Science.gov

Sample records for agency specific requirements

  1. 45 CFR 205.58 - Income and eligibility information; specific agreements required between the State agency and the...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Income and eligibility information; specific agreements required between the State agency and the agency supplying the information. 205.58 Section 205.58 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND...

  2. TWRSview system requirements specification

    SciTech Connect

    Caldwell, J.A.; Lee, A.K.

    1995-12-01

    This document provides the system requirements specification for the TWRSview software system. The TWRSview software system is being developed to integrate electronic data supporting the development of the TWRS technical baseline

  3. ENVIROSAT-2000 report: Federal agency satellite requirements

    NASA Technical Reports Server (NTRS)

    Cotter, D. (Editor); Wolzer, I. (Editor); Blake, N.; Jarman, J.; Lichy, D.; Pangburn, T.; Mcardle, R.; Paul, C.; Shaffer, L.; Thorley, G.

    1985-01-01

    The requirement of Federal agencies, other than NOAA, for the data and services of civil operational environmental satellites (both polar orbiting and geostationary) are summarized. Agency plans for taking advantage of proposed future Earth sensing space systems, domestic and foreign, are cited also. Current data uses and future requirements are addressed as identified by each agency.

  4. Master Software Requirements Specification

    NASA Technical Reports Server (NTRS)

    Hu, Chaumin

    2003-01-01

    A basic function of a computational grid such as the NASA Information Power Grid (IPG) is to allow users to execute applications on remote computer systems. The Globus Resource Allocation Manager (GRAM) provides this functionality in the IPG and many other grids at this time. While the functionality provided by GRAM clients is adequate, GRAM does not support useful features such as staging several sets of files, running more than one executable in a single job submission, and maintaining historical information about execution operations. This specification is intended to provide the environmental and software functional requirements for the IPG Job Manager V2.0 being developed by AMTI for NASA.

  5. RMACS software requirements specification

    SciTech Connect

    Gneiting, B.C.

    1996-10-01

    This document defines the essential user (or functional) requirements of the Requirements Management and Assured Compliance System (RMACS), which is used by the Tank Waste Remediation System program (TWRS). RMACS provides a computer-based environment that TWRS management and systems engineers can use to identify, define, and document requirements. The intent of the system is to manage information supporting definition of the TWRS technical baseline using a structured systems engineering process. RMACS has the capability to effectively manage a complete set of complex requirements and relationships in a manner that satisfactorily assures compliance to the program requirements over the TWRS life-cycle.

  6. Requirements management system browser software requirements specification

    SciTech Connect

    Frank, D.D.

    1996-10-01

    The purpose of this document is to define the essential user requirements for the Requirements Management System Browser (RMSB) application. This includes specifications for the Graphical User Interface (GUI) and the supporting database structures. The RMSB application is needed to provide an easy to use PC-based interface to browse system engineering data stored and managed in a UNIX software application. The system engineering data include functions, requirements, and architectures that make up the Tank Waste Remediation System (TWRS) technical baseline. This document also covers the requirements for a software application titled ``RMSB Data Loader (RMSB- DL)``, referred to as the ``Parser.`` The Parser is needed to read and parse a data file and load the data structure supporting the Browser.

  7. 5 CFR 362.104 - Agency requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... identified in § 362.101 (e.g., OPM Internship Program); (2) State the delegations of authority for the agency... summer jobs; (6) Include a commitment from the agency to: (i) Provide to OPM any information it...

  8. 5 CFR 362.104 - Agency requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... identified in § 362.101 (e.g., OPM Internship Program); (2) State the delegations of authority for the agency... summer jobs; (6) Include a commitment from the agency to: (i) Provide to OPM any information it...

  9. 48 CFR 4.202 - Agency distribution requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Agency distribution... ADMINISTRATIVE MATTERS Contract Distribution 4.202 Agency distribution requirements. Agencies shall limit additional distribution requirements to the minimum necessary for proper performance of essential...

  10. 7 CFR 3560.753 - Agency appraisal standards and requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Agency appraisal standards and requirements. 3560.753... SERVICE, DEPARTMENT OF AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Appraisals § 3560.753 Agency appraisal standards and requirements. (a) General. The Agency recognizes USPAP as the...

  11. Validation of International Atomic Energy Agency Equipment Performance Requirements

    SciTech Connect

    Chiaro, PJ

    2004-02-17

    Performance requirements and testing protocols are needed to ensure that equipment used by the International Atomic Energy Agency (IAEA) is reliable. Oak Ridge National Laboratory (ORNL), through the US Support Program, tested equipment to validate performance requirements protocols used by the IAEA for the subject equipment categories. Performance protocol validation tests were performed in the Environmental Effects Laboratory in the categories for battery, DC power supply, and uninterruptible power supply (UPS). Specific test results for each piece of equipment used in the validation process are included in this report.

  12. Project X functional requirements specification

    SciTech Connect

    Holmes, S.D.; Henderson, S.D.; Kephart, R.; Kerby, J.; Kourbanis, I.; Lebedev, V.; Mishra, S.; Nagaitsev, S.; Solyak, N.; Tschirhart, R.; /Fermilab

    2012-05-01

    Project X is a multi-megawatt proton facility being developed to support a world-leading program in Intensity Frontier physics at Fermilab. The facility is designed to support programs in elementary particle and nuclear physics, with possible applications to nuclear energy research. A Functional Requirements Specification has been developed in order to establish performance criteria for the Project X complex in support of these multiple missions, and to assure that the facility is designed with sufficient upgrade capability to provide U.S. leadership for many decades to come. This paper will briefly review the previously described Functional Requirements, and then discuss their recent evolution.

  13. 42 CFR 441.16 - Home health agency requirements for surety bonds; Prohibition on FFP.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Home health agency requirements for surety bonds... OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS SERVICES: REQUIREMENTS AND LIMITS APPLICABLE TO SPECIFIC SERVICES General Provisions § 441.16 Home health agency requirements...

  14. 42 CFR 441.16 - Home health agency requirements for surety bonds; Prohibition on FFP.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Home health agency requirements for surety bonds... OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS SERVICES: REQUIREMENTS AND LIMITS APPLICABLE TO SPECIFIC SERVICES General Provisions § 441.16 Home health agency requirements...

  15. Flight Guidance System Requirements Specification

    NASA Technical Reports Server (NTRS)

    Miller, Steven P.; Tribble, Alan C.; Carlson, Timothy M.; Danielson, Eric J.

    2003-01-01

    This report describes a requirements specification written in the RSML-e language for the mode logic of a Flight Guidance System of a typical regional jet aircraft. This model was created as one of the first steps in a five-year project sponsored by the NASA Langley Research Center, Rockwell Collins Inc., and the Critical Systems Research Group of the University of Minnesota to develop new methods and tools to improve the safety of avionics designs. This model will be used to demonstrate the application of a variety of methods and techniques, including safety analysis of system and subsystem requirements, verification of key properties using theorem provers and model checkers, identification of potential sources mode confusion in system designs, partitioning of applications based on the criticality of system hazards, and autogeneration of avionics quality code. While this model is representative of the mode logic of a typical regional jet aircraft, it does not describe an actual or planned product. Several aspects of a full Flight Guidance System, such as recovery from failed sensors, have been omitted, and no claims are made regarding the accuracy or completeness of this specification.

  16. 40 CFR 35.6250 - Support agency Cooperative Agreement requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Support Agency Cooperative Agreements § 35.6250 Support agency... submit a non-site-specific budget for support agency activities. (b) Cooperative Agreement...

  17. 40 CFR 35.6250 - Support agency Cooperative Agreement requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Support Agency Cooperative Agreements § 35.6250 Support agency... submit a non-site-specific budget for support agency activities. (b) Cooperative Agreement...

  18. 40 CFR 35.6250 - Support agency Cooperative Agreement requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Support Agency Cooperative Agreements § 35.6250 Support agency... submit a non-site-specific budget for support agency activities. (b) Cooperative Agreement...

  19. 40 CFR 35.6250 - Support agency Cooperative Agreement requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Support Agency Cooperative Agreements § 35.6250 Support agency... submit a non-site-specific budget for support agency activities. (b) Cooperative Agreement...

  20. 40 CFR 35.6250 - Support agency Cooperative Agreement requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Support Agency Cooperative Agreements § 35.6250 Support agency... submit a non-site-specific budget for support agency activities. (b) Cooperative Agreement...

  1. 32 CFR 2001.90 - Agency annual reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Agency annual reporting requirements. 2001.90... Reporting and Definitions § 2001.90 Agency annual reporting requirements. (a) Delegations of original... in accordance with section 1.3(c) of the Order and § 2001.11(c). (b) Statistical reporting....

  2. 32 CFR 2001.90 - Agency annual reporting requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 6 2012-07-01 2012-07-01 false Agency annual reporting requirements. 2001.90 Section 2001.90 National Defense Other Regulations Relating to National Defense INFORMATION SECURITY... Reporting and Definitions § 2001.90 Agency annual reporting requirements. (a) Delegations of...

  3. 32 CFR 2001.90 - Agency annual reporting requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false Agency annual reporting requirements. 2001.90 Section 2001.90 National Defense Other Regulations Relating to National Defense INFORMATION SECURITY... Reporting and Definitions § 2001.90 Agency annual reporting requirements. (a) Delegations of...

  4. 32 CFR 2001.91 - Other agency reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Other agency reporting requirements. 2001.91 Section 2001.91 National Defense Other Regulations Relating to National Defense INFORMATION SECURITY... Reporting and Definitions § 2001.91 Other agency reporting requirements. (a) Information...

  5. 32 CFR 2001.91 - Other agency reporting requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 6 2012-07-01 2012-07-01 false Other agency reporting requirements. 2001.91 Section 2001.91 National Defense Other Regulations Relating to National Defense INFORMATION SECURITY... Reporting and Definitions § 2001.91 Other agency reporting requirements. (a) Information...

  6. 32 CFR 2001.91 - Other agency reporting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 6 2014-07-01 2014-07-01 false Other agency reporting requirements. 2001.91 Section 2001.91 National Defense Other Regulations Relating to National Defense INFORMATION SECURITY... Reporting and Definitions § 2001.91 Other agency reporting requirements. (a) Information...

  7. 32 CFR 2001.90 - Agency annual reporting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 6 2014-07-01 2014-07-01 false Agency annual reporting requirements. 2001.90 Section 2001.90 National Defense Other Regulations Relating to National Defense INFORMATION SECURITY... Reporting and Definitions § 2001.90 Agency annual reporting requirements. (a) Delegations of...

  8. 32 CFR 2001.90 - Agency annual reporting requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false Agency annual reporting requirements. 2001.90 Section 2001.90 National Defense Other Regulations Relating to National Defense INFORMATION SECURITY... Reporting and Definitions § 2001.90 Agency annual reporting requirements. (a) Delegations of...

  9. 2 CFR 25.215 - Requirements for agency information systems.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Requirements for agency information systems... information related to the awards, and other systems as appropriate, are able to accept and use the DUNS... UNIVERSAL IDENTIFIER AND CENTRAL CONTRACTOR REGISTRATION Policy § 25.215 Requirements for agency...

  10. 22 CFR 226.49 - USAID-Specific procurement requirements

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false USAID-Specific procurement requirements 226.49 Section 226.49 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ADMINISTRATION OF ASSISTANCE AWARDS TO U.S. NON-GOVERNMENTAL ORGANIZATIONS Post-award Requirements Procurement Standards § 226.49...

  11. 22 CFR 226.49 - USAID-Specific procurement requirements

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false USAID-Specific procurement requirements 226.49 Section 226.49 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ADMINISTRATION OF ASSISTANCE AWARDS TO U.S. NON-GOVERNMENTAL ORGANIZATIONS Post-award Requirements Procurement Standards § 226.49...

  12. 22 CFR 226.49 - USAID-Specific procurement requirements

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false USAID-Specific procurement requirements 226.49 Section 226.49 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ADMINISTRATION OF ASSISTANCE AWARDS TO U.S. NON-GOVERNMENTAL ORGANIZATIONS Post-award Requirements Procurement Standards § 226.49...

  13. 22 CFR 226.49 - USAID-Specific procurement requirements

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false USAID-Specific procurement requirements 226.49 Section 226.49 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ADMINISTRATION OF ASSISTANCE AWARDS TO U.S. NON-GOVERNMENTAL ORGANIZATIONS Post-award Requirements Procurement Standards § 226.49...

  14. 22 CFR 226.49 - USAID-Specific procurement requirements

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false USAID-Specific procurement requirements 226.49 Section 226.49 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ADMINISTRATION OF ASSISTANCE AWARDS TO U.S. NON-GOVERNMENTAL ORGANIZATIONS Post-award Requirements Procurement Standards § 226.49...

  15. 36 CFR 297.4 - Requirements for Federal agencies.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... WILD AND SCENIC RIVERS Water Resources Projects § 297.4 Requirements for Federal agencies. (a) No license, permit, or other authorization can be issued for a Federally assisted water resources project on... of proposed action, the Federal agency shall provide a notice of intent to issue such license,...

  16. 19 CFR 134.31 - Requirements of other agencies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Requirements of other agencies. 134.31 Section 134.31 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF... those of the Federal Trade Commission, Food and Drug Administration, and other agencies....

  17. 36 CFR 297.4 - Requirements for Federal agencies.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... WILD AND SCENIC RIVERS Water Resources Projects § 297.4 Requirements for Federal agencies. (a) No license, permit, or other authorization can be issued for a Federally assisted water resources project on... of proposed action, the Federal agency shall provide a notice of intent to issue such license,...

  18. 2 CFR 25.215 - Requirements for agency information systems.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Requirements for agency information systems... information systems. Each agency that makes awards (as defined in § 25.325) must ensure that systems processing information related to the awards, and other systems as appropriate, are able to accept and...

  19. 2 CFR 25.215 - Requirements for agency information systems.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Requirements for agency information systems... information systems. Each agency that makes awards (as defined in § 25.325) must ensure that systems processing information related to the awards, and other systems as appropriate, are able to accept and...

  20. 40 CFR 86.1406 - Equipment required and specifications; overview.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 19 2011-07-01 2011-07-01 false Equipment required and specifications; overview. 86.1406 Section 86.1406 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... specifications; overview. (a) Exhaust emission tests. All vehicles subject to this subpart are tested for...

  1. 36 CFR 1222.30 - When must agencies comply with the recordkeeping requirements of other agencies?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false When must agencies comply with the recordkeeping requirements of other agencies? 1222.30 Section 1222.30 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND...

  2. 36 CFR 1222.30 - When must agencies comply with the recordkeeping requirements of other agencies?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false When must agencies comply with the recordkeeping requirements of other agencies? 1222.30 Section 1222.30 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND...

  3. 36 CFR 1222.30 - When must agencies comply with the recordkeeping requirements of other agencies?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true When must agencies comply with the recordkeeping requirements of other agencies? 1222.30 Section 1222.30 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE...

  4. 36 CFR 1222.30 - When must agencies comply with the recordkeeping requirements of other agencies?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false When must agencies comply with the recordkeeping requirements of other agencies? 1222.30 Section 1222.30 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND...

  5. 36 CFR 1222.30 - When must agencies comply with the recordkeeping requirements of other agencies?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false When must agencies comply with the recordkeeping requirements of other agencies? 1222.30 Section 1222.30 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND...

  6. 19 CFR 134.31 - Requirements of other agencies.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Requirements of other agencies. 134.31 Section 134.31 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY COUNTRY OF ORIGIN MARKING Exceptions to Marking Requirements § 134.31 Requirements...

  7. 41 CFR 102-75.985 - Is the landholding agency required to assist the disposal agency in the disposition process?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... agency required to assist the disposal agency in the disposition process? 102-75.985 Section 102-75.985... disposal agency in the disposition process? Yes, the landholding agency must cooperate with the disposal... are incurred in showing the property, the landholding agency must absorb the entire cost of...

  8. 40 CFR 35.3135 - Specific capitalization grant agreement requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Specific capitalization grant agreement requirements. 35.3135 Section 35.3135 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE State Water Pollution Control Revolving Funds §...

  9. 40 CFR 35.3135 - Specific capitalization grant agreement requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Specific capitalization grant agreement requirements. 35.3135 Section 35.3135 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE State Water Pollution Control Revolving Funds §...

  10. 40 CFR 35.3135 - Specific capitalization grant agreement requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Specific capitalization grant agreement requirements. 35.3135 Section 35.3135 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE State Water Pollution Control Revolving Funds §...

  11. 40 CFR 35.3135 - Specific capitalization grant agreement requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Specific capitalization grant agreement requirements. 35.3135 Section 35.3135 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE State Water Pollution Control Revolving Funds §...

  12. 40 CFR 35.3135 - Specific capitalization grant agreement requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Specific capitalization grant agreement requirements. 35.3135 Section 35.3135 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE State Water Pollution Control Revolving Funds §...

  13. 14 CFR 145.5 - Certificate and operations specifications requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Certificate and operations specifications requirements. 145.5 Section 145.5 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SCHOOLS AND OTHER CERTIFICATED AGENCIES REPAIR STATIONS General § 145.5...

  14. 2 CFR 25.215 - Requirements for agency information systems.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Requirements for agency information systems. 25.215 Section 25.215 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET GOVERNMENTWIDE GUIDANCE FOR GRANTS AND AGREEMENTS...

  15. 7 CFR 765.351 - Requirements to obtain Agency consent.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 765.351 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY... security is not diminished; (7) The environmental requirements of subpart G of 7 CFR part 1940 must be met..., gravel, oil, gas, coal, or other resources and the sale by unit or lump sum payment will be considered...

  16. 7 CFR 765.351 - Requirements to obtain Agency consent.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 765.351 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY... security is not diminished; (7) The environmental requirements of subpart G of 7 CFR part 1940 must be met... sale by unit or lump sum payment will be considered a disposition of security. (iii) For loans...

  17. 78 FR 58544 - Agency Recordkeeping/Reporting Requirements Under Emergency

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-24

    ... HUMAN SERVICES Administration for Children and Families Agency Recordkeeping/Reporting Requirements Under Emergency Review by the Office of Management and Budget (OMB) Title: OCSE-75 Tribal Child Support... accomplishments in an annual narrative report and submit the OCSE-75 report annually. Respondents: Tribal...

  18. Solid Waste Information and Tracking System (SWITS) Software Requirements Specification

    SciTech Connect

    MAY, D.L.

    2000-03-22

    This document is the primary document establishing requirements for the Solid Waste Information and Tracking System (SWITS) as it is converted to a client-server architecture. The purpose is to provide the customer and the performing organizations with the requirements for the SWITS in the new environment. This Software Requirement Specification (SRS) describes the system requirements for the SWITS Project, and follows the PHMC Engineering Requirements, HNF-PRO-1819, and Computer Software Qualify Assurance Requirements, HNF-PRO-309, policies. This SRS includes sections on general description, specific requirements, references, appendices, and index. The SWITS system defined in this document stores information about the solid waste inventory on the Hanford site. Waste is tracked as it is generated, analyzed, shipped, stored, and treated. In addition to inventory reports a number of reports for regulatory agencies are produced.

  19. Requirements Specification Language (RSL) and supporting tools

    NASA Technical Reports Server (NTRS)

    Frincke, Deborah; Wolber, Dave; Fisher, Gene; Cohen, Gerald C.

    1992-01-01

    This document describes a general purpose Requirement Specification Language (RSL). RSL is a hybrid of features found in several popular requirement specification languages. The purpose of RSL is to describe precisely the external structure of a system comprised of hardware, software, and human processing elements. To overcome the deficiencies of informal specification languages, RSL includes facilities for mathematical specification. Two RSL interface tools are described. The Browser view contains a complete document with all details of the objects and operations. The Dataflow view is a specialized, operation-centered depiction of a specification that shows how specified operations relate in terms of inputs and outputs.

  20. Structured representation for requirements and specifications

    NASA Technical Reports Server (NTRS)

    Cohen, Gerald C.; Fisher, Gene; Frincke, Deborah; Wolber, Dave

    1991-01-01

    This document was generated in support of NASA contract NAS1-18586, Design and Validation of Digital Flight Control Systems suitable for Fly-By-Wire Applications, Task Assignment 2. Task 2 is associated with a formal representation of requirements and specifications. In particular, this document contains results associated with the development of a Wide-Spectrum Requirements Specification Language (WSRSL) that can be used to express system requirements and specifications in both stylized and formal forms. Included with this development are prototype tools to support the specification language. In addition a preliminary requirements specification methodology based on the WSRSL has been developed. Lastly, the methodology has been applied to an Advanced Subsonic Civil Transport Flight Control System.

  1. 30 CFR 20.7 - Specific requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP LAMPS § 20.7 Specific requirements. Two general classes of electric lamps are recognized in these requirements, namely: Class 1, those...-contained and not so readily portable as the first class. (a) Class 1. Class 1 includes hand lamps,...

  2. In Situ Vitrification software requirements specification

    SciTech Connect

    Grush, W.H.; Marwil, E.S.

    1990-09-01

    This report describes the Software Requirements Specification for the Electrical Resistance Heating and Thermal Energy Transport models of the In-Situ Vitrification (ISV) process. It contains the Data Flow Diagrams, Process Specifications, Data Structure Diagrams, and the Data Dictionary. 5 refs.

  3. Business System Planning Project System Requirements Specification

    SciTech Connect

    NELSON, R.E.

    2000-09-08

    The purpose of the Business Systems Planning Project System Requirements Specification (SRS) is to provide the outline and contents of the requirements for the CH2M HILL Hanford Group, Inc. (CHG) integrated business and technical information systems. The SRS will translate proposed objectives into the statement of the functions that are to be performed and data and information flows that they require. The requirements gathering methodology will use (1) facilitated group requirement sessions; (2) individual interviews; (3) surveys; and (4) document reviews. The requirements will be verified and validated through coordination of the technical requirement team and CHG Managers. The SRS document used the content and format specified in Lockheed Martin Services, Inc. Organization Standard Software Practices in conjunction with the Institute of Electrical and Electronics Engineers Standard 8340-1984 for Systems Requirements Documents.

  4. Improvements to Technical Specifications surveillance requirements

    SciTech Connect

    Lobel, R.; Tjader, T.R.

    1992-12-01

    In August 1983 an NRC task group was formed to investigate problems with surveillance testing required by Technical Specifications, and to recommend approaches to effect improvements. NUREG-1024 ( Technical Specifications-Enhancing Safety Impact'') resulted, and it contained recommendations to review the basis for test frequencies; to ensure that the tests promote safety and do not degrade equipment; and to review surveillance tests so that they do not unnecessarily burden personnel. The Technical Specifications Improvement Program (TSIP) was established in December 1984 to provide the framework for rewriting and improving the Technical Specifications. As an element of the TSIP, all Technical Specifications surveillance requirements were comprehensively examined as recommended in NUREG-1024. The results of that effort are presented in this report. The study found that while some testing at power is essential to verify equipment and system operability, safety can be improved, equipment degradation decreased, and unnecessary personnel burden relaxed by reducing the amount of testing at power.

  5. 20 CFR 411.395 - Is a State VR agency required to provide periodic reports?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Is a State VR agency required to provide... § 411.395 Is a State VR agency required to provide periodic reports? (a) For cases where a State VR agency provided services functioning as an EN, the State VR agency will be required to prepare...

  6. 20 CFR 411.395 - Is a State VR agency required to provide periodic reports?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Is a State VR agency required to provide... § 411.395 Is a State VR agency required to provide periodic reports? (a) For cases where a State VR agency provided services functioning as an EN, the State VR agency will be required to prepare...

  7. 30 CFR 22.7 - Specific requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... APPROVAL OF MINING PRODUCTS PORTABLE METHANE DETECTORS § 22.7 Specific requirements. (a) Design. In the... shall be of such design that it will not produce sparks that will ignite an explosive mixture of methane and air. (5) Detectors of the flame type. Methane detectors of the flame type shall be subject to...

  8. 30 CFR 22.7 - Specific requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... APPROVAL OF MINING PRODUCTS PORTABLE METHANE DETECTORS § 22.7 Specific requirements. (a) Design. In the... shall be of such design that it will not produce sparks that will ignite an explosive mixture of methane and air. (5) Detectors of the flame type. Methane detectors of the flame type shall be subject to...

  9. 40 CFR 166.32 - Reporting and recordkeeping requirements for specific, quarantine, and public health exemptions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... requirements for specific, quarantine, and public health exemptions. 166.32 Section 166.32 Protection of... AGENCIES FOR USE OF PESTICIDES UNDER EMERGENCY CONDITIONS Specific, Quarantine, and Public Health Exemptions § 166.32 Reporting and recordkeeping requirements for specific, quarantine, and public...

  10. 40 CFR 166.32 - Reporting and recordkeeping requirements for specific, quarantine, and public health exemptions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... requirements for specific, quarantine, and public health exemptions. 166.32 Section 166.32 Protection of... AGENCIES FOR USE OF PESTICIDES UNDER EMERGENCY CONDITIONS Specific, Quarantine, and Public Health Exemptions § 166.32 Reporting and recordkeeping requirements for specific, quarantine, and public...

  11. 40 CFR 166.32 - Reporting and recordkeeping requirements for specific, quarantine, and public health exemptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... requirements for specific, quarantine, and public health exemptions. 166.32 Section 166.32 Protection of... AGENCIES FOR USE OF PESTICIDES UNDER EMERGENCY CONDITIONS Specific, Quarantine, and Public Health Exemptions § 166.32 Reporting and recordkeeping requirements for specific, quarantine, and public...

  12. 40 CFR 166.32 - Reporting and recordkeeping requirements for specific, quarantine, and public health exemptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... requirements for specific, quarantine, and public health exemptions. 166.32 Section 166.32 Protection of... AGENCIES FOR USE OF PESTICIDES UNDER EMERGENCY CONDITIONS Specific, Quarantine, and Public Health Exemptions § 166.32 Reporting and recordkeeping requirements for specific, quarantine, and public...

  13. 40 CFR 166.32 - Reporting and recordkeeping requirements for specific, quarantine, and public health exemptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... requirements for specific, quarantine, and public health exemptions. 166.32 Section 166.32 Protection of... AGENCIES FOR USE OF PESTICIDES UNDER EMERGENCY CONDITIONS Specific, Quarantine, and Public Health Exemptions § 166.32 Reporting and recordkeeping requirements for specific, quarantine, and public...

  14. Complying with Agency Fee Requirements: A Practical Guide for Unions.

    ERIC Educational Resources Information Center

    Francke, Ann H.

    This guide to regulation of agency fees, the monies that unions collect from individuals in a bargaining unit who decline to join the union, discusses the rationale for the fees, outlines procedures for collecting them, and provides excerpts of representative agency fee provisions of existing contracts. The principle on which agency fees are based…

  15. 34 CFR 5.12 - Creation of agency records not required.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 1 2013-07-01 2013-07-01 false Creation of agency records not required. 5.12 Section 5.12 Education Office of the Secretary, Department of Education AVAILABILITY OF INFORMATION TO THE PUBLIC Agency Records Available to the Public § 5.12 Creation of agency records not required. In...

  16. 34 CFR 5.12 - Creation of agency records not required.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 1 2014-07-01 2014-07-01 false Creation of agency records not required. 5.12 Section 5.12 Education Office of the Secretary, Department of Education AVAILABILITY OF INFORMATION TO THE PUBLIC Agency Records Available to the Public § 5.12 Creation of agency records not required. In...

  17. 34 CFR 5.12 - Creation of agency records not required.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 1 2011-07-01 2011-07-01 false Creation of agency records not required. 5.12 Section 5.12 Education Office of the Secretary, Department of Education AVAILABILITY OF INFORMATION TO THE PUBLIC Agency Records Available to the Public § 5.12 Creation of agency records not required. In...

  18. 34 CFR 5.12 - Creation of agency records not required.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 1 2012-07-01 2012-07-01 false Creation of agency records not required. 5.12 Section 5.12 Education Office of the Secretary, Department of Education AVAILABILITY OF INFORMATION TO THE PUBLIC Agency Records Available to the Public § 5.12 Creation of agency records not required. In...

  19. 7 CFR 3406.6 - USDA agency cooperator requirement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... agency or office has agreed to cooperate with the applicant institution on the proposed project. The documentation should describe the expected benefits of the partnership venture for the USDA agency and for the 1890 Institution, and describe the partnership effort between USDA and the 1890 Institution in...

