19 CFR 132.17 - Export certificate for sugar-containing products subject to tariff-rate quota.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 1 2011-04-01 2011-04-01 false Export certificate for sugar-containing products subject to tariff-rate quota. 132.17 Section 132.17 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... certificate for sugar-containing products subject to tariff-rate quota. (a) Requirement. For sugar-containing...

27 CFR 6.71 - Quota sales.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Quota sales. 6.71 Section 6.71 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS âTIED-HOUSEâ Unlawful Inducements Quota Sales § 6.71 Quota sales. The act by an industry member of requiring a retailer to take...

27 CFR 6.71 - Quota sales.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Quota sales. 6.71 Section 6.71 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS âTIED-HOUSEâ Unlawful Inducements Quota Sales § 6.71 Quota sales. The act by an industry member of requiring a retailer to take...

Sustainable aggregates production : green applications for aggregate by-products.

DOT National Transportation Integrated Search

2015-06-01

Increased emphasis in the construction industry on sustainability and recycling requires production of : aggregate gradations with lower dust (cleaner aggregates) and smaller maximum sizeshence, increased : amount of quarry by-products (QBs). QBs ...

21 CFR 1315.30 - Procurement and import quotas.

Code of Federal Regulations, 2014 CFR

2014-04-01

... PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas... adequate and uninterrupted supply of, ephedrine, pseudoephedrine, and phenylpropanolamine the Administrator...

21 CFR 1315.30 - Procurement and import quotas.

Code of Federal Regulations, 2011 CFR

2011-04-01

... PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas... adequate and uninterrupted supply of, ephedrine, pseudoephedrine, and phenylpropanolamine the Administrator...

21 CFR 1315.30 - Procurement and import quotas.

Code of Federal Regulations, 2010 CFR

2010-04-01

... PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas... adequate and uninterrupted supply of, ephedrine, pseudoephedrine, and phenylpropanolamine the Administrator...

21 CFR 1315.30 - Procurement and import quotas.

Code of Federal Regulations, 2012 CFR

2012-04-01

... PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas... adequate and uninterrupted supply of, ephedrine, pseudoephedrine, and phenylpropanolamine the Administrator...

21 CFR 1315.30 - Procurement and import quotas.

Code of Federal Regulations, 2013 CFR

2013-04-01

... PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas... adequate and uninterrupted supply of, ephedrine, pseudoephedrine, and phenylpropanolamine the Administrator...

75 FR 47258 - Determination of Total Amounts of Fiscal Year 2011 Tariff-Rate Quotas for Raw Cane Sugar and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-05

... Determination of Total Amounts of Fiscal Year 2011 Tariff-Rate Quotas for Raw Cane Sugar and Certain Sugars...) 2011 in-quota aggregate quantity of the raw, as well as, refined and specialty sugar Tariff-Rate Quotas (TRQ) as required under the U.S. World Trade Organization (WTO) commitments. The FY 2011 raw cane sugar...

77 FR 55451 - Determination of Total Amounts of Fiscal Year 2013 Tariff-Rate Quotas for Raw Cane Sugar and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-10

... Secretary Determination of Total Amounts of Fiscal Year 2013 Tariff-Rate Quotas for Raw Cane Sugar and...) 2013 (October 1, 2012-September 30, 2013) in-quota aggregate quantity of the raw, as well as, refined and specialty sugar Tariff-Rate Quotas (TRQ). The FY 2013 raw cane sugar TRQ is established at 1,117...

21 CFR 1303.11 - Aggregate production quotas.

Code of Federal Regulations, 2010 CFR

2010-04-01

... are manufactured from it, the economic and physical availability of raw materials for use in manufacturing and for inventory purposes, yield and stability problems, potential disruptions to production...

7 CFR 1463.105 - Base quota levels for eligible quota holders.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Base quota levels for eligible quota holders. 1463.105 Section 1463.105 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY... TRANSITION PROGRAM Tobacco Transition Payment Program § 1463.105 Base quota levels for eligible quota holders...

7 CFR 1463.105 - Base quota levels for eligible quota holders.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 10 2012-01-01 2012-01-01 false Base quota levels for eligible quota holders. 1463.105 Section 1463.105 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY... TRANSITION PROGRAM Tobacco Transition Payment Program § 1463.105 Base quota levels for eligible quota holders...

Effect of production quotas on economic and environmental values of growth rate and feed efficiency in sea cage fish farming.

PubMed

Besson, M; de Boer, I J M; Vandeputte, M; van Arendonk, J A M; Quillet, E; Komen, H; Aubin, J

2017-01-01

In sea cage fish farming, production quotas aim to constrain the impact of fish farming on the surrounding ecosystem. It is unknown how these quotas affect economic profitability and environmental impact of genetic improvement. We combined bioeconomic modelling with life cycle assessment (LCA) to calculate the economic (EV) and environmental (ENV) values of thermal growth coefficient (TGC) and feed conversion ratio (FCR) of sea bass reared in sea cages, given four types of quota commonly used in Europe: annual production (Qprod), annual feed distributed (Qannual_feed), standing stock (Qstock), and daily feed distributed (Qdaily_feed). ENV were calculated for LCA impact categories climate change, eutrophication and acidification. ENV were expressed per ton of fish produced per year (ENV(fish)) and per farm per year (ENV(farm)). Results show that irrespective of quota used, EV of FCR as well as ENV(fish) and ENV(farm) were always positive, meaning that improving FCR increased profit and decreased environmental impacts. However, the EV and the ENV(fish) of TGC were positive only when quota was Qstock or Qdaily_feed. Moreover, the ENV(farm) of TGC was negative in Qstock and Qdaily_feed quotas, meaning that improving TGC increased the environmental impact of the farm. We conclude that Qstock quota and Qdaily_feed quota are economically favorable to a genetic improvement of TGC, a major trait for farmers. However, improving TGC increases the environmental impact of the farm. Improving FCR represents a good opportunity to balance out this increase but more information on its genetic background is needed to develop breeding programs improving FCR.

21 CFR 1315.23 - Procedure for fixing individual manufacturing quotas.

Code of Federal Regulations, 2014 CFR

2014-04-01

... IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Individual... manufacturing quotas for ephedrine, pseudoephedrine, and phenylpropanolamine, the Administrator shall allocate...

21 CFR 1315.23 - Procedure for fixing individual manufacturing quotas.

Code of Federal Regulations, 2013 CFR

2013-04-01

... IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Individual... manufacturing quotas for ephedrine, pseudoephedrine, and phenylpropanolamine, the Administrator shall allocate...

21 CFR 1315.23 - Procedure for fixing individual manufacturing quotas.

Code of Federal Regulations, 2012 CFR

2012-04-01

... IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Individual... manufacturing quotas for ephedrine, pseudoephedrine, and phenylpropanolamine, the Administrator shall allocate...

21 CFR 1315.23 - Procedure for fixing individual manufacturing quotas.

Code of Federal Regulations, 2011 CFR

2011-04-01

... IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Individual... manufacturing quotas for ephedrine, pseudoephedrine, and phenylpropanolamine, the Administrator shall allocate...

21 CFR 1315.32 - Obtaining a procurement quota.

Code of Federal Regulations, 2013 CFR

2013-04-01

... PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas..., pseudoephedrine, or phenylpropanolamine, or whose requirement of registration is waived pursuant to § 1309.24 of this chapter, and who desires to use during the next calendar year any ephedrine, pseudoephedrine, or...

21 CFR 1315.32 - Obtaining a procurement quota.

Code of Federal Regulations, 2011 CFR

2011-04-01

... PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas..., pseudoephedrine, or phenylpropanolamine, or whose requirement of registration is waived pursuant to § 1309.24 of this chapter, and who desires to use during the next calendar year any ephedrine, pseudoephedrine, or...

21 CFR 1315.32 - Obtaining a procurement quota.

Code of Federal Regulations, 2014 CFR

2014-04-01

... PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas..., pseudoephedrine, or phenylpropanolamine, or whose requirement of registration is waived pursuant to § 1309.24 of this chapter, and who desires to use during the next calendar year any ephedrine, pseudoephedrine, or...

21 CFR 1315.32 - Obtaining a procurement quota.

Code of Federal Regulations, 2012 CFR

2012-04-01

... PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas..., pseudoephedrine, or phenylpropanolamine, or whose requirement of registration is waived pursuant to § 1309.24 of this chapter, and who desires to use during the next calendar year any ephedrine, pseudoephedrine, or...

21 CFR 1315.32 - Obtaining a procurement quota.

Code of Federal Regulations, 2010 CFR

2010-04-01

... PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas..., pseudoephedrine, or phenylpropanolamine, or whose requirement of registration is waived pursuant to § 1309.24 of this chapter, and who desires to use during the next calendar year any ephedrine, pseudoephedrine, or...

21 CFR 1315.36 - Amending an import quota.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Amending an import quota. 1315.36 Section 1315.36 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND PRODUCTION QUOTAS... necessary to provide for medical, scientific, or other legitimate purposes regarding the chemical. The...

21 CFR 1315.34 - Obtaining an import quota.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Obtaining an import quota. 1315.34 Section 1315.34 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND PRODUCTION QUOTAS... imports, the estimated medical, scientific, and industrial needs of the United States, the establishment...

7 CFR 1463.105 - Base quota levels for eligible quota holders.

Code of Federal Regulations, 2013 CFR

2013-01-01

... the BQL adjustment factor 1.071295. (Note: The factor adjusts the 2004 basic quota to the 2002 basic... farm. (Note: In the case of undivided tract ownership, BQL must be distributed among the tract quota... basic quota, multiplied by the BQL adjustment factor 1.23457. (Note: The factor adjusts the 2004 basic...

7 CFR 1463.105 - Base quota levels for eligible quota holders.

Code of Federal Regulations, 2014 CFR

2014-01-01

... the BQL adjustment factor 1.071295. (Note: The factor adjusts the 2004 basic quota to the 2002 basic... farm. (Note: In the case of undivided tract ownership, BQL must be distributed among the tract quota... basic quota, multiplied by the BQL adjustment factor 1.23457. (Note: The factor adjusts the 2004 basic...

21 CFR 1315.25 - Increase in individual manufacturing quotas.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Increase in individual manufacturing quotas. 1315.25 Section 1315.25 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Individual Manufacturing...

21 CFR 1315.25 - Increase in individual manufacturing quotas.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Increase in individual manufacturing quotas. 1315.25 Section 1315.25 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Individual Manufacturing...

21 CFR 1315.25 - Increase in individual manufacturing quotas.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Increase in individual manufacturing quotas. 1315.25 Section 1315.25 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Individual Manufacturing...

21 CFR 1315.26 - Reduction in individual manufacturing quotas.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Reduction in individual manufacturing quotas. 1315.26 Section 1315.26 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Individual Manufacturing...

21 CFR 1315.25 - Increase in individual manufacturing quotas.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Increase in individual manufacturing quotas. 1315.25 Section 1315.25 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Individual Manufacturing...

21 CFR 1315.26 - Reduction in individual manufacturing quotas.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Reduction in individual manufacturing quotas. 1315.26 Section 1315.26 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Individual Manufacturing...

21 CFR 1315.26 - Reduction in individual manufacturing quotas.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Reduction in individual manufacturing quotas. 1315.26 Section 1315.26 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Individual Manufacturing...

21 CFR 1315.26 - Reduction in individual manufacturing quotas.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Reduction in individual manufacturing quotas. 1315.26 Section 1315.26 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Individual Manufacturing...

21 CFR 1315.25 - Increase in individual manufacturing quotas.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Increase in individual manufacturing quotas. 1315.25 Section 1315.25 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Individual Manufacturing...

21 CFR 1315.26 - Reduction in individual manufacturing quotas.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Reduction in individual manufacturing quotas. 1315.26 Section 1315.26 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Individual Manufacturing...

78 FR 56646 - Determination of Total Amounts of Fiscal Year 2014 WTO Tariff-Rate Quotas for Raw Cane Sugar and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-13

... Secretary Determination of Total Amounts of Fiscal Year 2014 WTO Tariff- Rate Quotas for Raw Cane Sugar and... the Fiscal Year (FY) 2014 (October 1, 2013-September 30, 2014) in-quota aggregate quantity of raw cane sugar at 1,117,195 metric tons raw value (MTRV). The Secretary also announces the establishment of the...

50 CFR 622.42 - Quotas.

Code of Federal Regulations, 2012 CFR

2012-10-01

.... Except for the quotas for Gulf and South Atlantic coral, the quotas include species harvested from state... person subject to the bag limits.) (a) Gulf reef fish—(1) Commercial quotas. The following quotas apply to persons who fish under commercial vessel permits for Gulf reef fish, as required under § 622.4(a...

50 CFR 622.42 - Quotas.

Code of Federal Regulations, 2011 CFR

2011-10-01

.... Except for the quotas for Gulf and South Atlantic coral, the quotas include species harvested from state... person subject to the bag limits.) (a) Gulf reef fish—(1) Commercial quotas. The following quotas apply to persons who fish under commercial vessel permits for Gulf reef fish, as required under § 622.4(a...

50 CFR 622.42 - Quotas.

Code of Federal Regulations, 2010 CFR

2010-10-01

... South Atlantic coral, the quotas include species harvested from state waters adjoining the EEZ. Quotas... limits.) (a) Gulf reef fish—(1) Commercial quotas. The following quotas apply to persons who fish under commercial vessel permits for Gulf reef fish, as required under § 622.4(a)(2)(v). (i) Red snapper -3.542...

Follow-up study of the regional quota system of Japanese medical schools and prefecture scholarship programmes: a study protocol.

PubMed

Matsumoto, Masatoshi; Takeuchi, Keisuke; Tanaka, Junko; Tazuma, Susumu; Inoue, Kazuo; Owaki, Tetsuhiro; Iguchi, Seitaro; Maeda, Takahiro

2016-04-15

Given the shortage of physicians, particularly in rural areas, the Japanese government has rapidly expanded the number of medical school students by adding chiikiwaku (regional quotas) since 2008. Quota entrants now account for 17% of all medical school entrants. Quota entrants are usually local high school graduates who receive a scholarship from the prefecture government. In exchange, they temporarily practise in that prefecture, including its rural areas, after graduation. Many prefectures also have scholarship programmes for non-quota students in exchange for postgraduate in-prefecture practice. The objective of this cohort study, conducted by the Japanese Council for Community-based Medical Education, is to evaluate the outcomes of the quota admission system and prefecture scholarship programmes nationwide. There are 3 groups of study participants: quota without scholarship, quota with scholarship and non-quota with scholarship. Under the support of government ministries and the Association of Japan Medical Colleges, and participation of all prefectures and medical schools, passing rate of the National Physician License Examination, scholarship buy-out rate, geographic distribution and specialties distribution of each group are analysed. Participants who voluntarily participated are followed by linking their baseline information to data in the government's biennial Physician Census. Results to date have shown that, despite medical schools' concerns about academic quality, the passing rate of the National Physician License Examination in each group was higher than that of all medical school graduates. The Ethics Committee for Epidemiological Research of Hiroshima University and the Research Ethics Committee of Nagasaki University Graduate School of Biomedical Sciences permitted this study. No individually identifiable results will be presented in conferences or published in journals. The aggregated results will be reported to concerned government ministries

7 CFR 1463.105 - Base quota levels for eligible quota holders.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Base quota levels for eligible quota holders. 1463.105 Section 1463.105 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS 2005-2014 TOBACCO...

50 CFR 622.39 - Quotas.

Code of Federal Regulations, 2014 CFR

2014-10-01

...) Commercial quota for red snapper—5.610 million lb (2.545 million kg), round weight. (ii) Deep-water groupers... million lb (0.464 million kg). (iii) Shallow-water groupers (SWG) have separate quotas for gag and red grouper and a combined quota for other shallow-water grouper (Other SWG) species (including black grouper...

21 CFR 1315.36 - Amending an import quota.

Code of Federal Regulations, 2011 CFR

2011-04-01

... FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas § 1315.36... quantity of ephedrine, pseudoephedrine, or phenylpropanolamine and distribute the chemical or drug products...

21 CFR 1315.36 - Amending an import quota.

Code of Federal Regulations, 2013 CFR

2013-04-01

... FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas § 1315.36... quantity of ephedrine, pseudoephedrine, or phenylpropanolamine and distribute the chemical or drug products...

21 CFR 1315.36 - Amending an import quota.

Code of Federal Regulations, 2014 CFR

2014-04-01

... FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas § 1315.36... quantity of ephedrine, pseudoephedrine, or phenylpropanolamine and distribute the chemical or drug products...

21 CFR 1315.36 - Amending an import quota.

Code of Federal Regulations, 2012 CFR

2012-04-01

... FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas § 1315.36... quantity of ephedrine, pseudoephedrine, or phenylpropanolamine and distribute the chemical or drug products...

50 CFR 665.269 - Quotas.

Code of Federal Regulations, 2013 CFR

2013-10-01

...) General. The quotas limiting the amount of precious coral that may be taken in any precious coral permit area during the fishing year are listed in § 665.269(d). Only live coral is counted toward the quota... bed will be closed to all nonselective coral harvesting after the quota for one species of coral has...

50 CFR 665.467 - Quotas.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Quotas. (a) General. The quotas limiting the amount of precious coral that may be taken in any precious coral permit area during the fishing year are listed in § 665.467(d). Only live coral is counted toward... conditional bed will be closed to all nonselective coral harvesting after the quota for one species of coral...

50 CFR 665.667 - Quotas.

Code of Federal Regulations, 2014 CFR

2014-10-01

... § 665.667 Quotas. (a) General. The quotas limiting the amount of precious coral that may be taken in any precious coral permit area during the fishing year are listed in § 665.667(d). Only live coral is counted.... A conditional bed will be closed to all nonselective coral harvesting after the quota for one...

50 CFR 665.467 - Quotas.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Quotas. (a) General. The quotas limiting the amount of precious coral that may be taken in any precious coral permit area during the fishing year are listed in § 665.467(d). Only live coral is counted toward... conditional bed will be closed to all nonselective coral harvesting after the quota for one species of coral...

50 CFR 665.269 - Quotas.

Code of Federal Regulations, 2012 CFR

2012-10-01

...) General. The quotas limiting the amount of precious coral that may be taken in any precious coral permit area during the fishing year are listed in § 665.269(d). Only live coral is counted toward the quota... bed will be closed to all nonselective coral harvesting after the quota for one species of coral has...

50 CFR 665.467 - Quotas.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Quotas. (a) General. The quotas limiting the amount of precious coral that may be taken in any precious coral permit area during the fishing year are listed in § 665.467(d). Only live coral is counted toward... conditional bed will be closed to all nonselective coral harvesting after the quota for one species of coral...

50 CFR 665.467 - Quotas.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Quotas. (a) General. The quotas limiting the amount of precious coral that may be taken in any precious coral permit area during the fishing year are listed in § 665.467(d). Only live coral is counted toward... conditional bed will be closed to all nonselective coral harvesting after the quota for one species of coral...

50 CFR 665.667 - Quotas.

Code of Federal Regulations, 2013 CFR

2013-10-01

... § 665.667 Quotas. (a) General. The quotas limiting the amount of precious coral that may be taken in any precious coral permit area during the fishing year are listed in § 665.667(d). Only live coral is counted.... A conditional bed will be closed to all nonselective coral harvesting after the quota for one...

50 CFR 665.667 - Quotas.

Code of Federal Regulations, 2012 CFR

2012-10-01

... § 665.667 Quotas. (a) General. The quotas limiting the amount of precious coral that may be taken in any precious coral permit area during the fishing year are listed in § 665.667(d). Only live coral is counted.... A conditional bed will be closed to all nonselective coral harvesting after the quota for one...

50 CFR 665.269 - Quotas.

Code of Federal Regulations, 2014 CFR

2014-10-01

...) General. The quotas limiting the amount of precious coral that may be taken in any precious coral permit area during the fishing year are listed in § 665.269(d). Only live coral is counted toward the quota... bed will be closed to all nonselective coral harvesting after the quota for one species of coral has...

50 CFR 665.467 - Quotas.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Quotas. (a) General. The quotas limiting the amount of precious coral that may be taken in any precious coral permit area during the fishing year are listed in § 665.467(d). Only live coral is counted toward... conditional bed will be closed to all nonselective coral harvesting after the quota for one species of coral...

50 CFR 622.384 - Quotas.

Code of Federal Regulations, 2013 CFR

2013-10-01

... and western zones separated by 87°31.1′ W. long., which is a line directly south from the Alabama... years, the hook-and-line quota is 551,448 lb (250,133 kg) and the run-around gillnet quota is 551,448 lb (250,133 kg). (2) Northern. For the 2012 to 2013 fishing year, the quota is 197,064 lb (89,387 kg). For...

50 CFR 622.384 - Quotas.

Code of Federal Regulations, 2014 CFR

2014-10-01

... and western zones separated by 87°31.1′ W. long., which is a line directly south from the Alabama... years, the hook-and-line quota is 551,448 lb (250,133 kg) and the run-around gillnet quota is 551,448 lb (250,133 kg). (2) Northern. For the 2012 to 2013 fishing year, the quota is 197,064 lb (89,387 kg). For...

19 CFR 132.22 - When quota is filled.

Code of Federal Regulations, 2011 CFR

2011-04-01

... TREASURY QUOTAS Mail Importation of Absolute Quota Merchandise § 132.22 When quota is filled. Any packages containing merchandise subject to an absolute quota which is filled shall be returned to the postmaster for...

19 CFR 132.22 - When quota is filled.

Code of Federal Regulations, 2010 CFR

2010-04-01

... TREASURY QUOTAS Mail Importation of Absolute Quota Merchandise § 132.22 When quota is filled. Any packages containing merchandise subject to an absolute quota which is filled shall be returned to the postmaster for...

50 CFR 622.39 - Quotas.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., DEPARTMENT OF COMMERCE FISHERIES OF THE CARIBBEAN, GULF OF MEXICO, AND SOUTH ATLANTIC Reef Fish Resources of the Gulf of Mexico § 622.39 Quotas. See § 622.8 for general provisions regarding quota applicability...

50 CFR 665.667 - Quotas.

Code of Federal Regulations, 2011 CFR

2011-10-01

... species of coral has been taken. (c) Reserves and reserve release. The quotas for exploratory area, X-P-PI... permit area, X-P-PI, has an annual quota of 1,000 kg for all precious coral MUS combined with the...

50 CFR 665.667 - Quotas.

Code of Federal Regulations, 2010 CFR

2010-10-01

... species of coral has been taken. (c) Reserves and reserve release. The quotas for exploratory area, X-P-PI... permit area, X-P-PI, has an annual quota of 1,000 kg for all precious coral MUS combined with the...

[Work quota setting and man-hour productivity estimation in pathologists].

PubMed

Svistunov, V V; Makarov, S V; Makarova, A E

The paper considers the development and current state of the regulation of work quota setting and remuneration in pathologists. Reasoning from the current staff standards for morbid anatomy departments (units), the authors present a method to calculate the load of pathologists. The essence of the proposed method is demonstrated using a specific example.

19 CFR 132.13 - Quotas after opening.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Customs custody until Headquarters has determined the quantity entitled to the quota rate. (ii) Absolute. Except as provided for in § 142.21 (e)(2) and (g) of this chapter, absolute quota merchandise shall not... merchandise shall not be released until Customs has determined the quantity entitled to absolute quota status...

19 CFR 132.13 - Quotas after opening.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Customs custody until Headquarters has determined the quantity entitled to the quota rate. (ii) Absolute. Except as provided for in § 142.21 (e)(2) and (g) of this chapter, absolute quota merchandise shall not... merchandise shall not be released until Customs has determined the quantity entitled to absolute quota status...

21 CFR 1303.21 - Individual manufacturing quotas.

Code of Federal Regulations, 2010 CFR

2010-04-01

... controlled substance listed in Schedule I or II, and who applies for a manufacturing quota, an individual... basic class. Any manufacturing quota fixed and issued by the Administrator shall be subject to his... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Individual manufacturing quotas. 1303.21 Section...

Dutch dairy farms after milk quota abolition: Economic and environmental consequences of a new manure policy.

PubMed

Klootwijk, C W; Van Middelaar, C E; Berentsen, P B M; de Boer, I J M

2016-10-01

The abolition of the Dutch milk quota system has been accompanied by the introduction of a new manure policy to limit phosphate production (i.e., excretion via manure) on expanding dairy farms. The objective of this study was to evaluate the effect of these recent policy changes on the farm structure, management, labor income, nitrogen and phosphate surpluses, and greenhouse gas emissions of an average Dutch dairy farm. The new manure policy requires that any increase in phosphate production be partly processed and partly applied to additional farmland. In addition, phosphate quotas have been introduced. Herein, we used a whole-farm optimization model to simulate an average farm before and after quota abolition and introduction of the new manure policy. The objective function of the model maximized labor income. We combined the model with a farm nutrient balance and life-cycle assessment to determine environmental impact. Based on current prices, increasing the number of cows after quota abolition was profitable until manure processing or additional land was required to comply with the new manure policy. Manure processing involved treatment so that phosphate was removed from the national manure market. Farm intensity in terms of milk per hectare increased by about 4%, from 13,578kg before quota abolition to 14,130kg after quota abolition. Labor income increased by €505/yr. When costs of manure processing decreased from €13 to €8/t of manure or land costs decreased from €1,187 to €573/ha, farm intensity could increase up to 20% until the phosphate quota became limiting. Farms that had already increased their barn capacity to prepare for expansion after milk quota abolition could benefit from purchasing extra phosphate quota to use their full barn capacity. If milk prices increased from €355 to €420/t, farms could grow unlimited, provided that the availability of external inputs such as labor, land, barn capacity, feed, and phosphate quota at current

21 CFR 1315.22 - Procedure for applying for individual manufacturing quotas.

Code of Federal Regulations, 2014 CFR

2014-04-01

... JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE... person who is registered to manufacture ephedrine, pseudoephedrine, or phenylpropanolamine and who...

21 CFR 1315.22 - Procedure for applying for individual manufacturing quotas.

Code of Federal Regulations, 2013 CFR

2013-04-01

... JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE... person who is registered to manufacture ephedrine, pseudoephedrine, or phenylpropanolamine and who...

21 CFR 1315.22 - Procedure for applying for individual manufacturing quotas.

Code of Federal Regulations, 2011 CFR

2011-04-01

... JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE... person who is registered to manufacture ephedrine, pseudoephedrine, or phenylpropanolamine and who...

21 CFR 1315.22 - Procedure for applying for individual manufacturing quotas.

Code of Federal Regulations, 2012 CFR

2012-04-01

... JUSTICE IMPORTATION AND PRODUCTION QUOTAS FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE... person who is registered to manufacture ephedrine, pseudoephedrine, or phenylpropanolamine and who...

21 CFR 1303.26 - Reduction in individual manufacturing quotas.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Individual Manufacturing Quotas § 1303.26 Reduction in individual manufacturing quotas. The Administrator may at any time reduce an individual manufacturing quota for a basic class of controlled substance listed... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Reduction in individual manufacturing quotas. 1303...

50 CFR 648.294 - Individual fishing quota (IFQ) program.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 50 Wildlife and Fisheries 12 2013-10-01 2013-10-01 false Individual fishing quota (IFQ) program... Management Measures for the Tilefish Fishery § 648.294 Individual fishing quota (IFQ) program. (a) IFQ... quota share holders who held IFQ quota share as of September 1 of a given fishing year. Allocations...

50 CFR 648.294 - Individual fishing quota (IFQ) program.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 50 Wildlife and Fisheries 12 2014-10-01 2014-10-01 false Individual fishing quota (IFQ) program... Management Measures for the Tilefish Fishery § 648.294 Individual fishing quota (IFQ) program. (a) IFQ... quota share holders who held IFQ quota share as of September 1 of a given fishing year. Allocations...

50 CFR 665.167 - Quotas.

Code of Federal Regulations, 2014 CFR

2014-10-01

.... (a) General. The quotas limiting the amount of precious coral that may be taken in any precious coral permit area during the fishing year are listed in § 665.167(d). Only live coral is counted toward the... conditional bed will be closed to all nonselective coral harvesting after the quota for one species of coral...

50 CFR 665.167 - Quotas.

Code of Federal Regulations, 2012 CFR

2012-10-01

.... (a) General. The quotas limiting the amount of precious coral that may be taken in any precious coral permit area during the fishing year are listed in § 665.167(d). Only live coral is counted toward the... conditional bed will be closed to all nonselective coral harvesting after the quota for one species of coral...

50 CFR 665.167 - Quotas.

Code of Federal Regulations, 2011 CFR

2011-10-01

.... (a) General. The quotas limiting the amount of precious coral that may be taken in any precious coral permit area during the fishing year are listed in § 665.167(d). Only live coral is counted toward the... conditional bed will be closed to all nonselective coral harvesting after the quota for one species of coral...

50 CFR 665.167 - Quotas.

Code of Federal Regulations, 2010 CFR

2010-10-01

.... (a) General. The quotas limiting the amount of precious coral that may be taken in any precious coral permit area during the fishing year are listed in § 665.167(d). Only live coral is counted toward the... conditional bed will be closed to all nonselective coral harvesting after the quota for one species of coral...

50 CFR 665.167 - Quotas.

Code of Federal Regulations, 2013 CFR

2013-10-01

.... (a) General. The quotas limiting the amount of precious coral that may be taken in any precious coral permit area during the fishing year are listed in § 665.167(d). Only live coral is counted toward the... conditional bed will be closed to all nonselective coral harvesting after the quota for one species of coral...

Biological parameters used in setting captive-breeding quotas for Indonesia's breeding facilities.

PubMed

Janssen, Jordi; Chng, Serene C L

2018-02-01

The commercial captive breeding of wildlife is often seen as a potential conservation tool to relieve pressure on wild populations, but laundering of wild-sourced specimens as captive bred can seriously undermine conservation efforts and provide a false sense of sustainability. Indonesia is at the center of such controversy; therefore, we examined Indonesia's captive-breeding production plan (CBPP) for 2016. We compared the biological parameters used in the CBPP with parameters in the literature and with parameters suggested by experts on each species and identified shortcomings of the CBPP. Production quotas for 99 out of 129 species were based on inaccurate or unrealistic biological parameters and production quotas deviated more than 10% from what parameters in the literature allow for. For 38 species, the quota exceeded the number of animals that can be bred based on the biological parameters (range 100-540%) calculated with equations in the CBPP. We calculated a lower reproductive output for 88 species based on published biological parameters compared with the parameters used in the CBPP. The equations used in the production plan did not appear to account for other factors (e.g., different survival rate for juveniles compared to adult animals) involved in breeding the proposed large numbers of specimens. We recommend the CBPP be adjusted so that realistic published biological parameters are applied and captive-breeding quotas are not allocated to species if their captive breeding is unlikely to be successful or no breeding stock is available. The shortcomings in the current CBPP create loopholes that mean mammals, reptiles, and amphibians from Indonesia declared captive bred may have been sourced from the wild. © 2017 Society for Conservation Biology.

19 CFR 10.23 - Standards, quotas, and visas.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 1 2013-04-01 2013-04-01 false Standards, quotas, and visas. 10.23 Section 10.23... Abroad with United States Components § 10.23 Standards, quotas, and visas. All requirements and... properties, quotas, and visas, apply to assembled articles eligible for the exemption in the same manner as...

19 CFR 10.23 - Standards, quotas, and visas.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 1 2010-04-01 2010-04-01 false Standards, quotas, and visas. 10.23 Section 10.23... Abroad with United States Components § 10.23 Standards, quotas, and visas. All requirements and... properties, quotas, and visas, apply to assembled articles eligible for the exemption in the same manner as...

19 CFR 10.23 - Standards, quotas, and visas.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 1 2012-04-01 2012-04-01 false Standards, quotas, and visas. 10.23 Section 10.23... Abroad with United States Components § 10.23 Standards, quotas, and visas. All requirements and... properties, quotas, and visas, apply to assembled articles eligible for the exemption in the same manner as...

19 CFR 10.23 - Standards, quotas, and visas.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 1 2011-04-01 2011-04-01 false Standards, quotas, and visas. 10.23 Section 10.23... Abroad with United States Components § 10.23 Standards, quotas, and visas. All requirements and... properties, quotas, and visas, apply to assembled articles eligible for the exemption in the same manner as...

19 CFR 10.23 - Standards, quotas, and visas.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 1 2014-04-01 2014-04-01 false Standards, quotas, and visas. 10.23 Section 10.23... Abroad with United States Components § 10.23 Standards, quotas, and visas. All requirements and... properties, quotas, and visas, apply to assembled articles eligible for the exemption in the same manner as...

75 FR 56137 - Controlled Substances: Proposed Aggregate Production Quotas for 2011

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-15

...,500,000 Amphetamine (for sale) 18,600,000 Cocaine 247,000 Codeine (for conversion) 65,000,000 Codeine... Business Regulatory Enforcement Fairness Act of 1996. This action will not result in an annual effect on... effects on competition, employment, investment, productivity, innovation, or on the ability of United...

76 FR 65537 - Controlled Substances: Proposed Aggregate Production Quotas for 2012

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-21

..., expressed in grams of anhydrous acid or base, be established as follows: Proposed 2012 Basic class--Schedule... Methadone Intermediate 26,000,000 Methamphetamine 3,130,000 [750,000 grams of levo-desoxyephedrine for use in a non-controlled, non- prescription product; 2,331,000 grams for methamphetamine mostly for...

U.S. Clothing and Textile Trade with China and the World: Trends Since the End of Quotas

DTIC Science & Technology

2007-07-10

the road to quota-free trade for clothing and textiles, the MFA expanded the scope of the LTA to include wool and man-made fibers. However, concerns...starting a 10-year process of eliminating quotas for international trade in clothing and textiles. The ATC’s quota phase-out contained two concurrent...goods. The ATC also required that products from different categories — textiles and clothing, wool , cotton or man-made fibres, etc. — be included in

Protein Aggregation and Its Impact on Product Quality

PubMed Central

Roberts, Christopher J.

2014-01-01

Protein pharmaceutical products are typically active as folded monomers that are composed of one or more protein chains, such as the heavy and light chains in monoclonal antibodies that are a mainstay of current drug pipelines. There are numerous possible aggregated states for a given protein, some of which are potentially useful, while most of which are considered deleterious from the perspective of pharmaceutical product quality and performance. This review provides an overview of how and why different aggregated states of proteins occur, how this potentially impacts product quality and performance, fundamental approaches to control aggregate formation, and the practical approaches that are currently used in the pharmaceutical industry. PMID:25173826

A look at construction aggregates production

USGS Publications Warehouse

Willett, Jason Christopher

2009-01-01

Construction aggregates are defined as the combination of crushed stone and construction sand and gravel. Aggregates are one of the most accessible natural resources on Earth and one of the fundamental building blocks of our society. They have been used from the earliest times of our civilization for a variety of applications that have increased in number and complexity with time and technological progress. Despite the relatively low but increasing unit value of its basic products, the construction aggregates industry is a major contributor to and an indicator of the economic well-being of the nation.

75 FR 10223 - Whaling Provisions; Aboriginal Subsistence Whaling Quotas

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-05

... whales. SUMMARY: NMFS provides notification of the aboriginal subsistence whaling quota for bowhead whales that it has assigned to the Alaska Eskimo Whaling Commission (AEWC), and other limitations...). For 2010, the quota is 75 bowhead whales struck. This quota and other limitations govern the harvest...

76 FR 16388 - Whaling Provisions; Aboriginal Subsistence Whaling Quotas

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-23

... whales. SUMMARY: NMFS provides notification of the aboriginal subsistence whaling quota for bowhead whales that it has assigned to the Alaska Eskimo Whaling Commission (AEWC), and other limitations...). For 2011, the quota is 75 bowhead whales struck. This quota and other limitations govern the harvest...

50 CFR 622.8 - Quotas-general.

Code of Federal Regulations, 2014 CFR

2014-10-01

... applicable ACL or ACT is reached or projected to be reached). (c) Reopening. When a sector has been closed based on a projection of the quota specified in this part, or the ACL specified in the applicable annual... subsequent data indicate that the quota or ACL was not reached, the Assistant Administrator may file a...

50 CFR 622.8 - Quotas-general.

Code of Federal Regulations, 2013 CFR

2013-10-01

... applicable ACL or ACT is reached or projected to be reached). (c) Reopening. When a sector has been closed based on a projection of the quota specified in this part, or the ACL specified in the applicable annual... subsequent data indicate that the quota or ACL was not reached, the Assistant Administrator may file a...

Quota sampling in internet research: practical issues.

PubMed

Im, Eun-Ok; Chee, Wonshik

2011-07-01

Quota sampling has been suggested as a potentially good method for Internet-based research and has been used by several researchers working with Internet samples. However, very little is known about the issues or concerns in using a quota sampling method in Internet research. The purpose of this article was to present the practical issues using quota sampling in an Internet-based study. During the Internet study, the research team recorded all recruitment issues that arose and made written notes indicating the possible reasons for the problems. In addition, biweekly team discussions were conducted for which written records were kept. Overall, quota sampling was effective in ensuring that an adequate number of midlife women were recruited from the targeted ethnic groups. However, during the study process, we encountered the following practical issues using quota sampling: (1) difficulty reaching out to women in lower socioeconomic classes, (2) difficulty ensuring authenticity of participants' identities, (3) participants giving inconsistent answers for the screening questions versus the Internet survey questions, (4) potential problems with a question on socioeconomic status, (5) resentment toward the research project and/or researchers because of rejection, and (6) a longer time and more expense than anticipated.

21 CFR 1303.12 - Procurement quotas.

Code of Federal Regulations, 2011 CFR

2011-04-01

... purposes of manufacturing, shall apply on DEA Form 250 for a procurement quota for such basic class. A... specified unit of the second basic class. DEA Form 250 shall be filed on or before April 1 of the year preceding the calendar year for which the procurement quota is being applied. Copies of DEA Form 250 may be...

77 FR 21540 - Whaling Provisions; Aboriginal Subsistence Whaling Quotas

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-10

... whales. SUMMARY: NMFS notifies the public of the aboriginal subsistence whaling quota for bowhead whales... Commission (IWC). For 2012, the quota is 75 bowhead whales struck. This quota and other applicable limitations govern the harvest of bowhead whales by members of the AEWC. DATES: Effective April 10, 2012...

75 FR 53013 - Fiscal Year 2011 Tariff-rate Quota Allocations for Raw Cane Sugar, Refined and Specialty Sugar...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-30

... for Raw Cane Sugar, Refined and Specialty Sugar, and Sugar-containing Products; Revision AGENCY... August 17, 2010 concerning Fiscal Year 2011 tariff-rate quota allocations of raw cane sugar, refined and... announced that sugar entering the United States under the Fiscal Year 2011 raw sugar tariff-rate quota will...

76 FR 50285 - Fiscal Year 2012 Tariff-Rate Quota Allocations for Raw Cane Sugar, Refined and Specialty Sugar...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-12

... for Raw Cane Sugar, Refined and Specialty Sugar and Sugar-Containing Products AGENCY: Office of the... quantity of the tariff-rate quotas for imported raw cane sugar, refined and specialty sugar and sugar...), the United States maintains tariff-rate quotas (TRQs) for imports of raw cane sugar and refined sugar...

78 FR 57445 - Fiscal Year 2014 WTO Tariff-Rate Quota Allocations for Raw Cane Sugar, Refined and Specialty...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-18

... Allocations for Raw Cane Sugar, Refined and Specialty Sugar, and Sugar-Containing Products AGENCY: Office of..., 2013, through Sept. 30, 2014) in-quota quantity of the tariff-rate quotas (TRQs) for imported raw cane...), the United States maintains TRQs for imports of raw cane sugar and refined sugar (syrups and molasses...

7 CFR 718.204 - Reconstitution of allotments, quotas, and bases.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 7 2011-01-01 2011-01-01 false Reconstitution of allotments, quotas, and bases. 718... PROVISIONS APPLICABLE TO MULTIPLE PROGRAMS Reconstitution of Farms, Allotments, Quotas, and Bases § 718.204 Reconstitution of allotments, quotas, and bases. (a) Farms shall be reconstituted in accordance with this subpart...

7 CFR 718.204 - Reconstitution of allotments, quotas, and bases.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 7 2010-01-01 2010-01-01 false Reconstitution of allotments, quotas, and bases. 718... PROVISIONS APPLICABLE TO MULTIPLE PROGRAMS Reconstitution of Farms, Allotments, Quotas, and Bases § 718.204 Reconstitution of allotments, quotas, and bases. (a) Farms shall be reconstituted in accordance with this subpart...

19 CFR 132.5 - Merchandise imported in excess of quota quantities.

Code of Federal Regulations, 2011 CFR

2011-04-01

... quantities. (a) Absolute quota merchandise. Absolute quota merchandise imported in excess of the quantity... merchandise. Merchandise imported in excess of either an absolute or a tariff-rate quota may be held for the...

19 CFR 132.5 - Merchandise imported in excess of quota quantities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... quantities. (a) Absolute quota merchandise. Absolute quota merchandise imported in excess of the quantity... merchandise. Merchandise imported in excess of either an absolute or a tariff-rate quota may be held for the...

21 CFR 1315.34 - Obtaining an import quota.

Code of Federal Regulations, 2013 CFR

2013-04-01

... FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas § 1315.34 Obtaining an import quota. (a) Any person who is registered to import ephedrine, pseudoephedrine, or... desires to import during the next calendar year any ephedrine, pseudoephedrine, or phenylpropanolamine or...

21 CFR 1315.34 - Obtaining an import quota.

Code of Federal Regulations, 2011 CFR

2011-04-01

... FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas § 1315.34 Obtaining an import quota. (a) Any person who is registered to import ephedrine, pseudoephedrine, or... desires to import during the next calendar year any ephedrine, pseudoephedrine, or phenylpropanolamine or...

21 CFR 1315.34 - Obtaining an import quota.

Code of Federal Regulations, 2014 CFR

2014-04-01

... FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas § 1315.34 Obtaining an import quota. (a) Any person who is registered to import ephedrine, pseudoephedrine, or... desires to import during the next calendar year any ephedrine, pseudoephedrine, or phenylpropanolamine or...

21 CFR 1315.34 - Obtaining an import quota.

Code of Federal Regulations, 2012 CFR

2012-04-01

... FOR EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Procurement and Import Quotas § 1315.34 Obtaining an import quota. (a) Any person who is registered to import ephedrine, pseudoephedrine, or... desires to import during the next calendar year any ephedrine, pseudoephedrine, or phenylpropanolamine or...

21 CFR 1315.27 - Abandonment of quota.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Abandonment of quota. 1315.27 Section 1315.27 Food... may at any time abandon his right to manufacture all or any part of the quota by filing with the Drug... to manufacture. The Administrator may, in his discretion, allocate the amount among the other...

