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Sample records for agency docket id

  1. Federal Agency Hazardous Waste Compliance Docket (docket). Revision 1

    SciTech Connect

    Not Available

    1994-01-01

    The Federal Facilities Hazardous Waste Compliance Docket (``docket``) identifies Federal facilities that may be contaminated with hazardous substances and that must be evaluated to determine if they pose a risk to public health or the environment The docket, required by Section 120(c) of the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA), as amended by the Superfund Amendments and Reauthorization Act of 1986 (SARA), also provides a vehicle for making information about potentially contaminated facilities available to the public. Facilities listed on the docket must complete site assessments that provide the Environmental Protection Agency (EPA) with information needed to determine whether or not the facility should be included on he National Priorities List (NPL). This Information Brief, which revises the previous Federal Agency Hazardous Waste Compiliance Docket Information Brief, provides updated information on the docket listing process, the implications of listing, and facility status after listing.

  2. Federal Agency Hazardous Waste Compliance Docket

    EPA Pesticide Factsheets

    List of the Federal Agency Hazardous Waste Compliance Docket Facilities comprised of four lists: National Priorities List (NPL), Non-National Priorities List, Base Realignment and Closure Act (BRAC), and Resource Conservation and Recovery Act (RCRA).

  3. Federal Agency Hazardous Waste Compliance Docket

    EPA Pesticide Factsheets

    The Federal Agency Hazardous Waste Compliance Docket contains information reported to EPA by federal facilities that manage hazardous waste or from which hazardous substances, pollutants, or contaminants have been - or may be - released.

  4. Previous Federal Agency Hazardous Waste Compliance Docket Updates

    EPA Pesticide Factsheets

    The Federal Agency Hazardous Waste Compliance Docket contains information reported to EPA by federal facilities that manage hazardous waste or from which hazardous substances, pollutants, or contaminants have been - or may be - released.

  5. 78 FR 8498 - [Docket ID DoD-2013-OS-0016

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF DEFENSE Office of the Secretary Manual for Courts-Martial; Proposed Amendments AGENCY: Joint Service Committee on Military Justice (JSC), DoD. ACTION: Annual Review of the Manual for Courts-Martial, United States....

  6. 77 FR 55486 - Agency Information Collection Activities: Importer ID Input Record

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-10

    ... SECURITY U.S. Customs and Border Protection Agency Information Collection Activities: Importer ID Input Record AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: 30-Day Notice and request for comments; Extension of an existing collection of information. SUMMARY: U.S....

  7. 76 FR 36916 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-23

    ... Request; EPA's WasteWise Program (Renewal) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice... your comments, referencing Docket ID No. EPA-HQ-RCRA- 2010-0832, to (1) EPA, either online using http://www.regulations.gov (our preferred method), or by email to rcra-docket@epa.gov , or by mail to:...

  8. 78 FR 73522 - Agency Information Collection Activities: Submission to OMB for Review and Approval; State Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-06

    ... Framework; EPA ICR Number 2185.05 AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: In..., identified by Docket ID No. EPA-HQ- OECA-2010-0291, by one of the following methods: http://www.regulations...., Washington, DC 20460. Hand Delivery: Information Center in the EPA Docket Center (EPA/DC), EPA West,...

  9. 49 CFR 601.44 - Posting to the docket.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 24 hours a day, seven days a week, via the Internet at the docket facility's Web site at http://dms... petitions for relief or comments to the docket must include the agency name (Federal Transit...

  10. 78 FR 18586 - Registration Review; Pesticide Dockets Opened for Review and Comment and Other Docket Acts

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-27

    ... AGENCY Registration Review; Pesticide Dockets Opened for Review and Comment and Other Docket Acts AGENCY... comment period for several registration reviews. Registration review is EPA's periodic review of pesticide registrations to ensure that each pesticide continues to satisfy the statutory standard for registration,...

  11. 76 FR 64957 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, Standard...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-19

    ... SECURITY Federal Emergency Management Agency Docket ID FEMA-2011-0017; OMB No. 1660-0040] Agency Information Collection Activities: Submission for OMB Review; Comment Request, Standard Flood Hazard... Emergency Management Agency (FEMA) will submit the information collection abstracted below to the Office...

  12. 77 FR 74659 - Agency Information Collection Activities; Proposed Collection; Comment Request; Oil Pollution...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-17

    ... instructions for submitting comments. (2) Email: Docket.RCRA@epa.gov , Attention Docket ID No, EPA-HQ-OPA- 2007-0584 (3) Fax: 202-566-9744, Attention Docket ID No. EPA-HQ-OPA-2007-0584 (4) Mail: EPA Docket Center.... NW., Washington, DC 20460. Attention Docket ID No. EPA-HQ-OPA-2007-0584. Such deliveries are...

  13. 40 CFR 194.67 - Dockets.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Dockets. 194.67 Section 194.67 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS CRITERIA FOR THE CERTIFICATION AND RE-CERTIFICATION OF THE WASTE ISOLATION PILOT PLANT'S COMPLIANCE WITH THE...

  14. 40 CFR 155.32 - Public docket.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... will not be included): (1) An index of its contents (refer to paragraph (c) of this section). (2) A... complete chronic health and teratology data base exists, a copy of the Federal Register notice concerning... publication of the notice). (c) Index of the docket. The Agency will establish and keep current an index...

  15. 40 CFR 155.32 - Public docket.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... will not be included): (1) An index of its contents (refer to paragraph (c) of this section). (2) A... complete chronic health and teratology data base exists, a copy of the Federal Register notice concerning... publication of the notice). (c) Index of the docket. The Agency will establish and keep current an index...

  16. 40 CFR 155.32 - Public docket.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... will not be included): (1) An index of its contents (refer to paragraph (c) of this section). (2) A... complete chronic health and teratology data base exists, a copy of the Federal Register notice concerning... publication of the notice). (c) Index of the docket. The Agency will establish and keep current an index...

  17. 40 CFR 155.32 - Public docket.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... will not be included): (1) An index of its contents (refer to paragraph (c) of this section). (2) A... complete chronic health and teratology data base exists, a copy of the Federal Register notice concerning... publication of the notice). (c) Index of the docket. The Agency will establish and keep current an index...

  18. 76 FR 74039 - Approaches to Reducing Sodium Consumption; Establishment of Dockets; Request for Comments, Data...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-30

    ... and Inspection Service Approaches to Reducing Sodium Consumption; Establishment of Dockets; Request... entitled ``Approaches to Reducing Sodium Consumption; Establishment of Dockets; Request for Comments, Data... both Agencies about current and emerging practices by the private sector regarding sodium reduction...

  19. FEDFacts: Information about the Federal Electronic Docket Facilities

    EPA Pesticide Factsheets

    Cleanup status information related to Federal Facilities contained in EPA's Federal Agency Hazardous Waste Compliance Docket. Information includes maps, lists of facilities, dashboard view with graphs, links to community resources, and news items.

  20. 76 FR 81490 - Agency Information Collection Activities; Proposed Collection; Comment Request; Contractor...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-28

    ... AGENCY Agency Information Collection Activities; Proposed Collection; Comment Request; Contractor... include a total of three (3) copies and identify the Docket ID Number EPA-HQ-OARM-2011-0997, Contractor... activity or ICR does this apply to? Affected entities: All contractors who have completed an EPA...

  1. 75 FR 76980 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-10

    ... Request; NESHAP for Beryllium (Renewal), EPA ICR Number 0193.10, OMB Control Number 2060-0092 AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: In compliance with the Paperwork Reduction Act... before January 10, 2011. ADDRESSES: Submit your comments, referencing docket ID number EPA-HQ-...

  2. 78 FR 24193 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-24

    ... Request; NESHAP for Site Remediation (Renewal), EPA ICR Number 2062.05 AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: In compliance with the Paperwork Reduction Act (44 U.S.C. 3501 et...: Submit your comments, referencing docket ID number EPA-HQ- OECA-2012-0695, to: (1) EPA online, using...

  3. 75 FR 2536 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-15

    ... Request; EPA's WaterSense Program (Renewal); EPA ICR No. 2233.04, OMB Control No. 2040-0272 AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: In compliance with the Paperwork Reduction Act... submitted on or before February 16, 2010. ADDRESSES: Submit your comments, referencing Docket ID No....

  4. 77 FR 18804 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ... Request; Focus Groups as Used By EPA for Economics Projects (Renewal) AGENCY: Environmental Protection Agency (EPA). ] ACTION: Notice. SUMMARY: In compliance with the Paperwork Reduction Act (PRA)(44 U.S.C... 27, 2012. ADDRESSES: Submit your comments, referencing Docket ID No. EPA-HQ-OA- 2008-0701, to (1)...

  5. 77 FR 5293 - Establishment of an Emergency Relief Docket for Calendar Year 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-02

    ... Federal Railroad Administration Establishment of an Emergency Relief Docket for Calendar Year 2012 AGENCY...: This Notice announces the establishment of FRA's emergency relief docket (ERD) for calendar year 2012. The designated ERD for calendar year 2012 is docket number FRA-2012-0005. ADDRESSES: See...

  6. 78 FR 3964 - Establishment of an Emergency Relief Docket for Calendar Year 2013

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-17

    ... Federal Railroad Administration Establishment of an Emergency Relief Docket for Calendar Year 2013 AGENCY...: This Notice announces the establishment of FRA's emergency relief docket (ERD) for calendar year 2013. The designated ERD for calendar year 2013 is docket number FRA-2013-0001. ADDRESSES: See...

  7. 75 FR 3782 - Establishment of an Emergency Relief Docket for Calendar Year 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-22

    ... Federal Railroad Administration Establishment of an Emergency Relief Docket for Calendar Year 2010 AGENCY...: This Notice announces the establishment of FRA's emergency relief docket (ERD) for calendar year 2010. The designated ERD for calendar year 2010 is docket number FRA-2010-0003. ADDRESSES: See...

  8. 76 FR 1209 - Establishment of an Emergency Relief Docket for Calendar Year 2011

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-07

    ... Federal Railroad Administration Establishment of an Emergency Relief Docket for Calendar Year 2011 AGENCY...: This Notice announces the establishment of FRA's emergency relief docket (ERD) for calendar year 2011. The designated ERD for calendar year 2011 is docket number FRA-2011-0003. ADDRESSES: See...

  9. 75 FR 48325 - Agency Information Collection Activities: Proposed Collection; Comment Request; Underground...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-10

    ... Storage Tanks: Technical and Financial Requirements, and State Program Approval Procedures (Renewal), EPA...: U.S. Environmental Protection Agency, EPA Docket Center, Underground Storage Tanks Docket, Mail Code... Agency, EPA Docket Center, Underground Storage Tanks Docket, 1200 Pennsylvania Avenue, NW.,...

  10. Registration Review Docket Opening Schedule

    EPA Pesticide Factsheets

    Dockets are opened on a fiscal year schedule for reevaluation of all pesticides. They are subdivided into conventional pesticides, antimicrobials, biochemicals, and microbials. The schedules for 2014 to 2017 are attached.

  11. 75 FR 38114 - [Docket ID FEMA-2010-0008

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-01

    ..., the estimated burden (i.e., the time, effort and resources used by respondents to respond) and cost... strengths and areas for improvement are identified, corrected, and shared as appropriate prior to a real.... Frequency of Response: On Occasion. Estimated Average Hour Burden per Respondent: 800 Hours. Estimated...

  12. 76 FR 72391 - Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-23

    ... [Federal Register Volume 76, Number 226 (Wednesday, November 23, 2011)] [Notices] [Page 72391] [FR Doc No: 2011-30251] DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID DOD-2011-OS-0055] Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense Logistics...

  13. 76 FR 38151 - Agency Information Collection Activities; Proposed Collection; Comment Request; Reporting and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ... Recordkeeping Requirements for Importation of Nonroad Engines and Recreational Vehicles AGENCY: Environmental... ``search,'' then key in the docket ID number identified in this document. What information is EPA... this action are importers into the United States of nonroad engines and vehicles. Title: Reporting...

  14. 76 FR 80930 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-27

    ... Request; Requirements and Exemptions for Specific RCRA Wastes (Renewal) AGENCY: Environmental Protection... January 26, 2012. ADDRESSES: Submit your comments, referencing Docket ID No. EPA-HQ-RCRA- 2011-0543, to (1) EPA, either online using http://www.regulations.gov (our preferred method), or by email to...

  15. 78 FR 16841 - Agency Information Collection Activities; Comment Request; Fiscal Operations Report for 2012-2013...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-19

    ... Application To Participate for 2014-2015 (FISAP) and Reallocation Form AGENCY: Department of Education (ED... (44 U.S.C. chapter 3501 et seq.), ED is proposing a revision of an existing information collection... Portal at http://www.regulations.gov by selecting Docket ID number ED-2013-ICCD- 0031 or via postal...

  16. 78 FR 74125 - Agency Information Collection Activities; Comment Request; Measuring Educational Gain in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-10

    ... Reporting System for Adult Education AGENCY: Department of Education (ED), Office of Vocational and Adult.... chapter 3501 et seq.), ED is proposing an extension of an existing information collection. DATES... Portal at http://www.regulations.gov by selecting Docket ID number ED-2013-ICCD- 0147 or via postal...

  17. 78 FR 60865 - Agency Information Collection Activities; Submission to the Office of Management and Budget for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ...-0001 AGENCY: Office of Postsecondary Education (OPE) Department of Education (ED). ACTION: Notice. SUMMARY: In accordance with the Paperwork Reduction Act of 1995 (44 U.S.C. chapter 3501 et seq.), ED is....regulations.gov by selecting Docket ID number ED-2013-ICCD- 0129 or via postal mail, commercial delivery,...

  18. 78 FR 77665 - Agency Information Collection Activities; Comment Request; Federal Direct Consolidation Loan...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... Application Documents AGENCY: Federal Student Aid (FSA), Department of Education (ED). ACTION: Notice. SUMMARY: In accordance with the Paperwork Reduction Act of 1995 (44 U.S.C. chapter 3501 et seq.), ED is... Docket ID number ED-2013-ICCD- 0158 or via postal mail, commercial delivery, or hand delivery....

  19. 78 FR 30900 - Agency Information Collection Activities; Submission to the Office of Management and Budget for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-23

    ... Administration (RSA) (1894-0001) AGENCY: Department of Education (ED), Office of Special Education and... (44 U.S.C. chapter 3501 et seq.), ED is proposing; an extension of an existing information collection... Portal at http://www.regulations.gov by selecting Docket ID number ED-2013-ICCD- 0068 or via postal...

  20. 78 FR 16842 - Agency Information Collection Activities; Submission to the Office of Management and Budget for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-19

    ... Education (EASIE) AGENCY: Office of Elementary and Secondary Education (OESE), Department of Education (ED... et seq.), ED is proposing an extension of an existing information collection. DATES: Interested...://www.regulations.gov by selecting Docket ID number ED-2013-ICCD- 0001 or via postal mail,...

  1. 78 FR 18576 - Agency Information Collection Activities; Comment Request; Experimental Sites Data Collection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-27

    ... AGENCY: Department of Education (ED), Federal Student Aid (FSA). ACTION: Notice. SUMMARY: In accordance with the Paperwork Reduction Act of 1995 (44 U.S.C. chapter 3501 et seq.), ED is proposing a new... Federal eRulemaking Portal at http://www.regulations.gov by selecting Docket ID number ED-2013-ICCD-...

  2. 78 FR 56868 - Agency Information Collection Activities; Comment Request; Lender's Request for Payment of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-16

    ... Special Allowance--LaRS AGENCY: Federal Student Aid (FSA), Department of Education (ED). ACTION: Notice. SUMMARY: In accordance with the Paperwork Reduction Act of 1995 (44 U.S.C. chapter 3501 et seq.), ED is... by selecting Docket ID number ED-2013-ICCD- 0123 or via postal mail, commercial delivery, or...

  3. 78 FR 60303 - Agency Information Collection Activities: Online Survey of Web Services Employers; New...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-01

    ... of Web Services Employers; New Information Collection ACTION: 30-Day Notice. SUMMARY: The Department... via the Federal eRulemaking Portal Web site at http://www.Regulations.gov under e-Docket ID number... collection. (2) Title of the Form/Collection: Online Survey of Web Services Employers. (3) Agency form...

  4. 75 FR 71430 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-23

    ... Request; Land Disposal Restrictions (Renewal), EPA ICR Number 1442.21, OMB Control Number 2050-0085 AGENCY... submitted on or before December 23, 2010. ADDRESSES: Submit your comments, referencing Docket ID No. EPA-HQ-RCRA- 2010-0512, to (1) EPA, either online using www.regulations.gov (our preferred method), or by...

  5. 78 FR 77122 - Registration Review; Pesticide Dockets Opened for Review and Comment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-20

    ... AGENCY Registration Review; Pesticide Dockets Opened for Review and Comment AGENCY: Environmental... period for several registration reviews. Registration review is EPA's periodic review of pesticide registrations to ensure that each pesticide continues to satisfy the statutory standard for registration,...

  6. Procedures for Electronic Management of Rulemaking and Other Docketed Records in the Federal Docket Management System

    EPA Pesticide Factsheets

    This procedure identifies the specific requirements, processes and supporting documents EPA uses to electronically manage rulemaking and other docketed records in the Federal Docket Management System (FDMS).

  7. 75 FR 70029 - Notice of Temporary Closure of Castle Rocks Inter-Agency Recreation Area in Cassia County, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-16

    ... Bureau of Land Management Notice of Temporary Closure of Castle Rocks Inter-Agency Recreation Area in... camping, and the construction of new trails is in effect on public lands within the Castle Rocks Inter... the BLM at Castle Rocks Inter-Agency Recreation Area in Cassia County, Idaho. Lands in the...

  8. 78 FR 16824 - Tobacco Product Manufacturing Practice; Establishment of a Public Docket

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-19

    ... HUMAN SERVICES Food and Drug Administration 21 CFR Chapter I Tobacco Product Manufacturing Practice; Establishment of a Public Docket AGENCY: Food and Drug Administration, HHS. ACTION: Establishment of a public docket; request for comments. SUMMARY: The Food and Drug Administration (FDA) is establishing a...

  9. 44 CFR 1.5 - Rules docket.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... records and which are a part of a specific rulemaking procedure, including but not limited to, advance... docket is established, any person may examine docketed material at any time during established hours of business and may obtain a copy of any docketed material upon payment of the prescribed fee. (See part 5...

  10. 10 CFR 110.102 - Hearing docket.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Hearing docket. 110.102 Section 110.102 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) EXPORT AND IMPORT OF NUCLEAR EQUIPMENT AND MATERIAL Hearings § 110.102 Hearing docket. For each hearing, the Secretary will maintain a docket which will include the...

  11. 76 FR 9774 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-22

    ... mail to: EPA Docket Center, Environmental Protection Agency, Water Docket, Mailcode 28221T, 1200... viewing at the Water Docket in the EPA Docket Center (EPA/DC), EPA West, Room 3334, 1301 Constitution Ave... the telephone number for the Water Docket is 202-566-2426. Use EPA's electronic docket and...

  12. 78 FR 60868 - Amendment of the Federal Docket Management System (EPA/GOV-2)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... AGENCY Amendment of the Federal Docket Management System (EPA/GOV-2) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: Pursuant to the provisions of the Privacy Act of 1974 (5 USC 552a), the Environmental Protection Agency (EPA) is giving notice that it is amending the Federal...

  13. 78 FR 38328 - Registration Review; Pesticide Dockets Opened for Review and Comment; Announcement of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ... AGENCY Registration Review; Pesticide Dockets Opened for Review and Comment; Announcement of Registration... EPA's periodic review of pesticide registrations to ensure that each pesticide continues to satisfy the statutory standard for registration, that is, the pesticide can perform its intended...

  14. 78 FR 3454 - Prairie Island, Independent Spent Fuel Storage Installation; Notice of Docketing of Amendment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-16

    ... COMMISSION Prairie Island, Independent Spent Fuel Storage Installation; Notice of Docketing of Amendment... Considerations and Containing Sensitive Unclassified Non-Safeguards Information AGENCY: Nuclear Regulatory... CFR), who believes access to Sensitive Unclassified Non-Safeguards Information (SUNSI) is necessary...

  15. 78 FR 56947 - Prairie Island; Independent Spent Fuel Storage Installation; Notice of Docketing of Amendment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-16

    ... COMMISSION Prairie Island; Independent Spent Fuel Storage Installation; Notice of Docketing of Amendment... Information AGENCY: Nuclear Regulatory Commission. ACTION: License amendment request; opportunity to request a... spent fuel storage installation located in Welch, Minnesota. DATES: Requests for a hearing or...

  16. 75 FR 2163 - Constellation Energy; Notice of Docketing of Special Nuclear Material License SNM-2505 Amendment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-14

    ... COMMISSION Constellation Energy; Notice of Docketing of Special Nuclear Material License SNM-2505 Amendment Application for the Calvert Cliffs Independent Spent Fuel Storage Installation AGENCY: Nuclear Regulatory..., Project Manager, Licensing Branch, Division of Spent Fuel Storage and Transportation, Office of...

  17. 7 CFR 1781.17 - Docket preparation and processing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Docket preparation and processing. 1781.17 Section...) LOANS AND ADVANCES § 1781.17 Docket preparation and processing. (a) Loan dockets. Dockets for WS loans... of this chapter. (1) Time for preparation of docket. Docket preparation may begin as soon as...

  18. 7 CFR 1781.17 - Docket preparation and processing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 12 2014-01-01 2013-01-01 true Docket preparation and processing. 1781.17 Section...) LOANS AND ADVANCES § 1781.17 Docket preparation and processing. (a) Loan dockets. Dockets for WS loans... of this chapter. (1) Time for preparation of docket. Docket preparation may begin as soon as...

  19. 7 CFR 1781.17 - Docket preparation and processing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 12 2013-01-01 2013-01-01 false Docket preparation and processing. 1781.17 Section...) LOANS AND ADVANCES § 1781.17 Docket preparation and processing. (a) Loan dockets. Dockets for WS loans... of this chapter. (1) Time for preparation of docket. Docket preparation may begin as soon as...

  20. 76 FR 52992 - Notice of Acceptance for Docketing of the Application and Notice of Opportunity for Hearing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-24

    ...-issued digital ID certificate). Based upon this information, the Secretary will establish an electronic... docket. Information about applying for a digital ID certificate is available on NRC's public Web site at... sufficient information in accordance with 10 CFR 54.19, 54.21, 54.22, 54.23, 51.45, and 51.53(c), to...

  1. 7 CFR 1944.412 - Docket preparation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 13 2010-01-01 2009-01-01 true Docket preparation. 1944.412 Section 1944.412 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... preparation. When the application and all items required for the complete docket have been received,...

  2. 7 CFR 1944.412 - Docket preparation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 13 2011-01-01 2009-01-01 true Docket preparation. 1944.412 Section 1944.412 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... preparation. When the application and all items required for the complete docket have been received,...

  3. 7 CFR 1944.412 - Docket preparation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 13 2014-01-01 2013-01-01 true Docket preparation. 1944.412 Section 1944.412 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... preparation. When the application and all items required for the complete docket have been received,...

  4. 7 CFR 1944.412 - Docket preparation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 13 2013-01-01 2013-01-01 false Docket preparation. 1944.412 Section 1944.412 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... preparation. When the application and all items required for the complete docket have been received,...

  5. 7 CFR 1944.412 - Docket preparation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 13 2012-01-01 2012-01-01 false Docket preparation. 1944.412 Section 1944.412 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... preparation. When the application and all items required for the complete docket have been received,...

  6. 22 CFR 102.27 - Docket.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Docket. 102.27 Section 102.27 Foreign Relations DEPARTMENT OF STATE ECONOMIC AND OTHER FUNCTIONS CIVIL AVIATION Recommendations to the President Under Section 801 of the Federal Aviation Act of 1958 § 102.27 Docket. (a) All comments submitted under...

  7. 49 CFR 553.5 - Regulatory docket.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Regulatory docket. 553.5 Section 553.5 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY... under § 553.25; and final rules are maintained in the Docket Room, National Highway Traffic...

  8. 49 CFR 511.48 - Official docket.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Official docket. 511.48 Section 511.48 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ADJUDICATIVE PROCEDURES Hearings § 511.48 Official docket. (a)...

  9. 10 CFR 590.106 - Dockets.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Dockets. 590.106 Section 590.106 Energy DEPARTMENT OF ENERGY (CONTINUED) NATURAL GAS (ECONOMIC REGULATORY ADMINISTRATION) ADMINISTRATIVE PROCEDURES WITH RESPECT TO THE IMPORT AND EXPORT OF NATURAL GAS General Provisions § 590.106 Dockets. The FE...

  10. 10 CFR 590.106 - Dockets.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Dockets. 590.106 Section 590.106 Energy DEPARTMENT OF ENERGY (CONTINUED) NATURAL GAS (ECONOMIC REGULATORY ADMINISTRATION) ADMINISTRATIVE PROCEDURES WITH RESPECT TO THE IMPORT AND EXPORT OF NATURAL GAS General Provisions § 590.106 Dockets. The FE...

  11. 10 CFR 590.106 - Dockets.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Dockets. 590.106 Section 590.106 Energy DEPARTMENT OF ENERGY (CONTINUED) NATURAL GAS (ECONOMIC REGULATORY ADMINISTRATION) ADMINISTRATIVE PROCEDURES WITH RESPECT TO THE IMPORT AND EXPORT OF NATURAL GAS General Provisions § 590.106 Dockets. The FE...

  12. 10 CFR 590.106 - Dockets.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Dockets. 590.106 Section 590.106 Energy DEPARTMENT OF ENERGY (CONTINUED) NATURAL GAS (ECONOMIC REGULATORY ADMINISTRATION) ADMINISTRATIVE PROCEDURES WITH RESPECT TO THE IMPORT AND EXPORT OF NATURAL GAS General Provisions § 590.106 Dockets. The FE...

  13. 10 CFR 590.106 - Dockets.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Dockets. 590.106 Section 590.106 Energy DEPARTMENT OF ENERGY (CONTINUED) NATURAL GAS (ECONOMIC REGULATORY ADMINISTRATION) ADMINISTRATIVE PROCEDURES WITH RESPECT TO THE IMPORT AND EXPORT OF NATURAL GAS General Provisions § 590.106 Dockets. The FE...

  14. 10 CFR 820.10 - Office of the docketing clerk.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Office of the docketing clerk. 820.10 Section 820.10 Energy DEPARTMENT OF ENERGY PROCEDURAL RULES FOR DOE NUCLEAR ACTIVITIES General § 820.10 Office of the docketing clerk. (a) Docket. The Docketing Clerk shall maintain a docket for enforcement actions...

  15. 10 CFR 820.10 - Office of the docketing clerk.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Office of the docketing clerk. 820.10 Section 820.10 Energy DEPARTMENT OF ENERGY PROCEDURAL RULES FOR DOE NUCLEAR ACTIVITIES General § 820.10 Office of the docketing clerk. (a) Docket. The Docketing Clerk shall maintain a docket for enforcement actions...

  16. 10 CFR 820.10 - Office of the docketing clerk.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Office of the docketing clerk. 820.10 Section 820.10 Energy DEPARTMENT OF ENERGY PROCEDURAL RULES FOR DOE NUCLEAR ACTIVITIES General § 820.10 Office of the docketing clerk. (a) Docket. The Docketing Clerk shall maintain a docket for enforcement actions...

  17. 10 CFR 820.10 - Office of the docketing clerk.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Office of the docketing clerk. 820.10 Section 820.10 Energy DEPARTMENT OF ENERGY PROCEDURAL RULES FOR DOE NUCLEAR ACTIVITIES General § 820.10 Office of the docketing clerk. (a) Docket. The Docketing Clerk shall maintain a docket for enforcement actions...

  18. 10 CFR 820.10 - Office of the docketing clerk.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Office of the docketing clerk. 820.10 Section 820.10 Energy DEPARTMENT OF ENERGY PROCEDURAL RULES FOR DOE NUCLEAR ACTIVITIES General § 820.10 Office of the docketing clerk. (a) Docket. The Docketing Clerk shall maintain a docket for enforcement actions...

  19. 78 FR 41803 - Establishment of a Public Docket for Comment on the Report Prepared Under the Food and Drug...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-11

    ... HUMAN SERVICES Food and Drug Administration Establishment of a Public Docket for Comment on the Report Prepared Under the Food and Drug Administration Safety and Innovation Act Section 1138 AGENCY: Food and Drug Administration, HHS. ACTION: Establishment of docket; request for comments. SUMMARY: The Food...

  20. 75 FR 26751 - Agency Information Collection Activities; Proposed Collection; Comment Request; Internet Survey...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-12

    ... 20460, Attention Docket ID No. EPA-HQ-OAR- 2009-0865. Hand Delivery: Docket Center, (EPA/DC) EPA West, Room B102, 1301 Constitution Ave., NW., Washington, DC, Attention Docket ID No. EPA-HQ-OAR-2009-0865... appropriate automated electronic, mechanical, or other technological collection techniques or other forms...

  1. 75 FR 67713 - Agency Information Collection Activities; Proposed Collection; Comment Request; National...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-03

    ... comments. E-mail: ow-docket@epa.gov . Mail: EPA Docket Center, Water Docket, Environmental Protection... Headquarters, Office of Water, Office of Wastewater Management, Mailcode 4203M, Environmental Protection Agency... at the Water Docket in the EPA Docket Center (EPA/DC), EPA West, Room 3334, 1301 Constitution...

  2. 49 CFR 389.5 - Regulatory docket.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS RULEMAKING PROCEDURES-FEDERAL MOTOR CARRIER SAFETY REGULATIONS General § 389.5 Regulatory docket. (a) Information and...

  3. 77 FR 59188 - Registration Review; Pesticide Dockets Opened for Review and Comment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-26

    ... environmental effects from exposure to the pesticide(s) discussed in this document, compared to the general... AGENCY Registration Review; Pesticide Dockets Opened for Review and Comment AGENCY: Environmental... registration reviews. Registration review is EPA's periodic review of pesticide registrations to ensure...

  4. 75 FR 60119 - Registration Review; Antimicrobial Pesticide Dockets Opened for Review and Comment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-29

    ... AGENCY Registration Review; Antimicrobial Pesticide Dockets Opened for Review and Comment AGENCY... for the pesticides listed in the table in Unit III.A. With this document, EPA is opening the public comment period for these registration reviews. Registration review is EPA's periodic review of...

  5. 39 CFR 3001.13 - Docket and hearing calendar.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... documents filed in a docket, other than matter filed under seal, and the hearing calendar may be accessed... 39 Postal Service 1 2010-07-01 2010-07-01 false Docket and hearing calendar. 3001.13 Section 3001... General Applicability § 3001.13 Docket and hearing calendar. The Secretary shall maintain a docket of...

  6. 24 CFR 10.4 - Rules docket.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Rules docket. 10.4 Section 10.4 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development... Housing and Urban Development, 451 7th Street, SW., Washington, DC 20410. All public rulemaking...

  7. Social Science Docket, 2000-2001.

    ERIC Educational Resources Information Center

    Singer, Alan, Ed.

    2001-01-01

    A joint publication of the New York and New Jersey State Councils for the Social Studies, "Social Science Docket" presents K-12 teachers with resources covering the social science disciplines, including history, economics, political science, sociology, geography, anthropology, and psychology. Each issue includes theme-related and…

  8. 75 FR 57782 - Registration Review; Pesticide Dockets Opened for Review and Comment; Amended Work Plan for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ... AGENCY Registration Review; Pesticide Dockets Opened for Review and Comment; Amended Work Plan for... pesticide's registration is based on ] current scientific and other knowledge, including its effects on... announcing the availability of an amended final work plan for the registration review of the...

  9. 78 FR 11268 - Notice of Establishment of Emergency Relief Docket for Calendar Year 2013

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-15

    ... Federal Transit Administration Notice of Establishment of Emergency Relief Docket for Calendar Year 2013 AGENCY: Federal Transit Administration (FTA), DOT. ACTION: Notice SUMMARY: The Federal Transit... Division, Office of Chief Counsel, Federal Transit Administration, 1200 New Jersey Ave. S.E., Room...

  10. 77 FR 5088 - Notice of Establishment of Emergency Relief Docket for Calendar Year 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ... Federal Transit Administration Notice of Establishment of Emergency Relief Docket for Calendar Year 2012 AGENCY: Federal Transit Administration (FTA), DOT. ACTION: Notice. SUMMARY: The Federal Transit..., Federal Transit Administration, 1200 New Jersey Ave. SE., Room E56-306, Washington, DC, 20590, phone:...

  11. 75 FR 5639 - Notice of Establishment of Emergency Relief Docket for Calendar Year 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-03

    ... Federal Transit Administration Notice of Establishment of Emergency Relief Docket for Calendar Year 2010 AGENCY: Federal Transit Administration (FTA), DOT. ACTION: Notice. SUMMARY: The Federal Transit... Counsel, Federal Transit Administration, 1200 New Jersey Ave., SE., Room E56-308, Washington, DC...

  12. 10 CFR 2.643 - Acceptance and docketing of application for limited work authorization.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... acceptable for processing, the Director of New Reactors or the Director of Nuclear Reactor Regulation will... 10 Energy 1 2013-01-01 2013-01-01 false Acceptance and docketing of application for limited work authorization. 2.643 Section 2.643 Energy NUCLEAR REGULATORY COMMISSION AGENCY RULES OF PRACTICE AND...

  13. 77 FR 24487 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-24

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION... Request; Voluntary Aluminum Industrial Partnership (VAIP) (Renewal) AGENCY: Environmental Protection... to: EPA Docket Center, Environmental Protection Agency, Air and Radiation Docket Information...