  20. 7 CFR 765.351 - Requirements to obtain Agency consent.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... repayment of the loan. (b) Sale of timber, gravel, oil, gas, coal, or other minerals. (1) Agency security... transactions, including, but not limited to, cutting, removal, or lease of timber, gravel, oil, gas, coal, or... the security. (ii) When the Agency has a security interest in oil, gas, or other minerals as...

  1. 7 CFR 3560.753 - Agency appraisal standards and requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... concluded by each approach. (f) Real estate history. Appraisals must contain a 5-year ownership and sales... estate, which is the land and improvements, and the real property, or property rights, being appraised...) Appraisers. MFH appraisals prepared for the Agency will be written by Agency appraisers or independent...

  2. 7 CFR 3560.753 - Agency appraisal standards and requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... concluded by each approach. (f) Real estate history. Appraisals must contain a 5-year ownership and sales... estate, which is the land and improvements, and the real property, or property rights, being appraised...) Appraisers. MFH appraisals prepared for the Agency will be written by Agency appraisers or independent...

  3. 77 FR 27539 - Reports, Forms, and Recordkeeping Requirements; Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-10

    ... instrumented motorcycles. The National Highway Traffic Safety Administration (NHTSA) will be conducting on-road... National Highway Traffic Safety Administration Reports, Forms, and Recordkeeping Requirements; Agency Information Collection Activity Under OMB Review AGENCY: National Highway Traffic Safety Administration...

  4. 75 FR 36637 - Agency Information Collection Activities; Proposed Collection; Comment Request; Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-28

    ... COMMISSION Agency Information Collection Activities; Proposed Collection; Comment Request; Requirements for... comment on the proposed collection of certain information by the agency. Under the Paperwork Reduction Act... concerning each proposed collection of information, including each proposed extension of an...

  5. 75 FR 36638 - Agency Information Collection Activities; Proposed Collection; Comment Request; Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-28

    ... COMMISSION Agency Information Collection Activities; Proposed Collection; Comment Request; Requirements for... the proposed collection of certain information by the agency. Under the Paperwork Reduction Act of... each proposed collection of information, including each proposed extension of an existing collection...

  6. 76 FR 66127 - Reports, Forms and Recordkeeping Requirements; Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-25

    ... Maritime Administration Reports, Forms and Recordkeeping Requirements; Agency Information Collection Activity Under OMB Review AGENCY: Maritime Administration, DOT. ACTION: Notice and request for comments... November 25, 2011. FOR FURTHER INFORMATION CONTACT: Dennis Brennan, Maritime Administration, 1200...

  7. 77 FR 26824 - Agency Information Collection; Activity Under OMB Review; Reporting Required for International...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-07

    ... Research & Innovative Technology Administration Agency Information Collection; Activity Under OMB Review; Reporting Required for International Civil Aviation Organization (ICAO) AGENCY: Research & Innovative..., Research and Innovative Technology Administration. BILLING CODE 4910-HY-P...

  8. 76 FR 24561 - Reports, Forms and Recordkeeping Requirements; Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-02

    ... Maritime Administration Reports, Forms and Recordkeeping Requirements; Agency Information Collection Activity Under OMB Review AGENCY: Maritime Administration, DOT. ACTION: Notice and request for comments... Administration (MARAD). Title: MARAD's Marine Transportation Economic Impact Model Data Needs. OMB Control...

  9. 7 CFR 764.453 - Agency waiver of training requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... writing. (b) The Agency will grant a waiver for training in production, financial management, or both... will consider the collective knowledge and skills of those individuals when determining whether...

  10. 7 CFR 764.453 - Agency waiver of training requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... writing. (b) The Agency will grant a waiver for training in production, financial management, or both... will consider the collective knowledge and skills of those individuals when determining whether...

  11. 42 CFR 488.68 - State Agency responsibilities for OASIS collection and data base requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 5 2012-10-01 2012-10-01 false State Agency responsibilities for OASIS collection..., CERTIFICATION, AND ENFORCEMENT PROCEDURES Special Requirements § 488.68 State Agency responsibilities for OASIS... operating the OASIS system: (a) Establish and maintain an OASIS database. The State agency or other...

  12. The Effect of Violations of the Constant Demand Assumption on the Defense Logistic Agency Requirements Model

    DTIC Science & Technology

    1994-09-01

    Defenae Logistica Agency The Defense Logistics Agency (DLA) is an agency of the Department of Defense. "The National Security Act (NSA) established...classification, requirements and supply control, procurement, quality and reliability assurance, industrial mobilization planning, storage, inventory...Operations Research Analyst, Defense Industrial Supply Center, Philadelphia PA. Telephone interview/Facsimile transmittal. May 1994 Chatterton, Brian

  13. 7 CFR 253.5 - State agency requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... discrimination in the certification of applicant households or in the distribution of commodities because of sex, race, color, age, political beliefs, religion, handicap or national origin. (v) Households shall not be... other sources. (g) Nutrition education. The State agency shall publicize how commodities may be used...

  14. 7 CFR 253.5 - State agency requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... discrimination in the certification of applicant households or in the distribution of commodities because of sex, race, color, age, political beliefs, religion, handicap or national origin. (v) Households shall not be... other sources. (g) Nutrition education. The State agency shall publicize how commodities may be used...

  15. 7 CFR 253.5 - State agency requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... discrimination in the certification of applicant households or in the distribution of commodities because of sex, race, color, age, political beliefs, religion, handicap or national origin. (v) Households shall not be... other sources. (g) Nutrition education. The State agency shall publicize how commodities may be used...

  16. 7 CFR 253.5 - State agency requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... discrimination in the certification of applicant households or in the distribution of commodities because of sex, race, color, age, political beliefs, religion, handicap or national origin. (v) Households shall not be... other sources. (g) Nutrition education. The State agency shall publicize how commodities may be used...

  17. 40 CFR 270.21 - Specific part B information requirements for landfills.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... requirements for landfills. 270.21 Section 270.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Permit Application § 270.21 Specific part B information requirements for landfills. Except as otherwise provided in § 264.1, owners and operators of facilities that dispose of hazardous waste in landfills...

  18. 40 CFR 270.21 - Specific part B information requirements for landfills.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... requirements for landfills. 270.21 Section 270.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Permit Application § 270.21 Specific part B information requirements for landfills. Except as otherwise provided in § 264.1, owners and operators of facilities that dispose of hazardous waste in landfills...

  19. General specifications covering requirements of aeronautic instruments

    NASA Technical Reports Server (NTRS)

    1917-01-01

    Report includes specifications for the use and production of instruments used in the navigation and operation of aircraft. Specifications are included for the following instruments: barometer or altimeter, compass, air speed meter, inclinometer, drift meter, tachometer, oil gauge, oil pressure gauge, gasoline gauge, gasoline flow indicator, distance indicator, barograph, angle of attack indicator, radiator temperature indicator, gasoline feed system pressure indicator, sextant, airplane director.

  20. 46 CFR 63.20-1 - Specific control system requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Specific control system requirements. 63.20-1 Section 63... AUXILIARY BOILERS Additional Control System Requirements § 63.20-1 Specific control system requirements. In... following requirements apply for specific control systems: (a) Primary safety control system....

  1. 46 CFR 63.20-1 - Specific control system requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Specific control system requirements. 63.20-1 Section 63... AUXILIARY BOILERS Additional Control System Requirements § 63.20-1 Specific control system requirements. In... following requirements apply for specific control systems: (a) Primary safety control system....

  2. 46 CFR 63.20-1 - Specific control system requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Specific control system requirements. 63.20-1 Section 63... AUXILIARY BOILERS Additional Control System Requirements § 63.20-1 Specific control system requirements. In... following requirements apply for specific control systems: (a) Primary safety control system....

  3. Security Clearances: Agencies Need Clearly Defined Policy for Determining Civilian Position Requirements

    DTIC Science & Technology

    2012-07-01

    branch has established policies and procedures for agencies to use when (1) first determining if federal civilian positions require a security...has established (1) policies and procedures for agencies to use when first determining whether federal civilian positions require a security...support for several nonservice DOD agencies and activities. For our first objective, to examine the extent to which the executive branch has established

  4. 77 FR 13617 - Agency Information Collection Activities: Customs Modernization Act Recordkeeping Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-07

    ... SECURITY U.S. Customs and Border Protection Agency Information Collection Activities: Customs Modernization Act Recordkeeping Requirements AGENCY: U.S. Customs and Border Protection (CBP), Department of... concerning the Customs Modernization Act Recordkeeping Requirements. This request for comment is being...

  5. System requirements specification for SMART structures mode

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Specified here are the functional and informational requirements for software modules which address the geometric and data modeling needs of the aerospace structural engineer. The modules are to be included as part of the Solid Modeling Aerospace Research Tool (SMART) package developed for the Vehicle Analysis Branch (VAB) at the NASA Langley Research Center (LaRC). The purpose is to precisely state what the SMART Structures modules will do, without consideration of how it will be done. Each requirement is numbered for reference in development and testing.

  6. IMCS reflight certification requirements and design specifications

    NASA Technical Reports Server (NTRS)

    1984-01-01

    The requirements for reflight certification are established. Software requirements encompass the software programs that are resident in the PCC, DEP, PDSS, EC, or any related GSE. A design approach for the reflight software packages is recommended. These designs will be of sufficient detail to permit the implementation of reflight software. The PDSS/IMC Reflight Certification system provides the tools and mechanisms for the user to perform the reflight certification test procedures, test data capture, test data display, and test data analysis. The system as defined will be structured to permit maximum automation of reflight certification procedures and test data analysis.

  7. PDSS/IMC requirements and functional specifications

    NASA Technical Reports Server (NTRS)

    1983-01-01

    The system (software and hardware) requirements for the Payload Development Support System (PDSS)/Image Motion Compensator (IMC) are provided. The PDSS/IMC system provides the capability for performing Image Motion Compensator Electronics (IMCE) flight software test, checkout, and verification and provides the capability for monitoring the IMC flight computer system during qualification testing for fault detection and fault isolation.

  8. 30 CFR 22.7 - Specific requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... diameter and are of reasonably thick glass. (4) Battery. If the detector is equipped with a battery, it... battery-type detectors is due chiefly to possible burning of the user by electrolyte that has spilled from the battery. MSHA, therefore, requires that: (1) Spilling of electrolyte. The battery shall be...

  9. Hitchhiker: Customer Accommodations and Requirements Specifications (CARS)

    NASA Technical Reports Server (NTRS)

    1992-01-01

    In 1984, NASA Headquarters established projects at the Goddard Space Flight Center (GSFC) and the Marshall Space Flight Center (MSFC) to develop quick-reaction carrier systems for low-cost 'flight of opportunity' or secondary payloads on the Space Transportation System (STS). One of these projects is the Hitchhiker (HH) Program. GSFC has developed a family of carrier equipment known as the Shuttle Payload of Opportunity Carrier (SPOC) system for mounting small payloads such as HH to the side of the Orbiter payload bay. The side-mounted HHs are referred to as Hitchhiker-G (HH-G). MSFC developed a cross-bay 'bridge-type' carrier structure called the Hitchhiker-M (HH-M). In 1987, responsibility for the HH-M carrier was transferred to and is now managed by the HH Project Office at the GSFC. The HH-M carrier now uses the same interchangeable SPOC avionics unit and the same electrical interfaces and services developed for HH-G. National Aeronautics and Space Administration (NASA) has created this document to acquaint potential HH system customers with the facilities NASA provides and the requirements which customers must satisfy to use these facilities. This publication defines interface items required for integrating customer equipment with the HH carrier system. Those items such as mounting equipment and electrical inputs and outputs; configuration, environmental, command, telemetry, and operational constraints are described as well as weight, power, and communications. The purpose of this publication is to help the customer understand essential integration documentation requirements and to prepare a Customer Payload Requirements (CPR) document.

  10. 7 CFR 765.351 - Requirements to obtain Agency consent.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... limitations relating to the type of loan involved as well as applicable requirements for appraisal, title... greater. Payments may be in equal or unequal installments with a balloon final installment; (3) The...

  11. 7 CFR 765.351 - Requirements to obtain Agency consent.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... limitations relating to the type of loan involved as well as applicable requirements for appraisal, title... greater. Payments may be in equal or unequal installments with a balloon final installment; (3) The...

  12. Engineering Specifications derived from Science Requirements

    NASA Technical Reports Server (NTRS)

    Stahl, H. Philip; Arnold, William; Bevan, Ryan M.; Smith, W. Scott; Kirk, Charles S.; Postman, Marc

    2013-01-01

    Advanced Mirror Technology Development (AMTD) is a multi-year effort to systematically mature to TRL-6 the critical technologies needed to produce 4-m or larger flight-qualified UVOIR mirrors by 2018 so that a viable mission can be considered by the 2020 Decadal Review. This technology must enable missions capable of both general astrophysics & ultra-high contrast observations of exoplanets. To accomplish our objective, we use a science-driven systems engineering approach. We mature technologies required to enable the highest priority science AND result in a high-performance low-cost low-risk system.

  13. Specific energy requirement for compacting corn stover.

    PubMed

    Mani, Sudhagar; Tabil, Lope G; Sokhansanj, Shahab

    2006-08-01

    Corn stover is a major crop residue for biomass conversion to produce chemicals and fuels. One of the problems associated with the supply of corn stover to conversion plants is the delivery of feedstock at a low cost. Corn stover has low bulk density and it is difficult to handle. In this study, chopped corn stover samples were compacted in a piston cylinder under three pressure levels (5, 10, 15 MPa) and at three moisture content levels (5%, 10%, 15% (wb)) to produce briquettes. The total energy requirement to compress and extrude briquette ranged from 12 to 30 MJ/t. The briquette density ranged from 650 to 950 kg/m3 increasing with pressure. Moisture content had also a significant effect on briquette density, durability and stability. Low moisture stover (5-10%) resulted in denser, more stable and more durable briquettes than high moisture stover (15%).

  14. 77 FR 6815 - Agency Information Collection Activities: Country of Origin Marking Requirements for Containers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-09

    ... Marking Requirements for Containers or Holders AGENCY: U.S. Customs and Border Protection (CBP... requirement concerning Country of Origin Marking Requirements for Containers or Holders. This request for...: Title: Country of Origin Marking Requirements for Containers or Holders. OMB Number: 1651-0057....

  15. 29 CFR 9.11 - Contracting agency requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... of a significant portion of workers who are not fluent in English, the notice shall be provided in both English and a language with which the employees are more familiar. Multiple foreign language notices are required where significant portions of the workforce speak different foreign languages...

  16. Structuring Formal Requirements Specifications for Reuse and Product Families

    NASA Technical Reports Server (NTRS)

    Heimdahl, Mats P. E.

    2001-01-01

    In this project we have investigated how formal specifications should be structured to allow for requirements reuse, product family engineering, and ease of requirements change, The contributions of this work include (1) a requirements specification methodology specifically targeted for critical avionics applications, (2) guidelines for how to structure state-based specifications to facilitate ease of change and reuse, and (3) examples from the avionics domain demonstrating the proposed approach.

  17. 42 CFR 435.903 - Adherence of local agencies to State plan requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN THE STATES, DISTRICT OF... Columbia General Methods of Administration § 435.903 Adherence of local agencies to State plan requirements. The agency must— (a) Have methods to keep itself currently informed of the adherence of local...

  18. 41 CFR 102-73.70 - Are Executive agencies required to acquire leased space by negotiation?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Are Executive agencies required to acquire leased space by negotiation? 102-73.70 Section 102-73.70 Public Contracts and Property... acquire leased space by negotiation? Yes, Executive agencies must acquire leased space by...

  19. 41 CFR 102-73.70 - Are Executive agencies required to acquire leased space by negotiation?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Are Executive agencies required to acquire leased space by negotiation? 102-73.70 Section 102-73.70 Public Contracts and Property... acquire leased space by negotiation? Yes, Executive agencies must acquire leased space by...

  20. 36 CFR 1222.24 - How do agencies establish recordkeeping requirements?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false How do agencies establish recordkeeping requirements? 1222.24 Section 1222.24 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF FEDERAL RECORDS Agency...

  1. 36 CFR 1222.24 - How do agencies establish recordkeeping requirements?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true How do agencies establish recordkeeping requirements? 1222.24 Section 1222.24 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF FEDERAL RECORDS Agency...

  2. 77 FR 27787 - Agency Information Collection Activities: Customs Modernization Act Recordkeeping Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-11

    ... SECURITY U.S. Customs and Border Protection Agency Information Collection Activities: Customs Modernization Act Recordkeeping Requirements AGENCY: U.S. Customs and Border Protection, Department of Homeland.... SUMMARY: U.S. Customs and Border Protection (CBP) of the Department of Homeland Security will...

  3. 78 FR 77484 - Agency Information Collection Activities: Documents Required Aboard Private Aircraft

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-23

    ... SECURITY U.S. Customs and Border Protection Agency Information Collection Activities: Documents Required Aboard Private Aircraft AGENCY: U.S. Customs and Border Protection (CBP), Department of Homeland Security... the Paperwork Reduction Act of 1995 (Pub. L. 104-13; 44 U.S.C. 3507). DATES: Written comments...

  4. 76 FR 76430 - Agency Information Collection Activities: Documents Required Aboard Private Aircraft

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-07

    ... SECURITY U.S. Customs and Border Protection Agency Information Collection Activities: Documents Required Aboard Private Aircraft AGENCY: U.S. Customs and Border Protection, Department of Homeland Security...-0058. SUMMARY: U.S. Customs and Border Protection (CBP) of the Department of Homeland Security will...

  5. 77 FR 23490 - Agency Information Collection Activities: Country of Origin Marking Requirements for Containers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-19

    ... SECURITY U.S. Customs and Border Protection Agency Information Collection Activities: Country of Origin Marking Requirements for Containers or Holders AGENCY: U.S. Customs and Border Protection, Department of... collection. SUMMARY: U.S. Customs and Border Protection (CBP) of the Department of Homeland Security will...

  6. 77 FR 10761 - Agency Information Collection Activities: Screening Requirements for Carriers

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-23

    ... SECURITY Customs and Border Protection Agency Information Collection Activities: Screening Requirements for Carriers AGENCY: U.S. Customs and Border Protection, Department of Homeland Security ACTION: 30-Day notice and request for comments; extension of an existing collection of information. SUMMARY: U.S....

  7. 40 CFR 761.372 - Specific requirements for relatively clean surfaces.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... clean surfaces. 761.372 Section 761.372 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... § 761.372 Specific requirements for relatively clean surfaces. For surfaces that do not appear dusty or... with clean rinse solvent such that the entire surfaces is very wet for 1 minute. Drain and contain...

  8. 40 CFR 761.372 - Specific requirements for relatively clean surfaces.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... clean surfaces. 761.372 Section 761.372 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... § 761.372 Specific requirements for relatively clean surfaces. For surfaces that do not appear dusty or... with clean rinse solvent such that the entire surfaces is very wet for 1 minute. Drain and contain...

  9. 40 CFR 60.3019 - What site-specific documentation is required?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What site-specific documentation is required? 60.3019 Section 60.3019 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... operators that addresses the nine topics described in paragraphs (a)(1) through (9) of this section....

  10. 40 CFR 60.2910 - What site-specific documentation is required?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What site-specific documentation is required? 60.2910 Section 60.2910 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... facility and readily accessible for all OSWI unit operators that addresses the nine topics described...

  11. 40 CFR 60.2095 - What site-specific documentation is required?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What site-specific documentation is required? 60.2095 Section 60.2095 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... ten topics described in paragraphs (a)(1) through (10) of this section. You must maintain...

  12. 40 CFR 60.2660 - What site-specific documentation is required?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What site-specific documentation is required? 60.2660 Section 60.2660 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... accessible for all CISWI unit operators that addresses the ten topics described in paragraphs (a)(1)...

  13. 40 CFR 60.2095 - What site-specific documentation is required?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 7 2013-07-01 2013-07-01 false What site-specific documentation is required? 60.2095 Section 60.2095 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... readily accessible for all CISWI unit operators that addresses the ten topics described in paragraphs...

  14. ONR BAA 06-007 System Requirements Specification. Version 1.1

    DTIC Science & Technology

    2007-04-10

    ONR BAA 06-007 System Requirements Specification Version 1.1 Mercury Data Systems 10 April 2007 Abstract This... Mercury Data Systems 4214 Beechwood Drive Suite 105 Greensboro, NC 27410 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY...the Confidentiality Statement of this document. Document Control This is a controlled document produced by Mercury Data Systems Inc. ( Mercury ). The

  15. 40 CFR 35.3550 - Specific capitalization grant agreement requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... requirements. 35.3550 Section 35.3550 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND... payments. A State must agree to accept capitalization grant payments in accordance with a payment schedule... made in an amount equal to the amount of each capitalization grant payment and accompanying State...

  16. 44 CFR 302.8 - Waiver of “single” State agency requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS CIVIL DEFENSE-STATE AND LOCAL EMERGENCY MANAGEMENT... requires that plans for civil defense of the United States be administered or supervised by a single...

  17. 44 CFR 302.8 - Waiver of “single” State agency requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS CIVIL DEFENSE-STATE AND LOCAL EMERGENCY MANAGEMENT... requires that plans for civil defense of the United States be administered or supervised by a single...

  18. 44 CFR 302.8 - Waiver of “single” State agency requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS CIVIL DEFENSE-STATE AND LOCAL EMERGENCY MANAGEMENT... requires that plans for civil defense of the United States be administered or supervised by a single...

  19. 44 CFR 302.8 - Waiver of “single” State agency requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS CIVIL DEFENSE-STATE AND LOCAL EMERGENCY MANAGEMENT... requires that plans for civil defense of the United States be administered or supervised by a single...

  20. Prerequisites to Deriving Formal Specifications from Natural Language Requirements.

    DTIC Science & Technology

    1981-10-01

    Special 19. KEY WORDS (Continue on reverse side Ii nocessary and Identify by block number) formal specifications, English specifications, modules, software... English specifications and formal specifications of modules are complementary and since formal specifications require so much effort to write, our...involved four areas of work. The firtt is,A\\ comparing English descriptions with formal specifications of the same software module. This work is now complete

  1. 49 CFR 179.401-1 - Individual specification requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specification for Cryogenic Liquid Tank Car Tanks and Seamless Steel Tanks (Classes DOT-113 and... specification requirements for the inner tank and its appurtenances are as follows: DOT specification...

  2. 49 CFR 179.401-1 - Individual specification requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specification for Cryogenic Liquid Tank Car Tanks and Seamless Steel Tanks (Classes DOT-113 and... specification requirements for the inner tank and its appurtenances are as follows: DOT specification...

  3. 49 CFR 179.401-1 - Individual specification requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specification for Cryogenic Liquid Tank Car Tanks and Seamless Steel Tanks (Classes DOT-113 and... specification requirements for the inner tank and its appurtenances are as follows: DOT specification...

  4. 49 CFR 179.401-1 - Individual specification requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specification for Cryogenic Liquid Tank Car Tanks and Seamless Steel Tanks (Classes DOT-113 and... specification requirements for the inner tank and its appurtenances are as follows: DOT specification...

  5. Using SCOR as a Supply Chain Management Framework for Government Agency Contract Requirements

    NASA Technical Reports Server (NTRS)

    Paxton, Joseph; Tucker, Brian

    2010-01-01

    This paper will present a model that uses the Supply-Chain Operations Reference (SCOR) model as a foundation for a framework to illustrate the information needed throughout a product lifecycle to support a healthy supply chain management function and the subsequent contract requirements to enable it. It will also show where in the supply chain the information must be extracted. The ongoing case study used to exemplify the model is NASA's (National Aeronautics and Space Administration) Ares I program for human spaceflight. Effective supply chain management and contract requirements are ongoing opportunities for continuous improvement within government agencies, specifically development of systems for human spaceflight operations. Multiple reports from the Government Accountability Office (GAO) reinforce this importance. The SCOR model is a framework for describing a supply chain with process building blocks and business activities. It provides a set of metrics for measuring supply chain performance and best practices for continuously improving. This paper expands the application of the SCOR to also provide the framework for defining information needed from different levels of the supply chain and at different phases of the lifecycle. These needs can be incorporated into contracts to enable more effective supply chain management. Depending on the phase of the lifecycle, effective supply chain management will require involvement from different levels of the organization and different levels of the supply chain.

  6. 41 CFR 302-1.102 - Are agencies required to report their employee relocation activities to GSA?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 4 2011-07-01 2011-07-01 false Are agencies required to... Property Management Federal Travel Regulation System RELOCATION ALLOWANCES INTRODUCTION 1-GENERAL RULES Requirement to Report Agency Data for Employee Relocation § 302-1.102 Are agencies required to report...

  7. 41 CFR 302-1.102 - Are agencies required to report their employee relocation activities to GSA?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 41 Public Contracts and Property Management 4 2012-07-01 2012-07-01 false Are agencies required to... Property Management Federal Travel Regulation System RELOCATION ALLOWANCES INTRODUCTION 1-GENERAL RULES Requirement to Report Agency Data for Employee Relocation § 302-1.102 Are agencies required to report...

  8. 41 CFR 302-1.102 - Are agencies required to report their employee relocation activities to GSA?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 41 Public Contracts and Property Management 4 2014-07-01 2014-07-01 false Are agencies required to... Property Management Federal Travel Regulation System RELOCATION ALLOWANCES INTRODUCTION 1-GENERAL RULES Requirement to Report Agency Data for Employee Relocation § 302-1.102 Are agencies required to report...

  9. 41 CFR 302-1.102 - Are agencies required to report their employee relocation activities to GSA?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 4 2013-07-01 2012-07-01 true Are agencies required to... Property Management Federal Travel Regulation System RELOCATION ALLOWANCES INTRODUCTION 1-GENERAL RULES Requirement to Report Agency Data for Employee Relocation § 302-1.102 Are agencies required to report...

  10. 49 CFR 173.62 - Specific packaging requirements for explosives.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 2 2012-10-01 2012-10-01 false Specific packaging requirements for explosives... Class 1 § 173.62 Specific packaging requirements for explosives. (a) Except as provided in § 173.7 of this subchapter, when the § 172.101 Table specifies that an explosive must be packaged in...

  11. 49 CFR 173.62 - Specific packaging requirements for explosives.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 2 2013-10-01 2013-10-01 false Specific packaging requirements for explosives... Class 1 § 173.62 Specific packaging requirements for explosives. (a) Except as provided in § 173.7 of this subchapter, when the § 172.101 Table specifies that an explosive must be packaged in...

  12. 49 CFR 173.62 - Specific packaging requirements for explosives.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 2 2011-10-01 2011-10-01 false Specific packaging requirements for explosives... Class 1 § 173.62 Specific packaging requirements for explosives. (a) Except as provided in § 173.7 of this subchapter, when the § 172.101 Table specifies that an explosive must be packaged in...

  13. From Goal-Oriented Requirements to Event-B Specifications

    NASA Technical Reports Server (NTRS)

    Aziz, Benjamin; Arenas, Alvaro E.; Bicarregui, Juan; Ponsard, Christophe; Massonet, Philippe

    2009-01-01

    In goal-oriented requirements engineering methodologies, goals are structured into refinement trees from high-level system-wide goals down to fine-grained requirements assigned to specific software/ hardware/human agents that can realise them. Functional goals assigned to software agents need to be operationalised into specification of services that the agent should provide to realise those requirements. In this paper, we propose an approach for operationalising requirements into specifications expressed in the Event-B formalism. Our approach has the benefit of aiding software designers by bridging the gap between declarative requirements and operational system specifications in a rigorous manner, enabling powerful correctness proofs and allowing further refinements down to the implementation level. Our solution is based on verifying that a consistent Event-B machine exhibits properties corresponding to requirements.

  14. Asbestos-in-Schools: A Guide to New Federal Requirements for Local Education Agencies.

    ERIC Educational Resources Information Center

    Environmental Protection Agency, Washington, DC. Office of Toxic Substances.

    In 1986, the Asbestos Hazard Emergency Response Act (AHERA) was signed into law requiring the Environmental Protection Agency (EPA) to develop regulations which provide a comprehensive framework for addressing asbestos problems in secondary and elementary schools. The new rule, The Asbestos-Containing Materials in Schools Rule, requires all…

  15. 78 FR 73237 - Reports, Forms and Record Keeping Requirements Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-05

    ... National Highway Traffic Safety Administration Reports, Forms and Record Keeping Requirements Agency... Regulatory Affairs, Office of Management and Budget, 725-17th Street NW., Washington, DC 20503, Attention... of 49 CFR Part 512. Requesters are not required to keep copies of any records or reports ]...