21 CFR 1315.27 - Abandonment of quota.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Abandonment of quota. 1315.27 Section 1315.27 Food... may at any time abandon his right to manufacture all or any part of the quota by filing with the Drug... to manufacture. The Administrator may, in his discretion, allocate the amount among the other...

21 CFR 1315.27 - Abandonment of quota.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Abandonment of quota. 1315.27 Section 1315.27 Food... may at any time abandon his right to manufacture all or any part of the quota by filing with the Drug... to manufacture. The Administrator may, in his discretion, allocate the amount among the other...

21 CFR 1315.27 - Abandonment of quota.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Abandonment of quota. 1315.27 Section 1315.27 Food... may at any time abandon his right to manufacture all or any part of the quota by filing with the Drug... to manufacture. The Administrator may, in his discretion, allocate the amount among the other...

21 CFR 1315.27 - Abandonment of quota.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Abandonment of quota. 1315.27 Section 1315.27 Food... may at any time abandon his right to manufacture all or any part of the quota by filing with the Drug... to manufacture. The Administrator may, in his discretion, allocate the amount among the other...

75 FR 55828 - Controlled Substances: Final Revised Aggregate Production Quotas for 2010

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-14

...) 18,600,000 g Carfentanil 200 g Cocaine 247,000 g Codeine (for conversion) 65,000,000 g Codeine (for... effect on the economy of $100,000,000 or more; a major increase in costs or prices; or significant adverse effects on competition, employment, investment, productivity, innovation, or on the ability of...

Production of lightweight aggregates from washing aggregate sludge and fly ash

NASA Astrophysics Data System (ADS)

González-Corrochano, Beatriz; Alonso-Azcárate, Jacinto; Rodas, Magdalena

2010-05-01

Increasing generation of wastes is one of the main environmental problems in industrialised countries. Heat treatment at high temperatures can convert some types of wastes into ceramic products with a wide range of microstructural features and properties (Bethanis et al., 2004). A lightweight aggregate (LWA) is a granular material with a bulk density (bd) not exceeding 1.20 g/cm3 or with a particle density not exceeding 2.00 g/cm3 (UNE-EN-13055-1, 2003). They have become a focus of interest because the low particle density and the low bulk density entail a decrease in the load transmitted to the ground, and less work and effort are required to transport them (De' Gennaro et al., 2004). The benefits associated with these low densities, which are due to the formation of voids and pores, are very good thermal and acoustic insulation and materials with a good resistance to fire (Benbow, 1987; Fakhfakh et al., 2007). The objective was to recycle fly ash, used motor oil from cars and mineral wastes from washing aggregate sludge, in order to obtain a usable material such as lightweight aggregates, and also to ensure that they are of good quality for different applications. Raw materials have been physically, chemically and mineralogically characterized. On the basis of the results obtained, they were mixed, milled to a grain size of less than 200 μm (Yasuda, 1991), formed into pellets, pre-heated for 5 min and sintered in a rotary kiln at 1150°C, 1175°C, 1200°C and 1225°C for 10 and 15 min at each temperature (Theating). Effects of raw material characteristics, heating temperature and dwell time on the following LWAs properties were determined: loss on ignition (LOI), bloating index (BI), loose bulk density (bd), apparent and dry particle density (ad, dd), voids (H), water absorption (WA24h) and compressive strength (S). The products obtained were lightweight aggregates in accordance with norm UNE-EN-13055-1 (bd ≤1.20 g/cm3 or particle density ≤2.00 g/cm3). LWAs

Environmental aspects and renewable energy sources in the production of construction aggregate

NASA Astrophysics Data System (ADS)

Skrzypczak, Izabela; Kokoszka, Wanda; Buda-Ożóg, Lidia; Kogut, Janusz; Słowik, Marta

2017-11-01

The main activity of open pit mining of aggregates are aggregates' exploitation of natural mineral deposits and its modification in order to obtain high-quality aggregates. The development of aggregate production is conditioned by a number of factors. The most important are: documented material resources, mining and manufacturing capabilities, the need of environmental protection (environmental aspects), the subordination of the plan of spatial development, formal and legal issues, as well as economic and financial aspects. While identifying and assessing the environmental impacts of manufacturing aggregates one may distinguish those environmental aspects that have or may have the greatest magnitude of the impact on the environment as a result of industrial activities. Manufacturers producing aggregates located in the areas covered by the special environmental protection require extra diligence in the conduct of mining activities for preservation of natural resources. The article discusses some main environmental aspects of the production of construction aggregates on the example of one of the largest producers of this material in Subcarpathian province of Poland. Environmental protection in production of aggregates may refer to four aspects: the use of natural resources, having excluded land from agriculture and forestry, land reclamation after exploitation, and use of energy from renewable energy sources. The economic and environmental impact of production volume of aggregates is evaluated by the index information capacity method and the method of graphs.

Across species-pool aggregation alters grassland productivity and diversity.

PubMed

McKenna, Thomas P; Yurkonis, Kathryn A

2016-08-01

Plant performance is determined by the balance of intra- and interspecific neighbors within an individual's zone of influence. If individuals interact over smaller scales than the scales at which communities are measured, then altering neighborhood interactions may fundamentally affect community responses. These interactions can be altered by changing the number (species richness), abundances (species evenness), and positions (species pattern) of the resident plant species, and we aimed to test whether aggregating species at planting would alter effects of species richness and evenness on biomass production at a common scale of observation in grasslands. We varied plant species richness (2, 4, or 8 species and monocultures), evenness (0.64, 0.8, or 1.0), and pattern (planted randomly or aggregated in groups of four individuals) within 1 × 1 m plots established with transplants from a pool of 16 tallgrass prairie species and assessed plot-scale biomass production and diversity over the first three growing seasons. As expected, more species-rich plots produced more biomass by the end of the third growing season, an effect associated with a shift from selection to complementarity effects over time. Aggregating conspecifics at a 0.25-m scale marginally reduced biomass production across all treatments and increased diversity in the most even plots, but did not alter biodiversity effects or richness-productivity relationships. Results support the hypothesis that fine-scale species aggregation affects diversity by promoting species coexistence in this system. However, results indicate that inherent changes in species neighborhood relationships along grassland diversity gradients may only minimally affect community (meter) - scale responses among similarly designed biodiversity-ecosystem function studies. Given that species varied in their responses to local aggregation, it may be possible to use such species-specific results to spatially design larger-scale grassland

78 FR 13028 - Whaling Provisions; Aboriginal Subsistence Whaling Quotas

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-26

... whales. SUMMARY: NMFS notifies the public of the aboriginal subsistence whaling quota for bowhead whales... is 75 bowhead whales struck. This quota and other applicable limitations govern the harvest of bowhead whales by members of the AEWC. DATES: Effective February 26, 2013. ADDRESSES: Office of...

Flexible modulation of risk attitude during decision-making under quota.

PubMed

Fujimoto, Atsushi; Takahashi, Hidehiko

2016-10-01

Risk attitude is often regarded as an intrinsic parameter in the individual personality. However, ethological studies reported state-dependent strategy optimization irrespective of individual preference. To synthesize the two contrasting literatures, we developed a novel gambling task that dynamically manipulated the quota severity (required outcome to clear the task) in a course of choice trials and conducted a task-fMRI study in human participants. The participants showed their individual risk preference when they had no quota constraint ('individual-preference mode'), while they adopted state-dependent optimal strategy when they needed to achieve a quota ('strategy-optimization mode'). fMRI analyses illustrated that the interplay among prefrontal areas and salience-network areas reflected the quota severity and the utilization of the optimal strategy, shedding light on the neural substrates of the quota-dependent risk attitude. Our results demonstrated the complex nature of risk-sensitive decision-making and may provide a new perspective for the understanding of problematic risky behaviors in human. Copyright © 2016 Elsevier Inc. All rights reserved.

How important are dual economy effects for aggregate productivity?

PubMed Central

Vollrath, Dietrich

2013-01-01

This paper brings together development accounting techniques and the dual economy model to address the role that factor markets have in creating variation in aggregate total factor productivity (TFP). Development accounting research has shown that much of the variation in income across countries can be attributed to differences in TFP. The dual economy model suggests that aggregate productivity is depressed by having too many factors allocated to low productivity work in agriculture. Data show large differences in marginal products of similar factors within many developing countries, offering prima facie evidence of this misallocation. Using a simple two-sector decomposition of the economy, this article estimates the role of these misallocations in accounting for the cross-country income distribution. A key contribution is the ability to bring sector-specific data on human and physical capital stocks to the analysis. Variation across countries in the degree of misallocation is shown to account for 30–40% of the variation in income per capita, and up to 80% of the variation in aggregate TFP. PMID:23946553

Ceramic ware waste as coarse aggregate for structural concrete production.

PubMed

García-González, Julia; Rodríguez-Robles, Desirée; Juan-Valdés, Andrés; Morán-Del Pozo, Julia M; Guerra-Romero, M Ignacio

2015-01-01

The manufacture of any kind of product inevitably entails the production of waste. The quantity of waste generated by the ceramic industry, a very important sector in Spain, is between 5% and 8% of the final output and it is therefore necessary to find an effective waste recovery method. The aim of the study reported in the present article was to seek a sustainable means of managing waste from the ceramic industry through the incorporation of this type of waste in the total replacement of conventional aggregate (gravel) used in structural concrete. Having verified that the recycled ceramic aggregates met all the technical requirements imposed by current Spanish legislation, established in the Code on Structural Concrete (EHE-08), then it is prepared a control concrete mix and the recycled concrete mix using 100% recycled ceramic aggregate instead of coarse natural aggregate. The concretes obtained were subjected to the appropriate tests in order to conduct a comparison of their mechanical properties. The results show that the concretes made using ceramic sanitary ware aggregate possessed the same mechanical properties as those made with conventional aggregate. It is therefore possible to conclude that the reuse of recycled ceramic aggregate to produce recycled concrete is a feasible alternative for the sustainable management of this waste.

50 CFR 648.140 - Catch quotas and other restrictions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... specification process, provided that new information does not require a modification to the multiple-year quotas, to determine the allowable levels of fishing and other restrictions necessary to result in a target... target exploitation rate specified in paragraph (a) of this section is not exceeded: (1) Research quota...

50 CFR 648.294 - Individual fishing quota (IFQ) program.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 50 Wildlife and Fisheries 12 2012-10-01 2012-10-01 false Individual fishing quota (IFQ) program... Management Measures for the Tilefish Fishery § 648.294 Individual fishing quota (IFQ) program. (a) IFQ... allocation permit holders who held an IFQ permit as of September 1 of a giving fishing year. Allocations...

Energy consumption quota management of Wanda commercial buildings in China

NASA Astrophysics Data System (ADS)

Sun, D. B.; Xiao, H.; Wang, X.; Liu, J. J.; Wang, X.; Jin, X. Q.; Wang, J.; Xie, X. K.

2016-08-01

There is limited research of commercial buildings’ energy use data conducted based on practical analysis in China nowadays. Some energy consumption quota tools like Energy Star in U.S or VDI 3807 in Germany have limitation in China's building sector. This study introduces an innovative methodology of applying energy use quota model and empirical management to commercial buildings, which was in accordance of more than one hundred opened shopping centers of a real estate group in China. On the basis of statistical benchmarking, a new concept of “Modified coefficient”, which considers weather, occupancy, business layout, operation schedule and HVAC efficiency, is originally introduced in this paper. Our study shows that the average energy use quota increases from north to south. The average energy use quota of sample buildings is 159 kWh/(m2.a) of severe cold climate zone, 179 kWh/(m2.a) of cold zone, 188 kWh/(m2.a) of hot summer and cold winter zone, and 200 kWh/(m2.a) of hot summer and warm winter zone. The energy use quota model has been validated in the property management for year 2016, providing a new method of commercial building energy management to the industry. As a key result, there is 180 million energy saving potential based on energy quota management in 2016, equals to 6.2% saving rate of actual energy use in 2015.

Valorization of lignite combustion residues and ferroalumina in the production of aggregates.

PubMed

Anagnostopoulos, I M; Stivanakis, V E; Angelopoulos, G N; Papamantellos, D C

2010-02-15

The present research study investigates the synergy of industrial solid by-products from lignite combustion (fly ash and bottom ash) and aluminum production (ferroalumina) in the production of lightweight aggregates (LWA). The process consists of two stages, pelletization and sintering. Bottom ash (BA) is used as the principal raw material in mixtures while ferroalumina (FAL) is added in lower percentages (5-30 wt%). BA carbon content is used as the fuel of sintering process in high temperatures, around 1250 degrees C, and gas generation is responsible for porous structure formation. Physical properties such as porosity, water absorption and bulk density, of sintering products are measured. Increase of FAL percentage in sintering mixtures results in decrease of porosity from 61% to 35% and of water absorption from 61% to 21% and in increase of bulk density from 1.02 g/cm(3) to 1.80 g/cm(3) of the produced aggregates. Aggregates produced by FAL addition up to 20 wt% are characterized as LWA. Aggregates formed are used in the production of concrete specimens. Compressive strength of concrete increases by increasing FAL addition in aggregates from 5 wt% to 15 wt% (highest strength value), while decrease by increasing FAL addition from 20 wt% to 30 wt%. FAL addition in lignite ashes sintering mixtures (up to 15 wt%) is considered as an important parameter for enhancing aggregates strength.

Gender quotas for women in national politics: A comparative analysis across development thresholds.

PubMed

Rosen, Jennifer

2017-08-01

Women's share of global lower or single house parliamentary seats has increased by over 70% over the course of the 21st century. Yet these increases have not been uniform across countries. Rather countries with low levels of socioeconomic development have outpaced developed democracies in terms of the gains made in the formal political representation of women. One reasonable explanation for this trend is the adoption in many poorer countries of national gender quota legislation, that is, affirmative action laws intended to compensate for sex discrimination in the electoral process. Yet, cross-national analyses examining quotas as an explanatory factor typically use a simple binary (yes/no) variable that either conflates the diverse intra-quota variations into a single variable or includes only one part of the many quota variations. By contrast, using an originally compiled dataset that includes 167 countries from 1992 to 2012, this paper employs measures of gender quota legislation that capture the complexity and considerable diversity of existing quota legislation. These measures allow us to identify the specific factors that have helped so many less developed countries rise to the top of international rankings in recent years. The findings indicate that the effect of each type of gender quota, as well as other explanatory variables, do not operate in the same way across all countries. Specifically, voluntary political party quotas are substantially more effective in developed countries, while reserved seat quotas are only significant in least developed countries. Electoral candidate quotas, on the other hand, can be significant across all countries, however only have a positive effect when they are accompanied by placement mandates that ensure women are placed in winnable positions, sanctions for non-compliance that are significant enough to force adherence, and a minimum mandated threshold of at least 30%. Copyright © 2017 Elsevier Inc. All rights reserved.

50 CFR 679.41 - Transfer of quota shares and IFQ.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Section 679.41 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND... ALASKA Individual Fishing Quota Management Measures § 679.41 Transfer of quota shares and IFQ. (a... from the QS holder's immediate family to receive survivorship transfer privileges in the event of the...

Research on the optimization of quota design in real estate

NASA Astrophysics Data System (ADS)

Sun, Chunling; Ma, Susu; Zhong, Weichao

2017-11-01

Quota design is one of the effective methods of cost control in real estate development project and widely used in the current real estate development project to control the engineering construction cost, but quota design have many deficiencies in design process. For this purpose, this paper put forward a method to achieve investment control of real estate development project, which combine quota design and value engineering(VE) at the stage of design. Specifically, it’s an optimizing for the structure of quota design. At first, determine the design limits by investment estimate value, then using VE to carry on initial allocation of design limits and gain the functional target cost, finally, consider the whole life cycle cost (LCC) and operational problem in practical application to finish complex correction for the functional target cost. The improved process can control the project cost more effectively. It not only can control investment in a certain range, but also make the project realize maximum value within investment.

Quotas, Relocation and Jobs

ERIC Educational Resources Information Center

Blumrosen, Alfred

1975-01-01

This testimony, before a public hearing of the New York City Commission on Human Rights in May 1974, has two express focuses: one is the question of quotas, and the other is the problem of relocation of plants and facilities in the suburban areas and the consequent difficulties minorities face in retaining equal employment opportunities.…

Soil Aggregate Stability and Grassland Productivity Associations in a Northern Mixed-Grass Prairie

PubMed Central

Reinhart, Kurt O.; Vermeire, Lance T.

2016-01-01

Soil aggregate stability data are often predicted to be positively associated with measures of plant productivity, rangeland health, and ecosystem functioning. Here we revisit the hypothesis that soil aggregate stability is positively associated with plant productivity. We measured local (plot-to-plot) variation in grassland community composition, plant (aboveground) biomass, root biomass, % water-stable soil aggregates, and topography. After accounting for spatial autocorrelation, we observed a negative association between % water-stable soil aggregates (0.25–1 and 1–2 mm size classes of macroaggregates) and dominant graminoid biomass, and negative associations between the % water-stable aggregates and the root biomass of a dominant sedge (Carex filifolia). However, variation in total root biomass (0–10 or 0–30 cm depths) was either negatively or not appreciably associated with soil aggregate stabilities. Overall, regression slope coefficients were consistently negative thereby indicating the general absence of a positive association between measures of plant productivity and soil aggregate stability for the study area. The predicted positive association between factors was likely confounded by variation in plant species composition. Specifically, sampling spanned a local gradient in plant community composition which was likely driven by niche partitioning along a subtle gradient in elevation. Our results suggest an apparent trade-off between some measures of plant biomass production and soil aggregate stability, both known to affect the land’s capacity to resist erosion. These findings further highlight the uncertainty of plant biomass-soil stability associations. PMID:27467598

Soil Aggregate Stability and Grassland Productivity Associations in a Northern Mixed-Grass Prairie.

PubMed

Reinhart, Kurt O; Vermeire, Lance T

2016-01-01

Soil aggregate stability data are often predicted to be positively associated with measures of plant productivity, rangeland health, and ecosystem functioning. Here we revisit the hypothesis that soil aggregate stability is positively associated with plant productivity. We measured local (plot-to-plot) variation in grassland community composition, plant (aboveground) biomass, root biomass, % water-stable soil aggregates, and topography. After accounting for spatial autocorrelation, we observed a negative association between % water-stable soil aggregates (0.25-1 and 1-2 mm size classes of macroaggregates) and dominant graminoid biomass, and negative associations between the % water-stable aggregates and the root biomass of a dominant sedge (Carex filifolia). However, variation in total root biomass (0-10 or 0-30 cm depths) was either negatively or not appreciably associated with soil aggregate stabilities. Overall, regression slope coefficients were consistently negative thereby indicating the general absence of a positive association between measures of plant productivity and soil aggregate stability for the study area. The predicted positive association between factors was likely confounded by variation in plant species composition. Specifically, sampling spanned a local gradient in plant community composition which was likely driven by niche partitioning along a subtle gradient in elevation. Our results suggest an apparent trade-off between some measures of plant biomass production and soil aggregate stability, both known to affect the land's capacity to resist erosion. These findings further highlight the uncertainty of plant biomass-soil stability associations.

COIN Project: Towards a zero-waste technology for concrete aggregate production in Norway

NASA Astrophysics Data System (ADS)

Cepuritis, Rolands; Willy Danielsen, Svein

2014-05-01

COIN Project: Towards a zero-waste technology for concrete aggregate production in Norway Rolands Cepuritis, Norcem/NTNU and Svein Willy Danielsen, SINTEF Aggregate production is a mining operation where no purification of the "ore" is necessary. Still it is extremely rare that an aggregate production plant is operating on the basis of zero-waste concept. This is since historically the fine crushed aggregate (particles with a size of less than 2, 4 or sometimes 8 mm) has been regarded as a by-product or waste of the more valuable coarse aggregate production. The reason is that the crushed coarse aggregates can easily replace coarse rounded natural stones in almost any concrete composition; while, the situation with the sand is different. The production of coarse aggregate normally yields fine fractions with rough surface texture, flaky or elongated particles an inadequate gradation. When such a material replaces smooth and rounded natural sand grains in a concrete mix, the result is usually poor and much more water and cement has to be used to achieve adequate concrete flow. The consequences are huge stockpiles of the crushed fine fractions that can't be sold (mass balance problems) for the aggregate producers, sustainability problems for the whole industry and environmental issues for society due to dumping and storing of the fine co-generated material. There have been attempts of utilising the material in concrete before; however, they have mostly ended up in failure. There have been attempts to adjust the crushed sand to the properties of the natural sand, which would still give a lot of waste, especially if the grading would have to be adjusted and the high amounts of fines abundantly present in the crushed sand would have to be removed. Another fundamental reason for failure has been that historically such attempts have mainly ended up in a research carried out by people (both industrial and academic) with aggregate background (= parties willing to find market

7 CFR Appendices 1, 2 and 3 to... - Dairy Tariff-Rate Import Quota Licensing

Code of Federal Regulations, 2010 CFR

2010-01-01

... 1, 2 and 3 to Subpart Agriculture Office of the Secretary of Agriculture IMPORT QUOTAS AND FEES... and 3 to Subpart—Dairy Tariff-Rate Import Quota Licensing Articles Subject to: Appendix 1, Historical Licenses; Appendix 2, Nonhistorical Licenses; and Appendix 3, Designated Importer Licenses for Quota Year...

50 CFR 635.27 - Quotas.

Code of Federal Regulations, 2013 CFR

2013-10-01

... early as feasible, the General category effort control schedule, including daily retention limits and... based on the species composition calculated from data collected by observers on non-research trips and... paragraph (b)(1) of this section. (vii) Non-blacknose small coastal sharks. The base annual commercial quota...

77 FR 19951 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-03

.... 111220786-1781-01] RIN 0648-XB103 Fisheries of the Northeastern United States; Summer Flounder Fishery... of North Carolina is transferring a portion of its 2012 commercial summer flounder quota to the... commercial summer flounder quota to the Commonwealth of Virginia. NMFS is adjusting the quotas and announcing...

21 CFR 1303.13 - Adjustments of aggregate production quotas.

Code of Federal Regulations, 2010 CFR

2010-04-01

... treatment with the class or the substances which are manufactured from it, the economic and physical availability of raw materials for use in manufacturing and for inventory purposes, yield and stability problems...

75 FR 82295 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-30

.... 0908191244-91427-02] RIN 0648-XA073 Fisheries of the Northeastern United States; Summer Flounder Fishery... of North Carolina is transferring a portion of its 2010 commercial summer flounder quota to the... summer flounder quota to the State of Rhode Island. By this action, NMFS adjusts the quotas and announces...

Effect of cocoa products and flavanols on platelet aggregation in humans: a systematic review.

PubMed

Peluso, Ilaria; Palmery, Maura; Serafini, Mauro

2015-07-01

Previous evidence suggested an active role of cocoa products and flavanols in modulating platelet aggregation. However, cocoa flavanols are characterized by a low bioavailability that can deeply affect their presence in biological fluids and raise questions on their biological effect in humans. We performed a systematic search on Medline, Embase, Cochrane and ProQuest databases, until April 2015, on the effect of cocoa products on platelet aggregation in human intervention studies. We identified 13 interventions, of which only five involved repeated administration. Different effects were observed on the basis of the platelet aggregation test used, whereas neither a longer duration of treatment nor a higher dose was associated with a higher inhibition of platelet aggregation. In conclusion, the reviewed results suggest that consumption of cocoa products in bolus administration positively affects platelet aggregation in both healthy subjects and diseased patients. On the other hand, more evidence is required in order to assess the effect of long-term cocoa product ingestion and to identify the bioactive components involved.

50 CFR 635.27 - Quotas.

Code of Federal Regulations, 2010 CFR

2010-10-01

... landings, the period of time remaining in the current fishing year, current and historical landings trends... the convenience of the user, the revised text is set forth as follows: § 635.27 Quotas. (d) Atlantic..., current and historical landings trends, and any other relevant factors, NMFS will file for publication...

50 CFR 648.290 - Individual fishing quota program and other restrictions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Individual fishing quota program and other... Management Measures for the Tilefish Fishery § 648.290 Individual fishing quota program and other restrictions. The fishing year is the 12-month period beginning with November 1, 2001. (a)Total allowable...

21 CFR 1303.22 - Procedure for applying for individual manufacturing quotas.

Code of Federal Regulations, 2010 CFR

2010-04-01

... manufacturing quotas. Any person who is registered to manufacture any basic class of controlled substance listed in Schedule I or II and who desires to manufacture a quantity of such class shall apply on DEA Form 189 for a manufacturing quota for such quantity of such class. Copies of DEA Form 189 may be obtained...

Separating full-length protein from aggregating proteolytic products using filter flow-through purification.

PubMed

Churion, Kelly A; Rogers, Robert E; Bayless, Kayla J; Bondos, Sarah E

2016-12-01

Separation of full-length protein from proteolytic products is challenging, since the properties used to isolate the protein can also be present in proteolytic products. Many separation techniques risk non-specific protein adhesion and/or require a lot of time, enabling continued proteolysis and aggregation after lysis. We demonstrate that proteolytic products aggregate for two different proteins. As a result, full-length protein can be rapidly separated from these fragments by filter flow-through purification, resulting in a substantial protein purity enhancement. This rapid approach is likely to be useful for intrinsically disordered proteins, whose repetitive sequence composition and flexible nature can facilitate aggregation. Copyright © 2016 Elsevier Inc. All rights reserved.

50 CFR 665.269 - Quotas.

Code of Federal Regulations, 2011 CFR

2011-10-01

... which it is based as soon as practicable after the determination is made. (d) Quotas for precious coral... Beds Au'au Channel Black: 5,000 2 Makapu'u Pink: 2,000 2 Gold: 0 (zero) Bamboo: 500 2 Conditional Beds... Westpac All: 0 (zero) Exploratory Area Hawaii 1,000 per area (all species combined except black corals) 1...

50 CFR 665.269 - Quotas.

Code of Federal Regulations, 2010 CFR

2010-10-01

... which it is based as soon as practicable after the determination is made. (d) Quotas for precious coral... Beds Au'au Channel Black: 5,000 2 Makapu'u Pink: 2,000 2 Gold: 0 (zero) Bamboo: 500 2 Conditional Beds... Westpac All: 0 (zero) Exploratory Area Hawaii 1,000 per area (all species combined except black corals) 1...

76 FR 46267 - Increase in Fiscal Year 2011 Specialty Sugar Tariff-Rate Quota; Determination of Total Amounts of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-02

... Tariff-Rate Quota; Determination of Total Amounts of Fiscal Year 2012 Tariff-Rate Quotas for Raw Cane... Raw Sugar Tariff- Rate Quota AGENCY: Office of the Secretary, USDA. ACTION: Notice. SUMMARY: The... year (FY) 2011 specialty sugar tariff-rate quota (TRQ) of 9,072 metric tons raw value (MTRV). The...

Administering a Solution: Goals versus Quotas

ERIC Educational Resources Information Center

Pottinger, J. Stanley

1975-01-01

Noting the federal regulations and guidelines on affirmative action, responses to them, and two Fifth Circuit Court cases regarding efficacy, propriety and constitutionality of affirmative numerical hiring relief, the Assistant U. S. Attorney General, Civil Rights Division, sketches the differences between numerical quotas and realistic goals in…

78 FR 40186 - Proposed Aggregate Production Quotas for Schedule I and II Controlled Substances and Proposed...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-03

... phenylpropanolamine, expressed in grams of anhydrous acid or base, be established as follows: Proposed 2014 Basic... grams of levo-desoxyephedrine for use in a non-controlled, non-prescription product; 2,600,000 grams for methamphetamine mostly for conversion to a schedule III product; and 61,375 grams for methamphetamine (for sale...

77 FR 24759 - Implementation of United States-Colombia Trade Promotion Agreement Tariff-Rate Quota for Imports...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-25

... Promotion Agreement Tariff-Rate Quota for Imports of Sugar AGENCY: Office of the United States Trade Representative. ACTION: Notice. SUMMARY: USTR is providing notice that the tariff-rate quota for sugar... Agreement establishes a tariff-rate quota for imports of sugar from Colombia. USTR is providing notice that...

Intracellular response to process optimization and impact on productivity and product aggregates for a high-titer CHO cell process.

PubMed

Handlogten, Michael W; Lee-O'Brien, Allison; Roy, Gargi; Levitskaya, Sophia V; Venkat, Raghavan; Singh, Shailendra; Ahuja, Sanjeev

2018-01-01

A key goal in process development for antibodies is to increase productivity while maintaining or improving product quality. During process development of an antibody, titers were increased from 4 to 10 g/L while simultaneously decreasing aggregates. Process development involved optimization of media and feed formulations, feed strategy, and process parameters including pH and temperature. To better understand how CHO cells respond to process changes, the changes were implemented in a stepwise manner. The first change was an optimization of the feed formulation, the second was an optimization of the medium, and the third was an optimization of process parameters. Multiple process outputs were evaluated including cell growth, osmolality, lactate production, ammonium concentration, antibody production, and aggregate levels. Additionally, detailed assessment of oxygen uptake, nutrient and amino acid consumption, extracellular and intracellular redox environment, oxidative stress, activation of the unfolded protein response (UPR) pathway, protein disulfide isomerase (PDI) expression, and heavy and light chain mRNA expression provided an in-depth understanding of the cellular response to process changes. The results demonstrate that mRNA expression and UPR activation were unaffected by process changes, and that increased PDI expression and optimized nutrient supplementation are required for higher productivity processes. Furthermore, our findings demonstrate the role of extra- and intracellular redox environment on productivity and antibody aggregation. Processes using the optimized medium, with increased concentrations of redox modifying agents, had the highest overall specific productivity, reduced aggregate levels, and helped cells better withstand the high levels of oxidative stress associated with increased productivity. Specific productivities of different processes positively correlated to average intracellular values of total glutathione. Additionally

Quota methods for congressional apportionment are still non-unique

PubMed Central

Mayberry, John P.

1978-01-01

Balinski and Young described a “quota method” for congressional apportionment and recommended it as “the only method satisfying three essential axioms” [Balinski, M. L. & Young, H. P. (1974) Proc. Natl. Acad. Sci. USA 71, 4602-4606]. This paper points out and repairs a slight defect in one of those axioms, producing a quota method slightly different from that described previously. It also presents an alternative to the “consistency” axiom of the paper and describes the “dual quota” method, uniquely satisfying the alternative axioms (which have exactly as much justification as the originals). PMID:16592547

77 FR 65439 - Implementation of United States-Panama Trade Promotion Agreement Tariff-Rate Quota for Imports of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-26

... Promotion Agreement Tariff-Rate Quota for Imports of Sugar AGENCY: Office of the United States Trade Representative. ACTION: Notice. SUMMARY: USTR is providing notice that the tariff-rate quotas for sugar... Agreement establishes three tariff-rate quotas for imports of sugar from Panama. USTR is providing notice...

Locally available aggregate and sediment production

Treesearch

Randy B. Foltz; Mark Truebe

2003-01-01

Selection of suitable locally available materials to build strong and durable roads with aggregate surfaces is desired to minimize road construction and maintenance costs and to minimize the detrimental effects of sedimentation. Eighteen aggregates were selected from local sources in Idaho, Oregon, South Dakota, and Washington State. Aggregate was placed in shallow...

7 CFR 1463.103 - Eligible quota holder.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Eligible quota holder. 1463.103 Section 1463.103 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS 2005-2014 TOBACCO TRANSITION PROGRAM Tobacco...

Validation of an aggregate exposure model for substances in consumer products: a case study of diethyl phthalate in personal care products

PubMed Central

Delmaar, Christiaan; Bokkers, Bas; ter Burg, Wouter; Schuur, Gerlienke

2015-01-01

As personal care products (PCPs) are used in close contact with a person, they are a major source of consumer exposure to chemical substances contained in these products. The estimation of realistic consumer exposure to substances in PCPs is currently hampered by the lack of appropriate data and methods. To estimate aggregate exposure of consumers to substances contained in PCPs, a person-oriented consumer exposure model has been developed (the Probabilistic Aggregate Consumer Exposure Model, PACEM). The model simulates daily exposure in a population based on product use data collected from a survey among the Dutch population. The model is validated by comparing diethyl phthalate (DEP) dose estimates to dose estimates based on biomonitoring data. It was found that the model's estimates compared well with the estimates based on biomonitoring data. This suggests that the person-oriented PACEM model is a practical tool for assessing realistic aggregate exposures to substances in PCPs. In the future, PACEM will be extended with use pattern data on other product groups. This will allow for assessing aggregate exposure to substances in consumer products across different product groups. PMID:25352161

78 FR 24430 - Tuna-Tariff Rate Quota; the Tariff-Rate Quota for Calendar Year 2013 Tuna Classifiable Under...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-25

..., Department of Homeland Security. ACTION: Announcement of the quota quantity of tuna in airtight containers... 1604.14.22, HTSUS, is based on the apparent United States consumption of tuna in airtight containers... containers may be entered, or withdrawn from warehouse, for consumption during the Calendar Year 2013, at the...

76 FR 27658 - Tuna-Tariff-Rate Quota; The Tariff-Rate Quota for Calendar Year 2011 Tuna Classifiable Under...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-12

... Security. ACTION: Announcement of the quota quantity of tuna in airtight containers for Calendar Year 2011... the apparent United States consumption of tuna in airtight containers during the preceding Calendar... been determined that 18,148,537 kilograms of tuna in air- tight containers may be entered and withdrawn...

77 FR 22796 - Tuna-Tariff-Rate Quota; the Tariff-Rate Quota for Calendar Year 2012 Tuna Classifiable Under...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-17

... Security. ACTION: Announcement of the quota quantity of tuna in airtight containers for Calendar Year 2012..., HTSUS, is based on the apparent United States consumption of tuna in airtight containers during the...) 863-6560. Background It has been determined that 17,270,370 kilograms of tuna in airtight containers...

76 FR 56810 - Controlled Substances: 2011 Proposed Aggregate Production Quotas

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-14

...)ethyl]-3-(1-naphthoyl)indole (JWH-200); 1-Butyl-3-(1-naphthoyl)indole (JWH-073); 1-Pentyl-3-(1-naphthoyl...]-3-(1- 45 g naphthoyl)indole (JWH-200). 1-Butyl-3-(1-naphthoyl)indole (JWH-073)..... 45 g 1-Pentyl-3...

Allocation and simulation study of carbon emission quotas among China's provinces in 2020.

PubMed

Zhou, Xing; Guan, Xueling; Zhang, Ming; Zhou, Yao; Zhou, Meihua

2017-03-01

China will form its carbon market in 2017 to focus on the allocation of regional carbon emission quota in order to cope with global warming. The rationality of the regional allocation has become an important consideration for the government in ensuring stable growth in different regions that are experiencing disparity in resource endowment and economic status. Based on constructing the quota allocation indicator system for carbon emission, the emission quota for each province in different scenarios and schemes in 2020 is simulated by the multifactor hybrid weighted Shannon entropy allocation model. The following conclusions are drawn: (1) The top 5 secondary-level indicators that influence provincial quota allocation in weight are as follows: per capita energy consumption, openness, per capita carbon emission, per capita disposable income, and energy intensity. (2) The ratio of carbon emission in 2020 is different from that in 2013 in many scenarios, and the variation is scenario 2 > scenario 1 > scenario 3, with Hubei and Guangdong the provinces with the largest increase and decrease ratios, respectively. (3) In the same scenario, the quota allocation varies in different reduction criteria emphases; if the government emphasizes reduction efficiency, scheme 1 will show obvious adjustment, that is, Hunan, Hubei, Guizhou, and Yunnan will have the largest decrease. The amounts are 4.28, 8.31, 4.04, and 5.97 million tons, respectively.

21 CFR 1315.21 - Individual manufacturing quotas.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Individual manufacturing quotas. 1315.21 Section 1315.21 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND... for and issue to each person registered to manufacture in bulk ephedrine, pseudoephedrine, or...

21 CFR 1315.21 - Individual manufacturing quotas.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Individual manufacturing quotas. 1315.21 Section 1315.21 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND... for and issue to each person registered to manufacture in bulk ephedrine, pseudoephedrine, or...

21 CFR 1315.21 - Individual manufacturing quotas.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Individual manufacturing quotas. 1315.21 Section 1315.21 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND... for and issue to each person registered to manufacture in bulk ephedrine, pseudoephedrine, or...

21 CFR 1315.21 - Individual manufacturing quotas.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Individual manufacturing quotas. 1315.21 Section 1315.21 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND... for and issue to each person registered to manufacture in bulk ephedrine, pseudoephedrine, or...

21 CFR 1315.21 - Individual manufacturing quotas.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Individual manufacturing quotas. 1315.21 Section 1315.21 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND... for and issue to each person registered to manufacture in bulk ephedrine, pseudoephedrine, or...

50 CFR 680.40 - Crab Quota Share (QS), Processor QS (PQS), Individual Fishing Quota (IFQ), and Individual...

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Crab Quota Share (QS), Processor QS (PQS... established based on the regional designations determined on August 1, 2005. QS or PQS issued after this date... information is true, correct, and complete to the best of his/her knowledge and belief. If the application is...

Method for the production of cementitious compositions and aggregate derivatives from said compositions

DOEpatents

Minnick, L. John

1981-01-01

Method for the production of cementitious compositions and aggregate derivatives of said compositions, and cementitious compositions and aggregates produced by said method, wherein fluidized bed combustion residue and pozzolanic material, such as pulverized coal combustion system fly ash, are incorporated in a cementitious mix. The mix is cast into desired shape and cured. If desired, the shape may then be crushed so as to result in a fluidized bed combustion residue-fly ash aggregate material or the shape may be used by itself.

78 FR 77005 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-20

.... 121009528-2729-02] RIN 0648-XD021 Fisheries of the Northeastern United States; Summer Flounder Fishery... commercial summer flounder quotas to the Commonwealth of Massachusetts. NMFS is adjusting the quotas and.... SUPPLEMENTARY INFORMATION: Regulations governing the summer flounder fishery are in 50 CFR part 648, and require...

76 FR 21418 - Fiscal Year 2011 Allocation of Additional Tariff-Rate Quota Volume for Raw Cane Sugar and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-15

...-Rate Quota Volume for Raw Cane Sugar and Reallocation of Unused Fiscal Year 2011 Tariff-Rate Quota Volume for Raw Cane Sugar AGENCY: Office of the United States Trade Representative. ACTION: Notice...) for imported raw cane sugar and of country-by-country reallocations of the FY 2011 in-quota quantity...

77 FR 25012 - Fiscal Year 2012 Allocation of Additional Tariff-Rate Quota Volume for Raw Cane Sugar and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-26

...-Rate Quota Volume for Raw Cane Sugar and Reallocation of Unused Fiscal Year 2012 Tariff-Rate Quota Volume for Raw Cane Sugar AGENCY: Office of the United States Trade Representative. ACTION: Notice...) for imported raw cane sugar and of country-by-country reallocations of the FY 2012 in-quota quantity...

76 FR 60801 - Assessment of Fees for Dairy Import Licenses for the 2012 Tariff-Rate Import Quota Year

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-30

... Licenses for the 2012 Tariff- Rate Import Quota Year AGENCY: Foreign Agricultural Service, USDA. ACTION: Notice. SUMMARY: This notice announces a fee of $170 to be charged for the 2012 tariff-rate quota (TRQ...) authorizing the importation of certain dairy articles, which are subject to tariff-rate quotas set forth in...

78 FR 25003 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-29

.... 121009528-2729-02] RIN 0648-XC634 Fisheries of the Northeastern United States; Summer Flounder Fishery... of North Carolina is transferring a portion of its 2013 commercial summer flounder quota to the... transferring a portion of its 2013 commercial summer flounder quota to the Commonwealth of Massachusetts and to...

77 FR 73556 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-11

.... 111220786-1781-01] RIN 0648-XC373 Fisheries of the Northeastern United States; Summer Flounder Fishery... of Maine is transferring a portion of its 2012 commercial summer flounder quota to the State of... summer flounder fishery are in 50 CFR part 648, and require annual specification of a commercial quota...

78 FR 66857 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-07

.... 121009528-2729-02] RIN 0648-XC932 Fisheries of the Northeastern United States; Summer Flounder Fishery... of Maine is transferring a portion of its 2013 commercial summer flounder quota to the State of... summer flounder fishery are in 50 CFR part 648, and require annual specification of a commercial quota...

75 FR 53271 - Assessment of Fees for Dairy Import Licenses for the 2011 Tariff-Rate Import Quota Year

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-31

... Service Assessment of Fees for Dairy Import Licenses for the 2011 Tariff- Rate Import Quota Year AGENCY... charged for the 2011 tariff-rate quota (TRQ) year for each license issued to a person or firm by the U.S... tariff-rate quotas set forth in the Harmonized Tariff Schedule (HTS) of the United States. DATES...

Extracellular Polymeric Substance Production and Aggregated Bacteria Colonization Influence the Competition of Microbes in Biofilms.

PubMed

Jayathilake, Pahala G; Jana, Saikat; Rushton, Steve; Swailes, David; Bridgens, Ben; Curtis, Tom; Chen, Jinju

2017-01-01

The production of extracellular polymeric substance (EPS) is important for the survival of biofilms. However, EPS production is costly for bacteria and the bacterial strains that produce EPS (EPS+) grow in the same environment as non-producers (EPS-) leading to competition between these strains for nutrients and space. The outcome of this competition is likely to be dependent on factors such as initial attachment, EPS production rate, ambient nutrient levels and quorum sensing. We use an Individual-based Model (IbM) to study the competition between EPS+ and EPS- strains by varying the nature of initial colonizers which can either be in the form of single cells or multicellular aggregates. The microbes with EPS+ characteristics obtain a competitive advantage if they initially colonize the surface as smaller aggregates and are widely spread-out between the cells of EPS-, when both are deposited on the substratum. Furthermore, the results show that quorum sensing-regulated EPS production may significantly reduce the fitness of EPS producers when they initially deposit as aggregates. The results provide insights into how the distribution of bacterial aggregates during initial colonization could be a deciding factor in the competition among different strains in biofilms.

50 CFR 648.291 - Individual fishing quota.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Individual fishing quota. 648.291 Section... vessel with a fishing history that includes a valid tilefish limited access permit for the 2005 permit year and reported landings of tilefish from 2001 through 2005 that constituted at least 0.5 percent of...

78 FR 78786 - Fisheries of the Northeastern United States; 2014 Commercial Summer Flounder Quota Adjustments

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-27

.... 121009528-2729-02] RIN 0648-XD026 Fisheries of the Northeastern United States; 2014 Commercial Summer... Atmospheric Administration (NOAA), Commerce. ACTION: Announcement of 2014 commercial summer flounder state quotas. SUMMARY: NMFS is announcing the commercial summer flounder state quotas for fishing year 2014...