  14. 39 CFR 3001.13 - Docket and hearing calendar.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 39 Postal Service 1 2012-07-01 2012-07-01 false Docket and hearing calendar. 3001.13 Section 3001... General Applicability § 3001.13 Docket and hearing calendar. The Secretary shall maintain a docket of all... shall maintain a hearing calendar of all proceedings that have been set for hearing. Proceedings...

  15. 39 CFR 3001.13 - Docket and hearing calendar.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 39 Postal Service 1 2013-07-01 2013-07-01 false Docket and hearing calendar. 3001.13 Section 3001... General Applicability § 3001.13 Docket and hearing calendar. The Secretary shall maintain a docket of all... shall maintain a hearing calendar of all proceedings that have been set for hearing. Proceedings...

  16. 39 CFR 3001.13 - Docket and hearing calendar.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 39 Postal Service 1 2014-07-01 2014-07-01 false Docket and hearing calendar. 3001.13 Section 3001... General Applicability § 3001.13 Docket and hearing calendar. The Secretary shall maintain a docket of all... shall maintain a hearing calendar of all proceedings that have been set for hearing. Proceedings...

  17. 39 CFR 3001.13 - Docket and hearing calendar.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Docket and hearing calendar. 3001.13 Section 3001... General Applicability § 3001.13 Docket and hearing calendar. The Secretary shall maintain a docket of all... shall maintain a hearing calendar of all proceedings that have been set for hearing. Proceedings...

  18. 76 FR 48856 - Agency Information Collection Activities; Proposed Collection; Comment Request; Identification...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-09

    ... hazardous waste under RCRA. This ICR is scheduled to expire on January 31, 2012. Before submitting the ICR.... ADDRESSES: Submit your comments, identified by Docket ID No. EPA-HQ- RCRA-2011-0625, by one of the following...: rcra-docket@epa.gov . Fax: 202-566-9744. Mail: RCRA Docket (28221T), U.S. Environmental...

  19. 77 FR 14778 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-13

    ..., referencing docket ID number EPA-HQ- OECA-2011-0239, to: (1) EPA online using www.regulations.gov (our... number EPA-HQ-OECA-2011-0239, which is available for public viewing online at http://www.regulations.gov... Compliance Docket is (202) 566-1752. Use EPA's electronic docket and comment system at...

  20. 76 FR 60822 - Registration Review; Pesticide Dockets Opened for Review and Comment and Other Docket Actions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... review dockets for the pesticides listed in the table in Unit III.A. With this document, EPA is opening the public comment period for these registration reviews. Registration review is EPA's periodic review... the specific pesticide of interest provided in the table in Unit III.A., by one of the...

  1. 38 CFR 19.75 - Field hearing docket.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Field hearing docket. 19... Department of Veterans Affairs Field Facilities § 19.75 Field hearing docket. Hearings on appeal held at Department of Veterans Affairs field facilities will be scheduled for each area served by a regional...

  2. 38 CFR 19.75 - Field hearing docket.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Field hearing docket. 19... Department of Veterans Affairs Field Facilities § 19.75 Field hearing docket. Hearings on appeal held at Department of Veterans Affairs field facilities will be scheduled for each area served by a regional...

  3. 38 CFR 19.75 - Field hearing docket.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Field hearing docket. 19... Department of Veterans Affairs Field Facilities § 19.75 Field hearing docket. Hearings on appeal held at Department of Veterans Affairs field facilities will be scheduled for each area served by a regional...

  4. 38 CFR 19.75 - Field hearing docket.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Field hearing docket. 19... Department of Veterans Affairs Field Facilities § 19.75 Field hearing docket. Hearings on appeal held at Department of Veterans Affairs field facilities will be scheduled for each area served by a regional...

  5. 38 CFR 19.75 - Field hearing docket.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Field hearing docket. 19... Department of Veterans Affairs Field Facilities § 19.75 Field hearing docket. Hearings on appeal held at Department of Veterans Affairs field facilities will be scheduled for each area served by a regional...

  6. 10 CFR 205.15 - Public docket room.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Public docket room. 205.15 Section 205.15 Energy... room. There shall be established at the DOE National Office, 12th and Pennsylvania Avenue, NW., Washington, DC, a public docket room in which shall be made available for public inspection and copying:...

  7. 75 FR 39248 - Agency Information Collection Activities; Proposed Collection; Comment Request; Land Disposal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-08

    .../epahome/dockets.htm . FOR FURTHER INFORMATION CONTACT: Peggy Vyas, Environmental Protection Agency, 1200... address: vyas.peggy@epa.gov . SUPPLEMENTARY INFORMATION: How can I access the docket and/or...

  8. 75 FR 70254 - Typographical Error in Summary Notice of Filing in Docket for Polymerized Fatty Acid Esters With...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-17

    ... AGENCY Typographical Error in Summary Notice of Filing in Docket for Polymerized Fatty Acid Esters With...), concerning the Notice of Filing (NOF) for Pesticide Petition (PP) 0E7699 for polymerized fatty acid esters... Notice of Filing (NOF) for Pesticide Petition (PP) 0E7699 for polymerized fatty acid esters...

  9. 10 CFR 2.815 - Docketing and acceptance review.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ORDERS Rulemaking § 2.815 Docketing and acceptance review. (a) Each application for a standard design... copy of the tendered application will be available for public inspection at the NRC Web site,...

  10. 40 CFR 155.32 - Public docket.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... that one or more risk criteria set forth in 40 CFR 154.7 (leading to a special review) may have been... complete chronic health and teratology data base exists, a copy of the Federal Register notice concerning... require that persons on the list renew their requests for inclusion on the list. (3) The Agency will...

  11. 77 FR 38624 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-28

    ..., Environmental Protection Agency, Air and Radiation Docket, Mail Code 28221T, 1200 Pennsylvania Avenue NW... FURTHER INFORMATION CONTACT: Philip Egidi, Radiation Protection Division, Office of Radiation and Indoor... , or in person viewing at the Air and Radiation Docket in the EPA Docket Center (EPA/DC), EPA...

  12. 76 FR 59672 - Notice of Change In IC Docket Numbering Policy

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-27

    ... Energy Regulatory Commission Notice of Change In IC Docket Numbering Policy Notice is hereby given that the Commission is modifying the numbering system for the docket prefix IC. These IC docket notices... Commission adopted the current IC docket prefix \\1\\ in order to properly track any comments it receives...

  13. Request for Correction of Information Concerning the U.S. Environmental Protection Agency's EPAct/V2/E-89 Fuel Effects Study and Motor Vehicle Emissions Simulator Model (MOVES2014) Docket ID Nos. EPA420-R-13-002, FRL-9917-26-OAR

    EPA Pesticide Factsheets

    Petition for the US EPA to correct information concerning motor vehicle fiel emissions represented in the Motor Vehicle Emissions Simulator model (MOVES2014) and the EPAct/V2/E-89 fuel effects study (EPAct study)1 on which it is based

  14. 76 FR 44585 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-26

    ... to the Office of Management and Budget (OMB) for review and approval. This is a request to renew an... and Regulatory Affairs, Office of Management and Budget (OMB), Attention: Desk Officer for EPA, 725... electronically. Once in the system, select ``docket search,'' then key in the docket ID number identified...

  15. 77 FR 30279 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-22

    ... been forwarded to the Office of Management and Budget (OMB) for review and approval. This is a request... Information and Regulatory Affairs, Office of Management and Budget (OMB), Attention: Desk Officer for EPA..., select ``docket search,'' then key in the docket ID number identified above. Please note that...

  16. 77 FR 50499 - Agency Information Collection Activities: Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-21

    ... Office of Management and Budget (OMB) for review and approval. This is a request to renew an existing... Management and Budget (OMB), Attention: Desk Officer for EPA, 725 17th Street, NW., Washington, DC 20503. FOR... in the system, select ``docket search,'' then key in the docket ID number identified above....

  17. 76 FR 28771 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-18

    ... consolidated in 40 CFR part 9. Abstract: When EPA establishes new regulations with tighter engine emission... online using http://www.regulations.gov (our preferred method), by e-mail to a-and-r-Docket@epa.gov , or... Docket ID No. EPA-HQ-2007-0904, which is available for online viewing at http://www.regulations.gov ,...

  18. 77 FR 20689 - Agency Information Collection Activities: Request for Comments for a New Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-05

    ... identified by DOT Docket ID 2012- 0032 by any of the following methods: Web Site: For access to the docket to... Traffic Noise Model Version 3.0 Beta-Tester Information. Background: Prior to the release of the Federal Highway Administration Traffic Noise Model (FHWA TNM), the FHWA Highway Traffic Noise Prediction...

  19. The International Doris Service (IDS)

    NASA Astrophysics Data System (ADS)

    Tavernier, G.; Feissel-Vernier, M.; Lemoine, F.; Noll, C.; Ries, J.; Soudarin, L.; Willis, P.

    The DORIS system was developed for precise orbit determination and precise positioning on Earth. In continuation of the DORIS Pilot Experiment initiated in 1999, the International DORIS Service (IDS) officially started on July 1, 2003 as an IAG Service after the decision of the IAG Executive Committee at the IUGG General Assembly in Sapporo. Following this decision, the IERS Directing board accepted the DORIS Service as a new IERS external service. Six satellites fitted out with DORIS receivers are currently flying, permanently observed by 56 well distributed stations. Among them, three satellites equipped with new DORIS receivers (Jason-1, ENVISAT and SPOT5) have been successfully launched between Dec. 2001 and May 2002. All of them host a navigation function, called DIODE. Two new stations have been added to the permanent network in 2003: Crozet (French Southern Indian Ocean territories) and Jiufeng (China). In response to proposals submitted by candidate host agencies in the frame of IDS, the following stations were installed: Wettzell (Germany), Gavdos (radar altimeter calibration site in Crete), Lambert and Sorsdal (Glacier movement monitoring in Antarctica) in Winter 2001/2002, 2002/2003 and 2003/2004. The 2003 and early 2004 highlights include the renovation of a number of stations, reorganization of the Data Centers, and new developments in the coordination of analyses. While the Analysis Centers continue their support to IERS, the Analysis Coordinator and the Central Bureau are jointly developing comparison and combination activities that eventually aim at benefiting to the IERS Combination Pilot Project.

  20. 78 FR 41060 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-09

    ... Request; NSPS for Incinerators (Renewal) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice...), Environmental Protection Agency, Enforcement and Compliance Docket and Information Center, mail code 28221T..., and Media Programs Division, Office of Compliance, Mail Code 2227A, Environmental Protection...

  1. Not Another ID Model.

    ERIC Educational Resources Information Center

    Roberts, Stephanie; Conn, Cynthia; Lohr, Linda; Hunt, Erin; Duffy, Annmari

    2003-01-01

    Presents a meta-model of instructional design (ID) that integrates content covered in instructional technology graduate programs and explores the impact of an instructional designer's perspective on designs. Discusses the theoretical background; instructional strategies; educational philosophies; paradigm shifts; behaviorist, constructivist, and…

  2. 33 CFR 1.05-25 - Public docket.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....gov. To access a rulemaking, enter the docket number associated with rulemaking in the “Search” box... Commanders are available for public inspection at the appropriate Coast Guard District office or online at... available for inspection at the appropriate Captains of the Port Office or online at...

  3. 29 CFR 500.225 - Notice of docketing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Notice of docketing. 500.225 Section 500.225 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS MIGRANT AND SEASONAL AGRICULTURAL WORKER PROTECTION Administrative Proceedings Referral for Hearing § 500.225 Notice...

  4. 76 FR 4149 - Notice of Establishment of Emergency Relief Docket for Calendar Year 2011

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-24

    ... Federal Transit Administration Notice of Establishment of Emergency Relief Docket for Calendar Year 2011... Administration (FTA) is establishing an Emergency Relief Docket for calendar year 2011 so grantees and..., FTA is establishing an Emergency Relief Docket for calendar year 2011. FOR FURTHER INFORMATION...

  5. 42 CFR 426.410 - Docketing and evaluating the acceptability of LCD complaints.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 3 2011-10-01 2011-10-01 false Docketing and evaluating the acceptability of LCD... LOCAL COVERAGE DETERMINATIONS Review of an LCD § 426.410 Docketing and evaluating the acceptability of LCD complaints. (a) Docketing the complaint. The office designated by CMS does the following...

  6. 42 CFR 426.410 - Docketing and evaluating the acceptability of LCD complaints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Docketing and evaluating the acceptability of LCD... LOCAL COVERAGE DETERMINATIONS Review of an LCD § 426.410 Docketing and evaluating the acceptability of LCD complaints. (a) Docketing the complaint. The office designated by CMS does the following...

  7. 76 FR 33651 - Approval and Promulgation of Implementation Plans; ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-09

    ... AGENCY 40 CFR Part 52 Approval and Promulgation of Implementation Plans; ID AGENCY: Environmental... Implementation Plan (SIP) that were submitted to EPA by the State of Idaho on April 16, 2007. This SIP submittal... through 668. Sec. 52.670 Identification of plan. * * * * * (c) * * * EPA-Approved Idaho Regulations...

  8. 77 FR 16831 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-22

    ... Request; Federal Supplier (Small Business) Greenhouse Gas Inventory Pilot (Renewal) AGENCY: Environmental....gov , or by mail to: EPA Docket Center, Environmental Protection Agency, Air and Radiation Docket..., 725 17th Street NW., Washington, DC 20503. FOR FURTHER INFORMATION CONTACT: John Sottong,...

  9. 62 FR 28104 - Union Pacific Railroad CompanyAbandonment Exemptionin Malheur County, OR and Owyhee County, ID...

    Federal Register 2010, 2011, 2012, 2013, 2014

    1997-05-22

    ... and Owyhee County, ID (Homedale Branch) On May 2, 1997, Union Pacific Railroad Company (UP) filed with..., and Owyhee County, ID, and includes the non-agency stations of Napton, OR-- milepost 16.90;...

  10. 76 FR 61098 - Guidance for 1-Hour SO2

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-03

    ... Docket ID No. EPA-HQ- OAR-2010-1059, by one of the following methods: http://www.regulations.gov . Follow... No. EPA-HQ-OAR-2010-1059. Fax: 202-566-9744. Attention Docket ID No. EPA-HQ-OAR- 2010-1059. Mail: Air Docket, Attention Docket ID No. EPA-HQ-OAR-2010- 1059, Environmental Protection Agency, Mail Code:...

  11. 76 FR 20661 - Agency Information Collection Activities; Proposed Collection; Comment Request; Contractor...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    ... AGENCY Agency Information Collection Activities; Proposed Collection; Comment Request; Contractor... electronic docket, go to http://www.regulations.gov . Title: Contractor Conflicts of Interest. ICR numbers.... Abstract: EPA contractors will be required to disclose business relationships and corporate affiliations...

  12. 76 FR 76405 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-07

    ... Request; Water Quality Standards Regulations (Renewal) AGENCY: Environmental Protection Agency (EPA... docket, go to http://www.regulations.gov . Title: Water Quality Standards Regulation (Renewal). ICR.... Abstract: Water quality standards are provisions of State, Tribal, and Federal law that consist...

  13. 77 FR 22777 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-17

    ... Request; RCRA Expanded Public Participation (Renewal) AGENCY: Environmental Protection Agency (EPA... docket, go to www.regulations.gov . Title: RCRA Expanded Public Participation (Renewal). ICR numbers: EPA... provide for, encourage, and assist public participation in the development, revision, implementation,...

  14. 76 FR 40377 - Agency Information Collection Activities; Proposed Collection; Comment Request; Class II Special...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-08

    ... HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities; Proposed... Condoms AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug... information to the Division of Dockets Management (HFA- 305), Food and Drug Administration, 5630 Fishers...

  15. 76 FR 76401 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-07

    ... Request; NESHAP for Cellulose Products Manufacturing (Renewal) AGENCY: Environmental Protection Agency... docket, go to http://www.regulations.gov . Title: NESHAP for Cellulose Products Manufacturing (Renewal... Standards for Hazardous Air Pollutants (NESHAP), for Cellulose Products Manufacturing were proposed...

  16. IDS contribution to ITRF2008

    NASA Astrophysics Data System (ADS)

    Valette, J.; Lemoine, F.; Ferrage, P.; Altamimi, Z.; Willis, P.; Stepanek, P.; Otten, M.; Govind, R.; Kuzin, S.; Le Bail, K.; Moore, P.; Yaya, P.; Soudarin, L.

    2009-12-01

    The International DORIS Service (IDS), in operation since 2003, submitted three sets of solutions to ITRF2005 from the IGN/JPL, LEGOS/CLS, and INASAN analysis centers, but no DORIS technique combination. Since that time new analysis centers have become operational including the Geodetic Observatory Pecny (GOP), the European Space Operations Center (ESOC), Geoscience Australia (GAU), the NASA Goddard Space Flight Center (GSC), and the University of Newcastle (NCL). These analysis centers run different software, including Gypsy (IGN & INASAN), GINS (LCA), Bernese (GOP), NAPEOS (ESOC), GEODYN (Geoscience Australia and NASA GSFC) and FAUST (NCL). In order to contribute to ITRF2008, seven analysis centers processed DORIS data from TOPEX/Poseidon, SPOT2, SPOT3, SPOT4, SPOT5, and ENVISAT from 1992 to 2008, producing weekly SINEX solutions or normal equations. The weekly SINEX files from seven AC’s were processed with the CATREF software. Three iterations of an IDS weekly combined time series were completed. The IDS-1, and IDS-2 combinations were preliminary station-only solutions. In the final combination, IDS-3, both stations and the Earth Orientation Paramters (EOP’s) were adjusted. Between each of the IDS combinations, the combination strategy (station filtering, outliers, weighting, scale or geocenter contributions) was improved and the AC’s SINEX series were refined. Some series were extended in data span while others were recomputed to correct anomalies or to improve the quality of the submissions, based on feedback from the combination analyses and intercenter comparisons. For example in IDS-1, both the GAU and GSC solutions were affected by a 20 mm scale offset that was removed in IDS-2 and IDS-3 after the application of improved troposphere modelling in the GEODYN software. The analysis for IDS-1 showed a higher station position WRMS in the vicinity of the high solar flux periods (late 2001-2002). Consequently for IDS-2, several AC’s (LCA, GAU, GSC

  17. 76 FR 67196 - Approaches to Reducing Sodium Consumption; Establishment of Dockets; Request for Comments, Data...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-31

    ... Approaches to Reducing Sodium Consumption; Establishment of Dockets; Request for Comments, Data, and... of sodium, as well as current and emerging approaches designed to promote sodium reduction....

  18. 77 FR 25533 - Agency Requests for Approval of a New Information Collection(s): Human Subjects Experiments...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-30

    ... National Highway Traffic Safety Administration Agency Requests for Approval of a New Information Collection... Audible Warnings AGENCY: National Highway Traffic Safety Administration (NHTSA), Department of... regulatory efforts that contemplate revising Federal Motor Vehicle Safety Standard No. 114 (Docket No....

  19. 78 FR 59633 - Wireless Telecommunications Bureau Opens Docket To Seek Comment on DISH Network Corporation's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-27

    ... COMMISSION 47 CFR Parts 1 and 27 Wireless Telecommunications Bureau Opens Docket To Seek Comment on DISH... Docket No. 13-225 and seeks comment on a Petition for Waiver and Request for Extension of time filed by.... Pursuant to Sec. Sec. 1.3 and 1.925(b)(3)(i) of the Commission's rules, DISH seeks a waiver of Sec....

  20. 44 CFR 66.3 - Establishment of community case file and flood elevation study docket.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... case file and flood elevation study docket. 66.3 Section 66.3 Emergency Management and Assistance... National Flood Insurance Program CONSULTATION WITH LOCAL OFFICIALS § 66.3 Establishment of community case file and flood elevation study docket. (a) A file shall be established for each community at the...

  1. 44 CFR 66.3 - Establishment of community case file and flood elevation study docket.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... case file and flood elevation study docket. 66.3 Section 66.3 Emergency Management and Assistance... National Flood Insurance Program CONSULTATION WITH LOCAL OFFICIALS § 66.3 Establishment of community case file and flood elevation study docket. (a) A file shall be established for each community at the...

  2. 44 CFR 67.3 - Establishment and maintenance of a flood elevation determination docket (FEDD).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... of a flood elevation determination docket (FEDD). 67.3 Section 67.3 Emergency Management and... MITIGATION National Flood Insurance Program APPEALS FROM PROPOSED FLOOD ELEVATION DETERMINATIONS § 67.3 Establishment and maintenance of a flood elevation determination docket (FEDD). The Federal...

  3. 44 CFR 67.3 - Establishment and maintenance of a flood elevation determination docket (FEDD).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... of a flood elevation determination docket (FEDD). 67.3 Section 67.3 Emergency Management and... MITIGATION National Flood Insurance Program APPEALS FROM PROPOSED FLOOD ELEVATION DETERMINATIONS § 67.3 Establishment and maintenance of a flood elevation determination docket (FEDD). The Federal...

  4. 44 CFR 66.3 - Establishment of community case file and flood elevation study docket.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... case file and flood elevation study docket. 66.3 Section 66.3 Emergency Management and Assistance... National Flood Insurance Program CONSULTATION WITH LOCAL OFFICIALS § 66.3 Establishment of community case file and flood elevation study docket. (a) A file shall be established for each community at the...

  5. 44 CFR 67.3 - Establishment and maintenance of a flood elevation determination docket (FEDD).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... of a flood elevation determination docket (FEDD). 67.3 Section 67.3 Emergency Management and... MITIGATION National Flood Insurance Program APPEALS FROM PROPOSED FLOOD ELEVATION DETERMINATIONS § 67.3 Establishment and maintenance of a flood elevation determination docket (FEDD). The Federal...

  6. 44 CFR 66.3 - Establishment of community case file and flood elevation study docket.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... case file and flood elevation study docket. 66.3 Section 66.3 Emergency Management and Assistance... National Flood Insurance Program CONSULTATION WITH LOCAL OFFICIALS § 66.3 Establishment of community case file and flood elevation study docket. (a) A file shall be established for each community at the...

  7. 44 CFR 67.3 - Establishment and maintenance of a flood elevation determination docket (FEDD).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... of a flood elevation determination docket (FEDD). 67.3 Section 67.3 Emergency Management and... MITIGATION National Flood Insurance Program APPEALS FROM PROPOSED FLOOD ELEVATION DETERMINATIONS § 67.3 Establishment and maintenance of a flood elevation determination docket (FEDD). The Federal...

  8. 44 CFR 67.3 - Establishment and maintenance of a flood elevation determination docket (FEDD).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... of a flood elevation determination docket (FEDD). 67.3 Section 67.3 Emergency Management and... MITIGATION National Flood Insurance Program APPEALS FROM PROPOSED FLOOD ELEVATION DETERMINATIONS § 67.3 Establishment and maintenance of a flood elevation determination docket (FEDD). The Federal...

  9. 44 CFR 66.3 - Establishment of community case file and flood elevation study docket.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... case file and flood elevation study docket. 66.3 Section 66.3 Emergency Management and Assistance... National Flood Insurance Program CONSULTATION WITH LOCAL OFFICIALS § 66.3 Establishment of community case file and flood elevation study docket. (a) A file shall be established for each community at the...

  10. 76 FR 57050 - Approaches to Reducing Sodium Consumption; Establishment of Dockets; Request for Comments, Data...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ... Approaches to Reducing Sodium Consumption; Establishment of Dockets; Request for Comments, Data, and... dockets to obtain comments, data, and evidence relevant to the dietary intake of sodium as well as current and emerging approaches designed to promote sodium reduction. FDA and FSIS are particularly...

  11. 33 CFR 148.207 - How and where may I view docketed documents?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: GENERAL Processing Applications General § 148.207 How... Docket Management System Web site at http://www.dot.dms.gov. The projects are also listed by name and the assigned docket number at the G-PSO-5 Web site: http://www.uscg.mil/hq/g-m/mso/mso5.htm....

  12. 33 CFR 148.207 - How and where may I view docketed documents?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: GENERAL Processing Applications General § 148.207 How... Docket Web site at www.regulations.gov. The projects are also listed by name and the assigned docket number at the CG-OES-4 Web site: http://www.uscg.mil/hq/cg5/cg522/cg5225....

  13. 33 CFR 148.207 - How and where may I view docketed documents?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: GENERAL Processing Applications General § 148.207 How... Docket Management System Web site at http://www.dot.dms.gov. The projects are also listed by name and the assigned docket number at the G-PSO-5 Web site: http://www.uscg.mil/hq/g-m/mso/mso5.htm....

  14. 33 CFR 148.207 - How and where may I view docketed documents?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: GENERAL Processing Applications General § 148.207 How... Docket Management System Web site at http://www.dot.dms.gov. The projects are also listed by name and the assigned docket number at the G-PSO-5 Web site: http://www.uscg.mil/hq/g-m/mso/mso5.htm....

  15. 59 FR- Realty Action; Ada and Owyhee, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    1994-05-03

    ...-332A-02; IDI-29516] Realty Action; Ada and Owyhee, ID AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Realty Action--IDI-29516; Exchange of public and private lands in Ada and Owyhee.... Containing 640 acres, more or less, in Owyhee County. The purpose of this exchange is to dispose of...

  16. 75 FR 57769 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ... existing and projected publicly owned wastewater treatment works (POTWs) and other water pollution control... other water pollution control facilities, existing and projected, in the United States. The State... to OW-Docket@epa.gov , or by mail to: EPA Docket Center, Environmental Protection Agency,...

  17. (Docket A-93-02) Category II-C: Correspondence Sent to Persons Outside the Agency

    EPA Pesticide Factsheets

    This Index lists correspondence sent to individuals outside EPA that is related to the decision to certify that DOE had met the compliance criteria established by EPA in 40 CFR Part 194 and the disposal regulations set by EPA in 40 CFR Part 191.

  18. 77 FR 66609 - Twenty-Fifth Update of the Federal Agency Hazardous Waste Compliance Docket

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-06

    .... CERCLA Section 103(a) requires the owner or operator of a vessel or onshore or offshore facility to............ Aurora CO 80011 Army 3016 6 Buckley ANG Former Warehouse 660 S Aspen Dr. Aurora CO 80011 Defense 103c 7..., 103C......... 6 Airport. Fort Dix Tacony Warehouse....... 5100 Princeton Ave. Philadelphia..........

  19. 75 FR 62810 - Twenty-Fourth Update of the Federal Agency Hazardous Waste Compliance Docket

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-13

    .... CERCLA Section 103(a) requires the owner or operator of a vessel or onshore or offshore facility to..... Tennessee Gas Pipeline Turkey Run (Station Wyalusing PA 18853 3010 2 319). Hutto-Green Warehouse...

  20. 78 FR 16668 - Twenty-Fifth Update of the Federal Agency Hazardous Waste Compliance Docket

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-18

    ... 98929 Agriculture..... Other 19A City Mill. Campground S 8 mi on NFR 1800 & 1808, 2 mi S of Granite Lake Prospect, 30 mi W of Cy, T15N R12E Sec PB40 SE & Sec PB41 NE. USDA FS Wenatchee NF: Granite From Bumping... 20A Center--Forest Glenn Annex. c--Granite-Control 2845 Hernwood Woodstock MD 21163 Army 103C, 3016...

  1. (Docket A-93-02) Category II-D: Correspondence From Persons Outside the Agency

    EPA Pesticide Factsheets

    This Index lists correspondence from individuals outside EPA that is related to the decision to certify that DOE had met the compliance criteria established by EPA in 40 CFR Part 194 and the disposal regulations set by EPA in 40 CFR Part 191.

  2. 76 FR 9266 - Proposed Amendment of Class D and Class E Airspace; Idaho Falls, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-17

    ... Falls, ID AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking (NPRM). SUMMARY: This action proposes to amend the Class D and Class E airspace areas at Idaho Falls, ID, by changing the name of the airport to Idaho Falls Regional Airport, and adjusting the...

  3. 76 FR 25537 - Amendment of Class E Airspace; McCall, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-05

    ... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; McCall, ID AGENCY: Federal... Airspace at McCall Municipal Airport, McCall, ID. Decommissioning of the McCall Non- Directional Beacon (NDB) at McCall Municipal Airport has made this action necessary for the safety and management...

  4. 76 FR 8324 - Proposed Amendment of Class E Airspace; McCall, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-14

    ... Federal Aviation Administration 14 CFR Part 71 Proposed Amendment of Class E Airspace; McCall, ID AGENCY... action proposes to amend Class E airspace at McCall Municipal Airport, McCall, ID. Decommissioning of the McCall Non- Directional Beacon (NDB) at McCall Municipal Airport has made this action necessary...

  5. 15 CFR 904.201 - Hearing requests and case docketing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... respondent wishes a hearing on a NOVA, NOPS or NIDP, the request must be dated and in writing, and must be... either attach a copy of the NOVA, NOPS or NIDP or refer to the relevant NOAA case number. Agency...

  6. 15 CFR 904.201 - Hearing requests and case docketing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... respondent wishes a hearing on a NOVA, NOPS or NIDP, the request must be dated and in writing, and must be... either attach a copy of the NOVA, NOPS or NIDP or refer to the relevant NOAA case number. Agency...

  7. 15 CFR 904.201 - Hearing requests and case docketing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... respondent wishes a hearing on a NOVA, NOPS or NIDP, the request must be dated and in writing, and must be... either attach a copy of the NOVA, NOPS or NIDP or refer to the relevant NOAA case number. Agency...

  8. 15 CFR 904.201 - Hearing requests and case docketing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... respondent wishes a hearing on a NOVA, NOPS or NIDP, the request must be dated and in writing, and must be... either attach a copy of the NOVA, NOPS or NIDP or refer to the relevant NOAA case number. Agency...

  9. 15 CFR 904.201 - Hearing requests and case docketing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... respondent wishes a hearing on a NOVA, NOPS or NIDP, the request must be dated and in writing, and must be... either attach a copy of the NOVA, NOPS or NIDP or refer to the relevant NOAA case number. Agency...

  10. Threshold extended ID3 algorithm

    NASA Astrophysics Data System (ADS)

    Kumar, A. B. Rajesh; Ramesh, C. Phani; Madhusudhan, E.; Padmavathamma, M.

    2012-04-01

    Information exchange over insecure networks needs to provide authentication and confidentiality to the database in significant problem in datamining. In this paper we propose a novel authenticated multiparty ID3 Algorithm used to construct multiparty secret sharing decision tree for implementation in medical transactions.

  11. 75 FR 63462 - Smart Grid Interoperability Standards; Notice of Docket Designation for Smart Grid...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... Energy Regulatory Commission Smart Grid Interoperability Standards; Notice of Docket Designation for Smart Grid Interoperability Standards October 7, 2010. 1. The Energy Independence and Security Act of... interoperability of smart grid devices and systems, including protocols and model standards for...

  12. 48 CFR 6104.404 - Reply to agency response [Rule 404].

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., GENERAL SERVICES ADMINISTRATION TRAVEL AND RELOCATION EXPENSES CASES 6104.404 Reply to agency response . A... 30 calendar days from the time the claim is docketed by the Board (or 60 calendar days...

  13. 77 FR 1484 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-10

    ... Request; State Water Quality Program Management Resource Analysis (New) AGENCY: Environmental Protection... docket, go to www.regulations.gov . Title: State Water Quality Program Management Resource Analysis (New..., in partnership with states, is conducting the State Water Quality Program Management...

  14. 78 FR 6096 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    ... Request; NESHAP for Miscellaneous Organic Chemical Manufacturing (Renewal) AGENCY: Environmental... the electronic docket, go to www.regulations.gov . Title: NESHAP for Miscellaneous Organic Chemical... disclose the information. Respondents/Affected Entities: Miscellaneous organic chemical...

  15. 76 FR 24924 - Agency Information Collection Activities: Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-03

    ... agency adheres to public laws, the work proceeds on schedule, and that disputes between the Government... should reference Docket No. NRC- 2011-0065. You may submit your comments by any of the following...

  16. 78 FR 41066 - Agency Information Collection Activities; Proposed Collection; Comment Request; Testing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-09

    ... HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities; Proposed...: Food and Drug Administration, HHS. ] ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is... Division of Dockets Management (HFA- 305), Food and Drug Administration, 5630 Fishers Lane, Rm....

  17. 77 FR 77074 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-31

    ... Request; NSPS for Industrial/Commercial/ Institutional Steam Generating Units (Renewal) AGENCY... information about the electronic docket, go to www.regulations.gov . Title: NSPS for Industrial/Commercial... purposes of collecting, validating, and verifying information, processing and maintaining information,...

  18. 76 FR 11775 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-03

    ... Request; Underground Storage Tanks: Technical and Financial Requirements and State Program Approval... Agency, Underground Storage Tank (UST) Docket, Mail Code 28221T, 1200 Pennsylvania Ave., NW., Washington... FURTHER INFORMATION CONTACT: Hal White, Office of Underground Storage Tanks, Mail Code...

  19. 40 CFR 154.15 - Docket for the Special Review.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... information claimed to be confidential business information) referred to by the Agency in those notices as... (other than information claimed to be confidential business information) responding to any notice furnished under § 154.21 or § 154.23 or submitted at any time during the Special Review process by...

  20. Privacy Impact Assessment for the Federal Docket Management System

    EPA Pesticide Factsheets

    This system collects the name and contact information for users who submit comments, in addition to agency users. Learn how the data is collected, how it will be used, access to the data, the purpose of data collection, and record retention policies.