  16. 78 FR 67212 - Reports, Forms and Record Keeping Requirements; Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-08

    ... National Highway Traffic Safety Administration Reports, Forms and Record Keeping Requirements; Agency... has submitted required information shall keep its entry current, accurate and complete by submitting... Regulatory Affairs, Office of Management and Budget, 725 17th Street NW., Washington, DC 20503,...

  17. 76 FR 26750 - Agency Information Collection Activities: Documentation Requirements for Articles Entered Under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-09

    ... Requirements for Articles Entered Under Various Special Tariff Treatment Provisions AGENCY: U.S. Customs and... Articles Entered Under Various Special Tariff Treatment Provisions. This request for comment is being made... Requirements for Articles Entered Under Various Special Tariff Treatment Provisions. OMB Number:...

  18. 76 FR 39416 - Agency Information Collection Activities: Documentation Requirements for Articles Entered Under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-06

    ... Requirements for Articles Entered Under Various Special Tariff Treatment Provisions AGENCY: U.S. Customs and... Treatment Provisions. This is a proposed extension of an information collection that was previously approved.... Title: Documentation Requirements for Articles Entered Under Various Special Tariff Treatment...

  19. 75 FR 80287 - Environmental Protection Agency Implementation of OMB Guidance on Drug-Free Workplace Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-22

    ... only to those regulatory actions that concern health or safety risks, such that the analysis required... than an individual notify about a criminal drug conviction? Subpart C--Requirements for Recipients Who... individual notify about a criminal drug conviction? Subpart D--Responsibilities of Agency Awarding...

  20. Electrical Bonding: A Survey of Requirement, Methods, and Specifications

    NASA Technical Reports Server (NTRS)

    Evans, R. W.

    1998-01-01

    This document provides information helpful to engineers imposing electrical bonding requirements, reviewing waiver requests, or modifying specifications on various space programs. Electrical bonding specifications and some of the processes used in the United States have been reviewed. This document discusses the specifications, the types of bonds, the intent of each, and the basic requirements where possible. Additional topics discussed are resistance versus impedance, bond straps, corrosion, finishes, and special applications.

  1. 36 CFR 1232.14 - What requirements must an agency meet before it transfers records to a records storage facility?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... agency meet before it transfers records to a records storage facility? 1232.14 Section 1232.14 Parks... RECORDS TO RECORDS STORAGE FACILITIES § 1232.14 What requirements must an agency meet before it transfers records to a records storage facility? An agency must meet the following requirements before it...

  2. 36 CFR 1232.14 - What requirements must an agency meet before it transfers records to a records storage facility?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... agency meet before it transfers records to a records storage facility? 1232.14 Section 1232.14 Parks... RECORDS TO RECORDS STORAGE FACILITIES § 1232.14 What requirements must an agency meet before it transfers records to a records storage facility? An agency must meet the following requirements before it...

  3. UML activity diagrams in requirements specification of logic controllers

    NASA Astrophysics Data System (ADS)

    Grobelna, Iwona; Grobelny, Michał

    2015-12-01

    Logic controller specification can be prepared using various techniques. One of them is the wide understandable and user-friendly UML language and its activity diagrams. Using formal methods during the design phase increases the assurance that implemented system meets the project requirements. In the approach we use the model checking technique to formally verify a specification against user-defined behavioral requirements. The properties are usually defined as temporal logic formulas. In the paper we propose to use UML activity diagrams in requirements definition and then to formalize them as temporal logic formulas. As a result, UML activity diagrams can be used both for logic controller specification and for requirements definition, what simplifies the specification and verification process.

  4. Software Requirements Specification Verifiable Fuel Cycle Simulation (VISION) Model

    SciTech Connect

    D. E. Shropshire; W. H. West

    2005-11-01

    The purpose of this Software Requirements Specification (SRS) is to define the top-level requirements for a Verifiable Fuel Cycle Simulation Model (VISION) of the Advanced Fuel Cycle (AFC). This simulation model is intended to serve a broad systems analysis and study tool applicable to work conducted as part of the AFCI (including costs estimates) and Generation IV reactor development studies.

  5. 49 CFR 179.101-1 - Individual specification requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 3 2013-10-01 2013-10-01 false Individual specification requirements. 179.101-1 Section 179.101-1 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR...

  6. 49 CFR 179.201-1 - Individual specification requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 3 2012-10-01 2012-10-01 false Individual specification requirements. 179.201-1 Section 179.201-1 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR...

  7. 49 CFR 179.101-1 - Individual specification requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 3 2012-10-01 2012-10-01 false Individual specification requirements. 179.101-1 Section 179.101-1 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR...

  8. 49 CFR 179.201-1 - Individual specification requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 3 2013-10-01 2013-10-01 false Individual specification requirements. 179.201-1 Section 179.201-1 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR...

  9. 49 CFR 179.201-1 - Individual specification requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 3 2011-10-01 2011-10-01 false Individual specification requirements. 179.201-1 Section 179.201-1 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR...

  10. 49 CFR 179.101-1 - Individual specification requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 3 2014-10-01 2014-10-01 false Individual specification requirements. 179.101-1 Section 179.101-1 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR...

  11. 49 CFR 179.101-1 - Individual specification requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 3 2011-10-01 2011-10-01 false Individual specification requirements. 179.101-1 Section 179.101-1 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR...

  12. 76 FR 12645 - Ownership Limitations and Governance Requirements for Security-Based Swap Clearing Agencies...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... COMMISSION 17 CFR Part 242 RIN 3235-AK74 Ownership Limitations and Governance Requirements for Security... or appropriate to improve the governance of, or to mitigate systemic risk, promote competition or... in and the governance of security-based swap clearing agencies, SB SEFs and SBS...

  13. 75 FR 30098 - Reports, Forms and RecordKeeping Requirements; Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-28

    ... National Highway Traffic Safety Administration Reports, Forms and RecordKeeping Requirements; Agency...-17th Street, NW., Washington, DC 20503, Attention NHTSA Desk Officer. Comments are invited on: whether... information on respondents, including the use of automated collection techniques or other forms of...

  14. 76 FR 8399 - Reports, Forms and Record Keeping Requirements; Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-14

    ... National Highway Traffic Safety Administration Reports, Forms and Record Keeping Requirements; Agency...., Washington, DC 20503, Attention NHTSA Desk Officer. Comments are invited on: Whether the proposed collection..., including the use of automated collection techniques or other forms of information technology. A comment...

  15. 75 FR 16895 - Reports, Forms and Record Keeping Requirements; Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

    ... National Highway Traffic Safety Administration Reports, Forms and Record Keeping Requirements; Agency... Street, NW., Washington, DC 20503, Attention: NHTSA Desk Officer. FOR FURTHER INFORMATION CONTACT: Ms... maintenance costs of keeping the data up to date, etc. as tests come in throughout the year. In the...

  16. 76 FR 76218 - Reports, Forms and Record Keeping Requirements; Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-06

    ... National Highway Traffic Safety Administration Reports, Forms and Record Keeping Requirements; Agency... respondents, including the use of automated collection techniques or other forms of information technology. A... Budget, 725-17th Street NW., Washington, DC 20503, Attention NHTSA Desk Officer. Issued in Washington,...

  17. 75 FR 19453 - Reports, Forms and Record Keeping Requirements; Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-14

    ... National Highway Traffic Safety Administration Reports, Forms and Record Keeping Requirements; Agency... Officer, Office of Management and Budget, Office of Information and Regulatory Affairs, Attention: by fax... automated collection techniques or other forms of information technology. A Comment to OMB is most...

  18. 76 FR 35266 - Reports, Forms and Record Keeping Requirements; Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-16

    ... National Highway Traffic Safety Administration Reports, Forms and Record Keeping Requirements; Agency... Management and Budget, 725 17th Street, NW., Washington, DC 20503, Attention NHTSA Desk Officer. Comments are... collection of information on respondents, including the use of automated collection techniques or other...

  19. 75 FR 36150 - Reports, Forms and Record Keeping Requirements; Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-24

    ... National Highway Traffic Safety Administration Reports, Forms and Record Keeping Requirements; Agency... 17th Street, NW., Washington, DC 20503, Attention NHTSA Desk Officer. Comments are invited on: Whether... information on respondents, including the use of automated collection techniques or other forms of...

  20. 9 CFR 201.29 - Market agencies, packers and dealers required to file and maintain bonds.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Market agencies, packers and dealers required to file and maintain bonds. 201.29 Section 201.29 Animals and Animal Products GRAIN INSPECTION... dealers to purchase livestock for slaughter only, shall execute and maintain a reasonable bond on...

  1. 9 CFR 201.29 - Market agencies, packers and dealers required to file and maintain bonds.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Market agencies, packers and dealers required to file and maintain bonds. 201.29 Section 201.29 Animals and Animal Products GRAIN INSPECTION... dealers to purchase livestock for slaughter only, shall execute and maintain a reasonable bond on...

  2. 36 CFR 1222.26 - What are the general recordkeeping requirements for agency programs?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false What are the general recordkeeping requirements for agency programs? 1222.26 Section 1222.26 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF FEDERAL...

  3. 36 CFR 1222.26 - What are the general recordkeeping requirements for agency programs?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false What are the general recordkeeping requirements for agency programs? 1222.26 Section 1222.26 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF FEDERAL...

  4. 36 CFR 1222.26 - What are the general recordkeeping requirements for agency programs?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false What are the general recordkeeping requirements for agency programs? 1222.26 Section 1222.26 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF FEDERAL...

  5. 36 CFR 1222.26 - What are the general recordkeeping requirements for agency programs?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false What are the general recordkeeping requirements for agency programs? 1222.26 Section 1222.26 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF FEDERAL...

  6. 36 CFR 1222.26 - What are the general recordkeeping requirements for agency programs?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true What are the general recordkeeping requirements for agency programs? 1222.26 Section 1222.26 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF FEDERAL...

  7. 76 FR 79688 - Agency Recordkeeping/Reporting Requirements Under Emergency Review by the Office of Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-22

    ... HUMAN SERVICES Administration for Children and Families Agency Recordkeeping/Reporting Requirements... U.S. Department of Health and Human Services (HHS) have launched a national evaluation called the... characteristics including: The type of home visiting model, geography, urbanicity, target population, and...

  8. 75 FR 31447 - Agency Recordkeeping/Reporting Requirements Under Emergency Review by the Office of Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-03

    ... HUMAN SERVICES Administration for Children and Families Agency Recordkeeping/Reporting Requirements Under Emergency Review by the Office of Management and Budget Title: State Personal Responsibility... Application to include program narrative........ 59 1 40 2360 Performance Progress Reports 59 2 10 1180 Year...

  9. 75 FR 65881 - Ownership Limitations and Governance Requirements for Security-Based Swap Clearing Agencies...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-26

    ... executable end-of-day settlement prices. Since there is currently no exchange or other venue that publishes security-based swap prices, the Commission has required security-based swap clearing agencies to publish end-of-day settlement prices and any other prices with respect to cleared security-based swaps...

  10. 41 CFR 102-3.185 - What does this subpart require agencies to do?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Administration (NAPA) under an agreement between the agency and an academy, if such advice or recommendation was...) of the Act; or (3) In the case of NAPA, the academy certifies that it has complied substantially with... with NAS or NAPA that are consistent with the requirements of this subpart to obtain advice...

  11. 78 FR 14095 - Agency Recordkeeping/Reporting Requirements Under Emergency Review by the Office of Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-04

    ... Administration for Children and Families' (ACF) 196 form for periodic financial reporting under the Temporary... required by Congress. Financial reporting under the TANF program is governed by 45 CFR part 265. This... HUMAN SERVICES Administration for Children and Families Agency Recordkeeping/Reporting...

  12. 41 CFR 102-3.185 - What does this subpart require agencies to do?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false What does this subpart require agencies to do? 102-3.185 Section 102-3.185 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION GENERAL 3-FEDERAL...

  13. 41 CFR 102-3.185 - What does this subpart require agencies to do?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false What does this subpart require agencies to do? 102-3.185 Section 102-3.185 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION GENERAL 3-FEDERAL...

  14. 41 CFR 102-3.185 - What does this subpart require agencies to do?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false What does this subpart require agencies to do? 102-3.185 Section 102-3.185 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION GENERAL 3-FEDERAL...

  15. 34 CFR 682.414 - Records, reports, and inspection requirements for guaranty agency programs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Records, reports, and inspection requirements for guaranty agency programs. 682.414 Section 682.414 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION FEDERAL FAMILY...

  16. 41 CFR 102-74.60 - Are Federal agencies required to give blind vendors priority in operating cafeterias?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... required to give blind vendors priority in operating cafeterias? 102-74.60 Section 102-74.60 Public....60 Are Federal agencies required to give blind vendors priority in operating cafeterias? Yes. Federal agencies are required to give Randolph-Sheppard vendors priority in the operation of cafeterias when...

  17. Specifications and use of controlled low-strength material by state transportation agencies

    SciTech Connect

    Riggs, E.H.; Keck, R.H.

    1998-10-01

    Controlled low strength material, CLSM, was not used by state transportation agencies until recently, although its use in general construction dates back to the early 1970`s. The documentation of its present inclusion by many states is important in the progress of the technology of this relatively new material. States surveyed include Alabama, Florida, Georgia, North Carolina, South Carolina, and Virginia. The individual specifications are reviewed and compared. Testing methods are also discussed, along with representative data from laboratory and field test reports. Finally, a composite specification is suggested based on the consensus of the ones reviewed.

  18. 19 CFR 134.42 - Specific method may be required.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Specific method may be required. 134.42 Section 134.42 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY COUNTRY OF ORIGIN MARKING Method and Location of Marking Imported Articles §...

  19. 19 CFR 134.42 - Specific method may be required.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Specific method may be required. 134.42 Section 134.42 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY COUNTRY OF ORIGIN MARKING Method and Location of Marking Imported Articles §...

  20. 49 CFR 178.35 - General requirements for specification cylinders.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) Inspections and analyses. Chemical analyses and tests required by this subchapter must be made within the... specification by— (i) Making a chemical analysis of each heat of material; (ii) Obtaining a certified chemical...) Obtaining samples for all tests and check chemical analyses (Note: Recommended locations for test...

  1. 18 CFR 12.35 - Specific inspection requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Specific inspection requirements. 12.35 Section 12.35 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT SAFETY OF WATER POWER PROJECTS...

  2. 18 CFR 12.35 - Specific inspection requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Specific inspection requirements. 12.35 Section 12.35 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT SAFETY OF WATER POWER PROJECTS...

  3. 18 CFR 12.35 - Specific inspection requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Specific inspection requirements. 12.35 Section 12.35 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT SAFETY OF WATER POWER PROJECTS...

  4. 49 CFR 179.201-1 - Individual specification requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Individual specification requirements. 179.201-1 Section 179.201-1 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS...

  5. Draft Geologic Disposal Requirements Basis for STAD Specification

    SciTech Connect

    Ilgen, Anastasia G.; Bryan, Charles R.; Hardin, Ernest

    2015-03-25

    This document provides the basis for requirements in the current version of Performance Specification for Standardized Transportation, Aging, and Disposal Canister Systems, (FCRD-NFST-2014-0000579) that are driven by storage and geologic disposal considerations. Performance requirements for the Standardized Transportation, Aging, and Disposal (STAD) canister are given in Section 3.1 of that report. Here, the requirements are reviewed and the rationale for each provided. Note that, while FCRD-NFST-2014-0000579 provides performance specifications for other components of the STAD storage system (e.g. storage overpack, transfer and transportation casks, and others), these have no impact on the canister performance during disposal, and are not discussed here.

  6. Integration of site-specific health information: Agency for Toxic Substances and Disease Registry health assessments

    SciTech Connect

    Lesperance, A.M.; Siegel, M.R.

    1990-12-01

    The Agency for Toxic Substances and Disease Registry is required to conduct a health assessment of any site that is listed on or proposed for the US Environmental Protection Agency's National Priorities List. Sixteen US Department of Energy (DOE) sites currently fall into this category. Health assessments contain a qualitative description of impacts to public health and the environment from hazardous waste sites, as well as recommendations for actions to mitigate or eliminate risk. Because these recommendations may have major impacts on compliance activities at DOE facilities, the health assessments are an important source of information for the monitoring activities of DOE's Office of Environmental Compliance (OEC). This report provides an overview of the activities involved in preparing the health assessment, its role in environmental management, and its key elements.

  7. 41 CFR 102-73.250 - Are agencies required to adhere to the policies for locating Federal facilities when purchasing...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Are agencies required to adhere to the policies for locating Federal facilities when purchasing buildings? 102-73.250 Section 102... Condemnation Buildings § 102-73.250 Are agencies required to adhere to the policies for locating...

  8. 41 CFR 102-73.250 - Are agencies required to adhere to the policies for locating Federal facilities when purchasing...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Are agencies required to adhere to the policies for locating Federal facilities when purchasing buildings? 102-73.250 Section 102... Condemnation Buildings § 102-73.250 Are agencies required to adhere to the policies for locating...

  9. 34 CFR 222.21 - What requirements must a local educational agency meet concerning Federal acquisition of real...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... concerning Federal acquisition of real property within the local educational agency? 222.21 Section 222.21... the Act § 222.21 What requirements must a local educational agency meet concerning Federal acquisition... the requirements in subpart A of this part and § 222.22. In addition, unless otherwise provided...

  10. Liver-specific activities of FGF19 require Klotho beta.

    PubMed

    Lin, Benjamin C; Wang, Manping; Blackmore, Craig; Desnoyers, Luc R

    2007-09-14

    Hepatocyte function is regulated by members of the fibroblast growth factor (FGF) family of proteins, but little is known about the specific molecular mechanisms of this endocrine pathway. FGF19 regulates bile acid homeostasis and gall bladder filling; FGF19 binds only to FGF receptor 4 (FGFR4), but its liver-specific activity cannot be explained solely by the distribution of this receptor. Although it has been suggested that Klotho beta (KLB) may have a role in mediating FGF19 activity, we have provided for the first time definitive evidence that KLB is required for FGF19 binding to FGFR4, intracellular signaling, and downstream modulation of gene expression. We have shown that FGFR4 is widely distributed in mouse, whereas KLB distribution is more restricted. Liver was the only organ in which both genes were abundantly expressed. We show that in mice, FGF19 injection triggers liver-specific induction of c-Fos and repression of CYP7A1. The tissue-specific activity of FGF19 supports the unique intersection of KLB and FGFR4 distribution in liver. These studies define KLB as a novel FGFR4 coreceptor required for FGF19 liver specific functions.

  11. Rationale for windshield glass system specification requirements for shuttle orbiter

    NASA Technical Reports Server (NTRS)

    Hayashida, K.; King, G. L.; Tesinsiky, J.; Wittenburg, D. R.

    1972-01-01

    A preliminary procurement specification for the space shuttle orbiter windshield pane, and some of the design considerations and rationale leading to its development are presented. The windshield designer is given the necessary methods and procedures for assuring glass pane structural integrity by proof test. These methods and procedures are fully developed for annealed and thermally tempered aluminosilicate, borosilicate, and soda lime glass and for annealed fused silica. Application of the method to chemically tempered glass is considered. Other considerations are vision requirements, protection against bird impact, hail, frost, rain, and meteoroids. The functional requirements of the windshield system during landing, ferrying, boost, space flight, and entry are included.

  12. Software requirements: Guidance and control software development specification

    NASA Technical Reports Server (NTRS)

    Withers, B. Edward; Rich, Don C.; Lowman, Douglas S.; Buckland, R. C.

    1990-01-01

    The software requirements for an implementation of Guidance and Control Software (GCS) are specified. The purpose of the GCS is to provide guidance and engine control to a planetary landing vehicle during its terminal descent onto a planetary surface and to communicate sensory information about that vehicle and its descent to some receiving device. The specification was developed using the structured analysis for real time system specification methodology by Hatley and Pirbhai and was based on a simulation program used to study the probability of success of the 1976 Viking Lander missions to Mars. Three versions of GCS are being generated for use in software error studies.

  13. Analyzing Tabular and State-Transition Requirements Specifications in PVS

    NASA Technical Reports Server (NTRS)

    Owre, Sam; Rushby, John; Shankar, Natarajan

    1997-01-01

    We describe PVS's capabilities for representing tabular specifications of the kind advocated by Parnas and others, and show how PVS's Type Correctness Conditions (TCCs) are used to ensure certain well-formedness properties. We then show how these and other capabilities of PVS can be used to represent the AND/OR tables of Leveson and the Decision Tables of Sherry, and we demonstrate how PVS's TCCs can expose and help isolate errors in the latter. We extend this approach to represent the mode transition tables of the Software Cost Reduction (SCR) method in an attractive manner. We show how PVS can check these tables for well-formedness, and how PVS's model checking capabilities can be used to verify invariants and reachability properties of SCR requirements specifications, and inclusion relations between the behaviors of different specifications. These examples demonstrate how several capabilities of the PVS language and verification system can be used in combination to provide customized support for specific methodologies for documenting and analyzing requirements. Because they use only the standard capabilities of PVS, users can adapt and extend these customizations to suit their own needs. Those developing dedicated tools for individual methodologies may find these constructions in PVS helpful for prototyping purposes, or as a useful adjunct to a dedicated tool when the capabilities of a full theorem prover are required. The examples also illustrate the power and utility of an integrated general-purpose system such as PVS. For example, there was no need to adapt or extend the PVS model checker to make it work with SCR specifications described using the PVS TABLE construct: the model checker is applicable to any transition relation, independently of the PVS language constructs used in its definition.

  14. 76 FR 81955 - Assessment Questionnaire-IP Sector Specific Agency Risk Self Assessment Tool (IP-SSARSAT)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... SECURITY Assessment Questionnaire--IP Sector Specific Agency Risk Self Assessment Tool (IP-SSARSAT) AGENCY... Information Collection Request: 1670-NEW. SUMMARY: The Department of Homeland Security (DHS), National... received must include the words ``Department of Homeland Security'' and the docket ] number for this...

  15. 77 FR 33227 - Assessment Questionnaire-IP Sector Specific Agency Risk Self Assessment Tool (IP-SSARSAT)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-05

    ... SECURITY Assessment Questionnaire--IP Sector Specific Agency Risk Self Assessment Tool (IP-SSARSAT) AGENCY... Information Collection Request, 1670-NEW. SUMMARY: The Department of Homeland Security (DHS), National... words ``Department of Homeland Security'' and the docket number for this action. Comments received...

  16. Requirements specification for nickel cadmium battery expert system

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The requirements for performance, design, test, and qualification of a computer program identified as NICBES, Nickel Cadmium Battery Expert System, is established. The specific spacecraft power system configuration selected was the Hubble Space Telescope (HST) Electrical Power System (EPS) Testbed. Power for the HST comes from a system of 13 Solar Panel Arrays (SPAs) linked to 6 Nickel Cadmium Batteries which are connected to 3 Busses. An expert system, NICBES, will be developed at Martin Marietta Aerospace to recognize a testbed anomaly, identify the malfunctioning component and recommend a course of action. Besides fault diagnosis, NICBES will be able to evaluate battery status, give advice on battery status and provide decision support for the operator. These requirements are detailed.

  17. Incubator Display Software Cost Reduction Toolset Software Requirements Specification

    NASA Technical Reports Server (NTRS)

    Moran, Susanne; Jeffords, Ralph

    2005-01-01

    The Incubator Display Software Requirements Specification was initially developed by Intrinsyx Technologies Corporation (Intrinsyx) under subcontract to Lockheed Martin, Contract Number NAS2-02090, for the National Aeronautics and Space Administration (NASA) Ames Research Center (ARC) Space Station Biological Research Project (SSBRP). The Incubator Display is a User Payload Application (UPA) used to control an Incubator subrack payload for the SSBRP. The Incubator Display functions on-orbit as part of the subrack payload laptop, on the ground as part of the Communication and Data System (CDS) ground control system, and also as part of the crew training environment.

  18. Reengineering DOD-STD-2167A Requirements Specifications

    DTIC Science & Technology

    1994-08-01

    DTIC1111111111111111101111" ELECT E ’•S SEP 1 6 1994 FINAL REPORT REENGINEERING DOD- STD -2167A REQUIREMENTS SPECIFICATIONS CONTRACT N00014-92.C.0242 OFFICE OF...Dist Special Canwacg Number N00014-92-C0242 Fna Report Reuglomeegtug DOD- STD -2167A Requirhmais SpecOmladom 1. INTRODUCTION This is the Final Report...under contract N00014-92-C-0242. This contract covered work in two steps: 1. Design of the automatic system for generating DoD- STD -2167A Software

  19. Energy storage specification requirements for hybrid-electric vehicle

    SciTech Connect

    Burke, A.F.

    1993-09-01

    A study has been made of energy storage unit requirements for hybrid-electric vehicles. The drivelines for these vehicles included both primary energy storage units and/or pulse power units. The primary energy storage units were sized to provide ``primary energy`` ranges up to 60 km. The total power capability of the drivelines were such that the vehicles had 0 to 100 km/h acceleration times of 10 to 12 s. The power density requirements for primary energy storage devices to be used in hybrid vehicles are much higher than that for devices to be used in electric vehicles. The energy density and power density requirements for pulse-power devices for hybrid vehicles, are not much different than those in an electric vehicle. The cycle life requirements for primary energy-storage units for hybrid vehicles are about double that for electric vehicles, because of the reduced size of the storage units in the hybrid vehicles. The cycle life for pulse-power devices for hybrid vehicles is about the same as for electric vehicles having battery load leveling. Because of the need for additional components in the hybrid driveline, the cost of the energy storage units in hybrid vehicles should be much less (at least a factor of two) than those in electric vehicles. There are no presently available energy storage units that meet all the specifications for hybrid vehicle applications, but ultracapacitors and bipolar lead-acid batteries are under development that have the potential for meeting them. If flywheel systems having a mechanical system energy density of 40 to 50 W{center_dot}h/kg and an electrical system power density of 2 to 3 kw/kg can be developed, they would have the potential of meeting specifications for primary storage and pulse power units.

  20. Energy storage specification requirements for hybrid-electric vehicle

    NASA Astrophysics Data System (ADS)

    Burke, A. F.

    1993-09-01

    A study has been made of energy storage unit requirements for hybrid-electric vehicles. The drivelines for these vehicles included both primary energy storage units and/or pulse power units. The primary energy storage units were sized to provide 'primary energy' ranges up to 60 km. The total power capability of the drivelines were such that the vehicles had 0 to 100 km/h acceleration times of 10 to 12 s. The power density requirements for primary energy storage devices to be used in hybrid vehicles are much higher than that for devices to be used in electric vehicles. The energy density and power density requirements for pulse-power devices for hybrid vehicles, are not much different than those in an electric vehicle. The cycle life requirements for primary energy-storage units for hybrid vehicles are about double that for electric vehicles, because of the reduced size of the storage units in the hybrid vehicles. The cycle life for pulse-power devices for hybrid vehicles is about the same as for electric vehicles having battery load leveling. Because of the need for additional components in the hybrid driveline, the cost of the energy storage units in hybrid vehicles should be much less (at least a factor of two) than those in electric vehicles. There are no presently available energy storage units that meet all the specifications for hybrid vehicle applications, but ultracapacitors and bipolar lead-acid batteries are under development that have the potential for meeting them. If flywheel systems having a mechanical system energy density of 40 to 50 W(center dot)h/kg and an electrical system power density of 2 to 3 kw/kg can be developed, they would have the potential of meeting specifications for primary storage and pulse power units.

  1. 34 CFR 403.100 - What are the requirements for designating a State corrections educational agency to administer...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... corrections educational agency to administer the Programs for Criminal Offenders? 403.100 Section 403.100... ADULT EDUCATION, DEPARTMENT OF EDUCATION STATE VOCATIONAL AND APPLIED TECHNOLOGY EDUCATION PROGRAM What... § 403.100 What are the requirements for designating a State corrections educational agency to...

  2. 20 CFR 411.410 - Does each referral from an EN to a State VR agency require its own agreement?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Does each referral from an EN to a State VR agency require its own agreement? 411.410 Section 411.410 Employees' Benefits SOCIAL SECURITY...' Participation Agreements Between Employment Networks and State Vr Agencies § 411.410 Does each referral from...