78 FR 48193 - Final Adjusted Aggregate Production Quotas for Schedule I and II Controlled Substances and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-07

... needs for the List I chemicals ephedrine, pseudoephedrine, and phenylpropanolamine, expressed in grams...,000 g Methamphetamine 3,912,500 g [987,500 grams of levo-desoxyephedrine for use in a non-controlled, non- prescription product; 2,863,750 grams for methamphetamine mostly for conversion to a schedule III...

76 FR 15276 - Atlantic Highly Migratory Species; Atlantic Bluefin Tuna Quotas and Atlantic Tuna Fisheries...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-21

.... 110210132-1133-01] RIN 0648-BA65 Atlantic Highly Migratory Species; Atlantic Bluefin Tuna Quotas and Atlantic Tuna Fisheries Management Measures; Correction AGENCY: National Marine Fisheries Service (NMFS... 14, 2011, NMFS published a proposed rule to modify Atlantic bluefin tuna (BFT) base quotas for all...

50 CFR 648.291 - Individual fishing quota.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 10 2011-10-01 2011-10-01 false Individual fishing quota. 648.291 Section... tilefish limited access permit for the 2005 permit year and reported landings of tilefish from 2001 through 2005 that constituted at least 0.5 percent of the total landings in the tilefish Category for which it...

Lightweight aggregate production from claystone and shale in Bangladesh

USGS Publications Warehouse

Parker, Norbert A.; Khan, M.A.

1976-01-01

Muffle furnace tests were made on samples of clay, claystone, and shale collected in the Chittagong and Dacca areas of East Pakistan to determine their amenability to bloating for the commercial production of light-weight aggregate. Several areas, sampled in some detail, were selected for investigation because of their proximity to market, and accessibility to fuel and electricity. Muffle furnace tests show that the clay, claystone, and shale are natural bloaters at temperatures in the 1700? to 2200? F range, and do not require additives. The most desirable deposit, insofar as producing a strong aggregate is concerned, can be determined only by pilot-kiln testing and by crushing-strength tests made on concrete test cylinders. Reserves of suitable raw material are large in both the Chittagong and Dacca areas.

75 FR 50796 - Fiscal Year 2011 Tariff-Rate Quota Allocations for Raw Cane Sugar, Refined and Specialty Sugar...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-17

... for Raw Cane Sugar, Refined and Specialty Sugar, and Sugar-Containing Products AGENCY: Office of the... quantity of the tariff-rate quotas for imported raw cane sugar, refined and specialty sugar, and sugar... imports of raw cane sugar and refined sugar. Pursuant to Additional U.S. Note 8 to Chapter 17 of the HTS...

Hydroxychavicol, a novel betel leaf component, inhibits platelet aggregation by suppression of cyclooxygenase, thromboxane production and calcium mobilization.

PubMed

Chang, M C; Uang, B J; Tsai, C Y; Wu, H L; Lin, B R; Lee, C S; Chen, Y J; Chang, C H; Tsai, Y L; Kao, C J; Jeng, J H

2007-09-01

Platelet hyperactivity is important in the pathogenesis of cardiovascular diseases. Betel leaf (PBL) is consumed by 200-600 million betel quid chewers in the world. Hydroxychavicol (HC), a betel leaf component, was tested for its antiplatelet effect. We tested the effect of HC on platelet aggregation, thromboxane B(2) (TXB(2)) and reactive oxygen species (ROS) production, cyclooxygenase (COX) activity, ex vivo platelet aggregation and mouse bleeding time and platelet plug formation in vivo. The pharmacokinetics of HC in rats was also assessed. HC inhibited arachidonic acid (AA) and collagen-induced platelet aggregation and TXB(2) production. HC inhibited the thrombin-induced TXB(2) production, but not platelet aggregation. SQ29548, suppressed collagen- and thrombin-induced TXB(2) production, but not thrombin-induced platelet aggregation. HC also suppressed COX-1/COX-2 enzyme activity and the AA-induced ROS production and Ca(2+) mobilization. HC further inhibited the ex vivo platelet aggregation of platelet-rich plasma (>100 nmole/mouse) and prolonged platelet plug formation (>300 nmole/mouse) in mesenteric microvessels, but showed little effect on bleeding time in mouse tail. Moreover, pharmacokinetics analysis found that more than 99% of HC was metabolized within 3 min of administration in Sprague-Dawley rats in vivo. HC is a potent COX-1/COX-2 inhibitor, ROS scavenger and inhibits platelet calcium signaling, TXB(2) production and aggregation. HC could be a potential therapeutic agent for prevention and treatment of atherosclerosis and other cardiovascular diseases through its anti-inflammatory and antiplatelet effects, without effects on haemostatic functions.

76 FR 36892 - Atlantic Highly Migratory Species; 2011 North and South Atlantic Swordfish Quotas

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-23

... Atlantic Tunas (ICCAT) recommendations 10-02 and 09-03 into the quota adjustments for the 2011 fishing year... adopted for North Atlantic Swordfish for one year. Recommendation 10-02 included a total TAC of 13,700 mt... year. Recommendation 10-02 maintains the U.S. previous years' quota allocation of 2,937.6 mt dw as well...

76 FR 18504 - Atlantic Highly Migratory Species; Atlantic Bluefin Tuna Quotas and Atlantic Tuna Fisheries...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-04

...-BA65 Atlantic Highly Migratory Species; Atlantic Bluefin Tuna Quotas and Atlantic Tuna Fisheries..., 2011, NMFS published a proposed rule to modify Atlantic bluefin tuna (BFT) base quotas for all domestic...); amend the Atlantic tunas possession at sea and landing regulations to allow removal of Atlantic tunas...

77 FR 62495 - Fisheries of the Northeastern United States; Tilefish Fishery; 2013 Tilefish Fishing Quota...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-15

... the Northeastern United States; Tilefish Fishery; 2013 Tilefish Fishing Quota Specification AGENCY.... ACTION: Notice. SUMMARY: NMFS announces that the overall annual tilefish quota for the 2013 fishing year (November 1, 2012-October 31, 2013) will remain the same as it was in fishing year 2012. NMFS is required to...

77 FR 6492 - Fisheries of the Exclusive Economic Zone Off Alaska; Community Development Quota Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-08

... CDQ allocation process, the transfer of groundfish CDQ and halibut prohibited species quota, and the.... 679.2, Removing all regulations in Sec. 679.30 (except paragraph (e)(1) related to quota transfers... PSQ catch limits. However, it will amend regulations to allow the transfer of halibut PSQ either...

Production of mineral aggregates in quartz tumbling experiments

NASA Astrophysics Data System (ADS)

Nørnberg, Per; Finster, Kai; Pall Gunnlaugsson, Haraldur; Knak Jensen, Svend; Merrison, Jonathan Peter

2013-04-01

Introduction Tumbling experiments with quartz sand with the purpose of tracing the effect of broken bonds in mineral surfaces resulted in an unexpected production of aggregates. These aggregates are a few microns in diameter, spherical and resembling tiny white "snowballs." Particle comminution by aeolian and other natural weathering processes are known in soil science and is often seen as an increase of fine particles towards the top of soil profiles (Nørnberg, P. 1987, 1988, 2002, J.S. Wright 2007). When mineral grains collide in aeolian processes they break up along weakness zones in the crystal lattice. This mechanism causes broken bonds between atoms in the crystal lattice and results in reactive groups in the mineral surface. This mechanism provides the background for experiments to investigate the oxidation processes of magnetite on the planet Mars. The primary magnetic iron oxide phase on Mars is to day known to be magnetite and the colour of the dust on Mars is most likely due to hematite. To investigate if the oxidation process could take place without going over dissolution and precipitation in water, experiments with tumbling of quartz grains in sealed glass containers along with magnetite were started. The idea was that activated bonds at the surface of quartz could oxidize magnetite and convert it to hematite over time. This proved to be the case (Merrison, J.P. et al. 2010). However, in these experiments we observed the formation of the white aggregates which has been the subject of the study that we present here. Results of tumbling experiments Commercially available quarts (Merck) was sieved to obtain the fraction between 125 and 1000 µm. This fraction was tumbled in glass containers for months and resulted in production of a significant amount of fine grained material (Merrison, J.P et al. 2010). A part of this fine fraction consists of the "snowball"-like aggregates which is a fragile element with relatively high specific surface. The physical

Hydroxychavicol, a novel betel leaf component, inhibits platelet aggregation by suppression of cyclooxygenase, thromboxane production and calcium mobilization

PubMed Central

Chang, M C; Uang, B J; Tsai, C Y; Wu, H L; Lin, B R; Lee, C S; Chen, Y J; Chang, C H; Tsai, Y L; Kao, C J; Jeng, J H

2007-01-01

Background and purpose: Platelet hyperactivity is important in the pathogenesis of cardiovascular diseases. Betel leaf (PBL) is consumed by 200-600 million betel quid chewers in the world. Hydroxychavicol (HC), a betel leaf component, was tested for its antiplatelet effect. Experimental approach: We tested the effect of HC on platelet aggregation, thromboxane B2 (TXB2) and reactive oxygen species (ROS) production, cyclooxygenase (COX) activity, ex vivo platelet aggregation and mouse bleeding time and platelet plug formation in vivo. The pharmacokinetics of HC in rats was also assessed. Key results: HC inhibited arachidonic acid (AA) and collagen-induced platelet aggregation and TXB2 production. HC inhibited the thrombin-induced TXB2 production, but not platelet aggregation. SQ29548, suppressed collagen- and thrombin-induced TXB2 production, but not thrombin-induced platelet aggregation. HC also suppressed COX-1/COX-2 enzyme activity and the AA-induced ROS production and Ca2+ mobilization. HC further inhibited the ex vivo platelet aggregation of platelet-rich plasma (>100 nmole/mouse) and prolonged platelet plug formation (>300 nmole/mouse) in mesenteric microvessels, but showed little effect on bleeding time in mouse tail. Moreover, pharmacokinetics analysis found that more than 99% of HC was metabolized within 3 min of administration in Sprague-Dawley rats in vivo. Conclusions and implications: HC is a potent COX-1/COX-2 inhibitor, ROS scavenger and inhibits platelet calcium signaling, TXB2 production and aggregation. HC could be a potential therapeutic agent for prevention and treatment of atherosclerosis and other cardiovascular diseases through its anti-inflammatory and antiplatelet effects, without effects on haemostatic functions. PMID:17641677

76 FR 61074 - USDA Increases the Fiscal Year 2011 Tariff-Rate Quota for Refined Sugar

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-03

... Quota for Refined Sugar AGENCY: Office of the Secretary, USDA. ACTION: Notice. SUMMARY: The Secretary of Agriculture today announced an increase in the fiscal year (FY) 2011 refined sugar tariff-rate quota (TRQ) of... INFORMATION: A quantity of 22,000 MTRV for sugars, syrups, and molasses (collectively referred to as refined...

Applying linear programming model to aggregate production planning of coated peanut products

NASA Astrophysics Data System (ADS)

Rohmah, W. G.; Purwaningsih, I.; Santoso, EF S. M.

2018-03-01

The aim of this study was to set the overall production level for each grade of coated peanut product to meet market demands with a minimum production cost. The linear programming model was applied in this study. The proposed model was used to minimize the total production cost based on the limited demand of coated peanuts. The demand values applied to the method was previously forecasted using time series method and production capacity aimed to plan the aggregate production for the next 6 month period. The results indicated that the production planning using the proposed model has resulted a better fitted pattern to the customer demands compared to that of the company policy. The production capacity of product family A, B, and C was relatively stable for the first 3 months of the planning periods, then began to fluctuate over the next 3 months. While, the production capacity of product family D and E was fluctuated over the 6-month planning periods, with the values in the range of 10,864 - 32,580 kg and 255 – 5,069 kg, respectively. The total production cost for all products was 27.06% lower than the production cost calculated using the company’s policy-based method.

Use of a Generalized Additive Model to Investigate Key Abiotic Factors Affecting Microcystin Cellular Quotas in Heavy Bloom Areas of Lake Taihu

PubMed Central

Tao, Min; Xie, Ping; Chen, Jun; Qin, Boqiang; Zhang, Dawen; Niu, Yuan; Zhang, Meng; Wang, Qing; Wu, Laiyan

2012-01-01

Lake Taihu is the third largest freshwater lake in China and is suffering from serious cyanobacterial blooms with the associated drinking water contamination by microcystin (MC) for millions of citizens. So far, most studies on MCs have been limited to two small bays, while systematic research on the whole lake is lacking. To explain the variations in MC concentrations during cyanobacterial bloom, a large-scale survey at 30 sites across the lake was conducted monthly in 2008. The health risks of MC exposure were high, especially in the northern area. Both Microcystis abundance and MC cellular quotas presented positive correlations with MC concentration in the bloom seasons, suggesting that the toxic risks during Microcystis proliferations were affected by variations in both Microcystis density and MC production per Microcystis cell. Use of a powerful predictive modeling tool named generalized additive model (GAM) helped visualize significant effects of abiotic factors related to carbon fixation and proliferation of Microcystis (conductivity, dissolved inorganic carbon (DIC), water temperature and pH) on MC cellular quotas from recruitment period of Microcystis to the bloom seasons, suggesting the possible use of these factors, in addition to Microcystis abundance, as warning signs to predict toxic events in the future. The interesting relationship between macrophytes and MC cellular quotas of Microcystis (i.e., high MC cellular quotas in the presence of macrophytes) needs further investigation. PMID:22384128

A study in cost analysis of aggregate production as depending on drilling and blasting design

NASA Astrophysics Data System (ADS)

Bilim, Niyazi; Çelik, Arif; Kekeç, Bilgehan

2017-10-01

Since aggregate production has vital importance for many engineering projects-such as construction, highway and plant-mixed concrete production-this study was undertaken to determine how the costs for such production are affected by the design of drilling and blasting processes used. Aggregates are used in the production of concrete and asphalt, which are critical resources for the construction sector. The ongoing population increase and the growth of living standards around the world drive the increasing demand for these products. As demand grows, competition has naturally arisen among producers in the industry. Competition in the market has directly affected prices, which leads to the need for new measures and cost analysis on production costs. The cost calculation is one of the most important parameters in mining activities. Aggregate production operations include drilling, blasting, secondary crushing (if necessary), loading, hauling and crushing-screening, and each of these factors affects cost. In this study, drilling and blasting design parameters (such as hole diameter, hole depth, hole distance and burden) were investigated and evaluated for their effect on the total cost of quarrying these products, based on a particular quarry selected for this research. As the result of evaluation, the parameters actually driving costs have been identified, and their effects on the cost have been determined. In addition, some suggestions are presented regarding production design which may lead to avoiding increased production costs.

Utilization of lignite power generation residues for the production of lightweight aggregates.

PubMed

Anagnostopoulos, Iason M; Stivanakis, Victor E

2009-04-15

A novel process is proposed for the utilization of lignite combustion solid residues in the production of inflammable lightweight aggregates (LWA). The process consists of two stages, pelletization and sintering, and carbon contained in BA was used as the process fuel. The main residues bottom ash (BA) and fly ash (FA) from Megalopolis power plant were characterized, mixed in different proportions and treated through pelletization and sintering process. Sintering benefits from combustion of BA carbon content and the product is a hardened porous cake. The energy required for achievement of high temperatures, in the range of 1250 degrees C, was offered by carbon combustion and CO(2) evolution is responsible for porous structure formation. Selected physical properties of sintered material relevant to use as lightweight aggregates were determined, including bulk density, porosity and water absorption. Bulk density varies from 0.83 to 0.91 g/cm(3), porosity varies from 60% to 64% and water absorption varies from 66% to 80%. LWA formed is used for the production of lightweight aggregate concrete (LWAC). Thermal conductivity coefficient varies from 0.25 to 0.37 W/mK (lower than maximum limit 0.43 W/mK) and compressive strength varies from 19 to 23 MPa (higher than minimum limit 17 MPa). The results indicate that sintering of lignite combustion residues is an efficient method of utilization of carbon containing BA and production of LWA for structural and insulating purposes. Carbon content of BA is a key factor in LWA production. Finally, this research work comprises the first proposed application for utilization of BA in Greece.

78 FR 12705 - Atlantic Highly Migratory Species; North and South Atlantic 2013 Commercial Swordfish Quotas

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-25

... dead discards. We will adjust the quotas in the final rule based on updated data, including dead... quota, the sum of updated landings data (from late reports) and dead discard estimates would need to reach or exceed 475 mt dw. In 2011, dead discards were estimated to equal 101.5 mt dw and late reports...

76 FR 13583 - Atlantic Highly Migratory Species; Atlantic Bluefin Tuna Quotas and Atlantic Tuna Fisheries...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-14

... dead discards as well as the amount of 2010 underharvest (of 2010 adjusted quota) allowed by ICCAT to... would adjust these base quotas for the 2012 fishing year based on the best estimate of dead discards and... early 2012). As described below, 160 mt is used as a proxy for dead discards based on the 2009 estimate...

A novel heuristic for optimization aggregate production problem: Evidence from flat panel display in Malaysia

NASA Astrophysics Data System (ADS)

Al-Kuhali, K.; Hussain M., I.; Zain Z., M.; Mullenix, P.

2015-05-01

Aim: This paper contribute to the flat panel display industry it terms of aggregate production planning. Methodology: For the minimization cost of total production of LCD manufacturing, a linear programming was applied. The decision variables are general production costs, additional cost incurred for overtime production, additional cost incurred for subcontracting, inventory carrying cost, backorder costs and adjustments for changes incurred within labour levels. Model has been developed considering a manufacturer having several product types, which the maximum types are N, along a total time period of T. Results: Industrial case study based on Malaysia is presented to test and to validate the developed linear programming model for aggregate production planning. Conclusion: The model development is fit under stable environment conditions. Overall it can be recommended to adapt the proven linear programming model to production planning of Malaysian flat panel display industry.

Application of first order rate kinetics to explain changes in bloom toxicity—the importance of understanding cell toxin quotas

NASA Astrophysics Data System (ADS)

Orr, Philip T.; Willis, Anusuya; Burford, Michele A.

2018-04-01

Cyanobacteria are oxygenic photosynthetic Gram-negative bacteria that can form potentially toxic blooms in eutrophic and slow flowing aquatic ecosystems. Bloom toxicity varies spatially and temporally, but understanding the mechanisms that drive these changes remains largely a mystery. Changes in bloom toxicity may result from changes in intracellular toxin pool sizes of cyanotoxins with differing molecular toxicities, and/or from changes in the cell concentrations of toxic and non-toxic cyanobacterial species or strains within bloom populations. We show here how first-order rate kinetics at the cellular level can be used to explain how environmental conditions drive changes in bloom toxicity at the ecological level. First order rate constants can be calculated for changes in cell concentration (μ c: specific cell division rate) or the volumetric biomass concentration (μ g: specific growth rate) between short time intervals throughout the cell cycle. Similar first order rate constants can be calculated for changes in nett volumetric cyanotoxin concentration (μ tox: specific cyanotoxin production rate) over similar time intervals. How μ c (or μ g ) covaries with μ tox over the cell cycle shows conclusively when cyanotoxins are being produced and metabolised, and how the toxicity of cells change in response to environment stressors. When μ tox/μ c>1, cyanotoxin cell quotas increase and individual cells become more toxic because the nett cyanotoxin production rate is higher than the cell division rate. When μ tox/μ c=1, cell cyanotoxin quotas remains fixed because the nett cyanotoxin production rate matches the cell division rate. When μ tox/μ c<1, the cyanotoxin cell quota decreases because either the nett cyanotoxin production rate is lower than the cell division rate, or metabolic breakdown and/or secretion of cyanotoxins is occurring. These fundamental equations describe cyanotoxin metabolism dynamics at the cellular level and provide the necessary

Non-Arrhenius protein aggregation.

PubMed

Wang, Wei; Roberts, Christopher J

2013-07-01

Protein aggregation presents one of the key challenges in the development of protein biotherapeutics. It affects not only product quality but also potentially impacts safety, as protein aggregates have been shown to be linked with cytotoxicity and patient immunogenicity. Therefore, investigations of protein aggregation remain a major focus in pharmaceutical companies and academic institutions. Due to the complexity of the aggregation process and temperature-dependent conformational stability, temperature-induced protein aggregation is often non-Arrhenius over even relatively small temperature windows relevant for product development, and this makes low-temperature extrapolation difficult based simply on accelerated stability studies at high temperatures. This review discusses the non-Arrhenius nature of the temperature dependence of protein aggregation, explores possible causes, and considers inherent hurdles for accurately extrapolating aggregation rates from conventional industrial approaches for selecting accelerated conditions and from conventional or more advanced methods of analyzing the resulting rate data.

75 FR 1589 - Amendment of Limitation of Duty- and Quota-Free Imports of Apparel Articles Assembled in...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-12

...-Free Imports of Apparel Articles Assembled in Beneficiary ATPDEA Countries From Regional Country Fabric... for duty- and quota-free treatment for certain textile and apparel articles imported from designated...) of the amended ATPA provides duty- and quota-free treatment for certain apparel articles assembled in...

Data on optimum recycle aggregate content in production of new structural concrete.

PubMed

Paul, Suvash Chandra

2017-12-01

This data presented herein are the research summary of "mechanical behavior and durability performance of concrete containing recycled concrete aggregate" (Paul, 2011) [1]. The results reported in this article relate to an important parameter of optimum content of recycle concrete aggregate (RCA) in production of new concrete for both structural and non-structural applications. For the purpose of the research various types of physical, mechanical and durability tests are performed for concrete made with different percentages of RCA. Therefore, this data set can be a great help of the readers to understand the mechanism of RCA in relates to the concrete properties.

Aggregate consumer exposure to UV filter ethylhexyl methoxycinnamate via personal care products.

PubMed

Manová, Eva; von Goetz, Natalie; Hungerbuehler, Konrad

2015-01-01

Ultraviolet (UV) filters are substances designed to protect our skin from UV-induced damage and can be found in many categories of personal care products (PCPs). The potential endocrine-disrupting effects attributed to UV filter ethylhexyl methoxycinnamate (EHMC) are being debated. We evaluated the aggregate exposure of the Swiss-German population (N=1196; ages ≤1-97years) to EHMC via the use of PCPs; thus we provide the first comprehensive information about the current EHMC exposure sources and aggregate exposure levels. In our probabilistic modeling method performed at an individual level, PCP use data obtained by a postal questionnaire were linked to concentration data on EHMC gained from chemical analyses of PCPs used by the questionnaire respondents. The modeled median and 99.9th percentile of the internal aggregate exposure for the general population were 0.012 and 0.873mgday(-1)kg(-1) and 0.008 and 0.122mgday(-1)kg(-1) for the summer/autumn and winter/spring period, respectively. The major contributors to internal aggregate exposure were sunscreen products in summer/autumn (females: 64%; males: 85%; children aged ≤12years 93%). In winter/spring, lip care dominated for females (30%) and sunscreen for males (38%) and children aged ≤12years (50%). Overall, the internal aggregate exposure estimates for the studied population are shown to be below the Derived No Effect Level (DNEL) for EHMC i.e., the level of exposure above which humans should not be exposed; however, when an intense short-term exposure via sunscreen is accounted for during a sunbathing day, at the high-end percentiles (99.9th) the predicted aggregate exposure exceeds the DNEL for thyroid-disrupting effects such as for children aged ≤4years, who might be particularly susceptible to endocrine disrupting events. It is nevertheless critical to acknowledge that quantitative data on transdermal penetration of EHMC from PCPs are currently insufficient. Since long-term effects of endocrine

Results of physician licence examination and scholarship contract compliance by the graduates of regional quotas in Japanese medical schools: a nationwide cross-sectional survey

PubMed Central

Matsumoto, Masatoshi; Takeuchi, Keisuke; Owaki, Tetsuhiro; Iguchi, Seitaro; Inoue, Kazuo; Kashima, Saori; Tazuma, Susumu; Maeda, Takahiro

2017-01-01

Objectives Responding to the serious shortage of physicians in rural areas, the Japanese government has aggressively increased the number of entrants to medical schools since 2008, mostly as a chiikiwaku, entrants filling a regional quota. The quota has spread to most medical schools, and these entrants occupied 16% of all medical school seats in 2016. Most of these entrants were admitted to medical school with a scholarship with the understanding that after graduation they will practise in designated areas of their home prefectures for several years. The quota and scholarship programmes will be revised by the government starting in 2018. This study evaluates the intermediate outcomes of these programmes. Design Cross-sectional survey to all prefectural governments and medical schools every year from 2014 to 2017 to obtain data on medical graduates. Settings Nationwide. Participants All quota and non-quota graduates with prefecture scholarship in each prefecture, and all the quota graduates without scholarship in each medical school. Primary outcome measures Passing rate of the National License Examination for Physicians and the percentage of graduates who have not bought out the scholarship contract after graduation. Results Most prefectures and medical schools in Japan participated in this study (97.8%–100%). Quota graduates with scholarship were significantly more likely to pass the National License Examination for Physicians than the other medical graduates in Japan at all the years (97.9%, 96.7%, 97.4% and 94.7% vs 93.9%, 94.5%, 94.3% and 91.8%, respectively). The percentage of quota graduates with scholarship who remained in the scholarship contract 3 years after graduation was 92.2% and 89.9% for non-quota graduates with scholarship. Conclusions Quota entrants showed better academic performance than their peers. Most of the quota graduates remained in the contractual workforce. The imminent revision of the national policy regarding quota and scholarship

75 FR 60067 - Limitations of Duty- and Quota-Free Imports of Apparel Articles Assembled in Beneficiary Sub...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-29

... COMMITTEE FOR THE IMPLEMENTATION OF TEXTILE AGREEMENTS Limitations of Duty- and Quota-Free Imports... New 12-Month Cap on Duty- and Quota-Free Benefits. DATES: Effective Date: October 1, 2010. FOR FURTHER... 2004, Pub. L. 108-274; Division D, Title VI, section 6002 of the Tax Relief and Health Care Act of 2006...

Marine Synechococcus Aggregation

NASA Astrophysics Data System (ADS)

Neuer, S.; Deng, W.; Cruz, B. N.; Monks, L.

2016-02-01

Cyanobacteria are considered to play an important role in the oceanic biological carbon pump, especially in oligotrophic regions. But as single cells are too small to sink, their carbon export has to be mediated by aggregate formation and possible consumption by zooplankton producing sinking fecal pellets. Here we report results on the aggregation of the ubiquitous marine pico-cyanobacterium Synechococcus as a model organism. We first investigated the mechanism behind such aggregation by studying the potential role of transparent exopolymeric particles (TEP) and the effects of nutrient (nitrogen or phosphorus) limitation on the TEP production and aggregate formation of these pico-cyanobacteria. We further studied the aggregation and subsequent settling in roller tanks and investigated the effects of the clays kaolinite and bentonite in a series of concentrations. Our results show that despite of the lowered growth rates, Synechococcus in nutrient limited cultures had larger cell-normalized TEP production, formed a greater volume of aggregates, and resulted in higher settling velocities compared to results from replete cultures. In addition, we found that despite their small size and lack of natural ballasting minerals, Synechococcus cells could still form aggregates and sink at measureable velocities in seawater. Clay minerals increased the number and reduced the size of aggregates, and their ballasting effects increased the sinking velocity and carbon export potential of aggregates. In comparison with the Synechococcus, we will also present results of the aggregation of the pico-cyanobacterium Prochlorococcus in roller tanks. These results contribute to our understanding in the physiology of marine Synechococcus as well as their role in the ecology and biogeochemistry in oligotrophic oceans.

Diatom aggregation and dimethylsulfide production in phytoplankton blooms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crocker, K.M.

1994-01-01

Phytoplankton blooms are crucial links in many of the earth's biogeochemical cycles. Blooms take up atmospheric carbon through photosynthesis, and sequester it on the ocean floor by sinking. Aggregation of single cells into [open quote]marine snow[close quote] particles speeds up the sinking of algal cells. Laboratory studies investigating the process of aggregation show that some species have a higher probability of aggregating than others, and that there exist several mechanisms for causing aggregation. Field studies confirm that some species are more likely to be found in aggregates than in the surrounding seawater. High latitude Premnesiophyte blooms are found to producemore » large amounts of dimethylsulflde (DMS), believed to be an important chemical in global thermoregulation. DMS is found to vary diurnally, possibly due to photooxidation by ultraviolet light. This possibility links the effects of DMS on cloud formation with the effects of increased ultraviolet light penetrating the earths ozone layer.« less

Oil-Price Shocks: Beyond Standard Aggregate Demand/Aggregate Supply Analysis.

ERIC Educational Resources Information Center

Elwood, S. Kirk

2001-01-01

Explores the problems of portraying oil-price shocks using the aggregate demand/aggregate supply model. Presents a simple modification of the model that differentiates between production and absorption of goods, which enables it to better reflect the effects of oil-price shocks on open economies. (RLH)

Cold rescue of the thermolabile tailspike intermediate at the junction between productive folding and off-pathway aggregation.

PubMed Central

Betts, S. D.; King, J.

1998-01-01

Off-pathway intermolecular interactions between partially folded polypeptide chains often compete with correct intramolecular interactions, resulting in self-association of folding intermediates into the inclusion body state. Intermediates for both productive folding and off-pathway aggregation of the parallel beta-coil tailspike trimer of phage P22 have been identified in vivo and in vitro using native gel electrophoresis in the cold. Aggregation of folding intermediates was suppressed when refolding was initiated and allowed to proceed for a short period at 0 degrees C prior to warming to 20 degrees C. Yields of refolded tailspike trimers exceeding 80% were obtained using this temperature-shift procedure, first described by Xie and Wetlaufer (1996, Protein Sci 5:517-523). We interpret this as due to stabilization of the thermolabile monomeric intermediate at the junction between productive folding and off-pathway aggregation. Partially folded monomers, a newly identified dimer, and the protrimer folding intermediates were populated in the cold. These species were electrophoretically distinguished from the multimeric intermediates populated on the aggregation pathway. The productive protrimer intermediate is disulfide bonded (Robinson AS, King J, 1997, Nat Struct Biol 4:450-455), while the multimeric aggregation intermediates are not disulfide bonded. The partially folded dimer appears to be a precursor to the disulfide-bonded protrimer. The results support a model in which the junctional partially folded monomeric intermediate acquires resistance to aggregation in the cold by folding further to a conformation that is activated for correct recognition and subunit assembly. PMID:9684883

Dynamics of transparent exopolymer particle (TEP) production and aggregation during viral infection of the coccolithophore, Emiliania huxleyi.

PubMed

Nissimov, Jozef I; Vandzura, Rebecca; Johns, Christopher T; Natale, Frank; Haramaty, Liti; Bidle, Kay D

2018-06-19

Emiliania huxleyi produces calcium carbonate (CaCO 3 ) coccoliths and transparent exopolymer particles (TEP), sticky, acidic carbohydrates that facilitate aggregation. E. huxleyi's extensive oceanic blooms are often terminated by coccolithoviruses (EhVs) with the transport of cellular debris and associated particulate organic carbon (POC) to depth being facilitated by TEP-bound "marine snow" aggregates. The dynamics of TEP production and particle aggregation in response to EhV infection are poorly understood. Using flow cytometry, spectrophotometry, and FlowCam visualization of alcian blue (AB)-stained aggregates, we assessed TEP production and the size spectrum of aggregates for E. huxleyi possessing different degrees of calcification and cellular CaCO 3 :POC mass ratios, when challenged with two EhVs (EhV207 and EhV99B1). FlowCam imaging also qualitatively assessed the relative amount of AB-stainable TEP (i.e. blue:red ratio of each particle). We show significant increases in TEP during early phase EhV207-infection (∼24 hours) of calcifying strains and a shift towards large aggregates following EhV99B1-infection. We also observed the formation of large aggregates with low blue:red ratios, suggesting that other exopolymer substances contribute towards aggregation. Our findings show the potential for virus infection and the associated response of their hosts to impact carbon flux dynamics and provide incentive to explore these dynamics in natural populations. This article is protected by copyright. All rights reserved. © 2018 Society for Applied Microbiology and John Wiley & Sons Ltd.

Skin sensitisation quantitative risk assessment (QRA) based on aggregate dermal exposure to methylisothiazolinone in personal care and household cleaning products.

PubMed

Ezendam, J; Bokkers, B G H; Bil, W; Delmaar, J E

2018-02-01

Contact allergy to preservatives is an important public health problem. Ideally, new substances should be evaluated for the risk on skin sensitisation before market entry, for example by using a quantitative risk assessment (QRA) as developed for fragrances. As a proof-of-concept, this QRA was applied to the preservative methylisothiazolinone (MI), a common cause of contact allergy. MI is used in different consumer products, including personal care products (PCPs) and household cleaning products (HCPs). Aggregate exposure to MI in PCPs and HCPs was therefore assessed with the Probabilistic Aggregated Consumer Exposure Model (PACEM). Two exposure scenarios were evaluated: scenario 1 calculated aggregate exposure on actual MI product concentrations before the restricted use in PCPs and scenario 2 calculated aggregate exposure using the restrictions for MI in PCPs. The QRA for MI showed that in scenarios 1 and 2, the proportion of the population at risk for skin sensitisation is 0.7% and 0.5%, respectively. The restricted use of MI in PCPs does not seem very effective in lowering the risk on skin sensitization. To conclude, it is important to consider aggregate exposure from the most important consumer products into consideration in the risk assessment. Copyright © 2018 Elsevier Ltd. All rights reserved.

75 FR 39612 - Allocation of Second Additional Fiscal Year (FY) 2010 In-Quota Volume for Raw Cane Sugar

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-09

...) 2010 In-Quota Volume for Raw Cane Sugar AGENCY: Office of the United States Trade Representative... the tariff-rate quota (TRQ) for imported raw cane sugar. DATES: Effective Date: July 9, 2010... Harmonized Tariff Schedule of the United States (HTS), the United States maintains TRQs for imports of raw...

Distinguishing values from science in decision making: Setting harvest quotas for mountain lions in Montana

USGS Publications Warehouse

Mitchell, Michael S.; Cooley, Hilary; Gude, Justin A.; Kolbe, Jay; Nowak, J. Joshua; Proffitt, Kelly M.; Sells, Sarah N.; Thompson, Mike

2018-01-01

The relative roles of science and human values can be difficult to distinguish when informal processes are used to make complex and contentious decisions in wildlife management. Structured Decision Making (SDM) offers a formal process for making such decisions, where scientific results and concepts can be disentangled from the values of differing stakeholders. We used SDM to formally integrate science and human values for a citizen working group of ungulate hunting advocates, lion hunting advocates, and outfitters convened to address the contentious allocation of harvest quotas for mountain lions (Puma concolor) in west‐central Montana, USA, during 2014. A science team consisting of mountain lion biologists and population ecologists convened to support the working group. The science team used integrated population models that incorporated 4 estimates of mountain lion density to estimate population trajectories for 5 alternative harvest quotas developed by the working group. Results of the modeling predicted that effects of each harvest quota were consistent across the 4 density estimates; harvest quotas affected predicted population trajectories for 5 years after implementation but differences were not strong. Based on these results, the focus of the working group changed to differences in values among stakeholders that were the true impediment to allocating harvest quotas. By distinguishing roles of science and human values in this process, the working group was able to collaboratively recommend a compromise solution. This solution differed little from the status quo that had been the focus of debate, but the SDM process produced understanding and buy‐in among stakeholders involved, reducing disagreements, misunderstanding, and unproductive arguments founded on informal application of scientific data and concepts. Whereas investments involved in conducting SDM may be unnecessary for many decisions in wildlife management, the investment may be beneficial for

Optimization the composition of sand-lime products modified of diabase aggregate

NASA Astrophysics Data System (ADS)

Komisarczyk, K.; Stępień, A.

2017-10-01

The problem of optimizing the composition of building materials is currently of great importance due to the increasing competitiveness and technological development in the construction industry. This phenomenon also applies to catalog sand-lime. The respective arrangement of individual components or their equivalents, and linking them with the main parameters of the composition of the mixture, i.e. The lime/sand/water should lead to the intended purpose. The introduction of sand-lime diabase aggregate is concluded with a positive effect of final products. The paper presents the results of optimization with the addition of diabase aggregate. The constant value was the amount of water, variable - the mass of the dry ingredients. The program of experimental studies was taken for 6 series of silicates made in industrial conditions. Final samples were tested for mechanical and physico-chemical expanding the analysis of the mercury intrusion porosimetry, SEM and XRD. The results show that, depending on the aggregate’s contribution, exhibit differences. The sample in an amount of 10% diabase aggregate the compressive strength was higher than in the case of reference sample, while modified samples absorbed less water.

77 FR 51751 - Assessment of Fees for Dairy Import Licenses for the 2013 Tariff-Rate Import Quota Year

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-27

... Licenses for the 2013 Tariff- Rate Import Quota Year AGENCY: Foreign Agricultural Service, USDA. ACTION: Notice. SUMMARY: This notice announces a fee of $170 to be charged for the 2013 tariff- [[Page 51752... authorizing the importation of certain dairy articles, which are subject to tariff-rate quotas set forth in...

50 CFR 648.120 - Catch quotas and other restrictions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... this section will not be exceeded: (1) Research quota set from a range of 0 to 3 percent of the maximum... periods, and deducting the discard estimates for each period. (3) Possession limits for the Winter I and... (17.8 cm) TL to 10 inches (25.4 cm) TL. (9) Recreational season. (10) Restrictions on gear. (11...

50 CFR 622.15 - Wreckfish individual transferable quota (ITQ) system.

Code of Federal Regulations, 2010 CFR

2010-10-01

... shares. (1) In accordance with the procedure specified in the Fishery Management Plan for the Snapper-Grouper Fishery of the South Atlantic Region, percentage shares of the quota for wreckfish have been... (ITQ) system. 622.15 Section 622.15 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT...

77 FR 57180 - Fiscal Year 2013 Tariff-rate Quota Allocations for Raw Cane Sugar, Refined and Specialty Sugar...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-17

... OFFICE OF THE TRADE REPRESENTATIVE Fiscal Year 2013 Tariff-rate Quota Allocations for Raw Cane... quantity of the tariff-rate quotas for imported raw cane sugar, refined and specialty sugar, and sugar... imports of raw cane sugar and refined sugar. Pursuant to Additional U.S. Note 8 to Chapter 17 of the HTS...

78 FR 46565 - Assessment of Fees for Dairy Import Licenses for the 2014 Tariff-Rate Import Quota Year

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-01

... Service Assessment of Fees for Dairy Import Licenses for the 2014 Tariff- Rate Import Quota Year AGENCY... charged for the 2014 tariff-rate quota (TRQ) year for each license issued to a person or firm by the... 2014 calendar year. Notice: The total cost to the Department of Agriculture of administering the...

Process for producing an aggregate suitable for inclusion into a radiation shielding product

DOEpatents

Lessing, Paul A.; Kong, Peter C.

2000-01-01

The present invention is directed to methods for converting depleted uranium hexafluoride to a stable depleted uranium silicide in a one-step reaction. Uranium silicide provides a stable aggregate material that can be added to concrete to increase the density of the concrete and, consequently, shield gamma radiation. As used herein, the term "uranium silicide" is defined as a compound generically having the formula U.sub.x Si.sub.y, wherein the x represents the molecules of uranium and the y represent the molecules of silicon. In accordance with the present invention, uranium hexafluoride is converted to a uranium silicide by contacting the uranium hexafluoride with a silicon-containing material at a temperature in a range between about 1450.degree. C. and about 1750.degree. C. The stable depleted uranium silicide is included as an aggregate in a radiation shielding product, such as a concrete product.

Self-Healing Capacity of Asphalt Mixtures Including By-Products Both as Aggregates and Heating Inductors.

PubMed

Vila-Cortavitarte, Marta; Jato-Espino, Daniel; Castro-Fresno, Daniel; Calzada-Pérez, Miguel Á

2018-05-15

Major advances have been achieved in the field of self-healing by magnetic induction in which the addition of metallic particles into asphalt mixtures enables repairing their own cracks. This technology has already been proven to increase the life expectancy of roads. Nevertheless, its higher costs in comparison with conventional maintenance caused by the price of virgin metallic particles still makes it unattractive for investment. This research aimed at making this process economically accessible as well as environmentally efficient. To this end, an intense search for suitable industrial by-products to substitute both the virgin metal particles and the natural aggregates forming asphalt mixtures was conducted. The set of by-products used included sand blasting wastes, stainless shot wastes, and polished wastes as metallic particles and other inert by-products as aggregates. The results demonstrated that the by-products were adequately heated, which leads to satisfactory healing ratios in comparison with the reference mixture.

Self-Healing Capacity of Asphalt Mixtures Including By-Products Both as Aggregates and Heating Inductors

PubMed Central

Castro-Fresno, Daniel; Calzada-Pérez, Miguel Á.

2018-01-01

Major advances have been achieved in the field of self-healing by magnetic induction in which the addition of metallic particles into asphalt mixtures enables repairing their own cracks. This technology has already been proven to increase the life expectancy of roads. Nevertheless, its higher costs in comparison with conventional maintenance caused by the price of virgin metallic particles still makes it unattractive for investment. This research aimed at making this process economically accessible as well as environmentally efficient. To this end, an intense search for suitable industrial by-products to substitute both the virgin metal particles and the natural aggregates forming asphalt mixtures was conducted. The set of by-products used included sand blasting wastes, stainless shot wastes, and polished wastes as metallic particles and other inert by-products as aggregates. The results demonstrated that the by-products were adequately heated, which leads to satisfactory healing ratios in comparison with the reference mixture. PMID:29762533

A deterministic aggregate production planning model considering quality of products

NASA Astrophysics Data System (ADS)

Madadi, Najmeh; Yew Wong, Kuan

2013-06-01

Aggregate Production Planning (APP) is a medium-term planning which is concerned with the lowest-cost method of production planning to meet customers' requirements and to satisfy fluctuating demand over a planning time horizon. APP problem has been studied widely since it was introduced and formulated in 1950s. However, in several conducted studies in the APP area, most of the researchers have concentrated on some common objectives such as minimization of cost, fluctuation in the number of workers, and inventory level. Specifically, maintaining quality at the desirable level as an objective while minimizing cost has not been considered in previous studies. In this study, an attempt has been made to develop a multi-objective mixed integer linear programming model that serves those companies aiming to incur the minimum level of operational cost while maintaining quality at an acceptable level. In order to obtain the solution to the multi-objective model, the Fuzzy Goal Programming approach and max-min operator of Bellman-Zadeh were applied to the model. At the final step, IBM ILOG CPLEX Optimization Studio software was used to obtain the experimental results based on the data collected from an automotive parts manufacturing company. The results show that incorporating quality in the model imposes some costs, however a trade-off should be done between the cost resulting from producing products with higher quality and the cost that the firm may incur due to customer dissatisfaction and sale losses.

