Science.gov

Sample records for aggregate labor productivity

  1. Teaching Keynes's Principle of Effective Demand Using the Aggregate Labor Market Diagram.

    ERIC Educational Resources Information Center

    Dalziel, Paul; Lavoie, Marc

    2003-01-01

    Suggests a method to teach John Keynes's principle of effective demand using a standard aggregate labor market diagram familiar to students taking advanced undergraduate macroeconomics courses. States the analysis incorporates Michal Kalecki's version to show Keynesian unemployment as a point on the aggregate labor demand curve inside the…

  2. 77 FR 9267 - Child Labor, Forced Labor, and Forced or Indentured Child Labor in the Production of Goods in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR Child Labor, Forced Labor, and Forced or Indentured Child Labor in the Production of Goods in Foreign Countries and Efforts by Certain Countries To Eliminate the Worst Forms of Child Labor AGENCY: The Bureau...

  3. Labor Productivity Distribution with Negative Temperature

    NASA Astrophysics Data System (ADS)

    Iyetomi, H.

    Exhaustive financial data of firms in Japan enables us to shed light on how the labor productivity, defined here as value added produced by one worker in a year, is diverse across firms and workers. Statistical equilibrium theory reinforced with the concept of negative temperature turns out to be useful to explain the empirical facts on a major part of the distribution of workers over labor productivity states, where particle and single-particle energy are replaced by worker and labor productivity, respectively. The zero-temperature state in the negative temperature regime corresponds to the optimized state for the current mainstream economics, where all workers are allocated to a state of the highest productivity. Significant difference in temperature is observed between the manufacturing and nonmanufacturing sectors. The negative temperature in the nonmanufacturing sector is three times lower than that in the manufacturing sector, indicating that the former may suffer from a much wider demand gap. In contrast, the two sectors are almost in equilibrium with respect to exchange of workers.

  4. A look at construction aggregates production

    USGS Publications Warehouse

    Willett, Jason Christopher

    2009-01-01

    Construction aggregates are defined as the combination of crushed stone and construction sand and gravel. Aggregates are one of the most accessible natural resources on Earth and one of the fundamental building blocks of our society. They have been used from the earliest times of our civilization for a variety of applications that have increased in number and complexity with time and technological progress. Despite the relatively low but increasing unit value of its basic products, the construction aggregates industry is a major contributor to and an indicator of the economic well-being of the nation.

  5. Production of prone-to-aggregate proteins.

    PubMed

    Lebendiker, Mario; Danieli, Tsafi

    2014-01-21

    Expression of recombinant proteins in Escherichia coli (E. coli) remains the most popular and cost-effective method for producing proteins in basic research and for pharmaceutical applications. Despite accumulating experience and methodologies developed over the years, production of recombinant proteins prone to aggregate in E. coli-based systems poses a major challenge in most research applications. The challenge of manufacturing these proteins for pharmaceutical applications is even greater. This review will discuss effective methods to reduce and even prevent the formation of aggregates in the course of recombinant protein production. We will focus on important steps along the production path, which include cloning, expression, purification, concentration, and storage. PMID:24211444

  6. Labor productivity in heavy construction: impact on synfuels program employment

    SciTech Connect

    Kusterer, K.C.

    1980-06-01

    This study focuses on variations in labor productivity in the heavy construction industry. Productivity is one of a number of factors likely to affect the speed and cost of constructing a synthetic fuels plant. The findings of this study are presented with reference to synthetic fuels plants, but they are relevant to other large energy facilities as well. The data were gathered through a detailed literature search and extensive in-depth interviews with consultants in heavy industrial construction, union officials, and management. In this manner the most important determinants of labor productivity were identified and ranked in terms of relative significance. The type of project under construction is the most important factor affecting the productivity of heavy construction labor. Projects characterized by the utility work syndrome are large, complex, relatively unique, highly regulated, and have cost-plus contracts and tight deadlines. Such projects generally have lower-than-average levels of labor productivity. Labor productivity is also lowered by worker and management morale problems, due to delays and design changes, and by high levels of unemployment among construction workers. Finally, boom town conditions, caused by workers moving to live near large projects located in rural areas, also are likely to result in below-average labor productivity.Synthetic fuels plants are likely to have a number of these identified characteristics. Consequently, the findings suggest that labor productivity may well be a problem for the timely development of an economically competitive synthetic fuels industry.

  7. 76 FR 22921 - Child Labor, Forced Labor, and Forced or Indentured Child Labor in the Production of Goods in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-25

    ... Labor and Human Trafficking (OCFT) at the e-mail or physical address below by 5 p.m., May 20, 2011. To... goods (72 FR 73374). The guidelines set forth the criteria by which information is evaluated... of products (the ``List''), identified by country of origin, that the Department, in consultation...

  8. Health sector employment growth calls for improvements in labor productivity.

    PubMed

    Hofmarcher, Maria M; Festl, Eva; Bishop-Tarver, Leslie

    2016-08-01

    While rising costs of healthcare have put increased fiscal pressure on public finance, job growth in the health sector has had a stabilizing force on overall employment levels - not least in times of economic crises. In 2014 EU-15 countries employed 21 million people in the health and social care sector. Between 2000 and 2014 the share of employed persons in this sector rose from 9.5% to 12.5% of the total labor force in EU-15 countries. Over time labor input growth has shifted towards residential care activities and social work while labor in human health activities including hospitals and ambulatory care still comprises the major share. About half of the human health labor force works in hospital. Variation of health and social care employment is large even in countries with generally comparable institutional structures. While standard measures of productivity in health and social care are not yet comparable across countries, we argue that labor productivity of a growing health work force needs more attention. The long-term stability of the health system will require care delivery models that better utilize a growing health work force in concert with smart investments in digital infrastructure to support this transition. In light of this, more research is needed to explain variations in health and social care labor endowments, to identify effective policy measures of labor productivity enhancement including enhanced efforts to develop comparable productivity indicators in these areas.

  9. Health sector employment growth calls for improvements in labor productivity.

    PubMed

    Hofmarcher, Maria M; Festl, Eva; Bishop-Tarver, Leslie

    2016-08-01

    While rising costs of healthcare have put increased fiscal pressure on public finance, job growth in the health sector has had a stabilizing force on overall employment levels - not least in times of economic crises. In 2014 EU-15 countries employed 21 million people in the health and social care sector. Between 2000 and 2014 the share of employed persons in this sector rose from 9.5% to 12.5% of the total labor force in EU-15 countries. Over time labor input growth has shifted towards residential care activities and social work while labor in human health activities including hospitals and ambulatory care still comprises the major share. About half of the human health labor force works in hospital. Variation of health and social care employment is large even in countries with generally comparable institutional structures. While standard measures of productivity in health and social care are not yet comparable across countries, we argue that labor productivity of a growing health work force needs more attention. The long-term stability of the health system will require care delivery models that better utilize a growing health work force in concert with smart investments in digital infrastructure to support this transition. In light of this, more research is needed to explain variations in health and social care labor endowments, to identify effective policy measures of labor productivity enhancement including enhanced efforts to develop comparable productivity indicators in these areas. PMID:27370916

  10. Labor Productivity Standards in Texas School Foodservice Operations

    ERIC Educational Resources Information Center

    Sherrin, A. Rachelle; Bednar, Carolyn; Kwon, Junehee

    2009-01-01

    Purpose: Purpose of this research was to investigate utilization of labor productivity standards and variables that affect productivity in Texas school foodservice operations. Methods: A questionnaire was developed, validated, and pilot tested, then mailed to 200 randomly selected Texas school foodservice directors. Descriptive statistics for…

  11. International Trends in Productivity and Labor Costs.

    ERIC Educational Resources Information Center

    Capdevielle, Patricia; And Others

    1982-01-01

    Productivity increased in 1981 in the United States, Japan, and European countries studied. Gains ranged from 2 to 4 percent in the US, Japan, France, Germany, Italy, and the Netherlands, to 6 percent in England and Denmark, and more than 7 percent in Belgium. In Canada and Sweden, productivity remained essentially unchanged. (SSH)

  12. Labor.

    ERIC Educational Resources Information Center

    Martz, Carlton

    2001-01-01

    This theme issue of the "Bill of Rights in Action" looks at labor issues. The first article examines the unionization efforts of the Wobblies in the United States at the beginning of the 20th century. The second article explores the protests of the Luddites during Britain's Industrial Revolution. The final article looks at whether international…

  13. 21 CFR 1303.11 - Aggregate production quotas.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Aggregate production quotas. 1303.11 Section 1303.11 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE QUOTAS Aggregate Production... manufacturing and for inventory purposes, yield and stability problems, potential disruptions to...

  14. 21 CFR 1303.11 - Aggregate production quotas.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Aggregate production quotas. 1303.11 Section 1303.11 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE QUOTAS Aggregate Production... manufacturing and for inventory purposes, yield and stability problems, potential disruptions to...

  15. Productivity and the services of capital and labor

    SciTech Connect

    Baily, M.N.

    1981-01-01

    This paper argues that the slowdown in labor productivity growth that has occurred since 1968 and particularly since 1973 has probably been caused by a decline in the services of capital and labor relative to the measured quantities of these inputs. There is enough suggestive evidence of a decrease in effective labor input relative to measured labor hours to attribute about one-seventh of the productivity growth decline to this source. These effects have been concentrated outside the main manufacturing and industrial sectors. The most important cause of the growth slowdown in recent years seems to be a decline in the services of capital, caused by obsolescence and by the diversion of some part of capital spending to saving energy or product conversion. According to the model in this paper, conventional estimates based on the measured capital stock overstated the rate of total factor productivity growth through the mid-1960s, and the steady-state productivity growth rate of the US economy is lower than has been thought. Thus some part of the recent productivity slow-down is simply a return to the long-run steady-state path. An implication of this paper is that investment may do more to improve productivity growth than a coventional analysis predicts. There is an important qualification to this conclusion. We will gain little by adding substantially to the growth rate of gross output if we add little to output net of economic depreciation. The payoff to investment will be exceptionally large provided that new capital can avoid the problem of obsolescence that slowed productivity during the past decade. 64 references, 6 tables.

  16. 77 FR 70473 - Child Labor, Forced Labor, and Forced or Indentured Child Labor in the Production of Goods in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-26

    ... Child Labor, Forced Labor and Human Trafficking (OCFT) at the email or physical address below by 5 p.m... that ILAB follows in developing the TVPRA List (72 FR 73374). The guidelines set forth the criteria by.... List''), identified by country of origin, that the Department, in consultation and cooperation with...

  17. A deterministic aggregate production planning model considering quality of products

    NASA Astrophysics Data System (ADS)

    Madadi, Najmeh; Yew Wong, Kuan

    2013-06-01

    Aggregate Production Planning (APP) is a medium-term planning which is concerned with the lowest-cost method of production planning to meet customers' requirements and to satisfy fluctuating demand over a planning time horizon. APP problem has been studied widely since it was introduced and formulated in 1950s. However, in several conducted studies in the APP area, most of the researchers have concentrated on some common objectives such as minimization of cost, fluctuation in the number of workers, and inventory level. Specifically, maintaining quality at the desirable level as an objective while minimizing cost has not been considered in previous studies. In this study, an attempt has been made to develop a multi-objective mixed integer linear programming model that serves those companies aiming to incur the minimum level of operational cost while maintaining quality at an acceptable level. In order to obtain the solution to the multi-objective model, the Fuzzy Goal Programming approach and max-min operator of Bellman-Zadeh were applied to the model. At the final step, IBM ILOG CPLEX Optimization Studio software was used to obtain the experimental results based on the data collected from an automotive parts manufacturing company. The results show that incorporating quality in the model imposes some costs, however a trade-off should be done between the cost resulting from producing products with higher quality and the cost that the firm may incur due to customer dissatisfaction and sale losses.

  18. Ceramic ware waste as coarse aggregate for structural concrete production.

    PubMed

    García-González, Julia; Rodríguez-Robles, Desirée; Juan-Valdés, Andrés; Morán-Del Pozo, Julia M; Guerra-Romero, M Ignacio

    2015-01-01

    The manufacture of any kind of product inevitably entails the production of waste. The quantity of waste generated by the ceramic industry, a very important sector in Spain, is between 5% and 8% of the final output and it is therefore necessary to find an effective waste recovery method. The aim of the study reported in the present article was to seek a sustainable means of managing waste from the ceramic industry through the incorporation of this type of waste in the total replacement of conventional aggregate (gravel) used in structural concrete. Having verified that the recycled ceramic aggregates met all the technical requirements imposed by current Spanish legislation, established in the Code on Structural Concrete (EHE-08), then it is prepared a control concrete mix and the recycled concrete mix using 100% recycled ceramic aggregate instead of coarse natural aggregate. The concretes obtained were subjected to the appropriate tests in order to conduct a comparison of their mechanical properties. The results show that the concretes made using ceramic sanitary ware aggregate possessed the same mechanical properties as those made with conventional aggregate. It is therefore possible to conclude that the reuse of recycled ceramic aggregate to produce recycled concrete is a feasible alternative for the sustainable management of this waste. PMID:25188783

  19. Ceramic ware waste as coarse aggregate for structural concrete production.

    PubMed

    García-González, Julia; Rodríguez-Robles, Desirée; Juan-Valdés, Andrés; Morán-Del Pozo, Julia M; Guerra-Romero, M Ignacio

    2015-01-01

    The manufacture of any kind of product inevitably entails the production of waste. The quantity of waste generated by the ceramic industry, a very important sector in Spain, is between 5% and 8% of the final output and it is therefore necessary to find an effective waste recovery method. The aim of the study reported in the present article was to seek a sustainable means of managing waste from the ceramic industry through the incorporation of this type of waste in the total replacement of conventional aggregate (gravel) used in structural concrete. Having verified that the recycled ceramic aggregates met all the technical requirements imposed by current Spanish legislation, established in the Code on Structural Concrete (EHE-08), then it is prepared a control concrete mix and the recycled concrete mix using 100% recycled ceramic aggregate instead of coarse natural aggregate. The concretes obtained were subjected to the appropriate tests in order to conduct a comparison of their mechanical properties. The results show that the concretes made using ceramic sanitary ware aggregate possessed the same mechanical properties as those made with conventional aggregate. It is therefore possible to conclude that the reuse of recycled ceramic aggregate to produce recycled concrete is a feasible alternative for the sustainable management of this waste.

  20. 48 CFR 52.222-18 - Certification Regarding Knowledge of Child Labor for Listed End Products.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Knowledge of Child Labor for Listed End Products. 52.222-18 Section 52.222-18 Federal Acquisition... CONTRACT CLAUSES Text of Provisions and Clauses 52.222-18 Certification Regarding Knowledge of Child Labor... Regarding Knowledge of Child Labor for Listed End Products (FEB 2001) (a) Definition. Forced or...

  1. 48 CFR 52.222-18 - Certification Regarding Knowledge of Child Labor for Listed End Products.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Knowledge of Child Labor for Listed End Products. 52.222-18 Section 52.222-18 Federal Acquisition... CONTRACT CLAUSES Text of Provisions and Clauses 52.222-18 Certification Regarding Knowledge of Child Labor... Regarding Knowledge of Child Labor for Listed End Products (FEB 2001) (a) Definition. Forced or...

  2. 48 CFR 52.222-18 - Certification Regarding Knowledge of Child Labor for Listed End Products.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Knowledge of Child Labor for Listed End Products. 52.222-18 Section 52.222-18 Federal Acquisition... CONTRACT CLAUSES Text of Provisions and Clauses 52.222-18 Certification Regarding Knowledge of Child Labor... Regarding Knowledge of Child Labor for Listed End Products (FEB 2001) (a) Definition. Forced or...

  3. 48 CFR 52.222-18 - Certification Regarding Knowledge of Child Labor for Listed End Products.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Knowledge of Child Labor for Listed End Products. 52.222-18 Section 52.222-18 Federal Acquisition... CONTRACT CLAUSES Text of Provisions and Clauses 52.222-18 Certification Regarding Knowledge of Child Labor... Regarding Knowledge of Child Labor for Listed End Products (FEB 2001) (a) Definition. Forced or...

  4. 48 CFR 52.222-18 - Certification Regarding Knowledge of Child Labor for Listed End Products.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Knowledge of Child Labor for Listed End Products. 52.222-18 Section 52.222-18 Federal Acquisition... CONTRACT CLAUSES Text of Provisions and Clauses 52.222-18 Certification Regarding Knowledge of Child Labor... Regarding Knowledge of Child Labor for Listed End Products (FEB 2001) (a) Definition. Forced or...

  5. 19 CFR 12.45 - Transportation and marketing of prison-labor products.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Transportation and marketing of prison-labor products. 12.45 Section 12.45 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND..., Or Indentured Labor § 12.45 Transportation and marketing of prison-labor products. If any...

  6. 19 CFR 12.45 - Transportation and marketing of prison-labor products.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false Transportation and marketing of prison-labor products. 12.45 Section 12.45 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND..., Or Indentured Labor § 12.45 Transportation and marketing of prison-labor products. If any...

  7. 19 CFR 12.45 - Transportation and marketing of prison-labor products.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false Transportation and marketing of prison-labor products. 12.45 Section 12.45 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND..., Or Indentured Labor § 12.45 Transportation and marketing of prison-labor products. If any...

  8. 19 CFR 12.45 - Transportation and marketing of prison-labor products.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Transportation and marketing of prison-labor products. 12.45 Section 12.45 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND..., Or Indentured Labor § 12.45 Transportation and marketing of prison-labor products. If any...

  9. 19 CFR 12.45 - Transportation and marketing of prison-labor products.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false Transportation and marketing of prison-labor products. 12.45 Section 12.45 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND..., Or Indentured Labor § 12.45 Transportation and marketing of prison-labor products. If any...

  10. Production of manufactured aggregates from flue gas desulfurization by-products

    SciTech Connect

    Wu, M.M.; McCoy, D.C.; Fenger, M.L.; Scandrol, R.O.; Winschel, R.A.; Withum, J.A.; Statnick, R.M.

    1999-07-01

    CONSOL R and D has developed a disk pelletization process to produce manufactured aggregates from the by-products of various technologies designed to reduce sulfur emissions produced from coal utilization. Aggregates have been produced from the by-products of the Coolside and LIMB sorbent injection, the fluidized-bed combustion (FBC), spray dryer absorption (SDA), and lime and limestone wet flue gas desulfurization (FGD) processes. The aggregates produced meet the general specifications for use as road aggregate in road construction and for use as lightweight aggregate in concrete masonry units. Small field demonstrations with 1200 lb to 5000 lb of manufactured aggregates were conducted using aggregates produced from FBC ash and lime wet FGD sludge in road construction and using aggregates made from SDA ash and lime wet FGD sludge to manufacture concrete blocks. The aggregates for this work were produced with a bench-scale (200--400 lb batch) unit. In 1999, CONSOL R and D constructed and operated a 500 lb/hr integrated, continuous pilot plant. A variety of aggregate products were produced from lime wet FGD sludge. The pilot plant test successfully demonstrated the continuous, integrated operation of the process. The pilot plant demonstration was a major step toward commercialization of manufactured aggregate production from FGD by-products. In this paper, progress made in the production of aggregates from dry FGD (Coolside, LIMB, SDA) and FBC by-products, and lime wet FGD sludge is discussed. The discussion covers bench-scale and pilot plant aggregate production and aggregate field demonstrations.

  11. 75 FR 8402 - Child Labor, Forced Labor, and Forced or Indentured Child Labor in the Production of Goods in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... goods (72 FR 73374). The guidelines set forth the criteria by which information is evaluated... believe might have been mined, produced or manufactured with forced or indentured child labor (66 FR 5353... appropriate, revising the List (66 FR 5351). Based on DOL research and information submitted by the...

  12. 21 CFR 1303.13 - Adjustments of aggregate production quotas.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Adjustments of aggregate production quotas. 1303.13 Section 1303.13 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE QUOTAS... availability of raw materials for use in manufacturing and for inventory purposes, yield and stability...

  13. 21 CFR 1303.13 - Adjustments of aggregate production quotas.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Adjustments of aggregate production quotas. 1303.13 Section 1303.13 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE QUOTAS... availability of raw materials for use in manufacturing and for inventory purposes, yield and stability...

  14. Production of lightweight aggregates from washing aggregate sludge and fly ash

    NASA Astrophysics Data System (ADS)

    González-Corrochano, Beatriz; Alonso-Azcárate, Jacinto; Rodas, Magdalena

    2010-05-01

    Increasing generation of wastes is one of the main environmental problems in industrialised countries. Heat treatment at high temperatures can convert some types of wastes into ceramic products with a wide range of microstructural features and properties (Bethanis et al., 2004). A lightweight aggregate (LWA) is a granular material with a bulk density (bd) not exceeding 1.20 g/cm3 or with a particle density not exceeding 2.00 g/cm3 (UNE-EN-13055-1, 2003). They have become a focus of interest because the low particle density and the low bulk density entail a decrease in the load transmitted to the ground, and less work and effort are required to transport them (De' Gennaro et al., 2004). The benefits associated with these low densities, which are due to the formation of voids and pores, are very good thermal and acoustic insulation and materials with a good resistance to fire (Benbow, 1987; Fakhfakh et al., 2007). The objective was to recycle fly ash, used motor oil from cars and mineral wastes from washing aggregate sludge, in order to obtain a usable material such as lightweight aggregates, and also to ensure that they are of good quality for different applications. Raw materials have been physically, chemically and mineralogically characterized. On the basis of the results obtained, they were mixed, milled to a grain size of less than 200 μm (Yasuda, 1991), formed into pellets, pre-heated for 5 min and sintered in a rotary kiln at 1150°C, 1175°C, 1200°C and 1225°C for 10 and 15 min at each temperature (Theating). Effects of raw material characteristics, heating temperature and dwell time on the following LWAs properties were determined: loss on ignition (LOI), bloating index (BI), loose bulk density (bd), apparent and dry particle density (ad, dd), voids (H), water absorption (WA24h) and compressive strength (S). The products obtained were lightweight aggregates in accordance with norm UNE-EN-13055-1 (bd ≤1.20 g/cm3 or particle density ≤2.00 g/cm3). LWAs

  15. Across species-pool aggregation alters grassland productivity and diversity.

    PubMed

    McKenna, Thomas P; Yurkonis, Kathryn A

    2016-08-01

    Plant performance is determined by the balance of intra- and interspecific neighbors within an individual's zone of influence. If individuals interact over smaller scales than the scales at which communities are measured, then altering neighborhood interactions may fundamentally affect community responses. These interactions can be altered by changing the number (species richness), abundances (species evenness), and positions (species pattern) of the resident plant species, and we aimed to test whether aggregating species at planting would alter effects of species richness and evenness on biomass production at a common scale of observation in grasslands. We varied plant species richness (2, 4, or 8 species and monocultures), evenness (0.64, 0.8, or 1.0), and pattern (planted randomly or aggregated in groups of four individuals) within 1 × 1 m plots established with transplants from a pool of 16 tallgrass prairie species and assessed plot-scale biomass production and diversity over the first three growing seasons. As expected, more species-rich plots produced more biomass by the end of the third growing season, an effect associated with a shift from selection to complementarity effects over time. Aggregating conspecifics at a 0.25-m scale marginally reduced biomass production across all treatments and increased diversity in the most even plots, but did not alter biodiversity effects or richness-productivity relationships. Results support the hypothesis that fine-scale species aggregation affects diversity by promoting species coexistence in this system. However, results indicate that inherent changes in species neighborhood relationships along grassland diversity gradients may only minimally affect community (meter) - scale responses among similarly designed biodiversity-ecosystem function studies. Given that species varied in their responses to local aggregation, it may be possible to use such species-specific results to spatially design larger-scale grassland

  16. PRODUCTION OF CONSTRUCTION AGGREGATES FROM FLUE GAS DESULFURIZATION SLUDGE

    SciTech Connect

    M.M. Wu; D.C. McCoy; R.O. Scandrol; M.L. Fenger; J.A. Withum; R.M. Statnick

    2000-05-01

    The three main conclusions of this report are: (1) The pilot plant successfully demonstrated the continuous, fully-integrated, long-term process operation, including the mixing, pelletizing, and curing steps for aggregate production. The curing vessel, which was designed for the pilot plant test, was operated in a mass flow mode and performed well during pilot plant operation. (2) The pilot plant test demonstrated process flexibility. The same equipment was used to produce lightweight, medium-weight, and road aggregates. The only change was the mix formulation. Aggregates were produced from a variety of mix designs and from FGD sludge with solids concentrations between 45.0% and 56.7% and moisture contents between 55.0% and 43.3%. (3) The pilot plant provided operating data and experience to design and cost a commercial plant, which was not part of the cooperative agreement.

  17. 9 CFR 381.203 - Products offered for entry; charges for storage, cartage, and labor with respect to products...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... for storage, cartage, and labor with respect to products which are refused entry. 381.203 Section 381.203 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY... entry; charges for storage, cartage, and labor with respect to products which are refused entry....

  18. 78 FR 48193 - Final Adjusted Aggregate Production Quotas for Schedule I and II Controlled Substances and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-07

    ... Enforcement Administration Final Adjusted Aggregate Production Quotas for Schedule I and II Controlled.... SUMMARY: This notice establishes final adjusted 2013 aggregate production quotas for controlled substances... List I chemicals ephedrine, pseudoephedrine, and phenylpropanolamine, as well as the 2013...

  19. Lightweight aggregate production from claystone and shale in Bangladesh

    USGS Publications Warehouse

    Parker, Norbert A.; Khan, M.A.

    1976-01-01

    Muffle furnace tests were made on samples of clay, claystone, and shale collected in the Chittagong and Dacca areas of East Pakistan to determine their amenability to bloating for the commercial production of light-weight aggregate. Several areas, sampled in some detail, were selected for investigation because of their proximity to market, and accessibility to fuel and electricity. Muffle furnace tests show that the clay, claystone, and shale are natural bloaters at temperatures in the 1700? to 2200? F range, and do not require additives. The most desirable deposit, insofar as producing a strong aggregate is concerned, can be determined only by pilot-kiln testing and by crushing-strength tests made on concrete test cylinders. Reserves of suitable raw material are large in both the Chittagong and Dacca areas.

  20. Production of aggregate from non-metallic automotive shredder residues.

    PubMed

    Rossetti, Vito Alunno; Di Palma, Luca; Medici, Franco

    2006-09-21

    In this paper, the results of an experimentation on the production of granules suitable to be used as aggregates in cementitious or asphalt mixes are presented and discussed. The granules were obtained by granulating the non-metallic fraction of automotive shredder residues. In a preliminary separation step the fluff fraction containing mainly inert and non-metallic materials was sieved and analyzed for the metal content. In the following granulation step, the sieved fraction was mixed with binding materials, fly ash and a densifier agent, to produce granules of 5-30 mm of diameter and up to 1400 kg/m3 of specific weight. The granulation was carried out at room temperature in a rotating tank. Concrete samples prepared using as aggregates the produced granules showed a specific weight up to 1800 kg/m3 and a compressive strength up to about 55% of reference samples prepared using a calcareous aggregate, depending on the fluff content of the mixes, and on the nature of the binder and of the other components used.

  1. Productivity --- 8 for 8. [Labor Relations at Gulf Oil

    SciTech Connect

    Breaux, M.P.

    1983-03-01

    According to the author, a spokesman for Gulf Oil Corporation, the petroleum industry in the United States has reason to be proud of its record in labor relations, in labor negotiations, and in the success of its bargaining. For many years, this industry found itself alone in advocating noncompliance with COLAs and not participating in fully paid medical plans and other labor programs other industries felt it necessary to adopt and underwrite. This staunch resistance lent the petroleum industry, over the years, the reputation of an industrial dinosaur, but this has lately changed as industry at large, especially during an economic recession, has seen the wisdom behind the motives of the petroleum industry. The author goes on to state that Gulf's employees are well paid and that the last contract, stipulating a 9 percent and 7 percent increase over the next two years, was a bilaterally fair settlement.

  2. [Productive restructuring and its impact on labor relations in the public health services in Brazil].

    PubMed

    Martins, Maria Inês Carsalade; Molinaro, Alex

    2013-06-01

    The restructuring of productive systems and economic globalization are directly impacting the basic social rights of workers. In the semi-peripheral countries such as Brazil, where the wage-based society and the consolidation of social rights are not completely implemented, this process of change in the world of labor contributes to aggravate the inequality in the capital-labor relationship and hampers access to employment. By means of a critical review of the scientific literature regarding changes in the world of labor and its impact on the organization and production of health services in Brazil, this article pinpoints the weakness of regulation of the labor market in Brazil, especially in the health sector. It also stresses the need to increase the debate on new forms of institutionalization of the labor relationship in order to ensure equity in the workplace and protect the rights to work and in the workplace.

  3. DURABILITY EVALUATION AND PRODUCTION OF MANUFACTURED AGGREGATES FROM COAL COMBUSTION BY-PRODUCTS

    SciTech Connect

    M. M. Wu

    2005-02-01

    Under the cooperative agreement with DOE, the Research and Development Department of CONSOL Energy (CONSOL R&D), teamed with Universal Aggregates, LLC, to conduct a systematic study of the durability of aggregates manufactured using a variety of flue gas desulfurization (FGD), fluidized-bed combustion (FBC) and fly ash specimens with different chemical and physical properties and under different freeze/thaw, wet/dry and long-term natural weathering conditions. The objectives of the study are to establish the relationships among the durability and characteristics of FGD material, FBC ash and fly ash, and to identify the causes of durability problems, and, ultimately, to increase the utilization of FGD material, FBC ash and fly ash as a construction material. Manufactured aggregates made from FGD material, FBC ash and fly ash, and products made from those manufactured aggregates were used in the study. The project is divided into the following activities: sample collection and characterization; characterization and preparation of manufactured aggregates; determination of durability characteristics of manufactured aggregates; preparation and determination of durability characteristics of manufactured aggregate products; and data evaluation and reporting.

  4. Mine-to-Mill Optimization of Aggregate Production

    SciTech Connect

    Greg Adel; Toni Kojovic; Darren Thornton

    2006-09-30

    Mine-to-Mill optimization is a total systems approach to the reduction of energy and cost in mining and processing. Developed at the Julius Krutschnitt Mineral Research Center in Queensland, Australia, the Mine-to-Mill approach attempts to minimize energy consumption through optimization of all steps in the size reduction process. The approach involves sampling and modeling of blasting and processing, followed by computer simulation to optimize the operation and develop alternatives. The most promising alternatives are implemented, and sampling is conducted to quantify benefits. In the current project, the primary objective was to adapt Mine-to-Mill technology to the aggregates industry. The first phase of this work was carried out at the Bealeton Quarry near Fredericksburg, Virginia. The second phase was carried out at the Pittsboro Quarry south of Chapel Hill, North Carolina. Both quarries are operated by Luck Stone Corporation of Richmond, Virginia. As a result of the work, several conclusions can be drawn from the project which should assist DOE in assessing the applicability of the Mine-to-Mill approach to the aggregates industry. 1. Implementation of MTM guidelines at Pittsboro has resulted in tangible improvements in productivity. It is clear that MTM guidelines represent an energy savings of around 5% (primary and secondary) and an overall energy savings of 1%. This 1-5% energy savings is also consistent with simulated results for Bealeton had side-by-side shots used to evaluate the technology been carried out in the same rockmass. 2. Luck Stone clearly runs their operations at a high standard. Hence the percentage improvement realized in this project may represent the lower end of what might be expected overall in the aggregates industry. 3. Variability in ore types across both Bealeton and Pittsboro suggests a 2:1 difference in hardness which contradicts the misconception that quarry rock is homogenous. Therefore, the idea of comparing side-by-side blasts

  5. 9 CFR 381.203 - Products offered for entry; charges for storage, cartage, and labor with respect to products...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... for storage, cartage, and labor with respect to products which are refused entry. 381.203 Section 381.203 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY... CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Imported Poultry Products § 381.203 Products offered...

  6. International Comparison of Labor Productivity Distribution for Manufacturing and Non-Manufacturing Firms

    NASA Astrophysics Data System (ADS)

    Ikeda, Y.; Souma, W.

    Labor productivity was studied at the microscopic level in terms of distributions based on individual firm financial data from Japan and the US. A power-law distribution in terms of firms and sector productivity was found in both countries' data. The labor productivities were not equal for nation and sectors, in contrast to the prevailing view in the field of economics. It was found that the low productivity of the Japanese non-manufacturing sector reported in macro-economic studies was due to the low productivity of small firms.

  7. Analysis of labor productivity using large-scale data of firm's financial statements

    NASA Astrophysics Data System (ADS)

    Ikeda, Y.; Souma, W.; Aoyama, H.; Fujiwara, Y.; Iyetomi, H.

    2010-08-01

    We investigated labor productivity distribution by analyzing large-scale financial statement data consisting of listed and unlisted Japanese firms to clarify the characteristics of the Japanese labor market. Both high and low productivity sides of the labor productivity distribution follows the power-law distribution. Large inequality in the low productivity side was observed only for the manufacturing sectors in Japan fiscal year (JFY) 1999 and observed for both the manufacturing and non-manufacturing sectors in JFY 2002. The decline in the Japanese GDP in JFY 1999 and JFY 2002 were coincided with the large inequality in the low productivity side of the distribution. A lower peak was found for all non-manufacturing sectors. This might be the origin of the low productivity of the non-manufacturing sectors reported in recent economic studies.

  8. Notes on the Incorporation of Third World Women into Wage-Labor Through Immigration and Off-Shore Production.

    ERIC Educational Resources Information Center

    Sassen-Koob, Saskia

    1984-01-01

    Immigration and off-shore production have evolved into mechanisms for the massive incorporation of Third World women into wage-labor. There is a systemic relation between this globalization and feminization of wage labor. (KH)

  9. Production of mineral aggregates in quartz tumbling experiments

    NASA Astrophysics Data System (ADS)

    Nørnberg, Per; Finster, Kai; Pall Gunnlaugsson, Haraldur; Knak Jensen, Svend; Merrison, Jonathan Peter

    2013-04-01

    Introduction Tumbling experiments with quartz sand with the purpose of tracing the effect of broken bonds in mineral surfaces resulted in an unexpected production of aggregates. These aggregates are a few microns in diameter, spherical and resembling tiny white "snowballs." Particle comminution by aeolian and other natural weathering processes are known in soil science and is often seen as an increase of fine particles towards the top of soil profiles (Nørnberg, P. 1987, 1988, 2002, J.S. Wright 2007). When mineral grains collide in aeolian processes they break up along weakness zones in the crystal lattice. This mechanism causes broken bonds between atoms in the crystal lattice and results in reactive groups in the mineral surface. This mechanism provides the background for experiments to investigate the oxidation processes of magnetite on the planet Mars. The primary magnetic iron oxide phase on Mars is to day known to be magnetite and the colour of the dust on Mars is most likely due to hematite. To investigate if the oxidation process could take place without going over dissolution and precipitation in water, experiments with tumbling of quartz grains in sealed glass containers along with magnetite were started. The idea was that activated bonds at the surface of quartz could oxidize magnetite and convert it to hematite over time. This proved to be the case (Merrison, J.P. et al. 2010). However, in these experiments we observed the formation of the white aggregates which has been the subject of the study that we present here. Results of tumbling experiments Commercially available quarts (Merck) was sieved to obtain the fraction between 125 and 1000 µm. This fraction was tumbled in glass containers for months and resulted in production of a significant amount of fine grained material (Merrison, J.P et al. 2010). A part of this fine fraction consists of the "snowball"-like aggregates which is a fragile element with relatively high specific surface. The physical

  10. Diatom aggregation and dimethylsulfide production in phytoplankton blooms

    SciTech Connect

    Crocker, K.M.

    1994-01-01

    Phytoplankton blooms are crucial links in many of the earth's biogeochemical cycles. Blooms take up atmospheric carbon through photosynthesis, and sequester it on the ocean floor by sinking. Aggregation of single cells into [open quote]marine snow[close quote] particles speeds up the sinking of algal cells. Laboratory studies investigating the process of aggregation show that some species have a higher probability of aggregating than others, and that there exist several mechanisms for causing aggregation. Field studies confirm that some species are more likely to be found in aggregates than in the surrounding seawater. High latitude Premnesiophyte blooms are found to produce large amounts of dimethylsulflde (DMS), believed to be an important chemical in global thermoregulation. DMS is found to vary diurnally, possibly due to photooxidation by ultraviolet light. This possibility links the effects of DMS on cloud formation with the effects of increased ultraviolet light penetrating the earths ozone layer.

  11. Just-in-Space: Certified Rural Products, Labor of Quality, and Regulatory Spaces

    ERIC Educational Resources Information Center

    Mutersbaugh, Tad

    2005-01-01

    Since the mid-1990s, the number and diversity of "quality-certified" products has increased dramatically. This article examines labor practices and regulatory spaces within 3rd party quality certification and suggests that this distinct configuration be termed "just-in-space" production. A privileging of space derives, on the one hand, from the…

  12. Strikes, Scabs, and Tread Separations: Labor Strife and the Production of Defective Bridgestone/firestone Tires.

    ERIC Educational Resources Information Center

    Krueger, Alan B.; Mas, Alexandre

    2004-01-01

    This paper provides a case study of the effect of labor relations on product quality. We consider whether a long, contentious strike and the hiring of replacement workers at Bridgestone/Firestone's Decatur, Illinois, plant in the mid-1990s contributed to the production of defective tires. Using several independent data sources and looking before…

  13. 48 CFR 809.270 - Qualified products for convenience/labor-saving foods.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Qualified products for convenience/labor-saving foods. 809.270 Section 809.270 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS COMPETITION AND ACQUISITION PLANNING CONTRACTOR QUALIFICATIONS Qualifications Requirements 809.270 Qualified products...

  14. 78 FR 37237 - Proposed Adjustments to the Aggregate Production Quotas for Schedule I and II Controlled...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ... Enforcement Administration Proposed Adjustments to the Aggregate Production Quotas for Schedule I and II... request for comments. SUMMARY: This notice proposes to adjust the 2013 aggregate production quotas for... of annual needs for the list I chemicals ephedrine, pseudoephedrine, and phenylpropanolamine, as...

  15. Production of lightweight aggregate from industrial waste and carbon dioxide.

    PubMed

    Gunning, Peter J; Hills, Colin D; Carey, Paula J

    2009-10-01

    The concomitant recycling of waste and carbon dioxide emissions is the subject of developing technology designed to close the industrial process loop and facilitate the bulk-re-use of waste in, for example, construction. The present work discusses a treatment step that employs accelerated carbonation to convert gaseous carbon dioxide into solid calcium carbonate through a reaction with industrial thermal residues. Treatment by accelerated carbonation enabled a synthetic aggregate to be made from thermal residues and waste quarry fines. The aggregates produced had a bulk density below 1000 kg/m(3) and a high water absorption capacity. Aggregate crushing strengths were between 30% and 90% stronger than the proprietary lightweight expanded clay aggregate available in the UK. Cast concrete blocks containing the carbonated aggregate achieve compressive strengths of 24 MPa, making them suitable for use with concrete exposed to non-aggressive service environments. The energy intensive firing and sintering processes traditionally required to produce lightweight aggregates can now be augmented by a cold-bonding, low energy method that contributes to the reduction of green house gases to the atmosphere. PMID:19577916

  16. Soil Aggregate Stability and Grassland Productivity Associations in a Northern Mixed-Grass Prairie

    PubMed Central

    Reinhart, Kurt O.; Vermeire, Lance T.

    2016-01-01

    Soil aggregate stability data are often predicted to be positively associated with measures of plant productivity, rangeland health, and ecosystem functioning. Here we revisit the hypothesis that soil aggregate stability is positively associated with plant productivity. We measured local (plot-to-plot) variation in grassland community composition, plant (aboveground) biomass, root biomass, % water-stable soil aggregates, and topography. After accounting for spatial autocorrelation, we observed a negative association between % water-stable soil aggregates (0.25–1 and 1–2 mm size classes of macroaggregates) and dominant graminoid biomass, and negative associations between the % water-stable aggregates and the root biomass of a dominant sedge (Carex filifolia). However, variation in total root biomass (0–10 or 0–30 cm depths) was either negatively or not appreciably associated with soil aggregate stabilities. Overall, regression slope coefficients were consistently negative thereby indicating the general absence of a positive association between measures of plant productivity and soil aggregate stability for the study area. The predicted positive association between factors was likely confounded by variation in plant species composition. Specifically, sampling spanned a local gradient in plant community composition which was likely driven by niche partitioning along a subtle gradient in elevation. Our results suggest an apparent trade-off between some measures of plant biomass production and soil aggregate stability, both known to affect the land’s capacity to resist erosion. These findings further highlight the uncertainty of plant biomass-soil stability associations. PMID:27467598

  17. Soil Aggregate Stability and Grassland Productivity Associations in a Northern Mixed-Grass Prairie.

    PubMed

    Reinhart, Kurt O; Vermeire, Lance T

    2016-01-01

    Soil aggregate stability data are often predicted to be positively associated with measures of plant productivity, rangeland health, and ecosystem functioning. Here we revisit the hypothesis that soil aggregate stability is positively associated with plant productivity. We measured local (plot-to-plot) variation in grassland community composition, plant (aboveground) biomass, root biomass, % water-stable soil aggregates, and topography. After accounting for spatial autocorrelation, we observed a negative association between % water-stable soil aggregates (0.25-1 and 1-2 mm size classes of macroaggregates) and dominant graminoid biomass, and negative associations between the % water-stable aggregates and the root biomass of a dominant sedge (Carex filifolia). However, variation in total root biomass (0-10 or 0-30 cm depths) was either negatively or not appreciably associated with soil aggregate stabilities. Overall, regression slope coefficients were consistently negative thereby indicating the general absence of a positive association between measures of plant productivity and soil aggregate stability for the study area. The predicted positive association between factors was likely confounded by variation in plant species composition. Specifically, sampling spanned a local gradient in plant community composition which was likely driven by niche partitioning along a subtle gradient in elevation. Our results suggest an apparent trade-off between some measures of plant biomass production and soil aggregate stability, both known to affect the land's capacity to resist erosion. These findings further highlight the uncertainty of plant biomass-soil stability associations. PMID:27467598

  18. New Mexico aggregate production sites, 1997-1999

    USGS Publications Warehouse

    Orris, Greta J.

    2000-01-01

    This report presents data, including latitude and longitude, for aggregate sites in New Mexico that were believed to be active in the period 1997-1999. The data are presented in paper form in Part A of this report and as Microsoft Excel 97 and Data Interchange Format (DIF) files in Part B. The work was undertaken as part of the effort to update information for the National Atlas. This compilation includes data from: the files of U.S. Geological Survey (USGS); company contacts; the New Mexico Bureau of Mines and Mineral Resources, New Mexico Bureau of Mine Inspection, and the Mining and Minerals Division of the New Mexico Energy, Minerals and Natural Resources Department (Hatton and others, 1998); the Bureau of Land Management Information; and direct communications with some of the aggregate operators. Additional information on most of the sites is available in Hatton and others (1998).

  19. PRODUCTION OF CONSTRUCTION AGGREGATES FROM FLUE GAS DESULFURIZATION SLUDGE

    SciTech Connect

    1998-12-01

    Through a cooperative agreement with DOE, the Research and Development Department of CONSOL Inc. (CONSOL R and D) is teaming with SynAggs, Inc. and Duquesne Light to design, construct, and operate a 500 lb/h continuous pilot plant to produce road construction aggregate from a mixture of wet flue gas desulfurization (FGD) sludge, fly ash, and other components. The proposed project is divided into six tasks: (1) Project Management; (2) Mix Design Evaluation; (3) Process Design; (4) Construction; (5) Start-Up and Operation; and (6) Reporting. In this quarter, Tasks 1 and 2 were completed. A project management plan (Task 1) was issued to DOE on October 22, 1998 . The mix design evaluation (Task 2) with Duquesne Light Elrama Station FGD sludge and Allegheny Power Hatfields Ferry Station fly ash was completed. Eight semi-continuous bench-scale tests were conducted to examine the effects of mix formulation on aggregate properties. A suitable mix formulation was identified to produce aggregates that meet specifications of the American Association of State High Transport Officials (AASHTO) as Class A aggregate for use in highway construction. The mix formulation was used in designing the flow sheet of the pilot plant. The process design (Task 3) is approximately 80% completed. Equipment was evaluated to comply with design requirements. The design for the curing vessel was completed by an outside engineering firm. All major equipment items for the pilot plant, except the curing vessel, were ordered. Pilot plant construction (Task 4) was begun in October. The Hazardous Substance Plan was issued to DOE. The Allegheny County (PA) Heat Department determined that an air emission permit is not required for operation of the pilot plant.

  20. Trends in hospital labor and total factor productivity, 1981-86

    PubMed Central

    Cromwell, Jerry; Pope, Gregory C.

    1989-01-01

    The per-case payment rates of Medicare's prospective payment system are annually updated. As one element of the update factor, Congress required consideration of changes in hospital productivity. In this article, calculations of annual changes in labor and total factor productivity during 1981-86 of hospitals eligible for prospective payment are presented using several output and input variants. Generally, productivity has declined since 1980, although the rates of decline have slowed since prospective payment implementation. According to the series of analyses most relevant for policy, significant hospital productivity gains occurred during 1983-86. This may justify a lower update factor. PMID:10313278

  1. Productivity or discrimination? An economic analysis of excess-weight penalty in the Swedish labor market.

    PubMed

    Dackehag, Margareta; Gerdtham, Ulf-G; Nordin, Martin

    2015-07-01

    This article investigates the excess-weight penalty in income for men and women in the Swedish labor market, using longitudinal data. It compares two identification strategies, OLS and individual fixed effects, and distinguishes between two main sources of excess-weight penalties, lower productivity because of bad health and discrimination. For men, the analysis finds a significant obesity penalty related to discrimination when applying individual fixed effects. We do not find any significant excess-weight penalty for women. PMID:24903023

  2. Valorization of lignite combustion residues and ferroalumina in the production of aggregates.

    PubMed

    Anagnostopoulos, I M; Stivanakis, V E; Angelopoulos, G N; Papamantellos, D C

    2010-02-15

    The present research study investigates the synergy of industrial solid by-products from lignite combustion (fly ash and bottom ash) and aluminum production (ferroalumina) in the production of lightweight aggregates (LWA). The process consists of two stages, pelletization and sintering. Bottom ash (BA) is used as the principal raw material in mixtures while ferroalumina (FAL) is added in lower percentages (5-30 wt%). BA carbon content is used as the fuel of sintering process in high temperatures, around 1250 degrees C, and gas generation is responsible for porous structure formation. Physical properties such as porosity, water absorption and bulk density, of sintering products are measured. Increase of FAL percentage in sintering mixtures results in decrease of porosity from 61% to 35% and of water absorption from 61% to 21% and in increase of bulk density from 1.02 g/cm(3) to 1.80 g/cm(3) of the produced aggregates. Aggregates produced by FAL addition up to 20 wt% are characterized as LWA. Aggregates formed are used in the production of concrete specimens. Compressive strength of concrete increases by increasing FAL addition in aggregates from 5 wt% to 15 wt% (highest strength value), while decrease by increasing FAL addition from 20 wt% to 30 wt%. FAL addition in lignite ashes sintering mixtures (up to 15 wt%) is considered as an important parameter for enhancing aggregates strength. PMID:19850411

  3. Comparison of antibody molecules produced from two cell lines with contrasting productivities and aggregate contents.

    PubMed

    Ishii, Yoichi; Imamoto, Yasufumi; Yamamoto, Rie; Tsukahara, Masayoshi; Wakamatsu, Kaori

    2015-01-01

    Cell culture processes that produce therapeutic antibodies with high productivity (titer) and low aggregate content reduce the risk of adverse effects and expense to patients. To elucidate the mechanism of aggregate formation, we compared trastuzumab samples produced from two contrasting cell lines: cell line A, which exhibits high titer and low aggregate content, and cell line B, which exhibits low titer and high aggregate content. Cell line B produced significantly fewer (approximately 1/3) antibodies compared with cell line A and contained higher (approximately 3-fold) percentages of aggregates. The aggregates of antibodies found in the protein A-purified samples of cell line B were associated mostly with noncovalent interactions. Cell line B exhibited a low content of monomers/dimers of light chains in the medium and within cells. Because light chains are essential for the correct folding of heavy chains and secretion of mature antibodies, the characteristics of cell line B may be attributed to low levels of light chain production. In addition, protein A-purified antibodies from cell line B (but not those from cell line A) contained fragments that are expected to expose the hydrophobic CH3 domain, which may serve as nuclei for aggregation. PMID:25501618

  4. Method for the production of cementitious compositions and aggregate derivatives from said compositions

    DOEpatents

    Minnick, L. John

    1981-01-01

    Method for the production of cementitious compositions and aggregate derivatives of said compositions, and cementitious compositions and aggregates produced by said method, wherein fluidized bed combustion residue and pozzolanic material, such as pulverized coal combustion system fly ash, are incorporated in a cementitious mix. The mix is cast into desired shape and cured. If desired, the shape may then be crushed so as to result in a fluidized bed combustion residue-fly ash aggregate material or the shape may be used by itself.