  1. Id-1 and Id-2 are markers for metastasis and prognosis in oesophageal squamous cell carcinoma.

    PubMed

    Yuen, H-F; Chan, Y-P; Chan, K-K; Chu, Y-Y; Wong, M L-Y; Law, S Y-K; Srivastava, G; Wong, Y-C; Wang, X; Chan, K-W

    2007-11-19

    Id protein family consists of four members namely Id-1 to Id-4. Different from other basic helix-loop-helix transcription factors, they lack the DNA binding domain. Id proteins have been shown to be dysregulated in many different cancer types and their prognostic value has also been demonstrated. Recently, Id-1 has been shown to be upregulated in oesophageal squamous cell carcinoma (ESCC). However, the prognostic implications of Id proteins in ESCC have not been reported. We examined the expression of the Id proteins in ESCC cell lines and clinical ESCC specimens and found that Id protein expressions were dysregulated in both the ESCC cell lines and specimens. By correlating the expression levels of Id proteins and the clinicopathological data of our patient cohort, we found that M1 stage tumours had significantly higher nuclear Id-1 expression (P=0.012) while high nuclear Id-1 expression could predict development of distant metastasis within 1 year of oesophagectomy (P=0.005). In addition, high levels of Id-2 expression in both cytoplasmic and nuclear regions predicted longer patient survival (P=0.041). Multivariate analysis showed that high-level expression of Id-2 in both cytoplasmic and nuclear regions and lower level of nuclear Id-1 expression were independent favourable predictors of survival in our ESCC patients. Our results suggest that Id-1 may promote distant metastasis in ESCC, and both Id-1 and Id-2 may be used for prognostication for ESCC patients.

  2. Designing the IDS business portfolio.

    PubMed

    Etchen, L L; Bouton, J L

    2000-01-01

    The business-value model is a strategic and business decision-making tool that can help integrated delivery systems (IDSs) evaluate the relative value that their individual businesses contribute to their overall systems. To use the model, IDSs first need to identify their individual business lines using criteria such as scope, size, marketability, operations, and competition. Businesses then are categorized as core, continuum, cash, or complementary based on four criteria: system purpose, size as reflected by annual revenue, competitive position, and level of profitability. Standards for these criteria should be set by the IDS in accordance with its market circumstances.

  3. 77 FR 6827 - Agency Information Collection Activities: Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-09

    ... (d) obtain consent to export Category 1 quantities of materials listed in Appendix P to 10 CFR part... export Category 1 quantities of byproduct material listed in Appendix P to 10 CFR part 110. The NRC Form... should reference Docket ID NRC-2011-0280. You may submit your comments by any of the following...

  4. 77 FR 31006 - Agency Information Collection Activities; Proposed Collection; Comment Request; Valuing Improved...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-24

    .... Make sure to submit your comments by the deadline identified under DATES. 7. To ensure proper receipt by EPA, be sure to identify the docket ID number assigned to this action in the subject line on the...; search data sources; complete and review the collection of information; and transmit or...

  5. 78 FR 36754 - Agency Information Collection Activities; Submission to the Office of Management and Budget for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-19

    ...: Department of Education (ED), Office of the Secretary/Office of the Deputy Secretary (OS) ACTION: Notice. SUMMARY: In accordance with the Paperwork Reduction Act of 1995 (44 U.S.C. chapter 3501 et seq.), ED is... by selecting Docket ID number ED-2013-ICCD- 0042 or via postal mail, commercial delivery, or...

  6. 78 FR 30900 - Agency Information Collection Activities; Submission to the Office of Management and Budget for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-23

    ...), Department of Education (ED). ACTION: Notice. SUMMARY: In accordance with the Paperwork Reduction Act of 1995 (44 U.S.C. chapter 3501 et seq.), ED is proposing an extension of an existing information collection... Portal at http://www.regulations.gov by selecting Docket ID number ED-2013-ICCD- 0067 or via postal...

  7. 78 FR 6082 - Agency Information Collection Activities; Submission to the Office of Management and Budget for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    ... Student Aid (FSA), Department of Education (ED). ACTION: Notice. SUMMARY: In accordance with the Paperwork Reduction Act of 1995 (44 U.S.C. chapter 3501 et seq.), ED is proposing an extension of an existing... through the Federal eRulemaking Portal at http://www.regulations.gov by selecting Docket ID number...

  8. 78 FR 49486 - Agency Information Collection Activities; Submission to the Office of Management and Budget for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-14

    ... Postsecondary Education (OPE), Department of Education (ED). ACTION: Notice. SUMMARY: In accordance with the Paperwork Reduction Act of 1995 (44 U.S.C. chapter 3501 et seq.), ED is proposing a revision of an existing... through the Federal eRulemaking Portal at http://www.regulations.gov by selecting Docket ID number...

  9. 78 FR 24394 - Agency Information Collection Activities; Submission to the Office of Management and Budget for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-25

    ... Education (ED), Federal Student Aid (FSA). ACTION: Notice. SUMMARY: In accordance with the Paperwork Reduction Act of 1995 (44 U.S.C. chapter 3501 et seq.), ED is proposing an extension of an existing... Federal eRulemaking Portal at http://www.regulations.gov by selecting Docket ID number ED-2013-ICCD-...

  10. 77 FR 47631 - Agency Information Collection Activities: Request for Comments on Twenty-Four Proposed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-09

    ...: NSPS for Synthetic Fiber Production Facilities (40 CFR Part 60, Subpart HHH). ICR Numbers: EPA ICR..., 2012. (9) NSPS for Synthetic Fiber Production Facilities (40 CFR Part 60, Subpart HHH); Learia Williams... Part 60, Subpart HHH); Docket ID Number EPA-HQ-OECA-2012-0528; EPA ICR Number 1156.12; OMB...

  11. 76 FR 20662 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    ... by Docket ID No. EPA-R10- OAR-2010-0858, to (1) EPA online using http://www.regulations.gov (our...-R10-OAR-2010-0858, which is available for online viewing at http://www.regulations.gov , or in person... at http://www.regulations.gov , to submit or view public comments, access the index listing of...

  12. 78 FR 46675 - Agency Information Collection Activities: Request for Comments for a New Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-01

    ... comments identified by DOT Docket ID 2013- 0047 by any of the following methods: Web site: For access to... Federal holidays. SUPPLEMENTARY INFORMATION: Title: Fixed Residential Moving Cost Schedule. OMB Control... payments for actual and reasonable moving and related expenses. The fixed residential moving cost...

  13. 75 FR 38521 - Registration Review; Biopesticide Dockets Opened for Review and Comment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... registration review dockets for the pesticides listed in the table in Unit III.A. of this notice. With this... EPA's periodic review of pesticide registrations to ensure that each pesticide continues to satisfy the statutory standard for registration, that is, the pesticide can perform its intended...

  14. 7 CFR 1944.410 - Processing preapplications, applications, and completing grant dockets.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Technical Assistance Grants § 1944.410 Processing preapplications, applications, and completing grant dockets. (a) Form SF-424, “Application for Federal Assistance.” Form SF-424 in an original and one copy...-help assistance. Evidence should be provided that the communities support the activity and that...

  15. 76 FR 18750 - Ocean Renewable Power Company, LLC; Notice of Change in Docket Number

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Ocean Renewable Power Company, LLC; Notice of Change in Docket Number On July 24, 2009, Ocean Renewable Power Company, LLC (ORPC) filed a draft hydrokinetic pilot...

  16. 19 CFR 351.103 - Central Records Unit and Administrative Protective Order and Dockets Unit.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    .... and 5 p.m. on business days. Among other things, the Central Records Unit is responsible for... the APO/Dockets Unit are between 8:30 a.m. and 5 p.m. on business days. Among other things, the APO... 19 Customs Duties 3 2011-04-01 2011-04-01 false Central Records Unit and Administrative...

  17. 15 CFR 400.31 - General application provisions and pre-docketing review.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 2 2014-01-01 2014-01-01 false General application provisions and pre-docketing review. 400.31 Section 400.31 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) FOREIGN-TRADE ZONES BOARD, DEPARTMENT OF COMMERCE REGULATIONS OF THE...

  18. 76 FR 77994 - Brian Hamilton v. El Paso Natural Gas, El Paso Western Pipelines; Notice Announcing Docket Number...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Brian Hamilton v. El Paso Natural Gas, El Paso Western Pipelines; Notice Announcing Docket Number Change On December 2, 2011, the Commission issued a notice in docket number...

  19. 14 CFR 11.35 - Does FAA include sensitive security information and proprietary information in the Federal Docket...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... information and proprietary information in the Federal Docket Management System (FDMS)? 11.35 Section 11.35... RULEMAKING PROCEDURES Rulemaking Procedures General § 11.35 Does FAA include sensitive security information and proprietary information in the Federal Docket Management System (FDMS)? (a) Sensitive...

  20. 14 CFR 11.35 - Does FAA include sensitive security information and proprietary information in the Federal Docket...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... information and proprietary information in the Federal Docket Management System (FDMS)? 11.35 Section 11.35... RULEMAKING PROCEDURES Rulemaking Procedures General § 11.35 Does FAA include sensitive security information and proprietary information in the Federal Docket Management System (FDMS)? (a) Sensitive...

  1. 14 CFR 11.35 - Does FAA include sensitive security information and proprietary information in the Federal Docket...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... information and proprietary information in the Federal Docket Management System (FDMS)? 11.35 Section 11.35... RULEMAKING PROCEDURES Rulemaking Procedures General § 11.35 Does FAA include sensitive security information and proprietary information in the Federal Docket Management System (FDMS)? (a) Sensitive...

  2. 14 CFR 11.35 - Does FAA include sensitive security information and proprietary information in the Federal Docket...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... information and proprietary information in the Federal Docket Management System (FDMS)? 11.35 Section 11.35... RULEMAKING PROCEDURES Rulemaking Procedures General § 11.35 Does FAA include sensitive security information and proprietary information in the Federal Docket Management System (FDMS)? (a) Sensitive...

  3. 49 CFR 837.3 - Published reports, material contained in the public accident investigation dockets, and accident...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... public accident investigation dockets, and accident database data. 837.3 Section 837.3 Transportation... OF RECORDS IN LEGAL PROCEEDINGS § 837.3 Published reports, material contained in the public accident investigation dockets, and accident database data. (a) Demands for material contained in the NTSB's...

  4. 49 CFR 837.3 - Published reports, material contained in the public accident investigation dockets, and accident...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... public accident investigation dockets, and accident database data. 837.3 Section 837.3 Transportation... OF RECORDS IN LEGAL PROCEEDINGS § 837.3 Published reports, material contained in the public accident investigation dockets, and accident database data. (a) Demands for material contained in the NTSB's...

  5. 49 CFR 837.3 - Published reports, material contained in the public accident investigation dockets, and accident...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... public accident investigation dockets, and accident database data. 837.3 Section 837.3 Transportation... OF RECORDS IN LEGAL PROCEEDINGS § 837.3 Published reports, material contained in the public accident investigation dockets, and accident database data. (a) Demands for material contained in the NTSB's...

  6. 49 CFR 837.3 - Published reports, material contained in the public accident investigation dockets, and accident...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... public accident investigation dockets, and accident database data. 837.3 Section 837.3 Transportation... OF RECORDS IN LEGAL PROCEEDINGS § 837.3 Published reports, material contained in the public accident investigation dockets, and accident database data. (a) Demands for material contained in the NTSB's...

  7. 49 CFR 837.3 - Published reports, material contained in the public accident investigation dockets, and accident...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... public accident investigation dockets, and accident database data. 837.3 Section 837.3 Transportation... OF RECORDS IN LEGAL PROCEEDINGS § 837.3 Published reports, material contained in the public accident investigation dockets, and accident database data. (a) Demands for material contained in the NTSB's...

  8. 14 CFR 406.113 - Filing documents with the Docket Management System (DMS) and sending documents to the...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Litigation. 406.113 Section 406.113 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION... Rules of Practice in FAA Space Transportation Adjudications § 406.113 Filing documents with the Docket... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Filing documents with the Docket...

  9. 14 CFR 406.113 - Filing documents with the Docket Management System (DMS) and sending documents to the...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Litigation. 406.113 Section 406.113 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION... Rules of Practice in FAA Space Transportation Adjudications § 406.113 Filing documents with the Docket... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Filing documents with the Docket...

  10. 14 CFR 406.113 - Filing documents with the Docket Management System (DMS) and sending documents to the...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Litigation. 406.113 Section 406.113 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION... Rules of Practice in FAA Space Transportation Adjudications § 406.113 Filing documents with the Docket... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Filing documents with the Docket...

  11. 14 CFR 11.35 - Does FAA include sensitive security information and proprietary information in the Federal Docket...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... information and proprietary information in the Federal Docket Management System (FDMS)? 11.35 Section 11.35... RULEMAKING PROCEDURES Rulemaking Procedures General § 11.35 Does FAA include sensitive security information and proprietary information in the Federal Docket Management System (FDMS)? (a) Sensitive...

  12. 78 FR 73897 - SHINE Medical Technologies, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-09

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION SHINE Medical Technologies, Inc. AGENCY: Nuclear Regulatory Commission. ACTION: License... Technologies, Inc. (SHINE) is acceptable for docketing. ADDRESSES: Please refer to Docket ID NRC-2013-0053...

  13. R&D100: IC ID

    SciTech Connect

    Hamlet, Jason; Pierson, Lyndon; Bauer, Todd

    2015-11-19

    Supply chain security to detect, deter, and prevent the counterfeiting of networked and stand-alone integrated circuits (ICs) is critical to cyber security. Sandia National Laboratory researchers have developed IC ID to leverage Physically Unclonable Functions (PUFs) and strong cryptographic authentication to create a unique fingerprint for each integrated circuit. IC ID assures the authenticity of ICs to prevent tampering or malicious substitution.

  14. R&D100: IC ID

    ScienceCinema

    Hamlet, Jason; Pierson, Lyndon; Bauer, Todd

    2016-07-12

    Supply chain security to detect, deter, and prevent the counterfeiting of networked and stand-alone integrated circuits (ICs) is critical to cyber security. Sandia National Laboratory researchers have developed IC ID to leverage Physically Unclonable Functions (PUFs) and strong cryptographic authentication to create a unique fingerprint for each integrated circuit. IC ID assures the authenticity of ICs to prevent tampering or malicious substitution.

  15. 77 FR 54617 - Agency Information Collection Activities: Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... controls at a nuclear reactor facility. This information is used to determine that each applicant or... Doc No: 2012-21832] NUCLEAR REGULATORY COMMISSION [Docket No. NRC-2012-0184] Agency Information Collection Activities: Proposed Collection; Comment Request AGENCY: Nuclear Regulatory Commission....

  16. 77 FR 22778 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-17

    ... Request; NESHAP for Coke Oven Batteries AGENCY: Environmental Protection Agency (EPA). ACTION: Notice... ] information about the electronic docket, go to www.regulations.gov . Title: NESHAP for Coke Oven Batteries.... Respondents/Affected Entities: Owners or operators of coke oven batteries. Estimated Number of Respondents:...

  17. 78 FR 6098 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    ... Request; NSPS for Coal Preparation and Processing Plants (Renewal) AGENCY: Environmental Protection Agency... docket, go to www.regulations.gov . Title: NSPS for Coal Preparation and Processing Plants (Renewal). ICR.... Respondents/Affected Entities: Coal preparation and processing plants. Estimated Number of Respondents:...

  18. 76 FR 19768 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-08

    ... Request; NESHAP for Beryllium Rocket Motor Fuel Firing (Renewal) AGENCY: Environmental Protection Agency... electronic docket, go to http://www.regulations.gov . Title: NESHAP for Beryllium Rocket Motor Fuel Firing... disclose the information. Respondents/Affected Entities: Owners or operators of beryllium rocket motor...

  19. 76 FR 44581 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-26

    ... Request; EPA's Natural Gas STAR Program (Renewal) AGENCY: Environmental Protection Agency (EPA). ACTION... docket, go to http://www.regulations.gov . Title: EPA's Natural Gas STAR Program. ICR Numbers: EPA ICR No...: Natural Gas STAR is an EPA-sponsored, voluntary program that encourages oil and natural gas companies...

  20. 76 FR 11777 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-03

    ... Request; EPA's ENERGY STAR Product Labeling (Renewal) AGENCY: Environmental Protection Agency (EPA... docket, go to http://www.regulations.gov . Title: EPA's ENERGY STAR Product Labeling (Renewal) ICR... 40 CFR part 9. Abstract: ENERGY STAR is a voluntary program developed in collaboration with...

  1. 76 FR 32981 - Agency Information Collection Activities: Proposed Collection; Comment Request, Write Your Own...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-07

    ...; Comment Request, Write Your Own (WYO) Program AGENCY: Federal Emergency Management Agency, DHS. ACTION... instructions for submitting comments. (2) Mail. Submit written comments to Docket Manager, Office of Chief... address: FEMA-Information-Collections-Management@dhs.gov . SUPPLEMENTARY INFORMATION: Under the Write...

  2. 75 FR 1054 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-08

    ... [Federal Register Volume 75, Number 5 (Friday, January 8, 2010)] [Notices] [Pages 1054-1055] [FR Doc No: 2010-151] ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OECA-2009-0418; FRL-9101-3] Agency... and Compliance Docket and Information [[Page 1055

  3. 76 FR 14967 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-18

    ... Request; NESHAP for Primary Aluminum Reduction Plants (Renewal) AGENCY: Environmental Protection Agency... electronic docket, go to http://www.regulations.gov . Title: NESHAP for Primary Aluminum Reduction Plants.../Affected Entities: Owners or operators of primary aluminum reduction plants. Estimated Number...

  4. 76 FR 41264 - Agency Information Collection Activities; Proposed Collection; Comment Request; Appeals of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-13

    ... HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities; Proposed... Veterinary Medicine AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug... information to the Division of Dockets Management (HFA-305), Food and Drug Administration, 5630 Fishers...

  5. 77 FR 24488 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-24

    ... Request; Landfill Methane Outreach Program (Renewal) AGENCY: Environmental Protection Agency (EPA). ACTION... information about the electronic docket, go to www.regulations.gov . Title: Landfill Methane Outreach Program... consolidated in 40 CFR part 9. Abstract: The Landfill Methane Outreach Program (LMOP), created by EPA as...

  6. 75 FR 8694 - Agency Information Collection Activities; Proposed Collection; Comment Request; Animal Sectors...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... AGENCY Agency Information Collection Activities; Proposed Collection; Comment Request; Animal Sectors..., and be free of any defects or viruses. For additional information about EPA's public docket, visit the... this action are concentrated animal feeding operations (CAFOs) as specified in section 502(14) of...

  7. 76 FR 63667 - Agency Information Collection Activities: Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... Doc No: 2011-26462] NUCLEAR REGULATORY COMMISSION [Docket No. NRC-2011-0227] Agency Information Collection Activities: Proposed Collection; Comment Request AGENCY: Nuclear Regulatory Commission. ACTION... Budget (OMB) and solicitation of public comment. SUMMARY: The U.S. Nuclear Regulatory Commission...

  8. 77 FR 42303 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-18

    ... Request; NSPS for Petroleum Dry Cleaners (Renewal) AGENCY: Environmental Protection Agency (EPA). ACTION... information about the electronic docket, go to www.regulations.gov . Title: NSPS for Petroleum Dry Cleaners... Performance Standards (NSPS) for the Petroleum Dry Cleaners (40 CFR part 60, subpart JJJ) were proposed...

  9. To ID or not to ID? Changes in classification rates of intellectual disability using DSM-5.

    PubMed

    Papazoglou, Aimilia; Jacobson, Lisa A; McCabe, Marie; Kaufmann, Walter; Zabel, T Andrew

    2014-06-01

    The Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition (DSM-5) diagnostic criteria for intellectual disability (ID) include a change to the definition of adaptive impairment. New criteria require impairment in one adaptive domain rather than two or more skill areas. The authors examined the diagnostic implications of using a popular adaptive skill inventory, the Adaptive Behavior Assessment System-Second Edition, with 884 clinically referred children (ages 6-16). One hundred sixty-six children met DSM-IV-TR criteria for ID; significantly fewer (n  =  151, p  =  .001) met ID criteria under DSM-5 (9% decrease). Implementation of DSM-5 criteria for ID may substantively change the rate of ID diagnosis. These findings highlight the need for a combination of psychometric assessment and clinical judgment when implementing the adaptive deficits component of the DSM-5 criteria for ID diagnosis.

  10. 77 FR 56608 - Designation for the Pocatello, ID; Evansville, IN; and Salt Lake City, UT Areas

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ... Designation for the Pocatello, ID; Evansville, IN; and Salt Lake City, UT Areas AGENCY: Grain Inspection....... 10/1/2012 9/30/2015 Ohio Valley Evansville, IN (812) 423-9010... 10/1/2012 9/30/2015 Utah Salt...

  11. 75 FR 45661 - Notice of Permanent Closure on Public Lands in Ada County, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-03

    ... Bureau of Land Management Notice of Permanent Closure on Public Lands in Ada County, ID AGENCY: Bureau of Land Management, Interior. ACTION: Notice of permanent closure. SUMMARY: On April 12, 2010, Higby Cave and all public lands within 1,000 feet of the entrance were permanently closed to vehicle access...

  12. 78 FR 61442 - Idaho Disaster #ID-00027 Declaration of Economic Injury

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-03

    ... ADMINISTRATION Idaho Disaster ID-00027 Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the... the Administrator's EIDL declaration, applications for economic injury disaster loans may be filed...

  13. 75 FR 57053 - Camas National Wildlife Refuge, Jefferson County, ID; Comprehensive Conservation Plan and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-17

    ... Conservation Plan and Environmental Assessment AGENCY: Fish and Wildlife Service, Interior. ACTION: Notice of... prepare a comprehensive conservation plan (CCP) for Camas National Wildlife Refuge (refuge) in Hamer, ID... Refuge System, consistent with sound principles of fish and wildlife management, conservation,...

  14. 81 FR 23746 - Temporary Road Closure on Public Lands in Owyhee County, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2016-04-22

    ... Bureau of Land Management Temporary Road Closure on Public Lands in Owyhee County, ID AGENCY: Bureau of... 1-mile road segment that crosses public lands located in Owyhee County, Idaho, approximately 5 miles... the Owyhee Field Office, 20 First Avenue West, Marsing, Idaho, 83639. National Environmental...

  15. 61 FR 42052 - Owyhee Resource Area, ID; Resource Management Plan, etc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    1996-08-13

    ... Bureau of Land Management Owyhee Resource Area, ID; Resource Management Plan, etc. AGENCY: Bureau of Land... Management Plan (RMP) and associated draft Environmental Impact Statement (EIS) for the Owyhee Resource Area... be sent to: Owyhee Area Manager, Bureau of Land Management, Boise Field Office, 3948...

  16. 61 FR 11862 - Shooting Closures and Restrictions in Ada, Canyon, Elmore, and Owyhee Counties, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    1996-03-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE INTERIOR Shooting Closures and Restrictions in Ada, Canyon, Elmore, and Owyhee Counties, ID AGENCY: Bureau of Land... Bruneau, Kuna, and Owyhee Management Framework Plans. Violation of this order is punishable by a fine...

  17. 70 FR 9098 - Notice of Realty Action, Sale of Public Land in Owyhee County, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2005-02-24

    ... Bureau of Land Management Notice of Realty Action, Sale of Public Land in Owyhee County, ID AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Realty Action, Sale of Public Land in Owyhee... located in Owyhee County, Idaho is suitable for direct sale to Owyhee County under Sections 203 and 209...

  18. 75 FR 1026 - Lower Orogrande Project, Clearwater National Forest, Clearwater County, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-08

    ... stands for management as mature and old growth forest habitats. Possible Alternatives the Forest Service... Doc No: 2010-109] DEPARTMENT OF AGRICULTURE Forest Service Lower Orogrande Project, Clearwater National Forest, Clearwater County, ID AGENCY: Forest Service, USDA. ACTION: Notice of intent to prepare...

  19. Inhibitor of differentiation 4 (ID4): From development to cancer.

    PubMed

    Patel, Divya; Morton, Derrick J; Carey, Jason; Havrda, Mathew C; Chaudhary, Jaideep

    2015-01-01

    Highly conserved Inhibitors of DNA-Binding (ID1-ID4) genes encode multi-functional proteins whose transcriptional activity is based on dominant negative inhibition of basic helix-loop-helix (bHLH) transcription factors. Initial animal models indicated a degree of compensatory overlap between ID genes such that deletion of multiple ID genes was required to generate easily recognizable phenotypes. More recently, new model systems have revealed alterations in mice harboring deletions in single ID genes suggesting complex gene and tissue specific functions for members of the ID gene family. Because ID genes are highly expressed during development and their function is associated with a primitive, proliferative cellular phenotype there has been significant interest in understanding their potential roles in neoplasia. Indeed, numerous studies indicate an oncogenic function for ID1, ID2 and ID3. In contrast, the inhibitor of differentiation 4 (ID4) presents a paradigm shift in context of well-established role of ID1, ID2 and ID3 in development and cancer. Apart from some degree of functional redundancy such as HLH dependent interactions with bHLH protein E2A, many of the functions of ID4 are distinct from ID1, ID2 and ID3: ID4 proteins a) regulate distinct developmental processes and tissue expression in the adult, b) promote stem cell survival, differentiation and/or timing of differentiation, c) epigenetic inactivation/loss of expression in several advanced stage cancers and d) increased expression in some cancers such as those arising in the breast and ovary. Thus, in spite of sharing the conserved HLH domain, ID4 defies the established model of ID protein function and expression. The underlying molecular mechanism responsible for the unique role of ID4 as compared to other ID proteins still remains largely un-explored. This review will focus on the current understanding of ID4 in context of development and cancer.

  20. Id-1 and Id-2 genes and products as markers of epithelial cancer

    DOEpatents

    Desprez, Pierre-Yves; Campisi, Judith

    2008-09-30

    A method for detection and prognosis of breast cancer and other types of cancer. The method comprises detecting expression, if any, for both an Id-1 and an Id-2 genes, or the ratio thereof, of gene products in samples of breast tissue obtained from a patient. When expressed, Id-1 gene is a prognostic indicator that breast cancer cells are invasive and metastatic, whereas Id-2 gene is a prognostic indicator that breast cancer cells are localized and noninvasive in the breast tissue.

  1. Id-1 and Id-2 genes and products as markers of epithelial cancer

    DOEpatents

    Desprez, Pierre-Yves [El Cerrito, CA; Campisi, Judith [Berkeley, CA

    2011-10-04

    A method for detection and prognosis of breast cancer and other types of cancer. The method comprises detecting expression, if any, for both an Id-1 and an Id-2 genes, or the ratio thereof, of gene products in samples of breast tissue obtained from a patient. When expressed, Id-1 gene is a prognostic indicator that breast cancer cells are invasive and metastatic, whereas Id-2 gene is a prognostic indicator that breast cancer cells are localized and noninvasive in the breast tissue.

  2. Commission decision on the Northern California Power Agency's Application for Certification for Geothermal Project No. 2. Docket 79-AFC-2

    SciTech Connect

    Not Available

    1980-03-01

    The text of the Decision is presented in narrative form. Included are: findings on compliance with statutory site certification requirements, a discussion of the Joint Environmental Study and its significance in terms of the California Environmental Quality and National Environmental Policy Acts, a brief recapitulation of the procedural steps which occurred, and a summary of the evidentiary bases for this Decision. Also presented are topical discussions on the various human and natural environmental areas impacted by the project, as well as the technical, engineering, and other areas of concern affected by the project. These topical discussions summarize the basis for the Commission's ultimte Findings and Conclusions pertaining to each broad cetegory. (MHR)

  3. Suggested References. PACE I.D. Center.

    ERIC Educational Resources Information Center

    Bergson, Rita

    During the course of the PACE I.D. Center Project, 1966-1969, staff members recorded references that they felt contributed to the general knowledge of the prevention of learning and behavior problems. More specifically, those references that implied concern for the child in his total environment were considered most relevant. The references are…

  4. What Is "Real-World" ID Anyway?

    ERIC Educational Resources Information Center

    Hardre, Patricia L.

    2013-01-01

    The term "real-world ID" is commonly heard at professional conferences, but its meaning is assumed rather than defined. Unless we examine the meanings and implications of rhetoric of the field, we risk error in presenting ourselves, and we risk derailing the progress of our profession. This article examines the term "real world" as applied to…

  5. 41 CFR 102-79.90 - What criteria must Executive agencies consider when evaluating antenna siting requests?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... maintenance; (b) Aesthetics; (c) Effects on historic districts, sites, buildings, monuments, structures, or... radiofrequency exposure, ET Docket No. 93-62, entitled “Guidelines for Evaluating the Environmental Effects of... agencies such as the Environmental Protection Agency and the Food and Drug Administration; and (g)...

  6. 76 FR 81955 - Assessment Questionnaire-IP Sector Specific Agency Risk Self Assessment Tool (IP-SSARSAT)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... SECURITY Assessment Questionnaire--IP Sector Specific Agency Risk Self Assessment Tool (IP-SSARSAT) AGENCY... Information Collection Request: 1670-NEW. SUMMARY: The Department of Homeland Security (DHS), National... received must include the words ``Department of Homeland Security'' and the docket ] number for this...

  7. 77 FR 33227 - Assessment Questionnaire-IP Sector Specific Agency Risk Self Assessment Tool (IP-SSARSAT)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-05

    ... SECURITY Assessment Questionnaire--IP Sector Specific Agency Risk Self Assessment Tool (IP-SSARSAT) AGENCY... Information Collection Request, 1670-NEW. SUMMARY: The Department of Homeland Security (DHS), National... words ``Department of Homeland Security'' and the docket number for this action. Comments received...

  8. Id-1, Id-2, and Id-3 co-expression correlates with prognosis in stage I and II lung adenocarcinoma patients treated with surgery and adjuvant chemotherapy.

    PubMed

    Antonângelo, Leila; Tuma, Taila; Fabro, Alexandre; Acencio, Milena; Terra, Ricardo; Parra, Edwin; Vargas, Francisco; Takagaki, Teresa; Capelozzi, Vera

    2016-06-01

    Inhibitors of DNA binding/inhibitors of differentiation (Id) protein family have been shown to be involved in carcinogenesis. However, the roles of Id during lung adenocarcinoma (ADC) progression remain unclear. Eighty-eight ADC samples were evaluated for Id-1,2,3 level and angiogenesis (CD 34 and VEGF microvessel density) by immunohistochemistry and morphometry. The impact of these markers was tested on follow-up until death or recurrence. A significant difference between tumor and normal tissue was found for Id-1,2,3 expression (P < 0.01). In addition, high levels of nuclear Id-1 were associated with higher angiogenesis in the tumor stroma (P < 0.01). Equally significant was the association between patients in T1-stage and low cytoplasmic Id-2, as well as patients in stage-IIb and low Id-3. High cytoplasm Id-3 expression was also directly associated to lymph nodes metastasis (P = 0.05). Patients at stages I to III, with low Id-1 and Id-3 cytoplasm histoscores showed significant long metastasis-free survival time than those with high Id-1 or Id-3 expression (P = 0.04). Furthermore, high MVD-CD34 and MVD-VEGF expression were associated with short recurrence-free survival compared to low MVD-CD34 and MVD-VEGF expressions (P = 0.04). Cox model analyses controlled for age, lymph node metastasis, and adjuvant treatments showed that nuclear Id-1, cytoplasmic Id-3, and MVD-CD34 were significantly associated with survival time. Median score for nuclear Id-1 and cytoplasmic Id-3 divided patients in two groups, being that those with increased Id-1 and Id-3 presented higher risk of death. Ids showed an independent prognostic value in patients with lung ADC, regardless of disease stage. Id-1 and Id-3 should be considered new target candidates in the development of personalized therapy in lung ADC.

  9. Molecular characterization of antibodies bearing Id-460. II. Molecular basis for Id-460 expression

    PubMed Central

    1985-01-01

    Id-460+ immunoglobulins can be induced in vivo by immunization with dinitrophenyl (DNP) or P. pneumotropica and form two nonoverlapping groups of antibodies with respect to antigen binding specificity. In this study, using Id-460+ antibodies of differing antigen binding specificities, we compared on the molecular genetic level the five gene segment combinations (VH, DH, JH, VL, and JL) that encode the variable regions of these idiotype-positive immunoglobulins. The Id-460 determinant appears to be a conformational or combinatorial determinant encoded by VH460 and VK1 crosshybridizing genes. DH, JH, and JK gene segments appear to have no measurable effect upon expression of Id-460. Finally, antigen binding specificity does not appear to simply localize to any particular gene segment but may in part be the result of somatic mutation and/or VDJH junctional sequences, whose length correlates roughly with antigen binding specificity. PMID:3932578

  10. 75 FR 16100 - Antimicrobial Pesticide Registration Review Dockets Opened for Review and Comment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-31

    ... for the pesticides listed in the table in Unit III.A. With this document, EPA is opening the public comment period for these registration reviews. Registration review is EPA's periodic review of pesticide... identification (ID) number for the specific pesticide of interest provided in the table in Unit III.A., by one...

  11. 75 FR 16114 - Registration Review; Biopesticides Dockets Opened for Review and Comment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-31

    ... pesticides listed in the table in Unit III.A. With this document, EPA is opening the public comment period for these registration reviews. Registration review is EPA's periodic review of pesticide... identification (ID) number for the specific pesticide of interest provided in the table in Unit III.A., by one...

  12. 77 FR 12293 - PCBs Bulk Product v. Remediation Waste

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-29

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY PCBs Bulk Product v. Remediation Waste AGENCY: Environmental Protection Agency (EPA). ACTION..., Attention Docket ID No. EPA-HQ-RCRA-2011-0847. Mail: U.S. Environmental Protection Agency; EPA Docket...

  13. Beam transport radiation shielding for branch lines 2-ID-B and 2-ID-C

    SciTech Connect

    Feng, Y.P.; Lai, B.; McNulty, I.; Dejus, R.J.; Randall, K.J.; Yun, W.