  3. 20 CFR 411.410 - Does each referral from an EN to a State VR agency require its own agreement?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Does each referral from an EN to a State VR agency require its own agreement? 411.410 Section 411.410 Employees' Benefits SOCIAL SECURITY...' Participation Agreements Between Employment Networks and State Vr Agencies § 411.410 Does each referral from...

  4. 31 CFR 256.13 - Are agencies required to supply a taxpayer identification number (TIN) when submitting a request...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... taxpayer identification number (TIN) when submitting a request for payment? 256.13 Section 256.13 Money and... BILLS Requesting Payments § 256.13 Are agencies required to supply a taxpayer identification number (TIN) when submitting a request for payment? Yes, agencies must include a valid TIN on all requests...

  5. 31 CFR 256.13 - Are agencies required to supply a taxpayer identification number (TIN) when submitting a request...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... taxpayer identification number (TIN) when submitting a request for payment? 256.13 Section 256.13 Money and... BILLS Requesting Payments § 256.13 Are agencies required to supply a taxpayer identification number (TIN) when submitting a request for payment? Yes, agencies must include a valid TIN on all requests...

  6. 31 CFR 256.13 - Are agencies required to supply a taxpayer identification number (TIN) when submitting a request...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... taxpayer identification number (TIN) when submitting a request for payment? 256.13 Section 256.13 Money and... BILLS Requesting Payments § 256.13 Are agencies required to supply a taxpayer identification number (TIN) when submitting a request for payment? Yes, agencies must include a valid TIN on all requests...

  7. 31 CFR 256.13 - Are agencies required to supply a taxpayer identification number (TIN) when submitting a request...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... taxpayer identification number (TIN) when submitting a request for payment? 256.13 Section 256.13 Money and... BILLS Requesting Payments § 256.13 Are agencies required to supply a taxpayer identification number (TIN) when submitting a request for payment? Yes, agencies must include a valid TIN on all requests...

  8. Alloy 800 specifications in compliance with component requirements

    NASA Astrophysics Data System (ADS)

    Diehl, H.; Bodmann, E.

    1990-04-01

    In view of the importance of the material Alloy 800 in high-temperature reactor plants (HTR), a material data bank was established which is used for statistical evaluation of mechanical and physical material behaviour. Based on investigations on the interconnection between the mechanical properties at high temperatures and the metallurgical parameters, different types of Alloy 800 were specified in compliance with the component requirements. In addition, aspects of corrosion and toughness behaviour were taken into consideration. The specifications and strength characteristics for the different variants of Alloy 800 were incorporated into draft DIN standards after discussion and approval in expert committees. Further important characteristics of the mechanical and physical material behaviour were summarized in HTR material data sheets so as to furnish an improved basis for the design and stress analyses of Alloy 800 components.

  9. CRISPR Immunological Memory Requires a Host Factor for Specificity.

    PubMed

    Nuñez, James K; Bai, Lawrence; Harrington, Lucas B; Hinder, Tracey L; Doudna, Jennifer A

    2016-06-16

    Bacteria and archaea employ adaptive immunity against foreign genetic elements using CRISPR-Cas systems. To generate immunological memory, the Cas1-Cas2 protein complex captures 30-40 base pair segments of foreign DNA and catalyzes their integration into the host genome as unique spacer sequences. Although spacers are inserted strictly at the A-T-rich leader end of CRISPR loci in vivo, the molecular mechanism of leader-specific spacer integration remains poorly understood. Here we show that the E. coli integration host factor (IHF) protein is required for spacer acquisition in vivo and for integration into linear DNA in vitro. IHF binds to the leader sequence and induces a sharp DNA bend, allowing the Cas1-Cas2 integrase to catalyze the first integration reaction at the leader-repeat border. Together, these results reveal that Cas1-Cas2-mediated spacer integration requires IHF-induced target DNA bending and explain the elusive role of CRISPR leader sequences during spacer acquisition.

  10. 36 CFR 1222.24 - How do agencies establish recordkeeping requirements?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF FEDERAL RECORDS Agency Recordkeeping... maintained for agency business through the scheduling process in part 1225 of this subchapter; (5....18; (7) Define the special recordkeeping responsibilities of program managers, information...

  11. 44 CFR 302.8 - Waiver of “single” State agency requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS CIVIL DEFENSE-STATE AND LOCAL EMERGENCY MANAGEMENT... agency (50 U.S.C. App. 2286). Notwithstanding such law, section 204 of the Intergovernmental...

  12. Program Requirements and Design Specifications for the Quincy School Complex.

    ERIC Educational Resources Information Center

    Quincy School Community Council, MA.

    The Quincy School Complex is a unique community facility. A high level of cooperation has led to the planning of this facility whose operation and ownership is divided among several agencies and groups. The introduction to the report on the school complex provides background material for the program itself, and attempts to define the "why" of the…

  13. 49 CFR 543.6 - Petition: Specific content requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...; (4) The reasons for the petitioner's belief that the antitheft device will be effective in reducing... petitioner and form a basis for that belief; (5) The reasons for the petitioner's belief that the agency... data that are available to the petitioner and form a basis for petitioner's belief that a line...

  14. Requirements for species-specific papovavirus DNA replication.

    PubMed Central

    Bennett, E R; Naujokas, M; Hassell, J A

    1989-01-01

    Replication of papovavirus DNA requires a functional replication origin, a virus-encoded protein, large T antigen, and species-specific permissive factors. How these components interact to initiate and sustain viral DNA replication is not known. Toward that end, we have attempted to identify the viral target(s) of permissive factors. The functionally defined replication origins of polyomavirus and simian virus 40, two papovaviruses that replicate in different species (mice and monkeys, respectively), are composed of two functionally distinct domains: a core domain and an auxiliary domain. The origin cores of the two viruses are remarkably similar in primary structure and have common binding sites for large T antigen. By contrast, their auxiliary domains share few sequences and serve as binding sites for cellular proteins. It seemed plausible, therefore, that if cellular permissive factors interacted with the replication origin, their targets were likely to be in the auxiliary domain. To test this hypothesis we constructed hybrid origins for DNA replication that were composed of the auxiliary domain of one virus and the origin core of the other and assessed their capacity to replicate in a number of mouse and monkey cell lines, which express the large T antigen of one or the other virus. The results of this analysis showed that the auxiliary domains of the viral replication origins could substitute for one another in DNA replication, provided that the viral origin core and its cognate large T antigen were present in a permissive cellular milieu. Surprisingly, the large T antigens of the viruses could not substitute for one another, regardless of the species of origin of the host cell, even though the two large T antigens bind to the same sequence motif in vitro. These results suggest that species-specific permissive factors do not interact with the origin-auxiliary domains but, rather, with either the origin core or the large T antigen or with both components to

  15. 41 CFR 102-83.110 - When an agency's mission and program requirements call for the location in an urban area, are...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... and program requirements call for the location in an urban area, are Executive agencies required to... REGULATION REAL PROPERTY 83-LOCATION OF SPACE Location of Space Urban Areas § 102-83.110 When an agency's mission and program requirements call for the location in an urban area, are Executive agencies...

  16. 48 CFR 306.302-1 - Only one responsible source and no other supplies or services will satisfy agency requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Only one responsible source and no other supplies or services will satisfy agency requirements. 306.302-1 Section 306.302-1 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and...

  17. 36 CFR 1234.22 - How does an agency request a waiver from a requirement in this part?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... September 28, 2005; and (3) The application of roof requirements in §§ 1234.10 and 1234.12 to underground... the information specified in paragraphs (c), (d), and/or (e) of this section to the Director, Space... for waiver of roof requirements for underground facility. The agency's waiver request must...

  18. 36 CFR 1234.22 - How does an agency request a waiver from a requirement in this part?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... September 28, 2005; and (3) The application of roof requirements in §§ 1234.10 and 1234.12 to underground... the information specified in paragraphs (c), (d), and/or (e) of this section to the Director, Space... for waiver of roof requirements for underground facility. The agency's waiver request must...

  19. Human factors requirements for telerobotic command and control: The European Space Agency experimental programme

    NASA Technical Reports Server (NTRS)

    Stone, Robert J.

    1991-01-01

    Space Telerobotics research, performed under contract to the European Space Agency (ESA), concerning the execution of human factors experiments, and ultimately leading to the development of a telerobotics test bed, has been carried out since 1985 by a British Consortium consisting of British Aerospace, the United Kingdom Atomic Energy Authority and, more recently, the UK National Advanced Robotics Research Centre. The principal aim of the first study of the series was to derive preliminary requirements for a teleoperation servicing system, with reference to two mission model scenarios. The first scenario introduced the problem of communications time delays, and their likely effect on the ground-based operator in control of a manipulator system on board an unmanned servicing vehicle in Low Earth Orbit. In the second scenario, the operator was located on the NASA Orbiter aft flight deck, supervising the control of a prototype manipulator in the 'servicing' of an experimental payload in the cargo bay area. Human factors analyses centered on defining the requirements for the teleoperator workstation, such as identifying basic ergonomic requirements for workstation and panel layouts, defining teleoperation strategies, developing alphanumeric and graphic screen formats for the supervision or direct control of the manipulator, and the potential applications of expert system technology. The second study for ESA involved an experimental appraisal of some of the important issues highlighted in the first study, for which relevant human factors data did not exist. Of central importance during the second study was the issue of communications time delays and their effect on the manual control of a teleoperated manipulator from a ground-based command and control station.

  20. Surveillance Analysis Computer System (SACS) software requirements specification (SRS)

    SciTech Connect

    Glasscock, J.A.; Flanagan, M.J.

    1995-09-01

    This document is the primary document establishing requirements for the Surveillance Analysis Computer System (SACS) Database, an Impact Level 3Q system. The purpose is to provide the customer and the performing organization with the requirements for the SACS Project.

  1. 41 CFR 102-83.120 - What happens if an agency has a need to be in a specific urban area that is not a central city in...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... agency has a need to be in a specific urban area that is not a central city in a metropolitan area? 102... is not a central city in a metropolitan area? If an agency has a need to be in a specific urban area that is not a central city in a metropolitan area, then the agency must give first consideration...

  2. 5 CFR 330.604 - Requirements for agency CTAP selection priority.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... REGULATIONS RECRUITMENT, SELECTION, AND PLACEMENT (GENERAL) Agency Career Transition Assistance Plan (CTAP...) Decisions involving discretionary areas under § 330.607 (such as whether excepted service employees...

  3. 5 CFR 330.604 - Requirements for agency CTAP selection priority.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... REGULATIONS RECRUITMENT, SELECTION, AND PLACEMENT (GENERAL) Agency Career Transition Assistance Plan (CTAP...) Decisions involving discretionary areas under § 330.607 (such as whether excepted service employees...

  4. 5 CFR 330.604 - Requirements for agency CTAP selection priority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... REGULATIONS RECRUITMENT, SELECTION, AND PLACEMENT (GENERAL) Agency Career Transition Assistance Plan (CTAP...) Decisions involving discretionary areas under § 330.607 (such as whether excepted service employees...

  5. 36 CFR 1222.24 - How do agencies establish recordkeeping requirements?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ....18; (7) Define the special recordkeeping responsibilities of program managers, information technology... RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF FEDERAL RECORDS Agency...

  6. 45 CFR 90.43 - What specific responsibilities do agencies and recipients have to ensure compliance with the Act?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... recipients have to ensure compliance with the Act? 90.43 Section 90.43 Public Welfare DEPARTMENT OF HEALTH....43 What specific responsibilities do agencies and recipients have to ensure compliance with the Act... written notice to each recipient of its obligations under the Act. The notice shall include a...

  7. 41 CFR 102-74.360 - What are the specific accident and fire prevention responsibilities of occupant agencies?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... accident and fire prevention responsibilities of occupant agencies? 102-74.360 Section 102-74.360 Public... MANAGEMENT REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Accident and Fire Prevention § 102-74.360 What are the specific accident and fire prevention responsibilities of occupant...

  8. 41 CFR 102-74.360 - What are the specific accident and fire prevention responsibilities of occupant agencies?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... accident and fire prevention responsibilities of occupant agencies? 102-74.360 Section 102-74.360 Public... MANAGEMENT REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Accident and Fire Prevention § 102-74.360 What are the specific accident and fire prevention responsibilities of occupant...

  9. 75 FR 12552 - Agency Information Collection Activities; Proposed Collection; Comment Request; Requirements...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-16

    ... HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities; Proposed... for public comment on the proposed collection of certain information by the agency. Under the... Register concerning each proposed collection of information and to allow 60 days for public comment...

  10. 78 FR 16678 - Agency Information Collection Activities; Proposed Collection; Comment Request; Requirements...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-18

    ... HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities; Proposed... 1986, as Amended by the Family Smoking Prevention and Tobacco Control Act AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing an...

  11. 5 CFR 250.101 - Standards and requirements for agency personnel actions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... personnel actions. 250.101 Section 250.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Authority for Personnel Actions in Agencies § 250.101... Personnel Management (OPM), the instructions OPM has published in the Guide to Processing Personnel...

  12. 5 CFR 250.101 - Standards and requirements for agency personnel actions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... personnel actions. 250.101 Section 250.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Authority for Personnel Actions in Agencies § 250.101... Personnel Management (OPM), the instructions OPM has published in the Guide to Processing Personnel...

  13. 5 CFR 250.101 - Standards and requirements for agency personnel actions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... personnel actions. 250.101 Section 250.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Authority for Personnel Actions in Agencies § 250.101... Personnel Management (OPM), the instructions OPM has published in the Guide to Processing Personnel...

  14. 5 CFR 250.101 - Standards and requirements for agency personnel actions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... personnel actions. 250.101 Section 250.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Authority for Personnel Actions in Agencies § 250.101... Personnel Management (OPM), the instructions OPM has published in the Guide to Processing Personnel...

  15. 5 CFR 250.101 - Standards and requirements for agency personnel actions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... personnel actions. 250.101 Section 250.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Authority for Personnel Actions in Agencies § 250.101... Personnel Management (OPM), the instructions OPM has published in the Guide to Processing Personnel...

  16. 49 CFR 179.401-1 - Individual specification requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS SPECIFICATIONS... specification 113A60W 113C120W Design service temperature, °F −423 −260. Material § 179.400-5 § 179.400-5. Impact test (weld and plate material) § 179.400-5(c) § 179.400-5(c). Impact test values §...

  17. Actin isoform specificity is required for the maintenance of lactation

    PubMed Central

    Weymouth, Nate; Shi, Zengdun; Rockey, Don C.

    2014-01-01

    Smooth muscle α-actin (Acta2) is one of six highly conserved mammalian actin isoforms that appear to exhibit functional redundancy. Nonetheless, we have postulated a specific functional role for the smooth muscle specific isoform. Here, we show that Acta2 deficient mice have a remarkable mammary phenotype such that dams lacking Acta2 are unable to nurse their offspring effectively. The phenotype was rescued in cross fostering experiments with wild type mice, excluding a developmental defect in Acta2 null pups. The mechanism for the underlying phenotype is due to myoepithelial dysfunction postpartum resulting in precocious involution. Further, we demonstrate a specific defect in myoepithelial cell contractility in Acta2 null mammary glands, despite normal expression of cytoplasmic actins. We conclude that Acta2 specifically mediates myoepithelial cell contraction during lactation and that this actin isoform therefore exhibits functional specificity. PMID:22123032

  18. 29 CFR 1926.452 - Additional requirements applicable to specific types of scaffolds.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 8 2012-07-01 2012-07-01 false Additional requirements applicable to specific types of... Scaffolds § 1926.452 Additional requirements applicable to specific types of scaffolds. In addition to the applicable requirements of § 1926.451, the following requirements apply to the specific types of...

  19. 29 CFR 1926.452 - Additional requirements applicable to specific types of scaffolds.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 8 2011-07-01 2011-07-01 false Additional requirements applicable to specific types of... Scaffolds § 1926.452 Additional requirements applicable to specific types of scaffolds. In addition to the applicable requirements of § 1926.451, the following requirements apply to the specific types of...

  20. 29 CFR 1926.452 - Additional requirements applicable to specific types of scaffolds.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 8 2013-07-01 2013-07-01 false Additional requirements applicable to specific types of... Scaffolds § 1926.452 Additional requirements applicable to specific types of scaffolds. In addition to the applicable requirements of § 1926.451, the following requirements apply to the specific types of...

  1. 29 CFR 1926.452 - Additional requirements applicable to specific types of scaffolds.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 8 2014-07-01 2014-07-01 false Additional requirements applicable to specific types of... Scaffolds § 1926.452 Additional requirements applicable to specific types of scaffolds. In addition to the applicable requirements of § 1926.451, the following requirements apply to the specific types of...

  2. Analyzing Tabular Requirements Specifications Using Infinite State Model Checking

    DTIC Science & Technology

    2006-01-01

    two-state properties that hold in every reachable transition. Property Checking with Salsa . The SCR property checker Salsa [5] may be used to check...SCR specifications for Dis- jointness and Coverage and for satisfaction of state and tran- sition invariants. Salsa can check the validity of formulas...TAME and Salsa . 3. Action Language Verifier Action Language is a specification language for reactive software systems. The Action Language Verifier

  3. SWEPP assay system version 2.0 software requirements specification

    SciTech Connect

    Matthews, S.D.; East, L.V.; Marwil, E.S.; Ferguson, J.J.

    1996-06-01

    The INEL Stored Waste Examination Pilot Plant (SWEPP) operations staff use nondestructive analysis methods to characterize the radiological contents of contact-handled radioactive waste containers. Containers of waste from Rocky Flats Environmental Technology Site and other DOE sites are currently stored at SWEPP. Before these containers can be shipped to WIPP, SWEPP must verify compliance with storage, shipping, and disposal requirements. One part of the SWEPP program measures neutron emissions from the containers and estimates the mass of Pu and other transuranic isotopes present. The code NEUT2 was originally used to perform data acquisition and reduction; the SWEPP Assay System (SAS) code replaced NEUT2 in early 1994. This document specifies the requirements for the SAS software as installed at INEL and was written to comply with RWMC (INEL Radioactive Waste Management Complex) quality requirements.

  4. 41 CFR 102-83.35 - Are Executive agencies required to consider whether the central business area will provide for...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... required to consider whether the central business area will provide for adequate competition when acquiring... central business area will provide for adequate competition when acquiring leased space? In accordance with the Competition in Contracting Act of 1984, as amended (41 U.S.C. 253(a)), Executive agencies...

  5. 18 CFR 401.39 - Form of submission of projects not requiring prior approval by State or Federal agencies.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Form of submission of projects not requiring prior approval by State or Federal agencies. 401.39 Section 401.39 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE...

  6. 41 CFR 102-74.200 - What information are Federal agencies required to report to the Department of Energy (DOE)?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... DOE Federal Energy Usage Report DOE F 6200.2 Instructions. Ridesharing ... Federal agencies required to report to the Department of Energy (DOE)? 102-74.200 Section 102-74.200...) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Energy...

  7. 41 CFR 102-74.200 - What information are Federal agencies required to report to the Department of Energy (DOE)?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... DOE Federal Energy Usage Report DOE F 6200.2 Instructions. Ridesharing ... Federal agencies required to report to the Department of Energy (DOE)? 102-74.200 Section 102-74.200...) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Energy...

  8. 41 CFR 102-74.200 - What information are Federal agencies required to report to the Department of Energy (DOE)?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... DOE Federal Energy Usage Report DOE F 6200.2 Instructions. Ridesharing ... Federal agencies required to report to the Department of Energy (DOE)? 102-74.200 Section 102-74.200...) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Energy...

  9. 41 CFR 102-74.200 - What information are Federal agencies required to report to the Department of Energy (DOE)?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... DOE Federal Energy Usage Report DOE F 6200.2 Instructions. Ridesharing ... Federal agencies required to report to the Department of Energy (DOE)? 102-74.200 Section 102-74.200...) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Energy...

  10. 41 CFR 102-74.200 - What information are Federal agencies required to report to the Department of Energy (DOE)?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... DOE Federal Energy Usage Report DOE F 6200.2 Instructions. Ridesharing ... Federal agencies required to report to the Department of Energy (DOE)? 102-74.200 Section 102-74.200...) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Energy...

  11. 34 CFR 222.63 - What other requirements must a local educational agency meet in order to be eligible for...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... meet in order to be eligible for financial assistance under section 8003(f)(2)(A)? 222.63 Section 222... Local Educational Agencies Under Section 8003(f) of the Act § 222.63 What other requirements must a...)(A)? Subject to § 222.65, an LEA described in § 222.62(a), (b), or (c) is eligible for...

  12. 34 CFR 222.64 - What other requirements must a local educational agency meet in order to be eligible for...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... meet in order to be eligible for financial assistance under section 8003(f)(2)(B)? 222.64 Section 222... Local Educational Agencies Under Section 8003(f) of the Act § 222.64 What other requirements must a...)(B)? Subject to § 222.65, an LEA described in § 222.62(d) is eligible for financial assistance...

  13. Requirements for Minimum Sample Size for Sensitivity and Specificity Analysis

    PubMed Central

    Adnan, Tassha Hilda

    2016-01-01

    Sensitivity and specificity analysis is commonly used for screening and diagnostic tests. The main issue researchers face is to determine the sufficient sample sizes that are related with screening and diagnostic studies. Although the formula for sample size calculation is available but concerning majority of the researchers are not mathematicians or statisticians, hence, sample size calculation might not be easy for them. This review paper provides sample size tables with regards to sensitivity and specificity analysis. These tables were derived from formulation of sensitivity and specificity test using Power Analysis and Sample Size (PASS) software based on desired type I error, power and effect size. The approaches on how to use the tables were also discussed. PMID:27891446

  14. 78 FR 10685 - Reports, Forms, and Recordkeeping Requirements: Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-14

    ... (TPMS) were ] mandated in Federal Motor Vehicle Safety Standard (FMVSS) No. 138, so that drivers are... vehicles with TPMS in comparison to vehicles of the same age without TPMS. Survey results led the agency...

  15. 77 FR 26068 - Reports, Forms and Record Keeping Requirements; Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-02

    ... Doc No: 2012-10566] DEPARTMENT OF TRANSPORTATION National Highway Traffic Safety Administration... AGENCY: National Highway Traffic Safety Administration (NHTSA), U.S. Department of Transportation (DOT... Highway Traffic Safety Administration Title: 49 CFR 575--Consumer Information Regulations (sections...

  16. 76 FR 22450 - Agency Information Collection Activities; Proposed Information Collection Requirements; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-21

    ... should be addressed to: OCC: Communications Division, Office of the Comptroller of the Currency, Mailstop... 20503 or by facsimile to 202-395-6974, Attention: Federal Banking Agency Desk Officer. FOR...

  17. 30 CFR 23.7 - Specific requirements for approval.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... reserves the right to require the attachment of wiring diagrams to the cases of telephones and signal..., the electrical design and construction of telephones and signal devices shall be such that neither... external terminals and circuits will result in electrical sparks capable of igniting explosive...

  18. System requirements specification for waste information and control system

    SciTech Connect

    Harris, R.R.

    1994-09-01

    This document defines the requirements for the Waste Information and Control System (WICS). The document defines the functions, constraints, and objectives that pertain to WICS. This shall serve as the baseline document to ensure the needs of the Hazardous Material Control group (HMC) at 222-S Laboratory are met with regard to assurance of accuracy and quality of data taken with WICS.

  19. 40 CFR 86.1406 - Equipment required and specifications; overview.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... described in § 86.1439(d). When a CST employs transient loaded warmup operation or loaded preconditioning... and 85.2233 of this chapter. (2) Exhaust gas analysis system. (i) The requirements for the exhaust gas analysis system are set forth in §§ 85.2225 and 85.2233 of this chapter, except that the NO channel...

  20. Losing Something In Translation: Turning Requirements Into Specifications

    DTIC Science & Technology

    2016-06-01

    managers develop the operational Affordability Allocated Analysis Bureaucratic Capability Compliance Contractual Cost Customer Data Derived Design...Requirements Center Director at the Defense Acquisition University’s Defense Systems Management College at Fort Belvoir in Virginia. He is a former Wild...Weasel Electronic Warfare Officer, a test manager , a program manager , and an Air Force laboratory supervisor. His doctorate from Walden University

  1. An Operational Approach to Requirements Specification for Embedded Systems.

    DTIC Science & Technology

    1981-08-01

    language can have is to be unable to express what the requirements analyst wants to say. This is the problem that makes analysts revert to English ...APPENDIX: A GRAMMAR FOR PAISLEY This gramar is LALR, and is written in BNF with nonterminals underlined. Comments are transparent, and can therefore

  2. 49 CFR 179.101-1 - Individual specification requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120... thickness of plates shall be not less than 1/2 inch. 4 Tank cars not equipped with a thermal protection or an insulation system used for the transportation of a Class 2 (compressed gas) material must have...

  3. 49 CFR 180.209 - Requirements for requalification of specification cylinders.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ....209 Requirements for requalification of specification cylinders. (a) Periodic qualification of cylinders. Each specification cylinder that becomes due for periodic requalification, as specified in the following table, must be requalified and marked in conformance with the requirements of this...

  4. 75 FR 36067 - Agency Information Collection Activities; Proposed Collection; Comment Request; Chemical-Specific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-24

    ... Rules, TSCA Section 8(a); EPA ICR No. 1198.09, OMB Control No. 2070-0067 AGENCY: Environmental....S.C. 3501 et seq.), this document announces that EPA is planning to submit a request to renew an... and OMB Control No. 2070-0067, is scheduled to expire on January 31, 2011. Before submitting the...

  5. 14 CFR 417.17 - Launch reporting requirements and launch specific updates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... specific updates. 417.17 Section 417.17 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL... Conditions § 417.17 Launch reporting requirements and launch specific updates. (a) General. A launch operator must satisfy the launch reporting requirements and launch specific updates required by this section...

  6. End User Acceptance - Requirements or Specifications, Certification, Testing

    NASA Technical Reports Server (NTRS)

    Jeevarajan, Judith

    2013-01-01

    NASA follows top level safety requirement of two-failure tolerance (t hree levels of controls or design for minimum risk) to all catastroph ic hazards in the design of safe li-ion batteries for space use. ? R igorous development testing at appropriate levels to credible offnominal conditions and review of test data. ? Implement robust design con trols based on test results and test again to confirm safety at the a ppropriate levels. ? Stringent testing of all (100%) flight batteries (from button cells to large batteries).

  7. Software requirements specification document for the AREST code development

    SciTech Connect

    Engel, D.W.; McGrail, B.P.; Whitney, P.D.; Gray, W.J.; Williford, R.E.; White, M.D.; Eslinger, P.W.; Altenhofen, M.K.

    1993-11-01

    The Analysis of the Repository Source Term (AREST) computer code was selected in 1992 by the U.S. Department of Energy. The AREST code will be used to analyze the performance of an underground high level nuclear waste repository. The AREST code is being modified by the Pacific Northwest Laboratory (PNL) in order to evaluate the engineered barrier and waste package designs, model regulatory compliance, analyze sensitivities, and support total systems performance assessment modeling. The current version of the AREST code was developed to be a very useful tool for analyzing model uncertainties and sensitivities to input parameters. The code has also been used successfully in supplying source-terms that were used in a total systems performance assessment. The current version, however, has been found to be inadequate for the comparison and selection of a design for the waste package. This is due to the assumptions and simplifications made in the selection of the process and system models. Thus, the new version of the AREST code will be designed to focus on the details of the individual processes and implementation of more realistic models. This document describes the requirements of the new models that will be implemented. Included in this document is a section describing the near-field environmental conditions for this waste package modeling, description of the new process models that will be implemented, and a description of the computer requirements for the new version of the AREST code.

  8. HSCT4.0 Application: Software Requirements Specification

    NASA Technical Reports Server (NTRS)

    Salas, A. O.; Walsh, J. L.; Mason, B. H.; Weston, R. P.; Townsend, J. C.; Samareh, J. A.; Green, L. L.

    2001-01-01

    The software requirements for the High Performance Computing and Communication Program High Speed Civil Transport application project, referred to as HSCT4.0, are described. The objective of the HSCT4.0 application project is to demonstrate the application of high-performance computing techniques to the problem of multidisciplinary design optimization of a supersonic transport configuration, using high-fidelity analysis simulations. Descriptions of the various functions (and the relationships among them) that make up the multidisciplinary application as well as the constraints on the software design arc provided. This document serves to establish an agreement between the suppliers and the customer as to what the HSCT4.0 application should do and provides to the software developers the information necessary to design and implement the system.