  5. A new multi-period linguistic aggregation operator and its application to financial product selection

    NASA Astrophysics Data System (ADS)

    Liu, Xiaoli; Yang, Wei

    2013-03-01

    In this paper, we propose a new aggregation operator, dynamic 2-tuple linguistic weighted averaging (DTWA) operator, to aggregate linguistic information given in multiple periods. The properties of the new operator are studied and a new multiple attribute decision making method based on the new operator is proposed. Finally, financial product selection problem is provided to illustrate the the proposed method in financial decision making problem.

  6. Silicification-induced cell aggregation for the sustainable production of H2 under aerobic conditions.

    PubMed

    Xiong, Wei; Zhao, Xiaohong; Zhu, Genxing; Shao, Changyu; Li, Yaling; Ma, Weimin; Xu, Xurong; Tang, Ruikang

    2015-10-01

    Photobiological hydrogen production is of great importance because of its promise for generating clean renewable energy. In nature, green algae cannot produce hydrogen as a result of the extreme sensitivity of hydrogenase to oxygen. However, we find that silicification-induced green algae aggregates can achieve sustainable photobiological hydrogen production even under natural aerobic conditions. The core-shell structure of the green algae aggregates creates a balance between photosynthetic electron generation and hydrogenase activity, thus allowing the production of hydrogen. This finding provides a viable pathway for the solar-driven splitting of water into hydrogen and oxygen to develop green energy alternatives by using rationally designed cell-material complexes.

  7. Mine-to-Mill Optimization of Aggregate Production

    SciTech Connect

    Greg Adel; Toni Kojovic; Darren Thornton

    2006-06-01

    Mine-to-Mill optimization is a total systems approach to the reduction of energy and cost in mining and mineral processing operations. Developed at the Julius Krutschnitt Mineral Research Centre (JKMRC) in Queensland, Australia, the Mine-to-Mill approach attempts to minimize energy consumption through the optimization of all steps in the size reduction process. The approach involves sampling and modeling of blasting and processing, followed by computer simulation to optimize the operation and develop alternatives. The most promising alternatives are implemented, and sampling is conducted to quantify energy savings. In the current project, the primary objective is to adapt the JKMRC Mine-to-Mill technology to the aggregates industry. The second phase of this project is being carried out at the Pittsboro Quarry located south of Chapel Hill, North Carolina. This quarry is owned by 3M Corporation and operated by Luck Stone. Based on lessons learned from the first phase work, long-term monitoring ({approx} three months) of all quarry operations is being carried out to minimize the impact of geological changes during the mining process. To date, the blasting and processing operations have been audited and modeled, the long-term monitoring of current Luck Stone practice has been completed, and a modified blasting approach has been implemented based on the results of simulations using JKSimBlast and JKSimPlant. The modified blasting approach is expected to increase the primary throughput by 15% and the secondary throughput by approximately 6%, with an overall specific energy reduction of around 1%. Long-term monitoring is currently underway to evaluate the impact the modified blasting approach. This report summarizes the current status of work at the Pittsboro Quarry.

  8. Effect of cocoa products and flavanols on platelet aggregation in humans: a systematic review.

    PubMed

    Peluso, Ilaria; Palmery, Maura; Serafini, Mauro

    2015-07-01

    Previous evidence suggested an active role of cocoa products and flavanols in modulating platelet aggregation. However, cocoa flavanols are characterized by a low bioavailability that can deeply affect their presence in biological fluids and raise questions on their biological effect in humans. We performed a systematic search on Medline, Embase, Cochrane and ProQuest databases, until April 2015, on the effect of cocoa products on platelet aggregation in human intervention studies. We identified 13 interventions, of which only five involved repeated administration. Different effects were observed on the basis of the platelet aggregation test used, whereas neither a longer duration of treatment nor a higher dose was associated with a higher inhibition of platelet aggregation. In conclusion, the reviewed results suggest that consumption of cocoa products in bolus administration positively affects platelet aggregation in both healthy subjects and diseased patients. On the other hand, more evidence is required in order to assess the effect of long-term cocoa product ingestion and to identify the bioactive components involved.

  9. A novel heuristic for optimization aggregate production problem: Evidence from flat panel display in Malaysia

    NASA Astrophysics Data System (ADS)

    Al-Kuhali, K.; Hussain M., I.; Zain Z., M.; Mullenix, P.

    2015-05-01

    Aim: This paper contribute to the flat panel display industry it terms of aggregate production planning. Methodology: For the minimization cost of total production of LCD manufacturing, a linear programming was applied. The decision variables are general production costs, additional cost incurred for overtime production, additional cost incurred for subcontracting, inventory carrying cost, backorder costs and adjustments for changes incurred within labour levels. Model has been developed considering a manufacturer having several product types, which the maximum types are N, along a total time period of T. Results: Industrial case study based on Malaysia is presented to test and to validate the developed linear programming model for aggregate production planning. Conclusion: The model development is fit under stable environment conditions. Overall it can be recommended to adapt the proven linear programming model to production planning of Malaysian flat panel display industry.

  10. COIN Project: Towards a zero-waste technology for concrete aggregate production in Norway

    NASA Astrophysics Data System (ADS)

    Cepuritis, Rolands; Willy Danielsen, Svein

    2014-05-01

    COIN Project: Towards a zero-waste technology for concrete aggregate production in Norway Rolands Cepuritis, Norcem/NTNU and Svein Willy Danielsen, SINTEF Aggregate production is a mining operation where no purification of the "ore" is necessary. Still it is extremely rare that an aggregate production plant is operating on the basis of zero-waste concept. This is since historically the fine crushed aggregate (particles with a size of less than 2, 4 or sometimes 8 mm) has been regarded as a by-product or waste of the more valuable coarse aggregate production. The reason is that the crushed coarse aggregates can easily replace coarse rounded natural stones in almost any concrete composition; while, the situation with the sand is different. The production of coarse aggregate normally yields fine fractions with rough surface texture, flaky or elongated particles an inadequate gradation. When such a material replaces smooth and rounded natural sand grains in a concrete mix, the result is usually poor and much more water and cement has to be used to achieve adequate concrete flow. The consequences are huge stockpiles of the crushed fine fractions that can't be sold (mass balance problems) for the aggregate producers, sustainability problems for the whole industry and environmental issues for society due to dumping and storing of the fine co-generated material. There have been attempts of utilising the material in concrete before; however, they have mostly ended up in failure. There have been attempts to adjust the crushed sand to the properties of the natural sand, which would still give a lot of waste, especially if the grading would have to be adjusted and the high amounts of fines abundantly present in the crushed sand would have to be removed. Another fundamental reason for failure has been that historically such attempts have mainly ended up in a research carried out by people (both industrial and academic) with aggregate background (= parties willing to find market

  11. Construction aggregates

    USGS Publications Warehouse

    Tepordei, V.V.

    1995-01-01

    Part of the 1994 Industrial Minerals Review. The production, consumption, and applications of construction aggregates are reviewed. In 1994, the production of construction aggregates, which includes crushed stone and construction sand and gravel combined, increased 7.7 percent to 2.14 Gt compared with the previous year. These record production levels are mostly a result of funding for highway construction work provided by the Intermodal Surface Transportation Efficiency Act of 1991. Demand is expected to increase for construction aggregates in 1995.

  12. Inhibition of IAPP Aggregation and Toxicity by Natural Products and Derivatives

    PubMed Central

    Pithadia, Amit; Brender, Jeffrey R.; Fierke, Carol A.; Ramamoorthy, Ayyalusamy

    2016-01-01

    Fibrillar aggregates of human islet amyloid polypeptide, hIAPP, a pathological feature seen in some diabetes patients, are a likely causative agent for pancreatic beta-cell toxicity, leading to a transition from a state of insulin resistance to type II diabetes through the loss of insulin producing beta-cells by hIAPP induced toxicity. Because of the probable link between hIAPP and the development of type II diabetes, there has been strong interest in developing reagents to study the aggregation of hIAPP and possible therapeutics to block its toxic effects. Natural products are a class of compounds with interesting pharmacological properties against amyloids which have made them interesting targets to study hIAPP. Specifically, the ability of polyphenolic natural products, EGCG, curcumin, and resveratrol, to modulate the aggregation of hIAPP is discussed. Furthermore, we have outlined possible mechanistic discoveries of the interaction of these small molecules with the peptide and how they may mitigate toxicity associated with peptide aggregation. These abundantly found agents have been long used to combat diseases for many years and may serve as useful templates toward developing therapeutics against hIAPP aggregation and toxicity. PMID:26649317

  13. 77 FR 55500 - Controlled Substances: Final Adjusted Aggregate Production Quotas for 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-10

    ... substances in Schedules I and II (76 FR 78044). That notice stated that the Administrator would adjust, as..., 2012 (77 FR 39737) in consideration of the outlined criteria. All interested persons were invited to... aggregate production quotas for these substances as published on July 5, 2012, at 77 FR 39737 are...

  14. 76 FR 77016 - Controlled Substances: Final Adjusted Aggregate Production Quotas for 2011

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-09

    ... aggregate production quotas for controlled substances in Schedules I and II (75 FR 79404). That notice... subsequently published in the Federal Register on September 14, 2011, (76 FR 56810) in consideration of the... substances. On March 1, 2011, the DEA Administrator published a final order (76 FR 11075) which...

  15. 75 FR 35838 - Controlled Substances: Proposed Revised Aggregate Production Quotas for 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-23

    ... for certain controlled substances in schedules I and II was published in the Federal Register (74 FR... FR 54080) on October 21, 2010. The proposed revised 2010 aggregate production quotas represent those... Ibogaine 1 g 1 g Lysergic acid diethylamide (LSD) 15 g 15 g Marihuana 4,500,000 g 11,000 g Mescaline 7 g...

  16. 76 FR 78044 - Controlled Substances: Established Aggregate Production Quotas for 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-15

    ... Federal Register (76 FR 65537). That notice proposed the 2012 aggregate production quotas for each basic... pursuant to the final order also published on October 21, 2011, at 76 FR 65371. No comments were received... Ibogaine 5 g Lysergic acid diethylamide (LSD) 16 g Marihuana 21,000 g Mescaline 5 g Methaqualone 10...

  17. Antiretroviral therapy, labor productivity, and gender: a longitudinal cohort study of tea pluckers in Kenya

    PubMed Central

    LARSON, Bruce. A.; FOX, Matthew P.; BII, Margaret; ROSEN, Sydney; ROHR, Julia; SHAFFER, Douglas; SAWE, Fredrick; WASUNNA, Monique; SIMON, Jonathon L.

    2014-01-01

    Objective To estimate the impact of antiretroviral therapy (ART) on labor productivity and income using detailed employment data from two large tea plantations in western Kenya for HIV-infected tea pluckers who initiated ART. Design Longitudinal study using primary data on key employment outcomes for a group of HIV-infected workers receiving anti-retroviral therapy (ART) and workers in the general workforce. Methods We used nearest-neighbor matching methods to estimate the impacts of HIV/AIDS and ART among 237 HIV-positive pluckers on ART (index group) over a four year period (2 years pre- and post-ART) on four monthly employment outcomes—days plucking tea, total kilograms harvested, total days working, and total labor income. Outcomes for the index group were compared to those for a matched reference group from the general workforce. Results We observed a rapid deterioration in all four outcomes for HIV-infected subjects in the period before ART initiation and then a rapid improvement after treatment initiation. By 18–24 months after treatment initiation, the index group harvested 8% (males) and 19% (females) less tea than reference subjects. The index group earned 6% (males) and 9% (females) less income from labor than reference subjects. Women’s income would have dropped further if they had not been able to offset their decline in tea plucking by spending more time on non-plucking assignments. Conclusions HIV-infected workers experienced long-term income reductions before and after initiating ART. The implications of such long-term impacts in low-income countries have not been adequately addressed. PMID:23014516

  18. Silicification-induced cell aggregation for the sustainable production of H2 under aerobic conditions.

    PubMed

    Xiong, Wei; Zhao, Xiaohong; Zhu, Genxing; Shao, Changyu; Li, Yaling; Ma, Weimin; Xu, Xurong; Tang, Ruikang

    2015-10-01

    Photobiological hydrogen production is of great importance because of its promise for generating clean renewable energy. In nature, green algae cannot produce hydrogen as a result of the extreme sensitivity of hydrogenase to oxygen. However, we find that silicification-induced green algae aggregates can achieve sustainable photobiological hydrogen production even under natural aerobic conditions. The core-shell structure of the green algae aggregates creates a balance between photosynthetic electron generation and hydrogenase activity, thus allowing the production of hydrogen. This finding provides a viable pathway for the solar-driven splitting of water into hydrogen and oxygen to develop green energy alternatives by using rationally designed cell-material complexes. PMID:26302695

  19. Identification and Analysis of Labor Productivity Components Based on ACHIEVE Model (Case Study: Staff of Kermanshah University of Medical Sciences)

    PubMed Central

    Ziapour, Arash; Khatony, Alireza; Kianipour, Neda; Jafary, Faranak

    2015-01-01

    Identification and analysis of the components of labor productivity based on ACHIEVE model was performed among employees in different parts of Kermanshah University of Medical Sciences in 2014. This was a descriptive correlational study in which the population consisted of 270 working personnel in different administrative groups (contractual, fixed- term and regular) at Kermanshah University of Medical Sciences (872 people) that were selected among 872 people through stratified random sampling method based on Krejcie and Morgan sampling table. The survey tool included labor productivity questionnaire of ACHIEVE. Questionnaires were confirmed in terms of content and face validity, and their reliability was calculated using Cronbach’s alpha coefficient. The data were analyzed by SPSS-18 software using descriptive and inferential statistics. The mean scores for labor productivity dimensions of the employees, including environment (environmental fit), evaluation (training and performance feedback), validity (valid and legal exercise of personnel), incentive (motivation or desire), help (organizational support), clarity (role perception or understanding), ability (knowledge and skills) variables and total labor productivity were 4.10±0.630, 3.99±0.568, 3.97±0.607, 3.76±0.701, 3.63±0.746, 3.59±0.777, 3.49±0.882 and 26.54±4.347, respectively. Also, the results indicated that the seven factors of environment, performance assessment, validity, motivation, organizational support, clarity, and ability were effective in increasing labor productivity. The analysis of the current status of university staff in the employees’ viewpoint suggested that the two factors of environment and evaluation, which had the greatest impact on labor productivity in the viewpoint of the staff, were in a favorable condition and needed to be further taken into consideration by authorities. PMID:25560364

  20. Chiroptical spectroscopy of natural products: avoiding the aggregation effects of chiral carboxylic acids.

    PubMed

    Polavarapu, Prasad L; Donahue, Emily A; Hammer, Karissa C; Raghavan, Vijay; Shanmugam, Ganesh; Ibnusaud, Ibrahim; Nair, Divya S; Gopinath, Chithra; Habel, Deenamma

    2012-08-24

    Determination of the absolute configurations and predominant conformations of chiral natural products, occurring as carboxylic acids, using chiroptical spectroscopic methods becomes challenging due to the formation of solute aggregates (in the form of dimers, etc.) and/or solute-solvent complexes resulting from intermolecular hydrogen bonding with solvent. A hypothesis that such aggregation effects can be avoided by using corresponding sodium salts or acid anhydrides for chiroptical spectroscopic measurements has been tested. For this purpose, vibrational circular dichroism, electronic circular dichroism, and optical rotatory dispersion spectra for disodium salts of two natural products, hibiscus acid and garcinia acid, and the anhydride of acetylated garcinia acid have been measured. These experimental spectra are analyzed in combination with quantum chemical calculations of corresponding spectra. The spectral analysis for sodium salts and anhydride turned out to be simpler, suggesting that the conversion of carboxylic acids to corresponding salts or anhydride can be advantageous for the application of chiroptical spectroscopy. PMID:22877358

  1. Process for producing an aggregate suitable for inclusion into a radiation shielding product

    DOEpatents

    Lessing, Paul A.; Kong, Peter C.

    2000-01-01

    The present invention is directed to methods for converting depleted uranium hexafluoride to a stable depleted uranium silicide in a one-step reaction. Uranium silicide provides a stable aggregate material that can be added to concrete to increase the density of the concrete and, consequently, shield gamma radiation. As used herein, the term "uranium silicide" is defined as a compound generically having the formula U.sub.x Si.sub.y, wherein the x represents the molecules of uranium and the y represent the molecules of silicon. In accordance with the present invention, uranium hexafluoride is converted to a uranium silicide by contacting the uranium hexafluoride with a silicon-containing material at a temperature in a range between about 1450.degree. C. and about 1750.degree. C. The stable depleted uranium silicide is included as an aggregate in a radiation shielding product, such as a concrete product.

  2. Construction aggregates

    USGS Publications Warehouse

    Langer, W.H.; Tepordei, V.V.; Bolen, W.P.

    2000-01-01

    Construction aggregates consist primarily of crushed stone and construction sand and gravel. Total estimated production of construction aggregates increased in 1999 by about 2% to 2.39 Gt (2.64 billion st) compared with 1998. This record production level continued an expansion that began in 1992. By commodities, crushed stone production increased 3.3%, while sand and gravel production increased by about 0.5%.

  3. Recycling of quarry waste as part of sustainable aggregate production: Norwegian and Italian point of view

    NASA Astrophysics Data System (ADS)

    Antonella Dino, Giovanna; Willy Danielsen, Svein; Chiappino, Claudia; Primavori, Piero; Engelsen, Christian John

    2016-04-01

    Resource preservation is one of the main challenges in Europe, together with waste management and recycling; recently several researchers are interested in the recovering of critical raw materials and secondary raw materials from landfill. Aggregate supply, even if it is not "critical" sensus stricto (s.s.), is one of the European priorities (low value but high volume needs). On the other side, the management of quarry waste , mainly from dimension stones, but also as fines from aggregate crushing, is still a matter of concern. Such materials are managed in different ways both locally and nationwide, and often they are landfilled, because of an unclear legislation and a general lack of data. Most of time the local authorities adopt the maximum precaution principle or the enterprises find it little profitable to recover them, so that the sustainable recycling of such material is not valued. Several studies have shown, depending on the material specific characteristics, the viability of recycling quarry waste into new raw materials used in glass and ceramic industries, precast concrete production, infrastructures etc. (Loudes et al. 2012, Dino&Marian 2015, Bozzola et al 2012, Dino et al. 2012, etc.). Thus, aggregate production may be one of the profitable ways to use quarry waste and is falling under the priority of EU (aggregate supply). Positive economic and environmental effects are likely to be achieved by systematic recycling of quarry waste planned by industries (industrial planning) and public authorities (national and local planning of aggregate exploitation). Today, the recycling level varies to a great extent and systematic recovery is not common among European Countries. In Italy and Norway no significant incentives on recycling or systematic approaches for local aggregate exploitation exist. The environmental consequences can be overexploitation of the natural resources, land take for the landfills, environmental contamination and landscape alteration by

  4. Effect of growth rate on TEP production and aggregation by Thalassiosira weissflogii

    NASA Astrophysics Data System (ADS)

    Chen, J.; Thornton, D. C.

    2012-12-01

    Aggregation into larger particles is important in carbon cycling as it affects the vertical flux of carbon through the water column and the efficiency of the biological carbon pump. Thalassiosira weissflogii was grown in semi-continuous culture at a sequence of growth rates to test the hypothesis that growth rate affects the production of transparent exopolymer particles (TEP) by diatoms. As the growth rate increased, steady-state cell abundances decreased and cell volume increased. Carbohydrate concentration per cell was positively correlated with growth rate due to the larger volume of cells at higher growth rates. TEP particle concentration decreased with increasing growth rate. However the mean size of individual TEP particles and TEP production rate increased with increasing growth rate. Therefore, the total area of TEP was the same in all cultures, irrespective of growth rate. SYTOX green staining showed that the relative permeability of cells increased with decreasing growth rate, indicating that slow growing cells may potentially leak more dissolved organic matter into the surrounding environment. There were larger aggregates in cultures grown at relatively high growth rates. These data show that diatom growth rate affected TEP production, particle stickiness, and aggregates formation. Image of TEP

  5. Application of simulated annealing to solve multi-objectives for aggregate production planning

    NASA Astrophysics Data System (ADS)

    Atiya, Bayda; Bakheet, Abdul Jabbar Khudhur; Abbas, Iraq Tereq; Bakar, Mohd. Rizam Abu; Soon, Lee Lai; Monsi, Mansor Bin

    2016-06-01

    Aggregate production planning (APP) is one of the most significant and complicated problems in production planning and aim to set overall production levels for each product category to meet fluctuating or uncertain demand in future. and to set decision concerning hiring, firing, overtime, subcontract, carrying inventory level. In this paper, we present a simulated annealing (SA) for multi-objective linear programming to solve APP. SA is considered to be a good tool for imprecise optimization problems. The proposed model minimizes total production and workforce costs. In this study, the proposed SA is compared with particle swarm optimization (PSO). The results show that the proposed SA is effective in reducing total production costs and requires minimal time.

  6. Synthesis of the aggregation pheromone of the Colorado potato beetle from its degradation product.

    PubMed

    Wacławczyk-Biedroń, Weronika; Frąckowiak-Wojtasek, Bożena; Strub, Daniel; Rzechak, Magdalena; Wojtasek, Hubert

    2015-09-01

    Incubation of the Colorado potato beetle aggregation pheromone, (S)-1,3-dihydroxy-3,7-dimethyl-6-octen-2-one, with antennal or leg extracts from this beetle gave 6-methyl-5-hepten-2-one as the major product. This ketone was used as a substrate in a stereoselective synthesis of the pheromone. It was attached to the butanediacetal of glycolic acid with good stereoselectivity and the desired isomer was further enriched by purification of the product of this reaction on silica gel. PMID:26169127

  7. Synthesis of the aggregation pheromone of the Colorado potato beetle from its degradation product.

    PubMed

    Wacławczyk-Biedroń, Weronika; Frąckowiak-Wojtasek, Bożena; Strub, Daniel; Rzechak, Magdalena; Wojtasek, Hubert

    2015-09-01

    Incubation of the Colorado potato beetle aggregation pheromone, (S)-1,3-dihydroxy-3,7-dimethyl-6-octen-2-one, with antennal or leg extracts from this beetle gave 6-methyl-5-hepten-2-one as the major product. This ketone was used as a substrate in a stereoselective synthesis of the pheromone. It was attached to the butanediacetal of glycolic acid with good stereoselectivity and the desired isomer was further enriched by purification of the product of this reaction on silica gel.

  8. Aggregate consumer exposure to UV filter ethylhexyl methoxycinnamate via personal care products.

    PubMed

    Manová, Eva; von Goetz, Natalie; Hungerbuehler, Konrad

    2015-01-01

    Ultraviolet (UV) filters are substances designed to protect our skin from UV-induced damage and can be found in many categories of personal care products (PCPs). The potential endocrine-disrupting effects attributed to UV filter ethylhexyl methoxycinnamate (EHMC) are being debated. We evaluated the aggregate exposure of the Swiss-German population (N=1196; ages ≤1-97years) to EHMC via the use of PCPs; thus we provide the first comprehensive information about the current EHMC exposure sources and aggregate exposure levels. In our probabilistic modeling method performed at an individual level, PCP use data obtained by a postal questionnaire were linked to concentration data on EHMC gained from chemical analyses of PCPs used by the questionnaire respondents. The modeled median and 99.9th percentile of the internal aggregate exposure for the general population were 0.012 and 0.873mgday(-1)kg(-1) and 0.008 and 0.122mgday(-1)kg(-1) for the summer/autumn and winter/spring period, respectively. The major contributors to internal aggregate exposure were sunscreen products in summer/autumn (females: 64%; males: 85%; children aged ≤12years 93%). In winter/spring, lip care dominated for females (30%) and sunscreen for males (38%) and children aged ≤12years (50%). Overall, the internal aggregate exposure estimates for the studied population are shown to be below the Derived No Effect Level (DNEL) for EHMC i.e., the level of exposure above which humans should not be exposed; however, when an intense short-term exposure via sunscreen is accounted for during a sunbathing day, at the high-end percentiles (99.9th) the predicted aggregate exposure exceeds the DNEL for thyroid-disrupting effects such as for children aged ≤4years, who might be particularly susceptible to endocrine disrupting events. It is nevertheless critical to acknowledge that quantitative data on transdermal penetration of EHMC from PCPs are currently insufficient. Since long-term effects of endocrine

  9. Aggregate consumer exposure to UV filter ethylhexyl methoxycinnamate via personal care products.

    PubMed

    Manová, Eva; von Goetz, Natalie; Hungerbuehler, Konrad

    2015-01-01

    Ultraviolet (UV) filters are substances designed to protect our skin from UV-induced damage and can be found in many categories of personal care products (PCPs). The potential endocrine-disrupting effects attributed to UV filter ethylhexyl methoxycinnamate (EHMC) are being debated. We evaluated the aggregate exposure of the Swiss-German population (N=1196; ages ≤1-97years) to EHMC via the use of PCPs; thus we provide the first comprehensive information about the current EHMC exposure sources and aggregate exposure levels. In our probabilistic modeling method performed at an individual level, PCP use data obtained by a postal questionnaire were linked to concentration data on EHMC gained from chemical analyses of PCPs used by the questionnaire respondents. The modeled median and 99.9th percentile of the internal aggregate exposure for the general population were 0.012 and 0.873mgday(-1)kg(-1) and 0.008 and 0.122mgday(-1)kg(-1) for the summer/autumn and winter/spring period, respectively. The major contributors to internal aggregate exposure were sunscreen products in summer/autumn (females: 64%; males: 85%; children aged ≤12years 93%). In winter/spring, lip care dominated for females (30%) and sunscreen for males (38%) and children aged ≤12years (50%). Overall, the internal aggregate exposure estimates for the studied population are shown to be below the Derived No Effect Level (DNEL) for EHMC i.e., the level of exposure above which humans should not be exposed; however, when an intense short-term exposure via sunscreen is accounted for during a sunbathing day, at the high-end percentiles (99.9th) the predicted aggregate exposure exceeds the DNEL for thyroid-disrupting effects such as for children aged ≤4years, who might be particularly susceptible to endocrine disrupting events. It is nevertheless critical to acknowledge that quantitative data on transdermal penetration of EHMC from PCPs are currently insufficient. Since long-term effects of endocrine

  10. Utilization of lignite power generation residues for the production of lightweight aggregates.

    PubMed

    Anagnostopoulos, Iason M; Stivanakis, Victor E

    2009-04-15

    A novel process is proposed for the utilization of lignite combustion solid residues in the production of inflammable lightweight aggregates (LWA). The process consists of two stages, pelletization and sintering, and carbon contained in BA was used as the process fuel. The main residues bottom ash (BA) and fly ash (FA) from Megalopolis power plant were characterized, mixed in different proportions and treated through pelletization and sintering process. Sintering benefits from combustion of BA carbon content and the product is a hardened porous cake. The energy required for achievement of high temperatures, in the range of 1250 degrees C, was offered by carbon combustion and CO(2) evolution is responsible for porous structure formation. Selected physical properties of sintered material relevant to use as lightweight aggregates were determined, including bulk density, porosity and water absorption. Bulk density varies from 0.83 to 0.91 g/cm(3), porosity varies from 60% to 64% and water absorption varies from 66% to 80%. LWA formed is used for the production of lightweight aggregate concrete (LWAC). Thermal conductivity coefficient varies from 0.25 to 0.37 W/mK (lower than maximum limit 0.43 W/mK) and compressive strength varies from 19 to 23 MPa (higher than minimum limit 17 MPa). The results indicate that sintering of lignite combustion residues is an efficient method of utilization of carbon containing BA and production of LWA for structural and insulating purposes. Carbon content of BA is a key factor in LWA production. Finally, this research work comprises the first proposed application for utilization of BA in Greece. PMID:18804911

  11. Collaborative production and experimental labor: two models of dissertation authorship in the eighteenth century.

    PubMed

    Chang, Ku-ming Kevin

    2010-12-01

    This article examines two early modern models of dissertation authorship that both relied on extensive collaboration between the degree candidate and his supervisor. The dissertation conducted on the traditional model, practiced until the eighteenth century at German universities, was a joint product of the supervisor, who prepared the thesis in writing, and the degree candidate, who defended it in the oral disputation. The two collaborators shared the credit for a successfully defended thesis in different forms: right for public recognition and rights to use and reproduce the thesis. Instead of sharing the credit as two equal partners, each of them took advantage of his credit in ways that benefited his status. In the model that Albrecht von Haller introduced at Göttingen, the supervisor provided the student with a laboratory and experimental training, while the degree candidate wrote a thesis by himself based on the experiments he carried out, and defended the thesis without the supervisor chairing the disputation. The Haller model reveals two new elements that heralded the development of modern scientific education: divisibility of laboratory labor between the student's experimentation and the research program to which it belongs; and feasibility of the requirement of experimental work in return for the exclusive authorship of the doctoral thesis.

  12. Inducing labor

    MedlinePlus

    Labor induction ... are many reasons why you may need labor induction. The induction of labor may be started before any signs ... Wing DA, Farinelli CK. Abnormal labor and induction of labor. In: Gabbe ... Pregnancies . 6th ed. Philadelphia, PA: Elsevier Saunders; ...

  13. Construction aggregates

    USGS Publications Warehouse

    Tepordei, V.V.

    1994-01-01

    Part of a special section on industrial minerals in 1993. The 1993 production of construction aggregates increased 6.3 percent over the 1992 figure, to reach 2.01 Gt. This represents the highest estimated annual production of combined crushed stone and construction sand and gravel ever recorded in the U.S. The outlook for construction aggregates and the issues facing the industry are discussed.

  14. Strategies for the assessment of protein aggregates in pharmaceutical biotech product development.

    PubMed

    den Engelsman, John; Garidel, Patrick; Smulders, Ronald; Koll, Hans; Smith, Bryan; Bassarab, Stefan; Seidl, Andreas; Hainzl, Otmar; Jiskoot, Wim

    2011-04-01

    Within the European Immunogenicity Platform (EIP) ( http://www.e-i-p.eu ), the Protein Characterization Subcommittee (EIP-PCS) has been established to discuss and exchange experience of protein characterization in relation to unwanted immunogenicity. In this commentary, we, as representatives of EIP-PCS, review the current state of methods for analysis of protein aggregates. Moreover, we elaborate on why these methods should be used during product development and make recommendations to the biotech community with regard to strategies for their application during the development of protein therapeutics.

  15. Preterm Labor

    MedlinePlus

    Preterm labor is labor that starts before 37 completed weeks of pregnancy. It can lead to premature ... babies may face serious health risks. Symptoms of preterm labor include Contractions every 10 minutes or more ...

  16. Utilization of Illinois slags for the production of ultra-lightweight aggregates

    SciTech Connect

    Choudhry, V. ); Zimmerle, T. ); Banerjee, D.D. )

    1993-01-01

    The objective of this program is to demonstrate that solid residues (slag) from the gasification of Illinois coals can be utilized to manufacture ultra-lightweight aggregates (ULWA). Conventional ULWAs are made by pyroprocessing perlite ores and have unit weights in the range of 3--15 lb/ft[sup 3]. In a previous project, Praxis Engineers demonstrated at the pilot scale that lightweight aggregates with unit weights of 40--55 lb/ ft[sup 3] can be produced from Illinois coal slags, which is suitable for making lightweight cement concrete and precast blocks. These tests also indicated that a product with a unit weight of less than 25 lb/ft[sup 3] could be produced from slag. This project is aimed at testing the potential for producing ULWA from Illinois coal slags. Target applications include loose fill insulation, insulating concrete, lightweight precast products such as concrete blocks and rooftiles, and filtration media. Laboratory- and pilot-scale testing is being conducted in Phase I to identify operating conditions for the expansion of Illinois slags to produce ULWA. Following this, a large batch of expanded slag will be produced, for evaluation in various applications in Phase II.

  17. Upright posture and maximal exercise increase platelet aggregability and prostacyclin production in healthy male subjects

    PubMed Central

    Feng, D. L.; Murillo, J.; Jadhav, P.; McKenna, C.; Gebara, O. C.; Lipinska, I.; Muller, J. E.; Tofler, G. H.

    1999-01-01

    BACKGROUND: It is well accepted that heavy physical exertion can trigger the onset of myocardial infarction, but the mechanism is uncertain. As platelet and endothelial function play an important role in thrombotic events, platelet and prostacyclin responses to maximal treadmill exercise were studied. METHODS/RESULTS: The study subjects were 40 healthy men, mean (SEM) age 29 (5) years. Platelet aggregation was measured on a four channel aggregometer. Plasma 6-keto- prostaglandin F1alpha was analysed using an enzyme immunoassay technique. Upright posture and exercise produced an increase in platelet aggregability, as indicated by a fall in the threshold concentration of adrenaline (epinephrine) from 7.6 (1.5) microM at rest to 4.3 (1.0) microM after exercise (p = 0.002). The collagen lag time became significantly shorter with exercise (from 79.1 (3.1) seconds at rest to 71.9 (2.6) seconds after exercise, p = 0.003). Exercise was also associated with a 55% increase in plasma 6-keto-prostaglandin F1alpha (from 38.1 (75%CI 29.0 to 46.5) pg/ml at rest to 59.2 (47.3 to 66.8) pg/ml after exercise, p<0.001). CONCLUSIONS: In healthy male subjects, upright posture and maximal exercise increased platelet aggregability but this increase was counteracted by an increase in prostacyclin production. In patients with endothelial dysfunction, a reduced prostacyclin response to exercise may promote a transient prothrombotic imbalance that may trigger cardiovascular disease onset. 


 PMID:10597849

  18. Trends in the Higher Education Labor Force: Identifying Changes in Worker Composition and Productivity

    ERIC Educational Resources Information Center

    Bennett, Daniel L.

    2009-01-01

    Higher education is a labor-intensive industry whose primary service, instruction, is delivered by a lecturer, accompanied by administrative support and various other services. Growing student enrollment necessitates some additional staffing; however, one would think that the recent and ongoing technological boom would have lessened the labor…

  19. Passion Work: The Joint Production of Emotional Labor in Professional Wrestling

    ERIC Educational Resources Information Center

    Smith, R. Tyson

    2008-01-01

    This paper presents a case of jointly produced passion work. Passion work is emotional labor designed to elicit a strong response from subjects through an impression of extreme states such as pain, agony, or suffering. Based on an ethnographic investigation of professional wrestling participants, this study analyzes the backstage emotion teamwork…

  20. Sound production by dusky grouper Epinephelus marginatus at spawning aggregation sites.

    PubMed

    Bertucci, F; Lejeune, P; Payrot, J; Parmentier, E

    2015-08-01

    Sound production by the dusky grouper Epinephelus marginatus was monitored both in captivity and at two Mediterranean spawning sites during the summers of 2012 and 2013. The results of long-term passive acoustic recordings provide for the first time a description of the sounds produced by E. marginatus. Two types of sounds were mainly recorded and consisted of low-frequency booms that can be produced singly or in series with dominant frequencies below 100 Hz. Recordings in captivity validated these sounds as belonging to E. marginatus and suggested that they may be associated with reproductive displays usually performed during early stages of courtship behaviour. This study also allowed the identification of a third, low-frequency growl-like type of sound typically found in other grouper species. These growls were, however, not recorded in tanks and it is cautiously proposed that they are produced by E. marginatus. Acoustic signals attributed to E. marginatus were produced throughout the spawning season, with a diel pattern showing an increase before dusk, i.e., from 1900 to 2200 hours, before decreasing until the morning. The occurrence of sounds during the spawning season of this species suggests that they are probably involved in social activity occurring close to aggregation sites. Passive acoustics offer a helpful tool to monitor aggregation sites of this emblematic species in order to improve conservation efforts. PMID:26177857

  1. Soil aggregate stability and grassland productivity associations in a northern mixed-grass prairie

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Soil (aggregate) stability is widely used as an indicator of soil and rangeland health. The empirical evidence justifying soil aggregate stability as an indicator of rangeland health, however, is thin and confusing. Here we revisit the hypothesis that soil aggregate stability is positively correla...

  2. The Optimum Production Method for Quality Improvement of Recycled Aggregates Using Sulfuric Acid and the Abrasion Method

    PubMed Central

    Kim, Haseog; Park, Sangki; Kim, Hayong

    2016-01-01

    There has been increased deconstruction and demolition of reinforced concrete structures due to the aging of the structures and redevelopment of urban areas resulting in the generation of massive amounts of construction. The production volume of waste concrete is projected to increase rapidly over 100 million tons by 2020. However, due to the high cement paste content, recycled aggregates have low density and high absorption ratio. They are mostly used for land reclamation purposes with low added value instead of multiple approaches. This study was performed to determine an effective method to remove cement paste from recycled aggregates by using the abrasion and substituting the process water with acidic water. The aim of this study is to analyze the quality of the recycled fine aggregates produced by a complex method and investigate the optimum manufacturing conditions for recycled fine aggregates based on the design of experiment. The experimental parameters considered were water ratio, coarse aggregate ratio, and abrasion time and, as a result of the experiment, data concerning the properties of recycled sand were obtained. It was found that high-quality recycled fine aggregates can be obtained with 8.57 min of abrasion-crusher time and a recycled coarse aggregate ratio of over 1.5. PMID:27483298

  3. The Optimum Production Method for Quality Improvement of Recycled Aggregates Using Sulfuric Acid and the Abrasion Method.

    PubMed

    Kim, Haseog; Park, Sangki; Kim, Hayong

    2016-01-01

    There has been increased deconstruction and demolition of reinforced concrete structures due to the aging of the structures and redevelopment of urban areas resulting in the generation of massive amounts of construction. The production volume of waste concrete is projected to increase rapidly over 100 million tons by 2020. However, due to the high cement paste content, recycled aggregates have low density and high absorption ratio. They are mostly used for land reclamation purposes with low added value instead of multiple approaches. This study was performed to determine an effective method to remove cement paste from recycled aggregates by using the abrasion and substituting the process water with acidic water. The aim of this study is to analyze the quality of the recycled fine aggregates produced by a complex method and investigate the optimum manufacturing conditions for recycled fine aggregates based on the design of experiment. The experimental parameters considered were water ratio, coarse aggregate ratio, and abrasion time and, as a result of the experiment, data concerning the properties of recycled sand were obtained. It was found that high-quality recycled fine aggregates can be obtained with 8.57 min of abrasion-crusher time and a recycled coarse aggregate ratio of over 1.5. PMID:27483298

  4. The Optimum Production Method for Quality Improvement of Recycled Aggregates Using Sulfuric Acid and the Abrasion Method.

    PubMed

    Kim, Haseog; Park, Sangki; Kim, Hayong

    2016-01-01

    There has been increased deconstruction and demolition of reinforced concrete structures due to the aging of the structures and redevelopment of urban areas resulting in the generation of massive amounts of construction. The production volume of waste concrete is projected to increase rapidly over 100 million tons by 2020. However, due to the high cement paste content, recycled aggregates have low density and high absorption ratio. They are mostly used for land reclamation purposes with low added value instead of multiple approaches. This study was performed to determine an effective method to remove cement paste from recycled aggregates by using the abrasion and substituting the process water with acidic water. The aim of this study is to analyze the quality of the recycled fine aggregates produced by a complex method and investigate the optimum manufacturing conditions for recycled fine aggregates based on the design of experiment. The experimental parameters considered were water ratio, coarse aggregate ratio, and abrasion time and, as a result of the experiment, data concerning the properties of recycled sand were obtained. It was found that high-quality recycled fine aggregates can be obtained with 8.57 min of abrasion-crusher time and a recycled coarse aggregate ratio of over 1.5.

  5. Photo-fermentative bacteria aggregation triggered by L-cysteine during hydrogen production

    PubMed Central

    2013-01-01

    Background Hydrogen recovered from organic wastes and solar energy by photo-fermentative bacteria (PFB) has been suggested as a promising bioenergy strategy. However, the use of PFB for hydrogen production generally suffers from a serious biomass washout from photobioreactor, due to poor flocculation of PFB. In the continuous operation, PFB cells cannot be efficiently separated from supernatant and rush out with effluent from reactor continuously, which increased the effluent turbidity, meanwhile led to increases in pollutants. Moreover, to replenish the biomass washout, substrate was continuously utilized for cell growth rather than hydrogen production. Consequently, the poor flocculability not only deteriorated the effluent quality, but also decreased the potential yield of hydrogen from substrate. Therefore, enhancing the flocculability of PFB is urgent necessary to further develop photo-fermentative process. Results Here, we demonstrated that L-cysteine could improve hydrogen production of Rhodopseudomonas faecalis RLD-53, and more importantly, simultaneously trigger remarkable aggregation of PFB. Experiments showed that L-cysteine greatly promoted the production of extracellular polymeric substances, especially secretion of protein containing more disulfide bonds, and help for enhancement stability of floc of PFB. Through formation of disulfide bonds, L-cysteine not only promoted production of EPS, in particular the secretion of protein, but also stabilized the final confirmation of protein in EPS. In addition, the cell surface elements and functional groups, especially surface charged groups, have also been changed by L-cysteine. Consequently, absolute zeta potential reached a minimum value at 1.0 g/l of L-cysteine, which obviously decreased electrostatic repulsion interaction energy based on DLVO theory. Total interaction energy barrier decreased from 389.77 KT at 0.0 g/l of L-cysteine to 127.21 kT at 1.0 g/l. Conclusions Thus, the strain RLD-53 overcame the

  6. The labor force of the future.

    PubMed

    Norwood, J L

    1987-07-01

    In the decades ahead, the US labor force will reflect changes in the industrial structure, with declines in some manufacturing industries and expansion in service industries. The services sector is so diverse that the jobs within it cannot be categorized as either high wage or low wage. The service-producing sector employs 85% of professional specialty workers in the US. In general, information on compensation trends indicates that greater increases in compensation have occurred for workers in service-producing as opposed to goods-producing industries. The increase in service sector jobs has created opportunities for women to enter the labor force and, at present, 5 out of 6 women work in this sector compared to fewer than 2 out of 3 men. Productivity growth rates in the service-producing industries vary substantially and are strongly affected by the business cycle. Central to employment opportunities in the years ahead will be the effect of new technology. To date, the aggregate effect of new technology has been increased employment and higher living standards. Although retraining programs should be in place, the scenario of a huge technology-created labor surplus seems unlikely. In fact, a more likely problem is a shortage of labor resulting from earlier labor force withdrawal and demographic aging of the population. Those in the 25-54-year age group will represent a larger share of the labor force in the years ahead. In addition, blacks are expected to account for 20% of the labor force growth in the next decade. Finally, given increasing labor force participation rates among mothers, employers may have to provide more flexible work schedules, assistance with day care, and more attractive benefits packages. PMID:12314853

  7. Marine Data Management within the EMODNet Chemistry project: data aggregation, quality control and products preparation.

    NASA Astrophysics Data System (ADS)

    Iona, Athanasia Sissy; Karagevrekis, Pelopidas; Balopoulou, Stavroula; Giorgetti, Alessandra; Schaap, Dick

    2015-04-01

    The European Commission in response to the EU Green Paper for an integrated maritime policy has initiated the European Marine Observation and Data Network (EMODnet) to improve Europe's marine data infrastructure, increase the availability of high quality data and assemble them under a common framework. In 2009, six service contracts were launched by DG-MARE for creating the pilot components of the network and setting up thematic web portals covering selected marine basins. In 2012, a second call was opened by DG-MARE to continue the further expand the pilot portals in terms of geographical coverage and range of products and concluded in seven service contracts for: bathymetry, geology, physical habitats, chemistry, biology, physics and human activities. Supporting activities are also foreseen to examine how the portals meet the needs of users from industry, public authorities and scientists, to identify data gaps and arguments why these gaps should be filled in future monitoring. The second EMODNet Chemistry proposal has been prepared and submitted by the SeaDataNet consortium which is the leading data management network in Europe, covering all sea basins in European waters with data input from almost all coastal states. It is the same consortium that had been awarded the first call for the preparatory actions and has been extended with new partners. EMODnet Chemistry (www.emodnet-chemistry.eu/) is focusing on measurement data for groups of chemical variables in water, sediments and biota with relevance to the Marine Strategy Framework Directive. Five regional groups corresponding to the five MSFD regions are performing quality control and aggregation on the data gathered from many distributed data providers of the SeaDataNet infrastructure in order to generate regional harmonized, aggregated and validated data sets for selected groups of chemicals variables. Then these data sets are used to prepare interpolated maps of chemical variables per region over time and

  8. The production of synthetic aggregate from a quarry waste using an innovative style rotary kiln.

    PubMed

    Wainwright, R J; Cresswell, D J F; van der Sloot, H A

    2002-06-01

    The large volumes of wastes generated by industrialised society has led to efforts to find practical uses for these wastes, whilst also offsetting the consumption of natural resources. This paper describes the use of an innovative rotary kiln to produce synthetic aggregates from a variety of waste streams. The main waste used was a quarry fines which was blended with either paper sludge, clay, or a dredged harbour sediment. The different combinations were extruded and fired in the kiln to produce a material suitable for natural aggregate replacement. Two of the synthetic aggregates produced were tested by incorporation in to concrete as coarse aggregate replacement. The concrete 28-day compressive strengths achieved were above 40 N mm(-2) and compared favourably with control concretes made with natural aggregates and a commercially available lightweight aggregate (Lytag). Leaching tests have also been carried out to assess the potential environmental impact of utilisation. Although not finalised, these tests have also given favourable results.

  9. The production of synthetic aggregate from a quarry waste using an innovative style rotary kiln.

    PubMed

    Wainwright, R J; Cresswell, D J F; van der Sloot, H A

    2002-06-01

    The large volumes of wastes generated by industrialised society has led to efforts to find practical uses for these wastes, whilst also offsetting the consumption of natural resources. This paper describes the use of an innovative rotary kiln to produce synthetic aggregates from a variety of waste streams. The main waste used was a quarry fines which was blended with either paper sludge, clay, or a dredged harbour sediment. The different combinations were extruded and fired in the kiln to produce a material suitable for natural aggregate replacement. Two of the synthetic aggregates produced were tested by incorporation in to concrete as coarse aggregate replacement. The concrete 28-day compressive strengths achieved were above 40 N mm(-2) and compared favourably with control concretes made with natural aggregates and a commercially available lightweight aggregate (Lytag). Leaching tests have also been carried out to assess the potential environmental impact of utilisation. Although not finalised, these tests have also given favourable results. PMID:12152896

  10. Adherent-Invasive Escherichia coli Production of Cellulose Influences Iron-Induced Bacterial Aggregation, Phagocytosis, and Induction of Colitis.

    PubMed

    Ellermann, Melissa; Huh, Eun Young; Liu, Bo; Carroll, Ian M; Tamayo, Rita; Sartor, R Balfour

    2015-10-01

    Adherent-invasive Escherichia coli (AIEC), a functionally distinct subset of resident intestinal E. coli associated with Crohn's disease, is characterized by enhanced epithelial adhesion and invasion, survival within macrophages, and biofilm formation. Environmental factors, such as iron, modulate E. coli production of extracellular structures, which in turn influence the formation of multicellular communities, such as biofilms, and bacterial interactions with host cells. However, the physiological and functional responses of AIEC to variable iron availability have not been thoroughly investigated. We therefore characterized the impact of iron on the physiology of AIEC strain NC101 and subsequent interactions with macrophages. Iron promoted the cellulose-dependent aggregation of NC101. Bacterial cells recovered from the aggregates were more susceptible to phagocytosis than planktonic cells, which corresponded with the decreased macrophage production of the proinflammatory cytokine interleukin-12 (IL-12) p40. Prevention of aggregate formation through the disruption of cellulose production reduced the phagocytosis of iron-exposed NC101. In contrast, under iron-limiting conditions, where NC101 aggregation is not induced, the disruption of cellulose production enhanced NC101 phagocytosis and decreased macrophage secretion of IL-12 p40. Finally, abrogation of cellulose production reduced NC101 induction of colitis when NC101 was monoassociated in inflammation-prone Il10(-/-) mice. Taken together, our results introduce cellulose as a novel physiological factor that impacts host-microbe-environment interactions and alters the proinflammatory potential of AIEC.