    1995-08-01

    The x-ray radiation shielding requirements beyond the first optics enclosure have been considered for the beam transport of the 2-ID-B and 2-ID-C branch lines of Sector 2 (SRI-CAT) of the APS. The first three optical components (mirrors) of the 2-ID-B branch are contained within the shielded first optics enclosure. Calculations indicate that scattering of the primary synchrotron beam by beamline components outside the enclosure, such as apertures and monochromators, or by gas particles in case of vacuum failure is within safe limits for this branch. A standard 2.5-inch-diameter stainless steel pipe with 1/16-inch-thick walls provides adequate shielding to reduce the radiation dose equivalent rate to human tissue to below the maximum permissible limit of 0.25 mrem/hr. The 2-ID-C branch requires, between the first optics enclosure where only two mirrors are used and the housing for the third mirror, additional lead shielding (0.75 mm) and a minimum approach distance of 2.6 cm. A direct beam stop consisting of at least 4.5 mm of lead is also required immediately downstream of the third mirror for 2-ID-C. Finally, to stop the direct beam from escaping the experimental station, a beam stop consisting of at least 4-mm or 2.5-mm steel is required for the 2-ID-B or 2-ID-C branches, respectively. This final requirement can be met by the vacuum chambers used to house the experiments for both branch lines.

  14. 76 FR 35896 - Agency Information Collection Activities; Proposed Collection; Comment Request; Guidance for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ... Pharmaceutical Current Good Manufacturing Practice AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing an opportunity for public comment on the... Doc No: 2011-15141] DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket...

  15. 77 FR 58538 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-21

    ... Request; NESHAP for the Wood Building Products Surface Coating Industry (Renewal) AGENCY: Environmental... docket, go to www.regulations.gov . Title: NESHAP for the Wood Building Products Surface Coating Industry...: Owners or operators of wood building products surface coating facilities. Estimated Number of...

  16. 76 FR 9020 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-16

    ... Consultation Procedures: Foods Derived From New Plant Varieties AGENCY: Food and Drug Administration, HHS...: Foods Derived From New Plant Varieties.'' Also include the FDA docket number found in brackets in the... From New Plant Varieties--(OMB Control Number 0910-NEW) I. Background Since 1992, when FDA issued...

  17. 78 FR 36771 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-19

    ... Request; NSPS for Automobile and Light Duty Truck Surface Coating Operations (Renewal) AGENCY... information about the electronic docket, go to www.regulations.gov . Title: NSPS for Automobile and Light Duty... automobile and light duty truck surface coating operations Estimated Number of Respondents: 60 Frequency...

  18. 77 FR 51027 - Agency Information Collection Activities; Proposed Collection; Comment Request; Communicating...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-23

    ... information to the Division of Dockets Management (HFA- 305), Food and Drug Administration, 5630 Fishers Lane... Information Management, Food and Drug Administration, 1350 Piccard Dr., PI50-400B, Rockville, MD 20850, 301...), Federal Agencies must obtain approval from the Office of Management and Budget (OMB) for each...

  19. 77 FR 44225 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-27

    ... Request; NESHAP for Coke Oven Pushing, Quenching, and Battery Stacks (Renewal) AGENCY: Environmental... docket, go to www.regulations.gov . Title: NESHAP for Coke Oven Pushing Quenching and Battery Stacks...: Owners or operators of coke oven pushing, quenching, and battery stacks. Estimated Number of...

  20. 77 FR 77073 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-31

    ... Request; NSPS for Fossil Fuel Fired Steam Generating Units (Renewal) AGENCY: Environmental Protection... docket, go to www.regulations.gov . Title: NSPS for Fossil Fuel Fired Steam Generating Units(Renewal.... Respondents/Affected Entities: Owners or operators of fossil fuel fired steam generating units....

  1. 76 FR 19767 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-08

    ... Request; NESHAP for Epoxy Resin and Non- Nylon Polyamide Production (Renewal) AGENCY: Environmental... comments the electronic docket, go to http://www.regulations.gov . Title: NESHAP for Epoxy Resin and Non... Standards for Hazardous Air Pollutants (NESHAP) for Epoxy Resin and Non-Nylon Polyamide Production...

  2. 77 FR 20383 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-04

    ... Request; NESHAP for Inorganic Arsenic Emissions From Glass Manufacturing Plants AGENCY: Environmental... information about the electronic docket, go to www.regulations.gov . Title: NESHAP for Inorganic Arsenic... Arsenic Emissions from Glass Manufacturing Plants were proposed on July 20, 1983, and promulgated...

  3. 76 FR 76158 - Agency Information Collection Activities; Proposed Collection; Comment Request; RCRA Expanded...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-06

    ... . FOR FURTHER INFORMATION CONTACT: Michael Pease, (5303P), Environmental Protection Agency, 1200...; email address: pease.michael@epa.gov . SUPPLEMENTARY INFORMATION: How can I access the docket and/or... Pease at (703) 308-0008 or pease.michael@epa.gov . Dated: November 22, 2011. Suzanne Rudzinski,...

  4. 77 FR 65683 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-30

    ... Request; EPA's Design for the Environment (DfE) Partner of the Year Awards Program AGENCY: Environmental... Environment (DfE) Partner of the Year Awards Program; EPA ICR No. 2450.01, OMB No. 2070-NEW. The ICR, which is... electronic docket, go to www.regulations.gov . Title: EPA's Design for the Environment (DfE) Partner of...

  5. 78 FR 76187 - Transportation Infrastructure Financing and Innovation Act (TIFIA) Program; Agency Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-16

    .... OST requests that the Office of Management and Budget (OMB) renew an Information Collection Request... and Regulatory Affairs, Office of Management and Budget, Docket Library, Room 10102, 725 17th Street...: State and local governments, transit agencies, railroad companies, special authorities,...

  6. 75 FR 55324 - Agency Information Collection Activities: Proposed Collection; Comment Request; 2011 Drinking...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-10

    ... at http://www.epa.gov/dockets . FOR FURTHER INFORMATION CONTACT: Robert Barles, Drinking Water Protection Division (Mail Code 4606M), Office of Ground Water and Drinking Water, U.S. EPA, 1200 Pennsylvania... agencies, and state departments of health. Title: 2011 Drinking Water Infrastructure Needs Survey...

  7. 78 FR 18977 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-28

    ... Request; NSPS for Pressure Sensitive Tape and Label Surface Coating Operations (Renewal) AGENCY... further information about the electronic docket, go to www.regulations.gov . Title: NSPS for Pressure... disclose the information. Respondents/Affected Entities: Owners or operators of pressure sensitive tape...

  8. 78 FR 3413 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-16

    ... Request; NSPS for Surface Coating of Plastic Parts for Business Machines (Renewal) AGENCY: Environmental... the electronic docket, go to www.regulations.gov . Title: NSPS for Surface Coating of Plastic Parts... surface coatings to plastic parts for use in the manufacture of business machines. Estimated Number...

  9. 76 FR 33274 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... Request; NESHAP for Area Sources: Electric Arc Furnace Steelmaking Facilities (Renewal) AGENCY... electronic docket, go to http://www.regulations.gov . Title: NESHAP for Area Sources: Electric Arc Furnace.../Affected Entities: Owners or operators of electric arc furnace steelmaking facilities. Estimated Number...

  10. 78 FR 6097 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    ... Request; NESHAP for Paints and Allied Products Manufacturing Area Source Category (Renewal) AGENCY... information about the electronic docket, go to www.regulations.gov . Title: NESHAP for Paints and Allied... affected by this action are the owners or operators of paints and allied products manufacturing...

  11. 48 CFR 6104.404 - Reply to agency response [Rule 404].

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... claimant may file a reply to the agency response within 30 calendar days after receiving the response (or within 60 calendar days after receiving the response, if the claimant is located outside the 50 states... 30 calendar days from the time the claim is docketed by the Board (or 60 calendar days...

  12. 77 FR 64511 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-22

    ... Request; NESHAP for Aluminum, Copper and Other Non-Ferrous Metals Foundries (Renewal) AGENCY... information about the electronic docket, go to www.regulations.gov . Title: NESHAP for Aluminum, Copper and... disclose the information. Respondents/Affected Entities: Aluminum, copper and other non- ferrous...

  13. 75 FR 4066 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-26

    ... Request; Chesapeake Registry; EPA ICR No. 2365.02, OMB Control No. 2003-0001 AGENCY: Environmental... docket, go to http://www.regulations.gov . Title: Chesapeake Registry. ICR numbers: EPA ICR No. 2365.02... titled Chesapeake Registry. Through this reporting system, participating organizations provide data...

  14. 77 FR 29663 - Agency Information Collection Activities: Proposed Collection; Comment Request; User Fee Cover...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    ... Doc No: 2012-12038] DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No... Fee Cover Sheet; Form FDA 3397 AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing an opportunity for public comment on the...

  15. 76 FR 80361 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ... Streamlining Rule. EPA's Office of Wastewater Management (OWM) in the Office of Water (OW) is responsible for... Information Collection Request (ICR) has been forwarded to the Office of Management and Budget (OMB) for...), or by mail to: Water Docket, Environmental Protection Agency, Mailcode: 28221T, 1200 Pennsylvania...

  16. 76 FR 38148 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ... Request; Implementation of the Oil Pollution Act Facility Response Plan Requirements (Renewal) AGENCY... docket, go to www.regulations.gov . Title: Implementation of the Oil Pollution Act Facility Response Plan... amended by the Oil Pollution Act of 1990 and in regulation codified at 40 CFR 112.20 and 112.21,...

  17. 75 FR 52003 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-24

    ... Control System Performance Warranty Regulations and Voluntary Aftermarket Part Certification Program... docket, go to http://www.regulations.gov . Title: Emission Control System Performance Warranty... AGENCY [EPA-HQ-OAR-2009-0983; FRL-9192-4; EPA ICR No. 0116.09; OMB Control No. 2060-0060]...

  18. 76 FR 4117 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-24

    ... Office of Management and Budget Review; Comment Request; Prescription Drug Advertisements AGENCY: Food... ``Prescription Drug Advertisements''. Also include the FDA docket number found in brackets in the heading of this... Advertisements--(OMB Control Number 0910)--New Section 502(n) of the Federal Food, Drug, and Cosmetic Act (the...

  19. 78 FR 42521 - Agency Information Collection Activities: Announcement of Board Approval Under Delegated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-16

    ... From the Federal Register Online via the Government Publishing Office FEDERAL RESERVE SYSTEM... Submission to OMB AGENCY: Board of Governors of the Federal Reserve System. SUMMARY: Notice is hereby given... into OMB's public docket files. The Federal Reserve may not conduct or sponsor, and the respondent...

  20. 76 FR 80364 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ... Primary and Secondary Emissions From Basic Oxygen Furnaces (Renewal) AGENCY: Environmental Protection... docket, go to www.regulations.gov . Title: NSPS for Primary and Secondary Emissions from Basic Oxygen... New Source Performance Standards (NSPS) for Primary and Secondary Emissions from Basic Oxygen...

  1. 77 FR 24720 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... Blood Components, Including Source Plasma AGENCY: Food and Drug Administration, HHS. ] ACTION: Notice... Components, Including Source Plasma.'' Also include the FDA docket number found in brackets in the heading of... Requirements for Blood and Blood Components, Including Source Plasma--(OMB Control Number 0910-NEW) FDA...

  2. 77 FR 29335 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-17

    ... reflects the Agency's tracking of information collected under FIFRA section 3 over the past three years... (OPP) Regulatory Public Docket (28221T), 1200 Pennsylvania Ave. NW., Washington, DC 20460, and (2) OMB...), Attention: Desk Officer for EPA, 725 17th Street NW., Washington, DC 20503. FOR FURTHER INFORMATION...

  3. 77 FR 38623 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-28

    ... Request; Emission Guidelines for Existing Other Solid Waste Incineration Units (Renewal) AGENCY... electronic docket, go to www.regulations.gov . Title: Emission Guidelines for Existing Other Solid Waste.... Respondents/Affected Entities: Owners or operators of other existing solid waste incinerators....

  4. 75 FR 78249 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-15

    ... Petitions for Stay of Action Subject to Section 505(q) of the Federal Food, Drug, and Cosmetic Act AGENCY... the Federal Food, Drug, and Cosmetic Act.'' Also include the FDA docket number found in brackets in... 505(q) of the Federal Food, Drug, and Cosmetic Act In the Federal Register of January 21, 2009 (74...

  5. 76 FR 30724 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-26

    ... Information Under the Federal Food, Drug, and Cosmetic Act AGENCY: Food and Drug Administration, HHS. ACTION... Cosmetic Act.'' Also include the FDA docket number found in brackets in the heading of this document. FOR... Industry Procedures for Section 513(g) Requests for Information under the Federal Food, Drug, and...

  6. 78 FR 37807 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-24

    ... Request; NESHAP for Commercial Ethylene Oxide Sterilization and Fumigation Operations (Renewal) AGENCY... information about the electronic docket, go to www.regulations.gov . Title: NESHAP for Commercial Ethylene... semiannually at a minimum. Respondents/Affected Entities: Owners or operator of commercial ethylene...

  7. 75 FR 80825 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-23

    ... Cooperation To Prevent Spread of Pet Food Related Diseases AGENCY: Food and Drug Administration, HHS. ACTION... to Prevent Spread of Pet Food Related Diseases. Also include the FDA docket number found in brackets... Diseases--(OMB Control Number 0910- New) In August 2008, FDA sponsored the ``Gateway to Food...

  8. 78 FR 3414 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-16

    ... Request; NSPS for Hospital/Medical/ Infectious Waste Incinerators (Renewal) AGENCY: Environmental... the electronic docket, go to www.regulations.gov . Title: NSPS for Hospital/Medical/Infectious Waste... disclose the information. Respondents/Affected Entities: Owners and operators of hospital, medical...

  9. 75 FR 53705 - Science and Technology (S&T) Directorate; Agency Information Collection Activities: Submission...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ...-53706] [FR Doc No: 2010-21783] DEPARTMENT OF HOMELAND SECURITY [Docket No. DHS-2010-0073] Science and... Collection Request for the Department of Homeland Security (DHS) Science and Technology Protected Repository for the Defense of Infrastructure Against Cyber Threats (PREDICT) Program AGENCY: Science...

  10. 76 FR 9612 - GE Hitachi Nuclear Energy; Acceptance for Docketing of an Application for Renewal of the U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-18

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION GE Hitachi Nuclear Energy; Acceptance for Docketing of an Application for Renewal of the U.S. Advanced Boiling Water Reactor Design Certification On December 7, 2010, GE Hitachi Nuclear Energy...

  11. 78 FR 35990 - All Operating Boiling-Water Reactor Licensees With Mark I And Mark II Containments; Docket Nos...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-14

    ... COMMISSION All Operating Boiling-Water Reactor Licensees With Mark I And Mark II Containments; Docket Nos... Licensees operate boiling-water reactors (BWRs) with Mark I and Mark II containment designs. II. The events... Boiling Water Reactors with Mark I and Mark II Containments'' (November 26, 2012). Option 2 in...

  12. 42 CFR 426.470 - Board's role in docketing and evaluating the acceptability of appeals of ALJ decisions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... DETERMINATIONS AND LOCAL COVERAGE DETERMINATIONS Review of an LCD § 426.470 Board's role in docketing and... the ALJ to send a copy of the ALJ's LCD review record (maintaining any sealed documents) to the Board... curiae. The Board may not allow participation by amicus participants in the review of an LCD....

  13. 42 CFR 426.470 - Board's role in docketing and evaluating the acceptability of appeals of ALJ decisions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... DETERMINATIONS AND LOCAL COVERAGE DETERMINATIONS Review of an LCD § 426.470 Board's role in docketing and... the ALJ to send a copy of the ALJ's LCD review record (maintaining any sealed documents) to the Board... curiae. The Board may not allow participation by amicus participants in the review of an LCD....

  14. 75 FR 43566 - University of Maryland; Notice of Acceptance for Docketing and Opportunity for Hearing on the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-26

    ... Review Process for License Renewal for Research Reactors'' (ISG) which can be obtained from the... University Training Reactor and Order Imposing Procedures for Access to Safeguards Information and Sensitive... for docketing. FOR FURTHER INFORMATION CONTACT: Spyros A. Traiforos, Project Manager, Research...

  15. 75 FR 65528 - Notice of Acceptance for Docketing of the Application, Notice of Opportunity for Hearing for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-25

    ... COMMISSION Notice of Acceptance for Docketing of the Application, Notice of Opportunity for Hearing for... law or fact to be raised or controverted. In addition, the requestor/petitioner shall provide a brief... information to show that a genuine dispute exists with the applicant on a material issue of law or...

  16. 75 FR 3493 - Notice of Acceptance for Docketing of the Application, Notice of Opportunity for Hearing for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Notice of Acceptance for Docketing of the Application, Notice of Opportunity for Hearing for Facility Operating License Nos. DPR-80 and DPR-82 for an Additional 20-Year Period; Pacific Gas & Electric Company, Diablo Canyon Nuclear Power...

  17. 78 FR 39342 - SHINE Medical Technologies, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-01

    ... Technologies, Inc. AGENCY: Nuclear Regulatory Commission. ACTION: Notice; acceptance for docketing. SUMMARY... SHINE Medical Technologies, Inc., is acceptable for docketing. ADDRESSES: Please refer to Docket ID NRC..., 2013, SHINE Medical Technologies (SHINE) filed with the U.S. Nuclear Regulatory Commission...

  18. 76 FR 43898 - Approval and Promulgation of State Implementation Plan Revisions; Infrastructure Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ...: Effective Date: This final rule is effective August 22, 2011. ADDRESSES: EPA has established a docket for this action under Docket ID No. EPA-R08-OAR-2010-0302. All documents in the docket are listed on the... Protection Agency (EPA). ACTION: Final rule. SUMMARY: EPA is approving and conditionally approving the...

  19. Low physical fitness levels in older adults with ID: results of the HA-ID study.

    PubMed

    Hilgenkamp, Thessa I M; van Wijck, Ruud; Evenhuis, Heleen M

    2012-01-01

    Physical fitness is as important to aging adults with ID as in the general population, but to date, the physical fitness levels of this group are unknown. Comfortable walking speed, muscle strength (grip strength), muscle endurance (30s Chair stand) and cardiorespiratory endurance (10 m incremental shuttle walking test) were tested in a sample of 1050 older adults with ID, and results were compared with reference values from the general population. Across all age ranges, approximately two-third of the entire study population scored 'below average' or 'impaired'. Even the youngest age groups (50-59 or 50-54 years) in this sample achieve similar or worse results than age groups 20-30 years older in the general population. Low physical fitness levels in older adults with ID demonstrate that this group is prone to unnecessary premature loss of functioning and health problems, and maintaining physical fitness should have priority in practice and policy.

  20. 77 FR 13074 - Opportunity for Designation in the Pocatello, ID; Evansville, IN; and Salt Lake City, UT Areas...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF AGRICULTURE Grain Inspection, Packers and Stockyards Administration Opportunity for Designation in the Pocatello, ID; Evansville, IN; and Salt Lake City, UT Areas; Request for Comments on the Official Agencies Servicing...

  1. Id1 regulates angiogenesis through transcriptional repression of thrombospondin-1.

    PubMed

    Volpert, Olga V; Pili, Roberto; Sikder, Hashmat A; Nelius, Thomas; Zaichuk, Tetiana; Morris, Chad; Shiflett, Clinton B; Devlin, Meghann K; Conant, Katherine; Alani, Rhoda M

    2002-12-01

    Id proteins are helix-loop-helix transcription factors that regulate tumor angiogenesis. In order to identify downstream effectors of Id1 involved in the regulation of angiogenesis, we performed PCR-select subtractive hybridization on wild-type and Id1 knockout mouse embryo fibroblasts (MEFs). Here we demonstrate that thrombospondin-1 (TSP-1), a potent inhibitor of angiogenesis, is a target of transcriptional repression by Id1. We also show that Id1-null MEFs secrete an inhibitor of endothelial cell migration, which is completely inactivated by depletion of TSP-1. Furthermore, in vivo studies revealed decreased neovascularization in matrigel assays in Id1-null mice compared to their wild-type littermates. This decrease was completely reversed by a TSP-1 neutralizing antibody. We conclude that TSP-1 is a major target for Id1 effects on angiogenesis.

  2. 76 FR 79173 - Registration Review; Pesticide Dockets Opened for Review and Comment, and Notice of Availability...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-21

    ... of Final Work Plans for Certain Pesticides AGENCY: Environmental Protection Agency (EPA). ACTION... program, EPA is ensuring that each pesticide's registration is based on current scientific and other... availability of amended final work plans for the registration review of the pesticides cryolite,...

  3. To ID or Not to ID? Changes in Classification Rates of Intellectual Disability Using "DSM-5"

    ERIC Educational Resources Information Center

    Papazoglou, Aimilia; Jacobson, Lisa A.; McCabe, Marie; Kaufmann, Walter; Zabel, T. Andrew

    2014-01-01

    The "Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition" ("DSM-5") diagnostic criteria for intellectual disability (ID) include a change to the definition of adaptive impairment. New criteria require impairment in one adaptive domain rather than two or more skill areas. The authors examined the diagnostic…

  4. Low Physical Fitness Levels in Older Adults with ID: Results of the HA-ID Study

    ERIC Educational Resources Information Center

    Hilgenkamp, Thessa I. M.; van Wijck, Ruud; Evenhuis, Heleen M.

    2012-01-01

    Physical fitness is as important to aging adults with ID as in the general population, but to date, the physical fitness levels of this group are unknown. Comfortable walking speed, muscle strength (grip strength), muscle endurance (30 s Chair stand) and cardiorespiratory endurance (10 m incremental shuttle walking test) were tested in a sample of…

  5. Comparative Evaluation of the BD Phoenix Yeast ID Panel and Remel RapID Yeast Plus System for Yeast Identification.

    PubMed

    Grant, Michelle L; Parajuli, Shobha; Deleon-Gonsalves, Raquel; Potula, Raghava; Truant, Allan L

    2016-01-01

    Becton Dickinson Phoenix Yeast ID Panel was compared to the Remel RapID Yeast Plus System using 150 recent clinical yeast isolates and the API 20C AUX system to resolve discrepant results. The concordance rate between the Yeast ID Panel and the RapID Yeast Plus System (without arbitration) was 93.3% with 97.3% (146/150) and 95.3% (143/150) of the isolates correctly identified by the Becton Dickinson Phoenix and the Remel RapID, respectively, with arbitration.

  6. Comparative Evaluation of the BD Phoenix Yeast ID Panel and Remel RapID Yeast Plus System for Yeast Identification

    PubMed Central

    Grant, Michelle L.; Parajuli, Shobha; Deleon-Gonsalves, Raquel; Potula, Raghava; Truant, Allan L.

    2016-01-01

    Becton Dickinson Phoenix Yeast ID Panel was compared to the Remel RapID Yeast Plus System using 150 recent clinical yeast isolates and the API 20C AUX system to resolve discrepant results. The concordance rate between the Yeast ID Panel and the RapID Yeast Plus System (without arbitration) was 93.3% with 97.3% (146/150) and 95.3% (143/150) of the isolates correctly identified by the Becton Dickinson Phoenix and the Remel RapID, respectively, with arbitration. PMID:27366167

  7. DriveID: safety innovation through individuation.

    PubMed

    Sawyer, Ben; Teo, Grace; Mouloua, Mustapha

    2012-01-01

    The driving task is highly complex and places considerable perceptual, physical and cognitive demands on the driver. As driving is fundamentally an information processing activity, distracted or impaired drivers have diminished safety margins compared with non- distracted drivers (Hancock and Parasuraman, 1992; TRB 1998 a & b). This competition for sensory and decision making capacities can lead to failures that cost lives. Some groups, teens and elderly drivers for example, have patterns of systematically poor perceptual, physical and cognitive performance while driving. Although there are technologies developed to aid these different drivers, these systems are often misused and underutilized. The DriveID project aims to design and develop a passive, automated face identification system capable of robustly identifying the driver of the vehicle, retrieve a stored profile, and intelligently prescribing specific accident prevention systems and driving environment customizations.

  8. Protocol for VOC-Arid ID remediation performance characterization

    SciTech Connect

    Tegner, B.J.; Hassig, N.L.; Last, G.V.

    1994-09-01

    The Volatile Organic Compound-Arid Integrated Demonstration (VOC-Arid ID) is a technology development program sponsored by the US Department of Energy`s Office of Technology Development that is targeted to acquire, develop, demonstrate, and deploy new technologies for the remediation of VOC contaminants in the soils and groundwaters of arid DOE sites. Technologies cannot be adequately evaluated unless sufficient site characterization and technology performance data have been collection and analyzed. The responsibility for identifying these data needs has been placed largely on the Principal Investigators (PIs) developing the remediation technology, who usually are not experts in site characterization or in identification of appropriate sampling, analysis, and monitoring techniques to support the field testing. This document provides a protocol for planning the collection of data before, during, and after a test of a new technology. This generic protocol provides the PIs and project managers with a set of steps to follow. The protocol is based on a data collection planning process called the Data Quality Objectives (DQO) process, which was originally developed by the US Environmental Protection Agency and has been expanded by DOE to support site cleanup decisions. The DQO process focuses on the quality and quantity of data required to make decision. Stakeholders to the decisions must negotiate such key inputs to the process as the decision rules that will be used and the acceptable probabilities of making decision errors.

  9. Final evaluation & test report for the standard waste box (docket 01-53-7A) type A packaging

    SciTech Connect

    KELLY, D L

    2001-10-15

    This report documents the U.S. Department of Transportation Specification 7A Type A compliance test and evaluation results of the Standard Waste Box. Testing and evaluation activities documented herein are on behalf of the U.S. Department of Energy-Headquarters, Office of Safety, Health and Security (EM-5), Germantown, Maryland. Duratek Federal Services, Inc., Northwest Operations performed an evaluation of the changes as documented herein under Docket 01-53-7A.

  10. 75 FR 36717 - Washington State University; Notice of Acceptance for Docketing and Opportunity for Hearing on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-28

    ... University (the licensee, WSU) to operate the Washington State University Modified TRIGA Nuclear Radiation... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY... Information and Sensitive Unclassified Non-Safeguards Information AGENCY: Nuclear Regulatory...

  11. 75 FR 12974 - Establishment of Class E Airspace; Hailey, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-18

    ... E airspace at Hailey, ID, to accommodate aircraft using the Area Navigation (RNAV) Global Positioning System (GPS) Standard Instrument Approach Procedure (SIAP) at Friedman Memorial Airport. This...

  12. Government Agencies

    DTIC Science & Technology

    1988-05-01

    manufacturers. The Navy has a major in- house design capability for ships; the government does not possess such a capability for aircraft or other weapon systems...the Coast Guard, government agencies acquire a wide variety of ships, ranging from sophisticated submarines and nuclear aircraft carriers to much...the initial phase a review was made of written material relating to government procedures in U.S. Government agencies for acquiring vessels, aircraft

  13. A Contextual Model for Identity Management (IdM) Interfaces

    ERIC Educational Resources Information Center

    Fuller, Nathaniel J.

    2014-01-01

    The usability of Identity Management (IdM) systems is highly dependent upon design that simplifies the processes of identification, authentication, and authorization. Recent findings reveal two critical problems that degrade IdM usability: (1) unfeasible techniques for managing various digital identifiers, and (2) ambiguous security interfaces.…

  14. An ID2-dependent mechanism for VHL inactivation in cancer.

    PubMed

    Lee, Sang Bae; Frattini, Veronique; Bansal, Mukesh; Castano, Angelica M; Sherman, Dan; Hutchinson, Keino; Bruce, Jeffrey N; Califano, Andrea; Liu, Guangchao; Cardozo, Timothy; Iavarone, Antonio; Lasorella, Anna

    2016-01-14

    Mechanisms that maintain cancer stem cells are crucial to tumour progression. The ID2 protein supports cancer hallmarks including the cancer stem cell state. HIFα transcription factors, most notably HIF2α (also known as EPAS1), are expressed in and required for maintenance of cancer stem cells (CSCs). However, the pathways that are engaged by ID2 or drive HIF2α accumulation in CSCs have remained unclear. Here we report that DYRK1A and DYRK1B kinases phosphorylate ID2 on threonine 27 (Thr27). Hypoxia downregulates this phosphorylation via inactivation of DYRK1A and DYRK1B. The activity of these kinases is stimulated in normoxia by the oxygen-sensing prolyl hydroxylase PHD1 (also known as EGLN2). ID2 binds to the VHL ubiquitin ligase complex, displaces VHL-associated Cullin 2, and impairs HIF2α ubiquitylation and degradation. Phosphorylation of Thr27 of ID2 by DYRK1 blocks ID2-VHL interaction and preserves HIF2α ubiquitylation. In glioblastoma, ID2 positively modulates HIF2α activity. Conversely, elevated expression of DYRK1 phosphorylates Thr27 of ID2, leading to HIF2α destabilization, loss of glioma stemness, inhibition of tumour growth, and a more favourable outcome for patients with glioblastoma.

  15. An ID2-dependent mechanism for VHL inactivation in cancer

    PubMed Central

    Lee, Sang Bae; Frattini, Veronique; Bansal, Mukesh; Castano, Angelica M.; Sherman, Dan; Hutchinson, Keino; Bruce, Jeffrey N.; Califano, Andrea; Liu, Guangchao; Cardozo, Timothy; Iavarone, Antonio; Lasorella, Anna

    2015-01-01

    Mechanisms that maintain cancer stem cells are crucial to tumor progression. The ID2 protein underpins cancer hallmarks including the cancer stem cell state. HIFα transcription factors, most notably HIF2α, are expressed in and required for maintenance of cancer stem cells (CSCs). However, the pathways that are engaged by ID2 or drive HIF2α accumulation in CSCs have remained unclear. We report that DYRK1A and DYRK1B kinases phosphorylate ID2 on Threonine-27 (T27). Hypoxia down regulates this phosphorylation via inactivation of DYRK1, whose activity is stimulated in normoxia by the oxygen sensing prolyl hydroxylase PHD1. ID2 binds to the VHL ubiquitin ligase complex, displaces VHL-associated Cullin-2, and impairs HIF2α ubiquitylation and degradation. Phosphorylation of ID2-T27 by DYRK1 blocks ID2-VHL interaction and preserves HIF2α ubiquitylation. In glioblastoma ID2 positively modulates HIF2α activity. Conversely, elevated expression of DYRK1 phosphorylates ID2- T27, leading to HIF2α destabilization, loss of glioma stemness, inhibition of tumor growth, and a more favorable outcome for patients with glioblastoma. PMID:26735018

  16. Optical ID tags for automatic vehicle identification and authentication

    NASA Astrophysics Data System (ADS)

    Javidi, Bahram; Pérez-Cabré, Elisabet; Millán, María S.

    2008-03-01

    We review the potential of optical techniques in security tasks and propose to combine some of them in the design of new optical ID tags for automatic vehicle identification and authentication. More specifically, we propose to combine visible and near infrared imaging, optical decryption, distortion-invariant ID tags, optoelectronic devices, coherent image processor, optical correlation, and multiple authenticators. A variety of images and signatures, including biometric and random sequences, can be combined in an optical ID tag for multifactor identification. Encryption of the information codified in the ID tag allows increasing security and deters from unauthorized usage of optical tags. A novel NIR ID tag is designed and built by using commonly available materials. The ID tag content cannot be visually perceived at naked eye; it cannot be copied, scanned, or captured by any conventional device. The identification process encompasses several steps such as detection, information decoding and verification which are all detailed in this work. Design of rotation and scale invariant ID tags is taken into account to achieve a correct authentication even if the ID tag is captured in different positions.

  17. 76 FR 29280 - Diablo Canyon Independent Spent Fuel Storage Installation; Notice of Docketing for Amendment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-20

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY... Request No. 2 to Special Nuclear Materials License No. 2511 AGENCY: Nuclear Regulatory Commission. ACTION..., Office of Nuclear Material Safety and Safeguards, U.S. Nuclear Regulatory Commission, Washington,...

  18. 7 CFR 1944.410 - Processing preapplications, applications, and completing grant dockets.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... SERVICE AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS (CONTINUED) HOUSING Self-Help Technical Assistance Grants § 1944.410 Processing preapplications, applications, and completing grant...-help assistance. Evidence should be provided that the communities support the activity and that...

  19. 7 CFR 1944.410 - Processing preapplications, applications, and completing grant dockets.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SERVICE AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS (CONTINUED) HOUSING Self-Help Technical Assistance Grants § 1944.410 Processing preapplications, applications, and completing grant...-help assistance. Evidence should be provided that the communities support the activity and that...

  20. 7 CFR 1944.410 - Processing preapplications, applications, and completing grant dockets.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... SERVICE AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS (CONTINUED) HOUSING Self-Help Technical Assistance Grants § 1944.410 Processing preapplications, applications, and completing grant...-help assistance. Evidence should be provided that the communities support the activity and that...

  1. Privacy Impact Assessment for the Federal Docket Management System/eRulemaking

    EPA Pesticide Factsheets

    This system collects the name and contact information for users who submit comments, in addition to agency users. Learn how the data is collected, how it will be used, access to the data, the purpose of data collection, and record retention policies.

  2. Final evaluation & test report for the standard waste box (docket 01-53-7A) type A packaging

    SciTech Connect

    KELLY, D.L.