  9. Are patient specific meshes required for EIT head imaging?

    PubMed

    Jehl, Markus; Aristovich, Kirill; Faulkner, Mayo; Holder, David

    2016-06-01

    Head imaging with electrical impedance tomography (EIT) is usually done with time-differential measurements, to reduce time-invariant modelling errors. Previous research suggested that more accurate head models improved image quality, but no thorough analysis has been done on the required accuracy. We propose a novel pipeline for creation of precise head meshes from magnetic resonance imaging and computed tomography scans, which was applied to four different heads. Voltages were simulated on all four heads for perturbations of different magnitude, haemorrhage and ischaemia, in five different positions and for three levels of instrumentation noise. Statistical analysis showed that reconstructions on the correct mesh were on average 25% better than on the other meshes. However, the stroke detection rates were not improved. We conclude that a generic head mesh is sufficient for monitoring patients for secondary strokes following head trauma.

  10. Specification of advanced safety modeling requirements (Rev. 0).

    SciTech Connect

    Fanning, T. H.; Tautges, T. J.

    2008-06-30

    The U.S. Department of Energy's Global Nuclear Energy Partnership has lead to renewed interest in liquid-metal-cooled fast reactors for the purpose of closing the nuclear fuel cycle and making more efficient use of future repository capacity. However, the U.S. has not designed or constructed a fast reactor in nearly 30 years. Accurate, high-fidelity, whole-plant dynamics safety simulations will play a crucial role by providing confidence that component and system designs will satisfy established design limits and safety margins under a wide variety of operational, design basis, and beyond design basis transient conditions. Current modeling capabilities for fast reactor safety analyses have resulted from several hundred person-years of code development effort supported by experimental validation. The broad spectrum of mechanistic and phenomenological models that have been developed represent an enormous amount of institutional knowledge that needs to be maintained. Complicating this, the existing code architectures for safety modeling evolved from programming practices of the 1970s. This has lead to monolithic applications with interdependent data models which require significant knowledge of the complexities of the entire code in order for each component to be maintained. In order to develop an advanced fast reactor safety modeling capability, the limitations of the existing code architecture must be overcome while preserving the capabilities that already exist. To accomplish this, a set of advanced safety modeling requirements is defined, based on modern programming practices, that focuses on modular development within a flexible coupling framework. An approach for integrating the existing capabilities of the SAS4A/SASSYS-1 fast reactor safety analysis code into the SHARP framework is provided in order to preserve existing capabilities while providing a smooth transition to advanced modeling capabilities. In doing this, the advanced fast reactor safety models will

  11. 78 FR 32392 - Agency Information Collection Activities; Proposed Collection; Comment Request; Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-30

    ... information by July 29, 2013. ADDRESSES: Submit electronic comments on the collection of information to http.... The digital certificate binds together the owner's name and a pair of electronic keys (a public key... HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities;...

  12. 42 CFR 488.68 - State Agency responsibilities for OASIS collection and data base requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... operating the OASIS system: (a) Establish and maintain an OASIS database. The State agency or other entity... data; (2) Conduct basic system management activities including hardware and software maintenance, system back-up, and monitoring the status of the database; and (3) Obtain CMS approval before...

  13. 42 CFR 488.68 - State Agency responsibilities for OASIS collection and data base requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... operating the OASIS system: (a) Establish and maintain an OASIS database. The State agency or other entity... data; (2) Conduct basic system management activities including hardware and software maintenance, system back-up, and monitoring the status of the database; and (3) Obtain CMS approval before...

  14. 42 CFR 488.68 - State Agency responsibilities for OASIS collection and data base requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... operating the OASIS system: (a) Establish and maintain an OASIS database. The State agency or other entity... data; (2) Conduct basic system management activities including hardware and software maintenance, system back-up, and monitoring the status of the database; and (3) Obtain CMS approval before...

  15. 42 CFR 488.68 - State Agency responsibilities for OASIS collection and data base requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... operating the OASIS system: (a) Establish and maintain an OASIS database. The State agency or other entity... data; (2) Conduct basic system management activities including hardware and software maintenance, system back-up, and monitoring the status of the database; and (3) Obtain CMS approval before...

  16. 7 CFR 245.12 - State agencies and direct certification requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS DETERMINING ELIGIBILITY FOR FREE AND... performance benchmarks set forth in paragraph (b) of this section for directly certifying children who are.... State agencies must meet performance benchmarks for directly certifying for free school meals...

  17. 76 FR 38457 - Reports, Forms and Record Keeping Requirements Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-30

    ...: Replaceable Light Source Information Collection, 49 CFR part 564. OMB Number: 2127-0506. Type of Request... agency issued FMVSS no. 125, ``Warning Devices'', which applies to devices, without self contained energy sources, that are designed to be carried mandatory in buses and trucks that have a gross vehicle...

  18. 78 FR 73104 - Federal Travel Regulation (FTR); Agency Requirements for Payment of Expenses Connected With the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-05

    ... With the Death of Certain Employees and Family Members AGENCY: Office of Governmentwide Policy, U.S... death of certain employees and family members. This final rule establishes policy and procedures for relocation of dependents and household goods of an employee whose death occurred while away from the...

  19. 76 FR 58493 - Agency Information Collection Activities; Proposed Collection; Comment Request; Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-21

    ... Generators, Transporters, and Waste Management Facilities Under the RCRA Hazardous Waste Manifest System... (28221T), U.S. Environmental Protection Agency, 1200 Pennsylvania Avenue, NW., Washington, DC 20460. Hand Delivery: 1301 Constitution Ave., NW., Room 3334, Washington, DC 20460. Such deliveries are only...

  20. Solar powered biohydrogen production requires specific localization of the hydrogenase

    SciTech Connect

    Burroughs, Nigel J.; Boehm, Marko; Eckert, Carrie; Mastroianni, Giulia; Spence, Edward M.; Yu, Jianfeng; Nixon, Peter J.; Appel, Jens; Mullineaux, Conrad W.; Bryan, Samantha J.

    2014-09-04

    Cyanobacteria contain a bidirectional [NiFe] hydrogenase which transiently produces hydrogen upon exposure of anoxic cells to light, potentially acting as a “valve” releasing excess electrons from the electron transport chain. However, its interaction with the photosynthetic electron transport chain remains unclear. By GFP-tagging the HoxF diaphorase subunit we show that the hydrogenase is thylakoid associated, comprising a population dispersed uniformly through the thylakoids and a subpopulation localized to discrete puncta in the distal thylakoid. Thylakoid localisation of both the HoxH and HoxY hydrogenase subunits is confirmed by immunogold electron microscopy. The diaphorase HoxE subunit is essential for recruitment to the dispersed thylakoid population, potentially anchoring the hydrogenase to the membrane, but aggregation to puncta occurs through a distinct HoxE-independent mechanism. Membrane association does not require NDH-1. Localization is dynamic on a scale of minutes, with anoxia and high light inducing a significant redistribution between these populations in favour of puncta. Lastly, since HoxE is essential for access to its electron donor, electron supply to the hydrogenase depends on a physiologically controlled localization, potentially offering a new avenue to enhance photosynthetic hydrogen production by exploiting localization/aggregation signals.

  1. Search Hanford accessible reports electronically system requirements specification

    SciTech Connect

    Willers, K.J.

    1994-02-28

    The Emergency, Safety, & Quality (ESQ) Services organization of Westinghouse Hanford Company (WHC) is experiencing changes related to new programs. The programs include Corrective Actions Management Systems, Self-Assessment, Trend Analysis, and Lessons Learned analysis. The programs are pushing up organizational costs while funding and manpower levels are projected to be dropping. A large cost involved in implementing the new programs is the cost for people to locate unstructured information required to make decisions or write documentation. But, most resources for retrieving information are found in structured database systems. This means that unstructured information that must be located has to be found by one of these methods: (1) searching manually through documents, (2) searching individual documents one at a time with word processing programs, (3) searching through text fields with query systems primarily designed for structured database information, or (4) develop a text search and retrieval system designed for unstructured information. One example of this is using Occurrence Reporting Processing System (ORPS) and Quality, Environmental, and Safety Tracking (QUEST) documents. An explanation of this is in the following textual box.

  2. Solar powered biohydrogen production requires specific localization of the hydrogenase

    DOE PAGES

    Burroughs, Nigel J.; Boehm, Marko; Eckert, Carrie; ...

    2014-09-04

    Cyanobacteria contain a bidirectional [NiFe] hydrogenase which transiently produces hydrogen upon exposure of anoxic cells to light, potentially acting as a “valve” releasing excess electrons from the electron transport chain. However, its interaction with the photosynthetic electron transport chain remains unclear. By GFP-tagging the HoxF diaphorase subunit we show that the hydrogenase is thylakoid associated, comprising a population dispersed uniformly through the thylakoids and a subpopulation localized to discrete puncta in the distal thylakoid. Thylakoid localisation of both the HoxH and HoxY hydrogenase subunits is confirmed by immunogold electron microscopy. The diaphorase HoxE subunit is essential for recruitment to themore » dispersed thylakoid population, potentially anchoring the hydrogenase to the membrane, but aggregation to puncta occurs through a distinct HoxE-independent mechanism. Membrane association does not require NDH-1. Localization is dynamic on a scale of minutes, with anoxia and high light inducing a significant redistribution between these populations in favour of puncta. Lastly, since HoxE is essential for access to its electron donor, electron supply to the hydrogenase depends on a physiologically controlled localization, potentially offering a new avenue to enhance photosynthetic hydrogen production by exploiting localization/aggregation signals.« less

  3. Robust Entrainment of Circadian Oscillators Requires Specific Phase Response Curves

    PubMed Central

    Pfeuty, Benjamin; Thommen, Quentin; Lefranc, Marc

    2011-01-01

    The circadian clocks keeping time in many living organisms rely on self-sustained biochemical oscillations entrained by external cues, such as light, to the 24-h cycle induced by Earth's rotation. However, environmental cues are unreliable due to the variability of habitats, weather conditions, or cue-sensing mechanisms among individuals. A tempting hypothesis is that circadian clocks have evolved so as to be robust to fluctuations in the signal that entrains them. To support this hypothesis, we analyze the synchronization behavior of weakly and periodically forced oscillators in terms of their phase response curve (PRC), which measures phase changes induced by a perturbation applied at different times of the cycle. We establish a general relationship between the robustness of key entrainment properties, such as stability and oscillator phase, on the one hand, and the shape of the PRC as characterized by a specific curvature or the existence of a dead zone, on the other hand. The criteria obtained are applied to computational models of circadian clocks and account for the disparate robustness properties of various forcing schemes. Finally, the analysis of PRCs measured experimentally in several organisms strongly suggests a case of convergent evolution toward an optimal strategy for maintaining a clock that is accurate and robust to environmental fluctuations. PMID:21641300

  4. Specific requirement for CD3ɛ in T cell development

    PubMed Central

    DeJarnette, Jan B.; Sommers, Connie L.; Huang, Kun; Woodside, Kenneth J.; Emmons, Rebecca; Katz, Kenneth; Shores, Elizabeth W.; Love, Paul E.

    1998-01-01

    T cell antigen receptor (TCR) and pre-TCR complexes are composed of clonotypic heterodimers in association with dimers of signal transducing invariant subunits (CD3γ, -δ, -ɛ, and ζ). The role of individual invariant subunits in T cell development has been investigated by generating gene-specific mutations in mice. Mutation of CD3γ, -δ, or ζ results in an incomplete block in development, characterized by reduced numbers of mature T cells that express low levels of TCR. In contrast, mature T cells are absent from CD3ɛ−/− mice, and thymocyte development is arrested at the early CD4−CD8− stage. Although these results suggest that CD3ɛ is essential for pre-TCR and TCR expression/function, their interpretation is complicated by the fact that expression of the CD3γ and CD3δ genes also is reduced in CD3ɛ−/− mice. Thus, it is unclear whether the phenotype of CD3ɛ−/− mice reflects the collective effects of CD3γ, -δ, and -ɛ deficiency. By removing the selectable marker (PGK-NEO) from the targeted CD3ɛ gene via Cre/loxP-mediated recombination, we generated mice that lack CD3ɛ yet retain normal expression of the closely linked CD3γ and CD3δ genes. These (CD3ɛΔ/Δ) mice exhibited an early arrest in T cell development, similar to that of CD3ɛ−/− mice. Moreover, the developmental defect could be rescued by expression of a CD3ɛ transgene. These results identify an essential role for CD3ɛ in T cell development not shared by the CD3γ, CD3δ, or ζ-family proteins and provide further evidence that PGK-NEO can influence the expression of genes in its proximity. PMID:9843989

  5. 40 CFR 60.2910 - What site-specific documentation is required?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... required? 60.2910 Section 60.2910 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Solid Waste Incineration Units for Which Construction is Commenced After December 9, 2004, or for Which... and readily accessible for all OSWI unit operators that addresses the nine topics described...

  6. 40 CFR 60.2095 - What site-specific documentation is required?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... required? 60.2095 Section 60.2095 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Commercial and Industrial Solid Waste Incineration Units for Which Construction Is Commenced After November... be available at the facility and readily accessible for all CISWI unit operators that addresses...

  7. 40 CFR 60.2095 - What site-specific documentation is required?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... required? 60.2095 Section 60.2095 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Commercial and Industrial Solid Waste Incineration Units for Which Construction Is Commenced After November... be available at the facility and readily accessible for all CISWI unit operators that addresses...

  8. 40 CFR 60.2095 - What site-specific documentation is required?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... required? 60.2095 Section 60.2095 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Commercial and Industrial Solid Waste Incineration Units Operator Training and Qualification § 60.2095 What... readily accessible for all CISWI unit operators that addresses the ten topics described in paragraphs...

  9. 40 CFR 60.2910 - What site-specific documentation is required?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... required? 60.2910 Section 60.2910 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... facility and readily accessible for all OSWI unit operators that addresses the nine topics described in...) Procedures for receiving, handling, and charging waste. (3) Incinerator startup, shutdown, and...

  10. 40 CFR 60.3019 - What site-specific documentation is required?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... required? 60.3019 Section 60.3019 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Times for Other Solid Waste Incineration Units That Commenced Construction On or Before December 9, 2004...? (a) Documentation must be available at the facility and readily accessible for all OSWI...

  11. 40 CFR 60.2660 - What site-specific documentation is required?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... required? 60.2660 Section 60.2660 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Compliance Times for Commercial and Industrial Solid Waste Incineration Units that Commenced Construction On... accessible for all CISWI unit operators that addresses the ten topics described in paragraphs (a)(1)...

  12. 40 CFR 60.2660 - What site-specific documentation is required?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... required? 60.2660 Section 60.2660 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Operator Training... available at the facility and readily accessible for all CISWI unit operators that addresses the ten...

  13. 40 CFR 60.3019 - What site-specific documentation is required?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... required? 60.3019 Section 60.3019 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Times for Other Solid Waste Incineration Units That Commenced Construction On or Before December 9, 2004...? (a) Documentation must be available at the facility and readily accessible for all OSWI...

  14. 40 CFR 60.2660 - What site-specific documentation is required?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... required? 60.2660 Section 60.2660 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Operator Training... available at the facility and readily accessible for all CISWI unit operators that addresses the ten...

  15. 40 CFR 60.2910 - What site-specific documentation is required?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... required? 60.2910 Section 60.2910 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... facility and readily accessible for all OSWI unit operators that addresses the nine topics described in...) Procedures for receiving, handling, and charging waste. (3) Incinerator startup, shutdown, and...

  16. 40 CFR 60.2660 - What site-specific documentation is required?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... required? 60.2660 Section 60.2660 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Operator Training... available at the facility and readily accessible for all CISWI unit operators that addresses the ten...

  17. 40 CFR 60.2910 - What site-specific documentation is required?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... required? 60.2910 Section 60.2910 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Solid Waste Incineration Units for Which Construction is Commenced After December 9, 2004, or for Which... and readily accessible for all OSWI unit operators that addresses the nine topics described...

  18. 40 CFR 60.3019 - What site-specific documentation is required?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... required? 60.3019 Section 60.3019 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Times for Other Solid Waste Incineration Units That Commenced Construction On or Before December 9, 2004...? (a) Documentation must be available at the facility and readily accessible for all OSWI...

  19. 40 CFR 60.3019 - What site-specific documentation is required?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... required? 60.3019 Section 60.3019 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Times for Other Solid Waste Incineration Units That Commenced Construction On or Before December 9, 2004...? (a) Documentation must be available at the facility and readily accessible for all OSWI...

  20. 46 CFR 62.35-50 - Tabulated monitoring and safety control requirements for specific systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Tabulated monitoring and safety control requirements for... Systems § 62.35-50 Tabulated monitoring and safety control requirements for specific systems. The minimum instrumentation, alarms, and safety controls required for specific types of systems are listed in Table...

  1. 46 CFR 91.55-5 - Plans and specifications required for new construction.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Plans and specifications required for new construction... MISCELLANEOUS VESSELS INSPECTION AND CERTIFICATION Plan Approval § 91.55-5 Plans and specifications required for new construction. (a) General. (1) Specifications. (2) General Arrangement Plan of decks, holds,...

  2. 46 CFR 91.55-5 - Plans and specifications required for new construction.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Plans and specifications required for new construction... MISCELLANEOUS VESSELS INSPECTION AND CERTIFICATION Plan Approval § 91.55-5 Plans and specifications required for new construction. (a) General. (1) Specifications. (2) General Arrangement Plan of decks, holds,...

  3. 46 CFR 91.55-5 - Plans and specifications required for new construction.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Plans and specifications required for new construction... MISCELLANEOUS VESSELS INSPECTION AND CERTIFICATION Plan Approval § 91.55-5 Plans and specifications required for new construction. (a) General. (1) Specifications. (2) General Arrangement Plan of decks, holds,...

  4. 41 CFR 301-50.4 - May I be granted an exception to the required use of TMS or ETS once my agency has fully deployed...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... exception to the required use of TMS or ETS once my agency has fully deployed ETS? 301-50.4 Section 301-50.4... TRAVEL SERVICES § 301-50.4 May I be granted an exception to the required use of TMS or ETS once my agency has fully deployed ETS? Yes, your agency head or his/her designee may grant an individual...

  5. 77 FR 47914 - Reports, Forms and Recordkeeping Requirements Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-10

    ... collection of information described is the ``Roof Crush Resistance Phase in Reporting Requirements--Part 585... Traffic Safety Administration Title: Roof Crush Resistance Phase in Reporting Requirements--Part 585. OMB... requirements of FMVSS No. 216, ``Roof crush resistance.'' The final rule contained a collection of...

  6. 34 CFR 222.52 - What requirements must a local educational agency meet to receive a payment under section 8003(d)?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 1 2012-07-01 2012-07-01 false What requirements must a local educational agency meet to receive a payment under section 8003(d)? 222.52 Section 222.52 Education Regulations of the... Serve Children With Disabilities § 222.52 What requirements must a local educational agency meet...

  7. Using SCOR as a Supply Chain Management Framework for Government Agency Contract Requirements

    NASA Technical Reports Server (NTRS)

    Paxton, Joe

    2010-01-01

    Enterprise Supply Chain Management consists of: Specifying suppliers to support inter-program and inter-agency efforts. Optimizing inventory levels and locations throughout the supply chain. Executing corrective actions to improve quality and lead time issues throughout the supply chain. Processing reported data to calculate and make visible supply chain performance (provide information for decisions and actions). Ensuring the right hardware and information is provided at the right time and in the right place. Monitoring the industrial base while developing, producing, operating and retiring a system. Seeing performance deep in the supply chain that could indicate issues affecting system availability and readiness.

  8. Reference manual for a Requirements Specification Language (RSL), version 2.0

    NASA Technical Reports Server (NTRS)

    Fisher, Gene L.; Cohen, Gerald C.

    1993-01-01

    This report is a Reference Manual for a general-purpose Requirements Specification Language, RSL. The purpose of RSL is to specify precisely the external structure of a mechanized system and to define requirements that the system must meet. A system can be comprised of a mixture of hardware, software, and human processing elements. RSL is a hybrid of features found in several popular requirements specification languages and includes constructs for formal mathematical specification.

  9. 24 CFR 200.936 - Supplementary specific procedural requirements under HUD building products certification program...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... requirements under HUD building products certification program for solid fuel type room heaters and fireplace... Supplementary specific procedural requirements under HUD building products certification program for solid fuel... fireplace stoves certified under the HUD Building Products Certification Program shall be...

  10. 24 CFR 200.936 - Supplementary specific procedural requirements under HUD building products certification program...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... requirements under HUD building products certification program for solid fuel type room heaters and fireplace... Supplementary specific procedural requirements under HUD building products certification program for solid fuel... fireplace stoves certified under the HUD Building Products Certification Program shall be...

  11. Brain-specific-homeobox is required for the specification of neuronal types in the Drosophila optic lobe.

    PubMed

    Hasegawa, Eri; Kaido, Masako; Takayama, Rie; Sato, Makoto

    2013-05-01

    The Drosophila optic lobe comprises a wide variety of neurons forming laminar and columnar structures similar to the mammalian brain. The Drosophila optic lobe may provide an excellent model to investigate various processes of brain development. However, it is poorly understood how neuronal specification is regulated in the optic lobe to form a complicated structure. Here we show that the Brain-specific-homeobox (Bsh) protein, which is expressed in the lamina and medulla ganglia, is involved in specifying neuronal identity. Bsh is expressed in L4 and L5 lamina neurons and in Mi1 medulla neurons. Analyses of loss-of-function and gain-of-function clones suggest that Bsh is required and largely sufficient for Mi1 specification in the medulla and L4 specification in the lamina. Additionally, Bsh is at least required for L5 specification. In the absence of Bsh, L5 is transformed into glial cells.

  12. 77 FR 71477 - Reports, Forms, and Recordkeeping Requirements; Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ... barriers to participation. Additionally, the proposed survey would be voluntary and anonymous; the surveys... voluntary and anonymous. Estimated Total Annual Burden: NHTSA estimates interviews would require an...

  13. 76 FR 60599 - Reports, Forms and Recordkeeping Requirements Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-29

    ... and households Abstract Under 49 U.S.C. 30166(e), NHTSA reasonably may require a manufacturer of a...) requires manufacturers to notify NHTSA and owners, purchasers, and dealers if the manufacturer (1) learn... decide if and when a manufacturer learned of a safety-related defect or decided in good faith that...

  14. 76 FR 15364 - Reports, Forms and Record Keeping Requirements; Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-21

    ... No. 209, ``Seat belt assemblies,'' requires safety belts to be labeled with the year of manufacture... replacement belts are required to be accompanied by an installation instruction sheet (S4.1(k)). Seat belt... include brake fluid warning, glazing labeling, safety belt ] labeling, and vehicle certification...

  15. 76 FR 78662 - Agency Recordkeeping/Reporting Requirements Under Emergency Review by the Office of Management...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-19

    ... training and data grants are governed by the ``new grant'' PI and the basic grant is governed by the ``basic grant'' PI. Current PIs require separate applications and program assessment reports for each... by consolidating the PIs into one single PI and requiring one single, consolidated application...

  16. 40 CFR 68.215 - Permit content and air permitting authority or designated agency requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... this section, use one or more mechanisms such as, but not limited to, a completeness check, source... the requirements of this part; and (4) Initiate enforcement action based on paragraphs (e)(1) and...

  17. 40 CFR 68.215 - Permit content and air permitting authority or designated agency requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... this section, use one or more mechanisms such as, but not limited to, a completeness check, source... the requirements of this part; and (4) Initiate enforcement action based on paragraphs (e)(1) and...

  18. 78 FR 47015 - Software Requirement Specifications for Digital Computer Software Used in Safety Systems of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-02

    ... COMMISSION Software Requirement Specifications for Digital Computer Software Used in Safety Systems of... 1 of RG 1.172, ``Software Requirement Specifications for Digital Computer Software used in Safety... well as the software elements of those systems. This RG is one of six RG revisions addressing...

  19. 77 FR 50726 - Software Requirement Specifications for Digital Computer Software and Complex Electronics Used in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... COMMISSION Software Requirement Specifications for Digital Computer Software and Complex Electronics Used in... Digital Computer Software and Complex Electronics used in Safety Systems of Nuclear Power Plants.'' The DG... Requirement Specifications for Digital Computer Software and Complex Electronics used in Safety Systems...

  20. 40 CFR 270.16 - Specific part B information requirements for tank systems.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Permit Application § 270.16 Specific part B information requirements for tank systems. Except as... 40 Protection of Environment 28 2013-07-01 2013-07-01 false Specific part B information requirements for tank systems. 270.16 Section 270.16 Protection of Environment ENVIRONMENTAL PROTECTION...

  1. 40 CFR 270.16 - Specific part B information requirements for tank systems.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Permit Application § 270.16 Specific part B information requirements for tank systems. Except as... 40 Protection of Environment 27 2011-07-01 2011-07-01 false Specific part B information requirements for tank systems. 270.16 Section 270.16 Protection of Environment ENVIRONMENTAL PROTECTION...

  2. 40 CFR 270.16 - Specific part B information requirements for tank systems.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Permit Application § 270.16 Specific part B information requirements for tank systems. Except as... 40 Protection of Environment 27 2014-07-01 2014-07-01 false Specific part B information requirements for tank systems. 270.16 Section 270.16 Protection of Environment ENVIRONMENTAL PROTECTION...

  3. 40 CFR 270.16 - Specific part B information requirements for tank systems.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Permit Application § 270.16 Specific part B information requirements for tank systems. Except as... 40 Protection of Environment 28 2012-07-01 2012-07-01 false Specific part B information requirements for tank systems. 270.16 Section 270.16 Protection of Environment ENVIRONMENTAL PROTECTION...

  4. 10 CFR 810.12 - Information required in an application for specific authorization.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Information required in an application for specific authorization. 810.12 Section 810.12 Energy DEPARTMENT OF ENERGY ASSISTANCE TO FOREIGN ATOMIC ENERGY ACTIVITIES § 810.12 Information required in an application for specific authorization. Each application...

  5. 10 CFR 810.12 - Information required in an application for specific authorization.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Information required in an application for specific authorization. 810.12 Section 810.12 Energy DEPARTMENT OF ENERGY ASSISTANCE TO FOREIGN ATOMIC ENERGY ACTIVITIES § 810.12 Information required in an application for specific authorization. Each application...

  6. 41 CFR 302-9.170 - Under what specific conditions may my agency authorize transportation of a POV to my post of duty...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... conditions may my agency authorize transportation of a POV to my post of duty subsequent to the time of my assignment to that post? 302-9.170 Section 302-9.170 Public Contracts and Property Management Federal Travel... Subsequent to the Time of Assignment § 302-9.170 Under what specific conditions may my agency...

  7. 41 CFR 302-9.170 - Under what specific conditions may my agency authorize transportation of a POV to my post of duty...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... conditions may my agency authorize transportation of a POV to my post of duty subsequent to the time of my assignment to that post? 302-9.170 Section 302-9.170 Public Contracts and Property Management Federal Travel... Subsequent to the Time of Assignment § 302-9.170 Under what specific conditions may my agency...

  8. 41 CFR 302-9.170 - Under what specific conditions may my agency authorize transportation of a POV to my post of duty...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... conditions may my agency authorize transportation of a POV to my post of duty subsequent to the time of my assignment to that post? 302-9.170 Section 302-9.170 Public Contracts and Property Management Federal Travel... the Time of Assignment § 302-9.170 Under what specific conditions may my agency...

  9. 41 CFR 302-9.170 - Under what specific conditions may my agency authorize transportation of a POV to my post of duty...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... conditions may my agency authorize transportation of a POV to my post of duty subsequent to the time of my assignment to that post? 302-9.170 Section 302-9.170 Public Contracts and Property Management Federal Travel... Subsequent to the Time of Assignment § 302-9.170 Under what specific conditions may my agency...

  10. 41 CFR 302-9.170 - Under what specific conditions may my agency authorize transportation of a POV to my post of duty...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... conditions may my agency authorize transportation of a POV to my post of duty subsequent to the time of my assignment to that post? 302-9.170 Section 302-9.170 Public Contracts and Property Management Federal Travel... the Time of Assignment § 302-9.170 Under what specific conditions may my agency...