  11. Construction aggregates

    USGS Publications Warehouse

    Nelson, T.I.; Bolen, W.P.

    2007-01-01

    Construction aggregates, primarily stone, sand and gravel, are recovered from widespread naturally occurring mineral deposits and processed for use primarily in the construction industry. They are mined, crushed, sorted by size and sold loose or combined with portland cement or asphaltic cement to make concrete products to build roads, houses, buildings, and other structures. Much smaller quantities are used in agriculture, cement manufacture, chemical and metallurgical processes, glass production and many other products.

  12. Labor Force

    ERIC Educational Resources Information Center

    Occupational Outlook Quarterly, 2012

    2012-01-01

    The labor force is the number of people ages 16 or older who are either working or looking for work. It does not include active-duty military personnel or the institutionalized population, such as prison inmates. Determining the size of the labor force is a way of determining how big the economy can get. The size of the labor force depends on two…

  13. Labor Force

    ERIC Educational Resources Information Center

    Occupational Outlook Quarterly, 2010

    2010-01-01

    The labor force is the number of people aged 16 or older who are either working or looking for work. It does not include active-duty military personnel or institutionalized people, such as prison inmates. Quantifying this total supply of labor is a way of determining how big the economy can get. Labor force participation rates vary significantly…

  14. MIGRATORY LABOR IN COLORADO.

    ERIC Educational Resources Information Center

    DOUGLASS, M.R.; AND OTHERS

    CONDITIONS AND PROBLEMS RELATING TO THE EMPLOYMENT OF SEASONAL FARM WORKERS AND MIGRANTS IN COLORADO ARE PRESENTED. THE FIVE MAJOR SEASONAL FARM LABOR STATE EMPLOYMENT AREAS ARE SURVEYED ACCORDING TO (1) THE ORGANIZATION OF THE SEASONAL FARM LABOR (4) TRENDS IN AGRICULTURAL ACREAGE, PRODUCTION, AND TECHNOLOGICAL CHANGE, (5) COMMUNITY ATTITUDES AND…

  15. Use of an aggregate exposure model to estimate consumer exposure to fragrance ingredients in personal care and cosmetic products.

    PubMed

    Safford, B; Api, A M; Barratt, C; Comiskey, D; Daly, E J; Ellis, G; McNamara, C; O'Mahony, C; Robison, S; Smith, B; Thomas, R; Tozer, S

    2015-08-01

    Ensuring the toxicological safety of fragrance ingredients used in personal care and cosmetic products is essential in product development and design, as well as in the regulatory compliance of the products. This requires an accurate estimation of consumer exposure which, in turn, requires an understanding of consumer habits and use of products. Where ingredients are used in multiple product types, it is important to take account of aggregate exposure in consumers using these products. This publication investigates the use of a newly developed probabilistic model, the Creme RIFM model, to estimate aggregate exposure to fragrance ingredients using the example of 2-phenylethanol (PEA). The output shown demonstrates the utility of the model in determining systemic and dermal exposure to fragrances from individual products, and aggregate exposure. The model provides valuable information not only for risk assessment, but also for risk management. It should be noted that data on the concentrations of PEA in products used in this article were obtained from limited sources and not the standard, industry wide surveys typically employed by the fragrance industry and are thus presented here to illustrate the output and utility of the newly developed model. They should not be considered an accurate representation of actual exposure to PEA.

  16. Use of an aggregate exposure model to estimate consumer exposure to fragrance ingredients in personal care and cosmetic products.

    PubMed

    Safford, B; Api, A M; Barratt, C; Comiskey, D; Daly, E J; Ellis, G; McNamara, C; O'Mahony, C; Robison, S; Smith, B; Thomas, R; Tozer, S

    2015-08-01

    Ensuring the toxicological safety of fragrance ingredients used in personal care and cosmetic products is essential in product development and design, as well as in the regulatory compliance of the products. This requires an accurate estimation of consumer exposure which, in turn, requires an understanding of consumer habits and use of products. Where ingredients are used in multiple product types, it is important to take account of aggregate exposure in consumers using these products. This publication investigates the use of a newly developed probabilistic model, the Creme RIFM model, to estimate aggregate exposure to fragrance ingredients using the example of 2-phenylethanol (PEA). The output shown demonstrates the utility of the model in determining systemic and dermal exposure to fragrances from individual products, and aggregate exposure. The model provides valuable information not only for risk assessment, but also for risk management. It should be noted that data on the concentrations of PEA in products used in this article were obtained from limited sources and not the standard, industry wide surveys typically employed by the fragrance industry and are thus presented here to illustrate the output and utility of the newly developed model. They should not be considered an accurate representation of actual exposure to PEA. PMID:26071898

  17. Uncovering methods for the prevention of protein aggregation and improvement of product quality in a transient expression system.

    PubMed

    Estes, Bram; Hsu, Yueh-Rong; Tam, Lei-Ting; Sheng, Jackie; Stevens, Jennitte; Haldankar, Raj

    2015-01-01

    Mammalian expression systems are used routinely for the production of recombinant proteins as therapeutic molecules as well as research tools. Transient expression has become increasingly popular in recent years due to its rapid timeline and improvements in expression level. While improvements to transient expression systems have focused mainly on the level of protein expression, the aspect of protein quality has received little attention. The removal of undesirable products, such as aggregation, depends primarily on purification, requiring additional cumbersome steps, which can lead to a lower product yield and longer timelines. In this study, we show that reducing the level of transcription by transfecting at a lower gene dose improves the quality of secreted molecules prone to aggregation. For gene dosing to have this effect, it is critical for the carrier DNA to be an empty vector containing the same elements as the gene containing plasmid. This approach can be used in combination with a temperature shift to hypothermic conditions during production to enhance the effect. The observed improvements not only minimized aggregation levels, but also generated products with overall superior quality, including more homogeneous signal peptide cleavage and N-linked glycosylation profiles. These techniques have produced a similar improvement in product quality with a variety of other molecules, suggesting that this may be a general approach to enhance product quality from transient expression systems. PMID:25395220

  18. The Production of Inequality: The Gender Division of Labor Across the Transition to Parenthood

    PubMed Central

    Yavorsky, Jill E.; Dush, Claire M. Kamp; Schoppe-Sullivan, Sarah J.

    2015-01-01

    Using longitudinal time diary and survey data from a community sample of dual-earner couples across the transition to parenthood, the authors examined change in divisions of paid and unpaid work and assessed the accuracy of survey data for time use measurement. Mothers, according to the time diaries, shouldered the majority of child care and did not decrease their paid work hours. Furthermore, the gender gap was not present prebirth but emerged postbirth with women doing more than 2 hours of additional work per day compared to an additional 40 minutes for men. Moreover, the birth of a child magnified parents’ overestimations of work in the survey data, and had the authors relied only on survey data, gender work inequalities would not have been apparent. The findings have important implications for (a) the state of the gender revolution among couples well positioned to obtained balanced workloads and (b) the utility of survey data to measure parents’ division of labor. PMID:26430282

  19. The applicability of different waste materials for the production of lightweight aggregates.

    PubMed

    Ducman, V; Mirtic, B

    2009-08-01

    The applicability of different waste materials for the production of lightweight aggregates has been studied. The following waste materials were investigated: silica sludge, superfluous clay in the quarry, waste glass, and residue from the polishing process of different types of stone. SiC and MnO(2) were selected as foaming agents. Feldspar containing minerals and scrap glass were added in order to lower the softening point of the waste materials. The granules were prepared by mixing together finely ground waste with one or both of the selected foaming agents. The granules were then fired at different temperatures above the softening point of the glassy phase within the temperature range from 1150 to 1220 degrees C, where the foaming agent degasses, and the resulting gasses remain trapped in the glassy structure. The foaming process was observed by hot-stage microscopy. The properties of the so-obtained granules, such as their apparent density and compressive strength, were determined, and their microstructures were evaluating using SEM and polarizing microscopy. With the addition to clay of polishing residue from granite-like rocks, after firing at 1220 degrees C homogeneously porous granules with a density down to 0.42 g/cm(3) were obtained, whereas with the addition to waste silica sludge of polishing residue from granite-like rocks and waste glass with a foaming agent, after firing at 1220 degrees C densities from 0.57 to 0.82 g/cm(3) were obtained.

  20. Inhibition of platelet aggregation and reduced formation of thromboxane and lipoxygenase products in platelets by oil of cloves.

    PubMed

    Srivastava, K C; Justesen, U

    1987-09-01

    Oil of cloves (OC) was found to be a potent inhibitor of platelet aggregation induced by arachidonic acid (AA), collagen and epinephrine; in this respect it was most effective against AA-induced aggregation. Inhibition of aggregation by OC seems to be mediated through a reduced formation of thromboxane as indicated by the following experimental evidence. (i) OC inhibited TxB2 formation in intact as well as lysed platelet preparations from added arachidonate, and (ii) it inhibited the formation of TxB2 from AA-labelled platelets after activation with Ca2+-ionophore A23187. The formation of lipoxygenase derived products was dependent on the concentration of OC used; at its lower concentration their amounts increased but this was found to be reversed at higher concentrations. At all concentrations thromboxane was decreased with a concomitant increase in unused AA. PMID:3118394

  1. Expert systems and the CPI product substitution review: A needs analysis for the US Bureau of Labor Statistics

    SciTech Connect

    Arrowood, L.F.; Tonn, B.E.

    1992-02-01

    This report presents recommendations relative to the use of expert systems and machine learning techniques by the Bureau of Labor Statistics (BLS) to substantially automate product substitution decisions associated with the Consumer Price Index (CPI). Thirteen commercially available, PC-based expert system shells have received in-depth evaluations. Various machine learning techniques were also reviewed. Two recommendations are given: (1) BLS should use the expert system shell LEVEL5 OBJECT and establish a software development methodology for expert systems; and (2) BLS should undertake a small study to evaluate the potential of machine learning techniques to create and maintain the approximately 350 ELI-specific knowledge bases to be used in CPI product substitution review.

  2. Validation of an aggregate exposure model for substances in consumer products: a case study of diethyl phthalate in personal care products

    PubMed Central

    Delmaar, Christiaan; Bokkers, Bas; ter Burg, Wouter; Schuur, Gerlienke

    2015-01-01

    As personal care products (PCPs) are used in close contact with a person, they are a major source of consumer exposure to chemical substances contained in these products. The estimation of realistic consumer exposure to substances in PCPs is currently hampered by the lack of appropriate data and methods. To estimate aggregate exposure of consumers to substances contained in PCPs, a person-oriented consumer exposure model has been developed (the Probabilistic Aggregate Consumer Exposure Model, PACEM). The model simulates daily exposure in a population based on product use data collected from a survey among the Dutch population. The model is validated by comparing diethyl phthalate (DEP) dose estimates to dose estimates based on biomonitoring data. It was found that the model's estimates compared well with the estimates based on biomonitoring data. This suggests that the person-oriented PACEM model is a practical tool for assessing realistic aggregate exposures to substances in PCPs. In the future, PACEM will be extended with use pattern data on other product groups. This will allow for assessing aggregate exposure to substances in consumer products across different product groups. PMID:25352161

  3. 77 FR 59980 - Established Aggregate Production Quotas for Schedule I and II Controlled Substances and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-01

    ... 2013,'' was published in the Federal Register (77 FR 46519). That notice proposed the 2013 aggregate... g Hydroxypethidine 2 g Ibogaine 5 g Lysergic acid diethylamide (LSD) 30 g Marihuana 21,000...

  4. Glycation by Ascorbic Acid Oxidation Products Leads to the Aggregation of Lens Proteins

    PubMed Central

    Linetsky, Mikhail; Shipova, Ekaterina; Cheng, Rongzhu; Ortwerth, Beryl J.

    2008-01-01

    Previous studies from this laboratory have shown that there are striking similarities between the yellow chromophores, fluorophores and modified amino acids released by proteolytic digestion from calf lens proteins ascorbylated in vitro and their counterparts isolated from aged and cataractous lens proteins. The studies reported in this communication were conducted to further investigate whether ascorbic acid-mediated modification of lens proteins could lead to the formation of lens protein aggregates capable of scattering visible light, similar to the high molecular aggregates found in aged human lenses. Ascorbic acid, but not glucose, fructose, ribose or erythrulose, caused the aggregation of calf lens proteins to proteins ranging from 2.2 × 106 up to 3.0 × 108 Da. This compared to proteins ranging from 1.8 × 106 up to 3.6 × 108 Da for the water-soluble (WS) proteins isolated from aged human lenses. This aggregation was likely due to the glycation of lens crystallins because [U-14C] ascorbate was incorporated into the aggregate fraction and because CNBH3, which reduces the initial Schiff base, prevented any protein aggregation. Reactions of ascorbate with purified crystallin fractions showed little or no aggregation of α-crystallin, significant aggregation of βH-crystallin, but rapid precipitation of purified βL- and γ-crystallin. The aggregation of lens proteins can be prevented by the binding of damaged crystallins to alpha-crystallin due to its chaperone activity. Depending upon the ratios between the components of the incubation mixtures, α-crystallin prevented the precipitation of the purified βL- and γ-crystallin fractions during ascorbylation. The addition of at least 20% of alpha-crystallin by weight into glycation mixtures with βL-, or γ-crystallins completely inhibited protein precipitation, and increased the amount of the high molecular weight aggregates in solution. Static and dynamic light scattering measurements of the supernatants from

  5. Construction aggregates

    USGS Publications Warehouse

    Bolen, W.P.; Tepordei, V.V.

    2001-01-01

    The estimated production during 2000 of construction aggregates, crushed stone, and construction sand and gravel increased by about 2.6% to 2.7 Gt (3 billion st), compared with 1999. The expansion that started in 1992 continued with record production levels for the ninth consecutive year. By commodity, construction sand and gravel production increased by 4.5% to 1.16 Gt (1.28 billion st), while crushed stone production increased by 1.3% to 1.56 Gt (1.72 billion st).

  6. Production of lightweight aggregates from mining residues, heavy metal sludge, and incinerator fly ash.

    PubMed

    Huang, Su-Chen; Chang, Fang-Chih; Lo, Shang-Lien; Lee, Ming-Yu; Wang, Chu-Fang; Lin, Jyh-Dong

    2007-06-01

    In this study, artificial lightweight aggregate (LWA) manufactured from recycled resources was investigated. Residues from mining, fly ash from an incinerator and heavy metal sludge from an electronic waste water plant were mixed into raw aggregate pellets and fed into a tunnel kiln to be sintered and finally cooled rapidly. Various feeding and sintering temperatures were employed to examine their impact on the extent of vitrification on the aggregate surface. Microstructural analysis and toxicity characteristic leaching procedure (TCLP) were also performed. The results show that the optimum condition of LWA fabrication is sintering at 1150 degrees C for 15 min with raw aggregate pellets fed at 750 degrees C. The rapidly vitrified surface envelops the gas produced with the increase in internal temperature and cooling by spraying water prevents the aggregates from binding together, thus forming LWA with specific gravity of 0.6. LWA produced by sintering in tunnel kiln shows good vitrified surface, low water absorption rate below 5%, and low cylindrical compressive strength of 4.3 MPa. In addition, only trace amounts of heavy metals were detected, making the LWA non-hazardous for construction use. PMID:17118542

  7. FITPULS: a code for obtaining analytic fits to aggregate fission-product decay-energy spectra. [In FORTRAN

    SciTech Connect

    LaBauve, R.J.; George, D.C.; England, T.R.

    1980-03-01

    The operation and input to the FITPULS code, recently updated to utilize interactive graphics, are described. The code is designed to retrieve data from a library containing aggregate fine-group spectra (150 energy groups) from fission products, collapse the data to few groups (up to 25), and fit the resulting spectra along the cooling time axis with a linear combination of exponential functions. Also given in this report are useful results for aggregate gamma and beta spectra from the decay of fission products released from /sup 235/U irradiated with a pulse (10/sup -4/ s irradiation time) of thermal neutrons. These fits are given in 22 energy groups that are the first 22 groups of the LASL 25-group decay-energy group structure, and the data are expressed both as MeV per fission second and particles per fission second; these pulse functions are readily folded into finite fission histories. 65 figures, 11 tables.

  8. Labor analytics software can help control labor costs.

    PubMed

    Murray, Lawrence R

    2002-07-01

    One of the largest costs in healthcare organizations is labor. As volume of activity fluctuates, the labor supply needs to be adjusted appropriately. Having an appropriate quantity and skill mix of full- and part-time employees affects labor costs per hour and labor efficiency, two labor-cost control points that department managers need to monitor to make effective hiring decisions. Managers can use software applications for operating budgets, productivity monitoring, position control, and staffing/scheduling to manage labor expenses. Knowing the type of information each of these cost-control tools provides is critical to making effective decisions related to labor expenses. Because of their unique expertise, healthcare financial managers can serve as a resource to help the organization's department managers manage labor costs.

  9. The regulation of work activity and the new labor and production contexts.

    PubMed

    Silva, Elaine Cristina; Bento, Paulo Eduardo Gomes

    2012-01-01

    In recent decades, there has been a rise in the use o lean production model techniques. Through this approach, companies become more flexible, a fact that increases the interest in studies regarding the introduction of this model in businesses and its impacts on working conditions. Important observations concerning ergonomics, such as the theme of work activity regulation, have been highlighted in such studies. This article aims to discuss strategies and regulations adopted by the workers on assembly lines that are considered flexible. The article presents the results of a study in a company that adopts some lean production techniques. The study was analyzed using the activity analysis as one of the premises of the Ergonomic Work Analysis (EWA). Many aspects of the traditional assembly line remain present in the scenario that was studied, however a new language was employed and aspects in the nature of regulations demonstrate that the relation with lean production techniques influence the operators' operational modes.

  10. Construction aggregates

    USGS Publications Warehouse

    Tepordei, V.V.

    1996-01-01

    Part of the Annual Commodities Review 1995. Production of construction aggregates such as crushed stone and construction sand and gravel showed a marginal increase in 1995. Most of the 1995 increases were due to funding for highway construction work. The major areas of concern to the industry included issues relating to wetlands classification and the classification of crystalline silica as a probable human carcinogen. Despite this, an increase in demand is anticipated for 1996.

  11. Construction aggregates

    USGS Publications Warehouse

    Tepordei, V.V.

    1993-01-01

    Part of a special section on the market performance of industrial minerals in 1992. Production of construction aggregates increased by 4.6 percent in 1992. This increase was due, in part, to the increased funding for transportation and infrastructure projects. The U.S. produced about 1.05 Gt of crushed stone and an estimated 734 Mt of construction sand and gravel in 1992. Demand is expected to increase by about 5 percent in 1993.

  12. A comparative study on carbon footprint of rice production between household and aggregated farms from Jiangxi, China.

    PubMed

    Yan, Ming; Luo, Ting; Bian, Rongjun; Cheng, Kun; Pan, Genxing; Rees, Robert

    2015-06-01

    Quantifying the carbon footprint (CF) for crop production can help identify key options to mitigate greenhouse gas (GHG) emissions in agriculture. In the present study, both household and aggregated farm scales were surveyed to obtain the data of rice production and farming management practices in a typical rice cultivation area of Northern Jiangxi, China. The CFs of the different rice systems including early rice, late rice, and single rice under household and aggregated farm scale were calculated. In general, early rice had the lower CF in terms of land use and grain production being 4.54 ± 0.44 t CO2-eq./ha and 0.62 ± 0.1 t CO2-eq./t grain than single rice (6.84 ± 0.79 t CO2-eq./ha and 0.80 ± 0.13 t CO2-eq./t grain) and late rice (8.72 ± 0.54 t CO2-eq./ha and 1.1 ± 0.17 t CO2-eq./t grain). The emissions from nitrogen fertilizer use accounted for 33 % of the total CF on average and the direct CH4 emissions for 57 %. The results indicated that the CF of double rice cropping under aggregated farm being 0.86 ± 0.11 t CO2-eq./t grain was lower by 25 % than that being 1.14 ± 0.25 t CO2-eq./t grain under household farm, mainly due to high nitrogen use efficiency and low methane emissions. Therefore, developing the aggregated farm scale with efficient use of agro-chemicals and farming operation for greater profitability could offer a strategy for reducing GHG emissions in China's agriculture.

  13. A comparative study on carbon footprint of rice production between household and aggregated farms from Jiangxi, China.

    PubMed

    Yan, Ming; Luo, Ting; Bian, Rongjun; Cheng, Kun; Pan, Genxing; Rees, Robert

    2015-06-01

    Quantifying the carbon footprint (CF) for crop production can help identify key options to mitigate greenhouse gas (GHG) emissions in agriculture. In the present study, both household and aggregated farm scales were surveyed to obtain the data of rice production and farming management practices in a typical rice cultivation area of Northern Jiangxi, China. The CFs of the different rice systems including early rice, late rice, and single rice under household and aggregated farm scale were calculated. In general, early rice had the lower CF in terms of land use and grain production being 4.54 ± 0.44 t CO2-eq./ha and 0.62 ± 0.1 t CO2-eq./t grain than single rice (6.84 ± 0.79 t CO2-eq./ha and 0.80 ± 0.13 t CO2-eq./t grain) and late rice (8.72 ± 0.54 t CO2-eq./ha and 1.1 ± 0.17 t CO2-eq./t grain). The emissions from nitrogen fertilizer use accounted for 33 % of the total CF on average and the direct CH4 emissions for 57 %. The results indicated that the CF of double rice cropping under aggregated farm being 0.86 ± 0.11 t CO2-eq./t grain was lower by 25 % than that being 1.14 ± 0.25 t CO2-eq./t grain under household farm, mainly due to high nitrogen use efficiency and low methane emissions. Therefore, developing the aggregated farm scale with efficient use of agro-chemicals and farming operation for greater profitability could offer a strategy for reducing GHG emissions in China's agriculture. PMID:25947895

  14. Estimated economic benefits during the 'decade of vaccines' include treatment savings, gains in labor productivity.

    PubMed

    Stack, Meghan L; Ozawa, Sachiko; Bishai, David M; Mirelman, Andrew; Tam, Yvonne; Niessen, Louis; Walker, Damian G; Levine, Orin S

    2011-06-01

    In 2010 the Bill & Melinda Gates Foundation announced a $10 billion commitment over the next ten years to increase access to childhood vaccines in the world's poorest countries. The effort was labeled the "Decade of Vaccines." This study estimates both the short- and long-term economic benefits from the introduction and increased use of six vaccines in seventy-two of the world's poorest countries from 2011 to 2020. Increased rates of vaccination against pneumococcal and Haemophilus influenzae type b pneumonia and meningitis, rotavirus, pertussis, measles, and malaria over the next ten years would save 6.4 million lives and avert 426 million cases of illness, $6.2 billion in treatment costs, and $145 billion in productivity losses. Monetary estimates based on this type of analysis can be used to determine the return on investment in immunization from both the international community and local governments, and they should be considered in policy making. PMID:21653952

  15. Labor Exchange Skills Project. Final Report.

    ERIC Educational Resources Information Center

    Dietrich, Eleanor; Hendrickson-Larson, Joanna; Hoppe, Ruth; Paige, Bruce; Rosenow, Steve

    The Labor Exchange Skills Project, which was conducted under the sponsorship and direction of the U.S. Department of Labor, Employment and Training Administration, was designed to develop a labor exchange skills database (ETA) that would improve the usability of many Department of Labor applications and products developed by other public and…

  16. Production efficiencies of U.S. electric generation plants: Effects of data aggregation and greenhouse gas and renewable energy policy

    NASA Astrophysics Data System (ADS)

    Lynes, Melissa Kate

    Over the last few decades there has been a shift in electricity production in the U.S. Renewable energy sources are becoming more widely used. In addition, electric generation plants that use coal inputs are more heavily regulated than a couple decades ago. This shift in electricity production was brought on by changes in federal policy -- a desire for electricity produced in the U.S. which led to policies being adopted that encourage the use of renewable energy. The change in production practices due to policies may have led to changes in the productivity of electric generation plants. Multiple studies have examined the most efficient electric generation plants using the data envelopment analysis (DEA) approach. This study builds on past research to answer three questions: 1) Does the level of aggregation of fuel input variables affect the plant efficiency scores and how does the efficiency of renewable energy input compare to nonrenewable energy inputs; 2) Are policies geared toward directly or indirectly reducing greenhouse gas emissions affecting the production efficiencies of greenhouse gas emitting electric generation plants; and 3) Do renewable energy policies and the use of intermittent energy sources (i.e. wind and solar) affect the productivity growth of electric generation plants. All three analysis, presented in three essays, use U.S. plant level data obtained from the Energy Information Administration to answer these questions. The first two essays use DEA to determine the pure technical, overall technical, and scale efficiencies of electric generation plants. The third essay uses DEA within the Malmquist index to assess the change in productivity over time. Results indicate that the level of aggregation does matter particularly for scale efficiency. This implies that valuable information is likely lost when fuel inputs are aggregated together. Policies directly focused on reducing greenhouse gas emissions may improve the production efficiencies of

  17. Beclin-1 deficiency in the murine ovary results in the reduction of progesterone production to promote preterm labor

    PubMed Central

    Gawriluk, Thomas R.; Ko, CheMyong; Hong, Xiaoman; Christenson, Lane K.; Rucker, Edmund B.

    2014-01-01

    Autophagy is an important cellular process that serves as a companion pathway to the ubiquitin-proteasome system to degrade long-lived proteins and organelles to maintain cell homeostasis. Although initially characterized in yeast, autophagy is being realized as an important regulator of development and disease in mammals. Beclin1 (Becn1) is a putative tumor suppressor gene that has been shown to undergo a loss of heterozygosity in 40–75% of human breast, ovarian, and prostate cancers. Because Becn1 is a key regulator of autophagy, we sought to investigate its role in female reproduction by using a conditional knockout approach in mice. We find that pregnant females lacking Becn1 in the ovarian granulosa cell population have a defect in progesterone production and a subsequent preterm labor phenotype. Luteal cells in this model exhibit defective autophagy and a failure to accumulate lipid droplets needed for steroidogenesis. Collectively, we show that Becn1 provides essential functions in the ovary that are essential for mammalian reproduction. PMID:25246579

  18. Beclin-1 deficiency in the murine ovary results in the reduction of progesterone production to promote preterm labor.

    PubMed

    Gawriluk, Thomas R; Ko, CheMyong; Hong, Xiaoman; Christenson, Lane K; Rucker, Edmund B

    2014-10-01

    Autophagy is an important cellular process that serves as a companion pathway to the ubiquitin-proteasome system to degrade long-lived proteins and organelles to maintain cell homeostasis. Although initially characterized in yeast, autophagy is being realized as an important regulator of development and disease in mammals. Beclin1 (Becn1) is a putative tumor suppressor gene that has been shown to undergo a loss of heterozygosity in 40-75% of human breast, ovarian, and prostate cancers. Because Becn1 is a key regulator of autophagy, we sought to investigate its role in female reproduction by using a conditional knockout approach in mice. We find that pregnant females lacking Becn1 in the ovarian granulosa cell population have a defect in progesterone production and a subsequent preterm labor phenotype. Luteal cells in this model exhibit defective autophagy and a failure to accumulate lipid droplets needed for steroidogenesis. Collectively, we show that Becn1 provides essential functions in the ovary that are essential for mammalian reproduction.

  19. The effect of the menstrual cycle and of decompression stress on arachidonic acid-induced platelet aggregation and on intrinsic platelet thromboxane production in women compared with men.

    PubMed

    Markham, S M; Dubin, N H; Rock, J A

    1991-12-01

    Menstrual cycle variations in platelet aggregation and thromboxane production in association with sex steroids have been reported. External stimuli such as decompression sickness have been associated with clotting activity changes, specifically, increased platelet aggregation. Differences in response of platelets from women and men, when subjected to such a stress, have been observed. This study evaluated the ability of washed platelets from women in the proliferative and secretory phases of the menstrual cycle to aggregate in response to arachidonic acid and the aggregation difference between washed platelets from women and men in response to decompression stress and arachidonic acid. Additionally, platelet thromboxane production differences between the assessed platelet populations were compared. Our results indicate no difference in platelet aggregability between phases of the menstrual cycle. A significant aggregation difference between platelets from women and men was noted. Platelets from women were more sensitive to arachidonic acid aggregation. These differences were not affected by decompression stress. No difference in thromboxane B2 production was noted between the platelet populations evaluated.

  20. Valorisation of different types of boron-containing wastes for the production of lightweight aggregates.

    PubMed

    Kavas, T; Christogerou, A; Pontikes, Y; Angelopoulos, G N

    2011-01-30

    Four boron-containing wastes (BW), named as Sieve (SBW), Dewatering (DBW), Thickener (TBW) and Mixture (MBW) waste, from Kirka Boron plant in west Turkey were investigated for the formation of artificial lightweight aggregates (LWA). The characterisation involved chemical, mineralogical and thermal analyses as well as testing of their bloating behaviour by means of heating microscopy. It was found that SBW and DBW present bloating behaviour whereas TBW and MBW do not. Following the above results two mixtures M1 and M2 were prepared with (in wt.%): 20 clay mixture, 40 SBW, 40 DBW and 20 clay mixture, 35 SBW, 35 DBW, 10 quartz sand, respectively. Two different firing modes were applied: (a) from room temperature till 760 °C and (b) abrupt heating at 760 °C. The obtained bulk density for M1 and M2 pellets is 1.2g/cm(3) and 0.9 g/cm(3), respectively. The analysis of microstructure with electron microscopy revealed a glassy phase matrix and an extended formation of both interconnected and isolated, closed pores. The results indicate that SBW and DBW boron-containing wastes combined with a clay mixture and quartz sand can be valorised for the manufacturing of lightweight aggregates. PMID:21075514

  1. Symbiotic Cell Differentiation and Cooperative Growth in Multicellular Aggregates

    PubMed Central

    Yamagishi, Jumpei F; Saito, Nen; Kaneko, Kunihiko

    2016-01-01

    As cells grow and divide under a given environment, they become crowded and resources are limited, as seen in bacterial biofilms and multicellular aggregates. These cells often show strong interactions through exchanging chemicals, as evident in quorum sensing, to achieve mutualism and division of labor. Here, to achieve stable division of labor, three characteristics are required. First, isogenous cells differentiate into several types. Second, this aggregate of distinct cell types shows better growth than that of isolated cells without interaction and differentiation, by achieving division of labor. Third, this cell aggregate is robust with respect to the number distribution of differentiated cell types. Indeed, theoretical studies have thus far considered how such cooperation is achieved when the ability of cell differentiation is presumed. Here, we address how cells acquire the ability of cell differentiation and division of labor simultaneously, which is also connected with the robustness of a cell society. For this purpose, we developed a dynamical-systems model of cells consisting of chemical components with intracellular catalytic reaction dynamics. The reactions convert external nutrients into internal components for cellular growth, and the divided cells interact through chemical diffusion. We found that cells sharing an identical catalytic network spontaneously differentiate via induction from cell-cell interactions, and then achieve division of labor, enabling a higher growth rate than that in the unicellular case. This symbiotic differentiation emerged for a class of reaction networks under the condition of nutrient limitation and strong cell-cell interactions. Then, robustness in the cell type distribution was achieved, while instability of collective growth could emerge even among the cooperative cells when the internal reserves of products were dominant. The present mechanism is simple and general as a natural consequence of interacting cells with

  2. Dissociation and Re-Aggregation of Multicell-Ensheathed Fragments Responsible for Rapid Production of Massive Clumps of Leptothrix Sheaths.

    PubMed

    Kunoh, Tatsuki; Nagaoka, Noriyuki; McFarlane, Ian R; Tamura, Katsunori; El-Naggar, Mohamed Y; Kunoh, Hitoshi; Takada, Jun

    2016-01-01

    Species of the Fe/Mn-oxidizing bacteria Leptothrix produce tremendous amounts of microtubular, Fe/Mn-encrusted sheaths within a few days in outwells of groundwater that can rapidly clog water systems. To understand this mode of rapid sheath production and define the timescales involved, behaviors of sheath-forming Leptothrix sp. strain OUMS1 were examined using time-lapse video at the initial stage of sheath formation. OUMS1 formed clumps of tangled sheaths. Electron microscopy confirmed the presence of a thin layer of bacterial exopolymer fibrils around catenulate cells (corresponding to the immature sheath). In time-lapse videos, numerous sheath filaments that extended from the periphery of sheath clumps repeatedly fragmented at the apex of the same fragment, the fragments then aggregated and again elongated, eventually forming a large sheath clump comprising tangled sheaths within two days. In this study, we found that fast microscopic fragmentation, dissociation, re-aggregation and re-elongation events are the basis of the rapid, massive production of Leptothrix sheaths typically observed at macroscopic scales. PMID:27490579

  3. Utilization of Illinois slags for the production of ultra-lightweight aggregates. Technical report, December 1, 1992--February 28, 1993

    SciTech Connect

    Choudhry, V.; Zimmerle, T.; Banerjee, D.D.

    1993-05-01

    The objective of this program is to demonstrate that solid residues (slag) from the gasification of Illinois coals can be utilized to manufacture ultra-lightweight aggregates (ULWA). Conventional ULWAs are made by pyroprocessing perlite ores and have unit weights in the range of 3--15 lb/ft{sup 3}. In a previous project, Praxis Engineers demonstrated at the pilot scale that lightweight aggregates with unit weights of 40--55 lb/ ft{sup 3} can be produced from Illinois coal slags, which is suitable for making lightweight cement concrete and precast blocks. These tests also indicated that a product with a unit weight of less than 25 lb/ft{sup 3} could be produced from slag. This project is aimed at testing the potential for producing ULWA from Illinois coal slags. Target applications include loose fill insulation, insulating concrete, lightweight precast products such as concrete blocks and rooftiles, and filtration media. Laboratory- and pilot-scale testing is being conducted in Phase I to identify operating conditions for the expansion of Illinois slags to produce ULWA. Following this, a large batch of expanded slag will be produced, for evaluation in various applications in Phase II.

  4. Dissociation and Re-Aggregation of Multicell-Ensheathed Fragments Responsible for Rapid Production of Massive Clumps of Leptothrix Sheaths

    PubMed Central

    Kunoh, Tatsuki; Nagaoka, Noriyuki; McFarlane, Ian R.; Tamura, Katsunori; El-Naggar, Mohamed Y.; Kunoh, Hitoshi; Takada, Jun

    2016-01-01

    Species of the Fe/Mn-oxidizing bacteria Leptothrix produce tremendous amounts of microtubular, Fe/Mn-encrusted sheaths within a few days in outwells of groundwater that can rapidly clog water systems. To understand this mode of rapid sheath production and define the timescales involved, behaviors of sheath-forming Leptothrix sp. strain OUMS1 were examined using time-lapse video at the initial stage of sheath formation. OUMS1 formed clumps of tangled sheaths. Electron microscopy confirmed the presence of a thin layer of bacterial exopolymer fibrils around catenulate cells (corresponding to the immature sheath). In time-lapse videos, numerous sheath filaments that extended from the periphery of sheath clumps repeatedly fragmented at the apex of the same fragment, the fragments then aggregated and again elongated, eventually forming a large sheath clump comprising tangled sheaths within two days. In this study, we found that fast microscopic fragmentation, dissociation, re-aggregation and re-elongation events are the basis of the rapid, massive production of Leptothrix sheaths typically observed at macroscopic scales. PMID:27490579

  5. An aggregate analysis of personal care products in the environment: Identifying the distribution of environmentally-relevant concentrations.

    PubMed

    Hopkins, Zachary R; Blaney, Lee

    2016-01-01

    Over the past 3-4 decades, per capita consumption of personal care products (PCPs) has steadily risen, resulting in increased discharge of the active and inactive ingredients present in these products into wastewater collection systems. PCPs comprise a long list of compounds employed in toothpaste, sunscreen, lotions, soaps, body washes, and insect repellants, among others. While comprehensive toxicological studies are not yet available, an increasing body of literature has shown that PCPs of all classes can impact aquatic wildlife, bacteria, and/or mammalian cells at low concentrations. Ongoing research efforts have identified PCPs in a variety of environmental compartments, including raw wastewater, wastewater effluent, surface water, wastewater solids, sediment, groundwater, and drinking water. Here, an aggregate analysis of over 5000 reported detections was conducted to better understand the distribution of environmentally-relevant PCP concentrations in, and between, these compartments. The distributions were used to identify whether aggregated environmentally-relevant concentration ranges intersected with available toxicity data. For raw wastewater, wastewater effluent, and surface water, a clear overlap was present between the 25th-75th percentiles and identified toxicity levels. This analysis suggests that improved wastewater treatment of antimicrobials, UV filters, and polycyclic musks is required to prevent negative impacts on aquatic species. PMID:27128715

  6. Lipid Rafts: Linking Alzheimer's Amyloid-β Production, Aggregation, and Toxicity at Neuronal Membranes

    PubMed Central

    Rushworth, Jo V.; Hooper, Nigel M.

    2011-01-01

    Lipid rafts are membrane microdomains, enriched in cholesterol and sphingolipids, into which specific subsets of proteins and lipids partition, creating cell-signalling platforms that are vital for neuronal functions. Lipid rafts play at least three crucial roles in Alzheimer's Disease (AD), namely, in promoting the generation of the amyloid-β (Aβ) peptide, facilitating its aggregation upon neuronal membranes to form toxic oligomers and hosting specific neuronal receptors through which the AD-related neurotoxicity and memory impairments of the Aβ oligomers are transduced. Recent evidence suggests that Aβ oligomers may exert their deleterious effects through binding to, and causing the aberrant clustering of, lipid raft proteins including the cellular prion protein and glutamate receptors. The formation of these pathogenic lipid raft-based platforms may be critical for the toxic signalling mechanisms that underlie synaptic dysfunction and neuropathology in AD. PMID:21234417

  7. Abiotic factors in colony formation: effects of nutrition and light on extracellular polysaccharide production and cell aggregates of Microcystis aeruginosa

    NASA Astrophysics Data System (ADS)

    Yang, Zhen; Kong, Fanxiang

    2013-07-01

    Colony morphology is important for Microcystis to sustain a competitive advantage in eutrophic lakes. The mechanism of colony formation in Microcystis is currently unclear. Extracellular polysaccharide (EPS) has been reported to play an important role in cell aggregate formation of some phytoplankton. Microcystis aeruginosa was cultivated under varied abiotic conditions, including different nutrient, light, and temperature conditions, to investigate their effects on EPS production and morphological change. The results show that nutrient concentration and light intensity have great effects on EPS productionin M. aeruginosa. There was a considerable increase in EPS production after M. aeruginosa was cultivated in adjusted culture conditions similar to those present in the field (28.9 mg C/L, 1.98 mg N/L, 0.65 mg P/L, light intensity: 100 μmol/(m2 · s)). These results indicate that abiotic factors might be one of the triggers for colony formation in Microcystis.

  8. The Japanese Domestic Labor Debate.

    ERIC Educational Resources Information Center

    Ueno, Chizuko

    The changing role of Japanese women can be seen in the stages of a domestic labor debate which occurred at three different times in the past 30 years. The first debate began with Ayako Ishigaki's (1955) insistence that women should have a job outside the home. Wartime production helped break down traditional divisions of labor by encouraging women…

  9. Aggregate exposure approaches for parabens in personal care products: a case assessment for children between 0 and 3 years old

    PubMed Central

    Gosens, Ilse; Delmaar, Christiaan J E; ter Burg, Wouter; de Heer, Cees; Schuur, A Gerlienke

    2014-01-01

    In the risk assessment of chemical substances, aggregation of exposure to a substance from different sources via different pathways is not common practice. Focusing the exposure assessment on a substance from a single source can lead to a significant underestimation of the risk. To gain more insight on how to perform an aggregate exposure assessment, we applied a deterministic (tier 1) and a person-oriented probabilistic approach (tier 2) for exposure to the four most common parabens through personal care products in children between 0 and 3 years old. Following a deterministic approach, a worst-case exposure estimate is calculated for methyl-, ethyl-, propyl- and butylparaben. As an illustration for risk assessment, Margins of Exposure (MoE) are calculated. These are 991 and 4966 for methyl- and ethylparaben, and 8 and 10 for propyl- and butylparaben, respectively. In tier 2, more detailed information on product use has been obtained from a small survey on product use of consumers. A probabilistic exposure assessment is performed to estimate the variability and uncertainty of exposure in a population. Results show that the internal exposure for each paraben is below the level determined in tier 1. However, for propyl- and butylparaben, the percentile of the population with an exposure probability above the assumed “safe” MoE of 100, is 13% and 7%, respectively. In conclusion, a tier 1 approach can be performed using simple equations and default point estimates, and serves as a starting point for exposure and risk assessment. If refinement is warranted, the more data demanding person-oriented probabilistic approach should be used. This probabilistic approach results in a more realistic exposure estimate, including the uncertainty, and allows determining the main drivers of exposure. Furthermore, it allows to estimate the percentage of the population for which the exposure is likely to be above a specific value. PMID:23801276

  10. Aggregate Fission-Product Decay Data Based on ENDF/B-IV and -V.

    1982-10-12

    Version 02 The ENDF/B-IV fission-product files contain neutron cross sections, decay constants, decay energies, and other decay data for 824 important fission products. They also contain fission yields for these fission products produced by one or more fission-neutron energies (14 MeV, fast, and thermal fission). Also, spectral data exist for the most important decay-heat contributors among the 824 nuclides. Because the spectra are based on fission pulses, the libraries have a general utility. The exponentialmore » fits, for example, can be folded into any power (fission) history that can be described analytically or by a histogram representation. The effects of neutron absorption are also treated and approximately accounted for in the methodology.« less

  11. Grid Integration of Aggregated Demand Response, Part 2: Modeling Demand Response in a Production Cost Model

    SciTech Connect

    Hummon, Marissa; Palchak, David; Denholm, Paul; Jorgenson, Jennie; Olsen, Daniel J.; Kiliccote, Sila; Matson, Nance; Sohn, Michael; Rose, Cody; Dudley, Junqiao; Goli, Sasank; Ma, Ookie

    2013-12-01

    This report is one of a series stemming from the U.S. Department of Energy (DOE) Demand Response and Energy Storage Integration Study. This study is a multi-national-laboratory effort to assess the potential value of demand response (DR) and energy storage to electricity systems with different penetration levels of variable renewable resources and to improve our understanding of associatedmarkets and institutions. This report implements DR resources in the commercial production cost model PLEXOS.

  12. Black tattoo inks induce reactive oxygen species production correlating with aggregation of pigment nanoparticles and product brand but not with the polycyclic aromatic hydrocarbon content.

    PubMed

    Høgsberg, Trine; Jacobsen, Nicklas Raun; Clausen, Per Axel; Serup, Jørgen

    2013-07-01

    Black tattoo inks are composed of carbon nanoparticles, additives and water and may contain polycyclic aromatic hydrocarbons (PAHs). We aimed to clarify whether reactive oxygen species (ROS) induced by black inks in vitro is related to pigment chemistry, physico-chemical properties of the ink particles and the content of chemical additives and contaminants including PAHs. The study included nine brands of tattoo inks of six colours each (black, red, yellow, blue, green and white) and two additional black inks of different brands (n = 56). The ROS formation potential was determined by the dichlorofluorescein (DCFH) assay. A semiquantitative method was developed for screening extractable organic compounds in tattoo ink based on gas chromatography-mass spectrometry (GC-MS) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS). Two black inks produced high amounts of ROS. Peroxyl radicals accounted for up to 72% of the free radicals generated, whereas hydroxyl radicals and H₂O₂ accounted for <14% and 16%, respectively. The same two inks aggregated strongly in water in contrast to the other black inks. They did not exhibit any shared pattern in PAHs and other organic substances. Aggregation was exclusively shared by all ink colours belonging to the same two brands. Ten of 11 black inks had PAH concentrations exceeding the European Council's recommended level, and all 11 exceeded the recommended level for benzo(a)pyrene. It is a new finding that aggregation of tattoo pigment particles correlates with ROS production and brand, independently of chemical composition including PAHs. ROS is hypothesized to be implicated in minor clinical symptoms.

  13. 9 CFR 590.970 - Charges for storage, cartage, and labor with respect to products imported contrary to the Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Charges for storage, cartage, and... Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION INSPECTION OF EGGS AND EGG PRODUCTS (EGG PRODUCTS INSPECTION ACT) Imports § 590.970 Charges for storage,...

  14. 9 CFR 590.970 - Charges for storage, cartage, and labor with respect to products imported contrary to the Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Charges for storage, cartage, and... Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION INSPECTION OF EGGS AND EGG PRODUCTS (EGG PRODUCTS INSPECTION ACT) Imports § 590.970 Charges for storage,...

  15. Sewage sludge sugarcane trash based compost and synthetic aggregates as peat substitutes in containerized media for crop production.

    PubMed

    Jayasinghe, G Y; Tokashiki, Yoshihiro; Arachchi, I D Liyana; Arakaki, Mika

    2010-02-15

    Effect of partial substitution of peat in growth media by sewage sludge sugarcane trash based compost (SSC) and synthetic aggregates (SA) on the physical and chemical characteristics of the growth media and on the growth and nutrition of lettuce (Lactuca sativa L.) grown in the substituted media was investigated under this study. SSC was produced from sugarcane trash and sewage sludge. Unconventional SA were produced by low productive acidic red soil with paper waste and starch waste. The treatments assayed were: SSC (40%)+Peat (60%), SA (40%)+Peat (60%), SSC (60%)+SA (40%), SSC (40%)+SA (20%)+Peat (40%) and SSC (40%)+SA (40%)+Peat (20%). Peat only was used as the control. The physical and chemical properties of all growing media were analyzed. SSC-SA based substrates showed adequate physical and chemical properties compared to peat for their use as growing media in horticulture. In relation to the plant growth in peat control, plants grown in the SSC-SA based substrates reached better growth and nutrition. The concentration of trace elements in plant tissues was far lower than the ranges considered phytotoxic for plants. Utilization of SSC and SA can be considered as an alternative media component to substitute the widely using expensive peat in horticulture.

  16. Migrant labor in agriculture: an international comparison.

    PubMed

    Martin, P L

    1985-01-01

    The May 1984 Conference on Migrant Labor in Agriculture at the University of California-Davis discussed papers by 22 farm labor experts from 12 nations. Each industrial nation utilizes a different set of public and private policies to supply workers for labor-intensive agriculture, but none is entirely satisfactory. Labor-intensive agriculture is becoming more dependent on workers who are shut out of labor markets. Some countries have simply accepted foreign workers in agriculture, while others have adopted policies to integrate farm and nonfarm labor markets. Polices to reduce agriculture's reliance on workers-without-options include restructuring employment practices to employ fewer seasonal workers for longer periods, mechanizing production, and importing fruits and vegetables from nearby developing countries. This article explains the salient features of labor-intensive agriculture, the various polices for obtaining seasonal farmworkers, and options to reduce farming's dependence on migrant labor.

  17. Quantitative risk assessment of the aggregate dermal exposure to the sensitizing fragrance geraniol in personal care products and household cleaning agents.

    PubMed

    Nijkamp, M M; Bokkers, B G H; Bakker, M I; Ezendam, J; Delmaar, J E

    2015-10-01

    A quantitative risk assessment was performed to establish if consumers are at risk for being dermally sensitized by the fragrance geraniol. Aggregate dermal exposure to geraniol was estimated using the Probabilistic Aggregate Consumer Exposure Model, containing data on the use of personal care products and household cleaning agents. Consumer exposure to geraniol via personal care products appeared to be higher than via household cleaning agents. The hands were the body parts receiving the highest exposure to geraniol. Dermal sensitization studies were assessed to derive the point of departure needed for the estimation of the Acceptable Exposure Level (AEL). Two concentrations were derived, one based on human studies and the other from dose-response analysis of the available murine local lymph node assay data. The aggregate dermal exposure assessment resulted in body part specific median exposures up to 0.041 μg/cm(2) (highest exposure 102 μg/cm(2)) for hands. Comparing the exposure to the lowest AEL (55 μg/cm(2)), shows that a range of 0.02-0.86% of the population may have an aggregated exposure which exceeds the AEL. Furthermore, it is demonstrated that personal care products contribute more to the consumer's geraniol exposure compared to household cleaning agents. PMID:26107291

  18. Quantitative risk assessment of the aggregate dermal exposure to the sensitizing fragrance geraniol in personal care products and household cleaning agents.