    2001-08-15

    This report documents the U.S. Department of Transportation Specification 7A Type A (DOT-7A) compliance test and evaluation results of the Standard Waste Box (SWB). Testing and evaluation activities documented herein are on behalf of the U.S. Department of Energy-Headquarters (DOE-HQ), Office of Safety, Health and Security (EM-5), Germantown, Maryland. Dwatek Federal Services, Inc., Northwest Operations (DFSNW) performed an evaluation of the changes as documented herein under Docket 01-53-7A.

  3. 75 FR 51836 - Kentucky; Amendment No. 7 to Notice of a Major Disaster Declaration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-23

    ... [Federal Register Volume 75, Number 162 (Monday, August 23, 2010)] [Notices] [Pages 51836-51837] [FR Doc No: 2010-20775] DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Internal Agency Docket No. FEMA-1912-DR; Docket ID FEMA-2010-0002] Kentucky; Amendment No. 7 to Notice of a...

  4. 76 FR 43918 - Approval and Promulgation of State Implementation Plan Revisions; Infrastructure Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ..., 2011. ADDRESSES: EPA has established a docket for this action under Docket ID No. EPA-R08-OAR-2010-0298... Protection Agency (EPA). ACTION: Final rule. SUMMARY: EPA is partially approving and partially disapproving... or in hard copy at the Air Program, Environmental Protection Agency (EPA), Region 8, 1595...

  5. 416492 ORCID IDs and Counting: Uptake by the Astronomical Community

    NASA Astrophysics Data System (ADS)

    Holmquist, J.; Erdmann, C.; Damon, J.

    2015-04-01

    ORCID — an acronym short for Open Researcher and Contributor ID — is an international, interdisciplinary and community-driven effort to create and maintain a registry of persistent, unique identifiers for researchers and scholars. ORCID IDs are extremely important in the disambiguation of non-unique author names. They can also be embedded in key workflows, such as research profile maintenance, manuscript submissions and grant applications. Using several approaches to reach out to our users, we will report on ORCID ID uptake by the astronomical community.

  6. MicroRNAs and intellectual disability (ID) in Down syndrome, X-linked ID, and Fragile X syndrome

    PubMed Central

    Siew, Wei-Hong; Tan, Kai-Leng; Babaei, Maryam Abbaspour; Cheah, Pike-See; Ling, King-Hwa

    2013-01-01

    Intellectual disability (ID) is one of the many features manifested in various genetic syndromes leading to deficits in cognitive function among affected individuals. ID is a feature affected by polygenes and multiple environmental factors. It leads to a broad spectrum of affected clinical and behavioral characteristics among patients. Until now, the causative mechanism of ID is unknown and the progression of the condition is poorly understood. Advancement in technology and research had identified various genetic abnormalities and defects as the potential cause of ID. However, the link between these abnormalities with ID is remained inconclusive and the roles of many newly discovered genetic components such as non-coding RNAs have not been thoroughly investigated. In this review, we aim to consolidate and assimilate the latest development and findings on a class of small non-coding RNAs known as microRNAs (miRNAs) involvement in ID development and progression with special focus on Down syndrome (DS) and X-linked ID (XLID) [including Fragile X syndrome (FXS)]. PMID:23596395

  7. Id-1 and Id-2 genes and products as therapeutic targets for treatment of breast cancer and other types of carcinoma

    DOEpatents

    Desprez, Pierre-Yves; Campisi, Judith

    2014-09-30

    A method for treatment and amelioration of breast, cervical, ovarian, endometrial, squamous cells, prostate cancer and melanoma in a patient comprising targeting Id-1 or Id-2 gene expression with a delivery vehicle comprising a product which modulates Id-1 or Id-2 expression.

  8. RadNet Air Data From Idaho Falls, ID

    EPA Pesticide Factsheets

    This page presents radiation air monitoring and air filter analysis data for Idaho Falls, ID from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  9. Genetics Experts Unite to I.D. Unknown Katrina Victims

    MedlinePlus

    ... Current Issue Past Issues Research News From NIH Genetics Experts Unite to I.D. Unknown Katrina Victims ... in the recent Advances in molecular biology and genetics," says team member Stephen Sherry, Ph.D., of ...

  10. Defining the safe current limit for opening ID photon shutter

    SciTech Connect

    Seletskiy, S.

    2015-12-14

    The NSLS-II storage ring is protected from possible damage from insertion devices (IDs) synchrotron radiation by a dedicated active interlock system (AIS). It monitors electron beam position and angle and triggers beam drop if beam orbit exceeds the boundaries of pre-calculated active interlock envelope (AIE). The beamlines (BL) and beamline frontends (FE) are designed under assumption that the electron beam is interlocked within the AIE. For historic reasons the AIS engages the ID active interlock (AI-ID) at any non-zero beam current whenever the ID photon shutter (IDPS) is getting opened. Such arrangement creates major inconveniences for BLs commissioning. Apparently there is some IDPS safe current limit (SCL) under which the IDPS can be opened without interlocking the e-beam. The goal of this paper is to find such limit.

  11. RadNet Air Data From Boise, ID

    EPA Pesticide Factsheets

    This page presents radiation air monitoring and air filter analysis data for Boise, ID from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  12. 78 FR 773 - Hartford Financial Services Group, Inc., Commercial/Actuarial/Information Delivery Services (IDS...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-04

    ... Employment and Training Administration Hartford Financial Services Group, Inc., Commercial/Actuarial/ Information Delivery Services (IDS)/Corporate & Financial Reporting Group, Hartford, CT; Notice of Affirmative... (IDS)/Corporate & Financial Reporting group, Hartford, Connecticut (The Hartford-IDS Group)....

  13. Multimodal biometrics for identity documents (MBioID).

    PubMed

    Dessimoz, Damien; Richiardi, Jonas; Champod, Christophe; Drygajlo, Andrzej

    2007-04-11

    The MBioID initiative has been set up to address the following germane question: What and how biometric technologies could be deployed in identity documents in the foreseeable future? This research effort proposes to look at current and future practices and systems of establishing and using biometric identity documents (IDs) and evaluate their effectiveness in large-scale developments. The first objective of the MBioID project is to present a review document establishing the current state-of-the-art related to the use of multimodal biometrics in an IDs application. This research report gives the main definitions, properties and the framework of use related to biometrics, an overview of the main standards developed in the biometric industry and standardisation organisations to ensure interoperability, as well as some of the legal framework and the issues associated to biometrics such as privacy and personal data protection. The state-of-the-art in terms of technological development is also summarised for a range of single biometric modalities (2D and 3D face, fingerprint, iris, on-line signature and speech), chosen according to ICAO recommendations and availabilities, and for various multimodal approaches. This paper gives a summary of the main elements of that report. The second objective of the MBioID project is to propose relevant acquisition and evaluation protocols for a large-scale deployment of biometric IDs. Combined with the protocols, a multimodal database will be acquired in a realistic way, in order to be as close as possible to a real biometric IDs deployment. In this paper, the issues and solutions related to the acquisition setup are briefly presented.

  14. 77 FR 37077 - New Postal Product

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-20

    .... 1369] New Postal Product AGENCY: Postal Regulatory Commission. ACTION: Notice. SUMMARY: The Commission... new product. Id., Attachment B. The instant contract has been assigned Docket No. CP2012-33....

  15. 76 FR 3134 - Human Studies Review Board; Notice of Public Meeting; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-19

    ...The U.S. Environmental Protection Agency (EPA) published a document in the Federal Register of January 12, 2011, announcing the January 26, 2011 public meeting of the Human Studies Review Board. The document contained incorrect Docket ID...

  16. 78 FR 37164 - Land Acquisitions: Appeals of Land Acquisition Decisions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ...; Docket ID: BIA-2013-0005] RIN 1076-AF15 Land Acquisitions: Appeals of Land Acquisition Decisions AGENCY... applications to acquire land in trust under 25 CFR part 151. This document makes corrections to the...

  17. Improving Integration Effectiveness of ID Mapping Based Biological Record Linkage.

    PubMed

    Jamil, Hasan M

    2015-01-01

    Traditionally, biological objects such as genes, proteins, and pathways are represented by a convenient identifier, or ID, which is then used to cross reference, link and describe objects in biological databases. Relationships among the objects are often established using non-trivial and computationally complex ID mapping systems or converters, and are stored in authoritative databases such as UniGene, GeneCards, PIR and BioMart. Despite best efforts, such mappings are largely incomplete and riddled with false negatives. Consequently, data integration using record linkage that relies on these mappings produces poor quality of data, inadvertently leading to erroneous conclusions. In this paper, we discuss this largely ignored dimension of data integration, examine how the ubiquitous use of identifiers in biological databases is a significant barrier to knowledge fusion using distributed computational pipelines, and propose two algorithms for ad hoc and restriction free ID mapping of arbitrary types using online resources. We also propose two declarative statements for ID conversion and data integration based on ID mapping on-the-fly.

  18. Novel ID-based anti-collision approach for RFID

    NASA Astrophysics Data System (ADS)

    Zhang, De-Gan; Li, Wen-Bin

    2016-09-01

    Novel correlation ID-based (CID) anti-collision approach for RFID under the banner of the Internet of Things (IOT) has been presented in this paper. The key insights are as follows: according to the deterministic algorithms which are based on the binary search tree, we propose a method to increase the association between tags so that tags can initiatively send their own ID under certain trigger conditions, at the same time, we present a multi-tree search method for querying. When the number of tags is small, by replacing the actual ID with the temporary ID, it can greatly reduce the number of times that the reader reads and writes to tag's ID. Active tags send data to the reader by the way of modulation binary pulses. When applying this method to the uncertain ALOHA algorithms, the reader can determine the locations of the empty slots according to the position of the binary pulse, so it can avoid the decrease in efficiency which is caused by reading empty slots when reading slots. Theory and experiment show that this method can greatly improve the recognition efficiency of the system when applied to either the search tree or the ALOHA anti-collision algorithms.

  19. Id2 regulates hyporesponsive invariant natural killer T cells

    PubMed Central

    Stradner, Martin H; Cheung, Kitty P; Lasorella, Anna; Goldrath, Ananda W; D’Cruz, Louise M

    2016-01-01

    While the invariant natural killer T (iNKT)-cell response to primary stimulation with the glycolipid, α-galactosylceramide (αGalCer), is robust, the secondary response to this stimulus is muted resulting in a hyporesponsive state characterized by anti-inflammatory interleukin-10 (IL-10) production and high expression of programmed cell death 1 (PD1) and neuropilin 1 (NRP1). The E protein transcription factors and their negative regulators, the Id proteins, have previously been shown to regulate iNKT cell thymic development, subset differentiation and peripheral survival. Here, we provide evidence that the expression of the transcriptional regulator Id2 is downregulated upon stimulation of iNKT cells with their cognate antigen. Moreover, loss of Id2 expression by iNKT cells resulted in a hyporesponsive state, with splenic Id2-deficient iNKT cells expressing low levels of TBET, high levels of PD1 and NRP1 and production of IL-10 upon stimulation. We propose that downregulation of Id2 expression is an essential component of induction of the anti-inflammatory, hyporesponsive state in iNKT cells. PMID:26880074

  20. Physician integration and retention in a large IDS: economic implications.

    PubMed

    Lakin, J D

    2001-11-01

    To implement an effective physician recruitment and retention policy, Fairview Health Services, a large, regional integrated delivery system (IDS) headquartered in Minneapolis-St. Paul, Minnesota, conducted a study to determine the degree to which its physicians behaved as integral members of the IDS. The study primarily consisted of interviews with physicians and IDS clinical executives and their support staff. Responses were evaluated based on the Meyer and Allen three-component model of organizational commitment. Results provided a basis for recommending initiatives Fairview could undertake to increase physician commitment to the organization. Final recommendations included focusing recruitment efforts on older, more experienced physicians and reassessment of Fairview's hospital-centered approach to governance.

  1. Effect of ingredients on sensory profile of idli.

    PubMed

    Durgadevi, Manoharan; Shetty, Prathapkumar H

    2014-09-01

    Idli is a traditional fermented food and is consumed in India and Srilanka. The objective of the present study is to select the ingredients for optimum desirable product characteristics and to identify the optimum ratios of ingredients and fermentation time with respect to sensory attributes using Response Surface Methodology (RSM). The sensory attributes included were color, appearance, texture, taste and overall quality. Preliminary trials were conducted using five variants of rice and common black gram dhal before framing a model using Central Composite Rotatable Design (CCRD). From the study it was found that a desirable score of 0.7439 was obtained for sensory attributes of idli made with the ratio of 3: 1.475 for IR20 idli rice and ADT3 variety black gram (with husk removed after soaking) fermented for 10.2 h. Principal Component Analysis (PCA) helped to discriminate the samples and attributes within the data matrix, depending upon their inter relationships.

  2. Annual audits of IDS risk contract settlements improve payment accuracy.

    PubMed

    Pearce, J W

    1999-12-01

    Integrated delivery systems (IDSs) should conduct annual audits of payers' settlements under risk contracts to verify that the payer attributed the appropriate amounts of revenue and charged the appropriate claims expenses to the IDS. In particular, IDSs should verify that payers calculated revenues and expenses based on consistent member counts and that the determined commercial revenue was based on the actual premiums paid. IDSs also should determine whether payers have used appropriate demographic factors and countywide rates as a basis for determining Medicare revenue, charged the IDS for claims only for valid members, paid capitated providers the correct capitation amounts, and used appropriate historical data to estimate the amounts of incurred-but-not-reported claims attributed to the IDS.

  3. A Simple Quantum Integro-Differential Solver (SQuIDS)

    NASA Astrophysics Data System (ADS)

    Argüelles Delgado, Carlos A.; Salvado, Jordi; Weaver, Christopher N.

    2015-11-01

    Simple Quantum Integro-Differential Solver (SQuIDS) is a C++ code designed to solve semi-analytically the evolution of a set of density matrices and scalar functions. This is done efficiently by expressing all operators in an SU(N) basis. SQuIDS provides a base class from which users can derive new classes to include new non-trivial terms from the right hand sides of density matrix equations. The code was designed in the context of solving neutrino oscillation problems, but can be applied to any problem that involves solving the quantum evolution of a collection of particles with Hilbert space of dimension up to six.

  4. Installation, commissioning and performance of IDs installed at ALBA

    NASA Astrophysics Data System (ADS)

    Campmany, J.; Marcos, J.; Massana, V.; Becheri, F.; Gigante, J. V.; Colldelram, C.; Ribó, Ll

    2013-03-01

    The new synchrotron light source ALBA is currently starting regular operation. Up to 6 beamlines are using light produced by Insertion Devices. There are up to four types of IDs: 2 Apple-II undulators (EU62 and EU71) operating at low energies, one conventional wiggler (MPW80) operating in the range of 2 - 20 keV, two in-vacuum undulators (IVU21) operating in the range 5 - 30 keV and a superconducting wiggler (SCW30) operating in the range of (up to) 40 keV. The main IDs characteristics, their influence on the beam dynamics and a first characterization of their light will be presented.

  5. 78 FR 65555 - Establishment of Class E Airspace; Salmon, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-01

    ... airspace at the Salmon VHF Omni-Directional Radio Range/Distance Measuring Equipment (VOR/DME) navigation... the surface, at the Salmon VOR/DME navigation aid, Salmon, ID, to accommodate IFR aircraft under... within the scope of that authority as it establishes controlled airspace at the Salmon VOR/DME,...

  6. A Synergetic Model for Building an Intelligent Documentation System (IDS).

    ERIC Educational Resources Information Center

    Emdad, Ali

    1990-01-01

    Presents a conceptual framework for building an intelligent documentation system (IDS) for computer software by integrating hypermedia and expert systems technologies. The need for online computer documentation for end-users is discussed, and elements of the synergetic model are described, including knowledge representation, the hypermedia…

  7. Implementation of ID card system using optodigital information hiding scheme

    NASA Astrophysics Data System (ADS)

    Kim, Jung-Jin; Choi, Jin-Hyug; Kim, Eun-Soo

    2003-06-01

    In this paper, a new ID card system based-on the digital information hiding and optical extraction technique is suggested and implemented. In the information-hiding process, stego keys are digitally generated by using 2-D PRS and used to hide some specific data related to the card holders into their digital photo-image (cover image) in order to verify the ID cards. To extract the hidden data from the photo-image (stego image) in real-time, a matched filter-based optical correlator system is introduced. Optical correlation between the input stego image and the stego keys in the matched filter bank makes the sharp correlation peaks in the correlation plane only if the stego key hidden in the stego image is identically same with the stego key stored in the matched filter bank. This correlation peak signals and its position data can be used for verification of the ID card. In the experiment, a cover image of "Lena" is divided into 10 x 7 blocks and then, the stego key consisting of 64 x 64 pixels selected from 50 valid stego keys is embedded into the 3 different blocks of the cover image. Through the optical correlation between the "Lena" stego image and its valid stego key, resultant three correlation outputs and their position data are finally used for authentication. From these experimental results, a possibility of implementing a new ID card verification system using opto-digital information hiding and extraction scheme is suggested.

  8. idRHa+ProMod - Rail Hardening Control System

    NASA Astrophysics Data System (ADS)

    Ferro, L.

    2016-03-01

    idRHa+ProMod is the process control system developed by Primetals Technologies to foresee the thermo-mechanical evolution and micro-structural composition of rail steels subjected to slack quenching into idRHa+ Rail Hardening equipments in a simulation environment. This tool can be used both off-line or in-line, giving the user the chance to test and study the best cooling strategies or letting the automatic control system free to adjust the proper cooling recipe. Optimization criteria have been tailored in order to determine the best cooling conditions according to the metallurgical requirements imposed by the main rail standards and also taking into account the elastoplastic bending phenomena occurring during all stages of the head hardening process. The computational core of idRHa+ProMod is a thermal finite element procedure coupled with special algorithms developed to work out the main thermo-physical properties of steel, to predict the non-isothermal austenite decomposition into all the relevant phases and subsequently to evaluate the amount of latent heat of transformation released, the compound thermal expansion coefficient and the amount of plastic deformation in the material. Air mist and air blades boundary conditions have been carefully investigated by means of pilot plant tests aimed to study the jet impingement on rail surfaces and the cooling efficiency at all working conditions. Heat transfer coefficients have been further checked and adjusted directly on field during commissioning. idRHa+ is a trademark of Primetals Technologies Italy Srl

  9. Imagery Measures of Ego, Id, Superego, and Identity: Validity Studies.

    ERIC Educational Resources Information Center

    Cartwright, D.; DeBruin, J.

    1988-01-01

    Five validity studies of the id, ego, superego, and identity scales of the Study of Imagery are reported, using undergraduate students. Multistage Bonferroni procedures are used to evaluate the significance of results. The scales are related to each other and to toughmindedness, self-control, and behavioral conflict. (TJH)

  10. Enabling OpenID Authentication for VO-integrated Portals

    NASA Astrophysics Data System (ADS)

    Plante, R.; Yekkirala, V.; Baker, W.

    2012-09-01

    To support interoperating services that share proprietary data and other user-specific information, the VAO Project provides login services for browser-based portals built on the open standard, OpenID. To help portal developers take advantage of this service, we have developed a downloadable toolkit for integrating OpenID single sign-on support into any portal. This toolkit provides APIs in a few languages commonly used on the server-side as well as a command-line version for use in any language. In addition to describing how to use this toolkit, we also discuss the general VAO framework for single sign-on. While a portal may, if it wishes, support any OpenID provider, the VAO service provides a few extra features to support VO interoperability. This includes a portal's ability to retrieve (with the user's permission) an X.509 certificate representing the authenticated user so that the portal can access other restricted services on the user's behalf. Other standard features of OpenID allow portals to request other information about the user; this feature will be used in the future for sharing information about a user's group membership to enable sharing within a group of collaborating scientists.

  11. 76 FR 81371 - Approval and Disapproval and Promulgation of Implementation Plans; Texas; Infrastructure and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-28

    ...: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: The EPA is partially approving and partially... Deterioration (PSD) to include nitrogen oxides (NO X ) as an ozone precursor. This action is being taken under... established a docket for this action under Docket ID No. EPA-R06-OAR-2008-0638. All documents in the...

  12. 77 FR 54402 - Dichlorvos (DDVP); Order Denying NRDC's Objections on Remand

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ...: Environmental Protection Agency (EPA) ACTION: Final Order. SUMMARY: In this order, EPA denies an objection to a... docket for this action, identified by docket identification (ID) number EPA-HQ-OPP-2002-0302, is... action apply to me? In this document EPA denies an objection by the Natural Resources Defense...

  13. 77 FR 70752 - Notice of Decision Regarding Requests for a Waiver of the Renewable Fuel Standard

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-27

    ...: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: The Governors of several States requested that... established a docket for this action under Docket ID No. EPA-HQ-OAR-2012-0632. All documents and public... regulations through rulemaking actions to establish specific required renewable fuel volumes and...

  14. 77 FR 54601 - New Mexico; Major Disaster and Related Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... [Internal Agency Docket No. FEMA-4079-DR; Docket ID FEMA-2012-0002] New Mexico; Major Disaster and Related... Presidential declaration of a major disaster for the State of New Mexico (FEMA-4079-DR), dated August 24, 2012... Act''), as follows: I have determined that the damage in certain areas of the State of New...

  15. 75 FR 60 - Suspension of Community Eligibility

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-04

    ... Part 64 [Docket ID FEMA-2008-0020; Internal Agency Docket No. FEMA-8111] Suspension of Community... Insurance Program (NFIP), that are scheduled for suspension on the effective dates listed within this rule... floodplain management measures prior to the effective suspension date given in this rule, the suspension...

  16. 77 FR 29552 - Suspension of Community Eligibility

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    ... 44 CFR Part 64 [Docket ID FEMA-2012-0003; Internal Agency Docket No. FEMA-8231] Suspension of... Flood Insurance Program (NFIP) that are scheduled for suspension on the effective dates listed within... required floodplain management measures prior to the effective suspension date given in this rule,...

  17. 77 FR 39642 - Suspension of Community Eligibility

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-05

    ... 44 CFR Part 64 [Docket ID FEMA-2012-0003; Internal Agency Docket No. FEMA-8235] Suspension of... Flood Insurance Program (NFIP) that are scheduled for suspension on the effective dates listed within... required floodplain management measures prior to the effective suspension date given in this rule,...

  18. 77 FR 54600 - Ohio; Major Disaster and Related Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... [Internal Agency Docket No. FEMA-4077-DR; Docket ID FEMA-2012-0002] Ohio; Major Disaster and Related... Presidential declaration of a major disaster for the State of Ohio (FEMA-4077-DR), dated August 20, 2012, and... follows: I have determined that the damage in certain areas of the State of Ohio resulting from...

  19. 77 FR 56664 - Changes in Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ... [Docket ID FEMA-2012-0003; Internal Agency Docket No. FEMA-B-1262] Changes in Flood Hazard Determinations... where the addition or modification of Base Flood Elevations (BFEs), base flood depths, Special Flood... as flood hazard determinations), as shown on the Flood Insurance Rate Maps (FIRMs), and...

  20. 77 FR 54600 - Mississippi; Emergency and Related Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... Agency Docket No. FEMA-3348-EM; Docket ID FEMA-2011-0001] Mississippi; Emergency and Related... Presidential declaration of an emergency for the State of Mississippi (FEMA-3348-EM), dated August 28, 2012...: I have determined that the emergency conditions in certain areas of the State of...

  1. 77 FR 54599 - Mississippi; Amendment No. 1 to Notice of an Emergency Declaration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... [Internal Agency Docket No. FEMA-3348-EM; Docket ID FEMA-2012-0002] Mississippi; Amendment No. 1 to Notice...: This notice amends the notice of an emergency declaration for the State of Mississippi (FEMA-3348-EM... declaration for the [[Page 54600

  2. 76 FR 43912 - Approval and Promulgation of State Implementation Plan Revisions; Infrastructure Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ... August 22, 2011. ADDRESSES: EPA has established a docket for this action under Docket ID No. EPA-R08-OAR...: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: EPA is approving the State Implementation... addition, EPA is partially approving a June 14, 2010 SIP submittal from the State that revises the...

  3. Id proteins expression in prostate cancer: high-level expression of Id-4 in primary prostate cancer is associated with development of metastases.

    PubMed

    Yuen, Hiu-Fung; Chua, Chee-Wai; Chan, Yuen-Piu; Wong, Yong-Chuan; Wang, Xianghong; Chan, Kwok-Wah

    2006-07-01

    A major cause of treatment failure for prostate cancer is the development of androgen-independent metastatic disease. Id protein family, a group of basic helix-loop-helix transcription factors, has been shown to be involved in carcinogenesis and a prognostic marker in several types of human cancers. In this study, we examined the expressions of four Id proteins, Id-1, -2, -3 and -4, in 125 clinical prostate cancer specimens as well as 40 nodular hyperplasia specimens by immunohistochemistry. The expressions of Id proteins were correlated with Gleason grading and metastatic progress of the tumors. We found that Id proteins were dysregulated in prostate cancer. Id-1 and -2 expressions were elevated while Id-3 and -4 expressions were reduced in prostate cancers compared to nodular hyperplasia. Cytoplasmic staining of Id-1 (P=0.013) and nuclear staining of Id-2 (P=0.001) and Id-4 (P<0.001) were positively correlated with Gleason score. The results indicate that these Id proteins may play a positive role in the development of prostate cancer. In contrast, Id-3 might have an inverse relationship with prostate neoplastic transformation (P=0.002) and cancer progression (P=0.022). We found that Id-4 nuclear overexpression in the primary prostate cancers significantly increased the risks to the development of metastasis in the patients (odds ratio=3.215, 95% confidence interval=1.150-8.987, P=0.026). Our results suggest that in prostate cancer patients, differential Id proteins expressions may be a useful marker for poor prognosis, and Id-4 may be a potential prognostic marker for distant metastasis.

  4. Subgroups associated with lower physical fitness in older adults with ID: results of the HA-ID study.

    PubMed

    Hilgenkamp, Thessa I M; van Wijck, Ruud; Evenhuis, Heleen M

    2014-02-01

    Although physical fitness is generally very low in older adults with intellectual disabilities (ID), levels may differ across subgroups. It is important to identify which subgroups need to be targeted specifically in physical activity and fitness interventions and reference values. Physical fitness was measured with box-and-block-test, response-time-test, Berg-balance-scale, walking speed, grip strength, 30s-chair-stand, 10 m incremental-shuttle-walking test and the extended modified-back-saver-sit-and-reach-test in a large sample of older adults with ID (n=1050), and subgroups associated with lower physical fitness levels were identified applying multivariate linear regression analyses. Both fixed personal characteristics such as being older, being female, having more severe ID and having Down syndrome and modifiable or preventable factors such as physical activity levels, mobility impairments and a need of more intensive care, are independently associated with lower levels of multiple physical fitness components. This first study identifies subgroups of older adults with ID which require adapted reference values, and subgroups that need to be specifically targeted in fitness promotion programs.

  5. Comparison of BBL Crystal ANR ID Kit and API rapid ID 32 A for identification of anaerobic bacteria.

    PubMed

    Moll, W M; Ungerechts, J; Marklein, G; Schaal, K P

    1996-07-01

    BBL Crystal ANR ID Kit and the API System rapid ID 32 A are miniaturized identification systems for anaerobes using enzymatic tests. The incubation period of both systems is 4 hours. A comparative evaluation of the BBL Crystal Identification System Anaerobe ID Kit (Becton Dickinson Microbiology Systems, Cockeysville, USA) with anaerobes grown on Columbia and Schaedler agar plates (Becton Dickinson Microbiology Systems, Cockeysville, USA) and the API System rapid ID 32 A (BioMérieux SA, Lyon, France) with bacteria grown on Columbia agar (Becton Dickinson Microbiology Systems, Cockeysville, USA) which is recommended by the manufacturer as cultivation medium, was performed with 207 mostly fresh clinical anaerobe isolates, including 104 gram-negative bacilli, 12 gram-negative cocci, 15 gram-positive cocci, 14 gram-positive sporeforming bacilli and 62 representatives of gram-positive non-sporeforming bacilli. With supplemental testing the Crystal system with inocula from Columbia and Schaedler agar and API inoculates from Columbia agar identified to genus level 144 (69.6%), 152 (73.4%) and 109 (52.7%) isolates, respectively. Misidentification to genus level was found by Crystal from Columbia and Schaedler agar and by API from Columbia agar in 17 (8.2%), 15 (7.3%) and 12 (5.8%) isolates, respectively. 36 isolates were not determined to species level by classical anaerobic methods or the systems only identified to genus level. 26 anaerobes were not included in the database of the Crystal or API system. From the remaining 145 clinical isolates with supplemental testing, Crystal from Columbia and Schaedler agar plates correctly identified 91 (62.8%) and 102 (70.3%), respectively, and API, 69 (47.6%) isolates. For the correct identification to genus and species level of the 207 clinical isolates tested, the Crystal system from Columbia and Schaedler agar and API system from Columbia agar required supplemental testing, as specified by the manufacturer, for 39 (27.1%), 34 (22

  6. Evaluation of red blood cell and platelet antigen genotyping platforms (ID CORE XT/ID HPA XT) in routine clinical practice

    PubMed Central

    Finning, Kirstin; Bhandari, Radhika; Sellers, Fiona; Revelli, Nicoletta; Villa, Maria Antonietta; Muñiz-Díaz, Eduardo; Nogués, Núria

    2016-01-01

    Background High-throughput genotyping platforms enable simultaneous analysis of multiple polymorphisms for blood group typing. BLOODchip® ID is a genotyping platform based on Luminex® xMAP technology for simultaneous determination of 37 red blood cell (RBC) antigens (ID CORE XT) and 18 human platelet antigens (HPA) (ID HPA XT) using the BIDS XT software. Materials and methods In this international multicentre study, the performance of ID CORE XT and ID HPA XT, using the centres’ current genotyping methods as the reference for comparison, and the usability and practicality of these systems, were evaluated under working laboratory conditions. DNA was extracted from whole blood in EDTA with Qiagen methodologies. Ninety-six previously phenotyped/genotyped samples were processed per assay: 87 testing samples plus five positive controls and four negative controls. Results Results were available for 519 samples: 258 with ID CORE XT and 261 with ID HPA XT. There were three “no calls” that were either caused by human error or resolved after repeating the test. Agreement between the tests and reference methods was 99.94% for ID CORE XT (9,540/9,546 antigens determined) and 100% for ID HPA XT (all 4,698 alleles determined). There were six discrepancies in antigen results in five RBC samples, four of which (in VS, N, S and Doa) could not be investigated due to lack of sufficient sample to perform additional tests and two of which (in S and C) were resolved in favour of ID CORE XT (100% accuracy). The total hands-on time was 28–41 minutes for a batch of 16 samples. Compared with the reference platforms, ID CORE XT and ID HPA XT were considered simpler to use and had shorter processing times. Discussion ID CORE XT and ID HPA XT genotyping platforms for RBC and platelet systems were accurate and user-friendly in working laboratory settings. PMID:26674823

  7. Inhibitor of differentiation-4 (Id4) stimulates pigmentation in melanoma leading to histiocyte infiltration.

    PubMed

    DiVito, Kyle A; Trabosh, Valerie A; Chen, You-Shin; Simbulan-Rosenthal, Cynthia M; Rosenthal, Dean S

    2015-02-01

    TGF-β and the inhibitors of differentiation (Id) are linked. Smad7 and other TGF-β inhibitors can potently suppress melanomagenesis; however, little work examining Ids has been reported in melanoma, particularly for Id4. Here, we report that Id4, but not Id2 or Id3 expression, surprisingly, activated robust melanin production in xenografts of previously amelanotic (lacking pigment) 1205Lu/Smad7 (S7) cells. Fontana-Masson stain and de-novo expression of MART-1 and tyrosinase proteins confirmed melanin production. Additionally, pigment-laden CD163+ mouse histiocytes with areas of extensive necrosis were found throughout S7/Id4 tumors, but not in parental 1205Lu, S7/Id2 or S7Id3-derived tumors. Mechanistic investigation revealed increased nuclear M-microphthalmia-associated transcription factor (MITF) and MART-1 promoter activation following Id4 expression in 1205Lu and WM852 melanoma cells, suggesting broader implications for Id4 in melanin synthesis. In human tumors, melanin colocalized with Id4 expression establishing a correlation. Current chemotherapeutics for melanoma are only marginally effective. Immunotherapy provides the most promise, yet the role of innate immunity is poorly understood. Here, TGF-β suppression followed by Id4 expression results in extensive melanin synthesis and robust histiocyte recruitment following tumorigenesis, a novel role for Id4. Our results suggest that TGF-β suppression coupled with pigment overproduction triggers an innate immune response resulting in tumor necrosis.

  8. Entitlement Management: Ready to Enter the IdM Mainstream

    NASA Astrophysics Data System (ADS)

    Gebel, Gerry; Wang, Alice

    Externalizing authorization processing from business applications has been a goal for architects and developers for many years. Recent compliance demands for more granular access control and policy transparency have increased the urgency to adopt an architectural model where authorization and entitlement management are consumed as a service rather than embedded within business applications. Major software vendors, such as Microsoft, Oracle, and SAP, are making significant steps to separate IdM functionality, including entitlement management from application logic. The market has also responded with a plethora of products that provide entitlement management and authorization functionality for commercial or custom-built application environments. Finally, the Extensible Access Control Markup Language (XACML) has emerged as the consensus authorization standard being supported by a growing number of IT and application vendors. Collectively, these forces form the basis of a nascent IdM market segment referred to as entitlement management.