75 FR 35838 - Controlled Substances: Proposed Revised Aggregate Production Quotas for 2010

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-23

...,000,000 g Amphetamine (for conversion) 6,500,000 g 6,500,000 g Cocaine 247,000 g 247,000 g Codeine... Fairness Act of 1996 (Congressional Review Act). This action will not result in an annual effect on the economy of $100,000,000 or more; a major increase in costs or prices; or significant adverse effects on...

7 CFR 1463.106 - Base quota levels for eligible tobacco producers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Base quota levels for eligible tobacco producers. 1463.106 Section 1463.106 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS 2005-2014...

Effect of carbon sources on the aggregation of photo fermentative bacteria induced by L-cysteine for enhancing hydrogen production.

PubMed

Xie, Guo-Jun; Liu, Bing-Feng; Ding, Jie; Wang, Qilin; Ma, Chao; Zhou, Xu; Ren, Nan-Qi

2016-12-01

Poor flocculation of photo fermentative bacteria resulting in continuous biomass washout from photobioreactor is a critical challenge to achieve rapid and stable hydrogen production. In this work, the aggregation of Rhodopseudomonas faecalis RLD-53 was successfully developed in a photobioreactor and the effects of different carbon sources on hydrogen production and aggregation ability were investigated. Extracellular polymeric substances (EPS) production by R. faecalis RLD-53 cultivated using different carbon sources were stimulated by addition of L-cysteine. The absolute ζ potentials of R. faecalis RLD-53 were considerably decreased with addition of L-cysteine, and aggregation barriers based on DLVO dropped to 15-43 % of that in control groups. Thus, R. faecalis RLD-53 flocculated effectively, and aggregation abilities of strain RLD-53 cultivated with acetate, propionate, lactate and malate reached 29.35, 32.34, 26.07 and 24.86 %, respectively. In the continuous test, hydrogen-producing activity was also promoted and reached 2.45 mol H 2 /mol lactate, 3.87 mol H 2 /mol propionate and 5.10 mol H 2 /mol malate, respectively. Therefore, the aggregation of R. faecalis RLD-53 induced by L-cysteine is independent on the substrate types, which ensures the wide application of this technology to enhance hydrogen recovery from wastewater dominated by different organic substrates.

19 CFR 132.12 - Procedure on opening of potentially filled quotas.

Code of Federal Regulations, 2010 CFR

2010-04-01

... consumption, with estimated duties attached, shall not be presented before 12 noon Eastern Standard Time in all time zones. However, an entry summary for consumption, or withdrawal for consumption, for... exact moment of the opening of the quota in all time zones. All importers prepared to present entry...

Azaphilones inhibit tau aggregation and dissolve tau aggregates in vitro.

PubMed

Paranjape, Smita R; Riley, Andrew P; Somoza, Amber D; Oakley, C Elizabeth; Wang, Clay C C; Prisinzano, Thomas E; Oakley, Berl R; Gamblin, T Chris

2015-05-20

The aggregation of the microtubule-associated protein tau is a seminal event in many neurodegenerative diseases, including Alzheimer's disease. The inhibition or reversal of tau aggregation is therefore a potential therapeutic strategy for these diseases. Fungal natural products have proven to be a rich source of useful compounds having wide varieties of biological activities. We have previously screened Aspergillus nidulans secondary metabolites for their ability to inhibit tau aggregation in vitro using an arachidonic acid polymerization protocol. One aggregation inhibitor identified was asperbenzaldehyde, an intermediate in azaphilone biosynthesis. We therefore tested 11 azaphilone derivatives to determine their tau assembly inhibition properties in vitro. All compounds tested inhibited tau filament assembly to some extent, and four of the 11 compounds had the advantageous property of disassembling preformed tau aggregates in a dose-dependent fashion. The addition of these compounds to the tau aggregates reduced both the total length and number of tau polymers. The most potent compounds were tested in in vitro reactions to determine whether they interfere with tau's normal function of stabilizing microtubules (MTs). We found that they did not completely inhibit MT assembly in the presence of tau. These derivatives are very promising lead compounds for tau aggregation inhibitors and, more excitingly, for compounds that can disassemble pre-existing tau filaments. They also represent a new class of anti-tau aggregation compounds with a novel structural scaffold.

Monitoring of conditions inside gas aggregation cluster source during production of Ti/TiOx nanoparticles

NASA Astrophysics Data System (ADS)

Kousal, J.; Kolpaková, A.; Shelemin, A.; Kudrna, P.; Tichý, M.; Kylián, O.; Hanuš, J.; Choukourov, A.; Biederman, H.

2017-10-01

Gas aggregation sources are nowadays rather widely used in the research community for producing nanoparticles. However, the direct diagnostics of conditions inside the source are relatively scarce. In this work, we focused on monitoring the plasma parameters and the composition of the gas during the production of the TiOx nanoparticles. We studied the role of oxygen in the aggregation process and the influence of the presence of the particles on the plasma. The construction of the source allowed us to make a 2D map of the plasma parameters inside the source.

The Optimum Production Method for Quality Improvement of Recycled Aggregates Using Sulfuric Acid and the Abrasion Method.

PubMed

Kim, Haseog; Park, Sangki; Kim, Hayong

2016-07-29

There has been increased deconstruction and demolition of reinforced concrete structures due to the aging of the structures and redevelopment of urban areas resulting in the generation of massive amounts of construction. The production volume of waste concrete is projected to increase rapidly over 100 million tons by 2020. However, due to the high cement paste content, recycled aggregates have low density and high absorption ratio. They are mostly used for land reclamation purposes with low added value instead of multiple approaches. This study was performed to determine an effective method to remove cement paste from recycled aggregates by using the abrasion and substituting the process water with acidic water. The aim of this study is to analyze the quality of the recycled fine aggregates produced by a complex method and investigate the optimum manufacturing conditions for recycled fine aggregates based on the design of experiment. The experimental parameters considered were water ratio, coarse aggregate ratio, and abrasion time and, as a result of the experiment, data concerning the properties of recycled sand were obtained. It was found that high-quality recycled fine aggregates can be obtained with 8.57 min of abrasion-crusher time and a recycled coarse aggregate ratio of over 1.5.

46 CFR 356.55 - Review of compliance with harvesting and processing quotas.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Review of compliance with harvesting and processing quotas. 356.55 Section 356.55 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION MISCELLANEOUS REQUIREMENTS FOR VESSELS OF 100 FEET OR GREATER IN REGISTERED LENGTH TO OBTAIN A FISHERY...

46 CFR 356.55 - Review of compliance with harvesting and processing quotas.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 8 2011-10-01 2011-10-01 false Review of compliance with harvesting and processing quotas. 356.55 Section 356.55 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION MISCELLANEOUS REQUIREMENTS FOR VESSELS OF 100 FEET OR GREATER IN REGISTERED LENGTH TO OBTAIN A FISHERY...

The combination of simulation and response methodology and its application in an aggregate production plan

NASA Astrophysics Data System (ADS)

Chen, Zhiming; Feng, Yuncheng

1988-08-01

This paper describes an algorithmic structure for combining simulation and optimization techniques both in theory and practice. Response surface methodology is used to optimize the decision variables in the simulation environment. A simulation-optimization software has been developed and successfully implemented, and its application to an aggregate production planning simulation-optimization model is reported. The model's objective is to minimize the production cost and to generate an optimal production plan and inventory control strategy for an aircraft factory.

Photo-fermentative bacteria aggregation triggered by L-cysteine during hydrogen production

PubMed Central

2013-01-01

Background Hydrogen recovered from organic wastes and solar energy by photo-fermentative bacteria (PFB) has been suggested as a promising bioenergy strategy. However, the use of PFB for hydrogen production generally suffers from a serious biomass washout from photobioreactor, due to poor flocculation of PFB. In the continuous operation, PFB cells cannot be efficiently separated from supernatant and rush out with effluent from reactor continuously, which increased the effluent turbidity, meanwhile led to increases in pollutants. Moreover, to replenish the biomass washout, substrate was continuously utilized for cell growth rather than hydrogen production. Consequently, the poor flocculability not only deteriorated the effluent quality, but also decreased the potential yield of hydrogen from substrate. Therefore, enhancing the flocculability of PFB is urgent necessary to further develop photo-fermentative process. Results Here, we demonstrated that L-cysteine could improve hydrogen production of Rhodopseudomonas faecalis RLD-53, and more importantly, simultaneously trigger remarkable aggregation of PFB. Experiments showed that L-cysteine greatly promoted the production of extracellular polymeric substances, especially secretion of protein containing more disulfide bonds, and help for enhancement stability of floc of PFB. Through formation of disulfide bonds, L-cysteine not only promoted production of EPS, in particular the secretion of protein, but also stabilized the final confirmation of protein in EPS. In addition, the cell surface elements and functional groups, especially surface charged groups, have also been changed by L-cysteine. Consequently, absolute zeta potential reached a minimum value at 1.0 g/l of L-cysteine, which obviously decreased electrostatic repulsion interaction energy based on DLVO theory. Total interaction energy barrier decreased from 389.77 KT at 0.0 g/l of L-cysteine to 127.21 kT at 1.0 g/l. Conclusions Thus, the strain RLD-53 overcame the

Recycling of quarry waste as part of sustainable aggregate production: Norwegian and Italian point of view

NASA Astrophysics Data System (ADS)

Antonella Dino, Giovanna; Willy Danielsen, Svein; Chiappino, Claudia; Primavori, Piero; Engelsen, Christian John

2016-04-01

Resource preservation is one of the main challenges in Europe, together with waste management and recycling; recently several researchers are interested in the recovering of critical raw materials and secondary raw materials from landfill. Aggregate supply, even if it is not "critical" sensus stricto (s.s.), is one of the European priorities (low value but high volume needs). On the other side, the management of quarry waste , mainly from dimension stones, but also as fines from aggregate crushing, is still a matter of concern. Such materials are managed in different ways both locally and nationwide, and often they are landfilled, because of an unclear legislation and a general lack of data. Most of time the local authorities adopt the maximum precaution principle or the enterprises find it little profitable to recover them, so that the sustainable recycling of such material is not valued. Several studies have shown, depending on the material specific characteristics, the viability of recycling quarry waste into new raw materials used in glass and ceramic industries, precast concrete production, infrastructures etc. (Loudes et al. 2012, Dino&Marian 2015, Bozzola et al 2012, Dino et al. 2012, etc.). Thus, aggregate production may be one of the profitable ways to use quarry waste and is falling under the priority of EU (aggregate supply). Positive economic and environmental effects are likely to be achieved by systematic recycling of quarry waste planned by industries (industrial planning) and public authorities (national and local planning of aggregate exploitation). Today, the recycling level varies to a great extent and systematic recovery is not common among European Countries. In Italy and Norway no significant incentives on recycling or systematic approaches for local aggregate exploitation exist. The environmental consequences can be overexploitation of the natural resources, land take for the landfills, environmental contamination and landscape alteration by

78 FR 54399 - Fisheries of the Northeastern United States; Bluefish Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-04

.... 130104009-3416-02] RIN 0648-XC815 Fisheries of the Northeastern United States; Bluefish Fishery; Quota Transfer AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric Administration...: Carly Bari, Fishery Management Specialist, 978-281-9224. SUPPLEMENTARY INFORMATION: Regulations...

77 FR 58969 - Fisheries of the Northeastern United States; Bluefish Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-25

.... 120201086-2418-02] RIN 0648-XC235 Fisheries of the Northeastern United States; Bluefish Fishery; Quota Transfer AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric Administration...: Carly Bari, Fishery Management Specialist, 978-281-9224. SUPPLEMENTARY INFORMATION: Regulations...

21 CFR 1303.22 - Procedure for applying for individual manufacturing quotas.

Code of Federal Regulations, 2011 CFR

2011-04-01

... in Schedule I or II and who desires to manufacture a quantity of such class shall apply on DEA Form 189 for a manufacturing quota for such quantity of such class. Copies of DEA Form 189 may be obtained... Administration. See the Table of DEA Mailing Addresses in § 1321.01 of this chapter for the current mailing...

Construction aggregates

USGS Publications Warehouse

Nelson, T.I.; Bolen, W.P.

2007-01-01

Construction aggregates, primarily stone, sand and gravel, are recovered from widespread naturally occurring mineral deposits and processed for use primarily in the construction industry. They are mined, crushed, sorted by size and sold loose or combined with portland cement or asphaltic cement to make concrete products to build roads, houses, buildings, and other structures. Much smaller quantities are used in agriculture, cement manufacture, chemical and metallurgical processes, glass production and many other products.

The Nation's top 25 construction aggregates producers

USGS Publications Warehouse

Willett, Jason Christopher

2013-01-01

U.S. production of construction aggregates in 2011 was 2.17 billion short tons, valued at $17.2 billion, free on board (f.o.b.) at plant. Construction aggregates production decreased by 37 percent, and the associated value decreased by 25 percent, compared with the record highs reported in 2006. In 2011, construction aggregates production increased for the first time since 2006, owing to a very slight increase in the production of both construction sand and gravel and crushed stone. The average unit value, which is the f.o.b. at plant price of a ton of material, increased slightly, but is still less than the average unit value of two years prior.

76 FR 74009 - Fisheries of the Northeastern United States; Bluefish Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-30

.... 101228634-1149-02] RIN 0648-XA825 Fisheries of the Northeastern United States; Bluefish Fishery; Quota Transfer AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric Administration..., 2011, through December 31, 2011. FOR FURTHER INFORMATION CONTACT: Carly Bari, Fishery Management...

Properties of Concrete with Tire Derived Aggregate Partially Replacing Coarse Aggregates.

PubMed

Siringi, Gideon; Abolmaali, Ali; Aswath, Pranesh B

2015-01-01

Tire derived aggregate (TDA) has been proposed as a possible lightweight replacement for mineral aggregate in concrete. The role played by the amount of TDA replacing coarse aggregate as well as different treatment and additives in concrete on its properties is examined. Conventional concrete (without TDA) and concrete containing TDA are compared by examining their compressive strength based on ASTM C39, workability based on ASTM C143, splitting tensile strength based on ASTM C496, modulus of rupture (flexural strength) based on ASTM C78, and bond stress based on ASTM C234. Results indicate that while replacement of coarse aggregates with TDA results in reduction in strength, it may be mitigated with addition of silica fume to obtain the desired strength. The greatest benefit of using TDA is in the development of a higher ductile product while utilizing recycled TDA.

Comparative environmental assessment of natural and recycled aggregate concrete.

PubMed

Marinković, S; Radonjanin, V; Malešev, M; Ignjatović, I

2010-11-01

Constant and rapid increase in construction and demolition (C&D) waste generation and consumption of natural aggregate for concrete production became one of the biggest environmental problems in the construction industry. Recycling of C&D waste represents one way to convert a waste product into a resource but the environment benefits through energy consumption, emissions and fallouts reductions are not certain. The main purpose of this study is to determine the potentials of recycled aggregate concrete (concrete made with recycled concrete aggregate) for structural applications and to compare the environmental impact of the production of two types of ready-mixed concrete: natural aggregate concrete (NAC) made entirely with river aggregate and recycled aggregate concrete (RAC) made with natural fine and recycled coarse aggregate. Based on the analysis of up-to-date experimental evidence, including own tests results, it is concluded that utilization of RAC for low-to-middle strength structural concrete and non-aggressive exposure conditions is technically feasible. The Life Cycle Assessment (LCA) is performed for raw material extraction and material production part of the concrete life cycle including transport. Assessment is based on local LCI data and on typical conditions in Serbia. Results of this specific case study show that impacts of aggregate and cement production phases are slightly larger for RAC than for NAC but the total environmental impacts depend on the natural and recycled aggregates transport distances and on transport types. Limit natural aggregate transport distances above which the environmental impacts of RAC can be equal or even lower than the impacts of NAC are calculated for the specific case study. Copyright © 2010 Elsevier Ltd. All rights reserved.

77 FR 19175 - Atlantic Highly Migratory Species; 2012 Atlantic Bluefin Tuna Quota Specifications

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-30

...-XA920 Atlantic Highly Migratory Species; 2012 Atlantic Bluefin Tuna Quota Specifications AGENCY... INFORMATION: Atlantic bluefin tuna, bigeye tuna, albacore tuna, yellowfin tuna, and skipjack tuna (hereafter referred to as ``Atlantic tunas'') are managed under the dual authority of the Magnuson-Stevens Fishery...

77 FR 76424 - Fisheries of the Northeastern United States; Bluefish Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-28

.... 120201086-2418-02] RIN 0648-XC394 Fisheries of the Northeastern United States; Bluefish Fishery; Quota Transfer AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric Administration...: Effective December 21, 2012, through December 31, 2012. FOR FURTHER INFORMATION CONTACT: Carly Bari, Fishery...

78 FR 64182 - Fisheries of the Northeastern United States; Bluefish Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-28

.... 130104009-3416-02] RIN 0648-XC921 Fisheries of the Northeastern United States; Bluefish Fishery; Quota Transfer AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric Administration...: Effective October 25, 2013, through December 31, 2013. FOR FURTHER INFORMATION CONTACT: Carly Bari, Fishery...

A comparative study on carbon footprint of rice production between household and aggregated farms from Jiangxi, China.

PubMed

Yan, Ming; Luo, Ting; Bian, Rongjun; Cheng, Kun; Pan, Genxing; Rees, Robert

2015-06-01

Quantifying the carbon footprint (CF) for crop production can help identify key options to mitigate greenhouse gas (GHG) emissions in agriculture. In the present study, both household and aggregated farm scales were surveyed to obtain the data of rice production and farming management practices in a typical rice cultivation area of Northern Jiangxi, China. The CFs of the different rice systems including early rice, late rice, and single rice under household and aggregated farm scale were calculated. In general, early rice had the lower CF in terms of land use and grain production being 4.54 ± 0.44 t CO2-eq./ha and 0.62 ± 0.1 t CO2-eq./t grain than single rice (6.84 ± 0.79 t CO2-eq./ha and 0.80 ± 0.13 t CO2-eq./t grain) and late rice (8.72 ± 0.54 t CO2-eq./ha and 1.1 ± 0.17 t CO2-eq./t grain). The emissions from nitrogen fertilizer use accounted for 33 % of the total CF on average and the direct CH4 emissions for 57 %. The results indicated that the CF of double rice cropping under aggregated farm being 0.86 ± 0.11 t CO2-eq./t grain was lower by 25 % than that being 1.14 ± 0.25 t CO2-eq./t grain under household farm, mainly due to high nitrogen use efficiency and low methane emissions. Therefore, developing the aggregated farm scale with efficient use of agro-chemicals and farming operation for greater profitability could offer a strategy for reducing GHG emissions in China's agriculture.

[Import and export of licorice and its products in China].

PubMed

Ma, Shuai; Wang, Nuo; Yang, Guang; Que, Ling

2017-06-01

Licorice is an important harmonic drug which has been widely used in traditional Chinese medicine since ancient times. However, with the increasing demand of industrial production, the licorice resources in our country have been reduced rapidly and we have to import licorice resources from Kazakhstan and Uzbekistan consequently. In order to find out the trade flow of licorice resources and evaluate the status of Chinese licorice in the world trade, the trade situation of licorice and its products from 2011 to 2015 May in Chinese customs was investigated and analyzed in this paper. The import and export volumes of licorice were declining; the import and export volumes of licorice were relatively concentrated in international trade, with greater risks of trade; and export quota management was not well executed. As one of the strategic resources of medicine, licorice resources must be based on domestic development, and we should adjust the export quota management from passive quota to active quota management and improve the intrinsic value of licorice resources to establish the international market position of our licorice and control the pricing power in international market. Copyright© by the Chinese Pharmaceutical Association.

Investigation of Physico-Chemical Properties of Sand-Lime Products Modified of Diabase Aggregate and Chalcedonite Meal

NASA Astrophysics Data System (ADS)

Dachowski, Ryszard; Komisarczyk, Katarzyna

2017-10-01

In the era of rapid development in the construction industry, particular attention is focused on harmless and natural materials. Some of the best materials for building masonry walls are sand-lime products. Silicates are obtained from a mixture of quartz, sand and a small amount of water. They emerge as a result of the hydrothermal treatment conducted under high pressure and at a temperature of app. 203 °C. Silicates were modified of different kinds of aggregates, glass or plastics, and the content of dry ingredients was changed because of this fact. The paper describes the studies where the combination of diabase aggregate and chalcedonite meal was used. Microstructure of the products was analyzed with the use of mercury intrusion porosimetry, SEM and XRD methods. Variable content of chalcedonite meal changes the internal structure and the physico-chemical properties.

Properties of Concrete with Tire Derived Aggregate Partially Replacing Coarse Aggregates

PubMed Central

Siringi, Gideon; Abolmaali, Ali; Aswath, Pranesh B.

2015-01-01

Tire derived aggregate (TDA) has been proposed as a possible lightweight replacement for mineral aggregate in concrete. The role played by the amount of TDA replacing coarse aggregate as well as different treatment and additives in concrete on its properties is examined. Conventional concrete (without TDA) and concrete containing TDA are compared by examining their compressive strength based on ASTM C39, workability based on ASTM C143, splitting tensile strength based on ASTM C496, modulus of rupture (flexural strength) based on ASTM C78, and bond stress based on ASTM C234. Results indicate that while replacement of coarse aggregates with TDA results in reduction in strength, it may be mitigated with addition of silica fume to obtain the desired strength. The greatest benefit of using TDA is in the development of a higher ductile product while utilizing recycled TDA. PMID:26161440

76 FR 19276 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-07

.... 101029427-0609-02] RIN 0648-XA338 Fisheries of the Northeastern United States; Summer Flounder Fishery... of North Carolina is transferring a portion of its 2011 commercial summer flounder quota to the Commonwealth of [[Page 19277

The nation’s top 25 construction aggregates producers

USGS Publications Warehouse

Willett, Jason C.

2014-01-01

U.S. production of construction aggregates in 2012 was 2.18 billion short tons valued at $17.6 billion, free on board (f.o.b.) at plant. In 2012, construction aggregates production remained virtually unchanged from the levels of the last two years because of a very slight increase compared with that of 2011 in the production of both construction sand and gravel and crushed stone. The average unit value, which is the f.o.b. at the plant price of a metric ton of material, increased slightly. Construction aggregates production was 36 percent less than and the associated value was 23 percent less than the record highs reported in 2006.

Hsp90 activator Aha1 drives production of pathological tau aggregates

PubMed Central

Shelton, Lindsey B.; Baker, Jeremy D.; Zheng, Dali; Sullivan, Leia E.; Solanki, Parth K.; Webster, Jack M.; Sun, Zheying; Sabbagh, Jonathan J.; Nordhues, Bryce A.; Koren, John; Ghosh, Suman; Blagg, Brian S. J.; Dickey, Chad A.

2017-01-01

The microtubule-associated protein tau (MAPT, tau) forms neurotoxic aggregates that promote cognitive deficits in tauopathies, the most common of which is Alzheimer’s disease (AD). The 90-kDa heat shock protein (Hsp90) chaperone system affects the accumulation of these toxic tau species, which can be modulated with Hsp90 inhibitors. However, many Hsp90 inhibitors are not blood–brain barrier-permeable, and several present associated toxicities. Here, we find that the cochaperone, activator of Hsp90 ATPase homolog 1 (Aha1), dramatically increased the production of aggregated tau. Treatment with an Aha1 inhibitor, KU-177, dramatically reduced the accumulation of insoluble tau. Aha1 colocalized with tau pathology in human brain tissue, and this association positively correlated with AD progression. Aha1 overexpression in the rTg4510 tau transgenic mouse model promoted insoluble and oligomeric tau accumulation leading to a physiological deficit in cognitive function. Overall, these data demonstrate that Aha1 contributes to tau fibril formation and neurotoxicity through Hsp90. This suggests that therapeutics targeting Aha1 may reduce toxic tau oligomers and slow or prevent neurodegenerative disease progression. PMID:28827321

Characterizing harmful advanced glycation end-products (AGEs) and ribosylated aggregates of yellow mustard seed phytocystatin: Effects of different monosaccharides

NASA Astrophysics Data System (ADS)

Ahmed, Azaj; Shamsi, Anas; Bano, Bilqees

2017-01-01

Advanced glycation end products (AGEs) are at the core of variety of diseases ranging from diabetes to renal failure and hence gaining wide consideration. This study was aimed at characterizing the AGEs of phytocystatin isolated from mustard seeds (YMP) when incubated with different monosaccharides (glucose, ribose and mannose) using fluorescence, ultraviolet, circular dichroism (CD) spectroscopy and microscopy. Ribose was found to be the most potent glycating agent as evident by AGEs specific fluorescence and absorbance. YMP exists as a molten globule like structure on day 24 as depicted by high ANS fluorescence and altered intrinsic fluorescence. Glycated YMP as AGEs and ribose induced aggregates were observed at day 28 and 32 respectively. In our study we have also examined the anti-aggregative potential of polyphenol, resveratrol. Our results suggested the anti-aggregative behavior of resveratrol as it prevented the in vitro aggregation of YMP, although further studies are required to decode the mechanism by which resveratrol prevents the aggregation.

Diatom-associated bacteria are required for aggregation of Thalassiosira weissflogii

PubMed Central

Gärdes, Astrid; Iversen, Morten H; Grossart, Hans-Peter; Passow, Uta; Ullrich, Matthias S

2011-01-01

Aggregation of algae, mainly diatoms, is an important process in marine systems leading to the settling of particulate organic carbon predominantly in the form of marine snow. Exudation products of phytoplankton form transparent exopolymer particles (TEP), which acts as the glue for particle aggregation. Heterotrophic bacteria interacting with phytoplankton may influence TEP formation and phytoplankton aggregation. This bacterial impact has not been explored in detail. We hypothesized that bacteria attaching to Thalassiosira weissflogii might interact in a yet-to-be determined manner, which could impact TEP formation and aggregate abundance. The role of individual T. weissflogii-attaching and free-living new bacterial isolates for TEP production and diatom aggregation was investigated in vitro. T. weissflogii did not aggregate in axenic culture, and striking differences in aggregation dynamics and TEP abundance were observed when diatom cultures were inoculated with either diatom-attaching or free-living bacteria. The data indicated that free-living bacteria might not influence aggregation whereas bacteria attaching to diatom cells may increase aggregate formation. Interestingly, photosynthetically inactivated T. weissflogii cells did not aggregate regardless of the presence of bacteria. Comparison of aggregate formation, TEP production, aggregate sinking velocity and solid hydrated density revealed remarkable differences. Both, photosynthetically active T. weissflogii and specific diatom-attaching bacteria were required for aggregation. It was concluded that interactions between heterotrophic bacteria and diatoms increased aggregate formation and particle sinking and thus may enhance the efficiency of the biological pump. PMID:20827289

75 FR 33731 - Atlantic Highly Migratory Species; 2010 Atlantic Bluefin Tuna Quota Specifications

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-15

... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration 50 CFR Part 635 [Docket No. 100317152-0176-01] RIN 0648-AY77 Atlantic Highly Migratory Species; 2010 Atlantic Bluefin Tuna Quota Specifications Correction In rule document 2010-13207 beginning on page 30732 in the issue of Wednesday, June 2...

77 FR 16209 - Proposed Information Collection; Comment Request; Tilefish Individual Fishing Quota Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-20

... Northeastern U.S. EEZ. II. Method of Collection The IFQ Allocation permit application, IFQ ownership cap form... before May 21, 2012. ADDRESSES: Direct all written comments to Jennifer Jessup, Departmental Paperwork... applications to ensure that IFQ allocation owners are provided a statement of their annual catch quota, and for...

77 FR 16210 - Proposed Information Collection; Comment Request; Tilefish Individual Fishing Quota Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-20

... Northeastern U.S. EEZ. II. Method of Collection The IFQ Allocation permit application, IFQ ownership cap form... before May 21, 2012. ADDRESSES: Direct all written comments to Jennifer Jessup, Departmental Paperwork... applications to ensure that IFQ allocation owners are provided a statement of their annual catch quota, and for...

78 FR 30865 - Proposed Information Collection; Comment Request; Tilefish Individual Fishing Quota Program

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-23

... Northeastern U.S. EEZ. II. Method of Collection The IFQ Allocation permit application, IFQ holder cap form, and... before July 22, 2013. ADDRESSES: Direct all written comments to Jennifer Jessup, Departmental Paperwork... applications to ensure that IFQ allocation holders are provided a statement of their annual catch quota, and...

Effect of mineral trioxide aggregate on cytokine production by peritoneal macrophages.

PubMed

Rezende, T M B; Vargas, D L; Cardoso, F P; Sobrinho, A P R; Vieira, L Q

2005-12-01

To test the effect of two commercial brands of grey mineral trioxide aggregate (ProRoot and MTA-Angelus) on cytokine production by M1 and M2 inflammatory macrophages. M1 (from C57BL/6 mice) and M2 peritoneal inflammatory macrophages (from C57BL/6 IL12p40-/- mice) were obtained and cultured in vitro in the presence of MTA. The cellular viability and the production of tumour necrosis factor-alpha, interleukin (IL)-12 and IL-10 in response to stimulation with interferon-gamma and Fusobacterium nucleatum or Peptostreptococcus anaerobius were evaluated. Data were analysed by Mann-Whitney, Kruskal-Wallis and anova tests. The cements did not interfere with cellular viability or with cytokine production by either type of macrophage. However, M2 macrophages produced higher levels of IL-10 when stimulated with F. nucleatum than M1 macrophages (P < 0.05). The brands of MTA evaluated did not interfere in the cytokine response by M1 or M2 macrophages to the two bacteria tested. However, a difference in cytokine production between the two types of macrophages was found.

Quantitative risk assessment of the aggregate dermal exposure to the sensitizing fragrance geraniol in personal care products and household cleaning agents.

PubMed

Nijkamp, M M; Bokkers, B G H; Bakker, M I; Ezendam, J; Delmaar, J E

2015-10-01

A quantitative risk assessment was performed to establish if consumers are at risk for being dermally sensitized by the fragrance geraniol. Aggregate dermal exposure to geraniol was estimated using the Probabilistic Aggregate Consumer Exposure Model, containing data on the use of personal care products and household cleaning agents. Consumer exposure to geraniol via personal care products appeared to be higher than via household cleaning agents. The hands were the body parts receiving the highest exposure to geraniol. Dermal sensitization studies were assessed to derive the point of departure needed for the estimation of the Acceptable Exposure Level (AEL). Two concentrations were derived, one based on human studies and the other from dose-response analysis of the available murine local lymph node assay data. The aggregate dermal exposure assessment resulted in body part specific median exposures up to 0.041 μg/cm(2) (highest exposure 102 μg/cm(2)) for hands. Comparing the exposure to the lowest AEL (55 μg/cm(2)), shows that a range of 0.02-0.86% of the population may have an aggregated exposure which exceeds the AEL. Furthermore, it is demonstrated that personal care products contribute more to the consumer's geraniol exposure compared to household cleaning agents. Copyright © 2015 Elsevier Inc. All rights reserved.

Spatial and Temporal Uncertainty of Crop Yield Aggregations

NASA Technical Reports Server (NTRS)

Porwollik, Vera; Mueller, Christoph; Elliott, Joshua; Chryssanthacopoulos, James; Iizumi, Toshichika; Ray, Deepak K.; Ruane, Alex C.; Arneth, Almut; Balkovic, Juraj; Ciais, Philippe;

Benefits of aggregates surface modification in concrete production

NASA Astrophysics Data System (ADS)

Junak, J.; Sicakova, A.

2017-10-01

In our study, recycled concrete aggregates (RCA), which surfaces had been modified by geopolymer material based on coal fly ash, were used to produce the concrete samples. In these samples, fraction 4/8 mm was replaced by recycled concrete aggregate with a range of 100%. To modify the surface of RCA was “Solo” and “Triple stage” modification used. On these samples real density, total water absorption and compressive strength were examined after 28, 90, 180 and 365 days of hardening. The highest compressive strength 56.8 MPa, after 365 days hardening, reached sample which had improved RCA surface by “Triple stage mixing”.

Gut bacteria mediate aggregation in the German cockroach

PubMed Central

Wada-Katsumata, Ayako; Zurek, Ludek; Nalyanya, Godfrey; Roelofs, Wendell L.; Zhang, Aijun; Schal, Coby

2015-01-01

Aggregation of the German cockroach, Blattella germanica, is regulated by fecal aggregation agents (pheromones), including volatile carboxylic acids (VCAs). We demonstrate that the gut microbial community contributes to production of these semiochemicals. Chemical analysis of the fecal extract of B. germanica revealed 40 VCAs. Feces from axenic cockroaches (no microorganisms in the alimentary tract) lacked 12 major fecal VCAs, and 24 of the remaining compounds were represented at extremely low amounts. Olfactory and aggregation bioassays demonstrated that nymphs strongly preferred the extract of control feces over the fecal extract of axenic cockroaches. Additionally, nymphs preferred a synthetic blend of 6 fecal VCAs over a solvent control or a previously identified VCA blend. To test whether gut bacteria contribute to the production of fecal aggregation agents, fecal aerobic bacteria were cultured, isolated, and identified. Inoculation of axenic cockroaches with individual bacterial taxa significantly rescued the aggregation response to the fecal extract, and inoculation with a mix of six bacterial isolates was more effective than with single isolates. The results indicate that the commensal gut microbiota contributes to production of VCAs that act as fecal aggregation agents and that cockroaches discriminate among the complex odors that emanate from a diverse microbial community. Our results highlight the pivotal role of gut bacteria in mediating insect–insect communication. Moreover, because the gut microbial community reflects the local environment, local plasticity in fecal aggregation pheromones enables colony-specific odors and fidelity to persistent aggregation sites. PMID:26644557

75 FR 5760 - Proposed Information Collection; Comment Request; Western Alaska Community Development Quota Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-04

... Development Quota (CDQ) Program is an economic development program implemented under the Magnuson Stevens... Islands Management Area fisheries, to support economic development in western Alaska, to alleviate poverty and provide economic and social benefits for residents of western Alaska, and to achieve sustainable...

75 FR 4490 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-28

...; Quota Transfer AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric... granted safe harbor in Virginia due to poor weather conditions and a navigation hazard on January 2, 2010.... Emily H. Menashes, Acting Director, Office of Sustainable Fisheries, National Marine Fisheries Service...

78 FR 21584 - Atlantic Highly Migratory Species; 2013 Atlantic Bluefin Tuna Quota Specifications

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-11

... FMP). The 1999 FMP included a framework process to promulgate annual specifications for the BFT... percent of the 948.7-mt total U.S. quota). Accounting for Dead Discards The United States must report BFT... specifications. Accounting for dead discards in the Longline category in this way may provide further incentive...

New Mexico aggregate production sites, 1997-1999

USGS Publications Warehouse

Orris, Greta J.

2000-01-01

This report presents data, including latitude and longitude, for aggregate sites in New Mexico that were believed to be active in the period 1997-1999. The data are presented in paper form in Part A of this report and as Microsoft Excel 97 and Data Interchange Format (DIF) files in Part B. The work was undertaken as part of the effort to update information for the National Atlas. This compilation includes data from: the files of U.S. Geological Survey (USGS); company contacts; the New Mexico Bureau of Mines and Mineral Resources, New Mexico Bureau of Mine Inspection, and the Mining and Minerals Division of the New Mexico Energy, Minerals and Natural Resources Department (Hatton and others, 1998); the Bureau of Land Management Information; and direct communications with some of the aggregate operators. Additional information on most of the sites is available in Hatton and others (1998).

77 FR 15712 - Atlantic Highly Migratory Species; 2012 Atlantic Bluefin Tuna Quota Specifications

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-16

... information indicates an underharvest of the 2011 adjusted BFT quota. Final 2011 landings and dead discard... annual meeting, ICCAT recommended a TAC of 1,750 mt annually for 2011 and for 2012, inclusive of dead... column. Accounting for Dead Discards The United States must report BFT landings data and BFT dead discard...

Characterizing harmful advanced glycation end-products (AGEs) and ribosylated aggregates of yellow mustard seed phytocystatin: Effects of different monosaccharides.

PubMed

Ahmed, Azaj; Shamsi, Anas; Bano, Bilqees

2017-01-15

Advanced glycation end products (AGEs) are at the core of variety of diseases ranging from diabetes to renal failure and hence gaining wide consideration. This study was aimed at characterizing the AGEs of phytocystatin isolated from mustard seeds (YMP) when incubated with different monosaccharides (glucose, ribose and mannose) using fluorescence, ultraviolet, circular dichroism (CD) spectroscopy and microscopy. Ribose was found to be the most potent glycating agent as evident by AGEs specific fluorescence and absorbance. YMP exists as a molten globule like structure on day 24 as depicted by high ANS fluorescence and altered intrinsic fluorescence. Glycated YMP as AGEs and ribose induced aggregates were observed at day 28 and 32 respectively. In our study we have also examined the anti-aggregative potential of polyphenol, resveratrol. Our results suggested the anti-aggregative behavior of resveratrol as it prevented the in vitro aggregation of YMP, although further studies are required to decode the mechanism by which resveratrol prevents the aggregation. Copyright © 2016 Elsevier B.V. All rights reserved.

78 FR 64198 - Fisheries of the Northeastern United States; Tilefish Fishery; 2014 Tilefish Fishing Quota...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-28

... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration RIN 0648-XC887 Fisheries of the Northeastern United States; Tilefish Fishery; 2014 Tilefish Fishing Quota Specification AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric Administration (NOAA), Commerce...

Designing cross-linked xylanase aggregates for bioconversion of agroindustrial waste biomass towards potential production of nutraceuticals.

PubMed

Hero, J S; Romero, C M; Pisa, J H; Perotti, N I; Olivaro, C; Martinez, M A

2018-05-01

Immobilized biocatalysts design has the potential to efficiently produce valuable bioproducts from lignocellulosic biomass. Among them, the carrier-free immobilization through the cross-linked enzyme aggregates technology is a simple and low-cost alternative. A two steps statistical approach was utilized to evaluate the synthesis of a cross-linked enzyme aggregate from a xylanolytic preparation, which was produced by Cohnella sp. AR92 grown in a peptone-based culture medium. The resulting immobilized biocatalyst, Xyl-CLEA, was significate more stable (25 to 45%) towards temperatures up to 50°C with respect to the free enzyme, and retained over 50% of its initial activity after 5 consecutive cycles of reuse. By means of infrared spectroscopy and electron microscopy, the Xyl-CLEA showed architectural features described as signature of type I and type II of protein aggregates. These, were the result of the simultaneous aggregation of a multiplicity of proteins from the crude enzymatic extract. The enzymatic activity was assessed using alkali pretreated sugar cane bagasse as substrate. Whereas the free enzymatic preparation released xylose as the main product, the immobilized xylanase produced xylooligosaccharides, thus showing that the immobilization procedure modified the potential application of the extracellular xylanase from Conhella sp. AR92. Copyright © 2018 Elsevier B.V. All rights reserved.

75 FR 82295 - Fisheries of the Northeastern United States; Atlantic Bluefish Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-30

.... 100204079-0199-02] RIN 0648-XA084 Fisheries of the Northeastern United States; Atlantic Bluefish Fishery... the Commonwealth of Virginia is transferring commercial bluefish quota to the State of North Carolina... INFORMATION: Regulations governing the Atlantic bluefish fishery are found at 50 CFR part 648. The regulations...

75 FR 76925 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-10

.... 0908191244-91427-02] RIN 0648-XA070 Fisheries of the Northeastern United States; Summer Flounder Fishery... is transferring a portion of its 2010 commercial summer flounder quota to the Commonwealth of... governing the summer flounder fishery are found at 50 CFR part 648. The regulations require annual...

78 FR 9849 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-12

.... 111220786-1781-01] RIN 0648-XC451 Fisheries of the Northeastern United States; Summer Flounder Fishery... of North Carolina is retroactively transferring a portion of its 2012 commercial summer flounder... summer flounder fishery are in 50 CFR part 648, and require annual specification of a commercial quota...

Losses from effluent taxes and quotas under uncertainty

USGS Publications Warehouse

Watson, W.D.; Ridker, R.G.

1984-01-01

Recent theoretical papers by Adar and Griffin (J. Environ. Econ. Manag.3, 178-188 (1976)), Fishelson (J. Environ. Econ. Manag.3, 189-197 (1976)), and Weitzman (Rev. Econ. Studies41, 477-491 (1974)) show that,different expected social losses arise from using effluent taxes and quotas as alternative control instruments when marginal control costs are uncertain. Key assumptions in these analyses are linear marginal cost and benefit functions and an additive error for the marginal cost function (to reflect uncertainty). In this paper, empirically derived nonlinear functions and more realistic multiplicative error terms are used to estimate expected control and damage costs and to identify (empirically) the mix of control instruments that minimizes expected losses. ?? 1984.

76 FR 56120 - Atlantic Highly Migratory Species; North and South Atlantic Swordfish Quotas

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-12

... Contracting Parties. Contracting Parties may restrict fishermen to a minimum size of 25 kg live weight OR 125... restrict fishermen to a minimum size of 15 kg live weight OR 119 cm LJFL with no tolerance. In 2009, NMFS... quota, among other things. Per the ATCA, the United States is obligated to implement ICCAT-approved...

Entrapment of Aβ1-40 peptide in unstructured aggregates

NASA Astrophysics Data System (ADS)

Corsale, C.; Carrotta, R.; Mangione, M. R.; Vilasi, S.; Provenzano, A.; Cavallaro, G.; Bulone, D.; San Biagio, P. L.

2012-06-01

Recognizing the complexity of the fibrillogenesis process provides a solid ground for the development of therapeutic strategies aimed at preventing or inhibiting protein-protein aggregation. Under this perspective, it is meaningful to identify the possible aggregation pathways and their relative products. We found that Aβ-peptide dissolved in a pH 7.4 solution at small peptide concentration and low ionic strength forms globular aggregates without typical amyloid β-conformation. ThT binding kinetics was used to monitor aggregate formation. Circular dichroism spectroscopy, AFM imaging, static and dynamic light scattering were used for structural and morphological characterization of the aggregates. They appear stable or at least metastable with respect to fiber growth, therefore appearing as an incidental product in the pathway of fibrillogenesis.

76 FR 61472 - Revised Fiscal Year 2011 Tariff-Rate Quota Allocations for Refined Sugar

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-04

... Allocations for Refined Sugar AGENCY: Office of the United States Trade Representative. ACTION: Notice... (TRQ) for imported refined sugar for entry through November 30, 2011. DATES: Effective Date: October 4... States maintains a tariff-rate quota for imports of refined sugar. Section 404(d)(3) of the Uruguay Round...

76 FR 17032 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-28

.... 101029427-0609-02] RIN 0648-XA301 Fisheries of the Northeastern United States; Summer Flounder Fishery... of North Carolina is transferring a portion of its 2010 and 2011 commercial summer flounder quotas to the Commonwealth of Virginia. Vessels were authorized by Virginia to land summer flounder under safe...

78 FR 33 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-02

.... 111220786-1781-01] RIN 0648-XC396 Fisheries of the Northeastern United States; Summer Flounder Fishery... of North Carolina is transferring a portion of its 2012 commercial summer flounder quota to the Commonwealth of Virginia, the State of North Carolina is transferring a portion of its 2012 commercial summer...

78 FR 20037 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-03

.... 121009528-2729-02] RIN 0648-XC542 Fisheries of the Northeastern United States; Summer Flounder Fishery... of North Carolina is transferring a portion of its 2013 commercial summer flounder quota to the.... SUPPLEMENTARY INFORMATION: Regulations governing the summer flounder fishery are in 50 CFR part 648, and require...

76 FR 81851 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-29

.... 101029427-0609-02] RIN 0648-XA884 Fisheries of the Northeastern United States; Summer Flounder Fishery... of North Carolina is transferring a portion of its 2011 commercial summer flounder quota to the...: Regulations governing the summer flounder fishery are found at 50 CFR part 648. The regulations require annual...

78 FR 13812 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-01

.... 121009528-2729-02] RIN 0648-XC499 Fisheries of the Northeastern United States; Summer Flounder Fishery... of North Carolina is transferring a portion of its 2013 commercial summer flounder quota to the.... SUPPLEMENTARY INFORMATION: Regulations governing the summer flounder fishery are in 50 CFR part 648, and require...

76 FR 81851 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-29

.... 101029427-0609-02] RIN 0648-XA887 Fisheries of the Northeastern United States; Summer Flounder Fishery... of Maine is transferring portions of their 2011 commercial summer flounder quota to the State of...: Regulations governing the summer flounder fishery are found at 50 CFR part 648. The regulations require annual...

75 FR 2820 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-19

.... 0809251266-81485-02] RIN 0648-XT61 Fisheries of the Northeastern United States; Summer Flounder Fishery... of North Carolina is transferring a portion of its 2009 commercial summer flounder quota to the...: Regulations governing the summer flounder fishery are found at 50 CFR part 648. The regulations require annual...

77 FR 14481 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-12

.... 111220786-1781-01] RIN 0648-XB026 Fisheries of the Northeastern United States; Summer Flounder Fishery... of North Carolina is transferring a portion of its 2012 commercial summer flounder quota to the...: Regulations governing the summer flounder fishery are found at 50 CFR part 648. The regulations require annual...

75 FR 22025 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-27

.... 0908191244-91427-02] RIN 0648-XV91 Fisheries of the Northeastern United States; Summer Flounder Fishery... of North Carolina is transferring a portion of its 2010 commercial summer flounder quota to the...: Regulations governing the summer flounder fishery are found at 50 CFR part 648. The regulations require annual...

76 FR 23206 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-26

.... 101029427-0609-02] RIN 0648-XA371 Fisheries of the Northeastern United States; Summer Flounder Fishery... of North Carolina is transferring a portion of its 2011 commercial summer flounder quota to the Commonwealth of Virginia. Vessels from North Carolina were authorized by Virginia to land summer flounder under...

77 FR 25103 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-27

.... 111220786-1781-01] RIN 0648-XC002 Fisheries of the Northeastern United States; Summer Flounder Fishery... of North Carolina is transferring a portion of its 2012 commercial summer flounder quota to the... governing the summer flounder fishery are in 50 CFR part 648, and require annual specification of a...

75 FR 30739 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-02

.... 0908191244-91427-02] RIN 0648-XW47 Fisheries of the Northeastern United States; Summer Flounder Fishery... of North Carolina is transferring a portion of its 2010 commercial summer flounder quota to the...: Regulations governing the summer flounder fishery are found at 50 CFR part 648. The regulations require annual...

';Best' Practices for Aggregating Subset Results from Archived Datasets

NASA Astrophysics Data System (ADS)

Baskin, W. E.; Perez, J.

2013-12-01

In response to the exponential growth in science data analysis and visualization capabilities Data Centers have been developing new delivery mechanisms to package and deliver large volumes of aggregated subsets of archived data. New standards are evolving to help data providers and application programmers deal with growing needs of the science community. These standards evolve from the best practices gleaned from new products and capabilities. The NASA Atmospheric Sciences Data Center (ASDC) has developed and deployed production provider-specific search and subset web applications for the CALIPSO, CERES, TES, and MOPITT missions. This presentation explores several use cases that leverage aggregated subset results and examines the standards and formats ASDC developers applied to the delivered files as well as the implementation strategies for subsetting and processing the aggregated products. The following topics will be addressed: - Applications of NetCDF CF conventions to aggregated level 2 satellite subsets - Data-Provider-Specific format requirements vs. generalized standards - Organization of the file structure of aggregated NetCDF subset output - Global Attributes of individual subsetted files vs. aggregated results - Specific applications and framework used for subsetting and delivering derivative data files

Amyloid-beta aggregation: selective inhibition of aggregation in mixtures of amyloid with different chain lengths.

PubMed Central

Snyder, S W; Ladror, U S; Wade, W S; Wang, G T; Barrett, L W; Matayoshi, E D; Huffaker, H J; Krafft, G A; Holzman, T F

1994-01-01

One of the clinical manifestations of Alzheimer's disease is the deposition of the 39-43 residue amyloid-beta (A beta) peptide in aggregated fibrils in senile plaques. Characterization of the aggregation behavior of A beta is one of the critical issues in understanding the role of A beta in the disease process. Using solution hydrodynamics, A beta was observed to form three types of species in phosphate-buffered saline: insoluble aggregates with sedimentation coefficients of approximately 50,000 S and molecular masses of approximately 10(9) Da, "soluble aggregates" with sedimentation coefficients of approximately 30 S and masses of approximately 10(6) Da, and monomer. When starting from monomer, the aggregation kinetics of A beta 1-40 (A beta 40) and A beta 1-42 (A beta 42), alone and in combination, reveal large differences in the tendency of these peptides to aggregate as a function of pH and other solution conditions. At pH 4.1 and 7.0-7.4, aggregation is significantly slower than at pH 5 and 6. Under all conditions, aggregation of the longer A beta 42 was more rapid than A beta 40. Oxidation of Met-35 to the sulfoxide in A beta 40 enhances the aggregation rate over that of the nonoxidized peptide. Aggregation was found to be dependent upon temperature and to be strongly dependent on peptide concentration and ionic strength, indicating that aggregation is driven by a hydrophobic effect. When A beta 40 and A beta 42 are mixed together, A beta 40 retards the aggregation of A beta 42 in a concentration-dependent manner. Shorter fragments have a decreasing ability to interfere with A beta 42 aggregation. Conversely, the rate of aggregation of A beta 40 can be significantly enhanced by seeding slow aggregating solutions with preformed aggregates of A beta 42. Taken together, the inhibition of A beta 42 aggregation by A beta 40, the seeding of A beta 40 aggregation by A beta 42 aggregates, and the chemical oxidation of A beta 40 suggest that the relative abundance and

78 FR 72585 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Commercial Quota Harvested...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-03

.... 111220786-1781-01] RIN 0648-XD004 Fisheries of the Northeastern United States; Summer Flounder Fishery...: NMFS announces that the 2013 summer flounder commercial quota allocated to the Commonwealth of Virginia has been harvested. Vessels issued a commercial Federal fisheries [[Page 72586

Commercial Demonstration of the Manufactured Aggregate Processing Technology Utilizing Spray Dryer Ash

DOE Office of Scientific and Technical Information (OSTI.GOV)

Milton Wu; Paul Yuran

2006-12-31

Universal Aggregates LLC (UA) was awarded a cost sharing Co-operative Agreement from the Department of Energy (DOE) through the Power Plant Improvement Initiative Program (PPII) to design, construct and operate a lightweight aggregate manufacturing plant at the Birchwood Power Facility in King George, Virginia in October 2001. The Agreement was signed in November 2002. The installation and start-up expenses for the Birchwood Aggregate Facility are $19.5 million. The DOE share is $7.2 million (37%) and the UA share is $12.3 million (63%). The original project team consists of UA, SynAggs, LLC, CONSOL Energy Inc. and P. J. Dick, Inc. Usingmore » 115,000 ton per year of spray dryer ash (SDA), a dry FGD by-product from the power station, UA will produce 167,000 tons of manufactured lightweight aggregate for use in production of concrete masonry units (CMU). Manufacturing aggregate from FGD by-products can provide an economical high-volume use and substantially expand market for FGD by-products. Most of the FGD by-products are currently disposed of in landfills. Construction of the Birchwood Aggregate Facility was completed in March 2004. Operation startup was begun in April 2004. Plant Integration was initiated in December 2004. Integration includes mixing, extrusion, curing, crushing and screening. Lightweight aggregates with proper size gradation and bulk density were produced from the manufacturing aggregate plant and loaded on a stockpile for shipment. The shipped aggregates were used in a commercial block plant for CMU production. However, most of the production was made at low capacity factors and for a relatively short time in 2005. Several areas were identified as important factors to improve plant capacity and availability. Equipment and process control modifications and curing vessel clean up were made to improve plant operation in the first half of 2006. About 3,000 tons of crushed aggregate was produced in August 2006. UA is continuing to work to improve

Production efficiencies of U.S. electric generation plants: Effects of data aggregation and greenhouse gas and renewable energy policy

NASA Astrophysics Data System (ADS)

Lynes, Melissa Kate

Over the last few decades there has been a shift in electricity production in the U.S. Renewable energy sources are becoming more widely used. In addition, electric generation plants that use coal inputs are more heavily regulated than a couple decades ago. This shift in electricity production was brought on by changes in federal policy -- a desire for electricity produced in the U.S. which led to policies being adopted that encourage the use of renewable energy. The change in production practices due to policies may have led to changes in the productivity of electric generation plants. Multiple studies have examined the most efficient electric generation plants using the data envelopment analysis (DEA) approach. This study builds on past research to answer three questions: 1) Does the level of aggregation of fuel input variables affect the plant efficiency scores and how does the efficiency of renewable energy input compare to nonrenewable energy inputs; 2) Are policies geared toward directly or indirectly reducing greenhouse gas emissions affecting the production efficiencies of greenhouse gas emitting electric generation plants; and 3) Do renewable energy policies and the use of intermittent energy sources (i.e. wind and solar) affect the productivity growth of electric generation plants. All three analysis, presented in three essays, use U.S. plant level data obtained from the Energy Information Administration to answer these questions. The first two essays use DEA to determine the pure technical, overall technical, and scale efficiencies of electric generation plants. The third essay uses DEA within the Malmquist index to assess the change in productivity over time. Results indicate that the level of aggregation does matter particularly for scale efficiency. This implies that valuable information is likely lost when fuel inputs are aggregated together. Policies directly focused on reducing greenhouse gas emissions may improve the production efficiencies of

77 FR 69567 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-20

.... 111220786-1781-01] RIN 0648-XC340 Fisheries of the Northeastern United States; Summer Flounder Fishery... of North Carolina is transferring a portion of its 2012 commercial summer flounder quota to the State... governing the summer flounder fishery are in 50 CFR part 648, and require annual specification of a...

78 FR 76765 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Quota Transfer

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-19

.... 121009528-2729-02] RIN 0648-XD025 Fisheries of the Northeastern United States; Summer Flounder Fishery... of Maryland is transferring a portion of its 2013 commercial summer flounder quota to the State of... governing the summer flounder fishery are in 50 CFR part 648, and require annual specification of a...

Does bathymetry drive coastal whale shark (Rhincodon typus) aggregations?

PubMed Central

Stewart, Bryce D.; McClean, Colin J.; Hancock, James; Rees, Richard

2018-01-01

Background The whale shark (Rhincodon typus) is known to aggregate in a number of coastal locations globally, however what causes these aggregations to form where they do is largely unknown. This study examines whether bathymetry is an important driver of coastal aggregation locations for R. typus through bathymetry’s effect on primary productivity and prey availability. This is a global study taking into account all coastal areas within R. typus’ range. Methods R. typus aggregation locations were identified through an extensive literature review. Global bathymetric data were compared at R. typus aggregation locations and a large random selection of non-aggregation areas. Generalised linear models were used to assess which bathymetric characteristic had the biggest influence on aggregation presence. Results Aggregation sites were significantly shallower than non-aggregation sites and in closer proximity to deep water (the mesopelagic zone) by two orders of magnitude. Slope at aggregation sites was significantly steeper than non-aggregation sites. These three bathymetric variables were shown to have the biggest association with aggregation sites, with up to 88% of deviation explained by the GLMs. Discussion The three key bathymetric characteristics similar at the aggregation sites are known to induce upwelling events, increase primary productivity and consequently attract numerous other filter feeding species. The location of aggregation sites in these key areas can be attributed to this increased prey availability, thought to be the main reason R. typus aggregations occur, extensively outlined in the literature. The proximity of aggregations to shallow areas such as reefs could also be an important factor why whale sharks thermoregulate after deep dives to feed. These findings increase our understanding of whale shark behaviour and may help guide the identification and conservation of further aggregation sites.

Transportation and utilization of aggregates for road construction

NASA Astrophysics Data System (ADS)

Fladvad, Marit; Wigum, Børge Johannes; Aurstad, Joralf

2017-04-01

Road construction relies on non-renewable aggregate resources as the main construction material. Sources for high-quality aggregate resources are scattered, and requirements for aggregate quality can cause long transport distances between quarry and road construction site. In European countries, the average aggregate consumption per capita is 5 tonnes per year (European Aggregates Association, 2016), while the corresponding figure for Norway is 11 tonnes (Neeb, 2015). Half the Norwegian aggregate production (sand, gravel and crushed rock) is used for road construction. In Norway, aggregate resources have been considered abundant. However, stricter requirement for aggregate quality, and increased concern for sustainability and environmental issues have spurred focus on reduction of transport lengths through better utilization of local aggregate materials. In this research project, information about pavement design and aggregate quality requirements were gathered from a questionnaire sent to selected experts from the World Road Organization (PIARC), European Committee for Standardization (CEN), and Nordic Road Association (NVF). The gathered data was compared to identify differences and similarities for aggregate use in the participating countries. Further, the data was compared to known data from Norway regarding: - amount of aggregates required for a road structure - aggregate transport lengths and related costs A total of 18 countries participated in the survey, represented by either road authorities, research institutions, or contractors. There are large variations in practice for aggregate use among the represented countries, and the selection of countries is sufficient to illustrate a variety in pavement designs, aggregate sizes, and quality requirements for road construction. There are considerable differences in both pavement thickness and aggregate sizes used in the studied countries. Total thicknesses for pavement structures varies from 220 mm to 2400 mm

Prediction of the aggregation propensity of proteins from the primary sequence: aggregation properties of proteomes.

PubMed

Castillo, Virginia; Graña-Montes, Ricardo; Sabate, Raimon; Ventura, Salvador

2011-06-01

In the cell, protein folding into stable globular conformations is in competition with aggregation into non-functional and usually toxic structures, since the biophysical properties that promote folding also tend to favor intermolecular contacts, leading to the formation of β-sheet-enriched insoluble assemblies. The formation of protein deposits is linked to at least 20 different human disorders, ranging from dementia to diabetes. Furthermore, protein deposition inside cells represents a major obstacle for the biotechnological production of polypeptides. Importantly, the aggregation behavior of polypeptides appears to be strongly influenced by the intrinsic properties encoded in their sequences and specifically by the presence of selective short regions with high aggregation propensity. This allows computational methods to be used to analyze the aggregation properties of proteins without the previous requirement for structural information. Applications range from the identification of individual amyloidogenic regions in disease-linked polypeptides to the analysis of the aggregation properties of complete proteomes. Herein, we review these theoretical approaches and illustrate how they have become important and useful tools in understanding the molecular mechanisms underlying protein aggregation. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

78 FR 76766 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Commercial Quota Harvested...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-19

.... 111220786-1781-01] RIN 0648-XD030 Fisheries of the Northeastern United States; Summer Flounder Fishery...: NMFS announces that the 2013 summer flounder commercial quota allocated to the State of New Jersey has been harvested. Vessels issued a commercial Federal fisheries permit for the summer flounder fishery...

77 FR 64239 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Commercial Quota Harvested...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-19

.... 111220786-1781-01] RIN 0648-XC294 Fisheries of the Northeastern United States; Summer Flounder Fishery...: NMFS announces that the 2012 summer flounder commercial quota allocated to the State of New York has been harvested. Vessels issued a commercial Federal fisheries permit for the summer flounder fishery...

77 FR 75569 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Commercial Quota Harvested...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-21

.... 111220786-1781-01] RIN 0648-XC404 Fisheries of the Northeastern United States; Summer Flounder Fishery...: NMFS announces that the 2012 summer flounder commercial quota allocated to the State of New Jersey has been harvested. Vessels issued a commercial Federal fisheries permit for the summer flounder fishery...

77 FR 52262 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Commercial Quota Harvested...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-29

.... 111220786-1781-01] RIN 0648-XC176 Fisheries of the Northeastern United States; Summer Flounder Fishery...; closure. SUMMARY: NMFS announces that the 2012 summer flounder commercial quota allocated to the... summer flounder fishery may not land summer flounder in Massachusetts for the remainder of calendar year...

75 FR 52890 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Commercial Quota Harvested...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-30

.... 0908191244-91427ndash;02] RIN 0648-XY35 Fisheries of the Northeastern United States; Summer Flounder Fishery...; closure. SUMMARY: NMFS announces that the 2010 summer flounder commercial quota allocated to the... summer flounder fishery may not land summer flounder in Massachusetts for the remainder of calendar year...

78 FR 51096 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Commercial Quota Harvested...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-20

.... 111220786-1781-01] RIN 0648-XC811 Fisheries of the Northeastern United States; Summer Flounder Fishery...; closure. SUMMARY: NMFS announces that the 2013 summer flounder commercial quota allocated to the... summer flounder fishery may not land summer flounder in Massachusetts for the remainder of calendar year...

78 FR 59626 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Commercial Quota Harvested...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-27

.... 111220786-1781-01] RIN 0648-XC878 Fisheries of the Northeastern United States; Summer Flounder Fishery...: NMFS announces that the 2013 summer flounder commercial quota allocated to the State of New York has been harvested. Vessels issued a commercial Federal fisheries permit for the summer flounder fishery...

78 FR 70890 - Fisheries of the Northeastern United States; Summer Flounder Fishery; Commercial Quota Harvested...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-27

.... 111220786-1781-01] RIN 0648-XC998 Fisheries of the Northeastern United States; Summer Flounder Fishery...: NMFS announces that the 2013 summer flounder commercial quota allocated to the State of New Jersey has been harvested. Vessels issued a commercial Federal fisheries permit for the summer flounder fishery...

Implementation and Incentive of Education Policies: Experience from the High School Admissions Quota Allocation Policy

ERIC Educational Resources Information Center

Shiyue, Wang

2017-01-01

Improving administrative efficiency is the core problem in administrative governance. This case study of quota allocation policy implementation in City A reveals that a set of education policy implementation and incentive mechanisms revolving around responsibility contracts and target evaluations has already taken shape, to guarantee effective…

Natural aggregates of the conterminous United States

USGS Publications Warehouse

Langer, William H.

1988-01-01

adversely when used as concrete aggregate. In areas where suitable natural aggregate is not available or accessible, it may become necessary to improve the quality of existing aggregate, to import aggregate from outside the area, or to substitute artificial aggregate for natural aggregate. In most cases, all of these alternatives add substantially to the cost of the final product. Even though an area may be blessed with an abundance of aggregate suitable for the intended purpose, existing land uses, zoning, or regulations may preclude commercial exploitation of the aggregate. This report also discusses the aggregate industry in general terms, including exploration, mining, and processing, as well as aggregate production rates. Proper long-range planning based on an understanding of the aggregate industry can help assure adequate supplies of aggregate.

China's Rare Earth Supply Chain: Illegal Production, and Response to new Cerium Demand

NASA Astrophysics Data System (ADS)

Nguyen, Ruby Thuy; Imholte, D. Devin

2016-07-01

As the demand for personal electronic devices, wind turbines, and electric vehicles increases, the world becomes more dependent on rare earth elements. Given the volatile, Chinese-concentrated supply chain, global attempts have been made to diversify supply of these materials. However, the overall effect of supply diversification on the entire supply chain, including increasing low-value rare earth demand, is not fully understood. This paper is the first attempt to shed some light on China's supply chain from both demand and supply perspectives, taking into account different Chinese policies such as mining quotas, separation quotas, export quotas, and resource taxes. We constructed a simulation model using Powersim Studio that analyzes production (both legal and illegal), production costs, Chinese and rest-of-world demand, and market dynamics. We also simulated new demand of an automotive aluminum-cerium alloy in the US market starting from 2018. Results showed that market share of the illegal sector has grown since 2007-2015, ranging between 22% and 25% of China's rare earth supply, translating into 59-65% illegal heavy rare earths and 14-16% illegal light rare earths. There will be a shortage in certain light and heavy rare earths given three production quota scenarios and constant demand growth rate from 2015 to 2030. The new simulated Ce demand would require supply beyond that produced in China. Finally, we illustrate revenue streams for different ore compositions in China in 2015.

Sound production by dusky grouper Epinephelus marginatus at spawning aggregation sites.

PubMed

Bertucci, F; Lejeune, P; Payrot, J; Parmentier, E

2015-08-01

Sound production by the dusky grouper Epinephelus marginatus was monitored both in captivity and at two Mediterranean spawning sites during the summers of 2012 and 2013. The results of long-term passive acoustic recordings provide for the first time a description of the sounds produced by E. marginatus. Two types of sounds were mainly recorded and consisted of low-frequency booms that can be produced singly or in series with dominant frequencies below 100 Hz. Recordings in captivity validated these sounds as belonging to E. marginatus and suggested that they may be associated with reproductive displays usually performed during early stages of courtship behaviour. This study also allowed the identification of a third, low-frequency growl-like type of sound typically found in other grouper species. These growls were, however, not recorded in tanks and it is cautiously proposed that they are produced by E. marginatus. Acoustic signals attributed to E. marginatus were produced throughout the spawning season, with a diel pattern showing an increase before dusk, i.e., from 1900 to 2200 hours, before decreasing until the morning. The occurrence of sounds during the spawning season of this species suggests that they are probably involved in social activity occurring close to aggregation sites. Passive acoustics offer a helpful tool to monitor aggregation sites of this emblematic species in order to improve conservation efforts. © 2015 The Fisheries Society of the British Isles.

COMMERCIAL DEMONSTRATION OF THE MANUFACTURED AGGREGATE PROCESSING TECHNOLOGY UTILIZING SPRAY DRYER ASH

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roy Scandrol

2003-10-01

Universal Aggregates, LLC proposes to design, construct and operate a lightweight aggregate manufacturing plant at the Birchwood Power Facility in King George, Virginia. The installation and start-up expenses for the Birchwood Aggregate Facility are $19.5 million. The DOE share is $7.2 million (37%) and the Universal Aggregates share is $12.3 (63%). The project team consists of CONSOL Energy Inc., P.J. Dick, Inc., SynAggs, LLC, and Universal Aggregates, LLC. The Birchwood Facility will transform 115,000 tons per year of spray dryer by-products that are currently being disposed of in an offsite landfill into 167,000 tons of a useful product, lightweight aggregatesmore » that can be used to manufacture lightweight aggregates that can be used to manufacture lightweight and medium weight masonry blocks. In addition to the environmental benefits, the Birchwood Facility will create nine (9) manufacturing jobs plus additional employment in the local trucking industry to deliver the aggregate to customers or reagents to the facility. A successful demonstration would lead to additional lightweight aggregate manufacturing facilities in the United States. There are currently twenty-one (21) spray dryer facilities operating in the United States that produce an adequate amount of spray dryer by-product to economically justify the installation of a lightweight aggregate manufacturing facility. Industry sources believe that as additional scrubbing is required, dry FGD technologies will be the technology of choice. Letters from potential lightweight aggregate customers indicate that there is a market for the product once the commercialization barriers are eliminated by this demonstration project.« less

76 FR 39019 - Atlantic Highly Migratory Species; Atlantic Bluefin Tuna Quotas and Atlantic Tuna Fisheries...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-05

... for the more selective, directed fishing categories, and be a de facto reallocation of quota shares... allowing a de facto ``incidental catch'' fishery in the Gulf of Mexico, in violation of the ICCAT... regarding post-release mortality, makes it difficult to quantify now the effect of the weak hook requirement...

Mechanical properties of concrete containing recycled concrete aggregate (RCA) and ceramic waste as coarse aggregate replacement

NASA Astrophysics Data System (ADS)

Khalid, Faisal Sheikh; Azmi, Nurul Bazilah; Sumandi, Khairul Azwa Syafiq Mohd; Mazenan, Puteri Natasya

2017-10-01

Many construction and development activities today consume large amounts of concrete. The amount of construction waste is also increasing because of the demolition process. Much of this waste can be recycled to produce new products and increase the sustainability of construction projects. As recyclable construction wastes, concrete and ceramic can replace the natural aggregate in concrete because of their hard and strong physical properties. This research used 25%, 35%, and 45% recycled concrete aggregate (RCA) and ceramic waste as coarse aggregate in producing concrete. Several tests, such as concrete cube compression and splitting tensile tests, were also performed to determine and compare the mechanical properties of the recycled concrete with those of the normal concrete that contains 100% natural aggregate. The concrete containing 35% RCA and 35% ceramic waste showed the best properties compared with the normal concrete.

77 FR 58051 - Fisheries of the Northeastern United States; Bluefish Fishery; Commercial Quota Harvested for the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-19

.... 120201086-2418-02] RIN 0648-XC236 Fisheries of the Northeastern United States; Bluefish Fishery; Commercial...: NMFS announces that the 2012 bluefish commercial quota allocated to the Commonwealth of Massachusetts has been harvested. Vessels issued a commercial Federal fisheries permit for the bluefish fishery may...

[Dependence of rumen fatty acid production on the composition of rations].

PubMed

Lebzien, P; Rohr, K; Oslage, H J

1981-10-01

In three experiments with two Black-and-White dairy cows the influence of soybean oil and coconut fat as well as that of rations rich in roughage and concentrated feed on the production of fatty acids were determined with the isotope dilution method. A change in the method of sampling from the rumen in the course of the investigations resulted in distinctly different absolute production quotas, which can presumably be traced back to the disproportionate mixing in of the isotope and/or different production quotas in various regions of the rumen. The relative differences between the production quotas dependent on the rations, however were approximately the same with both sampling methods, so that they make the comparison of the rations concerning rumen fermentation possible. The production of acetic acid and the total production of fatty acids (C2--C4) correlated closely both with the intake of digestible energy and the intake of digestible organic matter. There was also a highly significant correlation o that they make the comparison of the rations concerning rumen fermentation possible. The production of acetic acid and the total production of fatty acids (C2--C4) correlated closely both with the intake of digestible energy and the intake of digestible organic matter. There was also a highly significant correlation o that they make the comparison of the rations concerning rumen fermentation possible. The production of acetic acid and the total production of fatty acids (C2--C4) correlated closely both with the intake of digestible energy and the intake of digestible organic matter. There was also a highly significant correlation between the relation of acetic and propionic acid in the rumen fluid and the quotient from acetic and propionic acid produced. In contrast to this, a significant relation between the concentration of fatty acids and the production of fatty acids could not be ascertained. Soybean oil and coconut fat brought about a slightly better

China’s rare earth supply chain: Illegal production, and response to new cerium demand

DOE PAGES

Nguyen, Ruby Thuy; Imholte, D. Devin

2016-03-29

As the demand for personal electronic devices, wind turbines, and electric vehicles increases, the world becomes more dependent on rare earth elements. Given the volatile, Chinese-concentrated supply chain, global attempts have been made to diversify supply of these materials. However, the overall effect of supply diversification on the entire supply chain, including increasing low-value rare earth demand, is not fully understood. This paper is the first attempt to shed some light on China’s supply chain from both demand and supply perspectives, taking into account different Chinese policies such as mining quotas, separation quotas, export quotas, and resource taxes. We constructedmore » a simulation model using Powersim Studio that analyzes production (both legal and illegal), production costs, Chinese and rest-of-world demand, and market dynamics. We also simulated new demand of an automotive aluminum-cerium alloy in the U.S. market starting from 2018. Results showed that market share of the illegal sector has grown since 2007 to 2015, ranging between 22% and 25% of China’s rare earth supply, translating into 59–65% illegal heavy rare earths and 14–16% illegal light rare earths. There would be a shortage in certain light and heavy rare earths given three production quota scenarios and constant demand growth rate from 2015 to 2030. The new simulated Ce demand would require supply beyond that produced in China. Lastly, we illustrated revenue streams for different ore compositions in China in 2015.« less

China’s rare earth supply chain: Illegal production, and response to new cerium demand

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nguyen, Ruby Thuy; Imholte, D. Devin

As the demand for personal electronic devices, wind turbines, and electric vehicles increases, the world becomes more dependent on rare earth elements. Given the volatile, Chinese-concentrated supply chain, global attempts have been made to diversify supply of these materials. However, the overall effect of supply diversification on the entire supply chain, including increasing low-value rare earth demand, is not fully understood. This paper is the first attempt to shed some light on China’s supply chain from both demand and supply perspectives, taking into account different Chinese policies such as mining quotas, separation quotas, export quotas, and resource taxes. We constructedmore » a simulation model using Powersim Studio that analyzes production (both legal and illegal), production costs, Chinese and rest-of-world demand, and market dynamics. We also simulated new demand of an automotive aluminum-cerium alloy in the U.S. market starting from 2018. Results showed that market share of the illegal sector has grown since 2007 to 2015, ranging between 22% and 25% of China’s rare earth supply, translating into 59–65% illegal heavy rare earths and 14–16% illegal light rare earths. There would be a shortage in certain light and heavy rare earths given three production quota scenarios and constant demand growth rate from 2015 to 2030. The new simulated Ce demand would require supply beyond that produced in China. Lastly, we illustrated revenue streams for different ore compositions in China in 2015.« less

78 FR 59878 - Atlantic Highly Migratory Species; Commercial Atlantic Aggregated Large Coastal Shark (LCS...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-30

... submitted electronically on a weekly basis through a NMFS-approved electronic reporting system by the dealer... metric tons (mt) dressed weight (dw) (149,914 lb dw) of non-blacknose SCS quota from the Atlantic region... lb dw), the Atlantic hammerhead shark management group quota is 27.1 metric tons (mt) dressed weight...

Development of long-term primary cell aggregates from Mediterranean octocorals.

PubMed

Huete-Stauffer, Carla; Valisano, Laura; Gaino, Elda; Vezzulli, Luigi; Cerrano, Carlo

2015-09-01

In lower metazoans, the aggregative properties of dissociated cells leading to in vitro stable multicellular aggregates have furnished a remarkable experimental material to carry out investigations in various research fields. One of the main expectations is to find good models for the study in vitro of the first steps of biomineralization processes. In this study, we examined five common Mediterranean gorgonians (Paramuricea clavata, Corallium rubrum, Eunicella singularis, Eunicella cavolinii, and Eunicella verrucosa) using mechanical cell aggregate production techniques. In particular, we investigated the conditions of aggregate formation, their number and survival in experimental conditions, the DNA synthesizing activity using 5'-bromo-2'-deoxyuridine (BrdU) tests, and the response to calcein addition and observed the secretion of newly formed sclerites. The BrdU tests showed that cell proliferation depends on the size of aggregates and on the presence/absence of symbiotic zooxanthellae. With epifluorescent and confocal imaging from calcein addition assays, we observed the presence of calcium ions within cells, a possible clue for prediction of sclerite formation or calcium deposition. The species-specific efficiency in production of cell aggregates is correlated to the size of polyps, showing that the higher density of polyps and their diameter correspond to higher production of cell aggregates. Regarding the long-term maintenance, we obtained the best results from E. singularis, which formed multicellular aggregates of 0.245 mm ± 0.086 mm in size and maintained symbiotic association with zooxanthellae throughout the experimental run. Formation of sclerites within aggregates opens a wide field of investigation on biomineralization, since de novo sclerites were observed around 30 d after the beginning of the experiment.

COMMERCIAL DEMONSTRATION OF THE MANUFACTURED AGGREGATE PROCESSING TECHNOLOGY UTILIZING SPRAY DRYER ASH

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roy Scandrol

2003-04-01

Universal Aggregates, LLC proposes to design, construct and operate a lightweight aggregate manufacturing plant at the Birchwood Power Facility in King George, Virginia. The installation and start-up expenses for the Birchwood Aggregate Facility are $19.5 million. The DOE share is $7.2 million (37%) and the Universal Aggregates share is $12.3 (63%). The project team consists of CONSOL Energy Inc., P.J. Dick, Inc., SynAggs, LLC, and Universal Aggregates, LLC. The Birchwood Facility will transform 115,000 tons per year of spray dryer by-products that are currently being disposed of in an offsite landfill into 167,000 tons of a useful product, lightweight aggregatesmore » that can be used to manufacture lightweight aggregates that can be used to manufacture lightweight and medium weight masonry blocks. In addition to the environmental benefits, the Birchwood Facility will create eight (8) manufacturing jobs plus additional employment in the local trucking industry to deliver the aggregate to customers or reagents to the facility. A successful demonstration would lead to additional lightweight aggregate manufacturing facilities in the United States. There are currently twenty-one (21) spray dryer facilities operating in the United States that produce an adequate amount of spray dryer by-product to economically justify the installation of a lightweight aggregate manufacturing facility. Industry sources believe that as additional scrubbing is required, dry flue gas desulfurization (FGD) technologies will be the technology of choice. Letters from potential lightweight aggregate customers indicate that there is a market for the product once the commercialization barriers are eliminated by this demonstration project.« less

Engineering a fibrocartilage spectrum through modulation of aggregate redifferentiation.

PubMed

Murphy, Meghan K; Masters, Taylor E; Hu, Jerry C; Athanasiou, Kyriacos A

2015-01-01

Expanded costochondral cells provide a clinically relevant cell source for engineering both fibrous and hyaline articular cartilage. Expanding chondrocytes in a monolayer results in a shift toward a proliferative, fibroblastic phenotype. Three-dimensional aggregate culture may, however, be used to recover chondrogenic matrix production. This study sought to engineer a spectrum of fibrous to hyaline neocartilage from a single cell source by varying the duration of three-dimensional culture following expansion. In third passage porcine costochondral cells, the effects of aggregate culture duration were assessed after 0, 8, 11, 14, and 21 days of aggregate culture and after 4 subsequent weeks of neocartilage formation. Varying the duration of aggregate redifferentiation generated a spectrum of fibrous to hyaline neocartilage. Within 8 days of aggregation, proliferation ceased, and collagen and glycosaminoglycan production increased, compared with monolayer cells. In self-assembled neocartilage, type II-to-I collagen ratio increased with increasing aggregate duration, yet glycosaminoglycan content varied minimally. Notably, 14 days of aggregate redifferentiation increased collagen content by 25%, tensile modulus by over 110%, and compressive moduli by over 50%, compared with tissue formed in the absence of redifferentiation. A spectrum of fibrous to hyaline cartilage was generated using a single, clinically relevant cell source, improving the translational potential of engineered cartilage.

Engineering a Fibrocartilage Spectrum Through Modulation of Aggregate Redifferentiation

PubMed Central

Murphy, Meghan K.; Masters, Taylor E.; Hu, Jerry C.; Athanasiou, Kyriacos A.

2015-01-01

Expanded costochondral cells provide a clinically relevant cell source for engineering both fibrous and hyaline articular cartilage. Expanding chondrocytes in monolayer results in a shift toward a proliferative, fibroblastic phenotype. Three-dimensional aggregate culture may, however, be used to recover chondrogenic matrix production. This study sought to engineer a spectrum of fibrous to hyaline neocartilage from a single cell source by varying the duration of three-dimensional culture following expansion. In third passage porcine costochondral cells, the effects of aggregate culture duration were assessed after 0, 8, 11, 14, and 21 days of aggregate culture and after 4 subsequent weeks of neocartilage formation. Varying the duration of aggregate redifferentiation generated a spectrum of fibrous to hyaline neocartilage. Within 8 days of aggregation, proliferation ceased, and collagen and glycosaminoglycan production increased, compared with monolayer cells. In self-assembled neocartilage, type II to I collagen ratio increased with increasing aggregate duration, yet glycosaminoglycan content varied minimally. Notably, 14 days of aggregate redifferentiation increased collagen content by 25%, tensile modulus by over 110%, and compressive moduli by over 50%, compared with tissue formed in the absence of redifferentiation. A spectrum of fibrous to hyaline cartilage was generated using a single, clinically relevant cell source, improving the translational potential of engineered cartilage. PMID:24380383

Lightweight alumina refractory aggregate. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Swansiger, T.G.; Pearson, A.

1996-07-16

Objective was to develop a lightweight, high alumina refractory aggregate for use in various high performance insulating (low thermal conductivity) refractory applications (e.g., in the aluminium, glass, cement, and iron and steel industries). A new aggregate process was developed through bench and pilot-scale experiments involving extrusion of a blend of calcined and activated alumina powders and organic extrusion aids and binders. The aggregate, with a bulk density approaching 2.5 g/cc, exhibited reduced thermal conductivity and adequate fired strength compared to dense tabular aggregate. Refractory manufacturers were moderately enthusiastic over the results. Alcoa prepared an economic analysis for producing lightweight aggregate,more » based on a retrofit of this process into existing Alcoa production facilities. However, a new, competing lightweight aggregate material was developed by another company; this material (Plasmal{trademark})had a significantly more favorable cost base than the Alcoa/DOE material, due to cheap raw materials and fewer processing steps. In late 1995, Alcoa became a distributor of Plasmal. Alcoa estimated that {ge}75% of the market originally envisioned for the Alcoa/DOE aggregate would be taken by Plasmal. Hence, it was decided to terminate the contract without the full- scale demonstration.« less

Fluorescence dye-based detection of mAb aggregates in CHO culture supernatants.

PubMed

Paul, Albert Jesuran; Schwab, Karen; Prokoph, Nina; Haas, Elena; Handrick, René; Hesse, Friedemann

2015-06-01

Product yields, efficacy, and safety of monoclonal antibodies (mAbs) are reduced by the formation of higher molecular weight aggregates during upstream processing. In-process characterization of mAb aggregate formation is a challenge since there is a lack of a fast detection method to identify mAb aggregates in cell culture. In this work, we present a rapid method to characterize mAb aggregate-containing Chinese hamster ovary (CHO) cell culture supernatants. The fluorescence dyes thioflavin T (ThT) and 4-4-bis-1-phenylamino-8-naphthalene sulfonate (Bis-ANS) enabled the detection of soluble as well as large mAb aggregates. Partial least square (PLS) regression models were used to evaluate the linearity of the dye-based mAb aggregate detection in buffer down to a mAb aggregate concentration of 2.4 μg mL(-1). Furthermore, mAb aggregates were detected in bioprocess medium using Bis-ANS and ThT. Dye binding to aggregates was stable for 60 min, making the method robust and reliable. Finally, the developed method using 10 μmol L(-1) Bis-ANS enabled discrimination between CHO cell culture supernatants containing different levels of mAb aggregates. The method can be adapted for high-throughput screening, e.g., to screen for cell culture conditions influencing mAb product quality, and hence can contribute to the improvement of production processes of biopharmaceuticals in mammalian cell culture.

Physio-chemical reactions in recycle aggregate concrete.

PubMed

Tam, Vivian W Y; Gao, X F; Tam, C M; Ng, K M

2009-04-30

Concrete waste constitutes the major proportion of construction waste at about 50% of the total waste generated. An effective way to reduce concrete waste is to reuse it as recycled aggregate (RA) for the production of recycled aggregate concrete (RAC). This paper studies the physio-chemical reactions of cement paste around aggregate for normal aggregate concrete (NAC) and RAC mixed with normal mixing approach (NMA) and two-stage mixing approach (TSMA) by differential scanning calorimetry (DSC) and scanning electron microscopy (SEM). Four kinds of physio-chemical reactions have been recorded from the concrete samples, including the dehydration of C(3)S(2)H(3), iron-substituted ettringite, dehydroxylation of CH and development of C(6)S(3)H at about 90 degrees C, 135 degrees C, 441 degrees C and 570 degrees C, respectively. From the DSC results, it is confirmed that the concrete samples with RA substitution have generated less amount of strength enhancement chemical products when compared to those without RA substitution. However, the results from the TSMA are found improving the RAC quality. The pre-mix procedure of the TSMA can effectively develop some strength enhancing chemical products including, C(3)S(2)H(3), ettringite, CH and C(6)S(3)H, which shows that RAC made from the TSMA can improve the hydration processes.

76 FR 56322 - Atlantic Surfclam and Ocean Quahog Fisheries; 2012 Fishing Quotas for Atlantic Surfclams and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-13

.... 101013504-0610-02] RIN 0648-XA529 Atlantic Surfclam and Ocean Quahog Fisheries; 2012 Fishing Quotas for.... ACTION: Temporary rule. SUMMARY: NMFS suspends the minimum size limit for Atlantic surfclams for the 2012... 2012 will remain status quo. Regulations governing these fisheries require NMFS to notify the public in...

Combined research effort on aggregate road materials

NASA Astrophysics Data System (ADS)

Kuznetsova, Elena; Hoff, Inge; Willy Danielsen, Svein; Wigum, Børge Johannes; Fladvad, Marit; Rieksts, Karlis; Loranger, Benoit; Barbieri, Diego

2017-04-01

In European countries, the average aggregate consumption per capita is 5 tons per year (European Aggregates Association 2016), while the corresponding number in Norway is 11 tons (Neeb 2015). Due to the increased demand for sand and gravel for construction purposes, e.g. in road construction, the last decade has seen a significant trend towards the use of crushed rock aggregates. Neeb (2015) reports that half of the Norwegian aggregate production (sand, gravel and crushed rock) is used for road construction, and 33 % of the overall sold tonnage of crushed rock is exported. This resource has been more and more preferred over sand and gravel due to the significant technological development of its process and utilization phase. In Norway, the development and implementation of crushed aggregate technology has been the main approach to solve natural resource scarcity (Danielsen and Kuznetsova 2015). In order to reduce aggregates transportation, it is aimed to use local aggregates and aggregates processed from rock excavations, tunneling, road cuts, etc. One issue focused in this research is the influence from blasting and processing on the final quality of the crushed aggregates, specifically relating to the properties for road construction purposes. It is therefor crucial to plan utilization of available materials for use in different road layers following the same production line. New developments and improved availability of mobile crushing and screening equipment could produce more sustainable and profitable sources of good quality aggregate materials from small volume deposits in proximity to construction sites. One of the biggest challenges today to use these materials is that the pavement design manual sets rigid requirements for pavement layers. Four research projects are being conducted in Norway to improve the use of local materials for road construction. Four aspects are to be covered by the research: a) geological characteristics of the materials, their b

78 FR 59917 - Limitations of Duty- and Quota-Free Imports of Apparel Articles Assembled in Beneficiary Sub...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-30

... of Apparel Articles Assembled in Beneficiary Sub-Saharan African Countries From Regional and Third... quota-free treatment for certain textile and apparel articles imported from designated beneficiary sub... apparel articles wholly assembled in one or more beneficiary sub-Saharan African countries from fabric...

75 FR 60066 - Limitations of Duty- and Quota-Free Imports of Apparel Articles Assembled in Beneficiary ATPDEA...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-29

... of Apparel Articles Assembled in Beneficiary ATPDEA Countries From Regional Country Fabric AGENCY... (ATPA) to provide for duty and quota-free treatment for certain textile and apparel articles imported... articles assembled in ATPDEA beneficiary countries from regional fabric and components. More specifically...

76 FR 1137 - Amendment of Limitation of Duty- and Quota-Free Imports of Apparel Articles Assembled in...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-07

... COMMITTEE FOR THE IMPLEMENTATION OF TEXTILE AGREEMENTS Amendment of Limitation of Duty- and Quota-Free Imports of Apparel Articles Assembled in Beneficiary ATPDEA Countries From Regional Country Fabric AGENCY: Committee for the Implementation of Textile Agreements (CITA). ACTION: Amending the 12-Month Cap...

76 FR 66915 - Amendment of Limitation of Duty- and Quota-Free Imports of Apparel Articles Assembled in...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-28

... COMMITTEE FOR THE IMPLEMENTATION OF TEXTILE AGREEMENTS Amendment of Limitation of Duty- and Quota-Free Imports of Apparel Articles Assembled in Beneficiary ATPDEA Countries From Regional Country Fabric AGENCY: Committee for the Implementation of Textile Agreements (CITA). ACTION: Amending the 12-Month Cap...

77 FR 59913 - Amendment of Limitation of Duty- and Quota-Free Imports of Apparel Articles Assembled in...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-01

... COMMITTEE FOR THE IMPLEMENTATION OF TEXTILE AGREEMENTS Amendment of Limitation of Duty- and Quota-Free Imports of Apparel Articles Assembled in Beneficiary ATPDEA Countries From Regional Country Fabric AGENCY: Committee for the Implementation of Textile Agreements (CITA). ACTION: Amending the 12-month cap...

Construction aggregates

USGS Publications Warehouse

Tepordei, V.V.

1993-01-01

Part of a special section on the market performance of industrial minerals in 1992. Production of construction aggregates increased by 4.6 percent in 1992. This increase was due, in part, to the increased funding for transportation and infrastructure projects. The U.S. produced about 1.05 Gt of crushed stone and an estimated 734 Mt of construction sand and gravel in 1992. Demand is expected to increase by about 5 percent in 1993.

Continuum-level modelling of cellular adhesion and matrix production in aggregates.

PubMed

Geris, Liesbet; Ashbourn, Joanna M A; Clarke, Tim

2011-05-01

Key regulators in tissue-engineering processes such as cell culture and cellular organisation are the cell-cell and cell-matrix interactions. As mathematical models are increasingly applied to investigate biological phenomena in the biomedical field, it is important, for some applications, that these models incorporate an adequate description of cell adhesion. This study describes the development of a continuum model that represents a cell-in-gel culture system used in bone-tissue engineering, namely that of a cell aggregate embedded in a hydrogel. Cell adhesion is modelled through the use of non-local (integral) terms in the partial differential equations. The simulation results demonstrate that the effects of cell-cell and cell-matrix adhesion are particularly important for the survival and growth of the cell population and the production of extracellular matrix by the cells, concurring with experimental observations in the literature.

77 FR 65136 - Fisheries of the Northeastern United States; Black Sea Bass Fishery; Recreational Quota Harvested

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-25

... fishing commercially. Regulations governing the black sea bass fishery require publication of this... no Federal recreational quota is available for fishing black sea bass. DATES: Effective at 0001 hr.... The initial total RHL for black sea bass for the 2012 fishing year is 1.86 million lb (844 mt) (76 FR...

Aggregation of a Monoclonal Antibody Induced by Adsorption to Stainless Steel

PubMed Central

Bee, Jared S.; Davis, Michele; Freund, Erwin; Carpenter, John F.; Randolph, Theodore W.

2014-01-01

Stainless steel is a ubiquitous surface in therapeutic protein production equipment and is also present as the needle in some pre-filled syringe biopharmaceutical products. Stainless steel microparticles can cause of aggregation of a monoclonal antibody (mAb). The initial rate of mAb aggregation was second-order in steel surface area and zero-order in mAb concentration, generally consistent with a bimolecular surface aggregation being the rate-limiting step. Polysorbate 20 (PS20) suppressed the aggregation yet was unable to desorb the firmly bound first layer of protein that adsorbs to the stainless steel surface. Also, there was no exchange of mAb from the first adsorbed layer to the bulk phase, suggesting that the aggregation process actually occurs on subsequent adsorption layers. No oxidized Met residues were detected in the mass spectrum of a digest of a highly aggregated mAb, although there was five-fold increase in carbonyl groups due to protein oxidation. PMID:19725039

Dissociation and Re-Aggregation of Multicell-Ensheathed Fragments Responsible for Rapid Production of Massive Clumps of Leptothrix Sheaths

PubMed Central

Kunoh, Tatsuki; Nagaoka, Noriyuki; McFarlane, Ian R.; Tamura, Katsunori; El-Naggar, Mohamed Y.; Kunoh, Hitoshi; Takada, Jun

2016-01-01

Species of the Fe/Mn-oxidizing bacteria Leptothrix produce tremendous amounts of microtubular, Fe/Mn-encrusted sheaths within a few days in outwells of groundwater that can rapidly clog water systems. To understand this mode of rapid sheath production and define the timescales involved, behaviors of sheath-forming Leptothrix sp. strain OUMS1 were examined using time-lapse video at the initial stage of sheath formation. OUMS1 formed clumps of tangled sheaths. Electron microscopy confirmed the presence of a thin layer of bacterial exopolymer fibrils around catenulate cells (corresponding to the immature sheath). In time-lapse videos, numerous sheath filaments that extended from the periphery of sheath clumps repeatedly fragmented at the apex of the same fragment, the fragments then aggregated and again elongated, eventually forming a large sheath clump comprising tangled sheaths within two days. In this study, we found that fast microscopic fragmentation, dissociation, re-aggregation and re-elongation events are the basis of the rapid, massive production of Leptothrix sheaths typically observed at macroscopic scales. PMID:27490579

Application of Recycled Ceramic Aggregates for the Production of Mineral-Asphalt Mixtures.

PubMed

Andrzejuk, Wojciech; Barnat-Hunek, Danuta; Siddique, Rafat; Zegardło, Bartosz; Łagód, Grzegorz

2018-04-24

This paper describes a method of designing and producing innovative mineral⁻asphalt mixtures, which utilize waste aggregate from the recycling of sanitary ceramics. The work presents the basic properties of the ceramic material, the investigation concerning the microstructure of the aggregate obtained from the grinding of waste, and a comparison with the images obtained for the aggregates usually employed in mineral⁻asphalt mixtures. The mixtures were designed for the application in the wearing course. Four series of mixtures were prepared. In the first and second, the ceramic aggregate constituted a partial substitute for dolomite, whereas in the third, we substituted granodiorite, and the fourth series contained only dolomite. The mixtures were examined for the content of soluble binder, the bulk density of samples, the presence of voids, the space filled with binder, and the susceptibility to water and frost corrosion. The obtained results were compared with the standard requirements. The microstructure as well as the contact zone in the considered mineral⁻asphalt mixtures are presented based on research conducted by means of a scanning electron microscope (SEM).

Application of Recycled Ceramic Aggregates for the Production of Mineral-Asphalt Mixtures

PubMed Central

Andrzejuk, Wojciech; Barnat-Hunek, Danuta; Siddique, Rafat; Zegardło, Bartosz; Łagód, Grzegorz

2018-01-01

This paper describes a method of designing and producing innovative mineral–asphalt mixtures, which utilize waste aggregate from the recycling of sanitary ceramics. The work presents the basic properties of the ceramic material, the investigation concerning the microstructure of the aggregate obtained from the grinding of waste, and a comparison with the images obtained for the aggregates usually employed in mineral–asphalt mixtures. The mixtures were designed for the application in the wearing course. Four series of mixtures were prepared. In the first and second, the ceramic aggregate constituted a partial substitute for dolomite, whereas in the third, we substituted granodiorite, and the fourth series contained only dolomite. The mixtures were examined for the content of soluble binder, the bulk density of samples, the presence of voids, the space filled with binder, and the susceptibility to water and frost corrosion. The obtained results were compared with the standard requirements. The microstructure as well as the contact zone in the considered mineral–asphalt mixtures are presented based on research conducted by means of a scanning electron microscope (SEM). PMID:29695115

Effect of settled diatom‐aggregates on benthic nitrogen cycling

PubMed Central

Thamdrup, Bo; Stief, Peter; Glud, Ronnie N.

2017-01-01

Abstract The marine sediment hosts a mosaic of microhabitats. Recently it has been demonstrated that the settlement of phycodetrital aggregates can induce local changes in the benthic O2 distribution due to confined enrichment of organic material and alteration of the diffusional transport. Here, we show how this microscale O2 shift substantially affects benthic nitrogen cycling. In sediment incubations, the settlement of diatom‐aggregates markedly enhanced benthic O2 and NO3− consumption and stimulated NO2− and NH4+ production. Oxygen microprofiles revealed the rapid development of anoxic niches within and underneath the aggregates. During 120 h following the settling of the aggregates, denitrification of NO3− from the overlying water increased from 13.5 μmol m−2 h−1 to 24.3 μmol m−2 h−1, as quantified by 15N enrichment experiment. Simultaneously, N2 production from coupled nitrification‐denitrification decreased from 33.4 μmol m−2 h−1 to 25.9 μmol m−2 h−1, probably due to temporary inhibition of the benthic nitrifying community. The two effects were of similar magnitude and left the total N2 production almost unaltered. At the aggregate surface, nitrification was, conversely, very efficient in oxidizing NH4+ liberated by mineralization of the aggregates. The produced NO3− was preferentially released into the overlying water and only a minor fraction contributed to denitrification activity. Overall, our data indicate that the abrupt change in O2 microdistribution caused by aggregates stimulates denitrification of NO3− from the overlying water, and loosens the coupling between benthic nitrification and denitrification both in time and space. The study contributes to expanding the conceptual and quantitative understanding of how nitrogen cycling is regulated in dynamic benthic environments. PMID:29456269

Environmentalism and natural aggregate mining

USGS Publications Warehouse

Drew, L.J.; Langer, W.H.; Sachs, J.S.

2002-01-01

living space has encroached on the sites of production; in other words, the act of production has engendered condemnation. Many other environmental problems that are associated with dust and noise and blasting from quarry and pit operations have been reduced through the efficient use of technology. Recycling concrete in buildings, bridges, and roads and asphaltic pavements will ultimately reduce the demand for virgin natural aggregate. The impact created by the large holes in the ground required for the mining of natural aggregate can be greatly reduced by planning their reclamation before mining begins. ?? 2002 International Association for Mathematical Geology.

Strength of masonry blocks made with recycled concrete aggregates

NASA Astrophysics Data System (ADS)

Matar, Pierre; Dalati, Rouba El

The idea of recycling concrete of demolished buildings aims at preserving the environment. Indeed, the reuse of concrete as aggregate in new concrete mixes helped to reduce the expenses related to construction and demolition (C&D) waste management and, especially, to protect the environment by reducing the development rate of new quarries. This paper presents the results of an experimental study conducted on masonry blocks containing aggregates resulting from concrete recycling. The purpose of this study is to investigate the effect of recycled aggregates on compressive strength of concrete blocks. Tests were performed on series of concrete blocks: five series each made of different proportions of recycled aggregates, and one series of reference blocks exclusively composed of natural aggregates. Tests showed that using recycled aggregates with addition of cement allows the production of concrete blocks with compressive strengths comparable to those obtained on concrete blocks made exclusively of natural aggregates.

49 CFR 23.61 - Can recipients use quotas or set-asides as part of their ACDBE programs?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 1 2013-10-01 2013-10-01 false Can recipients use quotas or set-asides as part of their ACDBE programs? 23.61 Section 23.61 Transportation Office of the Secretary of Transportation PARTICIPATION OF DISADVANTAGED BUSINESS ENTERPRISE IN AIRPORT CONCESSIONS Goals, Good Faith Efforts, and...

49 CFR 23.61 - Can recipients use quotas or set-asides as part of their ACDBE programs?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 1 2011-10-01 2011-10-01 false Can recipients use quotas or set-asides as part of their ACDBE programs? 23.61 Section 23.61 Transportation Office of the Secretary of Transportation PARTICIPATION OF DISADVANTAGED BUSINESS ENTERPRISE IN AIRPORT CONCESSIONS Goals, Good Faith Efforts, and...

49 CFR 23.61 - Can recipients use quotas or set-asides as part of their ACDBE programs?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 1 2014-10-01 2014-10-01 false Can recipients use quotas or set-asides as part of their ACDBE programs? 23.61 Section 23.61 Transportation Office of the Secretary of Transportation PARTICIPATION OF DISADVANTAGED BUSINESS ENTERPRISE IN AIRPORT CONCESSIONS Goals, Good Faith Efforts, and...

49 CFR 23.61 - Can recipients use quotas or set-asides as part of their ACDBE programs?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 1 2012-10-01 2012-10-01 false Can recipients use quotas or set-asides as part of their ACDBE programs? 23.61 Section 23.61 Transportation Office of the Secretary of Transportation PARTICIPATION OF DISADVANTAGED BUSINESS ENTERPRISE IN AIRPORT CONCESSIONS Goals, Good Faith Efforts, and...

49 CFR 23.61 - Can recipients use quotas or set-asides as part of their ACDBE programs?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false Can recipients use quotas or set-asides as part of their ACDBE programs? 23.61 Section 23.61 Transportation Office of the Secretary of Transportation PARTICIPATION OF DISADVANTAGED BUSINESS ENTERPRISE IN AIRPORT CONCESSIONS Goals, Good Faith Efforts, and...

Sustainable aggregate production planning in the chemical process industry - A benchmark problem and dataset.

PubMed

Brandenburg, Marcus; Hahn, Gerd J

2018-06-01

Process industries typically involve complex manufacturing operations and thus require adequate decision support for aggregate production planning (APP). The need for powerful and efficient approaches to solve complex APP problems persists. Problem-specific solution approaches are advantageous compared to standardized approaches that are designed to provide basic decision support for a broad range of planning problems but inadequate to optimize under consideration of specific settings. This in turn calls for methods to compare different approaches regarding their computational performance and solution quality. In this paper, we present a benchmarking problem for APP in the chemical process industry. The presented problem focuses on (i) sustainable operations planning involving multiple alternative production modes/routings with specific production-related carbon emission and the social dimension of varying operating rates and (ii) integrated campaign planning with production mix/volume on the operational level. The mutual trade-offs between economic, environmental and social factors can be considered as externalized factors (production-related carbon emission and overtime working hours) as well as internalized ones (resulting costs). We provide data for all problem parameters in addition to a detailed verbal problem statement. We refer to Hahn and Brandenburg [1] for a first numerical analysis based on and for future research perspectives arising from this benchmarking problem.

Lactobacillus rhamnosus GG (ATCC 53103) and platelet aggregation in vitro.

PubMed

Korpela, R; Moilanen, E; Saxelin, M; Vapaatalo, H

1997-06-17

Lactobacillus rhamnosus GG is an experimentally and clinically well documented probiotic used in different dairy products. The present study aimed to investigate the safety aspects of Lactobacillus rhamnosus GG, particularly with respect to platelet aggregation, the initiating event in thrombosis. Platelet rich plasma was separated from the blood of healthy volunteers, and the effects of Lactobacillus rhamnosus GG (ATCC 53103), Lactobacillus rhamnosus (ATCC 7469) and Enterococcus faecium T2L6 in different dilutions on spontaneous, ADP- and adrenaline-induced aggregation were tested. The bacteria did not influence spontaneous aggregation. Only Enterococcus faecium T2L6 enhanced the adrenaline-induced aggregation, with a less clear effect on ADP-induced aggregation.

Enhanced DNA Sensing via Catalytic Aggregation of Gold Nanoparticles

PubMed Central

Huttanus, Herbert M.; Graugnard, Elton; Yurke, Bernard; Knowlton, William B.; Kuang, Wan; Hughes, William L.; Lee, Jeunghoon

2014-01-01

A catalytic colorimetric detection scheme that incorporates a DNA-based hybridization chain reaction into gold nanoparticles was designed and tested. While direct aggregation forms an inter-particle linkage from only ones target DNA strand, the catalytic aggregation forms multiple linkages from a single target DNA strand. Gold nanoparticles were functionalized with thiol-modified DNA strands capable of undergoing hybridization chain reactions. The changes in their absorption spectra were measured at different times and target concentrations and compared against direct aggregation. Catalytic aggregation showed a multifold increase in sensitivity at low target concentrations when compared to direct aggregation. Gel electrophoresis was performed to compare DNA hybridization reactions in catalytic and direct aggregation schemes, and the product formation was confirmed in the catalytic aggregation scheme at low levels of target concentrations. The catalytic aggregation scheme also showed high target specificity. This application of a DNA reaction network to gold nanoparticle-based colorimetric detection enables highly-sensitive, field-deployable, colorimetric readout systems capable of detecting a variety of biomolecules. PMID:23891867

Prediction and Reduction of the Aggregation of Monoclonal Antibodies.

PubMed

van der Kant, Rob; Karow-Zwick, Anne R; Van Durme, Joost; Blech, Michaela; Gallardo, Rodrigo; Seeliger, Daniel; Aßfalg, Kerstin; Baatsen, Pieter; Compernolle, Griet; Gils, Ann; Studts, Joey M; Schulz, Patrick; Garidel, Patrick; Schymkowitz, Joost; Rousseau, Frederic

2017-04-21

Protein aggregation remains a major area of focus in the production of monoclonal antibodies. Improving the intrinsic properties of antibodies can improve manufacturability, attrition rates, safety, formulation, titers, immunogenicity, and solubility. Here, we explore the potential of predicting and reducing the aggregation propensity of monoclonal antibodies, based on the identification of aggregation-prone regions and their contribution to the thermodynamic stability of the protein. Although aggregation-prone regions are thought to occur in the antigen binding region to drive hydrophobic binding with antigen, we were able to rationally design variants that display a marked decrease in aggregation propensity while retaining antigen binding through the introduction of artificial aggregation gatekeeper residues. The reduction in aggregation propensity was accompanied by an increase in expression titer, showing that reducing protein aggregation is beneficial throughout the development process. The data presented show that this approach can significantly reduce liabilities in novel therapeutic antibodies and proteins, leading to a more efficient path to clinical studies. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

75 FR 26316 - Allocation of Additional Fiscal Year (FY) 2010 In-Quota Volume for Raw Cane Sugar

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-11

...-Quota Volume for Raw Cane Sugar AGENCY: Office of the United States Trade Representative. ACTION: Notice...) for imported raw cane sugar. DATES: Effective Date: May 11, 2010. ADDRESSES: Inquiries may be mailed... (HTS), the United States maintains TRQs for imports of raw cane and refined sugar. Section 404(d)(3) of...

75 FR 14479 - Reallocation of Unused Fiscal Year 2010 Tariff-Rate Quota Volume for Raw Cane Sugar

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-25

...-Rate Quota Volume for Raw Cane Sugar AGENCY: Office of the United States Trade Representative. ACTION... (TRQ) for imported raw cane sugar. DATES: Effective Date: March 25, 2010. ADDRESSES: Inquiries may be... (HTS), the United States maintains TRQs for imports of raw cane and refined sugar. Section 404(d)(3) of...

An aggregate analysis of personal care products in the environment: Identifying the distribution of environmentally-relevant concentrations.

PubMed

Hopkins, Zachary R; Blaney, Lee

2016-01-01

Over the past 3-4 decades, per capita consumption of personal care products (PCPs) has steadily risen, resulting in increased discharge of the active and inactive ingredients present in these products into wastewater collection systems. PCPs comprise a long list of compounds employed in toothpaste, sunscreen, lotions, soaps, body washes, and insect repellants, among others. While comprehensive toxicological studies are not yet available, an increasing body of literature has shown that PCPs of all classes can impact aquatic wildlife, bacteria, and/or mammalian cells at low concentrations. Ongoing research efforts have identified PCPs in a variety of environmental compartments, including raw wastewater, wastewater effluent, surface water, wastewater solids, sediment, groundwater, and drinking water. Here, an aggregate analysis of over 5000 reported detections was conducted to better understand the distribution of environmentally-relevant PCP concentrations in, and between, these compartments. The distributions were used to identify whether aggregated environmentally-relevant concentration ranges intersected with available toxicity data. For raw wastewater, wastewater effluent, and surface water, a clear overlap was present between the 25th-75th percentiles and identified toxicity levels. This analysis suggests that improved wastewater treatment of antimicrobials, UV filters, and polycyclic musks is required to prevent negative impacts on aquatic species. Copyright © 2016 Elsevier Ltd. All rights reserved.

Reusing recycled aggregates in structural concrete

NASA Astrophysics Data System (ADS)

Kou, Shicong

results, a number of recommendations were made on how to optimize the use of recycled aggregates for structural concrete production. The results demonstrate that one of the practical ways to utilize a higher percentage of recycled aggregates in concrete is "precasting" with the use of fly ash and an initial steam curing stage immediately after casting.

Modulation of platelet aggregation by areca nut and betel leaf ingredients: roles of reactive oxygen species and cyclooxygenase.

PubMed

Jeng, Jiiang-Huei; Chen, Shiao-Yun; Liao, Chang-Hui; Tung, Yuan-Yii; Lin, Bor-Ru; Hahn, Liang-Jiunn; Chang, Mei-Chi

2002-05-01

There are 2 to 6 billion betel quid (BQ) chewers in the world. Areca nut (AN), a BQ component, modulates arachidonic acid (AA) metabolism, which is crucial for platelet function. AN extract (1 and 2 mg/ml) stimulated rabbit platelet aggregation, with induction of thromboxane B2 (TXB2) production. Contrastingly, Piper betle leaf (PBL) extract inhibited AA-, collagen-, and U46619-induced platelet aggregation, and TXB2 and prostaglandin-D2 (PGD2) production. PBL extract also inhibited platelet TXB2 and PGD2 production triggered by thrombin, platelet activating factor (PAF), and adenosine diphosphate (ADP), whereas little effect on platelet aggregation was noted. Moreover, PBL is a scavenger of O2(*-) and *OH, and inhibits xanthine oxidase activity and the (*)OH-induced PUC18 DNA breaks. Deferoxamine, 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA) and neomycin prevented AN-induced platelet aggregation and TXB2 production. Indomethacin, genistein, and PBL extract inhibited only TXB2 production, but not platelet aggregation. Catalase, superoxide dismutase, and dimethylthiourea (DMT) showed little effect on AN-induced platelet aggregation, whereas catalase and DMT inhibited the AN-induced TXB2 production. These results suggest that AN-induced platelet aggregation is associated with iron-mediated reactive oxygen species production, calcium mobilization, phospholipase C activation, and TXB2 production. PBL inhibited platelet aggregation via both its antioxidative effects and effects on TXB2 and PGD2 production. Effects of AN and PBL on platelet aggregation and AA metabolism is crucial for platelet activation in the oral mucosa and cardiovascular system in BQ chewers.

78 FR 5775 - Notice of Allocation of Tariff Rate Quotas (TRQ) on the Import of Certain Worsted Wool Fabrics...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-28

... DEPARTMENT OF COMMERCE International Trade Administration Notice of Allocation of Tariff Rate... Trade Administration, Department of Commerce. ACTION: Notice of allocation of 2013 worsted wool fabric tariff rate quota. SUMMARY: The Department of Commerce (Department) has determined the allocation for...

Estimating the Costs to Consumers of the U.S. Sugar Quota: An Exercise for Introductory Economics Classes.

ERIC Educational Resources Information Center

Williams, Andrew T.

1997-01-01

Provides a classroom exercise using the restrictive tariffs on sugar to examine issues of protectionism and international trade. Discusses related issues such as the North American Free Trade Agreement and the formation of large regional trading blocks. Includes a hands-on calculation of the economic impact of the quota on consumers. (MJP)

77 FR 59913 - Limitations of Duty- and Quota-Free Imports of Apparel Articles Assembled in Beneficiary Sub...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-01

... the new 12-month cap on duty- and quota-free benefits. DATES: Effective October 1, 2012. FOR FURTHER INFORMATION CONTACT: Don Niewiaroski, Jr., International Trade Specialist, Office of Textiles and Apparel, U.S... the Trade and Development Act of 2000 (TDA 2000), Public Law 106-200, as amended by Division B, Title...

76 FR 59663 - Limitations of Duty- and Quota-Free Imports of Apparel Articles Assembled in Beneficiary Sub...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-27

... of Apparel Articles Assembled in Beneficiary Sub-Saharan African Countries From Regional and Third... Acceleration Act of 2004, Pub. L. 108-274; Division D, Title VI, section 6002 of the Tax Relief and Health Care... beneficiary sub-Saharan African countries. Section 112(b)(3) of TDA 2000 provides duty- and quota-free...

Nontronite Particle Aggregation Induced by Microbial Fe(III) Reduction and Exopolysaccharide Production

DTIC Science & Technology

2007-01-01

polymers to achieve desired properties (such Chenu el al., 1979; Kimn el al., 2005). Among these as aggregation. dispersion ) without any structural...performed with and without Na pyrophosphate as a term ’aggregation’ broadly to include all processes that dispersant (25 mM) with shaking in a water...coagulation, at 25 mM was found to be optimal to disperse individual flocculation, agglutination, etc.). The results of this clay particles without

Reduction in soil aggregate size distribution due to wind erosion

NASA Astrophysics Data System (ADS)

Swet, Nitzan; Katra, Itzhak

2017-04-01

Soil erosion process by wind causes emission of fine soil particles, and thus alters the topsoil's properties, fertility, and erodibility. Topsoil resistance to erosion depends on its physicochemical properties, especially on the soil aggregation. Although the key role of aggregates in soil erodibility, quantitative information on the relations between soil aggregate size distribution (ASD) and erosion is still lucking. This study focuses on ASD analyses before and after soil erosion by wind. Wind tunnel experiments and soil analyses were conducted on semiarid loess topsoils with different initial conditions of aggregation. The results show that in all initial soil conditions saltation of sand particles caused the breakdown of macro-aggregates > 500 µm, resulting in increase of micro-aggregates (63-250 µm). The micro-aggregate production increases with the wind shear velocity (up to 0.61 m s-1) for soils with available macro-aggregates. The findings highlight dynamics in soil aggregation in response to erosion process, and therefore the significance of ASD in quantifying soil degradation and soil loss potential.

Challenges for simultaneous nitrification, denitrification, and phosphorus removal in microbial aggregates: mass transfer limitation and nitrous oxide production.

PubMed

Meyer, Rikke Louise; Zeng, Raymond Jianxiong; Giugliano, Valerio; Blackall, Linda Louise

2005-05-01

The microbial community composition and activity was investigated in aggregates from a lab-scale bioreactor, in which nitrification, denitrification and phosphorus removal occurred simultaneously. The biomass was highly enriched for polyphosphate accumulating organisms facilitating complete removal of phosphorus from the bulk liquid; however, some inorganic nitrogen still remained at the end of the reactor cycle. This was ascribed to incomplete coupling of nitrification and denitrification causing NO(3)(-) accumulation. After 2 h of aeration, denitrification was dependent on the activity of nitrifying bacteria facilitating the formation of anoxic zones in the aggregates; hence, denitrification could not occur without simultaneous nitrification towards the end of the reactor cycle. Nitrous oxide was identified as a product of denitrification, when based on stored PHA as carbon source. This observation is of critical importance to the outlook of applying PHA-driven denitrification in activated sludge processes.

76 FR 42160 - Allocation of Additional Fiscal Year (FY) 2011 In-Quota Volume for Raw Cane Sugar

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-18

...-Quota Volume for Raw Cane Sugar AGENCY: Office of the United States Trade Representative. ACTION: Notice...) for imported raw cane sugar. USTR is also reallocating a portion of the unused original FY 2011 TRQ... imports of raw cane and refined sugar. Section 404(d)(3) of the Uruguay Round Agreements Act (19 U.S.C...

7 CFR 718.206 - Determining farms, tracts, allotments, quotas, and bases when reconstitution is made by division.

Code of Federal Regulations, 2010 CFR

2010-01-01

.... (b)(1) The estate method is the pro-rata distribution of allotments, quotas, and bases for a parent... ownership of a tract of land is transferred from a parent farm, the transferring owner may request that the... double cropped, between the parent farm and the transferred tract, or between the various tracts if the...

75 FR 54290 - Fisheries of the Northeastern United States; Scup Fishery; Adjustment to the 2010 Winter II Quota

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-07

... (Framework 3) to the Summer Flounder, Scup, and Black Sea Bass Fishery Management Plan, which established a process to allow the rollover of unused commercial scup quota from the Winter I period to the Winter II...: Sarah Heil, Fishery Management Specialist, (978) 281-9257. SUPPLEMENTARY INFORMATION: NMFS published a...

75 FR 22418 - The Tariff-Rate Quota for Calendar Year 2010 Tuna Classifiable Under Subheading 1604.14.22...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-28

... Security. ACTION: Announcement of the quota quantity of tuna in airtight containers for Calendar Year 2010... the apparent United States consumption of tuna in airtight containers during the preceding Calendar... been determined that 16,618,716 kilograms of tuna in air- tight containers may be entered and withdrawn...

IL-18 associated with lung lymphoid aggregates drives IFNγ production in severe COPD.

PubMed

Briend, Emmanuel; Ferguson, G John; Mori, Michiko; Damera, Gautam; Stephenson, Katherine; Karp, Natasha A; Sethi, Sanjay; Ward, Christine K; Sleeman, Matthew A; Erjefält, Jonas S; Finch, Donna K

2017-08-22

Increased interferon gamma (IFNγ) release occurs in Chronic Obstructive Pulmonary Disease (COPD) lungs. IFNγ supports optimal viral clearance, but if dysregulated could increase lung tissue destruction. The present study investigates which mediators most closely correlate with IFNγ in sputum in stable and exacerbating disease, and seeks to shed light on the spatial requirements for innate production of IFNγ, as reported in mouse lymph nodes, to observe whether such microenvironmental cellular organisation is relevant to IFNγ production in COPD lung. We show tertiary follicle formation in severe disease alters the dominant mechanistic drivers of IFNγ production, because cells producing interleukin-18, a key regulator of IFNγ, are highly associated with such structures. Interleukin-1 family cytokines correlated with IFNγ in COPD sputum. We observed that the primary source of IL-18 in COPD lungs was myeloid cells within lymphoid aggregates and IL-18 was increased in severe disease. IL-18 released from infected epithelium or from activated myeloid cells, was more dominant in driving IFNγ when IL-18-producing and responder cells were in close proximity. Unlike tight regulation to control infection spread in lymphoid organs, this local interface between IL-18-expressing and responder cell is increasingly supported in lung as disease progresses, increasing its potential to increase tissue damage via IFNγ.

Mineral trioxide aggregate: part 2 - a review of the material aspects.

PubMed

Malhotra, Neeraj; Agarwal, Antara; Mala, Kundabala

2013-03-01

The purpose of this two-part series is to review the composition, properties, and products of mineral trioxide aggregate (MTA) materials. PubMed and MedLine electronic databases were used to identify scientific papers from January 1991 to May 2010. Based on the selected inclusion criteria, citations were referenced from the scientific peer-reviewed dental literature. Mineral trioxide aggregate is a refined form of the parent compound, Portland cement (PC), and demonstrates a strong biocompatibility due to the high pH level and the material's ability to form hydroxyapatite. Mineral trioxide aggregate materials provide better microleakage protection than traditional endodontic materials as observed in findings from dye-leakage, fluid-filtration, protein-leakage, and bacterial penetration-leakage studies and has been recognized as a bioactive material. Various MTA commercial products are available, including gray mineral trioxide aggregate (GMTA), white mineral trioxide aggregate (WMTA), and mineral trioxide aggregate-Angelus (AMTA). Although these materials are indicated for various dental uses and applications, long-term in-vivo clinical studies are needed. Part 1 of this article highlighted and discussed the composition and characteristics of the material. Part 2 provides an overview of commercially available MTA materials.

An overview of aggregate resources in the United States

USGS Publications Warehouse

Langer, William H.; Scott, P.W.; Bristow, C.M.

2002-01-01

In 2000 the USA produced about 2.7 billion tonnes of aggregate worth about $13.7 billion. Both crushed stone and sand and gravel are produced in virtually every State, although limited quantities are available in the Gulf Coastal Plain, the Colorado Plateau , the Wyoming Basin and the Great Plains. Prices vary depending on the product and location. Most aggregates are transported by road, and minor amounts by railroad, barge on navigable inland channels, and through the Great Lake ports. Imports and exports of aggregates are very minor. A major amount f crushed stone aggregates is consumed by concrete aggregate. Recycled aggregates account for about 8% of total demand, although the amount recycled is thought to be increasing. Current issues facing the inductry unclude the differences in quality specifications between States, adjusting to the increasing concern for the impact of aggregate mining on the environmentm, health issues from particulate matter and crystalline silica, and the complexity of obtaining permits for extraction. Redcustion in the number od companies extracting aggregrates is likely to occur through acquisitions.

Effect of lightweight aggregates prepared from fly ash on lightweight concrete performances

NASA Astrophysics Data System (ADS)

Punlert, S.; Laoratanakul, P.; Kongdee, R.; Suntako, R.

2017-09-01

Lightweight aggregates were prepared from fly ash of by-products from the paper industry. The influence of the ratio of clay to fly ash and processing conditions on lightweight aggregates properties were investigated. It was found that the amount of fly ash directly affected to porosity of lightweight aggregates. Lightweight aggregates with the ratio of clay to fly ash at 80:20 wt% using the sintering temperature at 1210°C exhibits bulk density of 1.66 g cm-3, compressive strength of 25 MPa and water absorption of 0.55%. The replacement of coarse aggregates with lightweight aggregates at 100 wt% for concrete production showed the ultimate properties of concrete with density of 1780 g cm-3, water absorption of 3.55%, compressive strength of 40.94 MPa and thermal conductivity of 0.77 W m-1K-1. The concrete had more than 25% weight reduction while keeping a similar compressive strength to an ordinary concrete. This is revealed that lightweight aggregates could be applied into structural concrete because it was able to reduce work load and increase safety factor of construction.

Evaluating fishery rehabilitation under uncertainty: A bioeconomic analysis of quota management for the Green Bay yellow perch fishery

USGS Publications Warehouse

Johnson, B.L.; Milliman, S.R.; Bishop, R.C.; Kitchell, J.F.

1992-01-01

The fishery for yellow perch Perca flavescens in Green Bay, Lake Michigan, is currently operating under a rehabilitation plan based on a commercial harvest quota. We developed a bioeconomic computer model that included links between population density and growth, recruitment, and fishing effort for this fishery. Random variability was included in the stock-recruitment relation and in a simulated population assessment. We used the model in an adaptive management framework to evaluate the effects of the rehabilitation plan on both commercial and sport fisheries and to search for ways to improve the plan. Results indicate that the current quota policy is a member of a set of policies that would meet most management goals and increase total value of the fishery. Sensitivity analyses indicate that this conclusion is robust over a wide range of biological conditions. We predict that commercial fishers will lose money relative to the baseline condition, but they may receive other benefits from the elimination of the common-property nature of the fishery. The prospect exists for managing variability in harvest and stock size and for maximizing economic returns in the fishery, but more information is required, primarily on sportfishing effort dynamics and angler preferences. Stock-recruitment relations, density dependence of growth, and dynamics of sportfishing effort are the primary sources of uncertainty limiting the precision of our predictions. The current quota policy is about as good as other policies at reducing this uncertainty and appears, overall, to be one of the best choices for this fishery. The analytical techniques used in this study were primarily simple, heuristic approaches that could be easily transferred to other studies.

Aggregation of the rhizospheric bacterium Azospirillum brasilense in response to oxygen

NASA Astrophysics Data System (ADS)

Abdoun, Hamid; McMillan, Mary; Pereg, Lily

2016-04-01

Azospirillum brasilense spp. have ecological, scientific and agricultural importance. As model plant growth promoting rhizobacteria they interact with a large variety of plants, including important food and cash crops. Azospirillum strains are known for their production of plant growth hormones that enhance root systems and for their ability to fix nitrogen. Azospirillum cells transform in response to environmental cues. The production of exopolysaccharides and cell aggregation during cellular transformation are important steps in the attachment of Azospirillum to roots. We investigate signals that induce cellular transformation and aggregation in the Azospirillum and report on the importance of oxygen to the process of aggregation in this rhizospheric bacterium.

Building aggregate timber supply models from individual harvest choice

Treesearch

Maksym Polyakov; David N. Wear; Robert Huggett

2009-01-01

Timber supply has traditionally been modelled using aggregate data. In this paper, we build aggregate supply models for four roundwood products for the US state of North Carolina from a stand-level harvest choice model applied to detailed forest inventory. The simulated elasticities of pulpwood supply are much lower than reported by previous studies. Cross price...

Co-production of GroELS discriminates between intrinsic and thermally-induced recombinant protein aggregation during substrate quality control

PubMed Central

2011-01-01

Background The effects and effectiveness of the chaperone pair GroELS on the yield and quality of recombinant polypeptides produced in Escherichia coli are matter of controversy, as the reported activities of this complex are not always consistent and eventually indicate undesired side effects. The divergence in the reported data could be due, at least partially, to different experimental conditions in independent research approaches. Results We have then selected two structurally different model proteins (namely GFP and E. coli β-galactosidase) and two derived aggregation-prone fusions to explore, in a systematic way, the eventual effects of GroELS co-production on yield, solubility and conformational quality. Host cells were cultured at two alternative temperatures below the threshold at which thermal stress is expected to be triggered, to minimize the involvement of independent stress factors. Conclusions From the analysis of protein yield, solubility and biological activity of the four model proteins produced alone or along the chaperones, we conclude that GroELS impacts on yield and quality of aggregation-prone proteins with intrinsic determinants but not on thermally induced protein aggregation. No effective modifications of protein solubility have been observed, but significant stabilization of small (encapsulable) substrates and moderate chaperone-induced degradation of larger (excluded) polypeptides. These findings indicate that the activities of this chaperone pair in the context of actively producing recombinant bacteria discriminate between intrinsic and thermally-induced protein aggregation, and that the side effects of GroELS overproduction might be determined by substrate size. PMID:21992454

Particle Aggregation During Fe(III) Bioreduction in Nontronite

NASA Astrophysics Data System (ADS)

Jaisi, D. P.; Dong, H.; Hi, Z.; Kim, J.

2005-12-01

the particles size of 0.12-0.22 and 1.42-1.8 mm, respectively. The particle aggregation was limited in control experiment to the factor of 2.8 and 2.1 for these two size fractions, respectively. The measured electrophoretic mobility decreased with increase in the extent of bioreduction and aggregation, but the rate of decrease was greatest in the finest size fraction. The EPS measurements showed the increase in the carbohydrate and protein fractions as a result of bioreduction. Separate experiments were performed to understand the relative contribution of Fe(III) reduction and EPS production in controlling nontronite particle aggregation The rate of particle aggregation was measured for nontronite that was chemically pre-reduced by dithionite to various extents, both with and without addition of dextran, a neutral and pure EPS. The aggregation rate was greater in the nontronite that were pre-reduced to a higher extent than those with a lower extent of reduction. The relative contribution to particle aggregation due to Fe(III) reduction and polysaccharide bridging was about 4:1. However, in the real system where bacterial cells are involved, and amount of EPS production and extent of Fe(III) bioreduction increase with time, the relative contribution may be different than in this simple system. In summary, we conclude that both Fe(III) reduction and microbial production of EPS contribute to the observed nontronite particle aggregation with Fe(III) reduction playing more dominant role.

Calcium oxalate monohydrate aggregation induced by aggregation of desialylated Tamm-Horsfall protein

PubMed Central

Viswanathan, Pragasam; Rimer, Jeffrey D.; Kolbach, Ann M.; Kleinman, Jack G.

2011-01-01

Tamm-Horsfall protein (THP) is thought to protect against calcium oxalate monohydrate (COM) stone formation by inhibiting COM aggregation. Several studies reported that stone formers produce THP with reduced levels of glycosylation, particularly sialic acid levels, which leads to reduced negative charge. In this study, normal THP was treated with neuraminidase to remove sialic acid residues, confirmed by an isoelectric point shift to higher pH. COM aggregation assays revealed that desialylated THP (ds-THP) promoted COM aggregation, while normal THP inhibited aggregation. The appearance of protein aggregates in solutions at ds-THP concentrations ≥1 µg/mL in 150 mM NaCl correlated with COM aggregation promotion, implying that ds-THP aggregation induced COM aggregation. The aggregation-promoting effect of the ds-THP was independent of pH above its isoelectric point, but was substantially reduced at low ionic strength, where protein aggregation was much reduced. COM aggregation promotion was maximized at a ds-THP to COM mass ratio of ~0.025, which can be explained by a model wherein partial COM surface coverage by ds-THP aggregates promotes crystal aggregation by bridging opposing COM surfaces, whereas higher surface coverage leads to repulsion between adsorbed ds-THP aggregates. Thus, desialylation of THP apparently abrogates a normal defensive action of THP by inducing protein aggregation, and subsequently COM aggregation, a condition that favors kidney stone formation. PMID:21229239

New methods allowing the detection of protein aggregates

PubMed Central

Demeule, Barthélemy; Palais, Caroline; Machaidze, Gia; Gurny, Robert

2009-01-01

Aggregation compromises the safety and efficacy of therapeutic proteins. According to the manufacturer, the therapeutic immunoglobulin trastuzumab (Herceptin®) should be diluted in 0.9% sodium chloride before administration. Dilution in 5% dextrose solutions is prohibited. The reason for the interdiction is not mentioned in the Food and Drug Administration (FDA) documentation, but the European Medicines Agency (EMEA) Summary of Product Characteristics states that dilution of trastuzumab in dextrose solutions results in protein aggregation. In this paper, asymmetrical flow field-flow fractionation (FFF), fluorescence spectroscopy, fluorescence microscopy and transmission electron microscopy (TEM) have been used to characterize trastuzumab samples diluted in 0.9% sodium chloride, a stable infusion solution, as well as in 5% dextrose (a solution prone to aggregation). When trastuzumab samples were injected in the FFF channel using a standard separation method, no difference could be seen between trastuzumab diluted in sodium chloride and trastuzumab diluted in dextrose. However, during FFF measurements made with appropriate protocols, aggregates were detected in 5% dextrose. The parameters enabling the detection of reversible trastuzumab aggregates are described. Aggregates could also be documented by fluorescence microscopy and TEM. Fluorescence spectroscopy data were indicative of conformational changes consistent with increased aggregation and adsorption to surfaces. The analytical methods presented in this study were able to detect and characterize trastuzumab aggregates. PMID:20061815

Composition, buoyancy regulation and fate of ice algal aggregates in the Central Arctic Ocean.

PubMed

Fernández-Méndez, Mar; Wenzhöfer, Frank; Peeken, Ilka; Sørensen, Heidi L; Glud, Ronnie N; Boetius, Antje

2014-01-01

Sea-ice diatoms are known to accumulate in large aggregates in and under sea ice and in melt ponds. There is recent evidence from the Arctic that such aggregates can contribute substantially to particle export when sinking from the ice. The role and regulation of microbial aggregation in the highly seasonal, nutrient- and light-limited Arctic sea-ice ecosystem is not well understood. To elucidate the mechanisms controlling the formation and export of algal aggregates from sea ice, we investigated samples taken in late summer 2011 and 2012, during two cruises to the Eurasian Basin of the Central Arctic Ocean. Spherical aggregates densely packed with pennate diatoms, as well as filamentous aggregates formed by Melosira arctica showed sign of different stages of degradation and physiological stoichiometries, with carbon to chlorophyll a ratios ranging from 110 to 66700, and carbon to nitrogen molar ratios of 8-35 and 9-40, respectively. Sub-ice algal aggregate densities ranged between 1 and 17 aggregates m(-2), maintaining an estimated net primary production of 0.4-40 mg C m(-2) d(-1), and accounted for 3-80% of total phototrophic biomass and up to 94% of local net primary production. A potential factor controlling the buoyancy of the aggregates was light intensity, regulating photosynthetic oxygen production and the amount of gas bubbles trapped within the mucous matrix, even at low ambient nutrient concentrations. Our data-set was used to evaluate the distribution and importance of Arctic algal aggregates as carbon source for pelagic and benthic communities.

Composition, Buoyancy Regulation and Fate of Ice Algal Aggregates in the Central Arctic Ocean

PubMed Central

Fernández-Méndez, Mar; Wenzhöfer, Frank; Peeken, Ilka; Sørensen, Heidi L.; Glud, Ronnie N.; Boetius, Antje

2014-01-01

Sea-ice diatoms are known to accumulate in large aggregates in and under sea ice and in melt ponds. There is recent evidence from the Arctic that such aggregates can contribute substantially to particle export when sinking from the ice. The role and regulation of microbial aggregation in the highly seasonal, nutrient- and light-limited Arctic sea-ice ecosystem is not well understood. To elucidate the mechanisms controlling the formation and export of algal aggregates from sea ice, we investigated samples taken in late summer 2011 and 2012, during two cruises to the Eurasian Basin of the Central Arctic Ocean. Spherical aggregates densely packed with pennate diatoms, as well as filamentous aggregates formed by Melosira arctica showed sign of different stages of degradation and physiological stoichiometries, with carbon to chlorophyll a ratios ranging from 110 to 66700, and carbon to nitrogen molar ratios of 8–35 and 9–40, respectively. Sub-ice algal aggregate densities ranged between 1 and 17 aggregates m−2, maintaining an estimated net primary production of 0.4–40 mg C m−2 d−1, and accounted for 3–80% of total phototrophic biomass and up to 94% of local net primary production. A potential factor controlling the buoyancy of the aggregates was light intensity, regulating photosynthetic oxygen production and the amount of gas bubbles trapped within the mucous matrix, even at low ambient nutrient concentrations. Our data-set was used to evaluate the distribution and importance of Arctic algal aggregates as carbon source for pelagic and benthic communities. PMID:25208058

Feasibility Study on Manufacturing Lightweight Aggregates from Water Purification Sludge

NASA Astrophysics Data System (ADS)

Peng, Ching-Fang; Chen, How-Ji

2018-02-01

This study mainly discussed the feasibility of manufacturing lightweight aggregates from water purification sludge in Taiwan. They were analysed for the physical and chemical composition before the sintering test for lightweight aggregates in a laboratory. Then the physical and mechanical properties of the synthesized aggregates were assessed. The result showed that the chemical composition of sludge in the water purification plants was within the appropriate range for manufacturing lightweight aggregate as proposed in the literature. The sintering test demonstrated that the particle density of aggregates from the ten types of water purification sludge were mostly less than 1.8 g/cm3. In addition, the dry unit weight, the organic impurity, the ignition loss, and other characteristics of synthesized aggregates met the requirement of CNS standards, while its water absorption and crushing strength also fulfilled the general commercial specifications. Therefore, reclamation of water purification sludge for production of lightweight aggregate is indeed feasible.

Rydberg aggregates

NASA Astrophysics Data System (ADS)

Wüster, S.; Rost, J.-M.

2018-02-01

We review Rydberg aggregates, assemblies of a few Rydberg atoms exhibiting energy transport through collective eigenstates, considering isolated atoms or assemblies embedded within clouds of cold ground-state atoms. We classify Rydberg aggregates, and provide an overview of their possible applications as quantum simulators for phenomena from chemical or biological physics. Our main focus is on flexible Rydberg aggregates, in which atomic motion is an essential feature. In these, simultaneous control over Rydberg-Rydberg interactions, external trapping and electronic energies, allows Born-Oppenheimer surfaces for the motion of the entire aggregate to be tailored as desired. This is illustrated with theory proposals towards the demonstration of joint motion and excitation transport, conical intersections and non-adiabatic effects. Additional flexibility for quantum simulations is enabled by the use of dressed dipole-dipole interactions or the embedding of the aggregate in a cold gas or Bose-Einstein condensate environment. Finally we provide some guidance regarding the parameter regimes that are most suitable for the realization of either static or flexible Rydberg aggregates based on Li or Rb atoms. The current status of experimental progress towards enabling Rydberg aggregates is also reviewed.

Production of lightweight aggregates from mining residues, heavy metal sludge, and incinerator fly ash.

PubMed

Huang, Su-Chen; Chang, Fang-Chih; Lo, Shang-Lien; Lee, Ming-Yu; Wang, Chu-Fang; Lin, Jyh-Dong

2007-06-01

In this study, artificial lightweight aggregate (LWA) manufactured from recycled resources was investigated. Residues from mining, fly ash from an incinerator and heavy metal sludge from an electronic waste water plant were mixed into raw aggregate pellets and fed into a tunnel kiln to be sintered and finally cooled rapidly. Various feeding and sintering temperatures were employed to examine their impact on the extent of vitrification on the aggregate surface. Microstructural analysis and toxicity characteristic leaching procedure (TCLP) were also performed. The results show that the optimum condition of LWA fabrication is sintering at 1150 degrees C for 15 min with raw aggregate pellets fed at 750 degrees C. The rapidly vitrified surface envelops the gas produced with the increase in internal temperature and cooling by spraying water prevents the aggregates from binding together, thus forming LWA with specific gravity of 0.6. LWA produced by sintering in tunnel kiln shows good vitrified surface, low water absorption rate below 5%, and low cylindrical compressive strength of 4.3 MPa. In addition, only trace amounts of heavy metals were detected, making the LWA non-hazardous for construction use.

Sustainable management and supply of natural and recycled aggregates in a medium-size integrated plant.

PubMed

Faleschini, Flora; Zanini, Mariano Angelo; Pellegrino, Carlo; Pasinato, Stefano

2016-03-01

The consumption of natural aggregates in civil engineering applications can cause severe environmental impacts on a regional scale, depleting the stock of bulk resources within a territory. Several methods can improve the environmental sustainability of the whole aggregates' supply process, including natural and recycled aggregates' productive chains, for instance promoting the use of recycled aggregates (RA). However, when quarrying and recycling activities are considered as stand-alone processes, also the RA supply chain may not be as sustainable as expected, due to the high environmental loads associated to transportation, if high distances from the production to the use sites are involved. This work gives some insights on the environmental impact assessment of the aggregates' industry in the Italian context, through a comparative assessment of the environmental loads of natural and recycled aggregates' productive chains. An integrated plant for the extraction of virgin aggregates and recycling of construction and demolition waste (C&DW) was analyzed as significant case study, with the aim to identify the influence of sustainable solutions on the overall emissions of the facility. A Life Cycle Assessment (LCA) approach was used, using site-specific data and paying particular attention on transportation-related impacts, land use, avoided landfill and non-renewable resources preservation. From this work it was possible to evaluate the influence of transportation and PV energy use on the overall environmental emissions of natural and recycled aggregates' productive chains. Copyright © 2016 Elsevier Ltd. All rights reserved.

Microbial community dynamics in soil aggregates shape biogeochemical gas fluxes from soil profiles - upscaling an aggregate biophysical model.

PubMed

Ebrahimi, Ali; Or, Dani

2016-09-01

Microbial communities inhabiting soil aggregates dynamically adjust their activity and composition in response to variations in hydration and other external conditions. These rapid dynamics shape signatures of biogeochemical activity and gas fluxes emitted from soil profiles. Recent mechanistic models of microbial processes in unsaturated aggregate-like pore networks revealed a highly dynamic interplay between oxic and anoxic microsites jointly shaped by hydration conditions and by aerobic and anaerobic microbial community abundance and self-organization. The spatial extent of anoxic niches (hotspots) flicker in time (hot moments) and support substantial anaerobic microbial activity even in aerated soil profiles. We employed an individual-based model for microbial community life in soil aggregate assemblies represented by 3D angular pore networks. Model aggregates of different sizes were subjected to variable water, carbon and oxygen contents that varied with soil depth as boundary conditions. The study integrates microbial activity within aggregates of different sizes and soil depth to obtain estimates of biogeochemical fluxes from the soil profile. The results quantify impacts of dynamic shifts in microbial community composition on CO2 and N2 O production rates in soil profiles in good agreement with experimental data. Aggregate size distribution and the shape of resource profiles in a soil determine how hydration dynamics shape denitrification and carbon utilization rates. Results from the mechanistic model for microbial activity in aggregates of different sizes were used to derive parameters for analytical representation of soil biogeochemical processes across large scales of practical interest for hydrological and climate models. © 2016 John Wiley & Sons Ltd.

50 CFR Table 7 to Part 679 - Communities Determined To Be Eligible To Apply for Community Development Quotas

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Communities Determined To Be Eligible To Apply for Community Development Quotas 7 Table 7 to Part 679 Wildlife and Fisheries FISHERY CONSERVATION...) FISHERIES OF THE EXCLUSIVE ECONOMIC ZONE OFF ALASKA Pt. 679, Table 7 Table 7 to Part 679—Communities...

50 CFR Table 7 to Part 679 - Communities Determined To Be Eligible To Apply for Community Development Quotas

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Communities Determined To Be Eligible To Apply for Community Development Quotas 7 Table 7 to Part 679 Wildlife and Fisheries FISHERY CONSERVATION...) FISHERIES OF THE EXCLUSIVE ECONOMIC ZONE OFF ALASKA Pt. 679, Table 7 Table 7 to Part 679—Communities...

Floating ice-algal aggregates below melting arctic sea ice.

PubMed

Assmy, Philipp; Ehn, Jens K; Fernández-Méndez, Mar; Hop, Haakon; Katlein, Christian; Sundfjord, Arild; Bluhm, Katrin; Daase, Malin; Engel, Anja; Fransson, Agneta; Granskog, Mats A; Hudson, Stephen R; Kristiansen, Svein; Nicolaus, Marcel; Peeken, Ilka; Renner, Angelika H H; Spreen, Gunnar; Tatarek, Agnieszka; Wiktor, Jozef

2013-01-01

During two consecutive cruises to the Eastern Central Arctic in late summer 2012, we observed floating algal aggregates in the melt-water layer below and between melting ice floes of first-year pack ice. The macroscopic (1-15 cm in diameter) aggregates had a mucous consistency and were dominated by typical ice-associated pennate diatoms embedded within the mucous matrix. Aggregates maintained buoyancy and accumulated just above a strong pycnocline that separated meltwater and seawater layers. We were able, for the first time, to obtain quantitative abundance and biomass estimates of these aggregates. Although their biomass and production on a square metre basis was small compared to ice-algal blooms, the floating ice-algal aggregates supported high levels of biological activity on the scale of the individual aggregate. In addition they constituted a food source for the ice-associated fauna as revealed by pigments indicative of zooplankton grazing, high abundance of naked ciliates, and ice amphipods associated with them. During the Arctic melt season, these floating aggregates likely play an important ecological role in an otherwise impoverished near-surface sea ice environment. Our findings provide important observations and measurements of a unique aggregate-based habitat during the 2012 record sea ice minimum year.

Floating Ice-Algal Aggregates below Melting Arctic Sea Ice

PubMed Central

Assmy, Philipp; Ehn, Jens K.; Fernández-Méndez, Mar; Hop, Haakon; Katlein, Christian; Sundfjord, Arild; Bluhm, Katrin; Daase, Malin; Engel, Anja; Fransson, Agneta; Granskog, Mats A.; Hudson, Stephen R.; Kristiansen, Svein; Nicolaus, Marcel; Peeken, Ilka; Renner, Angelika H. H.; Spreen, Gunnar; Tatarek, Agnieszka; Wiktor, Jozef

2013-01-01

During two consecutive cruises to the Eastern Central Arctic in late summer 2012, we observed floating algal aggregates in the melt-water layer below and between melting ice floes of first-year pack ice. The macroscopic (1-15 cm in diameter) aggregates had a mucous consistency and were dominated by typical ice-associated pennate diatoms embedded within the mucous matrix. Aggregates maintained buoyancy and accumulated just above a strong pycnocline that separated meltwater and seawater layers. We were able, for the first time, to obtain quantitative abundance and biomass estimates of these aggregates. Although their biomass and production on a square metre basis was small compared to ice-algal blooms, the floating ice-algal aggregates supported high levels of biological activity on the scale of the individual aggregate. In addition they constituted a food source for the ice-associated fauna as revealed by pigments indicative of zooplankton grazing, high abundance of naked ciliates, and ice amphipods associated with them. During the Arctic melt season, these floating aggregates likely play an important ecological role in an otherwise impoverished near-surface sea ice environment. Our findings provide important observations and measurements of a unique aggregate-based habitat during the 2012 record sea ice minimum year. PMID:24204642

Automation of aggregate characterization using laser profiling and digital image analysis

NASA Astrophysics Data System (ADS)

Kim, Hyoungkwan

2002-08-01

Particle morphological properties such as size, shape, angularity, and texture are key properties that are frequently used to characterize aggregates. The characteristics of aggregates are crucial to the strength, durability, and serviceability of the structure in which they are used. Thus, it is important to select aggregates that have proper characteristics for each specific application. Use of improper aggregate can cause rapid deterioration or even failure of the structure. The current standard aggregate test methods are generally labor-intensive, time-consuming, and subject to human errors. Moreover, important properties of aggregates may not be captured by the standard methods due to a lack of an objective way of quantifying critical aggregate properties. Increased quality expectations of products along with recent technological advances in information technology are motivating new developments to provide fast and accurate aggregate characterization. The resulting information can enable a real time quality control of aggregate production as well as lead to better design and construction methods of portland cement concrete and hot mix asphalt. This dissertation presents a system to measure various morphological characteristics of construction aggregates effectively. Automatic measurement of various particle properties is of great interest because it has the potential to solve such problems in manual measurements as subjectivity, labor intensity, and slow speed. The main efforts of this research are placed on three-dimensional (3D) laser profiling, particle segmentation algorithms, particle measurement algorithms, and generalized particle descriptors. First, true 3D data of aggregate particles obtained by laser profiling are transformed into digital images. Second, a segmentation algorithm and a particle measurement algorithm are developed to separate particles and process each particle data individually with the aid of various kinds of digital image

78 FR 56657 - Notice of Solicitation of Applications for Allocation of Tariff Rate Quotas on the Import of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-13

... for Allocation of Tariff Rate Quotas on the Import of Certain Worsted Wool Fabrics to Persons Who Cut... fabric to persons who cut and sew men's and boys' worsted wool suits, suit-type jackets and trousers in..., corporations, or other legal entities) who cut and sew men's and boys' worsted wool suits, suit-type jackets...

77 FR 58524 - Notice of Solicitation of Applications for Allocation of Tariff Rate Quotas on the Import of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-21

... for Allocation of Tariff Rate Quotas on the Import of Certain Worsted Wool Fabrics to Persons Who Cut... fabric to persons who cut and sew men's and boys' worsted wool suits, suit-type jackets and trousers in..., corporations, or other legal entities) who cut and sew men's and boys' worsted wool suits, suit-type jackets...

Monitoring Insulin Aggregation via Capillary Electrophoresis

PubMed Central

Pryor, Elizabeth; Kotarek, Joseph A.; Moss, Melissa A.; Hestekin, Christa N.

2011-01-01

Early stages of insulin aggregation, which involve the transient formation of oligomeric aggregates, are an important aspect in the progression of Type II diabetes and in the quality control of pharmaceutical insulin production. This study is the first to utilize capillary electrophoresis (CE) with ultraviolet (UV) detection to monitor insulin oligomer formation at pH 8.0 and physiological ionic strength. The lag time to formation of the first detected species in the aggregation process was evaluated by UV-CE and thioflavin T (ThT) binding for salt concentrations from 100 mM to 250 mM. UV-CE had a significantly shorter (5–8 h) lag time than ThT binding (15–19 h). In addition, the lag time to detection of the first aggregated species via UV-CE was unaffected by salt concentration, while a trend toward an increased lag time with increased salt concentration was observed with ThT binding. This result indicates that solution ionic strength impacts early stages of aggregation and β-sheet aggregate formation differently. To observe whether CE may be applied for the analysis of biological samples containing low insulin concentrations, the limit of detection using UV and laser induced fluorescence (LIF) detection modes was determined. The limit of detection using LIF-CE, 48.4 pM, was lower than the physiological insulin concentration, verifying the utility of this technique for monitoring biological samples. LIF-CE was subsequently used to analyze the time course for fluorescein isothiocyanate (FITC)-labeled insulin oligomer formation. This study is the first to report that the FITC label prevented incorporation of insulin into oligomers, cautioning against the use of this fluorescent label as a tag for following early stages of insulin aggregation. PMID:22272138

Silicone Oil- and Agitation-Induced Aggregation of a Monoclonal Antibody in Aqueous Solution

PubMed Central

Thirumangalathu, Renuka; Krishnan, Sampathkumar; Ricci, Margaret Speed; Brems, David N.; Randolph, Theodore W.; Carpenter, John F.

2009-01-01

Silicone oil, which is used as a lubricant or coating in devices such as syringes, needles and pharmaceutical containers, has been implicated in aggregation and particulation of proteins and antibodies. Aggregation of therapeutic protein products induced by silicone oil can pose a challenge to their development and commercialization. To systematically characterize the role of silicone oil on protein aggregation, the effects of agitation, temperature, pH and ionic strength on silicone oil-induced loss of monomeric anti-streptavidin IgG 1 antibody were examined. Additionally, the influences of excipients polysorbate20 and sucrose on protein aggregation were investigated. In the absence of agitation, protein absorbed to silicone oil with approximately monolayer coverage, however silicone oil did not stimulate aggregation during isothermal incubation unless samples were also agitated. A synergistic stimulation of aggregation by a combination of agitation and silicone oil was observed. Solution conditions which reduced colloidal stability of the antibody, as assessed by determination of osmotic second virial coefficients, accelerated aggregation during agitation with silicone oil. Polysorbate20 completely inhibited silicone oil-induced monomer loss during agitation. A formulation strategy optimizing colloidal stability of the antibody as well as incorporation of surfactants such as polysorbate20 is proposed to reduce silicone oil-induced aggregation of therapeutic protein products. PMID:19360857

Sustainability in Supply Chain Management: Aggregate Planning from Sustainability Perspective.

PubMed

Türkay, Metin; Saraçoğlu, Öztürk; Arslan, Mehmet Can

2016-01-01

Supply chain management that considers the flow of raw materials, products and information has become a focal issue in modern manufacturing and service systems. Supply chain management requires effective use of assets and information that has far reaching implications beyond satisfaction of customer demand, flow of goods, services or capital. Aggregate planning, a fundamental decision model in supply chain management, refers to the determination of production, inventory, capacity and labor usage levels in the medium term. Traditionally standard mathematical programming formulation is used to devise the aggregate plan so as to minimize the total cost of operations. However, this formulation is purely an economic model that does not include sustainability considerations. In this study, we revise the standard aggregate planning formulation to account for additional environmental and social criteria to incorporate triple bottom line consideration of sustainability. We show how these additional criteria can be appended to traditional cost accounting in order to address sustainability in aggregate planning. We analyze the revised models and interpret the results on a case study from real life that would be insightful for decision makers.

Sustainability in Supply Chain Management: Aggregate Planning from Sustainability Perspective

PubMed Central

Türkay, Metin; Saraçoğlu, Öztürk; Arslan, Mehmet Can

2016-01-01

Supply chain management that considers the flow of raw materials, products and information has become a focal issue in modern manufacturing and service systems. Supply chain management requires effective use of assets and information that has far reaching implications beyond satisfaction of customer demand, flow of goods, services or capital. Aggregate planning, a fundamental decision model in supply chain management, refers to the determination of production, inventory, capacity and labor usage levels in the medium term. Traditionally standard mathematical programming formulation is used to devise the aggregate plan so as to minimize the total cost of operations. However, this formulation is purely an economic model that does not include sustainability considerations. In this study, we revise the standard aggregate planning formulation to account for additional environmental and social criteria to incorporate triple bottom line consideration of sustainability. We show how these additional criteria can be appended to traditional cost accounting in order to address sustainability in aggregate planning. We analyze the revised models and interpret the results on a case study from real life that would be insightful for decision makers. PMID:26807848

Effect of additives on mineral trioxide aggregate setting reaction product formation.

PubMed

Zapf, Angela M; Chedella, Sharath C V; Berzins, David W

2015-01-01

Mineral trioxide aggregate (MTA) sets via hydration of calcium silicates to yield calcium silicate hydrates and calcium hydroxide (Ca[OH]2). However, a drawback of MTA is its long setting time. Therefore, many additives have been suggested to reduce the setting time. The effect those additives have on setting reaction product formation has been ignored. The objective was to examine the effect additives have on MTA's setting time and setting reaction using differential scanning calorimetry (DSC). MTA powder was prepared with distilled water (control), phosphate buffered saline, 5% calcium chloride (CaCl2), 3% sodium hypochlorite (NaOCl), or lidocaine in a 3:1 mixture and placed in crucibles for DSC evaluation. The setting exothermic reactions were evaluated at 37°C for 8 hours to determine the setting time. Separate samples were stored and evaluated using dynamic DSC scans (37°C→640°C at10°C/min) at 1 day, 1 week, 1 month, and 3 months (n = 9/group/time). Dynamic DSC quantifies the reaction product formed from the amount of heat required to decompose it. Thermographic peaks were integrated to determine enthalpy, which was analyzed with analysis of variance/Tukey test (α = 0.05). Isothermal DSC identified 2 main exothermal peaks occurring at 44 ± 12 and 343 ± 57 minutes for the control. Only the CaCl2 additive was an accelerant, which was observed by a greater exothermic peak at 101 ± 11 minutes, indicating a decreased setting time. The dynamic DSC scans produced an endothermic peak around 450°C-550°C attributed to Ca(OH)2 decomposition. The use of a few additives (NaOCl and lidocaine) resulted in significantly less Ca(OH)2 product formation. DSC was used to discriminate calcium hydroxide formation in MTA mixed with various additives and showed NaOCl and lidocaine are detrimental to MTA reaction product formation, whereas CaCl2 accelerated the reaction. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

Combining control measures for more effective management of fisheries under uncertainty: quotas, effort limitation and protected areas.

PubMed

Stefansson, Gunnar; Rosenberg, Andrew A

2005-01-29

We consider combinations of three types of control measures for the management of fisheries when the input information for policy decisions is uncertain. The methods considered include effort controls, catch quotas and area closures. We simulated a hypothetical fishery loosely based on the Icelandic cod fishery, using a simple spatially explicit dynamic model. We compared the performance with respect to conserving the resource and economic return for each type of control measure alone and in combination. In general, combining more than one type of primary direct control on fishing provides a greater buffer to uncertainty than any single form of fishery control alone. Combining catch quota control with a large closed area is a most effective system for reducing the risk of stock collapse and maintaining both short and long-term economic performance. Effort controls can also be improved by adding closed areas to the management scheme. We recommend that multiple control methods be used wherever possible and that closed areas should be used to buffer uncertainty. To be effective, these closed areas must be large and exclude all principal gears to provide real protection from fishing mortality.

Combining control measures for more effective management of fisheries under uncertainty: quotas, effort limitation and protected areas

PubMed Central

Stefansson, Gunnar; Rosenberg, Andrew A.

2005-01-01

We consider combinations of three types of control measures for the management of fisheries when the input information for policy decisions is uncertain. The methods considered include effort controls, catch quotas and area closures. We simulated a hypothetical fishery loosely based on the Icelandic cod fishery, using a simple spatially explicit dynamic model. We compared the performance with respect to conserving the resource and economic return for each type of control measure alone and in combination. In general, combining more than one type of primary direct control on fishing provides a greater buffer to uncertainty than any single form of fishery control alone. Combining catch quota control with a large closed area is a most effective system for reducing the risk of stock collapse and maintaining both short and long-term economic performance. Effort controls can also be improved by adding closed areas to the management scheme. We recommend that multiple control methods be used wherever possible and that closed areas should be used to buffer uncertainty. To be effective, these closed areas must be large and exclude all principal gears to provide real protection from fishing mortality. PMID:15713593

Lipopolysaccharide treatment reduces rat platelet aggregation independent of intracellular reactive-oxygen species generation.

PubMed

Lopes-Pires, M Elisa; Casarin, André L; Pereira-Cunha, Fernanda G; Lorand-Metze, Irene; Antunes, Edson; Marcondes, Sisi

2012-01-01

High production of reactive-oxygen species (ROS) by blood cells is involved in damage of the vascular endothelium and multiple organ dysfunction in sepsis. However, little is known about the intraplatelet ROS production in sepsis and its consequences on platelet reactivity. In this study, we evaluated whether the treatment of rats with lipopolysaccharide (LPS) affects platelet aggregation through intraplatelet ROS generation. Rats were injected with LPS (1 mg/kg, i.p.), and at 2 to 72 h thereafter, adenosine diphosphate (ADP) (3-10 µM) induced platelet aggregation was evaluated. Production of ROS in platelets was measured by flow cytometry using 2',7'-dichlorofluorescein diacetate (DCFH-DA). Treatment of rats with LPS time-dependently inhibited ADP-induced platelet aggregation within 72 h. The inhibitory effect of LPS on platelet aggregation was further increased when the platelets were incubated with polyethylene glycol-superoxide dismutase (PEG-SOD; 30 U/mL), polyethylene glycol-catalase (PEG-CAT; 1000 U/mL) or the NADPH oxidase inhibitor diphenyleneiodonium (DPI; 10 µM). The ROS production in non-stimulated platelets did not differ between control and LPS-treated rats. However, in ADP-activated platelets, generation of ROS was increased by 3.0- and 7.0-fold, as evaluated at 8 and 48 h after LPS injection, respectively. This increased ROS production was significantly reduced when platelets were incubated in vitro with DPI, PEG-SOD or PEG-CAT. In contrast, treatment of rats with N-acetylcysteine (150 mg/kg, i.p.) significantly reduced the inhibitory effect of LPS on platelet aggregation, and prevented the increased ROS production by in vivo LPS. Our results indicate that the increased intraplatelet ROS production does not contribute to the inhibitory effect of LPS on platelet aggregation; however, the maintenance of redox balance in LPS-treated rats is fundamental to restore the normal platelet response in these animals.

The aggregation paths and products of Aβ42 dimers are distinct from Aβ42 monomer

PubMed Central

O'Malley, Tiernan T.; Witbold, William M.; Linse, Sara; Walsh, Dominic M.

2017-01-01

Extracts of Alzheimer's disease (AD) brain that contain what appear to be SDS-stable amyloid β-protein (Aβ) dimers potently block LTP and impair memory consolidation. Brain-derived dimers can be physically separated from Aβ monomer, consist primarily of Aβ42 and resist denaturation by powerful chaotropic agents. In nature, covalently cross-linked Aβ dimers could be generated in only one of two different ways - either by the formation of a dityrosine (DiY) or an isopeptide ε-(γ-glutamyl)-lysine (Q-K) bond. We enzymatically cross-linked recombinant Aβ42 monomer to produce DiY and Q-K dimers and then applied a range of biophysical methods to study their aggregation. Both Q-K and DiY dimers aggregate to form soluble assemblies distinct from the fibrillar aggregates formed by Aβ monomer. These results suggest that Aβ dimers allow the formation of soluble aggregates akin to those in aqueous extracts of AD brain. Thus it seems that Aβ dimers may play an important role in determining the formation of soluble rather than insoluble aggregates. PMID:27750419

Thermal Aggregation of Calcium-Fortified Skim Milk Enhances Probiotic Protection during Convective Droplet Drying.

PubMed

Wang, Juan; Huang, Song; Fu, Nan; Jeantet, Romain; Chen, Xiao Dong

2016-08-03

Probiotic bacteria have been reported to confer benefits on hosts when delivered in an adequate dose. Spray-drying is expected to produce dried and microencapsulated probiotic products due to its low production cost and high energy efficiency. The bottleneck in probiotic application addresses the thermal and dehydration-related inactivation of bacteria during process. A protective drying matrix was designed by modifying skim milk with the principle of calcium-induced protein thermal aggregation. The well-defined single-droplet drying technique was used to monitor the droplet-particle conversion and the protective effect of this modified Ca-aggregated milk on Lactobacillus rhamnosus GG. The Ca-aggregated milk exhibited a higher drying efficiency and superior protection on L. rhamnosus GG during thermal convective drying. The mechanism was explained by the aggregation in milk, causing the lower binding of water in the serum phase and, conversely, local concentrated milk aggregates involved in bacteria entrapment in the course of drying. This work may open new avenues for the development of probiotic products with high bacterial viability and calcium enrichment.

75 FR 54598 - Notice of Solicitation of Applications for Allocation of Tariff Rate Quotas on the Import of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-08

... for Allocation of Tariff Rate Quotas on the Import of Certain Worsted Wool Fabrics to Persons Who Cut... fabric to persons who cut and sew men's and boys' worsted wool suits, suit-type jackets and trousers in..., corporations, or other legal entities) who cut and sew men's and boys' worsted wool suits and suit-like jackets...

76 FR 58465 - Notice of Solicitation of Applications for Allocation of Tariff Rate Quotas on the Import of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-21

... for Allocation of Tariff Rate Quotas on the Import of Certain Worsted Wool Fabrics to Persons Who Cut... persons who cut and sew men's and boys' worsted wool suits, suit-type jackets and trousers in the United..., or other legal entities) who cut and sew men's and boys' worsted wool suits and suit-like jackets and...

Eco-friendly porous concrete using bottom ash aggregate for marine ranch application.

PubMed

Lee, Byung Jae; Prabhu, G Ganesh; Lee, Bong Chun; Kim, Yun Yong

2016-03-01

This article presents the test results of an investigation carried out on the reuse of coal bottom ash aggregate as a substitute material for coarse aggregate in porous concrete production for marine ranch applications. The experimental parameters were the rate of bottom ash aggregate substitution (30%, 50% and 100%) and the target void ratio (15%, 20% and 25%). The cement-coated granular fertiliser was substituted into a bottom ash aggregate concrete mixture to improve marine ranch applications. The results of leaching tests revealed that the bottom ash aggregate has only a negligible amount of the ten deleterious substances specified in the Ministry of Environment - Enforcement Regulation of the Waste Management Act of Republic Korea. The large amount of bubbles/air gaps in the bottom ash aggregate increased the voids of the concrete mixtures in all target void ratios, and decreased the compressive strength of the porous concrete mixture; however, the mixture substituted with 30% and 10% of bottom ash aggregate and granular fertiliser, respectively, showed an equal strength to the control mixture. The sea water resistibility of the bottom ash aggregate substituted mixture was relatively equal to that of the control mixture, and also showed a great deal of improvement in the degree of marine organism adhesion compared with the control mixture. No fatality of fish was observed in the fish toxicity test, which suggested that bottom ash aggregate was a harmless material and that the combination of bottom ash aggregate and granular fertiliser with substitution rates of 30% and 10%, respectively, can be effectively used in porous concrete production for marine ranch application. © The Author(s) 2015.

Aggregation of the Inflammatory S100A8 Precedes Aβ Plaque Formation in Transgenic APP Mice: Positive Feedback for S100A8 and Aβ Productions.

PubMed

Lodeiro, Maria; Puerta, Elena; Ismail, Muhammad-Al-Mustafa; Rodriguez-Rodriguez, Patricia; Rönnbäck, Annica; Codita, Alina; Parrado-Fernandez, Cristina; Maioli, Silvia; Gil-Bea, Francisco; Merino-Serrais, Paula; Cedazo-Minguez, Angel

2017-03-01

Inflammation plays an important role in Alzheimer's disease (AD) and other neurodegenerative disorders. Although chronic inflammation in later stages of AD is well described, little is known about the inflammatory processes in preclinical or early stages of the disease prior to plaque deposition. In this study, we report that the inflammatory mediator S100A8 is increased with aging in the mouse brain. It is observed as extracellular aggregates, which do not correspond to corpora amylacea. S100A8 aggregation is enhanced in the hippocampi of two different mouse models for amyloid-β (Aβ) overproduction (Tg2576 and TgAPParctic mice). S100A8 aggregates are seen prior the formation of Aβ plaques and do not colocalize. In vitro treatment of glial cells from primary cultures with Aβ42 resulted in an increased production of S100A8. In parallel, treatment of a neuronal cell line with recombinant S100A8 protein resulted in enhanced Aβ42 and decreased Aβ40 production. Our results suggest that important inflammatory processes are occurring prior to Aβ deposition and the existence of a positive feedback between S100A8 and Aβ productions. The possible relevance of aging- or AD-dependent formation of S100A8 aggregates in the hippocampus thus affecting learning and memory processes is discussed. © The Author 2016. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Coherent and incoherent ultrasound backscatter from cell aggregates.

PubMed

de Monchy, Romain; Destrempes, François; Saha, Ratan K; Cloutier, Guy; Franceschini, Emilie

2016-09-01

The effective medium theory (EMT) was recently developed to model the ultrasound backscatter from aggregating red blood cells [Franceschini, Metzger, and Cloutier, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 58, 2668-2679 (2011)]. The EMT assumes that aggregates can be treated as homogeneous effective scatterers, which have effective properties determined by the aggregate compactness and the acoustical characteristics of the cells and the surrounding medium. In this study, the EMT is further developed to decompose the differential backscattering cross section of a single cell aggregate into coherent and incoherent components. The coherent component corresponds to the squared norm of the average scattering amplitude from the effective scatterer, and the incoherent component considers the variance of the scattering amplitude (i.e., the mean squared norm of the fluctuation of the scattering amplitude around its mean) within the effective scatterer. A theoretical expression for the incoherent component based on the structure factor is proposed and compared with another formulation based on the Gaussian direct correlation function. This theoretical improvement is assessed using computer simulations of ultrasound backscatter from aggregating cells. The consideration of the incoherent component based on the structure factor allows us to approximate the simulations satisfactorily for a product of the wavenumber times the aggregate radius kr ag around 2.

Mechanical and Physical Properties of Hydrophobized Lightweight Aggregate Concrete with Sewage Sludge

PubMed Central

Suchorab, Zbigniew; Barnat-Hunek, Danuta; Franus, Małgorzata; Łagód, Grzegorz

2016-01-01

This article is focused on lightweight aggregate-concrete modified by municipal sewage sludge and lightweight aggregate-concrete obtained from light aggregates. The article presents laboratory examinations of material physical parameters. Water absorptivity of the examined material was decreased by the admixture of water emulsion of reactive polysiloxanes. Water transport properties were determined using Time Domain Reflectometry, an indirect technique for moisture detection in porous media. Together with basic physical parameters, the heat conductivity coefficient λ was determined for both types of lightweight aggregate-concrete. Analysis of moisture and heat properties of the examined materials confirmed the usefulness of light aggregates supplemented with sewage sludge for prospective production. PMID:28773442

Mechanical and Physical Properties of Hydrophobized Lightweight Aggregate Concrete with Sewage Sludge.

PubMed

Suchorab, Zbigniew; Barnat-Hunek, Danuta; Franus, Małgorzata; Łagód, Grzegorz

2016-04-27

This article is focused on lightweight aggregate-concrete modified by municipal sewage sludge and lightweight aggregate-concrete obtained from light aggregates. The article presents laboratory examinations of material physical parameters. Water absorptivity of the examined material was decreased by the admixture of water emulsion of reactive polysiloxanes. Water transport properties were determined using Time Domain Reflectometry, an indirect technique for moisture detection in porous media. Together with basic physical parameters, the heat conductivity coefficient λ was determined for both types of lightweight aggregate-concrete. Analysis of moisture and heat properties of the examined materials confirmed the usefulness of light aggregates supplemented with sewage sludge for prospective production.

"Forty Acres and a Mule," With Interest: The Constitutionality of Black Capitalism, Benign School Quotas, and Other Statutory Racial Classifications

ERIC Educational Resources Information Center

Elden, Gary

1969-01-01

This article traces the growth and assesses contemporary patterns and consequences of, discrimination against the American Negro. The author contends that public policies designed to support black capitalism" and implement school racial quotas, are not only legal but necessary means toward achieving true equality of opportunity. (JH)

Geologic and societal factors affecting the international oceanic transport of aggregate

USGS Publications Warehouse

Langer, W.H.

1995-01-01

Crushed stone and sand and gravel are the two main sources of natural aggregate, and together comprise approximately half the volume and tonnage of mined material in the United States. Natural aggregate is a bulky, heavy material without special or unique properties, and it is commonly used near its source of production to minimize haulage cost. However, remoteness is no longer an absolute disqualifier for the production of aggregate. Today interstate aggregate routinely is shipped hundreds of kilometers by rail and barge. In addition, during 1992, the United States imported 1,317,000 metric tons of aggregate from Canada and 1,531,000 metric tons from Mexico. A number of ports on the Atlantic Coast and Gulf Coast of the United States receive imports of crushed stone from foreign sources for transport to various parts of the eastern United States. These areas either lack adequate supplies of aggregate or are augmenting their supplies because they have difficulties meeting current demand. These difficulties may include poor stone quality, environmental permitting problems, or transportation. Certain societal and geologic conditions of New York City and Philadelphia along the Atlantic Coast, and Tampa and New Orleans along the Gulf Coast, are discussed to demonstrate the different combinations of issues that contribute to the economic viability of importing crushed stone. ?? 1995 Oxford University Press.

The Effects of Different Fine Recycled Concrete Aggregates on the Properties of Mortar

PubMed Central

Fan, Cheng-Chih; Huang, Ran; Hwang, Howard; Chao, Sao-Jeng

2015-01-01

The practical use of recycled concrete aggregate produced by crushing concrete waste reduces the consumption of natural aggregate and the amount of concrete waste that ends up in landfills. This study investigated two methods used in the production of fine recycled concrete aggregate: (1) a method that produces fine as well as coarse aggregate, and (2) a method that produces only fine aggregate. Mortar specimens were tested using a variety of mix proportions to determine how the characteristics of fine recycled concrete aggregate affect the physical and mechanical properties of the resulting mortars. Our results demonstrate the superiority of mortar produced using aggregate produced using the second of the two methods. Nonetheless, far more energy is required to render concrete into fine aggregate than is required to produce coarse as well as fine aggregate simultaneously. Thus, the performance benefits of using only fine recycled concrete aggregate must be balanced against the increased impact on the environment.

Use of Air-cooled Blast Furnace Slag as Coarse Aggregate in Concrete Pavements

DOT National Transportation Integrated Search

2012-03-01

This report presents available information regarding the use of air-cooled blast furnace slag (ACBFS) as coarse aggregate in concrete pavements. The report discusses ACBFS aggregate production and properties, and the properties of concrete produced w...

Reduction in soil aggregation in response to dust emission processes

NASA Astrophysics Data System (ADS)

Swet, Nitzan; Katra, Itzhak

2016-09-01

Dust emission by aeolian (wind) soil erosion depends on the topsoil properties of the source area, especially on the nature of the aggregates where most dust particles are held. Although the key role of soil aggregates in dust emission, the response of soil aggregation to aeolian processes and its implications for dust emission remain unknown. This study focuses on aggregate size distribution (ASD) analyses before and after in-situ aeolian experiments in semiarid loess soils that are associated with dust emission. Wind tunnel simulations show that particulate matter (PM) emission and saltation rates depend on the initial ASD and shear velocity. Under all initial ASD conditions, the content of saltator-sized aggregates (63-250 μm) increased by 10-34% due to erosion of macro-aggregates (> 500 μm), resulting in a higher size ratio (SR) between the saltators and macro-aggregates following the aeolian erosion. The results revealed that the saltator production increases significantly for soils that are subjected to short-term (anthropogenic) disturbance of the topsoil. The findings highlight a decrease in soil aggregation for all initial ASD's in response to aeolian erosion, and consequently its influence on the dust emission potential. Changes in ASD should be considered as a key parameter in dust emission models of complex surfaces.

Effect of protein-surfactant interactions on aggregation of β-lactoglobulin.

PubMed

Hansted, Jon G; Wejse, Peter L; Bertelsen, Hans; Otzen, Daniel E

2011-05-01

The milk protein β-lactoglobulin (βLG) dominates the properties of whey aggregates in food products. Here we use spectroscopic and calorimetric techniques to elucidate how anionic, cationic and non-ionic surfactants interact with bovine βLG and modulate its heat-induced aggregation. Alkyl trimethyl ammonium chlorides (xTAC) strongly promote aggregation, while sodium alkyl sulfates (SxS) and alkyl maltopyranosides (xM) reduce aggregation. Sodium dodecyl sulfate (SDS) binds to non-aggregated βLG in several steps, but reduction of aggregation was associated with the first binding step, which occurs far below the critical micelle concentration. In contrast, micellar concentrations of xMs are required to reduce aggregation. The ranking order for reduction of aggregation (normalized to their tendency to self-associate) was C10-C12>C8>C14 for SxS and C8>C10>C12>C14>C16 for xM. xTAC promote aggregation in the same ranking order as xM reduce it. We conclude that SxS reduce aggregation by stabilizing the protein's ligand-bound state (the melting temperature t(m) increases by up to 10°C) and altering its charge potential. xM monomers also stabilize the protein's ligand-bound state (increasing t(m) up to 6°C) but in the absence of charged head groups this is not sufficient by itself to prevent aggregation. Although micelles of both anionic and non-ionic surfactants destabilize βLG, they also solubilize unfolded protein monomers, leaving them unavailable for protein-protein association and thus inhibiting aggregation. Cationic surfactants promote aggregation by a combination of destabilization and charge neutralization. The food compatible surfactant sodium dodecanoate also inhibited aggregation well below the cmc, suggesting that surfactants may be a practical way to modulate whey protein properties. Copyright © 2011 Elsevier B.V. All rights reserved.

Coal Combustion Wastes Reuse in Low Energy Artificial Aggregates Manufacturing.

PubMed

Ferone, Claudio; Colangelo, Francesco; Messina, Francesco; Iucolano, Fabio; Liguori, Barbara; Cioffi, Raffaele

2013-10-31

Sustainable building material design relies mostly on energy saving processes, decrease of raw materials consumption, and increase of waste and by-products recycling. Natural and lightweight artificial aggregates production implies relevant environmental impact. This paper addresses both the issues of residues recycling and energy optimization. Particularly, three coal combustion wastes (Weathered Fly Ash, WFA; Wastewater Treatment Sludge, WTS; Desulfurization Device Sludge, DDS) supplied by the Italian electric utility company (ENEL) have been employed in the manufacture of cold bonded artificial aggregates. Previously, the residues have been characterized in terms of chemical and mineralogical compositions, water content, particle size distribution, and heavy metal release behavior. These wastes have been used in the mix design of binding systems with the only addition of lime. Finally, the artificial aggregates have been submitted to physical, mechanical, and leaching testing, revealing that they are potentially suitable for many civil engineering applications.

Coal Combustion Wastes Reuse in Low Energy Artificial Aggregates Manufacturing

PubMed Central

Ferone, Claudio; Colangelo, Francesco; Messina, Francesco; Iucolano, Fabio; Liguori, Barbara; Cioffi, Raffaele

2013-01-01

Sustainable building material design relies mostly on energy saving processes, decrease of raw materials consumption, and increase of waste and by-products recycling. Natural and lightweight artificial aggregates production implies relevant environmental impact. This paper addresses both the issues of residues recycling and energy optimization. Particularly, three coal combustion wastes (Weathered Fly Ash, WFA; Wastewater Treatment Sludge, WTS; Desulfurization Device Sludge, DDS) supplied by the Italian electric utility company (ENEL) have been employed in the manufacture of cold bonded artificial aggregates. Previously, the residues have been characterized in terms of chemical and mineralogical compositions, water content, particle size distribution, and heavy metal release behavior. These wastes have been used in the mix design of binding systems with the only addition of lime. Finally, the artificial aggregates have been submitted to physical, mechanical, and leaching testing, revealing that they are potentially suitable for many civil engineering applications. PMID:28788372

Production of heterotrophic bacteria inhabiting macroscopic organic aggregates (marine snow) from surface waters

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alldredge, A.L.; Cole, J.J.; Caron, D.A.

1986-01-01

Macroscopic detrital aggregates, known as marine snow, are a ubiquitous and abundant component of the marine pelagic zone. Descriptions of microbial communities occurring at densities 2-5 orders of magnitude higher on these particles than in the surrounding seawater have led to the suggestion that marine snow may be a site of intense heterotrophic activity. The authors tested this hypothesis using incorporation of (/sup 3/H)thymidine into macromolecules as a measure of bacterial growth occurring on marine snow from oceanic waters in the North Atlantic and from neritic waters off southern California. Abundances of marine snow ranged from 0.1 to 4.3 aggregatesmore » per liter. However, only 0.1-4% ration per cell on aggregates was generally equal to or lower than that of bacteria found free-living in the surrounding seawater, indicating that attached bacteria were not growing more rapidly than free-living bacteria. Bacteria inhabiting aggregates were up to 25 times larger than free-living forms.« less

Guidance to Achieve Accurate Aggregate Quantitation in Biopharmaceuticals by SV-AUC.

PubMed

Arthur, Kelly K; Kendrick, Brent S; Gabrielson, John P

2015-01-01

The levels and types of aggregates present in protein biopharmaceuticals must be assessed during all stages of product development, manufacturing, and storage of the finished product. Routine monitoring of aggregate levels in biopharmaceuticals is typically achieved by size exclusion chromatography (SEC) due to its high precision, speed, robustness, and simplicity to operate. However, SEC is error prone and requires careful method development to ensure accuracy of reported aggregate levels. Sedimentation velocity analytical ultracentrifugation (SV-AUC) is an orthogonal technique that can be used to measure protein aggregation without many of the potential inaccuracies of SEC. In this chapter, we discuss applications of SV-AUC during biopharmaceutical development and how characteristics of the technique make it better suited for some applications than others. We then discuss the elements of a comprehensive analytical control strategy for SV-AUC. Successful implementation of these analytical control elements ensures that SV-AUC provides continued value over the long time frames necessary to bring biopharmaceuticals to market. © 2015 Elsevier Inc. All rights reserved.

Activated stress response pathways within multicellular aggregates utilize an autocrine component.

PubMed

Jack, Graham D; Cabrera, M Carla; Manning, Michael L; Slaughter, Stephen M; Potts, Malcolm; Helm, Richard F

2007-04-01

Multicellular aggregates (spheroids) of primary human foreskin fibroblasts (HFF-2) and a glioblastoma cell line (T98G) entered and exited from long term (2 weeks) metabolic arrest utilizing an autocrine response. Cytokine production (specifically IFN-gamma) activated a Gadd45alpha/p38 pathway that led to increased AP-1 (c-jun and ATF3) transcription factor levels, augmenting cytokine production in an autocrine fashion. Whereas HFF-2 aggregates were capable of surviving long term arrest and recovery during NF-kappaB inhibition independent of JNK activation, T98G aggregates were not. Such endogenous processes are not easily observed with adherent monolayer cell culturing systems, strongly suggesting that more emphasis needs to be placed on determining the operational signal transduction cascades within multicellular aggregates. Extracellular inputs such as spheroid formation, arrest, and regrowth as monolayers invoke intracellular signaling responses converging at the AP-1 transcription factor level. Variations in responses are both cell type and transformation state dependent and require an autocrine cytokine component. The data are discussed in relation to the wounding response and avascular tumor growth mechanisms.

Feeding on dispersed vs. aggregated particles: The effect of zooplankton feeding behavior on vertical flux.

PubMed

Koski, Marja; Boutorh, Julia; de la Rocha, Christina

2017-01-01

Zooplankton feeding activity is hypothesized to attenuate the downward flux of elements in the ocean. We investigated whether the zooplankton community composition could influence the flux attenuation, due to the differences of feeding modes (feeding on dispersed vs. aggregated particles) and of metabolic rates. We fed 5 copepod species-three calanoid, one harpacticoid and one poecilamastoid-microplankton food, in either dispersed or aggregated form and measured rates of respiration, fecal pellet production and egg production. Calanoid copepods were able to feed only on dispersed food; when their food was introduced as aggregates, their pellet production and respiration rates decreased to rates observed for starved individuals. In contrast, harpacticoids and the poecilamastoid copepod Oncaea spp. were able to feed only when the food was in the form of aggregates. The sum of copepod respiration, pellet production and egg production rates was equivalent to a daily minimum carbon demand of ca. 10% body weight-1 for all non-feeding copepods; the carbon demand of calanoids feeding on dispersed food was 2-3 times greater, and the carbon demand of harpacticoids and Oncaea spp. feeding on aggregates was >7 times greater, than the resting rates. The zooplankton species composition combined with the type of available food strongly influences the calculated carbon demand of a copepod community, and thus also the attenuation of vertical carbon flux.

Feeding on dispersed vs. aggregated particles: The effect of zooplankton feeding behavior on vertical flux

PubMed Central

Boutorh, Julia; de la Rocha, Christina

2017-01-01

Zooplankton feeding activity is hypothesized to attenuate the downward flux of elements in the ocean. We investigated whether the zooplankton community composition could influence the flux attenuation, due to the differences of feeding modes (feeding on dispersed vs. aggregated particles) and of metabolic rates. We fed 5 copepod species—three calanoid, one harpacticoid and one poecilamastoid–microplankton food, in either dispersed or aggregated form and measured rates of respiration, fecal pellet production and egg production. Calanoid copepods were able to feed only on dispersed food; when their food was introduced as aggregates, their pellet production and respiration rates decreased to rates observed for starved individuals. In contrast, harpacticoids and the poecilamastoid copepod Oncaea spp. were able to feed only when the food was in the form of aggregates. The sum of copepod respiration, pellet production and egg production rates was equivalent to a daily minimum carbon demand of ca. 10% body weight-1 for all non-feeding copepods; the carbon demand of calanoids feeding on dispersed food was 2–3 times greater, and the carbon demand of harpacticoids and Oncaea spp. feeding on aggregates was >7 times greater, than the resting rates. The zooplankton species composition combined with the type of available food strongly influences the calculated carbon demand of a copepod community, and thus also the attenuation of vertical carbon flux. PMID:28545095

Protein aggregates as depots for the release of biologically active compounds.

PubMed

Artemova, Natalya V; Kasakov, Alexei S; Bumagina, Zoya M; Lyutova, Elena M; Gurvits, Bella Ya

2008-12-12

Protein misfolding and aggregation is one of the most serious problems in cell biology, molecular medicine, and biotechnology. Misfolded proteins interact with each other or with other proteins in non-productive or damaging ways. However, a new paradigm arises that protein aggregation may be exploited by nature to perform specific functions in different biological contexts. From this consideration, acceleration of stress-induced protein aggregation triggered by any factor resulting in the formation of soluble aggregates may have paradoxical positive consequences. Here, we suggest that amorphous aggregates can act as a source for the release of biologically active proteins after removal of stress conditions. To address this concept, we investigated the kinetics of thermal aggregation in vitro of yeast alcohol dehydrogenase (ADH) as a model substrate in the presence of two amphiphilic peptides: Arg-Phe or Ala-Phe-Lys. Using dynamic light scattering (DLS) and turbidimetry, we have demonstrated that under mild stress conditions the concentration-dependent acceleration of ADH aggregation by these peptides results in formation of large but soluble complexes of proteins prone to refolding.

GEOMETRIC CROSS SECTIONS OF DUST AGGREGATES AND A COMPRESSION MODEL FOR AGGREGATE COLLISIONS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Suyama, Toru; Wada, Koji; Tanaka, Hidekazu

2012-07-10

Geometric cross sections of dust aggregates determine their coupling with disk gas, which governs their motions in protoplanetary disks. Collisional outcomes also depend on geometric cross sections of initial aggregates. In a previous paper, we performed three-dimensional N-body simulations of sequential collisions of aggregates composed of a number of sub-micron-sized icy particles and examined radii of gyration (and bulk densities) of the obtained aggregates. We showed that collisional compression of aggregates is not efficient and that aggregates remain fluffy. In the present study, we examine geometric cross sections of the aggregates. Their cross sections decrease due to compression as wellmore » as to their gyration radii. It is found that a relation between the cross section and the gyration radius proposed by Okuzumi et al. is valid for the compressed aggregates. We also refine the compression model proposed in our previous paper. The refined model enables us to calculate the evolution of both gyration radii and cross sections of growing aggregates and reproduces well our numerical results of sequential aggregate collisions. The refined model can describe non-equal-mass collisions as well as equal-mass cases. Although we do not take into account oblique collisions in the present study, oblique collisions would further hinder compression of aggregates.« less

Defining and systematic analyses of aggregation indices to evaluate degree of calcium oxalate crystal aggregation

NASA Astrophysics Data System (ADS)

Chaiyarit, Sakdithep; Thongboonkerd, Visith

2017-12-01

Crystal aggregation is one of the most crucial steps in kidney stone pathogenesis. However, previous studies of crystal aggregation were rarely done and quantitative analysis of aggregation degree was handicapped by a lack of the standard measurement. We thus performed an in vitro assay to generate aggregation of calcium oxalate monohydrate (COM) crystals with various concentrations (25-800 µg/ml) in saturated aggregation buffer. The crystal aggregates were analyzed by microscopic examination, UV-visible spectrophotometry, and GraphPad Prism6 software to define a total of 12 aggregation indices (including number of aggregates, aggregated mass index, optical density, aggregation coefficient, span, number of aggregates at plateau time-point, aggregated area index, aggregated diameter index, aggregated symmetry index, time constant, half-life, and rate constant). The data showed linear correlation between crystal concentration and almost all of these indices, except only for rate constant. Among these, number of aggregates provided the greatest regression coefficient (r=0.997; p<0.001), whereas the equally second rank included aggregated mass index and optical density (r=0.993; p<0.001 and r=‑0.993; p<0.001, respectively) and the equally forth were aggregation coefficient and span (r=0.991; p<0.001 for both). These five indices are thus recommended as the most appropriate indices for quantitative analysis of COM crystal aggregation in vitro.

Cellulose Aggregation under Hydrothermal Pretreatment Conditions.

PubMed

Silveira, Rodrigo L; Stoyanov, Stanislav R; Kovalenko, Andriy; Skaf, Munir S

2016-08-08

Cellulose, the most abundant biopolymer on Earth, represents a resource for sustainable production of biofuels. Thermochemical treatments make lignocellulosic biomaterials more amenable to depolymerization by exposing cellulose microfibrils to enzymatic or chemical attacks. In such treatments, the solvent plays fundamental roles in biomass modification, but the molecular events underlying these changes are still poorly understood. Here, the 3D-RISM-KH molecular theory of solvation has been employed to analyze the role of water in cellulose aggregation under different thermodynamic conditions. The results show that, under ambient conditions, highly structured hydration shells around cellulose create repulsive forces that protect cellulose microfibrils from aggregating. Under hydrothermal pretreatment conditions, however, the hydration shells lose structure, and cellulose aggregation is favored. These effects are largely due to a decrease in cellulose-water interactions relative to those at ambient conditions, so that cellulose-cellulose attractive interactions become prevalent. Our results provide an explanation to the observed increase in the lateral size of cellulose crystallites when biomass is subject to pretreatments and deepen the current understanding of the mechanisms of biomass modification.

Utilizing dynamic light scattering as a process analytical technology for protein folding and aggregation monitoring in vaccine manufacturing.

PubMed

Yu, Zhou; Reid, Jennifer C; Yang, Yan-Ping

2013-12-01

Protein aggregation is a common challenge in the manufacturing of biological products. It is possible to minimize the extent of aggregation through timely measurement and in-depth characterization of aggregation. In this study, we demonstrated the use of dynamic light scattering (DLS) to monitor inclusion body (IB) solubilization, protein refolding, and aggregation near the production line of a recombinant protein-based vaccine candidate. Our results were in good agreement with those measured by size-exclusion chromatography. DLS was also used to characterize the mechanism of aggregation. As DLS is a quick, nonperturbing technology, it can potentially be used as an at-line process analytical technology to ensure complete IB solubilization and aggregate-free refolding. © 2013 Wiley Periodicals, Inc. and the American Pharmacists Association.

Integrating habits and practices data for soaps, cosmetics and air care products into an existing aggregate exposure model.

PubMed

Comiskey, D; Api, A M; Barrett, C; Ellis, G; McNamara, C; O'Mahony, C; Robison, S H; Rose, J; Safford, B; Smith, B; Tozer, S

2017-08-01

In order to accurately assess aggregate exposure to a fragrance material in consumers, data are needed on consumer habits and practices, as well as the concentration of the fragrance material in those products. The present study describes the development of Phase 2 Creme RIFM model by expanding the previously developed Phase 1 model to include an additional six product types. Using subject-matching algorithms, the subjects in the Phase 1 Creme RIFM database were paired with subjects in the SUPERB and BodyCare surveys based on age and gender. Consumption of the additional products was simulated to create a seven day diary allowing full data integration in a consistent format. The inhalation route was also included for air care and other products where a fraction of product used is inhaled, derived from the RIFM 2-box model. The expansion of the Phase 1 Creme RIFM model has resulted in a more extensive and refined model, which covers a broader range of product categories and now, includes all relevant routes of exposure. An evaluation of the performance of the model has been carried out in an accompanying publication to this one. Copyright © 2017 Elsevier Inc. All rights reserved.

Thermodynamics of Protein Aggregation

NASA Astrophysics Data System (ADS)

Osborne, Kenneth L.; Barz, Bogdan; Bachmann, Michael; Strodel, Birgit

Amyloid protein aggregation characterizes many neurodegenerative disorders, including Alzheimer's, Parkinson's, and Creutz- feldt-Jakob disease. Evidence suggests that amyloid aggregates may share similar aggregation pathways, implying simulation of full-length amyloid proteins is not necessary for understanding amyloid formation. In this study we simulate GNNQQNY, the N-terminal prion-determining domain of the yeast protein Sup35 to investigate the thermodynamics of structural transitions during aggregation. We use a coarse-grained model with replica-exchange molecular dynamics to investigate the association of 3-, 6-, and 12-chain GNNQQNY systems and we determine the aggregation pathway by studying aggregation states of GN- NQQNY. We find that the aggregation of the hydrophilic GNNQQNY sequence is mainly driven by H-bond formation, leading to the formation of /3-sheets from the very beginning of the assembly process. Condensation (aggregation) and ordering take place simultaneously, which is underpinned by the occurrence of a single heat capacity peak only.

A human-scale perspective on global warming: Zero emission year and personal quotas.

PubMed

de la Fuente, Alberto; Rojas, Maisa; Mac Lean, Claudia

2017-01-01

This article builds on the premise that human consumption of goods, food and transport are the ultimate drivers of climate change. However, the nature of the climate change problem (well described as a tragedy of the commons) makes it difficult for individuals to recognise their personal duty to implement behavioural changes to reduce greenhouse gas emissions. Consequently, this article aims to analyse the climate change issue from a human-scale perspective, in which each of us has a clearly defined personal quota of CO2 emissions that limits our activity and there is a finite time during which CO2 emissions must be eliminated to achieve the "well below 2°C" warming limit set by the Paris Agreement of 2015 (COP21). Thus, this work's primary contribution is to connect an equal per capita fairness approach to a global carbon budget, linking personal levels with planetary levels. Here, we show that a personal quota of 5.0 tons of CO2 yr-1 p-1 is a representative value for both past and future emissions; for this level of a constant per-capita emissions and without considering any mitigation, the global accumulated emissions compatible with the "well below 2°C" and 2°C targets will be exhausted by 2030 and 2050, respectively. These are references years that provide an order of magnitude of the time that is left to reverse the global warming trend. More realistic scenarios that consider a smooth transition toward a zero-emission world show that the global accumulated emissions compatible with the "well below 2°C" and 2°C targets will be exhausted by 2040 and 2080, respectively. Implications of this paper include a return to personal responsibility following equity principles among individuals, and a definition of boundaries to the personal emissions of CO2.

A human-scale perspective on global warming: Zero emission year and personal quotas

PubMed Central

Rojas, Maisa; Mac Lean, Claudia

2017-01-01

This article builds on the premise that human consumption of goods, food and transport are the ultimate drivers of climate change. However, the nature of the climate change problem (well described as a tragedy of the commons) makes it difficult for individuals to recognise their personal duty to implement behavioural changes to reduce greenhouse gas emissions. Consequently, this article aims to analyse the climate change issue from a human-scale perspective, in which each of us has a clearly defined personal quota of CO2 emissions that limits our activity and there is a finite time during which CO2 emissions must be eliminated to achieve the “well below 2°C” warming limit set by the Paris Agreement of 2015 (COP21). Thus, this work’s primary contribution is to connect an equal per capita fairness approach to a global carbon budget, linking personal levels with planetary levels. Here, we show that a personal quota of 5.0 tons of CO2 yr-1 p-1 is a representative value for both past and future emissions; for this level of a constant per-capita emissions and without considering any mitigation, the global accumulated emissions compatible with the “well below 2°C” and 2°C targets will be exhausted by 2030 and 2050, respectively. These are references years that provide an order of magnitude of the time that is left to reverse the global warming trend. More realistic scenarios that consider a smooth transition toward a zero-emission world show that the global accumulated emissions compatible with the “well below 2°C” and 2°C targets will be exhausted by 2040 and 2080, respectively. Implications of this paper include a return to personal responsibility following equity principles among individuals, and a definition of boundaries to the personal emissions of CO2. PMID:28628676

A study on the performance of concrete containing recycled aggregates and ceramic as materials replacement

NASA Astrophysics Data System (ADS)

Azmi, N. B.; Khalid, F. S.; Irwan, J. M.; Anting, N.; Mazenan, P. N.

2017-11-01

Natural fine aggregate materials are commonly used in development and commercial construction in Malaysia. In fact, concrete production was increased as linear with the growing Malaysia economy. However, an issue was production of concrete was to locate adequate sources of natural fine aggregates. There lot of studies have been conducted in order to replace the fine aggregate in which natural fine aggregate replace with the waste material in concrete preparation. Therefore, this study aims to utilize the Recycled Concrete Aggregate (RCA) and ceramic waste which has great potential to replace the natural aggregate in concrete mix with different type of method, admixture, and parameters. This research were focused on compressive strength and water absorption test to determine the optimum mix ratio of concrete mix. The concrete aggregate was chosen due to improvement capillary bonding mechanisms and ceramic presented similar strength compared to the conventional concrete using natural aggregate. Percent of replacement have been used in this study was at 25%, 35% and 45% of the RCA and 5%, 10% and 15% for ceramic, respectively. Furthermore, this research was conduct to find the optimum percentage of aggregate replacement, using water-cement ratio of 0.55 with concrete grade 25/30. The best percentage of replacement was the RCA35% C15% with the compressive strength of 34.72 MPa and the water absorption was satisfied.

Neuroforecasting Aggregate Choice

PubMed Central

Knutson, Brian; Genevsky, Alexander

2018-01-01

Advances in brain-imaging design and analysis have allowed investigators to use neural activity to predict individual choice, while emerging Internet markets have opened up new opportunities for forecasting aggregate choice. Here, we review emerging research that bridges these levels of analysis by attempting to use group neural activity to forecast aggregate choice. A survey of initial findings suggests that components of group neural activity might forecast aggregate choice, in some cases even beyond traditional behavioral measures. In addition to demonstrating the plausibility of neuroforecasting, these findings raise the possibility that not all neural processes that predict individual choice forecast aggregate choice to the same degree. We propose that although integrative choice components may confer more consistency within individuals, affective choice components may generalize more broadly across individuals to forecast aggregate choice. PMID:29706726

50 CFR Table 7 to Part 679 - Community Development Quota Groups and Communities Eligible To Participate in the CDQ Program

Code of Federal Regulations, 2012 CFR

2012-10-01

... 50 Wildlife and Fisheries 13 2012-10-01 2012-10-01 false Community Development Quota Groups and Communities Eligible To Participate in the CDQ Program 7 Table 7 to Part 679 Wildlife and Fisheries FISHERY...) FISHERIES OF THE EXCLUSIVE ECONOMIC ZONE OFF ALASKA Pt. 679, Table 7 Table 7 to Part 679—Community...

50 CFR Table 7 to Part 679 - Community Development Quota Groups and Communities Eligible To Participate in the CDQ Program

Code of Federal Regulations, 2013 CFR

2013-10-01

... 50 Wildlife and Fisheries 13 2013-10-01 2013-10-01 false Community Development Quota Groups and Communities Eligible To Participate in the CDQ Program 7 Table 7 to Part 679 Wildlife and Fisheries FISHERY...) FISHERIES OF THE EXCLUSIVE ECONOMIC ZONE OFF ALASKA Pt. 679, Table 7 Table 7 to Part 679—Community...

50 CFR Table 7 to Part 679 - Community Development Quota Groups and Communities Eligible To Participate in the CDQ Program

Code of Federal Regulations, 2014 CFR

2014-10-01

... 50 Wildlife and Fisheries 13 2014-10-01 2014-10-01 false Community Development Quota Groups and Communities Eligible To Participate in the CDQ Program 7 Table 7 to Part 679 Wildlife and Fisheries FISHERY...) FISHERIES OF THE EXCLUSIVE ECONOMIC ZONE OFF ALASKA Pt. 679, Table 7 Table 7 to Part 679—Community...

Aggregates from natural and recycled sources; economic assessments for construction applications; a materials flow study

USGS Publications Warehouse

Wilburn, David R.; Goonan, Thomas G.

1998-01-01

Increased amounts of recycled materials are being used to supplement natural aggregates (derived from crushed stone, sand and gravel) in road construction. An understanding of the economics and factors affecting the level of aggregates recycling is useful in estimating the potential for recycling and in assessing the total supply picture of aggregates. This investigation includes a descriptive analysis of the supply sources, technology, costs, incentives, deterrents, and market relationships associated with the production of aggregates.

Auto-aggregation properties of a novel aerobic denitrifier Enterobacter sp. strain FL.

PubMed

Wang, Xia; An, Qiang; Zhao, Bin; Guo, Jin Song; Huang, Yuan Sheng; Tian, Meng

2018-02-01

Enterobacter sp. strain FL was newly isolated from activated sludge and exhibited significant capability of auto-aggregation as well as aerobic denitrification. The removal efficiencies of NO 3 - -N, total nitrogen (TN), and TOC by strain FL in batch culture reached 94.6, 63.9, and 72.5% in 24 h, respectively. The production of N 2 O and N 2 in the presence of oxygen demonstrated the occurrence of aerobic denitrification. The auto-aggregation index of strain FL reached 54.3%, suggesting a high tendency that the cells would agglomerate into aggregates. The production of extracellular polymeric substances (EPSs), which were mainly composed of proteins followed by polysaccharides, was considered to be related to the cell aggregation according to Fourier transform infrared (FT-IR) and confocal laser scanning microscopy (CLSM). The proteins in EPS were evenly and tightly combined to cells and altered the protein secondary structures of cell surface from random coils to β-sheets and three-turn helices. The alteration of protein secondary structures of cell surface caused by the proteins in EPS might play a dominant role in the auto-aggregation of strain FL. To further assess the feasibility of strain FL for synthetic wastewater treatment, a sequencing batch reactor (SBR), solely inoculated with strain FL, was conducted. During the 16 running cycles, the removal efficiency of NO 3 - -N was 90.2-99.7% and the auto-aggregation index was stabilized at 35.0-41.5%. The EPS promoted the biomass of strain FL to aggregate in the SBR.

Recovery of MSWI and soil washing residues as concrete aggregates.

PubMed

Sorlini, Sabrina; Abbà, Alessandro; Collivignarelli, Carlo

2011-02-01

The aim of the present work was to study if municipal solid waste incinerator (MSWI) residues and aggregates derived from contaminated soil washing could be used as alternative aggregates for concrete production. Initially, chemical, physical and geometric characteristics (according to UNI EN 12620) of municipal solid waste incineration bottom ashes and some contaminated soils were evaluated; moreover, the pollutants release was evaluated by means of leaching tests. The results showed that the reuse of pre-treated MSWI bottom ash and washed soil is possible, either from technical or environmental point of view, while it is not possible for the raw wastes. Then, the natural aggregate was partially and totally replaced with these recycled aggregates for the production of concrete mixtures that were characterized by conventional mechanical and leaching tests. Good results were obtained using the same dosage of a high resistance cement (42.5R calcareous Portland cement instead of 32.5R); the concrete mixture containing 400 kg/m(3) of washed bottom ash and high resistance cement was classified as structural concrete (C25/30 class). Regarding the pollutants leaching, all concrete mixtures respected the limit values according to the Italian regulation. Copyright © 2010 Elsevier Ltd. All rights reserved.

Potential source for crushed granite aggregate in Heard County, Georgia

USGS Publications Warehouse

Atkins, R.L.; Higgins, Michael W.; Dickerson, Robert P.

1981-01-01

The production of crushed stone suitable for highway and general construction is a major industry in Georgia. The state ranks eighth in the nation in overall crushed stone production, and first in crushed granite production. Crushed stone production in Georgia in 1979 was 40,902,000 short tons worth $154,021,000 (D.H. White, Jr., US Bureau of Mines, personal commun., Aug. 1980). More than 3,000 people were employed by the crushed stone industry in Georgia during that year.Presently, the only active quarry in Heard County is located in an amphibolite. Amphibolite is not a conventional aggregate. It has a high specific gravity, a tendency to make elongate fragments, and varies considerably in abrasion tests.Because the nearest approved aggregate quarry is more than 25 miles from Franklin, the county seat, the purpose of this brief report is to describe a body of granite gneiss that may provide suitable aggregate for the crushed stone industry, potential quarry operators and various agencies in Heard County. This report is part of a project to study the geology and mineral resources of the Piedmont south of the Brevard Zone, and is not intended to supplant detailed site investigations by industry or consultants. The report is a joint effort between the Georgia Geologic Survey and the Office of Materials and Research of the Georgia Department of Transportation.

Patterns of [PSI+] aggregation allow insights into cellular organization of yeast prion aggregates

PubMed Central

Tyedmers, Jens

2012-01-01

The yeast prion phenomenon is very widespread and mounting evidence suggests that it has an impact on cellular regulatory mechanisms related to phenotypic responses to changing environments. Studying the aggregation patterns of prion amyloids during different stages of the prion life cycle is a first key step to understand major principles of how and where cells generate, organize and turn-over prion aggregates. The induction of the [PSI+] state involves the actin cytoskeleton and quality control compartments such as the Insoluble Protein Deposit (IPOD). An initially unstable transitional induction state can be visualized by overexpression of the prion determinant and displays characteristic large ring- and ribbon-shaped aggregates consisting of poorly fragmented bundles of very long prion fibrils. In the mature prion state, the aggregation pattern is characterized by highly fragmented, shorter prion fibrils that form aggregates, which can be visualized through tagging with fluorescent proteins. The number of aggregates formed varies, ranging from a single large aggregate at the IPOD to multiple smaller ones, depending on several parameters discussed. Aggregate units below the resolution of light microscopy that are detectable by fluorescence correlation spectroscopy are in equilibrium with larger aggregates in this stage and can mediate faithful inheritance of the prion state. Loss of the prion state is often characterized by reduced fragmentation of prion fibrils and fewer, larger aggregates. PMID:22449721

Aggregated Recombinant Human Interferon Beta Induces Antibodies but No Memory in Immune-Tolerant Transgenic Mice

PubMed Central

Sauerborn, Melody; Gilli, Francesca; Brinks, Vera; Schellekens, Huub; Jiskoot, Wim

2010-01-01

ABSTRACT Purpose To study the influence of protein aggregation on the immunogenicity of recombinant human interferon beta (rhIFNβ) in wild-type mice and transgenic, immune-tolerant mice, and to evaluate the induction of immunological memory. Methods RhIFNβ-1b and three rhIFNβ-1a preparations with different aggregate levels were injected intraperitoneally in mice 15× during 3 weeks, and the mice were rechallenged with rhIFNβ-1a. The formation of binding (BABs) and neutralizing antibodies (NABs) was monitored. Results Bulk rhIFNβ-1a contained large, mainly non-covalent aggregates and stressed rhIFNβ-1a mainly covalent, homogeneous (ca. 100 nm) aggregates. Reformulated rhIFNβ-1a was essentially aggregate-free. All products induced BABs and NABs in wild-type mice. Immunogenicity in the transgenic mice was product dependent. RhIFNβ-1b showed the highest and reformulated rhIFNβ-1a the lowest immunogenicity. In contrast with wild-type mice, transgenic mice did not show NABs, nor did they respond to the rechallenge. Conclusions The immunogenicity of the products in transgenic mice, unlike in wild-type mice, varied. In the transgenic mice, neither NABs nor immunological memory developed. The immunogenicity of rhIFNβ in a model reflecting the human immune system depends on the presence and the characteristics of aggregates. PMID:20499141

Quantification of alginate by aggregation induced by calcium ions and fluorescent polycations.

PubMed

Zheng, Hewen; Korendovych, Ivan V; Luk, Yan-Yeung

2016-01-01

For quantification of polysaccharides, including heparins and alginates, the commonly used carbazole assay involves hydrolysis of the polysaccharide to form a mixture of UV-active dye conjugate products. Here, we describe two efficient detection and quantification methods that make use of the negative charges of the alginate polymer and do not involve degradation of the targeted polysaccharide. The first method utilizes calcium ions to induce formation of hydrogel-like aggregates with alginate polymer; the aggregates can be quantified readily by staining with a crystal violet dye. This method does not require purification of alginate from the culture medium and can measure the large amount of alginate that is produced by a mucoid Pseudomonas aeruginosa culture. The second method employs polycations tethering a fluorescent dye to form suspension aggregates with the alginate polyanion. Encasing the fluorescent dye in the aggregates provides an increased scattering intensity with a sensitivity comparable to that of the conventional carbazole assay. Both approaches provide efficient methods for monitoring alginate production by mucoid P. aeruginosa. Copyright © 2015 Elsevier Inc. All rights reserved.

Intra-aggregate CO2 enrichment: a modelling approach for aerobic soils

NASA Astrophysics Data System (ADS)

Schlotter, D.; Schack-Kirchner, H.

2013-02-01

CO2 concentration gradients inside soil aggregates, caused by the respiration of soil microorganisms and fungal hyphae, might lead to variations in the soil solution chemistry on a mm-scale, and to an underestimation of the CO2 storage. But, up to now, there seems to be no feasible method for measuring CO2 inside natural aggregates with sufficient spatial resolution. We combined a one-dimensional model for gas diffusion in the inter-aggregate pore space with a cylinder diffusion model, simulating the consumption/production and diffusion of O2 and CO2 inside soil aggregates with air- and water-filled pores. Our model predicts that for aerobic respiration (respiratory quotient = 1) the intra-aggregate increase in the CO2 partial pressure can never be higher than 0.9 kPa for siliceous, and 0.1 kPa for calcaric aggregates, independent of the level of water-saturation. This suggests that only for siliceous aggregates CO2 produced by aerobic respiration might cause a high small-scale spatial variability in the soil solution chemistry. In calcaric aggregates, however, the contribution of carbonate species to the CO2 transport should lead to secondary carbonates on the aggregate surfaces. As regards the total CO2 storage in aerobic soils, both siliceous and calcaric, the effect of intra-aggregate CO2 gradients seems to be negligible. To assess the effect of anaerobic respiration on the intra-aggregate CO2 gradients, the development of a device for measuring CO2 on a mm-scale in soils is indispensable.

Equine cloning: in vitro and in vivo development of aggregated embryos.

PubMed

Gambini, Andrés; Jarazo, Javier; Olivera, Ramiro; Salamone, Daniel F

2012-07-01

The production of cloned equine embryos remains highly inefficient. Embryo aggregation has not yet been tested in the equine, and it might represent an interesting strategy to improve embryo development. This study evaluated the effect of cloned embryo aggregation on in vitro and in vivo equine embryo development. Zona-free reconstructed embryos were individually cultured in microwells (nonaggregated group) or as 2- or 3-embryo aggregates (aggregated groups). For in vitro development, they were cultured until blastocyst stage and then either fixed for Oct-4 immunocytochemical staining or maintained in in vitro culture where blastocyst expansion was measured daily until Day 17 or the day on which they collapsed. For in vivo assays, Day 7-8 blastocysts were transferred to synchronized mares and resultant vesicles, and cloned embryos were measured by ultrasonography. Embryo aggregation improved blastocyst rates on a per well basis, and aggregation did not imply additional oocytes to obtain blastocysts. Embryo aggregation improved embryo quality, nevertheless it did not affect Day 8 and Day 16 blastocyst Oct-4 expression patterns. Equine cloned blastocysts expanded and increased their cell numbers when they were maintained in in vitro culture, describing a particular pattern of embryo growth that was unexpectedly independent of embryo aggregation, as all embryos reached similar size after Day 7. Early pregnancy rates were higher using blastocysts derived from aggregated embryos, and advanced pregnancies as live healthy foals also resulted from aggregated embryos. These results indicate that the strategy of aggregating embryos can improve their development, supporting the establishment of equine cloned pregnancies.

Computational study of aggregation mechanism in human lysozyme[D67H

PubMed Central

Patel, Dharmeshkumar

2017-01-01

Aggregation of proteins is an undesired phenomena that affects both human health and bioengineered products such as therapeutic proteins. Finding preventative measures could be facilitated by a molecular-level understanding of dimer formation, which is the first step in aggregation. Here we present a molecular dynamics (MD) study of dimer formation propensity in human lysozyme and its D67H variant. Because the latter protein aggregates while the former does not, they offer an ideal system for testing the feasibility of the proposed MD approach which comprises three stages: i) partially unfolded conformers involved in dimer formation are generated via high-temperature MD simulations, ii) potential dimer structures are searched using docking and refined with MD, iii) free energy calculations are performed to find the most stable dimer structure. Our results provide a detailed explanation for how a single mutation (D67H) turns human lysozyme from non-aggregating to an aggregating protein. Conversely, the proposed method can be used to identify the residues causing aggregation in a protein, which can be mutated to prevent it. PMID:28467454

Effect of aggregate graining compositions on skid resistance of Exposed Aggregate Concrete pavement

NASA Astrophysics Data System (ADS)

Wasilewska, Marta; Gardziejczyk, Wladysław; Gierasimiuk, Pawel

2018-05-01

The paper presents the evaluation of skid resistance of EAC (Exposed Aggregate Concrete) pavements which differ in aggregate graining compositions. The tests were carried out on concrete mixes with a maximum aggregate size of 8 mm. Three types of coarse aggregates were selected depending on their resistance to polishing which was determined on the basis of the PSV (Polished Stone Value). Basalt (PSV 48), gabbro (PSV 50) and trachybasalt (PSV 52) aggregates were chosen. For each type of aggregate three graining compositions were designed, which differed in the content of coarse aggregate > 4mm. Their content for each series was as follows: A - 38%, B - 50% and C - 68%. Evaluation of the skid resistance has been performed using the FAP (Friction After Polishing) test equipment also known as the Wehner/Schulze machine. Laboratory method enables to compare the skid resistance of different types of wearing course under specified conditions simulating polishing processes. In addition, macrotexture measurements were made on the surface of each specimen using the Elatexure laser profile. Analysis of variance showed that at significance level α = 0.05, aggregate graining compositions as well as the PSV have a significant influence on the obtained values of the friction coefficient μm of the tested EAC pavements. The highest values of the μm have been obtained for EAC with the lowest amount of coarse aggregates (compositions A). In these cases the resistance to polishing of the aggregate does not significantly affect the friction coefficients. This is related to the large areas of cement mortar between the exposed coarse grains. Based on the analysis of microscope images, it was observed that the coarse aggregates were not sufficiently exposed. It has been proved that PSV significantly affected the coefficient of friction in the case of compositions B and C. This is caused by large areas of exposed coarse aggregate. The best parameters were achieved for the EAC pavements

Evaluation of Canadian unconfined aggregate freeze-thaw tests for identifying nondurable aggregates.

DOT National Transportation Integrated Search

2012-06-01

Concrete is the most widely used material in construction. Aggregates contribute 60% to 75% of the total volume : of concrete. The aggregates play a key role in concrete durability. The U.S. Midwest has many aggregates that can : show distress in the...

Heat-Induced Soluble Protein Aggregates from Mixed Pea Globulins and β-Lactoglobulin.

PubMed

Chihi, Mohamed-Lazhar; Mession, Jean-luc; Sok, Nicolas; Saurel, Rémi

2016-04-06

The present work investigates the formation of protein aggregates (85 °C, 60 min incubation) upon heat treatment of β-lactoglobulin (βlg)-pea globulins (Glob) mixtures at pH 7.2 and 5 mM NaCl from laboratory-prepared protein isolates. Various βlg/Glob weight ratios were applied, for a total protein concentration of 2 wt % in admixture. Different analytical methods were used to determine the aggregation behavior of "mixed" aggregates, that is, surface hydrophobicity and also sulfhydryl content, protein interactions by means of SDS-PAGE electrophoresis, and molecule size distribution by DLS and gel filtration. The production of "mixed" thermal aggregates would involve both the formation of new disulfide bonds and noncovalent interactions between the denatured βlg and Glob subunits. The majority of "mixed" soluble aggregates displayed higher molecular weight and smaller diameter than those for Glob heated in isolation. The development of pea-whey protein "mixed" aggregates may help to design new ingredients for the control of innovative food textures.

Traffic-induced changes and processes in forest road aggregate particle-size distributions

Treesearch

Hakjun Rhee; James Fridley; Deborah Page-Dumroese

2018-01-01

Traffic can alter forest road aggregate material in various ways, such as by crushing, mixing it with subgrade material, and sweeping large-size, loose particles (gravel) toward the outside of the road. Understanding the changes and physical processes of the aggregate is essential to mitigate sediment production from forest roads and reduce road maintenance efforts. We...

Flocculation kinetics and aggregate structure of kaolinite mixtures in laminar tube flow.

PubMed

Vaezi G, Farid; Sanders, R Sean; Masliyah, Jacob H

2011-03-01

Flocculation is commonly used in various solid-liquid separation processes in chemical and mineral industries to separate desired products or to treat waste streams. This paper presents an experimental technique to study flocculation processes in laminar tube flow. This approach allows for more realistic estimation of the shear rate to which an aggregate is exposed, as compared to more complicated shear fields (e.g. stirred tanks). A direct sampling method is used to minimize the effect of sampling on the aggregate structure. A combination of aggregate settling velocity and image analysis was used to quantify the structure of the aggregate. Aggregate size, density, and fractal dimension were found to be the most important aggregate structural parameters. The two methods used to determine aggregate fractal dimension were in good agreement. The effects of advective flow through an aggregate's porous structure and transition-regime drag coefficient on the evaluation of aggregate density were considered. The technique was applied to investigate the flocculation kinetics and the evolution of the aggregate structure of kaolin particles with an anionic flocculant under conditions similar to those of oil sands fine tailings. Aggregates were formed using a well controlled two-stage aggregation process. Detailed statistical analysis was performed to investigate the establishment of dynamic equilibrium condition in terms of aggregate size and density evolution. An equilibrium steady state condition was obtained within 90 s of the start of flocculation; after which no further change in aggregate structure was observed. Although longer flocculation times inside the shear field could conceivably cause aggregate structure conformation, statistical analysis indicated that this did not occur for the studied conditions. The results show that the technique and experimental conditions employed here produce aggregates having a well-defined, reproducible structure. Copyright © 2011