population. © 2013, Copyright the Authors Journal compilation © 2013, The American Geriatrics Society.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=Mather&pg=2&id=ED519975','ERIC'); return false;" href="https://eric.ed.gov/?q=Mather&pg=2&id=ED519975"><span>Exploring the Relationship between Inclusive Education and Achievement: New Perspectives</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Cosier, Meghan</p> <p>2010-01-01</p> <p>This study used Multilevel Modeling (MLM) with a sample of over 1300 students with disabilities between the ages of six and nine years old nested within 180 school districts. A sample from the Pre-Elementary Education Longitudinal Study (PEELS) dataset (Institute of Education Sciences) was used to explore the relationship between hours in general…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=kaufman&pg=3&id=EJ1054110','ERIC'); return false;" href="https://eric.ed.gov/?q=kaufman&pg=3&id=EJ1054110"><span>Gender Differences in Achievement in a Large, Nationally Representative Sample of Children and Adolescents</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Scheiber, Caroline; Reynolds, Matthew R.; Hajovsky, Daniel B.; Kaufman, Alan S.</p> <p>2015-01-01</p> <p>The purpose of this study was to investigate developmental gender differences in academic achievement areas, with the primary focus on writing, using the child and adolescent portion (ages 6-21 years) of the "Kaufman Test of Educational Achievement-Second Edition, Brief Form," norming sample (N = 1,574). Path analytic models with gender,…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/17906168','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/17906168"><span>Desired lifetime and end-of-life desires across adulthood from 20 to 90: a dual-source information model.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lang, Frieder R; Baltes, Paul B; Wagner, Gert G</p> <p>2007-09-01</p> <p>How long do people want to live, and how does scientific research on aging affect such desires? A dual-source information model proposes that aging expectations and desires are informed differently by two sources: personal experiences on the one hand, and scientific and societal influences on the other. Two studies with independent German national samples explored desires regarding length of life and end of life among adults between the ages of 20 and 90. FINDINGS ARE: First, desired lifetime is consistent at around 85 years with few age differences. Second, experimental induction of good or bad news from research on aging has little effect in Study 1. Third, interest in science has moderating effects on desired lifetime in Study 2. Fourth, there is a high prevalence of a strong desire to control the "when and how" of one's death, although only 11% of the individuals completed a living will. Findings are consistent with the dual-source information model.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18547458','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18547458"><span>Modelling antecedents of blood donation motivation among non-donors of varying age and education.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lemmens, K P H; Abraham, C; Ruiter, R A C; Veldhuizen, I J T; Dehing, C J G; Bos, A E R; Schaalma, H P</p> <p>2009-02-01</p> <p>Understanding blood donation motivation among non-donors is prerequisite to effective recruitment. Two studies explored the psychological antecedents of blood donation motivation and the generalisability of a model of donation motivation across groups differing in age and educational level. An older well-educated population and a younger less well-educated population were sampled. The studies assessed the role of altruism, fear of blood/needles and donation-specific cognitions including attitudes and normative beliefs derived from an extended theory of planned behaviour (TPB). Across both samples, results showed that affective attitude, subjective norm, descriptive norm, and moral norm were the most important correlates of blood donation intentions. Self-efficacy was more important among the younger less well-educated group. Altruism was related to donation motivation but only indirectly through moral norm. Similarly, fear of blood/needles only had an indirect effect on motivation through affective attitude and self-efficacy. Additional analyses with the combined data set found no age or education moderation effects, suggesting that this core model of donation-specific cognitions can be used to inform future practical interventions recruiting new blood donors in the general population.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29083235','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29083235"><span>Comorbid Visual and Psychiatric Disabilities Among the Chinese Elderly: A National Population-Based Survey.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Guo, Chao; Wang, Zhenjie; Li, Ning; Chen, Gong; Zheng, Xiaoying</p> <p>2017-12-01</p> <p>To estimate the prevalence of, and association between, co-morbid visual and psychiatric disabilities among elderly (>65 years-of-age) persons in China. Random representative samples were obtained using multistage, stratified, cluster sampling, with probabilities proportional to size. Standard weighting procedures were used to construct sample weights that reflected this multistage, stratified cluster sampling survey scheme. Logistic regression models were used to elucidate associations between visual and psychiatric disabilities. Among the Chinese elderly, >160,000 persons have co-morbid visual and psychiatric disabilities. The weighted prevalence among this cohort is 123.7 per 100,000 persons. A higher prevalence of co-morbid visual and psychiatric disabilities was found in the oldest-old (p<0.001); women (65-79 years-of-age, p=0.001; ≥80 years-of-age, p=0.004); illiterate (65-79 years-of-age, p<0.001; ≥80 years-of-age, p=0.02); and single elders (65-79 years-of-age, p=0.01; ≥80 years-of-age, p=0.001). Presence of a visual disability was significantly associated with a higher risk of having a psychiatric disability among persons aged ≥80 years-of-age [adjusted odds ratio, 1.24; 95% confidence interval (CI), 1.03-1.54]. A significant number of Chinese elderly persons were living with co-morbid visual and psychiatric disabilities. To address the challenge of these co-morbid disorders among Chinese elders, it is incumbent upon the government to implement additional and more comprehensive prevention and rehabilitation strategies for health-care systems, reinforce health promotion among the elderly, and improve accessibility to health-care services.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3746182','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3746182"><span>Coronary artery calcium distributions in older persons in the AGES-Reykjavik study</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Gudmundsson, Elias Freyr; Gudnason, Vilmundur; Sigurdsson, Sigurdur; Launer, Lenore J.; Harris, Tamara B.; Aspelund, Thor</p> <p>2013-01-01</p> <p>Coronary Artery Calcium (CAC) is a sign of advanced atherosclerosis and an independent risk factor for cardiac events. Here, we describe CAC-distributions in an unselected aged population and compare modelling methods to characterize CAC-distribution. CAC is difficult to model because it has a skewed and zero inflated distribution with over-dispersion. Data are from the AGES-Reykjavik sample, a large population based study [2002-2006] in Iceland of 5,764 persons aged 66-96 years. Linear regressions using logarithmic- and Box-Cox transformations on CAC+1, quantile regression and a Zero-Inflated Negative Binomial model (ZINB) were applied. Methods were compared visually and with the PRESS-statistic, R2 and number of detected associations with concurrently measured variables. There were pronounced differences in CAC according to sex, age, history of coronary events and presence of plaque in the carotid artery. Associations with conventional coronary artery disease (CAD) risk factors varied between the sexes. The ZINB model provided the best results with respect to the PRESS-statistic, R2, and predicted proportion of zero scores. The ZINB model detected similar numbers of associations as the linear regression on ln(CAC+1) and usually with the same risk factors. PMID:22990371</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29875074','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29875074"><span>Discovering human germ cell mutagens with whole genome sequencing: Insights from power calculations reveal the importance of controlling for between-family variability.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Webster, R J; Williams, A; Marchetti, F; Yauk, C L</p> <p>2018-07-01</p> <p>Mutations in germ cells pose potential genetic risks to offspring. However, de novo mutations are rare events that are spread across the genome and are difficult to detect. Thus, studies in this area have generally been under-powered, and no human germ cell mutagen has been identified. Whole Genome Sequencing (WGS) of human pedigrees has been proposed as an approach to overcome these technical and statistical challenges. WGS enables analysis of a much wider breadth of the genome than traditional approaches. Here, we performed power analyses to determine the feasibility of using WGS in human families to identify germ cell mutagens. Different statistical models were compared in the power analyses (ANOVA and multiple regression for one-child families, and mixed effect model sampling between two to four siblings per family). Assumptions were made based on parameters from the existing literature, such as the mutation-by-paternal age effect. We explored two scenarios: a constant effect due to an exposure that occurred in the past, and an accumulating effect where the exposure is continuing. Our analysis revealed the importance of modeling inter-family variability of the mutation-by-paternal age effect. Statistical power was improved by models accounting for the family-to-family variability. Our power analyses suggest that sufficient statistical power can be attained with 4-28 four-sibling families per treatment group, when the increase in mutations ranges from 40 to 10% respectively. Modeling family variability using mixed effect models provided a reduction in sample size compared to a multiple regression approach. Much larger sample sizes were required to detect an interaction effect between environmental exposures and paternal age. These findings inform study design and statistical modeling approaches to improve power and reduce sequencing costs for future studies in this area. Crown Copyright © 2018. Published by Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3174021','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3174021"><span>Childhood Risk Factors for Early-Onset Drinking*</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Donovan, John E.; Molina, Brooke S. G.</p> <p>2011-01-01</p> <p>Objective: There is relatively little research on the childhood antecedent predictors of early-onset alcohol use. This study examined an array of psychosocial variables assessed at age 10 and reflecting Problem Behavior Theory as potential antecedent risk factors for the initiation of alcohol use at age 14 or younger. Method: A sample of 452 children (238 girls) ages 8 or 10 and their families was drawn from Allegheny County, PA, using targeted-age directory sampling and random-digit dialing procedures. Children and parents were interviewed using computer-assisted interviews. Logistic regression analyses were used to examine the age-10 univariate and multivariate predictors of the initiation of alcohol use by age 14 or younger. Results: Twenty-five percent of the sample reported having more than a sip or a taste of alcohol in their life by age 14. Sex, race, and age cohort did not relate to early drinking status. Children with two parents were less likely to initiate drinking early. Early initiation of drinking related significantly to an array of antecedent risk factors (personality, social environment, and behavioral) assessed at age 10 that reflect psychosocial proneness for problem behavior. In the multivariate model, the variables most predictive of early-onset drinking were having a single parent, sipping or tasting alcohol by age 10, having parents who also started drinking at an early age, and parental drinking frequency. Conclusions: Initiation of alcohol use by age 14 reflects childhood psychosocial proneness to engage in problem behavior as measured by Problem Behavior Theory and having a family environment conducive to alcohol use. PMID:21906502</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/1158665','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/1158665"><span>Summary Report of Cable Aging and Performance Data for Fiscal Year 2014.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Celina, Mathias C.; Celina, Mathias C.; Redline, Erica Marie</p> <p>2014-09-01</p> <p>As part of the Light Water Reactor Sustainability Program, science - based engineering approaches were employed to address cable degradation behavior under a range of exposure environments. Experiments were conducted with the goal to provide best guidance for aged material states, remaining life and expected performance under specific conditions for a range of cable materials. Generic engineering tests , which focus on rapid accelerated aging and tensile elongation , were combined with complementar y methods from polymer degradation science. Sandia's approach, building on previous years' efforts, enabled the generation of some of the necessary data supporting the development of improvedmore » lifetime predictions models, which incorporate known material b ehaviors and feedback from field - returned 'aged' cable materials. Oxidation rate measurements have provided access to material behavior under low dose rate thermal conditions, where slow degradation is not apparent in mechanical property changes. Such da ta have shown aging kinetics consistent with established radiati on - thermal degradation models. ACKNOWLEDGEMENTS We gratefully acknowledge ongoing technical support at the LICA facility and extensive sample handling provided by Maryla Wasiolek and Don Hans on. Sam Durbin and Patrick Mattie are recognized for valuable guidance throughout the year and assistance in the preparation of the final report. Doug Brunson is appreciated for sample analysis, compilation and plotting of experimental data.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25903227','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25903227"><span>Variation of hair cortisol concentrations among wild populations of two baboon species (Papio anubis, P. hamadryas) and a population of their natural hybrids.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Fourie, Nicolaas H; Jolly, Clifford J; Phillips-Conroy, Jane E; Brown, Janine L; Bernstein, Robin M</p> <p>2015-07-01</p> <p>Male olive (Papio anubis) and hamadryas (P. hamadryas) baboons have distinctive sociobehavioral and physical characteristics. In the Awash National Park, Ethiopia, a hybrid population at the contact zone between these two species, exhibits heterogeneous sociobehavioral and physical characteristics. The ambiguity of the hybrid social environment and disruption of parental stress genotypes may be sources of physiological stress for hybrids. We examined levels of chronic stress among males of the three populations and tested the prediction that chronic cortisol levels would be higher among the hybrids. Animals were captured, sampled, and released during the wet season, and a hair sample was taken for assay. Cortisol was extracted from 182 hair samples with methanol and quantified by ELISA. We included age, age class, rainfall variation, and species affiliation in models examining variation in hair cortisol levels. Species and age significantly contributed to models explaining variation in hair cortisol. Infant hypercortisolism was observed in all three groups, and a decline in cortisol through juvenile and adolescent stages, with a subsequent rise in adulthood. This rise occurred earliest in hamadryas, corroborating other evidence of the precocious development of hamadryas baboons. As expected, hybrids had significantly elevated hair cortisol compared with olive baboons and hamadryas, irrespective of age, except for very young animals. Infant hypercortisolism was also less pronounced among hybrids. Species differences and age-related differences in cortisol levels suggest a dysregulated cortisol phenotype in hybrids, and possibly reflect some form of hybrid disadvantage. More work will be required to disentangle the effects of genetic factors and the social environment.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25024105','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25024105"><span>Family ties: maternal-offspring attachment and young adult nonmedical prescription opioid use.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Cerdá, M; Bordelois, P; Keyes, K M; Roberts, A L; Martins, S S; Reisner, S L; Austin, S B; Corliss, H L; Koenen, K C</p> <p>2014-09-01</p> <p>Nonmedical prescription drug use is prevalent among young adults, yet little is known about modifiable determinants of use. We examined whether maternal-offspring attachment reported at mean age 21 was associated with nonmedical prescription opioid use at mean age 26, and investigated whether a history of depressive symptoms and substance use played a role in associations between maternal-offspring attachment and nonmedical prescription opioid use. We used data from the Growing Up Today Study, a longitudinal cohort of United States adolescents followed into young adulthood. Maternal-offspring attachment was reported by young adults and their mothers, and defined as mutual low, mutual medium or high, and dissonant. Analyses were carried out in the full sample using generalized estimating equation models, and in a sibling subsample, using conditional fixed effects models to control for stable aspects of the family environment. Analyses with the full sample and the sibling subsample both showed that mutual medium/high maternal-offspring attachment at age 21 was associated with lower odds of nonmedical prescription opioid use at age 26 (RR=0.74; 95% CI=0.57-0.97 in full sample). The association was partly mediated by mean age 23 offspring smoking, heavy episodic drinking, and illicit drug use. Promoting reciprocal attachment in the maternal-offspring dyad should be investigated as a strategy to prevent nonmedical prescription opioid use by young adulthood. Even in young adulthood, programs that target both parents and offspring may have greater impact on offspring substance use than programs that target offspring alone. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4134317','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4134317"><span>Family ties: maternal-offspring attachment and young adult nonmedical prescription opioid use</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Cerdá, M.; Bordelois, P.; Keyes, K.M.; Roberts, A.L.; Martins, S.S.; Reisner, S.L.; Austin, S.B.; Corliss, H.L.; Koenen, K.C.</p> <p>2014-01-01</p> <p>Background Nonmedical prescription drug use is prevalent among young adults, yet little is known about modifiable determinants of use. We examined whether maternal-offspring attachment reported at mean age 21 was associated with nonmedical prescription opioid use at mean age 26, and investigated whether a history of depressive symptoms and substance use played a role in associations between maternal-offspring attachment and nonmedical prescription opioid use. Methods We used data from the Growing Up Today Study, a longitudinal cohort of United States adolescents followed into young adulthood. Maternal-offspring attachment was reported by young adults and their mothers, and defined as mutual low, mutual medium or high, and dissonant. Analyses were carried out in the full sample using generalized estimating equation models, and in a sibling subsample, using conditional fixed effects models to control for stable aspects of the family environment. Results Analyses with the full sample and the sibling subsample both showed that mutual medium/high maternal-offspring attachment at age 21 was associated with lower odds of nonmedical prescription opioid use at age 26 (RR=0.74; 95% CI=0.57-0.97 in full sample). The association was partly mediated by mean age 23 offspring smoking, heavy episodic drinking, and illicit drug use. Conclusions Promoting reciprocal attachment in the maternal-offspring dyad should be investigated as a strategy to prevent nonmedical prescription opioid use by young adulthood. Even in young adulthood, programs that target both parents and offspring may have greater impact on offspring substance use than programs that target offspring alone. PMID:25024105</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018IJEaS.107..459G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018IJEaS.107..459G"><span>Detrital thermochronology of Rhine, Elbe and Meuse river sediment (Central Europe): implications for provenance, erosion and mineral fertility</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Glotzbach, C.; Busschers, F. S.; Winsemann, J.</p> <p>2018-03-01</p> <p>Here we present detrital apatite fission track (AFT), zircon fission track (ZFT) and a few apatite (U-Th)/He (AHe) data of Middle Pleistocene to modern Rhine, Meuse and Elbe river sediments in order to resolve processes that control detrital age distributions (provenance, erosion and mineral fertility). We used a modelling approach to compare observed with theoretically predicted age distributions from an interpolated in situ AFT and ZFT age map. In situ cooling ages do show large differences in the Rhine drainage basin, facilitating the differentiation between different source regions. Inconsistencies between observed and theoretical age distributions of the Meuse and Elbe samples can be explained by mixing and reworking of sediments with different provenances (Meuse Middle Pleistocene terrace sediment) and a yet unexplored source region with old AFT ages (Elbe samples). Overall, the results show that detrital thermochronology is capable of identifying the provenance of Middle Pleistocene to modern sediments. The AFT age distributions of Rhine sediments are dominated ( 70%) by AFT ages representing the Alps. A possible explanation is higher erosion rates in the Alps as compared to areas outside the Alps. A Late Pleistocene sample from the Upper Rhine Graben contains apatite grains from the Molasse and Hegau volcanics, which we explain with a shift of the headwaters of the Rhine to the north as a result of intense Middle Pleistocene Riss glaciation. Contrary to the observed dominance of Alpine-derived AFT ages in Rhine sediments, the relative contribution of zircon ages with sources in the Alps is lower and significantly decreases downstream, suggesting a major source of zircons outside the Alps. This can be explained by increased zircon fertility of sediments derived from the Rhenish massif. Therefore, we conclude that erosion and mineral fertility are the main processes controlling detrital AFT and ZFT age distributions of the sampled river sediment. In case of the Rhine samples, AFT age distributions are mainly controlled by differences in erosion rates, whereas this impact is completely balanced by differences in mineral fertility for the ZFT data.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li class="active"><span>16</span></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_16 --> <div id="page_17" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li class="active"><span>17</span></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="321"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27757576','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27757576"><span>Immunohistochemical detection of intrathrombotic fibrocytes and its application to thrombus age estimation in murine deep vein thrombosis model.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Nosaka, Mizuho; Ishida, Yuko; Kimura, Akihiko; Kawaguchi, Takashi; Yamamoto, Hiroki; Kuninaka, Yumi; Kondo, Toshikazu</p> <p>2017-01-01</p> <p>Deep vein thrombi are dissolved after fibrosis process along with an increase of thrombus age. Fibrocytes are circulating bone marrow-derived cells with mesenchymal features that potentially have a unique and critical function in fibrosis. In this study, a double-color immunofluorescence analysis was carried out by using anti-CD45 and anti-collagen type I antibodies to examine the time-dependent appearance of fibrocytes in the murine model of stasis-induced deep vein thrombosis. The thrombus ages were 1, 3, 5, 7, 10, 14, and 21 days. In a thrombus age of less than 5 days, CD45 + and collagen type I + fibrocytes were never detected. The intrathrombotic fibrocytes were initially observed in thrombi aged 7 days, and their number increased with advances in thrombus age. In a quantitative morphometrical analysis, the average number of intrathrombotic fibrocytes was highest in 14-day-old thrombi, and all of the five samples aged 14 days had the fibrocyte number of more than 25, and in three out of them, the number of intrathrombotic fibrocytes was over 30. On the contrary, in all of thrombus samples with the postligation intervals of 10 and 21 days, the number of intrathrombotic fibrocytes was less than 25. These observations imply that thrombi containing fibrocytes are at least 7 days old and that a fibrocyte number exceeding 30 would indicate the thrombus age of approximately 14 days. Our observations indicate that the detection of fibrocytes could be useful for thrombus age determination.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=M.+AND+Wagner&pg=4&id=EJ1052222','ERIC'); return false;" href="https://eric.ed.gov/?q=M.+AND+Wagner&pg=4&id=EJ1052222"><span>Developmental Relations between Vocabulary Knowledge and Reading Comprehension: A Latent Change Score Modeling Study</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Quinn, Jamie M.; Wagner, Richard K.; Petscher, Yaacov; Lopez, Danielle</p> <p>2015-01-01</p> <p>The present study followed a sample of first-grade (N = 316, M[subscript age] = 7.05 at first test) through fourth-grade students to evaluate dynamic developmental relations between vocabulary knowledge and reading comprehension. Using latent change score modeling, competing models were fit to the repeated measurements of vocabulary knowledge and…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=health+AND+psychology&pg=7&id=EJ914981','ERIC'); return false;" href="https://eric.ed.gov/?q=health+AND+psychology&pg=7&id=EJ914981"><span>Testicular Self-Examination: A Test of the Health Belief Model and the Theory of Planned Behaviour</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>McClenahan, Carol; Shevlin, Mark; Adamson, Gary; Bennett, Cara; O'Neill, Brenda</p> <p>2007-01-01</p> <p>The aim of this study was to test the utility and efficiency of the theory of planned behaviour (TPB) and the health belief model (HBM) in predicting testicular self-examination (TSE) behaviour. A questionnaire was administered to an opportunistic sample of 195 undergraduates aged 18-39 years. Structural equation modelling indicated that, on the…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=pathology&pg=7&id=EJ891722','ERIC'); return false;" href="https://eric.ed.gov/?q=pathology&pg=7&id=EJ891722"><span>Body Dissatisfaction and Eating Disturbances in Early Adolescence: A Structural Modeling Investigation Examining Negative Affect and Peer Factors</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Hutchinson, Delyse M.; Rapee, Ronald M.; Taylor, Alan</p> <p>2010-01-01</p> <p>This study tested five proposed models of the relationship of negative affect and peer factors in early adolescent body dissatisfaction, dieting, and bulimic behaviors. A large community sample of girls in early adolescence was assessed via questionnaire (X[overbar] age = 12.3 years). Structural equation modeling (SEM) indicated that negative…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27867259','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27867259"><span>Personality and Other Lifelong Influences on Older-Age Health and Wellbeing: Preliminary Findings in Two Scottish Samples.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Harris, Mathew A; Brett, Caroline E; Starr, John M; Deary, Ian J; Johnson, Wendy</p> <p>2016-01-01</p> <p>Recent observations that personality traits are related to later-life health and wellbeing have inspired considerable interest in exploring the mechanisms involved. Other factors, such as cognitive ability and education, also show longitudinal influences on health and wellbeing, but it is not yet clear how all these early-life factors together contribute to later-life health and wellbeing. In this preliminary study, we assessed hypothesised relations among these variables across the life course, using structural equation modelling in a sample assessed on dependability (a personality trait related to conscientiousness) in childhood, cognitive ability and social class in childhood and older age, education, and health and subjective wellbeing in older age. Our models indicated that both health and subjective wellbeing in older age were influenced by childhood IQ and social class, via education. Some older-age personality traits mediated the effects of early-life variables, on subjective wellbeing in particular, but childhood dependability did not show significant associations. Our results therefore did not provide evidence that childhood dependability promotes older-age health and wellbeing, but did highlight the importance of other early-life factors, particularly characteristics that contribute to educational attainment. Further, personality in later life may mediate the effects of early-life factors on health and subjective wellbeing. © 2016 The Authors. European Journal of Personality published by John Wiley & Sons Ltd on behalf of European Association of Personality Psychology.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22663336-next-generation-virgo-cluster-survey-ngvs-xxvi-issues-photometric-age-metallicity-estimates-globular-clusters','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22663336-next-generation-virgo-cluster-survey-ngvs-xxvi-issues-photometric-age-metallicity-estimates-globular-clusters"><span></span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Powalka, Mathieu; Lançon, Ariane; Duc, Pierre-Alain</p> <p></p> <p>Large samples of globular clusters (GC) with precise multi-wavelength photometry are becoming increasingly available and can be used to constrain the formation history of galaxies. We present the results of an analysis of Milky Way (MW) and Virgo core GCs based on 5 optical-near-infrared colors and 10 synthetic stellar population models. For the MW GCs, the models tend to agree on photometric ages and metallicities, with values similar to those obtained with previous studies. When used with Virgo core GCs, for which photometry is provided by the Next Generation Virgo cluster Survey (NGVS), the same models generically return younger ages.more » This is a consequence of the systematic differences observed between the locus occupied by Virgo core GCs and models in panchromatic color space. Only extreme fine-tuning of the adjustable parameters available to us can make the majority of the best-fit ages old. Although we cannot exclude that the formation history of the Virgo core may lead to more conspicuous populations of relatively young GCs than in other environments, we emphasize that the intrinsic properties of the Virgo GCs are likely to differ systematically from those assumed in the models. Thus, the large wavelength coverage and photometric quality of modern GC samples, such as those used here, is not by itself sufficient to better constrain the GC formation histories. Models matching the environment-dependent characteristics of GCs in multi-dimensional color space are needed to improve the situation.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AGUFMNH34A..06P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AGUFMNH34A..06P"><span>Verifying the new luminescence surface-exposure dating technique--rock falls in Canyonlands National Park, Utah</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Pederson, J. L.; Sohbati, R.; Murray, A. S.; Jain, M.</p> <p>2015-12-01</p> <p>Recent studies have helped develop the optically stimulated luminescence (OSL) dating of rock surfaces, as applied to the age of the famous Great Gallery rock art panel in Canyonlands National Park. Chapot et al. (2012) dated a key rock fall to ~900 yrs ago by applying OSL to the outer 1-mm buried surface of a sandstone talus boulder, an age confirmed by independent radiocarbon dating. Later, in a novel approach and with the use of a local known-age calibration sample, Sohbati et al. (2012) modelled the millimeter-scale OSL-depth profile to determine a pre-burial exposure duration of ~700 years for the same rock fall. This combination of rock-fall dating and exposure dating--an approach with broad potential to date Holocene mass movements--constrains the creation of the Great Gallery rock art to a time window of 900 to ~1600 years ago (Pederson et al., 2014), a result met with some controversy. Here we report on a new phase of research to verify these results and further refine OSL-profile exposure dating for mass movements. New analyses from within and near the Great Gallery alcove include: i) exposure dating of the same alcove surface upon which the rock art is painted with a predicted exposure age of ~1600 years; ii) exposure dating of the top (light-exposed) side of the same rock-fall boulder whose buried side was previously dated to test for reproduction of the known age; and iii) an improved calibration sample from a nearby trail/road-cut for verification. The residual OSL signal is measured with depth in millimeter-thick increments of all samples. We first determine the site-specific luminescence reduction rate at the rock surface by fitting the OSL surface-exposure dating model to the calibration profile from the trail/road-cut. This parameterized model then provides exposure ages for the bleaching profiles observed in the other samples. Results have implications for the application of OSL rock-surface and exposure-profile dating in other settings where quartz-rich rock is available. We discuss how the light-exposed top and buried underside of clasts can be used in tandem for calibration. The technique has particular relevance to younger timescales over which cosmogenic nuclides are of limited application.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014AGUFM.T23A4642A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014AGUFM.T23A4642A"><span>Low-Temperature Thermochronology of Laramide Ranges in Montana and Wyoming Provides Information on Exhumation and Tectonics Associated with Flat-Slab Subduction</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Armenta, M.; Carrapa, B.; DeCelles, P. G.</p> <p>2014-12-01</p> <p>Timing of exhumation of Laramide basement uplifts can be used as a proxy for tectonic processes associated with thick-skinned deformation resulting from flat-slab subduction. Despite its significance, the timing and pattern of Laramide deformation remains poorly constrained in Montana. Thermochronological data from Wyoming indicate exhumation of Laramide ranges during the late Cretaceous and Paleogene. Whereas a few data exist for the Bearthooth Range in Montana; the exhumation history of most of the Montana ranges remains unexplored preventing testing of current tectonic models. We report apatite fission track thermochronologic (AFT) data from modern river sands derived from Laramide ranges, bedrock basement samples, and synorogenic conglomerate clasts to determine the regional exhumation history of the Beartooth, Gravelly, Tobacco Root, Ruby, the Highland Mountains, and the Wind River Range. AFT permits reconstruction of thermal histories and rates of erosion of the upper few kilometers of the crust. In particular detrital AFT of river sands provides information on regional exhumation of the drainage area. AFT detrital ages derived from the southern end of the Beartooth Range are dominated by a 60-80 Ma signal, consistent with ages reported for bedrock basement samples in the Beartooth Range. A Cenozoic synorogenic conglomerate clast was obtained from the Highland Mountains, AFT results show a 69.56 +/- 5.45 Ma cooling age. In the Wind River Range, Wyoming AFT data from a Cenozoic synorogenic conglomerate clast from the Wind River Formation indicates a 59.32 +/- 4.83 Ma cooling age. This age is consistent with AFT ages from Gannett Peak indicating rapid cooling at ~60 Ma and ~50 Ma (Fan and Carrapa, 2014). Overall, samples from the easternmost ranges, the Beartooth and Bighorn, clearly preserve a Cretaceous signal; samples from Wind River Range and the rest of southwest Montana mainly record a Cenozoic signal. This suggests deeper and younger exhumation to the west than to the east. These results combined with thermal modeling provide additional constraints on the tectono-thermal history of Laramide ranges. In addition, these results allow for a temporal-spatial comparison between cooling and exhumation in the Montana and Wyoming Laramide regions and help test current models of the Laramide Orogeny.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27540286','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27540286"><span>The social network index and its relation to later-life depression among the elderly aged ≥80 years in Northern Thailand.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Aung, Myo Nyein; Moolphate, Saiyud; Aung, Thin Nyein Nyein; Katonyoo, Chitima; Khamchai, Songyos; Wannakrairot, Pongsak</p> <p>2016-01-01</p> <p>Having a diverse social network is considered to be beneficial to a person's well-being. The significance, however, of social network diversity in the geriatric assessment of people aged ≥80 years has not been adequately investigated within the Southeast Asian context. This study explored the social networks belonging to the elderly aged ≥80 years and assessed the relation of social network and geriatric depression. This study was a community-based cross-sectional survey conducted in Chiang Mai Province, Northern Thailand. A representative sample of 435 community residents, aged ≥80 years, were included in a multistage sample. The participants' social network diversity was assessed by applying Cohen's social network index (SNI). The geriatric depression scale and activities of daily living measures were carried out during home visits. Descriptive analyses revealed the distribution of SNI, while the relationship between the SNI and the geriatric depression scale was examined by ordinal logistic regression models controlling possible covariants such as age, sex, and educational attainment. The median age of the sample was 83 years, with females comprising of 54.94% of the sample. The participants' children, their neighbors, and members of Buddhist temples were reported as the most frequent contacts of the study participants. Among the 435 participants, 25% were at risk of social isolation due to having a "limited" social network group (SNI 0-3), whereas 37% had a "medium" social network (SNI 4-5), and 38% had a "diverse" social network (SNI ≥6). The SNI was not different among the two sexes. Activities of daily living scores in the diverse social network group were significantly higher than those in the limited social network group. Multivariate ordinal logistic regression analysis models revealed a significant negative association between social network diversity and geriatric depression. Regular and frequent contact with various social contacts may safeguard common geriatric depression among persons aged ≥80 years. As a result, screening those at risk of social isolation is recommended to be integrated into routine primary health care-based geriatric assessment and intervention programs.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4905965','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4905965"><span>Progressive Bidirectional Age-Related Changes in Default Mode Network Effective Connectivity across Six Decades</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Li, Karl; Laird, Angela R.; Price, Larry R.; McKay, D. Reese; Blangero, John; Glahn, David C.; Fox, Peter T.</p> <p>2016-01-01</p> <p>The default mode network (DMN) is a set of regions that is tonically engaged during the resting state and exhibits task-related deactivation that is readily reproducible across a wide range of paradigms and modalities. The DMN has been implicated in numerous disorders of cognition and, in particular, in disorders exhibiting age-related cognitive decline. Despite these observations, investigations of the DMN in normal aging are scant. Here, we used blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) acquired during rest to investigate age-related changes in functional connectivity of the DMN in 120 healthy normal volunteers comprising six, 20-subject, decade cohorts (from 20–29 to 70–79). Structural equation modeling (SEM) was used to assess age-related changes in inter-regional connectivity within the DMN. SEM was applied both using a previously published, meta-analytically derived, node-and-edge model, and using exploratory modeling searching for connections that optimized model fit improvement. Although the two models were highly similar (only 3 of 13 paths differed), the sample demonstrated significantly better fit with the exploratory model. For this reason, the exploratory model was used to assess age-related changes across the decade cohorts. Progressive, highly significant changes in path weights were found in 8 (of 13) paths: four rising, and four falling (most changes were significant by the third or fourth decade). In all cases, rising paths and falling paths projected in pairs onto the same nodes, suggesting compensatory increases associated with age-related decreases. This study demonstrates that age-related changes in DMN physiology (inter-regional connectivity) are bidirectional, progressive, of early onset and part of normal aging. PMID:27378909</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27378909','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27378909"><span>Progressive Bidirectional Age-Related Changes in Default Mode Network Effective Connectivity across Six Decades.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Li, Karl; Laird, Angela R; Price, Larry R; McKay, D Reese; Blangero, John; Glahn, David C; Fox, Peter T</p> <p>2016-01-01</p> <p>The default mode network (DMN) is a set of regions that is tonically engaged during the resting state and exhibits task-related deactivation that is readily reproducible across a wide range of paradigms and modalities. The DMN has been implicated in numerous disorders of cognition and, in particular, in disorders exhibiting age-related cognitive decline. Despite these observations, investigations of the DMN in normal aging are scant. Here, we used blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) acquired during rest to investigate age-related changes in functional connectivity of the DMN in 120 healthy normal volunteers comprising six, 20-subject, decade cohorts (from 20-29 to 70-79). Structural equation modeling (SEM) was used to assess age-related changes in inter-regional connectivity within the DMN. SEM was applied both using a previously published, meta-analytically derived, node-and-edge model, and using exploratory modeling searching for connections that optimized model fit improvement. Although the two models were highly similar (only 3 of 13 paths differed), the sample demonstrated significantly better fit with the exploratory model. For this reason, the exploratory model was used to assess age-related changes across the decade cohorts. Progressive, highly significant changes in path weights were found in 8 (of 13) paths: four rising, and four falling (most changes were significant by the third or fourth decade). In all cases, rising paths and falling paths projected in pairs onto the same nodes, suggesting compensatory increases associated with age-related decreases. This study demonstrates that age-related changes in DMN physiology (inter-regional connectivity) are bidirectional, progressive, of early onset and part of normal aging.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.fs.usda.gov/treesearch/pubs/39989','TREESEARCH'); return false;" href="https://www.fs.usda.gov/treesearch/pubs/39989"><span>Crown structure and growth efficiency of red spruce in uneven-aged, mixed-species stands in Maine</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.fs.usda.gov/treesearch/">Treesearch</a></p> <p>Douglas A. Maguire; John C. Brissette; Lianhong. Gu</p> <p>1998-01-01</p> <p>Several hypotheses about the relationships among individual tree growth, tree leaf area, and relative tree size or position were tested with red spruce (Picea rubens Sarg.) growing in uneven-aged, mixed-species forests of south-central Maine, U.S.A. Based on data from 65 sample trees, predictive models were developed to (i)...</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=family+AND+organizational+AND+research&pg=7&id=EJ882197','ERIC'); return false;" href="https://eric.ed.gov/?q=family+AND+organizational+AND+research&pg=7&id=EJ882197"><span>Internet Use and Social Networking among Middle Aged and Older Adults</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Hogeboom, David L.; McDermott, Robert J.; Perrin, Karen M.; Osman, Hana; Bell-Ellison, Bethany A.</p> <p>2010-01-01</p> <p>In this study, the associations between Internet use and the social networks of adults over 50 years of age were examined. A sample (n = 2284) from the 2004 wave of the "Health and Retirement Survey" was used. In regression models considering a number of control variables, frequency of contact with friends, frequency of contact with family, and…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=harsh+AND+parenting+AND+adolescent+AND+depression&id=EJ725490','ERIC'); return false;" href="https://eric.ed.gov/?q=harsh+AND+parenting+AND+adolescent+AND+depression&id=EJ725490"><span>Childhood Temperament and Family Environment as Predictors of Internalizing and Externalizing Trajectories from Ages 5 to 17</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Leve, Leslie D.; Kim, Hyoun K.; Pears, Katherine C.