  9. Negotiating roadblocks to IDS-physician equity joint ventures.

    PubMed

    Dubow, S F; Benoff, M

    1998-09-01

    Integrated delivery systems (IDSs) may find that forming an equity joint venture relationship with a physician group practice is the best way to integrate physicians into their networks. IDSs have a choice between two basic equity structures: affiliated group practice, in which a management services organization (MSO) handles all practice management infrastructure and the physician group is a physician-only organization; and integrated group practice, in which the physician group encompasses both the physician practice and the administrative infrastructure. The choice of equity structure and how it should be implemented hinge on several legal issues, including the existence of a corporate-practice-of-medicine statute in the IDS's state, compliance with the Federal antikickback statute and Stark laws, and various issues regarding the IDS's tax-exempt status. IDSs also should consider pragmatic issues, particularly those associated with aligning the economic incentives of the two partners.

  10. Identity crisis? The need for systematic gene IDs.

    PubMed

    Parsons, Marilyn; Myler, Peter J; Berriman, Matthew; Roos, David S; Stuart, Kenneth D

    2011-05-01

    Recent years have seen an explosion in the availability of protozoan pathogen genome sequences. Although data regarding the underlying genome sequence remain relatively stable after the initial draft, understanding of specific gene function is increasing rapidly. This dichotomy is reflected in the relative stability of systematic gene identifiers (SysIDs(*)) in genome sequence databases, as compared to evolving and/or conflicting gene and gene product names. GenBank/EMBL/DDBJ accession numbers are important, but most protozoan parasite researchers use organism-based databases such as EuPathDB or GeneDB as their immediate resource for gene-based information because they not only provide sequence information but also functional information and links to references. Reference to SysIDs therefore provides a valuable bridge to this repository of information.

  11. Final evaluation report for Westinghouse Hanford Company, WRAP-1,208 liter waste drum, docket 94-35-7A, type A packaging

    SciTech Connect

    Kelly, D.L., Westinghouse Hanford

    1996-06-12

    This report documents the U.S. Department of Transportation Specification 7A Type A (DOT-7A) compliance test results of the Westinghouse Hanford Company, Waste Receiving and Processing Facility, Module 1 (WRAP-1) Drum. The WRAP-1 Drum was tested for DOE-HQ in August 1994, by Los Alamos National Laboratory, under docket number 94-35-7A. Additionally, comparison and evaluation of the approved, as-tested packaging configuration was performed by WHC in September 1995. The WRAP-1 Drum was evaluated against the performance of the DOT-17C, 208 1 (55-gal) steel drums tested and evaluated under dockets 89-13-7A/90-18-7A and 94-37-7A.

  12. Inhibitor of differentiation 4 (ID4) acts as an inhibitor of ID-1, -2 and -3 and promotes basic helix loop helix (bHLH) E47 DNA binding and transcriptional activity.

    PubMed

    Sharma, Pankaj; Chinaranagari, Swathi; Chaudhary, Jaideep

    2015-05-01

    The four known ID proteins (ID1-4, Inhibitor of Differentiation) share a homologous helix loop helix (HLH) domain and act as dominant negative regulators of basic-HLH transcription factors. ID proteins also interact with many non-bHLH proteins in complex networks. The expression of ID proteins is increasingly observed in many cancers. Whereas ID-1, ID-2 and ID-3, are generally considered as tumor promoters, ID4 on the contrary has emerged as a tumor suppressor. In this study we demonstrate that ID4 heterodimerizes with ID-1, -2 and -3 and promote bHLH DNA binding, essentially acting as an inhibitor of inhibitors of differentiation proteins. Interaction of ID4 was observed with ID1, ID2 and ID3 that was dependent on intact HLH domain of ID4. Interaction with bHLH protein E47 required almost 3 fold higher concentration of ID4 as compared to ID1. Furthermore, inhibition of E47 DNA binding by ID1 was restored by ID4 in an EMSA binding assay. ID4 and ID1 were also colocalized in prostate cancer cell line LNCaP. The alpha helix forming alanine stretch N-terminal, unique to HLH ID4 domain was required for optimum interaction. Ectopic expression of ID4 in DU145 prostate cancer line promoted E47 dependent expression of CDKNI p21. Thus counteracting the biological activities of ID-1, -2 and -3 by forming inactive heterodimers appears to be a novel mechanism of action of ID4. These results could have far reaching consequences in developing strategies to target ID proteins for cancer therapy and understanding biologically relevant ID-interactions.

  13. 78 FR 40142 - Office of Managing Director Creates Docket for Petitions Seeking Review of Application Fee Refund...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-03

    ... Communications Network, LLC Western Pacific Broadcast LLC Williston Community Broadcasting Corporation The... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS... Denials AGENCY: Federal Communications Commission. ACTION: Notice. SUMMARY: The Office of...

  14. Study of multilayer-reflected beam profiles and their coherence properties using beamlines ID19 (ESRF) and 32-ID (APS)

    SciTech Connect

    Rack, A.; Assoufid, L.; Dietsch, R.; Weitkamp, T.; Trabelsi, S. Bauer; Rack, T.; Siewert, F.; Kraemer, M.; Holz, Th.; Zanette, I.; Le, W.-K.; Cloetens, P.; Ziegler, E.

    2012-05-17

    The use of multilayer mirrors is an interesting alternative for reflective X-ray monochromatization with respect to reflection from crystal optics. The increased photon flux density due to the multilayers' larger bandwidth is of crucial importance for, e.g, full-field X-ray imaging applications. Drawbacks are the introduced modifications of the reflected beam profile as well as a certain loss of coherence, summarized as wavefront degradation. Our recent work has shown that the modification of the beam profile can vary with, e.g., the material composition of the coating applied. In order to verify our findings, a beamline round-robin has been initiated, comparing the wavefront profiles after reflection by selected multilayers at beamlines 32-ID (Advanced Photon Source) and ID19 (European Synchrotron Radiation Facility) with our initial results acquired at BM05 (ESRF) [1].

  15. 76 FR 66925 - Guidance for 1-Hour SO2

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-28

    ..., identified by Docket ID No. EPA-HQ- OAR-2010-1059, by one of the following methods: http://www.regulations... . Attention Docket ID No. EPA-HQ-OAR-2010-1059. Fax: (202) 566-9744. Attention Docket ID No. EPA-HQ-OAR- 2010-1059. Mail: Air Docket, Attention Docket ID No. EPA-HQ-OAR-2010- 1059, Environmental Protection...

  16. 78 FR 70569 - Technical Mapping Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-26

    ... Doc No: 2013-28313] DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Docket ID: FEMA-2013-0039] Technical Mapping Advisory Council AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice; Correction. SUMMARY: On November 1, 2013, the Federal Emergency Management Agency...

  17. PROCESS WATER BUILDING, TRA605. SUMP TANK PUMP. COMPARE WITH ID33G247. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PROCESS WATER BUILDING, TRA-605. SUMP TANK PUMP. COMPARE WITH ID-33-G-247. INL NEGATIVE NO. 4378. Unknown Photographer, 3/5/1952 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  18. Essential functions for ID proteins at multiple checkpoints in invariant NKT cell development.

    PubMed

    Verykokakis, Mihalis; Krishnamoorthy, Veena; Iavarone, Antonio; Lasorella, Anna; Sigvardsson, Mikael; Kee, Barbara L

    2013-12-15

    Invariant NKT (iNKT) cells display characteristics of both adaptive and innate lymphoid cells (ILCs). Like other ILCs, iNKT cells constitutively express ID proteins, which antagonize the E protein transcription factors that are essential for adaptive lymphocyte development. However, unlike ILCs, ID2 is not essential for thymic iNKT cell development. In this study, we demonstrated that ID2 and ID3 redundantly promoted iNKT cell lineage specification involving the induction of the signature transcription factor PLZF and that ID3 was critical for development of TBET-dependent NKT1 cells. In contrast, both ID2 and ID3 limited iNKT cell numbers by enforcing the postselection checkpoint in conventional thymocytes. Therefore, iNKT cells show both adaptive and innate-like requirements for ID proteins at distinct checkpoints during iNKT cell development.

  19. 45 CFR 630.645 - Federal agency or agency.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... or agency. Federal agency or agency means any United States executive department, military department... (including the Executive Office of the President), or any independent regulatory agency....

  20. 41 CFR 105-74.645 - Federal agency or agency.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ....645 Federal agency or agency. Federal agency or agency means any United States executive department... the executive branch (including the Executive Office of the President), or any independent...

  1. ETR BASEMENT, TRA642, INTERIOR. BASEMENT. CUBICLE INTERIOR (SEE PHOTOS ID33G101 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ETR BASEMENT, TRA-642, INTERIOR. BASEMENT. CUBICLE INTERIOR (SEE PHOTOS ID-33-G-101 AND ID-33-G-102) WITH TANK AND SODIUM-RELATED APPARATUS. CAMERA STANDS BEFORE ROLL-UP DOOR SHOWN IN PHOTO ID-33-G-101. INL NEGATIVE NO. HD24-3-3. Mike Crane, Photographer, 11/2000 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  2. Characterizing and Managing Intrusion Detection System (IDS) Alerts with Multi-Server/Multi-Priority Queuing Theory

    DTIC Science & Technology

    2014-12-26

    CHARACTERIZING AND MANAGING INTRUSION DETECTION SYSTEM (IDS) ALERTS WITH MULTI-SERVER/MULTI-PRIORITY...subject to copyright protection in the United States. AFIT-ENV-MS-14-D-24 CHARACTERIZING AND MANAGING INTRUSION DETECTION SYSTEM (IDS) ALERTS WITH...IDS) ALERTS WITH MULTI-SERVER/MULTI-PRIORITY QUEUING THEORY Christopher C. Olsen, BS Captain, USAF Approved

  3. 6 CFR 37.23 - Reissued REAL ID driver's licenses and identification cards.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 6 Domestic Security 1 2012-01-01 2012-01-01 false Reissued REAL ID driver's licenses and... SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum Documentation, Verification, and Card Issuance Requirements § 37.23 Reissued REAL ID driver's licenses and identification cards. (a)...

  4. 6 CFR 37.23 - Reissued REAL ID driver's licenses and identification cards.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 6 Domestic Security 1 2011-01-01 2011-01-01 false Reissued REAL ID driver's licenses and... SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum Documentation, Verification, and Card Issuance Requirements § 37.23 Reissued REAL ID driver's licenses and identification cards. (a)...

  5. 6 CFR 37.25 - Renewal of REAL ID driver's licenses and identification cards.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 6 Domestic Security 1 2012-01-01 2012-01-01 false Renewal of REAL ID driver's licenses and... SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum Documentation, Verification, and Card Issuance Requirements § 37.25 Renewal of REAL ID driver's licenses and identification cards. (a)...

  6. 6 CFR 37.25 - Renewal of REAL ID driver's licenses and identification cards.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 6 Domestic Security 1 2014-01-01 2014-01-01 false Renewal of REAL ID driver's licenses and... SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum Documentation, Verification, and Card Issuance Requirements § 37.25 Renewal of REAL ID driver's licenses and identification cards. (a)...

  7. 6 CFR 37.23 - Reissued REAL ID driver's licenses and identification cards.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Reissued REAL ID driver's licenses and... SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum Documentation, Verification, and Card Issuance Requirements § 37.23 Reissued REAL ID driver's licenses and identification cards. (a)...

  8. 6 CFR 37.25 - Renewal of REAL ID driver's licenses and identification cards.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Renewal of REAL ID driver's licenses and... SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum Documentation, Verification, and Card Issuance Requirements § 37.25 Renewal of REAL ID driver's licenses and identification cards. (a)...

  9. 6 CFR 37.25 - Renewal of REAL ID driver's licenses and identification cards.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 6 Domestic Security 1 2011-01-01 2011-01-01 false Renewal of REAL ID driver's licenses and... SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum Documentation, Verification, and Card Issuance Requirements § 37.25 Renewal of REAL ID driver's licenses and identification cards. (a)...

  10. 6 CFR 37.23 - Reissued REAL ID driver's licenses and identification cards.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 6 Domestic Security 1 2014-01-01 2014-01-01 false Reissued REAL ID driver's licenses and... SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum Documentation, Verification, and Card Issuance Requirements § 37.23 Reissued REAL ID driver's licenses and identification cards. (a)...

  11. 6 CFR 37.23 - Reissued REAL ID driver's licenses and identification cards.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 6 Domestic Security 1 2013-01-01 2013-01-01 false Reissued REAL ID driver's licenses and... SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum Documentation, Verification, and Card Issuance Requirements § 37.23 Reissued REAL ID driver's licenses and identification cards. (a)...

  12. 6 CFR 37.25 - Renewal of REAL ID driver's licenses and identification cards.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 6 Domestic Security 1 2013-01-01 2013-01-01 false Renewal of REAL ID driver's licenses and... SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum Documentation, Verification, and Card Issuance Requirements § 37.25 Renewal of REAL ID driver's licenses and identification cards. (a)...

  13. A Role for Id2 in Regulating Photic Entrainment of the Mammalian Circadian System

    PubMed Central

    Duffield, Giles E.; Watson, Nathan P.; Mantani, Akio; Peirson, Stuart N.; Robles-Murguia, Maricela; Loros, Jennifer J.; Israel, Mark A.; Dunlap, Jay C.

    2009-01-01

    Summary Inhibitor of DNA binding genes (Id1–Id4) encode helix-loop-helix (HLH) transcriptional repressors associated with development and tumorigenesis [1, 2], but little is known concerning the function(s) of these genes in normal adult animals. Id2 was identified in DNA microarray screens for rhythmically expressed genes [3–5], and further analysis revealed a circadian pattern of expression of all four Id genes in multiple tissues including the suprachiasmatic nucleus. To explore an in vivo function, we generated and characterized deletion mutations of Id2 and of Id4. Id2−/− mice exhibit abnormally rapid entrainment and an increase in the magnitude of the phase shift of the pacemaker. A significant proportion of mice also exhibit disrupted rhythms when maintained under constant darkness. Conversely, Id4−/− mice did not exhibit a noticeable circadian phenotype. In vitro studies using an mPer1 and an AVP promoter reporter revealed the potential for ID1, ID2, and ID3 proteins to interact with the canonical basic HLH clock proteins BMAL1 and CLOCK. These data suggest that the Id genes may be important for entrainment and operation of the mammalian circadian system, potentially acting through BMAL1 and CLOCK targets. PMID:19217292

  14. A role for Id2 in regulating photic entrainment of the mammalian circadian system.

    PubMed

    Duffield, Giles E; Watson, Nathan P; Mantani, Akio; Peirson, Stuart N; Robles-Murguia, Maricela; Loros, Jennifer J; Israel, Mark A; Dunlap, Jay C

    2009-02-24

    Inhibitor of DNA binding genes (Id1-Id4) encode helix-loop-helix (HLH) transcriptional repressors associated with development and tumorigenesis [1, 2], but little is known concerning the function(s) of these genes in normal adult animals. Id2 was identified in DNA microarray screens for rhythmically expressed genes [3-5], and further analysis revealed a circadian pattern of expression of all four Id genes in multiple tissues including the suprachiasmatic nucleus. To explore an in vivo function, we generated and characterized deletion mutations of Id2 and of Id4. Id2(-/-) mice exhibit abnormally rapid entrainment and an increase in the magnitude of the phase shift of the pacemaker. A significant proportion of mice also exhibit disrupted rhythms when maintained under constant darkness. Conversely, Id4(-/-) mice did not exhibit a noticeable circadian phenotype. In vitro studies using an mPer1 and an AVP promoter reporter revealed the potential for ID1, ID2, and ID3 proteins to interact with the canonical basic HLH clock proteins BMAL1 and CLOCK. These data suggest that the Id genes may be important for entrainment and operation of the mammalian circadian system, potentially acting through BMAL1 and CLOCK targets.

  15. 76 FR 43196 - Implementation of the Truth in Caller ID Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-20

    ...In this Report and Order (Order), the Commission adopts rules to implement the Truth in Caller ID Act of 2009 (Truth in Caller ID Act, or Act). The Truth in Caller ID Act, and the Commission's implementing rules, prohibit any person or entity from knowingly altering or manipulating caller identification information with the intent to defraud, cause harm, or wrongfully obtain anything of...

  16. Picture This: How to Establish an Effective School ID Card Program

    ERIC Educational Resources Information Center

    Finkelstein, David

    2013-01-01

    Most school districts do not have an ID card policy that everyone knows and follows, yet. many school districts are implementing ID card programs to address concerns about safety, efficiency, and convenience. A well-thought-out ID card program leads to greater security and smoother operations throughout the school and should thus be a priority.…

  17. Photometric variability of the Be star CoRoT-ID 102761769

    NASA Astrophysics Data System (ADS)

    Emilio, M.; Andrade, L.; Janot-Pacheco, E.; Baglin, A.; Gutiérrez-Soto, J.; Suárez, J. C.; de Batz, B.; Diago, P.; Fabregat, J.; Floquet, M.; Frémat, Y.; Huat, A. L.; Hubert, A. M.; Espinosa Lara, F.; Leroy, B.; Martayan, C.; Neiner, C.; Semaan, T.; Suso, J.

    2010-11-01

    Context. Classical Be stars are rapid rotators of spectral type late O to early A and luminosity class V-III, which exhibit Balmer emission lines and often a near infrared excess originating in an equatorially concentrated circumstellar envelope, both produced by sporadic mass ejection episodes. The causes of the abnormal mass loss (the so-called Be phenomenon) are as yet unknown. Aims: For the first time, we can now study in detail Be stars outside the Earth's atmosphere with sufficient temporal resolution. We investigate the variability of the Be Star CoRoT-ID 102761769 observed with the CoRoT satellite in the exoplanet field during the initial run. Methods: One low-resolution spectrum of the star was obtained with the INT telescope at the Observatorio del Roque de los Muchachos. A time series analysis was performed using both cleanest and singular spectrum analysis algorithms to the CoRoT light curve. To identify the pulsation modes of the observed frequencies, we computed a set of models representative of CoRoT-ID 102761769 by varying its main physical parameters inside the uncertainties discussed. Results: We found two close frequencies related to the star. They are 2.465 c d-1 (28.5 μHz) and 2.441 c d-1 (28.2 μHz). The precision to which those frequencies were found is 0.018 c d-1 (0.2 μHz). The projected stellar rotation was estimated to be 120 km s-1 from the Fourier transform of spectral lines. If CoRoT-ID 102761769 is a typical Galactic Be star it rotates near the critical velocity. The critical rotation frequency of a typical B5-6 star is about 3.5 c d-1 (40.5 μHz), which implies that the above frequencies are really caused by stellar pulsations rather than star's rotation. The CoRoT space mission was developed and is operated by the French space agency CNES, with participation of ESA's RSSD and Science Programmes, Austria, Belgium, Brazil, Germany, and Spain.

  18. Quadruplex Integrated DNA (QuID) Nanosensors for Monitoring Dopamine

    PubMed Central

    Morales, Jennifer M.; Skipwith, Christopher G.; Clark, Heather A.

    2015-01-01

    Dopamine is widely innervated throughout the brain and critical for many cognitive and motor functions. Imbalances or loss in dopamine transmission underlie various psychiatric disorders and degenerative diseases. Research involving cellular studies and disease states would benefit from a tool for measuring dopamine transmission. Here we show a Quadruplex Integrated DNA (QuID) nanosensor platform for selective and dynamic detection of dopamine. This nanosensor exploits DNA technology and enzyme recognition systems to optically image dopamine levels. The DNA quadruplex architecture is designed to be compatible in physically constrained environments (110 nm) with high flexibility, homogeneity, and a lower detection limit of 110 µM. PMID:26287196

  19. CRISP-ID: decoding CRISPR mediated indels by Sanger sequencing

    PubMed Central

    Dehairs, Jonas; Talebi, Ali; Cherifi, Yacine; Swinnen, Johannes V.

    2016-01-01

    The advent of next generation gene editing technologies has revolutionized the fields of genome engineering in allowing the generation of gene knockout models and functional gene analysis. However, the screening of resultant clones remains challenging due to the simultaneous presence of different indels. Here, we present CRISP-ID, a web application which uses a unique algorithm for genotyping up to three alleles from a single Sanger sequencing trace, providing a robust and readily accessible platform to directly identify indels and significantly speed up the characterization of clones. PMID:27363488

  20. 'My body is mine': Qualitatively exploring agency among internally displaced women participants in a small-group intervention in Leogane, Haiti.

    PubMed

    Logie, Carmen H; Daniel, CarolAnn

    2016-01-01

    The 2010 earthquake resulted in the breakdown of Haiti's social, economic and health infrastructure. Over one-quarter of a million people remain internally displaced (ID). ID women experience heightened vulnerability to intimate partner violence (IPV) due to increased poverty and reduced community networks. Scant research has examined experiences of IPV among ID women in post-earthquake Haiti. We conducted a qualitative study to explore the impact of participating in Famn an Aksyon Pou Santé Yo (FASY), a small-group HIV prevention intervention, on ID women's agency in Leogane, Haiti. We conducted four focus groups with ID women, FASY participants (n = 40) and in-depth individual interviews with peer health workers (n = 7). Our study was guided by critical ethnography and paid particular attention to power relations. Findings highlighted multiple forms of IPV (e.g., physical, sexual). Participants discussed processes of intrapersonal (confidence), interpersonal (communication), relational (support) and collective (women's rights) agency. Yet structural factors, including patriarchal gender norms and poverty, silenced IPV discussions and constrained women's agency. Findings suggest that agency among ID women is a multi-level, non-linear and incremental process. To effectively address IPV among ID women in Haiti, interventions should address structural contexts of gender inequity and poverty and concurrently facilitate multi-level processes of agency.

  1. Id3 induces an Elk-1-caspase-8-dependent apoptotic pathway in squamous carcinoma cells.

    PubMed

    Chen, You-Shin; Aubee, Joseph; DiVito, Kyle A; Zhou, Hengbo; Zhang, Weiyi; Chou, Fen-Pi; Simbulan-Rosenthal, Cynthia M; Rosenthal, Dean S

    2015-06-01

    Inhibitor of differentiation/DNA-binding (Id) proteins are helix-loop-helix (HLH) transcription factors. The Id protein family (Id1-Id4) mediates tissue homeostasis by regulating cellular processes including differentiation, proliferation, and apoptosis. Ids typically function as dominant negative HLH proteins, which bind other HLH proteins and sequester them away from DNA promoter regions. Previously, we have found that Id3 induced apoptosis in immortalized human keratinocytes upon UVB exposure, consistent with its role as a tumor suppressor. To investigate the role of Id3 in malignant squamous cell carcinoma (SCC) cells (A431), a tetracycline-regulated inducible system was used to induce Id3 in cell culture and mouse xenograft models. We found that upon Id3 induction, there was a decrease in cell number under low serum conditions, as well as in soft agar. Microarray, RT-PCR, immunoblot, siRNA, and inhibitor studies revealed that Id3 induced expression of Elk-1, an E-twenty-six (ETS)-domain transcription factor, inducing procaspase-8 expression and activation. Id3 deletion mutants revealed that 80 C-terminal amino acids, including the HLH, are important for Id3-induced apoptosis. In a mouse xenograft model, Id3 induction decreased tumor size by 30%. Using immunofluorescent analysis, we determined that the tumor size decrease was also mediated through apoptosis. Furthermore, we show that Id3 synergizes with 5-FU and cisplatin therapies for nonmelanoma skin cancer cells. Our studies have shown a molecular mechanism by which Id3 induces apoptosis in SCC, and this information can potentially be used to develop new treatments for SCC patients.

  2. Iron nanoparticles significantly affect the in vitro and in vivo expression of Id genes.

    PubMed

    Zou, Jinglu; Wang, Xin; Zhang, Ling; Wang, Jinke

    2015-03-16

    In recent DNA microarray studies, we found that the transcription of the Id3 gene was significantly down-regulated in five cell lines (RAW264.7, Hepa1-6, THP-1, HepG2, and HL7702) treated with two doses (50 and 100 μg/mL) of a DMSA-coated magnetite nanoparticle. Given the regulatory roles of Id genes in the cell cycle, growth, and differentiation, we wanted to do more investigations on the effect of the nanoparticle upon the Id genes. This study detected the expression of Id genes in six cell lines (the above cell lines plus HeLa) treated with the nanoparticle at the same doses using quantitative PCR. The results revealed that the expression of Id genes was significantly affected by the nanoparticle in these cell lines. Under each treatment, the Id3 gene was significantly (p < 0.01) down-regulated in all cell lines, the Id1 gene was significantly down-regulated in all cell lines except the RAW264.7 cells, and the Id2 gene was significantly down-regulated in the HepG2, HL7702, and HeLa cells. Because the Id1, Id2, and Id3 genes were significantly down-regulated in three liver-derived cell lines (Hepa1-6, HepG2, and HL7702) in both microarray and PCR detections, this study then detected the expression of Id genes in the liver tissues of mice that were intravenously injected with the nanoparticle at two doses (2 and 5 mg/kg body weight). The results revealed that the expression of Id1, Id2, and Id3 genes was also significantly down-regulated in the liver tissues under each treatment. Another Id gene, Id4, was also significantly regulated in some cells or liver tissues treated with the nanoparticle. These results reveal that the nanoparticle exerts a significant effect on the in vitro and in vivo expression of Id genes. This study thus provides new insights into the Id-related nanotoxicity of the nanoparticle and the close relationship between the regulation of Id genes and iron.

  3. DamID Analysis of Nuclear Organization in Caenorhabditis elegans.

    PubMed

    Gómez-Saldivar, Georgina; Meister, Peter; Askjaer, Peter

    2016-01-01

    The development of genomics and next generation sequencing platforms has dramatically improved our insight into chromatin structure and organization and its fine interplay with gene expression. The nuclear envelope has emerged as a key component in nuclear organization via extensive contacts between the genome and numerous proteins at the nuclear periphery. These contacts may have profound effects on gene expression as well as cell proliferation and differentiation. Indeed, their perturbations are associated with several human pathologies known as laminopathies or nuclear envelopathies. However, due to their dynamic behavior the contacts between nuclear envelope proteins and chromatin are challenging to identify, in particular in intact tissues. Here, we propose the DamID technique as an attractive method to globally characterize chromatin organization in the popular model organism Caenorhabditis elegans. DamID is based on the in vivo expression of a chromatin-associated protein of interest fused to the Escherichia coli DNA adenine methyltransferase, which produces unique identification tags at binding site in the genome. This marking is simple, highly specific and can be mapped by sensitive enzymatic and next generation sequencing approaches.

  4. Practical use of lens structures in ID documents

    NASA Astrophysics Data System (ADS)

    van den Berg, Jan

    2006-02-01

    Polymer ID-documents mostly are made of plastic foils which are laminated to one massive card by applying heat and pressure. During this lamination process, some structures can be transferred from the metal laminating plate to the card surface. These structures can be shaped in the form of a lens. Both are possible, positive as well as negative lens structures, for example in the form of lines or (micro) text. Also lens arrays of cylinder lenses can be made. The lens structures can be combined with the security design which is printed on the document, resulting in optically variable effects of moire patterns. Also these lens structures can be combined with laser engraving during the personalization of the document. In this way it is even possible to personalize the document with a stereo photo, the so called stereogram. The tactility of the structures on the ID-document, combined with the optical effects, makes these structures a very strong first line security feature. This kind of security features are completely integrated into the card body and combined with the personalization, which make them hard to manipulate by counterfeiters. Because of the fact that the human eye can handle images with a lot of noise, the optical quality of the lenses as well as the focal point seems to be less important for the most applications. Some applications need a rather high optical quality.

  5. ATF3 suppresses ESCC via downregulation of ID1

    PubMed Central

    Li, Jian; Yang, Zishan; Chen, Zhiuguo; Bao, Yonghua; Zhang, Huijuan; Fang, Xinhui; Yang, Wancai

    2016-01-01

    Esophageal cancer is one of the most prevalent forms of cancer and has a particularly high mortality rate due to early metastasis; however, the underlying mechanisms of its formation and progression remain unclear. The present study performed immunohistochemical analysis and observed that the expression of activating transcription factor 3 (ATF3) was reduced in esophageal squamous cell carcinoma (ESCC) in comparison with non-tumor adjacent tissues. By contrast, inhibitor of DNA binding 1 (ID1) was overexpressed in ESCC tissues, demonstrating an inverse correlation with ATF3 (P<0.01). In ESCC EC109 and KYSE450 cells lines, transfection with an ATF3-overexpression plasmid resulted in the inhibition of cell proliferation, motility and migration, which was associated with the induction of E-cadherin expression and inhibition of cyclin D1 and Twist. Notably, ATF3 exerted an inverse regulatory interaction with ID1. The results of the present study provide additional evidence of the tumor suppressive features of ATF3 and demonstrate a novel mechanism of ATF3-mediated inhibition of cancer metastasis in esophageal cancer. PMID:27602100

  6. ATF3 suppresses ESCC via downregulation of ID1.

    PubMed

    Li, Jian; Yang, Zishan; Chen, Zhiuguo; Bao, Yonghua; Zhang, Huijuan; Fang, Xinhui; Yang, Wancai

    2016-09-01

    Esophageal cancer is one of the most prevalent forms of cancer and has a particularly high mortality rate due to early metastasis; however, the underlying mechanisms of its formation and progression remain unclear. The present study performed immunohistochemical analysis and observed that the expression of activating transcription factor 3 (ATF3) was reduced in esophageal squamous cell carcinoma (ESCC) in comparison with non-tumor adjacent tissues. By contrast, inhibitor of DNA binding 1 (ID1) was overexpressed in ESCC tissues, demonstrating an inverse correlation with ATF3 (P<0.01). In ESCC EC109 and KYSE450 cells lines, transfection with an ATF3-overexpression plasmid resulted in the inhibition of cell proliferation, motility and migration, which was associated with the induction of E-cadherin expression and inhibition of cyclin D1 and Twist. Notably, ATF3 exerted an inverse regulatory interaction with ID1. The results of the present study provide additional evidence of the tumor suppressive features of ATF3 and demonstrate a novel mechanism of ATF3-mediated inhibition of cancer metastasis in esophageal cancer.

  7. 75 FR 23820 - Notice of Docketing of Amendment Request for Materials License No. SNM-2506; Northern States...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-04

    ... Company, a Minnesota Corporation; Prairie Island Independent Spent Fuel Storage Installation AGENCY: U.S... the Prairie Island Independent Spent Fuel Storage Installation (ISFSI), located at the Prairie Island... currently used at the Prairie Island ISFSI for storage of spent fuel with characteristics defined in...

  8. 75 FR 33653 - Exelon Nuclear Texas Holdings, LLC (Exelon) Acceptance for Docketing of an Application for an...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-14

    ... Exelon has submitted information in accordance with 10 CFR Parts 2 and 52 that is sufficiently complete... Commission's regulations, and that required notifications to other agencies and bodies have been made, the... problems in accessing the documents located in ADAMS, should contact the NRC Public Document Room staff...

  9. 21 CFR 10.20 - Submission of documents to Division of Dockets Management; computation of time; availability for...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., including quality control procedures. (d) Production, sales distribution, and similar information, except... readily available to the agency. (2) If a part of the material submitted is in a foreign language, it must... of literature or other material in a foreign language is to be accompanied by copies of the...

  10. Overexpression of Id-1 protein is a marker in colorectal cancer progression.

    PubMed

    Zhao, Zeng-Ren; Zhang, Zhi-Yong; Zhang, Hong; Jiang, Li; Wang, Ming-Wei; Sun, Xiao-Feng

    2008-02-01

    The inhibitor of differentiation/DNA binding 1 (Id-1), a negative regulator of basic helix-loop-helix transcription factors, plays an important role in the regulation of cell proliferation and differentiation. We examined the Id-1 expression by immunohistochemistry in 9 adenomas, 79 primary colorectal adenocarcinomas matched with 40 adjacent normal mucosa specimens and its relationship with clinicopathological factors. The Id-1 expression was increased in the carcinoma compared to the adjacent normal mucosa either in the unmatched and matched samples or to the adenoma. There was no significant difference in the Id-1 expression between normal mucosa and adenoma. The Id-1 expression of carcinoma was increased from Dukes' stages A to B, to C and to D. The cases with lymph node metastasis had a higher rate of a stronger Id-1 expression than those without lymph node metastasis. In conclusion, Id-1 overexpression plays an important role in colorectal cancer progression.

  11. Comparison of Perinatal Risk Factors Associated with Autism Spectrum Disorder (ASD), Intellectual Disability (ID), and Co-Occurring ASD and ID

    ERIC Educational Resources Information Center

    Schieve, Laura A.; Clayton, Heather B.; Durkin, Maureen S.; Wingate, Martha S.; Drews-Botsch, Carolyn

    2015-01-01

    While studies report associations between perinatal outcomes and both autism spectrum disorder (ASD) and intellectual disability (ID), there has been little study of ASD with versus without co-occurring ID. We compared perinatal risk factors among 7547 children in the 2006-2010 Autism and Developmental Disability Monitoring Network classified as…

  12. 40 CFR 36.645 - Federal agency or agency.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Federal agency or agency. Federal agency or agency means any United States executive department, military... executive branch (including the Executive Office of the President), or any independent regulatory agency....

  13. Microbe-ID: an open source toolbox for microbial genotyping and species identification.

    PubMed

    Tabima, Javier F; Everhart, Sydney E; Larsen, Meredith M; Weisberg, Alexandra J; Kamvar, Zhian N; Tancos, Matthew A; Smart, Christine D; Chang, Jeff H; Grünwald, Niklaus J

    2016-01-01

    Development of tools to identify species, genotypes, or novel strains of invasive organisms is critical for monitoring emergence and implementing rapid response measures. Molecular markers, although critical to identifying species or genotypes, require bioinformatic tools for analysis. However, user-friendly analytical tools for fast identification are not readily available. To address this need, we created a web-based set of applications called Microbe-ID that allow for customizing a toolbox for rapid species identification and strain genotyping using any genetic markers of choice. Two components of Microbe-ID, named Sequence-ID and Genotype-ID, implement species and genotype identification, respectively. Sequence-ID allows identification of species by using BLAST to query sequences for any locus of interest against a custom reference sequence database. Genotype-ID allows placement of an unknown multilocus marker in either a minimum spanning network or dendrogram with bootstrap support from a user-created reference database. Microbe-ID can be used for identification of any organism based on nucleotide sequences or any molecular marker type and several examples are provided. We created a public website for demonstration purposes called Microbe-ID (microbe-id.org) and provided a working implementation for the genus Phytophthora (phytophthora-id.org). In Phytophthora-ID, the Sequence-ID application allows identification based on ITS or cox spacer sequences. Genotype-ID groups individuals into clonal lineages based on simple sequence repeat (SSR) markers for the two invasive plant pathogen species P. infestans and P. ramorum. All code is open source and available on github and CRAN. Instructions for installation and use are provided at https://github.com/grunwaldlab/Microbe-ID.

  14. Microbe-ID: an open source toolbox for microbial genotyping and species identification

    PubMed Central

    Tabima, Javier F.; Everhart, Sydney E.; Larsen, Meredith M.; Weisberg, Alexandra J.; Kamvar, Zhian N.; Tancos, Matthew A.; Smart, Christine D.; Chang, Jeff H.

    2016-01-01

    Development of tools to identify species, genotypes, or novel strains of invasive organisms is critical for monitoring emergence and implementing rapid response measures. Molecular markers, although critical to identifying species or genotypes, require bioinformatic tools for analysis. However, user-friendly analytical tools for fast identification are not readily available. To address this need, we created a web-based set of applications called Microbe-ID that allow for customizing a toolbox for rapid species identification and strain genotyping using any genetic markers of choice. Two components of Microbe-ID, named Sequence-ID and Genotype-ID, implement species and genotype identification, respectively. Sequence-ID allows identification of species by using BLAST to query sequences for any locus of interest against a custom reference sequence database. Genotype-ID allows placement of an unknown multilocus marker in either a minimum spanning network or dendrogram with bootstrap support from a user-created reference database. Microbe-ID can be used for identification of any organism based on nucleotide sequences or any molecular marker type and several examples are provided. We created a public website for demonstration purposes called Microbe-ID (microbe-id.org) and provided a working implementation for the genus Phytophthora (phytophthora-id.org). In Phytophthora-ID, the Sequence-ID application allows identification based on ITS or cox spacer sequences. Genotype-ID groups individuals into clonal lineages based on simple sequence repeat (SSR) markers for the two invasive plant pathogen species P. infestans and P. ramorum. All code is open source and available on github and CRAN. Instructions for installation and use are provided at https://github.com/grunwaldlab/Microbe-ID. PMID:27602267

  15. 18 CFR 375.104 - Transfer of proceedings from other agencies to the Commission.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... those matters within his jurisdiction: (i) El Paso Eastern Co., et al., Docket No. CP 77-330, et al. (ii) Tenneco Atlantic Pipeline Co., et al., Docket No. CP 77-100, et al. (iii) Distrigas of Massachusetts Corp., et al., Docket No. CP 70-196, et al. (iv) Distrigas of Massachusetts Corp., et al., Docket No. CP...

  16. 18 CFR 375.104 - Transfer of proceedings from other agencies to the Commission.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... those matters within his jurisdiction: (i) El Paso Eastern Co., et al., Docket No. CP 77-330, et al. (ii) Tenneco Atlantic Pipeline Co., et al., Docket No. CP 77-100, et al. (iii) Distrigas of Massachusetts Corp., et al., Docket No. CP 70-196, et al. (iv) Distrigas of Massachusetts Corp., et al., Docket No. CP...

  17. ID-Check: Online Concealed Information Test Reveals True Identity.

    PubMed

    Verschuere, Bruno; Kleinberg, Bennett

    2016-01-01

    The Internet has already changed people's lives considerably and is likely to drastically change forensic research. We developed a web-based test to reveal concealed autobiographical information. Initial studies identified a number of conditions that affect diagnostic efficiency. By combining these moderators, this study investigated the full potential of the online ID-check. Participants (n = 101) tried to hide their identity and claimed a false identity in a reaction time-based Concealed Information Test. Half of the participants were presented with personal details (e.g., first name, last name, birthday), whereas the others only saw irrelevant details. Results showed that participants' true identity could be detected with high accuracy (AUC = 0.98; overall accuracy: 86-94%). Online memory detection can reliably and validly detect whether someone is hiding their true identity. This suggests that online memory detection might become a valuable tool for forensic applications.

  18. Automatic ID heat load generation in ANSYS code

    SciTech Connect

    Wang, Zhibi

    1992-04-30

    Detailed power density profiles are critical in the execution of a thermal analysis using a finite element (FE) code such as ANSYS. Unfortunately, as yet there is no easy way to directly input the precise power profiles into ANSYS. A straight-forward way to do this is to hand-calculate the power of each node or element and then type the data into the code. Every time a change is made to the FE model, the data must be recalculated and reentered. One way to solve this problem is to generate a set of discrete data, using another code such as PHOTON2, and curve-fit the data. Using curve-fitted formulae has several disadvantages. It is time consuming because of the need to run a second code for generation of the data, curve-fitting, and doing the data check, etc. Additionally, because there is no generality for different beamlines or different parameters, the above work must be repeated for each case. And, errors in the power profiles due to curve-fitting result in errors in the analysis. To solve the problem once and for all and with the capability to apply to any insertion device (ID), a program for ED power profile was written in ANSYS Parametric Design Language (APDL). This program is implemented as an ANSYS command with input parameters of peak magnetic field, deflection parameter, length of ID, and distance from the source. Once the command is issued, all the heat load will be automatically generated by the code.

  19. Underground Storage Tank Integrated Demonstration (UST-ID). Technology summary

    SciTech Connect

    Not Available

    1994-02-01

    The DOE complex currently has 332 underground storage tanks (USTs) that have been used to process and store radioactive and chemical mixed waste generated from weapon materials production. Very little of the over 100 million gallons of high-level and low-level radioactive liquid waste has been treated and disposed of in final form. Two waste storage tank design types are prevalent across the DOE complex: single-shell wall and double-shell wall designs. They are made of stainless steel, concrete, and concrete with carbon steel liners, and their capacities vary from 5000 gallons (19 m{sup 3}) to 10{sup 6} gallons (3785 m{sup 3}). The tanks have an overburden layer of soil ranging from a few feet to tens of feet. Responding to the need for remediation of tank waste, driven by Federal Facility Compliance Agreements (FFCAs) at all participating sites, the Underground Storage Tank Integrated Demonstration (UST-ID) Program was created by the US DOE Office of Technology Development in February 1991. Its mission is to focus the development, testing, and evaluation of remediation technologies within a system architecture to characterize, retrieve, treat to concentrate, and dispose of radioactive waste stored in USTs at DOE facilities. The ultimate goal is to provide safe and cost-effective solutions that are acceptable to the public and the regulators. The UST-ID has focused on five DOE locations: the Hanford Site, which is the host site, in Richland, Washington; the Fernald Site in Fernald, Ohio; the Idaho National Engineering Laboratory near Idaho Falls, Idaho; the Oak Ridge Reservation in Oak Ridge, Tennessee, and the Savannah River Site in Savannah River, South Carolina.

  20. Expression of ID family genes in the synovia from patients with rheumatoid arthritis.

    PubMed

    Sakurai, D; Yamaguchi, A; Tsuchiya, N; Yamamoto, K; Tokunaga, K

    2001-06-08

    Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by aggressive proliferation of synovial tissue leading to destruction of cartilage and bone. To identify molecules which play a crucial role for the pathogenesis, we compared mRNA expression pattern of RA synovium with that of osteoarthritis (OA), using the differential display. From the panel of differentially expressed genes, ID1 (inhibitor of differentiation 1) was considered to be particularly relevant to the pathogenesis of RA, because Id family genes have been shown to play a role in cell proliferation and angiogenesis. To examine whether the up-regulation of these genes is consistently observed in the patients with RA, mRNA levels of ID1 and ID3 in the synovial tissues from 13 patients with RA and 6 patients with OA were semi-quantitatively analyzed by RT-PCR. Mean mRNA levels of ID1 and ID3 were significantly elevated in RA synovia compared with OA by 8.6-fold (P = 0.0044) and 3.3-fold (P = 0.0085), respectively. Immunohistochemistry revealed striking staining of Id1 and Id3 in the endothelial cells, suggesting a possible role of Id in severe angiogenesis observed in RA. The expression of Id family genes in the synovium constitutes a new finding of particular interest. Their functional role as well as their contribution to the genetic susceptibility to RA requires further investigation.

  1. ID4 promotes AR expression and blocks tumorigenicity of PC3 prostate cancer cells.

    PubMed

    Komaragiri, Shravan Kumar; Bostanthirige, Dhanushka H; Morton, Derrick J; Patel, Divya; Joshi, Jugal; Upadhyay, Sunil; Chaudhary, Jaideep

    2016-09-09

    Deregulation of tumor suppressor genes is associated with tumorigenesis and the development of cancer. In prostate cancer, ID4 is epigenetically silenced and acts as a tumor suppressor. In normal prostate epithelial cells, ID4 collaborates with androgen receptor (AR) and p53 to exert its tumor suppressor activity. Previous studies have shown that ID4 promotes tumor suppressive function of AR whereas loss of ID4 results in tumor promoter activity of AR. Previous study from our lab showed that ectopic ID4 expression in DU145 attenuates proliferation and promotes AR expression suggesting that ID4 dependent AR activity is tumor suppressive. In this study, we examined the effect of ectopic expression of ID4 on highly malignant prostate cancer cell, PC3. Here we show that stable overexpression of ID4 in PC3 cells leads to increased apoptosis and decreased cell proliferation and migration. In addition, in vivo studies showed a decrease in tumor size and volume of ID4 overexpressing PC3 cells, in nude mice. At the molecular level, these changes were associated with increased androgen receptor (AR), p21, and AR dependent FKBP51 expression. At the mechanistic level, ID4 may regulate the expression or function of AR through specific but yet unknown AR co-regulators that may determine the final outcome of AR function.

  2. Overexpression of Id-1 is significantly associated with tumour angiogenesis in human pancreas cancers.

    PubMed

    Lee, K T; Lee, Y W; Lee, J K; Choi, S H; Rhee, J C; Paik, S S; Kong, G

    2004-03-22

    It has been suggested that Id-1 has a critical role in the tumour progression and aggressiveness of several human cancers. However, the clinicopathological and biological significance of Id-1 overexpression remains unclear in human primary cancer. To investigate the association between Id-1 expression and cell proliferation or tumour angiogenesis, we examined the cell cycle kinetic indices (the proliferation and apoptotic indices, PI and AI) and intratumoral microvessel density (MVD) in 65 human pancreatic cancers. We also investigated the relationship between its expression and various clinicopathological factors to determine the clinical significance of Id-1 overexpression. Out of a total 65 cases, 32 (49.3%) showed overexpression of Id-1 vs normal tissues. Id-1 expression was found to be significantly associated with MVD (P=0.002). In further analysis of subgroups with higher and lower Id-1 expression, tumours with higher Id-1 expression (scores 4 and 5) showed significantly higher MVD than tumours with lower expression of Id-1 (scores 2 and 3) (111.18+/-57.14 vs 64.13+/-28.19, P<0.001). However, no significant association was found between Id-1 overexpression and patient survival rate. No significant association was also found between Id-1 expression and cell cycle kinetic indices (PI or AI) in pancreatic cancer. Moreover, the overexpression of Id-1 protein was not correlated with any significant clinicopathologic factors. These findings indicate that Id-1 overexpression is closely related with tumour angiogenesis and a higher density of intratumoral vessel, but that it is not associated with a poorer prognosis of survival or a higher cell proliferative potential in human pancreatic cancer.

  3. Guaranty Agency Questionnaire.

    ERIC Educational Resources Information Center

    Leifman, Steven

    The extent to which guaranty agencies, lenders, and state secondary markets impose restrictions on Guaranteed Student Loan (GSL) borrowing that go beyond federal regulations was assessed through a survey of 53 guaranty agencies. Seventeen of the agencies imposed restrictions on GSLs that go beyond federal regulations, including not loaning to…

  4. 75 FR 56105 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... AGENCY Pesticide Products; Registration Applications AGENCY: Environmental Protection Agency (EPA... comments to docket ID number specified for the pesticide of interest as shown in the registration... of each registration application summary and may be contacted by telephone or e-mail. The...

  5. 76 FR 42707 - Amendment of OIG Hotline Allegation System (EPA-30)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-19

    ... AGENCY Amendment of OIG Hotline Allegation System (EPA-30) AGENCY: Environmental Protection Agency... System (EPA-30) to the Inspector General Enterprise Management System (IGEMS) Hotline Module. DATES.... ADDRESSES: Submit your comments, identified by Docket ID No. EPA-HQ- OEI-2011-0349, by one of the...

  6. 77 FR 25166 - EPA-New England Region I; Massachusetts Marine Sanitation Device Standard; Receipt of Petition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-27

    ... AGENCY EPA--New England Region I; Massachusetts Marine Sanitation Device Standard; Receipt of Petition AGENCY: Environmental Protection Agency (EPA). ACTION: Notice--Receipt of petition. SUMMARY: Notice is... your comments, identified by Docket ID No. EPA-R01- OW-2012-0201, by one of the following methods:...

  7. An improved smaller biotin ligase for BioID proximity labeling

    PubMed Central

    Kim, Dae In; Jensen, Samuel C.; Noble, Kyle A.; KC, Birendra; Roux, Kenneth H.; Motamedchaboki, Khatereh; Roux, Kyle J.

    2016-01-01

    The BioID method uses a promiscuous biotin ligase to detect protein–protein associations as well as proximate proteins in living cells. Here we report improvements to the BioID method centered on BioID2, a substantially smaller promiscuous biotin ligase. BioID2 enables more-selective targeting of fusion proteins, requires less biotin supplementation, and exhibits enhanced labeling of proximate proteins. Thus BioID2 improves the efficiency of screening for protein–protein associations. We also demonstrate that the biotinylation range of BioID2 can be considerably modulated using flexible linkers, thus enabling application-specific adjustment of the biotin-labeling radius. PMID:26912792

  8. 6 CFR 37.29 - Prohibition against holding more than one REAL ID card or more than one driver's license.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ID card or more than one driver's license. 37.29 Section 37.29 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum... REAL ID card or more than one driver's license. (a) An individual may hold only one REAL ID card....

  9. 6 CFR 37.29 - Prohibition against holding more than one REAL ID card or more than one driver's license.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ID card or more than one driver's license. 37.29 Section 37.29 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum... REAL ID card or more than one driver's license. (a) An individual may hold only one REAL ID card....

  10. 6 CFR 37.29 - Prohibition against holding more than one REAL ID card or more than one driver's license.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ID card or more than one driver's license. 37.29 Section 37.29 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum... REAL ID card or more than one driver's license. (a) An individual may hold only one REAL ID card....

  11. 6 CFR 37.29 - Prohibition against holding more than one REAL ID card or more than one driver's license.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ID card or more than one driver's license. 37.29 Section 37.29 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum... REAL ID card or more than one driver's license. (a) An individual may hold only one REAL ID card....

  12. 6 CFR 37.29 - Prohibition against holding more than one REAL ID card or more than one driver's license.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ID card or more than one driver's license. 37.29 Section 37.29 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY REAL ID DRIVER'S LICENSES AND IDENTIFICATION CARDS Minimum... REAL ID card or more than one driver's license. (a) An individual may hold only one REAL ID card....

  13. The Implementation of C-ID, R2D2 Model on Learning Reading Comprehension

    ERIC Educational Resources Information Center

    Rayanto, Yudi Hari; Rusmawan, Putu Ngurah

    2016-01-01

    The purposes of this research are to find out, (1) whether C-ID, R2D2 model is effective to be implemented on learning Reading comprehension, (2) college students' activity during the implementation of C-ID, R2D2 model on learning Reading comprehension, and 3) college students' learning achievement during the implementation of C-ID, R2D2 model on…

  14. Expression of Id-1 and VEGF in non-small cell lung cancer.

    PubMed

    Kim, Mee-Seon; Park, Tae-In; Lee, Yu-Mi; Jo, Young-Min; Kim, Sunzoo

    2013-01-01

    Angiogenesis is essential for invasive tumor growth and metastasis. Bevacizumab has been widely used for the treatment of non-small cell lung cancer (NSCLC). Various studies clearly demonstrate the relevance of Id-1 and VEGF in angiogenesis. The aim of this study was to establish the role of Id-1 expression in tumor progression and angiogenesis in relation to VEGF in NSCLC. Seventy five patients underwent surgery for lung cancers. The expressions of Id-1 and VEGF in NSCLC samples were determined by immunohistochemistry. Expression of Id-1 and VEGF showed a close correlation in NSCLC (p < 0.001). In addition, Id-1 strong expression group showed high incidence of metastasis in multivariate analysis (p = 0.028). Id-1 strong expression group had short metastasis-free survival (p = 0.008) and short recurrence-free survival (p = 0.027). Strong Id-1 expression in NSCLC had a poor prognosis in association with VEGF expression. Id-1 may function in tumor growth and progression via angiogenesis. Therefore, Id-1 is considered to be a candidate for new therapeutic target and a prognostic factor in NSCLC.

  15. A comprehensive protein-centric ID mapping service for molecular data integration

    PubMed Central

    Huang, Hongzhan; Suzek, Baris E.; Mazumder, Raja; Zhang, Jian; Chen, Yongxing; Wu, Cathy H.

    2011-01-01

    Motivation: Identifier (ID) mapping establishes links between various biological databases and is an essential first step for molecular data integration and functional annotation. ID mapping allows diverse molecular data on genes and proteins to be combined and mapped to functional pathways and ontologies. We have developed comprehensive protein-centric ID mapping services providing mappings for 90 IDs derived from databases on genes, proteins, pathways, diseases, structures, protein families, protein interaction, literature, ontologies, etc. The services are widely used and have been regularly updated since 2006. Availability: www.uniprot.org/mappingandproteininformation-resource.org/pirwww/search/idmapping.shtml Contact: huang@dbi.udel.edu PMID:21478197

  16. Idaho National Laboratory Supervisory Control and Data Acquisition Intrusion Detection System (SCADA IDS)

    SciTech Connect

    Jared Verba; Michael Milvich

    2008-05-01

    Current Intrusion Detection System (IDS) technology is not suited to be widely deployed inside a Supervisory, Control and Data Acquisition (SCADA) environment. Anomaly- and signature-based IDS technologies have developed methods to cover information technology-based networks activity and protocols effectively. However, these IDS technologies do not include the fine protocol granularity required to ensure network security inside an environment with weak protocols lacking authentication and encryption. By implementing a more specific and more intelligent packet inspection mechanism, tailored traffic flow analysis, and unique packet tampering detection, IDS technology developed specifically for SCADA environments can be deployed with confidence in detecting malicious activity.

  17. Id expression in amphioxus and lamprey highlights the role of gene cooption during neural crest evolution

    NASA Technical Reports Server (NTRS)

    Meulemans, Daniel; McCauley, David; Bronner-Fraser, Marianne

    2003-01-01

    Neural crest cells are unique to vertebrates and generate many of the adult structures that differentiate them from their closest invertebrate relatives, the cephalochordates. Id genes are robust markers of neural crest cells at all stages of development. We compared Id gene expression in amphioxus and lamprey to ask if cephalochordates deploy Id genes at the neural plate border and dorsal neural tube in a manner similar to vertebrates. Furthermore, we examined whether Id expression in these cells is a basal vertebrate trait or a derived feature of gnathostomes. We found that while expression of Id genes in the mesoderm and endoderm is conserved between amphioxus and vertebrates, expression in the lateral neural plate border and dorsal neural tube is a vertebrate novelty. Furthermore, expression of lamprey Id implies that recruitment of Id genes to these cells occurred very early in the vertebrate lineage. Based on expression in amphioxus we postulate that Id cooption conferred sensory cell progenitor-like properties upon the lateral neurectoderm, and pharyngeal mesoderm-like properties upon cranial neural crest. Amphioxus Id expression is also consistent with homology between the anterior neurectoderm of amphioxus and the presumptive placodal ectoderm of vertebrates. These observations support the idea that neural crest evolution was driven in large part by cooption of multipurpose transcriptional regulators from other tissues and cell types.

  18. Id-1 is not expressed in the luminal epithelial cells of mammary glands

    PubMed Central

    Uehara, Norihisa; Chou, Yu-Chien; Galvez, Jose J; de-Candia, Paola; Cardiff, Robert D; Benezra, Robert; Shyamala, Gopalan

    2003-01-01

    Background The family of inhibitor of differentiation/DNA binding (Id) proteins is known to regulate development in several tissues. One member of this gene family, Id-1, has been implicated in mammary development and carcinogenesis. Mammary glands contain various cell types, among which the luminal epithelial cells are primarily targeted for proliferation, differentiation and carcinogenesis. Therefore, to assess the precise significance of Id-1 in mammary biology and carcinogenesis, we examined its cellular localization in vivo using immunohistochemistry. Methods Extracts of whole mammary glands from wild type and Id-1 null mutant mice, and tissue sections from paraffin-embedded mouse mammary glands from various developmental stages and normal human breast were subjected to immunoblot and immunohistochemical analyses, respectively. In both these procedures, an anti-Id-1 rabbit polyclonal antibody was used for detection of Id-1. Results In immunoblot analyses, using whole mammary gland extracts, Id-1 was detected. In immunohistochemical analyses, however, Id-1 was not detected in the luminal epithelial cells of mammary glands during any stage of development, but it was detected in vascular endothelial cells. Conclusion Id-1 is not expressed in the luminal epithelial cells of mammary glands. PMID:12631395

  19. 22 CFR 312.645 - Federal agency or agency.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... ASSISTANCE) Definitions § 312.645 Federal agency or agency. Federal agency or agency means any United States... other establishment in the executive branch (including the Executive Office of the President), or...

  20. 29 CFR 94.645 - Federal agency or agency.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) Definitions § 94.645 Federal agency or agency. Federal agency or agency means any United States executive... establishment in the executive branch (including the Executive Office of the President), or any...

  1. 29 CFR 94.645 - Federal agency or agency.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... ASSISTANCE) Definitions § 94.645 Federal agency or agency. Federal agency or agency means any United States... other establishment in the executive branch (including the Executive Office of the President), or...

  2. 22 CFR 312.645 - Federal agency or agency.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... ASSISTANCE) Definitions § 312.645 Federal agency or agency. Federal agency or agency means any United States... other establishment in the executive branch (including the Executive Office of the President), or...

  3. 36 CFR 1212.645 - Federal agency or agency.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) Definitions § 1212.645 Federal agency or agency. Federal agency or agency means any United States executive... establishment in the executive branch (including the Executive Office of the President), or any...

  4. 29 CFR 94.645 - Federal agency or agency.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... ASSISTANCE) Definitions § 94.645 Federal agency or agency. Federal agency or agency means any United States... other establishment in the executive branch (including the Executive Office of the President), or...

  5. Robust Speech Processing & Recognition: Speaker ID, Language ID, Speech Recognition/Keyword Spotting, Diarization/Co-Channel/Environmental Characterization, Speaker State Assessment

    DTIC Science & Technology

    2015-10-01

    insight into a low resource languages ,” Transactions on Machine Learning and Artificial Intelligence, 2(4), Aug. 2014, 115-126. [4] Q. Zheng, G. Liu...by a person is a rich and valuable piece of information for several applications such as health monitoring, second language learning or language ...ROBUST SPEECH PROCESSING & RECOGNITION: SPEAKER ID, LANGUAGE ID, SPEECH RECOGNITION/KEYWORD SPOTTING, DIARIZATION/CO- CHANNEL/ENVIRONMENTAL

  6. Vision robot with rotational camera for searching ID tags

    NASA Astrophysics Data System (ADS)

    Kimura, Nobutaka; Moriya, Toshio

    2008-02-01

    We propose a new concept, called "real world crawling", in which intelligent mobile sensors completely recognize environments by actively gathering information in those environments and integrating that information on the basis of location. First we locate objects by widely and roughly scanning the entire environment with these mobile sensors, and we check the objects in detail by moving the sensors to find out exactly what and where they are. We focused on the automation of inventory counting with barcodes as an application of our concept. We developed "a barcode reading robot" which autonomously moved in a warehouse. It located and read barcode ID tags using a camera and a barcode reader while moving. However, motion blurs caused by the robot's translational motion made it difficult to recognize the barcodes. Because of the high computational cost of image deblurring software, we used the pan rotation of the camera to reduce these blurs. We derived the appropriate pan rotation velocity from the robot's translational velocity and from the distance to the surfaces of barcoded boxes. We verified the effectiveness of our method in an experimental test.

  7. Molecular characterization of lactobacilli isolated from fermented idli batter

    PubMed Central

    Agaliya, Perumal Jayaprabha; Jeevaratnam, Kadirvelu

    2013-01-01

    Lactic acid bacteria are non pathogenic organism widely distributed in nature typically involved in a large number of spontaneous food fermentation. The purpose of this study was to characterize the bacteriocinogenic lactobacilli from fermented idli batter which can find application in biopreservation and biomedicine. Eight most promising lactobacilli were chosen from twenty two isolates based on their spectrum of activity against other lactic acid bacteria and pathogens. The eight lactobacilli were characterized based on the various classical phenotypic tests, physiological tests and biochemical tests including various carbohydrate utilization profiles. All isolates were homo fermentative, catalase, and gelatin negative. Molecular characterization was performed by RAPD, 16S rRNA analysis, 16S ARDRA, and Multiplex PCR for species identification. RAPD was carried out using the primer R2 and M13. Five different clusters were obtained based on RAPD indicating strain level variation. 16S rRNA analysis showed 99 to 100% homology towards Lactobacillus plantarum. The restriction digestion pattern was similar for all the isolates with the restriction enzyme AluI. The subspecies were identified by performing Multiplex PCR using species specific primer. Among the five clusters, three clusters were clearly identified as Lactobacillus plantarum subsp. plantarum, Lactobacillus pentosus, and Lactobacillus plantarum subsp. argentoratensis. PMID:24688512

  8. Pros and Cons of ID vs. 3D Modeling

    NASA Technical Reports Server (NTRS)

    Klimchuk, James A.

    2012-01-01

    Advances in computing capability have led to tremendous improvements in 3D modeling. Entire active regions are being simulated in what might be described as a first principles way, in which plasma heating is treated self consistently rather than through the specification of heating functions. There are limitations to this approach, however, as actual heating mechanisms on the Sun involve spatial scales orders of magnitude smaller than what these simulations can resolve. Other simulations begin to resolve these scales, but they only treat a tiny volume and do not include the all important coupling with larger scales or with other parts of the atmosphere, and so cannot be readily compared with observations. Finally, ID hydrodynamic models capture the field-aligned evolution of the plasma extremely well and are ideally suited for data comparison, but they treat the heating in a totally ad hoc manner. All of these approaches have important contributions to make, but we must be aware of their limitations. I will highlight some of the strengths. and weaknesses of each.

  9. Minimum wafer thickness by rotated ingot ID wafering. [Inner Diameter

    NASA Technical Reports Server (NTRS)

    Chen, C. P.; Leipold, M. H.

    1984-01-01

    The efficient utilization of materials is critical to certain device applications such as silicon for photovoltaics or diodes and gallium-gadolinium-garnet for memories. A variety of slicing techniques has been investigated to minimize wafer thickness and wafer kerf. This paper presents the results of analyses of ID wafering of rotated ingots based on predicted fracture behavior of the wafer as a result of forces during wafering and the properties of the device material. The analytical model indicated that the minimum wafer thickness is controlled by the depth of surface damage and the applied cantilever force. Both of these factors should be minimized. For silicon, a minimum thickness was found to be approximately 200 x 10 - 6th m for conventional sizes of rotated ingot wafering. Fractures through the thickness of the wafer rather than through the center supporting column were found to limit the minimum wafer thickness. The model suggested that the use of a vacuum chuck on the wafer surface to enhance cleavage fracture of the center supporting core and, with silicon, by using 111-line-type ingots could have potential for reducing minimum wafer thickness.

  10. A neural-visualization IDS for honeynet data.

    PubMed

    Herrero, Álvaro; Zurutuza, Urko; Corchado, Emilio

    2012-04-01

    Neural intelligent systems can provide a visualization of the network traffic for security staff, in order to reduce the widely known high false-positive rate associated with misuse-based Intrusion Detection Systems (IDSs). Unlike previous work, this study proposes an unsupervised neural models that generate an intuitive visualization of the captured traffic, rather than network statistics. These snapshots of network events are immensely useful for security personnel that monitor network behavior. The system is based on the use of different neural projection and unsupervised methods for the visual inspection of honeypot data, and may be seen as a complementary network security tool that sheds light on internal data structures through visual inspection of the traffic itself. Furthermore, it is intended to facilitate verification and assessment of Snort performance (a well-known and widely-used misuse-based IDS), through the visualization of attack patterns. Empirical verification and comparison of the proposed projection methods are performed in a real domain, where two different case studies are defined and analyzed.

  11. Six steps in quality intervention development (6SQuID)

    PubMed Central

    Wight, Daniel; Wimbush, Erica; Jepson, Ruth; Doi, Lawrence

    2016-01-01

    Improving the effectiveness of public health interventions relies as much on the attention paid to their design and feasibility as to their evaluation. Yet, compared to the vast literature on how to evaluate interventions, there is little to guide researchers or practitioners on how best to develop such interventions in practical, logical, evidence based ways to maximise likely effectiveness. Existing models for the development of public health interventions tend to have a strong social-psychological, individual behaviour change orientation and some take years to implement. This paper presents a pragmatic guide to six essential Steps for Quality Intervention Development (6SQuID). The focus is on public health interventions but the model should have wider applicability. Once a problem has been identified as needing intervention, the process of designing an intervention can be broken down into six crucial steps: (1) defining and understanding the problem and its causes; (2) identifying which causal or contextual factors are modifiable: which have the greatest scope for change and who would benefit most; (3) deciding on the mechanisms of change; (4) clarifying how these will be delivered; (5) testing and adapting the intervention; and (6) collecting sufficient evidence of effectiveness to proceed to a rigorous evaluation. If each of these steps is carefully addressed, better use will be made of scarce public resources by avoiding the costly evaluation, or implementation, of unpromising interventions. PMID:26573236

  12. Generating unique IDs from patient identification data using security models

    PubMed Central

    Mohammed, Emad A.; Slack, Jonathan C.; Naugler, Christopher T.

    2016-01-01

    Background: The use of electronic health records (EHRs) has continued to increase within healthcare systems in the developed and developing nations. EHRs allow for increased patient safety, grant patients easier access to their medical records, and offer a wealth of data to researchers. However, various bioethical, financial, logistical, and information security considerations must be addressed while transitioning to an EHR system. The need to encrypt private patient information for data sharing is one of the foremost challenges faced by health information technology. Method: We describe the usage of the message digest-5 (MD5) and secure hashing algorithm (SHA) as methods for encrypting electronic medical data. In particular, we present an application of the MD5 and SHA-1 algorithms in encrypting a composite message from private patient information. Results: The results show that the composite message can be used to create a unique one-way encrypted ID per patient record that can be used for data sharing. Conclusion: The described software tool can be used to share patient EMRs between practitioners without revealing patients identifiable data. PMID:28163977

  13. Molecular characterization of lactobacilli isolated from fermented idli batter.

    PubMed

    Agaliya, Perumal Jayaprabha; Jeevaratnam, Kadirvelu

    2013-12-01

    Lactic acid bacteria are non pathogenic organism widely distributed in nature typically involved in a large number of spontaneous food fermentation. The purpose of this study was to characterize the bacteriocinogenic lactobacilli from fermented idli batter which can find application in biopreservation and biomedicine. Eight most promising lactobacilli were chosen from twenty two isolates based on their spectrum of activity against other lactic acid bacteria and pathogens. The eight lactobacilli were characterized based on the various classical phenotypic tests, physiological tests and biochemical tests including various carbohydrate utilization profiles. All isolates were homo fermentative, catalase, and gelatin negative. Molecular characterization was performed by RAPD, 16S rRNA analysis, 16S ARDRA, and Multiplex PCR for species identification. RAPD was carried out using the primer R2 and M13. Five different clusters were obtained based on RAPD indicating strain level variation. 16S rRNA analysis showed 99 to 100% homology towards Lactobacillus plantarum. The restriction digestion pattern was similar for all the isolates with the restriction enzyme AluI. The subspecies were identified by performing Multiplex PCR using species specific primer. Among the five clusters, three clusters were clearly identified as Lactobacillus plantarum subsp. plantarum, Lactobacillus pentosus, and Lactobacillus plantarum subsp. argentoratensis.

  14. Conventional Chiralpak ID vs. capillary Chiralpak ID-3 amylose tris-(3-chlorophenylcarbamate)-based chiral stationary phase columns for the enantioselective HPLC separation of pharmaceutical racemates.

    PubMed

    Ahmed, Marwa; Gwairgi, Marina; Ghanem, Ashraf

    2014-11-01

    A comparative enantioselective analysis using immobilized amylose tris-(3-chlorophenylcarbamate) as chiral stationary phase in conventional high-performance liquid chromatography (HPLC) with Chiralpak ID (4.6 mm ID × 250 mm, 5 µm silica gel) and micro-HPLC with Chiralpak ID-3 (0.30 mm ID × 150 mm, 3 µm silica gel) was conducted. Pharmaceutical racemates of 12 pharmacological classes, namely, α- and β-blockers, anti-inflammatory drugs, antifungal drugs, dopamine antagonists, norepinephrine-dopamine reuptake inhibitors, catecholamines, sedative hypnotics, diuretics, antihistaminics, anticancer drugs, and antiarrhythmic drugs were screened under normal phase conditions. The effect of an organic modifier on the analyte retentions and enantiomer recognition was investigated. Baseline separation was achieved for 1-acenaphthenol, carprofen, celiprolol, cizolirtine carbinol, miconazole, tebuconazole, 4-hydroxy-3-methoxymandelic acid, 1-indanol, 1-(2-chlorophenyl)ethanol, 1-phenyl-2-propanol, flavanone, 6-hydroxyflavanone, 4-bromogluthethimide, and pentobarbital on the 4.6 mm ID packed with a 5 µm silica column using conventional HPLC. Nonetheless, baseline separation was achieved for aminoglutethimide, naftopidil, and thalidomide on the 0.3 mm ID packed with a 3 µm silica capillary column.

  15. 34 CFR 84.645 - Federal agency or agency.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Federal agency or agency. 84.645 Section 84.645... WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 84.645 Federal agency or agency. Federal agency or agency.... 1082, 1094, 1221e-3 and 3474; and Sec. 2455, Pub. L. 103-355, 108 Stat. 3243 at 3327.)...

  16. 22 CFR 210.645 - Federal agency or agency.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Federal agency or agency. 210.645 Section 210.645 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 210.645 Federal agency or agency. Federal agency or...

  17. 22 CFR 210.645 - Federal agency or agency.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Federal agency or agency. 210.645 Section 210.645 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 210.645 Federal agency or agency. Federal agency or...

  18. 22 CFR 312.645 - Federal agency or agency.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Federal agency or agency. 312.645 Section 312.645 Foreign Relations PEACE CORPS GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 312.645 Federal agency or agency. Federal agency or agency means any United...

  19. 22 CFR 312.645 - Federal agency or agency.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Federal agency or agency. 312.645 Section 312.645 Foreign Relations PEACE CORPS GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 312.645 Federal agency or agency. Federal agency or agency means any United...

  20. 22 CFR 312.645 - Federal agency or agency.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Federal agency or agency. 312.645 Section 312.645 Foreign Relations PEACE CORPS GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 312.645 Federal agency or agency. Federal agency or agency means any United...

  1. High-speed readout method of ID information on a large amount of electronic tags

    NASA Astrophysics Data System (ADS)

    Nagate, Wataru; Sasabe, Masahiro; Nakano, Hirotaka

    2006-10-01

    An electronic tag such as RFID is expected to create new services that cannot be achieved by the traditional bar code. Specifically, in a distribution system, simultaneous readout method of a large amount of electronic tags embedded in products is required to reduce costs and time. In this paper, we propose novel methods, called Response Probability Control (RPC), to accomplish this requirement. In RPC, a reader firstly sends an ID request to electronic tags in its access area. It succeeds reading information on a tag only if other tags do not respond. To improve the readout efficiency, the reader appropriately controls the response probability in accordance with the number of tags. However, this approach cannot entirely avoid a collision of multiple responses. When a collision occurs, ID information is lost. To reduce the amount of lost data, we divide the ID registration process into two steps. The reader first gathers the former part of the original ID, called temporal ID, according to the above method. After obtaining the temporal ID, it sequentially collects the latter part of ID, called remaining ID, based on the temporal ID. Note that we determine the number of bits of a temporal ID in accordance with the number of tags in the access area so that each tag can be distinguishable. Through simulation experiments, we evaluate RPC in terms of the readout efficiency. Simulation results show that RPC can accomplish the readout efficiency 1.17 times higher than the traditional method where there are a thousand of electronic tags whose IDs are 128 bits.

  2. Agency and intervention

    PubMed Central

    Roskies, Adina L.

    2015-01-01

    Novel ways to intervene on brain function raise questions about agency and responsibility. Here, I discuss whether direct brain interventions, and in particular, deep brain stimulation, pose a threat to agency in individual cases, or to our general conceptualization of what it is to be a responsible agent. While I do not currently see evidence that these interventions constitute a global challenge to our concept of agency, they do have the potential to diminish agency in individuals. I consider whether the lack of evidence for a global challenge ratifies our folk conceptions, or is a necessary consequence of them. In closing, I propose that our theoretical understanding of agency and our therapeutic approaches could be improved with a more nuanced, multidimensional view of agency. PMID:26240430

  3. Documenting the Undocumented: A Review of the United States' First Municipal ID Program

    ERIC Educational Resources Information Center

    Lagunes, Paul F.; Levin, Brian M.; Ditlmann, Ruth K.

    2012-01-01

    The City of New Haven, CT, sought to promote the assimilation of its immigrants by becoming the first American city to provide a government-backed ID, the Elm City Resident Card, to all residents. This article tests the policy's effectiveness in commerce. We find that Hispanics/Latinos are asked to present an ID more than Whites/Anglos, showing…

  4. The helix-loop-helix Id-1 inhibits PSA expression in prostate cancer cells.

    PubMed

    Zielinski, Anne J; Fong, Sylvia; Allison, Juanita; Kawahara, Misako; Coppe, Jean-Philippe; Feiler, Heidi; Lee, Nancy M; Desprez, Pierre-Yves

    2010-05-15

    The inhibitor of basic helix-loop-helix transcription factors, Id-1, is an important gene whose expression increases during prostate cancer progression and that upregulates proliferation, migration and invasion. We used microarray analysis to identify the downstream genes whose transcriptional expression is modulated by Id-1 protein. We compared gene expression in control LNCaP cells and Id-1-transduced LNCaP cells, which become significantly more aggressive after Id-1 overexpression, thus mimicking the high levels of Id-1 detected in metastatic cell lines. We used the Affy HTA U133A Expression Arrays with 45,000 probe sets representing more than 39,000 transcripts. We found that one of the most significantly downregulated genes on Id-1 expression was kallikrein 3 [also called prostate specific antigen (PSA)], the most commonly used biomarker of prostate cancer. Here, we show that the reduction in PSA mRNA and protein expression associated with high-grade prostate cancers, which generally express high levels of Id-1, could be the consequence of Id-1 overexpression.

  5. Rethinking Social Network Assessment for Students with Intellectual Disabilities (ID) in Postsecondary Education

    ERIC Educational Resources Information Center

    Eisenman, Laura T.; Farley-Ripple, Elizabeth; Culnane, Mary; Freedman, Brian

    2013-01-01

    Social networks of persons with intellectual disabilities (ID) have been characterized as smaller and less diverse than those of typical peers. Advocates have focused on strengthening those social networks by expanding circles of social support, protection, and friendship. As young adults with ID experience increasing levels of community…

  6. 13. TIP TOP MINE. WOODEN STRUCTURE VISIBLE IN ID31C12 ISIN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. TIP TOP MINE. WOODEN STRUCTURE VISIBLE IN ID-31-C-12 ISIN UPPER LEFT. ALSO VISIBLE ARE TWO VERTICALLY BURIED LOGS ASSOCIATED WITH CABLES, ONE OF WHICH IS VISIBLE IN LOWER RIGHT. CAMERA POINTED SOUTH. - Florida Mountain Mining Sites, Tip Top Mine, West face Florida Mountain, approximately 150 feet below summit, Silver City, Owyhee County, ID

  7. 78 FR 45478 - Proposed Establishment of Class E Airspace; Salmon, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-29

    .../Distance Measuring Equipment (VOR/DME) navigation aid, Salmon, ID, to facilitate vectoring of Instrument... route domestic airspace extending upward from 1,200 feet above the surface at the Salmon VOR/DME... controlled airspace at the Salmon VOR/ DME, Salmon, ID. This proposal will be subject to an...

  8. Development and Evaluation of LEGUME ID: A ToolBook Multimedia Module.

    ERIC Educational Resources Information Center

    Hannaway, David B.; And Others

    1992-01-01

    Describes the development and advantages of LEGUME ID, a multimedia module for agricultural education. LEGUME ID is an example of how teachers, given the opportunity through accessible computer software programs, can create powerful teaching tools. Summarized is a student response to the use of this teacher-produced software program. (MCO)

  9. 78 FR 25406 - Proposed Modification of Class E Airspace; Twin Falls, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... Federal Aviation Administration 14 CFR Part 71 Proposed Modification of Class E Airspace; Twin Falls, ID...: This action proposes to modify Class E airspace at Twin Falls Joslin Field-Magic Valley Regional Airport, Twin Falls, ID. Controlled airspace is necessary to accommodate aircraft using the...

  10. 76 FR 28306 - Amendment of Class D and Class E Airspace; Idaho Falls, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... Federal Aviation Administration 14 CFR Part 71 Amendment of Class D and Class E Airspace; Idaho Falls, ID... existing Class D and Class E airspace at Idaho Falls, ID, by changing the name of the airport to Idaho Falls Regional Airport, and adjusting the geographic coordinates of the airport. This action also...

  11. 78 FR 40382 - Modification of Class D and E Airspace; Twin Falls, ID

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-05

    ... Federal Aviation Administration 14 CFR Part 71 Modification of Class D and E Airspace; Twin Falls, ID... Class E airspace at Twin Falls Joslin Field-Magic Valley Regional Airport, Twin Falls, ID, to... areas, as well as corrects the airport name to Twin Falls Joslin Field-Magic Valley Regional...

  12. 39. CALCINER CELL PLANS. TOGETHER WITH HAER ID33C37 ILLUSTRATES COMPLEXITY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    39. CALCINER CELL PLANS. TOGETHER WITH HAER ID-33-C-37 ILLUSTRATES COMPLEXITY OF PIPING. INEEL DRAWING NUMBER 200-0633-00-287-106445. FLUOR NUMBER 5775-CPP-633-P-50 - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

  13. 40. CALCINER CELL SECTIONS. TOGETHER WITH HAER ID33C37 ILLUSTRATES COMPLEXITY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    40. CALCINER CELL SECTIONS. TOGETHER WITH HAER ID-33-C-37 ILLUSTRATES COMPLEXITY OF PIPING. INEEL DRAWING NUMBER 200-0633-00-287-106446. FLUOR NUMBER 5775-CPP-P-51. - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

  14. 81 FR 16198 - Deer Flat National Wildlife Refuge, Canyon, Payette, Owyhee, and Washington Counties, ID, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2016-03-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE INTERIOR Fish and Wildlife Service Deer Flat National Wildlife Refuge, Canyon, Payette, Owyhee, and Washington..., 1010 Dearborn St., Caldwell, ID 83605. Homedale Public Library, 125 W Owyhee Ave., Homedale, ID...

  15. IdsA is the major geranylgeranyl pyrophosphate synthase involved in carotenogenesis in Corynebacterium glutamicum.

    PubMed

    Heider, Sabine A E; Peters-Wendisch, Petra; Beekwilder, Jules; Wendisch, Volker F

    2014-11-01

    Corynebacterium glutamicum, a yellow-pigmented soil bacterium that synthesizes the rare cyclic C50 carotenoid decaprenoxanthin and its glucosides, has been engineered for the production of various carotenoids. CrtE was assumed to be the major geranylgeranyl pyrophosphate (GGPP) synthase in carotenogenesis; however, deletion of crtE did not abrogate carotenoid synthesis. In silico analysis of the repertoire of prenyltransferases encoded by the C. glutamicum genome revealed two candidate GGPPS genes (idsA and ispB). The absence of pigmentation of an idsA deletion mutant and complementation experiments with a double deletion mutant lacking both idsA and crtE showed that IdsA is the major GGPPS of C. glutamicum and that crtE overexpression compensated for the lack of IdsA, whereas plasmid-borne overexpression of ispB did not. Purified His-tagged CrtE was active as a homodimer, whereas the active form of IdsA was homotetrameric. Both enzymes catalyzed prenyl transfer with isopentenyl pyrophosphate (IPP), dimethylallyl pyrophosphate, geranyl pyrophosphate and farnesylphosphate (FPP) as substrates. IdsA showed the highest catalytic efficiency with dimethylallyl pyrophosphate and IPP, whereas the catalytic efficiency of CrtE was highest with geranyl pyrophosphate and IPP. Finally, application of prenyltransferase overexpression revealed that combined overexpression of idsA and the IPP isomerase gene idi in the absence of crtE led to the highest decaprenoxanthin titer reported to date.

  16. The Numbers Game: Phasing in Generated ID Numbers at the University of Oregon

    ERIC Educational Resources Information Center

    Eveland, Sue

    2005-01-01

    With all the recent headlines about security breaches and information loss at financial and educational institutions, the higher education community needs to address the issue of using social security numbers as ID numbers. The University of Oregon undertook a change process to assign generated ID numbers to all records in their information…

  17. Ubiquitin-SUMO circuitry controls activated fanconi anemia ID complex dosage in response to DNA damage.

    PubMed

    Gibbs-Seymour, Ian; Oka, Yasuyoshi; Rajendra, Eeson; Weinert, Brian T; Passmore, Lori A; Patel, Ketan J; Olsen, Jesper V; Choudhary, Chunaram; Bekker-Jensen, Simon; Mailand, Niels

    2015-01-08

    We show that central components of the Fanconi anemia (FA) DNA repair pathway, the tumor suppressor proteins FANCI and FANCD2 (the ID complex), are SUMOylated in response to replication fork stalling. The ID complex is SUMOylated in a manner that depends on the ATR kinase, the FA ubiquitin ligase core complex, and the SUMO E3 ligases PIAS1/PIAS4 and is antagonized by the SUMO protease SENP6. SUMOylation of the ID complex drives substrate selectivity by triggering its polyubiquitylation by the SUMO-targeted ubiquitin ligase RNF4 to promote its removal from sites of DNA damage via the DVC1-p97 ubiquitin segregase complex. Deregulation of ID complex SUMOylation compromises cell survival following replication stress. Our results uncover a regulatory role for SUMOylation in the FA pathway, and we propose that ubiquitin-SUMO signaling circuitry is a mechanism that contributes to the balance of activated ID complex dosage at sites of DNA damage.

  18. Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells.

    PubMed

    McAllister, Sean D; Christian, Rigel T; Horowitz, Maxx P; Garcia, Amaia; Desprez, Pierre-Yves

    2007-11-01

    Invasion and metastasis of aggressive breast cancer cells is the final and fatal step during cancer progression, and is the least understood genetically. Clinically, there are still limited therapeutic interventions for aggressive and metastatic breast cancers available. Clearly, effective and nontoxic therapies are urgently required. Id-1, an inhibitor of basic helix-loop-helix transcription factors, has recently been shown to be a key regulator of the metastatic potential of breast and additional cancers. Using a mouse model, we previously determined that metastatic breast cancer cells became significantly less invasive in vitro and less metastatic in vivo when Id-1 was down-regulated by stable transduction with antisense Id-1. It is not possible at this point, however, to use antisense technology to reduce Id-1 expression in patients with metastatic breast cancer. Here, we report that cannabidiol (CBD), a cannabinoid with a low-toxicity profile, could down-regulate Id-1 expression in aggressive human breast cancer cells. The CBD concentrations effective at inhibiting Id-1 expression correlated with those used to inhibit the proliferative and invasive phenotype of breast cancer cells. CBD was able to inhibit Id-1 expression at the mRNA and protein level in a concentration-dependent fashion. These effects seemed to occur as the result of an inhibition of the Id-1 gene at the promoter level. Importantly, CBD did not inhibit invasiveness in cells that ectopically expressed Id-1. In conclusion, CBD represents the first nontoxic exogenous agent that can significantly decrease Id-1 expression in metastatic breast cancer cells leading to the down-regulation of tumor aggressiveness.

  19. Improving HybrID: How to best combine indirect and direct encoding in evolutionary algorithms

    PubMed Central

    Helms, Lucas; Clune, Jeff

    2017-01-01

    Many challenging engineering problems are regular, meaning solutions to one part of a problem can be reused to solve other parts. Evolutionary algorithms with indirect encoding perform better on regular problems because they reuse genomic information to create regular phenotypes. However, on problems that are mostly regular, but contain some irregularities, which describes most real-world problems, indirect encodings struggle to handle the irregularities, hurting performance. Direct encodings are better at producing irregular phenotypes, but cannot exploit regularity. An algorithm called HybrID combines the best of both: it first evolves with indirect encoding to exploit problem regularity, then switches to direct encoding to handle problem irregularity. While HybrID has been shown to outperform both indirect and direct encoding, its initial implementation required the manual specification of when to switch from indirect to direct encoding. In this paper, we test two new methods to improve HybrID by eliminating the need to manually specify this parameter. Auto-Switch-HybrID automatically switches from indirect to direct encoding when fitness stagnates. Offset-HybrID simultaneously evolves an indirect encoding with directly encoded offsets, eliminating the need to switch. We compare the original HybrID to these alternatives on three different problems with adjustable regularity. The results show that both Auto-Switch-HybrID and Offset-HybrID outperform the original HybrID on different types of problems, and thus offer more tools for researchers to solve challenging problems. The Offset-HybrID algorithm is particularly interesting because it suggests a path forward for automatically and simultaneously combining the best traits of indirect and direct encoding. PMID:28334002

  20. Negotiating with Subscription Agencies.

    ERIC Educational Resources Information Center

    McQueen, Judy; Basch, N. Bernard

    1991-01-01

    This first in a two-part series on how librarians can negotiate services and prices with subscription agencies focuses on how vendors operate. Factors that influence agency costs, revenues, and service charges are described, including economies of scale, discounts from publishers, and prepayment and cash flow. (seven references) (LRW)

  1. Improving global flood risk awareness through collaborative research: Id-Lab

    NASA Astrophysics Data System (ADS)

    Weerts, A.; Zijderveld, A.; Cumiskey, L.; Buckman, L.; Verlaan, M.; Baart, F.

    2015-12-01

    Scientific and end-user collaboration on operational flood risk modelling and forecasting requires an environment where scientists and end-users can physically work together and demonstrate, enhance and learn about new tools, methods and models for forecasting and warning purposes. Therefore, Deltares has built a real-time demonstration, training and research infrastructure ('operational' room and ICT backend). This research infrastructure supports various functions like (1) Real time response and disaster management, (2) Training, (3) Collaborative Research, (4) Demonstration. The research infrastructure will be used for a mixture of these functions on a regular basis by Deltares and a multitude of both scientists as well as end users such as universities, research institutes, consultants, governments and aid agencies. This infrastructure facilitates emergency advice and support during international and national disasters caused by rainfall, tropical cyclones or tsunamis. It hosts research flood and storm surge forecasting systems for global/continental/regional scale. It facilitates training for emergency & disaster management (along with hosting forecasting system user trainings in for instance the forecasting platform Delft-FEWS) both internally and externally. The facility is expected to inspire and initiate creative innovations by bringing together different experts from various organizations. The room hosts interactive modelling developments, participatory workshops and stakeholder meetings. State of the art tools, models and software, being applied across the globe are available and on display within the facility. We will present the Id-Lab in detail and we will put particular focus on the global operational forecasting systems GLOFFIS (Global Flood Forecasting Information System) and GLOSSIS (Global Storm Surge Information System).

  2. 22 CFR 1509.645 - Federal agency or agency.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Federal agency or agency. 1509.645 Section 1509.645 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1509.645 Federal agency or agency. Federal agency or...

  3. 22 CFR 1509.645 - Federal agency or agency.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Federal agency or agency. 1509.645 Section 1509.645 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1509.645 Federal agency or agency. Federal agency or...

  4. 22 CFR 1509.645 - Federal agency or agency.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Federal agency or agency. 1509.645 Section 1509.645 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1509.645 Federal agency or agency. Federal agency or...

  5. 22 CFR 1509.645 - Federal agency or agency.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Federal agency or agency. 1509.645 Section 1509.645 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1509.645 Federal agency or agency. Federal agency or...

  6. 22 CFR 1509.645 - Federal agency or agency.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Federal agency or agency. 1509.645 Section 1509.645 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1509.645 Federal agency or agency. Federal agency or...

  7. 28 CFR 83.645 - Federal agency or agency.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Federal agency or agency. 83.645 Section 83.645 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GOVERNMENT-WIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) Definitions § 83.645 Federal agency or agency. Federal agency or...

  8. Bio-fortification and shelf-life extension of idli batter using curry leaves (Murraya koenigii).

    PubMed

    Chelliah, R; Ramakrishnan, S R; Premkumar, D; Antony, U

    2016-06-01

    Among several traditional foods of India, idli is one of the most popular and commonly consumed steamed products. A new method of adding Murraya koenigii (curry leaves) to idli batter as a vehicle for fortification and extension of shelf-life has been developed. Dried curry leaves powder was incorporated with other ingredients like rice and dehusked black gram in different proportions to optimize the most palatable formulation. Rate of fermentation and microbial changes in the batter; nutritional qualities, texture and sensory properties of the prepared product were assessed. Incorporation of curry leaves powder (5 %) in idli batter increased the shelf-life and also increased the flavour, texture and appearance of the idli. The calcium content of the prepared idli was 10 times more than that of the control idli, while dietary fiber content increased by 18.6 %. Anti-microbial activity of the curry leaves in idli batter extended the shelf-life from 2 to 5 days when stored at 30 °C.

  9. SpDamID: Marking DNA Bound by Protein Complexes Identifies Notch-Dimer Responsive Enhancers.

    PubMed

    Hass, Matthew R; Liow, Hien-Haw; Chen, Xiaoting; Sharma, Ankur; Inoue, Yukiko U; Inoue, Takayoshi; Reeb, Ashley; Martens, Andrew; Fulbright, Mary; Raju, Saravanan; Stevens, Michael; Boyle, Scott; Park, Joo-Seop; Weirauch, Matthew T; Brent, Michael R; Kopan, Raphael

    2015-08-20

    We developed Split DamID (SpDamID), a protein complementation version of DamID, to mark genomic DNA bound in vivo by interacting or juxtapositioned transcription factors. Inactive halves of DAM (DNA adenine methyltransferase) were fused to protein pairs to be queried. Either direct interaction between proteins or proximity enabled DAM reconstitution and methylation of adenine in GATC. Inducible SpDamID was used to analyze Notch-mediated transcriptional activation. We demonstrate that Notch complexes label RBP sites broadly across the genome and show that a subset of these complexes that recruit MAML and p300 undergo changes in chromatin accessibility in response to Notch signaling. SpDamID differentiates between monomeric and dimeric binding, thereby allowing for identification of half-site motifs used by Notch dimers. Motif enrichment of Notch enhancers coupled with SpDamID reveals co-targeting of regulatory sequences by Notch and Runx1. SpDamID represents a sensitive and powerful tool that enables dynamic analysis of combinatorial protein-DNA transactions at a genome-wide level.

  10. The ID23-2 structural biology microfocus beamline at the ESRF

    PubMed Central

    Flot, David; Mairs, Trevor; Giraud, Thierry; Guijarro, Matias; Lesourd, Marc; Rey, Vicente; van Brussel, Denis; Morawe, Christian; Borel, Christine; Hignette, Olivier; Chavanne, Joel; Nurizzo, Didier; McSweeney, Sean; Mitchell, Edward

    2010-01-01

    The first phase of the ESRF beamline ID23 to be constructed was ID23-1, a tunable MAD-capable beamline which opened to users in early 2004. The second phase of the beamline to be constructed is ID23-2, a monochromatic microfocus beamline dedicated to macromolecular crystallography experiments. Beamline ID23-2 makes use of well characterized optical elements: a single-bounce silicon (111) monochromator and two mirrors in Kirkpatrick–Baez geometry to focus the X-ray beam. A major design goal of the ID23-2 beamline is to provide a reliable, easy-to-use and routine microfocus beam. ID23-2 started operation in November 2005, as the first beamline dedicated to microfocus macromolecular crystallography. The beamline has taken the standard automated ESRF macromolecular crystallography environment (both hardware and software), allowing users of ID23-2 to be rapidly familiar with the microfocus environment. This paper describes the beamline design, the special considerations taken into account given the microfocus beam, and summarizes the results of the first years of the beamline operation. PMID:20029119

  11. Tumor necrosis factor-alpha regulation of the Id gene family in astrocytes and microglia during CNS inflammatory injury.

    PubMed

    Tzeng, S F; Kahn, M; Liva, S; De Vellis, J

    1999-04-01

    The inhibitors of DNA binding (Id) gene family is highly expressed during embryogenesis and throughout adulthood in the rat central nervous system (CNS). In vitro studies suggest that the Id gene family is involved in the regulation of cell proliferation and differentiation. Recently, Id gene expression was shown to be expressed in immature and mature astrocytes during development and upregulated in reactive astrocytes after spinal cord injury. These results suggest that the Id gene family may play an important role in regulating astrocyte development and reactivity; however, the factors regulating Id expression in astrocytes remain undefined. Tumor necrosis factor-alpha (TNF alpha), a proinflammatory cytokine, is thought to play a crucial role in astrocyte/microglia activation after injury to the CNS. To determine if TNF alpha plays a role in Id gene expression, we exogenously administered TNF alpha into developing postnatal rats. We report that TNF alpha injections resulted in a rapid and transient increase in both cell number and mRNA expression for Id2 and Id3 when compared to levels observed in noninjected or control-injected animals. Id1 mRNA levels were also upregulated after TNF alpha treatment, but to a lesser degree. Significant increases in TNF alpha-induced Id2 and Id3 mRNA were observed in the ventricular/subventricular zone, cingulum and corpus callosum. TNF alpha also increased Id2 mRNA expression in the caudate putamen and hippocampus at the injection site. Id2 and Id3 mRNA+ cells were identified as GFAP+ and S100 alpha + astrocytes as well as ED1+ microglia. This is the first report to show TNF-alpha-induced modulation of the Id gene family and suggests that Id may be involved in the formation of reactive astrocytes and activated microglia in the rodent brain. These results suggest a putative role for the Id family in the molecular mechanisms regulating cellular responsiveness to TNF alpha and CNS inflammation.

  12. The Self-Identity Protein IdsD Is Communicated between Cells in Swarming Proteus mirabilis Colonies.

    PubMed

    Saak, Christina C; Gibbs, Karine A

    2016-12-15

    Proteus mirabilis is a social bacterium that is capable of self (kin) versus nonself recognition. Swarming colonies of this bacterium expand outward on surfaces to centimeter-scale distances due to the collective motility of individual cells. Colonies of genetically distinct populations remain separate, while those of identical populations merge. Ids proteins are essential for this recognition behavior. Two of these proteins, IdsD and IdsE, encode identity information for each strain. These two proteins bind in vitro in an allele-restrictive manner. IdsD-IdsE binding is correlated with the merging of populations, whereas a lack of binding is correlated with the separation of populations. Key questions remained about the in vivo interactions of IdsD and IdsE, specifically, whether IdsD and IdsE bind within single cells or whether IdsD-IdsE interactions occur across neighboring cells and, if so, which of the two proteins is exchanged. Here we demonstrate that IdsD must originate from another cell to communicate identity and that this nonresident IdsD interacts with IdsE resident in the recipient cell. Furthermore, we show that unbound IdsD in recipient cells does not cause cell death and instead appears to contribute to a restriction in the expansion radius of the swarming colony. We conclude that P. mirabilis communicates IdsD between neighboring cells for nonlethal kin recognition, which suggests that the Ids proteins constitute a type of cell-cell communication.

  13. Insulinotropic agent ID-1101 (4-hydroxyisoleucine) activates insulin signaling in rat.

    PubMed

    Broca, Christophe; Breil, Vincent; Cruciani-Guglielmacci, Céline; Manteghetti, Michèle; Rouault, Christine; Derouet, Michel; Rizkalla, Salwa; Pau, Bernard; Petit, Pierre; Ribes, Gérard; Ktorza, Alain; Gross, René; Reach, Gérard; Taouis, Mohammed

    2004-09-01

    ID-1101 (4-hydroxyisoleucine), an amino acid extracted from fenugreek seeds, exhibits an interesting glucose-dependent insulin-stimulating activity. The present study was undertaken to investigate a possible extrapancreatic effect of ID-1101 on insulin signaling and action besides its previously described insulinotropic action. Insulin-sensitizing effects of ID-1101 were investigated in rat in vivo by three different approaches: 1) using euglycemic hyperinsulinemic clamps in two different rat models of insulin resistance, i.e., Zucker fa/fa rats and rats fed a sucrose-lipid diet; 2) measuring liver and muscle phosphatidylinositol (PI) 3-kinase activity after an acute injection of ID-1101 in normal and insulin-resistant diabetic rats; and 3) after chronic treatment in two rat models of insulin resistance. Euglycemic hyperinsulinemic clamp experiments revealed that ID-1101 can improve insulin resistance through an increase of peripheral glucose utilization rate in sucrose-lipid-fed rats and by decreasing hepatic glucose production in Zucker fa/fa rats. Moreover, we demonstrated that a single injection of ID-1101 activates the PI 3-kinase activity in liver and muscle from normal rats but also in muscle from diabetic rats. Finally, chronic ID-1101 treatment significantly reduced insulinemia in type 2 diabetic rats and reduced the progression of hyperinsulinemia in insulin-resistant obese Zucker fa/fa rats. These findings clearly demonstrate that ID-1101 can reduce insulin resistance through activation of the early steps of insulin signaling in peripheral tissues and in liver. In summary, ID-1101, besides its insulinotropic effect, directly improves insulin sensitivity, making it a potentially very valuable therapeutic agent for diabetes treatment.

  14. Inactivation of ID4 promotes a CRPC phenotype with constitutive AR activation through FKBP52.

    PubMed

    Joshi, Jugal Bharat; Patel, Divya; Morton, Derrick J; Sharma, Pankaj; Zou, Jin; Hewa Bostanthirige, Dhanushka; Gorantla, Yamini; Nagappan, Peri; Komaragiri, Shravan Kumar; Sivils, Jeffrey C; Xie, Huan; Palaniappan, Ravi; Wang, Guangdi; Cox, Marc B; Chaudhary, Jaideep

    2016-11-27

    Castration-resistant prostate cancer (CRPC) is the emergence of prostate cancer cells that have adapted to the androgen-depleted environment of the prostate. In recent years, targeting multiple chaperones and co-chaperones (e.g., Hsp27, FKBP52) that promote androgen receptor (AR) signaling and/or novel AR regulatory mechanisms have emerged as promising alternative treatments for CRPC. We have shown that inactivation of inhibitor of differentiation 4 (ID4), a dominant-negative helix loop helix protein, promotes de novo steroidogenesis and CRPC with a gene expression signature that resembles constitutive AR activity in castrated mice. In this study, we investigated the underlying mechanism through which loss of ID4 potentiates AR signaling. Proteomic analysis between prostate cancer cell line LNCaP (L+ns) and LNCaP lacking ID4 (L(-)ID4) revealed elevated levels of Hsp27 and FKBP52, suggesting a role for these AR-associated co-chaperones in promoting constitutively active AR signaling in L(-)ID4 cells. Interestingly, protein interaction studies demonstrated a direct interaction between ID4 and the 52-kDa FK506-binding protein (FKBP52) in vitro, but not with AR. An increase in FKBP52-dependent AR transcriptional activity was observed in L(-)ID4 cells. Moreover, pharmacological inhibition of FKBP52-AR signaling, by treatment with MJC13, attenuated the tumor growth, weight, and volume in L(-)ID4 xenografts. Together, our results demonstrate that ID4 selectively regulates AR activity through direct interaction with FKBP52, and its loss, promotes CRPC through FKBP52-mediated AR signaling.

  15. Improvement and analysis of ID3 algorithm in decision-making tree

    NASA Astrophysics Data System (ADS)

    Xie, Xiao-Lan; Long, Zhen; Liao, Wen-Qi

    2015-12-01

    For the cooperative system under development, it needs to use the spatial analysis and relative technology concerning data mining in order to carry out the detection of the subject conflict and redundancy, while the ID3 algorithm is an important data mining. Due to the traditional ID3 algorithm in the decision-making tree towards the log part is rather complicated, this paper obtained a new computational formula of information gain through the optimization of algorithm of the log part. During the experiment contrast and theoretical analysis, it is found that IID3 (Improved ID3 Algorithm) algorithm owns higher calculation efficiency and accuracy and thus worth popularizing.

  16. Federal Emergency Management Agency

    MedlinePlus

    ... Updates Emergency Management Agencies Emergency Management Institute El Niño Environmental Planning and Historic Preservation Program Exercise Fact ... Local, State, Tribal and Non-Profit Recovery Resources Region I Region II Region III Region IV Region ...

  17. School Service Agency

    ERIC Educational Resources Information Center

    Leachen, Sylvia; Lipschitz, Beverly

    1970-01-01

    Describes school employment" agency to secure school jobs for interested students. They filled out applications, had interviews and secured recommendations. Program attempted to relieve hall congestion and improve tone of school. (Author/CJ)

  18. 77 FR 29615 - Privacy Act of 1974; System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    ... [Federal Register Volume 77, Number 97 (Friday, May 18, 2012)] [Notices] [Pages 29615-29616] [FR Doc No: 2012-12027] DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID DOD-2012-OS-0056] Privacy Act of 1974; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to amend...

  19. 75 FR 41368 - Public Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-16

    ... fees for search and review of agency records by NRC personnel. This document is necessary to inform the... to this final rule can be found at http://www.regulations.gov by searching on Docket ID NRC-2010-0157... Fees for search and review of agency records by NRC personnel. * * * * * (a) Clerical search and...

  20. 75 FR 81269 - Ward Transformer Superfund Site Raleigh, Wake County, NC; Notice of Settlements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-27

    ... AGENCY Ward Transformer Superfund Site Raleigh, Wake County, NC; Notice of Settlements AGENCY... Ward Transformer Superfund Site located in Raleigh, Wake County, North Carolina for publication. DATES... your comments, identified by Docket ID No. EPA-RO4- SFUND-2010-1053 or Site name Ward...