  11. Tools reference manual for a Requirements Specification Language (RSL), version 2.0

    NASA Technical Reports Server (NTRS)

    Fisher, Gene L.; Cohen, Gerald C.

    1993-01-01

    This report describes a general-purpose Requirements Specification Language, RSL. The purpose of RSL is to specify precisely the external structure of a mechanized system and to define requirements that the system must meet. A system can be comprised of a mixture of hardware, software, and human processing elements. RSL is a hybrid of features found in several popular requirements specification languages, such as SADT (Structured Analysis and Design Technique), PSL (Problem Statement Language), and RMF (Requirements Modeling Framework). While languages such as these have useful features for structuring a specification, they generally lack formality. To overcome the deficiencies of informal requirements languages, RSL has constructs for formal mathematical specification. These constructs are similar to those found in formal specification languages such as EHDM (Enhanced Hierarchical Development Methodology), Larch, and OBJ3.

  12. 78 FR 36633 - Reports, Forms and Record Keeping Requirements, Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-18

    ... TRANSPORTATION National Highway Traffic Safety Administration Reports, Forms and Record Keeping Requirements... Affairs, Office of Management and Budget, 725--17th Street NW., Washington, DC 20503, Attention NHTSA Desk... automated collection techniques or other forms of information technology. A comment to OMB is most...

  13. 76 FR 34081 - Agency Information Collection Activities; Proposed Collection; Comment Request; Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-10

    ... notice solicits comments on the requirement for an abbreviated new drug application (ANDA) applicant to... criteria, which are performed on a drug product formulation submitted for approval under an ANDA, or in an amendment to an ANDA that contains BE studies. In the final rule, FDA amended Sec. Sec. 314.94(a)(7)(i),...

  14. 76 FR 66352 - Reports, Forms and Record Keeping Requirements, Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-26

    ... manufacturers of new tractors and trailers are required to certify that their products are equipped with... tractors and trailers will be complicated. Labeling is also important to small trailer manufactures because... obvious from inspection, the marking system is necessary for tractor and trailer manufacturers and...

  15. 76 FR 24959 - Reports, Forms, and Record Keeping Requirements; Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-03

    ..., Washington, DC 20590. Mr. Stevens' telephone number is (202) 366-5308. Please identify the relevant... manufacturers of motor vehicles and items of replacement equipment to conduct a notification and remedy campaign... Federal Motor Vehicle Safety Standard (FMVSS). Those sections require a manufacturer of motor vehicles...

  16. 34 CFR 682.414 - Records, reports, and inspection requirements for guaranty agency programs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION (CONTINUED) FEDERAL FAMILY EDUCATION LOAN (FFEL) PROGRAM Administration of the Federal Family Education Loan Programs by a Guaranty... 34 Education 4 2014-07-01 2014-07-01 false Records, reports, and inspection requirements...

  17. 34 CFR 682.414 - Records, reports, and inspection requirements for guaranty agency programs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION (CONTINUED) FEDERAL FAMILY EDUCATION LOAN (FFEL) PROGRAM Administration of the Federal Family Education Loan Programs by a Guaranty... 34 Education 4 2012-07-01 2012-07-01 false Records, reports, and inspection requirements...

  18. 34 CFR 682.414 - Records, reports, and inspection requirements for guaranty agency programs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION (CONTINUED) FEDERAL FAMILY EDUCATION LOAN (FFEL) PROGRAM Administration of the Federal Family Education Loan Programs by a Guaranty... 34 Education 4 2011-07-01 2011-07-01 false Records, reports, and inspection requirements...

  19. 34 CFR 682.414 - Records, reports, and inspection requirements for guaranty agency programs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION (CONTINUED) FEDERAL FAMILY EDUCATION LOAN (FFEL) PROGRAM Administration of the Federal Family Education Loan Programs by a Guaranty... 34 Education 4 2013-07-01 2013-07-01 false Records, reports, and inspection requirements...

  20. 76 FR 4420 - Reports, Forms and Record Keeping Requirements Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-25

    .... Abstract: Part 575 requires tire manufacturers and tire brand name owners to submit reports to NHTSA... grading system; (3) the tire manufacturer or brand name owner provides prospective purchasers of tires the... tire manufacturers and brand name owners offering passenger car tires for sale in the United...

  1. 75 FR 9633 - Reports, Forms and Record Keeping Requirements; Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-03

    ... Highway Traffic Safety Administration Title: Part 585--Advanced Air Bag Phase-In Reporting Requirements... bags. Phase 1 of the advanced air bag phase-in began September 1, 2003 with 100 percent compliance by September 1, 2005. Phase 2 of the advanced air bag phase-in begins September 1, 2007 with 100...

  2. 36 CFR 1222.24 - How do agencies establish recordkeeping requirements?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... created or received on electronic mail systems. Recordkeeping requirements must: (1) Identify and... personnel in the course of their official duties; (2) Specify the use of materials and recording techniques... manner in which these materials must be maintained wherever held; (4) Propose how long records must...

  3. 75 FR 38863 - Reports, Forms, and Record Keeping Requirements Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-06

    ...: Motivations for Speeding. Type of Request: New information collection requirement. Abstract: Speeding is one... imperative that NHTSA gain a better understanding of the motivations for speeding behaviors in order to... countermeasures. The focus groups are expected to provide data relevant to descriptions of key...

  4. 76 FR 78668 - Agency Information Collection Activities; Proposed Collection; Comment Request; Requirements on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-19

    ... Biological Products'' (the Final Rule), which published on January 24, 2006 (71 FR 3922), and was effective... Burden The PRA information collection analysis in the final rule (71 FR 3964-3967) (currently approved... Collection; Comment Request; Requirements on Content and Format of Labeling for Human Prescription Drug...

  5. 49 CFR 180.509 - Requirements for inspection and test of specification tank cars.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 3 2012-10-01 2012-10-01 false Requirements for inspection and test of... Requirements for inspection and test of specification tank cars. (a) General. Each tank car owner must ensure that a tank car facility: (1) Inspects and tests each item according to the requirements specified...

  6. 49 CFR 180.509 - Requirements for inspection and test of specification tank cars.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 3 2014-10-01 2014-10-01 false Requirements for inspection and test of... Requirements for inspection and test of specification tank cars. (a) General. Each tank car owner must ensure that a tank car facility: (1) Inspects and tests each item according to the requirements specified...

  7. 49 CFR 180.509 - Requirements for inspection and test of specification tank cars.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 3 2013-10-01 2013-10-01 false Requirements for inspection and test of... Requirements for inspection and test of specification tank cars. (a) General. Each tank car owner must ensure that a tank car facility: (1) Inspects and tests each item according to the requirements specified...

  8. 40 CFR 63.1095 - What specific requirements must I comply with?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... according to any of the options in 40 CFR 61.342(c)(1) through (e) or transfer waste off-site. If you elect... Systems and Waste Operations Waste Requirements § 63.1095 What specific requirements must I comply with? For waste that is not transferred off-site, you must comply with the requirements in paragraph (a)...

  9. 76 FR 30238 - Reports, Forms, and Recordkeeping Requirements Agency Information Collection Activity Under OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ... information from state level reporting entities that can be used to measure the progress of 9-1-1 authorities... proposed effort, NHTSA would specifically request reporting entities to voluntarily collect and annually... reporting entity, for a total of 168 hours for all entities. The respondents would not incur any...

  10. 49 CFR 179.301 - Individual specification requirements for multi-unit tank car tanks.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...-unit tank car tanks. 179.301 Section 179.301 Transportation Other Regulations Relating to... (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Multi-Unit Tank Car Tanks (Classes DOT-106A and 110AW) § 179.301 Individual specification requirements for multi-unit tank car tanks. (a) In addition...

  11. 49 CFR 179.201 - Individual specification requirements applicable to non-pressure tank car tanks.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... to non-pressure tank car tanks. 179.201 Section 179.201 Transportation Other Regulations Relating to... (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.201 Individual specification requirements applicable to non-pressure tank car tanks....

  12. 49 CFR 179.101 - Individual specification requirements applicable to pressure tank car tanks.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... to pressure tank car tanks. 179.101 Section 179.101 Transportation Other Regulations Relating to... (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120) § 179.101 Individual specification requirements applicable to pressure tank...

  13. 49 CFR 179.201 - Individual specification requirements applicable to non-pressure tank car tanks.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... to non-pressure tank car tanks. 179.201 Section 179.201 Transportation Other Regulations Relating to... (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.201 Individual specification requirements applicable to non-pressure tank car tanks....

  14. 49 CFR 179.301 - Individual specification requirements for multi-unit tank car tanks.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...-unit tank car tanks. 179.301 Section 179.301 Transportation Other Regulations Relating to... (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Multi-Unit Tank Car Tanks (Classes DOT-106A and 110AW) § 179.301 Individual specification requirements for multi-unit tank car tanks. (a) In addition...

  15. 49 CFR 179.101 - Individual specification requirements applicable to pressure tank car tanks.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... to pressure tank car tanks. 179.101 Section 179.101 Transportation Other Regulations Relating to... (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120) § 179.101 Individual specification requirements applicable to pressure tank...

  16. 49 CFR 179.101 - Individual specification requirements applicable to pressure tank car tanks.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... to pressure tank car tanks. 179.101 Section 179.101 Transportation Other Regulations Relating to... (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120) § 179.101 Individual specification requirements applicable to pressure tank...

  17. 49 CFR 179.301 - Individual specification requirements for multi-unit tank car tanks.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...-unit tank car tanks. 179.301 Section 179.301 Transportation Other Regulations Relating to... (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Multi-Unit Tank Car Tanks (Classes DOT-106A and 110AW) § 179.301 Individual specification requirements for multi-unit tank car tanks. (a) In addition...

  18. 49 CFR 179.101 - Individual specification requirements applicable to pressure tank car tanks.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... to pressure tank car tanks. 179.101 Section 179.101 Transportation Other Regulations Relating to... (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120) § 179.101 Individual specification requirements applicable to pressure tank...

  19. 49 CFR 179.201 - Individual specification requirements applicable to non-pressure tank car tanks.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... to non-pressure tank car tanks. 179.201 Section 179.201 Transportation Other Regulations Relating to... (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Non-Pressure Tank Car Tanks (Classes DOT-111AW and 115AW) § 179.201 Individual specification requirements applicable to non-pressure tank car tanks....

  20. 49 CFR 179.301 - Individual specification requirements for multi-unit tank car tanks.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-unit tank car tanks. 179.301 Section 179.301 Transportation Other Regulations Relating to... MATERIALS REGULATIONS SPECIFICATIONS FOR TANK CARS Specifications for Multi-Unit Tank Car Tanks (Classes DOT-106A and 110AW) § 179.301 Individual specification requirements for multi-unit tank car tanks. (a)...

  1. Future Defense Communications Agency Network Requirements in Support of Department of Defense Office Automation.

    DTIC Science & Technology

    1981-02-01

    Society [1] and The Network Nation [2]. Specifically, the report attempts to foresee trends in present and developing technologies which may impact on...projections of technology are probably valid for only about five years, based upon what exists now at the forefront (11. Martin, J, The Wired Society , Prcntice...FUNDS TRANSFER Electronic Funds Transfor (EFT) refers to the concept of a checkless, cashless transaction mechanism by which funds are transferred

  2. 41 CFR 102-33.385 - Is any civilian executive agency exempt from the requirement to report information to GSA on...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... executive agency exempt from the requirement to report information to GSA on Government aircraft? 102-33.385... (Continued) FEDERAL MANAGEMENT REGULATION PERSONAL PROPERTY 33-MANAGEMENT OF GOVERNMENT AIRCRAFT Reporting Information on Government Aircraft Overview § 102-33.385 Is any civilian executive agency exempt from...

  3. 41 CFR 102-33.385 - Is any civilian executive agency exempt from the requirement to report information to GSA on...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... executive agency exempt from the requirement to report information to GSA on Government aircraft? 102-33.385... (Continued) FEDERAL MANAGEMENT REGULATION PERSONAL PROPERTY 33-MANAGEMENT OF GOVERNMENT AIRCRAFT Reporting Information on Government Aircraft Overview § 102-33.385 Is any civilian executive agency exempt from...

  4. 41 CFR 102-33.385 - Is any civilian executive agency exempt from the requirement to report information to GSA on...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... executive agency exempt from the requirement to report information to GSA on Government aircraft? 102-33.385... (Continued) FEDERAL MANAGEMENT REGULATION PERSONAL PROPERTY 33-MANAGEMENT OF GOVERNMENT AIRCRAFT Reporting Information on Government Aircraft Overview § 102-33.385 Is any civilian executive agency exempt from...

  5. 41 CFR 102-33.385 - Is any civilian executive agency exempt from the requirement to report information to GSA on...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... executive agency exempt from the requirement to report information to GSA on Government aircraft? 102-33.385... (Continued) FEDERAL MANAGEMENT REGULATION PERSONAL PROPERTY 33-MANAGEMENT OF GOVERNMENT AIRCRAFT Reporting Information on Government Aircraft Overview § 102-33.385 Is any civilian executive agency exempt from...

  6. 41 CFR 102-33.385 - Is any civilian executive agency exempt from the requirement to report information to GSA on...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... executive agency exempt from the requirement to report information to GSA on Government aircraft? 102-33.385... (Continued) FEDERAL MANAGEMENT REGULATION PERSONAL PROPERTY 33-MANAGEMENT OF GOVERNMENT AIRCRAFT Reporting Information on Government Aircraft Overview § 102-33.385 Is any civilian executive agency exempt from...

  7. Inter-Service/Agency Automated Message Processing Exchange Program. Functional Requirements Description and Interface Control Document.

    DTIC Science & Technology

    1983-11-01

    sustained basis is 50 KBPS (77 line blocks per second; which is expected to equate to 3 output messages per second, 3.5.1.1.1 Input Traffic...letter or letters that equate to the specific addressees »tor example NSA/DELTA or MSA/ALFA CHARLIE). A P D may contain more than...Special] SEC TCC Note that an error in R-Community TRC field is coded as -TRC whether or not a true TRC may have been intenced . The same is true of

  8. Standards Applicable to Generators of Hazardous Waste; Alternative Requirements for Hazardous Waste Determination and Accumulation of Unwanted Material at Laboratories Owned by Colleges and Universities and Other Eligible Academic Entities Formally Affiliated With Colleges and Universities. Final Rule. Federal Register, Environmental Protection Agency. 40 CFR Parts 261 and 262. Part II

    ERIC Educational Resources Information Center

    National Archives and Records Administration, 2008

    2008-01-01

    The Environmental Protection Agency (EPA or the Agency) is finalizing an alternative set of generator requirements applicable to laboratories owned by eligible academic entities, as defined in this final rule. The rule provides a flexible and protective set of regulations that address the specific nature of hazardous waste generation and…

  9. The Mitochondrial Lon Protease Is Required for Age-Specific and Sex-Specific Adaptation to Oxidative Stress.

    PubMed

    Pomatto, Laura C D; Carney, Caroline; Shen, Brenda; Wong, Sarah; Halaszynski, Kelly; Salomon, Matthew P; Davies, Kelvin J A; Tower, John

    2017-01-09

    Multiple human diseases involving chronic oxidative stress show a significant sex bias, including neurodegenerative diseases, cancer, immune dysfunction, diabetes, and cardiovascular disease. However, a possible molecular mechanism for the sex bias in physiological adaptation to oxidative stress remains unclear. Here, we report that Drosophila melanogaster females but not males adapt to hydrogen peroxide stress, whereas males but not females adapt to paraquat (superoxide) stress. Stress adaptation in each sex requires the conserved mitochondrial Lon protease and is associated with sex-specific expression of Lon protein isoforms and proteolytic activity. Adaptation to oxidative stress is lost with age in both sexes. Transgenic expression of transformer gene during development transforms chromosomal males into pseudo-females and confers the female-specific pattern of Lon isoform expression, Lon proteolytic activity induction, and H2O2 stress adaptation; these effects were also observed using adult-specific transformation. Conversely, knockdown of transformer in chromosomal females eliminates the female-specific Lon isoform expression, Lon proteolytic activity induction, and H2O2 stress adaptation and produces the male-specific paraquat (superoxide) stress adaptation. Sex-specific expression of alternative Lon isoforms was also observed in mouse tissues. The results develop Drosophila melanogaster as a model for sex-specific stress adaptation regulated by the Lon protease, with potential implications for understanding sexual dimorphism in human disease.

  10. 49 CFR 180.205 - General requirements for requalification of specification cylinders.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... for steel and nickel cylinders (IBR, see § 171.7 of this subchapter); C-6.1 for seamless aluminum... requirements prescribed in this paragraph (f), each specification cylinder manufactured of aluminum alloy...

  11. 49 CFR 180.205 - General requirements for requalification of specification cylinders.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... for steel and nickel cylinders (IBR, see § 171.7 of this subchapter); C-6.1 for seamless aluminum... requirements prescribed in this paragraph (f), each specification cylinder manufactured of aluminum alloy...

  12. 49 CFR 180.205 - General requirements for requalification of specification cylinders.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... for steel and nickel cylinders (IBR, see § 171.7 of this subchapter); C-6.1 for seamless aluminum... requirements prescribed in this paragraph (f), each specification cylinder manufactured of aluminum alloy...

  13. 49 CFR 180.205 - General requirements for requalification of specification cylinders.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... for steel and nickel cylinders (IBR, see § 171.7 of this subchapter); C-6.1 for seamless aluminum... requirements prescribed in this paragraph (f), each specification cylinder manufactured of aluminum alloy...

  14. AMTD: Update of Engineering Specifications Derived from Science Requirements for Future UVOIR Space Telescopes

    NASA Technical Reports Server (NTRS)

    Stahl, H. Philip

    2014-01-01

    AMTD is using a Science Driven Systems Engineering approach to develop Engineering Specifications based on Science Measurement Requirements and Implementation Constraints. Science requirements meet the needs of both Exoplanet and General Astrophysics science. Engineering Specifications are guiding our effort to mature to TRL-6 the critical technologies needed to produce 4-m or larger flight-qualified UVOIR mirrors by 2018 so that a viable mission can be considered by the 2020 Decadal Review.

  15. 49 CFR 180.509 - Requirements for inspection and test of specification tank cars.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... metal jacket or with a thermal protection system shall have an inspection and test conforming to this... 49 Transportation 3 2011-10-01 2011-10-01 false Requirements for inspection and test of... Requirements for inspection and test of specification tank cars. (a) General. (1) Each tank car facility...

  16. 46 CFR 189.55-5 - Plans and specifications required for new construction.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) OCEANOGRAPHIC RESEARCH VESSELS INSPECTION AND CERTIFICATION Plan Approval § 189.55-5 Plans and specifications... bottom plating and framing. 1 The asterisk (*) indicates items which may require approval by the American..., carbon dioxide, foam and sprinkling systems. (e) Marine engineering. For plans required for...

  17. 46 CFR 189.55-5 - Plans and specifications required for new construction.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) OCEANOGRAPHIC RESEARCH VESSELS INSPECTION AND CERTIFICATION Plan Approval § 189.55-5 Plans and specifications... bottom plating and framing. 1 The asterisk (*) indicates items which may require approval by the American..., carbon dioxide, clean agent, foam, and sprinkling systems. (e) Marine engineering. For plans required...

  18. 10 CFR 72.236 - Specific requirements for spent fuel storage cask approval and fabrication.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Specific requirements for spent fuel storage cask approval and fabrication. 72.236 Section 72.236 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND...

  19. 10 CFR 40.32 - General requirements for issuance of specific licenses.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... weighing the environmental, economic, technical and other benefits against environmental costs and... satisfies any applicable special requirements contained in § 40.34. (g) If the proposed activity involves... 10 Energy 1 2010-01-01 2010-01-01 false General requirements for issuance of specific licenses....

  20. 10 CFR 30.33 - General requirements for issuance of specific licenses.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... part 51 of this chapter, has concluded, after weighing the environmental, economic, technical, and... protection of environmental values. (b) Upon a determination that an application meets the requirements of... 10 Energy 1 2010-01-01 2010-01-01 false General requirements for issuance of specific licenses....

  1. 49 CFR 180.209 - Requirements for requalification of specification cylinders.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Requirements for requalification of specification cylinders. (a) Periodic qualification of cylinders. Each specification cylinder that becomes due for periodic requalification, as specified in the following table, must... records must be maintained in accordance with § 180.215. Table 1 follows: Table 1—Requalification...

  2. 7 CFR 1724.54 - Requirements for RUS approval of plans and specifications.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... DESIGN POLICIES AND PROCEDURES Electric System Design § 1724.54 Requirements for RUS approval of plans... specifications for transmission construction projects which are not based on RUS approved line design data or do... section, plans and specifications for transmission construction which use previously approved design...

  3. An introduction to requirements capture using PVS: Specification of a simple autopilot

    NASA Technical Reports Server (NTRS)

    Butler, Ricky W.

    1996-01-01

    This paper presents an introduction to capturing software requirements in the PVS formal language. The object of study is a simplified digital autopilot that was motivated in part by the mode control panel of NASA Langley's Boeing 737 research aircraft. The paper first presents the requirements for this autopilot in English and then steps the reader through a translation of these requirements into formal mathematics. Along the way deficiencies in the English specification are noted and repaired. Once completed, the formal PVS requirement is analyzed using the PVS theorem prover and shown to maintain an invariant over its state space.

  4. Federal Agency Satellite Requirements.

    DTIC Science & Technology

    1985-07-01

    detect sizable areas of standing water, and to recognize drought conditions and their onset. In the Sahel , for example, observations from about 50...Regional Environmental Problems d AID believes that far more can be done to estimate agricultural production in threatened regional areas such as the Sahel ...management activities. Remotely sensed data show only the land surface, and the information on the occurrence and salinity of ground water must be

  5. 41 CFR 102-75.1045 - Are there exceptions to the policy that requires public notice be given before Federal agencies...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Are there exceptions to the policy that requires public notice be given before Federal agencies abandon or destroy... Abandonment and Destruction § 102-75.1045 Are there exceptions to the policy that requires public notice...

  6. 34 CFR 222.81 - What requirements must a local educational agency meet to be eligible for a payment under section...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... to be eligible for a payment under section 8003(g) of the Act? 222.81 Section 222.81 Education... Disabilities Under Section 8003(g) of the Act § 222.81 What requirements must a local educational agency meet... Act for children identified in paragraph (b) of this section and meets the requirements of §§...

  7. A Methodology for Writing High Quality Requirements Specification and Evaluating Existing Ones

    NASA Technical Reports Server (NTRS)

    Rosenberg, Linda; Hammer, Theodore

    1999-01-01

    Requirements development and management have always been critical in the implementation of software systems; engineers are unable to build what analysts can't define. It is generally accepted that the earlier in the life cycle potential risks are identified the easier it is to eliminate or manage the conditions that introduce that risk. Problems that are not found until testing are approximately 14 times more costly to fix than if the problem was found in the requirement phase. The requirements specification, as the first tangible representation of the capability to be produced, establishes the basis for all of the project's engineering management and assurance functions. If the quality of the requirements specification is poor it can give rise to risks in all areas of the project. Recently, automated tools have become available to support requirements management. The use of these tools not only provides support in the definition and tracing of requirements, but it also opens the door to effective use of metrics in characterizing and assessing the quality of the requirement specifications.

  8. A Methodology for Writing High Quality Requirement Specifications and for Evaluating Existing Ones

    NASA Technical Reports Server (NTRS)

    Rosenberg, Linda; Hammer, Theodore

    1999-01-01

    Requirements development and management have always been critical in the implementation of software systems-engineers are unable to build what analysts can not define. It is generally accepted that the earlier in the life cycle potential risks are identified the easier it is to eliminate or manage the conditions that introduce that risk. Problems that are not found until testing are approximately 14 times more costly to fix than if the problem was found in the requirement phase. The requirements specification, as the first tangible representation of the capability to be produced, establishes the basis for all of the project's engineering management and assurance functions. If the quality of the requirements specification is poor it can give rise to risks in all areas of the project. Recently, automated tools have become available to support requirements management. The use of these tools not only provides support in the definition and tracing of requirements, but it also opens the door to effective use of metrics in characterizing and assessing the quality of the requirement specifications.

  9. Towards the formal specification of the requirements and design of a processor interface unit: HOL listings

    NASA Technical Reports Server (NTRS)

    Fura, David A.; Windley, Phillip J.; Cohen, Gerald C.

    1993-01-01

    This technical report contains the HOL listings of the specification of the design and major portions of the requirements for a commercially developed processor interface unit (or PIU). The PIU is an interface chip performing memory interface, bus interface, and additional support services for a commercial microprocessor within a fault-tolerant computer system. This system, the Fault-Tolerant Embedded Processor (FTEP), is targeted towards applications in avionics and space requiring extremely high levels of mission reliability, extended maintenance-free operation, or both. This report contains the actual HOL listings of the PIU specification as it currently exists. Section two of this report contains general-purpose HOL theories that support the PIU specification. These theories include definitions for the hardware components used in the PIU, our implementation of bit words, and our implementation of temporal logic. Section three contains the HOL listings for the PIU design specification. Aside from the PIU internal bus (I-Bus), this specification is complete. Section four contains the HOL listings for a major portion of the PIU requirements specification. Specifically, it contains most of the definition for the PIU behavior associated with memory accesses initiated by the local processor.

  10. New synchronous compensators for the Nelson River HVDC system; Planning requirements and specifications

    SciTech Connect

    Thio, C.V.; Davies, J.B. )

    1991-04-01

    The first units of Limestone Generating Station, the third plant on the Lower Nelson River in northern Manitoba, will come into service in the fall of 1990. Additional var compensation equipment is required at the inverter end of the Nelson River HVdc system to accommodate power from Limestone. This paper describes the system requirements of and the overall specification for the synchronous compensators selected to supply the reactive power and voltage support.

  11. 36 CFR 1222.22 - What records are required to provide for adequate documentation of agency business?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF..., agencies must prescribe the creation and maintenance of records that: (a) Document the persons,...

  12. 36 CFR 1222.22 - What records are required to provide for adequate documentation of agency business?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF..., agencies must prescribe the creation and maintenance of records that: (a) Document the persons,...

  13. 36 CFR 1222.22 - What records are required to provide for adequate documentation of agency business?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF..., agencies must prescribe the creation and maintenance of records that: (a) Document the persons,...

  14. 36 CFR 1222.22 - What records are required to provide for adequate documentation of agency business?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF..., agencies must prescribe the creation and maintenance of records that: (a) Document the persons,...

  15. 36 CFR 1222.22 - What records are required to provide for adequate documentation of agency business?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF..., agencies must prescribe the creation and maintenance of records that: (a) Document the persons,...

  16. Formal specification of requirements for analytical redundancy-based fault-tolerant flight control systems

    NASA Astrophysics Data System (ADS)

    Del Gobbo, Diego

    2000-10-01

    Flight control systems are undergoing a rapid process of automation. The use of Fly-By-Wire digital flight control systems in commercial aviation (Airbus 320 and Boeing FBW-B777) is a clear sign of this trend. The increased automation goes in parallel with an increased complexity of flight control systems with obvious consequences on reliability and safety. Flight control systems must meet strict fault-tolerance requirements. The standard solution to achieving fault tolerance capability relies on multi-string architectures. On the other hand, multi-string architectures further increase the complexity of the system inducing a reduction of overall reliability. In the past two decades a variety of techniques based on analytical redundancy have been suggested for fault diagnosis purposes. While research on analytical redundancy has obtained desirable results, a design methodology involving requirements specification and feasibility analysis of analytical redundancy based fault tolerant flight control systems is missing. The main objective of this research work is to describe within a formal framework the implications of adopting analytical redundancy as a basis to achieve fault tolerance. The research activity involves analysis of the analytical redundancy approach, analysis of flight control system informal requirements, and re-engineering (modeling and specification) of the fault tolerance requirements. The USAF military specification MIL-F-9490D and supporting documents are adopted as source for the flight control informal requirements. The De Havilland DHC-2 general aviation aircraft equipped with standard autopilot control functions is adopted as pilot application. Relational algebra is adopted as formal framework for the specification of the requirements. The detailed analysis and formalization of the requirements resulted in a better definition of the fault tolerance problem in the framework of analytical redundancy. Fault tolerance requirements and related

  17. International Low Impact Docking System (iLIDS) Project Technical Requirements Specification, Revision F

    NASA Technical Reports Server (NTRS)

    Lewis, James L.