</p> <p>2005-01-01</p> <p>Childhood temperament and family environment have been shown to predict internalizing and externalizing behavior; however, less is known about how temperament and family environment interact to predict changes in problem behavior. We conducted latent growth curve modeling on a sample assessed at ages 5, 7, 10, 14, and 17 (N = 337). Externalizing…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=dsm+AND+v&pg=2&id=EJ967911','ERIC'); return false;" href="https://eric.ed.gov/?q=dsm+AND+v&pg=2&id=EJ967911"><span>The Structure of Autism Symptoms as Measured by the Autism Diagnostic Observation Schedule</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Norris, Megan; Lecavalier, Luc; Edwards, Michael C.</p> <p>2012-01-01</p> <p>The current study tested several competing models of the autism phenotype using data from modules 1 and 3 of the ADOS. Participants included individuals with ASDs aged 3-18 years (N = 1,409) from the AGRE database. Confirmatory factor analyses were performed on total samples and subsamples based on age and level of functioning. Three primary…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=parenting+AND+style+AND+discipline&pg=6&id=EJ833761','ERIC'); return false;" href="https://eric.ed.gov/?q=parenting+AND+style+AND+discipline&pg=6&id=EJ833761"><span>The Influence of Maternal Acculturation, Neighborhood Disadvantage, and Parenting on Chinese American Adolescents' Conduct Problems: Testing the Segmented Assimilation Hypothesis</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Liu, Lisa L.; Lau, Anna S.; Chen, Angela Chia-Chen; Dinh, Khanh T.; Kim, Su Yeong</p> <p>2009-01-01</p> <p>Associations among neighborhood disadvantage, maternal acculturation, parenting and conduct problems were investigated in a sample of 444 Chinese American adolescents. Adolescents (54% female, 46% male) ranged from 12 to 15 years of age (mean age = 13.0 years). Multilevel modeling was employed to test the hypothesis that the association between…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=Optimism&pg=2&id=EJ1145549','ERIC'); return false;" href="https://eric.ed.gov/?q=Optimism&pg=2&id=EJ1145549"><span>The Association of Age, Sense of Control, Optimism, and Self-Esteem with Emotional Distress</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Jiménez, M. Guadalupe; Montorio, Ignacio; Izal, María</p> <p>2017-01-01</p> <p>The aim of this study was to test a model of emotional distress, which incorporates the potential mediator role of positive resources (sense of control, self-esteem, and optimism) in the association of age with emotional distress. The study used a cross-sectional design with intentional sampling and the voluntary participation of 325 adults…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018InPhT..89..247N','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018InPhT..89..247N"><span>A bench-top hyperspectral imaging system to classify beef from Nellore cattle based on tenderness</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Nubiato, Keni Eduardo Zanoni; Mazon, Madeline Rezende; Antonelo, Daniel Silva; Calkins, Chris R.; Naganathan, Govindarajan Konda; Subbiah, Jeyamkondan; da Luz e Silva, Saulo</p> <p>2018-03-01</p> <p>The aim of this study was to evaluate the accuracy of classification of Nellore beef aged for 0, 7, 14, or 21 days and classification based on tenderness and aging period using a bench-top hyperspectral imaging system. A hyperspectral imaging system (λ = 928-2524 nm) was used to collect hyperspectral images of the Longissimus thoracis et lumborum (aging n = 376 and tenderness n = 345) of Nellore cattle. The image processing steps included selection of region of interest, extraction of spectra, and indentification and evalution of selected wavelengths for classification. Six linear discriminant models were developed to classify samples based on tenderness and aging period. The model using the first derivative of partial absorbance spectra (give wavelength range spectra) was able to classify steaks based on the tenderness with an overall accuracy of 89.8%. The model using the first derivative of full absorbance spectra was able to classify steaks based on aging period with an overall accuracy of 84.8%. The results demonstrate that the HIS may be a viable technology for classifying beef based on tenderness and aging period.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21762180','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21762180"><span>Testing a level of response to alcohol-based model of heavy drinking and alcohol problems in 1,905 17-year-olds.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Schuckit, Marc A; Smith, Tom L; Heron, Jon; Hickman, Matthew; Macleod, John; Lewis, Glyn; Davis, John M; Hibbeln, Joseph R; Brown, Sandra; Zuccolo, Luisa; Miller, Laura L; Davey-Smith, George</p> <p>2011-10-01</p> <p>The low level of response (LR) to alcohol is one of several genetically influenced characteristics that increase the risk for heavy drinking and alcohol problems. Efforts to understand how LR operates through additional life influences have been carried out primarily in modest-sized U.S.-based samples with limited statistical power, raising questions about generalizability and about the importance of components with smaller effects. This study evaluates a full LR-based model of risk in a large sample of adolescents from the United Kingdom. Cross-sectional structural equation models were used for the approximate first half of the age 17 subjects assessed by the Avon Longitudinal Study of Parents and Children, generating data on 1,905 adolescents (mean age 17.8 years, 44.2% boys). LR was measured with the Self-Rating of the Effects of Alcohol Questionnaire, outcomes were based on drinking quantities and problems, and standardized questionnaires were used to evaluate peer substance use, alcohol expectancies, and using alcohol to cope with stress. In this young and large U.K. sample, a low LR related to more adverse alcohol outcomes both directly and through partial mediation by all 3 additional key variables (peer substance use, expectancies, and coping). The models were similar in boys and girls. These results confirm key elements of the hypothesized LR-based model in a large U.K. sample, supporting some generalizability beyond U.S. groups. They also indicate that with enough statistical power, multiple elements contribute to how LR relates to alcohol outcomes and reinforce the applicability of the model to both genders. Copyright © 2011 by the Research Society on Alcoholism.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21424189','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21424189"><span>Short assessment of the Big Five: robust across survey methods except telephone interviewing.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lang, Frieder R; John, Dennis; Lüdtke, Oliver; Schupp, Jürgen; Wagner, Gert G</p> <p>2011-06-01</p> <p>We examined measurement invariance and age-related robustness of a short 15-item Big Five Inventory (BFI-S) of personality dimensions, which is well suited for applications in large-scale multidisciplinary surveys. The BFI-S was assessed in three different interviewing conditions: computer-assisted or paper-assisted face-to-face interviewing, computer-assisted telephone interviewing, and a self-administered questionnaire. Randomized probability samples from a large-scale German panel survey and a related probability telephone study were used in order to test method effects on self-report measures of personality characteristics across early, middle, and late adulthood. Exploratory structural equation modeling was used in order to test for measurement invariance of the five-factor model of personality trait domains across different assessment methods. For the short inventory, findings suggest strong robustness of self-report measures of personality dimensions among young and middle-aged adults. In old age, telephone interviewing was associated with greater distortions in reliable personality assessment. It is concluded that the greater mental workload of telephone interviewing limits the reliability of self-report personality assessment. Face-to-face surveys and self-administrated questionnaire completion are clearly better suited than phone surveys when personality traits in age-heterogeneous samples are assessed.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li class="active"><span>17</span></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_17 --> <div id="page_18" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li class="active"><span>18</span></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="341"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22490518','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22490518"><span>Cost-effectiveness of one versus two sample faecal immunochemical testing for colorectal cancer screening.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Goede, S Lucas; van Roon, Aafke H C; Reijerink, Jacqueline C I Y; van Vuuren, Anneke J; Lansdorp-Vogelaar, Iris; Habbema, J Dik F; Kuipers, Ernst J; van Leerdam, Monique E; van Ballegooijen, Marjolein</p> <p>2013-05-01</p> <p>The sensitivity and specificity of a single faecal immunochemical test (FIT) are limited. The performance of FIT screening can be improved by increasing the screening frequency or by providing more than one sample in each screening round. This study aimed to evaluate if two-sample FIT screening is cost-effective compared with one-sample FIT. The MISCAN-colon microsimulation model was used to estimate costs and benefits of strategies with either one or two-sample FIT screening. The FIT cut-off level varied between 50 and 200 ng haemoglobin/ml, and the screening schedule was varied with respect to age range and interval. In addition, different definitions for positivity of the two-sample FIT were considered: at least one positive sample, two positive samples, or the mean of both samples being positive. Within an exemplary screening strategy, biennial FIT from the age of 55-75 years, one-sample FIT provided 76.0-97.0 life-years gained (LYG) per 1000 individuals, at a cost of € 259,000-264,000 (range reflects different FIT cut-off levels). Two-sample FIT screening with at least one sample being positive provided 7.3-12.4 additional LYG compared with one-sample FIT at an extra cost of € 50,000-59,000. However, when all screening intervals and age ranges were considered, intensifying screening with one-sample FIT provided equal or more LYG at lower costs compared with two-sample FIT. If attendance to screening does not differ between strategies it is recommended to increase the number of screening rounds with one-sample FIT screening, before considering increasing the number of FIT samples provided per screening round.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27418131','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27418131"><span>Panels of tumor-derived RNA markers in peripheral blood of patients with non-small cell lung cancer: their dependence on age, gender and clinical stages.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Chian, Chih-Feng; Hwang, Yi-Ting; Terng, Harn-Jing; Lee, Shih-Chun; Chao, Tsui-Yi; Chang, Hung; Ho, Ching-Liang; Wu, Yi-Ying; Perng, Wann-Cherng</p> <p>2016-08-02</p> <p>Peripheral blood mononuclear cell (PBMC)-derived gene signatures were investigated for their potential use in the early detection of non-small cell lung cancer (NSCLC). In our study, 187 patients with NSCLC and 310 age- and gender-matched controls, and an independent set containing 29 patients for validation were included. Eight significant NSCLC-associated genes were identified, including DUSP6, EIF2S3, GRB2, MDM2, NF1, POLDIP2, RNF4, and WEE1. The logistic model containing these significant markers was able to distinguish subjects with NSCLC from controls with an excellent performance, 80.7% sensitivity, 90.6% specificity, and an area under the receiver operating characteristic curve (AUC) of 0.924. Repeated random sub-sampling for 100 times was used to validate the performance of classification training models with an average AUC of 0.92. Additional cross-validation using the independent set resulted in the sensitivity 75.86%. Furthermore, six age/gender-dependent genes: CPEB4, EIF2S3, GRB2, MCM4, RNF4, and STAT2 were identified using age and gender stratification approach. STAT2 and WEE1 were explored as stage-dependent using stage-stratified subpopulation. We conclude that these logistic models using different signatures for total and stratified samples are potential complementary tools for assessing the risk of NSCLC.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27650175','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27650175"><span>Evaluating the Impact of Genomic Data and Priors on Bayesian Estimates of the Angiosperm Evolutionary Timescale.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Foster, Charles S P; Sauquet, Hervê; van der Merwe, Marlien; McPherson, Hannah; Rossetto, Maurizio; Ho, Simon Y W</p> <p>2017-05-01</p> <p>The evolutionary timescale of angiosperms has long been a key question in biology. Molecular estimates of this timescale have shown considerable variation, being influenced by differences in taxon sampling, gene sampling, fossil calibrations, evolutionary models, and choices of priors. Here, we analyze a data set comprising 76 protein-coding genes from the chloroplast genomes of 195 taxa spanning 86 families, including novel genome sequences for 11 taxa, to evaluate the impact of models, priors, and gene sampling on Bayesian estimates of the angiosperm evolutionary timescale. Using a Bayesian relaxed molecular-clock method, with a core set of 35 minimum and two maximum fossil constraints, we estimated that crown angiosperms arose 221 (251-192) Ma during the Triassic. Based on a range of additional sensitivity and subsampling analyses, we found that our date estimates were generally robust to large changes in the parameters of the birth-death tree prior and of the model of rate variation across branches. We found an exception to this when we implemented fossil calibrations in the form of highly informative gamma priors rather than as uniform priors on node ages. Under all other calibration schemes, including trials of seven maximum age constraints, we consistently found that the earliest divergences of angiosperm clades substantially predate the oldest fossils that can be assigned unequivocally to their crown group. Overall, our results and experiments with genome-scale data suggest that reliable estimates of the angiosperm crown age will require increased taxon sampling, significant methodological changes, and new information from the fossil record. [Angiospermae, chloroplast, genome, molecular dating, Triassic.]. © The Author(s) 2016. Published by Oxford University Press, on behalf of the Society of Systematic Biologists. All rights reserved. For Permissions, please email: journals.permissions@oup.com.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://www.sciencedirect.com/science/article/pii/S0304380014003044','USGSPUBS'); return false;" href="http://www.sciencedirect.com/science/article/pii/S0304380014003044"><span>Population age and initial density in a patchy environment affect the occurrence of abrupt transitions in a birth-and-death model of Taylor's law</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Jiang, Jiang; DeAngelis, Donald L.; Zhang, B.; Cohen, J.E.</p> <p>2014-01-01</p> <p>Taylor's power law describes an empirical relationship between the mean and variance of population densities in field data, in which the variance varies as a power, b, of the mean. Most studies report values of b varying between 1 and 2. However, Cohen (2014a) showed recently that smooth changes in environmental conditions in a model can lead to an abrupt, infinite change in b. To understand what factors can influence the occurrence of an abrupt change in b, we used both mathematical analysis and Monte Carlo samples from a model in which populations of the same species settled on patches, and each population followed independently a stochastic linear birth-and-death process. We investigated how the power relationship responds to a smooth change of population growth rate, under different sampling strategies, initial population density, and population age. We showed analytically that, if the initial populations differ only in density, and samples are taken from all patches after the same time period following a major invasion event, Taylor's law holds with exponent b=1, regardless of the population growth rate. If samples are taken at different times from patches that have the same initial population densities, we calculate an abrupt shift of b, as predicted by Cohen (2014a). The loss of linearity between log variance and log mean is a leading indicator of the abrupt shift. If both initial population densities and population ages vary among patches, estimates of b lie between 1 and 2, as in most empirical studies. But the value of b declines to ~1 as the system approaches a critical point. Our results can inform empirical studies that might be designed to demonstrate an abrupt shift in Taylor's law.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5977132','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5977132"><span>Maternal Educational Attainment at Birth Promotes Future Self-Rated Health of White but Not Black Youth: A 15-Year Cohort of a National Sample</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Caldwell, Cleopatra Howard; Mincy, Ronald B.</p> <p>2018-01-01</p> <p>Background: Socioeconomic status (SES) is essential for maintaining health, and self-rated health (SRH) is not an exception to this rule. This study explored racial differences in the protective effects of maternal educational attainment at birth against poor SRH of the youth 15 years later. Methods: Using data from the Fragile Families and Child Wellbeing Study (FFCWS), this 15-year longitudinal study followed 1934 youths from birth to age 15. This sample was composed of White (n = 497, 25.7%), and Black (n = 1437, 74.3%) youths. The independent variable was maternal educational attainment at birth. SRH at age 15 was the dependent variable. Family structure was the covariate. Race was the focal moderator. We ran logistic regression models in the pooled sample, as well as stratified models based on race. Results: In the pooled sample, maternal educational attainment and family structure were not predictive of SRH for the youths at age 15. Race interacted with maternal educational attainment, indicating a stronger association between maternal educational attainment at birth on youth SRH for Whites compared to Blacks. In race stratified models, maternal educational attainment at birth was protective against poor SRH for White but not Black youths. Conclusion: White but not Black youths gain less SRH from their maternal educational attainment. Enhancing education attainment may not have identical effects across racial groups. The health status of Blacks may be less responsive to improvements in maternal educational attainment. Policies should go beyond investing in educational attainment by empowering Black families to better use the educational attainment that they gain. Policies and programs should reduce the costs of upward social mobility for minority families. PMID:29723957</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29723957','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29723957"><span>Maternal Educational Attainment at Birth Promotes Future Self-Rated Health of White but Not Black Youth: A 15-Year Cohort of a National Sample.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Assari, Shervin; Caldwell, Cleopatra Howard; Mincy, Ronald B</p> <p>2018-05-01</p> <p>Socioeconomic status (SES) is essential for maintaining health, and self-rated health (SRH) is not an exception to this rule. This study explored racial differences in the protective effects of maternal educational attainment at birth against poor SRH of the youth 15 years later. Using data from the Fragile Families and Child Wellbeing Study (FFCWS), this 15-year longitudinal study followed 1934 youths from birth to age 15. This sample was composed of White ( n = 497, 25.7%), and Black ( n = 1437, 74.3%) youths. The independent variable was maternal educational attainment at birth. SRH at age 15 was the dependent variable. Family structure was the covariate. Race was the focal moderator. We ran logistic regression models in the pooled sample, as well as stratified models based on race. In the pooled sample, maternal educational attainment and family structure were not predictive of SRH for the youths at age 15. Race interacted with maternal educational attainment, indicating a stronger association between maternal educational attainment at birth on youth SRH for Whites compared to Blacks. In race stratified models, maternal educational attainment at birth was protective against poor SRH for White but not Black youths. White but not Black youths gain less SRH from their maternal educational attainment. Enhancing education attainment may not have identical effects across racial groups. The health status of Blacks may be less responsive to improvements in maternal educational attainment. Policies should go beyond investing in educational attainment by empowering Black families to better use the educational attainment that they gain. Policies and programs should reduce the costs of upward social mobility for minority families.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3863880','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3863880"><span>A General Model of Dioxin Contamination in Breast Milk: Results from a Study on 94 Women from the Caserta and Naples Areas in Italy</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Rivezzi, Gaetano; Piscitelli, Prisco; Scortichini, Giampiero; Giovannini, Armando; Diletti, Gianfranco; Migliorati, Giacomo; Ceci, Roberta; Rivezzi, Giulia; Cirasino, Lorenzo; Carideo, Pietro; Black, Dennis M.; Garzillo, Carmine; Giani, Umberto</p> <p>2013-01-01</p> <p>Background: The Caserta and Naples areas in Campania Region experience heavy environmental contamination due to illegal waste disposal and burns, thus representing a valuable setting to develop a general model of human contamination with dioxins (PCDDs-PCDFs) and dioxin-like-PCBs (dl-PCBs). Methods: 94 breastfeeding women (aged 19–32 years; mean age 27.9 ± 3.0) were recruited to determine concentrations of PCDDs-PCDFs and dl-PCBs in their milk. Individual milk samples were collected and analyzed according to standard international procedures. A generalized linear model was used to test potential predictors of pollutant concentration in breast milk: age, exposure to waste fires, cigarette smoking, diet, and residence in high/low risk area (defined at high/low environmental pressure by a specific 2007 WHO report). A Structural Equation Model (SEM) analysis was carried out by taking into account PCDDs-PCDFs and dl-PCBs as endogenous variables and age, waste fires, risk area and smoking as exogenous variables. Results: All milk samples were contaminated by PCDDs-PCDFs (8.6 pg WHO-TEQ/98g fat ± 2.7; range 3.8–19) and dl-PCBs (8.0 pg WHO-TEQ/98g fat ± 3.7; range 2.5–24), with their concentrations being associated with age and exposure to waste fires (p < 0.01). Exposure to fires resulted in larger increases of dioxins concentrations in people living in low risk areas than those from high risk areas (p < 0.01). Conclusions: A diffuse human exposure to persistent organic pollutants was observed in the Caserta and Naples areas. Dioxins concentration in women living in areas classified at low environmental pressure in 2007 WHO report was significantly influenced by exposure to burns. PMID:24217180</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4182562','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4182562"><span>Testosterone Trajectories and Reference Ranges in a Large Longitudinal Sample of Male Adolescents</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Khairullah, Ammar; Cousino Klein, Laura; Ingle, Suzanne M.; May, Margaret T.; Whetzel, Courtney A.; Susman, Elizabeth J.; Paus, Tomáš</p> <p>2014-01-01</p> <p>Purpose Pubertal dynamics plays an important role in physical and psychological development of children and adolescents. We aim to provide reference ranges of plasma testosterone in a large longitudinal sample. Furthermore, we describe a measure of testosterone trajectories during adolescence that can be used in future investigations of development. Methods We carried out longitudinal measurements of plasma testosterone in 2,216 samples obtained from 513 males (9 to 17 years of age) from the Avon Longitudinal Study of Parents and Children. We used integration of a model fitted to each participant’s testosterone trajectory to calculate a measure of average exposure to testosterone over adolescence. We pooled these data with corresponding values reported in the literature to provide a reference range of testosterone levels in males between the ages of 6 and 19 years. Results The average values of total testosterone in the ALSPAC sample range from 0.82 nmol/L (Standard Deviation [SD]: 0.09) at 9 years of age to 16.5 (SD: 2.65) nmol/L at 17 years of age; these values are congruent with other reports in the literature. The average exposure to testosterone is associated with different features of testosterone trajectories such as Peak Testosterone Change, Age at Peak Testosterone Change, and Testosterone at 17 years of age as well as the timing of the growth spurt during puberty. Conclusions The average exposure to testosterone is a useful measure for future investigations using testosterone trajectories to examine pubertal dynamics. PMID:25268961</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26458079','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26458079"><span>The social class gradient in health in Spain and the health status of the Spanish Roma.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>La Parra Casado, Daniel; Gil González, Diana; de la Torre Esteve, María</p> <p>2016-10-01</p> <p>To determine the social class gradient in health in general Spain population and the health status of the Spanish Roma. The National Health Survey of Spanish Roma 2006 (sample size = 993 people; average age: 33.6 years; 53.1% women) and the National Health Surveys for Spain 2003 (sample size: 21,650 people; average age: 45.5 years; 51.2% women) and 2006 (sample size: 29,478 people; average age: 46 years; 50.7% women) are compared. Several indicators were chosen: self-perceived health, activity limitation, chronic diseases, hearing and sight problems, caries, and obesity. Analysis was based on age-standardised rates and logistic regression models. According to most indicators, Roma's health is worse than that of social class IV-V (manual workers). Some indicators show a remarkable difference between Roma and social class IV-V: experiencing three or more health problems, sight problems, and caries, in both sexes, and hearing problems and obesity, in women. Roma people are placed on an extreme position on the social gradient in health, a situation of extreme health inequality.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017MNRAS.466.2888H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017MNRAS.466.2888H"><span>Spectral ageing in the era of big data: integrated versus resolved models</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Harwood, Jeremy J.</p> <p>2017-04-01</p> <p>Continuous injection models of spectral ageing have long been used to determine the age of radio galaxies from their integrated spectrum; however, many questions about their reliability remain unanswered. With various large area surveys imminent (e.g. LOw Frequency ARray, MeerKAT, Murchison Widefield Array) and planning for the next generation of radio interferometers are well underway (e.g. next generation VLA, Square Kilometre Array), investigations of radio galaxy physics are set to shift away from studies of individual sources to the population as a whole. Determining if and how integrated models of spectral ageing can be applied in the era of big data is therefore crucial. In this paper, I compare classical integrated models of spectral ageing to recent well-resolved studies that use modern analysis techniques on small spatial scales to determine their robustness and validity as a source selection method. I find that integrated models are unable to recover key parameters and, even when known a priori, provide a poor, frequency-dependent description of a source's spectrum. I show a disparity of up to a factor of 6 in age between the integrated and resolved methods but suggest, even with these inconsistencies, such models still provide a potential method of candidate selection in the search for remnant radio galaxies and in providing a cleaner selection of high redshift radio galaxies in z - α selected samples.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015EGUGA..17.9218H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015EGUGA..17.9218H"><span>How Old is Cone Crater at the Apollo 14 Landing Site?</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Hiesinger, Harald; Simon, Ina; van der Bogert, Carolyn H.; Robinson, Mark S.; Plescia, Jeff B.</p> <p>2015-04-01</p> <p>The Lunar Reconnaissance Orbiter (LRO) Narrow Angle Cameras (NAC) provides new opportunities to investigate crater size-frequency distributions (CSFDs) on individual geological units at key lunar impact craters. We performed new CSFD measurements for the Copernican-aged Cone crater at the Apollo 14 landing site because it is an anchor point for the lunar cratering chronology at young ages [1-4]. Cone crater (340 m diameter) is located about 1100 m NE of the Apollo 14 landing site on a 90 m high ridge of the Fra Mauro Formation, and exhibits a sharp rim [e.g., 5,6,7]. Samples from Cone crater were collected from four stations (Dg, C1, C2, C') during the Apollo 14 mission [7]. Exposure ages of those samples were used to date the formation of Cone crater. Although there is a considerable range of exposure ages (~12 Ma [8] to ~661 Ma [9]), several studies of Cone crater samples indicate an age of ~25-26 Ma [e.g., 2,10,11]. On the basis of our CSFD measurements we determined an absolute model age (AMA) for Cone crater of ~39 Ma, which is in the range of model ages derived by previous CSFD measurements that vary between ~24 Ma [12] and ~73 Ma [13]. However, we found a wide spread of model ages ranging from ~16 to ~82 Ma for individual areas on the crater ejecta blanket. Like [13], we find that the CSFD measurements on LROC images yield older AMAs than previous CSFDs [e.g., 12]. However, our results are closer to the older CSFDs than to those of [13] and are just within the error bars of [14]. Our derived N(1) = 3.26 x 10-5 km-2 is almost identical to the N(1) = 3.36 x 10-5 km-2 of [15]. Comparing the CSFD results to exposure ages of the returned samples we find somewhat older ages. However, at least two of our count areas produce AMAs that are within the error bars of the exposure ages [e.g., 10]. Six other areas show ages that are within two standard deviations to the exposure ages [e.g., 10]. For two count areas that were directly sampled, we obtained ages that are 10 and 23 Ma older than the exposure ages [e.g., 10]. We find that CSFD measurements performed on the ejecta blanket of Cone crater yield AMAs that agree well with the exposure ages, considering the relatively small count areas and the hummocky nature of the ejecta blanket. However, the AMAs are generally older than the exposure ages, which may be due to the small count area sizes [16], a possibly higher recent impact rate [17], some unidentified secondary craters [13], poor calibration of the production function, or inaccurate exposure ages. [1] Hiesinger et al. (2012) J. Geophys. Res. 117. [2] Stöffler and Ryder (2001) Chronology and Evolution of Mars. [3] Neukum (1983) Habil. thesis, U. of Munich. [4] Neukum et al. (2001) Space Sci. Rev. 96. [5] Swann et al. (1971) Apollo 14 Prelim. Sci. Rep. [6] Carlson (1978) NASA STI/Recon Technical Report. [7] Swann (1977) Washington US Govt. Print. Off. [8] Bhandari et al. (1972) Proc. Lunar Planet. Sci. Conf. 3. [9] Crozaz et al. (1972) Proc. Lunar Planet. Sci. Conf. 3. [10] Arvidson et al. (1975) Moon 13. [11] Stadermann et al. (1991) Geochim. Cosmochim. Acta 55. [12] Moore et al. (1980) Moon and Planets 23. [13] Plescia and Robinson (2011) LPSC 42. [14] Williams et al. (2014) Icarus 235. [15] Robbins (2014) Earth Planet. Sci. Lett. 403. [16] van der Bogert et al. (2015) LPSC 46. [17] McEwen et al. (2015) LPSC 46.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3254821','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3254821"><span>Dynamic Bayesian network modeling for longitudinal brain morphometry</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Chen, Rong; Resnick, Susan M; Davatzikos, Christos; Herskovits, Edward H</p> <p>2011-01-01</p> <p>Identifying interactions among brain regions from structural magnetic-resonance images presents one of the major challenges in computational neuroanatomy. We propose a Bayesian data-mining approach to the detection of longitudinal morphological changes in the human brain. Our method uses a dynamic Bayesian network to represent evolving inter-regional dependencies. The major advantage of dynamic Bayesian network modeling is that it can represent complicated interactions among temporal processes. We validated our approach by analyzing a simulated atrophy study, and found that this approach requires only a small number of samples to detect the ground-truth temporal model. We further applied dynamic Bayesian network modeling to a longitudinal study of normal aging and mild cognitive impairment — the Baltimore Longitudinal Study of Aging. We found that interactions among regional volume-change rates for the mild cognitive impairment group are different from those for the normal-aging group. PMID:21963916</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1395530-accretion-timescale-impact-history-mars-deduced-from-isotopic-systematics-martian-meteorites','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1395530-accretion-timescale-impact-history-mars-deduced-from-isotopic-systematics-martian-meteorites"><span>Accretion timescale and impact history of Mars deduced from the isotopic systematics of martian meteorites</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a></p> <p>Borg, Lars E.; Brennecka, Gregory A.; Symes, Steven J. K.</p> <p>2015-12-12</p> <p>High precision Sm-Nd isotopic analyses have been completed on a suite of 11 martian basaltic meteorites in order to better constrain the age of silicate differentiation on Mars associated with the formation of their mantle sources. Our data is used to evaluate the merits and disadvantages of various mathematical approaches that have been employed in previous work on this topic. Ages determined from the Sm-Nd isotopic systematics of individual samples are strongly dependent on the assumed Nd isotopic composition of the bulk planet. This assumption is problematic given differences observed between the Nd isotopic composition of Earth and chondritic meteoritesmore » and the fact that these materials are both commonly used to represent bulk planetary Nd isotopic compositions. Ages determined from the slope of Sm-146-Nd-142 whole rock isochrons are not dependent on the assumed Nd-142/Nd-144 ratio of the planet, but require the sample suite to be derived from complementary, contemporaneously-formed reservoirs. In this work, we present a mathematical expression that defines the age of formation of the source regions of such a suite of samples that is based solely on the slope of a Nd-143-Nd-142 whole rock isochron and is also independent of any a priori assumptions regarding the bulk isotopic composition of the planet. This expression is also applicable to mineral isochrons and has been used to successfully calculate Nd-143-Nd-142 model crystallization ages of early refractory solids as well as lunar samples. This permits ages to be obtained using only Nd isotopic measurements without the need for Sm-147/Nd-144 isotope dilution determinations. When used in conjunction with high-precision Nd isotopic measurements completed on martian meteorites this expression yields an age of formation of the martian basaltic meteorite source regions of 4504 +/- 6 Ma. Because the Sm-Nd model ages for the formation of martian source regions are commonly interpreted to record the age at which large scale mantle reservoirs formed during planetary differentiation associated with magma ocean solidification, the age determined here implies that magma ocean solidification occurred several tens of millions of years after the beginning of the Solar System. Recent thermal models, however, suggest that Mars-sized bodies cool rapidly in less than similar to 5 Ma after accretion ceases, even in the presence of a thick atmosphere. In assuming these models are correct, an extended period of accretion is necessary to provide a mechanism to keep portions of the martian mantle partially molten until 4504 Ma. Late accretional heating of Mars could either be associated with protracted accretion occurring at a quasi-steady state or alternatively be associated with a late giant impact. If this scenario is correct, then accretion of Mars-sized bodies takes up to 60 Ma and is likely to be contemporaneous with the core formation and possibly the onset of silicate differentiation. This further challenges the concept that isotopic equilibrium is attained during primordial evolution of planets, and may help to account for geochemical evidence implying addition of material into planetary interiors after core formation was completed.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/1395530','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/1395530"><span>Accretion timescale and impact history of Mars deduced from the isotopic systematics of martian meteorites</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Borg, Lars E.; Brennecka, Gregory A.; Symes, Steven J. K.</p> <p></p> <p>High precision Sm-Nd isotopic analyses have been completed on a suite of 11 martian basaltic meteorites in order to better constrain the age of silicate differentiation on Mars associated with the formation of their mantle sources. Our data is used to evaluate the merits and disadvantages of various mathematical approaches that have been employed in previous work on this topic. Ages determined from the Sm-Nd isotopic systematics of individual samples are strongly dependent on the assumed Nd isotopic composition of the bulk planet. This assumption is problematic given differences observed between the Nd isotopic composition of Earth and chondritic meteoritesmore » and the fact that these materials are both commonly used to represent bulk planetary Nd isotopic compositions. Ages determined from the slope of Sm-146-Nd-142 whole rock isochrons are not dependent on the assumed Nd-142/Nd-144 ratio of the planet, but require the sample suite to be derived from complementary, contemporaneously-formed reservoirs. In this work, we present a mathematical expression that defines the age of formation of the source regions of such a suite of samples that is based solely on the slope of a Nd-143-Nd-142 whole rock isochron and is also independent of any a priori assumptions regarding the bulk isotopic composition of the planet. This expression is also applicable to mineral isochrons and has been used to successfully calculate Nd-143-Nd-142 model crystallization ages of early refractory solids as well as lunar samples. This permits ages to be obtained using only Nd isotopic measurements without the need for Sm-147/Nd-144 isotope dilution determinations. When used in conjunction with high-precision Nd isotopic measurements completed on martian meteorites this expression yields an age of formation of the martian basaltic meteorite source regions of 4504 +/- 6 Ma. Because the Sm-Nd model ages for the formation of martian source regions are commonly interpreted to record the age at which large scale mantle reservoirs formed during planetary differentiation associated with magma ocean solidification, the age determined here implies that magma ocean solidification occurred several tens of millions of years after the beginning of the Solar System. Recent thermal models, however, suggest that Mars-sized bodies cool rapidly in less than similar to 5 Ma after accretion ceases, even in the presence of a thick atmosphere. In assuming these models are correct, an extended period of accretion is necessary to provide a mechanism to keep portions of the martian mantle partially molten until 4504 Ma. Late accretional heating of Mars could either be associated with protracted accretion occurring at a quasi-steady state or alternatively be associated with a late giant impact. If this scenario is correct, then accretion of Mars-sized bodies takes up to 60 Ma and is likely to be contemporaneous with the core formation and possibly the onset of silicate differentiation. This further challenges the concept that isotopic equilibrium is attained during primordial evolution of planets, and may help to account for geochemical evidence implying addition of material into planetary interiors after core formation was completed.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20040175643&hterms=women&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D50%26Ntt%3Dwomen','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20040175643&hterms=women&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D50%26Ntt%3Dwomen"><span>Changes in aerobic power of women, ages 20-64 yr</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Jackson, A. S.; Wier, L. T.; Ayers, G. W.; Beard, E. F.; Stuteville, J. E.; Blair, S. N.</p> <p>1996-01-01</p> <p>This study quantified and compared the cross-sectional and longitudinal influence of age, self-report physical activity (SR-PA), and body composition (%fat) on the decline of maximal aerobic power (VO2peak) of women. The cross-sectional sample consisted of 409 healthy women, ages 20-64 yr. The 43 women of the longitudinal sample were from the same population and examined twice, the mean time between tests was 3.7 (+/-2.2) yr. Peak oxygen uptake was determined by indirect calorimetry during a maximal treadmill test. The zero-order correlation of -0.742 between VO2peak and %fat was significantly (P < 0.05) higher then the SR-PA (r = 0.626) and age correlations (r = -0.633). Linear regression defined the cross-sectional age-related decline in VO2peak at 0.537 ml.kg-1.min-1.yr-1. Multiple regression analysis (R = 0.851) showed that adding %fat and SR-PA and their interaction to the regression model reduced the age regression weight of -0.537, to -0.265 ml.kg-1.min-1.yr-1. Statistically controlling for time differences between tests, general linear models analysis showed that longitudinal changes in aerobic power were due to independent changes in %fat and SR-PA, confirming the cross-sectional results. These findings are consistent with men's data from the same lab showing that about 50% of the cross-sectional age-related decline in VO2peak was due to %fat and SR-PA.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22123879','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22123879"><span>Association between weight and risk of crash-related injuries for children in child restraints.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Zonfrillo, Mark R; Elliott, Michael R; Flannagan, Carol A; Durbin, Dennis R</p> <p>2011-12-01</p> <p>To determine the association between weight and the risk of injury in motor vehicle crashes (MVCs) for children 1 through 8 years of age who were using child restraints. This was a cross-sectional study of children 1 to 8 years of age in MVCs, in which cases from the National Automotive Sampling System Crashworthiness Data System were used. Abbreviated Injury Scale scores of ≥2 indicated clinically significant injuries. The National Automotive Sampling System Crashworthiness Data System study sample included 650 children 1 to 5 years of age in forward-facing child restraints who weighed 20 to 65 lb and 344 children 3 to 8 years of age in belt-positioning booster seats who weighed 30 to 100 lb. With adjustment for seating position, type of vehicle, direction of impact, crash severity, and vehicle model year, there was no association between absolute weight and clinically significant injuries in either age group (odds ratio: 1.17 [95% confidence interval: 0.96-1.42] for children 1-5 years of age in forward-facing child restraints and 1.22 [95% confidence interval: 0.96-1.55] for children 3-8 years of age in belt-positioning booster seats). The risk of clinically significant injuries was not associated with weight across a broad weight range in this sample of children in MVCs who were using child restraint systems. Parents should continue to restrain their children according to current recommendations from the American Academy of Pediatrics and the National Highway Traffic Safety Administration.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AGUFM.T43A0664S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AGUFM.T43A0664S"><span>The Exhumation of the Central Lhasa, Tibet: Evidence from the Low-temperature Thermochronology</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sun, G.; Xiumian, H.; Sinclair, H. D.; Stuart, F. M.