    PubMed

    Nijkamp, M M; Bokkers, B G H; Bakker, M I; Ezendam, J; Delmaar, J E

    2015-10-01

    A quantitative risk assessment was performed to establish if consumers are at risk for being dermally sensitized by the fragrance geraniol. Aggregate dermal exposure to geraniol was estimated using the Probabilistic Aggregate Consumer Exposure Model, containing data on the use of personal care products and household cleaning agents. Consumer exposure to geraniol via personal care products appeared to be higher than via household cleaning agents. The hands were the body parts receiving the highest exposure to geraniol. Dermal sensitization studies were assessed to derive the point of departure needed for the estimation of the Acceptable Exposure Level (AEL). Two concentrations were derived, one based on human studies and the other from dose-response analysis of the available murine local lymph node assay data. The aggregate dermal exposure assessment resulted in body part specific median exposures up to 0.041 μg/cm(2) (highest exposure 102 μg/cm(2)) for hands. Comparing the exposure to the lowest AEL (55 μg/cm(2)), shows that a range of 0.02-0.86% of the population may have an aggregated exposure which exceeds the AEL. Furthermore, it is demonstrated that personal care products contribute more to the consumer's geraniol exposure compared to household cleaning agents.

  19. Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with Itself and the CHO Cells That Synthesize It

    PubMed Central

    Kim, Dong-Ki; Choi, Hosoon; Nishida, Hidetaka; Oh, Joo Youn; Gregory, Carl; Lee, Ryang Hwa; Yu, Ji Min; Watanabe, Jun; An, Su Yeon; Bartosh, Thomas J.; Prockop, Darwin J.

    2016-01-01

    TNF-α stimulated gene/protein 6 (TNFAIP6/TSG-6) is a multifunctional protein that has a number of potential therapeutic applications. Experiments and clinical trials with TSG-6, however, have been limited by the technical difficulties of producing the recombinant protein. We prepared stable clones of CHO cells that expressed recombinant human TSG-6 (rhTSG-6) as a secreted glycoprotein. Paradoxically, both cell number and protein production decreased dramatically when the clones were expanded. The decreases occurred because the protein aggregated the synthesizing CHO cells by binding to the brush border of hyaluronan that is found around many cultured cells. In addition, the rhTSG-6 readily self-aggregated. To address these problems, we added to the medium an inhibitor of hyaluronan synthesis and heparin to compete with the binding of TSG-6 to hyaluronan. Also, we optimized the composition of the culture medium, and transferred the CHO cells from a spinner culture system to a bioreactor that controlled pH and thereby decreased pH-dependent binding properties of the protein. With these and other improvements in the culture conditions, we obtained 57.0 mg ± 9.16 S.D. of rhTSG-6 in 5 or 6 liter of medium. The rhTSG-6 accounted for 18.0% ± 3.76 S.D. of the total protein in the medium. We then purified the protein with a Ni-chelate column that bound the His tag engineered into the C-terminus of the protein followed by an anion exchange column. The yield of the purified monomeric rhTSG-6 was 4.1 mg to 5.6 mg per liter of culture medium. After intravenous injection into mice, the protein had a longer plasma half-life than commercially available rhTSG-6 isolated from a mammalian cell lysate, apparently because it was recovered as a secreted glycoprotein. The bioactivity of the rhTSG-6 in suppressing inflammation was demonstrated in a murine model. PMID:26793973

  20. Inhibition of whole blood platelet-aggregation by compounds in garlic clove extracts and commercial garlic products.

    PubMed

    Lawson, L D; Ransom, D K; Hughes, B G

    1992-01-15

    The inhibitory effects of adenosine and 16 quantitatively determined organosulfur compounds derived from garlic cloves or commercial garlic preparations on collagen stimulated in vitro platelet aggregation in whole blood were determined. An estimation of the anti-aggregatory activity of several brands of the major types of commercial garlic preparations was determined from the activities of the individual compounds present in each sample. In platelet rich plasma (PRP) most of the anti-aggregatory activity of garlic clove homogenates was due to adenosine; however, in whole blood neither adenosine nor the polar fraction had any effect and all of the anti-aggregatory activity was due to allicin and other thiosulfinates. Allicin was equally active in whole blood and PRP. Among brands there was a several-fold variation in content of the organosulfur compounds and activity for all types of garlic products tested. The best garlic powder tablets were equally as active as clove homogenates whereas steam-distilled oils were 35% as active and oil-macerates (due to low content) only 12% as active. A garlic product aged many months in aqueous alcohol had no activity. For steam-distilled oils, most of the activity was due to diallyl trisulfide. For the oil-macerates, most of the activity was due largely to the vinyl dithiins. Ajoene, an exclusive component of the oil-macerates, had highest specific activity of all the compounds tested but, because of its low concentration, had only 13% of the activity of diallyl trisulfide and 3% of the activity of allicin. Compounds which may be active in vivo are discussed. PMID:1579891

  1. Diel Rhythms in Monochamus (Coleoptera: Cerambycidae): Production of and Response to a Male-Produced Aggregation Pheromone.

    PubMed

    Skabeikis, D D; Teale, S A; Fierke, M K

    2016-08-01

    Recent research has shown that several species in the genus Monochamus, including Monochamus scutellatus scutellatus (Say) and Monochamus notatus (Drury), a close congener, are attracted to an aggregation pheromone, monochamol, but only M. s. scutellatus produces it. Investigations were conducted to determine if there is a diel rhythm in production of monochamol or response to monochamol + host attractants in field trials by M. s. scutellatus and M. notatus to prevent cross attraction with each other. Volatiles were collected from males and females of M. s. scutellatus and M. notatus every 8 h and analyzed by coupled gas chromatography-mass spectrometry. Traps baited with monochamol and the host volatiles α-pinene and ethanol were checked every 8 h in field tests. Only male M. s. scutellatus produced the pheromone, and did so in similar quantities during each 8-h time interval assessed, suggesting there is no diel rhythm in pheromone production. In field tests conducted in early to mid-July, significantly more M. s. scutellatus were captured during morning hours, and significantly more M. notatus were caught during afternoon or early evening hours, suggesting temporal partitioning of flight or in their response to the pheromone lures when both species are present. A temporal switch occurred later in the seasonal flight period (mid-August) when densities of M. s. scutellatus were low; all M. notatus and only one M. s. scutellatus were caught during morning hours. This suggests a temporal separation in mate location behavior when both species are abundant and using the same host to avoid interspecific mating. PMID:27252408

  2. Rockdusting technique cuts labor requirements

    SciTech Connect

    Mason, R.H.

    1983-12-01

    Brownies Creek Collieries has aggressively sought cost reductions while maintaining production quotas. The operation scrutinized costs in a computerized analysis, and found that exact costs could not be determined for rockdusting. Rockdusting costs were buried under mine supply costs and maintenance labor. Mine management had to physically examine rockdusting procedures to determine costs. Mine Manager Dave Roberts and his staff discovered in their personal underground analysis of rockdusting that labor and supplies were being unnecessarily wasted.

  3. Automation of aggregate characterization using laser profiling and digital image analysis

    NASA Astrophysics Data System (ADS)

    Kim, Hyoungkwan

    2002-08-01

    Particle morphological properties such as size, shape, angularity, and texture are key properties that are frequently used to characterize aggregates. The characteristics of aggregates are crucial to the strength, durability, and serviceability of the structure in which they are used. Thus, it is important to select aggregates that have proper characteristics for each specific application. Use of improper aggregate can cause rapid deterioration or even failure of the structure. The current standard aggregate test methods are generally labor-intensive, time-consuming, and subject to human errors. Moreover, important properties of aggregates may not be captured by the standard methods due to a lack of an objective way of quantifying critical aggregate properties. Increased quality expectations of products along with recent technological advances in information technology are motivating new developments to provide fast and accurate aggregate characterization. The resulting information can enable a real time quality control of aggregate production as well as lead to better design and construction methods of portland cement concrete and hot mix asphalt. This dissertation presents a system to measure various morphological characteristics of construction aggregates effectively. Automatic measurement of various particle properties is of great interest because it has the potential to solve such problems in manual measurements as subjectivity, labor intensity, and slow speed. The main efforts of this research are placed on three-dimensional (3D) laser profiling, particle segmentation algorithms, particle measurement algorithms, and generalized particle descriptors. First, true 3D data of aggregate particles obtained by laser profiling are transformed into digital images. Second, a segmentation algorithm and a particle measurement algorithm are developed to separate particles and process each particle data individually with the aid of various kinds of digital image

  4. Reply to Vangala et al.: Complete inhibition of the proteasome reduces new proteasome production by causing Nrf1 aggregation.

    PubMed

    Sha, Zhe; Goldberg, Alfred L

    2016-09-26

    An important adaptation of cells to proteasome inhibition is the induction of new proteasomes via the transcription factor Nrf1 [1,2], which is produced as a precursor bound to the endoplasmic reticulum (ER) through its amino terminus. Nrf1 was reported to require proteolytic processing to enter the nucleus [3]. Increased proteasome production is induced by low concentrations of proteasome inhibitors that reduce proteolysis by <50%. Surprisingly, in earlier studies we found that proteasome induction and Nrf1 processing to its shorter form (which we estimated to be 75 kDa [2]) were suppressed by high concentrations of inhibitors that markedly reduce proteasome activity [4]. This unusual bimodal concentration dependence implied that some proteasome function was necessary for Nrf1 processing. Because we found that Nrf1 processing also required ubiquitin conjugation [2], we previously proposed that Nrf1 processing is catalyzed by partially inhibited proteasomes [2]. However, Vangala et al.[5] present compelling evidence that conversion of the ER-bound Nrf1 to the shorter form, which they describe as 110 kDa, is independent of proteasomes and is not blocked by high concentrations of proteasome inhibitors. Therefore, we investigated the basis for these differing results. Here we report that we and Vangala et al. have studied the same processed form of Nrf1, the actual molecular weight of which appears to be 90-95 kDa. We confirm our earlier finding [2] that high concentrations of proteasome inhibitors suppress proteasome induction and accumulation of processed Nrf1 in soluble lysates. However, we now show that the inhibitors do so not by blocking Nrf1 processing, but instead by causing the processed Nrf1 to aggregate. Therefore, Nrf1 must be cleaved by a non-proteasomal endoprotease that we show requires ubiquitination. Finally, we provide evidence supporting the recent report that Ddi1/Ddi2 is the critical protease [6,7]. PMID:27676298

  5. 78 FR 38075 - International Labor Comparisons

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-25

    ... Comparisons (ILC) program adjusted foreign data to a common framework of concepts, definitions, and... Productivity and Technology, Bureau of Labor Statistics, Room 2120, 2 Massachusetts Avenue NE., Washington, DC... Productivity and Technology, Bureau of Labor Statistics, telephone number 202-691-6304 (this is not a toll...

  6. Sustainability in Supply Chain Management: Aggregate Planning from Sustainability Perspective.

    PubMed

    Türkay, Metin; Saraçoğlu, Öztürk; Arslan, Mehmet Can

    2016-01-01

    Supply chain management that considers the flow of raw materials, products and information has become a focal issue in modern manufacturing and service systems. Supply chain management requires effective use of assets and information that has far reaching implications beyond satisfaction of customer demand, flow of goods, services or capital. Aggregate planning, a fundamental decision model in supply chain management, refers to the determination of production, inventory, capacity and labor usage levels in the medium term. Traditionally standard mathematical programming formulation is used to devise the aggregate plan so as to minimize the total cost of operations. However, this formulation is purely an economic model that does not include sustainability considerations. In this study, we revise the standard aggregate planning formulation to account for additional environmental and social criteria to incorporate triple bottom line consideration of sustainability. We show how these additional criteria can be appended to traditional cost accounting in order to address sustainability in aggregate planning. We analyze the revised models and interpret the results on a case study from real life that would be insightful for decision makers. PMID:26807848

  7. Sustainability in Supply Chain Management: Aggregate Planning from Sustainability Perspective

    PubMed Central

    Türkay, Metin; Saraçoğlu, Öztürk; Arslan, Mehmet Can

    2016-01-01

    Supply chain management that considers the flow of raw materials, products and information has become a focal issue in modern manufacturing and service systems. Supply chain management requires effective use of assets and information that has far reaching implications beyond satisfaction of customer demand, flow of goods, services or capital. Aggregate planning, a fundamental decision model in supply chain management, refers to the determination of production, inventory, capacity and labor usage levels in the medium term. Traditionally standard mathematical programming formulation is used to devise the aggregate plan so as to minimize the total cost of operations. However, this formulation is purely an economic model that does not include sustainability considerations. In this study, we revise the standard aggregate planning formulation to account for additional environmental and social criteria to incorporate triple bottom line consideration of sustainability. We show how these additional criteria can be appended to traditional cost accounting in order to address sustainability in aggregate planning. We analyze the revised models and interpret the results on a case study from real life that would be insightful for decision makers. PMID:26807848

  8. Sustainability in Supply Chain Management: Aggregate Planning from Sustainability Perspective.

    PubMed

    Türkay, Metin; Saraçoğlu, Öztürk; Arslan, Mehmet Can

    2016-01-01

    Supply chain management that considers the flow of raw materials, products and information has become a focal issue in modern manufacturing and service systems. Supply chain management requires effective use of assets and information that has far reaching implications beyond satisfaction of customer demand, flow of goods, services or capital. Aggregate planning, a fundamental decision model in supply chain management, refers to the determination of production, inventory, capacity and labor usage levels in the medium term. Traditionally standard mathematical programming formulation is used to devise the aggregate plan so as to minimize the total cost of operations. However, this formulation is purely an economic model that does not include sustainability considerations. In this study, we revise the standard aggregate planning formulation to account for additional environmental and social criteria to incorporate triple bottom line consideration of sustainability. We show how these additional criteria can be appended to traditional cost accounting in order to address sustainability in aggregate planning. We analyze the revised models and interpret the results on a case study from real life that would be insightful for decision makers.

  9. Labor productivity losses over western Turkey in the twenty-first century as a result of alteration in WBGT.

    PubMed

    Altinsoy, Hamza; Yildirim, Haci Ahmet

    2015-04-01

    Occupational fatalities and work-related injuries are more common in Turkey than in most developing and developed countries. Several precautions have been taken concerning the matter, and The Occupational Health and Safety Act (OHSL 2012) has been passed. These efforts, however, have failed to incorporate in their framework the role of global warming. New legislation is underway for the prevention of occupational diseases, injuries, and fatalities. This is particularly worrisome given that Turkey is in the forefront of countries projected to be affected seriously by climate change. Consequently, a study on the direct and indirect impact of climate change on workers' health and labour productivity is paramount. The main purpose of this research is to present diminishing labour productivity as a consequence of decreased working hours via an estimate of rest hours of workers in manual labour. The climatic outputs of Regional Climate Model (RegCM3) obtained from the ENSEMBLES Project are used to calculate the wet bulb globe temperature (WBGT) over western Turkey. The study covers the span of years between 1971 and 2100. Moreover, spatial distributions of observed domain are estimated by means of a seasonal analysis, preliminary to a more detailed research. Critical regions, more adversely influenced than others, are identified. The total number of loss days for these critical regions are presented for various time periods. As a result, labour productivity particularly in agriculture and construction is expected to diminish seriously over Central Anatolia, Cyprus, and parts of the Aegean and eastern Mediterranean coastal areas. Between 2071 and 2100, deficiency in labour productivity may reach up to 52% during the summer across some of these critical regions. Though it will be seen that the present study has focused primarily on manual labour and outdoor work in particular, it foreshadows nevertheless the dangerous impact of climate change on occupational health and

  10. Labor productivity losses over western Turkey in the twenty-first century as a result of alteration in WBGT

    NASA Astrophysics Data System (ADS)

    Altinsoy, Hamza; Yildirim, Haci Ahmet

    2015-04-01

    Occupational fatalities and work-related injuries are more common in Turkey than in most developing and developed countries. Several precautions have been taken concerning the matter, and The Occupational Health and Safety Act (OHSL 2012) has been passed. These efforts, however, have failed to incorporate in their framework the role of global warming. New legislation is underway for the prevention of occupational diseases, injuries, and fatalities. This is particularly worrisome given that Turkey is in the forefront of countries projected to be affected seriously by climate change. Consequently, a study on the direct and indirect impact of climate change on workers' health and labour productivity is paramount. The main purpose of this research is to present diminishing labour productivity as a consequence of decreased working hours via an estimate of rest hours of workers in manual labour. The climatic outputs of Regional Climate Model (RegCM3) obtained from the ENSEMBLES Project are used to calculate the wet bulb globe temperature (WBGT) over western Turkey. The study covers the span of years between 1971 and 2100. Moreover, spatial distributions of observed domain are estimated by means of a seasonal analysis, preliminary to a more detailed research. Critical regions, more adversely influenced than others, are identified. The total number of loss days for these critical regions are presented for various time periods. As a result, labour productivity particularly in agriculture and construction is expected to diminish seriously over Central Anatolia, Cyprus, and parts of the Aegean and eastern Mediterranean coastal areas. Between 2071 and 2100, deficiency in labour productivity may reach up to 52 % during the summer across some of these critical regions. Though it will be seen that the present study has focused primarily on manual labour and outdoor work in particular, it foreshadows nevertheless the dangerous impact of climate change on occupational health and

  11. Labor productivity losses over western Turkey in the twenty-first century as a result of alteration in WBGT.

    PubMed

    Altinsoy, Hamza; Yildirim, Haci Ahmet

    2015-04-01

    Occupational fatalities and work-related injuries are more common in Turkey than in most developing and developed countries. Several precautions have been taken concerning the matter, and The Occupational Health and Safety Act (OHSL 2012) has been passed. These efforts, however, have failed to incorporate in their framework the role of global warming. New legislation is underway for the prevention of occupational diseases, injuries, and fatalities. This is particularly worrisome given that Turkey is in the forefront of countries projected to be affected seriously by climate change. Consequently, a study on the direct and indirect impact of climate change on workers' health and labour productivity is paramount. The main purpose of this research is to present diminishing labour productivity as a consequence of decreased working hours via an estimate of rest hours of workers in manual labour. The climatic outputs of Regional Climate Model (RegCM3) obtained from the ENSEMBLES Project are used to calculate the wet bulb globe temperature (WBGT) over western Turkey. The study covers the span of years between 1971 and 2100. Moreover, spatial distributions of observed domain are estimated by means of a seasonal analysis, preliminary to a more detailed research. Critical regions, more adversely influenced than others, are identified. The total number of loss days for these critical regions are presented for various time periods. As a result, labour productivity particularly in agriculture and construction is expected to diminish seriously over Central Anatolia, Cyprus, and parts of the Aegean and eastern Mediterranean coastal areas. Between 2071 and 2100, deficiency in labour productivity may reach up to 52% during the summer across some of these critical regions. Though it will be seen that the present study has focused primarily on manual labour and outdoor work in particular, it foreshadows nevertheless the dangerous impact of climate change on occupational health and

  12. Production of aggregation prone human interferon gamma and its mutant in highly soluble and biologically active form by SUMO fusion technology.

    PubMed

    Tileva, M; Krachmarova, E; Ivanov, I; Maskos, K; Nacheva, G

    2016-01-01

    The Escherichia coli expression system is a preferable choice for production of recombinant proteins. A disadvantage of this system is the target protein aggregation in "inclusion bodies" (IBs) that further requires solubilisation and refolding, which is crucial for the properties and the yield of the final product. In order to prevent aggregation, SUMO fusion tag technology has been successfully applied for expression of eukaryotic proteins, including human interferon gamma (hIFNγ) that was reported, however, with no satisfactory biological activity. We modified this methodology for expression and purification of both the wild type hIFNγ and an extremely prone to aggregation mutant hIFNγ-K88Q, whose recovery from IBs showed to be ineffective upon numerous conditions. By expression of the N-terminal His-SUMO fusion proteins in the E. coli strain BL21(DE3)pG-KJE8, co-expressing two chaperone systems, at 24 °C a significant increase in solubility of both target proteins (1.5-fold for hIFNγ and 8-fold for K88Q) was achieved. Two-step chromatography (affinity and ion-exchange) with on-dialysis His-SUMO-tag cleavage was applied for protein purification that yielded 6.0-7.0mg/g wet biomass for both proteins with >95% purity and native N-termini. The optimised protocol led to increased yields from 5.5 times for hIFNγ up to 100 times for K88Q in comparison to their isolation from IBs. Purified hIFNγ showed preserved thermal stability and antiproliferative activity corresponding to that of the native reference sample (3 × 10(7)IU/mg). The developed methodology represents an optimised procedure that can be successfully applied for large scale expression and purification of aggregation-prone proteins in soluble native form.

  13. Child Labor Requirements in Nonagricultural Occupations under the Fair Labor Standards Act. Child Labor Bulletin No. 101.

    ERIC Educational Resources Information Center

    Employment Standards Administration (DOL), Washington, DC. Wage and Hour Div.

    This booklet is a guide to the provisions of the Fair Labor Standards Act (also known as the Wage-Hour Law) which apply to minors employed in nonagricultural occupations. The content is as follows: coverage of the child labor provisions (covers employees in commerce, the production of goods for commerce, an enterprise engaged in commerce, and an…

  14. Preterm Labor and Birth

    MedlinePlus

    ... Research Information Clinical Trials Resources and Publications Preterm Labor and Birth: Condition Information Skip sharing on social ... links Share this: Page Content What is preterm labor and birth? In general, a normal human pregnancy ...

  15. Preterm Labor and Birth

    MedlinePlus

    ... Research Information Clinical Trials Resources and Publications Preterm Labor and Birth: Overview Skip sharing on social media ... start of the last menstrual period to childbirth. Labor that begins before 37 weeks is called preterm ...

  16. Tips for labor coaches

    MedlinePlus

    ... some tips for getting prepared. Before the big day arrives Labor coaches should go to childbirth classes ... get through her labor and delivery. When the day arrives You might be at the hospital for ...

  17. Labor Education in America

    ERIC Educational Resources Information Center

    Carlson, Kenneth D.

    1971-01-01

    Labor education reflects the pragmaticism of American culture and supports the system. It emphasizes leadership training, loyalty building, and political education. The control of labor education is centralized in union headquarters. (VW)

  18. Utilization of Illinois coal gasification slags for production of ultra-lightweight aggregates. [Quarterly] technical report, March 1--May 31, 1993

    SciTech Connect

    Choudhry, V.; Zimmerle, T.

    1993-09-01

    This research is aimed at testing and developing the expansion potential of gasification solid residues (slag) to manufacture ultra-lightweight aggregates (ULWA). Conventional ULWAs are manufactured by pyroprocessing of perlite or vermiculite ores and have unit weights in the range of 5--15 lb/ ft3. These materials are sold for approximately $200/ton (or $1.00/ft3) and have numerous applications including loose fill insulation, insulating concrete, precast products, filtration media, and agricultural applications. In a previous project, Praxis Engineers demonstrated that lightweight aggregates (LWA) with unit weights of 25--55 lb/ ft3 can be produced from Illinois coal slags and used as substitutes for conventional LWAs. In this program, tests are being undertaken in a pilot-scale vertical shaft furnace to identify operating conditions for the expansion of Illinois slags such that the product can be substituted for ULWA. Upon completion of testing, a large batch of expanded slag will be produced for evaluation in various applications, both in this phase and in subsequent Phase II testing. During the initial pilot plant runs using two Illinois slags, expanded products with unit weights of 12.5--26.5 and 20--52 lb/ ft3, respectively, were produced. Efforts are under way to generate products with lower unit weights.

  19. The Future of Humanities Labor

    ERIC Educational Resources Information Center

    Bauerlein, Mark

    2008-01-01

    "Publish or perish" has long been the formula of academic labor at research universities, but for many humanities professors that imperative has decayed into a simple rule of production. The publish-or-perish model assumed a peer-review process that maintained quality, but more and more it is the bare volume of printed words that counts. When…

  20. Statistical aspects of modeling the labor curve.

    PubMed

    Zhang, Jun; Troendle, James; Grantz, Katherine L; Reddy, Uma M

    2015-06-01

    In a recent review by Cohen and Friedman, several statistical questions on modeling labor curves were raised. This article illustrates that asking data to fit a preconceived model or letting a sufficiently flexible model fit observed data is the main difference in principles of statistical modeling between the original Friedman curve and our average labor curve. An evidence-based approach to construct a labor curve and establish normal values should allow the statistical model to fit observed data. In addition, the presence of the deceleration phase in the active phase of an average labor curve was questioned. Forcing a deceleration phase to be part of the labor curve may have artificially raised the speed of progression in the active phase with a particularly large impact on earlier labor between 4 and 6 cm. Finally, any labor curve is illustrative and may not be instructive in managing labor because of variations in individual labor pattern and large errors in measuring cervical dilation. With the tools commonly available, it may be more productive to establish a new partogram that takes the physiology of labor and contemporary obstetric population into account.

  1. Aggregate exposure modelling of zinc pyrithione in rinse-off personal cleansing products using a person-orientated approach with market share refinement.

    PubMed

    Tozer, Sarah A; Kelly, Seamus; O'Mahony, Cian; Daly, E J; Nash, J F

    2015-09-01

    Realistic estimates of chemical aggregate exposure are needed to ensure consumer safety. As exposure estimates are a critical part of the equation used to calculate acceptable "safe levels" and conduct quantitative risk assessments, methods are needed to produce realistic exposure estimations. To this end, a probabilistic aggregate exposure model was developed to estimate consumer exposure from several rinse off personal cleansing products containing the anti-dandruff preservative zinc pyrithione. The model incorporates large habits and practices surveys, containing data on frequency of use, amount applied, co-use along with market share, and combines these data at the level of the individual based on subject demographics to better estimate exposure. The daily-applied exposure (i.e., amount applied to the skin) was 3.79 mg/kg/day for the 95th percentile consumer. The estimated internal dose for the 95th percentile exposure ranged from 0.01-1.29 μg/kg/day after accounting for retention following rinsing and dermal penetration of ZnPt. This probabilistic aggregate exposure model can be used in the human safety assessment of ingredients in multiple rinse-off technologies (e.g., shampoo, bar soap, body wash, and liquid hand soap). In addition, this model may be used in other situations where refined exposure assessment is required to support a chemical risk assessment.

  2. Aggregate exposure modelling of zinc pyrithione in rinse-off personal cleansing products using a person-orientated approach with market share refinement.

    PubMed

    Tozer, Sarah A; Kelly, Seamus; O'Mahony, Cian; Daly, E J; Nash, J F

    2015-09-01

    Realistic estimates of chemical aggregate exposure are needed to ensure consumer safety. As exposure estimates are a critical part of the equation used to calculate acceptable "safe levels" and conduct quantitative risk assessments, methods are needed to produce realistic exposure estimations. To this end, a probabilistic aggregate exposure model was developed to estimate consumer exposure from several rinse off personal cleansing products containing the anti-dandruff preservative zinc pyrithione. The model incorporates large habits and practices surveys, containing data on frequency of use, amount applied, co-use along with market share, and combines these data at the level of the individual based on subject demographics to better estimate exposure. The daily-applied exposure (i.e., amount applied to the skin) was 3.79 mg/kg/day for the 95th percentile consumer. The estimated internal dose for the 95th percentile exposure ranged from 0.01-1.29 μg/kg/day after accounting for retention following rinsing and dermal penetration of ZnPt. This probabilistic aggregate exposure model can be used in the human safety assessment of ingredients in multiple rinse-off technologies (e.g., shampoo, bar soap, body wash, and liquid hand soap). In addition, this model may be used in other situations where refined exposure assessment is required to support a chemical risk assessment. PMID:26092325

  3. MAJOR AGRICULTURAL MIGRANT LABOR DEMAND AREAS.

    ERIC Educational Resources Information Center

    Department of Labor, Washington, DC.

    DEPICTED ARE 12 CHARTS OF MAJOR CROP PRODUCTION CENTERS IN THE UNITED STATES WHICH DEMAND THE LABOR OF MIGRATORY FARM WORKERS THROUGHOUT THE YEAR. EACH CHART ILLUSTRATES THE AREAS OF AGRICULTURAL MIGRANT LABOR DEMAND FOR ONE MONTH OF THE YEAR. THE PURPOSE IS TO ACQUAINT THE PUBLIC WITH THE COMPLEXITY OF PLACING AND SCHEDULING MIGRATORY WORKERS…

  4. Labor migration in Asia.

    PubMed

    Martin, P L

    1991-01-01

    "A recent conference sponsored by the United Nations Center for Regional Development (UNCRD) in Nagoya, Japan examined the growing importance of labor migration for four major Asian labor importers (Japan, Hong Kong, Malaysia, and Singapore) and five major labor exporters (Bangladesh, Korea, Pakistan, Philippines, and Thailand).... The conference concluded that international labor migration would increase within Asia because the tight labor markets and rising wages which have stimulated Japanese investment in other Asian nations, for example, have not been sufficient to eliminate migration push and pull forces...."

  5. Metabolomic investigation of the anti-platelet aggregation activity of ginsenoside Rk₁ reveals attenuated 12-HETE production.

    PubMed

    Ju, Hyun Kyoung; Lee, Jin Gyun; Park, Mi Kyung; Park, So-Jung; Lee, Chang Hoon; Park, Jeong Hill; Kwon, Sung Won

    2012-10-01

    Comprehensive metabolomics analysis is an effective method of measuring metabolite levels in the body following administration of a pharmaceutical compound and can allow for monitoring of the effects of the compound or assessment of appropriate treatment options for individual patients. In the present metabolomics study, samples pretreated with antiplatelet compounds were extracted and subjected to ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry. The acquired data were processed using peak clustering and evaluated by partial least-squares (PLS) and orthogonal projections to latent structures discriminant analyses (OPLS-DA). As a result, meaningful endogenous metabolites, namely eicosanoids and thromboxane B(2) (TXB(2)), were identified. TXB(2), a key element in platelet aggregation, was decreased upon ginsenoside Rk(1) treatment via inhibition of cyclooxygenase (COX) activity. One of the arachidonic acid (AA) metabolites, 12-hydroxy-5,8,10,14-eicosatetraenoic acid (12-HETE), was decreased significantly in the ginsenoside Rk(1)-treated platelets compared to the AA-induced group. In the mechanism study of ginsenoside Rk(1), a strong linkage to intracellular calcium levels, which induce platelet activation, was found. Additionally, the translocation of 12-LOX from cytosol to membrane, which is related with the intracellular calcium levels, was determined. Therefore, a decreased 12-HETE level induced by ginsenoside Rk(1) on antiplatelet aggregation is related to 12-LOX translocation resulting from decreased Ca(2+) levels. This study shows that global metabolomic analysis has potential for use in understanding the biological behavior of antiplatelet drugs. PMID:22873173

  6. Screening of biotechnical parameters for production of bovine inter-subspecies embryonic chimeras by the aggregation of tetraploid Bos indicus and diploid crossbred Bos taurus embryos.

    PubMed

    Razza, Eduardo M; Satrapa, Rafael A; Emanuelli, Isabele P; Barros, Ciro M; Nogueira, Marcelo F G

    2016-03-01

    The aggregation of a tetraploid zebu embryo (Bos indicus, a thermotolerant breed) with a diploid taurine embryo (Bos taurus, a thermosensitive breed) should create a complete taurine fetus, whose extra-embryonic components, e.g., the chorion, is derived mainly from the zebu embryo. These zebu-derived extra-embryonic components may interact positively with the taurine embryo/fetus during pregnancy in a tropical environment. We tested different parameters for the production of tetraploid Nelore (Bos indicus) embryos to be combined via aggregation with crossbred Bos taurus (diploid) embryos in order to produce viable chimeric blastocysts. Bovine (Bos indicus or crossbred Bos taurus) embryos were produced in vitro according to standard procedures. Two-cell Bos indicus embryos were submitted to electrofusion with varying numbers of pulses (1 or 2), voltages (0.4, 0.5, 0.75, 1.0, 1.4 and 5.0 kV/cm) and time (20, 25, 50 and 60 μs) to produce tetraploid embryos. Electrofused embryos were cultured with crossbred non-fused embryos to form chimeras that developed until the blastocyst stage. The best fusion parameter was 0.75 kV/cm for 60 μs. Four chimeric blastocysts (tetraploid Nelore with diploid crossbred Holstein) were formed after 31 attempts in 4 replicates (13%). We established an optimal procedure for the production of tetraploid Bos indicus (4n) embryos and embryonic chimeras by aggregation of crossbred Bos taurus (2n) with Bos indicus (4n) embryos. This technique would be valid in applied research, by producing exclusively taurine calves, but with placental elements from the Bos indicus breed, following transfer of these chimeras into recipient cows.

  7. Industrial labor relations manual

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The NASA Industrial Labor Relations Manual provides internal guidelines and procedures to assist NASA Field Installations in dealing with contractor labor management disputes, Service Contract Act variance hearings, and to provide access of Labor Union Representatives to NASA for the purpose of maintaining schedules and goals in connection with vital NASA programs. This manual will be revised by page changes as revisions become necessary. Initial distribution of this manual has been made to NASA Headquarters and Field Installations.

  8. Failed induction of labor.

    PubMed

    Schoen, Corina; Navathe, Reshama

    2015-10-01

    Induction of labor will affect almost a quarter of all pregnancies, but historically there has been no generally accepted definition of failed induction of labor. Only recently have studies analyzed the lengths of latent labor that are associated with successful labor induction ending in a vaginal delivery, and recommendations for uniformity in the diagnosis of failed induction have largely resulted from this data. This review assesses the most recent and inclusive definition for failed induction, risk factors associated with failure, complications, and special populations that may be at risk for a failed induction.

  9. Immunogenicity of Therapeutic Protein Aggregates.

    PubMed

    Moussa, Ehab M; Panchal, Jainik P; Moorthy, Balakrishnan S; Blum, Janice S; Joubert, Marisa K; Narhi, Linda O; Topp, Elizabeth M

    2016-02-01

    Therapeutic proteins have a propensity for aggregation during manufacturing, shipping, and storage. The presence of aggregates in protein drug products can induce adverse immune responses in patients that may affect safety and efficacy, and so it is of concern to both manufacturers and regulatory agencies. In this vein, there is a lack of understanding of the physicochemical determinants of immunological responses and a lack of standardized analytical methods to survey the molecular properties of aggregates associated with immune activation. In this review, we provide an overview of the basic immune mechanisms in the context of interactions with protein aggregates. We then critically examine the literature with emphasis on the underlying immune mechanisms as they relate to aggregate properties. Finally, we highlight the gaps in our current understanding of this issue and offer recommendations for future research. PMID:26869409

  10. Product and process understanding to relate the effect of freezing method on glycation and aggregation of lyophilized monoclonal antibody formulations.

    PubMed

    Awotwe-Otoo, David; Agarabi, Cyrus; Read, Erik K; Lute, Scott; Brorson, Kurt A; Khan, Mansoor A

    2015-07-25

    The objective of the study was to analyze the effect of controlled and uncontrolled freezing step of a lyophilization process on the extent of non-enzymatic glycation and aggregation of an IgG1 formulation at two concentrations (1mg/ml and 20mg/ml). The degree of glycation (%) was determined through boronate affinity chromatography and its effect on the formation of soluble aggregates and higher molecular weight species was studied using dynamic light scattering (DLS) and size exclusion chromatography with multi-angle light scattering (SEC-MALS). The effect of non-enzymatic glycation on the secondary structure of the formulations was also studied using circular dichroism (CD) spectroscopy and Fourier transform infrared (FT-IR) spectroscopy. Results indicated that controlled nucleation yielded higher residual moisture contents and significantly lower specific surface areas for the two monoclonal antibody concentrations compared with uncontrolled nucleation cycle (p<0.05). For the two concentrations, uncontrolled nucleation resulted in significantly higher levels of glycation compared with controlled nucleation samples (p<0.05). Further, it was observed that higher storage temperatures (25°C/60% RH) versus 5°C resulted in higher glycation. Even though SEC-MALS analyses of the low concentrated formulations did not reveal the formation of higher molecular weight species, DLS analyses at two storage conditions revealed increases in the hydrodynamic radii and polydispersity index of the reconstituted formulations, suggesting the onset of formation of smaller species in the formulations. CD spectroscopy did not reveal any differences in the secondary structure of the mAb for the two concentrations after lyophilization. In conclusion, the freezing step method impacted the extent of glycation in lyophilized samples and the hydrolyzed component of sucrose was critical for increasing glycation. Even though some level of glycation was observed in lyophilized samples, the

  11. Production of chimeric embryos by aggregation of bovine egfp eight-cell stage blastomeres with two-cell fused and asynchronic embryos.

    PubMed

    Hiriart, M I; Bevacqua, R J; Canel, N G; Fernández-Martín, R; Salamone, D F

    2013-09-01

    Embryo disaggregation allows the production of two to four identical offspring from a single cow embryo. In addition, embryo complementation has become the technique of choice to demonstrate the totipotency of embryonic stem cells and induced pluripotent stem cells. Therefore, the aim of this study was to generate a new and simple method by aggregation in the well-of-the-well system to direct each single enhanced green fluorescent protein (egfp) eight-cell blastomere derived from bovine in vitro fertilization embryos to the inner cell mass (ICM) of chimeras produced with fused and asynchronic embryos. To this end, the best conditions to generate in vitro fertilization-fused embryos were determined. Then, the fused (F) and nonfused (NF) embryos were aggregated in two distinct conditions: synchronically (S), with both transgenic and F embryos produced on the same day, and asynchronically (AS), with transgenic embryos produced one day before F embryos. The highest fusion and blastocysts rates were obtained with two pulses of 40 V. The 2ASF and 2ASNF groups showed the best number of blastocysts expressing the EGFP protein (48% and 41%, respectively). Furthermore, the 2ASF group induced the highest localization rates of the egfp-expressing blastomere in the ICM (6/13, 46% of ICM transgene-expressing blastocysts). This technique will have great application for multiplication of embryos of high genetic value or transgenic embryos and also with the generation of truly bovine embryonic stem cells and induced pluripotent stem cells.

  12. Guarana (Paullinia cupana Mart.) prevents β-amyloid aggregation, generation of advanced glycation-end products (AGEs), and acrolein-induced cytotoxicity on human neuronal-like cells.

    PubMed

    Bittencourt, Leonardo da Silva; Zeidán-Chuliá, Fares; Yatsu, Francini Kiyono Jorge; Schnorr, Carlos Eduardo; Moresco, Karla Suzana; Kolling, Eduardo Antônio; Gelain, Daniel Pens; Bassani, Valquiria Linck; Moreira, José Cláudio Fonseca

    2014-11-01

    Advanced glycation end-products (AGEs) are considered potent molecules capable of promoting neuronal cell death and participating in the development of neurodegenerative disorders such as Alzheimer's disease (AD). Previous studies have shown that AGEs exacerbate β-amyloid (Aβ) aggregation and AGE-related cross-links are also detected in senile plaques. Acrolein (ACR) is an α, β-unsaturated aldehyde found in the environment and thermally processed foods, which can additionally be generated through endogenous metabolism. The role of ACR in AD is widely accepted in the literature. Guarana (Paullinia cupana Mart.) is popularly consumed by the population in Brazil, mainly for its stimulant activity. In the present study, we showed that guarana (10, 100, and 1000 µg/mL) is able to prevent protein glycation, β-amyloid aggregation, in vitro methylglyoxal, glyoxal, and ACR (20 μM)-induced toxicity on neuronal-like cells (SH-SY5Y). Since these are considered typical AD pathological hallmarks, we propose that guarana may deserve further research as a potential therapeutic agent in such a neurodegenerative disease. PMID:24840232

  13. Guarana (Paullinia cupana Mart.) prevents β-amyloid aggregation, generation of advanced glycation-end products (AGEs), and acrolein-induced cytotoxicity on human neuronal-like cells.

    PubMed

    Bittencourt, Leonardo da Silva; Zeidán-Chuliá, Fares; Yatsu, Francini Kiyono Jorge; Schnorr, Carlos Eduardo; Moresco, Karla Suzana; Kolling, Eduardo Antônio; Gelain, Daniel Pens; Bassani, Valquiria Linck; Moreira, José Cláudio Fonseca

    2014-11-01

    Advanced glycation end-products (AGEs) are considered potent molecules capable of promoting neuronal cell death and participating in the development of neurodegenerative disorders such as Alzheimer's disease (AD). Previous studies have shown that AGEs exacerbate β-amyloid (Aβ) aggregation and AGE-related cross-links are also detected in senile plaques. Acrolein (ACR) is an α, β-unsaturated aldehyde found in the environment and thermally processed foods, which can additionally be generated through endogenous metabolism. The role of ACR in AD is widely accepted in the literature. Guarana (Paullinia cupana Mart.) is popularly consumed by the population in Brazil, mainly for its stimulant activity. In the present study, we showed that guarana (10, 100, and 1000 µg/mL) is able to prevent protein glycation, β-amyloid aggregation, in vitro methylglyoxal, glyoxal, and ACR (20 μM)-induced toxicity on neuronal-like cells (SH-SY5Y). Since these are considered typical AD pathological hallmarks, we propose that guarana may deserve further research as a potential therapeutic agent in such a neurodegenerative disease.

  14. Managing pain during labor

    MedlinePlus

    ... health care provider about the different types of pain relief for your labor and delivery. The health and safety of you and your ... so your doctor may recommend one type of pain relief for you over ... so you can make the best plan for your labor and delivery.

  15. Effects of Recombinant Human Megakaryocyte Growth and Development Factor (rHuMGDF) on Platelet Production, Platelet Aggregation, and Thrombosis.

    PubMed

    Lott; Nelson; Toombs

    1998-01-01

    Recombinant human megakaryocyte growth and development factor (rHuMGDF) is a c-mpl ligand that promotes the differentiation of CD34+ precursor cells into megakaryocyte, and then platelets. In experimental animals, injection of this and other c-mpl ligands leads to profound increases in the circulating platelet count in a matter of days. However, c-mpl ligands have also been shown to sensitize platelets to aggregating agents in vitro, raising the possibility that c-mpI ligands may have prothrombotic effects in vivo. Therefore, characterizing rHuMGDF in an in vivo model of thrombosis is a necessary and critical step in defining the in vivo pharmacology of this novel and important hernatopoietic factor, a pegylated form of which is currently in clinical trials. To determine the biologically effective doses in the rabbit, daily subcutaneous injections of rHuMGDF at 0.1, 1.0, or 10 µg/kg were administered ever 7 days. Daily injection of 10 µ/kg produced an approximate fourfold increase in platelet count and 1.0 µ/kg doubled platelet count over the injection period, both of which were statistically significant. The serum concentrations of rHuMGDF were determined 10 minutes following a single intravenous injection with 0.1, 1.0, and 10 µ/kg, and were 0.05 +/- 0.02, 0.98 +/- 0.07, and 21.32 +/- 21.35 ng/ml. To determine whether rHuMGDF can sensitize platelets in vivo, platelet aggregometry was performed on platelets isolated from animals immediately before and 10 minutes after they had been injected intravenously with rHuMGDF (0.1, 1.0, and 10 µ/kg). Intravenous injection of 10 µ/kg produced measurable changes in platelet aggregometry ex vivo, as evidenced by an increased sensitivity of platelets to adenosine diphosphate (ADP). To assess. the in vivo prothrombotic potential of rHuMGDF, a rabbit carotid artery model of cyclic flow reduction (CFR) was used to measure the effect of intravenous rHuMGDF administration on the rate of thrombus formation as assessed by CFR

  16. Therapeutic showering in labor.

    PubMed

    Stark, Mary Ann

    2013-08-01

    While showering is thought to be an effective coping strategy during labor, research on this comfort measure is lacking. The purpose of this study was to measure effectiveness of therapeutic showering on pain, coping, tension, anxiety, relaxation, and fatigue in labor. A quasi-experimental pretest-posttest single group design was conducted in a community hospital. Participants were women who had singleton, uncomplicated pregnancies and were in active labor at term (N = 24). After completing pretest measures, participants took a 30 min shower where they were encouraged to be seated but could choose positions of comfort. There were significant reductions in tension and anxiety and increased relaxation and coping. Showering may be a safe and effective comfort measure for healthy, laboring women who are experiencing tension or anxiety, or having difficulty relaxing or coping with labor. Further research is needed to test the maternal and neonatal outcomes of this nonpharmacologic comfort measure.

  17. Fractal aggregates in Titan's atmosphere

    NASA Astrophysics Data System (ADS)

    Cabane, M.; Rannou, P.; Chassefiere, E.; Israel, G.

    1993-04-01

    The cluster structure of Titan's atmosphere was modeled by using an Eulerian microphysical model with the specific formulation of microphysical laws applying to fractal particles. The growth of aggregates in the settling phase was treated by introducing the fractal dimension as a parameter of the model. The model was used to obtain a vertical distribution of size and number density of the aggregates for different production altitudes. Results confirm previous estimates of the formation altitude of photochemical aerosols. The vertical profile of the effective radius of aggregates was calculated as a function of the visible optical depth.

  18. Utilization of Illinois coal gasification slags for production of ultra-lightweight aggregates. Final technical report, September 1, 1992--August 31, 1993

    SciTech Connect

    Choudhry, V.; Zimmerle, T.

    1993-12-31

    This research was aimed at testing and developing the expansion potential of solid residues (slag) from gasification of Illinois coals to manufacture ultra-lightweight aggregates (ULWA). Conventional ULWAs are manufactured by pyroprocessing perlite or vermiculite ores and have unit weights in the 5--12 lb/ ft{sup 3} range. These materials sell for approximately $200/ton ($1.00/ft{sup 3}) and have numerous applications. The incentive for this effort was based on previous experimental results in which lightweight aggregates (LWA) with unit weights of 25--55 lb/ft{sup 3} were produced from Illinois slag using a direct-fired furnace. In this program, bench-scale expansion tests conducted with two Illinois coal slags resulted in product unit weights of 12 and 18.5 lb/ ft{sup 3}, thus confirming the feasibility of producing ULWA from Illinois slags. During initial pilot vertical shaft furnace test runs, two Illinois slags were expanded to generate products with unit weights of 12.5--26.5 and 20--52 lb/ ft{sup 3}. Further attempts to lower the product unit weights resulted in fusion of the slag. This problem could be overcome by methods including surface treatment of the slag, blending the slag with other materials, or utilization of indirect firing methods. To lower the product unit weights, an indirect-fired horizontal shaft furnace was used and products with unit weights of 12.4--52.0 lb/ft{sup 3} were generated, thus indicating that this method can be used to produce a wide range of expanded products. A large batch of expanded slag was produced using an 18-in. diameter x 12-ft long indirect-fired pilot furnace. A sample from this batch was characterized. Specimens of insulating concrete made from expanded slag had a unit weight 43.3 lb/ft{sup 3} and thermal conductivity of 1.34 Btu-in./h/ft{sup 2}/{degrees}F. This compares well with a value of 1. 2 Btu-in./h/ft{sup 2}/{degrees}F for insulating concrete of a similar weight made from perlite, as per ASTM C 332-82.

  19. Project LEAP: The Labor Education Achievement Program. A Program To Improve the Literacy Level and Productivity of the Workforce. Final Project Report. April 1, 1991-September 30, 1992.

    ERIC Educational Resources Information Center

    Metropolitan Baltimore Council of AFL-CIO Unions, MD.

    Maryland's Labor Education Achievement Program (LEAP) worked with a wide diversity of union workers in multiple industries and within numerous private companies and public agencies over a dispersed geographic area. Staff development included a workshop for local coordinators and a teacher inservice training session. LEAP provided…

  20. Strategies for getting through labor

    MedlinePlus

    ... your labor coach More about how to manage pain during labor, such as epidural and other medicines Having a ... a long way in helping you deal with pain. Use your labor coach. Tell them what they can do to ...

  1. Trends in preterm labor.

    PubMed

    Graf, R A; Perez-Woods, R

    1992-03-01

    Preterm birth has been identified by the National Commission to Prevent Infant Mortality (1988) as the primary cause of the increased infant mortality rate in the United States. An analysis of what is currently known about four areas of preterm labor including (1) definition and causes, (2) identification of patients at risk, (3) management techniques, and (4) use of patient education in labor is presented in this paper. Preterm labor is defined as uterine contractions that occur between 20 and 37 weeks' gestation with progressive cervical dilatation or effacement or both. Directions for future research are discussed.