    2011-01-01

    The NASA Docking System (NDS) is NASA's implementation for the emerging International Docking System Standard (IDSS) using low impact docking technology. The NASA Docking System Project (NDSP) is the International Space Station (ISS) Program's project to produce the NDS, Common Docking Adapter (CDA) and Docking Hub. The NDS design evolved from the Low Impact Docking System (LIDS). The acronym international Low Impact Docking System (iLIDS) is also used to describe this system as well as the Government Furnished Equipment (GFE) project designing the NDS for the NDSP. NDS and iLIDS may be used interchangeability. This document will use the acronym iLIDS. Some of the heritage documentation and implementations (e.g., software command names, requirement identification (ID), figures, etc.) used on NDS will continue to use the LIDS acronym. This specification defines the technical requirements for the iLIDS GFE delivered to the NDSP by the iLIDS project. This document contains requirements for two iLIDS configurations, SEZ29101800-301 and SEZ29101800-302. Requirements with the statement, iLIDS shall, are for all configurations. Examples of requirements that are unique to a single configuration may be identified as iLIDS (-301) shall or iLIDS (-302) shall. Furthermore, to allow a requirement to encompass all configurations with an exception, the requirement may be designated as iLIDS (excluding -302) shall. Verification requirements for the iLIDS project are identified in the Verification Matrix (VM) provided in the iLIDS Verification and Validation Document, JSC-63966. The following definitions differentiate between requirements and other statements: Shall: This is the only verb used for the binding requirements. Should/May: These verbs are used for stating non-mandatory goals. Will: This verb is used for stating facts or declaration of purpose. A Definition of Terms table is provided in Appendix B to define those terms with specific tailored uses in this document.

  18. 41 CFR 301-52.3 - Am I required to file a travel claim in a specific format and must the claim be signed?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... soon as your agency fully deploys the E-Gov Travel Service (ETS), you must use the ETS to file all your travel claims. (Agencies are required to fully deploy the ETS no later than September 30, 2006.)...

  19. 24 CFR 200.952 - Supplementary specific requirements under the HUD building product standards and certification...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Supplementary specific requirements... treads. 200.952 Section 200.952 Housing and Urban Development Regulations Relating to Housing and Urban... HOUSING AND URBAN DEVELOPMENT GENERAL INTRODUCTION TO FHA PROGRAMS Minimum Property Standards §...

  20. 24 CFR 200.955 - Supplementary specific requirements under the HUD building product standard and certification...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Supplementary specific requirements... doors). 200.955 Section 200.955 Housing and Urban Development Regulations Relating to Housing and Urban... HOUSING AND URBAN DEVELOPMENT GENERAL INTRODUCTION TO FHA PROGRAMS Minimum Property Standards §...

  1. 10 CFR 40.32 - General requirements for issuance of specific licenses.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false General requirements for issuance of specific licenses. 40.32 Section 40.32 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC LICENSING OF SOURCE MATERIAL License... applicant is qualified by reason of training and experience to use the source material for the...

  2. 40 CFR 86.1306-07 - Equipment required and specifications; overview.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... simultaneous tests. This comparison shall be performed over the “hot-start” portion of the FTP test cycle. If... (CONTINUED) Emission Regulations for New Otto-Cycle and Diesel Heavy-Duty Engines; Gaseous and Particulate Exhaust Test Procedures § 86.1306-07 Equipment required and specifications; overview. Section...

  3. 40 CFR 86.1306-07 - Equipment required and specifications; overview.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... simultaneous tests. This comparison shall be performed over the “hot-start” portion of the FTP test cycle. If... (CONTINUED) Emission Regulations for New Otto-Cycle and Diesel Heavy-Duty Engines; Gaseous and Particulate Exhaust Test Procedures § 86.1306-07 Equipment required and specifications; overview. Section...

  4. 40 CFR 86.1306-07 - Equipment required and specifications; overview.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... simultaneous tests. This comparison shall be performed over the “hot-start” portion of the FTP test cycle. If... (CONTINUED) Emission Regulations for New Otto-Cycle and Diesel Heavy-Duty Engines; Gaseous and Particulate Exhaust Test Procedures § 86.1306-07 Equipment required and specifications; overview. Section...

  5. 49 CFR 180.205 - General requirements for requalification of specification cylinders.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) Periodic requalification of cylinders. Each cylinder bearing a DOT specification marking must be requalified and marked as specified in the Requalification Table in this subpart. Each cylinder bearing a DOT... inspection of cylinders. Without regard to any other periodic requalification requirements, a cylinder...

  6. A Methodology for Systems Requirements Specification and Traceability for Large Real Time Complex Systems

    DTIC Science & Technology

    1991-09-27

    The ECS block is divided into four projects : Systems Design Synthesis Technology, Systems Evaluation and Assessment Technology, Systems Reengineering...Technology, and Engineering Application Prototype. These projects work closely together to incorporate new technology across the entire system...development life cycle. The Requirements Specification and Traceability Task is within the Systems Design Synthesis Technology Project . The project looks at

  7. 24 CFR 200.943 - Supplementary specific requirements under the HUD building product standards and certification...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... under the HUD building product standards and certification program for the grademarking of lumber. 200... Supplementary specific requirements under the HUD building product standards and certification program for the... that the lumber was green or dry at the time of dressing; (7) Indication that the lumber was...

  8. 24 CFR 200.943 - Supplementary specific requirements under the HUD building product standards and certification...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... under the HUD building product standards and certification program for the grademarking of lumber. 200... Supplementary specific requirements under the HUD building product standards and certification program for the... that the lumber was green or dry at the time of dressing; (7) Indication that the lumber was...

  9. 24 CFR 200.943 - Supplementary specific requirements under the HUD building product standards and certification...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... under the HUD building product standards and certification program for the grademarking of lumber. 200... Supplementary specific requirements under the HUD building product standards and certification program for the... that the lumber was green or dry at the time of dressing; (7) Indication that the lumber was...

  10. 24 CFR 200.943 - Supplementary specific requirements under the HUD building product standards and certification...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... under the HUD building product standards and certification program for the grademarking of lumber. 200... Supplementary specific requirements under the HUD building product standards and certification program for the... that the lumber was green or dry at the time of dressing; (7) Indication that the lumber was...

  11. 24 CFR 200.943 - Supplementary specific requirements under the HUD building product standards and certification...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... under the HUD building product standards and certification program for the grademarking of lumber. 200... Supplementary specific requirements under the HUD building product standards and certification program for the... that the lumber was green or dry at the time of dressing; (7) Indication that the lumber was...

  12. 10 CFR 72.75 - Reporting requirements for specific events and conditions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Reporting requirements for specific events and conditions... events and conditions. (a) Emergency notifications: Each licensee shall notify the NRC Headquarters... possible but not later than four hours after the discovery of any of the following events or...

  13. 10 CFR 72.75 - Reporting requirements for specific events and conditions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Reporting requirements for specific events and conditions... events and conditions. (a) Emergency notifications: Each licensee shall notify the NRC Headquarters... possible but not later than four hours after the discovery of any of the following events or...

  14. 10 CFR 72.75 - Reporting requirements for specific events and conditions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Reporting requirements for specific events and conditions... events and conditions. (a) Emergency notifications: Each licensee shall notify the NRC Headquarters... possible but not later than four hours after the discovery of any of the following events or...

  15. 10 CFR 72.75 - Reporting requirements for specific events and conditions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false Reporting requirements for specific events and conditions... events and conditions. (a) Emergency notifications: Each licensee shall notify the NRC Headquarters... possible but not later than four hours after the discovery of any of the following events or...

  16. 10 CFR 72.75 - Reporting requirements for specific events and conditions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Reporting requirements for specific events and conditions... events and conditions. (a) Emergency notifications: Each licensee shall notify the NRC Headquarters... possible but not later than four hours after the discovery of any of the following events or...

  17. 49 CFR 173.457 - Transportation of fissile material packages-specific requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Transportation of fissile material packages-specific requirements. 173.457 Section 173.457 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS SHIPPERS-GENERAL...

  18. 7 CFR 1724.54 - Requirements for RUS approval of plans and specifications.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... and standard structures do not require RUS approval. Plans and specifications for related work, such... not use RUS standard structures must receive RUS approval prior to requesting bids on contracts or... application must show floor area and estimated cost breakdown between office building space and space...

  19. 7 CFR 1724.54 - Requirements for RUS approval of plans and specifications.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... and standard structures do not require RUS approval. Plans and specifications for related work, such... not use RUS standard structures must receive RUS approval prior to requesting bids on contracts or... application must show floor area and estimated cost breakdown between office building space and space...

  20. 7 CFR 1724.54 - Requirements for RUS approval of plans and specifications.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... and standard structures do not require RUS approval. Plans and specifications for related work, such... not use RUS standard structures must receive RUS approval prior to requesting bids on contracts or... application must show floor area and estimated cost breakdown between office building space and space...

  1. 7 CFR 1724.54 - Requirements for RUS approval of plans and specifications.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... and standard structures do not require RUS approval. Plans and specifications for related work, such... not use RUS standard structures must receive RUS approval prior to requesting bids on contracts or... application must show floor area and estimated cost breakdown between office building space and space...

  2. 33 CFR 149.615 - What construction drawings and specifications are required?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... HOMELAND SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: DESIGN, CONSTRUCTION, AND EQUIPMENT Design and Equipment General § 149.615 What construction drawings and specifications are required? (a) To... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false What construction drawings...

  3. 46 CFR 62.35-50 - Tabulated monitoring and safety control requirements for specific systems.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) Gas turbine (8) (8) (8) (8) (5) Engines and turbines Jacking/turning gear Engaged (8) Fuel oil (9) (9... instrumentation, alarms, and safety controls required for specific types of systems are listed in Table 62.35-50...) System Service Instrumentation Alarm Safety control Notes Main (Propulsion) boiler (1) (1) (1) (2)...

  4. 24 CFR 3280.904 - Specific requirements for designing the transportation system.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the transportation system. 3280.904 Section 3280.904 Housing and Urban Development Regulations... SAFETY STANDARDS Transportation § 3280.904 Specific requirements for designing the transportation system. (a) General. The entire system (frame, drawbar and coupling mechanism, running gear assembly,...

  5. 20 CFR 670.320 - What are the requirements for award of contracts and payments to Federal agencies?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... TRAINING ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) THE JOB CORPS UNDER TITLE I OF THE WORKFORCE... Acquisition Regulation (48 CFR Chapter 1); and the DOL Acquisition Regulation (48 CFR Chapter 29) apply to the award of contracts and to payments to Federal agencies. (b) Job Corps funding of Federal agencies...

  6. 20 CFR 670.320 - What are the requirements for award of contracts and payments to Federal agencies?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... TRAINING ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) THE JOB CORPS UNDER TITLE I OF THE WORKFORCE... Acquisition Regulation (48 CFR Chapter 1); and the DOL Acquisition Regulation (48 CFR Chapter 29) apply to the award of contracts and to payments to Federal agencies. (b) Job Corps funding of Federal agencies...

  7. 20 CFR 670.320 - What are the requirements for award of contracts and payments to Federal agencies?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... TRAINING ADMINISTRATION, DEPARTMENT OF LABOR THE JOB CORPS UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT... Regulation (48 CFR Chapter 1); and the DOL Acquisition Regulation (48 CFR Chapter 29) apply to the award of contracts and to payments to Federal agencies. (b) Job Corps funding of Federal agencies that operate...

  8. 49 CFR Appendix A to Part 228 - Requirements of the Hours of Service Act: Statement of Agency Policy and Interpretation

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...: Statement of Agency Policy and Interpretation A Appendix A to Part 228 Transportation Other Regulations... Service Act: Statement of Agency Policy and Interpretation First enacted in 1907, the Hours of Service Act... or operation of trains. Employees who perform this type of service commonly include...

  9. Towards the formal specification of the requirements and design of a processor interface unit

    NASA Technical Reports Server (NTRS)

    Fura, David A.; Windley, Phillip J.; Cohen, Gerald C.

    1993-01-01

    Work to formally specify the requirements and design of a Processor Interface Unit (PIU), a single-chip subsystem providing memory interface, bus interface, and additional support services for a commercial microprocessor within a fault-tolerant computer system, is described. This system, the Fault-Tolerant Embedded Processor (FTEP), is targeted towards applications in avionics and space requiring extremely high levels of mission reliability, extended maintenance free operation, or both. The approaches that were developed for modeling the PIU requirements and for composition of the PIU subcomponents at high levels of abstraction are described. These approaches were used to specify and verify a nontrivial subset of the PIU behavior. The PIU specification in Higher Order Logic (HOL) is documented in a companion NASA contractor report entitled 'Towards the Formal Specification of the Requirements and Design of a Processor Interfacs Unit - HOL Listings.' The subsequent verification approach and HOL listings are documented in NASA contractor report entitled 'Towards the Formal Verification of the Requirements and Design of a Processor Interface Unit' and NASA contractor report entitled 'Towards the Formal Verification of the Requirements and Design of a Processor Interface Unit - HOL Listings.'

  10. A discussion of higher order software concepts as they apply to functional requirements and specifications. [space shuttles and guidance

    NASA Technical Reports Server (NTRS)

    Hamilton, M.

    1973-01-01

    The entry guidance software functional requirements (requirements design phase), its architectural requirements (specifications design phase), and the entry guidance software verified code are discussed. It was found that the proper integration of designs at both the requirements and specifications levels are of high priority consideration.

  11. NASA specification for manufacturing and performance requirements of NASA standard aerospace nickel-cadmium cells

    NASA Technical Reports Server (NTRS)

    1988-01-01

    On November 25, 1985, the NASA Chief Engineer established a NASA-wide policy to maintain and to require the use of the NASA standard for aerospace nickel-cadmium cells and batteries. The Associate Administrator for Safety, Reliability, Maintainability, and Quality Assurance stated on December 29, 1986, the intent to retain the NASA standard cell usage policy established by the Office of the Chief Engineer. The current NASA policy is also to incorporate technological advances as they are tested and proven for spaceflight applications. This policy will be implemented by modifying the existing standard cells or by developing new NASA standards and their specifications in accordance with the NASA's Aerospace Battery Systems Program Plan. This NASA Specification for Manufacturing and Performance Requirements of NASA Standard Aerospace Nickel-Cadmium Cells is prepared to provide requirements for the NASA standard nickel-cadmium cell. It is an interim specification pending resolution of the separator material availability. This specification has evolved from over 15 years of nickel-cadmium cell experience by NASA. Consequently, considerable experience has been collected and cell performance has been well characterized from many years of ground testing and from in-flight operations in both geosynchronous (GEO) and low earth orbit (LEO) applications. NASA has developed and successfully used two standard flight qualified cell designs.

  12. 20 CFR 411.375 - Does a State VR agency continue to provide services under the requirements of the State plan...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... approved under title I of the Rehabilitation Act of 1973, as amended (29 U.S.C. 720 et seq.), even when... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Does a State VR agency continue to provide services under the requirements of the State plan approved under title I of the Rehabilitation Act of...

  13. 34 CFR 222.81 - What requirements must a local educational agency meet to be eligible for a payment under section...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false What requirements must a local educational agency meet to be eligible for a payment under section 8003(g) of the Act? 222.81 Section 222.81 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY...

  14. 34 CFR 222.52 - What requirements must a local educational agency meet to receive a payment under section 8003(d)?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false What requirements must a local educational agency meet to receive a payment under section 8003(d)? 222.52 Section 222.52 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY EDUCATION, DEPARTMENT...

  15. 34 CFR 222.91 - What requirements must a local educational agency meet to receive a payment under section 8003 of...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... to receive a payment under section 8003 of the Act for children residing on Indian lands? 222.91 Section 222.91 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY... Educational Agencies That Claim Children Residing on Indian Lands General § 222.91 What requirements must...

  16. Testing Requirements to Manage Data Exchange Specifications in Enterprise Integration - A Schema Design Quality Focus.

    SciTech Connect

    Kulvatunyou, Boonserm; Ivezic, Nenad; Buhwan, Jeong

    2004-07-01

    In this paper, we describe the requirements to test W3C XML Schema usage when defining message schemas for data exchange in any large and evolving enterprise integration project. We then decompose the XML Schema testing into four (4) aspects including the message schema conformance to the XML Schema specification grammar, the message schema conformance to the XML Schema specification semantics, the message schema conformance to design quality testing, and canonical semantics testing of the message schema. We describe these four testing aspects in some detail and point to other related efforts. We further focus to provide some technical details for the message schema design quality testing. As a future work, we describe the requirements for canonical semantics testing and potential solution approaches. Finally, we describe an implementation architecture for the message schema design quality testing.

  17. Benchmark specifications and data requirements for initial modeling of the China experimental fast reactor.

    SciTech Connect

    Fanning, T. H.; Nuclear Engineering Division

    2010-06-04

    A specification is proposed for an initial transient benchmark analysis of the China Experimental Fast Reactor design based on the analysis capabilities of the SAS4A/SASSYS-1 code. For the initial benchmark, a single-channel protected transient overpower accident is defined. Reactivity feedback coefficients will not be required and simplified material properties are recommended. This report also describes the data required for developing the modeling input. This data includes assembly geometry, reactor power distributions, kinetics and decay heat data, and material properties. Comparisons of benchmark results will take place at a future SAS4A/SASSYS-1 training meeting planned to occur at Argonne National Laboratory. Future benchmark specifications will be planned to expand upon this initial model to include more complex reactivity feedback models, material properties, additional assembly geometry, and primary and intermediate coolant systems.

  18. Gamma Ray Observatory (GRO) dynamics simulator requirements and mathematical specifications, revision 1

    NASA Technical Reports Server (NTRS)

    Harman, R.; Blejer, D.

    1990-01-01

    The requirements and mathematical specifications for the Gamma Ray Observatory (GRO) Dynamics Simulator are presented. The complete simulator system, which consists of the profie subsystem, simulation control and input/output subsystem, truth model subsystem, onboard computer model subsystem, and postprocessor, is described. The simulator will be used to evaluate and test the attitude determination and control models to be used on board GRO under conditions that simulate the expected in-flight environment.

  19. Specific requirements of nonbilayer phospholipids in mitochondrial respiratory chain function and formation

    PubMed Central

    Baker, Charli D.; Basu Ball, Writoban; Pryce, Erin N.; Gohil, Vishal M.

    2016-01-01

    Mitochondrial membrane phospholipid composition affects mitochondrial function by influencing the assembly of the mitochondrial respiratory chain (MRC) complexes into supercomplexes. For example, the loss of cardiolipin (CL), a signature non–bilayer-forming phospholipid of mitochondria, results in disruption of MRC supercomplexes. However, the functions of the most abundant mitochondrial phospholipids, bilayer-forming phosphatidylcholine (PC) and non–bilayer-forming phosphatidylethanolamine (PE), are not clearly defined. Using yeast mutants of PE and PC biosynthetic pathways, we show a specific requirement for mitochondrial PE in MRC complex III and IV activities but not for their formation, whereas loss of PC does not affect MRC function or formation. Unlike CL, mitochondrial PE or PC is not required for MRC supercomplex formation, emphasizing the specific requirement of CL in supercomplex assembly. Of interest, PE biosynthesized in the endoplasmic reticulum (ER) can functionally substitute for the lack of mitochondrial PE biosynthesis, suggesting the existence of PE transport pathway from ER to mitochondria. To understand the mechanism of PE transport, we disrupted ER–mitochondrial contact sites formed by the ERMES complex and found that, although not essential for PE transport, ERMES facilitates the efficient rescue of mitochondrial PE deficiency. Our work highlights specific roles of non–bilayer-forming phospholipids in MRC function and formation. PMID:27226479

  20. Entry of Bluetongue Virus Capsid Requires the Late Endosome-specific Lipid Lysobisphosphatidic Acid*

    PubMed Central

    Patel, Avnish; Mohl, Bjorn-Patrick; Roy, Polly

    2016-01-01

    The entry of viruses into host cells is one of the key processes of infection. The mechanisms of cellular entry for enveloped virus have been well studied. The fusion proteins as well as the facilitating cellular lipid factors involved in the viral fusion entry process have been well characterized. The process of non-enveloped virus cell entry, in comparison, remains poorly defined, particularly for large complex capsid viruses of the family Reoviridae, which comprises a range of mammalian pathogens. These viruses enter cells without the aid of a limiting membrane and thus cannot fuse with host cell membranes to enter cells. Instead, these viruses are believed to penetrate membranes of the host cell during endocytosis. However, the molecular mechanism of this process is largely undefined. Here we show, utilizing an in vitro liposome penetration assay and cell biology, that bluetongue virus (BTV), an archetypal member of the Reoviridae, utilizes the late endosome-specific lipid lysobisphosphatidic acid for productive membrane penetration and viral entry. Further, we provide preliminary evidence that lipid lysobisphosphatidic acid facilitates pore expansion during membrane penetration, suggesting a mechanism for lipid factor requirement of BTV. This finding indicates that despite the lack of a membrane envelope, the entry process of BTV is similar in specific lipid requirements to enveloped viruses that enter cells through the late endosome. These results are the first, to our knowledge, to demonstrate that a large non-enveloped virus of the Reoviridae has specific lipid requirements for membrane penetration and host cell entry. PMID:27036941

  1. AMTD: Update of Engineering Specifications Derived from Science Requirements for Future UVOIR Space Telescopes

    NASA Technical Reports Server (NTRS)

    Stahl, H. Philip; Postman, Marc; Mosier, Gary; Smith, W. Scott; Blaurock, Carl; Ha, Kong; Stark, Christopher C.

    2014-01-01

    The Advance Mirror Technology Development (AMTD) project is in Phase 2 of a multiyear effort, initiated in FY12, to mature by at least a half TRL step six critical technologies required to enable 4 meter or larger UVOIR space telescope primary mirror assemblies for both general astrophysics and ultra-high contrast observations of exoplanets. AMTD uses a science-driven systems engineering approach. We mature technologies required to enable the highest priority science AND provide a high-performance low-cost low-risk system. To give the science community options, we are pursuing multiple technology paths. A key task is deriving engineering specifications for advanced normal-incidence monolithic and segmented mirror systems needed to enable both general astrophysics and ultra-high contrast observations of exoplanets missions as a function of potential launch vehicles and their mass and volume constraints. A key finding of this effort is that the science requires an 8 meter or larger aperture telescope

  2. AMTD: update of engineering specifications derived from science requirements for future UVOIR space telescopes

    NASA Astrophysics Data System (ADS)

    Stahl, H. Philip; Postman, Marc; Mosier, Gary; Smith, W. Scott; Blaurock, Carl; Ha, Kong; Stark, Christopher C.

    2014-08-01

    The Advance Mirror Technology Development (AMTD) project is in Phase 2 of a multiyear effort, initiated in FY12, to mature by at least a half TRL step six critical technologies required to enable 4 meter or larger UVOIR space telescope primary mirror assemblies for both general astrophysics and ultra-high contrast observations of exoplanets. AMTD uses a science-driven systems engineering approach. We mature technologies required to enable the highest priority science AND provide a high-performance low-cost low-risk system. To give the science community options, we are pursuing multiple technology paths. A key task is deriving engineering specifications for advanced normal-incidence monolithic and segmented mirror systems needed to enable both general astrophysics and ultra-high contrast observations of exoplanets missions as a function of potential launch vehicles and their mass and volume constraints. A key finding of this effort is that the science requires an 8 meter or larger aperture telescope.

  3. Glia-derived neurons are required for sex-specific learning in C. elegans

    PubMed Central

    Sammut, Michele; Cook, Steven J.; Nguyen, Ken C.Q.; Felton, Terry; Hall, David H.; Emmons, Scott W.

    2015-01-01

    Sex differences in behaviour extend to cognitive-like processes such as learning but the underlying dimorphisms in neural circuit development and organization that generate these behavioural differences are largely unknown. Here we define at the single-cell level, from development, through neural circuit connectivity, to function, the neural basis of a sex-specific learning in the nematode C. elegans. We show that sexual conditioning, a form of associative learning, requires a pair of male-specific interneurons whose progenitors are fully differentiated glia. These neurons are born during sexual maturation and incorporated into pre-exisiting sex-shared circuits to couple chemotactic responses to reproductive priorities. Our findings reveal a general role for glia as neural progenitors across metazoan taxa and demonstrate that the addition of sex-specific neuron types to brain circuits during sexual maturation is an important mechanism for the generation of sexually dimorphic plasticity in learning. PMID:26469050

  4. Glia-derived neurons are required for sex-specific learning in C. elegans.

    PubMed

    Sammut, Michele; Cook, Steven J; Nguyen, Ken C Q; Felton, Terry; Hall, David H; Emmons, Scott W; Poole, Richard J; Barrios, Arantza

    2015-10-15

    Sex differences in behaviour extend to cognitive-like processes such as learning, but the underlying dimorphisms in neural circuit development and organization that generate these behavioural differences are largely unknown. Here we define at the single-cell level-from development, through neural circuit connectivity, to function-the neural basis of a sex-specific learning in the nematode Caenorhabditis elegans. We show that sexual conditioning, a form of associative learning, requires a pair of male-specific interneurons whose progenitors are fully differentiated glia. These neurons are generated during sexual maturation and incorporated into pre-exisiting sex-shared circuits to couple chemotactic responses to reproductive priorities. Our findings reveal a general role for glia as neural progenitors across metazoan taxa and demonstrate that the addition of sex-specific neuron types to brain circuits during sexual maturation is an important mechanism for the generation of sexually dimorphic plasticity in learning.

  5. 49 CFR 178.345 - General design and construction requirements applicable to Specification DOT 406 (§ 178.346), DOT...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false General design and construction requirements... REGULATIONS SPECIFICATIONS FOR PACKAGINGS Specifications for Containers for Motor Vehicle Transportation § 178.345 General design and construction requirements applicable to Specification DOT 406 (§ 178.346),...

  6. Specific immune responses are required to control parasitemia in Babesia equi infection.

    PubMed Central

    Knowles, D P; Kappmeyer, L S; Perryman, L E

    1994-01-01

    Horses possessing a normal immune system and spleen often control infection caused by Babesia equi. However, splenectomized horses are unable to control B. equi infection and usually succumb to the infection. To investigate the role of the spleen in the control of B. equi infection in the absence of specific immune responses, two 1-month-old foals with severe combined immunodeficiency (SCID) and two age-matched normal foals were inoculated with B. equi. The SCID foals became febrile seven days postinoculation and developed terminal parasitemias of 41 and 29%. The SCID foals had greater than 50% decreases in indices of total erythrocytes, packed-cell volumes, and hemoglobin concentrations. Both SCID foals were euthanized in extremis at 10 days postinoculation. As expected, the serum of the SCID foals lacked detectable antibodies to B. equi antigens. In contrast, the normal foals inoculated with B. equi produced detectable anti-erythrocyte-stage parasite antibodies by 7 days and controlled clinical disease by 12 days postinoculation. Although SCID foals lack functional T and B lymphocytes, they do possess complement, macrophages, granulocytes, and natural killer cells, as well as a spleen. Therefore, the data indicate that specific immune responses are required to control B. equi parasitemia but are not required for erythrocyte lysis in infected horses. Furthermore, the spleen is not able to control B. equi parasitemia in the absence of specific immune responses to parasite antigens. Images PMID:8168957

  7. Extraembryonic but not embryonic SUMO-specific protease 2 is required for heart development

    PubMed Central

    Maruyama, Eri O.; Lin, Heng; Chiu, Shang-Yi; Yu, H.-M. Ivy; Porter, George A.; Hsu, Wei

    2016-01-01

    SUMO-specific protease 2 (SENP2) activities to remove SUMO from its substrates is essential for development of trophoblast stem cells, niches and lineages. Global deletion of SENP2 leads to midgestation lethality, and causes severe defects in the placenta which is accompanied by embryonic brain and heart abnormalities. Because of the placental deficiencies, the role of SENP2 in development of the embryonic tissues has not been properly determined. The brain and heart abnormalities may be secondary to placental insufficiency. Here we have created a new mouse strain permitting conditional inactivation of SENP2. Mice homozygous for germline deletion of the conditional allele exhibit trophoblast defects and embryonic abnormalities resembling the global SENP2 knockout. However, tissue-specific disruptions of SENP2 demonstrate its dispensable role in embryogenesis. Placental expression of SENP2 is necessary and sufficient for embryonic heart and brain development. Using a protease deficient model, we further demonstrate the requirement of SENP2-dependent SUMO modification in development of all major trophoblast lineages. SENP2 regulates sumoylation of Mdm2 which controls p53 activities critical for G-S transition of mitotic division and endoreduplication in trophoblast proliferation and differentiation, respectively. The differentiation of trophoblasts is also dependent on SENP2-mediated activation of p57Kip2, a CDK-specific inhibitor required for endoreduplication. PMID:26883797

  8. 22 CFR 210.645 - Federal agency or agency.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Federal agency or agency. 210.645 Section 210.645 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 210.645 Federal agency or agency. Federal agency or...

  9. 22 CFR 210.645 - Federal agency or agency.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Federal agency or agency. 210.645 Section 210.645 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 210.645 Federal agency or agency. Federal agency or...

  10. 22 CFR 312.645 - Federal agency or agency.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Federal agency or agency. 312.645 Section 312.645 Foreign Relations PEACE CORPS GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 312.645 Federal agency or agency. Federal agency or agency means any United...

  11. 22 CFR 312.645 - Federal agency or agency.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Federal agency or agency. 312.645 Section 312.645 Foreign Relations PEACE CORPS GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 312.645 Federal agency or agency. Federal agency or agency means any United...

  12. 22 CFR 312.645 - Federal agency or agency.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Federal agency or agency. 312.645 Section 312.645 Foreign Relations PEACE CORPS GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 312.645 Federal agency or agency. Federal agency or agency means any United...

  13. 41 CFR 102-74.350 - Are agencies required to meet their obligations under the Federal Service Labor-Management...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... exclusive representative for the employees prior to implementing this smoking policy? 102-74.350 Section 102... (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Smoking... smoking policy? Yes. Where there is an exclusive representative for the employees, Federal agencies...

  14. 41 CFR 102-74.350 - Are agencies required to meet their obligations under the Federal Service Labor-Management...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... exclusive representative for the employees prior to implementing this smoking policy? 102-74.350 Section 102... (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Smoking... smoking policy? Yes. Where there is an exclusive representative for the employees, Federal agencies...

  15. 41 CFR 102-74.350 - Are agencies required to meet their obligations under the Federal Service Labor-Management...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... exclusive representative for the employees prior to implementing this smoking policy? 102-74.350 Section 102... (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Smoking... smoking policy? Yes. Where there is an exclusive representative for the employees, Federal agencies...

  16. 41 CFR 102-74.350 - Are agencies required to meet their obligations under the Federal Service Labor-Management...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... exclusive representative for the employees prior to implementing this smoking policy? 102-74.350 Section 102... (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Smoking... smoking policy? Yes. Where there is an exclusive representative for the employees, Federal agencies...

  17. 41 CFR 102-74.350 - Are agencies required to meet their obligations under the Federal Service Labor-Management...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... exclusive representative for the employees prior to implementing this smoking policy? 102-74.350 Section 102... (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Smoking... smoking policy? Yes. Where there is an exclusive representative for the employees, Federal agencies...

  18. 5 CFR 792.219 - Are agencies required to negotiate with their Federal labor organizations concerning the...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... their Federal labor organizations concerning the implementation of this law? 792.219 Section 792.219... EMPLOYEES' HEALTH AND COUNSELING PROGRAMS Agency Use of Appropriated Funds for Child Care Costs for Lower Income Employees-What Is the Child Care Subsidy Program Legislation and to Whom Does It Apply? §...

  19. 5 CFR 595.103 - What requirements must agencies establish for determining which physician positions are covered?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... research and experimental work, including the conduct of medical work pertaining to food, drugs, cosmetics, and devices (or the review or evaluation of such medical research and experimental work), or the... medical research and experimental programs. (c) The agency head may establish as separate categories...

  20. 5 CFR 595.103 - What requirements must agencies establish for determining which physician positions are covered?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... research and experimental work, including the conduct of medical work pertaining to food, drugs, cosmetics, and devices (or the review or evaluation of such medical research and experimental work), or the... medical research and experimental programs. (c) The agency head may establish as separate categories...

  1. 5 CFR 595.103 - What requirements must agencies establish for determining which physician positions are covered?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... research and experimental work, including the conduct of medical work pertaining to food, drugs, cosmetics, and devices (or the review or evaluation of such medical research and experimental work), or the... medical research and experimental programs. (c) The agency head may establish as separate categories...

  2. 5 CFR 595.103 - What requirements must agencies establish for determining which physician positions are covered?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... research and experimental work, including the conduct of medical work pertaining to food, drugs, cosmetics, and devices (or the review or evaluation of such medical research and experimental work), or the... medical research and experimental programs. (c) The agency head may establish as separate categories...

  3. 5 CFR 595.103 - What requirements must agencies establish for determining which physician positions are covered?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... research and experimental work, including the conduct of medical work pertaining to food, drugs, cosmetics, and devices (or the review or evaluation of such medical research and experimental work), or the... medical research and experimental programs. (c) The agency head may establish as separate categories...

  4. Specifications of the octupole magnets required for the ATF2 ultra-low ß* lattice

    SciTech Connect

    Marin, E.; Modena, M.; Tauchi, T.; Terunuma, N.; Tomas, R.; White, G.R.; /SLAC

    2014-05-28

    The Accelerator Test Facility 2 (ATF2) aims to test the novel chromaticity correction for higher chromaticity lattices as the one of CLIC. To this end the ATF2 ultra-low ß* lattice is designed to vertically focus the beam at the focal point or usually referred to as interaction point (IP), down to 23 nm. However when the measured multipole components of the ATF2 magnets are considered in the simulations, the evaluated spot sizes at the IP are well above the design value. The designed spot size is effectively recovered by inserting a pair of octupole magnets. In this note we address the technical specifications required for these octupole magnets.

  5. Arx is required for specification of the zona incerta and reticular nucleus of the thalamus

    PubMed Central

    Sunnen, C. Nicole; Simonet, Jacqueline C.; Marsh, Eric D.; Golden, Jeffrey A.

    2014-01-01

    Mutations in the aristaless-related homeobox (ARX) gene result in a spectrum of structural and functional nervous system disorders including lissencephaly, movement disorders, intellectual disabilities, and epilepsy. Some patients also have symptoms indicative of hypothalamic dysfunction, however, little is known about the role of ARX in diencephalic development. To begin evaluating diencephalic defects we examined the expression of a panel of known genes and gene products that label specific diencephalic nuclei in two different Arx mutant mouse lines. Male mice engineered to have a polyalanine expansion mutation (Arx(GCG)7/Y) revealed no expression differences in any diencephalic nucleus when compared to wildtype littermates. In contrast, mice null for Arx (Arx−/Y) lost expression of specific markers of the thalamic reticular nucleus (TRN) and zona incerta (ZI), while retaining expression in other thalamic nuclei and in the hypothalamus. Tyrosine hydroxylase, a marker of the ZI’s dopaminergic A13 sub-nucleus, was among those lost, suggesting a requirement for Arx in normal TRN and ZI development, and for A13 dopaminergic fate, specifically. Since the ZI and A13 regions make connections to several hypothalamic nuclei, such mis-specification may contribute to the “hypothalamic dysfunction” observed in some patients. PMID:24487799

  6. Maternal Dead-End1 is required for vegetal cortical microtubule assembly during Xenopus axis specification

    PubMed Central

    Mei, Wenyan; Jin, Zhigang; Lai, Fangfang; Schwend, Tyler; Houston, Douglas W.; King, Mary Lou; Yang, Jing

    2013-01-01

    Vertebrate axis specification is an evolutionarily conserved developmental process that relies on asymmetric activation of Wnt signaling and subsequent organizer formation on the future dorsal side of the embryo. Although roles of Wnt signaling during organizer formation have been studied extensively, it is unclear how the Wnt pathway is asymmetrically activated. In Xenopus and zebrafish, the Wnt pathway is triggered by dorsal determinants, which are translocated from the vegetal pole to the future dorsal side of the embryo shortly after fertilization. The transport of dorsal determinants requires a unique microtubule network formed in the vegetal cortex shortly after fertilization. However, molecular mechanisms governing the formation of vegetal cortical microtubule arrays are not fully understood. Here we report that Dead-End 1 (Dnd1), an RNA-binding protein required for primordial germ cell development during later stages of embryogenesis, is essential for Xenopus axis specification. We show that knockdown of maternal Dnd1 specifically interferes with the formation of vegetal cortical microtubules. This, in turn, impairs translocation of dorsal determinants, the initiation of Wnt signaling, organizer formation, and ultimately results in ventralized embryos. Furthermore, we found that Dnd1 binds to a uridine-rich sequence in the 3′-UTR of trim36, a vegetally localized maternal RNA essential for vegetal cortical microtubule assembly. Dnd1 anchors trim36 to the vegetal cortex in the egg, promoting high concentrations of Trim36 protein there. Our work thus demonstrates a novel and surprising function for Dnd1 during early development and provides an important link between Dnd1, mRNA localization, the microtubule cytoskeleton and axis specification. PMID:23615278

  7. Neurotransmitter Transporter-Like: A Male Germline-specific SLC6 Transporter Required for Drosophila Spermiogenesis

    PubMed Central

    Chatterjee, Nabanita; Rollins, Janet; Mahowald, Anthony P.; Bazinet, Christopher

    2011-01-01

    The SLC6 class of membrane transporters, known primarily as neurotransmitter transporters, is increasingly appreciated for its roles in nutritional uptake of amino acids and other developmentally specific functions. A Drosophila SLC6 gene, Neurotransmitter transporter-like (Ntl), is expressed only in the male germline. Mobilization of a transposon inserted near the 3′ end of the Ntl coding region yields male-sterile mutants defining a single complementation group. Germline transformation with Ntl cDNAs under control of male germline-specific control elements restores Ntl/Ntl homozygotes to normal fertility, indicating that Ntl is required only in the germ cells. In mutant males, sperm morphogenesis appears normal, with elongated, individualized and coiled spermiogenic cysts accumulating at the base of the testes. However, no sperm are transferred to the seminal vesicle. The level of polyglycylation of Ntl mutant sperm tubulin appears to be significantly lower than that of wild type controls. Glycine transporters are the most closely related SLC6 transporters to Ntl, suggesting that Ntl functions as a glycine transporter in developing sperm, where augmentation of the cytosolic pool of glycine may be required for the polyglycylation of the massive amounts of tubulin in the fly's giant sperm. The male-sterile phenotype of Ntl mutants may provide a powerful genetic system for studying the function of an SLC6 transporter family in a model organism. PMID:21298005

  8. Neural crest specification and migration independently require NSD3-related lysine methyltransferase activity

    PubMed Central

    Jacques-Fricke, Bridget T.; Gammill, Laura S.

    2014-01-01

    Neural crest precursors express genes that cause them to become migratory, multipotent cells, distinguishing them from adjacent stationary neural progenitors in the neurepithelium. Histone methylation spatiotemporally regulates neural crest gene expression; however, the protein methyltransferases active in neural crest precursors are unknown. Moreover, the regulation of methylation during the dynamic process of neural crest migration is unclear. Here we show that the lysine methyltransferase NSD3 is abundantly and specifically expressed in premigratory and migratory neural crest cells. NSD3 expression commences before up-regulation of neural crest genes, and NSD3 is necessary for expression of the neural plate border gene Msx1, as well as the key neural crest transcription factors Sox10, Snail2, Sox9, and FoxD3, but not gene expression generally. Nevertheless, only Sox10 histone H3 lysine 36 dimethylation requires NSD3, revealing unexpected complexity in NSD3-dependent neural crest gene regulation. In addition, by temporally limiting expression of a dominant negative to migratory stages, we identify a novel, direct requirement for NSD3-related methyltransferase activity in neural crest migration. These results identify NSD3 as the first protein methyltransferase essential for neural crest gene expression during specification and show that NSD3-related methyltransferase activity independently regulates migration. PMID:25318671

  9. eor-1 and eor-2 are required for cell-specific apoptotic death in C. elegans.

    PubMed

    Hoeppner, Daniel J; Spector, Mona S; Ratliff, Thomas M; Kinchen, Jason M; Granat, Susan; Lin, Shih-Chieh; Bhusri, Satjit S; Conradt, Barbara; Herman, Michael A; Hengartner, Michael O

    2004-10-01

    Programmed cell death occurs in every multicellular organism and in diverse cell types yet the genetic controls that define which cells will live and which will die remain poorly understood. During development of the nematode Caenorhabditis elegans, the coordinated activity of four gene products, EGL-1, CED-9, CED-4 and CED-3, results in the death of essentially all cells fated to die. To identify novel upstream components of the cell death pathway, we performed a genetic screen for mutations that abolish the death of the hermaphrodite-specific neurons (HSNs), a homologous pair of cells required for egg-laying in the hermaphrodite. We identified and cloned the genes, eor-1 and eor-2, which are required to specify the fate of cell death in male HSNs. In addition to defects in HSN death, mutation of either gene leads to defects in coordinated movement, neuronal migration, male tail development, and viability; all consistent with abnormal neuronal differentiation. eor-1 encodes a putative transcription factor related to the human oncogene PLZF. eor-2 encodes a novel but conserved protein. We propose that eor-1 and eor-2 function together throughout the nervous system to promote terminal differentiation of neurons and function specifically in male HSNs to promote apoptotic death of the HSNs.

  10. The efficacy of pneumococcal capsular polysaccharide-specific antibodies to serotype 3 Streptococcus pneumoniae requires macrophages.

    PubMed

    Fabrizio, Kevin; Manix, Catherine; Tian, Haijun; van Rooijen, Nico; Pirofski, Liise-anne

    2010-11-03

    The efficacy of antibody immunity against Streptococcus pneumoniae stems from the ability of opsonic, serotype (ST)-specific antibodies to pneumococcal capsular polysaccharide (PPS) to facilitate killing of the homologous ST by host phagocytes. However, PPS-specific antibodies have been identified that are protective in mice, but do not promote opsonic killing in vitro, raising the question of how they mediate protection in vivo. To probe this question, we investigated the dependence of antibody efficacy against lethal systemic (intraperitoneal, i.p.) infection with Streptococcus pneumoniae serotype 3 (ST3) on macrophages and neutrophils for the following PPS3-specific monoclonal antibodies (MAbs) in survival experiments in mice using a non-opsonic human IgM (A7), a non-opsonic mouse IgG1 (1E2) and an opsonic mouse IgG1 (5F6). The survival of A7- and PPS3-specific and isotype control MAb-treated neutrophil-depleted and neutrophil-sufficient and macrophage-depleted and macrophage-sufficient mice were determined after i.p. challenge with ST3 strains 6303 and WU2. Neutrophils were dispensable for A7 and the mouse MAbs to mediate protection in this model, but macrophages were required for the efficacy of A7 and optimal mouse MAb-mediated protection. For A7-treated mice, macrophage-depleted mice had higher blood CFU, cytokines and peripheral neutrophil levels than macrophage-sufficient mice, and macrophage-sufficient mice had lower tissue bacterial burdens than control MAb-treated mice. These findings demonstrate that macrophages contribute to opsonic and non-opsonic PPS3-specific MAb-mediated protection against ST3 infection by enhancing bacterial clearance and suggest that neutrophils do not compensate for the absence of macrophages in the model used in this study.

  11. Federal technology transfer requirements :a focused study of principal agencies approaches with implications for the Department of Homeland Security.

    SciTech Connect

    Koker, Denise; Micheau, Jill M.

    2006-07-01

    This report provides relevant information and analysis to the Department of Homeland Security (DHS) that will assist DHS in determining how to meet the requirements of federal technology transfer legislation. These legal requirements are grouped into five categories: (1) establishing an Office of Research and Technology Applications, or providing the functions thereof; (2) information management; (3) enabling agreements with non-federal partners; (4) royalty sharing; and (5) invention ownership/obligations. These five categories provide the organizing framework for this study, which benchmarks other federal agencies/laboratories engaged in technology transfer/transition Four key agencies--the Department of Health & Human Services (HHS), the U.S. Department of Agriculture (USDA), the Department of Energy (DOE), and the Department of Defense (DoD)--and several of their laboratories have been surveyed. An analysis of DHS's mission needs for commercializing R&D compared to those agencies/laboratories is presented with implications and next steps for DHS's consideration. Federal technology transfer legislation, requirements, and practices have evolved over the decades as agencies and laboratories have grown more knowledgeable and sophisticated in their efforts to conduct technology transfer and as needs and opinions in the federal sector have changed with regards to what is appropriate. The need to address requirements in a fairly thorough manner has, therefore, resulted in a lengthy paper. There are two ways to find summary information. Each chapter concludes with a summary, and there is an overall ''Summary and Next Steps'' chapter on pages 57-60. For those readers who are unable to read the entire document, we recommend referring to these pages.

  12. An Automated Method for Identifying Inconsistencies within Diagrammatic Software Requirements Specifications

    NASA Technical Reports Server (NTRS)

    Zhang, Zhong

    1997-01-01

    The development of large-scale, composite software in a geographically distributed environment is an evolutionary process. Often, in such evolving systems, striving for consistency is complicated by many factors, because development participants have various locations, skills, responsibilities, roles, opinions, languages, terminology and different degrees of abstraction they employ. This naturally leads to many partial specifications or viewpoints. These multiple views on the system being developed usually overlap. From another aspect, these multiple views give rise to the potential for inconsistency. Existing CASE tools do not efficiently manage inconsistencies in distributed development environment for a large-scale project. Based on the ViewPoints framework the WHERE (Web-Based Hypertext Environment for requirements Evolution) toolkit aims to tackle inconsistency management issues within geographically distributed software development projects. Consequently, WHERE project helps make more robust software and support software assurance process. The long term goal of WHERE tools aims to the inconsistency analysis and management in requirements specifications. A framework based on Graph Grammar theory and TCMJAVA toolkit is proposed to detect inconsistencies among viewpoints. This systematic approach uses three basic operations (UNION, DIFFERENCE, INTERSECTION) to study the static behaviors of graphic and tabular notations. From these operations, subgraphs Query, Selection, Merge, Replacement operations can be derived. This approach uses graph PRODUCTIONS (rewriting rules) to study the dynamic transformations of graphs. We discuss the feasibility of implementation these operations. Also, We present the process of porting original TCM (Toolkit for Conceptual Modeling) project from C++ to Java programming language in this thesis. A scenario based on NASA International Space Station Specification is discussed to show the applicability of our approach. Finally

  13. Bacteriophage SPP1 pac Cleavage: A Precise Cut without Sequence Specificity Requirement.

    PubMed

    Djacem, Karima; Tavares, Paulo; Oliveira, Leonor

    2017-01-09

    In many tailed bacteriophages, DNA packaging is initiated by recognition and cleavage of a specific sequence pac by the small (TerS) and large (TerL) terminase subunits. It was previously shown that the SPP1 pac region has two sequences where TerS binds (pacR and pacL), flanking the segment where TerL cleaves the SPP1 DNA (pacC). However, the pac-specific sequences required to achieve this endonucleolytic cut were not established. Their characterization is essential to understand the underlying mechanism. We show that the pacR sequence localized within 35bp downstream of the pac cut can be extensively degenerated, including its c1 and c2 repeats, and that only a disruption of a 5-bp polyadenine tract impairs the pac cleavage. This result together with deletion analysis of pacL shows that the specific DNA sequences required for targeting the terminase for pac cleavage are considerably shorter than the large region bound by TerS. Furthermore, extensive degeneration of the 6-bp target sequence within pacC where pac cleavage occurs reveals that TerL maintains, remarkably, its precise position of cleavage. Studies with SPP1-related phages show the conservation of the cut position, irrespective of the sequence variation in pacC and in pacR or the changes in pacL-pacC distance. Mechanistically, our data are compatible with a model in which TerS interactions with part of the pacL sequence and a poly-A tract in pacR are sufficient to orient very accurately the TerL nuclease to a defined pacC position. They also demonstrate that the resulting precise cut at pacC is independent of the targeted DNA sequence.

  14. Stage specific requirement of Gfrα1 in the ureteric epithelium during kidney development.

    PubMed

    Keefe Davis, T; Hoshi, Masato; Jain, Sanjay

    2013-01-01

    Glial cell line-derived neurotrophic factor (GDNF) binds a coreceptor GDNF family receptor α1 (GFRα1) and forms a signaling complex with the receptor tyrosine kinase RET. GDNF-GFRα1-RET signaling activates cellular pathways that are required for normal induction of the ureteric bud (UB) from the Wolffian duct (WD). Failure of UB formation results in bilateral renal agenesis and perinatal lethality. Gfrα1 is expressed in both the epithelial and mesenchymal compartments of the developing kidney while Ret expression is specific to the epithelium. The biological importance of Gfrα1's wider tissue expression and its role in later kidney development are unclear. We discovered that conditional loss of Gfrα1 in the WD epithelium prior to UB branching is sufficient to cause renal agenesis. This finding indicates that Gfrα1 expressed in the nonepithelial structures cannot compensate for this loss. To determine Gfrα1's role in branching morphogenesis after UB induction we used an inducible Gfrα1-specific Cre-deletor strain and deleted Gfrα1 from the majority of UB tip cells post UB induction in vivo and in explant kidney cultures. We report that Gfrα1 excision from the epithelia compartment after UB induction caused a modest reduction in branching morphogenesis. The loss of Gfrα1 from UB-tip cells resulted in reduced cell proliferation and decreased activated ERK (pERK). Further, cells without Gfrα1 expression are able to populate the branching UB tips. These findings delineate previously unclear biological roles of Gfrα1 in the urinary tract and demonstrate its cell-type and stage-specific requirements in kidney development.

  15. Proliferation Security Initiative: Agencies Have Adopted Policies and Procedures but Steps Needed to Meet Reporting Requirement and to Measure Results

    DTIC Science & Technology

    2012-03-01

    Participation, Fiscal Years 2009-2011 12 Figure Figure 1: Sample Logic Model 18 Abbreviations 9/11 Act Implementing Recommendations of the 9/11...has previously identified such frameworks, called logic models , that agencies could adopt even if they face performance measurement challenges similar...31A logic model is an evaluation tool used to describe a program’s—or initiative’s, in the case of PSI—components and

  16. Sensitivity requirements of assisted BDS and GPS in specification 3GPP TS 36.171

    NASA Astrophysics Data System (ADS)

    Jin, Xiaoxi; Chen, Xin; Ying, Rendong; Yang, Genke

    2016-01-01

    With the needs of growing location-based service, a more high-performance satellite positioning technology - assisted global navigation satellite system (A-GNSS assisted-GNSS) becomes a new hotspot in area of navigation and positioning. Now, 3GPP has already provided supports for GPS, Galileo, GLONASS and QZSS, SBAS, so standardization work of introduction BDS into 3GPP organization is very imperative. In this paper, we first analysis the performance of GPS L1 C/A with assistant information, then by taking into account the difference between BDS and GPS, including the unique nature of GEO/NGEO satellites' navigation message data length and format, we design the sensitivity requirements of BDS B1 following A-GPS. The results between A-GPS and A-BDS of typical sensitivity test cases are shown in this paper, which show that the suggested sensitivity requirements satisfy the minimum performance requirements under technical specification of 3GPP TS 36.171.

  17. Australin: a chromosomal passenger protein required specifically for Drosophila melanogaster male meiosis

    PubMed Central

    Gao, Shan; Giansanti, Maria Grazia; Buttrick, Graham J.; Ramasubramanyan, Sharada; Auton, Adam; Gatti, Maurizio; Wakefield, James G.

    2008-01-01

    The chromosomal passenger complex (CPC), which is composed of conserved proteins aurora B, inner centromere protein (INCENP), survivin, and Borealin/DASRA, localizes to chromatin, kinetochores, microtubules, and the cell cortex in a cell cycle–dependent manner. The CPC is required for multiple aspects of cell division. Here we find that Drosophila melanogaster encodes two Borealin paralogues, Borealin-related (Borr) and Australin (Aust). Although Borr is a passenger in all mitotic tissues studied, it is specifically replaced by Aust for the two male meiotic divisions. We analyzed aust mutant spermatocytes to assess the effects of fully inactivating the Aust-dependent functions of the CPC. Our results indicate that Aust is required for sister chromatid cohesion, recruitment of the CPC to kinetochores, and chromosome alignment and segregation but not for meiotic histone phosphorylation or spindle formation. Furthermore, we show that the CPC is required earlier in cytokinesis than previously thought; cells lacking Aust do not initiate central spindle formation, accumulate anillin or actin at the cell equator, or undergo equatorial constriction. PMID:18268101

  18. Specific immunoadsorption of pathogenic autoantibodies in pemphigus requires the entire ectodomains of desmogleins.

    PubMed

    Langenhan, Jana; Dworschak, Jenny; Saschenbrecker, Sandra; Komorowski, Lars; Schlumberger, Wolfgang; Stöcker, Winfried; Westermann, Jürgen; Recke, Andreas; Zillikens, Detlef; Schmidt, Enno; Probst, Christian

    2014-04-01

    Pemphigus foliaceus (PF) and pemphigus vulgaris (PV) are life-threatening autoimmune blistering skin diseases. They are characterized by circulating autoantibodies which bind to the ectodomains of desmoglein (Dsg) 1 and Dsg3. These antibodies induce acantholysis in skin and mucous membranes. In severe cases of pemphigus, immunoadsorption is applied to remove total IgG from patient plasma using protein A or other ligands. To develop a specific adsorber for anti-Dsg antibodies, epitope mapping studies of Dsg1 and Dsg3 ectodomains were conducted. Dsg variants were expressed on the surface of HEK-293 cells and analysed for reactivity with pemphigus and control sera by indirect immunofluorescence technique. For Dsg1, a construct consisting of domain 1 directly fused to domain 5, seemed to be suitable for specific immunoadsorption of anti-Dsg1 antibodies. The recognized epitopes were mainly conformation-dependent. However, adsorption of pemphigus foliaceus IgG using this protein coupled to a Sepharose matrix did not completely remove pathogenicity from the sera, as proven by a keratinocyte dissociation assay. In contrast, full-length Dsg1 and Dsg3 ectodomains were able to specifically adsorb anti-Dsg antibodies and to efficiently eliminate pathogenicity. Therefore, the complete and correctly folded ectodomains of both desmogleins are required for therapeutic immunoadsorption.

  19. Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling.

    PubMed

    Sena, Laura A; Li, Sha; Jairaman, Amit; Prakriya, Murali; Ezponda, Teresa; Hildeman, David A; Wang, Chyung-Ru; Schumacker, Paul T; Licht, Jonathan D; Perlman, Harris; Bryce, Paul J; Chandel, Navdeep S

    2013-02-21

    It is widely appreciated that T cells increase glycolytic flux during activation, but the role of mitochondrial flux is unclear. Here, we have shown that mitochondrial metabolism in the absence of glucose metabolism is sufficient to support interleukin-2 (IL-2) induction. Furthermore, we used mice with reduced mitochondrial reactive oxygen species (mROS) production in T cells (T-Uqcrfs(-/-) mice) to show that mitochondria are required for T cell activation to produce mROS for activation of nuclear factor of activated T cells (NFAT) and subsequent IL-2 induction. These mice could not induce antigen-specific expansion of T cells in vivo, but Uqcrfs1(-/-) T cells retained the ability to proliferate in vivo under lymphopenic conditions. This suggests that Uqcrfs1(-/-) T cells were not lacking bioenergetically but rather lacked specific ROS-dependent signaling events needed for antigen-specific expansion. Thus, mitochondrial metabolism is a critical component of T cell activation through the production of complex III ROS.

  20. Metamorphic T3-response genes have specific co-regulator requirements

    PubMed Central

    Havis, Emmanuelle; Sachs, Laurent M.; Demeneix, Barbara A.

    2003-01-01

    Thyroid hormone receptors (TRs) have several regulatory functions in vertebrates. In the absence of thyroid hormone (T3; triiodothyronine), apo-TRs associate with co-repressors to repress transcription, whereas in the presence of T3, holo-TRs engage transcriptional coactivators. Although many studies have addressed the molecular mechanisms of T3 action, it is not known how specific physiological responses arise. We used T3-dependent amphibian metamorphosis to analyse how TRs interact with particular co-regulators to differentially regulate gene expression during development. Using chromatin immunoprecipitation to study tissue from pre-metamorphic tad-poles, we found that TRs are physically associated with T3-responsive promoters, whether or not T3 is present. Addition of T3 results in histone H4 acetylation specifically on T3-response genes. Most importantly, we show that individual T3-response genes have distinct co-regulator requirements, the T3-dependent co-repressor-to-coactivator switch being gene-specific for both co-regulator categories. PMID:12947412