</p> <p>2017-12-01</p> <p>The modern Tibetan Plateau has an average elevation of 4500 m above the sea level. But its early growth history still remains debate, despite its significance to the global climate system. In common, the early growth of the Tibetan Plateau has been attributed to the India-Asia collision in the early Paleocene. However, the structural reconstruction, Late Cretaceous sedimentation, and petrology studies, imply there would be a paleo-plateau or the high-elevation gain in the Lhasa terrane prior to the India-Asia collision. In order to examine this model, the zircon/apatite U-Th-He (ZHe and AHe) and apatite fission track (AFT) are employed to the mid-Cretaceous granites in Coqen area, central Lhasa. Eight samples from the plateau surface yield ZHe ages ranging from 88 to 54 Ma, while the AHe ages ranging from 70 to 45 Ma. Five samples from the above have been conducted the AFT analysis and yielded AFT ages ranging between 73 and 62 Ma, showing the similar age ranges with the corresponding AHe ages. Single-sample inverse thermal kinetic modeling reveal that these intrusive rocks have undergone the rapid cooling history since 85 Ma, after when, the relatively slow cooling process has been established at 45 Ma. Inverse thermal-kinetic modeling of these data, recorded in the context of the Late Cretaceous rapid cooling history, is best interpreted by the early plateau growth in the central Lhasa. In consideration of the substantial crustal thickening and shortening in the Lhasa terrane during the Cretaceous, this Late Cretaceous-Early Paleogene rapid cooling history reveal that the exhumation of the central Lhasa has initiated before the India-Asia collision. This scenario is consistent with a 30 Ma ( 90-60 Ma) sedimentation hiatus since the Late Cretaceous terrestrial conglomerate deposition in the central Lhasa terrane.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016CorRe..35..641T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016CorRe..35..641T"><span>Revised paleoenvironmental analysis of the Holocene portion of the Barbados sea-level record: Cobbler's Reef revisited</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Toscano, Marguerite A.</p> <p>2016-06-01</p> <p>Sample elevations corrected for tectonic uplift and assessed relative to local modeled sea levels provide a new perspective on paleoenvironmental history at Cobbler's Reef, Barbados. Previously, 14C-dated surface samples of fragmented Acropora palmata plotted above paleo sea level based on their present (uplifted) elevations, suggesting supratidal rubble deposited during a period of extreme storms (4500-3000 cal BP), precipitating reef demise. At several sites, however, A. palmata persisted, existing until ~370 cal BP. Uplift-corrected A. palmata sample elevations lie below the western Atlantic sea-level curve, and ~2 m below ICE-6G-modeled paleo sea level, under slow rates of sea-level rise, negating the possibility that Cobbler's Reef is a supratidal storm ridge. Most sites show limited age ranges from corals likely damaged/killed on the reef crest, not the mixed ages of rubble ridges, strongly suggesting the reef framework died off in stages over 6500 yr. Reef crest death assemblages invoke multiple paleohistoric causes, from ubiquitous hurricanes to anthropogenic impacts. Comparison of death assemblage ages to dated regional paleotempestological sequences, proxy-based paleotemperatures, recorded hurricanes, tsunamis, European settlement, deforestation, and resulting turbidity, reveals many possible factors inimical to the survival of A. palmata along Cobbler's Reef.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.usgs.gov/of/1996/0669/report.pdf','USGSPUBS'); return false;" href="https://pubs.usgs.gov/of/1996/0669/report.pdf"><span>Pliocene planktic foraminifer census data from the North Atlantic region</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>,</p> <p>1996-01-01</p> <p>INTRODUCTION: The U.S. Geological Survey is conducting a long-term study of the climatic and oceanographic conditions of the Pliocene known as PRISM (Pliocene Research, Interpretation, and Synoptic Mapping). One of the major elements of the study involves the use of quantitative composition of planktic foraminifer assemblages to estimate seasurface temperatures and identify major oceanographic boundaries and water masses (Dowsett, 1991; Dowsett and Poore, 1991; Dowsett et al., 1992; Dowsett et al., 1994). We have analyzed more than 900 samples from 19 core sites in the North Atlantic Basin (Fig. 1) resulting in a large volume of raw census data. These data are presented here together to facilitate comparison of North Atlantic faunal assemblages. Latitude, longitude, water depth, source of faunal data and source of data used to construct age model (or publication from which age model was taken) are provided for each locality in Table 1. All ages refer to the geomagnetic polarity time scale of Berggren et al. (1985). Counts of species tabulated in each sample are given in Tables 2-20. DSDP and ODP sample designations are abbreviated in Tables 2-20 as core-section, depth within section in centimeters (eg. 10-5, 34 = core 10, section 5, 34 cm below top of section 5).</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25529556','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25529556"><span>Emergence of norovirus GI.2 outbreaks in military camps in Singapore.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ho, Zheng Jie Marc; Vithia, Gunalan; Ng, Ching Ging; Maurer-Stroh, Sebastian; Tan, Clive M; Loh, Jimmy; Lin, Tzer Pin Raymond; Lee, Jian Ming Vernon</p> <p>2015-02-01</p> <p>Simultaneous acute gastroenteritis (AGE) outbreaks occurred at two military camps. This study details the epidemiological findings, explores possible origins, and discusses preventive measures. Investigations included attack rate surveys, symptom surveys, hygiene inspections, and the testing of water, food, and stool samples. DNA/RNA was extracted from stool samples and amplified via real-time reverse transcription PCR (RT-PCR). Partial and full-length capsid nucleotide sequences were obtained, phylogenetic relationships inferred, and homology modelling of antigenic sites performed. The military outbreaks involved 775 persons and were preceded by two AGE outbreaks at restaurants in the local community. The outbreak was longer and larger in the bigger camp (21 days, attack rate 15.0%) than the smaller camp (6 days, attack rate 8.3%). Of 198 stool samples, norovirus GI.2 was detected in 32.5% (larger camp) and 28.6% (smaller camp). These were essentially identical to preceding community outbreaks. Antigenic site homology modelling also showed differences between identified and more common AGE outbreak strains (norovirus GII.4). Differences observed highlight difficulties in controlling person-to-person outbreaks among large groups in close proximity (e.g., military trainees). Distinct differences in antigenic sites may have contributed to increased immunological susceptibility of the soldiers to infection. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li class="active"><span>18</span></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_18 --> <div id="page_19" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li class="active"><span>19</span></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="361"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28541549','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28541549"><span>Cognitive development in children up to age 11 years born after ART-a longitudinal cohort study.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Barbuscia, Anna; Mills, Melinda C</p> <p>2017-07-01</p> <p>How does the cognitive development of children conceived after ART (IVF and ICSI) - measured as cognitive skills at age 3, 5, 7 and 11 years - differ over time from those born after natural conception (NC)? Improved measures of cognitive development up to age 5 years were recorded in children conceived with ART compared to NC, which attenuates by 11 years, with ART children still scoring slightly better than NC children. Results on the cognitive outcomes of children conceived after ART have been highly contradictory. Some have shown that ART children have an impaired behavioural, socio-emotional and cognitive development and higher risk of mental disorders. Others have reported no increased risk or difference. Cognitive development has not been previously examined using latent growth curve models from ages 3 to 11 years, also including appropriate attention to confounding parental characteristics. Longitudinal data for the first five waves (2000-2012) of the UK Millennium Cohort Study were used, which is a two-stage sample of all infants born in 2000-2001 and resident in the UK at 9 months of age, drawn from the Department of Social Security Child Benefit Registers. A final sample of N = 15 218 children (125 IVF and 61 ICSI), from 14 816 families was used. Information was available for all waves for 8298 children. Four additional follow-up surveys were conducted in 2003, 2005, 2007 and 2012. Our sample includes children born within a union (married or cohabiting parents) and where information on cognitive scores was available for at least two measurement points. Cognitive development was assessed with the British Ability Scales. At age 3 and 5 years (wave 2 and 3), children completed the naming vocabulary component, which measures expressive verbal ability. At age 7 years (wave 4), verbal cognitive abilities were assessed through the word reading test, and at age 11 years (wave 5) through a verbal similarity test. Two-tailed Student's t-tests examined differences between ART and NC groups. Growth curve models (random-coefficient, latent trajectory models) were used to study the effect of ART, confounding parental characteristics and health outcomes at birth, both at a baseline level of cognitive ability at age 3 years and on its growth rate. At age 3 and 5 years, children conceived with the aid of ART have higher verbal cognitive abilities than NC children (P < 0.001) but this consistently decreases over time and diminishes by age 11 years. Parental environment and resources are pivotal in children's cognitive development. The sample size of the ART cohort of children is small across each time period (N = 150-180) in comparison with NC children (N = 10 496-11 955). Owing to a limited sample size, we are also unable to compare IVF versus ICSI treatment. With the increasing use of IVF and ICSI, these results indicate that there are no detrimental effects on children's early cognitive outcomes up to age 11 years, and highlight the importance of parental characteristics. Funding for this project was provided by the European Union's Seventh Framework Program (FP7 2007-2013) (No. 320116 Families and Societies), ESRC/NCRM SOCGEN Grant (ES/N0011856/1) and the SOCIOGENOME ERC Consolidator Grant (ERC-2013-CoG-615603) (to M.C.M.). The authors have no competing interests to declare. N/A. © The Author 2017. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5321170','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5321170"><span>Effect of Trajectories of Friends' and Parents' School Involvement on Adolescents' Engagement and Achievement</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Im, Myung Hee; Hughes, Jan N.; West, Stephen G.</p> <p>2016-01-01</p> <p>In a sample of 527 academically at-risk youth, we investigated trajectories of friends' and parents' school involvement across ages 12–14 and the joint contributions of these trajectories to adolescents' age 15 school engagement and academic achievement. Girls reported higher levels of friends' and parents' school involvement than boys. Both parents' and friends' school involvement declined across ages 12–14. Combined latent growth models and structural equation models showed effects of the trajectories of friends' and parents' school involvement on adolescents' age 15 school engagement and academic achievement, over and above adolescents' prior performance. These effects were additive rather than interactive. Strategies for enhancing parent involvement in school and students' affiliation with peers who are positively engaged in school are discussed. PMID:28239244</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28239244','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28239244"><span>Effect of Trajectories of Friends' and Parents' School Involvement on Adolescents' Engagement and Achievement.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Im, Myung Hee; Hughes, Jan N; West, Stephen G</p> <p>2016-12-01</p> <p>In a sample of 527 academically at-risk youth, we investigated trajectories of friends' and parents' school involvement across ages 12-14 and the joint contributions of these trajectories to adolescents' age 15 school engagement and academic achievement. Girls reported higher levels of friends' and parents' school involvement than boys. Both parents' and friends' school involvement declined across ages 12-14. Combined latent growth models and structural equation models showed effects of the trajectories of friends' and parents' school involvement on adolescents' age 15 school engagement and academic achievement, over and above adolescents' prior performance. These effects were additive rather than interactive. Strategies for enhancing parent involvement in school and students' affiliation with peers who are positively engaged in school are discussed.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26892636','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26892636"><span>Cross-Cultural Validation of the Basic Psychological Needs in Physical Education Scale between Portugal and Brazil Samples.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Cid, Luis; Lettnin, Carla; Stobäus, Claus; Monteiro, Diogo; Davoglio, Tárcia; Moutão, João</p> <p>2016-02-19</p> <p>The main propose of this study is the cross-cultural validation of the Basic Psychological Needs in Physical Education Scale among Portugal and Brazil samples, through the study of measurement model invariance. Participated in this study, two independent samples, one with 616 Portuguese students, of the 2nd and 3rd basic grade of public school, aged between 9 and 18 years old and another with 450 Brazilian students, from 1st, 2nd and 3rd middle grade of public and private school, aged between 14 and 18 years old. The results support the suitability of the model (three factors, each one with four items), showing an adequate fit to the data in each sample (Portugal: χ2 = 203.8, p = .001, df = 51, SRMR = .062, NNFI = .926, CFI = .943, RMSEA = .070, RMSEA 90% IC = .060-.080; Brazil: χ2 = 173.7, p = .001, df = 51, SRMR = .052, NNFI = .940, CFI = .954, RMSEA = .073, RMSEA 90% IC = .061-.085), as well valid cross-cultural invariance among Portuguese e Brazilian samples (∆CFI ≤ .01). Those findings allow us to conclude that scale can be used to measure the basic psychological needs in physical education in Portugal and in Brazil.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25651316','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25651316"><span>Improving sexual health communication between older women and their providers: how the integrative model of behavioral prediction can help.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hughes, Anne K; Rostant, Ola S; Curran, Paul G</p> <p>2014-07-01</p> <p>Talking about sexual health can be a challenge for some older women. This project was initiated to identify key factors that improve communication between aging women and their primary care providers. A sample of women (aged 60+) completed an online survey regarding their intent to communicate with a provider about sexual health. Using the integrative model of behavioral prediction as a guide, the survey instrument captured data on attitudes, perceived norms, self-efficacy, and intent to communicate with a provider about sexual health. Data were analyzed using structural equation modeling. Self-efficacy and perceived norms were the most important factors predicting intent to communicate for this sample of women. Intent did not vary with race, but mean scores of the predictors of intent varied for African American and White women. Results can guide practice and intervention with ethnically diverse older women who may be struggling to communicate about their sexual health concerns. © The Author(s) 2013.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2003IAUJD...5E..27S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2003IAUJD...5E..27S"><span>Age of Local Galactic Disk from the Wdlf for Cpmbs</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Smith, J. Allyn; Oswalt, Terry D.; Wood, Matt A.; Silvestri, Nicole M.</p> <p></p> <p>We present the white dwarf luminosity function (WDLF) for common proper motion systems. This WDLF was derived using the 1/Vmax method pioneered by Schmidt (1975) and detailed by Liebert Dahn and Monet (1988). New cooling models were used to determine the luminosities of the white dwarfs and the age of the local Galactic disk. Comparison to WDLFs developed using older colling models (Wood 1995) will be examined for changes in the derived disk age. Kinematic data is available for a subset of the WDs in the sample. Separate luminosity functions will be examined for each of the statistically significant subsets. JAS acknowledges support from NASA GSRP Fellowship NGT-51086.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/1235436','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/1235436"><span>Status Report - Cane Fiberboard Properties And Degradation Rates For Storage Of The 9975 Shipping Package In KAC</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Daugherty, W.</p> <p></p> <p>Thermal, mechanical and physical properties have been measured on cane fiberboard samples following accelerated aging for up to approximately 10 years. The aging environments have included elevated temperature < 250 ºF (the maximum allowed service temperature for fiberboard in 9975 packages) and elevated humidity. The results from this testing have been analyzed, and aging models fit to the data. Correlations relating several properties (thermal conductivity, energy absorption, weight, dimensions and density) to their rate of change in potential storage environments have been developed. Combined with an estimate of the actual conditions the fiberboard experiences in KAC, these models allow developmentmore » of service life predictions.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=entrepreneurship+AND+intention&pg=3&id=EJ993503','ERIC'); return false;" href="https://eric.ed.gov/?q=entrepreneurship+AND+intention&pg=3&id=EJ993503"><span>Who Becomes an Entrepreneur? Early Life Experiences as Predictors of Entrepreneurship</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Schoon, Ingrid; Duckworth, Kathryn</p> <p>2012-01-01</p> <p>Taking a longitudinal perspective, we tested a developmental-contextual model of entrepreneurship in a nationally representative sample. Following the lives of 6,116 young people in the 1970 British Birth Cohort from birth to age 34, we examined the role of socioeconomic background, parental role models, academic ability, social skills, and…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70197150','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70197150"><span>Paleomagnetism and 40Ar/39Ar ages from volcanics extruded during the Matuyama and Brunhes Chrons near McMurdo Sound, Antarctica</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Tauxe, L.; Gans, Philip B.; Mankinen, Edward A.</p> <p>2004-01-01</p> <p>Maps of virtual geomagnetic poles derived from international geomagnetic reference field models show large lobes with significant departures from the spin axis. These lobes persist in field models for the last few millenia. The anomalous lobes are associated with observation sites at extreme southerly latitudes. To determine whether these features persist for millions of years, paleomagnetic vector data from the continent of Antarctica are essential. We present here new paleomagnetic vector data and 40Ar/39Ar ages from lava flows spanning the Brunhes and Matuyama Chrons from the vicinity of McMurdo Sound, Antarctica. Oriented paleomagnetic samples were collected from 50 lava flows by E. Mankinen and A. Cox in the 1965–1966 austral summer season. Preliminary data based largely on the natural remanent magnetization (NRM) directions were published by Mankinen and Cox [1988]. We have performed detailed paleomagnetic investigations of 37 sites with multiple fully oriented core samples to investigate the reliability of results from this unique sample collection. Of these, only one site fails to meet our acceptance criteria for directional data. Seven sites are reversely magnetized. The mean normal and reverse directions are antipodal. The combined mean direction has = 12, = −86, α = 4, κ = 37 and is indistinguishable from that expected from a GAD field. We obtained reproducible absolute paleointensity estimates from 15 lava flows with a mean dipole moment of 49 ZAm2 and a standard deviation of 28 ZAm2. 40Ar/39Ar age determinations were successfully carried out on samples from 18 of the flows. Our new isotopic ages and paleomagnetic polarities are consistent with the currently accepted geomagnetic reversal timescales.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28512057','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28512057"><span>Normative morphometric data for cerebral cortical areas over the lifetime of the adult human brain.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Potvin, Olivier; Dieumegarde, Louis; Duchesne, Simon</p> <p>2017-08-01</p> <p>Proper normative data of anatomical measurements of cortical regions, allowing to quantify brain abnormalities, are lacking. We developed norms for regional cortical surface areas, thicknesses, and volumes based on cross-sectional MRI scans from 2713 healthy individuals aged 18 to 94 years using 23 samples provided by 21 independent research groups. The segmentation was conducted using FreeSurfer, a widely used and freely available automated segmentation software. Models predicting regional cortical estimates of each hemisphere were produced using age, sex, estimated total intracranial volume (eTIV), scanner manufacturer, magnetic field strength, and interactions as predictors. The explained variance for the left/right cortex was 76%/76% for surface area, 43%/42% for thickness, and 80%/80% for volume. The mean explained variance for all regions was 41% for surface areas, 27% for thicknesses, and 46% for volumes. Age, sex and eTIV predicted most of the explained variance for surface areas and volumes while age was the main predictors for thicknesses. Scanner characteristics generally predicted a limited amount of variance, but this effect was stronger for thicknesses than surface areas and volumes. For new individuals, estimates of their expected surface area, thickness and volume based on their characteristics and the scanner characteristics can be obtained using the derived formulas, as well as Z score effect sizes denoting the extent of the deviation from the normative sample. Models predicting normative values were validated in independent samples of healthy adults, showing satisfactory validation R 2 . Deviations from the normative sample were measured in individuals with mild Alzheimer's disease and schizophrenia and expected patterns of deviations were observed. Crown Copyright © 2017. Published by Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28952046','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28952046"><span>Moderators of the Relations Between Mothers' and Fathers' Parenting Practices and Children's Prosocial Behavior.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Gryczkowski, Michelle; Jordan, Sara Sytsma; Mercer, Sterett H</p> <p>2018-06-01</p> <p>Using multilevel modeling, we separately examined the relations between mothers' and fathers' parenting practices and children's prosocial behavior, as well as the moderating roles of child sex, age, and ethnicity. Participants included a diverse community sample of 129 cohabiting couples with a child aged 6-17. Results indicated that paternal positivity and corporal punishment were significantly related to girls', but not boys', prosocial behavior, and paternal involvement was related to prosocial behavior in school-aged children but not adolescents. Greater levels of positivity in both parents were related to more prosocial behavior in Caucasian children and less in African American children. Overall, the findings suggest that fathers' parenting is important and may differentially influence children of different sexes and ages, underscoring the importance of examining both mothers' and fathers' parenting in relation to child outcomes and with diverse samples. Findings also highlight the need for culturally appropriate measures of parenting.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25585020','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25585020"><span>Quantile rank maps: a new tool for understanding individual brain development.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Chen, Huaihou; Kelly, Clare; Castellanos, F Xavier; He, Ye; Zuo, Xi-Nian; Reiss, Philip T</p> <p>2015-05-01</p> <p>We propose a novel method for neurodevelopmental brain mapping that displays how an individual's values for a quantity of interest compare with age-specific norms. By estimating smoothly age-varying distributions at a set of brain regions of interest, we derive age-dependent region-wise quantile ranks for a given individual, which can be presented in the form of a brain map. Such quantile rank maps could potentially be used for clinical screening. Bootstrap-based confidence intervals are proposed for the quantile rank estimates. We also propose a recalibrated Kolmogorov-Smirnov test for detecting group differences in the age-varying distribution. This test is shown to be more robust to model misspecification than a linear regression-based test. The proposed methods are applied to brain imaging data from the Nathan Kline Institute Rockland Sample and from the Autism Brain Imaging Data Exchange (ABIDE) sample. Copyright © 2015 Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2848299','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2848299"><span>Workplace Determinants of Endotoxin Exposure in Dental Healthcare Facilities in South Africa</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Singh, Tanusha S.; Bello, Braimoh; Mabe, Onnicah D.; Renton, Kevin; Jeebhay, Mohamed F.</p> <p>2010-01-01</p> <p>Objectives: Aerosols generated during dental procedures have been reported to contain endotoxin as a result of bacterial contamination of dental unit water lines. This study investigated the determinants of airborne endotoxin exposure in dental healthcare settings. Methods: The study population included dental personnel (n = 454) from five academic dental institutions in South Africa. Personal air samples (n = 413) in various dental jobs and water samples (n = 403) from dental handpieces and basin taps were collected. The chromogenic-1000 limulus amebocyte lysate assay was used to determine endotoxin levels. Exposure metrics were developed on the basis of individually measured exposures and average levels within each job category. Analysis of variance and multivariate linear regression models were constructed to ascertain the determinants of exposure in the dental group. Results: There was a 2-fold variation in personal airborne endotoxin from the least exposed (administration) to the most exposed (laboratory) jobs (geometric mean levels: 2.38 versus 5.63 EU m−3). Three percent of personal samples were above DECOS recommended exposure limit (50 EU m−3). In the univariate linear models, the age of the dental units explained the most variability observed in the personal air samples (R2 = 0.20, P < 0.001), followed by the season of the year (R2 = 0.11, P < 0.001). Other variables such as institution and total number of dental units per institution also explained a modest degree of variability. A multivariate model explaining the greatest variability (adjusted R2 = 0.40, P < 0.001) included: the age of institution buildings, total number of dental units per institution, ambient temperature, ambient air velocity, endotoxin levels in water, job category (staff versus students), dental unit model type and age of dental unit. Conclusions: Apart from job type, dental unit characteristics are important predictors of airborne endotoxin levels in this setting. PMID:20044586</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=contraceptive&pg=5&id=EJ873799','ERIC'); return false;" href="https://eric.ed.gov/?q=contraceptive&pg=5&id=EJ873799"><span>Parental Support and Knowledge and Adolescents' Sexual Health: Testing Two Mediational Models in a National Dutch Sample</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>de Graaf, Hanneke; Vanwesenbeeck, Ine; Woertman, Liesbeth; Keijsers, Loes; Meijer, Suzanne; Meeus, Wim</p> <p>2010-01-01</p> <p>This study investigated age- and gender-specific associations between parental support and parental knowledge of the child's whereabouts, on the one hand, and sexual experience and sexual health (the ability to have safe and pleasurable sexual experiences) on the other hand. A representative Dutch sample of 1,263 males and 1,353 females (aged…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=Standardization+AND+processes&pg=5&id=EJ793358','ERIC'); return false;" href="https://eric.ed.gov/?q=Standardization+AND+processes&pg=5&id=EJ793358"><span>A Confirmatory Factor Analysis of the California Verbal Learning Test-Second Edition (CVLT-II) in the Standardization Sample</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Donders, Jacobus</p> <p>2008-01-01</p> <p>The purpose of this study is to determine the latent structure of the California Verbal Learning Test-Second Edition (CVLT-II; Delis, Kramer, Kaplan, & Ober, 2000) at three different age levels, using the standardization sample. Maximum likelihood confirmatory factor analyses are performed to test four competing hypothetical models for fit and…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28560895','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28560895"><span>Age Diversity in the Workplace.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Yang, Jie; Matz-Costa, Christina</p> <p>2017-01-01</p> <p>Although having a younger supervisor or a supervisor of a similar age runs counter to the traditional older supervisor-younger subordinate norm, it is becoming increasingly common in the 21st-century workplace. The current study uses theories of relational demography and relational norms as well as Selective Optimization with Compensation theory and the job demands-resources model to understand how relational age within supervisor-employee dyads influences workers' engagement. Cross-sectional data from a multiworksite (U.S.-based) sample of 2,195 workers aged 18 to 81 years were used to estimate ordinary least squares regression models. After accounting for a variety of factors that could influence engagement levels (i.e., demographics, health status, and job or personal resources), findings indicated that employees with similar-age supervisors were less engaged than employees with older supervisors. Moreover, while employees who did not know the ages of their supervisors were just as engaged as employees with older supervisors. Implications for engaging an age-diverse workforce are discussed.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018DSRII.147...98L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018DSRII.147...98L"><span>Distribution of juvenile Pacific herring relative to environmental and geospatial factors in Prince William Sound, Alaska</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Lewandoski, Sean; Bishop, Mary Anne</p> <p>2018-01-01</p> <p>Documenting distribution patterns of juvenile Pacific herring (Clupea pallasii) can clarify habitat preferences and provide insight into ecological factors influencing early life survival. However, few analyses relating juvenile Pacific herring density to habitat characteristics have been conducted. We sampled age-0 Pacific herring in nine bays and fjords distributed throughout Alaska's Prince William Sound during November over a 3-year period (2013-2015) and investigated associations between catch rate and habitat covariates using generalized linear mixed models. Our results indicated that the night-time distribution of age-0 Pacific herring in the pelagic environment was influenced by proximity to eelgrass (Zostera marina) beds, salinity, and water depth. Age-0 Pacific herring catch rate was negatively associated with tow depth, with herring favoring shallower water across the range of depths sampled (7.2-35.4 m). In addition, Pacific herring distribution was positively associated with fresher water within the sampled salinity gradient (24.1-32.3 psu) and proximity to eelgrass beds. Seasonal changes in juvenile Pacific herring distribution were investigated by sampling one bay over a seven month period (October-April). Age-0 Pacific herring tended to remain in the inner bay region throughout the seven months, while age-1 Pacific herring had shifted from the inner to the outer bay by spring (March-April). Additionally, catch rate of age-0 Pacific herring in areas where ice breakup had just occurred was higher than in open water, suggesting that age-0 herring preferentially select ice-covered habitats when available. Based on our results we recommend that habitat preferences of age-0 Pacific herring should be considered in the development of Pacific herring year-class strength indices from catch data.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21228597','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21228597"><span>Chemical production in electrocautery smoke by a novel predictive model.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Wu, Y-C; Tang, C-S; Huang, H-Y; Liu, C-H; Chen, Y-L; Chen, D-R; Lin, Y-W</p> <p>2011-01-01</p> <p>The hazards of electrocautery smoke have been known for decades. However, few clinical studies have been conducted to analyze the responsible variables of the smoke production. This study collected clinical smoke samples and systematically analyzed all possible factors. Thirty diathermy smoke samples were collected during mastectomy and abdominal cavity operations. Samples were analyzed using a gas chromatographer with a flame ionization detector. Data were applied to construct prediction models for chemical production from electrosurgeries to identify all possible factors that impact chemical production during electrosurgery. Toluene was detected in 27 smoke samples (90%) with concentrations of 0.003-0.463 mg/m(3) and production of 176.0-2,780.0 ng. Ethyl benzene and styrene were identified in very few cases. General linear regression analysis demonstrates that surgery type, patient age, electrocautery duration and imparted coagulation energy explained 67.63% of the variation in toluene production. Surgery type and patient age are known prior to surgery. In terms of risk precaution, the operating team should pay close attention to exposure when certain positive factors of increasing the chemical production are known in advance. Copyright © 2011 S. Karger AG, Basel.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29577701','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29577701"><span>[Automated Assessment for Bone Age of Left Wrist Joint in Uyghur Teenagers by Deep Learning].</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hu, T H; Huo, Z; Liu, T A; Wang, F; Wan, L; Wang, M W; Chen, T; Wang, Y H</p> <p>2018-02-01</p> <p>To realize the automated bone age assessment by applying deep learning to digital radiography （DR） image recognition of left wrist joint in Uyghur teenagers, and explore its practical application value in forensic medicine bone age assessment. The X-ray films of left wrist joint after pretreatment, which were taken from 245 male and 227 female Uyghur nationality teenagers in Uygur Autonomous Region aged from 13.0 to 19.0 years old, were chosen as subjects. And AlexNet was as a regression model of image recognition. From the total samples above, 60％ of male and female DR images of left wrist joint were selected as net train set, and 10％ of samples were selected as validation set. As test set, the rest 30％ were used to obtain the image recognition accuracy with an error range in ±1.0 and ±0.7 age respectively, compared to the real age. The modelling results of deep learning algorithm showed that when the error range was in ±1.0 and ±0.7 age respectively, the accuracy of the net train set was 81.4% and 75.6% in male, and 80.5% and 74.8% in female, respectively. When the error range was in ±1.0 and ±0.7 age respectively, the accuracy of the test set was 79.5% and 71.2% in male, and 79.4% and 66.2% in female, respectively. The combination of bone age research on teenagers' left wrist joint and deep learning, which has high accuracy and good feasibility, can be the research basis of bone age automatic assessment system for the rest joints of body. Copyright© by the Editorial Department of Journal of Forensic Medicine.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24670075','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24670075"><span>Exploratory and confirmatory factor analyses and demographic correlate models of the strategies for weight management measure for overweight or obese adults.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kolodziejczyk, Julia K; Norman, Gregory J; Roesch, Scott C; Rock, Cheryl L; Arredondo, Elva M; Madanat, Hala; Patrick, Kevin</p> <p>2015-01-01</p> <p>There is a need for a self-report measure that assesses use of recommended strategies related to weight management. Cross-sectional analysis. Universities, community. Exploratory factor analysis (EFA) involved data from 404 overweight/obese young adults (mean age = 22 years, 48% non-Hispanic white, 68% ethnic minority). Confirmatory factor analysis (CFA) involved data from 236 overweight/obese adults (mean age = 42 years, 63% non-Hispanic white, 84% ethnic minority). The Strategies for Weight Management (SWM) measure is a 35-item questionnaire that assesses use of recommended behavioral strategies for reducing energy intake and increasing energy expenditure in overweight/obese adults. EFA and CFA were conducted on the SWM. Correlate models assessed the associations between SWM factor/total scores and demographics by using linear regressions. EFA suggested a four-factor model: strategies categorized as targeting (1) energy intake, (2) energy expenditure, (3) self-monitoring, and (4) self-regulation. CFA indicated good model fit (χ(2)/df = 2.0, comparative fit index = .90, standardized root mean square residual = .06, and root mean square error of approximation = .07, confidence interval = .06-.08, R(2) = .11-.74). The fourth factor had the lowest loadings, possibly because the items cover a wide domain. The final model included 20 items. Correlate models revealed weak associations between the SWM scores and age, gender, Hispanic ethnicity, and relationship status in both samples, with the models explaining only 1% to 8% of the variance (betas = -.04 to .29, p < .05). The SWM has promising psychometric qualities in two diverse samples.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li class="active"><span>19</span></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_19 --> <div id="page_20" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li class="active"><span>20</span></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="381"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/16612025','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/16612025"><span>Consumer sensory acceptance and value of wet-aged and dry-aged beef steaks.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sitz, B M; Calkins, C R; Feuz, D M; Umberger, W J; Eskridge, K M</p> <p>2006-05-01</p> <p>To determine sensory preference and value of fresh beef steak differing in aging technique, strip steaks were evaluated by consumers in Denver (n = 132 consumers) and Chicago (n = 141 consumers). Wet-aged Choice strip loins were matched with dry-aged Choice strip loins, whereas wet-aged Prime strip loins were matched with dry-aged Prime strip loins. Dry-aged strip loins were commercially aged in air in a controlled environment for 30 d and vacuum-aged for 7 d during shipping and storage. Wet-aged strip loins were vacuum-packaged and aged for 37 d in a 1 degrees C cooler. Pairs of strip loins were matched to similar Warner-Bratzler shear force values and marbling scores. Twelve sensory evaluation panels (of 12 scheduled panelists each) were conducted over a 3-d period in each city. Individual samples from a pair of steaks were evaluated by the panelists for sensory traits. Bids were placed on the samples after sensory traits were obtained utilizing a variation of the Vickery auction with silent, sealed bids. No significant differences for sensory traits of flavor, juiciness, tenderness, or overall acceptability were detected between wet-aged Choice samples and dry-aged Choice samples. Although wet-aged Choice samples were numerically superior for all sensory traits, consumers placed similar bid values (P = 0.12) on wet- and dry-aged Choice samples ($3.82 per 0.45 kg and $3.57 per 0.45 kg, respectively). Wet-aged Prime samples were rated more desirable (P < 0.001) for flavor, tenderness, and overall acceptability than dry-aged Prime samples. Wet-aged Prime samples were valued at $4.02 per 0.45 kg, whereas dry-aged Prime samples brought $3.58 per 0.45 kg (P = 0.008). Consumers (29.3%) who preferred the dry-aged Choice samples over the wet-aged Choice samples were willing to pay $1.99/0.45 kg more (P < 0.001) for dry-aged samples. The consumers who preferred the wet-aged Choice over the dry-aged Choice samples (39.2%) were willing to pay $1.77/0.45 kg more (P < 0.0001). Consumers who preferred wet-aged Prime over dry-aged Prime samples (45.8%) paid $1.92/0.45 kg more (P < 0.0001). Consumers who preferred dry-aged Prime samples (27.5%) were willing to pay $1.92/0.45 kg more than for the wet-aged Prime samples. Although more consumers preferred wet-aged samples, markets do exist for dry-aged beef, and consumers are willing to pay a premium for this product.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70047104','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70047104"><span>Effects of dreissenids on monitoring and management of fisheries in western Lake Erie</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Stapanian, Martin A.; Kocovsky, Patrick M.</p> <p>2013-01-01</p> <p>Water clarity increased in nearshore areas of western Lake Erie by the early-1990s mainly as a result of the filtering activities of dreissenid mussels (Dreissena spp.), which invaded in the mid-1980s. We hypothesized that increased water clarity would result in greater trawl avoidance and thus reduced ability to capture fish in bottom trawls during daytime compared to nighttime. We examined this hypothesis by summarizing three analyses on fish data collected in western Lake Erie. First, we used a two-tiered modeling approach on the ration (R) of catch per hour (CPH) of age-0 yellow perch (Perca flavencens Mitchell) at night to CPH during daytime in 1961-2005. The best a priori and a posteriori models indicated a shift to higher CPH at night (R > 1) between 1990 and 1991, which corresponded to 3 years after the dreissenid invasion and when water clarity noticeably increased at nearshore sites. Secondly, we examined effects of nighttime sampling on estimates of abundance of age-2 and older yellow perch, which form the basis for recommended allowable harvest (RAH). When data from night sampling were included in models that predict abundance of age-2 yellow perch from indices of abundance of age-0 and age-1 yellow perch, predicted abundance was lower and model precision, as measured by r-squared, was higher compared to models that excluded data collected at night. Furthermore, the use of only CPH data collected at night typically resulted in lower estimates of abundance and more precise models compared to models that included CPH data collected during both daytime and nighttime. Thirdly, we used presence/absence data from paired bottom trawl samples to calculate an index of capture probability (or catchability) to determine if our ability to capture the four most common benthic species in western Lake Erie was affected by dreissenid-caused increased water clarity. Three species of fish(white perch, Morone americana Gmelin; yellow perch; and trout-perch, Percopsis omiscomaycus Walbaum) had lower mean daytime catchability than nighttime catchability after dreissenids became established, which supported the hypothesis of greater trawl avoidance during daytime following establishment of dreissenids. Results from freshwater drum (Aplodinotus grunniens Rafinesque) were opposite those of the other three species, which may be a result of behavioral shifts due to freshwater drum feeding on dreissenids mussels. Collectively, these three studies suggest that dreissenids indirectly affected our ability to assess fish populations, which further affects estimates of fish densities and relationships between indices of abundance and true abundance.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29164117','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29164117"><span>Active Aging in Very Old Age and the Relevance of Psychological Aspects.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Paúl, Constança; Teixeira, Laetitia; Ribeiro, Oscar</p> <p>2017-01-01</p> <p>Active aging encompasses a socially and individually designed mix of different domains that range from personal and familial, to social and professional. In being a key policy concept often focused on the young-old individuals, efforts in studying its dimensions in advanced ages have seldom been made. Nevertheless, there is a recognized need to promote adequate responses to the growing number of individuals reaching advanced ages and to recognize their specific dependability on health-related aspects, services attendance, social interactions, or on psychological characteristics for what it means to "age actively." This study provides a secondary analysis of data and follows the preceding work on the operationalization of the World Health Organization's (WHO) active aging model by means of an assessment protocol to measure which variables, within the model's determinants, contribute the most for an active aging process (1). Authors used the achieved model (composed by six factors: health, psychological component, cognitive performance, social relationships, biological component, and personality) and performed multi-group analysis of structural invariance to examine hypothetical differences between age groups (<75 years vs. ≥75 years) and to contrast obtained findings with the originally achieved model for the total sample (1,322 individuals aged 55 +). The structural covariances for the two age groups were statistically different. The comparison of components between age groups revealed a major relevance of the psychological component for the older age group. These findings reinforce the importance of psychological functioning in active aging in oldest old, and the need for further research on specific psychological features underlying the subjective meaning of active aging in more advanced ages.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26653757','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26653757"><span>Simultaneous fecal microbial and metabolite profiling enables accurate classification of pediatric irritable bowel syndrome.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Shankar, Vijay; Reo, Nicholas V; Paliy, Oleg</p> <p>2015-12-09</p> <p>We previously showed that stool samples of pre-adolescent and adolescent US children diagnosed with diarrhea-predominant IBS (IBS-D) had different compositions of microbiota and metabolites compared to healthy age-matched controls. Here we explored whether observed fecal microbiota and metabolite differences between these two adolescent populations can be used to discriminate between IBS and health. We constructed individual microbiota- and metabolite-based sample classification models based on the partial least squares multivariate analysis and then applied a Bayesian approach to integrate individual models into a single classifier. The resulting combined classification achieved 84 % accuracy of correct sample group assignment and 86 % prediction for IBS-D in cross-validation tests. The performance of the cumulative classification model was further validated by the de novo analysis of stool samples from a small independent IBS-D cohort. High-throughput microbial and metabolite profiling of subject stool samples can be used to facilitate IBS diagnosis.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5235964','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5235964"><span>Sexual Quality of Life and Aging: A Prospective Study of a Nationally Representative Sample</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Forbes, Miriam K.; Eaton, Nicholas R.; Krueger, Robert F.</p> <p>2016-01-01</p> <p>Unlike other life domains, sexual quality of life (SQoL) has a negative relationship with age. This study disentangled the effect of age in this relationship from confounding sociocultural influences (e.g., the period of time in which data were collected, and cohort differences), and aimed to understand the roles of other sexual domains (i.e., frequency, perceived control, thought and effort invested in sex, and number of sexual partners). We analyzed data from the longitudinal Midlife in the United States study (n = 6,278; age range 20–93), which were collected between 1995 and 2013. Repeated measures linear mixed-effects models showed that age was the most robust time-related predictor of declining SQoL. However, after the sexual domains were included in the model, age had a positive relationship with SQoL, and older adults’ SQoL was differentially influenced by the quality—not quantity—of sex. When partnership characteristics were included in the model, age was no longer related to SQoL. These findings suggest that aging may be associated with the acquisition of skills and strategies that can buffer age-related declines in SQoL, particularly in the context of a positive relationship. We summarize these findings as sexual wisdom. PMID:27798838</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27798838','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27798838"><span>Sexual Quality of Life and Aging: A Prospective Study of a Nationally Representative Sample.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Forbes, Miriam K; Eaton, Nicholas R; Krueger, Robert F</p> <p>2017-02-01</p> <p>Unlike other life domains, sexual quality of life (SQoL) has a negative relationship with age. This study disentangled the effect of age in this relationship from confounding sociocultural influences (e.g., the period of time in which data were collected, and cohort differences) and aimed to understand the roles of other sexual domains (i.e., frequency, perceived control, thought and effort invested in sex, and number of sexual partners). We analyzed data from the longitudinal Midlife in the United States study (n = 6,278; age range 20-93), which were collected between 1995 and 2013. Repeated measures linear mixed-effects models showed that age was the most robust time-related predictor of declining SQoL. However, after the sexual domains were included in the model, age had a positive relationship with SQoL and older adults' SQoL was differentially influenced by the quality-not quantity-of sex. When partnership characteristics were included in the model, age was no longer related to SQoL. These findings suggest that aging may be associated with the acquisition of skills and strategies that can buffer age-related declines in SQoL, particularly in the context of a positive relationship. We summarize these findings as sexual wisdom.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27149863','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27149863"><span>The role of pre-morbid intelligence and cognitive reserve in predicting cognitive efficiency in a sample of Italian elderly.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Caffò, Alessandro O; Lopez, Antonella; Spano, Giuseppina; Saracino, Giuseppe; Stasolla, Fabrizio; Ciriello, Giuseppe; Grattagliano, Ignazio; Lancioni, Giulio E; Bosco, Andrea</p> <p>2016-12-01</p> <p>Models of cognitive reserve in aging suggest that individual's life experience (education, working activity, and leisure) can exert a neuroprotective effect against cognitive decline and may represent an important contribution to successful aging. The objective of the present study is to investigate the role of cognitive reserve, pre-morbid intelligence, age, and education level, in predicting cognitive efficiency in a sample of healthy aged individuals and with probable mild cognitive impairment. Two hundred and eight aging participants recruited from the provincial region of Bari (Apulia, Italy) took part in the study. A battery of standardized tests was administered to them to measure cognitive reserve, pre-morbid intelligence, and cognitive efficiency. Protocols for 10 participants were excluded since they did not meet inclusion criteria, and statistical analyses were conducted on data from the remaining 198 participants. A path analysis was used to test the following model: age, education level, and intelligence directly influence cognitive reserve and cognitive efficiency; cognitive reserve mediates the influence of age, education level, and intelligence on cognitive efficiency. Cognitive reserve fully mediates the relationship between pre-morbid intelligence and education level and cognitive efficiency, while age maintains a direct effect on cognitive efficiency. Cognitive reserve appears to exert a protective effect regarding cognitive decline in normal and pathological populations, thus masking, at least in the early phases of neurodegeneration, the decline of memory, orientation, attention, language, and reasoning skills. The assessment of cognitive reserve may represent a useful evaluation supplement in neuropsychological screening protocols of cognitive decline.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1305898-corrigendum-evidence-shock-heating-constraints-martian-surface-temperatures-revealed-thermochronometry-martian-meteorites-geochim-cosmochim-acta','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1305898-corrigendum-evidence-shock-heating-constraints-martian-surface-temperatures-revealed-thermochronometry-martian-meteorites-geochim-cosmochim-acta"><span>Corrigendum to ‘Evidence for shock heating and constraints on Martian surface temperatures revealed by 40Ar/ 39Ar thermochronometry of Martian meteorites’ [Geochim. Cosmochim. Acta (2010) 6900–6920</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a></p> <p>Cassata, William S.; Shuster, David L.; Renne, Paul R.; ...</p> <p>2014-10-23</p> <p>Here, the authors regret they have discovered errors in Eq. (3) and in a spreadsheet used to calculate cosmogenic exposure ages shown in Table 1. Eq. (3) is missing a term. The spreadsheet errors concerned an incorrect cell reference and application of Eq. (3). Correction of these errors results in ~15–20% changes to the exposure ages of all samples, minor (generally <0.2%) changes to the radioisotopic ages of some samples (those that entailed a correction for chlorine-derived 38Ar calculated based on the exposure age; see Section 3.3), and statistically insignificant changes to the inferred trapped components identified through isochron analyses.more » These modifications have no impact on the modeling, discussions, or conclusions in the paper, nor do the changes to radioisotopic ages exceed the 1 sigma uncertainties.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24127053','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24127053"><span>[Willingness to accept an Internet-based mobility platform in different age cohorts. Empiric results of the project S-Mobil 100].</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Beil, J; Cihlar, V; Kruse, A</p> <p>2015-02-01</p> <p>The aim of the project S-Mobil 100 is to develop and implement a prototype of an internet-based, generation-appropriate mobility platform in the model region Siegen-Wittgenstein. In the context of an empirical preliminary study, use of technology, experience with technology, general attitudes towards technology, general technology commitment, and the willingness to accept the mobility platform were investigated in different age cohorts. The investigation was carried out using a written survey based on a standardized questionnaire. The sample of 358 persons aged 40-90 years was divided in four age cohorts (40-54, 55-64, 65-74, and 75 + years). Our results show a high willingness to accept the mobility platform in the overall sample. Age, residence, income, and general technology commitment were significant predictors for the judgment of the platform. Although there were group differences in accepting the mobility platform, the older cohorts are also open-minded towards this new technology.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3686781','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3686781"><span>Aging, Maturation and Growth of Sauropodomorph Dinosaurs as Deduced from Growth Curves Using Long Bone Histological Data: An Assessment of Methodological Constraints and Solutions</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Griebeler, Eva Maria; Klein, Nicole; Sander, P. Martin</p> <p>2013-01-01</p> <p>Information on aging, maturation, and growth is important for understanding life histories of organisms. In extinct dinosaurs, such information can be derived from the histological growth record preserved in the mid-shaft cortex of long bones. Here, we construct growth models to estimate ages at death, ages at sexual maturity, ages at which individuals were fully-grown, and maximum growth rates from the growth record preserved in long bones of six sauropod dinosaur individuals (one indeterminate mamenchisaurid, two Apatosaurus sp., two indeterminate diplodocids, and one Camarasaurus sp.) and one basal sauropodomorph dinosaur individual (Plateosaurus engelhardti). Using these estimates, we establish allometries between body mass and each of these traits and compare these to extant taxa. Growth models considered for each dinosaur individual were the von Bertalanffy model, the Gompertz model, and the logistic model (LGM), all of which have inherently fixed inflection points, and the Chapman-Richards model in which the point is not fixed. We use the arithmetic mean of the age at the inflection point and of the age at which 90% of asymptotic mass is reached to assess respectively the age at sexual maturity or the age at onset of reproduction, because unambiguous indicators of maturity in Sauropodomorpha are lacking. According to an AIC-based model selection process, the LGM was the best model for our sauropodomorph sample. Allometries established are consistent with literature data on other Sauropodomorpha. All Sauropodomorpha reached full size within a time span similar to scaled-up modern mammalian megaherbivores and had similar maximum growth rates to scaled-up modern megaherbivores and ratites, but growth rates of Sauropodomorpha were lower than of an average mammal. Sauropodomorph ages at death probably were lower than that of average scaled-up ratites and megaherbivores. Sauropodomorpha were older at maturation than scaled-up ratites and average mammals, but younger than scaled-up megaherbivores. PMID:23840575</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23840575','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23840575"><span>Aging, Maturation and Growth of Sauropodomorph Dinosaurs as Deduced from Growth Curves Using Long Bone Histological Data: An Assessment of Methodological Constraints and Solutions.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Griebeler, Eva Maria; Klein, Nicole; Sander, P Martin</p> <p>2013-01-01</p> <p>Information on aging, maturation, and growth is important for understanding life histories of organisms. In extinct dinosaurs, such information can be derived from the histological growth record preserved in the mid-shaft cortex of long bones. Here, we construct growth models to estimate ages at death, ages at sexual maturity, ages at which individuals were fully-grown, and maximum growth rates from the growth record preserved in long bones of six sauropod dinosaur individuals (one indeterminate mamenchisaurid, two Apatosaurus sp., two indeterminate diplodocids, and one Camarasaurus sp.) and one basal sauropodomorph dinosaur individual (Plateosaurus engelhardti). Using these estimates, we establish allometries between body mass and each of these traits and compare these to extant taxa. Growth models considered for each dinosaur individual were the von Bertalanffy model, the Gompertz model, and the logistic model (LGM), all of which have inherently fixed inflection points, and the Chapman-Richards model in which the point is not fixed. We use the arithmetic mean of the age at the inflection point and of the age at which 90% of asymptotic mass is reached to assess respectively the age at sexual maturity or the age at onset of reproduction, because unambiguous indicators of maturity in Sauropodomorpha are lacking. According to an AIC-based model selection process, the LGM was the best model for our sauropodomorph sample. Allometries established are consistent with literature data on other Sauropodomorpha. All Sauropodomorpha reached full size within a time span similar to scaled-up modern mammalian megaherbivores and had similar maximum growth rates to scaled-up modern megaherbivores and ratites, but growth rates of Sauropodomorpha were lower than of an average mammal. Sauropodomorph ages at death probably were lower than that of average scaled-up ratites and megaherbivores. Sauropodomorpha were older at maturation than scaled-up ratites and average mammals, but younger than scaled-up megaherbivores.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=seniors+OR+older+AND+adults+OR+elderly+OR+geriatric+OR+aged+AND+health&pg=3&id=EJ944128','ERIC'); return false;" href="https://eric.ed.gov/?q=seniors+OR+older+AND+adults+OR+elderly+OR+geriatric+OR+aged+AND+health&pg=3&id=EJ944128"><span>Subjective Values of Quality of Life Dimensions in Elderly People. A SEM Preference Model Approach</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Elosua, Paula</p> <p>2011-01-01</p> <p>This article proposes a Thurstonian model in the framework of Structural Equation Modelling (SEM) to assess preferences among quality of life dimensions for the elderly. Data were gathered by a paired comparison design in a sample comprised of 323 people aged from 65 to 94 years old. Five dimensions of quality of life were evaluated: Health,…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4091996','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4091996"><span>Associations of Sexual Victimization, Depression, and Sexual Assertiveness with Unprotected Sex: A Test of the Multifaceted Model of HIV Risk Across Gender</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Morokoff, Patricia J.; Redding, Colleen A.; Harlow, Lisa L.; Cho, Sookhyun; Rossi, Joseph S.; Meier, Kathryn S.; Mayer, Kenneth H.; Koblin, Beryl; Brown-Peterside, Pamela</p> <p>2014-01-01</p> <p>This study examined whether the Multifaceted Model of HIV Risk (MMOHR) would predict unprotected sex based on predictors including gender, childhood sexual abuse (CSA), sexual victimization (SV), depression, and sexual assertiveness for condom use. A community-based sample of 473 heterosexually active men and women, aged 18–46 years completed survey measures of model variables. Gender predicted several variables significantly. A separate model for women demonstrated excellent fit, while the model for men demonstrated reasonable fit. Multiple sample model testing supported the use of MMOHR in both men and women, while simultaneously highlighting areas of gender difference. Prevention interventions should focus on sexual assertiveness, especially for CSA and SV survivors, as well as targeting depression, especially among men. PMID:25018617</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018MNRAS.477.5191R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018MNRAS.477.5191R"><span>Circumstellar disc lifetimes in numerous galactic young stellar clusters</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Richert, A. J. W.; Getman, K. V.; Feigelson, E. D.; Kuhn, M. A.; Broos, P. S.; Povich, M. S.; Bate, M. R.; Garmire, G. P.</p> <p>2018-07-01</p> <p>Photometric detections of dust circumstellar discs around pre-main sequence (PMS) stars, coupled with estimates of stellar ages, provide constraints on the time available for planet formation. Most previous studies on disc longevity, starting with Haisch, Lada & Lada, use star samples from PMS clusters but do not consider data sets with homogeneous photometric sensitivities and/or ages placed on a uniform time-scale. Here we conduct the largest study to date of the longevity of inner dust discs using X-ray and 1-8 µm infrared photometry from the MYStIX and SFiNCs projects for 69 young clusters in 32 nearby star-forming regions with ages t ≤ 5 Myr. Cluster ages are derived by combining the empirical AgeJX method with PMS evolutionary models, which treat dynamo-generated magnetic fields in different ways. Leveraging X-ray data to identify disc-free objects, we impose similar stellar mass sensitivity limits for disc-bearing and disc-free young stellar objects while extending the analysis to stellar masses as low as M ˜ 0.1 M⊙. We find that the disc longevity estimates are strongly affected by the choice of PMS evolutionary model. Assuming a disc fraction of 100 per cent at zero age, the inferred disc half-life changes significantly, from t1/2 ˜ 1.3-2 Myr to t1/2 ˜ 3.5 Myr when switching from non-magnetic to magnetic PMS models. In addition, we find no statistically significant evidence that disc fraction varies with stellar mass within the first few Myr of life for stars with masses <2 M⊙, but our samples may not be complete for more massive stars. The effects of initial disc fraction and star-forming environment are also explored.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018MNRAS.476.2465O','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018MNRAS.476.2465O"><span>The solar wind in time: a change in the behaviour of older winds?</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>O'Fionnagáin, D.; Vidotto, A. A.</p> <p>2018-05-01</p> <p>In this paper, we model the wind of solar analogues at different ages to investigate the evolution of the solar wind. Recently, it has been suggested that winds of solar type stars might undergo a change in properties at old ages, whereby stars older than the Sun would be less efficient in carrying away angular momentum than what was traditionally believed. Adding to this, recent observations suggest that old solar-type stars show a break in coronal properties, with a steeper decay in X-ray luminosities and temperatures at older ages. We use these X-ray observations to constrain the thermal acceleration of winds of solar analogues. Our sample is based on the stars from the `Sun in Time' project with ages between 120 and 7000 Myr. The break in X-ray properties leads to a break in wind mass-loss rates (\\dot{M}) at roughly 2 Gyr, with \\dot{M} (t < 2 Gyr) ∝ t-0.74 and \\dot{M} (t > 2 Gyr) ∝ t-3.9. This steep decay in \\dot{M} at older ages could be the reason why older stars are less efficient at carrying away angular momentum, which would explain the anomalously rapid rotation observed in older stars. We also show that none of the stars in our sample would have winds dense enough to produce thermal emission above 1-2 GHz, explaining why their radio emissions have not yet been detected. Combining our models with dynamo evolution models for the magnetic field of the Earth, we find that, at early ages (≈100 Myr), our Earth had a magnetosphere that was three or more times smaller than its current size.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018MNRAS.tmp..923R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018MNRAS.tmp..923R"><span>Circumstellar Disk Lifetimes In Numerous Galactic Young Stellar Clusters</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Richert, A. J. W.; Getman, K. V.; Feigelson, E. D.; Kuhn, M. A.; Broos, P. S.; Povich, M. S.; Bate, M. R.; Garmire, G. P.</p> <p>2018-04-01</p> <p>Photometric detections of dust circumstellar disks around pre-main sequence (PMS) stars, coupled with estimates of stellar ages, provide constraints on the time available for planet formation. Most previous studies on disk longevity, starting with Haisch, Lada & Lada (2001), use star samples from PMS clusters but do not consider datasets with homogeneous photometric sensitivities and/or ages placed on a uniform timescale. Here we conduct the largest study to date of the longevity of inner dust disks using X-ray and 1-8 {μ m} infrared photometry from the MYStIX and SFiNCs projects for 69 young clusters in 32 nearby star-forming regions with ages t ≤ 5 Myr. Cluster ages are derived by combining the empirical AgeJX method with PMS evolutionary models, which treat dynamo-generated magnetic fields in different ways. Leveraging X-ray data to identify disk-free objects, we impose similar stellar mass sensitivity limits for disk-bearing and disk-free YSOs while extending the analysis to stellar masses as low as M ˜ 0.1 M⊙. We find that the disk longevity estimates are strongly affected by the choice of PMS evolutionary model. Assuming a disk fraction of 100% at zero age, the inferred disk half-life changes significantly, from t1/2 ˜ 1.3 - 2 Myr to t1/2 ˜ 3.5 Myr when switching from non-magnetic to magnetic PMS models. In addition, we find no statistically significant evidence that disk fraction varies with stellar mass within the first few Myr of life for stars with masses <2 M⊙, but our samples may not be complete for more massive stars. The effects of initial disk fraction and star-forming environment are also explored.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014AGUFM.B43D0285L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014AGUFM.B43D0285L"><span>Uncertainty in accounting for carbon accumulation following forest harvesting</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Lilly, P.; Yanai, R. D.; Arthur, M. A.; Bae, K.; Hamburg, S.; Levine, C. R.; Vadeboncoeur, M. A.</p> <p>2014-12-01</p> <p>Tree biomass and forest soils are both difficult to quantify with confidence, for different reasons. Forest biomass is estimated non-destructively using allometric equations, often from other sites; these equations are difficult to validate. Forest soils are destructively sampled, resulting in little measurement error at a point, but with large sampling error in heterogeneous soil environments, such as in soils developed on glacial till. In this study, we report C contents of biomass and soil pools in northern hardwood stands in replicate plots within replicate stands in 3 age classes following clearcut harvesting (14-19 yr, 26-29 yr, and > 100 yr) at the Bartlett Experimental Forest, USA. The rate of C accumulation in aboveground biomass was ~3 Mg/ha/yr between the young and mid-aged stands and <1 Mg/ha/yr between the mid-aged and mature stands. We propagated model uncertainty through allometric equations, and found errors ranging from 3-7%, depending on the stand. The variation in biomass among plots within stands (6-19%) was always larger than the allometric uncertainties. Soils were described by quantitative soil pits in three plots per stand, excavated by depth increment to the C horizon. Variation in soil mass among pits within stands averaged 28% (coefficient of variation); variation among stands within an age class ranged from 9-25%. Variation in carbon concentrations averaged 27%, mainly because the depth increments contained varying proportions of genetic horizons, in the upper part of the soil profile. Differences across age classes in soil C were not significant, because of the high variability. Uncertainty analysis can help direct the design of monitoring schemes to achieve the greatest confidence in C stores per unit of sampling effort. In the system we studied, more extensive sampling would be the best approach to reducing uncertainty, as natural spatial variation was higher than model or measurement uncertainties.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29163325','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29163325"><span>An Illustration of the Exploratory Structural Equation Modeling (ESEM) Framework on the Passion Scale.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Tóth-Király, István; Bõthe, Beáta; Rigó, Adrien; Orosz, Gábor</p> <p>2017-01-01</p> <p>While exploratory factor analysis (EFA) provides a more realistic presentation of the data with the allowance of item cross-loadings, confirmatory factor analysis (CFA) includes many methodological advances that the former does not. To create a synergy of the two, exploratory structural equation modeling (ESEM) was proposed as an alternative solution, incorporating the advantages of EFA and CFA. The present investigation is thus an illustrative demonstration of the applicability and flexibility of ESEM. To achieve this goal, we compared CFA and ESEM models, then thoroughly tested measurement invariance and differential item functioning through multiple-indicators-multiple-causes (MIMIC) models on the Passion Scale, the only measure of the Dualistic Model of Passion (DMP) which differentiates between harmonious and obsessive forms of passion. Moreover, a hybrid model was also created to overcome the drawbacks of the two methods. Analyses of the first large community sample ( N = 7,466; 67.7% females; M age = 26.01) revealed the superiority of the ESEM model relative to CFA in terms of improved goodness-of-fit and less correlated factors, while at the same time retaining the high definition of the factors. However, this fit was only achieved with the inclusion of three correlated uniquenesses, two of which appeared in previous studies and one of which was specific to the current investigation. These findings were replicated on a second, comprehensive sample ( N = 504; 51.8% females; M age = 39.59). After combining the two samples, complete measurement invariance (factor loadings, item intercepts, item uniquenesses, factor variances-covariances, and latent means) was achieved across gender and partial invariance across age groups and their combination. Only one item intercept was non-invariant across both multigroup and MIMIC approaches, an observation that was further corroborated by the hybrid model. While obsessive passion showed a slight decline in the hybrid model, harmonious passion did not. Overall, the ESEM framework is a viable alternative of CFA that could be used and even extended to address substantially important questions and researchers should systematically compare these two approaches to identify the most suitable one.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5572771','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5572771"><span>Neonatal Maturation of Paracetamol (Acetaminophen) Glucuronidation, Sulfation, and Oxidation Based on a Parent-Metabolite Population Pharmacokinetic Model</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Cook, Sarah F.; Stockmann, Chris; Samiee-Zafarghandy, Samira; King, Amber D.; Deutsch, Nina; Williams, Elaine F.; Wilkins, Diana G.; van den Anker, John N.</p> <p>2017-01-01</p> <p>Objectives This study aimed to model the population pharmacokinetics of intravenous paracetamol and its major metabolites in neonates and to identify influential patient characteristics, especially those affecting the formation clearance (CLformation) of oxidative pathway metabolites. Methods Neonates with a clinical indication for intravenous analgesia received five 15-mg/kg doses of paracetamol at 12-h intervals (<28 weeks’ gestation) or seven 15-mg/kg doses at 8-h intervals (≥28 weeks’ gestation). Plasma and urine were sampled throughout the 72-h study period. Concentration-time data for paracetamol, paracetamol-glucuronide, paracetamol-sulfate, and the combined oxidative pathway metabolites (paracetamol-cysteine and paracetamol-N-acetylcysteine) were simultaneously modeled in NONMEM 7.2. Results The model incorporated 259 plasma and 350 urine samples from 35 neonates with a mean gestational age of 33.6 weeks (standard deviation 6.6). CLformation for all metabolites increased with weight; CLformation for glucuronidation and oxidation also increased with postnatal age. At the mean weight (2.3 kg) and postnatal age (7.5 days), CLformation estimates (bootstrap 95% confidence interval; between-subject variability) were 0.049 L/h (0.038–0.062; 62 %) for glucuronidation, 0.21 L/h (0.17–0.24; 33 %) for sulfation, and 0.058 L/h (0.044–0.078; 72 %) for oxidation. Expression of individual oxidation CLformation as a fraction of total individual paracetamol clearance showed that, on average, fractional oxidation CLformation increased <15 % when plotted against weight or postnatal age. Conclusions The parent-metabolite model successfully characterized the pharmacokinetics of intravenous paracetamol and its metabolites in neonates. Maturational changes in the fraction of paracetamol undergoing oxidation were small relative to between-subject variability. PMID:27209292</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27209292','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27209292"><span>Neonatal Maturation of Paracetamol (Acetaminophen) Glucuronidation, Sulfation, and Oxidation Based on a Parent-Metabolite Population Pharmacokinetic Model.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Cook, Sarah F; Stockmann, Chris; Samiee-Zafarghandy, Samira; King, Amber D; Deutsch, Nina; Williams, Elaine F; Wilkins, Diana G; Sherwin, Catherine M T; van den Anker, John N</p> <p>2016-11-01</p> <p>This study aimed to model the population pharmacokinetics of intravenous paracetamol and its major metabolites in neonates and to identify influential patient characteristics, especially those affecting the formation clearance (CL formation ) of oxidative pathway metabolites. Neonates with a clinical indication for intravenous analgesia received five 15-mg/kg doses of paracetamol at 12-h intervals (<28 weeks' gestation) or seven 15-mg/kg doses at 8-h intervals (≥28 weeks' gestation). Plasma and urine were sampled throughout the 72-h study period. Concentration-time data for paracetamol, paracetamol-glucuronide, paracetamol-sulfate, and the combined oxidative pathway metabolites (paracetamol-cysteine and paracetamol-N-acetylcysteine) were simultaneously modeled in NONMEM 7.2. The model incorporated 259 plasma and 350 urine samples from 35 neonates with a mean gestational age of 33.6 weeks (standard deviation 6.6). CL formation for all metabolites increased with weight; CL formation for glucuronidation and oxidation also increased with postnatal age. At the mean weight (2.3 kg) and postnatal age (7.5 days), CL formation estimates (bootstrap 95% confidence interval; between-subject variability) were 0.049 L/h (0.038-0.062; 62 %) for glucuronidation, 0.21 L/h (0.17-0.24; 33 %) for sulfation, and 0.058 L/h (0.044-0.078; 72 %) for oxidation. Expression of individual oxidation CL formation as a fraction of total individual paracetamol clearance showed that, on average, fractional oxidation CL formation increased <15 % when plotted against weight or postnatal age. The parent-metabolite model successfully characterized the pharmacokinetics of intravenous paracetamol and its metabolites in neonates. Maturational changes in the fraction of paracetamol undergoing oxidation were small relative to between-subject variability.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li class="active"><span>20</span></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_20 --> <div id="page_21" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li class="active"><span>21</span></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="401"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29317003','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29317003"><span>Identification of Heterogeneous Cognitive Subgroups in Community-Dwelling Older Adults: A Latent Class Analysis of the Einstein Aging Study.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Zammit, Andrea R; Hall, Charles B; Lipton, Richard B; Katz, Mindy J; Muniz-Terrera, Graciela</p> <p>2018-05-01</p> <p>The aim of this study was to identify natural subgroups of older adults based on cognitive performance, and to establish each subgroup's characteristics based on demographic factors, physical function, psychosocial well-being, and comorbidity. We applied latent class (LC) modeling to identify subgroups in baseline assessments of 1345 Einstein Aging Study (EAS) participants free of dementia. The EAS is a community-dwelling cohort study of 70+ year-old adults living in the Bronx, NY. We used 10 neurocognitive tests and 3 covariates (age, sex, education) to identify latent subgroups. We used goodness-of-fit statistics to identify the optimal class solution and assess model adequacy. We also validated our model using two-fold split-half cross-validation. The sample had a mean age of 78.0 (SD=5.4) and a mean of 13.6 years of education (SD=3.5). A 9-class solution based on cognitive performance at baseline was the best-fitting model. We characterized the 9 identified classes as (i) disadvantaged, (ii) poor language, (iii) poor episodic memory and fluency, (iv) poor processing speed and executive function, (v) low average, (vi) high average, (vii) average, (viii) poor executive and poor working memory, (ix) elite. The cross validation indicated stable class assignment with the exception of the average and high average classes. LC modeling in a community sample of older adults revealed 9 cognitive subgroups. Assignment of subgroups was reliable and associated with external validators. Future work will test the predictive validity of these groups for outcomes such as Alzheimer's disease, vascular dementia and death, as well as markers of biological pathways that contribute to cognitive decline. (JINS, 2018, 24, 511-523).</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017EGUGA..1911370M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017EGUGA..1911370M"><span>Calibrating binary lumped parameter models</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Morgenstern, Uwe; Stewart, Mike</p> <p>2017-04-01</p> <p>Groundwater at its discharge point is a mixture of water from short and long flowlines, and therefore has a distribution of ages rather than a single age. Various transfer functions describe the distribution of ages within the water sample. Lumped parameter models (LPMs), which are mathematical models of water transport based on simplified aquifer geometry and flow configuration can account for such mixing of groundwater of different age, usually representing the age distribution with two parameters, the mean residence time, and the mixing parameter. Simple lumped parameter models can often match well the measured time varying age tracer concentrations, and therefore are a good representation of the groundwater mixing at these sites. Usually a few tracer data (time series and/or multi-tracer) can constrain both parameters. With the building of larger data sets of age tracer data throughout New Zealand, including tritium, SF6, CFCs, and recently Halon-1301, and time series of these tracers, we realised that for a number of wells the groundwater ages using a simple lumped parameter model were inconsistent between the different tracer methods. Contamination or degradation of individual tracers is unlikely because the different tracers show consistent trends over years and decades. This points toward a more complex mixing of groundwaters with different ages for such wells than represented by the simple lumped parameter models. Binary (or compound) mixing models are able to represent a more complex mixing, with mixing of water of two different age distributions. The problem related to these models is that they usually have 5 parameters which makes them data-hungry and therefore difficult to constrain all parameters. Two or more age tracers with different input functions, with multiple measurements over time, can provide the required information to constrain the parameters of the binary mixing model. We obtained excellent results using tritium time series encompassing the passage of the bomb-tritium through the aquifer, and SF6 with its steep gradient currently in the input. We will show age tracer data from drinking water wells that enabled identification of young water ingression into wells, which poses the risk of bacteriological contamination from the surface into the drinking water.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AGUFM.T23C0627P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AGUFM.T23C0627P"><span>Provenance of the exotic Northern Sierra terrane (North American Cordillera) based on U-Pb detrital zircon data</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Powerman, V.; Girty, G.; Hanson, R. E.; Grove, M.; Miller, E. L.; Hourigan, J. K.</p> <p>2017-12-01</p> <p>Ages of detrital zircons from the Northern Sierra terrane (NST) suggest an exotic provenance with respect to NW Laurentia. We have acquired U-Pb LA-ICPMS dz ages from 16 samples collected from the uppermost NST allochthon, the Sierra City mélange, and 1 sample from the lower Culbertson Lake allochthon. Age distributions can be divided into 3 partly intersecting groups: (a) 6 mélange samples and the 1 Culbertson Lake allochthon sample are dominated by >1 Ga grains; (b)5 samples are characterized by the additional presence of Early Paleozoic and Neoproterozoic grains (520-640;680-800;840-1000Ma); (c) 9 samples, 8 feldspathic, 1—qtz-rich, can be also characterized by the presence of 360-520Ma grains. These results strengthen the non Laurentian nature of detrital sources:(1)most of the detrital age distributions possess ages in the 1.49-1.61Ga interval, the "N.American magmatic gap";(2) Ediacaran zircons cannot be linked to any igneous event within West Laurentia. Most samples possess detrital age distributions that include the 1.0-2.0 Ga peak, characteristic of Baltica rather than Laurentia. These data, supplemented by SHRIMP-RG data (353-368Ma) from stitching igneous units suggest the following model: parts of NST were located at the NE margin of Baltica in the early Paleozoic, receiving "Baltica" (1.0-2.0 Ga) and "Timanide"(Late Vendian — Early Cambrian) zircons. This crustal block was later rifted away from Baltica and by mid-Paleozoic was juxtaposed with allochthons of presumably NW Laurentia provenance. The assembled terrane was involved in a subduction zone, resulting in the emplacement of 353-368Ma igneous rocks. The U-Pb detrital zircon age distributions presented here are similar to signatures of strata in along strike exotic terranes of the North American Cordillera (such as the Yreka terrane of the Klamath Mts., the Alexander terrane of S.Alaska and the Arctic Chukotka-Alaska terrane) by having Timanian, Baltica, and Caledonian signatures. Hence, it is likely that these blocks once shared a similar geologic history and have subsequently been displaced to their current positions.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.usgs.gov/sir/2011/5146/','USGSPUBS'); return false;" href="https://pubs.usgs.gov/sir/2011/5146/"><span>Hydrogeology, chemical characteristics, and water sources and pathways in the zone of contribution of a public-supply well in San Antonio, Texas</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Musgrove, MaryLynn; Fahlquist, Lynne; Stanton, Gregory P.; Houston, Natalie A.; Lindgren, Richard J.</p> <p>2011-01-01</p> <p>In 2001, the National Water-Quality Assessment (NAWQA) Program of the U.S. Geological Survey initiated a series of studies on the transport of anthropogenic and natural contaminants (TANC) to public-supply wells (PSWs). The main goal of the TANC project was to better understand the source, transport, and receptor factors that control contaminant movement to PSWs in representative aquifers of the United States. Regional- and local-scale study areas were selected from within existing NAWQA study units, including the south-central Texas Edwards aquifer. The local-scale TANC study area, nested within the regional-scale NAWQA study area, is representative of the regional Edwards aquifer. The PSW selected for study is within a well field of six production wells. Although a single PSW was initially selected, because of constraints of well-field operation, samples were collected from different wells within the well field for different components of the study. Data collected from all of the well-field wells were considered comparable because of similar well construction, hydrogeology, and geochemistry. An additional 38 PSWs (mostly completed in the confined part of the aquifer) were sampled throughout the regional aquifer to characterize water quality. Two monitoring well clusters, with wells completed at different depths, were installed to the east and west of the well field (the Zarzamora and Timberhill monitoring well clusters, respectively). One of the monitoring wells was completed in the overburden to evaluate potential hydrologic connectivity with the Edwards aquifer. Geophysical and flowmeter logs were collected from one of the well-field PSWs to determine zones of contribution to the wellbore. These contributing zones, associated with different hydrogeologic units, were used to select monitoring well completion depths and groundwater sample collection depths for depth-dependent sampling. Depth-dependent samples were collected from the PSW from three different depths and under three different pumping conditions. Additionally, selected monitoring wells and one of the well-field PSWs were sampled several times in response to a rainfall and recharge event to assess short-term (event-scale) temporal variations in water quality. For comparison purposes, groundwater samples were categorized as being from regional aquifer PSWs, from the well field (wellhead samples), from the monitoring wells (excluding the overburden well), from the overburden well, from the PSW depth-dependent sampling, and from temporal sampling. Groundwater samples were analyzed for inorganic, organic, isotopic, and age-dating tracers to characterize geochemical conditions in the aquifer and provide understanding of the mechanisms of mobilization and movement of selected constituents from source areas to a PSW. Sources, tracers, and conditions used to assess water quality and processes affecting the PSW and the aquifer system included (1) carbonate host rock composition; (2) physicochemical constituents; (3) major and trace element concentrations; (4) saturation indices with respect to minerals in aquifer rocks; (5) elemental ratios, such as magnesium to calcium ratios, that are indicative of water-rock interaction processes; (6) oxidation-reduction conditions; (7) nutrient concentrations, in particular nitrate concentrations; (8) the isotopic composition of nitrate, which can point to specific nitrate sources; (9) strontium isotopes; (10) stable isotopes of hydrogen and oxygen; (11) organic contaminant concentrations, including pesticides and volatile organic compounds; (12) age tracers, apparent-age distribution, and dissolved gas data used in age interpretations; (13) depth-dependent water chemistry collected from the PSW under different pumping conditions to assess zones of contribution; and (14) temporal variability in groundwater composition from the PSW and selected monitoring wells in response to an aquifer recharge event. Geochemical results indicate that the well-field and monitoring well samples were largely representative of groundwater in the regional confined aquifer. Constituents of concern in the Edwards aquifer for the long-term sustainability of the groundwater resource include the nutrient nitrate and anthropogenic organic contaminants. Nitrate concentrations (as nitrogen) for regional aquifer PSWs had a median value of 1.9 milligrams per liter, which is similar to previously reported values for the regional aquifer. Nitrate-isotope compositions for groundwater samples collected from the well-field PSWs and monitoring wells had a narrow range, with values indicative of natural soil organic values. A comparison with historical nitrate-isotope values, however, suggests that a component of nitrate in groundwater from biogenic sources might have increased over the last 30 years. Several organic contaminants (the pesticide atrazine, its degradate deethylatrazine, trichloromethane (chloroform; a drinking-water disinfection byproduct), and the solvent tetrachloroethene (PCE)) were widely distributed throughout the regional aquifer and in the local-scale TANC study area at low concentrations (less than 1 microgram per liter). Higher concentrations of PCE were detected in samples from the well-field PSWs and Zarzamora monitoring wells relative to the regional aquifer PSWs. The urban environment is a likely source of contaminants to the aquifer, and these results indicate that one or more local urban sources might be supplying PCE to the Zarzamora monitoring wells and the well-field wells. Samples from the well field also had high concentrations of chloroform relative to the monitoring wells and regional aquifer PSWs. For samples from the regional aquifer PSWs, the most frequently detected organic contaminants generally decreased in concentration with increasing well depth. Deeper wells might intercept longer regional flow paths with higher fractions of older water or water recharged in rural recharge areas in the western part of the aquifer that have been less affected by anthropogenic contaminants. A scenario of hypothetical contaminant loading was evaluated by using results from groundwater-flow-model particle tracking to assess the response of the aquifer to potential contamination. Results indicate that the aquifer responds quickly (less than 1 year to several years) to contaminant loading; however, it takes a relatively long time (decades) for concentrations to reach peak values. The aquifer also responds quickly (less than 1 year to several years) to the removal of contaminant loading; however, it also takes a relatively long time (decades) to reach near background concentrations. Interpretation of geochemical age tracers in this well-mixed karst system was complicated by contamination of a majority of measured tracers and complexities of extensive mixing. Age-tracer results generally indicated that groundwater samples were composed of young, recently recharged water with piston-flow model ages ranging from less than 1 to 41 years, with a median of 17 years. Although a piston-flow model is typically not valid for karst aquifers, the model ages provide a basis for comparing relative ages of different samples and a reference point for more complex hydrogeologic models for apparent-age interpretations. Young groundwater ages are consistent with particle-tracking results from hydrogeologic modeling for the local-scale TANC study area. Age-tracer results compared poorly with other geochemical indicators of groundwater residence time and anthropogenic effects on water quality, indicating that hydrogeologic conceptual models used in groundwater age interpretations might not adequately account for mixing in this karst system. Groundwater samples collected from the well field under a variety of pumping conditions were relatively homogeneous and well mixed for numerous geochemical constituents (with the notable exception of age tracers). Groundwater contributions to the PSW were dominated by well-mixed, relatively homogeneous groundwater, typical of the regional confined aquifer. Zones of preferential flow were determined for the PSW, but groundwater samples from different stratigraphic units were not geochemically distinct. Variations in chemical constituents in response to a rainfall and aquifer recharge event occurred but were relatively minor in the PSW and monitoring wells. This observation is consistent with the hypothesis that the response to individual recharge events in the confined aquifer, unless intersecting conduit flow paths, might be attenuated by mixing processes along regional flow paths. Results of this study are consistent with the existing conceptual understanding of aquifer processes in this karst system and are useful for water-resource development and management practices.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3769518','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3769518"><span>Determining Population and Developmental Pharmacokinetics of Metronidazole Using Plasma and Dried Blood Spot Samples from Premature Infants</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Cohen-Wolkowiez, Michael; Sampson, Mario; Bloom, Barry T.; Arrieta, Antonio; Wynn, James L.; Martz, Karen; Harper, Barrie; Kearns, Gregory L.; Capparelli, Edmund V.; Siegel, David; Benjamin, Daniel K.; Smith, P. Brian</p> <p>2013-01-01</p> <p>Background Limited pharmacokinetic (PK) data of metronidazole in premature infants has led to various dosing recommendations. Surrogate efficacy targets for metronidazole are ill-defined and therefore aimed to exceed minimum inhibitory concentration of organisms responsible for intra-abdominal infections. Methods We evaluated the PK of metronidazole using plasma and dried blood spot (DBS) samples from infants ≤32 weeks gestational age in an open-label, PK, multicenter (N=3) study using population PK modeling (NONMEM). Monte Carlo simulations (N=1000 virtual subjects) were used to evaluate the surrogate efficacy target. Metabolic ratios of parent and metabolite were calculated. Results Twenty-four premature infants (111 plasma and 51 DBS samples) were enrolled: median (range) gestational age at birth 25 (23–31) weeks, postnatal age 27 (1–82) days, postmenstrual age (PMA) 31 (24–39) weeks, and weight 740 (431–1466) g. Population clearance (CL, L/h/kg) was 0.038 × (PMA/30)2.45 and volume of distribution (L/kg) of 0.93. PK parameter estimates and precision were similar between plasma and DBS samples. Metabolic ratios correlated with CL. Conclusion Simulations suggested the majority of infants in the neonatal intensive care unit (>80%) would meet the surrogate efficacy target using PMA-based dosing. PMID:23587979</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://pubs.water.usgs.gov/wri97-4225/','USGSPUBS'); return false;" href="http://pubs.water.usgs.gov/wri97-4225/"><span>Preliminary estimates of residence times and apparent ages of ground water in the Chesapeake Bay watershed, and water-quality data from a survey of springs</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Focazio, Michael J.; Plummer, Niel; Bohlke, John K.; Busenberg, Eurybiades; Bachman, L. Joseph; Powars, David S.</p> <p>1998-01-01</p> <p>Knowledge of the residence times of the ground-water systems in Chesapeake Bay watershed helps resource managers anticipate potential delays between implementation of land-management practices and any improve-ments in river and estuary water quality. This report presents preliminary estimates of ground-water residence times and apparent ages of water in the shallow aquifers of the Chesapeake Bay watershed. A simple reservoir model, published data, and analyses of spring water were used to estimate residence times and apparent ages of ground-water discharge. Ranges of aquifer hydraulic characteristics throughout the Bay watershed were derived from published literature and were used to estimate ground-water residence times on the basis of a simple reservoir model. Simple combinations of rock type and physiographic province were used to delineate hydrogeomorphic regions (HGMR?s) for the study area. The HGMR?s are used to facilitate organization and display of the data and analyses. Illustrations depicting the relation of aquifer characteristics and associated residence times as a continuum for each HGMR were developed. In this way, the natural variation of aquifer characteristics can be seen graphically by use of data from selected representative studies. Water samples collected in September and November 1996, from 46 springs throughout the watershed were analyzed for chlorofluorocarbons (CFC?s) to estimate the apparent age of ground water. For comparison purposes, apparent ages of water from springs were calculated assuming piston flow. Additi-onal data are given to estimate apparent ages assuming an exponential distribution of ages in spring discharge. Additionally, results from previous studies of CFC-dating of ground water from other springs and wells in the watershed were compiled. The CFC data, and the data on major ions, nutrients, and nitrogen isotopes in the water collected from the 46 springs are included in this report. The apparent ages of water discharging from 30 of the 46 springs sampled were less than 20 years, including 5 that were 'modern' (0-4 years). Four samples had apparent ages of 22 to 34 years, and two others from thermal springs were 40 years or greater. The remaining ten samples were contaminated with local sources of CFC and could not be dated. Nitrate concentrations and nitrate delta 15 nitrogen (15N) values in water from many springs are similar to those in shallow ground water beneath fertilized fields, and some values are high enough to indicate a probable source from animal-waste components. The nitrogen data reported here highlight the significance of the springs sampled during this study as pathways for nutrient transport in the Chesapeake Bay watershed. Ground-water samples were collected from springs during an unusually high flow period and thus may not be representative of low base-flow conditions. Residence times estimated from plausible ranges of aquifer properties and results of previous age-dating analyses generally corroborate the apparent-age analysis made in the current study and suggests that some residence times could be much longer. The shortest residence times tend to be in the Blue Ridge and northern carbonate areas; however, the data are preliminary and not appropriate for statistical tests of significance or variance. Because the age distributions in the aquifer discharging to the springs are not known, and because the apparent ages of water from the springs are based on various com-binations of CFC criteria, the apparent ages and calculated residence times are compared for illustrative purposes but are considered preliminary until further work is accomplished.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27479945','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27479945"><span>Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Horvath, Steve; Langfelder, Peter; Kwak, Seung; Aaronson, Jeff; Rosinski, Jim; Vogt, Thomas F; Eszes, Marika; Faull, Richard L M; Curtis, Maurice A; Waldvogel, Henry J; Choi, Oi-Wa; Tung, Spencer; Vinters, Harry V; Coppola, Giovanni; Yang, X William</p> <p>2016-07-01</p> <p>Age of Huntington's disease (HD) motoric onset is strongly related to the number of CAG trinucleotide repeats in the huntingtin gene, suggesting that biological tissue age plays an important role in disease etiology. Recently, a DNA methylation based biomarker of tissue age has been advanced as an epigenetic aging clock. We sought to inquire if HD is associated with an accelerated epigenetic age. DNA methylation data was generated for 475 brain samples from various brain regions of 26 HD cases and 39 controls. Overall, brain regions from HD cases exhibit a significant epigenetic age acceleration effect (p=0.0012). A multivariate model analysis suggests that HD status increases biological age by 3.2 years. Accelerated epigenetic age can be observed in specific brain regions (frontal lobe, parietal lobe, and cingulate gyrus). After excluding controls, we observe a negative correlation (r=-0.41, p=5.5×10-8) between HD gene CAG repeat length and the epigenetic age of HD brain samples. Using correlation network analysis, we identify 11 co-methylation modules with a significant association with HD status across 3 broad cortical regions. In conclusion, HD is associated with an accelerated epigenetic age of specific brain regions and more broadly with substantial changes in brain methylation levels.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4993344','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4993344"><span>Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Horvath, Steve; Langfelder, Peter; Kwak, Seung; Aaronson, Jeff; Rosinski, Jim; Vogt, Thomas F.; Eszes, Marika; Faull, Richard L.M.; Curtis, Maurice A.; Waldvogel, Henry J.; Choi, Oi-Wa; Tung, Spencer; Vinters, Harry V.; Coppola, Giovanni; Yang, X. William</p> <p>2016-01-01</p> <p>Age of Huntington's disease (HD) motoric onset is strongly related to the number of CAG trinucleotide repeats in the huntingtin gene, suggesting that biological tissue age plays an important role in disease etiology. Recently, a DNA methylation based biomarker of tissue age has been advanced as an epigenetic aging clock. We sought to inquire if HD is associated with an accelerated epigenetic age. DNA methylation data was generated for 475 brain samples from various brain regions of 26 HD cases and 39 controls. Overall, brain regions from HD cases exhibit a significant epigenetic age acceleration effect (p=0.0012). A multivariate model analysis suggests that HD status increases biological age by 3.2 years. Accelerated epigenetic age can be observed in specific brain regions (frontal lobe, parietal lobe, and cingulate gyrus). After excluding controls, we observe a negative correlation (r=−0.41, p=5.5×10−8) between HD gene CAG repeat length and the epigenetic age of HD brain samples. Using correlation network analysis, we identify 11 co-methylation modules with a significant association with HD status across 3 broad cortical regions. In conclusion, HD is associated with an accelerated epigenetic age of specific brain regions and more broadly with substantial changes in brain methylation levels. PMID:27479945</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018ACP....18.4981G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018ACP....18.4981G"><span>Concentrations and source regions of light-absorbing particles in snow/ice in northern Pakistan and their impact on snow albedo</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Gul, Chaman; Praveen Puppala, Siva; Kang, Shichang; Adhikary, Bhupesh; Zhang, Yulan; Ali, Shaukat; Li, Yang; Li, Xiaofei</p> <p>2018-04-01</p> <p>Black carbon (BC), water-insoluble organic carbon (OC), and mineral dust are important particles in snow and ice which significantly reduce albedo and accelerate melting. Surface snow and ice samples were collected from the Karakoram-Himalayan region of northern Pakistan during 2015 and 2016 in summer (six glaciers), autumn (two glaciers), and winter (six mountain valleys). The average BC concentration overall was 2130 ± 1560 ng g-1 in summer samples, 2883 ± 3439 ng g-1 in autumn samples, and 992 ± 883 ng g-1 in winter samples. The average water-insoluble OC concentration overall was 1839 ± 1108 ng g-1 in summer samples, 1423 ± 208 ng g-1 in autumn samples, and 1342 ± 672 ng g-1 in winter samples. The overall concentration of BC, OC, and dust in aged snow samples collected during the summer campaign was higher than the concentration in ice samples. The values are relatively high compared to reports by others for the Himalayas and the Tibetan Plateau. This is probably the result of taking more representative samples at lower elevation where deposition is higher and the effects of ageing and enrichment are more marked. A reduction in snow albedo of 0.1-8.3 % for fresh snow and 0.9-32.5 % for aged snow was calculated for selected solar zenith angles during daytime using the Snow, Ice, and Aerosol Radiation (SNICAR) model. The daily mean albedo was reduced by 0.07-12.0 %. The calculated radiative forcing ranged from 0.16 to 43.45 W m-2 depending on snow type, solar zenith angle, and location. The potential source regions of the deposited pollutants were identified using spatial variance in wind vector maps, emission inventories coupled with backward air trajectories, and simple region-tagged chemical transport modeling. Central, south, and west Asia were the major sources of pollutants during the sampling months, with only a small contribution from east Asia. Analysis based on the Weather Research and Forecasting (WRF-STEM) chemical transport model identified a significant contribution (more than 70 %) from south Asia at selected sites. Research into the presence and effect of pollutants in the glaciated areas of Pakistan is economically significant because the surface water resources in the country mainly depend on the rivers (the Indus and its tributaries) that flow from this glaciated area.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29384741','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29384741"><span>A radiographic study of the mandibular third molar root development in different ethnic groups.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Liversidge, H M; Peariasamy, K; Folayan, M O; Adeniyi, A O; Ngom, P I; Mikami, Y; Shimada, Y; Kuroe, K; Tvete, I F; Kvaal, S I</p> <p>2017-12-01</p> <p>The nature of differences in the timing of tooth formation between ethnic groups is important when estimating age. To calculate age of transition of the mandibular third (M3) molar tooth stages from archived dental radiographs from sub-Saharan Africa, Malaysia, Japan and two groups from London UK (Whites and Bangladeshi). The number of radiographs was 4555 (2028 males, 2527 females) with an age range 10-25 years. The left M3 was staged into Moorrees stages. A probit model was fitted to calculate mean ages for transitions between stages for males and females and each ethnic group separately. The estimated age distributions given each M3 stage was calculated. To assess differences in timing of M3 between ethnic groups, three models were proposed: a separate model for each ethnic group, a joint model and a third model combining some aspects across groups. The best model fit was tested using Bayesian and Akaikes information criteria (BIC and AIC) and log likelihood ratio test. Differences in mean ages of M3 root stages were found between ethnic groups, however all groups showed large standard deviation values. The AIC and log likelihood ratio test indicated that a separate model for each ethnic group was best. Small differences were also noted between timing of M3 between males and females, with the exception of the Malaysian group. These findings suggests that features of a reference data set (wide age range and uniform age distribution) and a Bayesian statistical approach are more important than population specific convenience samples to estimate age of an individual using M3. Some group differences were evident in M3 timing, however, this has some impact on the confidence interval of estimated age in females and little impact in males because of the large variation in age.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3758911','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3758911"><span>Integrating Prospective Longitudinal Data: Modeling Personality and Health in the Terman Life Cycle and Hawaii Longitudinal Studies</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Kern, Margaret L.; Hampson, Sarah E.; Goldberg, Lewis R.; Friedman, Howard S.</p> <p>2013-01-01</p> <p>The present study used a collaborative framework to integrate two long-term prospective studies: the Terman Life Cycle Study and the Hawaii Personality and Health Longitudinal Study. Using a five-factor personality-trait framework, teacher assessments of child personality were rationally and empirically aligned to establish similar factor structures across samples. Comparable items related to adult self-rated health, education, and alcohol use were harmonized, and data were pooled on harmonized items. A structural model was estimated, allowing paths to differ by sample. Harmonized child personality factors were then used to examine markers of physiological dysfunction in the Hawaii sample and mortality risk in the Terman sample. Harmonized conscientiousness predicted less physiological dysfunction in the Hawaii sample and lower mortality risk in the Terman sample. These results illustrate how collaborative, integrative work with multiple samples offers the exciting possibility that samples from different cohorts and ages can be linked together to directly test lifespan theories of personality and health. PMID:23231689</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28854613','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28854613"><span>Racial/Ethnic Differences in Expectations Regarding Aging Among Older Adults.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Menkin, Josephine A; Guan, Shu-Sha Angie; Araiza, Daniel; Reyes, Carmen E; Trejo, Laura; Choi, Sarah E; Willis, Phyllis; Kotick, John; Jimenez, Elizabeth; Ma, Sina; McCreath, Heather E; Chang, Emiley; Witarama, Tuff; Sarkisian, Catherine A</p> <p>2017-08-01</p> <p>The study identifies differences in age-expectations between older adults from Korean, Chinese, Latino, and African American backgrounds living in the United States. This study uses baseline demographic, age-expectation, social, and health data from 229 racial/ethnic minority seniors in a stroke-prevention intervention trial. Unadjusted regression models and pair-wise comparisons tested for racial/ethnic differences in age-expectations, overall, and across domain subscales (e.g., physical-health expectations). Adjusted regression models tested whether age-expectations differed across racial/ethnic groups after controlling for demographic, social, and health variables. Regression and negative binomial models tested whether age-expectations were consistently associated with health and well-being across racial/ethnic groups. Age-expectations differed by race/ethnicity, overall and for each subscale. African American participants expected the least age-related functional decline and Chinese American participants expected the most decline. Although African American participants expected less decline than Latino participants in unadjusted models, they had comparable expectations adjusting for education. Latino and African American participants consistently expected less decline than Korean and Chinese Americans. Acculturation was not consistently related to age-expectations among immigrant participants over and above ethnicity. Although some previously observed links between expectations and health replicated across racial/ethnic groups, in adjusted models age-expectations were only related to depression for Latino participants. With a growing racial/ethnic minority older population in the United States, it is important to note older adults' age-expectations differ by race/ethnicity. Moreover, expectation-health associations may not always generalize across diverse samples. © The Author 2017. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3339463','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3339463"><span>Understanding Differences in the Body Burden–Age Relationships of Bioaccumulating Contaminants Based on Population Cross Sections versus Individuals</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Quinn, Cristina L.</p> <p>2012-01-01</p> <p>Background: Body burdens of persistent bioaccumulative contaminants estimated from the cross-sectional biomonitoring of human populations are often plotted against age. Such relationships have previously been assumed to reflect the role of age in bioaccumulation. Objectives: We used a mechanistic modeling approach to reproduce concentration-versus-age relationships and investigate factors that influence them. Method: CoZMoMAN is an environmental fate and human food chain bioaccumulation model that estimates time trends in human body burdens in response to time-variant environmental emissions. Trends of polychlorinated biphenyl (PCB) congener 153 concentrations versus age for population cross sections were estimated using simulated longitudinal data for individual women born at different times. The model was also used to probe the influence of partitioning and degradation properties, length of emissions, and model assumptions regarding lipid content and liver metabolism on concentration–age trends of bioaccumulative and persistent contaminants. Results: Body burden–age relationships for population cross sections and individuals over time are not equivalent. The time lapse between the peak in emissions and sample collection for biomonitoring is the most influential factor controlling the shape of concentration–age trends for chemicals with human metabolic half-lives longer than 1 year. Differences in observed concentration–age trends for PCBs and polybrominated diphenyl ethers are consistent with differences in emission time trends and human metabolic half-lives. Conclusions: Bioaccumulation does not monotonically increase with age. Our model suggests that the main predictors of cross-sectional body burden trends with age are the amount of time elapsed after peak emissions and the human metabolic and environmental degradation rates. PMID:22472302</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26890690','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26890690"><span>How age and gender predict illness course in a first-episode nonaffective psychosis cohort.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Drake, Richard J; Addington, Jean; Viswanathan, Ananth C; Lewis, Shôn W; Cotter, Jack; Yung, Alison R; Abel, Kathryn M</p> <p>2016-03-01</p> <p>Male gender and young age at onset of schizophrenia are traditionally associated with poor treatment outcome and often used to determine prognosis. However, many studies use nonincident samples and fail to adjust for symptom severity at onset. We hypothesized that age and gender would influence severity of presentation but would not predict outcome after adjustment for symptoms at presentation. 628 people with first-episode ICD-9 and DSM-IV nonaffective psychosis from 2 historical cohorts recruited from sequential presentations in Canada and the United Kingdom (1996-1998) were assessed prospectively at presentation and over 12-18 months using the Positive and Negative Syndrome Scale (PANSS). Models of the age-at-onset distributions with 2 underlying modes at similar ages in women (ages 23 years and 47 years) and men (ages 22 years and 46 years) had relatively good fits compared to single-mode models (χ(2)1 better by 9.2 for females, 8.0 for males, both P < .05). At presentation, scores for negative symptoms were 1.84 points worse for males (95% CI, 1.05 to 2.58; P < .001) in a mixed effects model. Younger age also predicted higher negative scores at presentation (partial correlation r = -0.18, P < .01; P < .001 in the mixed effects model). Findings were similar for cognitive-disorganized symptoms. However, after controlling for baseline symptoms, age at onset and gender did not significantly predict subsequent symptom course in the mixed effects models. Gender and age at onset are independently associated with symptoms at presentation but not with medium-term course of schizophrenia. This finding reinforces the importance of early identification and prevention of severe negative symptoms at first episode, whatever an individual's age and gender. © Copyright 2016 Physicians Postgraduate Press, Inc.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15260873','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15260873"><span>Factor structure of the pictorial scale of perceived competence and social acceptance with two pre-elementary samples.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Mantzicopoulos, Panayota; French, Brian F; Maller, Susan J</p> <p>2004-01-01</p> <p>Competing models of the factorial structure of the Pictorial Scale of Perceived Competence and Social Acceptance (PSPCSA) were tested for fit using multisample confirmatory factor analysis. The best fitting model was tested for invariance (a) across samples of middle-class (n = 251) and economically disadvantaged (Head Start, n = 117) kindergarten children (whose ages ranged from 67 to 86 months), and (b) over time (at the end of preschool and kindergarten) for the Head Start sample. For kindergarten children, regardless of socioeconomic status, the factor structure of the PSPCSA was consistent with the 2-factor model of Competence and Acceptance. This model also fit reasonably well for Head Start children at the end of their preschool year. However, in addition to providing broad support for the dimensionality of the measure, our findings highlight important concerns about the PSPCSA. Copyright 2004 Society for Research in Child Development, Inc.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15724168','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15724168"><span>Near-infrared spectroscopic observation of the ageing process in archaeological wood using a deuterium exchange method.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Tsuchikawa, Satoru; Yonenobu, Hitoshi; Siesler, H W</p> <p>2005-03-01</p> <p>The ageing degradation of the fine wood structure of dry-exposed archaeological wood was investigated by Fourier transform near-infrared spectroscopy with the aid of a deuterium exchange method. The archaeological wood sample was taken from an old wooden temple in Japan (late 7th century), which has been designated as a UNESCO world heritage site. Comparing the analytical results with those of a modern wood sample of the same species, the ageing process of archaeological wood was clarified as a change in the state of order on a macromolecular structural level. It can be concluded from NIR spectra that the amorphous region, and partially semi-crystalline region, in cellulose, hemicellulose, and lignin decreased by the ageing degradation, whereas the crystalline region in cellulose was not affected by the ageing. The accessibility of the diffusant to effect H/D-exchange was monitored by an OH-related absorption band obtained from FT-NIR transmission spectroscopy and characteristically varied with the ageing process of the wood samples, the absorption bands characteristic of a specific state of order and the diffusion agent. Finally, we proposed a morphological model to describe the variation of the fine structure of the microfibrils in the cell wall with ageing degradation. The state of microfibrils changed loosely by ageing, so that elementary fibrils were arranged loosely under 5 A, whereas several elementary fibrils in the modern wood were arranged in very close proximity under 3 A to each other.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22050770','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22050770"><span>Developing a dimensional model for successful cognitive and emotional aging.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Vahia, Ipsit V; Thompson, Wesley K; Depp, Colin A; Allison, Matthew; Jeste, Dilip V</p> <p>2012-04-01</p> <p>There is currently a lack of consensus on the definition of successful aging (SA) and existing implementations have omitted constructs associated with SA. We used empirical methods to develop a dimensional model of SA that incorporates a wider range of associated variables, and we examined the relationship among these components using factor analysis and Bayesian Belief Nets. We administered a successful aging questionnaire comprising several standardized measures related to SA to a sample of 1948 older women enrolled in the San Diego site of the Women's Health Initiative study. The SA-related variables we included in the model were self-rated successful aging, depression severity, physical and emotional functioning, optimism, resilience, attitude towards own aging, self-efficacy, and cognitive ability. After adjusting for age, education and income, we fitted an exploratory factor analysis model to the SA-related variables and then, in order to address relationships among these factors, we computed a Bayesian Belief Net (BBN) using rotated factor scores. The SA-related variables loaded onto five factors. Based on the loading, we labeled the factors as follows: self-rated successful aging, cognition, psychosocial protective factors, physical functioning, and emotional functioning. In the BBN, self-rated successful aging emerged as the primary downstream factor and exhibited significant partial correlations with psychosocial protective factors, physical/general status and mental/emotional status but not with cognitive ability. Our study represents a step forward in developing a dimensional model of SA. Our findings also point to a potential role for psychiatry in improving successful aging by managing depressive symptoms and developing psychosocial interventions to improve self-efficacy, resilience, and optimism.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=%22facial+recognition%22&pg=6&id=EJ850208','ERIC'); return false;" href="https://eric.ed.gov/?q=%22facial+recognition%22&pg=6&id=EJ850208"><span>A Longitudinal Investigation of Visual Event-Related Potentials in the First Year of Life</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Webb, Sara J.; Long, Jeffrey D.; Nelson, Charles A.</p> <p>2005-01-01</p> <p>The goal of the current study was to assess general maturational changes in the ERP in the same sample of infants from 4 to 12 months of age. All participants were tested in two experimental manipulations at each age: a test of facial recognition and one of object recognition. Two sets of analyses were undertaken. First, growth curve modeling with…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=social+AND+stress&pg=6&id=EJ973276','ERIC'); return false;" href="https://eric.ed.gov/?q=social+AND+stress&pg=6&id=EJ973276"><span>Daily Social Exchanges and Affect in Middle and Later Adulthood: The Impact of Loneliness and Age</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Russell, Alissa; Bergeman, C. S.; Scott, Stacey B.</p> <p>2012-01-01</p> <p>Although daily social exchanges are important for well-being, it is unclear how different types of exchanges affect daily well-being, as well as which factors influence the way in which individuals react to their daily social encounters. The present study included a sample of 705 adults aged 31 to 91, and using Multilevel Modeling analyses…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=growth+AND+child+AND+3+AND+years&pg=6&id=EJ1056678','ERIC'); return false;" href="https://eric.ed.gov/?q=growth+AND+child+AND+3+AND+years&pg=6&id=EJ1056678"><span>Teacher Network of Relationships Inventory: Measurement Invariance of Academically At-Risk Students across Ages 6 to 15</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Wu, Jiun-Yu; Hughes, Jan N.</p> <p>2015-01-01</p> <p>We tested the longitudinal measurement invariance of the Teacher Network of Relationships Inventory (TNRI), a teacher-report measure of teacher-student relationship quality (TSRQ), on a sample of 784 academically at-risk students across ages 6 to 15 years by comparing the model for each subsequent year with that of the previous year(s). The TNRI…</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li class="active"><span>21</span></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_21 --> <div id="page_22" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li class="active"><span>22</span></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="421"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=relationship+AND+self-esteem+AND+self+AND+identity&pg=6&id=EJ698227','ERIC'); return false;" href="https://eric.ed.gov/?q=relationship+AND+self-esteem+AND+self+AND+identity&pg=6&id=EJ698227"><span>Ethnic Identity, Self-Esteem, and Perceived Efficacy as Mediators of the Relation of Supportive Parenting to Psychosocial Outcomes among Urban Adolescents</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Swenson, R.R.; Prelow, H.M.</p> <p>2005-01-01</p> <p>The present study examined the direct and indirect relationships among supportive parenting, ethnic identity, self-esteem, perceived efficacy, and psychological adjustment in an urban sample of 133 African American (M age=16.37) and 110 European American (M age=16.43) adolescents. Although the mediational model was partially supported for both…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=impacts+AND+delinquency+AND+community&pg=7&id=ED239188','ERIC'); return false;" href="https://eric.ed.gov/?q=impacts+AND+delinquency+AND+community&pg=7&id=ED239188"><span>Predicting Gang Fight Participation in a General Youth Sample via the HEW Youth Development Model's Community Program Impact Scales, Age, and Sex.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Truckenmiller, James L.</p> <p></p> <p>The accurate prediction of violence has been in the spotlight of critical concern in recent years. To investigate the relative predictive power of peer pressure, youth perceived negative labeling, youth perceived access to educational and occupational roles, social alienation, self-esteem, sex, and age with regard to gang fight participation…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ794139.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ794139.pdf"><span>Physical Activity Patterns During School Recess: A Study in Children 6 to 10 Years Old</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Lopes, Victor; Vasques, Catarina Margarida Silva; de Oliveira Pereira, Maria Beatriz Ferreira Leite</p> <p>2006-01-01</p> <p>The aims of this study were to characterize the spontaneous physical activity of children during school recess, and to estimate variation in physical activity associated with gender and age. A MTI actigraph (Model 7164) was used with a sample of 140 boys and 131 girls, 6 to 10 years of age. MTI counts were converted to METs using a regression…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=community+AND+violence&pg=5&id=EJ865766','ERIC'); return false;" href="https://eric.ed.gov/?q=community+AND+violence&pg=5&id=EJ865766"><span>The Effects of Community and Family Violence Exposure on Anxiety Trajectories during Middle Childhood: The Role of Family Social Support as a Moderator</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Kennedy, Angie C.; Bybee, Deborah; Sullivan, Cris M.; Greeson, Megan</p> <p>2009-01-01</p> <p>This 2-year longitudinal study investigated the relations between community and school violence exposure, witnessing intimate partner violence (IPV), family social support, and anxiety, within a sample of 100 school-age children (39% female, M age = 9.90 years). Using multilevel modeling, we found heterogeneity across children in terms of their…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27757575','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27757575"><span>New models for age estimation and assessment of their accuracy using developing mandibular third molar teeth in a Thai population.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Duangto, P; Iamaroon, A; Prasitwattanaseree, S; Mahakkanukrauh, P; Janhom, A</p> <p>2017-03-01</p> <p>Age estimation using developing third molar teeth is considered an important and accurate technique for both clinical and forensic practices. The aims of this study were to establish population-specific reference data, to develop age prediction models using mandibular third molar development, to test the accuracy of the resulting models, and to find the probability of persons being at the age thresholds of legal relevance in a Thai population. A total of 1867 digital panoramic radiographs of Thai individuals aged between 8 and 23 years was selected to assess dental age. The mandibular third molar development was divided into nine stages. The stages were evaluated and each stage was transformed into a development score. Quadratic regression was employed to develop age prediction models. Our results show that males reached mandibular third molar root formation stages earlier than females. The models revealed a high correlation coefficient for both left and right mandibular third molar teeth in both sexes (R = 0.945 and 0.944 in males, R = 0.922 and 0.923 in females, respectively). Furthermore, the accuracy of the resulting models was tested in randomly selected 374 cases and showed low error values between the predicted dental age and the chronological age for both left and right mandibular third molar teeth in both sexes (-0.13 and -0.17 years in males, 0.01 and 0.03 years in females, respectively). In Thai samples, when the mandibular third molar teeth reached stage H, the probability of the person being over 18 years was 100 % in both sexes.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3681863','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3681863"><span>Immunization of Aged Pigs with Attenuated Pseudorabies Virus Vaccine Combined with CpG Oligodeoxynucleotide Restores Defective Th1 Immune Responses</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Chu, Pinpin; Ma, Miaopeng; Shi, Juqing; Cai, Haiming; Huang, Chaoyuan; Li, Huazhou; Jiang, Zhenggu; Wang, Houguang; Wang, Weifang; Zhang, Shuiqing; Zhang, Linghua</p> <p>2013-01-01</p> <p>Background and Aims Attempts to immunize aged subjects often result in the failure to elicit a protective immune response. Murine model studies have shown that oligonucleotides containing CpG motifs (CpG ODN) can stimulate immune system in aged mice as effectively as in young mice. Since many physiological and pathophysiological data of pigs can be transferred to humans, research in pigs is important to confirm murine data. Here we investigated whether immunization of aged pig model with attenuated pseudorabies virus vaccine (PRV vaccine) formulated with CpG ODN could promote a successful development of immune responses that were comparable to those induced in young pigs in a similar manner. Methodology Young and aged pigs were immunized IM with PRV vaccine alone, or in combination with CpG ODN respectively. At days 3, 7, 14 post immunization sera were assayed by ELISA for IgG titres, at day 7 for IgG1 and IgG2 subtypes titres. All blood samples collected in evacuated test tubes with K-EDTA at day 7 were analyzed for flow cytometer assay. Blood samples at day 7 collected in evacuated test tubes with heparin were analysed for antigen-specific cytokines production and peripheral blood mononuclear cells (PBMCs) proliferative responses. Results CpG ODN could enhance Th1 responses (PRV-specific IgG2/IgG1 ratio, proliferative responses, Th1 cytokines production) when used as an adjuvant for the vaccination of aged pigs, which were correlated with enhanced CD4+ T cells percentage, decreased CD4+CD8+CD45RO+ T cells percentage and improved PRV-specific CD4+ T cells activation. Conclusions Our results demonstrate a utility for CpG ODN, as a safe vaccine adjuvant for promoting effective systemic immune responses in aged pig model. This agent could have important clinical uses in overcoming some of age-associated depressions in immune function that occur in response to vaccination. PMID:23785433</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28432824','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28432824"><span>An analysis of dental development in Pleistocene Homo using skeletal growth and chronological age.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Šešelj, Maja</p> <p>2017-07-01</p> <p>This study takes a new approach to interpreting dental development in Pleistocene Homo in comparison with recent modern humans. As rates of dental development and skeletal growth are correlated given age in modern humans, using age and skeletal growth in tandem yields more accurate dental development estimates. Here, I apply these models to fossil Homo to obtain more individualized predictions and interpretations of their dental development relative to recent modern humans. Proportional odds logistic regression models based on three recent modern human samples (N = 181) were used to predict permanent mandibular tooth development scores in five Pleistocene subadults: Homo erectus/ergaster, Neanderthals, and anatomically modern humans (AMHs). Explanatory variables include a skeletal growth indicator (i.e., diaphyseal femoral length), and chronological age. AMHs Lagar Velho 1 and Qafzeh 10 share delayed incisor development, but exhibit considerable idiosyncratic variation within and across tooth types, relative to each other and to the reference samples. Neanderthals Dederiyeh 1 and Le Moustier 1 exhibit delayed incisor coupled with advanced molar development, but differences are reduced when femoral diaphysis length is considered. Dental development in KNM-WT 15,000 Homo erectus/ergaster, while advanced for his age, almost exactly matches the predictions once femoral length is included in the models. This study provides a new interpretation of dental development in KNM-WT 15000 as primarily reflecting his faster rates of skeletal growth. While the two AMH specimens exhibit considerable individual variation, the Neanderthals exhibit delayed incisor development early and advanced molar development later in ontogeny. © 2017 Wiley Periodicals, Inc.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4295891','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4295891"><span>Interaction between Helicobacter pylori and Latent Toxoplasmosis and Demographic Variables on Cognitive Function in Young to Middle-Aged Adults</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Gale, Shawn D.; Erickson, Lance D.; Brown, Bruce L.; Hedges, Dawson W.</p> <p>2015-01-01</p> <p>Helicobacter pylori and latent toxoplasmosis are widespread diseases that have been associated with cognitive deficits and Alzheimer’s disease. We sought to determine whether interactions between Helicobacter pylori and latent toxoplasmosis, age, race-ethnicity, educational attainment, economic status, and general health predict cognitive function in young and middle-aged adults. To do so, we used multivariable regression and multivariate models to analyze data obtained from the United States’ National Health and Nutrition Examination Survey from the Centers for Disease Control and Prevention, which can be weighted to represent the US population. In this sample, we found that 31.6 percent of women and 36.2 percent of men of the overall sample had IgG Antibodies against Helicobacter pylori, although the seroprevalence of Helicobacter pylori varied with sociodemographic variables. There were no main effects for Helicobacter pylori or latent toxoplasmosis for any of the cognitive measures in models adjusting for age, sex, race-ethnicity, educational attainment, economic standing, and self-rated health predicting cognitive function. However, interactions between Helicobacter pylori and race-ethnicity, educational attainment, latent toxoplasmosis in the fully adjusted models predicted cognitive function. People seropositive for both Helicobacter pylori and latent toxoplasmosis – both of which appear to be common in the general population – appear to be more susceptible to cognitive deficits than are people seropositive for either Helicobacter pylori and or latent toxoplasmosis alone, suggesting a synergistic effect between these two infectious diseases on cognition in young to middle-aged adults. PMID:25590622</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26917166','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26917166"><span>Accelerated Brain Aging in Schizophrenia: A Longitudinal Pattern Recognition Study.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Schnack, Hugo G; van Haren, Neeltje E M; Nieuwenhuis, Mireille; Hulshoff Pol, Hilleke E; Cahn, Wiepke; Kahn, René S</p> <p>2016-06-01</p> <p>Despite the multitude of longitudinal neuroimaging studies that have been published, a basic question on the progressive brain loss in schizophrenia remains unaddressed: Does it reflect accelerated aging of the brain, or is it caused by a fundamentally different process? The authors used support vector regression, a supervised machine learning technique, to address this question. In a longitudinal sample of 341 schizophrenia patients and 386 healthy subjects with one or more structural MRI scans (1,197 in total), machine learning algorithms were used to build models to predict the age of the brain and the presence of schizophrenia ("schizophrenia score"), based on the gray matter density maps. Age at baseline ranged from 16 to 67 years, and follow-up scans were acquired between 1 and 13 years after the baseline scan. Differences between brain age and chronological age ("brain age gap") and between schizophrenia score and healthy reference score ("schizophrenia gap") were calculated. Accelerated brain aging was calculated from changes in brain age gap between two consecutive measurements. The age prediction model was validated in an independent sample. In schizophrenia patients, brain age was significantly greater than chronological age at baseline (+3.36 years) and progressively increased during follow-up (+1.24 years in addition to the baseline gap). The acceleration of brain aging was not constant: it decreased from 2.5 years/year just after illness onset to about the normal rate (1 year/year) approximately 5 years after illness onset. The schizophrenia gap also increased during follow-up, but more pronounced variability in brain abnormalities at follow-up rendered this increase nonsignificant. The progressive brain loss in schizophrenia appears to reflect two different processes: one relatively homogeneous, reflecting accelerated aging of the brain and related to various measures of outcome, and a more variable one, possibly reflecting individual variation and medication use. Differentiating between these two processes may not only elucidate the various factors influencing brain loss in schizophrenia, but also assist in individualizing treatment.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2002AGUFM.T62A1284U','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2002AGUFM.T62A1284U"><span>Reconsideration of evolutionary model of the Hawaiian-type volcano: 40Ar/39Ar ages for lavas from deep interior of Oahu Island and alkali basalts from the North Arch volcanic field</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Uto, K.; Ishizuka, O.; Garcia, M. O.; Clague, D. A.; Naka, J.</p> <p>2002-12-01</p> <p>Growth history of Hawaiian-type volcanoes is typified into four stages: pre-shield, shield-forming, post-shield and rejuvinated. Duration of volcanism from pre-shield to post-shield stage is considered to be at most two million years, and is followed by the rejuvinated-stage after the dormance of one to two million years. There are, however, considerable amount of volcanic products hidden beneath the surface, and the above model may not be real due to the limited observation. US-Japan joint research on Hawaiian volcanism using ROV {\\KAIKO} and submersible {\\SHINKAI6500} of JAMSTEC has revealed many unknown volcanic processes of Hawaii. We challenge the well-established growth model of Hawaiian volcanoes from 40Ar/39Ar dating on rocks collected from the deep root of the submarine cliff of Oahu Island and from the widespread lava field off the coast of Oahu. Northern slope of Oahu Island is a deeply dissected steep wall from the ridge 1,000 m above the sea level to 3,000 m beneath the sea level. We expected to discover the deeper part of volcanic products forming Oahu Island. We obtained 6 40Ar/39Ar ages for tholeiitic lavas collected from 3,000 m to 2,600 m below the sea level. Ages are 5.7 and 6 Ma for two samples from the depth of 2,800 - 3,000 m, 4 Ma for a sample from 2,630 m, 3 Ma for a rock dredged between 2,500 and 2,800m, and 2.2 Ma for a sample from 2,602 m. Ages between 2.2 and 4 Ma are compatible with existing ages on subaerial shield-forming lavas on Koolau and Waianae volcano on Oahu, but ages of 5.7 and 6 Ma are about two million years older. Duplicate analyses gave concordant results and isochron ages have atmospheric 40Ar/36Ar initials. We, therefore, consider that these ages represent eruptive ages of samples. Current results suggest that tholeiitic volcanism forming Oahu Island continued almost 4 million years, which is far longer than ever considered. Considering the 8.7 cm/y of plate velocity, volcanism continued while Oahu Island moved 350 km from the place it was born. This may suggest the dimension of Hawaiian plume if it had been fixed to the earth, or may indicate the some temporal swing of the plume. North Arch volcanic field is a wide-spread flat lava flow field of extremely silica undersaturated alkali basalts existing about 200 km north from the Hawaiian volcanic chain. Six lavas taken by {\\SHINKAI6500} and four samples dredged by USGS are dated. Ages are continuously ranging from 1.4 to 0.5 Ma, suggesting that the volcanism continued at least one million years contemporaneously with rejuvinated-stage volcanism on the islands of Oahu, Niihau, Kauai and Molokai. Chemical compositions of North-Arch lavas are within the variation of these rejuvinated-stage alkali basalts. The similarities in ages and chemistry question the origin of rejuvinated-stage volcanism. These lavas may not be peripheral products of Hawaiian plume, but represent marginal volcanoes of much larger North Arch volcanic field.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017PhDT........51E','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017PhDT........51E"><span>Phenomenological Modeling and Laboratory Simulation of Long-Term Aging of Asphalt Mixtures</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Elwardany, Michael Dawoud</p> <p></p> <p>The accurate characterization of asphalt mixture properties as a function of pavement service life is becoming more important as more powerful pavement design and performance prediction methods are implemented. Oxidative aging is a major distress mechanism of asphalt pavements. Aging increases the stiffness and brittleness of the material, which leads to a high cracking potential. Thus, an improved understanding of the aging phenomenon and its effect on asphalt binder chemical and rheological properties will allow for the prediction of mixture properties as a function of pavement service life. Many researchers have conducted laboratory binder thin-film aging studies; however, this approach does not allow for studying the physicochemical effects of mineral fillers on age hardening rates in asphalt mixtures. Moreover, aging phenomenon in the field is governed by kinetics of binder oxidation, oxygen diffusion through mastic phase, and oxygen percolation throughout the air voids structure. In this study, laboratory aging trials were conducted on mixtures prepared using component materials of several field projects throughout the USA and Canada. Laboratory aged materials were compared against field cores sampled at different ages. Results suggested that oven aging of loose mixture at 95°C is the most promising laboratory long-term aging method. Additionally, an empirical model was developed in order to account for the effect of mineral fillers on age hardening rates in asphalt mixtures. Kinetics modeling was used to predict field aging levels throughout pavement thickness and to determine the required laboratory aging duration to match field aging. Kinetics model outputs are calibrated using measured data from the field to account for the effects of oxygen diffusion and percolation. Finally, the calibrated model was validated using independent set of field sections. This work is expected to provide basis for improved asphalt mixture and pavement design procedures in order to save taxpayers' money.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4485390','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4485390"><span>Country, Sex, and Parent Occupational Status: Moderators of the Continuity of Aggression from Childhood to Adulthood</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Kokko, Katja; Simonton, Sharon; Dubow, Eric; Lansford, Jennifer E.; Olson, Sheryl L.; Huesmann, L. Rowell; Boxer, Paul; Pulkkinen, Lea; Bates, John E.; Dodge, Kenneth A.; Pettit, Gregory S.</p> <p>2015-01-01</p> <p>Using data from two American and one Finnish long-term longitudinal studies, we examined continuity of general aggression from age 8 to physical aggression in early adulthood (age 21–30) and whether continuity of aggression differed by country, sex, and parent occupational status. In all samples, childhood aggression was assessed via peer nominations and early adulthood aggression via self-reports. Multi-group structural equation models revealed significant continuity in aggression in the American samples but not in the Finnish sample. These relations did not differ by sex but did differ by parent occupational status: whereas there was no significant continuity among American children from professional family-of-origin backgrounds, there was significant continuity among American children from non-professional backgrounds. PMID:24990543</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018E%26PSL.481..372C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018E%26PSL.481..372C"><span>Old formation ages of igneous clasts on the L chondrite parent body reflect an early generation of planetesimals or chondrule formation</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Crowther, Sarah A.; Filtness, Michal J.; Jones, Rhian H.; Gilmour, Jamie D.</p> <p>2018-01-01</p> <p>The Barwell meteorite contains large, abundant clasts that are igneous in nature. We report iodine-xenon ages of five clasts and one sample of host chondrite material. The fragment of host chondrite material yielded the oldest age determined: 4567.8 ± 1.2 Ma. Two clasts produced old, well defined ages of 4564.96 ± 0.33 Ma and 4565.60 ± 0.33 Ma. These, and a third clast having a less precise old age of 4566.0 ± 3.2 Ma, are interpreted as recording the timing of crystallisation of the samples. They were incorporated into the Barwell parent body before it underwent thermal metamorphism, but the I-Xe ages survived secondary processing on the parent body and were not reset by metamorphism, metasomatism or shock. Two further clasts record younger ages of 4560.96 ± 0.45 Ma and 4554.22 ± 0.38 Ma. These samples contain a high abundance of albitic mesostasis, and the most likely explanation of the ages is that they record the timing of metasomatism on the parent body. We also analysed four host chondrite samples that do not give I-Xe ages: in these samples, the system appears to have been disturbed by shock. It has been suggested previously that the igneous clasts are derived from an early generation of partially melted asteroids. We do not have direct evidence that the clasts we examined were necessarily derived from a partially differentiated body, only that they were derived from cooling of a silicate melt; the clasts could thus be the products of any one of several proposed models for chondrule formation. Our results indicate that processes akin to chondrule formation, in that they involve rapid cooling of a silicate melt, were ongoing at the same time as CAI formation, lending support to the suggestion that Al-Mg chondrule ages indicate either heterogeneous distribution of 26Al or resetting of the Al-Mg system after chondrule formation.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19928042','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19928042"><span>Two means of sampling sexual minority women: how different are the samples of women?</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Boehmer, Ulrike; Clark, Melissa; Timm, Alison; Ozonoff, Al</p> <p>2008-01-01</p> <p>We compared 2 sampling approaches of sexual minority women in 1 limited geographic area to better understand the implications of these 2 sampling approaches. Sexual minority women identified through the Census did not differ on average age or the prevalence of raising children from those sampled using nonrandomized methods. Women in the convenience sample were better educated and lived in smaller households. Modeling the likelihood of disability in this population resulted in contradictory parameter estimates by sampling approach. The degree of variation observed both between sampling approaches and between different parameters suggests that the total population of sexual minority women is still unmeasured. Thoroughly constructed convenience samples will continue to be a useful sampling strategy to further research on this population.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21711129','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21711129"><span>Confirmation of the three-factor model of problematic internet use on off-line adolescent and adult samples.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Koronczai, Beatrix; Urbán, Róbert; Kökönyei, Gyöngyi; Paksi, Borbála; Papp, Krisztina; Kun, Bernadette; Arnold, Petra; Kállai, János; Demetrovics, Zsolt</p> <p>2011-11-01</p> <p>As the Internet became widely used, problems associated with its excessive use became increasingly apparent. Although for the assessment of these problems several models and related questionnaires have been elaborated, there has been little effort made to confirm them. The aim of the present study was to test the three-factor model of the previously created Problematic Internet Use Questionnaire (PIUQ) by data collection methods formerly not applied (off-line group and face-to-face settings), on the one hand, and by testing on different age groups (adolescent and adult representative samples), on the other hand. Data were collected from 438 high-school students (44.5 percent boys; mean age: 16.0 years; standard deviation=0.7 years) and also from 963 adults (49.9 percent males; mean age: 33.6 years; standard deviation=11.8 years). We applied confirmatory factor analysis to confirm the measurement model of problematic Internet use. The results of the analyses carried out inevitably support the original three-factor model over the possible one-factor solution. Using latent profile analysis, we identified 11 percent of adults and 18 percent of adolescent users characterized by problematic use. Based on exploratory factor analysis, we also suggest a short form of the PIUQ consisting of nine items. Both the original 18-item version of PIUQ and its short 9-item form have satisfactory reliability and validity characteristics, and thus, they are suitable for the assessment of problematic Internet use in future studies.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28057473','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28057473"><span>Analysis of longitudinal diffusion-weighted images in healthy and pathological aging: An ADNI study.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kruggel, Frithjof; Masaki, Fumitaro; Solodkin, Ana</p> <p>2017-02-15</p> <p>The widely used framework of voxel-based morphometry for analyzing neuroimages is extended here to model longitudinal imaging data by exchanging the linear model with a linear mixed-effects model. The new approach is employed for analyzing a large longitudinal sample of 756 diffusion-weighted images acquired in 177 subjects of the Alzheimer's Disease Neuroimaging initiative (ADNI). While sample- and group-level results from both approaches are equivalent, the mixed-effect model yields information at the single subject level. Interestingly, the neurobiological relevance of the relevant parameter at the individual level describes specific differences associated with aging. In addition, our approach highlights white matter areas that reliably discriminate between patients with Alzheimer's disease and healthy controls with a predictive power of 0.99 and include the hippocampal alveus, the para-hippocampal white matter, the white matter of the posterior cingulate, and optic tracts. In this context, notably the classifier includes a sub-population of patients with minimal cognitive impairment into the pathological domain. Our classifier offers promising features for an accessible biomarker that predicts the risk of conversion to Alzheimer's disease. Data used in preparation of this article were obtained from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database (adni.loni.usc.edu). As such, the investigators within the ADNI contributed to the design and implementation of ADNI and/or provided data but did not participate in analysis or writing of this report. A complete listing of ADNI investigators can be found at: http://adni.loni.usc.edu/wp-content/uploads/how to apply/ADNI Acknowledgement List.pdf. Significance statement This study assesses neuro-degenerative processes in the brain's white matter as revealed by diffusion-weighted imaging, in order to discriminate healthy from pathological aging in a large sample of elderly subjects. The analysis of time-series examinations in a linear mixed effects model allowed the discrimination of population-based aging processes from individual determinants. We demonstrate that a simple classifier based on white matter imaging data is able to predict the conversion to Alzheimer's disease with a high predictive power. Copyright © 2017 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28587592','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28587592"><span>Bayesian hierarchical piecewise regression models: a tool to detect trajectory divergence between groups in long-term observational studies.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Buscot, Marie-Jeanne; Wotherspoon, Simon S; Magnussen, Costan G; Juonala, Markus; Sabin, Matthew A; Burgner, David P; Lehtimäki, Terho; Viikari, Jorma S A; Hutri-Kähönen, Nina; Raitakari, Olli T; Thomson, Russell J</p> <p>2017-06-06</p> <p>Bayesian hierarchical piecewise regression (BHPR) modeling has not been previously formulated to detect and characterise the mechanism of trajectory divergence between groups of participants that have longitudinal responses with distinct developmental phases. These models are useful when participants in a prospective cohort study are grouped according to a distal dichotomous health outcome. Indeed, a refined understanding of how deleterious risk factor profiles develop across the life-course may help inform early-life interventions. Previous techniques to determine between-group differences in risk factors at each age may result in biased estimate of the age at divergence. We demonstrate the use of Bayesian hierarchical piecewise regression (BHPR) to generate a point estimate and credible interval for the age at which trajectories diverge between groups for continuous outcome measures that exhibit non-linear within-person response profiles over time. We illustrate our approach by modeling the divergence in childhood-to-adulthood body mass index (BMI) trajectories between two groups of adults with/without type 2 diabetes mellitus (T2DM) in the Cardiovascular Risk in Young Finns Study (YFS). Using the proposed BHPR approach, we estimated the BMI profiles of participants with T2DM diverged from healthy participants at age 16 years for males (95% credible interval (CI):13.5-18 years) and 21 years for females (95% CI: 19.5-23 years). These data suggest that a critical window for weight management intervention in preventing T2DM might exist before the age when BMI growth rate is naturally expected to decrease. Simulation showed that when using pairwise comparison of least-square means from categorical mixed models, smaller sample sizes tended to conclude a later age of divergence. In contrast, the point estimate of the divergence time is not biased by sample size when using the proposed BHPR method. BHPR is a powerful analytic tool to model long-term non-linear longitudinal outcomes, enabling the identification of the age at which risk factor trajectories diverge between groups of participants. The method is suitable for the analysis of unbalanced longitudinal data, with only a limited number of repeated measures per participants and where the time-related outcome is typically marked by transitional changes or by distinct phases of change over time.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27544616','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27544616"><span>Characterization of mechanical properties of lamellar structure of the aortic wall: Effect of aging.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Taghizadeh, Hadi; Tafazzoli-Shadpour, Mohammad</p> <p>2017-01-01</p> <p>Arterial wall tissues are sensitive to their mechanical surroundings and remodel their structure and mechanical properties when subjected to mechanical stimuli such as increased arterial pressure. Such remodeling is evident in hypertension and aging. Aging is characterized by stiffening of the artery wall which is assigned to disturbed elastin function and increased collagen content. To better understand and provide new insight on microstructural changes induced by aging, the lamellar model of the aortic media was utilized to characterize and compare wall structure and mechanical behavior of the young and old human thoracic aortic samples. Such model regards arterial media as two sets of alternating concentric layers, namely sheets of elastin and interlamellar layers. Histological and biaxial tests were performed and microstructural features and stress-strain curves of media were evaluated in young and old age groups. Then using optimization algorithms and hyperelastic constitutive equations the stress-strain curves of layers were evaluated for both age groups. Results indicated slight elevation in the volume fraction of interlamellar layer among old subjects most probably due to age related collagen deposition. Aging indicated substantial stiffening of interlamellar layers accompanied by noticeable softening of elastic lamellae. The general significant stiffening of old samples were attributed to both increase of volume fraction of interlamellar layers and earlier recruitment of collagen fibers during load bearing due to functional loss of elastin within wall lamellae. Mechanical characterization of lamellar structure of wall media is beneficial in study of arterial remodeling in response to alternated mechanical environment in aging and clinical conditions through coupling of wall microstructure and mechanical behavior. Copyright © 2016 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016E%26PSL.451..149S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016E%26PSL.451..149S"><span>Lunar basalt chronology, mantle differentiation and implications for determining the age of the Moon</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Snape, Joshua F.; Nemchin, Alexander A.; Bellucci, Jeremy J.; Whitehouse, Martin J.; Tartèse, Romain; Barnes, Jessica J.; Anand, Mahesh; Crawford, Ian A.; Joy, Katherine H.</p> <p>2016-10-01</p> <p>Despite more than 40 years of studying Apollo samples, the age and early evolution of the Moon remain contentious. Following the formation of the Moon in the aftermath of a giant impact, the resulting Lunar Magma Ocean (LMO) is predicted to have generated major geochemically distinct silicate reservoirs, including the sources of lunar basalts. Samples of these basalts, therefore, provide a unique opportunity to characterize these reservoirs. However, the precise timing and extent of geochemical fractionation is poorly constrained, not least due to the difficulty in determining accurate ages and initial Pb isotopic compositions of lunar basalts. Application of an in situ ion microprobe approach to Pb isotope analysis has allowed us to obtain precise crystallization ages from six lunar basalts, typically with an uncertainty of about ± 10 Ma, as well as constrain their initial Pb-isotopic compositions. This has enabled construction of a two-stage model for the Pb-isotopic evolution of lunar silicate reservoirs, which necessitates the prolonged existence of high-μ reservoirs in order to explain the very radiogenic compositions of the samples. Further, once firm constraints on U and Pb partitioning behaviour are established, this model has the potential to help distinguish between conflicting estimates for the age of the Moon. Nonetheless, we are able to constrain the timing of a lunar mantle reservoir differentiation event at 4376 ± 18 Ma, which is consistent with that derived from the Sm-Nd and Lu-Hf isotopic systems, and is interpreted as an average estimate of the time at which the high-μ urKREEP reservoir was established and the Ferroan Anorthosite (FAN) suite was formed.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5366256','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5366256"><span>Victimization, Suicidal Ideation, and Alcohol Use From Age 13 to 15 Years: Support for the Self-Medication Model</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Marschall-Lévesque, Shawn; Castellanos-Ryan, Natalie; Parent, Sophie; Renaud, Johanne; Vitaro, Frank; Boivin, Michel; Tremblay, Richard E.; Séguin, Jean R.</p> <p>2017-01-01</p> <p>Purpose Recent years have seen increased coverage of adolescent victimization and suicide. Both adolescent peer victimization and substance use have been associated with suicidal ideation, with evidence suggesting that all three factors are interrelated. There are at least four models which can explain the associations between these factors (i.e., self-medication, secondary mental disorder, bidirectional, and common factor). However, none of them is being empirically supported as the dominant model because few longitudinal studies have explored the association between these factors. Methods The present study compared longitudinal paths of all four models simultaneously using a cross-lagged model. This was done using self-reported measures of peer victimization, suicidal ideation, and alcohol use at age 13, 14, and 15 years in a longitudinal sample of 238 adolescents. Results All three variables were moderately stable across time. Significant cross-lagged associations were found, showing that frequent peer victimization at age 13 years was associated with higher odds of having suicidal ideation at age 14 years (odds ratio, 1.82; p < .05). In turn, presence of suicidal ideation at age 14 years was significantly associated with higher alcohol use frequency at age 15 years (β = .13; p < .05). Conclusions Results support previous literature suggesting that peer victimization predates alcohol use and extends it by showing clear directionality between suicidal ideation and alcohol use over 1 year, supporting the self-medication model. Clarifying the empirical basis of these underlying models could allow for earlier prevention strategies, by targeting the risk factor that appears the earliest in the model. PMID:27914973</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li class="active"><span>22</span></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_22 --> <div id="page_23" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li class="active"><span>23</span></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="441"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24559006','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24559006"><span>[Anthropometric model for the prediction of appendicular skeletal muscle mass in Chilean older adults].</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lera, Lydia; Albala, Cecilia; Ángel, Bárbara; Sánchez, Hugo; Picrin, Yaisy; Hormazabal, María José; Quiero, Andrea</p> <p>2014-03-01</p> <p>To develop a predictive model of appendicular skeletal muscle mass (ASM) based on anthropometric measurements in elderly from Santiago, Chile. 616 community dwelling, non-disabled subjects ≥ 60 years (mean 69.9 ± 5.2 years) living in Santiago, 64.6% female, participating in ALEXANDROS study. Anthropometric measurements, handgrip strength, mobility tests and DEXA were performed. Step by step linear regression models were used to associate ASM from DEXA with anthropometric variables, age and sex. The sample was divided at random into two to obtain prediction equations for both subsamples, which were mutually validated by double cross-validation. The high correlation between the values of observed and predicted MMAE in both sub-samples and the low degree of shrinkage allowed developing the final prediction equation with the total sample. The cross-validity coefficient between prediction models from the subsamples (0.941 and 0.9409) and the shrinkage (0.004 and 0.006) were similar in both equations. The final prediction model obtained from the total sample was: ASM (kg) = 0.107(weight in kg) + 0.251( knee height in cm) + 0.197 (Calf Circumference in cm) +0.047 (dynamometry in kg) - 0.034 (Hip Circumference in cm) + 3.417 (Man) - 0.020 (age years) - 7.646 (R2 = 0.89). The mean ASM obtained by the prediction equation and the DEXA measurement were similar (16.8 ± 4.0 vs 16.9 ± 3.7) and highly concordant according Bland and Altman (95% CI: -2.6 -2.7) and Lin (concordance correlation coefficient = 0.94) methods. We obtained a low cost anthropometric equation to determine the appendicular skeletal muscle mass useful for the screening of sarcopenia in older adults. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26423363','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26423363"><span>From perceived autonomy support to intentional behaviour: Testing an integrated model in three healthy-eating behaviours.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Girelli, Laura; Hagger, Martin; Mallia, Luca; Lucidi, Fabio</p> <p>2016-01-01</p> <p>A motivational model integrating self-determination theory, the theory of planned behaviour, and the health action process approach was tested in three samples in three behavioural contexts: fruit and vegetable, breakfast, and snack consumption. Perceived support for autonomous (self-determined) forms of motivation from parents and autonomous motivation from self-determination theory were hypothesised to predict intention and behaviour indirectly via the mediation of attitude and perceived behavioural control from the theory of planned behaviour. It was also expected that planning strategies would mediate the effect of intention on behaviour. Relations in the proposed models were expected to be similar across the behaviours. A two-wave prospective design was adopted. Three samples of high-school students (total N = 1041; 59.60% female; M age = 17.13 years ± 1.57) completed measures of perceived autonomy support, autonomous motivation, theory of planned behaviour constructs, planning strategies and behaviour for each of the three behavioural contexts. Three months later, 816 participants (62,24% female; M age: 17.13 years, SD = 1.58) of the initial sample self-reported their behaviour referred to the previous three months. Structural equation models provided support for the key hypothesised effects of the proposed model for the three health-related behaviours. Two direct effects were significantly different across the three behaviours: the effect of perceived autonomy support on perceived behavioural control and the effect of attitude on intention. In addition, planning strategies mediated the effect of intention on behaviour in fruit and vegetable sample only. Findings extend knowledge of the processes by which psychological antecedents from the theories affect energy-balance related behaviours. Copyright © 2015 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4591021','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4591021"><span>The Model Human Processor and the Older Adult: Parameter Estimation and Validation Within a Mobile Phone Task</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Jastrzembski, Tiffany S.; Charness, Neil</p> <p>2009-01-01</p> <p>The authors estimate weighted mean values for nine information processing parameters for older adults using the Card, Moran, and Newell (1983) Model Human Processor model. The authors validate a subset of these parameters by modeling two mobile phone tasks using two different phones and comparing model predictions to a sample of younger (N = 20; Mage = 20) and older (N = 20; Mage = 69) adults. Older adult models fit keystroke-level performance at the aggregate grain of analysis extremely well (R = 0.99) and produced equivalent fits to previously validated younger adult models. Critical path analyses highlighted points of poor design as a function of cognitive workload, hardware/software design, and user characteristics. The findings demonstrate that estimated older adult information processing parameters are valid for modeling purposes, can help designers understand age-related performance using existing interfaces, and may support the development of age-sensitive technologies. PMID:18194048</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21550588','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21550588"><span>Third molar development: measurements versus scores as age predictor.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Thevissen, P W; Fieuws, S; Willems, G</p> <p>2011-10-01</p> <p>Human third molar development is widely used to predict chronological age of sub adult individuals with unknown or doubted age. For these predictions, classically, the radiologically observed third molar growth and maturation is registered using a staging and related scoring technique. Measures of lengths and widths of the developing wisdom tooth and its adjacent second molar can be considered as an alternative registration. The aim of this study was to verify relations between mandibular third molar developmental stages or measurements of mandibular second molar and third molars and age. Age related performance of stages and measurements were compared to assess if measurements added information to age predictions from third molar formation stage. The sample was 340 orthopantomograms (170 females, 170 males) of individuals homogenously distributed in age between 7 and 24 years. Mandibular lower right, third and second molars, were staged following Gleiser and Hunt, length and width measurements were registered, and various ratios of these measurements were calculated. Univariable regression models with age as response and third molar stage, measurements and ratios of second and third molars as predictors, were considered. Multivariable regression models assessed if measurements or ratios added information to age prediction from third molar stage. Coefficients of determination (R(2)) and root mean squared errors (RMSE) obtained from all regression models were compared. The univariable regression model using stages as predictor yielded most accurate age predictions (males: R(2) 0.85, RMSE between 0.85 and 1.22 year; females: R(2) 0.77, RMSE between 1.19 and 2.11 year) compared to all models including measurements and ratios. The multivariable regression models indicated that measurements and ratios added no clinical relevant information to the age prediction from third molar stage. Ratios and measurements of second and third molars are less accurate age predictors than stages of developing third molars. Copyright © 2011 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25389038','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25389038"><span>Ink dating using thermal desorption and gas chromatography/mass spectrometry: comparison of results obtained in two laboratories.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Koenig, Agnès; Bügler, Jürgen; Kirsch, Dieter; Köhler, Fritz; Weyermann, Céline</p> <p>2015-01-01</p> <p>An ink dating method based on solvent analysis was recently developed using thermal desorption followed by gas chromatography/mass spectrometry (GC/MS) and is currently implemented in several forensic laboratories. The main aims of this work were to implement this method in a new laboratory to evaluate whether results were comparable at three levels: (i) validation criteria, (ii) aging curves, and (iii) results interpretation. While the results were indeed comparable in terms of validation, the method proved to be very sensitive to maintenances. Moreover, the aging curves were influenced by ink composition, as well as storage conditions (particularly when the samples were not stored in "normal" room conditions). Finally, as current interpretation models showed limitations, an alternative model based on slope calculation was proposed. However, in the future, a probabilistic approach may represent a better solution to deal with ink sample inhomogeneity. © 2014 American Academy of Forensic Science.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017ApJ...837...36L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017ApJ...837...36L"><span>Energetics and Birth Rates of Supernova Remnants in the Large Magellanic Cloud</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Leahy, D. A.</p> <p>2017-03-01</p> <p>Published X-ray emission properties for a sample of 50 supernova remnants (SNRs) in the Large Magellanic Cloud (LMC) are used as input for SNR evolution modeling calculations. The forward shock emission is modeled to obtain the initial explosion energy, age, and circumstellar medium density for each SNR in the sample. The resulting age distribution yields a SNR birthrate of 1/(500 yr) for the LMC. The explosion energy distribution is well fit by a log-normal distribution, with a most-probable explosion energy of 0.5× {10}51 erg, with a 1σ dispersion by a factor of 3 in energy. The circumstellar medium density distribution is broader than the explosion energy distribution, with a most-probable density of ˜0.1 cm-3. The shape of the density distribution can be fit with a log-normal distribution, with incompleteness at high density caused by the shorter evolution times of SNRs.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28277943','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28277943"><span>Microaggressions and marijuana use among college students.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Pro, George; Sahker, Ethan; Marzell, Miesha</p> <p>2017-03-09</p> <p>This study examines the association between exposure to microaggressions and marijuana use, using original survey data from a sample of racial/ethnic minority college students (n = 332) from a large Division I university in the United States. Nearly all of our sample (96%) reported at least one experience with microaggressions in the past 6 months, while 33% reported using marijuana regularly. We modeled regular use of marijuana using multiple logistic regression, with consideration of sex, age, race/ethnicity, and microaggression scale scores as covariates. Age, sex, the microinvalidations subscale score, and the full microaggression scale score were significantly associated with marijuana use in our full models (p < .01; p = .01; p = .02; p = .03, respectively). With each additional experience of microaggression, the odds of regular marijuana use increase. Academic communities may consider the primary prevention of discriminatory behavior when addressing student substance use.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28702771','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28702771"><span>Evidence for the Trait-Impulsivity Etiological Model in a Clinical Sample: Bifactor Structure and Its Relation to Impairment and Environmental Risk.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Rodenacker, Klaas; Hautmann, Christopher; Görtz-Dorten, Anja; Döpfner, Manfred</p> <p>2018-05-01</p> <p>The trait-impulsivity etiological model assumes that a general factor (trait-impulsivity) underlies attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), and other externalizing disorders. We investigated the plausibility of this assumption by testing the factor structure of ADHD and ODD in a bifactor framework for a clinical sample of 1420 children between 6 and 18 years of age (M = 9.99, SD = 3.34; 85% male). Further, the trait-impulsivity etiological model assumes that ODD emerges only if environmental risk factors are present. Our results support the validity of the trait-impulsivity etiological model, as they confirm that ADHD and ODD share a strong general factor of disruptive behavior (DB) in this clinical sample. Furthermore, unlike the subdimensions of ADHD, we found that the specific ODD factor explained as much true score variance as the general DB factor. This suggests that a common scale of ADHD and ODD may prove to be as important as a separate ODD subscale to assess externalizing problems in school-age children. However, all other subscales of ADHD may not explain sufficient true score variance once the impact of the general DB factor has been taken into consideration. In accordance with the trait-impulsivity model, we also showed that all factors, but predominantly the general factor and specific inattention factor, predicted parent-rated impairment, and that predominantly ODD and impulsivity are predicted by environmental risk factors.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3805285','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3805285"><span>Are “Anti-Aging Medicine” and “Successful Aging” Two Sides of the Same Coin? Views of Anti-Aging Practitioners</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2013-01-01</p> <p>Objectives. This article analyzes data from interviews with anti-aging practitioners to evaluate how their descriptions of the work they do, their definitions of aging, and their goals for their patients intersect with gerontological views of “successful aging.” Method. Semistructured interviews were conducted with a sample of 31 anti-aging practitioners drawn from the directory of the American Academy for Anti-Aging Medicine. Results. Qualitative analysis of the transcripts demonstrate that practitioners’ descriptions of their goals, intentionally or unintentionally, mimic the dominant models of “successful aging.” These include lowered risk of disease and disability, maintenance of high levels of mental and physical function, and continuing social engagement. Yet, the means and modes of achieving these goals differ markedly between the two groups, as do the messages that each group puts forth in defending their positions. Discussion. Anti-aging practitioners’ adoption of the rhetoric of successful aging reflects the success of successful aging models in shaping popular conceptions of what aging is and an ethos of management and control over the aging process. The overlap between anti-aging and successful aging rhetoric also highlights some of the most problematic social, cultural, and economic consequences of efforts made to reconceptualize old age. PMID:24022620</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=cognition+AND+memory&pg=2&id=EJ999680','ERIC'); return false;" href="https://eric.ed.gov/?q=cognition+AND+memory&pg=2&id=EJ999680"><span>Gender Differences in Cognition among Older Adults in China</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Lei, Xiaoyan; Hu, Yuqing; McArdle, John J.; Smith, James P.; Zhao, Yaohui</p> <p>2012-01-01</p> <p>In this paper, we model gender differences in cognitive ability in China using a new sample of middle-aged and older Chinese respondents. Modeled after the American Health and Retirement Study (HRS), the CHARLS Pilot survey respondents are 45 years and older in two quite distinct provinces--Zhejiang, a high-growth industrialized province on the…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=age+AND+early+AND+primary&pg=7&id=EJ887180','ERIC'); return false;" href="https://eric.ed.gov/?q=age+AND+early+AND+primary&pg=7&id=EJ887180"><span>Perceived Stress and Wellness in Early Adolescents Using the Neuman Systems Model</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Yarcheski, Thomas J.; Mahon, Noreen E.; Yarcheski, Adela; Hanks, Michele M.</p> <p>2010-01-01</p> <p>The purpose of this study was to examine the relationship between perceived stress and wellness in early adolescents and to test primary appraisal as a mediator of this relationship using the Neuman Systems Model as the primary framework. The sample consisted of 144 adolescents, ages 12-14, who responded to instruments measuring perceived stress,…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ1109436.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ1109436.pdf"><span>Prediction of Emotional Understanding and Emotion Regulation Skills of 4-5 Age Group Children with Parent-Child Relations</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Dereli, Esra</p> <p>2016-01-01</p> <p>The objective of the present study is to examine whether personal attributes, family characteristics of the child and parent-child relations predict children's emotional understanding and emotion regulation skills. The study was conducted with relational screening model, one of the screening models. Study sample included 423 children between the…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ805086.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ805086.pdf"><span>Modeling the Effects of Early Childhood Intervention Variables on Parent and Family Well-Being</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Dunst, Carl J.; Hamby, Deborah W.; Brookfield, Jeffri</p> <p>2007-01-01</p> <p>Structural equation modeling was used to evaluate the effects of family, child, and both early childhood intervention process and structural variables on parent and family well-being in a sample of 250 parents involved in birth to age three early childhood intervention programs. Family SES and income had direct positive effects, family-centered…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=Optimism&pg=5&id=EJ1073154','ERIC'); return false;" href="https://eric.ed.gov/?q=Optimism&pg=5&id=EJ1073154"><span>Career Goals in Young Adults: Personal Resources, Goal Appraisals, Attitudes, and Goal Management Strategies</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Haratsis, Jessica M.; Hood, Michelle; Creed, Peter A.</p> <p>2015-01-01</p> <p>We tested a model based on the dual-process framework that assessed the relationships among personal resources, career goal appraisals, career attitudes, and career goal management, which have not been previously assessed together. The model (tested on a sample of 486 young adults: 74% female, M[subscript]age = 22 years) proposed that personal…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2920151','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2920151"><span>Mediation and moderation: Testing relationships between symptom status, functional health, and quality of life in HIV patients</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Ryu, Ehri; West, Stephen G.; Sousa, Karen H.</p> <p>2010-01-01</p> <p>We extended Wilson and Cleary's (1995) health-related quality of life model to examine the relationships among symptoms status (Symptoms), functional health (Disability), and quality of life (QOL). Using a community sample (N = 956) of male HIV positive patients, we tested a mediation model in which the relationship between Symptoms and QOL is partially mediated by Disability. Common and unique ideas from three approaches to examining moderation of effects in mediational models (Edwards & Lambert, 2007; Preacher, Rucker, & Hayes, 2007; MacKinnon, 2008) were used to test whether (a) the direct relationship of Symptoms to QOL and (b) the relationship of Disability to QOL are moderated by age. In the mediation model, both the direct and the indirect (mediated) effects were significant. The direct relationship of Symptoms to QOL was significantly moderated by age, but the relationship of Disability to QOL was not. High Symptoms were associated with lower QOL at all ages, but that this relationship became stronger at older ages. We compare the three approaches and consider their advantages over traditional approaches to combining mediation and moderation. PMID:20706561</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27049449','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27049449"><span>Evolving Spiking Neural Networks for Recognition of Aged Voices.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Silva, Marco; Vellasco, Marley M B R; Cataldo, Edson</p> <p>2017-01-01</p> <p>The aging of the voice, known as presbyphonia, is a natural process that can cause great change in vocal quality of the individual. This is a relevant problem to those people who use their voices professionally, and its early identification can help determine a suitable treatment to avoid its progress or even to eliminate the problem. This work focuses on the development of a new model for the identification of aging voices (independently of their chronological age), using as input attributes parameters extracted from the voice and glottal signals. The proposed model, named Quantum binary-real evolving Spiking Neural Network (QbrSNN), is based on spiking neural networks (SNNs), with an unsupervised training algorithm, and a Quantum-Inspired Evolutionary Algorithm that automatically determines the most relevant attributes and the optimal parameters that configure the SNN. The QbrSNN model was evaluated in a database composed of 120 records, containing samples from three groups of speakers. The results obtained indicate that the proposed model provides better accuracy than other approaches, with fewer input attributes. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2745992','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2745992"><span>Reciprocal Associations between Boys’ Externalizing Problems and Mothers’ Depressive Symptoms</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Shaw, Daniel S.; Moilanen, Kristin L.</p> <p>2009-01-01</p> <p>Although much has been written about the utility of applying transactional models to the study of parenting practices, relatively few researchers have used such an approach to examine how children influence maternal wellbeing throughout their development. Using a sample of males from predominantly low-income families, the current study explored reciprocal relations between boys’ overt disruptive behavior (boys’ ages 5 to 10 years) and maternal depressive symptoms. We then examined this model with youth-reported antisocial behaviors (ASB) and maternal depressive symptoms when the boys were older, ages 10 to 15. In middle childhood, evidence was found for both maternal and child effects from boys’ ages 5 to 6 using both maternal and alternative caregiver report of child aggressive behavior. In the early adolescence model, consistent maternal effects were found, and child effects were evident during the transition to adolescence (boys’ ages 11 to 12). The findings are discussed in reference to reciprocal models of child development and prevention efforts to reduce both maternal depression and the prevalence of child antisocial behavior. PMID:18288602</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=depression+AND+statistic&pg=2&id=EJ1019350','ERIC'); return false;" href="https://eric.ed.gov/?q=depression+AND+statistic&pg=2&id=EJ1019350"><span>Symptoms of Depression Depend on Rigid Parenting Attitudes, Gender, and Race in an At-Risk Sample of Early Adolescents</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Weed, Keri; Morales, Dawn A.; Harjes, Rachel</p> <p>2013-01-01</p> <p>Trajectories of depressive symptoms were compared between European American and African American boys and girls from ages 8 to 14 in a longitudinal sample of 130 children born to adolescent mothers. Mixed-effects regression modeling was used to analyze individual and group differences in level of depressive symptoms and their changes over time.…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=positive+AND+negative+AND+affect&id=EJ934380','ERIC'); return false;" href="https://eric.ed.gov/?q=positive+AND+negative+AND+affect&id=EJ934380"><span>A Psychometric Analysis of the Positive and Negative Affect Schedule for Children-Parent Version in a School Sample</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Ebesutani, Chad; Okamura, Kelsie; Higa-McMillan, Charmaine; Chorpita, Bruce F.</p> <p>2011-01-01</p> <p>The current study was the 1st to examine the psychometric properties of the Positive and Negative Affect Schedule for Children-Parent Version (PANAS-C-P) using a large school-based sample of children and adolescents ages 8 to 18 (N = 606). Confirmatory factor analysis supported a 2-factor (correlated) model of positive affect (PA) and negative…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AGUFM.C21E1159T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AGUFM.C21E1159T"><span>The Holocene Minimum of the West Antarctic Ice Sheet: Radiocarbon Model Ages for Subglacial Sediments</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Tulaczyk, S. M.; Stansell, N.; Scherer, R. P.; Powell, R. D.</p> <p>2017-12-01</p> <p>It is commonly assumed that the West Antarctic Ice Sheet (WAIS) is at the present time as small as it has been since at least the last interglacial period about 125,000 years ago. Yet, our recent analyses of subglacial sediments recovered from beneath the ice sheet indicate regionally widespread presence of radiocarbon. This unstable isotope with half life of 5,730 years should decay to nil if the analyzed subglacial sediment samples have been isolated beneath the ice sheet from the atmosphere and the ocean for 125,000 years (over 20 half lives). However, the apparent radiocarbon ages for these samples are in the range of about 20,000-30,000 years BP, based on radiocarbon Fraction Modern (FM) of a few to several percent. The apparent sediment ages cannot be taken at face value because: (1) they overlap with the Last Glacial Maximum (LGM) when WAIS is known to have extended over 1,000 km past the sediment sampling locations, and (2) Antarctic glacigenic sediments commonly contain significant admixture of old, radiocarbon-dead organic matter. The latter biases apparent radiocarbon ages because it violates the assumption that the initial radiocarbon fraction in a sample was equal to FM. To mitigate the problem with apparent ages, we assume that initial radiocarbon fraction in subglacial sediments was equal to that determined by us independently in J-9 sediments from beneath the Ross Ice Shelf (RIS) and calculate radiocarbon 'model ages' between 1,000 and 6,000 years BP. This period of time overlaps with a regional climatic optimum and with late phases of post-LGM glacioisostatic adjustment in the region (e.g., Kingslake et al., this session). We propose that the grounding line of WAIS, at least on the RIS side, retreated in mid/late Holocene more than 300 km beyond its current position and then re-advanced to reach its modern geometry. This implies that the main body of WAIS was significantly smaller than today in mid/late Holocene and that the ice sheet is capable of large fluctuations on timescales much shorter than previously expected.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li class="active"><span>23</span></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_23 --> <div id="page_24" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li class="active"><span>24</span></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="461"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015Litho.238...37M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015Litho.238...37M"><span>Argon behaviour in an inverted Barrovian sequence, Sikkim Himalaya: The consequences of temperature and timescale on 40Ar/39Ar mica geochronology</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Mottram, Catherine M.; Warren, Clare J.; Halton, Alison M.; Kelley, Simon P.; Harris, Nigel B. W.</p> <p>2015-12-01</p> <p>40Ar/39Ar dating of metamorphic rocks sometimes yields complicated datasets which are difficult to interpret in terms of timescales of the metamorphic cycle. Single-grain fusion and step-heating data were obtained for rocks sampled through a major thrust-sense shear zone (the Main Central Thrust) and the associated inverted metamorphic zone in the Sikkim region of the eastern Himalaya. This transect provides a natural laboratory to explore factors influencing apparent 40Ar/39Ar ages in similar lithologies at a variety of metamorphic pressure and temperature (P-T) conditions. The 40Ar/39Ar dataset records progressively younger apparent age populations and a decrease in within-sample dispersion with increasing temperature through the sequence. The white mica populations span 2-9 Ma within each sample in the structurally lower levels (garnet grade) but only 0-3 Ma at structurally higher levels (kyanite-sillimanite grade). Mean white mica single-grain fusion population ages vary from 16.2 ± 3.9 Ma (2σ) to 13.2 ± 1.3 Ma (2σ) from lowest to highest levels. White mica step-heating data from the same samples yields plateau ages from 14.27 ± 0.13 Ma to 12.96 ± 0.05 Ma. Biotite yield older apparent age populations with mean single-grain fusion dates varying from 74.7 ± 11.8 Ma (2σ) at the lowest structural levels to 18.6 ± 4.7 Ma (2σ) at the highest structural levels; the step-heating plateaux are commonly disturbed. Temperatures > 600 °C at pressures of 0.4-0.8 GPa sustained over > 5 Ma, appear to be required for white mica and biotite ages to be consistent with diffusive, open-system cooling. At lower temperatures, and/or over shorter metamorphic timescales, more 40Ar is retained than results from simple diffusion models suggest. Diffusion modelling of Ar in white mica from the highest structural levels suggests that the high-temperature rocks cooled at a rate of 50-80 °C Ma- 1, consistent with rapid thrusting, extrusion and exhumation along the Main Central Thrust during the mid-Miocene.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5111597','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5111597"><span>Personality and Other Lifelong Influences on Older‐Age Health and Wellbeing: Preliminary Findings in Two Scottish Samples</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Brett, Caroline E.; Starr, John M.; Deary, Ian J.</p> <p>2016-01-01</p> <p>Abstract Recent observations that personality traits are related to later‐life health and wellbeing have inspired considerable interest in exploring the mechanisms involved. Other factors, such as cognitive ability and education, also show longitudinal influences on health and wellbeing, but it is not yet clear how all these early‐life factors together contribute to later‐life health and wellbeing. In this preliminary study, we assessed hypothesised relations among these variables across the life course, using structural equation modelling in a sample assessed on dependability (a personality trait related to conscientiousness) in childhood, cognitive ability and social class in childhood and older age, education, and health and subjective wellbeing in older age. Our models indicated that both health and subjective wellbeing in older age were influenced by childhood IQ and social class, via education. Some older‐age personality traits mediated the effects of early‐life variables, on subjective wellbeing in particular, but childhood dependability did not show significant associations. Our results therefore did not provide evidence that childhood dependability promotes older‐age health and wellbeing, but did highlight the importance of other early‐life factors, particularly characteristics that contribute to educational attainment. Further, personality in later life may mediate the effects of early‐life factors on health and subjective wellbeing. © 2016 The Authors. European Journal of Personality published by John Wiley & Sons Ltd on behalf of European Association of Personality Psychology PMID:27867259</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/15011422','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/15011422"><span>Marine04 Marine radiocarbon age calibration, 26 ? 0 ka BP</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Hughen, K; Baille, M; Bard, E</p> <p>2004-11-01</p> <p>New radiocarbon calibration curves, IntCal04 and Marine04, have been constructed and internationally ratified to replace the terrestrial and marine components of IntCal98. The new calibration datasets extend an additional 2000 years, from 0-26 ka cal BP (Before Present, 0 cal BP = AD 1950), and provide much higher resolution, greater precision and more detailed structure than IntCal98. For the Marine04 curve, dendrochronologically dated tree-ring samples, converted with a box-diffusion model to marine mixed-layer ages, cover the period from 0-10.5 ka cal BP. Beyond 10.5 ka cal BP, high-resolution marine data become available from foraminifera in varved sediments and U/Th-dated corals.more » The marine records are corrected with site-specific {sup 14}C reservoir age information to provide a single global marine mixed-layer calibration from 10.5-26.0 ka cal BP. A substantial enhancement relative to IntCal98 is the introduction of a random walk model, which takes into account the uncertainty in both the calendar age and the radiocarbon age to calculate the underlying calibration curve. The marine datasets and calibration curve for marine samples from the surface mixed layer (Marine04) are discussed here. The tree-ring datasets, sources of uncertainty, and regional offsets are presented in detail in a companion paper by Reimer et al.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22697177','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22697177"><span>Individual differences and predictors of forgetting in old age: the role of processing speed and working memory.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Zimprich, Daniel; Kurtz, Tanja</p> <p>2013-01-01</p> <p>The goal of the present study was to examine whether individual differences in basic cognitive abilities, processing speed, and working memory, are reliable predictors of individual differences in forgetting rates in old age. The sample for the present study comprised 364 participants aged between 65 and 80 years from the Zurich Longitudinal Study on Cognitive Aging. The impact of basic cognitive abilities on forgetting was analyzed by modeling working memory and processing speed as predictors of the amount of forgetting of 27 words, which had been learned across five trials. Forgetting was measured over a 30-minute interval by using parceling and a latent change model, in which the latent difference between recall performance after five learning trials and a delayed recall was modeled. Results implied reliable individual differences in forgetting. These individual differences in forgetting were strongly related to processing speed and working memory. Moreover, an age-related effect, which was significantly stronger for forgetting than for learning, emerged even after controlling effects of processing speed and working memory.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70029710','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70029710"><span>Evidence for terrigenic SF6 in groundwater from basaltic aquifers, Jeju Island, Korea: Implications for groundwater dating</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Koh, Dong-Chan; Plummer, Niel; Busenberg, Eurybiades; Kim, Yongje</p> <p>2007-01-01</p> <p>Measurements of the concentrations of dichlorodifluoromethane (CFC-12), tritium (3H), and sulfur hexafluoride (SF6) in groundwater from basaltic aquifers in Jeju Island, Korea, demonstrate a terrigenic source of SF6. Using a lumped-parameter dispersion model, groundwater was identified as young water (<15 years), old water with negligible CFC-12 and 3H, and binary mixtures of the two. Model calculations using dispersion models and binary mixing based on 3H and CFC-12 concentrations demonstrate a non-atmospheric excess of SF6 relative to CFC-12 and 3H concentrations for more than half of the samples. The non-atmospheric excess SF6 may have originated from terrigenic sources in relict volcanic fluids, which could have acquired SF6 from granites and basement rocks of the island during volcanic activity. Local excess anthropogenic sources of SF6 are unlikely. The SF6 age is biased young relative to the CFC-12 age, typically up to 20 years and as high as 30 years. This age bias is more pronounced in samples of groundwater older than 15 years. The presence of terrigenic SF6 can affect the entire dating range for groundwater in mixtures that contain a fraction of old water.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5841827','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5841827"><span>Compositional shifts in root-associated bacterial and archaeal microbiota track the plant life cycle in field-grown rice</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Edwards, Joseph A.; Santos-Medellín, Christian M.; Liechty, Zachary S.; Nguyen, Bao; Lurie, Eugene; Eason, Shane; Phillips, Gregory</p> <p>2018-01-01</p> <p>Bacterial communities associated with roots impact the health and nutrition of the host plant. The dynamics of these microbial assemblies over the plant life cycle are, however, not well understood. Here, we use dense temporal sampling of 1,510 samples from root spatial compartments to characterize the bacterial and archaeal components of the root-associated microbiota of field grown rice (Oryza sativa) over the course of 3 consecutive growing seasons, as well as 2 sites in diverse geographic regions. The root microbiota was found to be highly dynamic during the vegetative phase of plant growth and then stabilized compositionally for the remainder of the life cycle. Bacterial and archaeal taxa conserved between field sites were defined as predictive features of rice plant age by modeling using a random forest approach. The age-prediction models revealed that drought-stressed plants have developmentally immature microbiota compared to unstressed plants. Further, by using genotypes with varying developmental rates, we show that shifts in the microbiome are correlated with rates of developmental transitions rather than age alone, such that different microbiota compositions reflect juvenile and adult life stages. These results suggest a model for successional dynamics of the root-associated microbiota over the plant life cycle. PMID:29474469</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29474469','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29474469"><span>Compositional shifts in root-associated bacterial and archaeal microbiota track the plant life cycle in field-grown rice.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Edwards, Joseph A; Santos-Medellín, Christian M; Liechty, Zachary S; Nguyen, Bao; Lurie, Eugene; Eason, Shane; Phillips, Gregory; Sundaresan, Venkatesan</p> <p>2018-02-01</p> <p>Bacterial communities associated with roots impact the health and nutrition of the host plant. The dynamics of these microbial assemblies over the plant life cycle are, however, not well understood. Here, we use dense temporal sampling of 1,510 samples from root spatial compartments to characterize the bacterial and archaeal components of the root-associated microbiota of field grown rice (Oryza sativa) over the course of 3 consecutive growing seasons, as well as 2 sites in diverse geographic regions. The root microbiota was found to be highly dynamic during the vegetative phase of plant growth and then stabilized compositionally for the remainder of the life cycle. Bacterial and archaeal taxa conserved between field sites were defined as predictive features of rice plant age by modeling using a random forest approach. The age-prediction models revealed that drought-stressed plants have developmentally immature microbiota compared to unstressed plants. Further, by using genotypes with varying developmental rates, we show that shifts in the microbiome are correlated with rates of developmental transitions rather than age alone, such that different microbiota compositions reflect juvenile and adult life stages. These results suggest a model for successional dynamics of the root-associated microbiota over the plant life cycle.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28150391','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28150391"><span>Around the world, adolescence is a time of heightened sensation seeking and immature self-regulation.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Steinberg, Laurence; Icenogle, Grace; Shulman, Elizabeth P; Breiner, Kaitlyn; Chein, Jason; Bacchini, Dario; Chang, Lei; Chaudhary, Nandita; Giunta, Laura Di; Dodge, Kenneth A; Fanti, Kostas A; Lansford, Jennifer E; Malone, Patrick S; Oburu, Paul; Pastorelli, Concetta; Skinner, Ann T; Sorbring, Emma; Tapanya, Sombat; Tirado, Liliana Maria Uribe; Alampay, Liane Peña; Al-Hassan, Suha M; Takash, Hanan M S</p> <p>2018-03-01</p> <p>The dual systems model of adolescent risk-taking portrays the period as one characterized by a combination of heightened sensation seeking and still-maturing self-regulation, but most tests of this model have been conducted in the United States or Western Europe. In the present study, these propositions are tested in an international sample of more than 5000 individuals between ages 10 and 30 years from 11 countries in Africa, Asia, Europe and the Americas, using a multi-method test battery that includes both self-report and performance-based measures of both constructs. Consistent with the dual systems model, sensation seeking increased between preadolescence and late adolescence, peaked at age 19, and declined thereafter, whereas self-regulation increased steadily from preadolescence into young adulthood, reaching a plateau between ages 23 and 26. Although there were some variations in the magnitude of the observed age trends, the developmental patterns were largely similar across countries. © 2017 John Wiley & Sons Ltd.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21480718','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21480718"><span>On the specificity of face cognition compared with general cognitive functioning across adult age.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hildebrandt, Andrea; Wilhelm, Oliver; Schmiedek, Florian; Herzmann, Grit; Sommer, Werner</p> <p>2011-09-01</p> <p>Face cognition is considered a specific human ability, clearly differentiable from general cognitive functioning. Its specificity is primarily supported by cognitive-experimental and neuroimaging research, but recently also from an individual differences perspective. However, no comprehensive behavioral data are available, which would allow estimating lifespan changes of the covariance structure of face-cognition abilities and general cognitive functioning as well as age-differences in face cognition after accounting for interindividual variability in general cognition. The present study aimed to fill this gap. In an age-heterogeneous (18-82 years) sample of 448 adults, we found no factorial dedifferentiation between face cognition and general cognition. Age-related differences in face memory were still salient after taking into account changes in general cognitive functioning. Face cognition thus remains a specific human ability compared with general cognition, even until old age. We discuss implications for models of cognitive aging and suggest that it is necessary to include more explicitly special social abilities in those models.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70033827','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70033827"><span>Survival of European mouflon (Artiodactyla: Bovidae) in Hawai'i based on tooth cementum lines</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Hess, S.C.; Stephens, R.M.; Thompson, T.L.; Danner, R.M.; Kawakami, B.</p> <p>2011-01-01</p> <p>Reliable techniques for estimating age of ungulates are necessary to determine population parameters such as age structure and survival. Techniques that rely on dentition, horn, and facial patterns have limited utility for European mouflon sheep (Ovis gmelini musimon), but tooth cementum lines may offer a useful alternative. Cementum lines may not be reliable outside temperate regions, however, because lack of seasonality in diet may affect annulus formation. We evaluated the utility of tooth cementum lines for estimating age of mouflon in Hawai'i in comparison to dentition. Cementum lines were present in mouflon from Mauna Loa, island of Hawai'i, but were less distinct than in North American sheep. The two age-estimation methods provided similar estimates for individuals aged ???3 yr by dentition (the maximum age estimable by dentition), with exact matches in 51% (18/35) of individuals, and an average difference of 0.8 yr (range 04). Estimates of age from cementum lines were higher than those from dentition in 40% (14/35) and lower in 9% (3/35) of individuals. Discrepancies in age estimates between techniques and between paired tooth samples estimated by cementum lines were related to certainty categories assigned by the clarity of cementum lines, reinforcing the importance of collecting a sufficient number of samples to compensate for samples of lower quality, which in our experience, comprised approximately 22% of teeth. Cementum lines appear to provide relatively accurate age estimates for mouflon in Hawai'i, allow estimating age beyond 3 yr, and they offer more precise estimates than tooth eruption patterns. After constructing an age distribution, we estimated annual survival with a log-linear model to be 0.596 (95% CI 0.5540.642) for this heavily controlled population. ?? 2011 by University of Hawai'i Press.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26308158','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26308158"><span>Aging Versus Postmenopausal Osteoporosis: Bone Composition and Maturation Kinetics at Actively-Forming Trabecular Surfaces of Female Subjects Aged 1 to 84 Years.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Paschalis, Eleftherios P; Fratzl, Peter; Gamsjaeger, Sonja; Hassler, Norbert; Brozek, Wolfgang; Eriksen, Erik F; Rauch, Frank; Glorieux, Francis H; Shane, Elizabeth; Dempster, David; Cohen, Adi; Recker, Robert; Klaushofer, Klaus</p> <p>2016-02-01</p> <p>Bone strength depends on the amount of bone, typically expressed as bone mineral density (BMD), determined by dual-energy X-ray absorptiometry (DXA), and on bone quality. Bone quality is a multifactorial entity including bone structural and material compositional properties. The purpose of the present study was to examine whether bone material composition properties at actively-forming trabecular bone surfaces in health are dependent on subject age, and to contrast them with postmenopausal osteoporosis patients. To achieve this, we analyzed by Raman microspectroscopy iliac crest biopsy samples from healthy subjects aged 1.5 to 45.7 years, paired biopsy samples from females before and immediately after menopause aged 46.7 to 53.6 years, and biopsy samples from placebo-treated postmenopausal osteoporotic patients aged 66 to 84 years. The monitored parameters were as follows: the mineral/matrix ratio; the mineral maturity/crystallinity (MMC); nanoporosity; the glycosaminoglycan (GAG) content; the lipid content; and the pyridinoline (Pyd) content. The results indicate that these bone quality parameters in healthy, actively-forming trabecular bone surfaces are dependent on subject age at constant tissue age, suggesting that with advancing age the kinetics of maturation (either accumulation, or posttranslational modifications, or both) change. For most parameters, the extrapolation of models fitted to the individual age dependence of bone in healthy individuals was in rough agreement with their values in postmenopausal osteoporotic patients, except for MMC, lipid, and Pyd content. Among these three, Pyd content showed the greatest deviation between healthy aging and disease, highlighting its potential to be used as a discriminating factor. © 2015 American Society for Bone and Mineral Research.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25942470','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25942470"><span>Gender, coping strategies, homelessness stressors, and income generation among homeless young adults in three cities.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ferguson, Kristin M; Bender, Kimberly; Thompson, Sanna J</p> <p>2015-06-01</p> <p>This study examined gender differences among homeless young adults' coping strategies and homelessness stressors as they relate to legal (e.g., full-time employment, selling personal possessions, selling blood/plasma) and illegal economic activity (e.g., selling drugs, theft, prostitution). A sample of 601 homeless young adults was recruited from 3 cities (Los Angeles, CA [n = 200], Austin, TX [n = 200], and Denver, CO [n = 201]) to participate in semi-structured interviews from March 2010 to July 2011. Risk and resilience correlates of legal and illegal economic activity were analyzed using six Ordinary Least Squares regression models with the full sample and with the female and male sub-samples. In the full sample, three variables (i.e., avoidant coping, problem-focused coping, and mania) were associated with legal income generation whereas eight variables (i.e., social coping, age, arrest history, transience, peer substance use, antisocial personality disorder [ASPD], substance use disorder [SUD], and major depressive episode [MDE]) were associated with illegal economic activity. In the female sub-sample, three variables (i.e., problem-focused coping, race/ethnicity, and transience) were correlated with legal income generation whereas six variables (i.e., problem-focused coping, social coping, age, arrest history, peer substance use, and ASPD) were correlated with illegal economic activity. Among males, the model depicting legal income generation was not significant yet seven variables (i.e., social coping, age, transience, peer substance use, ASPD, SUD, and MDE) were associated with illegal economic activity. Understanding gender differences in coping strategies and economic activity might help customize interventions aimed at safe and legal income generation for this population. Copyright © 2015 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/5152433-temporal-helium-isotopic-variations-within-hawaiian-volcanoes-basalts-from-mauna-loa-haleakala','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/5152433-temporal-helium-isotopic-variations-within-hawaiian-volcanoes-basalts-from-mauna-loa-haleakala"><span></span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Kurz, M.D.; O'Brien, P.A.; Garcia, M.O.</p> <p></p> <p>Helium isotope ratios in basalts spanning the subaerial eruptive history of Mauna Loa and Haleakala vary systematically with eruption age. In both volcanoes, olivine mineral separates from the oldest samples have the highest {sup 3}He/{sup 4}he ratios. The Haleakala samples studied range in age from roughly one million years to historic time, while the Mauna Loa samples are radiocarbon dated flows younger than 30,000 years old. The Honomanu tholeiites are the oldest samples from Haleakala and have {sup 3}He/{sup 4}he ratios that range from 13 to 16.8X atmospheric, while the younger Kula and Hana series alkali basalts all have {supmore » 3}He/{sup 4}He close to 8X atmospheric. A similar range is observed on Manua Loa; the oldest samples have {sup 3}He/{sup 4}He ratios of 15 to 20X atmospheric, with a relatively smooth decrease to 8X atmospheric with decreasing age. The consistent trend of decreasing {sup 3}He/{sup 4}he ratio with time in both volcanoes, coherence between the helium and Sr and Nd isotopes (for Haleakala), and the similarity of {sup 3}He/{sup 4}He in the late stage basalts to depleted mid-ocean ridge basalt (MORB) helium, argue against the decrease being the result of radiogenic ingrowth of {sup 4}He. The data strongly suggest an undegassed mantle source for the early shield building stages of Hawaiian volcanism, and are consistent with the hotspot/mantle plume model. The data are difficult to reconcile with models for Hawaiian volcanism that require recycled oceanic crust or derivation from a MORB-related upper mantle source. The authors interpret the decrease in {sup 3}He/{sup 4}He with volcano evolution to result from an increasing involvement of depleted mantle and/or lithosphere during the late stages of Hawaiian volcanism.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.usgs.gov/sir/2007/5088/','USGSPUBS'); return false;" href="https://pubs.usgs.gov/sir/2007/5088/"><span>Ground-Water Age and Quality in the High Plains Aquifer near Seward, Nebraska, 2003-04</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Stanton, Jennifer S.; Landon, Matthew K.; Turco, Michael J.</p> <p>2007-01-01</p> <p>The U.S. Geological Survey, in cooperation with the City of Seward, Nebraska, conducted a study of ground-water age and quality to improve understanding of: (1) traveltimes from recharge areas to public-supply wells, (2) the effects of geochemical reactions in the aquifer on water quality, and (3) how water quality has changed historically in response to land-use practices. Samples were collected from four supply wells in the Seward west well field and from nine monitoring wells along two approximate ground-water flow paths leading to the well field. Concentrations of three different chlorofluorocarbons (CFC-12, CFC-11, and CFC-113), sulfur hexafluoride (SF6), and ratios of tritium (3H) to helium-3 (3He) isotope derived from radioactive decay of 3H were used to determine the apparent recharge age of ground-water samples. Age interpretations were based primarily on 3H/3He and CFC-12 data. Estimates of apparent ground-water age from tracer data were complicated by mixing of water of different ages in 10 of the 13 ground-water samples collected. Apparent recharge dates of unmixed ground-water samples or mean recharge dates of young fractions of mixed water in samples collected from monitoring wells ranged from 1985 to 2002. For monitoring-well samples containing mixed water, the fraction of the sample composed of young water ranged from 26 to 77 percent of the sample. Apparent mean recharge dates of young fractions in samples collected from four supply wells in the Seward west well field ranged from about 1980 to 1990. Estimated fractions of the samples composed of young water ranged from 39 to 54 percent. It is implicit in the mixing calculations that the remainder of the sample that is not young water is composed of water that is more than 60 years old and contains no detectable quantities of modern atmospheric tracers. Estimated fractions of the mixed samples composed of 'old' water ranged from 23 to 74 percent. Although alternative mixing models can be used to interpret the results, the mean age and mixing fractions from the primary mixing models used were fairly similar. Relations of ground-water age and nitrate concentrations to depth were not consistent across the study area. In some well nests, more young water and nitrate were present near the bottom than in the middle of the aquifer. These results probably reflect pumping from irrigation and supply wells, which are screened primarily in the lower part of the aquifer, and draw younger water downward in the aquifer. Substantial mixing probably occurs because the aquifer is relatively thin (50 feet) and has a relatively high density of wells (about five pumping wells per square mile). The most reliable estimate of horizontal traveltimes based on differences in ground-water ages between a shallow monitoring well at the upgradient end of the northwest well transect and the deep well at the downgradient end of the well transect was 9 years to travel a distance of about 2 miles. The general similarity of ages at similar depths between different well nests is consistent with the fact that horizontal flow in the aquifer is relatively rapid. Concentrations of nitrate (as nitrogen) in untreated ground-water samples from supply wells in the well field were larger than the U.S. Environmental Protection Agency Maximum Contaminant Level for drinking water of 10 mg/L (milligrams per liter), ranging from 11.3 to 13.5 mg/L. It is unlikely that nitrate concentrations in the aquifer near the Seward west well field are decreased by denitrification in the aquifer due to oxic geochemical conditions that preclude this reaction. Nitrate concentrations coupled with water recharge dates were compared to historical estimated fertilizer application in an attempt to reconstruct historical trends in ground-water nitrate concentrations and their relation to land-use practices. Nitrate concentrations in young-water fractions, after adjustment for mixing, may be decreasing over apparent recharg</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28374100','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28374100"><span>How old is this bird? The age distribution under some phase sampling schemes.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hautphenne, Sophie; Massaro, Melanie; Taylor, Peter</p> <p>2017-12-01</p> <p>In this paper, we use a finite-state continuous-time Markov chain with one absorbing state to model an individual's lifetime. Under this model, the time of death follows a phase-type distribution, and the transient states of the Markov chain are known as phases. We then attempt to provide an answer to the simple question "What is the conditional age distribution of the individual, given its current phase"? We show that the answer depends on how we interpret the question, and in particular, on the phase observation scheme under consideration. We then apply our results to the computation of the age pyramid for the endangered Chatham Island black robin Petroica traversi during the monitoring period 2007-2014.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/17567396','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/17567396"><span>The predictors and consequences of adolescent amphetamine use: findings from the Victoria Adolescent Health Cohort Study.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Degenhardt, Louisa; Coffey, Carolyn; Moran, Paul; Carlin, John B; Patton, George C</p> <p>2007-07-01</p> <p>Previous work has highlighted the adverse consequences of early-onset cannabis use. However, little is known about the predictors and effects of early-onset amphetamine use. We set out to examine these issues using a representative cohort of young people followed-up over 11 years in Victoria, Australia. A stratified, random sample of 1943 adolescents was recruited from secondary schools across Victoria at age 14-15 years. This cohort was interviewed on eight occasions until the age of 24-25 years (78% follow-up at that age). Cross-sectional associations were assessed using logistic regression with allowance for repeated measures. Both proportional hazards models and logistic regression models were used to assess prospective associations. Approximately 7% of the sample had used amphetamines by the age of 17 years. Amphetamine use by this age was associated with poorer mental health and other drug use. The incidence of amphetamine use during the teenage years was predicted by heavier drug use and by mental health problems. By young adulthood (age 24-25 years), adolescent amphetamine users were more likely to meet criteria for dependence upon a range of drugs, to have greater psychological morbidity and to have some limitations in educational attainment. Most of these associations were not sustained after adjustment for early-onset cannabis use. Young people in Australia who begin amphetamine use by age 17 years are at increased risk for a range of mental health, substance use and psychosocial problems in young adulthood. However, these problems are largely accounted for by their even earlier-onset cannabis use.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.usgs.gov/sir/2011/5235/','USGSPUBS'); return false;" href="https://pubs.usgs.gov/sir/2011/5235/"><span>Groundwater flow, quality (2007-10), and mixing in the Wind Cave National Park area, South Dakota</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Long, Andrew J.; Ohms, Marc J.; McKaskey, Jonathan D.R.G.</p> <p>2012-01-01</p> <p>A study of groundwater flow, quality, and mixing in relation to Wind Cave National Park in western South Dakota was conducted during 2007-11 by the U.S. Geological Survey in cooperation with the National Park Service because of water-quality concerns and to determine possible sources of groundwater contamination in the Wind Cave National Park area. A large area surrounding Wind Cave National Park was included in this study because to understand groundwater in the park, a general understanding of groundwater in the surrounding southern Black Hills is necessary. Three aquifers are of particular importance for this purpose: the Minnelusa, Madison, and Precambrian aquifers. Multivariate methods applied to hydrochemical data, consisting of principal component analysis (PCA), cluster analysis, and an end-member mixing model, were applied to characterize groundwater flow and mixing. This provided a way to assess characteristics important for groundwater quality, including the differentiation of hydrogeologic domains within the study area, sources of groundwater to these domains, and groundwater mixing within these domains. Groundwater and surface-water samples collected for this study were analyzed for common ions (calcium, magnesium, sodium, bicarbonate, chloride, silica, and sulfate), arsenic, stable isotopes of oxygen and hydrogen, specific conductance, and pH. These 12 variables were used in all multivariate methods. A total of 100 samples were collected from 60 sites from 2007 to 2010 and included stream sinks, cave drip, cave water bodies, springs, and wells. In previous approaches that combined PCA with end-member mixing, extreme-value samples identified by PCA typically were assumed to represent end members. In this study, end members were not assumed to have been sampled but rather were estimated and constrained by prior hydrologic knowledge. Also, the end-member mixing model was quantified in relation to hydrogeologic domains, which focuses model results on major hydrologic processes. Finally, conservative tracers were weighted preferentially in model calibration, which distributed model errors of optimized values, or residuals, more appropriately than would otherwise be the case The latter item also provides an estimate of the relative effect of geochemical evolution along flow paths in comparison to mixing. The end-member mixing model estimated that Wind Cave sites received 38 percent of their groundwater inflow from local surface recharge, 34 percent from the upgradient Precambrian aquifer, 26 percent from surface recharge to the west, and 2 percent from regional flow. Artesian springs primarily received water from end members assumed to represent regional groundwater flow. Groundwater samples were collected and analyzed for chlorofluorocarbons, dissolved gasses (argon, carbon dioxide, methane, nitrogen, and oxygen), and tritium at selected sites and used to estimate groundwater age. Apparent ages, or model ages, for the Madison aquifer in the study area indicate that groundwater closest to surface recharge areas is youngest, with increasing age in a downgradient direction toward deeper parts of the aquifer. Arsenic concentrations in samples collected for this study ranged from 0.28 to 37.1 micrograms per liter (μg/L) with a median value of 6.4 μg/L, and 32 percent of these exceeded 10 μg/L. The highest arsenic concentrations in and near the study area are approximately coincident with the outcrop of the Minnelusa Formation and likely originated from arsenic in shale layers in this formation. Sample concentrations of nitrate plus nitrite were less than 2 milligrams per liter for 92 percent of samples collected, which is not a concern for drinking-water quality. Water samples were collected in the park and analyzed for five trace metals (chromium, copper, lithium, vanadium, and zinc), the concentrations of which did not correlate with arsenic. Dye tracing indicated hydraulic connection between three water bodies in Wind Cave.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1998ApJ...505..315C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1998ApJ...505..315C"><span>Neutron Star Population Dynamics. II. Three-dimensional Space Velocities of Young Pulsars</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Cordes, J. M.; Chernoff, David F.</p> <p>1998-09-01</p> <p>We use astrometric, distance, and spindown data on pulsars to (1) estimate three-dimensional velocity components, birth distances from the Galactic plane, and ages of individual objects; (2) determine the distribution of space velocities and the scale height of pulsar progenitors; (3) test spindown laws for pulsars; (4) test for correlations between space velocities and other pulsar parameters; and (5) place empirical requirements on mechanisms than can produce high-velocity neutron stars. Our approach incorporates measurement errors, uncertainties in distances, deceleration in the Galactic potential, and differential Galactic rotation. We focus on a sample of proper motion measurements of young (<10 Myr) pulsars whose trajectories may be accurately and simply modeled. This sample of 49 pulsars excludes millisecond pulsars and other objects that may have undergone accretion-driven spinup. We estimate velocity components and birth z distance on a case-by-case basis assuming that the actual age equals the conventional spindown age for a braking index n = 3, no torque decay, and birth periods much shorter than present-day periods. Every sample member could have originated within 0.3 kpc of the Galactic plane while still having reasonable present-day peculiar radial velocities. For the 49 object sample, the scale height of the progenitors is ~0.13 kpc, and the three-dimensional velocities are distributed in two components with characteristic speeds of 175+19-24 km s-1 and 700+300-132 km s-1, representing ~86% and ~14% of the population, respectively. The sample velocities are inconsistent with a single-component Gaussian model and are well described by a two-component Gaussian model but do not require models of additional complexity. From the best-fit distribution, we estimate that about 20% of the known pulsars will escape the Galaxy, assuming an escape speed of 500 km s-1. The best-fit, dual-component model, if augmented by an additional, low-velocity (<50 km s-1) component, tolerates, at most, only a small extra contribution in number, less than 5%. The best three-component models do not show a preference for filling in the probability distribution at speeds intermediate to 175 and 700 km s-1 but are nearly degenerate with the best two-component models. We estimate that the high-velocity tail (>1000 km s-1) may be underrepresented (in the observed sample) by a factor ~2.3 owing to selection effects in pulsar surveys. The estimates of scale height and velocity parameters are insensitive to the explicit relation of chronological and spindown ages. A further analysis starting from our inferred velocity distribution allows us to test spindown laws and age estimates. There exist comparably good descriptions of the data involving different combinations of braking index and torque decay timescale. We find that a braking index of 2.5 is favored if torque decay occurs on a timescale of ~3 Myr, while braking indices ~4.5 +/- 0.5 are preferred if there is no torque decay. For the sample as a whole, the most probable chronological ages are typically smaller than conventional spindown ages by factors as large as 2. We have also searched for correlations between three-dimensional speeds of individual pulsars and combinations of spin period and period derivative. None appears to be significant. We argue that correlations identified previously between velocity and (apparent) magnetic moment reflect the different evolutionary paths taken by young, isolated (nonbinary), high-field pulsars and older, low-field pulsars that have undergone accretion-driven spinup. We conclude that any such correlation measures differences in spin and velocity selection in the evolution of the two populations and is not a measure of processes taking place in the core collapse that produces neutron stars in the first place. We assess mechanisms for producing high-velocity neutron stars, including disruption of binary systems by symmetric supernovae and neutrino, baryonic, or electromagnetic rocket effects during or shortly after the supernova. The largest velocities seen (~1600 km s-1), along with the paucity of low-velocity pulsars, suggest that disruption of binaries by symmetric explosions is insufficient. Rocket effects appear to be a necessary and general phenomenon. The required kick amplitudes and the absence of a magnetic field-velocity correlation do not yet rule out any of the rocket models. However, the required amplitudes suggest that the core collapse process in a supernova is highly dynamic and aspherical and that the impulse delivered to the neutron star is larger than existing simulations of core collapse have achieved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014JPhG...41g5106B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014JPhG...41g5106B"><span>Forward-backward multiplicity correlation in high-energy nucleus-nucleus interactions at a few AGeV/c</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Bhattacharyya, Swarnapratim; Haiduc, Maria; Neagu, Alina Tania; Firu, Elena</p> <p>2014-07-01</p> <p>We have presented a systematic study of two-particle rapidity correlations in terms of investigating the dynamical fluctuation observable \\sigma _c^2 in the forward-backward pseudo-rapidity windows by analyzing the experimental data of {}_{}^{16} O{--}AgBr interactions at 4.5 AGeV/c, {}_{}^{22} Ne{--}AgBr interactions at 4.1 AGeV/c, {}_{}^{28} Si{--}AgBr and {}_{}^{32} S{--}AgBr interactions at 4.5 AGeV/c. The experimental results have been compared with the results obtained from the analysis of event sample simulated (MC-RAND) by generating random numbers and also with the analysis of events generated by the UrQMD and AMPT model. Our study confirms the presence of strong short-range correlations among the produced particles in the forward and the backward pseudo-rapidity region. The analysis of the simple Monte Carlo-simulated (MC-RAND) events signifies that the observed correlations are not due to mere statistics only; explanation of such correlations can be attributed to the presence of dynamical fluctuations during the production of charged pions. Comparisons of the experimental results with the results obtained from analyzing the UrQMD data sample indicate that the UrQMD model cannot reproduce the experimental findings. The AMPT model also cannot explain the experimental results satisfactorily. Comparisons of our experimental results with the results obtained from the analysis of higher energy emulsion data and with the results of the RHIC data have also been presented.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29460211','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29460211"><span>Validation of a Social Networks and Support Measurement Tool for Use in International Aging Research: The International Mobility in Aging Study.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ahmed, Tamer; Belanger, Emmanuelle; Vafaei, Afshin; Koné, Georges K; Alvarado, Beatriz; Béland, François; Zunzunegui, Maria Victoria</p> <p>2018-03-01</p> <p>The purpose of this study was to develop and validate a new instrument to assess social networks and social support (IMIAS-SNSS) for different types of social ties in an international sample of older adults. The study sample included n = 1995 community dwelling older people aged between 65 and 74 years from the baseline of the longitudinal International Mobility in Aging Study (IMIAS). In order to measure social networks for each type of social tie, participants were asked about the number of contacts, the number of contacts they see at least once a month or have a very good relationship with, or speak with at least once a month. For social support, participants had to rate the level of social support provided by the four types of contacts for five Likert scale items. Confirmatory Factor Analysis was conducted to determine the goodness of fit of the measurement models. Satisfactory goodness-of-fit indices confirmed the satisfactory factorial structure of the IMIAS-SNSS instrument. Reliability coefficients were 0.80, 0.81, 0.85, and 0.88 for friends, children, family, and partner models, respectively. The models were confirmed by CFA for each type of social tie. Moreover, IMIAS-SNSS detected gender differences in the older adult populations of IMIAS. These results provide evidence supporting that IMIAS-SNSS is a psychometrically sound instrument and of its validity and reliability for international populations of older adults.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li class="active"><span>24</span></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_24 --> <div id="page_25" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li class="active"><span>25</span></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="481"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2483311','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2483311"><span>Multilevel analysis of hepatitis A infection in children and adolescents: a household survey in the Northeast and Central-west regions of Brazil</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>de Alencar Ximenes, Ricardo Arraes; Martelli, Celina Maria Turchi; Merchán-Hamann, Edgar; Montarroyos, Ulisses Ramos; Braga, Maria Cynthia; de Lima, Maria Luíza Carvalho; Cardoso, Maria Regina Alves; Turchi, Marília Dalva; Costa, Marcelo Abrahão; de Alencar, Luiz Cláudio Arraes; Moreira, Regina Célia; Figueiredo, Gerusa Maria; Pereira, Leila Maria Moreira Beltrão</p> <p>2008-01-01</p> <p>Background The objectives were to estimate the prevalence of hepatitis A among children and adolescents from the Northeast and Midwest regions and the Federal District of Brazil and to identify individual-, household- and area-levels factors associated with hepatitis A infection. Methods This population-based survey was conducted in 2004–2005 and covered individuals aged between 5 and 19 years. A stratified multistage cluster sampling technique with probability proportional to size was used to select 1937 individuals aged between 5 and 19 years living in the Federal capital and in the State capitals of 12 states in the study regions. The sample was stratified according to age (5–9 and 10- to 19-years-old) and capital within each region. Individual- and household-level data were collected by interview at the home of the individual. Variables related to the area were retrieved from census tract data. The outcome was total antibodies to hepatitis A virus detected using commercial EIA. The age distribution of the susceptible population was estimated using a simple catalytic model. The associations between HAV infection and independent variables were assessed using the odds ratio and corrected for the random design effect and sampling weight. Multilevel analysis was performed by GLLAMM using Stata 9.2. Results The prevalence of hepatitis A infection in the 5–9 and 10–19 age-group was 41.5 and 57.4%, respectively for the Northeast, 32.3 and 56.0%, respectively for the Midwest and 33.8 and 65.1% for the Federal District. A trend for the prevalence of HAV infection to increase according to age was detected in all sites. By the age of 5, 31.5% of the children had already been infected with HAV in the Northeast region compared with 20.0% in the other sites. By the age of 19 years, seropositivity was ∼70% in all areas. The curves of susceptible populations differed from one area to another. Multilevel modeling showed that variables relating to different levels of education were associated with HAV infection in all sites. Conclusion The study sites were classified as areas with intermediate endemicity area for hepatitis A infection. Differences in age trends of infection were detected among settings. This multilevel model allowed for quantification of contextual predictors of hepatitis A infection in urban areas. PMID:18653514</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70026230','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70026230"><span>Preparation and certification of Re-Os dating reference materials: Molybdenites HLP and JDC</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Du, A.; Wu, S.; Sun, D.; Wang, Shaoming; Qu, W.; Markey, R.; Stain, H.; Morgan, J.; Malinovskiy, D.</p> <p>2004-01-01</p> <p>Two Re-Os dating reference material molybdenites were prepared. Molybdenite JDC and molybdenite HLP are from a carbonate vein-type molybdenum-(lead)- uranium deposit in the Jinduicheng-Huanglongpu area of Shaanxi province, China. The samples proved to be homogeneous, based on the coefficient of variation of analytical results and an analysis of variance test. The sampling weight was 0.1 g for JDC and 0.025 g for HLP. An isotope dilution method was used for the determination of Re and Os. Sample decomposition and preconcentration of Re and Os prior to measurement were accomplished using a variety of methods: acid digestion, alkali fusion, ion exchange and solvent extraction. Negative thermal ionisation mass spectrometry and inductively coupled plasma-mass spectrometry were used for the determination of Re and 187Os concentration and isotope ratios. The certified values include the contents of Re and Os and the model ages. For HLP, the Re content was 283.8 ?? 6.2 ??g g-1, 187Os was 659 ?? 14 ng g-1 and the Re-Os model age was 221.4 ?? 5.6 Ma. For JDC, the Re content was 17.39 ?? 0.32 ng g-1, 187Os was 25.46 ?? 0.60 ng g-1 and the Re-Os model age was 139.6 ?? 3.8 Ma. Uncertainties for both certified reference materials are stated at the 95% level of confidence. Three laboratories (from three countries: P.R. China, USA, Sweden) joined in the certification programme. These certified reference materials are primarily useful for Re-Os dating of molybdenite, sulfides, black shale, etc.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5815765','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5815765"><span>Associations between height and blood pressure in the United States population</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Bourgeois, Brianna; Watts, Krista; Thomas, Diana M.; Carmichael, Owen; Hu, Frank B.; Heo, Moonseong; Hall, John E.; Heymsfield, Steven B.</p> <p>2017-01-01</p> <p>Abstract The mechanisms linking short stature with an increase in cardiovascular and cerebrovascular disease risk remain elusive. This study tested the hypothesis that significant associations are present between height and blood pressure in a representative sample of the US adult population. Participants were 12,988 men and women from a multiethnic sample (age ≥ 18 years) evaluated in the 1999 to 2006 National Health and Nutrition Examination Survey who were not taking antihypertensive medications and who had complete height, weight, % body fat, and systolic and diastolic arterial blood pressure (SBP and DBP) measurements; mean arterial blood pressure and pulse pressure (MBP and PP) were calculated. Multiple regression models for men and women were developed with each blood pressure as dependent variable and height, age, race/ethnicity, body mass index, % body fat, socioeconomic status, activity level, and smoking history as potential independent variables. Greater height was associated with significantly lower SBP and PP, and higher DBP (all P < .001) in combined race/ethnic–sex group models beginning in the 4th decade. Predicted blood pressure differences between people who are short and tall increased thereafter with greater age except for MBP. Socioeconomic status, activity level, and smoking history did not consistently contribute to blood pressure prediction models. Height-associated blood pressure effects were present in US adults who appeared in the 4th decade and increased in magnitude with greater age thereafter. These observations, in the largest and most diverse population sample evaluated to date, provide support for postulated mechanisms linking adult stature with cardiovascular and cerebrovascular disease risk. PMID:29390353</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2005AGUFMPP14B..06E','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2005AGUFMPP14B..06E"><span>Progress in tropical isotope dendroclimatology</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Evans, M. N.; Schrag, D. P.; Poussart, P. F.; Anchukaitis, K. J.</p> <p>2005-12-01</p> <p>The terrestrial tropics remain an important gap in the growing high resolution proxy network used to characterize the mean state and variability of the hydrological cycle. Here we review early efforts to develop a new class of proxy paleorainfall/humidity indicators using intraseasonal to interannual-resolution stable isotope data from tropical trees. The approach invokes a recently published model of oxygen isotopic composition of alpha-cellulose, rapid methods for cellulose extraction from raw wood, and continuous flow isotope ratio mass spectrometry to develop proxy chronological, rainfall and growth rate estimates from tropical trees, even those lacking annual rings. Isotopically-derived age models may be confirmed for modern intervals using trees of known age, radiocarbon measurements, direct measurements of tree diameter, and time series replication. Studies are now underway at a number of laboratories on samples from Costa Rica, northwestern coastal Peru, Indonesia, Thailand, New Guinea, Paraguay, Brazil, India, and the South American Altiplano. Improved sample extraction chemistry and online pyrolysis techniques should increase sample throughput, precision, and time series replication. Statistical calibration together with simple forward modeling based on the well-observed modern period can provide for objective interpretation of the data. Ultimately, replicated data series with well-defined uncertainties can be entered into multiproxy efforts to define aspects of tropical hydrological variability associated with ENSO, the meridional overturning circulation, and the monsoon systems.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23347073','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23347073"><span>Development of the Thai healthy aging model: A grounded theory study.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Thiamwong, Ladda; McManus, Michael S; Suwanno, Jom</p> <p>2013-06-01</p> <p>To develop a model of healthy aging from the perspective of Thais, a grounded theory approach, including in-depth interviews and focus groups, was used. A purposive sample of 39 community-dwelling adults aged 40-85 years old was interviewed. The Thai healthy aging model composed of three themes: normality, nature, and dharma. In Thai, they are called tham-ma-da, tham-ma-chat, and tham-ma, or "Thai 3Ts". The theme of normality encompasses subthemes of staying physically active by being involved in plenty of physical activities, and being mentally active with creative and thoughtful hobbies and work. The theme of nature encompasses subthemes of living simply and being careful with money. The theme of dharma encompasses subthemes of enjoyment through helping family and participating in community activities, staying away from stress and worries by talking openly and honestly with someone, making merit, and helping other people without expecting anything in return. A greater understanding of healthy aging is a benefit for older adults and healthcare providers in an intervention-design process. Research can contribute valuable information to shape policy for healthy aging as well. © 2013 Wiley Publishing Asia Pty Ltd.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/16266754','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/16266754"><span>Lifespan development of pro- and anti-saccades: multiple regression models for point estimates.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Klein, Christoph; Foerster, Friedrich; Hartnegg, Klaus; Fischer, Burkhart</p> <p>2005-12-07</p> <p>The comparative study of anti- and pro-saccade task performance contributes to our functional understanding of the frontal lobes, their alterations in psychiatric or neurological populations, and their changes during the life span. In the present study, we apply regression analysis to model life span developmental effects on various pro- and anti-saccade task parameters, using data of a non-representative sample of 327 participants aged 9 to 88 years. Development up to the age of about 27 years was dominated by curvilinear rather than linear effects of age. Furthermore, the largest developmental differences were found for intra-subject variability measures and the anti-saccade task parameters. Ageing, by contrast, had the shape of a global linear decline of the investigated saccade functions, lacking the differential effects of age observed during development. While these results do support the assumption that frontal lobe functions can be distinguished from other functions by their strong and protracted development, they do not confirm the assumption of disproportionate deterioration of frontal lobe functions with ageing. We finally show that the regression models applied here to quantify life span developmental effects can also be used for individual predictions in applied research contexts or clinical practice.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013AGUFMEP53A0765O','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013AGUFMEP53A0765O"><span>Linear diffusion model dating of cinder cones in Central Anatolia, Turkey</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>O'Sadnick, L. G.; Reid, M. R.; Cline, M. L.; Cosca, M. A.; Kuscu, G.</p> <p>2013-12-01</p> <p>The progressive decrease in slope angle, cone height and cone height/width ratio over time provides the basis for geomorphic dating of cinder cones using linear diffusion models. Previous research using diffusion models to date cinder cones has focused on the cone height/width ratio as the basis for dating cones of unknown age [1,2]. Here we apply linear diffusion models to dating cinder cones. A suite of 16 cinder cones from the Hasandağ volcano area of the Neogene-Quaternary Central Anatolian Volcanic Zone, for which samples are available, were selected for morphologic dating analysis. New 40Ar/39Ar dates for five of these cones range from 62 × 4 to 517 × 9 ka. Linear diffusion models were used to model the erosional degradation of each cone. Diffusion coefficients (κ) for the 5 cinder cones with known ages were constrained by comparing various modeled slope profiles to the current slope profile. The resulting κ is 7.5×0.5 m2kyr-1. Using this κ value, eruption ages were modeled for the remaining 11 cinder cones and range from 53×3 to 455×30 ka. These ages are within the range of ages previously reported for cinder cones in the Hasandağ region. The linear diffusion model-derived ages are being compared to additional new 40Ar/39Ar dates in order to further assess the applicability of morphological dating to constrain the ages of cinder cones. The relatively well-constrained κ value we obtained by applying the linear diffusion model to cinder cones that range in age by nearly 500 ka suggests that this model can be used to date cinder cones. This κ value is higher than the well-established value of κ =3.9 for a cinder cone in a similar climate [3]. Therefore our work confirms the importance of determining appropriate κ values from nearby cones with known ages. References 1. C.A. Wood, J. Volcanol. Geotherm. Res. 8, 137 (1980) 2. D.M. Wood, M.F. Sheridan, J. Volcanol. Geotherm. Res. 83, 241 (1998) 3. J.D. Pelletier, M.L. Cline, Geology 35, 1067 (2007)</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5626504','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5626504"><span>Estimating the prevalence and intensity of Schistosoma mansoni infection among rural communities in Western Tanzania: The influence of sampling strategy and statistical approach</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Bakuza, Jared S.; Denwood, Matthew J.; Nkwengulila, Gamba</p> <p>2017-01-01</p> <p>Background Schistosoma mansoni is a parasite of major public health importance in developing countries, where it causes a neglected tropical disease known as intestinal schistosomiasis. However, the distribution of the parasite within many endemic regions is currently unknown, which hinders effective control. The purpose of this study was to characterize the prevalence and intensity of infection of S. mansoni in a remote area of western Tanzania. Methodology/Principal findings Stool samples were collected from 192 children and 147 adults residing in Gombe National Park and four nearby villages. Children were actively sampled in local schools, and adults were sampled passively by voluntary presentation at the local health clinics. The two datasets were therefore analysed separately. Faecal worm egg count (FWEC) data were analysed using negative binomial and zero-inflated negative binomial (ZINB) models with explanatory variables of site, sex, and age. The ZINB models indicated that a substantial proportion of the observed zero FWEC reflected a failure to detect eggs in truly infected individuals, meaning that the estimated true prevalence was much higher than the apparent prevalence as calculated based on the simple proportion of non-zero FWEC. For the passively sampled data from adults, the data were consistent with close to 100% true prevalence of infection. Both the prevalence and intensity of infection differed significantly between sites, but there were no significant associations with sex or age. Conclusions/Significance Overall, our data suggest a more widespread distribution of S. mansoni in this part of Tanzania than was previously thought. The apparent prevalence estimates substantially under-estimated the true prevalence as determined by the ZINB models, and the two types of sampling strategies also resulted in differing conclusions regarding prevalence of infection. We therefore recommend that future surveillance programmes designed to assess risk factors should use active sampling whenever possible, in order to avoid the self-selection bias associated with passive sampling. PMID:28934206</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5443462','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5443462"><span>Analysis of Milk from Mothers Who Delivered Prematurely Reveals Few Changes in Proteases and Protease Inhibitors across Gestational Age at Birth and Infant Postnatal Age123</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Demers-Mathieu, Veronique; Nielsen, Søren Drud; Underwood, Mark A; Borghese, Robyn</p> <p>2017-01-01</p> <p>Background: Peptidomics research has demonstrated that protease activity is higher in breast milk from preterm-delivering mothers than from term-delivering mothers. However, to our knowledge, the effect of the degree of prematurity and postnatal age on proteases and protease inhibitors in human milk remains unknown. Objective: We aimed to determine the change of proteases and protease inhibitors in milk from mothers who delivered prematurely across gestational age (GA) and postnatal age. Methods: Milk samples were collected from 18 mothers aged 26–40 y who delivered preterm infants and who lacked mastitis. For analysis, samples were separated into 2 groups: 9 from early GA (EGA) (24–26 wk GA)-delivering mothers and 9 from late GA (LGA) (27–32 wk GA)-delivering mothers. Within the 9 samples in each group, the collection time ranged from postnatal days 2 to 47. The activity and predicted activity of proteases in preterm milk were determined with the use of fluorometric and spectrophotometric assays and peptidomics, respectively. Protease and protease inhibitor concentrations were determined with the use of ELISA. Linear mixed models were applied to compare enzymes across GA and postnatal age. Results: Carboxypeptidase B2, kallikrein, plasmin, elastase, thrombin, and cytosol aminopeptidase were present and active in the milk of preterm-delivering mothers. Most milk protease and antiprotease concentrations did not change with GA or postnatal age. However, the concentration and activity of kallikrein, the most abundant and active protease in preterm milk, increased by 25.4 ng · mL−1 · d−1 and 0.454 μg · mL−1 · d−1 postnatally, respectively, in EGA milk samples while remaining stable in LGA milk samples. Conclusions: This research demonstrates that proteases are active in human milk and begin to degrade milk protein within the mammary gland before consumption by infants. Proteases and protease inhibitors in milk from mothers of premature infants mostly did not vary substantially across GA and postnatal age. PMID:28424255</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28424255','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28424255"><span>Analysis of Milk from Mothers Who Delivered Prematurely Reveals Few Changes in Proteases and Protease Inhibitors across Gestational Age at Birth and Infant Postnatal Age.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Demers-Mathieu, Veronique; Nielsen, Søren Drud; Underwood, Mark A; Borghese, Robyn; Dallas, David C</p> <p>2017-06-01</p> <p>Background: Peptidomics research has demonstrated that protease activity is higher in breast milk from preterm-delivering mothers than from term-delivering mothers. However, to our knowledge, the effect of the degree of prematurity and postnatal age on proteases and protease inhibitors in human milk remains unknown. Objective: We aimed to determine the change of proteases and protease inhibitors in milk from mothers who delivered prematurely across gestational age (GA) and postnatal age. Methods: Milk samples were collected from 18 mothers aged 26-40 y who delivered preterm infants and who lacked mastitis. For analysis, samples were separated into 2 groups: 9 from early GA (EGA) (24-26 wk GA)-delivering mothers and 9 from late GA (LGA) (27-32 wk GA)-delivering mothers. Within the 9 samples in each group, the collection time ranged from postnatal days 2 to 47. The activity and predicted activity of proteases in preterm milk were determined with the use of fluorometric and spectrophotometric assays and peptidomics, respectively. Protease and protease inhibitor concentrations were determined with the use of ELISA. Linear mixed models were applied to compare enzymes across GA and postnatal age. Results: Carboxypeptidase B2, kallikrein, plasmin, elastase, thrombin, and cytosol aminopeptidase were present and active in the milk of preterm-delivering mothers. Most milk protease and antiprotease concentrations did not change with GA or postnatal age. However, the concentration and activity of kallikrein, the most abundant and active protease in preterm milk, increased by 25.4 ng · mL -1 · d -1 and 0.454 μg · mL -1 · d -1 postnatally, respectively, in EGA milk samples while remaining stable in LGA milk samples. Conclusions: This research demonstrates that proteases are active in human milk and begin to degrade milk protein within the mammary gland before consumption by infants. Proteases and protease inhibitors in milk from mothers of premature infants mostly did not vary substantially across GA and postnatal age. © 2017 American Society for Nutrition.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=peer+AND+pressure+OR+peer+AND+influence&pg=6&id=EJ992186','ERIC'); return false;" href="https://eric.ed.gov/?q=peer+AND+pressure+OR+peer+AND+influence&pg=6&id=EJ992186"><span>The Role of Individual Correlates and Class Norms in Defending and Passive Bystanding Behavior in Bullying: A Multilevel Analysis</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Pozzoli, Tiziana; Gini, Gianluca; Vieno, Alessio</p> <p>2012-01-01</p> <p>This study investigates possible individual and class correlates of defending and passive bystanding behavior in bullying, in a sample of 1,825 Italian primary school (mean age = 10 years 1 month) and middle school (mean age = 13 years 2 months) students. The findings of a series of multilevel regression models show that both individual (e.g.,…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.fs.usda.gov/treesearch/pubs/46656','TREESEARCH'); return false;" href="https://www.fs.usda.gov/treesearch/pubs/46656"><span>Management implications of long-term tree growth and mortality rates: A modeling study of big-leaf mahogany (Swietenia macrophylla) in the Brazilian Amazon</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.fs.usda.gov/treesearch/">Treesearch</a></p> <p>C.M. Free; R.M. Landis; J. Grogan; M.D. Schulze; M. Lentini; O. Dunisch; NO-VALUE</p> <p>2014-01-01</p> <p>Knowledge of tree age-size relationships is essential towards evaluating the sustainability of harvest regulations that include minimum diameter cutting limits and fixed-length cutting cycles. Although many tropical trees form annual growth rings and can be aged from discs or cores, destructive sampling is not always an option for valuable or threatened species. We...</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4709545','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4709545"><span>Complement pathway biomarkers and age-related macular degeneration</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Gemenetzi, M; Lotery, A J</p> <p>2016-01-01</p> <p>In the age-related macular degeneration (AMD) ‘inflammation model', local inflammation plus complement activation contributes to the pathogenesis and progression of the disease. Multiple genetic associations have now been established correlating the risk of development or progression of AMD. Stratifying patients by their AMD genetic profile may facilitate future AMD therapeutic trials resulting in meaningful clinical trial end points with smaller sample sizes and study duration. PMID:26493033</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24828111','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24828111"><span>Potential for adult-based epidemiological studies to characterize overall cancer risks associated with a lifetime of CT scans.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Shuryak, Igor; Lubin, Jay H; Brenner, David J</p> <p>2014-06-01</p> <p>Recent epidemiological studies have suggested that radiation exposure from pediatric CT scanning is associated with small excess cancer risks. However, the majority of CT scans are performed on adults, and most radiation-induced cancers appear during middle or old age, in the same age range as background cancers. Consequently, a logical next step is to investigate the effects of CT scanning in adulthood on lifetime cancer risks by conducting adult-based, appropriately designed epidemiological studies. Here we estimate the sample size required for such studies to detect CT-associated risks. This was achieved by incorporating different age-, sex-, time- and cancer type-dependent models of radiation carcinogenesis into an in silico simulation of a population-based cohort study. This approach simulated individual histories of chest and abdominal CT exposures, deaths and cancer diagnoses. The resultant sample sizes suggest that epidemiological studies of realistically sized cohorts can detect excess lifetime cancer risks from adult CT exposures. For example, retrospective analysis of CT exposure and cancer incidence data from a population-based cohort of 0.4 to 1.3 million (depending on the carcinogenic model) CT-exposed UK adults, aged 25-65 in 1980 and followed until 2015, provides 80% power for detecting cancer risks from chest and abdominal CT scans.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25584744','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25584744"><span>Active ageing and quality of life: factors associated with participation in leisure activities among institutionalized older adults, with and without dementia.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Fernández-Mayoralas, Gloria; Rojo-Pérez, Fermina; Martínez-Martín, Pablo; Prieto-Flores, Maria-Eugenia; Rodríguez-Blázquez, Carmen; Martín-García, Salomé; Rojo-Abuín, José-Manuel; Forjaz, Maria-Joao</p> <p>2015-01-01</p> <p>Active ageing, considered from the perspective of participation in leisure activities, promotes life satisfaction and personal well-being. The aims of this work are to define and explain leisure activity profiles among institutionalized older adults, considering their sociodemographic characteristics and objective and subjective conditions in relation to their quality of life. Two samples of institutionalized people aged 60 and over were analysed together: 234 older adults without dementia and 525 with dementia. Sociodemographic, economic, family and social network, and health and functioning variables were selected. Cluster analysis was applied to obtain activity profiles according to the leisure activities, and ordinal regression models were performed to analyse factors associated to activity level. The sample was clustered into three groups of people: active (27%), moderately active (35%) and inactive people (38%). In the final regression model (Nagelkerke pseudo R(2) = 0.500), a higher level of activity was associated with better cognitive function (Pfeiffer scale), self-perceived health status and functional ability, as well as with a higher frequency of gathering with family and friends, and higher educational level. The decline in physical and mental health, the loss of functional capabilities and the weakening of family and social ties represent a significant barrier to active ageing in a context of institutionalization.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27467901','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27467901"><span>Household Food Insecurity May Predict Underweightand Wasting among Children Aged 24-59 Months.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Abdurahman, Ahmed A; Mirzaei, Khadijeh; Dorosty, Ahmed Reza; Rahimiforoushani, A; Kedir, Haji</p> <p>2016-01-01</p> <p>The aim of this study was to examine the association between household food insecurity and nutritional status among children aged 24-59 months in Haromaya District. Children (N = 453) aged 24-59 months were recruited in a community-based cross-sectional survey with a representative sample of households selected by a multistage sampling procedure in Haromaya District. Household Food Insecurity Access Scale and anthropometry were administered. Multinomial logistic regression models were applied to select variables that are candidate for multivariable model. The prevalences of stunting, underweight, and wasting among children aged 24-59 months were 61.1%, 28.1%, and 11.8%, respectively. The mean household food insecurity access scale score was 3.34, and 39.7% of households experienced some degree of food insecurity. By logistic regression analysis and after adjusting for the confounding factors, household food insecurity was significantly predictive of underweight (AOR = 2.48, CI = 1.17-5.24, p = .05) and chronic energy deficiency (AOR = 0.47, CI = 0.23-0.97, p = .04) and marginally significant for wasting (AOR = 0.53, CI = 0.27-1.03, p = .06). It is concluded that household food security improves child growth and nutritional status.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22352969','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22352969"><span>Paths from socioemotional behavior in middle childhood to personality in middle adulthood.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Pulkkinen, Lea; Kokko, Katja; Rantanen, Johanna</p> <p>2012-09-01</p> <p>Continuity in individual differences from socioemotional behavior in middle childhood to personality characteristics in middle adulthood was examined on the assumption that they share certain temperament-related elements. Socioemotional characteristics were measured using teacher ratings at ages 8 (N = 369; 53% males) and 14 (95% of the initial sample). Personality was assessed at age 42 (63% of the initial sample; 50% males) using a shortened version of the NEO Personality Inventory (NEO-PI); the Karolinska Scales of Personality (KSP); and the Adult Temperament Questionnaire (ATQ). Three models were tested using structural equation modeling. The results confirmed paths (a) from behavioral activity to adult Extraversion and Openness (NEO-PI), sociability (KSP), and surgency (ATQ); (b) from well-controlled behavior to adult conformity (KSP) and Conscientiousness (NEO-PI); and (c) from negative emotionality to adult aggression (KSP). The paths were significant only for one gender, and more frequently for males than for females. The significant male paths from behavioral activity to all indicators of adult activity and from well-controlled behavior to adult conformity started at age 8, whereas significant female paths from behavioral activity to adult sociability and from well-controlled behavior to adult Conscientiousness started at age 14. PsycINFO Database Record (c) 2012 APA, all rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22028921','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22028921"><span>Comparative analysis of old-age mortality estimations in Africa.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bendavid, Eran; Seligman, Benjamin; Kubo, Jessica</p> <p>2011-01-01</p> <p>Survival to old ages is increasing in many African countries. While demographic tools for estimating mortality up to age 60 have improved greatly, mortality patterns above age 60 rely on models based on little or no demographic data. These estimates are important for social planning and demographic projections. We provide direct estimations of older-age mortality using survey data. Since 2005, nationally representative household surveys in ten sub-Saharan countries record counts of living and recently deceased household members: Burkina Faso, Côte d'Ivoire, Ethiopia, Namibia, Nigeria, Swaziland, Tanzania, Uganda, Zambia, and Zimbabwe. After accounting for age heaping using multiple imputation, we use this information to estimate probability of death in 5-year intervals ((5)q(x)). We then compare our (5)q(x) estimates to those provided by the World Health Organization (WHO) and the United Nations Population Division (UNPD) to estimate the differences in mortality estimates, especially among individuals older than 60 years old. We obtained information on 505,827 individuals (18.4% over age 60, 1.64% deceased). WHO and UNPD mortality models match our estimates closely up to age 60 (mean difference in probability of death -1.1%). However, mortality probabilities above age 60 are lower using our estimations than either WHO or UNPD. The mean difference between our sample and the WHO is 5.9% (95% CI 3.8-7.9%) and between our sample is UNPD is 13.5% (95% CI 11.6-15.5%). Regardless of the comparator, the difference in mortality estimations rises monotonically above age 60. Mortality estimations above age 60 in ten African countries exhibit large variations depending on the method of estimation. The observed patterns suggest the possibility that survival in some African countries among adults older than age 60 is better than previously thought. Improving the quality and coverage of vital information in developing countries will become increasingly important with future reductions in mortality.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2007APS..DMP.G6009H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2007APS..DMP.G6009H"><span>Dielectric Spectroscopy Analysis of Aged EVOH films with Application to Deterioration of Food Packaging Materials</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Hoeller, Timothy</p> <p>2007-06-01</p> <p>Samples of EVOH films from compositions of 29 - 44 mol% ethylene content were exposed to thermal aging with and without light exposure. The results of Dielectric Spectroscopy on select samples showed Cole-Cole plots of skewed dielectric constant indicating multiple distributions of dipole relaxation times. The onset for decreases in dielectric response occurs earlier in samples exposed to elevated temperature under light exposure. Lower permittivity is exhibited in samples of higher ethylene content. Results from heat exposed samples are presented. Colorimetric analysis indicates only a slight film yellowing in one case. Raman spectroscopy on untreated films discerns changes in the C-C-O stretch associated with the alcohol. The effects of aging on microstructure may cause hindrance of molecular motion from moisture desorption. Slight material degradation occurs from film hardening presumably due to crosslinking. An electrical circuit model of the conduction processes associated with the EVOH films is presented. Dielectric analysis shows promise for monitoring material changes related to deterioration. We are also using these methods to understand Fluorescence Imaging which has been recently released for paper and plastic materials analysis. Future work may include refinement of these techniques for identification of changes in material properties correlated to packaging material barrier resistance.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70033944','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70033944"><span>Survival of white-tailed deer neonates in Minnesota and South Dakota</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Grovenburg, T.W.; Swanson, C.C.; Jacques, C.N.; Klaver, R.W.; Brinkman, T.J.; Burris, B.M.; Deperno, C.S.; Jenks, J.A.</p> <p>2011-01-01</p> <p>Understanding the influence of intrinsic (e.g., age, birth mass, and sex) and habitat factors on survival of neonate white-tailed deer improves understanding of population ecology. During 2002–2004, we captured and radiocollared 78 neonates in eastern South Dakota and southwestern Minnesota, of which 16 died before 1 September. Predation accounted for 80% of mortality; the remaining 20% was attributed to starvation. Canids (coyotes [Canis latrans], domestic dogs) accounted for 100% of predation on neonates. We used known fate analysis in Program MARK to estimate survival rates and investigate the influence of intrinsic and habitat variables on survival. We developed 2 a priori model sets, including intrinsic variables (model set 1) and habitat variables (model set 2; forested cover, wetlands, grasslands, and croplands). For model set 1, model {Sage-interval} had the lowest AICc (Akaike's information criterion for small sample size) value, indicating that age at mortality (3-stage age-interval: 0–2 weeks, 2–8 weeks, and >8 weeks) best explained survival. Model set 2 indicated that habitat variables did not further influence survival in the study area; β-estimates and 95% confidence intervals for habitat variables in competing models encompassed zero; thus, we excluded these models from consideration. Overall survival rate using model {Sage-interval} was 0.87 (95% CI = 0.83–0.91); 61% of mortalities occurred at 0–2 weeks of age, 26% at 2–8 weeks of age, and 13% at >8 weeks of age. Our results indicate that variables influencing survival may be area specific. Region-specific data are needed to determine influences of intrinsic and habitat variables on neonate survival before wildlife managers can determine which habitat management activities influence neonate populations.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li class="active"><span>25</span></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_25 --> <div class="footer-extlink text-muted" style="margin-bottom:1rem; text-align:center;">Some links on this page may take you to non-federal websites. 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