  2. Sectoral shifts and aggregate unemployment

    SciTech Connect

    Loungani, P.

    1986-01-01

    Some recent research has taken the view that sectoral or industry-specific shocks significantly affect aggregate unemployment by increasing the amount of inter-industry labor reallocation required. The empirical evidence for this view rests on the finding that during the 1950s - and again during the 1970s - there was a positive correlation between aggregate unemployment and the dispersion of employment growth rates. This thesis demonstrates that this correlation arises largely because oil price shocks affect both unemployment and the dispersion of employment growth. Once the dispersion due to oil shocks is accounted for, the residual dispersion in employment has very low explanatory power for unemployment. Since the dispersion index does not measure pure sectoral shifts, an alternate measure of dispersion is developed that serves as a better proxy for the amount of inter-industry labor reallocation required each period. Estimates using this measure suggest that, during the 1950s, temporary increases in the relative price of oil were responsible for generating the observed correlation. On the other hand, sectoral shifts were important during the 1970s; in particular, the 1973 oil price increase has had significant reallocative effects on the economy. This contention is subjected to further tests by looking at the time-series behavior of employment in durable-goods industries and also by following the inter-industry movements of workers over time through the use of panel data.

  3. Small angle x-ray scattering: Instrument development and studies of protein aggregation, cellulose hydrolysis, and the production of nanoporous metals using surfactact templates

    NASA Astrophysics Data System (ADS)

    Banuelos, Jose Leobardo

    Small angle x-ray scattering (SAXS) was used to obtain structural insights into protein aggregation, the enzymatic hydrolysis of cellulose, and the structural evolution of surfactant-templated nanoporous palladium and platinum systems during their synthesis. SAXS is bulk technique that allows probing the nanometer-scale morphology, interactions, density, and distribution of a variety of nonperiodic systems in the solid, liquid, or gaseous state. A 10-meter Small Angle Scattering camera, originally at ORNL, was assembled. During its re-commissioning, several upgrades were made including new data acquisition software built using National Instrument's Labview development environment, as well as portability to use analysis tools in wide use in scattering community. The Multiple Energy Diffractometer Using Small, medium and wide Angles (MEDUSA) was designed and built, its development will be discussed. The ability of proteins to change their conformation in response to changes in pressure, temperature, the presence of other molecular species, and ionic concentration in the solvents they are found, is a remarkable phenomenon that allows living cells to function properly. When proteins irreversibly unfold or mis-fold and aggregate this gives rise to severely debilitating diseases such as Alzheimer's and prion diseases. Protein aggregation was measured using SAXS on aqueous solutions of bovine serum albumin, myoglobin, and cellulase enzymes. Understanding how cellulose can be broken down into fermentable sugars is an important step in the development of strategies for producing alternative energy from biomass. The enzymatic hydrolysis of cellulose was studied using both small angle neutron scattering and SAXS. One result from these investigations was finding supporting evidence that nanopores within the cellulose fibril matrix allow biologically active enzymes access to digest parts of the fibers. The production of mesoporous materials for hydrogen storage applications was

  4. Treatments for Preterm Labor

    MedlinePlus

    ... leader Partner Spotlight Become a partner World Prematurity Day What's happening in your area Find out about ... may delay labor, often for just a few days. This delay may give you time to get ...

  5. [Active management of labor].

    PubMed

    Ruiz Ortiz, E; Villalobos Román, M; Flores Murrieta, G; Sotomayor Alvarado, L

    1991-01-01

    Eighty three primigravidae patients at the end of latency labor, erased cervix, 3 cm dilation, vertex presentation and adequate pelvis, were studied. Two groups were formed: 53 patients in the study group, who received active management of labor, and 30 patients in the control group, treated in the traditional way. In all the patients a graphic recording of labor, was carried out; it included all the events, and as labor advanced, a signoidal curve of cervical dilatation, was registered, as well as the hyperbolic one for presentation descent. The study group received the method in a systematized manner, as follows: 1. Peridular block. 2. Amniotomy. 3. IV oxytocin one hour after amniotomy. 4. FCR monitoring. 5. Detection of dystocia origin. Materno-fetal morbidity was registered in both groups, as well as cesarean section rate, instrumental delivery and its indications, labor duration, and time of stay in labor room. Diminution of above intems and opportune detection of dystocia, were determined. It was concluded that a constructive action plan, starting at hospital admission in most healthy women, allows a normal delivery of brief duration.

  6. The Minimum Wage, Restaurant Prices, and Labor Market Structure

    ERIC Educational Resources Information Center

    Aaronson, Daniel; French, Eric; MacDonald, James

    2008-01-01

    Using store-level and aggregated Consumer Price Index data, we show that restaurant prices rise in response to minimum wage increases under several sources of identifying variation. We introduce a general model of employment determination that implies minimum wage hikes cause prices to rise in competitive labor markets but potentially fall in…

  7. Thermostable keratinase from Bacillus pumilus KS12: production, chitin crosslinking and degradation of Sup35NM aggregates.

    PubMed

    Rajput, Rinky; Gupta, Rani

    2013-04-01

    Production of thermostable keratinase from Bacillus pumilus KS12 was enhanced up to seven fold by statistical methods. The enzyme was partially purified by ultrafiltration followed by thermal precipitation with purity of 3.2-fold and recovery of 89%. Keratinase was immobilized using covalent method by crosslinking 2 mg protein (688 U/mg) onto 1g chitin activated with 2.5% (v/v) glutaraldehyde for 60 min. Its comparative biochemical studies with that of free keratinase revealed the shift in optimum pH with increased stability towards pH from 9.0 to 10.0 and temperature. Also, it showed statistically significant improved hydrolysis of a number of soluble and insoluble substrates in comparison to free keratinase. Owing to improved catalytic efficiency of immobilized keratinase, its potential for degradation of Sup35NM was evaluated, where 100 μg of enzyme could degrade 60 μg Sup35NM after 60 min at pH 7.0 and 37°C.

  8. Wages and Labor Management in African Manufacturing

    ERIC Educational Resources Information Center

    Fafchamps, Marcel; Soderbom, Mans

    2006-01-01

    Using matched employer-employee data from ten African countries, we examine the relationship between wages, worker supervision, and labor productivity in manufacturing. Wages increase with firm size for both production workers and supervisors. We develop a two-tier model of supervision that can account for this stylized fact and we fit the…

  9. Labor Used on U.S. Farms, 1964-1966.

    ERIC Educational Resources Information Center

    Sellers, Walter E., Jr.

    Such factors as type of farm, farm production region, and farm size affect the percentage of farms hiring workers, the number of hours worked by hired workers, the length of the farm workweek, and the hours of labor used per $100 of sales. Labor costs and shortages most directly affected farms that sold $20,000 or more of farm products in 1964 and…

  10. Electromagnetic charges in aggregation phenomena.

    NASA Astrophysics Data System (ADS)

    Rioux, Claude; Slobodrian, R. J.

    the aggregations. From these results, we believe that we can discriminate between the two forces and knowing the constants, it will be possible to obtain the product of the charges (or of the magnetic moments) without disturbing the aggregation process. This will result in a powerful diagnostic instrument to further the study of the fine powder aggregation mechanism. [1] A. Block, W. von Bloh and H.J. Schellnhuber, J. Phys. A 24, L1037 (1991). [2] C. Rioux, L. Potvin and R.J. Slobodrian, Phys. Rev. E, vol. 52, p. 2099 (1995).

  11. Second stage of labor.

    PubMed

    Cheng, Yvonne W; Caughey, Aaron B

    2015-06-01

    Current American College of Obstetricians and Gynecologists' definition of prolonged second stage diagnoses 10% to 14% of nulliparous and 3% to 3.5% of multiparous women as having a prolonged second stage. The progression of labor in modern obstetrics may have deviated from the current labor norms established in the 1950s, likely due to differences in obstetric population characteristics and variation in clinical practice. Optimal management of the second stage in women with and without epidural remains debatable. Although prolonged second stage is associated with increased risk of maternal morbidity, conflicting data exist regarding the duration of second stage and associated neonatal morbidity and mortality.

  12. Ash Aggregates in Proximal Settings

    NASA Astrophysics Data System (ADS)

    Porritt, L. A.; Russell, K.

    2012-12-01

    early pyroclastic phase of the formation of Kima'Kho, a tuya in northern B.C., Canada produced a subaqueous pyroclastic cone which became emergent during the latter stages of formation. Armoured lapilli are pervasive within the emergent upper third of the sequence. No other types of ash aggregates have been observed. Petrographic and textural analysis of the armoured lapilli shows them to comprise a central 2-30 mm-sized, juvenile, vesiculated pyroclast, concentrically coated by mm-scale layers of 10-250 μm sized ash particles. At Kima'Kho, the armoured lapilli are shown to be a direct indicator of fallout from a sustained plume attended by concomitant production of pyroclastic density currents. The size and internal structure of the armoured lapilli provide constraints on the nature of the initial explosive phase of eruption at Kima'Kho. Their proximity to the vent also indicates rapid aggregation within the eruption plume. Within both sequences rapid aggregation of ash particles occurred in proximity to the vent. However, the conditions were substantially different leading to the production of armoured lapilli (no accretionary lapilli) at Kima'Kho and diverse ash aggregates but no armoured lapilli at A418. Here we investigate vent-proximal ash aggregation and the specific conditions which lead to the formation of coated ash pellets and armoured lapilli.

  13. Cultivating Labor Management Collaboration

    ERIC Educational Resources Information Center

    Spector, Stacy

    2013-01-01

    In many districts, the notion of labor groups and district administration working together conjures descriptions of war and battle rather than cooperation and collaboration. However, in San Juan Unified School District, the headline, "Union and District Exhibit Positive Partnership" exemplifies the changing relationship between teacher leaders and…

  14. Labor Issues. Transition Series.

    ERIC Educational Resources Information Center

    Comptroller General of the U.S., Washington, DC.

    Major policy, management, and program issues face the Congress and new administration in the area of labor. Many of the nation's youth are leaving school poorly prepared for the new work world. The nation already has a large group of economically disadvantaged people who lack necessary skills. Annually, 900,000 or more workers are at least…

  15. Labor Market Progeria.

    ERIC Educational Resources Information Center

    Rodeheaver, Dean

    1990-01-01

    Social ambivalence toward women's roles, sexuality, appearance, and aging combine with social standards of attractiveness to create both age and sex discrimination in the workplace. The life expectancy of presentability is shorter among women than men, thus creating an accelerated aging process termed labor market progeria. (SK)

  16. Thermodynamics of Protein Aggregation

    NASA Astrophysics Data System (ADS)

    Osborne, Kenneth L.; Barz, Bogdan; Bachmann, Michael; Strodel, Birgit

    Amyloid protein aggregation characterizes many neurodegenerative disorders, including Alzheimer's, Parkinson's, and Creutz- feldt-Jakob disease. Evidence suggests that amyloid aggregates may share similar aggregation pathways, implying simulation of full-length amyloid proteins is not necessary for understanding amyloid formation. In this study we simulate GNNQQNY, the N-terminal prion-determining domain of the yeast protein Sup35 to investigate the thermodynamics of structural transitions during aggregation. We use a coarse-grained model with replica-exchange molecular dynamics to investigate the association of 3-, 6-, and 12-chain GNNQQNY systems and we determine the aggregation pathway by studying aggregation states of GN- NQQNY. We find that the aggregation of the hydrophilic GNNQQNY sequence is mainly driven by H-bond formation, leading to the formation of /3-sheets from the very beginning of the assembly process. Condensation (aggregation) and ordering take place simultaneously, which is underpinned by the occurrence of a single heat capacity peak only.

  17. Gut bacteria mediate aggregation in the German cockroach

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Aggregation of the German cockroach, Blattella germanica, is regulated by fecal aggregation agents (pheromones), including volatile carboxylic acids (VCAs). We hypothesized that the gut microbial community contributes to production of these semiochemicals. Chemical analysis of the fecal extract of B...

  18. INTERNAL LABOR MARKETS, TECHNOLOGICAL CHANGE, AND LABOR FORCE ADJUSTMENT.

    ERIC Educational Resources Information Center

    DOERINGER, PETER B.; PIORE, MICHAEL J.

    DIFFERENCES BETWEEN LABOR FORCE SKILLS AND THE REQUIREMENTS OF BLUE COLLAR JOBS ARE RECONCILED BY MEANS OVER WHICH THE EMPLOYER, ALONE OR WITH A LABOR ORGANIZATION, EXERCISES CONTROL. THE ADJUSTMENT MODEL PRESENTED IN THIS STUDY RECOGNIZES AN INPLANT LABOR MARKET CONNECTED TO THE EXTERNAL MARKET AT A LIMITED NUMBER OF POINTS. CERTAIN…

  19. Natural aggregates of the conterminous United States

    USGS Publications Warehouse

    Langer, William H.

    1988-01-01

    adversely when used as concrete aggregate. In areas where suitable natural aggregate is not available or accessible, it may become necessary to improve the quality of existing aggregate, to import aggregate from outside the area, or to substitute artificial aggregate for natural aggregate. In most cases, all of these alternatives add substantially to the cost of the final product. Even though an area may be blessed with an abundance of aggregate suitable for the intended purpose, existing land uses, zoning, or regulations may preclude commercial exploitation of the aggregate. This report also discusses the aggregate industry in general terms, including exploration, mining, and processing, as well as aggregate production rates. Proper long-range planning based on an understanding of the aggregate industry can help assure adequate supplies of aggregate.

  20. Child Labor in America's History

    ERIC Educational Resources Information Center

    Goldstein, Harold

    1976-01-01

    A brief history of child labor and the fight for legislation to control it at both the state and federal level. The current legal status and the continued existence of child labor in modern times are also discussed. (MS)

  1. Interpersonal Styles and Labor Market Outcomes

    ERIC Educational Resources Information Center

    Borghans, Lex; Weel, Bas ter; Weinberg, Bruce A.

    2008-01-01

    This paper develops a framework of the role of interpersonal interactions in the labor market. Effective interpersonal interactions involve caring and directness. The ability to perform these tasks varies with personality and the importance of these tasks varies across jobs. An assignment model shows that people are most productive in jobs that…

  2. Origins of the Sexual Division of Labor.

    ERIC Educational Resources Information Center

    Leibowitz, Lila

    An interactive, biosocial model of early hominids presents evidence that physical sex differences are not the basis for the sexual division of labor as is commonly believed. Production (the deliberate collection and distribution of food) developed among early hominids as a prerequisite for survival. Although the population appears to have had…

  3. Cognitive Capitalism, Education and Digital Labor

    ERIC Educational Resources Information Center

    Peters, Michael A., Ed.; Bulut, Ergin, Ed.

    2011-01-01

    Cognitive capitalism--sometimes referred to as "third capitalism," after mercantilism and industrial capitalism--is an increasingly significant theory, given its focus on the socio-economic changes caused by Internet and Web 2.0 technologies that have transformed the mode of production and the nature of labor. The theory of cognitive capitalism…

  4. Murphy's Moral Economy of Labor.

    ERIC Educational Resources Information Center

    Masters, Roger D.

    1996-01-01

    Praises and summarizes James Bernard Murphy's "The Moral Economy of Labor: Aristotelian Themes in Economic Theory." Linking economic theories from Adam Smith to Karl Marx, Murphy criticizes traditional economic and social thinking regarding the division of labor. He proposes an integration of conceptualization and execution to humanize labor. (MJP)

  5. Labor Arbitration and Dispute Resolution.

    ERIC Educational Resources Information Center

    Getman, Julius G.

    1979-01-01

    Discusses the nature of labor arbitration; then explores the transferability of the labor arbitration model. Argues that the establishment and legitimation of unions and collective bargaining are responsible for the success of labor arbitration, not vice versa. Available from The Yale Law Journal, 401A Yale Station, New Haven, Connecticut 06520;…

  6. Institutions of Higher Education Under the Fair Labor Standards Act.

    ERIC Educational Resources Information Center

    Employment Standards Administration (DOL), Washington, DC. Wage and Hour Div.

    The Fair Labor Standards Act contains provisions and standards concerning minimum wages, equal pay, maximum hours and overtime pay, recordkeeping, and child labor. These basic requirements apply to employees engaged in interstate commerce or in the production of goods for interstate commerce and also to employees in certain enterprises that are so…

  7. High Technology, Work, and Inequality in Southern Labor Markets.

    ERIC Educational Resources Information Center

    Colclough, Glenna; Tolbert, Charles M., II

    1990-01-01

    Explores the relationship among high technology industrialization, skill levels, and economic inequality. Finds that minority labor force participants experience more earnings discrimination in high tech industries than in other industries. Attributes findings to variations in local labor market contexts and to differing stages of product cycles…

  8. Environmentalism and natural aggregate mining

    USGS Publications Warehouse

    Drew, L.J.; Langer, W.H.; Sachs, J.S.

    2002-01-01

    living space has encroached on the sites of production; in other words, the act of production has engendered condemnation. Many other environmental problems that are associated with dust and noise and blasting from quarry and pit operations have been reduced through the efficient use of technology. Recycling concrete in buildings, bridges, and roads and asphaltic pavements will ultimately reduce the demand for virgin natural aggregate. The impact created by the large holes in the ground required for the mining of natural aggregate can be greatly reduced by planning their reclamation before mining begins. ?? 2002 International Association for Mathematical Geology.

  9. Immunogenicity of therapeutic proteins: influence of aggregation.

    PubMed

    Ratanji, Kirsty D; Derrick, Jeremy P; Dearman, Rebecca J; Kimber, Ian

    2014-01-01

    The elicitation of anti-drug antibodies (ADA) against biotherapeutics can have detrimental effects on drug safety, efficacy, and pharmacokinetics. The immunogenicity of biotherapeutics is, therefore, an important issue. There is evidence that protein aggregation can result in enhanced immunogenicity; however, the precise immunological and biochemical mechanisms responsible are poorly defined. In the context of biotherapeutic drug development and safety assessment, understanding the mechanisms underlying aggregate immunogenicity is of considerable interest. This review provides an overview of the phenomenon of protein aggregation, the production of unwanted aggregates during bioprocessing, and how the immune response to aggregated protein differs from that provoked by non-aggregated protein. Of particular interest is the nature of the interaction of aggregates with the immune system and how subsequent ADA responses are induced. Pathways considered here include 'classical' activation of the immune system involving antigen presenting cells and, alternatively, the breakdown of B-cell tolerance. Additionally, methods available to screen for aggregation and immunogenicity will be described. With an increased understanding of aggregation-enhanced immune responses, it may be possible to develop improved manufacturing and screening processes to avoid, or at least reduce, the problems associated with ADA.

  10. Directional sensing and streaming in Dictyostelium aggregation.

    PubMed

    Almeida, Sofia; Dilão, Rui

    2016-05-01

    We merge the Kessler-Levine simple discrete model for Dictyostelium cyclic adenosine monophosphate (cAMP) production and diffusion with the Dilão-Hauser directional sensing aggregation mechanism. The resulting compound model describes all the known transient patterns that emerge during Dictyostelium aggregation, which include the spontaneous formation of cAMP self-sustained target and spiral waves and streaming. We show that the streaming patterns depend on the speed of the amoebae, on the relaxation time for the production of cAMP, on the cAMP degradation rate, and on directional sensing. Moreover, we show that different signaling centers emerge during Dictyostelium aggregation. PMID:27300919

  11. Directional sensing and streaming in Dictyostelium aggregation

    NASA Astrophysics Data System (ADS)

    Almeida, Sofia; Dilão, Rui

    2016-05-01

    We merge the Kessler-Levine simple discrete model for Dictyostelium cyclic adenosine monophosphate (cAMP) production and diffusion with the Dilão-Hauser directional sensing aggregation mechanism. The resulting compound model describes all the known transient patterns that emerge during Dictyostelium aggregation, which include the spontaneous formation of cAMP self-sustained target and spiral waves and streaming. We show that the streaming patterns depend on the speed of the amoebae, on the relaxation time for the production of cAMP, on the cAMP degradation rate, and on directional sensing. Moreover, we show that different signaling centers emerge during Dictyostelium aggregation.

  12. Directional sensing and streaming in Dictyostelium aggregation.

    PubMed

    Almeida, Sofia; Dilão, Rui

    2016-05-01

    We merge the Kessler-Levine simple discrete model for Dictyostelium cyclic adenosine monophosphate (cAMP) production and diffusion with the Dilão-Hauser directional sensing aggregation mechanism. The resulting compound model describes all the known transient patterns that emerge during Dictyostelium aggregation, which include the spontaneous formation of cAMP self-sustained target and spiral waves and streaming. We show that the streaming patterns depend on the speed of the amoebae, on the relaxation time for the production of cAMP, on the cAMP degradation rate, and on directional sensing. Moreover, we show that different signaling centers emerge during Dictyostelium aggregation.

  13. 48 CFR 222.101 - Labor relations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... OF DEFENSE SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 222.101 Labor relations. ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Labor relations....

  14. 48 CFR 222.101 - Labor relations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OF DEFENSE SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 222.101 Labor relations. ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Labor relations....

  15. 48 CFR 222.101 - Labor relations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... OF DEFENSE SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 222.101 Labor relations. ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Labor relations....

  16. 48 CFR 222.101 - Labor relations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... OF DEFENSE SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 222.101 Labor relations. ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Labor relations....

  17. Method for Producing Non-Neoplastic, Three Dimensional, Mammalian Tissue and Cell Aggregates Under Microgravity Culture Conditions and the Products Produced Therefrom

    NASA Technical Reports Server (NTRS)

    Goodwin, Thomas J. (Inventor); Wolf, David A. (Inventor); Spaulding, Glenn F. (Inventor); Prewett, Tracey L. (Inventor)

    1996-01-01

    Normal mammalian tissue and the culturing process has been developed for the three groups of organ, structural, and blood tissue. The cells are grown in vitro under microgravity culture conditions and form three dimensional cells aggregates with normal cell function. The microgravity culture conditions may be microgravity or simulated microgravity created in a horizontal rotating wall culture vessel.

  18. Levobupivacaine for labor analgesia

    PubMed Central

    Attri, Joginder Pal; Makhni, Reena; Sethi, Savinder

    2016-01-01

    Background: Combined spinal-epidural analgesia has become the preferred technique for labor analgesia as it combines the benefits of both spinal analgesia and flexibility of epidural catheter. Study was carried out with the primary aim to compare levobupivacaine and ropivacaine with fentanyl in terms of onset and duration of sensory block and to know maternal and fetal outcome. Materials and Methods: In a prospective randomized double-blind study, 60 primipara of the American Society of Anesthesiologists health status Class I and II with singleton pregnancy in active stage of labor were randomly allocated into two groups of 30 each. Group A received 3 mg intrathecal levobupivacaine with 25 μg fentanyl followed by epidural top-ups of 14 ml of levobupivacaine 0.125% with fentanyl 30 μg whereas Group B received 4 mg intrathecal ropivacaine with 25 μg fentanyl followed by epidural top-ups of 14 ml of ropivacaine 0.2% with fentanyl 30 μg. Patients were monitored for sensory and motor block characteristics, hemodynamics, maternal and fetal outcome, side effects, and complications. These characteristics were analyzed using the “Chi-square tests” and “unpaired t-test.” Results: Onset of analgesia was rapid in Group A (4.72 ± 0.54 min) as compared to Group B (5.58 ± 0.49 min). Duration of analgesia was also prolonged in Group A (117.00 ± 11.86 min) as compared to Group B (90.17 ± 8.85 min). Patients remained hemodynamically stable and side effects, and complications were comparable in both groups. Conclusion: Levobupivacaine with fentanyl leads to early onset and prolonged duration of analgesia as compared to ropivacaine with fentanyl during labor analgesia. PMID:27746539

  19. A proposal to demonstrate production of salad crops in the space station mockup facility with particular attention to space, energy, and labor constraints

    NASA Technical Reports Server (NTRS)

    Brooks, Carolyn A.; Sharma, Govind C.; Beyl, Caula A.

    1990-01-01

    A desire for fresh vegetables for consumption during long term space missions has been foreseen. To meet this need in a microgravity environment within the limited space and energy available on Space Station requires highly productive vegetable cultivars of short stature to optimize vegetable production per volume available. Special water and nutrient delivery systems must also be utilized. As a first step towards fresh vegetable production in the microgravity of Space Station, several soil-less capillary action media were evaluated for the ability to support growth of two root crops (radish and carrot) which are under consideration for inclusion in a semi-automated system for production of salad vegetables in a microgravity environment (Salad Machine). In addition, productivity of different cultivars of radish was evaluated as well as the effect of planting density and cultivar on carrot production and size. Red Prince radish was more productive than Cherry Belle and grew best on Jiffy Mix Plus. During greenhouse studies, vermiculite and rock wool supported radish growth to a lesser degree than Jiffy Mix Plus but more than Cellular Rooting Sponge. Comparison of three carrot cultivars (Planet, Short n Sweet, and Goldinhart) and three planting densities revealed that Short n Sweet planted at 25.6 sq cm/plant had the greatest root fresh weight per pot, the shortest mean top length, and intermediate values of root length and top fresh weight per pot. Red Prince radish and Short n Sweet carrot showed potential as productive cultivars for use in a Salad Machine. Results of experiments with solid capillary action media were disappointing. Further research must be done to identify a solid style capillary action media which can productively support growth of root crops such as carrot and radish.

  20. 29 CFR 401.9 - Labor organization.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 2 2011-07-01 2011-07-01 false Labor organization. 401.9 Section 401.9 Labor Regulations... MEANING OF TERMS USED IN THIS SUBCHAPTER § 401.9 Labor organization. Labor organization means a labor organization engaged in an industry affecting commerce and includes any organization of any kind, any...

  1. 29 CFR 401.9 - Labor organization.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 2 2013-07-01 2013-07-01 false Labor organization. 401.9 Section 401.9 Labor Regulations... MEANING OF TERMS USED IN THIS SUBCHAPTER § 401.9 Labor organization. Labor organization means a labor organization engaged in an industry affecting commerce and includes any organization of any kind, any...

  2. 29 CFR 401.9 - Labor organization.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 2 2014-07-01 2014-07-01 false Labor organization. 401.9 Section 401.9 Labor Regulations... MEANING OF TERMS USED IN THIS SUBCHAPTER § 401.9 Labor organization. Labor organization means a labor organization engaged in an industry affecting commerce and includes any organization of any kind, any...

  3. 29 CFR 401.9 - Labor organization.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 2 2012-07-01 2012-07-01 false Labor organization. 401.9 Section 401.9 Labor Regulations... MEANING OF TERMS USED IN THIS SUBCHAPTER § 401.9 Labor organization. Labor organization means a labor organization engaged in an industry affecting commerce and includes any organization of any kind, any...

  4. 29 CFR 401.9 - Labor organization.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Labor organization. 401.9 Section 401.9 Labor Regulations... MEANING OF TERMS USED IN THIS SUBCHAPTER § 401.9 Labor organization. Labor organization means a labor organization engaged in an industry affecting commerce and includes any organization of any kind, any...

  5. Oil-Price Shocks: Beyond Standard Aggregate Demand/Aggregate Supply Analysis.

    ERIC Educational Resources Information Center

    Elwood, S. Kirk

    2001-01-01

    Explores the problems of portraying oil-price shocks using the aggregate demand/aggregate supply model. Presents a simple modification of the model that differentiates between production and absorption of goods, which enables it to better reflect the effects of oil-price shocks on open economies. (RLH)

  6. Succession of Protists on Estuarine Aggregates.

    PubMed

    Wörner; Zimmerman-Timm; Kausch

    2000-08-01

    Colonization by and succession of bacteria and bacterivorous protists on laboratory-made aggregates were determined over a period of 14 days during winter and spring in 1997. Aggregates were generated from natural water from the limnetic zone of the Elbe Estuary using a tilting tube roller system. Within 1 h after the beginning of the experiments, macroaggregates started to form. Aggregates reached a maximum size of 1 mm with a tendency toward large sizes at the end of the experiment after the 10th day. On the first day, high bacterial densities of more than 10(9) cells ml(-1) were detected within the aggregates. The abundances of flagellates and ciliates within aggregates were also two or three orders of magnitude higher than in the surrounding water. Densities of aggregate associated organisms are comparable to those occuring in sediments. The first protistan colonizers on the aggregates were small heterotrophic flagellates, such as choanoflagellates and small euglenids. Later, beginning on the 4th day, small sarcodines and ciliates became abundant. The most abundant ciliates associated with aggregates were small species of the Hypotrichia, Cyrtophorida, and Hymenostomata. After 9 days, large omnivorous and carnivorous ciliates, such as large members of the Hypotrichia and the Pleurostomatida, occurred. In spring, large heterotrophic flagellates and amebae also appeared at this time. These findings indicated the existence of a succession of protists on newly formed aggregates and a microbial food net within the aggregates based on bacterial production. Additionally, most of the species observed during this study were adapted for living on surfaces. In natural environments they are more common in benthic than in pelagic environments. For them, aggregates are havens in the water column comparable to sediment communities.

  7. 20 CFR 404.1056 - Explanation of agricultural labor.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... agricultural labor. An example of this is the extraction of juices from fruits or vegetables. However, work in... horticultural product. For example, all apples are a commodity, while apples and oranges are two...

  8. 20 CFR 404.1056 - Explanation of agricultural labor.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... agricultural labor. An example of this is the extraction of juices from fruits or vegetables. However, work in... horticultural product. For example, all apples are a commodity, while apples and oranges are two...

  9. 20 CFR 404.1056 - Explanation of agricultural labor.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... agricultural labor. An example of this is the extraction of juices from fruits or vegetables. However, work in... horticultural product. For example, all apples are a commodity, while apples and oranges are two...

  10. 20 CFR 404.1056 - Explanation of agricultural labor.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... agricultural labor. An example of this is the extraction of juices from fruits or vegetables. However, work in... horticultural product. For example, all apples are a commodity, while apples and oranges are two...

  11. 20 CFR 404.1056 - Explanation of agricultural labor.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... agricultural labor. An example of this is the extraction of juices from fruits or vegetables. However, work in... horticultural product. For example, all apples are a commodity, while apples and oranges are two...

  12. Aggregations in Flatworms.

    ERIC Educational Resources Information Center

    Liffen, C. L.; Hunter, M.

    1980-01-01

    Described is a school project to investigate aggregations in flatworms which may be influenced by light intensity, temperature, and some form of chemical stimulus released by already aggregating flatworms. Such investigations could be adopted to suit many educational levels of science laboratory activities. (DS)

  13. The Tobacco Product Education and Health Protection Act. Report from the Committee on Labor and Human Resources (To Accompany S. 2795). Senate, 101st Congress, 2d Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Committee on Labor and Human Resources.

    This document contains a report written to accompany "The Tobacco Product Education and Health Protection Act" (S. 2795), which authorizes a new title XV of the Public Health Service Act to establish a program of information, education, and research regarding the hazards of tobacco use. A summary of the bill notes that: (1) Subtitle A of the new…

  14. Three Structural Determinants of Participation of Women in the Labor Force: A Cross-National Analysis.

    ERIC Educational Resources Information Center

    Gorin, Zeev

    A natural study was conducted to determine the effects of division of labor (level of socio-economic development), dependency, and mode of production on participation of women in the labor force. Participation of women in the labor force was operationalized by two indicators: (1) women as percentage of the total number of wage earners and salaried…

  15. Migrant labor supply in a booming non-renewable resource economy: Cure and transmission mechanism for de-industrialization?

    NASA Astrophysics Data System (ADS)

    Nulle, Grant Mark

    This paper challenges the determinism that booming resource economies suffer from de-industrialization, the "Dutch Disease". For several decades, economists have attempted to explain how a sudden surge in mineral and energy extraction affects an economy's output and employment from an aggregate and sectoral perspective. Economic theory shows that a "boom" in mineral and energy production is welfare enhancing to the economy experiencing it. However, the phenomenon also induces inter-sectoral adjustments among non-renewable resource (NRR), traditional traded, and non-traded industries that tend to crowd out traditional export sectors such as agriculture and manufacturing. In turn, this paper asks two fundamental questions: 1) Can the inter-sectoral adjustments wrought by a boom in NRR production be mitigated in the resource-abundant economy experiencing it; 2) Can the inter-sectoral adjustments be exported to a neighboring non-resource economy by movements in migrant labor supply? The theoretical model and empirical estimation approach presented in this paper introduces an endogenous migrant labor supply response to booms in NRR output to test the extent traditional tradable sectors shrink in the NRR-abundant economy during the boom and if such effects are exported to a neighboring jurisdiction. Using data at the U.S. county level, the empirical results show that booming economies experience positive and statistically significant rates of real income and traded sector job growth during the boom, attributable to the influx of migrant labor. By contrast, little evidence is found that non-booming counties adjacent to the booming counties experience declines in income or job growth because of labor supply outflows. Instead, the results suggest the larger the number of potential "donor" counties that can supply labor to the booming economies, the more likely the transmission of booming economy effects, namely evidence of de-industrialization, is diffused across all of the

  16. Aggregate and the environment

    USGS Publications Warehouse

    Langer, William H.; Drew, Lawrence J.; Sachs, J.S.

    2004-01-01

    This book is designed to help you understand our aggregate resources-their importance, where they come from, how they are processed for our use, the environmental concerns related to their mining and processing, how those concerns are addressed, and the policies and regulations designed to safeguard workers, neighbors, and the environment from the negative impacts of aggregate mining. We hope this understanding will help prepare you to be involved in decisions that need to be made-individually and as a society-to be good stewards of our aggregate resources and our living planet.

  17. Labor Comes into Its Own.

    ERIC Educational Resources Information Center

    Wehrle, Edmund F.

    1996-01-01

    Presents a concise and interesting overview of the rise and extension of labor activity during the New Deal. Labor took advantage of Roosevelt's pro-union policies to consolidate their power and forever transform the lives of working men and women. Discusses improvements in working conditions, wages, and benefits. (MJP)

  18. Migrant labor absorption in Malaysia.

    PubMed

    Nayagam, J

    1992-01-01

    The use of migrant workers to ease labor shortages caused by rapid industrialization in Malaysia during the twentieth century is examined. "This paper will focus on: (1) the extent, composition and distribution of migrant workers; (2) the labor shortage and absorption of migrant workers; and (3) the role of migrant workers in the government's economic restructuring process."

  19. Migrant labor absorption in Malaysia.

    PubMed

    Nayagam, J

    1992-01-01

    The use of migrant workers to ease labor shortages caused by rapid industrialization in Malaysia during the twentieth century is examined. "This paper will focus on: (1) the extent, composition and distribution of migrant workers; (2) the labor shortage and absorption of migrant workers; and (3) the role of migrant workers in the government's economic restructuring process." PMID:12285766

  20. Legal Intervention in Labor Arbitration

    ERIC Educational Resources Information Center

    Gullett, C. Ray

    1978-01-01

    From a private process between unions and management, labor arbitration has become a matter for federal arbitrators to decide. The article traces this development through various federal court cases and legislation, particularly unfair labor practice charges under Title VII of the Civil Rights Act. (MF)

  1. EPIDURAL ANALGESIA IN LABOR - CONTROVERSIES.

    PubMed

    Bilić, Nada; Djaković, Ivka; Kličan-Jaić, Katarina; Rudman, Senka Sabolović; Ivanec, Željko

    2015-09-01

    Labor pain is one of the most severe pains. Labor is a complex and individual process with varying maternal requesting analgesia. Labor analgesia must be safe and accompanied by minimal amount of unwanted consequences for both the mother and the child, as well as for the delivery procedure. Epidural analgesia is the treatment that best meets these demands. According to the American Congress of Obstetrics and Gynecology and American Society of Anesthesiologists, mother's demand is a reason enough for the introduction of epidural analgesia in labor, providing that no contraindications exist. The application of analgesics should not cease at the end of the second stage of labor, but it is recommended that lower concentration analgesics be then applied. Based on the latest studies, it can be claimed that epidural analgesia can be applied during the major part of the first and second stage of labor. According to previous investigations, there is no definitive conclusion about the incidence of instrumental delivery, duration of second stage of labor, time of epidural analgesia initiation, and long term outcomes for the newborn. Cooperation of obstetric and anesthesiology personnel, as well as appropriate technical equipment significantly decrease the need of instrumental completion of a delivery, as well as other complications encountered in the application of epidural analgesia. Our hospital offers 24/7 epidural analgesia service. The majority of pregnant women in our hospital were aware of the advantages of epidural analgesia for labor, however, only a small proportion of them used it, mainly because of inadequate level of information.

  2. Effects of tau domain-specific antibodies and intravenous immunoglobulin on tau aggregation and aggregate degradation.

    PubMed

    Esteves-Villanueva, Jose O; Trzeciakiewicz, Hanna; Loeffler, David A; Martić, Sanela

    2015-01-20

    Tau pathology, including neurofibrillary tangles, develops in Alzheimer's disease (AD). The aggregation and hyperphosphorylation of tau are potential therapeutic targets for AD. Administration of anti-tau antibodies reduces tau pathology in transgenic "tauopathy" mice; however, the optimal tau epitopes and conformations to target are unclear. Also unknown is whether intravenous immunoglobulin (IVIG) products, currently being evaluated in AD trials, exert effects on pathological tau. This study examined the effects of anti-tau antibodies targeting different tau epitopes and the IVIG Gammagard on tau aggregation and preformed tau aggregates. Tau aggregation was assessed by transmission electron microscopy and fluorescence spectroscopy, and the binding affinity of the anti-tau antibodies for tau was evaluated by enzyme-linked immunosorbent assays. Antibodies used were anti-tau 1-150 ("D-8"), anti-tau 259-266 ("Paired-262"), anti-tau 341-360 ("A-10"), and anti-tau 404-441 ("Tau-46"), which bind to tau's N-terminus, microtubule binding domain (MBD) repeat sequences R1 and R4, and the C-terminus, respectively. The antibodies Paired-262 and A-10, but not D-8 and Tau-46, reduced tau fibrillization and degraded preformed tau aggregates, whereas the IVIG reduced tau aggregation but did not alter preformed aggregates. The binding affinities of the antibodies for the epitope for which they were specific did not appear to be related to their effects on tau aggregation. These results confirm that antibody binding to tau's MBD repeat sequences may inhibit tau aggregation and indicate that such antibodies may also degrade preformed tau aggregates. In the presence of anti-tau antibodies, the resulting tau morphologies were antigen-dependent. The results also suggested the possibility of different pathways regulating antibody-mediated inhibition of tau aggregation and antibody-mediated degradation of preformed tau aggregates. PMID:25545358

  3. Economic Dislocation and Worker Adjustment Assistance Act. Joint Hearings on S. 538 to Implement the Recommendations of the Secretary of Labor's Task Force on Economic Adjustment and Worker Dislocation, and for Other Purposes, before the Subcommittee on Labor and the Subcommittee on Employment and Productivity of the Committee on Labor and Human Resources. United States Senate, One-Hundredth Congress, First Session (March 10 and 26, 1987).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Committee on Labor and Human Resources.

    This congressional report on Senate Bill 538 contains the testimony that was given at joint hearings to debate the passage of the Economic Dislocation and Worker Adjustment Assistance Act. This act, which is based primarily on the recommendations of U.S. Secretary of Labor Brock's blue ribbon task force: (1) creates displaced worker units at the…

  4. The Nation's top 25 construction aggregates producers

    USGS Publications Warehouse

    Willett, Jason Christopher

    2013-01-01

    U.S. production of construction aggregates in 2011 was 2.17 billion short tons, valued at $17.2 billion, free on board (f.o.b.) at plant. Construction aggregates production decreased by 37 percent, and the associated value decreased by 25 percent, compared with the record highs reported in 2006. In 2011, construction aggregates production increased for the first time since 2006, owing to a very slight increase in the production of both construction sand and gravel and crushed stone. The average unit value, which is the f.o.b. at plant price of a ton of material, increased slightly, but is still less than the average unit value of two years prior.

  5. A proposal to demonstrate production of salad crops in the Space Station Mockup Facility with particular attention to space, energy, and labor constraints

    NASA Technical Reports Server (NTRS)

    Brooks, Carolyn A.

    1992-01-01

    The Salad Machine Research has continued to be a two path effort with the research at Marshall Space Flight Center (MSFC) focusing on the design, construction, and operation of a semiautomated system (Salad Machine) for the production of salad vegetables within a standard rack. Boeing Corporation in cooperation with NASA MSFC constructed a four drawer Salad Machine which was occasionally placed within the Space Station Freedom Mockup facility for view by selected visitors. Final outfitting of the Salad Machine is awaiting the arrival of parts for the nutrient delivery system. Research at the Alabama A&M facilities focused on compatibility of radish and lettuce plants when grown on the same nutrient solution. Lettuce fresh weight shoot yield was significantly enhanced when lettuce plants were grown on nutrient solution which was shared with radish. Radish tuber production was not significantly affected although there was a trend for radish from shared solutions to be heavier than those grown on separate nutrient solutions. The effect of sharing nutrient solutions on carbohydrate partitioning reflected the effect of sharing solution on fresh weight yield. Lettuce shoot dry weight was significantly greater for plants from shared solutions than from separate. There was no significant effect on sharing nutrient solution on radish tuber dry weight. Partitioning of nitrogen, calcium, magnesium, and potassium was not affected by sharing, there was, however, a disproportionate amount of potassium in the tissues, suggesting luxury consumption of potassium in all plants and tissues. It is concluded that lettuce plants benefit from sharing nutrient solution with radish and that radish is not harmed.

  6. Protein Colloidal Aggregation Project

    NASA Technical Reports Server (NTRS)

    Oliva-Buisson, Yvette J. (Compiler)

    2014-01-01

    To investigate the pathways and kinetics of protein aggregation to allow accurate predictive modeling of the process and evaluation of potential inhibitors to prevalent diseases including cataract formation, chronic traumatic encephalopathy, Alzheimer's Disease, Parkinson's Disease and others.

  7. Recycling of MSWI fly ash by means of cementitious double step cold bonding pelletization: Technological assessment for the production of lightweight artificial aggregates.

    PubMed

    Colangelo, Francesco; Messina, Francesco; Cioffi, Raffaele

    2015-12-15

    In this work, an extensive study on the recycling of municipal solid waste incinerator fly ash by means of cold bonding pelletization is presented. The ash comes from an incineration plant equipped with rotary and stoker furnaces, in which municipal, hospital and industrial wastes are treated. Fly ash from waste incineration is classified as hazardous and cannot be utilized or even landfilled without prior treatment. The pelletization process uses cement, lime and coal fly ash as components of the binding systems. This process has been applied to several mixes in which the ash content has been varied from 50% (wt.%) up to a maximum of 70%. An innovative additional pelletization step with only cementitious binder has been performed in order to achieve satisfactory immobilization levels. The obtained lightweight porous aggregates are mostly suitable for recovery in the field of building materials with enhanced sustainability properties. Density, water absorption and crushing strength ranged from 1000 to 1600 kg/m(3), 7 to 16% and 1.3 to 6.2 MPa, respectively, and the second pelletization step increased stabilization efficiency. The feasibility of the process has been analyzed by testing also concrete specimens containing the artificial aggregates, resulting in lightweight concrete of average performance. PMID:26124064

  8. Recycling of MSWI fly ash by means of cementitious double step cold bonding pelletization: Technological assessment for the production of lightweight artificial aggregates.

    PubMed

    Colangelo, Francesco; Messina, Francesco; Cioffi, Raffaele

    2015-12-15

    In this work, an extensive study on the recycling of municipal solid waste incinerator fly ash by means of cold bonding pelletization is presented. The ash comes from an incineration plant equipped with rotary and stoker furnaces, in which municipal, hospital and industrial wastes are treated. Fly ash from waste incineration is classified as hazardous and cannot be utilized or even landfilled without prior treatment. The pelletization process uses cement, lime and coal fly ash as components of the binding systems. This process has been applied to several mixes in which the ash content has been varied from 50% (wt.%) up to a maximum of 70%. An innovative additional pelletization step with only cementitious binder has been performed in order to achieve satisfactory immobilization levels. The obtained lightweight porous aggregates are mostly suitable for recovery in the field of building materials with enhanced sustainability properties. Density, water absorption and crushing strength ranged from 1000 to 1600 kg/m(3), 7 to 16% and 1.3 to 6.2 MPa, respectively, and the second pelletization step increased stabilization efficiency. The feasibility of the process has been analyzed by testing also concrete specimens containing the artificial aggregates, resulting in lightweight concrete of average performance.

  9. Cell aggregation and sedimentation.

    PubMed

    Davis, R H

    1995-01-01

    The aggregation of cells into clumps or flocs has been exploited for decades in such applications as biological wastewater treatment, beer brewing, antibiotic fermentation, and enhanced sedimentation to aid in cell recovery or retention. More recent research has included the use of cell aggregation and sedimentation to selectively separate subpopulations of cells. Potential biotechnological applications include overcoming contamination, maintaining plasmid-bearing cells in continuous fermentors, and selectively removing nonviable hybridoma cells from perfusion cultures.

  10. Refining aggregate exposure: example using parabens.

    PubMed

    Cowan-Ellsberry, Christina E; Robison, Steven H

    2009-12-01

    The need to understand and estimate quantitatively the aggregate exposure to ingredients used broadly in a variety of product types continues to grow. Currently aggregate exposure is most commonly estimated by using a very simplistic approach of adding or summing the exposures from all the individual product types in which the chemical is used. However, the more broadly the ingredient is used in related consumer products, the more likely this summation will result in an unrealistic estimate of exposure because individuals in the population vary in their patterns of product use including co-use and non-use. Furthermore the ingredient may not be used in all products of a given type. An approach is described for refining this aggregate exposure using data on (1) co-use and non-use patterns of product use, (2) extent of products in which the ingredient is used and (3) dermal penetration and metabolism. This approach and the relative refinement in the aggregate exposure from incorporating these data is illustrated using methyl, n-propyl, n-butyl and ethyl parabens, the most widely used preservative system in personal care and cosmetic products. When these refining factors were used, the aggregate exposure compared to the simple addition approach was reduced by 51%, 58%, 90% and 92% for methyl, n-propyl, n-butyl and ethyl parabens, respectively. Since biomonitoring integrates all sources and routes of exposure, the estimates using this approach were compared to available paraben biomonitoring data. Comparison to the 95th percentile of these data showed that these refined estimates were still conservative by factors of 2-92. All of our refined estimates of aggregate exposure are less than the ADI of 10mg/kg/day for parabens.

  11. Child Labor Requirements in Agriculture under the Fair Labor Standards Act. Child Labor Bulletin No. 102.

    ERIC Educational Resources Information Center

    Employment Standards Administration (DOL), Washington, DC. Wage and Hour Div.

    This booklet is a guide to the provisions of the Fair Labor Standards Act (also known as the Wage-Hour Law) which apply to minors employed in agriculture. The content is as follows: coverage of the child labor provisions regarding agricultural employment, minimum age standards for employment in agriculture, school hours and employment in…

  12. A Select Bibliography of Books on Labor Issues.

    ERIC Educational Resources Information Center

    American Federation of Labor and Congress of Industrial Organizations, Washington, DC.

    This annotated bibliography of 90 books on labor issues presents selections in the following areas: labor history, biographies, contemporary issues, labor economics and labor relations, labor law, labor unions, women and work, and reference books. (DB)

  13. Urban Scaling and the Production Function for Cities

    PubMed Central

    Lobo, José; Bettencourt, Luís M. A.; Strumsky, Deborah; West, Geoffrey B.

    2013-01-01

    The factors that account for the differences in the economic productivity of urban areas have remained difficult to measure and identify unambiguously. Here we show that a microscopic derivation of urban scaling relations for economic quantities vs. population, obtained from the consideration of social and infrastructural properties common to all cities, implies an effective model of economic output in the form of a Cobb-Douglas type production function. As a result we derive a new expression for the Total Factor Productivity (TFP) of urban areas, which is the standard measure of economic productivity per unit of aggregate production factors (labor and capital). Using these results we empirically demonstrate that there is a systematic dependence of urban productivity on city population size, resulting from the mismatch between the size dependence of wages and labor, so that in contemporary US cities productivity increases by about 11% with each doubling of their population. Moreover, deviations from the average scale dependence of economic output, capturing the effect of local factors, including history and other local contingencies, also manifest surprising regularities. Although, productivity is maximized by the combination of high wages and low labor input, high productivity cities show invariably high wages and high levels of employment relative to their size expectation. Conversely, low productivity cities show both low wages and employment. These results shed new light on the microscopic processes that underlie urban economic productivity, explain the emergence of effective aggregate urban economic output models in terms of labor and capital inputs and may inform the development of economic theory related to growth. PMID:23544042

  14. Mineralogy and petrography of amoeboid olivine aggregates from the reduced CV3 chondrites Efremovka, Leoville and Vigarano: Products of nebular condensation, accretion and annealing

    NASA Astrophysics Data System (ADS)

    Komatsu, Mutsumi; Krot, Alexander N.; Petaev, Mikhail I.; Ulyanov, Alexander A.; Keil, Klaus; Miyamoto, Masamichi

    2001-05-01

    Amoeboid olivine aggregates (AOAs) from the reduced CV chondrites Efremovka, Leoville and Vigarano are irregularly-shaped objects, up to 5 mm in size, composed of forsteritic olivine (Fa<10) and a refractory, Ca,Al-rich component. The AOAs are depleted in moderately volatile elements (Mn, Cr, Na, K), Fe,Ni-metal and sulfides and contain no low-Ca pyroxene. The refractory component consists of fine-grained Ca,Al-rich inclusions (CAIs) composed of Al-diopside, anorthite (An100), and magnesium-rich spinel (~1 wt% FeO) or fine-grained intergrowths of these minerals; secondary nepheline and sodalite are very minor. This indicates that AOAs from the reduced CV chondrites are more pristine than those from the oxidized CV chondrites Allende and Mokoia. Although AOAs from the reduced CV chondrites show evidence for high temperature nebular annealing (e.g., forsterite grain boundaries form 120 deg triple junctions) and possibly a minor degree of melting of Al-diopside-anorthite materials, none of the AOAs studied appear to have experienced extensive (>50%) melting. We infer that AOAs are aggregates of high temperature nebular condensates, which formed in CAI-forming regions, and that they were absent from chondrule-forming regions at the time of chondrule formation. The absence of low-Ca pyroxene and depletion in moderately volatile elements (Mn, Cr, Na, K) suggest that AOAs were either removed from CAI-forming regions prior to condensation of these elements and low-Ca pyroxene or gas-solid condensation of low-Ca-pyroxene was kinetically inhibited.

  15. Fibronectin Aggregation and Assembly

    PubMed Central

    Ohashi, Tomoo; Erickson, Harold P.

    2011-01-01

    The mechanism of fibronectin (FN) assembly and the self-association sites are still unclear and contradictory, although the N-terminal 70-kDa region (I1–9) is commonly accepted as one of the assembly sites. We previously found that I1–9 binds to superfibronectin, which is an artificial FN aggregate induced by anastellin. In the present study, we found that I1–9 bound to the aggregate formed by anastellin and a small FN fragment, III1–2. An engineered disulfide bond in III2, which stabilizes folding, inhibited aggregation, but a disulfide bond in III1 did not. A gelatin precipitation assay showed that I1–9 did not interact with anastellin, III1, III2, III1–2, or several III1–2 mutants including III1–2KADA. (In contrast to previous studies, we found that the III1–2KADA mutant was identical in conformation to wild-type III1–2.) Because I1–9 only bound to the aggregate and the unfolding of III2 played a role in aggregation, we generated a III2 domain that was destabilized by deletion of the G strand. This mutant bound I1–9 as shown by the gelatin precipitation assay and fluorescence resonance energy transfer analysis, and it inhibited FN matrix assembly when added to cell culture. Next, we introduced disulfide mutations into full-length FN. Three disulfide locks in III2, III3, and III11 were required to dramatically reduce anastellin-induced aggregation. When we tested the disulfide mutants in cell culture, only the disulfide bond in III2 reduced the FN matrix. These results suggest that the unfolding of III2 is one of the key factors for FN aggregation and assembly. PMID:21949131

  16. Labor Shortage: Menace or Mirage?

    ERIC Educational Resources Information Center

    Sargent, Jon

    1988-01-01

    There are many uncertainties about the magnitude and nature of labor shortages. Data needed to identify and quantify shortages are not available from national statistical offices so most of what is known comes from employer reports. (JOW)

  17. Labor Functions of Illegal Aliens

    ERIC Educational Resources Information Center

    Portes, Alejandro

    1977-01-01

    Concludes that to the extent that collective defenselessness of workers exists anywhere, movements like illegal immigration, the self-transportation of cheap labor toward the places where needed, are bound to continue. (Author/AM)

  18. Survey of Labor Economics Textbooks.

    ERIC Educational Resources Information Center

    Maxwell, Nan L.

    1985-01-01

    Labor economics textbooks for use with college students were surveyed. Information concerning intended audience, content, and teaching aids is provided for each text. Criteria used in evaluating the texts is provided. (RM)

  19. Strength of masonry blocks made with recycled concrete aggregates

    NASA Astrophysics Data System (ADS)

    Matar, Pierre; Dalati, Rouba El

    The idea of recycling concrete of demolished buildings aims at preserving the environment. Indeed, the reuse of concrete as aggregate in new concrete mixes helped to reduce the expenses related to construction and demolition (C&D) waste management and, especially, to protect the environment by reducing the development rate of new quarries. This paper presents the results of an experimental study conducted on masonry blocks containing aggregates resulting from concrete recycling. The purpose of this study is to investigate the effect of recycled aggregates on compressive strength of concrete blocks. Tests were performed on series of concrete blocks: five series each made of different proportions of recycled aggregates, and one series of reference blocks exclusively composed of natural aggregates. Tests showed that using recycled aggregates with addition of cement allows the production of concrete blocks with compressive strengths comparable to those obtained on concrete blocks made exclusively of natural aggregates.

  20. Reusing recycled aggregates in structural concrete

    NASA Astrophysics Data System (ADS)

    Kou, Shicong

    results, a number of recommendations were made on how to optimize the use of recycled aggregates for structural concrete production. The results demonstrate that one of the practical ways to utilize a higher percentage of recycled aggregates in concrete is "precasting" with the use of fly ash and an initial steam curing stage immediately after casting.

  1. Generation of Soluble Advanced Glycation End Products Receptor (sRAGE)-Binding Ligands during Extensive Heat Treatment of Whey Protein/Lactose Mixtures Is Dependent on Glycation and Aggregation.

    PubMed

    Liu, Fahui; Teodorowicz, Małgorzata; Wichers, Harry J; van Boekel, Martinus A J S; Hettinga, Kasper A

    2016-08-24

    Heating of protein- and sugar-containing materials is considered the primary factor affecting the formation of advanced glycation end products (AGEs). This study aimed to investigate the influence of heating conditions, digestion, and aggregation on the binding capacity of AGEs to the soluble AGE receptor (sRAGE). Samples consisting of mixtures of whey protein and lactose were heated at 130 °C. An in vitro infant digestion model was used to study the influence of heat treatment on the digestibility of whey proteins. The amount of sRAGE-binding ligands before and after digestion was measured by an ELISA-based sRAGE-binding assay. Water activity did not significantly affect the extent of digestibility of whey proteins dry heated at pH 5 (ranging from 3.3 ± 0.2 to 3.6 ± 0.1% for gastric digestion and from 53.5 ± 1.5 to 64.7 ± 1.1% for duodenal digestion), but there were differences in cleavage patterns of peptides among the samples heated at different pH values. Formation of sRAGE-binding ligands depended on the formation of aggregates and was limited in the samples heated at pH 5. Moreover, the sRAGE-binding activity of digested sample was changed by protease degradation and correlated with the digestibility of samples. In conclusion, generation of sRAGE-binding ligands during extensive heat treatment of whey protein/lactose mixtures is limited in acidic heating condition and dependent on glycation and aggregation. PMID:27460534

  2. New Labor Pain Treatment Options.

    PubMed

    Koyyalamudi, Veerandra; Sidhu, Gurleen; Cornett, Elyse M; Nguyen, Viet; Labrie-Brown, Carmen; Fox, Charles J; Kaye, Alan D

    2016-02-01

    Presently, the gold standard for pain control in laboring patients is neuraxial blockade, which includes a spinal, epidural, or a combined spinal-epidural technique. In conjunction with neuraxial blockade or by itself, some of the other agents employed related to labor pain include opioids, non-opioids, nitrous oxide, patient-controlled analgesia (PCA), and distraction therapy. Alternative treatments include acupuncture, hypnotism, yoga, exercise during pregnancy, hydrotherapy, transcutaneous electronic nerve stimulation, massage, and relaxation techniques. This review will focus on current updates and recent trends in labor pain management. Neuraxial management, pharmacotherapy, and newer alternative methods to mitigate labor pain are reviewed. Newer techniques in epidural analgesia include the dural puncture epidural technique, which needs further evaluation. There are limited published data on the use of acupuncture, hypnotism, yoga, exercise during pregnancy, hydrotherapy, transcutaneous electronic nerve stimulation, massage, and relaxation techniques in the alleviation of labor pain. These alternative therapies maybe considered as an adjuvant as the analgesic efficiency is inferior to that provided by typical standard pharmacotherapy. Future studies are warranted to evaluate the role of immersion virtual reality in alleviating labor pain.

  3. New Labor Pain Treatment Options.

    PubMed

    Koyyalamudi, Veerandra; Sidhu, Gurleen; Cornett, Elyse M; Nguyen, Viet; Labrie-Brown, Carmen; Fox, Charles J; Kaye, Alan D

    2016-02-01

    Presently, the gold standard for pain control in laboring patients is neuraxial blockade, which includes a spinal, epidural, or a combined spinal-epidural technique. In conjunction with neuraxial blockade or by itself, some of the other agents employed related to labor pain include opioids, non-opioids, nitrous oxide, patient-controlled analgesia (PCA), and distraction therapy. Alternative treatments include acupuncture, hypnotism, yoga, exercise during pregnancy, hydrotherapy, transcutaneous electronic nerve stimulation, massage, and relaxation techniques. This review will focus on current updates and recent trends in labor pain management. Neuraxial management, pharmacotherapy, and newer alternative methods to mitigate labor pain are reviewed. Newer techniques in epidural analgesia include the dural puncture epidural technique, which needs further evaluation. There are limited published data on the use of acupuncture, hypnotism, yoga, exercise during pregnancy, hydrotherapy, transcutaneous electronic nerve stimulation, massage, and relaxation techniques in the alleviation of labor pain. These alternative therapies maybe considered as an adjuvant as the analgesic efficiency is inferior to that provided by typical standard pharmacotherapy. Future studies are warranted to evaluate the role of immersion virtual reality in alleviating labor pain. PMID:26780039

  4. Technology meets aggregate

    SciTech Connect

    Wilson, C.; Swan, C.

    2007-07-01

    New technology carried out at Tufts University and the University of Massachusetts on synthetic lightweight aggregate has created material from various qualities of fly ash from coal-fired power plants for use in different engineered applications. In pilot scale manufacturing tests an 'SLA' containing 80% fly ash and 20% mixed plastic waste from packaging was produced by 'dry blending' mixed plastic with high carbon fly ash. A trial run was completed to produce concrete masonry unit (CMU) blocks at a full-scale facility. It has been shown that SLA can be used as a partial substitution of a traditional stone aggregate in hot asphalt mix. 1 fig., 2 photos.

  5. Why Should We Care about Child Labor? The Education, Labor Market, and Health Consequences of Child Labor

    ERIC Educational Resources Information Center

    Beegle, Kathleen; Dehejia, Rajeev; Gatti, Roberta

    2009-01-01

    Despite the extensive literature on the determinants of child labor, the evidence on the consequences of child labor on outcomes such as education, labor, and health is limited. We evaluate the causal effect of child labor participation among children in school on these outcomes using panel data from Vietnam and an instrumental variables strategy.…

  6. LPS ligand and culture additives improve production of monomeric MD-1 and 2 in Pichia pastoris by decreasing aggregation and intermolecular disulfide bonding.

    PubMed

    Mengwasser, Kristen E; Bryant, Clare E; Gay, Nick J; Gangloff, Monique

    2011-04-01

    Myeloid differentiation proteins MD-1 and MD-2 have both been shown to form a heterogeneous collection of oligomers when expressed in absence of their respective receptor, RP105 and TLR4. The biological relevance of these oligomers is not clear. Only monomeric proteins have been found to be active and able to trigger an immune response to endotoxin by modulating the TLR4 pathway. In this study, we produced variants of MD-1 and MD-2 in Pichia pastoris. To minimize the time and expense of initial expression tests, small-scale cultures have been set up to allow the rapid identification of the highest expressing clone and the optimal expression conditions. The expression vectors used, the site of linearization and the locus of integration affected the yield of transformation. Next we screened culture additives and found that they significantly increased the fraction of monomeric proteins secreted in the culture medium (up to 15% of the total MD protein produced). We confirmed their presence by size-exclusion chromatography. Optimal anti-aggregation agents were protein-dependent except for LPS that presented stabilizing effects for all MD proteins. Contrary to previous reports, this study suggests that MD-1 can bind to LPS. PMID:21130168

  7. Microstructural characterization of concrete prepared with recycled aggregates.

    PubMed

    Guedes, Mafalda; Evangelista, Luís; de Brito, Jorge; Ferro, Alberto C

    2013-10-01

    Several authors have reported the workability, mechanical properties, and durability of concrete produced with construction waste replacing the natural aggregate. However, a systematic microstructural characterization of recycled aggregate concrete has not been reported. This work studies the use of fine recycled aggregate to replace fine natural aggregate in the production of concrete and reports the resulting microstructures. The used raw materials were natural aggregate, recycled aggregate obtained from a standard concrete, and Portland cement. The substitution extent was 0, 10, 50, and 100 vol%; hydration was stopped at 9, 24, and 96 h and 28 days. Microscopy was focused on the cement/aggregate interfacial transition zone, enlightening the effect of incorporating recycled aggregate on the formation and morphology of the different concrete hydration products. The results show that concretes with recycled aggregates exhibit typical microstructural features of the transition zone in normal strength concrete. Although overall porosity increases with increasing replacement, the interfacial bond is apparently stronger when recycled aggregates are used. An addition of 10 vol% results in a decrease in porosity at the interface with a corresponding increase of the material hardness. This provides an opportunity for development of increased strength Portland cement concretes using controlled amounts of concrete waste. PMID:23673273

  8. Microstructural characterization of concrete prepared with recycled aggregates.

    PubMed

    Guedes, Mafalda; Evangelista, Luís; de Brito, Jorge; Ferro, Alberto C

    2013-10-01

    Several authors have reported the workability, mechanical properties, and durability of concrete produced with construction waste replacing the natural aggregate. However, a systematic microstructural characterization of recycled aggregate concrete has not been reported. This work studies the use of fine recycled aggregate to replace fine natural aggregate in the production of concrete and reports the resulting microstructures. The used raw materials were natural aggregate, recycled aggregate obtained from a standard concrete, and Portland cement. The substitution extent was 0, 10, 50, and 100 vol%; hydration was stopped at 9, 24, and 96 h and 28 days. Microscopy was focused on the cement/aggregate interfacial transition zone, enlightening the effect of incorporating recycled aggregate on the formation and morphology of the different concrete hydration products. The results show that concretes with recycled aggregates exhibit typical microstructural features of the transition zone in normal strength concrete. Although overall porosity increases with increasing replacement, the interfacial bond is apparently stronger when recycled aggregates are used. An addition of 10 vol% results in a decrease in porosity at the interface with a corresponding increase of the material hardness. This provides an opportunity for development of increased strength Portland cement concretes using controlled amounts of concrete waste.

  9. The PHD labor market: A primer

    SciTech Connect

    Baker, J.G.

    1994-08-01

    There are currently two major issues regarding Ph.D. scientists that are cause for concern. The first issue, adequacy of Ph.D. supply, follows from a general concern among educators and science policy specialists that the 1990s and beyond will usher in an era of general shortages for Ph D. scientists. These expected shortages are thought to be the result of: (1) Inadequate Ph.D. supply response to demand changes. Ph.D. supply has been hampered by declining federal support and increasing time to complete the doctorate. The long gestation period to produce a Ph.D. implies relatively unresponsive labor supply. (2) Increasing industrial demand in such areas as electronics, environmental control and biotechnology. (3) Increasing academic demand after several years of decline (the ``baby boom echo``). In addition, replacement of aging faculty is expected to accelerate in the next decade. The second major issue regarding Ph.D. scientists concerns a dismal current labor market. Levels of federal R&D funding growth, particularly for young investigators, have been declining. Retrenchment of public and private universities facing budget problems has delayed (or cancelled) faculty hiring. There is currently widespread alarm and concern in the US science establishment about the perceived decline in the availability of research funding and university faculty positions to sustain the existing stock of scientists in productive activities and to continue to ``send the message`` to the best young minds that science has room for them. The first issue implies a future shortage of scientists, the second issue implies a current surplus. The purpose of this paper is to provide a brief overview of Ph.D. labor market models and summarize the existing knowledge on the labor market for Ph.D. scientists and engineers.

  10. Concrete Waste Recycling Process for High Quality Aggregate

    SciTech Connect

    Ishikura, Takeshi; Fujii, Shin-ichi

    2008-01-15

    Large amount of concrete waste generates during nuclear power plant (NPP) dismantling. Non-contaminated concrete waste is assumed to be disposed in a landfill site, but that will not be the solution especially in the future, because of decreasing tendency of the site availability and natural resources. Concerning concrete recycling, demand for roadbeds and backfill tends to be less than the amount of dismantled concrete generated in a single rural site, and conventional recycled aggregate is limited of its use to non-structural concrete, because of its inferior quality to ordinary natural aggregate. Therefore, it is vital to develop high quality recycled aggregate for general uses of dismantled concrete. If recycled aggregate is available for high structural concrete, the dismantling concrete is recyclable as aggregate for industry including nuclear field. Authors developed techniques on high quality aggregate reclamation for large amount of concrete generated during NPP decommissioning. Concrete of NPP buildings has good features for recycling aggregate; large quantity of high quality aggregate from same origin, record keeping of the aggregate origin, and little impurities in dismantled concrete such as wood and plastics. The target of recycled aggregate in this development is to meet the quality criteria for NPP concrete as prescribed in JASS 5N 'Specification for Nuclear Power Facility Reinforced Concrete' and JASS 5 'Specification for Reinforced Concrete Work'. The target of recycled aggregate concrete is to be comparable performance with ordinary aggregate concrete. The high quality recycled aggregate production techniques are assumed to apply for recycling for large amount of non-contaminated concrete. These techniques can also be applied for slightly contaminated concrete dismantled from radiological control area (RCA), together with free release survey. In conclusion: a technology on dismantled concrete recycling for high quality aggregate was developed

  11. Aggregates, broccoli and cauliflower

    NASA Astrophysics Data System (ADS)

    Grey, Francois; Kjems, Jørgen K.

    1989-09-01

    Naturally grown structures with fractal characters like broccoli and cauliflower are discussed and compared with DLA-type aggregates. It is suggested that the branching density can be used to characterize the growth process and an experimental method to determine this parameter is proposed.

  12. Transforming labor-management practices through real-time analytics.

    PubMed

    Nippert, Kathye Habig; Graves, Brian

    2012-06-01

    Catholic Health Partners (CHP) decentralized productivity management, giving its regional executives greater control over their productivity tools and data. CHP retained centralized management of its benchmarking and analytics and created an enterprise database with standardized information. CHP's stakeholders shared accountability and accepted greater responsibility for labor-management decisions.

  13. 24 CFR 585.313 - Labor standards.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) Laborers and mechanics other than Youthbuild Trainees. (1) All laborers and mechanics (other than... such laborers and mechanics on assisted housing shall be subject to the provisions of the Contract Work... standards apply to laborers and mechanics other than Youthbuild trainees to the extent required by the...

  14. 24 CFR 585.313 - Labor standards.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) Laborers and mechanics other than Youthbuild Trainees. (1) All laborers and mechanics (other than... such laborers and mechanics on assisted housing shall be subject to the provisions of the Contract Work... standards apply to laborers and mechanics other than Youthbuild trainees to the extent required by the...

  15. 24 CFR 585.313 - Labor standards.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) Laborers and mechanics other than Youthbuild Trainees. (1) All laborers and mechanics (other than... such laborers and mechanics on assisted housing shall be subject to the provisions of the Contract Work... standards apply to laborers and mechanics other than Youthbuild trainees to the extent required by the...

  16. 48 CFR 2822.101 - Labor relations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Labor relations. 2822.101 Section 2822.101 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 2822.101 Labor relations....

  17. 48 CFR 2822.101 - Labor relations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Labor relations. 2822.101 Section 2822.101 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 2822.101 Labor relations....

  18. 48 CFR 22.101 - Labor relations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Labor relations. 22.101 Section 22.101 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 22.101 Labor relations....

  19. 24 CFR 585.313 - Labor standards.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Laborers and mechanics other than Youthbuild Trainees. (1) All laborers and mechanics (other than... such laborers and mechanics on assisted housing shall be subject to the provisions of the Contract Work... standards apply to laborers and mechanics other than Youthbuild trainees to the extent required by the...

  20. 48 CFR 22.101 - Labor relations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Labor relations. 22.101 Section 22.101 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 22.101 Labor relations....

  1. 48 CFR 1222.101 - Labor relations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Labor relations. 1222.101 Section 1222.101 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 1222.101 Labor relations....

  2. 48 CFR 1322.101 - Labor relations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Labor relations. 1322.101 Section 1322.101 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 1322.101 Labor relations....

  3. 48 CFR 1322.101 - Labor relations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Labor relations. 1322.101 Section 1322.101 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 1322.101 Labor relations....

  4. 48 CFR 1422.101 - Labor relations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Labor relations. 1422.101 Section 1422.101 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 1422.101 Labor relations....

  5. 48 CFR 1322.101 - Labor relations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Labor relations. 1322.101 Section 1322.101 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 1322.101 Labor relations....

  6. 48 CFR 1422.101 - Labor relations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Labor relations. 1422.101 Section 1422.101 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 1422.101 Labor relations....

  7. 48 CFR 1222.101 - Labor relations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Labor relations. 1222.101 Section 1222.101 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 1222.101 Labor relations....

  8. 48 CFR 1422.101 - Labor relations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Labor relations. 1422.101 Section 1422.101 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 1422.101 Labor relations....

  9. 48 CFR 22.101 - Labor relations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Labor relations. 22.101 Section 22.101 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 22.101 Labor relations....

  10. 48 CFR 1222.101 - Labor relations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Labor relations. 1222.101 Section 1222.101 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 1222.101 Labor relations....

  11. 48 CFR 522.101 - Labor relations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Labor relations. 522.101 Section 522.101 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 522.101 Labor relations....

  12. 48 CFR 522.101 - Labor relations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Labor relations. 522.101 Section 522.101 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 522.101 Labor relations....

  13. Department of Labor Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... of Employee Rights Under Federal Labor Laws 1245-AA00 398 Form T-1: Reports by Labor Organizations on... describe the rights of employees under Federal labor laws, consistent with the policy set forth in section..., Pension Law Specialist, Department of Labor, Employee Benefits Security Administration, 200...

  14. 48 CFR 522.101 - Labor relations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Labor relations. 522.101 Section 522.101 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Basic Labor Policies 522.101 Labor relations....

  15. 24 CFR 585.313 - Labor standards.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) Laborers and mechanics other than Youthbuild Trainees. (1) All laborers and mechanics (other than... such laborers and mechanics on assisted housing shall be subject to the provisions of the Contract Work... standards apply to laborers and mechanics other than Youthbuild trainees to the extent required by the...

  16. Labor Market Participation, Returns to Education, and Male-Female Wage Differences in Peru.

    ERIC Educational Resources Information Center

    Khandker, Shahidur R.

    Based on a human capital model, this paper uses household survey data from Peru to estimate differences between males and females in labor-market participation, productivity (measured in wages), and economic returns to education. The focus is on human capital, especially education, as a determinant of labor participation and productivity. The…

  17. Clandestine labor migration to Taiwan.

    PubMed

    Tsay, C

    1992-01-01

    "Illegal migration to Taiwan is a recent phenomenon but with a rapid rate of increase. Most illegal foreign workers enter on visitor's visas and overstay. This paper's detailed analysis of official data reveals that Malaysia, Philippines, Indonesia and Thailand are the major sources, providing a stock of mostly male workers numbering around 40,000. Sociodemographic and attitudinal changes among Taiwanese workers coupled with labor shortages in low-skilled jobs are pressuring the Taiwanese government to formulate plans for a systematic importation of foreign labor." PMID:12285774

  18. Hypnotherapy for labor and birth.

    PubMed

    Beebe, Kathleen R

    2014-01-01

    Hypnotherapy is an integrative mind-body technique with therapeutic potential in various health care applications, including labor and birth. Evaluating the efficacy of this modality in controlled studies can be difficult, because of methodologic challenges, such as obtaining adequate sample sizes and standardizing experimental conditions. Women using hypnosis techniques for childbirth in hospital settings may face barriers related to caregiver resistance or institutional policies. The potential anxiolytic and analgesic effects of clinical hypnosis for childbirth merit further study. Nurses caring for women during labor and birth can increase their knowledge and skills with strategies for supporting hypnotherapeutic techniques. PMID:24548496

  19. Hypnotherapy for labor and birth.

    PubMed

    Beebe, Kathleen R

    2014-01-01

    Hypnotherapy is an integrative mind-body technique with therapeutic potential in various health care applications, including labor and birth. Evaluating the efficacy of this modality in controlled studies can be difficult, because of methodologic challenges, such as obtaining adequate sample sizes and standardizing experimental conditions. Women using hypnosis techniques for childbirth in hospital settings may face barriers related to caregiver resistance or institutional policies. The potential anxiolytic and analgesic effects of clinical hypnosis for childbirth merit further study. Nurses caring for women during labor and birth can increase their knowledge and skills with strategies for supporting hypnotherapeutic techniques.

  20. Clandestine labor migration to Taiwan.

    PubMed

    Tsay, C

    1992-01-01

    "Illegal migration to Taiwan is a recent phenomenon but with a rapid rate of increase. Most illegal foreign workers enter on visitor's visas and overstay. This paper's detailed analysis of official data reveals that Malaysia, Philippines, Indonesia and Thailand are the major sources, providing a stock of mostly male workers numbering around 40,000. Sociodemographic and attitudinal changes among Taiwanese workers coupled with labor shortages in low-skilled jobs are pressuring the Taiwanese government to formulate plans for a systematic importation of foreign labor."

  1. The Effect of Florida's Bright Futures Program on College Enrollment and Degree Production: An Aggregated-Level Analysis

    ERIC Educational Resources Information Center

    Zhang, Liang; Hu, Shouping; Sensenig, Victor

    2013-01-01

    In this study, we investigate the impact of the Bright Futures Scholarship Program on college enrollment and degree production in Florida by using IPEDS enrollment, migration, and completion data. Results suggest large and significant enrollment effects at Florida's public 4- and 2-year institutions, for both full-time and part-time…

  2. Planktonic Aggregates of Staphylococcus aureus Protect against Common Antibiotics

    PubMed Central

    Haaber, Jakob; Cohn, Marianne Thorup; Frees, Dorte; Andersen, Thorbjørn Joest; Ingmer, Hanne

    2012-01-01

    Bacterial cells are mostly studied during planktonic growth although in their natural habitats they are often found in communities such as biofilms with dramatically different physiological properties. We have examined another type of community namely cellular aggregates observed in strains of the human pathogen Staphylococcus aureus. By laser-diffraction particle–size analysis (LDA) we show, for strains forming visible aggregates, that the aggregation starts already in the early exponential growth phase and proceeds until post-exponential phase where more than 90% of the population is part of the aggregate community. Similar to some types of biofilm, the structural component of S. aureus aggregates is the polysaccharide intercellular adhesin (PIA). Importantly, PIA production correlates with the level of aggregation whether altered through mutations or exposure to sub-inhibitory concentrations of selected antibiotics. While some properties of aggregates resemble those of biofilms including increased mutation frequency and survival during antibiotic treatment, aggregated cells displayed higher metabolic activity than planktonic cells or cells in biofilm. Thus, our data indicate that the properties of cells in aggregates differ in some aspects from those in biofilms. It is generally accepted that the biofilm life style protects pathogens against antibiotics and the hostile environment of the host. We speculate that in aggregate communities S. aureus increases its tolerance to hazardous environments and that the combination of a biofilm-like environment with mobility has substantial practical and clinical importance. PMID:22815921

  3. Properties of Concrete with Tire Derived Aggregate Partially Replacing Coarse Aggregates

    PubMed Central

    Siringi, Gideon; Abolmaali, Ali; Aswath, Pranesh B.

    2015-01-01

    Tire derived aggregate (TDA) has been proposed as a possible lightweight replacement for mineral aggregate in concrete. The role played by the amount of TDA replacing coarse aggregate as well as different treatment and additives in concrete on its properties is examined. Conventional concrete (without TDA) and concrete containing TDA are compared by examining their compressive strength based on ASTM C39, workability based on ASTM C143, splitting tensile strength based on ASTM C496, modulus of rupture (flexural strength) based on ASTM C78, and bond stress based on ASTM C234. Results indicate that while replacement of coarse aggregates with TDA results in reduction in strength, it may be mitigated with addition of silica fume to obtain the desired strength. The greatest benefit of using TDA is in the development of a higher ductile product while utilizing recycled TDA. PMID:26161440

  4. Properties of Concrete with Tire Derived Aggregate Partially Replacing Coarse Aggregates.

    PubMed

    Siringi, Gideon; Abolmaali, Ali; Aswath, Pranesh B

    2015-01-01

    Tire derived aggregate (TDA) has been proposed as a possible lightweight replacement for mineral aggregate in concrete. The role played by the amount of TDA replacing coarse aggregate as well as different treatment and additives in concrete on its properties is examined. Conventional concrete (without TDA) and concrete containing TDA are compared by examining their compressive strength based on ASTM C39, workability based on ASTM C143, splitting tensile strength based on ASTM C496, modulus of rupture (flexural strength) based on ASTM C78, and bond stress based on ASTM C234. Results indicate that while replacement of coarse aggregates with TDA results in reduction in strength, it may be mitigated with addition of silica fume to obtain the desired strength. The greatest benefit of using TDA is in the development of a higher ductile product while utilizing recycled TDA. PMID:26161440

  5. Properties of Concrete with Tire Derived Aggregate Partially Replacing Coarse Aggregates.

    PubMed

    Siringi, Gideon; Abolmaali, Ali; Aswath, Pranesh B

    2015-01-01

    Tire derived aggregate (TDA) has been proposed as a possible lightweight replacement for mineral aggregate in concrete. The role played by the amount of TDA replacing coarse aggregate as well as different treatment and additives in concrete on its properties is examined. Conventional concrete (without TDA) and concrete containing TDA are compared by examining their compressive strength based on ASTM C39, workability based on ASTM C143, splitting tensile strength based on ASTM C496, modulus of rupture (flexural strength) based on ASTM C78, and bond stress based on ASTM C234. Results indicate that while replacement of coarse aggregates with TDA results in reduction in strength, it may be mitigated with addition of silica fume to obtain the desired strength. The greatest benefit of using TDA is in the development of a higher ductile product while utilizing recycled TDA.

  6. Determination of the dynamic elastic constants of recycled aggregate concrete

    NASA Astrophysics Data System (ADS)

    Tsoumani, A. A.; Barkoula, N.-M.; Matikas, T. E.

    2015-03-01

    Nowadays, construction and demolition waste constitutes a major portion of the total solid waste production in the world. Due to both environmental and economical reasons, an increasing interest concerning the use of recycled aggregate to replace aggregate from natural sources is generated. This paper presents an investigation on the properties of recycled aggregate concrete. Concrete mixes are prepared using recycled aggregates at a substitution level between 0 and 100% of the total coarse aggregate. The influence of this replacement on strengthened concrete's properties is being investigated. The properties estimated are: density and dynamic modulus of elasticity at the age of both 7 and 28 days. Also, flexural strength of 28 days specimens is estimated. The determination of the dynamic elastic modulus was made using the ultrasonic pulse velocity method. The results reveal that the existence of recycled aggregates affects the properties of concrete negatively; however, in low levels of substitution the influence of using recycled aggregates is almost negligible. Concluding, the controlled use of recycled aggregates in concrete production may help solve a vital environmental issue apart from being a solution to the problem of inadequate concrete aggregates.

  7. Proteins aggregation and human diseases

    NASA Astrophysics Data System (ADS)

    Hu, Chin-Kun

    2015-04-01

    Many human diseases and the death of most supercentenarians are related to protein aggregation. Neurodegenerative diseases include Alzheimer's disease (AD), Huntington's disease (HD), Parkinson's disease (PD), frontotemporallobar degeneration, etc. Such diseases are due to progressive loss of structure or function of neurons caused by protein aggregation. For example, AD is considered to be related to aggregation of Aβ40 (peptide with 40 amino acids) and Aβ42 (peptide with 42 amino acids) and HD is considered to be related to aggregation of polyQ (polyglutamine) peptides. In this paper, we briefly review our recent discovery of key factors for protein aggregation. We used a lattice model to study the aggregation rates of proteins and found that the probability for a protein sequence to appear in the conformation of the aggregated state can be used to determine the temperature at which proteins can aggregate most quickly. We used molecular dynamics and simple models of polymer chains to study relaxation and aggregation of proteins under various conditions and found that when the bending-angle dependent and torsion-angle dependent interactions are zero or very small, then protein chains tend to aggregate at lower temperatures. All atom models were used to identify a key peptide chain for the aggregation of insulin chains and to find that two polyQ chains prefer anti-parallel conformation. It is pointed out that in many cases, protein aggregation does not result from protein mis-folding. A potential drug from Chinese medicine was found for Alzheimer's disease.

  8. Aggregation of organic matter by pelagic tunicates

    SciTech Connect

    Pomeroy, L.R.; Deibel, D.

    1980-07-01

    Three genera of pelagic tunicates were fed concentrates of natural seston and an axenic diatom culture. Fresh and up to 4-day-old feces resemble flocculent organic aggregates containing populations of microorganisms, as described from highly productive parts of the ocean, and older feces resemble the nearly sterile flocculent aggregates which are ubiquitous in surface waters. Fresh feces consist of partially digested phytoplankton and other inclusions in an amorphous gelatinous matrix. After 18 to 36 h, a population of large bacteria develops in the matrix and in some of the remains of phytoplankton contained in the feces. From 48 to 96 h, protozoan populations arise which consume the bacteria and sometimes the remains of the phytoplankton in the feces. Thereafter only a sparse population of microorganisms remains, and the particles begin to fragment. Water samples taken in or below dense populations of salps and doliolids contained greater numbers of flocculent aggregates than did samples from adjacent stations.

  9. Labor Relations. Trends and Issues.

    ERIC Educational Resources Information Center

    Brown, Kara, Comp.

    This paper examines labor issues that affect school employees. It is divided into four sections: school reform; teacher compensation; scope of bargaining; and collaborative (nonadversarial) bargaining. The longest section, which focuses on various reform movements in the schools, examines accountability, school choice, and the questions…

  10. Academic Labor Markets and Careers.

    ERIC Educational Resources Information Center

    Breneman, David W., Ed.; Youn, Ted I. K., Ed.

    As part of the Stanford Series on Education and Public Policy, academic careers and academic labor markets in American higher education are examined from a perspective based on both economic reasoning and sociological analysis. Research common to both fields is considered in a series of 10 essays that discuss the following subjects: "Studies of…

  11. Library Labor Cost Accounting System.

    ERIC Educational Resources Information Center

    Du Bois, Dan

    The Library Labor Cost Accounting System will provide visibility on current costs of manually processing library materials, at each campus as well as system-wide. The scope of the study includes the following: (1) 100 individual activities, grouped into 14 functional areas, e.g., Ordering, Receiving; and into 3 major operations: Acquisitions,…

  12. Pennsylvania Migratory Labor Program Report.

    ERIC Educational Resources Information Center

    Governor's Committee on Migratory Labor, Harrisburg, PA.

    Operating for the 18th year, the Pennsylvania Governor's Committee on Migratory Labor, which is charged with coordinating and bringing into focus the activities of various governmental and nongovernmental agencies relating to Pennsylvania's migrant workers, submits the present document as an annual report. Some specific areas reported on by…

  13. Labor Policy, Minorities, and Youth.

    ERIC Educational Resources Information Center

    Lincoln Inst. for Research and Education, Washington, DC.

    The central theme of the papers presented in this symposium is that the labor market for minorities and youth does not appear to function properly because of structural impediments (often caused by government regulations meant to help minorities) and that these impediments must be identified and effective remedies proposed. Following an…

  14. Child Labor Laws in Mississippi.

    ERIC Educational Resources Information Center

    Robbins, Jerry H.

    Child labor laws have not attracted much attention in recent years. Much of the basic legislation and the case law dates from the early part of the 20th century. This paper discusses the Mississippi statutory law on the subject, compares that law with legislation in five other States, and discusses case law in Mississippi and in other States.…

  15. BUREAU OF MIGRANT LABOR REPORT.

    ERIC Educational Resources Information Center

    YERSAK, CHARLES G.

    A GRADUAL REDUCTION IN MIGRANT LABOR HAS OCCURRED IN NEW JERSEY BECAUSE OF MECHANIZATION AND URBANIZATION. THIS REDUCTION IS REFLECTED IN FEWER ACTIVE CAMPS THAT HOUSE WORKERS. THE TREND IS AWAY FROM THE USE OF FRAME BUILDINGS AND NEW CAMPS BEING BUILT ARE CONSTRUCTED OF CINDER BLOCK. THE MIGRANT FORCE IS LARGELY COMPOSED OF NEGROES FROM THE SOUTH…

  16. A Compilation of Job Training and Related Laws. Prepared by the Subcommittee on Employment and Productivity of the Committee on Labor and Human Resources. 99th Congress, 2nd Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Committee on Labor and Human Resources.

    This compilation is intended to assist the general public in gaining a further understanding of the work of the Committee on Labor and Human Resources to provide legislative assistance to Americans who are economically disadvantaged or structurally unemployed. The texts of the following pieces of federal legislation are included: the Job Training…

  17. Comparative environmental assessment of natural and recycled aggregate concrete.

    PubMed

    Marinković, S; Radonjanin, V; Malešev, M; Ignjatović, I

    2010-11-01

    Constant and rapid increase in construction and demolition (C&D) waste generation and consumption of natural aggregate for concrete production became one of the biggest environmental problems in the construction industry. Recycling of C&D waste represents one way to convert a waste product into a resource but the environment benefits through energy consumption, emissions and fallouts reductions are not certain. The main purpose of this study is to determine the potentials of recycled aggregate concrete (concrete made with recycled concrete aggregate) for structural applications and to compare the environmental impact of the production of two types of ready-mixed concrete: natural aggregate concrete (NAC) made entirely with river aggregate and recycled aggregate concrete (RAC) made with natural fine and recycled coarse aggregate. Based on the analysis of up-to-date experimental evidence, including own tests results, it is concluded that utilization of RAC for low-to-middle strength structural concrete and non-aggressive exposure conditions is technically feasible. The Life Cycle Assessment (LCA) is performed for raw material extraction and material production part of the concrete life cycle including transport. Assessment is based on local LCI data and on typical conditions in Serbia. Results of this specific case study show that impacts of aggregate and cement production phases are slightly larger for RAC than for NAC but the total environmental impacts depend on the natural and recycled aggregates transport distances and on transport types. Limit natural aggregate transport distances above which the environmental impacts of RAC can be equal or even lower than the impacts of NAC are calculated for the specific case study. PMID:20434898

  18. Comparative environmental assessment of natural and recycled aggregate concrete.

    PubMed

    Marinković, S; Radonjanin, V; Malešev, M; Ignjatović, I

    2010-11-01

    Constant and rapid increase in construction and demolition (C&D) waste generation and consumption of natural aggregate for concrete production became one of the biggest environmental problems in the construction industry. Recycling of C&D waste represents one way to convert a waste product into a resource but the environment benefits through energy consumption, emissions and fallouts reductions are not certain. The main purpose of this study is to determine the potentials of recycled aggregate concrete (concrete made with recycled concrete aggregate) for structural applications and to compare the environmental impact of the production of two types of ready-mixed concrete: natural aggregate concrete (NAC) made entirely with river aggregate and recycled aggregate concrete (RAC) made with natural fine and recycled coarse aggregate. Based on the analysis of up-to-date experimental evidence, including own tests results, it is concluded that utilization of RAC for low-to-middle strength structural concrete and non-aggressive exposure conditions is technically feasible. The Life Cycle Assessment (LCA) is performed for raw material extraction and material production part of the concrete life cycle including transport. Assessment is based on local LCI data and on typical conditions in Serbia. Results of this specific case study show that impacts of aggregate and cement production phases are slightly larger for RAC than for NAC but the total environmental impacts depend on the natural and recycled aggregates transport distances and on transport types. Limit natural aggregate transport distances above which the environmental impacts of RAC can be equal or even lower than the impacts of NAC are calculated for the specific case study.

  19. Dynamics of fire ant aggregations

    NASA Astrophysics Data System (ADS)

    Tennenbaum, Michael; Hu, David; Fernandez-Nieves, Alberto

    Fire ant aggregations are an inherently active system. Each ant harvests its own energy and can convert it into motion. The motion of individual ants contributes non-trivially to the bulk material properties of the aggregation. We have measured some of these properties using plate-plate rheology, where the response to an applied external force or deformation is measured. In this talk, we will present data pertaining to the aggregation behavior in the absence of any external force. We quantify the aggregation dynamics by monitoring the rotation of the top plate and by measuring the normal force. We then compare the results with visualizations of 2D aggregations.

  20. Collisional Aggregation Due to Turbulence

    NASA Astrophysics Data System (ADS)

    Pumir, Alain; Wilkinson, Michael

    2016-03-01

    Collisions between particles suspended in a fluid play an important role in many physical processes. As an example, collisions of microscopic water droplets in clouds are a necessary step in the production of macroscopic raindrops. Collisions of dust grains are also conjectured to be important for planet formation in the gas surrounding young stars and to play a role in the dynamics of sand storms. In these processes, collisions are favored by fast turbulent motions. Here we review recent advances in the understanding of collisional aggregation due to turbulence. We discuss the role of fractal clustering of particles and caustic singularities of their velocities. We also discuss limitations of the Smoluchowski equation for modeling such processes. These advances lead to a semiquantitative understanding on the influence of turbulence on collision rates and point to deficiencies in the current understanding of rainfall and planet formation.

  1. Gut bacteria mediate aggregation in the German cockroach

    PubMed Central

    Wada-Katsumata, Ayako; Zurek, Ludek; Nalyanya, Godfrey; Roelofs, Wendell L.; Zhang, Aijun; Schal, Coby

    2015-01-01

    Aggregation of the German cockroach, Blattella germanica, is regulated by fecal aggregation agents (pheromones), including volatile carboxylic acids (VCAs). We demonstrate that the gut microbial community contributes to production of these semiochemicals. Chemical analysis of the fecal extract of B. germanica revealed 40 VCAs. Feces from axenic cockroaches (no microorganisms in the alimentary tract) lacked 12 major fecal VCAs, and 24 of the remaining compounds were represented at extremely low amounts. Olfactory and aggregation bioassays demonstrated that nymphs strongly preferred the extract of control feces over the fecal extract of axenic cockroaches. Additionally, nymphs preferred a synthetic blend of 6 fecal VCAs over a solvent control or a previously identified VCA blend. To test whether gut bacteria contribute to the production of fecal aggregation agents, fecal aerobic bacteria were cultured, isolated, and identified. Inoculation of axenic cockroaches with individual bacterial taxa significantly rescued the aggregation response to the fecal extract, and inoculation with a mix of six bacterial isolates was more effective than with single isolates. The results indicate that the commensal gut microbiota contributes to production of VCAs that act as fecal aggregation agents and that cockroaches discriminate among the complex odors that emanate from a diverse microbial community. Our results highlight the pivotal role of gut bacteria in mediating insect–insect communication. Moreover, because the gut microbial community reflects the local environment, local plasticity in fecal aggregation pheromones enables colony-specific odors and fidelity to persistent aggregation sites. PMID:26644557

  2. Kinetics of protein aggregation

    NASA Astrophysics Data System (ADS)

    Knowles, Tuomas

    2015-03-01

    Aggregation into linear nanostructures, notably amyloid and amyloid-like fibrils, is a common form of behaviour exhibited by a range of peptides and proteins. This process was initially discovered in the context of the aetiology of a range of neurodegenerative diseases, but has recently been recognised to of general significance and has been found at the origin of a number of beneficial functional roles in nature, including as catalytic scaffolds and functional components in biofilms. This talk discusses our ongoing efforts to study the kinetics of linear protein self-assembly by using master equation approaches combined with global analysis of experimental data.

  3. Structure of Viral Aggregates

    NASA Astrophysics Data System (ADS)

    Barr, Stephen; Luijten, Erik

    2010-03-01

    The aggregation of virus particles is a particular form of colloidal self-assembly, since viruses of a give type are monodisperse and have identical, anisotropic surface charge distributions. In small-angle X-ray scattering experiments, the Qbeta virus was found to organize in different crystal structures in the presence of divalent salt and non-adsorbing polymer. Since a simple isotropic potential cannot explain the occurrence of all observed phases, we employ computer simulations to investigate how the surface charge distribution affects the virus interactions. Using a detailed model of the virus particle, we find an asymmetric ion distribution around the virus which gives rise to the different phases observed.

  4. From Aggregate Availability to Sustainability in California

    NASA Astrophysics Data System (ADS)

    Testa, S. M.; Parrish, J. G.

    2012-12-01

    California leads the nation in the production of sand and gravel, and ranks second behind Texas in the production of portland cement. Prior to 1960, the California Geological Survey (CGS, formerly the Division of Mines and Geology) and the State Mining and Geology Board (SMGB, formerly State Mining Board) placed an emphasis "in obtaining and providing information of benefit to the State's mineral industry". By the late 1960s, the Division initiated activities in the area of geologic hazards, and also expressed concern over the loss of aggregate resources via urbanization, which were among the state's most valuable mineral resource. Under the California Surface Mining and Reclamation Act of 1975 (SMARA), the State Geologist classifies mineral resources solely on geologic factors, and without regard to existing land use and land ownership. Following classification, the SMGB may consider "designating" such lands should the classified area contain mineral resources of regional or statewide economic significance and that may be needed to meet future demands. In 1979, the classification of aggregate resources in the three-county area of Los Angeles, Orange, and Ventura, was completed, with designation of such resources in Los Angeles County in 1981. Maps and descriptions of the designated mineral lands were placed in the California Public Resources Code and officially transmitted to those county and city governments having permitting authority over the use of those lands. In 1999, the SMGB in concert with CGS implemented the SMARA Regional Synthesis Map series, with the first (and last) of the series covering the Los Angeles Basin. This map was very useful for regional planners and the general citizenry since it provided a broader perspective not readily apparent in the smaller scale Production-Consumption (P-C) regional maps. CGS's statewide Aggregate Availability Map, commonly referred to as Map Sheet 52, was developed in 2002 and updated in 2006. The purpose of Map 52

  5. State Labor Legislation Enacted in 1993.

    ERIC Educational Resources Information Center

    Nelson, Richard R.

    1994-01-01

    Looks at labor legislation enacted by states in 1993 in terms of wages, family issues, child labor, equal employment opportunity, employee drug and alcohol testing, employee leasing, resident preference, and whistleblowers. (JOW)

  6. Working Children: A Report on Child Labor.

    ERIC Educational Resources Information Center

    Department of Labor, Washington, DC.

    This report explains the applicability of the Fair Labor Standards Act to child labor. Statistics are provided on violations which occurred during fiscal year 1970, and individual cases are described. This document is a revision of ED 048 498. (BH)

  7. International Labor Organization's 75th Anniversary.

    ERIC Educational Resources Information Center

    Hansenne, Michel; And Others

    1994-01-01

    This special issue contains eight articles that examine the following: social justice, global employment issues, International Labor Organization (ILO) standards, social security, training, tripartism, the 1994 ILO conference, and labor standards--all from a global perspective. (JOW)

  8. Labor Requirements for College-Housing Construction.

    ERIC Educational Resources Information Center

    Bingham, Barbara J.

    1979-01-01

    Labor requirements dropped about 20 percent during a nine-year period, partially because of labor-saving devices such as modular and prefabricated units. During the same period, the cost of building college housing increased 74 percent. (Editor)

  9. "A Welcome Debate" over Labor Reform

    ERIC Educational Resources Information Center

    Warren, Cat

    2010-01-01

    This article presents an interview with Wilma B. Liebman, the new chair of the National Labor Relations Board (NLRB). In this interview, Liebman talks about labor law, academics, and reversing ossification.

  10. 29 CFR 780.115 - Forest products.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Forest products. 780.115 Section 780.115 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR... Agricultural Or Horticultural Commodities § 780.115 Forest products. Trees grown in forests and the...

  11. 29 CFR 780.115 - Forest products.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Forest products. 780.115 Section 780.115 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR... Agricultural Or Horticultural Commodities § 780.115 Forest products. Trees grown in forests and the...

  12. 29 CFR 780.115 - Forest products.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Forest products. 780.115 Section 780.115 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR... Agricultural Or Horticultural Commodities § 780.115 Forest products. Trees grown in forests and the...

  13. 29 CFR 780.115 - Forest products.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Forest products. 780.115 Section 780.115 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR... Agricultural Or Horticultural Commodities § 780.115 Forest products. Trees grown in forests and the...

  14. 29 CFR 780.115 - Forest products.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Forest products. 780.115 Section 780.115 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR... Agricultural Or Horticultural Commodities § 780.115 Forest products. Trees grown in forests and the...

  15. The Impact of New College Graduates on Intrastate Labor Markets

    ERIC Educational Resources Information Center

    Trostel, Philip A.

    2010-01-01

    A crucial issue in the debate on state support for higher education is the extent that a state's production of college graduates affects the state's education attainment. The view that many new graduates take their state-supported degrees to labor markets in other states undermines states' incentives to promote wider access to college. This study…

  16. 26 CFR 31.3121(g)-1 - Agricultural labor.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... labor. For example the extraction of juices from fruits or vegetables is a processing operation which... “commodity” refers to a single agricultural or horticultural product, for example, all apples are to be treated as a single commodity, while apples and peaches are to be treated as two separate commodities....

  17. 26 CFR 31.3121(g)-1 - Agricultural labor.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... labor. For example the extraction of juices from fruits or vegetables is a processing operation which... “commodity” refers to a single agricultural or horticultural product, for example, all apples are to be treated as a single commodity, while apples and peaches are to be treated as two separate commodities....

  18. 26 CFR 31.3121(g)-1 - Agricultural labor.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... labor. For example the extraction of juices from fruits or vegetables is a processing operation which... “commodity” refers to a single agricultural or horticultural product, for example, all apples are to be treated as a single commodity, while apples and peaches are to be treated as two separate commodities....

  19. 26 CFR 31.3121(g)-1 - Agricultural labor.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... labor. For example the extraction of juices from fruits or vegetables is a processing operation which... “commodity” refers to a single agricultural or horticultural product, for example, all apples are to be treated as a single commodity, while apples and peaches are to be treated as two separate commodities....

  20. 26 CFR 31.3121(g)-1 - Agricultural labor.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... labor. For example the extraction of juices from fruits or vegetables is a processing operation which... “commodity” refers to a single agricultural or horticultural product, for example, all apples are to be treated as a single commodity, while apples and peaches are to be treated as two separate commodities....

  1. DataTrack 7: Women in the Labor Force.

    ERIC Educational Resources Information Center

    American Council of Life Insurance, Washington, DC.

    One of a series that compiles and interprets data from a variety of sources on one particular subject of interest to life insurance executives, this report deals with women in the labor force. It can be used in the design of new products and services, to meet changing consumer needs, the selection of new markets and marketing strategies, for the…

  2. The Plant Closure Policy Dilemma. Labor, Law and Bargaining.

    ERIC Educational Resources Information Center

    Wendling, Wayne R.

    In 1982 plant closings in the United States affected approximately 1 percent of the country's manufacturing facilities and 1 percent of its manufacturing labor force. Included among the reasons cited for plant closings were low productivity, high wages, and inflexible work rules. Given the nature of the reasons for plant closings and the magnitude…

  3. China's export of labor and its management.

    PubMed

    Wang, S

    1995-01-01

    "This research note presents trends and data on China's labor export from 1979-1991. By 1990, China had deployed over 400,000 workers in 139 countries and regions, with labor export becoming an important source of foreign exchange. Data include China's contract value and number of workers annually; international distribution of Chinese workers; comparative figures for construction; contractors and labor cooperatives; and China's labor exports by corporation."

  4. Labor induction: a review of current methods.

    PubMed

    Ramirez, Mildred M

    2011-06-01

    This article reviews the essential criteria for inductions of labor, weighing both the advantages and disadvantages of labor induction, and the various mechanical and pharmacologic agents available for cervical ripening. At the end of this article, one should be able to counsel women about the potential risks and benefit of labor induction and understand the neonatal consequences of elective induction of labor before 39 weeks of gestation. This article also discusses the different mechanical and pharmacologic agents available for cervical ripening.

  5. Taurine and platelet aggregation

    SciTech Connect

    Nauss-Karol, C.; VanderWende, C.; Gaut, Z.N.

    1986-03-01

    Taurine is a putative neurotransmitter or neuromodulator. The endogenous taurine concentration in human platelets, determined by amino acid analysis, is 15 ..mu..M/g. In spite of this high level, taurine is actively accumulated. Uptake is saturable, Na/sup +/ and temperature dependent, and suppressed by metabolic inhibitors, structural analogues, and several classes of centrally active substances. High, medium and low affinity transport processes have been characterized, and the platelet may represent a model system for taurine transport in the CNS. When platelets were incubated with /sup 14/C-taurine for 30 minutes, then resuspended in fresh medium and reincubated for one hour, essentially all of the taurine was retained within the cells. Taurine, at concentrations ranging from 10-1000 ..mu..M, had no effect on platelet aggregation induced by ADP or epinephrine. However, taurine may have a role in platelet aggregation since 35-39% of the taurine taken up by human platelets appears to be secreted during the release reaction induced by low concentrations of either epinephrine or ADP, respectively. This release phenomenon would imply that part of the taurine taken up is stored directly in the dense bodies of the platelet.

  6. Solar Installation Labor Market Analysis

    SciTech Connect

    Friedman, B.; Jordan, P.; Carrese, J.

    2011-12-01

    The potential economic benefits of the growing renewable energy sector have led to increased federal, state, and local investments in solar industries, including federal grants for expanded workforce training for U.S. solar installers. However, there remain gaps in the data required to understand the size and composition of the workforce needed to meet the demand for solar power. Through primary research on the U.S. solar installation employer base, this report seeks to address that gap, improving policymakers and other solar stakeholders understanding of both the evolving needs of these employers and the economic opportunity associated with solar market development. Included are labor market data covering current U.S. employment, expected industry growth, and employer skill preferences for solar installation-related occupations. This study offers an in-depth look at the solar installation sectors. A study published by the Solar Foundation in October 2011 provides a census of labor data across the entire solar value chain.

  7. The Bright Side of Corporate Diversification: Evidence from Internal Labor Markets

    PubMed Central

    Tate, Geoffrey

    2015-01-01

    We document differences in human-capital deployment between diversified and focused firms. We find that diversified firms have higher labor productivity and that they redeploy labor to industries with better prospects in response to changing opportunities. The opportunities and incentives provided in internal labor markets in turn affect the development of workers' human capital. We find that workers more frequently transition to other industries in which their diversified firms operate and with smaller wage losses compared with workers in the open market, even when they leave their original firms. Overall, internal labor markets provide a bright side to corporate diversification. PMID:26924889

  8. Timing of induction of labor.

    PubMed

    Bacak, Stephen J; Olson-Chen, Courtney; Pressman, Eva

    2015-10-01

    Determining the optimal timing for induction of labor is critical in minimizing the risks to maternal and fetal health. While data are available to guide us in some clinical situations, such as hypertension and diabetes, many gaps in knowledge still exist in others, including cholestasis of pregnancy, fetal anomalies, and placental abruption. This review of the currently available literature assesses the risks and benefits of preterm and early term induction in a wide variety of maternal and fetal conditions.

  9. Native Americans and Wage Labor: Ethnohistorical Perspectives.

    ERIC Educational Resources Information Center

    Littlefield, Alice, Ed.; Knack, Martha C., Ed.

    This book reconsiders a largely ignored fact of North American Indian economic life--the place of wage labor in the culture and history of Native Americans. Case studies examine social networks of Native agricultural laborers, the decline of Native communities from self-sufficient producers to lower-class wage laborers, vocational education in…

  10. 10 CFR 440.19 - Labor.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Labor. 440.19 Section 440.19 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION WEATHERIZATION ASSISTANCE FOR LOW-INCOME PERSONS § 440.19 Labor. Payments for labor... supplement wages paid to training participants, public service employment workers, or other Federal or...

  11. State Labor Legislation Enacted in 1998.

    ERIC Educational Resources Information Center

    Nelson, Richard R.

    1999-01-01

    Identifies major subjects of state labor legislation in 1998: increases in minimum-wage rates, prevailing wage changes, child-labor revisions, workplace surveillance regulations, and bans on employment discrimination. Offers a state-by-state summary of labor legislation. (JOW)

  12. Emotional Labor: A Conceptualization and Scale Development

    ERIC Educational Resources Information Center

    Glomb, Theresa M.; Tews, Michael J.

    2004-01-01

    Despite increased research attention, the emotional labor construct remains without a clear conceptualization and operationalization. This study designed a conceptually grounded, psychometrically sound instrument to measure emotional labor with an emphasis on the experience of discrete emotions-the Discrete Emotions Emotional Labor Scale (DEELS).…

  13. State Labor Legislation Enacted in 1988.

    ERIC Educational Resources Information Center

    Nelson, Richard R.

    1989-01-01

    Reviews labor legislation enacted by each state during 1988. Covers such labor issues as (1) wages, (2) parental leave, (3) child labor, (4) discrimination, (5) employee testing for drug or alcohol abuse or for Acquired Immune Deficiency Syndrome, (6) private employment agencies, and (7) safety and health. (CH)

  14. 23 CFR 140.906 - Labor costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Labor costs. 140.906 Section 140.906 Highways FEDERAL... Railroad Work § 140.906 Labor costs. (a) General. (1) Salaries and wages, at actual or average rates, and... reimbursable when supported by adequate records. This shall include labor costs associated with...

  15. 23 CFR 140.906 - Labor costs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... engineering, construction engineering, right-of-way, and force account construction. (2) Salaries and expenses... may be reimbursed. (b) Labor surcharges. (1) Labor surcharges include worker compensation insurance... the company, a fixed rate of 8 percent of direct labor costs for worker compensation and...

  16. Child Labor and School Attendance in Kenya

    ERIC Educational Resources Information Center

    Moyi, Peter

    2011-01-01

    Sub-Saharan Africa has the highest incidence of child labor in the world and estimates show that it continues to grow. This paper examines the causes and magnitude of child labor in Kenya. Unlike previous studies that examined child labor as only an economic activity, this paper includes household chores. Including household chores is important…

  17. 22 CFR 901.19 - Labor organization.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Labor organization. 901.19 Section 901.19 Foreign Relations FOREIGN SERVICE GRIEVANCE BOARD GENERAL Meanings of Terms As Used in This Chapter § 901.19 Labor organization. Labor organization means any employee organization accorded recognition as...

  18. 22 CFR 901.19 - Labor organization.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Labor organization. 901.19 Section 901.19 Foreign Relations FOREIGN SERVICE GRIEVANCE BOARD GENERAL Meanings of Terms As Used in This Chapter § 901.19 Labor organization. Labor organization means any employee organization accorded recognition as...

  19. 22 CFR 901.19 - Labor organization.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Labor organization. 901.19 Section 901.19 Foreign Relations FOREIGN SERVICE GRIEVANCE BOARD GENERAL Meanings of Terms As Used in This Chapter § 901.19 Labor organization. Labor organization means any employee organization accorded recognition as...

  20. 22 CFR 901.19 - Labor organization.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Labor organization. 901.19 Section 901.19 Foreign Relations FOREIGN SERVICE GRIEVANCE BOARD GENERAL Meanings of Terms As Used in This Chapter § 901.19 Labor organization. Labor organization means any employee organization accorded recognition as...

  1. 22 CFR 901.19 - Labor organization.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Labor organization. 901.19 Section 901.19 Foreign Relations FOREIGN SERVICE GRIEVANCE BOARD GENERAL Meanings of Terms As Used in This Chapter § 901.19 Labor organization. Labor organization means any employee organization accorded recognition as...

  2. State Labor Legislation Enacted in 1985.

    ERIC Educational Resources Information Center

    Nelson, Richard R.

    1986-01-01

    Presents a summary, by state jurisdiction, of labor legislation during 1985. Legislation covered such topics as wages, equal employment opportunity, background clearance, occupational safety and health, employment and training, child labor, industrial homework, hours, agriculture, labor relations, plant closings, worker privacy, private employment…

  3. State Labor Legislation Enacted in 1984.

    ERIC Educational Resources Information Center

    Nelson, Richard R.

    1985-01-01

    Summaries are presented, by state, of labor standards legislation passed during 1984. Significant actions included laws concerning wages, child labor, school attendance, occupational safety and health, working hours, equal employment opportunity, worker privacy, labor relations, private employment agencies, employment and training, plant closings,…

  4. 26 CFR 1.501(c)(5)-1 - Labor, agricultural, and horticultural organizations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 7 2011-04-01 2009-04-01 true Labor, agricultural, and horticultural... Labor, agricultural, and horticultural organizations. (a) The organizations contemplated by section 501... those engaged in such pursuits, the improvement of the grade of their products, and the development of...

  5. 26 CFR 1.501(c)(5)-1 - Labor, agricultural, and horticultural organizations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Labor, agricultural, and horticultural... Labor, agricultural, and horticultural organizations. (a) The organizations contemplated by section 501... those engaged in such pursuits, the improvement of the grade of their products, and the development of...

  6. Migration within the periphery: Haitian labor in the Dominican sugar and coffee industries.

    PubMed

    Grasmuck, S

    1982-01-01

    "This article presents data on the employment of Haitian labor in the sugar and coffee sectors in the Dominican economy. The Haitian cyclical pattern of migration is related to the enclave pattern of development as it has occurred in the Dominican Republic. The common features of both coffee and sugarcane production which stimulate the reliance on cheap foreign labor are discussed." PMID:12312174

  7. Reproducing Life and Labor: Global Processes and Working Children in Tijuana, Mexico

    ERIC Educational Resources Information Center

    Aitken, Stuart; Estrada, Silvia Lopez; Jennings, Joel; Aguirre, Lina Maria

    2006-01-01

    The issue of child labor continues to challenge thinking on the nature of work, play, schooling and apprenticeship. New wisdom from some contemporary academic writing places children closer to the center of our understanding of consumption, production and reproduction, and at the heart of inequities generated by globalization. Child labor comes in…

  8. Not by Labor Alone: Considerations for Value Influence Use of the Labor Rule in Ownership Transfers

    ERIC Educational Resources Information Center

    Kanngiesser, Patricia; Hood, Bruce

    2014-01-01

    People often assign ownership to the person who has invested labor into making an object (labor rule). However, labor usually improves objects and increases their value, and it has not been investigated whether these considerations underlie people's use of the labor rule. We presented participants with third-party ownership conflicts between…

  9. Declining Teen Labor Force Participation. Issues in Labor Statistics. Summary 02-06.

    ERIC Educational Resources Information Center

    Kirkland, Katie

    Although the proportion of teenagers in the labor force generally increases during economic expansions, the labor force participation rate for 16- to 19-year-olds changed very little during the exceptional labor market conditions of the mid-1990s. In July 2000, the labor force participation rate for teens was at its lowest level since 1965.…

  10. Holographic characterization of protein aggregates

    NASA Astrophysics Data System (ADS)

    Wang, Chen; Zhong, Xiao; Ruffner, David; Stutt, Alexandra; Philips, Laura; Ward, Michael; Grier, David

    Holographic characterization directly measures the size distribution of subvisible protein aggregates in suspension and offers insights into their morphology. Based on holographic video microscopy, this analytical technique records and interprets holograms of individual aggregates in protein solutions as they flow down a microfluidic channel, without requiring labeling or other exceptional sample preparation. The hologram of an individual protein aggregate is analyzed in real time with the Lorenz-Mie theory of light scattering to measure that aggregate's size and optical properties. Detecting, counting and characterizing subvisible aggregates proceeds fast enough for time-resolved studies, and lends itself to tracking trends in protein aggregation arising from changing environmental factors. No other analytical technique provides such a wealth of particle-resolved characterization data in situ. Holographic characterization promises accelerated development of therapeutic protein formulations, improved process control during manufacturing, and streamlined quality assurance during storage and at the point of use. Mrsec and MRI program of the NSF, Spheryx Inc.

  11. Military duty: risk factor for preterm labor? A review.

    PubMed

    McNeary, A M; Lomenick, T S

    2000-08-01

    The female military population represents a high-risk group for preterm labor and other adverse pregnancy outcomes. As the number of women entering the armed forces continues to increase, concerns regarding the effects of military service on pregnancy must persist. Although active duty females have access to prenatal care and maintain consistent follow-up, previous research has noted a 5-fold increase in preterm labor compared with civilian working women. Hospitalization and loss of work attributable to pregnancy complications directly affect productivity and mission accomplishment; therefore, it is crucial to identify those at risk to institute measures that will prevent such occurrences and decrease time away from work. This article provides a review of the existing literature concerning preterm labor in military women, comparisons with the civilian population, and recommendations for future research. PMID:10957855

  12. Global work force 2000: the new world labor market.

    PubMed

    Johnston, W B

    1991-01-01

    Just as there are global markets for products, technology, and capital, managers must now think of one for labor. Over the next 15 years, human capital, once the most stationary factor in production, will cross national borders with greater and greater ease. Driving the globalization of labor is a growing imbalance between the world's labor supply and demand. While the developed world accounts for most of the world's gross domestic product, its share of the world work force is shrinking. Meanwhile, in the developing countries, the work force is quickly expanding as many young people approach working age and as women join the paid work force in great numbers. The quality of that work force is also rising as developing countries like Brazil and China generate growing proportions of the world's college graduates. Developing nations that combine their young, educated workers with investor-friendly policies could leapfrog into new industries. South Korea, Taiwan, Poland, and Hungary are particularly well positioned for such growth. And industrialized countries that keep barriers to immigration low will be able to tap world labor resources to sustain their economic growth. The United States and some European nations have the best chance of encouraging immigration, while Japan will have trouble overcoming its cultural and language barriers. PMID:10110172

  13. Aggregates from natural and recycled sources; economic assessments for construction applications; a materials flow study

    USGS Publications Warehouse

    Wilburn, David R.; Goonan, Thomas G.

    1998-01-01

    Increased amounts of recycled materials are being used to supplement natural aggregates (derived from crushed stone, sand and gravel) in road construction. An understanding of the economics and factors affecting the level of aggregates recycling is useful in estimating the potential for recycling and in assessing the total supply picture of aggregates. This investigation includes a descriptive analysis of the supply sources, technology, costs, incentives, deterrents, and market relationships associated with the production of aggregates.

  14. Artificial aggregate made from waste stone sludge and waste silt.

    PubMed

    Chang, Fang-Chih; Lee, Ming-Yu; Lo, Shang-Lien; Lin, Jyh-Dong

    2010-11-01

    In this research, waste stone sludge obtained from slab stone processing and waste silt from aggregate washing plants were recycled to manufacture artificial aggregate. Fine-powdered stone sludge was mixed with waste silt of larger particle size; vibratory compaction was applied for good water permeability, resulting in a smaller amount of solidifying agent being used. For the densified packing used in this study, the mix proportion of waste stone sludge to waste silt was 35:50, which produced artificial aggregate of more compact structure with water absorption rate below 0.1%. In addition, applying vibratory compaction of 33.3 Hz to the artificial aggregate and curing for 28 days doubled the compressive strength to above 29.4 MPa. Hence, recycling of waste stone sludge and waste silt for the production of artificial aggregate not only offers a feasible substitute for sand and stone, but also an ecological alternative to waste management of sludge and silt.

  15. Comparison the Effects of Health Indicators on Male and Female Labor Supply, Evidence from Panel Data of Eastern Mediterranean Countries 1995-2010

    PubMed Central

    HOMAIE RAD, Enayatollah; HADIAN, Mohamad; GHOLAMPOOR, Hanie

    2014-01-01

    Abstract Background Skilled labor force is very important in economic growth. Workers become skilled when they are healthy and able to be educated and work. In this study, we estimated the effects of health indicators on labor supply. We used labor force participation rate as the indicator of labor supply. We categorized this indicator into 2 indicators of female and male labor force participation rates and compared the results of each estimate with the other. Methods This study was done in eastern Mediterranean countries between 1995 and 2011. We used a panel cointegration approach for estimating the models. We used Pesaran cross sectional dependency, Pesaran unit root test, and Westerlund panel cointegration for this issue. At the end, after confirmation of having random effect models, we estimated them with random effects. Results Increasing the fertility rate decreased the female labor supply, but increased the male labor supply. However, public health expenditures increased the female labor supply, but decreased the male labor supply because of substitution effects. Similar results were found regarding urbanization. Gross domestic product had a positive relationship with female labor supply, but not with male labor supply. Besides, out of pocket health expenditures had a negative relationship with male labor supply, but no significant relationships with female labor supply. Conclusion The effects of the health variables were more severe in the female labor supply model compared to the male model. Countries must pay attention to women’s health more and more to change the labor supply. PMID:26060746

  16. Cis-Suppression to Arrest Protein Aggregation in Mammalian Cells

    PubMed Central

    Gregoire, Simpson; Zhang, Shaojie; Costanzo, Joseph; Wilson, Kelly; Fernandez, Erik J.; Kwon, Inchan

    2015-01-01

    Protein misfolding and aggregation are implicated in numerous human diseases and significantly lower production yield of proteins expressed in mammalian cells. Despite the importance of understanding and suppressing protein aggregation in mammalian cells, a protein design and selection strategy to modulate protein misfolding/aggregation in mammalian cells has not yet been reported. In this work, we address the particular challenge presented by mutation-induced protein aggregation in mammalian cells. We hypothesize that an additional mutation(s) can be introduced in an aggregation-prone protein variant, spatially near the original mutation, to suppress misfolding and aggregation (cis-suppression). As a model protein, we chose human copper, zinc superoxide dismutase mutant (SOD1A4V) containing an alanine to valine mutation at residue 4, associated with the familial form of amyotrophic lateral sclerosis. We used the program RosettaDesign to identify Phe20 in SOD1A4V as a key residue responsible for SOD1A4V conformational destabilization. This information was used to rationally develop a pool of candidate mutations at the Phe20 site. After two rounds of mammalian-cell based screening of the variants, three novel SOD1A4V variants with a significantly reduced aggregation propensity inside cells were selected. The enhanced stability and reduced aggregation propensity of the three novel SOD1A4V variants were verified using cell fractionation and in vitro stability assays. PMID:24114411

  17. Reduction in soil aggregation in response to dust emission processes

    NASA Astrophysics Data System (ADS)

    Swet, Nitzan; Katra, Itzhak

    2016-09-01

    Dust emission by aeolian (wind) soil erosion depends on the topsoil properties of the source area, especially on the nature of the aggregates where most dust particles are held. Although the key role of soil aggregates in dust emission, the response of soil aggregation to aeolian processes and its implications for dust emission remain unknown. This study focuses on aggregate size distribution (ASD) analyses before and after in-situ aeolian experiments in semiarid loess soils that are associated with dust emission. Wind tunnel simulations show that particulate matter (PM) emission and saltation rates depend on the initial ASD and shear velocity. Under all initial ASD conditions, the content of saltator-sized aggregates (63-250 μm) increased by 10-34% due to erosion of macro-aggregates (> 500 μm), resulting in a higher size ratio (SR) between the saltators and macro-aggregates following the aeolian erosion. The results revealed that the saltator production increases significantly for soils that are subjected to short-term (anthropogenic) disturbance of the topsoil. The findings highlight a decrease in soil aggregation for all initial ASD's in response to aeolian erosion, and consequently its influence on the dust emission potential. Changes in ASD should be considered as a key parameter in dust emission models of complex surfaces.

  18. Floating Ice-Algal Aggregates below Melting Arctic Sea Ice

    PubMed Central

    Assmy, Philipp; Ehn, Jens K.; Fernández-Méndez, Mar; Hop, Haakon; Katlein, Christian; Sundfjord, Arild; Bluhm, Katrin; Daase, Malin; Engel, Anja; Fransson, Agneta; Granskog, Mats A.; Hudson, Stephen R.; Kristiansen, Svein; Nicolaus, Marcel; Peeken, Ilka; Renner, Angelika H. H.; Spreen, Gunnar; Tatarek, Agnieszka; Wiktor, Jozef

    2013-01-01

    During two consecutive cruises to the Eastern Central Arctic in late summer 2012, we observed floating algal aggregates in the melt-water layer below and between melting ice floes of first-year pack ice. The macroscopic (1-15 cm in diameter) aggregates had a mucous consistency and were dominated by typical ice-associated pennate diatoms embedded within the mucous matrix. Aggregates maintained buoyancy and accumulated just above a strong pycnocline that separated meltwater and seawater layers. We were able, for the first time, to obtain quantitative abundance and biomass estimates of these aggregates. Although their biomass and production on a square metre basis was small compared to ice-algal blooms, the floating ice-algal aggregates supported high levels of biological activity on the scale of the individual aggregate. In addition they constituted a food source for the ice-associated fauna as revealed by pigments indicative of zooplankton grazing, high abundance of naked ciliates, and ice amphipods associated with them. During the Arctic melt season, these floating aggregates likely play an important ecological role in an otherwise impoverished near-surface sea ice environment. Our findings provide important observations and measurements of a unique aggregate-based habitat during the 2012 record sea ice minimum year. PMID:24204642

  19. Floating ice-algal aggregates below melting arctic sea ice.

    PubMed

    Assmy, Philipp; Ehn, Jens K; Fernández-Méndez, Mar; Hop, Haakon; Katlein, Christian; Sundfjord, Arild; Bluhm, Katrin; Daase, Malin; Engel, Anja; Fransson, Agneta; Granskog, Mats A; Hudson, Stephen R; Kristiansen, Svein; Nicolaus, Marcel; Peeken, Ilka; Renner, Angelika H H; Spreen, Gunnar; Tatarek, Agnieszka; Wiktor, Jozef

    2013-01-01

    During two consecutive cruises to the Eastern Central Arctic in late summer 2012, we observed floating algal aggregates in the melt-water layer below and between melting ice floes of first-year pack ice. The macroscopic (1-15 cm in diameter) aggregates had a mucous consistency and were dominated by typical ice-associated pennate diatoms embedded within the mucous matrix. Aggregates maintained buoyancy and accumulated just above a strong pycnocline that separated meltwater and seawater layers. We were able, for the first time, to obtain quantitative abundance and biomass estimates of these aggregates. Although their biomass and production on a square metre basis was small compared to ice-algal blooms, the floating ice-algal aggregates supported high levels of biological activity on the scale of the individual aggregate. In addition they constituted a food source for the ice-associated fauna as revealed by pigments indicative of zooplankton grazing, high abundance of naked ciliates, and ice amphipods associated with them. During the Arctic melt season, these floating aggregates likely play an important ecological role in an otherwise impoverished near-surface sea ice environment. Our findings provide important observations and measurements of a unique aggregate-based habitat during the 2012 record sea ice minimum year.

  20. 20 CFR 656.26 - Board of Alien Labor Certification Appeals review of denials of labor certification.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... TRAINING ADMINISTRATION, DEPARTMENT OF LABOR LABOR CERTIFICATION PROCESS FOR PERMANENT EMPLOYMENT OF ALIENS IN THE UNITED STATES Labor Certification Process § 656.26 Board of Alien Labor Certification...

  1. Peptide aggregation in neurodegenerative disease.

    PubMed

    Murphy, Regina M

    2002-01-01

    In the not-so-distant past, insoluble aggregated protein was considered as uninteresting and bothersome as yesterday's trash. More recently, protein aggregates have enjoyed considerable scientific interest, as it has become clear that these aggregates play key roles in many diseases. In this review, we focus attention on three polypeptides: beta-amyloid, prion, and huntingtin, which are linked to three feared neurodegenerative diseases: Alzheimer's, "mad cow," and Huntington's disease, respectively. These proteins lack any significant primary sequence homology, yet their aggregates possess very similar features, specifically, high beta-sheet content, fibrillar morphology, relative insolubility, and protease resistance. Because the aggregates are noncrystalline, secrets of their structure at nanometer resolution are only slowly yielding to X-ray diffraction, solid-state NMR, and other techniques. Besides structure, the aggregates may possess similar pathways of assembly. Two alternative assembly pathways have been proposed: the nucleation-elongation and the template-assisted mode. These two modes may be complementary, not mutually exclusive. Strategies for interfering with aggregation, which may provide novel therapeutic approaches, are under development. The structural similarities between protein aggregates of dissimilar origin suggest that therapeutic strategies successful against one disease may have broad utility in others. PMID:12117755

  2. Topics in Probabilistic Judgment Aggregation

    ERIC Educational Resources Information Center

    Wang, Guanchun

    2011-01-01

    This dissertation is a compilation of several studies that are united by their relevance to probabilistic judgment aggregation. In the face of complex and uncertain events, panels of judges are frequently consulted to provide probabilistic forecasts, and aggregation of such estimates in groups often yield better results than could have been made…

  3. Mineral of the month: aggregates

    USGS Publications Warehouse

    Tepordei, Valentin V.

    2005-01-01

    Natural aggregates, consisting of crushed stone, and sand and gravel, are a major contributor to economic health, and have an amazing variety of uses. Aggregates are among the most abundant mineral resources and are major basic raw materials used by construction, agriculture and other industries that employ complex chemical and metallurgical processes.

  4. 29 CFR 42.9 - Farm Labor Specialist (ESA).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 1 2012-07-01 2012-07-01 false Farm Labor Specialist (ESA). 42.9 Section 42.9 Labor Office of the Secretary of Labor COORDINATED ENFORCEMENT § 42.9 Farm Labor Specialist (ESA). (a) The Assistant Secretary for ESA shall designate ESA Compliance Officers as Farm Labor Specialists...

  5. 29 CFR 42.9 - Farm Labor Specialist (ESA).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Farm Labor Specialist (ESA). 42.9 Section 42.9 Labor Office of the Secretary of Labor COORDINATED ENFORCEMENT § 42.9 Farm Labor Specialist (ESA). (a) The Assistant Secretary for ESA shall designate ESA Compliance Officers as Farm Labor Specialists...

  6. 29 CFR 42.9 - Farm Labor Specialist (ESA).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 1 2013-07-01 2013-07-01 false Farm Labor Specialist (ESA). 42.9 Section 42.9 Labor Office of the Secretary of Labor COORDINATED ENFORCEMENT § 42.9 Farm Labor Specialist (ESA). (a) The Assistant Secretary for ESA shall designate ESA Compliance Officers as Farm Labor Specialists...

  7. 29 CFR 42.9 - Farm Labor Specialist (ESA).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Farm Labor Specialist (ESA). 42.9 Section 42.9 Labor Office of the Secretary of Labor COORDINATED ENFORCEMENT § 42.9 Farm Labor Specialist (ESA). (a) The Assistant Secretary for ESA shall designate ESA Compliance Officers as Farm Labor Specialists...

  8. 29 CFR 42.9 - Farm Labor Specialist (ESA).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Farm Labor Specialist (ESA). 42.9 Section 42.9 Labor Office of the Secretary of Labor COORDINATED ENFORCEMENT § 42.9 Farm Labor Specialist (ESA). (a) The Assistant Secretary for ESA shall designate ESA Compliance Officers as Farm Labor Specialists...

  9. Molecular aggregation of humic substances

    USGS Publications Warehouse

    Wershaw, R. L.

    1999-01-01

    Humic substances (HS) form molecular aggregates in solution and on mineral surfaces. Elucidation of the mechanism of formation of these aggregates is important for an understanding of the interactions of HS in soils arid natural waters. The HS are formed mainly by enzymatic depolymerization and oxidation of plant biopolymers. These reactions transform the aromatic and lipid plant components into amphiphilic molecules, that is, molecules that consist of separate hydrophobic (nonpolar) and hydrophilic (polar) parts. The nonpolar parts of the molecules are composed of relatively unaltered segments of plant polymers and the polar parts of carboxylic acid groups. These amphiphiles form membrane-like aggregates on mineral surfaces and micelle-like aggregates in solution. The exterior surfaces of these aggregates are hydrophilic, and the interiors constitute separate hydrophobic liquid-like phases.

  10. Nanoparticle aggregation: principles and modeling.

    PubMed

    Zhang, Wen

    2014-01-01

    The high surface area to volume ratio of nanoparticles usually results in highly reactive and colloidal instability compared to their bulk counterparts. Aggregation as well as many other transformations (e.g., dissolution) in the environment may alter the physiochemical properties, reactivity, fate, transport, and biological interactions (e.g., bioavailability and uptake) of nanoparticles. The unique properties pertinent to nanoparticles, such as shape, size, surface characteristics, composition, and electronic structures, greatly challenge the ability of colloid science to understand nanoparticle aggregation and its environmental impacts. This review briefly introduces fundamentals about aggregation, fractal dimensions, classic and extended Derjaguin-Landau-Verwey-Overbeak (DLVO) theories, aggregation kinetic modeling, experimental measurements, followed by detailed discussions on the major factors on aggregation and subsequent effects on nanomaterial transport and reactivity.

  11. Mechanics of fire ant aggregations

    NASA Astrophysics Data System (ADS)

    Tennenbaum, Michael; Liu, Zhongyang; Hu, David; Fernandez-Nieves, Alberto

    2016-01-01

    Fire ants link their bodies to form aggregations; these can adopt a variety of structures, they can drip and spread, or withstand applied loads. Here, by using oscillatory rheology, we show that fire ant aggregations are viscoelastic. We find that, at the lowest ant densities probed and in the linear regime, the elastic and viscous moduli are essentially identical over the spanned frequency range, which highlights the absence of a dominant mode of structural relaxation. As ant density increases, the elastic modulus rises, which we interpret by alluding to ant crowding and subsequent jamming. When deformed beyond the linear regime, the aggregation flows, exhibiting shear-thinning behaviour with a stress load that is comparable to the maximum load the aggregation can withstand before individual ants are torn apart. Our findings illustrate the rich, collective mechanical behaviour that can arise in aggregations of active, interacting building blocks.

  12. Mechanics of fire ant aggregations.

    PubMed

    Tennenbaum, Michael; Liu, Zhongyang; Hu, David; Fernandez-Nieves, Alberto

    2016-01-01

    Fire ants link their bodies to form aggregations; these can adopt a variety of structures, they can drip and spread, or withstand applied loads. Here, by using oscillatory rheology, we show that fire ant aggregations are viscoelastic. We find that, at the lowest ant densities probed and in the linear regime, the elastic and viscous moduli are essentially identical over the spanned frequency range, which highlights the absence of a dominant mode of structural relaxation. As ant density increases, the elastic modulus rises, which we interpret by alluding to ant crowding and subsequent jamming. When deformed beyond the linear regime, the aggregation flows, exhibiting shear-thinning behaviour with a stress load that is comparable to the maximum load the aggregation can withstand before individual ants are torn apart. Our findings illustrate the rich, collective mechanical behaviour that can arise in aggregations of active, interacting building blocks. PMID:26501413

  13. Adsorption-induced colloidal aggregation

    NASA Astrophysics Data System (ADS)

    Law, B. M.; Petit, J.-M.; Beysens, D.

    1998-03-01

    Reversible colloidal aggregation in binary liquid mixtures has been studied for a number of years. As the phase separation temperature of the liquid mixture is approached the thickness of an adsorption layer around the colloidal particles increases. Beysens and coworkers have demonstrated experimentally that this adsorption layer is intimately connected with the aggregation of the colloidal particles, however, no definitive theory has been available which can explain all of the experimental observations. In this contribution we describe an extension of the Derjaguin, Landau, Verwey, and Overbeek theory of colloidal aggregation which takes into account the presence of the adsorption layer and which more realistically models the attractive dispersion interactions. This modified theory can quantitatively account for many of the observed experimental features such as the characteristics of the aggregated state, the general shape of the aggregation line, and the temperature dependence of the second virial coefficient for a lutidine-water mixture containing a small volume fraction of silica colloidal particles.

  14. A global perspective on foreign contract labor.

    PubMed

    Smart, J E; Casco, R R

    1988-01-01

    This paper provides a general overview on foreign contract labor. The growth in the use of foreign contract labor is described with reference to other types of international labor movements such as 1) illegal, undocumented, or irregular migration; 2) free migration; and 3) permanent settlement migration. Within this general context, the various national advantages and disadvantages of contract labor are outlined. Particular issues like the role of trade unions and the likely future international labor circulation are noted. The 1984 World Labour Report estimates a global stock of almost 22 million foreign workers. Despite lack of reliable data, the size of irregular labor flows is considerable. More than 4 million undocumented workers, primarily Mexicans, can be found in the US alone. Other major flows of illegal labor go from China to Hong Kong, Malaysia to Singapore, Columbia to Venezuela, and poor Arab countries to oil-exporting countries in the Middle East. Laws are often poorly enforced and contradictory. Employers often actively recruit illegal migrants. While permanent migration was formerly the primary source of foreign workers, the numbers migrating in this manner are decreasing significantly. In absolute terms, host countries gain considerably more through the use of contract labor than sending countries. The pervasive commitment of national governments to economic growth is a prime consideration in the decision to import foreign labor. In general, trade unions have created an environment wherein the use of foreign labor in the formal as opposed to the informal labor market is more difficult. The disadvantages of labor export include the costs of family separation, worker exploitation, and cultural alienation. Remittances constitute the most tangible return of labor export. In many countries they have made a very considerable impact on the balance of payments deficit.

  15. A global perspective on foreign contract labor.

    PubMed

    Smart, J E; Casco, R R

    1988-01-01

    This paper provides a general overview on foreign contract labor. The growth in the use of foreign contract labor is described with reference to other types of international labor movements such as 1) illegal, undocumented, or irregular migration; 2) free migration; and 3) permanent settlement migration. Within this general context, the various national advantages and disadvantages of contract labor are outlined. Particular issues like the role of trade unions and the likely future international labor circulation are noted. The 1984 World Labour Report estimates a global stock of almost 22 million foreign workers. Despite lack of reliable data, the size of irregular labor flows is considerable. More than 4 million undocumented workers, primarily Mexicans, can be found in the US alone. Other major flows of illegal labor go from China to Hong Kong, Malaysia to Singapore, Columbia to Venezuela, and poor Arab countries to oil-exporting countries in the Middle East. Laws are often poorly enforced and contradictory. Employers often actively recruit illegal migrants. While permanent migration was formerly the primary source of foreign workers, the numbers migrating in this manner are decreasing significantly. In absolute terms, host countries gain considerably more through the use of contract labor than sending countries. The pervasive commitment of national governments to economic growth is a prime consideration in the decision to import foreign labor. In general, trade unions have created an environment wherein the use of foreign labor in the formal as opposed to the informal labor market is more difficult. The disadvantages of labor export include the costs of family separation, worker exploitation, and cultural alienation. Remittances constitute the most tangible return of labor export. In many countries they have made a very considerable impact on the balance of payments deficit. PMID:12281042

  16. Korean Emotional Laborers' Job Stressors and Relievers: Focus on Work Conditions and Emotional Labor Properties

    PubMed Central

    Lee, Garam

    2015-01-01

    Background The present study aims to investigate job stressors and stress relievers for Korean emotional laborers, specifically focusing on the effects of work conditions and emotional labor properties. Emotional laborers are asked to hide or distort their real emotions in their interaction with clients. They are exposed to high levels of stress in the emotional labor process, which leads to serious mental health risks including burnout, depression, and even suicide impulse. Exploring job stressors and relieving factors would be the first step in seeking alternatives to protect emotional laborers from those mental health risks. Methods Using the third wave data of Korean Working Conditions Survey, logistic regression analysis was conducted for two purposes: to examine the relations of emotional labor and stress, and to find out job stressors and relievers for emotional laborers. Results The chances of stress arousal are 3.5 times higher for emotional laborers; emotional laborers experience double risk-burden for stress arousal. In addition to general job stressors, emotional laborers need to bear burdens related to emotional labor properties. The effect of social support at the workplace is not significant for stress relief, unlike common assumptions, whereas subjective satisfaction (wage satisfaction and work-life balance) is proven to have relieving effects on emotional laborers' job stress. Conclusion From the results, the importance of a balanced understanding of emotional labor for establishing effective policies for emotional laborer protection is stressed. PMID:26929847

  17. Engineering a Fibrocartilage Spectrum Through Modulation of Aggregate Redifferentiation

    PubMed Central

    Murphy, Meghan K.; Masters, Taylor E.; Hu, Jerry C.; Athanasiou, Kyriacos A.

    2015-01-01

    Expanded costochondral cells provide a clinically relevant cell source for engineering both fibrous and hyaline articular cartilage. Expanding chondrocytes in monolayer results in a shift toward a proliferative, fibroblastic phenotype. Three-dimensional aggregate culture may, however, be used to recover chondrogenic matrix production. This study sought to engineer a spectrum of fibrous to hyaline neocartilage from a single cell source by varying the duration of three-dimensional culture following expansion. In third passage porcine costochondral cells, the effects of aggregate culture duration were assessed after 0, 8, 11, 14, and 21 days of aggregate culture and after 4 subsequent weeks of neocartilage formation. Varying the duration of aggregate redifferentiation generated a spectrum of fibrous to hyaline neocartilage. Within 8 days of aggregation, proliferation ceased, and collagen and glycosaminoglycan production increased, compared with monolayer cells. In self-assembled neocartilage, type II to I collagen ratio increased with increasing aggregate duration, yet glycosaminoglycan content varied minimally. Notably, 14 days of aggregate redifferentiation increased collagen content by 25%, tensile modulus by over 110%, and compressive moduli by over 50%, compared with tissue formed in the absence of redifferentiation. A spectrum of fibrous to hyaline cartilage was generated using a single, clinically relevant cell source, improving the translational potential of engineered cartilage. PMID:24380383

  18. Sequence determinants of protein aggregation: tools to increase protein solubility

    PubMed Central

    Ventura, Salvador

    2005-01-01

    Escherichia coli is one of the most widely used hosts for the production of recombinant proteins. However, very often the target protein accumulates into insoluble aggregates in a misfolded and biologically inactive form. Bacterial inclusion bodies are major bottlenecks in protein production and are hampering the development of top priority research areas such structural genomics. Inclusion body formation was formerly considered to occur via non-specific association of hydrophobic surfaces in folding intermediates. Increasing evidence, however, indicates that protein aggregation in bacteria resembles to the well-studied process of amyloid fibril formation. Both processes appear to rely on the formation of specific, sequence-dependent, intermolecular interactions driving the formation of structured protein aggregates. This similarity in the mechanisms of aggregation will probably allow applying anti-aggregational strategies already tested in the amyloid context to the less explored area of protein aggregation inside bacteria. Specifically, new sequence-based approaches appear as promising tools to tune protein aggregation in biotechnological processes. PMID:15847694

  19. 75 FR 11512 - Consultative Group to Eliminate the Use of Child Labor and Forced Labor in Imported Agricultural...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-11

    ... Foreign Agricultural Service Consultative Group to Eliminate the Use of Child Labor and Forced Labor in... public meeting of the Consultative Group to Eliminate the Use of Child Labor and Forced Labor in Imported... forced labor or child labor. The notice sets forth the process for requesting to appear at the...

  20. Protecting labor rights: roles for public health.

    PubMed

    Bhatia, Rajiv; Gaydos, Megan; Yu, Karen; Weintraub, June

    2013-11-01

    Federal, state, and local labor laws establish minimum standards for working conditions, including wages, work hours, occupational safety, and collective bargaining. The adoption and enforcement of labor laws protect and promote social, economic, and physical determinants of health, while incomplete compliance undermines these laws and contributes to health inequalities. Using existing legal authorities, some public health agencies may be able to contribute to the adoption, monitoring, and enforcement of labor laws. We describe how routine public health functions have been adapted in San Francisco, California, to support compliance with minimum wage and workers' compensation insurance standards. Based on these experiences, we consider the opportunities and obstacles for health agencies to defend and advance labor standards. Increasing coordinated action between health and labor agencies may be a promising approach to reducing health inequities and efficiently enforcing labor standards.

  1. AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides

    PubMed Central

    Conchillo-Solé, Oscar; de Groot, Natalia S; Avilés, Francesc X; Vendrell, Josep; Daura, Xavier; Ventura, Salvador

    2007-01-01

    Background Protein aggregation correlates with the development of several debilitating human disorders of growing incidence, such as Alzheimer's and Parkinson's diseases. On the biotechnological side, protein production is often hampered by the accumulation of recombinant proteins into aggregates. Thus, the development of methods to anticipate the aggregation properties of polypeptides is receiving increasing attention. AGGRESCAN is a web-based software for the prediction of aggregation-prone segments in protein sequences, the analysis of the effect of mutations on protein aggregation propensities and the comparison of the aggregation properties of different proteins or protein sets. Results AGGRESCAN is based on an aggregation-propensity scale for natural amino acids derived from in vivo experiments and on the assumption that short and specific sequence stretches modulate protein aggregation. The algorithm is shown to identify a series of protein fragments involved in the aggregation of disease-related proteins and to predict the effect of genetic mutations on their deposition propensities. It also provides new insights into the differential aggregation properties displayed by globular proteins, natively unfolded polypeptides, amyloidogenic proteins and proteins found in bacterial inclusion bodies. Conclusion By identifying aggregation-prone segments in proteins, AGGRESCAN shall facilitate (i) the identification of possible therapeutic targets for anti-depositional strategies in conformational diseases and (ii) the anticipation of aggregation phenomena during storage or recombinant production of bioactive polypeptides or polypeptide sets. PMID:17324296

  2. 29 CFR 779.13 - Production.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Production. 779.13 Section 779.13 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR..., manufacturing, mining, handling, transporting, or in any other manner working on such goods, or in any...

  3. 29 CFR 779.13 - Production.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Production. 779.13 Section 779.13 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR..., manufacturing, mining, handling, transporting, or in any other manner working on such goods, or in any...

  4. 29 CFR 779.13 - Production.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Production. 779.13 Section 779.13 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR..., manufacturing, mining, handling, transporting, or in any other manner working on such goods, or in any...

  5. Physician Labor Market in Croatia

    PubMed Central

    Bagat, Mario; Sekelj Kauzlarić, Katarina

    2006-01-01

    Aim To analyze the physician labor market in Croatia with respect to the internship and employment opportunities, Croatian needs for physicians and specialists, and trends in physician labor market in the European Union (EU) in the context of EU enlargement. Methods Data were collected from the Ministry of Health and Social Welfare, the Croatian Employment Service, and the Croatian Institute for Public Health. We compared the number of physicians waiting for internship before and 14 months after the implementation of the State Program for Intern Employment Stimulation. Also, the number of employed specialists in internal medicine, general surgery, gynecology and obstetrics, and pediatrics was compared with estimated number of specialists that will have been needed by the end of 2007. Average age of hospital physicians in the four specialties was determined and the number of Croatian physicians compared with the number of physicians in EU countries. Results The number of unemployed physicians waiting for internship decreased from 335 in 2003 to 82 in 2004, while a total number of unemployed physicians decreased from 436 to 379 (χ2 = 338, P<0.001). In October 2004, 79.3% of unemployed physicians waited for internship <6 months; of them, 89.2% waited for internship <3 months. In February 2005, 365 unemployed physicians were registered at the Croatian Employment Service and that number has been decreasing in the last couple of years. The number of employed specialists was lower than the estimated number of specialists needed in the analyzed specialists, as defined by the prescribed standards. A shortage of 328 internists, 319 surgeons, 209 gynecologists, and 69 pediatricians in Croatian hospitals is expected in 2007. Conclusion The lack of employment incentive seems to be the main reason for the large number of unemployed physicians waiting for internship before the implementation of the Employment Stimulation Program. According to the number of physicians per 100

  6. Genetic contributions to labor pain and progress.

    PubMed

    Landau, Ruth

    2013-09-01

    Studies on genetic contributions to labor analgesia have essentially evaluated the μ-opioid receptor gene (OPRM1), with some evidence that p.118A/G of OPRM1 influences the response to neuraxial opioids. As for labor progress, the β2-adrenergic receptor gene (ADRB2) is associated with preterm labor and delivery, and impacts the course of labor. Taken together though, there is no evidence that pharmacogenetic testing is needed or beneficial in the context of obstetric anesthesia; however, realizing the influence of genetic variants on specific phenotypes provides the rationale for a more cautious interpretation of clinical studies that attempt to find a dose-regimen that fits all.

  7. ';Best' Practices for Aggregating Subset Results from Archived Datasets

    NASA Astrophysics Data System (ADS)

    Baskin, W. E.; Perez, J.

    2013-12-01

    In response to the exponential growth in science data analysis and visualization capabilities Data Centers have been developing new delivery mechanisms to package and deliver large volumes of aggregated subsets of archived data. New standards are evolving to help data providers and application programmers deal with growing needs of the science community. These standards evolve from the best practices gleaned from new products and capabilities. The NASA Atmospheric Sciences Data Center (ASDC) has developed and deployed production provider-specific search and subset web applications for the CALIPSO, CERES, TES, and MOPITT missions. This presentation explores several use cases that leverage aggregated subset results and examines the standards and formats ASDC developers applied to the delivered files as well as the implementation strategies for subsetting and processing the aggregated products. The following topics will be addressed: - Applications of NetCDF CF conventions to aggregated level 2 satellite subsets - Data-Provider-Specific format requirements vs. generalized standards - Organization of the file structure of aggregated NetCDF subset output - Global Attributes of individual subsetted files vs. aggregated results - Specific applications and framework used for subsetting and delivering derivative data files

  8. Proportionate mortality among construction laborers.

    PubMed

    Stern, F; Schulte, P; Sweeney, M H; Fingerhut, M; Vossenas, P; Burkhardt, G; Kornak, M F

    1995-04-01

    This report presents the results of proportionate mortality ratio (PMR) analyses and proportionate cancer mortality ratio (PCMR) analyses among the 11,685 members of the Laborers' International Union of North America (LIUNA), who died between 1985-1988, using U.S. proportionate mortality rates as the comparison population. Statistically significant elevated mortality risks were observed for all malignant neoplasms (N = 3285, PMR = 1.13, CI = 1.09-1.17), as well as for site-specific neoplasms of the lung (N = 1208, PCMR = 1.06, CI = 1.00-1.12), stomach (N = 170, PCMR = 1.44, CI = 1.23-1.68), and thyroid gland (N = 10, PCMR = 2.24, CI = 1.07-4.12). The PCMRs for these malignant neoplasms were elevated among both white and non-white males, regardless of length of union membership, in most 10-year categories of age at death above 40 and for the three largest LIUNA regions examined. The study also observed 20 mesothelioma deaths, which indicated that some LIUNA members had been previously exposed to asbestos. Statistically significant elevated risks were also observed for deaths from transportation injuries (N = 448, PMR = 1.37, CI = 1.25-1.51), falls (N = 85, PMR = 1.34, CI = 1.07-1.66), and other types of injuries (N = 245, PMR = 1.61, CI = 1.42-1.83). The deaths due to injuries were most often observed among those members who had the shortest amount of time within the union, were younger, and first entered the union after 1955. This is the first study that has examined the general mortality experience limited to construction laborers only (Bureau of Census code 869).

  9. 76 FR 28730 - Notice of Intent To Suspend the Agricultural Labor Survey and Farm Labor Reports

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-18

    ... National Agricultural Statistics Service Notice of Intent To Suspend the Agricultural Labor Survey and Farm Labor Reports AGENCY: National Agricultural Statistics Service, USDA. ACTION: Notice of suspension of data collection and publication. SUMMARY: This notice announces the intention of the...

  10. Labor force status transitions at older ages in the Philippines, Singapore, Taiwan, and Thailand, 1970-1990.

    PubMed

    Raymo, J M; Cornman, J C

    1999-09-01

    While there is considerable evidence of a trend toward earlier retirement in the United States and Europe, trends in rapidly growing economies in other parts of the world have not been closely examined. This paper traces the labor force participation rates of older men and women in four Asian countries, the Philippines, Singapore, Taiwan, and Thailand, over the period of 1970 to 1990. Aggregate census data are used to calculate net transitions into and out of the labor force so as to permit the analysis of differences by country and cohort as well as change over time. Results show that, although men exhibit a general trend toward earlier net labor force exit, labor force participation rates at older ages remain high. Older women are found to be increasingly engaged in economic activity, especially in Singapore and Taiwan.

  11. 78 FR 13897 - Bureau of International Labor Affairs; Office of Trade and Labor Affairs; Labor Affairs Council...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-01

    ... Affairs Council of the United States-Korea Free Trade Agreement; Notice of Public Session Meeting AGENCY.... ADDRESSES: The LAC will meet at the U.S. Department of Labor, 200 Constitution Avenue NW., Washington, DC... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR......

  12. The nation’s top 25 construction aggregates producers

    USGS Publications Warehouse

    Willett, Jason C.

    2014-01-01

    U.S. production of construction aggregates in 2012 was 2.18 billion short tons valued at $17.6 billion, free on board (f.o.b.) at plant. In 2012, construction aggregates production remained virtually unchanged from the levels of the last two years because of a very slight increase compared with that of 2011 in the production of both construction sand and gravel and crushed stone. The average unit value, which is the f.o.b. at the plant price of a metric ton of material, increased slightly. Construction aggregates production was 36 percent less than and the associated value was 23 percent less than the record highs reported in 2006.

  13. Surface fractals in liposome aggregation.

    PubMed

    Roldán-Vargas, Sándalo; Barnadas-Rodríguez, Ramon; Quesada-Pérez, Manuel; Estelrich, Joan; Callejas-Fernández, José

    2009-01-01

    In this work, the aggregation of charged liposomes induced by magnesium is investigated. Static and dynamic light scattering, Fourier-transform infrared spectroscopy, and cryotransmission electron microscopy are used as experimental techniques. In particular, multiple intracluster scattering is reduced to a negligible amount using a cross-correlation light scattering scheme. The analysis of the cluster structure, probed by means of static light scattering, reveals an evolution from surface fractals to mass fractals with increasing magnesium concentration. Cryotransmission electron microscopy micrographs of the aggregates are consistent with this interpretation. In addition, a comparative analysis of these results with those previously reported in the presence of calcium suggests that the different hydration energy between lipid vesicles when these divalent cations are present plays a fundamental role in the cluster morphology. This suggestion is also supported by infrared spectroscopy data. The kinetics of the aggregation processes is also analyzed through the time evolution of the mean diffusion coefficient of the aggregates. PMID:19257067

  14. Surface fractals in liposome aggregation.

    PubMed

    Roldán-Vargas, Sándalo; Barnadas-Rodríguez, Ramon; Quesada-Pérez, Manuel; Estelrich, Joan; Callejas-Fernández, José

    2009-01-01

    In this work, the aggregation of charged liposomes induced by magnesium is investigated. Static and dynamic light scattering, Fourier-transform infrared spectroscopy, and cryotransmission electron microscopy are used as experimental techniques. In particular, multiple intracluster scattering is reduced to a negligible amount using a cross-correlation light scattering scheme. The analysis of the cluster structure, probed by means of static light scattering, reveals an evolution from surface fractals to mass fractals with increasing magnesium concentration. Cryotransmission electron microscopy micrographs of the aggregates are consistent with this interpretation. In addition, a comparative analysis of these results with those previously reported in the presence of calcium suggests that the different hydration energy between lipid vesicles when these divalent cations are present plays a fundamental role in the cluster morphology. This suggestion is also supported by infrared spectroscopy data. The kinetics of the aggregation processes is also analyzed through the time evolution of the mean diffusion coefficient of the aggregates.

  15. Phosphogypsum slag aggregate-based asphaltic concrete mixes

    SciTech Connect

    Foxworthy, P.T.; Nadimpalli, R.S.; Seals, R.K.

    1996-07-01

    Phosphogypsum is a by-product from the production of phosphoric acid used in the fertilizer and chemical industries. Large production rates and problems associated with its stockpiling have led researchers to seek alternative uses for phosphogypsum, primarily as a construction material. One such use is the extraction of sulfur dioxide for the production of sulfuric acid, a process that also generates a by-product slag aggregate. This study investigated the feasibility of using this slag aggregate in asphaltic concrete binder course mixes. The physical properties of the slag aggregate, such as gradation, specific gravity, absorption, unit weight, and void content, were determined, as well as its durability and environmental characteristics. The Marshall mix design method was used to obtain the optimum asphalt content for this aggregate, while moisture susceptibility was examined using the boiling and modified Lottman tests. Indirect tensile, resilient modulus, and dynamic creep tests were performed on the mix to evaluate its performance potential. The results of the study indicate that phosphogypsum-based slag aggregate can be successfully employed in asphaltic concrete binder course mixtures.

  16. Labor and skills gap analysis of the biomedical research workforce.

    PubMed

    Mason, Julie L; Johnston, Elizabeth; Berndt, Sam; Segal, Katie; Lei, Ming; Wiest, Jonathan S

    2016-08-01

    The United States has experienced an unsustainable increase of the biomedical research workforce over the past 3 decades. This expansion has led to a myriad of consequences, including an imbalance in the number of researchers and available tenure-track faculty positions, extended postdoctoral training periods, increasing age of investigators at first U.S. National Institutes of Health R01 grant, and exodus of talented individuals seeking careers beyond traditional academe. Without accurate data on the biomedical research labor market, challenges will remain in resolving these problems and in advising trainees of viable career options and the skills necessary to be productive in their careers. We analyzed workforce trends, integrating both traditional labor market information and real-time job data. We generated a profile of the current biomedical research workforce, performed labor gap analyses of occupations in the workforce at regional and national levels, and assessed skill transferability between core and complementary occupations. We conclude that although supply into the workforce and the number of job postings for occupations within that workforce have grown over the past decade, supply continues to outstrip demand. Moreover, we identify practical skill sets from real-time job postings to optimally equip trainees for an array of careers to effectively meet future workforce demand.-Mason, J. L., Johnston, E., Berndt, S., Segal, K., Lei, M., Wiest, J. S. Labor and skills gap analysis of the biomedical research workforce.

  17. Valuing human leptospirosis prevention using the opportunity cost of labor.

    PubMed

    Arbiol, Joseph; Borja, Maridel; Yabe, Mitsuyasu; Nomura, Hisako; Gloriani, Nina; Yoshida, Shin-ichi

    2013-05-01

    Leptospirosis is a serious public health concern in the Philippines, not only because of its increasing incidence rate, but also because of its significant health and economic impacts. Despite its relatively high seroprevalence, knowledge on the economic burden of disease, particularly on the value that the society places on disease prevention remains limited. Obtaining such information is important within the context of public health policy. This study was conducted in Metro Manila to determine the economic burden of leptospirosis, by asking respondents about their willingness to contribute to labor (WTCL) for the prevention of leptospirosis. The respondents pledged an average labor contribution of 10.66 h/month. The average WTCL corresponded to a monetary value of US$4.01 per month when valued using the opportunity cost of labor (leisure rate of time). From the monetized labor contribution, the total economic value of preventing leptospirosis was estimated at US$124.97 million per annum, which represents 1.13% of Metro Manila's gross domestic product (GDP). Estimates from a Tobit regression model identified the respondents' knowledge regarding leptospirosis, the susceptibility of their homes to flooding, and the proximity of their homes to sewers as significant factors to consider when developing resource contribution programs for leptospirosis prevention. More efforts need to be made in developing community level preventive programs, and in improving public's knowledge and awareness about leptospirosis. PMID:23644831

  18. Valuing Human Leptospirosis Prevention Using the Opportunity Cost of Labor

    PubMed Central

    Arbiol, Joseph; Borja, Maridel; Yabe, Mitsuyasu; Nomura, Hisako; Gloriani, Nina; Yoshida, Shinichi

    2013-01-01

    Leptospirosis is a serious public health concern in the Philippines, not only because of its increasing incidence rate, but also because of its significant health and economic impacts. Despite its relatively high seroprevalence, knowledge on the economic burden of disease, particularly on the value that the society places on disease prevention remains limited. Obtaining such information is important within the context of public health policy. This study was conducted in Metro Manila to determine the economic burden of leptospirosis, by asking respondents about their willingness to contribute to labor (WTCL) for the prevention of leptospirosis. The respondents pledged an average labor contribution of 10.66 h/month. The average WTCL corresponded to a monetary value of US$4.01 per month when valued using the opportunity cost of labor (leisure rate of time). From the monetized labor contribution, the total economic value of preventing leptospirosis was estimated at US$124.97 million per annum, which represents 1.13% of Metro Manila’s gross domestic product (GDP). Estimates from a Tobit regression model identified the respondents’ knowledge regarding leptospirosis, the susceptibility of their homes to flooding, and the proximity of their homes to sewers as significant factors to consider when developing resource contribution programs for leptospirosis prevention. More efforts need to be made in developing community level preventive programs, and in improving public’s knowledge and awareness about leptospirosis. PMID:23644831

  19. Labor and skills gap analysis of the biomedical research workforce.

    PubMed

    Mason, Julie L; Johnston, Elizabeth; Berndt, Sam; Segal, Katie; Lei, Ming; Wiest, Jonathan S

    2016-08-01

    The United States has experienced an unsustainable increase of the biomedical research workforce over the past 3 decades. This expansion has led to a myriad of consequences, including an imbalance in the number of researchers and available tenure-track faculty positions, extended postdoctoral training periods, increasing age of investigators at first U.S. National Institutes of Health R01 grant, and exodus of talented individuals seeking careers beyond traditional academe. Without accurate data on the biomedical research labor market, challenges will remain in resolving these problems and in advising trainees of viable career options and the skills necessary to be productive in their careers. We analyzed workforce trends, integrating both traditional labor market information and real-time job data. We generated a profile of the current biomedical research workforce, performed labor gap analyses of occupations in the workforce at regional and national levels, and assessed skill transferability between core and complementary occupations. We conclude that although supply into the workforce and the number of job postings for occupations within that workforce have grown over the past decade, supply continues to outstrip demand. Moreover, we identify practical skill sets from real-time job postings to optimally equip trainees for an array of careers to effectively meet future workforce demand.-Mason, J. L., Johnston, E., Berndt, S., Segal, K., Lei, M., Wiest, J. S. Labor and skills gap analysis of the biomedical research workforce. PMID:27075242

  20. Aggregate breakdown of nanoparticulate titania

    NASA Astrophysics Data System (ADS)

    Venugopal, Navin

    Six nanosized titanium dioxide powders synthesized from a sulfate process were investigated. The targeted end-use of this powder was for a de-NOx catalyst honeycomb monolith. Alteration of synthesis parameters had resulted principally in differences in soluble ion level and specific surface area of the powders. The goal of this investigation was to understand the role of synthesis parameters in the aggregation behavior of these powders. Investigation via scanning electron microscopy of the powders revealed three different aggregation iterations at specific length scales. Secondary and higher order aggregate strength was investigated via oscillatory stress rheometry as a means of simulating shear conditions encountered during extrusion. G' and G'' were measured as a function of the applied oscillatory stress. Oscillatory rheometry indicated a strong variation as a function of the sulfate level of the particles in the viscoelastic yield strengths. Powder yield stresses ranged from 3.0 Pa to 24.0 Pa of oscillatory stress. Compaction curves to 750 MPa found strong similarities in extrapolated yield point of stage I and II compaction for each of the powders (at approximately 500 MPa) suggesting that the variation in sulfate was greatest above the primary aggregate level. Scanning electron microscopy of samples at different states of shear in oscillatory rheometry confirmed the variation in the linear elastic region and the viscous flow regime. A technique of this investigation was to approach aggregation via a novel perspective: aggregates are distinguished as being loose open structures that are highly disordered and stochastic in nature. The methodology used was to investigate the shear stresses required to rupture the various aggregation stages encountered and investigate the attempt to realign the now free-flowing constituents comprising the aggregate into a denser configuration. Mercury porosimetry was utilized to measure the pore size of the compact resulting from

  1. Structural changes in the receiving country and future labor migration--the case of Kuwait.

    PubMed

    Shah, N M

    1995-01-01

    This article describes changes in the volume, age and sex composition, retention, productivity, types of occupation, and economic sector of the labor force in Kuwait. The focus is on the structural changes in the indigenous labor force. Data were obtained from censuses and labor force surveys during 1965-93. Policies after the 1990 invasion pertained primarily to security of public employment sector among natives. Over 98% of private sector employment is among non-Kuwaitis. Government programs support high fertility. Female illiteracy has declined, and the proportion of women with a higher education has increased. Natives comprised 20.4% of the total labor force in 1993. About 90% of native males work in the public sector. 45% of total male employment is in the production sector. Around 50% of non-Kuwaiti males have been employed in production work over the decades. Over 90% of Kuwaiti females in 1993 worked in professional or clerical work. Over 50% of total female labor force participation is in the service sector. Concentration in the public sector increased for Kuwaitis and declined for non-Kuwaitis. Labor force participation declined with increasing age. Retirement benefits encouraged early retirement. The private sector is experiencing the departure of long-term migrants and more rapid turnover of labor. Hours of work are longer in the private sector. Kuwait is still dependent on foreign workers in the production and service industries. It is likely that native male workers will replace foreign workers in professional work and administrative/clerical work. Policies that will assure future reliance on imported labor include the assurance of government jobs for Kuwaitis, retirement rules, and the profitability of the trade in labor. PMID:12291221

  2. Child Labor and Health: Quantifying the Global Health Impacts of Child Labor.

    ERIC Educational Resources Information Center

    Graitcer, Philip L.; Lerer, Leonard B.

    Child labor remains one of the most controversial challenges at the end of the 20th century. Approximately 250 million children in developing countries work either full- or part-time. Child labor is not confined to less-developed countries, as economic transitions bring shifts in the prevalence and nature of child labor. Throughout the world,…

  3. 76 FR 67104 - Child Labor Regulations, Orders and Statements of Interpretation; Child Labor Violations-Civil...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-31

    ... Federal Register of September 2, 2011 (76 FR 54836), the Department of Labor published a proposed notice... Interpretation; Child Labor Violations--Civil Money Penalties AGENCY: Wage and Hour Division, Labor. ACTION... money penalty regulations to incorporate into the regulations the processes the Department follows...

  4. An overview of aggregate resources in the United States

    USGS Publications Warehouse

    Langer, William H.; Scott, P.W.; Bristow, C.M.

    2002-01-01

    In 2000 the USA produced about 2.7 billion tonnes of aggregate worth about $13.7 billion. Both crushed stone and sand and gravel are produced in virtually every State, although limited quantities are available in the Gulf Coastal Plain, the Colorado Plateau , the Wyoming Basin and the Great Plains. Prices vary depending on the product and location. Most aggregates are transported by road, and minor amounts by railroad, barge on navigable inland channels, and through the Great Lake ports. Imports and exports of aggregates are very minor. A major amount f crushed stone aggregates is consumed by concrete aggregate. Recycled aggregates account for about 8% of total demand, although the amount recycled is thought to be increasing. Current issues facing the inductry unclude the differences in quality specifications between States, adjusting to the increasing concern for the impact of aggregate mining on the environmentm, health issues from particulate matter and crystalline silica, and the complexity of obtaining permits for extraction. Redcustion in the number od companies extracting aggregrates is likely to occur through acquisitions.

  5. Glycation precedes lens crystallin aggregation

    SciTech Connect

    Swamy, M.S.; Perry, R.E.; Abraham, E.C.

    1987-05-01

    Non-enzymatic glycosylation (glycation) seems to have the potential to alter the structure of crystallins and make them susceptible to thiol oxidation leading to disulfide-linked high molecular weight (HMW) aggregate formation. They used streptozotocin diabetic rats during precataract and cataract stages and long-term cell-free glycation of bovine lens crystallins to study the relationship between glycation and lens crystallin aggregation. HMW aggregates and other protein components of the water-soluble (WS) and urea-soluble (US) fractions were separated by molecular sieve high performance liquid chromatography. Glycation was estimated by both (/sup 3/H)NaBH/sub 4/ reduction and phenylboronate agarose affinity chromatography. Levels of total glycated protein (GP) in the US fractions were about 2-fold higher than in the WS fractions and there was a linear increase in GP in both WS and US fractions. This increase was parallelled by a corresponding increase in HMW aggregates. Total GP extracted by the affinity method from the US fraction showed a predominance of HMW aggregates and vice versa. Cell-free glycation studies with bovine crystallins confirmed the results of the animals studies. Increasing glycation caused a corresponding increase in protein insolubilization and the insoluble fraction thus formed also contained more glycated protein. It appears that lens protein glycation, HMW aggregate formation, and protein insolubilization are interrelated.

  6. Labor in the Public and Nonprofit Sectors.

    ERIC Educational Resources Information Center

    Hamermesh, Daniel S., Ed.

    Originally presented at a Conference on Labor in Nonprofit Industry and Government held at Princeton University, the studies are the first to provide an economic discussion of the public sector labor market. Melvin Reder examines the effect of the absence of the profit motive on employment and wage determination in the public sector. Orley…

  7. 23 CFR 140.906 - Labor costs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Labor costs. 140.906 Section 140.906 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT Reimbursement for Railroad Work § 140.906 Labor costs. (a) General. (1) Salaries and wages, at actual or average rates,...

  8. 23 CFR 140.906 - Labor costs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Labor costs. 140.906 Section 140.906 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT Reimbursement for Railroad Work § 140.906 Labor costs. (a) General. (1) Salaries and wages, at actual or average rates,...

  9. 23 CFR 140.906 - Labor costs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Labor costs. 140.906 Section 140.906 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT Reimbursement for Railroad Work § 140.906 Labor costs. (a) General. (1) Salaries and wages, at actual or average rates,...

  10. Child Labor in Agriculture. ERIC Digest.

    ERIC Educational Resources Information Center

    Davis, Shelley

    An estimated 200,000-800,000 children and adolescents work in the United States as migrant agricultural laborers, either alone or with their families. This digest describes the statutory and economic factors contributing to the presence of children in the fields and the impact of this labor on their health and educational progress. The Fair Labor…

  11. Induction of labor: update and review.

    PubMed

    Bonsack, Carrie F; Lathrop, Anthony; Blackburn, Mary

    2014-01-01

    Rates of labor induction in the United States have more than doubled in the past 2 decades. Trends of indications and risk factors related to induction of labor are also increasing. Professional organizations such as the American College of Obstetricians and Gynecologists and The Joint Commission have taken steps to discourage elective induction of labor prior to 39 weeks' gestation and have created new definitions of early-term, full-term, late-term, and postterm gestation to guide clinicians in the timing of birth for specified indications. Induction of labor is associated with potential risks to both the woman and her fetus. The cost associated with induction of labor and the impact on the health care system is of growing concern. Education of women and the process of shared decision making when obtaining informed consent are key factors in reducing early elective births. Use of tools such as scheduling forms, hard stop methods, induction of labor indication tools, and informed consents may aid the provider in reducing overdiagnosis, overtreatment, and disease creep. This article provides a review of the trends of induction of labor, medical indications and criteria, associated risks, cost and health system impact, and initiatives to lower the incidence of induction of labor.

  12. 24 CFR 1006.345 - Labor standards.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    .... 327). (d) Volunteers. The requirements in 24 CFR part 70 concerning exemptions for the use of... under the Davis-Bacon Act (40 U.S.C. 276a-276a-5) to be paid to laborers and mechanics employed in the... laborers and mechanics employed in the operation, and to architects, technical engineers, draftsmen...

  13. 24 CFR 1006.345 - Labor standards.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    .... 327). (d) Volunteers. The requirements in 24 CFR part 70 concerning exemptions for the use of... under the Davis-Bacon Act (40 U.S.C. 276a-276a-5) to be paid to laborers and mechanics employed in the... laborers and mechanics employed in the operation, and to architects, technical engineers, draftsmen...

  14. 24 CFR 570.603 - Labor standards.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... DEVELOPMENT COMMUNITY FACILITIES COMMUNITY DEVELOPMENT BLOCK GRANTS Other Program Requirements § 570.603 Labor... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Labor standards. 570.603 Section 570.603 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  15. Unfair Labor Practices in the Academic Setting

    ERIC Educational Resources Information Center

    Holway, Loretta W.; O'Donnell, Thomas L. P.

    1974-01-01

    The scope of individual employee rights to engage in activities under the National Labor Relations Act and the concomitant restrictions on employer actions, as interpreted in decisions of the National Labor Relations Board and the courts, are examined on the premise that college administrators are well-advised to understand them. (JT)

  16. Preterm labor: role of the nurse practitioner.

    PubMed

    Doyle, Jennifer; Silber, Angela

    2015-03-12

    The nurse practitioner may play a pivotal role in diagnosing preterm labor through risk assessment and physical exam. While treatment and management of preterm labor are usually beyond the nurse practitioner's scope of practice, they can play an important role in preventing preterm birth through assessment, action, or advocacy.

  17. 24 CFR 1006.345 - Labor standards.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... 327). (d) Volunteers. The requirements in 24 CFR part 70 concerning exemptions for the use of... under the Davis-Bacon Act (40 U.S.C. 276a-276a-5) to be paid to laborers and mechanics employed in the... laborers and mechanics employed in the operation, and to architects, technical engineers, draftsmen...

  18. 75 FR 55251 - Labor Day, 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-09

    ... thirty-fifth. (Presidential Sig.) [FR Doc. 2010-22704 Filed 9-8-10; 11:15 am] Billing code 3195-W0-P ... Proclamation 8555--Labor Day, 2010 #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register / Vol. 75... President ] Proclamation 8555 of September 3, 2010 Labor Day, 2010 By the President of the United States...

  19. 78 FR 54749 - Labor Day, 2013

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-06

    ... United States of America the two hundred and thirty- eighth. (Presidential Sig.) [FR Doc. 2013-21825... Documents#0;#0; ] Proclamation 9012 of August 30, 2013 Labor Day, 2013 By the President of the United States of America A Proclamation On September 5, 1882, in what is thought to be the first Labor Day...

  20. 77 FR 55103 - Labor Day, 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ... two hundred and thirty-seventh. (Presidential Sig.) [FR Doc. 2012-22155 Filed 9-5-12; 11:15 am... Documents#0;#0; ] Proclamation 8857 of August 31, 2012 Labor Day, 2012 By the President of the United States... economic growth. On Labor Day, we celebrate their vital role and reaffirm that America will always...

  1. Ultrasociality and the division of cognitive labor.

    PubMed

    Noles, Nicholaus Samuel; Danovitch, Judith Harmony

    2016-01-01

    Gowdy & Krall describe the development of ultrasociality in terms of economics and the division of labor. We propose that the division of cognitive labor allows humans to behave in an ultrasocial manner without the radical evolutionary changes that are experienced by other species, suggesting that species may traverse different paths to achieve ultrasociality. PMID:27561899

  2. Third Stage of Labor and Acupuncture

    PubMed Central

    Djakovic, Zeljko; Bilić, Nada; Košec, Vesna

    2015-01-01

    Abstract Background: Acupuncture use in obstetrics has been increasing in Western medicine, especially to alleviate complications of pregnancy, the most important cause of maternal mortality worldwide. One quarter of maternal deaths are caused by complications in the third stage of labor, an interval between complete delivery of the baby and the complete expulsion of the placenta. Methods: This review analyzes the increased acupuncture use for pregnancy complications as a potential method of reducting maternal mortality during the third stage of labor. This overview focuses on acupuncture points and techniques to manage the third stage of labor and help patients with retained placentas. Passive (or expectant) management of the third stage of labor is occasionally associated with massive obstetric hemorrhage, a major cause of maternal morbidity and mortality, especially in low-income countries. Conclusions: Active management of the third stage of labor has been shown to reduce the risk of postpartum hemorrhage. Use of acupuncture in the first and second stages of labor could lead to a faster separation of the placenta in the third stage of labor. The possible effects of acupuncture in cases of retained placentas may have significant implications for possible complications and final outcomes of labor. Further studies are needed for more conclusive results. PMID:25784967

  3. Statistical Theories of Discrimination in Labor Markets

    ERIC Educational Resources Information Center

    Aigner, Dennis J.; Cain, Glen G.

    1977-01-01

    Economic discrimination in labor markets, different pay for workers of the same ability, is analyzed in several statistical models using data for black/white and male/female earnings. The conclusion is that statistical theories are unlikely to explain labor market discrimination. (MF)

  4. "Subconscious" Sex Bias and Labor Market Reality.

    ERIC Educational Resources Information Center

    Baldwin, Stephen E.

    1979-01-01

    Discusses the contention that the resentment some men feel toward working women is based on sympathy toward unemployed male breadwinners. Argues that this rationalization ignores the gross discrepancy in the size of the two labor force groups and the real issues in labor market discrimination against women. (Author/IRT)

  5. Immersion in water during labor and delivery.

    PubMed

    2014-04-01

    Immersion in water has been suggested as a beneficial alternative for labor, delivery, or both and over the past decades has gained popularity in many parts of the world. Immersion in water during the first stage of labor may be associated with decreased pain or use of anesthesia and decreased duration of labor. However, there is no evidence that immersion in water during the first stage of labor otherwise improves perinatal outcomes, and it should not prevent or inhibit other elements of care. The safety and efficacy of immersion in water during the second stage of labor have not been established, and immersion in water during the second stage of labor has not been associated with maternal or fetal benefit. Given these facts and case reports of rare but serious adverse effects in the newborn, the practice of immersion in the second stage of labor (underwater delivery) should be considered an experimental procedure that only should be performed within the context of an appropriately designed clinical trial with informed consent. Facilities that plan to offer immersion in the first stage of labor need to establish rigorous protocols for candidate selection, maintenance and cleaning of tubs and immersion pools, infection control procedures, monitoring of mothers and fetuses at appropriate intervals while immersed, and immediately and safely moving women out of the tubs if maternal or fetal concerns develop.

  6. Texas Migrant Labor. 1975 Annual Report.

    ERIC Educational Resources Information Center

    Good Neighbor Commission of Texas, Austin.

    The Good Neighbor Commission of Texas coordinates the work of the Federal, State, and local government toward the improvement of travel and living and working conditions of Texas migrant laborers and their families. Covering the full spectrum of migrant labor activity directly related to the improvement of the well-being of migrant and seasonal…

  7. 24 CFR 266.225 - Labor standards.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... provisions of this section shall not apply to volunteers under the conditions set out in 24 CFR part 70. In... with all labor standards and provisions of 29 CFR parts 1, 3 and 5 that would be applicable to a... established by the Comptroller General, pursuant 29 CFR 5.12, issued by the Secretary of Labor. (2) No...

  8. Wage and Hour Farm Labor Laws.

    ERIC Educational Resources Information Center

    Hertel, Catherine

    This paper, by a teacher of migrants, summarizes various farm labor laws and child labor laws pertaining to migrant and seasonal workers. The Migrant and Seasonal Agricultural Worker Protection Act of 1983 provides workers with assurances about pay, hours, and working conditions, including safety and health. This legislation permits anyone…

  9. Report on the Youth Labor Force. Revised.

    ERIC Educational Resources Information Center

    Bureau of Labor Statistics, Washington, DC.

    This report explains the current U.S. regulations governing child labor; provides a detailed look at youth labor in this country, including how it differs among major demographic groups and economic sectors, and over time; and describes the outcomes of young people's work activities, including occupational injuries and fatalities and other…

  10. Composition Teachers and the Labor Movement.

    ERIC Educational Resources Information Center

    Hendricks, William A.

    Composition teachers should combine self-identification and direct political action by belonging to the labor movement and working collectively toward expanding its range and power and consequently their own. Previously, members of the composition faculty have been involved in the labor movement, but several obstacles may interfere with deeper…

  11. Implications of AFTA on Philippine labor export.

    PubMed

    Villegas, B M

    1993-01-01

    "After summarizing the major features of the ASEAN labor market and patterns of labor migration in Asia, the article describes the origins and current status of the ASEAN Free Trade Area (AFTA) and its main mechanism, the Common Effective Preferential Tariff (CEPT) Scheme." Possible trends in the migration of skilled and professional Philippine workers throughout the Asia-Pacific region are discussed.

  12. Texas Migrant Labor. Annual Report, 1969.

    ERIC Educational Resources Information Center

    Good Neighbor Commission of Texas, Austin.

    Among the responsibilities of the Good Neighbor Commission of Texas are (1) a survey of conditions and (2) a study of problems related to migrant labor in Texas. This annual report of the 1969 migrant scene shows the results of that survey and study. Beginning with an overview of Texas migrant labor, which goes back several years and includes a…

  13. A Short History of American Labor.

    ERIC Educational Resources Information Center

    American Federation of Labor and Congress of Industrial Organizations, Washington, DC.

    This document traces the U.S. labor movement's history, documents its achievements, and describes its goals. The labor movement played a central role in the elevation of the U.S. standard of living through benefits negotiated by unions, such as vacations with pay, pensions, health and welfare protection, and grievance and arbitration procedures.…

  14. 20 CFR 652.9 - Labor disputes.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR ESTABLISHMENT AND FUNCTIONING OF STATE EMPLOYMENT SERVICES Employment Service Operations § 652.9 Labor disputes. (a) State agencies shall make no... agencies shall resume full referral services when they have been notified of, and verified with...

  15. 20 CFR 652.9 - Labor disputes.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR ESTABLISHMENT AND FUNCTIONING OF STATE EMPLOYMENT SERVICES Employment Service Operations § 652.9 Labor disputes. (a) State agencies shall make no... agencies shall resume full referral services when they have been notified of, and verified with...

  16. Internal Labor Markets: An Empirical Investigation.

    ERIC Educational Resources Information Center

    Mahoney, Thomas A.; Milkovich, George T.

    Methods of internal labor market analysis for three organizational areas are presented, along with some evidence about the validity and utility of conceptual descriptions of such markets. The general concept of an internal labor market refers to the process of pricing and allocation of manpower resources with an employing organization and rests…

  17. Childhood Labor in India: Issues and Complexities

    ERIC Educational Resources Information Center

    Viruru, Radhika

    2008-01-01

    It is estimated that more than 12 million children in India under the age of 14 engage in paid labor at least part time, due mostly to economic reasons. Dominant discourses about childhood however conceptualize childhood labor not only as unethical but as exploitation. This article explored the tensions between Western notions of childhood…

  18. Interfacial adsorption and aggregation of amphiphilic proteins

    NASA Astrophysics Data System (ADS)

    Cheung, David

    2012-02-01

    The adsorption and aggregation on liquid interfaces of proteins is important in many biological contexts, such as the formation of aerial structures, immune response, and catalysis. Likewise the adsorption of proteins onto interfaces has applications in food technology, drug delivery, and in personal care products. As such there has been much interest in the study of a wide range of biomolecules at liquid interfaces. One class of proteins that has attracted particular attention are hydrophobins, small, fungal proteins with a distinct, amphiphilic surface structure. This makes these proteins highly surface active and they recently attracted much interest. In order to understand their potential applications a microscopic description of their interfacial and self-assembly is necessary and molecular simulation provides a powerful tool for providing this. In this presentation I will describe some recent work using coarse-grained molecular dynamics simulations to study the interfacial and aggregation behaviour of hydrophobins. Specifically this will present the calculation of their adsorption strength at oil-water and air-water interfaces, investigate the stability of hydrophobin aggregates in solution and their interaction with surfactants.

  19. Cellulose Aggregation under Hydrothermal Pretreatment Conditions.

    PubMed

    Silveira, Rodrigo L; Stoyanov, Stanislav R; Kovalenko, Andriy; Skaf, Munir S

    2016-08-01

    Cellulose, the most abundant biopolymer on Earth, represents a resource for sustainable production of biofuels. Thermochemical treatments make lignocellulosic biomaterials more amenable to depolymerization by exposing cellulose microfibrils to enzymatic or chemical attacks. In such treatments, the solvent plays fundamental roles in biomass modification, but the molecular events underlying these changes are still poorly understood. Here, the 3D-RISM-KH molecular theory of solvation has been employed to analyze the role of water in cellulose aggregation under different thermodynamic conditions. The results show that, under ambient conditions, highly structured hydration shells around cellulose create repulsive forces that protect cellulose microfibrils from aggregating. Under hydrothermal pretreatment conditions, however, the hydration shells lose structure, and cellulose aggregation is favored. These effects are largely due to a decrease in cellulose-water interactions relative to those at ambient conditions, so that cellulose-cellulose attractive interactions become prevalent. Our results provide an explanation to the observed increase in the lateral size of cellulose crystallites when biomass is subject to pretreatments and deepen the current understanding of the mechanisms of biomass modification. PMID:27301535

  20. Silibinin: a novel inhibitor of Aβ aggregation.

    PubMed

    Yin, Fei; Liu, Jianhui; Ji, Xiuhong; Wang, Yanwen; Zidichouski, Jeffrey; Zhang, Junzeng

    2011-02-01

    Alzheimer's disease (AD) is characterized by the abnormal aggregation of amyloid β peptide (Aβ) into extracellular fibrillar deposits known as amyloid plaque. Inhibition of Aβ aggregation is therefore viewed as a potential method to halt or slow the progression of AD. It is reported that silibinin (silybin), a flavonoid derived from the herb milk thistle (Silybum marianum), attenuates cognitive deficits induced by Aβ25-35 peptide and methamphetamine. However, it remains unclear whether silibinin interacts with Aβ peptide directly and decreases Aβ peptide-induced neurotoxicity. In the present study, we identified, through employing a ThT assay and electron microscopic imaging that silibinin also appears to act as a novel inhibitor of Aβ aggregation and this effect showed dose-dependency. We also show that silibinin prevented SH-SY5Y cells from injuries caused by Aβ(1-42)-induced oxidative stress by decreasing H(2)O(2) production in Aβ(1-42)-stressed neurons. Taken together, these results indicate that silibinin may be a novel therapeutic agent for the treatment of AD.

  1. Elective induction of labor: part 2.

    PubMed

    Crosby, Warren

    2008-12-01

    The elective induction of labor has become commonplace, and many are concerned that the practice introduces risks for the woman and the fetus that would not be incurred if labor had been allowed to begin spontaneously. This second paper of a two-part communication reviews the risks and benefits of the elective induction of labor, and concludes that the risks of the induction of labor are few when the patient is properly screened medically and appropriately informed. The principal worry is a doubled risk of Cesarean delivery among primigravidas (not multiparas) in whom labor is electively induced. The benefits of selecting the date of delivery are powerful incentives for busy working women. But the benefits are primarily social, and add to the convenience of both the patient and her doctor. The risks, however, are medical, and are not confined to the pregnancy at risk. Appropriately informed consent is the key to balance the risks and benefits.

  2. Microbial community dynamics in soil aggregates shape biogeochemical gas fluxes from soil profiles - upscaling an aggregate biophysical model.

    PubMed

    Ebrahimi, Ali; Or, Dani

    2016-09-01

    Microbial communities inhabiting soil aggregates dynamically adjust their activity and composition in response to variations in hydration and other external conditions. These rapid dynamics shape signatures of biogeochemical activity and gas fluxes emitted from soil profiles. Recent mechanistic models of microbial processes in unsaturated aggregate-like pore networks revealed a highly dynamic interplay between oxic and anoxic microsites jointly shaped by hydration conditions and by aerobic and anaerobic microbial community abundance and self-organization. The spatial extent of anoxic niches (hotspots) flicker in time (hot moments) and support substantial anaerobic microbial activity even in aerated soil profiles. We employed an individual-based model for microbial community life in soil aggregate assemblies represented by 3D angular pore networks. Model aggregates of different sizes were subjected to variable water, carbon and oxygen contents that varied with soil depth as boundary conditions. The study integrates microbial activity within aggregates of different sizes and soil depth to obtain estimates of biogeochemical fluxes from the soil profile. The results quantify impacts of dynamic shifts in microbial community composition on CO2 and N2 O production rates in soil profiles in good agreement with experimental data. Aggregate size distribution and the shape of resource profiles in a soil determine how hydration dynamics shape denitrification and carbon utilization rates. Results from the mechanistic model for microbial activity in aggregates of different sizes were used to derive parameters for analytical representation of soil biogeochemical processes across large scales of practical interest for hydrological and climate models. PMID:27152862

  3. Mechanism of Algal Aggregation by Bacillus sp. Strain RP1137

    PubMed Central

    Powell, Ryan J.

    2014-01-01

    Alga-derived biofuels are one of the best alternatives for economically replacing liquid fossil fuels with a fungible renewable energy source. Production of fuel from algae is technically feasible but not yet economically viable. Harvest of dilute algal biomass from the surrounding water remains one of the largest barriers to economic production of algal biofuel. We identified Bacillus sp. strain RP1137 in a previous study and showed that this strain can rapidly aggregate several biofuel-producing algae in a pH- and divalent-cation-dependent manner. In this study, we further characterized the mechanism of algal aggregation by RP1137. We show that aggregation of both algae and bacteria is optimal in the exponential phase of growth and that the density of ionizable residues on the RP1137 cell surface changes with growth stage. Aggregation likely occurs via charge neutralization with calcium ions at the cell surface of both algae and bacteria. We show that charge neutralization occurs at least in part through binding of calcium to negatively charged teichoic acid residues. The addition of calcium also renders both algae and bacteria more able to bind to hydrophobic beads, suggesting that aggregation may occur through hydrophobic interactions. Knowledge of the aggregation mechanism may enable engineering of RP1137 to obtain more efficient algal harvesting. PMID:24771029

  4. Crystal aggregation in kidney stones; a polymer aggregation problem?

    NASA Astrophysics Data System (ADS)

    Wesson, J.; Beshensky, A.; Viswanathan, P.; Zachowicz, W.; Kleinman, J.

    2008-03-01

    Kidney stones most frequently form as aggregates of calcium oxalate monohydrate (COM) crystals with organic layers between them, and the organic layers contain principally proteins. The pathway leading to the formation of these crystal aggregates in affected people has not been identified, but stone forming patients are thought to have a defect in the structure or distribution of urinary proteins, which normally protect against stone formation. We have developed two polyelectrolyte models that will induce COM crystal aggregation in vitro, and both are consistent with possible urinary protein compositions. The first model was based on mixing polyanionic and polycationic proteins, in portions such that the combined protein charge is near zero. The second model was based on reducing the charge density on partially charged polyanionic proteins, specifically Tamm-Horsfall protein, the second most abundant protein in urine. Both models demonstrated polymer phase separation at solution conditions where COM crystal aggregation was observed. Correlation with data from other bulk crystallization measurements suggest that the anionic side chains form critical binding interactions with COM surfaces that are necessary along with the phase separation process to induce COM crystal aggregation.

  5. Lubrication properties of protein aggregate dispersions in a soft contact.

    PubMed

    Chojnicka, Agnieszka; de Jong, Saskia; de Kruif, Cornelus G; Visschers, Ronald W

    2008-02-27

    The lubrication, rheological, and molecular properties of two different protein aggregate dispersions were compared: globular aggregates of whey protein isolate (WPI) and fibrillar aggregates of ovalbumin from egg white. These dispersions are models for the lubricating fluid that is present between the tongue and the palate when consuming liquid or gelled products. To simulate oral conditions, a commercial tribometer was modified so that soft rubber surfaces could be used. This allowed us to measure friction at low contact pressures similar to those present between the tongue and palate. Clear correlations were observed between the measured friction coefficients and specific properties of the lubricating fluid such as protein concentration and aggregate size and shape. Furthermore, surface properties like elasticity, surface-surface interactions, and surface roughness had a significant effect on the friction under conditions that are relevant for texture perception. We conclude that in vitro measurements at low contact pressure provide valuable information for understanding and controlling food properties that modulate oral friction.

  6. Ceramic roadway aggregates with improved polish and wear resistance

    NASA Astrophysics Data System (ADS)

    Petty, A. V., Jr.

    1981-08-01

    Synthetic ceramic aggregates having high wear- and polish-resistance were developed. Three hundred aggregate compositions, incorporating a variety of low-cost 'waste' materials were evaluated. Aggregates were produced using conventional ceramic processing techniques and fired at temperatures ranging from 900-1,500 C. British Wheel and L. A. Abrasion tests were used for initial screening of the aggregates. These data, raw material costs, availability, and energy requirements, were used to select nine compositions for circular track tests. Economic evaluations showed that present production costs, based on a 1,000 ton-per-day operation ranged from $10 to $120 per ton of material produced. Guyana bauxite was used as a standard.

  7. Questions and Answers on Unfair Labor Practices. A Practitioner's Guide.

    ERIC Educational Resources Information Center

    Indiana Univ., Bloomington. Midwest Center for Public Sector Labor Relations.

    An unfair labor practice is the violation of any right granted employees, unions, or employers by a collective bargaining law. This guide answers common questions about unfair labor practices in public sector labor relations. The booklet is divided into two sections, unfair employer labor practices and unfair union labor practices. The section…

  8. 7 CFR 3560.577 - Tenant priorities for labor housing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... disabled domestic farm laborer households who were active in the local farm labor market area at the time... disabled domestic farm laborer households who were not active in the local farm labor market at the time of... 7 Agriculture 15 2011-01-01 2011-01-01 false Tenant priorities for labor housing. 3560.577...

  9. 7 CFR 3560.577 - Tenant priorities for labor housing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... disabled domestic farm laborer households who were active in the local farm labor market area at the time... disabled domestic farm laborer households who were not active in the local farm labor market at the time of... 7 Agriculture 15 2010-01-01 2010-01-01 false Tenant priorities for labor housing. 3560.577...

  10. 29 CFR 780.331 - Crew leaders and labor contractors.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Crew leaders and labor contractors. 780.331 Section 780.331 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS EXEMPTIONS APPLICABLE TO AGRICULTURE, PROCESSING OF...

  11. 29 CFR 780.331 - Crew leaders and labor contractors.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Crew leaders and labor contractors. 780.331 Section 780.331 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS EXEMPTIONS APPLICABLE TO AGRICULTURE, PROCESSING OF...

  12. 29 CFR 552.108 - Child labor provisions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Child labor provisions. 552.108 Section 552.108 Labor... OF THE FAIR LABOR STANDARDS ACT TO DOMESTIC SERVICE Interpretations § 552.108 Child labor provisions. Congress made no change in section 12 as regards domestic service employees. Accordingly, the child...

  13. 29 CFR 552.108 - Child labor provisions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Child labor provisions. 552.108 Section 552.108 Labor... OF THE FAIR LABOR STANDARDS ACT TO DOMESTIC SERVICE Interpretations § 552.108 Child labor provisions. Congress made no change in section 12 as regards domestic service employees. Accordingly, the child...

  14. 29 CFR 552.108 - Child labor provisions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Child labor provisions. 552.108 Section 552.108 Labor... OF THE FAIR LABOR STANDARDS ACT TO DOMESTIC SERVICE Interpretations § 552.108 Child labor provisions. Congress made no change in section 12 as regards domestic service employees. Accordingly, the child...

  15. 29 CFR 552.108 - Child labor provisions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Child labor provisions. 552.108 Section 552.108 Labor... OF THE FAIR LABOR STANDARDS ACT TO DOMESTIC SERVICE Interpretations § 552.108 Child labor provisions. Congress made no change in section 12 as regards domestic service employees. Accordingly, the child...

  16. 29 CFR 552.108 - Child labor provisions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Child labor provisions. 552.108 Section 552.108 Labor... OF THE FAIR LABOR STANDARDS ACT TO DOMESTIC SERVICE Interpretations § 552.108 Child labor provisions. Congress made no change in section 12 as regards domestic service employees. Accordingly, the child...

  17. 29 CFR 780.315 - Local hand harvest laborers.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Agriculture That Is Exempted From the Minimum Wage and Overtime Pay Requirements Under Section 13(a)(6... 29 Labor 3 2013-07-01 2013-07-01 false Local hand harvest laborers. 780.315 Section 780.315 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF...

  18. 29 CFR 780.332 - Exchange of labor between farmers.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Employment in Agriculture That Is Exempted From the Minimum Wage and Overtime Pay Requirements Under Section... 29 Labor 3 2014-07-01 2014-07-01 false Exchange of labor between farmers. 780.332 Section 780.332 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR...

  19. 29 CFR 780.315 - Local hand harvest laborers.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Agriculture That Is Exempted From the Minimum Wage and Overtime Pay Requirements Under Section 13(a)(6... 29 Labor 3 2012-07-01 2012-07-01 false Local hand harvest laborers. 780.315 Section 780.315 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF...

  20. 29 CFR 780.332 - Exchange of labor between farmers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Employment in Agriculture That Is Exempted From the Minimum Wage and Overtime Pay Requirements Under Section... 29 Labor 3 2011-07-01 2011-07-01 false Exchange of labor between farmers. 780.332 Section 780.332 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR...