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Sample records for agile development methods

  1. Agile Development Methods for Space Operations

    NASA Technical Reports Server (NTRS)

    Trimble, Jay; Webster, Chris

    2012-01-01

    Main stream industry software development practice has gone from a traditional waterfall process to agile iterative development that allows for fast response to customer inputs and produces higher quality software at lower cost. How can we, the space ops community, adopt state of the art software development practice, achieve greater productivity at lower cost, and maintain safe and effective space flight operations? At NASA Ames, we are developing Mission Control Technologies Software, in collaboration with Johnson Space Center (JSC) and, more recently, the Jet Propulsion Laboratory (JPL).

  2. Agile Software Development Methods: A Comparative Review1

    NASA Astrophysics Data System (ADS)

    Abrahamsson, Pekka; Oza, Nilay; Siponen, Mikko T.

    Although agile software development methods have caught the attention of software engineers and researchers worldwide, scientific research still remains quite scarce. The aim of this study is to order and make sense of the different agile approaches that have been proposed. This comparative review is performed from the standpoint of using the following features as the analytical perspectives: project management support, life-cycle coverage, type of practical guidance, adaptability in actual use, type of research objectives and existence of empirical evidence. The results show that agile software development methods cover, without offering any rationale, different phases of the software development life-cycle and that most of these methods fail to provide adequate project management support. Moreover, quite a few methods continue to offer little concrete guidance on how to use their solutions or how to adapt them in different development situations. Empirical evidence after ten years of application remains quite limited. Based on the results, new directions on agile methods are outlined.

  3. Agile Software Development

    ERIC Educational Resources Information Center

    Biju, Soly Mathew

    2008-01-01

    Many software development firms are now adopting the agile software development method. This method involves the customer at every level of software development, thus reducing the impact of change in the requirement at a later stage. In this article, the principles of the agile method for software development are explored and there is a focus on…

  4. Agile methods in biomedical software development: a multi-site experience report

    PubMed Central

    Kane, David W; Hohman, Moses M; Cerami, Ethan G; McCormick, Michael W; Kuhlmman, Karl F; Byrd, Jeff A

    2006-01-01

    Background Agile is an iterative approach to software development that relies on strong collaboration and automation to keep pace with dynamic environments. We have successfully used agile development approaches to create and maintain biomedical software, including software for bioinformatics. This paper reports on a qualitative study of our experiences using these methods. Results We have found that agile methods are well suited to the exploratory and iterative nature of scientific inquiry. They provide a robust framework for reproducing scientific results and for developing clinical support systems. The agile development approach also provides a model for collaboration between software engineers and researchers. We present our experience using agile methodologies in projects at six different biomedical software development organizations. The organizations include academic, commercial and government development teams, and included both bioinformatics and clinical support applications. We found that agile practices were a match for the needs of our biomedical projects and contributed to the success of our organizations. Conclusion We found that the agile development approach was a good fit for our organizations, and that these practices should be applicable and valuable to other biomedical software development efforts. Although we found differences in how agile methods were used, we were also able to identify a set of core practices that were common to all of the groups, and that could be a focus for others seeking to adopt these methods. PMID:16734914

  5. Developments in Agile Manufacturing

    SciTech Connect

    Clinesmith, M.G.

    1993-09-01

    As part of a project design initiative, Sandia National Laboratories and AlliedSignal Inc. Kansas City Division have joined efforts to develop a concurrent engineering capability for the manufacturing of complex precision components. The primary effort of this project, called Agile Manufacturing, is directed toward: (1) Understand the error associated with manufacturing and inspection. (2) Develop methods for correcting error. (3) Integrate diverse software technologies into a compatible process. The Agile Manufacturing System (AMS) is a system that integrates product design, manufacturing, and inspection into a closed loop, concurrent engineering process. The goal of developing the Agile Manufacturing System is to: (1) Optimize accuracy in manufacturing and inspection. (A) Use of softgage software for product evaluation. This will ensure ANSI Y14.5 compliance. (B) Establish and monitor bias between CMM and machine center. (C) Map probe deflection error and apply correction to inspection results. This applies to both on machine probing and CMM inspections. (D) Inspection process. (2) Compress the cycle time from product concept to production level manufacturing and verification. (3) Create a self-correcting process that feeds inspection results back into the machining process. (4) Link subordinate processes (cutting/probing path, softgage model, etc.) to the solid model definition.

  6. Cross Sectional Study of Agile Software Development Methods and Project Performance

    ERIC Educational Resources Information Center

    Lambert, Tracy

    2011-01-01

    Agile software development methods, characterized by delivering customer value via incremental and iterative time-boxed development processes, have moved into the mainstream of the Information Technology (IT) industry. However, despite a growing body of research which suggests that a predictive manufacturing approach, with big up-front…

  7. Agile

    NASA Technical Reports Server (NTRS)

    Trimble, Jay Phillip

    2013-01-01

    This is based on a previous talk on agile development. Methods for delivering software on a short cycle are described, including interactions with the customer, the affect on the team, and how to be more effective, streamlined and efficient.

  8. ISS Double-Gimbaled CMG Subsystem Simulation Using the Agile Development Method

    NASA Technical Reports Server (NTRS)

    Inampudi, Ravi

    2016-01-01

    This paper presents an evolutionary approach in simulating a cluster of 4 Control Moment Gyros (CMG) on the International Space Station (ISS) using a common sense approach (the agile development method) for concurrent mathematical modeling and simulation of the CMG subsystem. This simulation is part of Training systems for the 21st Century simulator which will provide training for crew members, instructors, and flight controllers. The basic idea of how the CMGs on the space station are used for its non-propulsive attitude control is briefly explained to set up the context for simulating a CMG subsystem. Next different reference frames and the detailed equations of motion (EOM) for multiple double-gimbal variable-speed control moment gyroscopes (DGVs) are presented. Fixing some of the terms in the EOM becomes the special case EOM for ISS's double-gimbaled fixed speed CMGs. CMG simulation development using the agile development method is presented in which customer's requirements and solutions evolve through iterative analysis, design, coding, unit testing and acceptance testing. At the end of the iteration a set of features implemented in that iteration are demonstrated to the flight controllers thus creating a short feedback loop and helping in creating adaptive development cycles. The unified modeling language (UML) tool is used in illustrating the user stories, class designs and sequence diagrams. This incremental development approach of mathematical modeling and simulating the CMG subsystem involved the development team and the customer early on, thus improving the quality of the working CMG system in each iteration and helping the team to accurately predict the cost, schedule and delivery of the software.

  9. Introduction to Stand-up Meetings in Agile Methods

    NASA Astrophysics Data System (ADS)

    Hasnain, Eisha; Hall, Tracy

    2009-05-01

    In recent years, agile methods have become more popular in the software industry. Agile methods are a new approach compared to plan-driven approaches. One of the most important shifts in adopting an agile approach is the central focus given to people in the process. This is exemplified by the independence afforded to developers in the development work they do. This work investigates the opinions of practitioners about daily stand-up meetings in the agile methods and the role of developer in that. For our investigation we joined a yahoo group called "Extreme Programming". Our investigation suggests that although trust is an important factor in agile methods. But stand-ups are not the place to build trust.

  10. Agile Methods for Open Source Safety-Critical Software

    PubMed Central

    Enquobahrie, Andinet; Ibanez, Luis; Cheng, Patrick; Yaniv, Ziv; Cleary, Kevin; Kokoori, Shylaja; Muffih, Benjamin; Heidenreich, John

    2011-01-01

    The introduction of software technology in a life-dependent environment requires the development team to execute a process that ensures a high level of software reliability and correctness. Despite their popularity, agile methods are generally assumed to be inappropriate as a process family in these environments due to their lack of emphasis on documentation, traceability, and other formal techniques. Agile methods, notably Scrum, favor empirical process control, or small constant adjustments in a tight feedback loop. This paper challenges the assumption that agile methods are inappropriate for safety-critical software development. Agile methods are flexible enough to encourage the right amount of ceremony; therefore if safety-critical systems require greater emphasis on activities like formal specification and requirements management, then an agile process will include these as necessary activities. Furthermore, agile methods focus more on continuous process management and code-level quality than classic software engineering process models. We present our experiences on the image-guided surgical toolkit (IGSTK) project as a backdrop. IGSTK is an open source software project employing agile practices since 2004. We started with the assumption that a lighter process is better, focused on evolving code, and only adding process elements as the need arose. IGSTK has been adopted by teaching hospitals and research labs, and used for clinical trials. Agile methods have matured since the academic community suggested they are not suitable for safety-critical systems almost a decade ago, we present our experiences as a case study for renewing the discussion. PMID:21799545

  11. Agile Methods for Open Source Safety-Critical Software.

    PubMed

    Gary, Kevin; Enquobahrie, Andinet; Ibanez, Luis; Cheng, Patrick; Yaniv, Ziv; Cleary, Kevin; Kokoori, Shylaja; Muffih, Benjamin; Heidenreich, John

    2011-08-01

    The introduction of software technology in a life-dependent environment requires the development team to execute a process that ensures a high level of software reliability and correctness. Despite their popularity, agile methods are generally assumed to be inappropriate as a process family in these environments due to their lack of emphasis on documentation, traceability, and other formal techniques. Agile methods, notably Scrum, favor empirical process control, or small constant adjustments in a tight feedback loop. This paper challenges the assumption that agile methods are inappropriate for safety-critical software development. Agile methods are flexible enough to encourage the rightamount of ceremony; therefore if safety-critical systems require greater emphasis on activities like formal specification and requirements management, then an agile process will include these as necessary activities. Furthermore, agile methods focus more on continuous process management and code-level quality than classic software engineering process models. We present our experiences on the image-guided surgical toolkit (IGSTK) project as a backdrop. IGSTK is an open source software project employing agile practices since 2004. We started with the assumption that a lighter process is better, focused on evolving code, and only adding process elements as the need arose. IGSTK has been adopted by teaching hospitals and research labs, and used for clinical trials. Agile methods have matured since the academic community suggested they are not suitable for safety-critical systems almost a decade ago, we present our experiences as a case study for renewing the discussion. PMID:21799545

  12. A Roadmap for Using Agile Development in a Traditional Environment

    NASA Technical Reports Server (NTRS)

    Streiffert, Barbara; Starbird, Thomas; Grenander, Sven

    2006-01-01

    One of the newer classes of software engineering techniques is called 'Agile Development'. In Agile Development software engineers take small implementation steps and, in some cases, they program in pairs. In addition, they develop automatic tests prior to implementing their small functional piece. Agile Development focuses on rapid turnaround, incremental planning, customer involvement and continuous integration. Agile Development is not the traditional waterfall method or even a rapid prototyping method (although this methodology is closer to Agile Development). At the Jet Propulsion Laboratory (JPL) a few groups have begun Agile Development software implementations. The difficulty with this approach becomes apparent when Agile Development is used in an organization that has specific criteria and requirements handed down for how software development is to be performed. The work at the JPL is performed for the National Aeronautics and Space Agency (NASA). Both organizations have specific requirements, rules and processes for developing software. This paper will discuss some of the initial uses of the Agile Development methodology, the spread of this method and the current status of the successful incorporation into the current JPL development policies and processes.

  13. A Roadmap for Using Agile Development in a Traditional Environment

    NASA Technical Reports Server (NTRS)

    Streiffert, Barbara A.; Starbird, Thomas; Grenander, Sven

    2006-01-01

    One of the newer classes of software engineering techniques is called 'Agile Development'. In Agile Development software engineers take small implementation steps and, in some cases they program in pairs. In addition, they develop automatic tests prior to implementing their small functional piece. Agile Development focuses on rapid turnaround, incremental planning, customer involvement and continuous integration. Agile Development is not the traditional waterfall method or even a rapid prototyping method (although this methodology is closer to Agile Development). At Jet Propulsion Laboratory (JPL) a few groups have begun Agile Development software implementations. The difficulty with this approach becomes apparent when Agile Development is used in an organization that has specific criteria and requirements handed down for how software development is to be performed. The work at the JPL is performed for the National Aeronautics and Space Agency (NASA). Both organizations have specific requirements, rules and procedure for developing software. This paper will discuss the some of the initial uses of the Agile Development methodology, the spread of this method and the current status of the successful incorporation into the current JPL development policies.

  14. Teaching Agile Software Development: A Case Study

    ERIC Educational Resources Information Center

    Devedzic, V.; Milenkovic, S. R.

    2011-01-01

    This paper describes the authors' experience of teaching agile software development to students of computer science, software engineering, and other related disciplines, and comments on the implications of this and the lessons learned. It is based on the authors' eight years of experience in teaching agile software methodologies to various groups…

  15. A Case Study of Coordination in Distributed Agile Software Development

    NASA Astrophysics Data System (ADS)

    Hole, Steinar; Moe, Nils Brede

    Global Software Development (GSD) has gained significant popularity as an emerging paradigm. Companies also show interest in applying agile approaches in distributed development to combine the advantages of both approaches. However, in their most radical forms, agile and GSD can be placed in each end of a plan-based/agile spectrum because of how work is coordinated. We describe how three GSD projects applying agile methods coordinate their work. We found that trust is needed to reduce the need of standardization and direct supervision when coordinating work in a GSD project, and that electronic chatting supports mutual adjustment. Further, co-location and modularization mitigates communication problems, enables agility in at least part of a GSD project, and renders the implementation of Scrum of Scrums possible.

  16. Developing communications requirements for Agile Product Realization

    SciTech Connect

    Forsythe, C.; Ashby, M.R.

    1994-03-01

    Sandia National Laboratories has undertaken the Agile Product Realization for Innovative electroMEchanical Devices (A-PRIMED) pilot project to develop and implement technologies for agile design and manufacturing of electrochemical components. Emphasis on information-driven processes, concurrent engineering and multi-functional team communications makes computer-supported cooperative work critical to achieving significantly faster product development cycles. This report describes analyses conducted in developing communications requirements and a communications plan that addresses the unique communications demands of an agile enterprise.

  17. Modern Enterprise Systems as Enablers of Agile Development

    NASA Astrophysics Data System (ADS)

    Fredriksson, Odd; Ljung, Lennart

    Traditional ES technology and traditional project management methods are supporting and matching each other. But they are not supporting the critical success conditions for ES development in an effective way. Although the findings from one case study of a successful modern ES change project is not strong empirical evidence, we carefully propose that the new modern ES technology is supporting and matching agile project management methods. In other words, it provides the required flexibility which makes it possible to put into practice the agile way of running projects, both for the system supplier and for the customer. In addition, we propose that the combination of modern ES technology and agile project management methods are more appropriate for supporting the realization of critical success conditions for ES development. The main purpose of this chapter is to compare critical success conditions for modern enterprise systems development projects with critical success conditions for agile information systems development projects.

  18. Agile informatics: application of agile project management to the development of a personal health application.

    PubMed

    Chung, Jeanhee; Pankey, Evan; Norris, Ryan J

    2007-01-01

    We describe the application of the Agile method-- a short iteration cycle, user responsive, measurable software development approach-- to the project management of a modular personal health record, iHealthSpace, to be deployed to the patients and providers of a large academic primary care practice. PMID:18694014

  19. Project-Method Fit: Exploring Factors That Influence Agile Method Use

    ERIC Educational Resources Information Center

    Young, Diana K.

    2013-01-01

    While the productivity and quality implications of agile software development methods (SDMs) have been demonstrated, research concerning the project contexts where their use is most appropriate has yielded less definitive results. Most experts agree that agile SDMs are not suited for all project contexts. Several project and team factors have been…

  20. Architecture-Centric Methods and Agile Approaches

    NASA Astrophysics Data System (ADS)

    Babar, Muhammad Ali; Abrahamsson, Pekka

    Agile software development approaches have had significant impact on industrial software development practices. Despite becoming widely popular, there is an increasing perplexity about the role and importance of a system’s software architecture in agile approaches [1, 2]. Advocates of the vital role of architecture in achieving quality goals of large-scale-software-intensive-systems are skeptics of the scalability of any development approach that does not pay sufficient attention to architectural issues. However, the proponents of agile approaches usually perceive the upfront design and evaluation of architecture as being of less value to the customers of a system. According to them, for example, re-factoring can help fix most of the problems. Many experiences show that large-scale re-factoring often results in significant defects, which are very costly to address later in the development cycle. It is considered that re-factoring is worthwhile as long as the high-level design is good enough to limit the need for large-scale re-factoring [1, 3, 4].

  1. Creativity in Agile Systems Development: A Literature Review

    NASA Astrophysics Data System (ADS)

    Conboy, Kieran; Wang, Xiaofeng; Fitzgerald, Brian

    Proponents of agile methods claim that enabling, fostering and driving creativity is the key motivation that differentiates agile methods from their more traditional, beauraucratic counterparts. However, there is very little rigorous research to support this claim. Like most of their predecessors, the development and promotion of these methods has been almost entirely driven by practitioners and consultants, with little objective validation from the research community. This lack of validation is particularly relevant for SMEs, given that many of their project teams typify the environment to which agile methods are most suited i.e. small, co-located teams with diverse, blended skills in unstructured, sometimes even chaotic surroundings. This paper uses creativity theory as a lens to review the current agile method literature to understand exactly how much we know about the extent to which creativity actually occurs in these agile environments. The study reveals many gaps and conflict of opinion in the body of knowledge in its current state and identifies many avenues for further research.

  2. The Impacts of Agile Development Methodology Use on Project Success: A Contingency View

    ERIC Educational Resources Information Center

    Tripp, John F.

    2012-01-01

    Agile Information Systems Development Methods have emerged in the past decade as an alternative manner of managing the work and delivery of information systems development teams, with a large number of organizations reporting the adoption & use of agile methods. The practitioners of these methods make broad claims as to the benefits of their…

  3. Towards a Framework for Using Agile Approaches in Global Software Development

    NASA Astrophysics Data System (ADS)

    Hossain, Emam; Ali Babar, Muhammad; Verner, June

    As agile methods and Global Software Development (GSD) are become increasingly popular, GSD project managers have been exploring the viability of using agile approaches in their development environments. Despite the expected benefits of using an agile approach with a GSD project, the overall combining mechanisms of the two approaches are not clearly understood. To address this challenge, we propose a conceptual framework, based on the research literature. This framework is expected to aid a project manager in deciding what agile strategies are effective for a particular GSD project, taking into account project context. We use an industry-based case study to explore the components of our conceptual framework. Our case study is planned and conducted according to specific published case study guidelines. We identify the agile practices and agile supporting practices used by a GSD project manager in our case study and conclude with future research directions.

  4. Parallel optimization methods for agile manufacturing

    SciTech Connect

    Meza, J.C.; Moen, C.D.; Plantenga, T.D.; Spence, P.A.; Tong, C.H.; Hendrickson, B.A.; Leland, R.W.; Reese, G.M.

    1997-08-01

    The rapid and optimal design of new goods is essential for meeting national objectives in advanced manufacturing. Currently almost all manufacturing procedures involve the determination of some optimal design parameters. This process is iterative in nature and because it is usually done manually it can be expensive and time consuming. This report describes the results of an LDRD, the goal of which was to develop optimization algorithms and software tools that will enable automated design thereby allowing for agile manufacturing. Although the design processes vary across industries, many of the mathematical characteristics of the problems are the same, including large-scale, noisy, and non-differentiable functions with nonlinear constraints. This report describes the development of a common set of optimization tools using object-oriented programming techniques that can be applied to these types of problems. The authors give examples of several applications that are representative of design problems including an inverse scattering problem, a vibration isolation problem, a system identification problem for the correlation of finite element models with test data and the control of a chemical vapor deposition reactor furnace. Because the function evaluations are computationally expensive, they emphasize algorithms that can be adapted to parallel computers.

  5. Supporting Agile Development of Authorization Rules for SME Applications

    NASA Astrophysics Data System (ADS)

    Bartsch, Steffen; Sohr, Karsten; Bormann, Carsten

    Custom SME applications for collaboration and workflow have become affordable when implemented as Web applications employing Agile methodologies. Security engineering is still difficult with Agile development, though: heavy-weight processes put the improvements of Agile development at risk. We propose Agile security engineering and increased end-user involvement to improve Agile development with respect to authorization policy development. To support the authorization policy development, we introduce a simple and readable authorization rules language implemented in a Ruby on Rails authorization plugin that is employed in a real-world SME collaboration and workflow application. Also, we report on early findings of the language’s use in authorization policy development with domain experts.

  6. Peridigm summary report : lessons learned in development with agile components.

    SciTech Connect

    Salinger, Andrew Gerhard; Mitchell, John Anthony; Littlewood, David John; Parks, Michael L.

    2011-09-01

    This report details efforts to deploy Agile Components for rapid development of a peridynamics code, Peridigm. The goal of Agile Components is to enable the efficient development of production-quality software by providing a well-defined, unifying interface to a powerful set of component-based software. Specifically, Agile Components facilitate interoperability among packages within the Trilinos Project, including data management, time integration, uncertainty quantification, and optimization. Development of the Peridigm code served as a testbed for Agile Components and resulted in a number of recommendations for future development. Agile Components successfully enabled rapid integration of Trilinos packages into Peridigm. A cost of this approach, however, was a set of restrictions on Peridigm's architecture which impacted the ability to track history-dependent material data, dynamically modify the model discretization, and interject user-defined routines into the time integration algorithm. These restrictions resulted in modifications to the Agile Components approach, as implemented in Peridigm, and in a set of recommendations for future Agile Components development. Specific recommendations include improved handling of material states, a more flexible flow control model, and improved documentation. A demonstration mini-application, SimpleODE, was developed at the onset of this project and is offered as a potential supplement to Agile Components documentation.

  7. Future Research in Agile Systems Development: Applying Open Innovation Principles Within the Agile Organisation

    NASA Astrophysics Data System (ADS)

    Conboy, Kieran; Morgan, Lorraine

    A particular strength of agile approaches is that they move away from ‘introverted' development and intimately involve the customer in all areas of development, supposedly leading to the development of a more innovative and hence more valuable information system. However, we argue that a single customer representative is too narrow a focus to adopt and that involvement of stakeholders beyond the software development itself is still often quite weak and in some cases non-existent. In response, we argue that current thinking regarding innovation in agile development needs to be extended to include multiple stakeholders outside the business unit. This paper explores the intra-organisational applicability and implications of open innovation in agile systems development. Additionally, it argues for a different perspective of project management that includes collaboration and knowledge-sharing with other business units, customers, partners, and other relevant stakeholders pertinent to the business success of an organisation, thus embracing open innovation principles.

  8. Distributed agile software development for the SKA

    NASA Astrophysics Data System (ADS)

    Wicenec, Andreas; Parsons, Rebecca; Kitaeff, Slava; Vinsen, Kevin; Wu, Chen; Nelson, Paul; Reed, David

    2012-09-01

    The SKA software will most probably be developed by many groups distributed across the globe and coming from dierent backgrounds, like industries and research institutions. The SKA software subsystems will have to cover a very wide range of dierent areas, but still they have to react and work together like a single system to achieve the scientic goals and satisfy the challenging data ow requirements. Designing and developing such a system in a distributed fashion requires proper tools and the setup of an environment to allow for ecient detection and tracking of interface and integration issues in particular in a timely way. Agile development can provide much faster feedback mechanisms and also much tighter collaboration between the customer (scientist) and the developer. Continuous integration and continuous deployment on the other hand can provide much faster feedback of integration issues from the system level to the subsystem developers. This paper describes the results obtained from trialing a potential SKA development environment based on existing science software development processes like ALMA, the expected distribution of the groups potentially involved in the SKA development and experience gained in the development of large scale commercial software projects.

  9. Development of an agility assessment module for preliminary fighter design

    NASA Technical Reports Server (NTRS)

    Ngan, Angelen; Bauer, Brent; Biezad, Daniel; Hahn, Andrew

    1996-01-01

    A FORTRAN computer program is presented to perform agility analysis on fighter aircraft configurations. This code is one of the modules of the NASA Ames ACSYNT (AirCraft SYNThesis) design code. The background of the agility research in the aircraft industry and a survey of a few agility metrics are discussed. The methodology, techniques, and models developed for the code are presented. FORTRAN programs were developed for two specific metrics, CCT (Combat Cycle Time) and PM (Pointing Margin), as part of the agility module. The validity of the code was evaluated by comparing with existing flight test data. Example trade studies using the agility module along with ACSYNT were conducted using Northrop F-20 Tigershark and McDonnell Douglas F/A-18 Hornet aircraft models. The sensitivity of thrust loading and wing loading on agility criteria were investigated. The module can compare the agility potential between different configurations and has the capability to optimize agility performance in the preliminary design process. This research provides a new and useful design tool for analyzing fighter performance during air combat engagements.

  10. Balancing Plan-Driven and Agile Methods in Software Engineering Project Courses

    NASA Astrophysics Data System (ADS)

    Boehm, Barry; Port, Dan; Winsor Brown, A.

    2002-09-01

    For the past 6 years, we have been teaching a two-semester software engineering project course. The students organize into 5-person teams and develop largely web-based electronic services projects for real USC campus clients. We have been using and evolving a method called Model- Based (System) Architecting and Software Engineering (MBASE) for use in both the course and in industrial applications. The MBASE Guidelines include a lot of documents. We teach risk-driven documentation: if it is risky to document something, and not risky to leave it out (e.g., GUI screen placements), leave it out. Even so, students tend to associate more documentation with higher grades, although our grading eventually discourages this. We are always on the lookout for ways to have students learn best practices without having to produce excessive documentation. Thus, we were very interested in analyzing the various emerging agile methods. We found that agile methods and milestone plan-driven methods are part of a “how much planning is enough?” spectrum. Both agile and plan-driven methods have home grounds of project characteristics where they clearly work best, and where the other will have difficulties. Hybrid agile/plan-driven approaches are feasible, and necessary for projects having a mix of agile and plan-driven home ground characteristics. Information technology trends are going more toward the agile methods' home ground characteristics of emergent requirements and rapid change, although there is a concurrent increase in concern with dependability. As a result, we are currently experimenting with risk-driven combinations of MBASE and agile methods, such as integrating requirements, test plans, peer reviews, and pair programming into “agile quality management.”

  11. Chaste: using agile programming techniques to develop computational biology software.

    PubMed

    Pitt-Francis, Joe; Bernabeu, Miguel O; Cooper, Jonathan; Garny, Alan; Momtahan, Lee; Osborne, James; Pathmanathan, Pras; Rodriguez, Blanca; Whiteley, Jonathan P; Gavaghan, David J

    2008-09-13

    Cardiac modelling is the area of physiome modelling where the available simulation software is perhaps most mature, and it therefore provides an excellent starting point for considering the software requirements for the wider physiome community. In this paper, we will begin by introducing some of the most advanced existing software packages for simulating cardiac electrical activity. We consider the software development methods used in producing codes of this type, and discuss their use of numerical algorithms, relative computational efficiency, usability, robustness and extensibility. We then go on to describe a class of software development methodologies known as test-driven agile methods and argue that such methods are more suitable for scientific software development than the traditional academic approaches. A case study is a project of our own, Cancer, Heart and Soft Tissue Environment, which is a library of computational biology software that began as an experiment in the use of agile programming methods. We present our experiences with a review of our progress thus far, focusing on the advantages and disadvantages of this new approach compared with the development methods used in some existing packages. We conclude by considering whether the likely wider needs of the cardiac modelling community are currently being met and suggest that, in order to respond effectively to changing requirements, it is essential that these codes should be more malleable. Such codes will allow for reliable extensions to include both detailed mathematical models--of the heart and other organs--and more efficient numerical techniques that are currently being developed by many research groups worldwide. PMID:18565813

  12. Lean and Agile Development of the AITS Ground Software System

    NASA Astrophysics Data System (ADS)

    Richters, Mark; Dutruel, Etienne; Mecredy, Nicolas

    2013-08-01

    We present the ongoing development of a new ground software system used for integrating, testing and operating spacecraft. The Advanced Integration and Test Services (AITS) project aims at providing a solution for electrical ground support equipment and mission control systems in future Astrium Space Transportation missions. Traditionally ESA ground or flight software development projects are conducted according to a waterfall-like process as specified in the ECSS-E-40 standard promoted by ESA in the European industry. In AITS a decision was taken to adopt an agile development process. This work could serve as a reference for future ESA software projects willing to apply agile concepts.

  13. Adopting best practices: "Agility" moves from software development to healthcare project management.

    PubMed

    Kitzmiller, Rebecca; Hunt, Eleanor; Sproat, Sara Breckenridge

    2006-01-01

    It is time for a change in mindset in how nurses operationalize system implementations and manage projects. Computers and systems have evolved over time from unwieldy mysterious machines of the past to ubiquitous computer use in every aspect of daily lives and work sites. Yet, disconcertingly, the process used to implement these systems has not evolved. Technology implementation does not need to be a struggle. It is time to adapt traditional plan-driven implementation methods to incorporate agile techniques. Agility is a concept borrowed from software development and is presented here because it encourages flexibility, adaptation, and continuous learning as part of the implementation process. Agility values communication and harnesses change to an advantage, which facilitates the natural evolution of an adaptable implementation process. Specific examples of agility in an implementation are described, and plan-driven implementation stages are adapted to incorporate relevant agile techniques. This comparison demonstrates how an agile approach enhances traditional implementation techniques to meet the demands of today's complex healthcare environments. PMID:16554690

  14. A Capstone Course on Agile Software Development Using Scrum

    ERIC Educational Resources Information Center

    Mahnic, V.

    2012-01-01

    In this paper, an undergraduate capstone course in software engineering is described that not only exposes students to agile software development, but also makes it possible to observe the behavior of developers using Scrum for the first time. The course requires students to work as Scrum Teams, responsible for the implementation of a set of user…

  15. Impact of Agile Software Development Model on Software Maintainability

    ERIC Educational Resources Information Center

    Gawali, Ajay R.

    2012-01-01

    Software maintenance and support costs account for up to 60% of the overall software life cycle cost and often burdens tightly budgeted information technology (IT) organizations. Agile software development approach delivers business value early, but implications on software maintainability are still unknown. The purpose of this quantitative study…

  16. Agile enterprise development framework utilizing services principles for building pervasive security

    NASA Astrophysics Data System (ADS)

    Farroha, Deborah; Farroha, Bassam

    2011-06-01

    We are in an environment of continuously changing mission requirements and therefore our Information Systems must adapt to accomplish new tasks, quicker, in a more proficient manner. Agility is the only way we will be able to keep up with this change. But there are subtleties that must be considered as we adopt various agile methods: secure, protect, control and authenticate are all elements needed to posture our Information Technology systems to counteract the real and perceived threats in today's environment. Many systems have been tasked to ingest process and analyze different data sets than they were originally designed for and they have to interact with multiple new systems that were unaccounted for at design time. Leveraging the tenets of security, we have devised a new framework that takes agility into a new realm where the product will built to work in a service-based environment but is developed using agile processes. Even though these two criteria promise to hone the development effort, they actually contradict each other in philosophy where Services require stable interfaces, while Agile focuses on being flexible and tolerate changes up to much later stages of development. This framework is focused on enabling a successful product development that capitalizes on both philosophies.

  17. Development of a Computer Program for Analyzing Preliminary Aircraft Configurations in Relationship to Emerging Agility Metrics

    NASA Technical Reports Server (NTRS)

    Bauer, Brent

    1993-01-01

    This paper discusses the development of a FORTRAN computer code to perform agility analysis on aircraft configurations. This code is to be part of the NASA-Ames ACSYNT (AirCraft SYNThesis) design code. This paper begins with a discussion of contemporary agility research in the aircraft industry and a survey of a few agility metrics. The methodology, techniques and models developed for the code are then presented. Finally, example trade studies using the agility module along with ACSYNT are illustrated. These trade studies were conducted using a Northrop F-20 Tigershark aircraft model. The studies show that the agility module is effective in analyzing the influence of common parameters such as thrust-to-weight ratio and wing loading on agility criteria. The module can compare the agility potential between different configurations. In addition, one study illustrates the module's ability to optimize a configuration's agility performance.

  18. A Roadmap for using Agile Development in a Traditional System

    NASA Technical Reports Server (NTRS)

    Streiffert, Barbara; Starbird, Thomas

    2006-01-01

    I. Ensemble Development Group: a) Produces activity planning software for in spacecraft; b) Built on Eclipse Rich Client Platform (open source development and runtime software); c) Funded by multiple sources including the Mars Technology Program; d) Incorporated the use of Agile Development. II. Next Generation Uplink Planning System: a) Researches the Activity Planning and Sequencing Subsystem for Mars Science Laboratory (APSS); b) APSS includes Ensemble, Activity Modeling, Constraint Checking, Command Editing and Sequencing tools plus other uplink generation utilities; c) Funded by the Mars Technology Program; d) Integrates all of the tools for APSS.

  19. Development of EarthCube Governance: An Agile Approach

    NASA Astrophysics Data System (ADS)

    Pearthree, G.; Allison, M. L.; Patten, K.

    2013-12-01

    Governance of geosciences cyberinfrastructure is a complex and essential undertaking, critical in enabling distributed knowledge communities to collaborate and communicate across disciplines, distances, and cultures. Advancing science with respect to 'grand challenges," such as global climate change, weather prediction, and core fundamental science, depends not just on technical cyber systems, but also on social systems for strategic planning, decision-making, project management, learning, teaching, and building a community of practice. Simply put, a robust, agile technical system depends on an equally robust and agile social system. Cyberinfrastructure development is wrapped in social, organizational and governance challenges, which may significantly impede progress. An agile development process is underway for governance of transformative investments in geosciences cyberinfrastructure through the NSF EarthCube initiative. Agile development is iterative and incremental, and promotes adaptive planning and rapid and flexible response. Such iterative deployment across a variety of EarthCube stakeholders encourages transparency, consensus, accountability, and inclusiveness. A project Secretariat acts as the coordinating body, carrying out duties for planning, organizing, communicating, and reporting. A broad coalition of stakeholder groups comprises an Assembly (Mainstream Scientists, Cyberinfrastructure Institutions, Information Technology/Computer Sciences, NSF EarthCube Investigators, Science Communities, EarthCube End-User Workshop Organizers, Professional Societies) to serve as a preliminary venue for identifying, evaluating, and testing potential governance models. To offer opportunity for broader end-user input, a crowd-source approach will engage stakeholders not involved otherwise. An Advisory Committee from the Earth, ocean, atmosphere, social, computer and library sciences is guiding the process from a high-level policy point of view. Developmental

  20. An Investigation of Agility Issues in Scrum Teams Using Agility Indicators

    NASA Astrophysics Data System (ADS)

    Pikkarainen, Minna; Wang, Xiaofeng

    Agile software development methods have emerged and become increasingly popular in recent years; yet the issues encountered by software development teams that strive to achieve agility using agile methods are yet to be explored systematically. Built upon a previous study that has established a set of indicators of agility, this study investigates what issues are manifested in software development teams using agile methods. It is focussed on Scrum teams particularly. In other words, the goal of the chapter is to evaluate Scrum teams using agility indicators and therefore to further validate previously presented agility indicators within the additional cases. A multiple case study research method is employed. The findings of the study reveal that the teams using Scrum do not necessarily achieve agility in terms of team autonomy, sharing, stability and embraced uncertainty. The possible reasons include previous organizational plan-driven culture, resistance towards the Scrum roles and changing resources.

  1. How Can Agile Practices Minimize Global Software Development Co-ordination Risks?

    NASA Astrophysics Data System (ADS)

    Hossain, Emam; Babar, Muhammad Ali; Verner, June

    The distribution of project stakeholders in Global Software Development (GSD) projects provides significant risks related to project communication, coordination and control processes. There is growing interest in applying agile practices in GSD projects in order to leverage the advantages of both approaches. In some cases, GSD project managers use agile practices to reduce project distribution challenges. We use an existing coordination framework to identify GSD coordination problems due to temporal, geographical and socio-cultural distances. An industry-based case study is used to describe, explore and explain the use of agile practices to reduce development coordination challenges.

  2. Optical flows method for lightweight agile remote sensor design and instrumentation

    NASA Astrophysics Data System (ADS)

    Wang, Chong; Xing, Fei; Wang, Hongjian; You, Zheng

    2013-08-01

    Lightweight agile remote sensors have become one type of the most important payloads and were widely utilized in space reconnaissance and resource survey. These imaging sensors are designed to obtain the high spatial, temporary and spectral resolution imageries. Key techniques in instrumentation include flexible maneuvering, advanced imaging control algorithms and integrative measuring techniques, which are closely correlative or even acting as the bottle-necks for each other. Therefore, mutual restrictive problems must be solved and optimized. Optical flow is the critical model which to be fully represented in the information transferring as well as radiation energy flowing in dynamic imaging. For agile sensors, especially with wide-field-of view, imaging optical flows may distort and deviate seriously when they perform large angle attitude maneuvering imaging. The phenomena are mainly attributed to the geometrical characteristics of the three-dimensional earth surface as well as the coupled effects due to the complicated relative motion between the sensor and scene. Under this circumstance, velocity fields distribute nonlinearly, the imageries may badly be smeared or probably the geometrical structures are changed since the image velocity matching errors are not having been eliminated perfectly. In this paper, precise imaging optical flow model is established for agile remote sensors, for which optical flows evolving is factorized by two forms, which respectively due to translational movement and image shape changing. Moreover, base on that, agile remote sensors instrumentation was investigated. The main techniques which concern optical flow modeling include integrative design with lightweight star sensors along with micro inertial measurement units and corresponding data fusion, the assemblies of focal plane layout and control, imageries post processing for agile remote sensors etc. Some experiments show that the optical analyzing method is effective to

  3. Assessment of proposed fighter agility metrics

    NASA Technical Reports Server (NTRS)

    Liefer, Randall K.; Valasek, John; Eggold, David P.; Downing, David R.

    1990-01-01

    This paper presents the results of an analysis of proposed metrics to assess fighter aircraft agility. A novel framework for classifying these metrics is developed and applied. A set of transient metrics intended to quantify the axial and pitch agility of fighter aircraft is evaluated with a high fidelity, nonlinear F-18 simulation. Test techniques and data reduction method are proposed, and sensitivities to pilot introduced errors during flight testing is investigated. Results indicate that the power onset and power loss parameters are promising candidates for quantifying axial agility, while maximum pitch up and pitch down rates are for quantifying pitch agility.

  4. Developing a model for agile supply: an empirical study from Iranian pharmaceutical supply chain.

    PubMed

    Rajabzadeh Ghatari, Ali; Mehralian, Gholamhossein; Zarenezhad, Forouzandeh; Rasekh, Hamid Reza

    2013-01-01

    Agility is the fundamental characteristic of a supply chain needed for survival in turbulent markets, where environmental forces create additional uncertainty resulting in higher risk in the supply chain management. In addition, agility helps providing the right product, at the right time to the consumer. The main goal of this research is therefore to promote supplier selection in pharmaceutical industry according to the formative basic factors. Moreover, this paper can configure its supply network to achieve the agile supply chain. The present article analyzes the supply part of supply chain based on SCOR model, used to assess agile supply chains by highlighting their specific characteristics and applicability in providing the active pharmaceutical ingredient (API). This methodology provides an analytical modeling; the model enables potential suppliers to be assessed against the multiple criteria using both quantitative and qualitative measures. In addition, for making priority of critical factors, TOPSIS algorithm has been used as a common technique of MADM model. Finally, several factors such as delivery speed, planning and reorder segmentation, trust development and material quantity adjustment are identified and prioritized as critical factors for being agile in supply of API. PMID:24250689

  5. Developing a Model for Agile Supply: an Empirical Study from Iranian Pharmaceutical Supply Chain

    PubMed Central

    Rajabzadeh Ghatari, Ali; Mehralian, Gholamhossein; Zarenezhad, Forouzandeh; Rasekh, Hamid Reza

    2013-01-01

    Agility is the fundamental characteristic of a supply chain needed for survival in turbulent markets, where environmental forces create additional uncertainty resulting in higher risk in the supply chain management. In addition, agility helps providing the right product, at the right time to the consumer. The main goal of this research is therefore to promote supplier selection in pharmaceutical industry according to the formative basic factors. Moreover, this paper can configure its supply network to achieve the agile supply chain. The present article analyzes the supply part of supply chain based on SCOR model, used to assess agile supply chains by highlighting their specific characteristics and applicability in providing the active pharmaceutical ingredient (API). This methodology provides an analytical modeling; the model enables potential suppliers to be assessed against the multiple criteria using both quantitative and qualitative measures. In addition, for making priority of critical factors, TOPSIS algorithm has been used as a common technique of MADM model. Finally, several factors such as delivery speed, planning and reorder segmentation, trust development and material quantity adjustment are identified and prioritized as critical factors for being agile in supply of API. PMID:24250689

  6. Organizational Agility and Complex Enterprise System Innovations: A Mixed Methods Study of the Effects of Enterprise Systems on Organizational Agility

    ERIC Educational Resources Information Center

    Kharabe, Amol T.

    2012-01-01

    Over the last two decades, firms have operated in "increasingly" accelerated "high-velocity" dynamic markets, which require them to become "agile." During the same time frame, firms have increasingly deployed complex enterprise systems--large-scale packaged software "innovations" that integrate and automate…

  7. An Agile Course-Delivery Approach

    ERIC Educational Resources Information Center

    Capellan, Mirkeya

    2009-01-01

    In the world of software development, agile methodologies have gained popularity thanks to their lightweight methodologies and flexible approach. Many advocates believe that agile methodologies can provide significant benefits if applied in the educational environment as a teaching method. The need for an approach that engages and motivates…

  8. Some Findings Concerning Requirements in Agile Methodologies

    NASA Astrophysics Data System (ADS)

    Rodríguez, Pilar; Yagüe, Agustín; Alarcón, Pedro P.; Garbajosa, Juan

    Agile methods have appeared as an attractive alternative to conventional methodologies. These methods try to reduce the time to market and, indirectly, the cost of the product through flexible development and deep customer involvement. The processes related to requirements have been extensively studied in literature, in most cases in the frame of conventional methods. However, conclusions of conventional methodologies could not be necessarily valid for Agile; in some issues, conventional and Agile processes are radically different. As recent surveys report, inadequate project requirements is one of the most conflictive issues in agile approaches and better understanding about this is needed. This paper describes some findings concerning requirements activities in a project developed under an agile methodology. The project intended to evolve an existing product and, therefore, some background information was available. The major difficulties encountered were related to non-functional needs and management of requirements dependencies.

  9. Agile in Large-Scale Development Workshop: Coaching, Transitioning and Practicing

    NASA Astrophysics Data System (ADS)

    Nilsson, Thomas; Larsson, Andreas

    Agile in large-scale and complex development presents its own set of problems, both how to practice, transition and coaching. This workshop aims at bringing persons interested in this topic together to share tools, techniques and insights. The workshop will follow the increasingly popular “lightning talk + open space” format.

  10. Applying Agile MethodstoWeapon/Weapon-Related Software

    SciTech Connect

    Adams, D; Armendariz, M; Blackledge, M; Campbell, F; Cloninger, M; Cox, L; Davis, J; Elliott, M; Granger, K; Hans, S; Kuhn, C; Lackner, M; Loo, P; Matthews, S; Morrell, K; Owens, C; Peercy, D; Pope, G; Quirk, R; Schilling, D; Stewart, A; Tran, A; Ward, R; Williamson, M

    2007-05-02

    This white paper provides information and guidance to the Department of Energy (DOE) sites on Agile software development methods and the impact of their application on weapon/weapon-related software development. The purpose of this white paper is to provide an overview of Agile methods, examine the accepted interpretations/uses/practices of these methodologies, and discuss the applicability of Agile methods with respect to Nuclear Weapons Complex (NWC) Technical Business Practices (TBPs). It also provides recommendations on the application of Agile methods to the development of weapon/weapon-related software.

  11. Fighter agility metrics, research, and test

    NASA Technical Reports Server (NTRS)

    Liefer, Randall K.; Valasek, John; Eggold, David P.

    1990-01-01

    Proposed new metrics to assess fighter aircraft agility are collected and analyzed. A framework for classification of these new agility metrics is developed and applied. A completed set of transient agility metrics is evaluated with a high fidelity, nonlinear F-18 simulation provided by the NASA Dryden Flight Research Center. Test techniques and data reduction methods are proposed. A method of providing cuing information to the pilot during flight test is discussed. The sensitivity of longitudinal and lateral agility metrics to deviations from the pilot cues is studied in detail. The metrics are shown to be largely insensitive to reasonable deviations from the nominal test pilot commands. Instrumentation required to quantify agility via flight test is also considered. With one exception, each of the proposed new metrics may be measured with instrumentation currently available. Simulation documentation and user instructions are provided in an appendix.

  12. Agile Development Processes: Delivering a Successful Data Management Platform Now and in the Future

    NASA Astrophysics Data System (ADS)

    Deaubl, E.; Lowry, S.

    2007-10-01

    Developing a flexible, extensible architecture for scientific data archival and management is a monumental task under older, big design, up-front methodologies. We will describe how we are using agile development techniques in our service oriented architecture (SOA)-based platform to integrate astronomer and operator input into the development process, deliver functional software earlier, and ensure that the software is maintainable and extensible in the future.

  13. Lean Mission Operations Systems Design - Using Agile and Lean Development Principles for Mission Operations Design and Development

    NASA Technical Reports Server (NTRS)

    Trimble, Jay Phillip

    2014-01-01

    The Resource Prospector Mission seeks to rove the lunar surface with an in-situ resource utilization payload in search of volatiles at a polar region. The mission operations system (MOS) will need to perform the short-duration mission while taking advantage of the near real time control that the short one-way light time to the Moon provides. To maximize our use of limited resources for the design and development of the MOS we are utilizing agile and lean methods derived from our previous experience with applying these methods to software. By using methods such as "say it then sim it" we will spend less time in meetings and more time focused on the one outcome that counts - the effective utilization of our assets on the Moon to meet mission objectives.

  14. Collaboration, Communication and Co-ordination in Agile Software Development Practice

    NASA Astrophysics Data System (ADS)

    Robinson, Hugh; Sharp, Helen

    This chapter analyses the results of a series of observational studies of agile software developmentagile software development teams, identifying commonalities in collaboration, co-ordination and communication activities. Pairing and customer collaborationcustomer collaboration are focussed on to illustrate the nature of collaboration and communication, as are two simple physical artefacts that emerged through analysis as being an information-rich focal point for the co-ordination of collaboration and communication activities. The analysis shows that pairingpairing has common characteristics across all teams, while customer collaboration differs between the teams depending on the application and organisational context of development.

  15. Insights into Global Health Practice from the Agile Software Development Movement

    PubMed Central

    Flood, David; Chary, Anita; Austad, Kirsten; Diaz, Anne Kraemer; García, Pablo; Martinez, Boris; Canú, Waleska López; Rohloff, Peter

    2016-01-01

    Global health practitioners may feel frustration that current models of global health research, delivery, and implementation are overly focused on specific interventions, slow to provide health services in the field, and relatively ill-equipped to adapt to local contexts. Adapting design principles from the agile software development movement, we propose an analogous approach to designing global health programs that emphasizes tight integration between research and implementation, early involvement of ground-level health workers and program beneficiaries, and rapid cycles of iterative program improvement. Using examples from our own fieldwork, we illustrate the potential of ‘agile global health’ and reflect on the limitations, trade-offs, and implications of this approach. PMID:27134081

  16. Accelerating Software Development through Agile Practices--A Case Study of a Small-Scale, Time-Intensive Web Development Project at a College-Level IT Competition

    ERIC Educational Resources Information Center

    Zhang, Xuesong; Dorn, Bradley

    2012-01-01

    Agile development has received increasing interest both in industry and academia due to its benefits in developing software quickly, meeting customer needs, and keeping pace with the rapidly changing requirements. However, agile practices and scrum in particular have been mainly tested in mid- to large-size projects. In this paper, we present…

  17. Agile Project Management for e-Learning Developments

    ERIC Educational Resources Information Center

    Doherty, Iain

    2010-01-01

    We outline the project management tactics that we developed in praxis in order to manage elearning projects and show how our tactics were enhanced through implementing project management techniques from a formal project management methodology. Two key factors have contributed to our project management success. The first is maintaining a clear…

  18. An agile implementation of SCRUM

    NASA Astrophysics Data System (ADS)

    Gannon, Michele

    Is Agile a way to cut corners? To some, the use of an Agile Software Development Methodology has a negative connotation - “ Oh, you're just not producing any documentation” . So can a team with no experience in Agile successfully implement and use SCRUM?

  19. A Review of Agile and Lean Manufacturing as Issues in Selected International and National Research and Development Programs and Roadmaps

    ERIC Educational Resources Information Center

    Castro, Helio; Putnik, Goran D.; Shah, Vaibhav

    2012-01-01

    Purpose: The aim of this paper is to analyze international and national research and development (R&D) programs and roadmaps for the manufacturing sector, presenting how agile and lean manufacturing models are addressed in these programs. Design/methodology/approach: In this review, several manufacturing research and development programs and…

  20. Development of perceived competence, tactical skills, motivation, technical skills, and speed and agility in young soccer players.

    PubMed

    Forsman, Hannele; Gråstén, Arto; Blomqvist, Minna; Davids, Keith; Liukkonen, Jarmo; Konttinen, Niilo

    2016-07-01

    The objective of this 1-year, longitudinal study was to examine the development of perceived competence, tactical skills, motivation, technical skills, and speed and agility characteristics of young Finnish soccer players. We also examined associations between latent growth models of perceived competence and other recorded variables. Participants were 288 competitive male soccer players ranging from 12 to 14 years (12.7 ± 0.6) from 16 soccer clubs. Players completed the self-assessments of perceived competence, tactical skills, and motivation, and participated in technical, and speed and agility tests. Results of this study showed that players' levels of perceived competence, tactical skills, motivation, technical skills, and speed and agility characteristics remained relatively high and stable across the period of 1 year. Positive relationships were found between these levels and changes in perceived competence and motivation, and levels of perceived competence and speed and agility characteristics. Together these results illustrate the multi-dimensional nature of talent development processes in soccer. Moreover, it seems crucial in coaching to support the development of perceived competence and motivation in young soccer players and that it might be even more important in later maturing players. PMID:26708723

  1. Tools for Supporting Distributed Agile Project Planning

    NASA Astrophysics Data System (ADS)

    Wang, Xin; Maurer, Frank; Morgan, Robert; Oliveira, Josyleuda

    Agile project planning plays an important part in agile software development. In distributed settings, project planning is severely impacted by the lack of face-to-face communication and the inability to share paper index cards amongst all meeting participants. To address these issues, several distributed agile planning tools were developed. The tools vary in features, functions and running platforms. In this chapter, we first summarize the requirements for distributed agile planning. Then we give an overview on existing agile planning tools. We also evaluate existing tools based on tool requirements. Finally, we present some practical advices for both designers and users of distributed agile planning tools.

  2. Effects of speed, agility, quickness training method on power performance in elite soccer players.

    PubMed

    Jovanovic, Mario; Sporis, Goran; Omrcen, Darija; Fiorentini, Fredi

    2011-05-01

    The purpose of this study was to evaluate the effects of the speed, agility, quickness (SAQ) training method on power performance in soccer players. Soccer players were assigned randomly to 2 groups: experimental group (EG; n = 50) and control group (n = 50). Power performance was assessed by a test of quickness--the 5-m sprint, a test of acceleration--the 10-m sprint, tests of maximal speed--the 20- and the 30-m sprint along with Bosco jump tests--squat jump, countermovement jump (CMJ), maximal CMJ, and continuous jumps performed with legs extended. The initial testing procedure took place at the beginning of the in-season period. The 8-week specific SAQ training program was implemented after which final testing took place. The results of the 2-way analysis of variance indicated that the EG improved significantly (p < 0.05) in 5-m (1.43 vs. 1.39 seconds) and in 10-m (2.15 vs. 2.07 seconds) sprints, and they also improved their jumping performance in countermovement (44.04 vs. 4.48 cm) and continuous jumps (41.08 vs. 41.39 cm) performed with legs extended (p < 0.05). The SAQ training program appears to be an effective way of improving some segments of power performance in young soccer players during the in-season period. Soccer coaches could use this information in the process of planning in-season training. Without proper planning of the SAQ training, soccer players will most likely be confronted with decrease in power performance during in-season period. PMID:21522073

  3. Fighter agility metrics. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Liefer, Randall K.

    1990-01-01

    Fighter flying qualities and combat capabilities are currently measured and compared in terms relating to vehicle energy, angular rates and sustained acceleration. Criteria based on these measurable quantities have evolved over the past several decades and are routinely used to design aircraft structures, aerodynamics, propulsion and control systems. While these criteria, or metrics, have the advantage of being well understood, easily verified and repeatable during test, they tend to measure the steady state capability of the aircraft and not its ability to transition quickly from one state to another. Proposed new metrics to assess fighter aircraft agility are collected and analyzed. A framework for classification of these new agility metrics is developed and applied. A complete set of transient agility metrics is evaluated with a high fidelity, nonlinear F-18 simulation. Test techniques and data reduction methods are proposed. A method of providing cuing information to the pilot during flight test is discussed. The sensitivity of longitudinal and lateral agility metrics to deviations from the pilot cues is studied in detail. The metrics are shown to be largely insensitive to reasonable deviations from the nominal test pilot commands. Instrumentation required to quantify agility via flight test is also considered. With one exception, each of the proposed new metrics may be measured with instrumentation currently available.

  4. The NERV Methodology: Non-Functional Requirements Elicitation, Reasoning and Validation in Agile Processes

    ERIC Educational Resources Information Center

    Domah, Darshan

    2013-01-01

    Agile software development has become very popular around the world in recent years, with methods such as Scrum and Extreme Programming (XP). Literature suggests that functionality is the primary focus in Agile processes while non-functional requirements (NFR) are either ignored or ill-defined. However, for software to be of good quality both…

  5. Modeling and Developing the Information System for the SuperAGILE Experiment

    NASA Astrophysics Data System (ADS)

    Lazzarotto, F.; Costa, E.; del Monte, E.; Feroci, M.

    2004-07-01

    We will present some formal description of the SuperAGILE (SA) detection system data, the relationships among them and the operations applied on data, with the aid of instruments such as Entity-Relationship (E-R) and UML diagrams. We just realized functions of reception, pre-processing, archiving and analysis on SA data making use of Object Oriented and SQL open source software instruments.

  6. A Control Law Design Method Facilitating Control Power, Robustness, Agility, and Flying Qualities Tradeoffs: CRAFT

    NASA Technical Reports Server (NTRS)

    Murphy, Patrick C.; Davidson, John B.

    1998-01-01

    A multi-input, multi-output control law design methodology, named "CRAFT", is presented. CRAFT stands for the design objectives addressed, namely, Control power, Robustness, Agility, and Flying Qualities Tradeoffs. The methodology makes use of control law design metrics from each of the four design objective areas. It combines eigenspace assignment, which allows for direct specification of eigenvalues and eigenvectors, with a graphical approach for representing the metrics that captures numerous design goals in one composite illustration. Sensitivity of the metrics to eigenspace choice is clearly displayed, enabling the designer to assess the cost of design tradeoffs. This approach enhances the designer's ability to make informed design tradeoffs and to reach effective final designs. An example of the CRAFT methodology applied to an advanced experimental fighter and discussion of associated design issues are provided.

  7. Development and evaluation of an inverse solution technique for studying helicopter maneuverability and agility

    NASA Technical Reports Server (NTRS)

    Whalley, Matthew S.

    1991-01-01

    An inverse solution technique for determining the maximum maneuvering performance of a helicopter using smooth, pilotlike control inputs is presented. Also described is a pilot simulation experiment performed to investigate the accuracy of the solution resulting from this technique. The maneuverability and agility capability of the helicopter math model was varied by varying the pitch and roll damping, the maximum pitch and roll rate, and the maximum load-factor capability. Three maneuvers were investigated: a 180-deg turn, a longitudinal pop-up, and a lateral jink. The inverse solution technique yielded accurate predictions of pilot-in-the-loop maneuvering performance for two of the three maneuvers.

  8. Human factors in agile manufacturing

    SciTech Connect

    Forsythe, C.

    1995-03-01

    As industries position themselves for the competitive markets of today, and the increasingly competitive global markets of the 21st century, agility, or the ability to rapidly develop and produce new products, represents a common trend. Agility manifests itself in many different forms, with the agile manufacturing paradigm proposed by the Iacocca Institute offering a generally accepted, long-term vision. In its many forms, common elements of agility or agile manufacturing include: changes in business, engineering and production practices, seamless information flow from design through production, integration of computer and information technologies into all facets of the product development and production process, application of communications technologies to enable collaborative work between geographically dispersed product development team members and introduction of flexible automation of production processes. Industry has rarely experienced as dramatic an infusion of new technologies or as extensive a change in culture and work practices. Human factors will not only play a vital role in accomplishing the technical and social objectives of agile manufacturing. but has an opportunity to participate in shaping the evolution of industry paradigms for the 21st century.

  9. SU-E-T-610: Comparison of Treatment Times Between the MLCi and Agility Multileaf Collimators

    SciTech Connect

    Ramsey, C; Bowling, J

    2014-06-01

    Purpose: The Agility is a new 160-leaf MLC developed by Elekta for use in their Infinity and Versa HD linacs. As compared to the MLCi, the Agility increased the maximum leaf speed from 2 cm/s to 3.5 cm/s, and the maximum primary collimator speed from 1.5 cm/s to 9.0 cm/s. The purpose of this study was to determine if the Agility MLC resulted in improved plan quality and/or shorter treatment times. Methods: An Elekta Infinity that was originally equipped with a 80 leaf MLCi was upgraded to an 160 leaf Agility. Treatment plan quality was evaluated using the Pinnacle planning system with SmartArc. Optimization was performed once for the MLCi and once for the Agility beam models using the same optimization parameters and the same number of iterations. Patient treatment times were measured for all IMRT, VMAT, and SBRT patients treated on the Infinity with the MLCi and Agility MLCs. Treatment times were extracted from the EMR and measured from when the patient first walked into the treatment room until exiting the treatment room. Results: 11,380 delivery times were measured for patients treated with the MLCi, and 1,827 measurements have been made for the Agility MLC. The average treatment times were 19.1 minutes for the MLCi and 20.8 minutes for the Agility. Using a t-test analysis, there was no difference between the two groups (t = 0.22). The dose differences between patients planned with the MLCi and the Agility MLC were minimal. For example, the dose difference for the PTV, GTV, and cord for a head and neck patient planned using Pinnacle were effectively equivalent. However, the dose to the parotid glands was slightly worse with the Agility MLC. Conclusion: There was no statistical difference in treatment time, or any significant dosimetric difference between the Agility MLC and the MLCi.

  10. AGILE Data Center and AGILE science highlights

    NASA Astrophysics Data System (ADS)

    Pittori, C.

    2013-06-01

    AGILE is a scientific mission of the Italian Space Agency (ASI) with INFN, INAF e CIFS participation, devoted to gamma-ray astrophysics. The satellite is in orbit since April 23rd, 2007. Gamma-ray astrophysics above 100 MeV is an exciting field of astronomical sciences that has received a strong impulse in recent years. Despite the small size and budget, AGILE produced several important scientific results, among which the unexpected discovery of strong and rapid gamma-ray flares from the Crab Nebula. This discovery won to the AGILE PI and the AGILE Team the prestigious Bruno Rossi Prize for 2012, an international recognition in the field of high energy astrophysics. We present here the AGILE data center main activities, and we give an overview of the AGILE scientific highlights after 5 years of operations.

  11. CT-assisted agile manufacturing

    NASA Astrophysics Data System (ADS)

    Stanley, James H.; Yancey, Robert N.

    1996-11-01

    The next century will witness at least two great revolutions in the way goods are produced. First, workers will use the medium of virtual reality in all aspects of marketing, research, development, prototyping, manufacturing, sales and service. Second, market forces will drive manufacturing towards small-lot production and just-in-time delivery. Already, we can discern the merging of these megatrends into what some are calling agile manufacturing. Under this new paradigm, parts and processes will be designed and engineered within the mind of a computer, tooled and manufactured by the offspring of today's rapid prototyping equipment, and evaluated for performance and reliability by advanced nondestructive evaluation (NDE) techniques and sophisticated computational models. Computed tomography (CT) is the premier example of an NDE method suitable for future agile manufacturing activities. It is the only modality that provides convenient access to the full suite of engineering data that users will need to avail themselves of computer- aided design, computer-aided manufacturing, and computer- aided engineering capabilities, as well as newly emerging reverse engineering, rapid prototyping and solid freeform fabrication technologies. As such, CT is assured a central, utilitarian role in future industrial operations. An overview of this exciting future for industrial CT is presented.

  12. Requirement Changes and Project Success: The Moderating Effects of Agile Approaches in System Engineering Projects

    NASA Astrophysics Data System (ADS)

    Maierhofer, Sabine; Stelzmann, Ernst; Kohlbacher, Markus; Fellner, Björn

    This paper reports the findings of an empirical study on the influence agile development methods exert on the success of projects. The goal is to determine whether agile methods are able to mitigate negative effects requirement changes have on the performance of Systems Engineering projects, i.e. projects where systems consisting of hard- and software are developed. Agile methods have been proven to successfully support development projects in the field of traditional software engineering, but with an ever expending market of integrated systems manufacturers their usability for those complex projects has yet to be examined. This study focuses on 16 specific agile practices and their ability to improve the success of complex hard- and software projects.

  13. Agile manufacturing: The factory of the future

    NASA Technical Reports Server (NTRS)

    Loibl, Joseph M.; Bossieux, Terry A.

    1994-01-01

    The factory of the future will require an operating methodology which effectively utilizes all of the elements of product design, manufacturing and delivery. The process must respond rapidly to changes in product demand, product mix, design changes or changes in the raw materials. To achieve agility in a manufacturing operation, the design and development of the manufacturing processes must focus on customer satisfaction. Achieving greatest results requires that the manufacturing process be considered from product concept through sales. This provides the best opportunity to build a quality product for the customer at a reasonable rate. The primary elements of a manufacturing system include people, equipment, materials, methods and the environment. The most significant and most agile element in any process is the human resource. Only with a highly trained, knowledgeable work force can the proper methods be applied to efficiently process materials with machinery which is predictable, reliable and flexible. This paper discusses the affect of each element on the development of agile manufacturing systems.

  14. Frequency agile relativistic magnetrons

    SciTech Connect

    Levine, J.S.; Harteneck, B.D.; Price, H.D.

    1995-11-01

    The authors are developing a family of frequency agile relativistic magnetrons to continuously cover the bands from 1 to 3 GHz. They have achieved tuning ranges of > 33%. The magnetrons have been operated repetitively in burst mode at rates up to 100 pps for 10 sec. Power is extracted from two resonators, and is in the range of 400--600 MW, fairly flat across the tuning bandwidth. They are using a network of phase shifters and 3-dB hybrids to combine the power into a single arm and to provide a continuously adjustable attenuator.

  15. Current State of Agile User-Centered Design: A Survey

    NASA Astrophysics Data System (ADS)

    Hussain, Zahid; Slany, Wolfgang; Holzinger, Andreas

    Agile software development methods are quite popular nowadays and are being adopted at an increasing rate in the industry every year. However, these methods are still lacking usability awareness in their development lifecycle, and the integration of usability/User-Centered Design (UCD) into agile methods is not adequately addressed. This paper presents the preliminary results of a recently conducted online survey regarding the current state of the integration of agile methods and usability/UCD. A world wide response of 92 practitioners was received. The results show that the majority of practitioners perceive that the integration of agile methods with usability/UCD has added value to their adopted processes and to their teams; has resulted in the improvement of usability and quality of the product developed; and has increased the satisfaction of the end-users of the product developed. The top most used HCI techniques are low-fidelity prototyping, conceptual designs, observational studies of users, usability expert evaluations, field studies, personas, rapid iterative testing, and laboratory usability testing.

  16. Opening up the Agile Innovation Process

    NASA Astrophysics Data System (ADS)

    Conboy, Kieran; Donnellan, Brian; Morgan, Lorraine; Wang, Xiaofeng

    The objective of this panel is to discuss how firms can operate both an open and agile innovation process. In an era of unprecedented changes, companies need to be open and agile in order to adapt rapidly and maximize their innovation processes. Proponents of agile methods claim that one of the main distinctions between agile methods and their traditional bureaucratic counterparts is their drive toward creativity and innovation. However, agile methods are rarely adopted in their textbook, "vanilla" format, and are usually adopted in part or are tailored or modified to suit the organization. While we are aware that this happens, there is still limited understanding of what is actually happening in practice. Using innovation adoption theory, this panel will discuss the issues and challenges surrounding the successful adoption of agile practices. In addition, this panel will report on the obstacles and benefits reported by over 20 industrial partners engaged in a pan-European research project into agile practices between 2006 and 2009.

  17. Development and testing of a frequency-agile optical parametric oscillator system for differential absorption lidar

    NASA Astrophysics Data System (ADS)

    Weibring, P.; Smith, J. N.; Edner, H.; Svanberg, S.

    2003-10-01

    An all-solid-state fast-tuning lidar transmitter for range- and temporally resolved atmospheric gas concentration measurements has been developed and thoroughly tested. The instrument is based on a commercial optical parametric oscillator (OPO) laser system, which has been redesigned with piezoelectric transducers mounted on the wavelength-tuning mirror and on the crystal angle tuning element in the OPO. Piezoelectric transducers similarly control a frequency-mixing stage and doubling stage, which have been incorporated to extend system capabilities to the mid-IR and UV regions. The construction allows the system to be tuned to any wavelength, in any order, in the range of the piezoelectric transducers on a shot-to-shot basis. This extends the measurement capabilities far beyond the two-wavelength differential absorption lidar method and enables simultaneous measurements of several gases. The system performance in terms of wavelength, linewidth, and power stability is monitored in real time by an étalon-based wave meter and gas cells. The tests showed that the system was able to produce radiation in the 220-4300-nm-wavelength region, with an average linewidth better than 0.2 cm-1 and a shot-to-shot tunability up to 160 cm-1 within 20 ms. The utility of real-time linewidth and wavelength measurements is demonstrated by the ability to identify occasional poor quality laser shots and disregard these measurements. Also, absorption cell measurements of methane and mercury demonstrate the performance in obtaining stable wavelength and linewidth during rapid scans in the mid-IR and UV regions.

  18. Agility enabled by the SEMATECH CIM framework

    NASA Astrophysics Data System (ADS)

    Hawker, Scott; Waskiewicz, Fred

    1997-01-01

    The survivor in today's market environment is agile: able to survive and thrive in a market place marked by rapid, continuous change. For manufacturers, this includes an ability to rapidly develop, deploy and reconfigure manufacturing information and control systems. The SEMATECH CIM framework defines an application integration architecture and standard application components that enable agile manufacturing information and control systems. Further, the CIM framework and its evolution process foster virtual organizations of suppliers and manufacturers, combining their products and capabilities into an agile manufacturing information and control system.

  19. Customer Communication Challenges and Solutions in Globally Distributed Agile Software Development

    NASA Astrophysics Data System (ADS)

    Pikkarainen, Minna; Korkala, Mikko

    Working in the globally distributed market is one of the key trends among the software organizations all over the world. [1-5]. Several factors have contributed to the growth of distributed software development; time-zone independent ”follow the sun” development, access to well-educated labour, maturation of the technical infrastructure and reduced costs are some of the most commonly cited benefits of distributed development [3, 6-8]. Furthermore, customers are often located in different countries because of the companies’ internationalization purposes or good market opportunities.

  20. Design, implementation and validation of a novel open framework for agile development of mobile health applications

    PubMed Central

    2015-01-01

    The delivery of healthcare services has experienced tremendous changes during the last years. Mobile health or mHealth is a key engine of advance in the forefront of this revolution. Although there exists a growing development of mobile health applications, there is a lack of tools specifically devised for their implementation. This work presents mHealthDroid, an open source Android implementation of a mHealth Framework designed to facilitate the rapid and easy development of mHealth and biomedical apps. The framework is particularly planned to leverage the potential of mobile devices such as smartphones or tablets, wearable sensors and portable biomedical systems. These devices are increasingly used for the monitoring and delivery of personal health care and wellbeing. The framework implements several functionalities to support resource and communication abstraction, biomedical data acquisition, health knowledge extraction, persistent data storage, adaptive visualization, system management and value-added services such as intelligent alerts, recommendations and guidelines. An exemplary application is also presented along this work to demonstrate the potential of mHealthDroid. This app is used to investigate on the analysis of human behavior, which is considered to be one of the most prominent areas in mHealth. An accurate activity recognition model is developed and successfully validated in both offline and online conditions. PMID:26329639

  1. Design, implementation and validation of a novel open framework for agile development of mobile health applications.

    PubMed

    Banos, Oresti; Villalonga, Claudia; Garcia, Rafael; Saez, Alejandro; Damas, Miguel; Holgado-Terriza, Juan A; Lee, Sungyong; Pomares, Hector; Rojas, Ignacio

    2015-01-01

    The delivery of healthcare services has experienced tremendous changes during the last years. Mobile health or mHealth is a key engine of advance in the forefront of this revolution. Although there exists a growing development of mobile health applications, there is a lack of tools specifically devised for their implementation. This work presents mHealthDroid, an open source Android implementation of a mHealth Framework designed to facilitate the rapid and easy development of mHealth and biomedical apps. The framework is particularly planned to leverage the potential of mobile devices such as smartphones or tablets, wearable sensors and portable biomedical systems. These devices are increasingly used for the monitoring and delivery of personal health care and wellbeing. The framework implements several functionalities to support resource and communication abstraction, biomedical data acquisition, health knowledge extraction, persistent data storage, adaptive visualization, system management and value-added services such as intelligent alerts, recommendations and guidelines. An exemplary application is also presented along this work to demonstrate the potential of mHealthDroid. This app is used to investigate on the analysis of human behavior, which is considered to be one of the most prominent areas in mHealth. An accurate activity recognition model is developed and successfully validated in both offline and online conditions. PMID:26329639

  2. Development of Robust, Light-weight, Agile Deformable Mirrors in Carbon Fiber

    NASA Astrophysics Data System (ADS)

    Hart, M.; Ammons, S. M.; Coughenour, B.; Richardson, L.,; Romeo, R.; Martin, R.

    2012-09-01

    Carbon fiber reinforced polymer (CFRP) has recently been developed to the point that surfaces of high optical quality can be routinely replicated. Building on this advance, we are developing a new generation of deformable mirrors (DMs) for adaptive optics application that extends long-standing expertise at the University of Arizona in large, optically powered DMs for astronomy. Our existing mirrors, up to 90 cm in diameter and with aspheric deformable facesheets, are deployed on a number of large astronomical telescopes. With actuator stroke of up to 50 microns and no hysteresis, they are delivering the best imaging ever seen from an astronomical AO system. Their Zerodur glass ceramic facesheets though are not well suited to non-astronomical applications. In this paper, we describe developmental work to replace the glass components of the DMs with CFRP, an attractive material for optics fabrication because of its high stiffness-to-weight ratio, strength, and very low coefficient of thermal expansion. Surface roughness arising from fiber print-through in the CFRP facesheets is low, < 3 nm PTV across a range of temperature, and the optical figure after correction of static terms by the DM actuators is on the order of 20 nm rms. After initial investment in an optical quality mandrel, replication costs of identical units in CFRP are very low, making the technology ideal for rapid mass production.

  3. Use of piloted simulation for high-angle-of-attack agility research and design criteria development

    NASA Technical Reports Server (NTRS)

    Ogburn, Marilyn E.; Foster, John V.; Hoffler, Keith D.

    1991-01-01

    The application of piloted simulations in the development of advanced fighter aircraft is reviewed in the context of the NASA High-Angle-of-Attack Technology Program (HATP). The HATP combines wind-tunnel experiments, computational aerodynamics, piloted simulations, and flight tests on a modified F-18 testbed aircraft and utilizes the experience and facilities of several NASA centers. Consideration is given to the role of simulation in the overall research process, simulation capabilities and software requirements, simulation flexibility and fidelity, evaluation maneuvers, the role of simulator pilots in evaluations, the analysis of simulation results, flight validation of maneuvers and rating approaches, and the use of simulations to define design criteria. Extensive diagrams, graphs, and flow charts are included.

  4. Towards a Better Understanding of CMMI and Agile Integration - Multiple Case Study of Four Companies

    NASA Astrophysics Data System (ADS)

    Pikkarainen, Minna

    The amount of software is increasing in the different domains in Europe. This provides the industries in smaller countries good opportunities to work in the international markets. Success in the global markets however demands the rapid production of high quality, error free software. Both CMMI and agile methods seem to provide a ready solution for quality and lead time improvements. There is not, however, much empirical evidence available either about 1) how the integration of these two aspects can be done in practice or 2) what it actually demands from assessors and software process improvement groups. The goal of this paper is to increase the understanding of CMMI and agile integration, in particular, focusing on the research question: how to use ‘lightweight’ style of CMMI assessments in agile contexts. This is done via four case studies in which assessments were conducted using the goals of CMMI integrated project management and collaboration and coordination with relevant stakeholder process areas and practices from XP and Scrum. The study shows that the use of agile practices may support the fulfilment of the goals of CMMI process areas but there are still many challenges for the agile teams to be solved within the continuous improvement programs. It also identifies practical advices to the assessors and improvement groups to take into consideration when conducting assessment in the context of agile software development.

  5. Preparing your Offshore Organization for Agility: Experiences in India

    NASA Astrophysics Data System (ADS)

    Srinivasan, Jayakanth

    Two strategies that have significantly changed the way we conventionally think about managing software development and sustainment are the family of development approaches collectively referred to as agile methods, and the distribution of development efforts on a global scale. When you combine the two strategies, organizations have to address not only the technical challenges that arise from introducing new ways of working, but more importantly have to manage the 'soft' factors that if ignored lead to hard challenges. Using two case studies of distributed agile software development in India we illustrate the areas that organizations need to be aware of when transitioning work to India. The key issues that we emphasize are the need to recruit and retain personnel; the importance of teaching, mentoring and coaching; the need to manage customer expectations; the criticality of well-articulated senior leadership vision and commitment; and the reality of operating in a heterogeneous process environment.

  6. An Agile Constructionist Mentoring Methodology for Software Projects in the High School

    ERIC Educational Resources Information Center

    Meerbaum-Salant, Orni; Hazzan, Orit

    2010-01-01

    This article describes the construction process and evaluation of the Agile Constructionist Mentoring Methodology (ACMM), a mentoring method for guiding software development projects in the high school. The need for such a methodology has arisen due to the complexity of mentoring software project development in the high school. We introduce the…

  7. Agile manufacturing in Intelligence, Surveillance and Reconnaissance (ISR)

    NASA Astrophysics Data System (ADS)

    DiPadua, Mark; Dalton, George

    2016-05-01

    The objective of the Agile Manufacturing for Intelligence, Surveillance, and Reconnaissance (AMISR) effort is to research, develop, design and build a prototype multi-intelligence (multi-INT), reconfigurable pod demonstrating benefits of agile manufacturing and a modular open systems approach (MOSA) to make podded intelligence, surveillance, and reconnaissance (ISR) capability more affordable and operationally flexible.

  8. Analysis and optimization of preliminary aircraft configurations in relationship to emerging agility metrics

    NASA Technical Reports Server (NTRS)

    Sandlin, Doral R.; Bauer, Brent Alan

    1993-01-01

    This paper discusses the development of a FORTRAN computer code to perform agility analysis on aircraft configurations. This code is to be part of the NASA-Ames ACSYNT (AirCraft SYNThesis) design code. This paper begins with a discussion of contemporary agility research in the aircraft industry and a survey of a few agility metrics. The methodology, techniques and models developed for the code are then presented. Finally, example trade studies using the agility module along with ACSYNT are illustrated. These trade studies were conducted using a Northrop F-20 Tigershark aircraft model. The studies show that the agility module is effective in analyzing the influence of common parameters such as thrust-to-weight ratio and wing loading on agility criteria. The module can compare the agility potential between different configurations. In addition one study illustrates the module's ability to optimize a configuration's agility performance.

  9. Enterprise Technologies Deployment for Agile Manufacturing

    SciTech Connect

    Neal, R.E.

    1992-11-01

    This report is intended for high-level technical planners who are responsible for planning future developments for their company or Department of Energy/Defense Programs (DOE/DP) facilities. On one hand, the information may be too detailed or contain too much manufacturing technology jargon for a high-level, nontechnical executive, while at the same time an expert in any of the four infrastructure fields (Product Definition/Order Entry, Planning and Scheduling, Shop Floor Management, and Intelligent Manufacturing Systems) will know more than is conveyed here. The purpose is to describe a vision of technology deployment for an agile manufacturing enterprise. According to the 21st Century Manufacturing Enterprise Strategy, the root philosophy of agile manufacturing is that ``competitive advantage in the new systems will belong to agile manufacturing enterprises, capable of responding rapidly to demand for high-quality, highly customized products.`` Such agility will be based on flexible technologies, skilled workers, and flexible management structures which collectively will foster cooperative initiatives in and among companies. The remainder of this report is dedicated to sharpening our vision and to establishing a framework for defining specific project or pre-competitive project goals which will demonstrate agility through technology deployment.

  10. Enterprise Technologies Deployment for Agile Manufacturing

    SciTech Connect

    Neal, R.E.

    1992-11-01

    This report is intended for high-level technical planners who are responsible for planning future developments for their company or Department of Energy/Defense Programs (DOE/DP) facilities. On one hand, the information may be too detailed or contain too much manufacturing technology jargon for a high-level, nontechnical executive, while at the same time an expert in any of the four infrastructure fields (Product Definition/Order Entry, Planning and Scheduling, Shop Floor Management, and Intelligent Manufacturing Systems) will know more than is conveyed here. The purpose is to describe a vision of technology deployment for an agile manufacturing enterprise. According to the 21st Century Manufacturing Enterprise Strategy, the root philosophy of agile manufacturing is that competitive advantage in the new systems will belong to agile manufacturing enterprises, capable of responding rapidly to demand for high-quality, highly customized products.'' Such agility will be based on flexible technologies, skilled workers, and flexible management structures which collectively will foster cooperative initiatives in and among companies. The remainder of this report is dedicated to sharpening our vision and to establishing a framework for defining specific project or pre-competitive project goals which will demonstrate agility through technology deployment.

  11. Agile parallel bioinformatics workflow management using Pwrake

    PubMed Central

    2011-01-01

    Background In bioinformatics projects, scientific workflow systems are widely used to manage computational procedures. Full-featured workflow systems have been proposed to fulfil the demand for workflow management. However, such systems tend to be over-weighted for actual bioinformatics practices. We realize that quick deployment of cutting-edge software implementing advanced algorithms and data formats, and continuous adaptation to changes in computational resources and the environment are often prioritized in scientific workflow management. These features have a greater affinity with the agile software development method through iterative development phases after trial and error. Here, we show the application of a scientific workflow system Pwrake to bioinformatics workflows. Pwrake is a parallel workflow extension of Ruby's standard build tool Rake, the flexibility of which has been demonstrated in the astronomy domain. Therefore, we hypothesize that Pwrake also has advantages in actual bioinformatics workflows. Findings We implemented the Pwrake workflows to process next generation sequencing data using the Genomic Analysis Toolkit (GATK) and Dindel. GATK and Dindel workflows are typical examples of sequential and parallel workflows, respectively. We found that in practice, actual scientific workflow development iterates over two phases, the workflow definition phase and the parameter adjustment phase. We introduced separate workflow definitions to help focus on each of the two developmental phases, as well as helper methods to simplify the descriptions. This approach increased iterative development efficiency. Moreover, we implemented combined workflows to demonstrate modularity of the GATK and Dindel workflows. Conclusions Pwrake enables agile management of scientific workflows in the bioinformatics domain. The internal domain specific language design built on Ruby gives the flexibility of rakefiles for writing scientific workflows. Furthermore, readability

  12. FODEM: A Multi-Threaded Research and Development Method for Educational Technology

    ERIC Educational Resources Information Center

    Suhonen, Jarkko; de Villiers, M. Ruth; Sutinen, Erkki

    2012-01-01

    Formative development method (FODEM) is a multithreaded design approach that was originated to support the design and development of various types of educational technology innovations, such as learning tools, and online study programmes. The threaded and agile structure of the approach provides flexibility to the design process. Intensive…

  13. An investigation of fighter aircraft agility

    NASA Technical Reports Server (NTRS)

    Valasek, John; Downing, David R.

    1993-01-01

    This report attempts to unify in a single document the results of a series of studies on fighter aircraft agility funded by the NASA Ames Research Center, Dryden Flight Research Facility and conducted at the University of Kansas Flight Research Laboratory during the period January 1989 through December 1993. New metrics proposed by pilots and the research community to assess fighter aircraft agility are collected and analyzed. The report develops a framework for understanding the context into which the various proposed fighter agility metrics fit in terms of application and testing. Since new metrics continue to be proposed, this report does not claim to contain every proposed fighter agility metric. Flight test procedures, test constraints, and related criteria are developed. Instrumentation required to quantify agility via flight test is considered, as is the sensitivity of the candidate metrics to deviations from nominal pilot command inputs, which is studied in detail. Instead of supplying specific, detailed conclusions about the relevance or utility of one candidate metric versus another, the authors have attempted to provide sufficient data and analyses for readers to formulate their own conclusions. Readers are therefore ultimately responsible for judging exactly which metrics are 'best' for their particular needs. Additionally, it is not the intent of the authors to suggest combat tactics or other actual operational uses of the results and data in this report. This has been left up to the user community. Twenty of the candidate agility metrics were selected for evaluation with high fidelity, nonlinear, non real-time flight simulation computer programs of the F-5A Freedom Fighter, F-16A Fighting Falcon, F-18A Hornet, and X-29A. The information and data presented on the 20 candidate metrics which were evaluated will assist interested readers in conducting their own extensive investigations. The report provides a definition and analysis of each metric; details

  14. Perspectives on Agile Coaching

    NASA Astrophysics Data System (ADS)

    Fraser, Steven; Lundh, Erik; Davies, Rachel; Eckstein, Jutta; Larsen, Diana; Vilkki, Kati

    There are many perspectives to agile coaching including: growing coaching expertise, selecting the appropriate coach for your context; and eva luating value. A coach is often an itinerant who may observe, mentor, negotiate, influence, lead, and/or architect everything from team organization to system architecture. With roots in diverse fields ranging from technology to sociology coaches have differing motivations and experience bases. This panel will bring together coaches to debate and discuss various perspectives on agile coaching. Some of the questions to be addressed will include: What are the skills required for effective coaching? What should be the expectations for teams or individu als being coached? Should coaches be: a corporate resource (internal team of consultants working with multiple internal teams); an integral part of a specific team; or external contractors? How should coaches exercise influence and au thority? How should management assess the value of a coaching engagement? Do you have what it takes to be a coach? - This panel will bring together sea soned agile coaches to offer their experience and advice on how to be the best you can be!

  15. Agile Walking Robot

    NASA Technical Reports Server (NTRS)

    Larimer, Stanley J.; Lisec, Thomas R.; Spiessbach, Andrew J.; Waldron, Kenneth J.

    1990-01-01

    Proposed agile walking robot operates over rocky, sandy, and sloping terrain. Offers stability and climbing ability superior to other conceptual mobile robots. Equipped with six articulated legs like those of insect, continually feels ground under leg before applying weight to it. If leg sensed unexpected object or failed to make contact with ground at expected point, seeks alternative position within radius of 20 cm. Failing that, robot halts, examines area around foot in detail with laser ranging imager, and replans entire cycle of steps for all legs before proceeding.

  16. Agile Infrastructure Monitoring

    NASA Astrophysics Data System (ADS)

    Andrade, P.; Ascenso, J.; Fedorko, I.; Fiorini, B.; Paladin, M.; Pigueiras, L.; Santos, M.

    2014-06-01

    At the present time, data centres are facing a massive rise in virtualisation and cloud computing. The Agile Infrastructure (AI) project is working to deliver new solutions to ease the management of CERN data centres. Part of the solution consists in a new "shared monitoring architecture" which collects and manages monitoring data from all data centre resources. In this article, we present the building blocks of this new monitoring architecture, the different open source technologies selected for each architecture layer, and how we are building a community around this common effort.

  17. Frequency agile optical parametric oscillator

    DOEpatents

    Velsko, Stephan P.

    1998-01-01

    The frequency agile OPO device converts a fixed wavelength pump laser beam to arbitrary wavelengths within a specified range with pulse to pulse agility, at a rate limited only by the repetition rate of the pump laser. Uses of this invention include Laser radar, LIDAR, active remote sensing of effluents/pollutants, environmental monitoring, antisensor lasers, and spectroscopy.

  18. Frequency agile optical parametric oscillator

    DOEpatents

    Velsko, S.P.

    1998-11-24

    The frequency agile OPO device converts a fixed wavelength pump laser beam to arbitrary wavelengths within a specified range with pulse to pulse agility, at a rate limited only by the repetition rate of the pump laser. Uses of this invention include Laser radar, LIDAR, active remote sensing of effluents/pollutants, environmental monitoring, antisensor lasers, and spectroscopy. 14 figs.

  19. Achieving agility through parameter space qualification

    SciTech Connect

    Diegert, K.V.; Easterling, R.G.; Ashby, M.R.; Benavides, G.L.; Forsythe, C.; Jones, R.E.; Longcope, D.B.; Parratt, S.W.

    1995-02-01

    The A-primed (Agile Product Realization of Innovative electro-Mechanical Devices) project is defining and proving processes for agile product realization for the Department of Energy complex. Like other agile production efforts reported in the literature, A-primed uses concurrent engineering and information automation technologies to enhance information transfer. A unique aspect of our approach to agility is the qualification during development of a family of related product designs and their production processes, rather than a single design and its attendant processes. Applying engineering principles and statistical design of experiments, economies of test and analytic effort are realized for the qualification of the device family as a whole. Thus the need is minimized for test and analysis to qualify future devices from this family, thereby further reducing the design-to-production cycle time. As a measure of the success of the A-primed approach, the first design took 24 days to produce, and operated correctly on the first attempt. A flow diagram for the qualification process is presented. Guidelines are given for implementation, based on the authors experiences as members of the A-primed qualification team.

  20. I'll Txt U if I Have a Problem: How the Société Canadienne du Cancer in Quebec Applied Behavior-Change Theory, Data Mining and Agile Software Development to Help Young Adults Quit Smoking

    PubMed Central

    van Mierlo, Trevor; Fournier, Rachel; Jean-Charles, Anathalie; Hovington, Jacinthe; Ethier, Isabelle; Selby, Peter

    2014-01-01

    Introduction For many organizations, limited budgets and phased funding restrict the development of digital health tools. This problem is often exacerbated by the ever-increasing sophistication of technology and costs related to programming and maintenance. Traditional development methods tend to be costly and inflexible and not client centered. The purpose of this study is to analyze the use of Agile software development and outcomes of a three-phase mHealth program designed to help young adult Quebecers quit smoking. Methods In Phase I, literature reviews, focus groups, interviews, and behavior change theory were used in the adaption and re-launch of an existing evidence-based mHealth platform. Based on analysis of user comments and utilization data from Phase I, the second phase expanded the service to allow participants to live text-chat with counselors. Phase II evaluation led to the third and current phase, in which algorithms were introduced to target pregnant smokers, substance users, students, full-time workers, those affected by mood disorders and chronic disease. Results Data collected throughout the three phases indicate that the incremental evolution of the intervention has led to increasing numbers of smokers being enrolled while making functional enhancements. In Phase I (240 days) 182 smokers registered with the service. 51% (n = 94) were male and 61.5% (n = 112) were between the ages of 18–24. In Phase II (300 days), 994 smokers registered with the service. 51% (n = 508) were male and 41% (n = 403) were between the ages of 18–24. At 174 days to date 873 smokers have registered in the third phase. 44% (n = 388) were male and 24% (n = 212) were between the ages of 18–24. Conclusions Emerging technologies in behavioral science show potential, but do not have defined best practices for application development. In phased-based projects with limited funding, Agile appears to be a viable approach to building and expanding

  1. Application of side-oblique image-motion blur correction to Kuaizhou-1 agile optical images.

    PubMed

    Sun, Tao; Long, Hui; Liu, Bao-Cheng; Li, Ying

    2016-03-21

    Given the recent development of agile optical satellites for rapid-response land observation, side-oblique image-motion (SOIM) detection and blur correction have become increasingly essential for improving the radiometric quality of side-oblique images. The Chinese small-scale agile mapping satellite Kuaizhou-1 (KZ-1) was developed by the Harbin Institute of Technology and launched for multiple emergency applications. Like other agile satellites, KZ-1 suffers from SOIM blur, particularly in captured images with large side-oblique angles. SOIM detection and blur correction are critical for improving the image radiometric accuracy. This study proposes a SOIM restoration method based on segmental point spread function detection. The segment region width is determined by satellite parameters such as speed, height, integration time, and side-oblique angle. The corresponding algorithms and a matrix form are proposed for SOIM blur correction. Radiometric objective evaluation indices are used to assess the restoration quality. Beijing regional images from KZ-1 are used as experimental data. The radiometric quality is found to increase greatly after SOIM correction. Thus, the proposed method effectively corrects image motion for KZ-1 agile optical satellites. PMID:27136855

  2. Agile rediscovering values: Similarities to continuous improvement strategies

    NASA Astrophysics Data System (ADS)

    Díaz de Mera, P.; Arenas, J. M.; González, C.

    2012-04-01

    Research in the late 80's on technological companies that develop products of high value innovation, with sufficient speed and flexibility to adapt quickly to changing market conditions, gave rise to the new set of methodologies known as Agile Management Approach. In the current changing economic scenario, we considered very interesting to study the similarities of these Agile Methodologies with other practices whose effectiveness has been amply demonstrated in both the West and Japan. Strategies such as Kaizen, Lean, World Class Manufacturing, Concurrent Engineering, etc, would be analyzed to check the values they have in common with the Agile Approach.

  3. Aircraft agility maneuvers

    NASA Technical Reports Server (NTRS)

    Cliff, Eugene M.; Thompson, Brian G.

    1992-01-01

    A new dynamic model for aircraft motions is presented. This model can be viewed as intermediate between a point-mass model, in which the body attitude angles are control-like, and a rigid-body model, in which the body-attitude angles evolve according to Newton's Laws. Specifically, consideration is given to the case of symmetric flight, and a model is constructed in which the body roll-rate and the body pitch-rate are the controls. In terms of this body-rate model a minimum-time heading change maneuver is formulated. When the bounds on the body-rates are large the results are similar to the point-mass model in that the model can very quickly change the applied forces and produce an acceleration to turn the vehicle. With finite bounds on these rates, the forces change in a smooth way. This leads to a measurable effect of agility.

  4. Agile manufacturing concept

    NASA Astrophysics Data System (ADS)

    Goldman, Steven L.

    1994-03-01

    The initial conceptualization of agile manufacturing was the result of a 1991 study -- chaired by Lehigh Professor Roger N. Nagel and California-based entrepreneur Rick Dove, President of Paradigm Shifts, International -- of what it would take for U.S. industry to regain global manufacturing competitiveness by the early twenty-first century. This industry-led study, reviewed by senior management at over 100 companies before its release, concluded that incremental improvement of the current system of manufacturing would not be enough to be competitive in today's global marketplace. Computer-based information and production technologies that were becoming available to industry opened up the possibility of an altogether new system of manufacturing, one that would be characterized by a distinctive integration of people and technologies; of management and labor; of customers, producers, suppliers, and society.

  5. Agile robotic edge finishing system research

    SciTech Connect

    Powell, M.A.

    1995-07-01

    This paper describes a new project undertaken by Sandia National Laboratories to develop an agile, automated, high-precision edge finishing system. The project has a two-year duration and was initiated in October, 1994. This project involves re-designing and adding additional capabilities to an existing finishing workcell at Sandia; and developing intelligent methods for automating process definition and for controlling finishing processes. The resulting system will serve as a prototype for systems that will be deployed into highly flexible automated production lines. The production systems will be used to produce a wide variety of products with limited production quantities and quick turnaround requirements. The prototype system is designed to allow programming, process definition, fixture re-configuration, and process verification to be performed off-line for new products. CAD/CAM (Computer Aided Design/Computer Aided Manufacturing) models of the part will be used to assist with the automated process development and process control tasks. To achieve Sandia`s performance goals, the system will be employ advanced path planning, burr prediction expert systems, automated process definition, statistical process models in a process database, and a two-level control scheme using hybrid position-force control and fuzzy logic control. In this paper, we discuss the progress and the planned system development under this project.

  6. Elements of an Art - Agile Coaching

    NASA Astrophysics Data System (ADS)

    Lundh, Erik

    This tutorial gives you a lead on becoming or redefining yourself as an Agile Coach. Introduction to elements and dimensions of state-of-the-art Agile Coaching. How to position the agile coach to be effective in a larger setting. Making the agile transition - from a single team to thousands of people. How to support multiple teams as a coach. How to build a coaches network in your company. Challenges when the agile coach is a consultant and the organization is large.

  7. Investigation into the impact of agility on conceptual fighter design

    NASA Technical Reports Server (NTRS)

    Engelbeck, R. M.

    1995-01-01

    The Agility Design Study was performed by the Boeing Defense and Space Group for the NASA Langley Research Center. The objective of the study was to assess the impact of agility requirements on new fighter configurations. Global trade issues investigated were the level of agility, the mission role of the aircraft (air-to-ground, multi-role, or air-to-air), and whether the customer is Air force, Navy, or joint service. Mission profiles and design objectives were supplied by NASA. An extensive technology assessment was conducted to establish the available technologies to industry for the aircraft. Conceptual level methodology is presented to assess the five NASA-supplied agility metrics. Twelve configurations were developed to address the global trade issues. Three-view drawings, inboard profiles, and performance estimates were made and are included in the report. A critical assessment and lessons learned from the study are also presented.

  8. The Telemetry Agile Manufacturing Effort

    SciTech Connect

    Brown, K.D.

    1995-01-01

    The Telemetry Agile Manufacturing Effort (TAME) is an agile enterprising demonstration sponsored by the US Department of Energy (DOE). The project experimented with new approaches to product realization and assessed their impacts on performance, cost, flow time, and agility. The purpose of the project was to design the electrical and mechanical features of an integrated telemetry processor, establish the manufacturing processes, and produce an initial production lot of two to six units. This paper outlines the major methodologies utilized by the TAME, describes the accomplishments that can be attributed to each methodology, and finally, examines the lessons learned and explores the opportunities for improvement associated with the overall effort. The areas for improvement are discussed relative to an ideal vision of the future for agile enterprises. By the end of the experiment, the TAME reduced production flow time by approximately 50% and life cycle cost by more than 30%. Product performance was improved compared with conventional DOE production approaches.

  9. Compact, Automated, Frequency-Agile Microspectrofluorimeter

    NASA Technical Reports Server (NTRS)

    Fernandez, Salvador M.; Guignon, Ernest F.

    1995-01-01

    Compact, reliable, rugged, automated cell-culture and frequency-agile microspectrofluorimetric apparatus developed to perform experiments involving photometric imaging observations of single live cells. In original application, apparatus operates mostly unattended aboard spacecraft; potential terrestrial applications include automated or semiautomated diagnosis of pathological tissues in clinical laboratories, biomedical instrumentation, monitoring of biological process streams, and portable instrumentation for testing biological conditions in various environments. Offers obvious advantages over present laboratory instrumentation.

  10. APID: Agile Protein Interaction DataAnalyzer.

    PubMed

    Prieto, Carlos; De Las Rivas, Javier

    2006-07-01

    Agile Protein Interaction DataAnalyzer (APID) is an interactive bioinformatics web tool developed to integrate and analyze in a unified and comparative platform main currently known information about protein-protein interactions demonstrated by specific small-scale or large-scale experimental methods. At present, the application includes information coming from five main source databases enclosing an unified sever to explore >35 000 different proteins and 111 000 different proven interactions. The web includes search tools to query and browse upon the data, allowing selection of the interaction pairs based in calculated parameters that weight and qualify the reliability of each given protein interaction. Such parameters are for the 'proteins': connectivity, cluster coefficient, Gene Ontology (GO) functional environment, GO environment enrichment; and for the 'interactions': number of methods, GO overlapping, iPfam domain-domain interaction. APID also includes a graphic interactive tool to visualize selected sub-networks and to navigate on them or along the whole interaction network. The application is available open access at http://bioinfow.dep.usal.es/apid/. PMID:16845013

  11. Agile automated vision

    NASA Astrophysics Data System (ADS)

    Fandrich, Juergen; Schmitt, Lorenz A.

    1994-11-01

    The microelectronic industry is a protagonist in driving automated vision to new paradigms. Today semiconductor manufacturers use vision systems quite frequently in their fabs in the front-end process. In fact, the process depends on reliable image processing systems. In the back-end process, where ICs are assembled and packaged, today vision systems are only partly used. But in the next years automated vision will become compulsory for the back-end process as well. Vision will be fully integrated into every IC package production machine to increase yields and reduce costs. Modem high-speed material processing requires dedicated and efficient concepts in image processing. But the integration of various equipment in a production plant leads to unifying handling of data flow and interfaces. Only agile vision systems can act with these contradictions: fast, reliable, adaptable, scalable and comprehensive. A powerful hardware platform is a unneglectable requirement for the use of advanced and reliable, but unfortunately computing intensive image processing algorithms. The massively parallel SIMD hardware product LANTERN/VME supplies a powerful platform for existing and new functionality. LANTERN/VME is used with a new optical sensor for IC package lead inspection. This is done in 3D, including horizontal and coplanarity inspection. The appropriate software is designed for lead inspection, alignment and control tasks in IC package production and handling equipment, like Trim&Form, Tape&Reel and Pick&Place machines.

  12. Final Report of the NASA Office of Safety and Mission Assurance Agile Benchmarking Team

    NASA Technical Reports Server (NTRS)

    Wetherholt, Martha

    2016-01-01

    To ensure that the NASA Safety and Mission Assurance (SMA) community remains in a position to perform reliable Software Assurance (SA) on NASAs critical software (SW) systems with the software industry rapidly transitioning from waterfall to Agile processes, Terry Wilcutt, Chief, Safety and Mission Assurance, Office of Safety and Mission Assurance (OSMA) established the Agile Benchmarking Team (ABT). The Team's tasks were: 1. Research background literature on current Agile processes, 2. Perform benchmark activities with other organizations that are involved in software Agile processes to determine best practices, 3. Collect information on Agile-developed systems to enable improvements to the current NASA standards and processes to enhance their ability to perform reliable software assurance on NASA Agile-developed systems, 4. Suggest additional guidance and recommendations for updates to those standards and processes, as needed. The ABT's findings and recommendations for software management, engineering and software assurance are addressed herein.

  13. Radiochemical method development

    SciTech Connect

    Erickson, M.D.; Aldstadt, J.H.; Alvarado, J.S.; Crain, J.S.; Orlandini, K.A.; Smith, L.L.

    1994-09-01

    The authors have developed methods for chemical characterization of the environment under a multitask project that focuses on improvement of radioanalytical methods with an emphasis on faster and cheaper routine methods. The authors have developed improved methods for separation of environmental levels of technetium-99, radium, and actinides from soil and water; separation of actinides from soil and water matrix interferences; and isolation of strontium. They are also developing methods for simultaneous detection of multiple isotopes (including nonradionuclides) by using a new instrumental technique, inductively coupled plasma-mass spectrometry (ICP-MS). The new ICP-MS methods have greater sensitivity and efficiency and could replace many radiometric techniques. They are using flow injection analysis to integrate and automate the separation methods with the ICP-MS methodology. The final product of all activities will be methods that are available (published in the U.S. Department of Energy`s analytical methods compendium) and acceptable for use in regulatory situations.

  14. Embedding Agile Practices within a Plan-Driven Hierarchical Project Life Cycle

    SciTech Connect

    Millard, W. David; Johnson, Daniel M.; Henderson, John M.; Lombardo, Nicholas J.; Bass, Robert B.; Smith, Jason E.

    2014-07-28

    Organizations use structured, plan-driven approaches to provide continuity, direction, and control to large, multi-year programs. Projects within these programs vary greatly in size, complexity, level of maturity, technical risk, and clarity of the development objectives. Organizations that perform exploratory research, evolutionary development, and other R&D activities can obtain the benefits of Agile practices without losing the benefits of their program’s overarching plan-driven structure. This paper describes application of Agile development methods on a large plan-driven sensor integration program. While the client employed plan-driven, requirements flow-down methodologies, tight project schedules and complex interfaces called for frequent end-to-end demonstrations to provide feedback during system development. The development process maintained the many benefits of plan-driven project execution with the rapid prototyping, integration, demonstration, and client feedback possible through Agile development methods. This paper also describes some of the tools and implementing mechanisms used to transition between and take advantage of each methodology, and presents lessons learned from the project management, system engineering, and developer’s perspectives.

  15. What Does an Agile Coach Do?

    NASA Astrophysics Data System (ADS)

    Davies, Rachel; Pullicino, James

    The surge in Agile adoption has created a demand for project managers rather than direct their teams. A sign of this trend is the ever-increasing number of people getting certified as scrum masters and agile leaders. Training courses that introduce agile practices are easy to find. But making the transition to coach is not as simple as understanding what agile practices are. Your challenge as an Agile Coach is to support your team in learning how to wield their new Agile tools in creating great software.

  16. Piloted simulator assessments of agility

    NASA Technical Reports Server (NTRS)

    Schneider, Edward T.

    1990-01-01

    NASA has utilized piloted simulators for nearly two decades to study high-angle-of-attack flying qualities, agility, and air-to-air combat. These studies have included assessments of an F-16XL aircraft equipped with thrust vectoring, an assessment of the F-18 HARV maneuvering requirements to assist in thrust vectoring control system design, and an agility assessment of the F-18. The F-18 agility assessment was compared with in-flight testing. Open-loop maneuvers such as 180-deg rolls to measure roll rate showed favorable simulator/in-flight comparison. Closed-loop maneuvers such as rolls to 90 deg with precision stops or certain maximum longitudinal pitching maneuvers showed poorer performance due to reduced aggressiveness of pilot inputs in flight to remain within flight envelope limits.

  17. The AGILE Data Center at ASDC

    NASA Astrophysics Data System (ADS)

    Pittori, Carlotta; AGILE Collaboration

    2013-01-01

    AGILE is a Scientific Mission of the Italian Space Agency (ASI) with INFN, INAF and CIFS participation, devoted to gamma-ray astrophysics. The satellite has been in orbit since April 23rd, 2007. Thanks to its sky monitoring capability and fast ground segment alert system, AGILE produced several important scientific results, among which was the unexpected discovery of strong and rapid gamma-ray flares from the Crab Nebula over daily timescales. This discovery won for the AGILE PI and the AGILE Team the Bruno Rossi Prize for 2012. The AGILE Data Center, located at ASDC, is in charge of all the scientific oriented activities related to the analysis and archiving of AGILE data. I will present the AGILE data center main activities, and I will give an overview of the AGILE scientific highlights after 5 years of operations.

  18. Relationship Between Reactive Agility and Change of Direction Speed in Amateur Soccer Players.

    PubMed

    Matlák, János; Tihanyi, József; Rácz, Levente

    2016-06-01

    Matlák, J, Tihanyi, J, and Rácz, L. Relationship between reactive agility and change of direction speed in amateur soccer players. J Strength Cond Res 30(6): 1547-1552, 2016-The aim of the study was to assess the relationship between reactive agility and change of direction speed (CODS) among amateur soccer players using running tests with four directional changes. Sixteen amateur soccer players (24.1 ± 3.3 years; 72.4 ± 7.3 kg; 178.7 ± 6 cm) completed CODS and reactive agility tests with four changes of direction using the SpeedCourt™ system (Globalspeed GmbH, Hemsbach, Germany). Countermovement jump (CMJ) height and maximal foot tapping count (completed in 3 seconds) were also measured with the same device. In the reactive agility test, participants had to react to a series of light stimuli projected onto a screen. Total time was shorter in the CODS test than in the reactive agility test (p < 0.001). Nonsignificant correlations were found among variables measured in the CODS, reactive agility, and CMJ tests. Low common variance (r = 0.03-0.18) was found between CODS and reactive agility test variables. The results of this study underscore the importance of cognitive factors in reactive agility performance and suggest that specific methods may be required for training and testing reactive agility and CODS. PMID:26562713

  19. Onshore and Offshore Outsourcing with Agility: Lessons Learned

    NASA Astrophysics Data System (ADS)

    Kussmaul, Clifton

    This chapter reflects on case study based an agile distributed project that ran for approximately three years (from spring 2003 to spring 2006). The project involved (a) a customer organization with key personnel distributed across the US, developing an application with rapidly changing requirements; (b) onshore consultants with expertise in project management, development processes, offshoring, and relevant technologies; and (c) an external offsite development team in a CMM-5 organization in southern India. This chapter is based on surveys and discussions with multiple participants. The several years since the project was completed allow greater perspective on both the strengths and weaknesses, since the participants can reflect on the entire life of the project, and compare it to subsequent experiences. Our findings emphasize the potential for agile project management in distributed software development, and the importance of people and interactions, taking many small steps to find and correct errors, and matching the structures of the project and product to support implementation of agility.

  20. Application of multiple-hypothesis tracking to agile beam radar tracking

    NASA Astrophysics Data System (ADS)

    Popoli, Robert F.; Blackman, Samuel S.; Busch, M. T.

    1996-05-01

    This paper describes methods that have been developed for using multiple hypothesis tracking (MHT) for an agile beam radar in the presence of range gate pull off (RGPO) electronic countermeasures (ECM). The paper shows how the agile beam radar allocation logic can be extended to include uncertainty in target position due to data association uncertainty. It also shows how the MHT track score can be modified to reflect target offset from the commanded radar antenna position and how measured SNR is included in the track score. Results from the second Benchmark tracking study are presented. These results show MHT-based allocation to ge highly efficient. The results also show that the system satisfies stringent track maintenance requirements in the presence of RGPO and coincident target maneuvers.

  1. Agile Machining and Inspection Non-Nuclear Report (NNR) Project

    SciTech Connect

    Lazarus, Lloyd

    2009-02-19

    This report is a high level summary of the eight major projects funded by the Agile Machining and Inspection Non-Nuclear Readiness (NNR) project (FY06.0422.3.04.R1). The largest project of the group is the Rapid Response project in which the six major sub categories are summarized. This project focused on the operations of the machining departments that will comprise Special Applications Machining (SAM) in the Kansas City Responsive Infrastructure Manufacturing & Sourcing (KCRIMS) project. This project was aimed at upgrading older machine tools, developing new inspection tools, eliminating Classified Removable Electronic Media (CREM) in the handling of classified Numerical Control (NC) programs by installing the CRONOS network, and developing methods to automatically load Coordinated-Measuring Machine (CMM) inspection data into bomb books and product score cards. Finally, the project personnel leaned perations of some of the machine tool cells, and now have the model to continue this activity.

  2. Utilization of an agility assessment module in analysis and optimization of preliminary fighter configuration

    NASA Technical Reports Server (NTRS)

    Ngan, Angelen; Biezad, Daniel

    1996-01-01

    A study has been conducted to develop and to analyze a FORTRAN computer code for performing agility analysis on fighter aircraft configurations. This program is one of the modules of the NASA Ames ACSYNT (AirCraft SYNThesis) design code. The background of the agility research in the aircraft industry and a survey of a few agility metrics are discussed. The methodology, techniques, and models developed for the code are presented. The validity of the existing code was evaluated by comparing with existing flight test data. A FORTRAN program was developed for a specific metric, PM (Pointing Margin), as part of the agility module. Example trade studies using the agility module along with ACSYNT were conducted using a McDonnell Douglas F/A-18 Hornet aircraft model. Tile sensitivity of thrust loading, wing loading, and thrust vectoring on agility criteria were investigated. The module can compare the agility potential between different configurations and has capability to optimize agility performance in the preliminary design process. This research provides a new and useful design tool for analyzing fighter performance during air combat engagements in the preliminary design.

  3. RFID-Based Critical Path Expert System for Agility Manufacture Process Management

    NASA Astrophysics Data System (ADS)

    Cheng, Haifang; Xiang, Yuli

    This paper presents a critical path expert system for the agility manufacture process management based on radio frequency identification (RFID) technology. The paper explores that the agility manufacture processes can be visible and controllable with RFID. The critical paths or activities can be easily found out and tracked by the RFID tracing technology. And the expert system can optimize the bottle neck of the task process of the agility management with the critical path adjusting and reforming method. Finally, the paper gives a simple application example of the system to discuss how to adjust the critical paths and how to make the process more agility and flexibility with the critical path expert system. With an RFID-based critical path expert system, the agility manufacture process management will be more effective and efficient.

  4. Taking Another Look at the Data Management Life Cycle: Deconstruction, Agile, and Community

    NASA Astrophysics Data System (ADS)

    Young, J. W.; Lenhardt, W. C.; Parsons, M. A.; Benedict, K. K.

    2014-12-01

    The data life cycle has figured prominently in describing the context of digital scientific data stewardship and cyberinfractructure in support of science. There are many different versions of the data life cycle, but they all follow a similar basic pattern: plan, collect, ingest, asses, preserve, discover, and reuse. The process is often interpreted in a fairly linear fashion despite it being a cycle conceptually. More recently at GeoData 2014 and elsewhere, questions have been raised about the utility of the data life cycle as it is currently represented. We are proposing to the community a re-examination of the data life cycle using an agile lens. Our goal is not to deploy agile methods, but to use agile principles as a heuristic to think about how to incorporate data stewardship across the scientific process from proposal stage to research and beyond. We will present alternative conceptualizations of the data life cycle with a goal to solicit feedback and to develop a new model for conceiving and describing the overall data stewardship process. We seek to re-examine past assumptions and shed new light on the challenges and necessity of data stewardship. The ultimate goal is to support new science through enhanced data interoperability, usability, and preservation.

  5. Frequency-agile wireless sensor networks

    NASA Astrophysics Data System (ADS)

    Arms, Steven W.; Townsend, Christopher P.; Churchill, David L.; Hamel, Michael J.; Galbreath, Jacob H.; Mundell, Steven W.

    2004-07-01

    Our goal was to demonstrate a wireless communications system capable of simultaneous, high speed data communications from a variety of sensors. We have previously reported on the design and application of 2 KHz data logging transceiver nodes, however, only one node may stream data at a time, since all nodes on the network use the same communications frequency. To overcome these limitations, second generation data logging transceivers were developed with software programmable radio frequency (RF) communications. Each node contains on-board memory (2 Mbytes), sensor excitation, instrumentation amplifiers with programmable gains & offsets, multiplexer, 16 bit A/D converter, microcontroller, and frequency agile, bi-directional, frequency shift keyed (FSK) RF serial data link. These systems are capable of continuous data transmission from 26 distinct nodes (902-928 MHz band, 75 kbaud). The system was demonstrated in a compelling structural monitoring application. The National Parks Service requested a means for continual monitoring and recording of sensor data from the Liberty Bell during a move to a new location (Philadelphia, October 2003). Three distinct, frequency agile, wireless sensing nodes were used to detect visible crack shear/opening micromotions, triaxial accelerations, and hairline crack tip strains. The wireless sensors proved to be useful in protecting the Liberty Bell.

  6. Agent-based scheduling system to achieve agility

    NASA Astrophysics Data System (ADS)

    Akbulut, Muhtar B.; Kamarthi, Sagar V.

    2000-12-01

    Today's competitive enterprises need to design, develop, and manufacture their products rapidly and inexpensively. Agile manufacturing has emerged as a new paradigm to meet these challenges. Agility requires, among many other things, scheduling and control software systems that are flexible, robust, and adaptive. In this paper a new agent-based scheduling system (ABBS) is developed to meet the challenges of an agile manufacturing system. In ABSS, unlike in the traditional approaches, information and decision making capabilities are distributed among the system entities called agents. In contrast with the most agent-based scheduling systems which commonly use a bidding approach, the ABBS employs a global performance monitoring strategy. A production-rate-based global performance metric which effectively assesses the system performance is developed to assist the agents' decision making process. To test the architecture, an agent-based discrete event simulation software is developed. The experiments performed using the simulation software yielded encouraging results in supporting the applicability of agent-based systems to address the scheduling and control needs of an agile manufacturing system.

  7. The AGILE gamma-ray astronomy mission

    NASA Astrophysics Data System (ADS)

    Mereghetti, S.; Tavani, M.; Argan, A.; Barbiellini, G.; Caraveo, P.; Chen, A.; Cocco, V.; Costa, E.; Di Cocco, G.; Feroci, M.; Labanti, C.; Lapshov, I.; Lipari, P.; Longo, F.; Morselli, A.; Perotti, F.; Picozza, P.; Pittori, C.; Prest, M.; Rubini, A.; Soffitta, P.; Vallazza, E.; Vercellone, S.; Zanello, D.

    2001-09-01

    We describe the AGILE satellite: a unique tool for high-energy astrophysics in the 30 MeV - 50 GeV range before GLAST. The scientific performances of AGILE are comparable to those of EGRET, despite the much smaller weight and dimensions. The AGILE mission will be optimized for the imaging capabilities above 30 MeV and for the study of transient phenomena, complemented by simultaneous monitoring in the hard X-ray band (10 - 40 keV).

  8. Dynamic tumor tracking using the Elekta Agility MLC

    SciTech Connect

    Fast, Martin F. Nill, Simeon Bedford, James L.; Oelfke, Uwe

    2014-11-01

    Purpose: To evaluate the performance of the Elekta Agility multileaf collimator (MLC) for dynamic real-time tumor tracking. Methods: The authors have developed a new control software which interfaces to the Agility MLC to dynamically program the movement of individual leaves, the dynamic leaf guides (DLGs), and the Y collimators (“jaws”) based on the actual target trajectory. A motion platform was used to perform dynamic tracking experiments with sinusoidal trajectories. The actual target positions reported by the motion platform at 20, 30, or 40 Hz were used as shift vectors for the MLC in beams-eye-view. The system latency of the MLC (i.e., the average latency comprising target device reporting latencies and MLC adjustment latency) and the geometric tracking accuracy were extracted from a sequence of MV portal images acquired during irradiation for the following treatment scenarios: leaf-only motion, jaw + leaf motion, and DLG + leaf motion. Results: The portal imager measurements indicated a clear dependence of the system latency on the target position reporting frequency. Deducting the effect of the target frequency, the leaf adjustment latency was measured to be 38 ± 3 ms for a maximum target speed v of 13 mm/s. The jaw + leaf adjustment latency was 53 ± 3 at a similar speed. The system latency at a target position frequency of 30 Hz was in the range of 56–61 ms for the leaves (v ≤ 31 mm/s), 71–78 ms for the jaw + leaf motion (v ≤ 25 mm/s), and 58–72 ms for the DLG + leaf motion (v ≤ 59 mm/s). The tracking accuracy showed a similar dependency on the target position frequency and the maximum target speed. For the leaves, the root-mean-squared error (RMSE) was between 0.6–1.5 mm depending on the maximum target speed. For the jaw + leaf (DLG + leaf) motion, the RMSE was between 0.7–1.5 mm (1.9–3.4 mm). Conclusions: The authors have measured the latency and geometric accuracy of the Agility MLC, facilitating its future use for clinical

  9. On the Biomimetic Design of Agile-Robot Legs

    PubMed Central

    Garcia, Elena; Arevalo, Juan Carlos; Muñoz, Gustavo; Gonzalez-de-Santos, Pablo

    2011-01-01

    The development of functional legged robots has encountered its limits in human-made actuation technology. This paper describes research on the biomimetic design of legs for agile quadrupeds. A biomimetic leg concept that extracts key principles from horse legs which are responsible for the agile and powerful locomotion of these animals is presented. The proposed biomimetic leg model defines the effective leg length, leg kinematics, limb mass distribution, actuator power, and elastic energy recovery as determinants of agile locomotion, and values for these five key elements are given. The transfer of the extracted principles to technological instantiations is analyzed in detail, considering the availability of current materials, structures and actuators. A real leg prototype has been developed following the biomimetic leg concept proposed. The actuation system is based on the hybrid use of series elasticity and magneto-rheological dampers which provides variable compliance for natural motion. From the experimental evaluation of this prototype, conclusions on the current technological barriers to achieve real functional legged robots to walk dynamically in agile locomotion are presented. PMID:22247667

  10. Multiply-agile encryption in high speed communication networks

    SciTech Connect

    Pierson, L.G.; Witzke, E.L.

    1997-05-01

    Different applications have different security requirements for data privacy, data integrity, and authentication. Encryption is one technique that addresses these requirements. Encryption hardware, designed for use in high-speed communications networks, can satisfy a wide variety of security requirements if that hardware is key-agile, robustness-agile and algorithm-agile. Hence, multiply-agile encryption provides enhanced solutions to the secrecy, interoperability and quality of service issues in high-speed networks. This paper defines these three types of agile encryption. Next, implementation issues are discussed. While single-algorithm, key-agile encryptors exist, robustness-agile and algorithm-agile encryptors are still research topics.

  11. The Introduction of Agility into Albania.

    ERIC Educational Resources Information Center

    Smith-Stevens, Eileen J.; Shkurti, Drita

    1998-01-01

    Describes a plan to introduce and achieve a national awareness of agility (and easy entry into the world market) for Albania through the relatively stable higher-education order. Agility's four strategic principles are enriching the customer, cooperating to enhance competitiveness, organizing to master change and uncertainty, and leveraging the…

  12. Network configuration management : paving the way to network agility.

    SciTech Connect

    Maestas, Joseph H.

    2007-08-01

    Sandia networks consist of nearly nine hundred routers and switches and nearly one million lines of command code, and each line ideally contributes to the capabilities of the network to convey information from one location to another. Sandia's Cyber Infrastructure Development and Deployment organizations recognize that it is therefore essential to standardize network configurations and enforce conformance to industry best business practices and documented internal configuration standards to provide a network that is agile, adaptable, and highly available. This is especially important in times of constrained budgets as members of the workforce are called upon to improve efficiency, effectiveness, and customer focus. Best business practices recommend using the standardized configurations in the enforcement process so that when root cause analysis results in recommended configuration changes, subsequent configuration auditing will improve compliance to the standard. Ultimately, this minimizes mean time to repair, maintains the network security posture, improves network availability, and enables efficient transition to new technologies. Network standardization brings improved network agility, which in turn enables enterprise agility, because the network touches all facets of corporate business. Improved network agility improves the business enterprise as a whole.

  13. Wavelength-Agile External-Cavity Diode Laser for DWDM

    NASA Technical Reports Server (NTRS)

    Pilgrim, Jeffrey S.; Bomse, David S.

    2006-01-01

    A prototype external-cavity diode laser (ECDL) has been developed for communication systems utilizing dense wavelength- division multiplexing (DWDM). This ECDL is an updated version of the ECDL reported in Wavelength-Agile External- Cavity Diode Laser (LEW-17090), NASA Tech Briefs, Vol. 25, No. 11 (November 2001), page 14a. To recapitulate: The wavelength-agile ECDL combines the stability of an external-cavity laser with the wavelength agility of a diode laser. Wavelength is modulated by modulating the injection current of the diode-laser gain element. The external cavity is a Littman-Metcalf resonator, in which the zeroth-order output from a diffraction grating is used as the laser output and the first-order-diffracted light is retro-reflected by a cavity feedback mirror, which establishes one end of the resonator. The other end of the resonator is the output surface of a Fabry-Perot resonator that constitutes the diode-laser gain element. Wavelength is selected by choosing the angle of the diffracted return beam, as determined by position of the feedback mirror. The present wavelength-agile ECDL is distinguished by design details that enable coverage of all 60 channels, separated by 100-GHz frequency intervals, that are specified in DWDM standards.

  14. Agile manufacturing and constraints management: a strategic perspective

    NASA Astrophysics Data System (ADS)

    Stratton, Roy; Yusuf, Yahaya Y.

    2000-10-01

    The definition of the agile paradigm has proved elusive and is often viewed as a panacea, in contention with more traditional approaches to operations strategy development and Larkin its own methodology and tools. The Theory of Constraints (TOC) is also poorly understood, as it is commonly solely associated with production planning and control systems and bottleneck management. This paper will demonstrate the synergy between these two approaches together with the Theory of Inventive Problem Solving (TRIZ), and establish how the systematic elimination of trade-offs can support the agile paradigm. Whereas agility is often seen as a trade-off free destination, both TOC and TRIZ may be considered to be route finders, as they comprise methodologies that focus on the identification and elimination of the trade-offs that constrain the purposeful improvement of a system, be it organizational or mechanical. This paper will also show how the TOC thinking process may be combined with the TRIZ knowledge based approach and used in breaking contradictions within agile logistics.

  15. AGILE integration into APC for high mix logic fab

    NASA Astrophysics Data System (ADS)

    Gatefait, M.; Lam, A.; Le Gratiet, B.; Mikolajczak, M.; Morin, V.; Chojnowski, N.; Kocsis, Z.; Smith, I.; Decaunes, J.; Ostrovsky, A.; Monget, C.

    2015-09-01

    mix logic Fab) in term of product and technology portfolio AGILE corrects for up to 120nm of product topography error on process layer with less than 50nm depth of focus Based on tool functionalities delivered by ASML and on high volume manufacturing requirement, AGILE integration is a real challenge. Regarding ST requirements "Automatic AGILE" functionality developed by ASML was not a turnkey solution and a dedicated functionality was needed. A "ST homemade AGILE integration" has been fully developed and implemented within ASML and ST constraints. This paper describes this integration in our Advanced Process Control platform (APC).

  16. Agile hardware and software systems engineering for critical military space applications

    NASA Astrophysics Data System (ADS)

    Huang, Philip M.; Knuth, Andrew A.; Krueger, Robert O.; Garrison-Darrin, Margaret A.

    2012-06-01

    The Multi Mission Bus Demonstrator (MBD) is a successful demonstration of agile program management and system engineering in a high risk technology application where utilizing and implementing new, untraditional development strategies were necessary. MBD produced two fully functioning spacecraft for a military/DOD application in a record breaking time frame and at dramatically reduced costs. This paper discloses the adaptation and application of concepts developed in agile software engineering to hardware product and system development for critical military applications. This challenging spacecraft did not use existing key technology (heritage hardware) and created a large paradigm shift from traditional spacecraft development. The insertion of new technologies and methods in space hardware has long been a problem due to long build times, the desire to use heritage hardware, and lack of effective process. The role of momentum in the innovative process can be exploited to tackle ongoing technology disruptions and allowing risk interactions to be mitigated in a disciplined manner. Examples of how these concepts were used during the MBD program will be delineated. Maintaining project momentum was essential to assess the constant non recurring technological challenges which needed to be retired rapidly from the engineering risk liens. Development never slowed due to tactical assessment of the hardware with the adoption of the SCRUM technique. We adapted this concept as a representation of mitigation of technical risk while allowing for design freeze later in the program's development cycle. By using Agile Systems Engineering and Management techniques which enabled decisive action, the product development momentum effectively was used to produce two novel space vehicles in a fraction of time with dramatically reduced cost.

  17. Agile manufacturing from a statistical perspective

    SciTech Connect

    Easterling, R.G.

    1995-10-01

    The objective of agile manufacturing is to provide the ability to quickly realize high-quality, highly-customized, in-demand products at a cost commensurate with mass production. More broadly, agility in manufacturing, or any other endeavor, is defined as change-proficiency; the ability to thrive in an environment of unpredictable change. This report discusses the general direction of the agile manufacturing initiative, including research programs at the National Institute of Standards and Technology (NIST), the Department of Energy, and other government agencies, but focuses on agile manufacturing from a statistical perspective. The role of statistics can be important because agile manufacturing requires the collection and communication of process characterization and capability information, much of which will be data-based. The statistical community should initiate collaborative work in this important area.

  18. Agile manufacturing prototyping system (AMPS)

    SciTech Connect

    Garcia, P.

    1998-05-09

    The Agile Manufacturing Prototyping System (AMPS) is being integrated at Sandia National Laboratories. AMPS consists of state of the industry flexible manufacturing hardware and software enhanced with Sandia advancements in sensor and model based control; automated programming, assembly and task planning; flexible fixturing; and automated reconfiguration technology. AMPS is focused on the agile production of complex electromechanical parts. It currently includes 7 robots (4 Adept One, 2 Adept 505, 1 Staubli RX90), conveyance equipment, and a collection of process equipment to form a flexible production line capable of assembling a wide range of electromechanical products. This system became operational in September 1995. Additional smart manufacturing processes will be integrated in the future. An automated spray cleaning workcell capable of handling alcohol and similar solvents was added in 1996 as well as parts cleaning and encapsulation equipment, automated deburring, and automated vision inspection stations. Plans for 1997 and out years include adding manufacturing processes for the rapid prototyping of electronic components such as soldering, paste dispensing and pick-and-place hardware.

  19. Agile Data Management with the Global Change Information System

    NASA Astrophysics Data System (ADS)

    Duggan, B.; Aulenbach, S.; Tilmes, C.; Goldstein, J.

    2013-12-01

    We describe experiences applying agile software development techniques to the realm of data management during the development of the Global Change Information System (GCIS), a web service and API for authoritative global change information under development by the US Global Change Research Program. Some of the challenges during system design and implementation have been : (1) balancing the need for a rigorous mechanism for ensuring information quality with the realities of large data sets whose contents are often in flux, (2) utilizing existing data to inform decisions about the scope and nature of new data, and (3) continuously incorporating new knowledge and concepts into a relational data model. The workflow for managing the content of the system has much in common with the development of the system itself. We examine various aspects of agile software development and discuss whether or how we have been able to use them for data curation as well as software development.

  20. Anthropometric factors related to sprint and agility performance in young male soccer players

    PubMed Central

    Mathisen, Gunnar; Pettersen, Svein Arne

    2015-01-01

    Objective To investigate the relationship between anthropometrics and sprint and agility performance and describe the development of sprint (acceleration) and agility performance in 10- to 16-year-old male soccer players. Methods One hundred and thirty-two participants were divided into three age groups, 10–12 years (mean 10.8±0.50), 13–14 years (mean 13.9±0.50), and 15–16 years (mean 15.5±0.24), with assessment of 20 m sprint with 10 m split time and agility performance related to body height and body mass within groups. Results In the 10- to 12-year-olds, there were no significant correlations between height, weight, and the performance variables, except for body mass, which was correlated to 10–20 m sprint (r=0.30). In the 13- to 14-year-olds, body height was significantly correlated with 10 m sprint (r=0.50) and 20 m sprint (r=0.52), as well as 10–20 m sprint (r=0.50) and agility performance (r=0.28). In the 15- to 16-year-old group, body height was correlated to 20 m (r=0.38) and 10–20 m (r=0.45) sprint. Body mass was significantly correlated to 10 m spring (r=0.35) in the 13- to 14-year-olds, as well as 20 m (r=0.33) and 10–20 m (r=0.35) sprint in the 15- to 16-year-olds. Conclusion Height and body mass were significantly correlated with sprint performance in 13- to 16-year-old male soccer players. However, the 10- to 12-year-olds showed no significant relationship between sprint performance and anthropometrics, except for a small correlation in 10–20 m sprint. This may be attributed to maturation, with large differences in body height and body mass due to different patterns in the growth spurt. The agility performance related to anthropometrics was insignificant apart from a moderate correlation in the 13- to 14-year-olds. PMID:26604842

  1. Agile: From Software to Mission System

    NASA Technical Reports Server (NTRS)

    Trimble, Jay; Shirley, Mark H.; Hobart, Sarah Groves

    2016-01-01

    The Resource Prospector (RP) is an in-situ resource utilization (ISRU) technology demonstration mission, designed to search for volatiles at the Lunar South Pole. This is NASA's first near real time tele-operated rover on the Moon. The primary objective is to search for volatiles at one of the Lunar Poles. The combination of short mission duration, a solar powered rover, and the requirement to explore shadowed regions makes for an operationally challenging mission. To maximize efficiency and flexibility in Mission System design and thus to improve the performance and reliability of the resulting Mission System, we are tailoring Agile principles that we have used effectively in ground data system software development and applying those principles to the design of elements of the mission operations system.

  2. Agility and mixed-model furniture production

    NASA Astrophysics Data System (ADS)

    Yao, Andrew C.

    2000-10-01

    The manufacture of upholstered furniture provides an excellent opportunity to analyze the effect of a comprehensive communication system on classical production management functions. The objective of the research is to study the scheduling heuristics that embrace the concepts inherent in MRP, JIT and TQM while recognizing the need for agility in a somewhat complex and demanding environment. An on-line, real-time data capture system provides the status and location of production lots, components, subassemblies for schedule control. Current inventory status of raw material and purchased items are required in order to develop and adhere to schedules. For the large variety of styles and fabrics customers may order, the communication system must provide timely, accurate and comprehensive information for intelligent decisions with respect to the product mix and production resources.

  3. Social Protocols for Agile Virtual Teams

    NASA Astrophysics Data System (ADS)

    Picard, Willy

    Despite many works on collaborative networked organizations (CNOs), CSCW, groupware, workflow systems and social networks, computer support for virtual teams is still insufficient, especially support for agility, i.e. the capability of virtual team members to rapidly and cost efficiently adapt the way they interact to changes. In this paper, requirements for computer support for agile virtual teams are presented. Next, an extension of the concept of social protocol is proposed as a novel model supporting agile interactions within virtual teams. The extended concept of social protocol consists of an extended social network and a workflow model.

  4. Transitioning from Distributed and Traditional to Distributed and Agile: An Experience Report

    NASA Astrophysics Data System (ADS)

    Wildt, Daniel; Prikladnicki, Rafael

    Global companies that experienced extensive waterfall phased plans are trying to improve their existing processes to expedite team engagement. Agile methodologies have become an acceptable path to follow because it comprises project management as part of its practices. Agile practices have been used with the objective of simplifying project control through simple processes, easy to update documentation and higher team iteration over exhaustive documentation, focusing rather on team continuous improvement and aiming to add value to business processes. The purpose of this chapter is to describe the experience of a global multinational company on transitioning from distributed and traditional to distributed and agile. This company has development centers across North America, South America and Asia. This chapter covers challenges faced by the project teams of two pilot projects, including strengths of using agile practices in a globally distributed environment and practical recommendations for similar endeavors.

  5. Agile manufacturing concepts and opportunities in ceramics

    SciTech Connect

    Booth, C.L.; Harmer, M.P.

    1995-08-01

    In 1991 Lehigh University facilitated seminars over a period of 8 months to define manufacturing needs for the 21st century. They concluded that the future will be characterized by rapid changes in technology advances, customer demands, and shifts in market dynamics and coined the term {open_quotes}Agile Manufacturing{close_quotes}. Agile manufacturing refers to the ability to thrive in an environment of constant unpredictable change. Market opportunities are attacked by partnering to form virtual firms to dynamically obtain the required skills for each product opportunity. This paper will describe and compare agile vs. traditional concepts of organization & structure, management policy and ethics, employee environment, product focus, information, and paradigm shift. Examples of agile manufacturing applied to ceramic materials will be presented.

  6. Agile Data Curation at a State Geological Survey

    NASA Astrophysics Data System (ADS)

    Hills, D. J.

    2015-12-01

    State agencies, including geological surveys, are often the gatekeepers for myriad data products essential for scientific research and economic development. For example, the Geological Survey of Alabama (GSA) is mandated to explore for, characterize, and report Alabama's mineral, energy, water, and biological resources in support of economic development, conservation, management, and public policy for the betterment of Alabama's citizens, communities, and businesses. As part of that mandate, the GSA has increasingly been called upon to make our data more accessible to stakeholders. Even as demand for greater data accessibility grows, budgets for such efforts are often small, meaning that agencies must do more for less. Agile software development has yielded efficient, effective products, most often at lower cost and in shorter time. Taking guidance from the agile software development model, the GSA is working towards more agile data management and curation. To date, the GSA's work has been focused primarily on data rescue. By using workflows that maximize clear communication while encouraging simplicity (e.g., maximizing the amount of work not done or that can be automated), the GSA is bringing decades of dark data into the light. Regular checks by the data rescuer with the data provider (or their proxy) provides quality control without adding an overt burden on either party. Moving forward, these workflows will also allow for more efficient and effective data management.

  7. ROADM architectures and technologies for agile optical networks

    NASA Astrophysics Data System (ADS)

    Eldada, Louay A.

    2007-02-01

    We review the different optoelectronic component and module technologies that have been developed for use in ROADM subsystems, and describe their principles of operation, designs, features, advantages, and challenges. We also describe the various needs for reconfigurable optical add/drop switching in agile optical networks. For each network need, we present the different ROADM subsystem architecture options with their pros and cons, and describe the optoelectronic technologies supporting each architecture.

  8. Agility Following the Application of Cold Therapy

    PubMed Central

    Evans, Todd A.; Ingersoll, Christopher; Knight, Kenneth L.; Worrell, Teddy

    1995-01-01

    Cold application is commonly used before strenuous exercise due to its hypalgesic effects. Some have questioned this procedure because of reports that cold may reduce isokinetic torque. However, there have been no investigations of actual physical performance following cold application. The purpose of this study was to determine if a 20-minute ice immersion treatment to the foot and ankle affected the performance of three agility tests: the carioca maneuver, the cocontraction test, and the shuttle run. Twenty-four male athletic subjects were tested during two different treatment sessions following an orientation session. Subjects were tested following a 20-minute 1°C ice immersion treatment to the dominant foot and ankle and 20 minutes of rest. Following each treatment, subjects performed three trials of each agility test, with 30 seconds rest between each trial, and 1 minute between each different agility test. The order in which each subject performed the agility tests was determined by a balanced Latin square. A MANOVA with repeated measures was used to determine if there was an overall significant difference in the agility times recorded between the cold and control treatments and if the order of the treatment sessions affected the scores. Although the mean agility time scores were slightly slower following the cold treatment, cooling the foot and ankle caused no difference in agility times. Also, there was no difference resulting from the treatment orders. We felt that the slightly slower scores may have been a result of tissue stiffness and/or subject's apprehension immediately following the cold treatment. Cold application to the foot and ankle can be used before strenuous exercise without altering agility. Imagesp232-a PMID:16558341

  9. SuperAGILE Services at ASDC

    SciTech Connect

    Preger, B.; Verrecchia, F.; Pittori, C.; Antonelli, L. A.; Giommi, P.; Lazzarotto, F.; Evangelista, Y.

    2008-05-22

    The Italian Space Agency Science Data Center (ASDC) is a facility with several responsibilities including support to all the ASI scientific missions as for management and archival of the data, acting as the interface between ASI and the scientific community and providing on-line access to the data hosted. In this poster we describe the services that ASDC provides for SuperAGILE, in particular the ASDC public web pages devoted to the dissemination of SuperAGILE scientific results. SuperAGILE is the X-Ray imager onboard the AGILE mission, and provides the scientific community with orbit-by-orbit information on the observed sources. Crucial source information including position and flux in chosen energy bands will be reported in the SuperAGILE public web page at ASDC. Given their particular interest, another web page will be dedicated entirely to GRBs and other transients, where new event alerts will be notified and where users will find all the available informations on the GRBs detected by SuperAGILE.

  10. Three `C's of Agile Practice: Collaboration, Co-ordination and Communication

    NASA Astrophysics Data System (ADS)

    Sharp, Helen; Robinson, Hugh

    The importance of collaboration, co-ordination and communication in agile teams is often discussed and rarely disputed. These activities are supported through various practices including pairing, customer collaboration, stand-ups and the planning game. However the mechanisms used to support these activities are sometimes more difficult to pin down. We have been studying agile teams for over a decade, and have found that story cards and the Wall are central to an agile team's activity, and the information they hold and convey is crucial for supporting the team's collaboration and co-ordination activity. However the information captured by these usually physical artefacts pertains mainly to progress rather than to functional dependencies. This latter information is fundamental to any software development, and in a non-agile environment is usually contained in detailed documentation not generally produced in an agile team. Instead, this information resides in their communication and social practices. In this chapter we discuss these three ‘C's of agile development and what we know about how they are supported through story cards and the Wall.

  11. Integrating a distributed, agile, virtual enterprise in the TEAM program

    NASA Astrophysics Data System (ADS)

    Cobb, C. K.; Gray, W. Harvey; Hewgley, Robert E.; Klages, Edward J.; Neal, Richard E.

    1997-01-01

    The technologies enabling agile manufacturing (TEAM) program enhances industrial capability by advancing and deploying manufacturing technologies that promote agility. TEAM has developed a product realization process that features the integration of product design and manufacturing groups. TEAM uses the tools it collects, develops, and integrates in support of the product realization process to demonstrate and deploy agile manufacturing capabilities for three high- priority processes identified by industry: material removal, forming, and electromechanical assembly. In order to provide a proof-of-principle, the material removal process has been addressed first and has been successfully demonstrate din an 'interconnected' mode. An internet-accessible intersite file manager (IFM) application has been deployed to allow geographically distributed TEAM participants to share and distribute information as the product realization process is executed. An automated inspection planning application has been demonstrated, importing a solid model form the IFM, generating an inspection plan and a part program to be used in the inspection process, and then distributing the part program to the inspection site via the IFM. TEAM seeks to demonstrate the material removal process in an integrated mode in June 1997 complete with an object-oriented framework and infrastructure. The current status and future plans for this project are presented here.

  12. Software ``Best'' Practices: Agile Deconstructed

    NASA Astrophysics Data System (ADS)

    Fraser, Steven

    Software “best” practices depend entirely on context - in terms of the problem domain, the system constructed, the software designers, and the “customers” ultimately deriving value from the system. Agile practices no longer have the luxury of “choosing” small non-mission critical projects with co-located teams. Project stakeholders are selecting and adapting practices based on a combina tion of interest, need and staffing. For example, growing product portfolios through a merger or the acquisition of a company exposes legacy systems to new staff, new software integration challenges, and new ideas. Innovation in communications (tools and processes) to span the growth and contraction of both information and organizations, while managing the adoption of changing software practices, is imperative for success. Traditional web-based tools such as web pages, document libraries, and forums are not suf ficient. A blend of tweeting, blogs, wikis, instant messaging, web-based confer encing, and telepresence creates a new dimension of communication “best” practices.

  13. AGILE/GRID Science Alert Monitoring System: The Workflow and the Crab Flare Case

    NASA Astrophysics Data System (ADS)

    Bulgarelli, A.; Trifoglio, M.; Gianotti, F.; Tavani, M.; Conforti, V.; Parmiggiani, N.

    2013-10-01

    During the first five years of the AGILE mission we have observed many gamma-ray transients of Galactic and extragalactic origin. A fast reaction to unexpected transient events is a crucial part of the AGILE monitoring program, because the follow-up of astrophysical transients is a key point for this space mission. We present the workflow and the software developed by the AGILE Team to perform the automatic analysis for the detection of gamma-ray transients. In addition, an App for iPhone will be released enabling the Team to access the monitoring system through mobile phones. In 2010 September the science alert monitoring system presented in this paper recorded a transient phenomena from the Crab Nebula, generating an automated alert sent via email and SMS two hours after the end of an AGILE satellite orbit, i.e. two hours after the Crab flare itself: for this discovery AGILE won the 2012 Bruno Rossi prize. The design of this alert system is maximized to reach the maximum speed, and in this, as in many other cases, AGILE has demonstrated that the reaction speed of the monitoring system is crucial for the scientific return of the mission.

  14. Development of an LC-tandem mass spectrometry method for the separation of montelukast and its application to a pharmacokinetic study in humans.

    PubMed

    Ezzeldin, E; Tammam, M H; AboTalib, N F

    2014-11-01

    Accurate, precise, and sensitive LC-MS/MS assay method for the determination of montelukast (MO) in human plasma samples using gliclazide (GL) as internal standard was developed and applied in pharmacokinetics study.MO extracted by protein precipitation using acetonitrile. Chromatographic separation was carried out using a Agilant Triple quadrupoles mass spectrometer with API source with an Agilant SB- C18 (50×4.6 mm), 1.8 µm particle size column. A mobile phase consisting of acetonitrile: 0.1% formic acid (84:16) was delivered. Calibration curves were linear in the concentration range of (10.00-800.00) ng/ml. The bioanalytical method for determination of MO was successfully applied to assess pharmacokinetics of montelukast. The LLOQ was sensitive enough for detecting terminal phase concentrations of the drug. This study showed that developed method is suitable for MO pharmacokinetic study. PMID:24500731

  15. In-flight simulation of high agility through active control: Taming complexity by design

    NASA Technical Reports Server (NTRS)

    Padfield, Gareth D.; Bradley, Roy

    1993-01-01

    The motivation for research into helicopter agility stems from the realization that marked improvements relative to current operational types are possible, yet there is a dearth of useful criteria for flying qualities at high performance levels. Several research laboratories are currently investing resources in developing second generation airborne rotorcraft simulators. The UK's focus has been the exploitation of agility through active control technology (ACT); this paper reviews the results of studies conducted to date. The conflict between safety and performance in flight research is highlighted and the various forms of safety net to protect against system failures are described. The role of the safety pilot, and the use of actuator and flight envelope limiting are discussed. It is argued that the deep complexity of a research ACT system can only be tamed through a requirement specification assembled using design principles and cast in an operational simulation form. Work along these lines conducted at DRA is described, including the use of the Jackson System Development method and associated Ada simulation.

  16. Gamma-ray Astrophysics with AGILE

    SciTech Connect

    Longo, Francesco |; Tavani, M.; Barbiellini, G.; Argan, A.; Basset, M.; Boffelli, F.; Bulgarelli, A.; Caraveo, P.; Cattaneo, P.; Chen, A.; Costa, E.; Del Monte, E.; Di Cocco, G.; Di Persio, G.; Donnarumma, I.; Feroci, M.; Fiorini, M.; Foggetta, L.; Froysland, T.; Frutti, M.

    2007-07-12

    AGILE will explore the gamma-ray Universe with a very innovative instrument combining for the first time a gamma-ray imager and a hard X-ray imager. AGILE will be operational in spring 2007 and it will provide crucial data for the study of Active Galactic Nuclei, Gamma-Ray Bursts, unidentified gamma-ray sources. Galactic compact objects, supernova remnants, TeV sources, and fundamental physics by microsecond timing. The AGILE instrument is designed to simultaneously detect and image photons in the 30 MeV - 50 GeV and 15 - 45 keV energy bands with excellent imaging and timing capabilities, and a large field of view covering {approx} 1/5 of the entire sky at energies above 30 MeV. A CsI calorimeter is capable of GRB triggering in the energy band 0.3-50 MeV AGILE is now (March 2007) undergoing launcher integration and testing. The PLSV launch is planned in spring 2007. AGILE is then foreseen to be fully operational during the summer of 2007.

  17. Computational Methods Development at Ames

    NASA Technical Reports Server (NTRS)

    Kwak, Dochan; Smith, Charles A. (Technical Monitor)

    1998-01-01

    This viewgraph presentation outlines the development at Ames Research Center of advanced computational methods to provide appropriate fidelity computational analysis/design capabilities. Current thrusts of the Ames research include: 1) methods to enhance/accelerate viscous flow simulation procedures, and the development of hybrid/polyhedral-grid procedures for viscous flow; 2) the development of real time transonic flow simulation procedures for a production wind tunnel, and intelligent data management technology; and 3) the validation of methods and the flow physics study gives historical precedents to above research, and speculates on its future course.

  18. Gamma-ray astrophysics with AGILE

    NASA Astrophysics Data System (ADS)

    Tavani, M.

    2003-09-01

    Gamma-ray astrophysics above 30 MeV will soon be revitalized by a new generation of high-energy detectors in space. We discuss here the AGILE Mission that will be dedicated to gamma-ray astrophysics above 30 MeV during the period 2005-2006. The main characteristics of AGILE are: (1) excellent imaging and monitoring capabilities both in the γ-ray (30 MeV - 30 GeV) and hard X-ray (10-40 keV) energy ranges (reaching an arcminute source positioning), (2) very good timing (improving by three orders of magnitude the instrumental deadtime for γ-ray detection compared to previous instruments), and (3) excellent imaging and triggering capability for Gamma-Ray Bursts. The AGILE scientific program will emphasize a quick response to gamma-ray transients and multiwavelength studies of gamma-ray sources.

  19. SuperAGILE and Gamma Ray Bursts

    SciTech Connect

    Pacciani, Luigi; Costa, Enrico; Del Monte, Ettore; Donnarumma, Immacolata; Evangelista, Yuri; Feroci, Marco; Frutti, Massimo; Lazzarotto, Francesco; Lapshov, Igor; Rubini, Alda; Soffitta, Paolo; Tavani, Marco; Barbiellini, Guido; Mastropietro, Marcello; Morelli, Ennio; Rapisarda, Massimo

    2006-05-19

    The solid-state hard X-ray imager of AGILE gamma-ray mission -- SuperAGILE -- has a six arcmin on-axis angular resolution in the 15-45 keV range, a field of view in excess of 1 steradian. The instrument is very light: 5 kg only. It is equipped with an on-board self triggering logic, image deconvolution, and it is able to transmit the coordinates of a GRB to the ground in real-time through the ORBCOMM constellation of satellites. Photon by photon Scientific Data are sent to the Malindi ground station at every contact. In this paper we review the performance of the SuperAGILE experiment (scheduled for a launch in the middle of 2006), after its first onground calibrations, and show the perspectives for Gamma Ray Bursts.

  20. AGILE observation of a gamma-ray flare from the blazar 3C 279

    NASA Astrophysics Data System (ADS)

    Giuliani, A.; D'Ammando, F.; Vercellone, S.; Vittorini, V.; Chen, A. W.; Donnarumma, I.; Pacciani, L.; Pucella, G.; Trois, A.; Bulgarelli, A.; Longo, F.; Tavani, M.; Tosti, G.; Impiombato, D.; Argan, A.; Barbiellini, G.; Boffelli, F.; Caraveo, P. A.; Cattaneo, P. W.; Cocco, V.; Costa, E.; Del Monte, E.; de Paris, G.; Di Cocco, G.; Evangelista, Y.; Feroci, M.; Fiorini, M.; Fornari, F.; Froysland, T.; Fuschino, F.; Galli, M.; Gianotti, F.; Labanti, C.; Lapshov, Y.; Lazzarotto, F.; Lipari, P.; Marisaldi, M.; Mereghetti, S.; Morselli, A.; Pellizzoni, A.; Perotti, F.; Picozza, P.; Prest, M.; Rapisarda, M.; Rappoldi, A.; Soffitta, P.; Trifoglio, M.; Vallazza, E.; Zambra, A.; Zanello, D.; Cutini, S.; Gasparrini, D.; Pittori, C.; Preger, B.; Santolamazza, P.; Verrecchia, F.; Giommi, P.; Colafrancesco, S.; Salotti, L.

    2009-02-01

    Context: We report the detection by the AGILE satellite of an intense gamma-ray flare from the gamma-ray source 3EG J1255-0549, associated with the Flat Spectrum Radio Quasar 3C 279, during the AGILE pointings towards the Virgo Region on 2007 July 9-13. Aims: The simultaneous optical, X-ray and gamma-ray covering allows us to study the spectral energy distribution (SED) and the theoretical models relative to the mid-July flaring episode. Methods: AGILE observed the source during its Science Performance Verification Phase with its two co-aligned imagers: the Gamma-Ray Imaging Detector (GRID) and the hard X-ray imager (Super-AGILE) sensitive in the 30 MeV-50 GeV and 18-60 keV respectively. During the AGILE observation the source was monitored simultaneously in the optical band by the REM telescope and in the X-ray band by the Swift satellite through 4 target of opportunity observations. Results: During 2007 July 9-13, AGILE-GRID detected gamma-ray emission from 3C 279, with the source at ~2° from the center of the field of view, with an average flux of (210 ± 38) × 10-8 ph cm-2 s-1 for energy above 100 MeV. No emission was detected by Super-AGILE, with a 3-σ upper limit of 10 mCrab. During the observation, which lasted about 4 days, no significative gamma-ray flux variation was observed. Conclusions: The Spectral Energy Distribution is modelled with a homogeneous one-zone Synchrotron Self Compton emission plus the contributions by external Compton scattering of the direct disk radiation and, to a lesser extent, by external Compton scattering of photons from the Broad Line Region.

  1. Development of frequency-agile high-repetition-rate CO{sub 2} DIAL systems for long range chemical remote sensing

    SciTech Connect

    Quick, C.R. Jr.; Fite, C.B.; Foy, B.R.; Jolin, J.; Mietz, D.E.

    1997-11-01

    Issues related to the development of direct detection, long-range CO{sub 2} DIAL systems for chemical detection and identification are presented and discussed including: data handling and display techniques for large, multi-{lambda} data sets, turbulence effects, slant path propagation, and speckle averaging. Data examples from various field campaigns and CO{sub 2} lidar platforms are used to illustrate the issues.

  2. Lean and Agile: An Epistemological Reflection

    ERIC Educational Resources Information Center

    Browaeys, Marie-Joelle; Fisser, Sandra

    2012-01-01

    Purpose: The aim of the paper is to contribute to the discussion of treating the concepts of lean and agile in isolation or combination by presenting an alternative view from complexity thinking on these concepts, considering an epistemological approach to this topic. Design/methodology/approach: The paper adopts an epistemological approach, using…

  3. Wired Widgets: Agile Visualization for Space Situational Awareness

    NASA Astrophysics Data System (ADS)

    Gerschefske, K.; Witmer, J.

    2012-09-01

    Continued advancement in sensors and analysis techniques have resulted in a wealth of Space Situational Awareness (SSA) data, made available via tools and Service Oriented Architectures (SOA) such as those in the Joint Space Operations Center Mission Systems (JMS) environment. Current visualization software cannot quickly adapt to rapidly changing missions and data, preventing operators and analysts from performing their jobs effectively. The value of this wealth of SSA data is not fully realized, as the operators' existing software is not built with the flexibility to consume new or changing sources of data or to rapidly customize their visualization as the mission evolves. While tools like the JMS user-defined operational picture (UDOP) have begun to fill this gap, this paper presents a further evolution, leveraging Web 2.0 technologies for maximum agility. We demonstrate a flexible Web widget framework with inter-widget data sharing, publish-subscribe eventing, and an API providing the basis for consumption of new data sources and adaptable visualization. Wired Widgets offers cross-portal widgets along with a widget communication framework and development toolkit for rapid new widget development, giving operators the ability to answer relevant questions as the mission evolves. Wired Widgets has been applied in a number of dynamic mission domains including disaster response, combat operations, and noncombatant evacuation scenarios. The variety of applications demonstrate that Wired Widgets provides a flexible, data driven solution for visualization in changing environments. In this paper, we show how, deployed in the Ozone Widget Framework portal environment, Wired Widgets can provide an agile, web-based visualization to support the SSA mission. Furthermore, we discuss how the tenets of agile visualization can generally be applied to the SSA problem space to provide operators flexibility, potentially informing future acquisition and system development.

  4. PDS4 - Some Principles for Agile Data Curation

    NASA Astrophysics Data System (ADS)

    Hughes, J. S.; Crichton, D. J.; Hardman, S. H.; Joyner, R.; Algermissen, S.; Padams, J.

    2015-12-01

    PDS4, a research data management and curation system for NASA's Planetary Science Archive, was developed using principles that promote the characteristics of agile development. The result is an efficient system that produces better research data products while using less resources (time, effort, and money) and maximizes their usefulness for current and future scientists. The key principle is architectural. The PDS4 information architecture is developed and maintained independent of the infrastructure's process, application and technology architectures. The information architecture is based on an ontology-based information model developed to leverage best practices from standard reference models for digital archives, digital object registries, and metadata registries and capture domain knowledge from a panel of planetary science domain experts. The information model provides a sharable, stable, and formal set of information requirements for the system and is the primary source for information to configure most system components, including the product registry, search engine, validation and display tools, and production pipelines. Multi-level governance is also allowed for the effective management of the informational elements at the common, discipline, and project level. This presentation will describe the development principles, components, and uses of the information model and how an information model-driven architecture exhibits characteristics of agile curation including early delivery, evolutionary development, adaptive planning, continuous improvement, and rapid and flexible response to change.

  5. Methods For Human Resource Development.

    ERIC Educational Resources Information Center

    Conger, D. Stuart

    A description is provided of the training and counseling materials and methods prepared by the Saskatchewan NewStart and the Training Research and Development Station. Following a brief review of the concept of social inventions, summary descriptions are provided of nine adult education courses. These are: 1) Life Skills, which focuses upon…

  6. ANALYTICAL METHOD DEVELOPMENT FOR PHENOLS

    EPA Science Inventory

    This project focused on the development of an analytical method for the analysis of phenols in drinking water. The need for this project is associated with the recently published Contaminant Candidate List (CCL). The following phenolic compounds are listed on the current CCL, a...

  7. Perspectives on Industrial Innovation from Agilent, HP, and Bell Labs

    NASA Astrophysics Data System (ADS)

    Hollenhorst, James

    2014-03-01

    Innovation is the life blood of technology companies. I will give perspectives gleaned from a career in research and development at Bell Labs, HP Labs, and Agilent Labs, from the point of view of an individual contributor and a manager. Physicists bring a unique set of skills to the corporate environment, including a desire to understand the fundamentals, a solid foundation in physical principles, expertise in applied mathematics, and most importantly, an attitude: namely, that hard problems can be solved by breaking them into manageable pieces. In my experience, hiring managers in industry seldom explicitly search for physicists, but they want people with those skills.

  8. Planning and scheduling for agile manufacturers: The Pantex Process Model

    SciTech Connect

    Kjeldgaard, E.A.; Jones, D.A.; List, G.F.; Tumquist, M.A.

    1998-02-01

    Effective use of resources that are shared among multiple products or processes is critical for agile manufacturing. This paper describes the development and implementation of a computerized model to support production planning in a complex manufacturing system at the Pantex Plant, a US Department of Energy facility. The model integrates two different production processes (nuclear weapon disposal and stockpile evaluation) that use common facilities and personnel at the plant. The two production processes are characteristic of flow-shop and job shop operations. The model reflects the interactions of scheduling constraints, material flow constraints, and the availability of required technicians and facilities. Operational results show significant productivity increases from use of the model.

  9. Production planning tools and techniques for agile manufacturing

    SciTech Connect

    Kjeldgaard, E.A.; Jones, D.A.; List, G.F.; Turnquist, M.A.

    1996-10-01

    Effective use of resources shared among multiple products or processes is critical for agile manufacturing. This paper describes development and implementation of a computerized model to support production planning in a complex manufacturing system at Pantex Plant. The model integrates two different production processes (nuclear weapon dismantlement and stockpile evaluation) which use common facilities and personnel, and reflects the interactions of scheduling constraints, material flow constraints, and resource availability. These two processes reflect characteristics of flow-shop and job-shop operations in a single facility. Operational results from using the model are also discussed.

  10. Impact of emerging technologies on future combat aircraft agility

    NASA Technical Reports Server (NTRS)

    Nguyen, Luat T.; Gilert, William P.

    1990-01-01

    The foreseeable character of future within-visual-range air combat entails a degree of agility which calls for the integration of high-alpha aerodynamics, thrust vectoring, intimate pilot/vehicle interfaces, and advanced weapons/avionics suites, in prospective configurations. The primary technology-development programs currently contributing to these goals are presently discussed; they encompass the F-15 Short Takeoff and Landing/Maneuver Technology Demonstrator Program, the Enhanced Fighter Maneuverability Program, the High Angle-of-Attack Technology Program, and the X-29 Technology Demonstrator Program.

  11. The Southern Argentine Agile Meteor Radar (SAAMER)

    NASA Astrophysics Data System (ADS)

    Janches, Diego

    2014-11-01

    The Southern Argentina Agile Meteor Radar (SAAMER) is a new generation system deployed in Rio Grande, Tierra del Fuego, Argentina (53 S) in May 2008. SAAMER transmits 10 times more power than regular meteor radars, and uses a newly developed transmitting array, which focuses power upward instead of the traditional single-antenna-all-sky configuration. The system is configured such that the transmitter array can also be utilized as a receiver. The new design greatly increases the sensitivity of the radar enabling the detection of large number of particles at low zenith angles. The more concentrated transmitted power enables additional meteor studies besides those typical of these systems based on the detection of specular reflections, such as routine detections of head echoes and non-specular trails, previously only possible with High Power and Large Aperture radars. In August 2010, SAAMER was upgraded to a system capable to determine meteoroid orbital parameters. This was achieved by adding two remote receiving stations approximately 10 km away from the main site in near perpendicular directions. The upgrade significantly expands the science that is achieved with this new radar enabling us to study the orbital properties of the interplanetary dust environment. Because of the unique geographical location, SAAMER allows for additional inter-hemispheric comparison with measurements from Canadian Meteor Orbit Radar, which is geographically conjugate. Initial surveys show, for example, that SAAMER observes a very strong contribution of the South Toroidal Sporadic meteor source, of which limited observational data is available. In addition, SAAMER offers similar unique capabilities for meteor showers and streams studies given the range of ecliptic latitudes that the system enables detailed study of showers at high southern latitudes (e.g July Phoenicids or Puppids complex). Finally, SAAMER is ideal for the deployment of complementary instrumentation in both, permanent

  12. A review of the Technologies Enabling Agile Manufacturing program

    SciTech Connect

    Gray, W.H.; Neal, R.E.; Cobb, C.K.

    1996-10-01

    Addressing a technical plan developed in consideration with major US manufacturers, software and hardware providers, and government representatives, the Technologies Enabling Agile Manufacturing (TEAM) program is leveraging the expertise and resources of industry, universities, and federal agencies to develop, integrate, and deploy leap-ahead manufacturing technologies. One of the TEAM program`s goals is to transition products from design to production faster, more efficiently, and at less cost. TEAM`s technology development strategy also provides all participants with early experience in establishing and working within an electronic enterprise that includes access to high-speed networks and high-performance computing and storage systems. The TEAM program uses the cross-cutting tools it collects, develops, and integrates to demonstrate and deploy agile manufacturing capabilities for three high-priority processes identified by industry: material removal, sheet metal forming, electro-mechanical assembly. This paper reviews the current status of the TEAM program with emphasis upon TEAM`s information infrastructure.

  13. Agile multiple aperture imager receiver development

    NASA Astrophysics Data System (ADS)

    Lees, David E. B.; Dillon, Robert F.

    1990-02-01

    A variety of unconventional imaging schemes have been investigated in recent years that rely on small, unphased optical apertures (subaperture) to measure properties of an incoming optical wavefront and recover images of distant objects without using precisely figured, large aperture optical elements. Such schemes offer several attractive features. They provide the potential to create very lare effective aperture that are expandable over time and can be launched into space in small pieces. Since the subapertures are identical in construction, they may be mass producible at potentially low cost. A preliminary design for a practical low cost optical receiver is presented. The multiple aperture design has high sensitivity, wide field-of-view, and is lightweight. A combination of spectral, temporal, and spatial background suppression are used to achieve daytime operation at low signal levels. Modular packaging to make the number of receiver subapertures conveniently scalable is also presented. The design is appropriate to a ground-base proof-of-concept experiment for long range active speckle imaging.

  14. Space Radiation Transport Methods Development

    NASA Astrophysics Data System (ADS)

    Wilson, J.; Tripathi, R.; Qualls, G.; Cucinotta, F.; Prael, R.; Norbury, J.

    Early space radiation shield code development relied on Monte Carlo methods for proton, neutron and pion transport and made important contributions to the space program. More recently Monte Carlo code LAHET has been upgraded to include high-energy multiple-charged light ions for GCR simulations and continues to be expanded in capability. To compensate for low computational efficiency, Monte Carlo methods have resorted to restricted one-dimensional problems leading to imperfect representations of appropriate boundary conditions. Even so, intensive computational requirements resulted and shield evaluation was made near the end of the design process and resolving shielding issues usually had a negative impact on the design. We evaluate the implications of these common one-dimensional assumptions on the evaluation of the Shuttle internal radiation field. Improved spacecraft shield design requires early entry of radiation constraints into the design process to maximize performance and minimize costs. As a result, we have been investigating high-speed computational procedures to allow shield analysis from the preliminary design concepts to the final design. In particular, we will discuss the progress towards a full three-dimensional and computationally efficient deterministic code for which the current HZETRN evaluates the lowest order asymptotic term. HZETRN is the first deterministic solution to the Boltzmann equation allowing field mapping within the International Space Station (ISS) in tens of minutes using standard Finite Element Method (FEM) geometry common to engineering design practice enabling development of integrated multidisciplinary design optimization methods. A single ray trace in ISS FEM geometry requires 14 milliseconds and severely limits application of Monte Carlo methods to such engineering models. A potential means of improving the Monte Carlo efficiency in coupling to spacecraft geometry is given in terms of reconfigurable computing and could be

  15. Lesson Learned from AGILE and LARES ASI Projects About MATED Data Collection and Post Analysis

    NASA Astrophysics Data System (ADS)

    Carpentiero, Rita; Mrchetti, Ernesto; Natalucci, Silvia; Portelli, Claudio

    2012-07-01

    ASI has managed and collected data on project development of two scientific all-Italian missions: AGILE and LARES. Collection of the Model And Test Effectiveness Database (MATED) data, concerning Project, AIV (Assembly Integration and Verification) and NCR (Non Conformance Report) aspects has been performed by the Italian Space Agency (ASI), using available technical documentation of both AGILE e LARES projects. In this paper some consideration on the needs of 'real time' data collection is made, together with proposal of front end improvement of this tool. In addition a preliminary analysis of MATED effectiveness related to the above ASI projects will be presented in a bottom-up and post verification approach.

  16. A process for the agile product realization of electro-mechanical devices

    SciTech Connect

    Forsythe, C.; Ashby, M.R.; Benavides, G.L.; Diegert, K.V.; Jones, R.E.; Longcope, D.B.; Parratt, S.W.

    1995-09-01

    This paper describes a product realization process developed and demonstrated at Sandia by the A-PRIMED (Agile Product Realization for Innovative Electro MEchanical Devices) project that integrates many of the key components of ``agile manufacturing`` into a complete, design-to-production process. Evidence indicates that the process has reduced the product realization cycle and assured product quality. Products included discriminators for a robotic quick change adapter and for an electronic defense system. These discriminators, built using A-PRIMED, met random vibration requirements and had life cycles that far surpass the performance obtained from earlier efforts.

  17. An Ideal Customer: A Grounded Theory of Requirements Elicitation, Communication and Acceptance on Agile Projects

    NASA Astrophysics Data System (ADS)

    Martin, Angela; Biddle, Robert; Noble, James

    This chapter explores the reality of the customer role - a critical, complex, and demanding role on agile teams. Despite initial difficulties, customers love agile development and would not do it any other way, but they also encountered many difficulties in their day-to-day work. In this chapter we describe the practices that have emerged to ensure the role works effectively and sustainably, and how the role has evolved from an individual to a team. We hope customers will find this chapter helpful in performing their role, and programmers will find it useful to understand the complexities of customer's role on the project.

  18. Space Radiation Transport Methods Development

    NASA Technical Reports Server (NTRS)

    Wilson, J. W.; Tripathi, R. K.; Qualls, G. D.; Cucinotta, F. A.; Prael, R. E.; Norbury, J. W.; Heinbockel, J. H.; Tweed, J.

    2002-01-01

    Improved spacecraft shield design requires early entry of radiation constraints into the design process to maximize performance and minimize costs. As a result, we have been investigating high-speed computational procedures to allow shield analysis from the preliminary design concepts to the final design. In particular, we will discuss the progress towards a full three-dimensional and computationally efficient deterministic code for which the current HZETRN evaluates the lowest order asymptotic term. HZETRN is the first deterministic solution to the Boltzmann equation allowing field mapping within the International Space Station (ISS) in tens of minutes using standard Finite Element Method (FEM) geometry common to engineering design practice enabling development of integrated multidisciplinary design optimization methods. A single ray trace in ISS FEM geometry requires 14 milliseconds and severely limits application of Monte Carlo methods to such engineering models. A potential means of improving the Monte Carlo efficiency in coupling to spacecraft geometry is given in terms of reconfigurable computing and could be utilized in the final design as verification of the deterministic method optimized design.

  19. First GRB detections with the AGILE Minicalorimeter

    SciTech Connect

    Marisaldi, M.; Labanti, C.; Fuschino, F.; Bulgarelli, A.; Gianotti, F.; Trifoglio, M.; Galli, M.; Tavani, M.; Argan, A.

    2008-05-22

    The Minicalorimeter (MCAL) onboard the AGILE satellite is a 1400 cm{sup 2} scintillation detector sensitive in the energy range 0.3-200 MeV. MCAL works both as a slave of the AGILE Silicon Tracker and as an autonomous detector for transient events (BURST mode). A dedicated onboard Burst Search logic scans BURST mode data in search of count rate increase. Peculiar characteristics of the detector are the high energy spectral coverage and a timing resolution of about 2 microseconds. Even if a trigger is not issued, BURST mode data are used to build a broad band energy spectrum (scientific ratemeters) organized in 11 bands for each of the two MCAL detection planes, with a time resolution of 1 second. After the first engineering commissioning phase, following the AGILE launch on 23rd April 2007, between 22nd June and 5th November 2007 eighteen GRBs were detected offline in the scientific ratemeters data, with a detection rate of about one per week. In this paper the capabilities of the detector will be described and an overview of the first detected GRBs will be given.

  20. Reference Values for Anaerobic Performance and Agility in Ambulatory Children and Adolescents with Cerebral Palsy

    ERIC Educational Resources Information Center

    Verschuren, Olaf; Bloemen, Manon; Kruitwagen, Cas; Takken, Tim

    2010-01-01

    Aim: The aim of this study was to provide reference values of anaerobic performance and agility in a group of children and adolescents with spastic cerebral palsy (CP). Method: A total of 300 children (184 males, 116 females) with spastic CP were recruited from 26 rehabilitation centres in six different countries. Of these, 215 were classified at…

  1. Candidate control design metrics for an agile fighter

    NASA Technical Reports Server (NTRS)

    Murphy, Patrick C.; Bailey, Melvin L.; Ostroff, Aaron J.

    1991-01-01

    Success in the fighter combat environment of the future will certainly demand increasing capability from aircraft technology. These advanced capabilities in the form of superagility and supermaneuverability will require special design techniques which translate advanced air combat maneuvering requirements into design criteria. Control design metrics can provide some of these techniques for the control designer. Thus study presents an overview of control design metrics and investigates metrics for advanced fighter agility. The objectives of various metric users, such as airframe designers and pilots, are differentiated from the objectives of the control designer. Using an advanced fighter model, metric values are documented over a portion of the flight envelope through piloted simulation. These metric values provide a baseline against which future control system improvements can be compared and against which a control design methodology can be developed. Agility is measured for axial, pitch, and roll axes. Axial metrics highlight acceleration and deceleration capabilities under different flight loads and include specific excess power measurements to characterize energy meneuverability. Pitch metrics cover both body-axis and wind-axis pitch rates and accelerations. Included in pitch metrics are nose pointing metrics which highlight displacement capability between the nose and the velocity vector. Roll metrics (or torsion metrics) focus on rotational capability about the wind axis.

  2. The Test Equipment of the AGILE Minicalorimeter Prototype

    NASA Astrophysics Data System (ADS)

    Trifoglio, M.; Bulgarelli, A.; Gianotti, F.; Celesti, E.; Di Cocco, G.; Labanti, C.; Mauri, A.; Prest, M.; Vallazza, E.; Froysland, T.

    2004-09-01

    AGILE is an ASI (Italian Space Agency) Small Space Mission for high energy astrophysics in the range 30 MeV - 50 GeV. The AGILE satellite is currently in the C phase and is planned to be launched in 2005. The Payload shall consist of a Tungsten-Silicon Tracker, a CsI Minicalorimeter, an anticoincidence system and a X-Ray detector sensitive in the 10-40 KeV range. The purpose of the Minicalorimeter (MCAL) is twofold. It shall work in conjunction with the Tracker in order to evaluate the energy of the interacting photons, and it shall operate autonomously in the energy range 250KeV-250 MeV for detection of transients and gamma ray burst events and for the measurement of gamma ray background fluctuations. We present the architecture of the Test Equipment we have designed and developed in order to test and verify the MCAL Simplified Electrical Model prototype which has been manufactured in order to validate the design of the MCAL Proto Flight Model.

  3. An Agile Methodology for Implementing Service-Oriented Architecture in Small and Medium Sized Organizations

    ERIC Educational Resources Information Center

    Laidlaw, Gregory

    2013-01-01

    The purpose of this study is to evaluate the use of Lean/Agile principles, using action research to develop and deploy new technology for Small and Medium sized enterprises. The research case was conducted at the Lapeer County Sheriff's Department and involves the initial deployment of a Service Oriented Architecture to alleviate the data…

  4. Wideband Agile Digital Microwave Radiometer

    NASA Technical Reports Server (NTRS)

    Gaier, Todd C.; Brown, Shannon T.; Ruf, Christopher; Gross, Steven

    2012-01-01

    The objectives of this work were to take the initial steps needed to develop a field programmable gate array (FPGA)- based wideband digital radiometer backend (>500 MHz bandwidth) that will enable passive microwave observations with minimal performance degradation in a radiofrequency-interference (RFI)-rich environment. As manmade RF emissions increase over time and fill more of the microwave spectrum, microwave radiometer science applications will be increasingly impacted in a negative way, and the current generation of spaceborne microwave radiometers that use broadband analog back ends will become severely compromised or unusable over an increasing fraction of time on orbit. There is a need to develop a digital radiometer back end that, for each observation period, uses digital signal processing (DSP) algorithms to identify the maximum amount of RFI-free spectrum across the radiometer band to preserve bandwidth to minimize radiometer noise (which is inversely related to the bandwidth). Ultimately, the objective is to incorporate all processing necessary in the back end to take contaminated input spectra and produce a single output value free of manmade signals to minimize data rates for spaceborne radiometer missions. But, to meet these objectives, several intermediate processing algorithms had to be developed, and their performance characterized relative to typical brightness temperature accuracy re quirements for current and future microwave radiometer missions, including those for measuring salinity, soil moisture, and snow pack.

  5. Information Models, Data Requirements, and Agile Data Curation

    NASA Astrophysics Data System (ADS)

    Hughes, John S.; Crichton, Dan; Ritschel, Bernd; Hardman, Sean; Joyner, Ron

    2015-04-01

    The Planetary Data System's next generation system, PDS4, is an example of the successful use of an ontology-based Information Model (IM) to drive the development and operations of a data system. In traditional systems engineering, requirements or statements about what is necessary for the system are collected and analyzed for input into the design stage of systems development. With the advent of big data the requirements associated with data have begun to dominate and an ontology-based information model can be used to provide a formalized and rigorous set of data requirements. These requirements address not only the usual issues of data quantity, quality, and disposition but also data representation, integrity, provenance, context, and semantics. In addition the use of these data requirements during system's development has many characteristics of Agile Curation as proposed by Young et al. [Taking Another Look at the Data Management Life Cycle: Deconstruction, Agile, and Community, AGU 2014], namely adaptive planning, evolutionary development, early delivery, continuous improvement, and rapid and flexible response to change. For example customers can be satisfied through early and continuous delivery of system software and services that are configured directly from the information model. This presentation will describe the PDS4 architecture and its three principle parts: the ontology-based Information Model (IM), the federated registries and repositories, and the REST-based service layer for search, retrieval, and distribution. The development of the IM will be highlighted with special emphasis on knowledge acquisition, the impact of the IM on development and operations, and the use of shared ontologies at multiple governance levels to promote system interoperability and data correlation.

  6. Agile and green manufacturing and super hard coated cutting tools

    SciTech Connect

    Chi-Hung Shen

    1995-12-31

    The paper discusses the global movement towards an agile and green manufacturing environment and their impacts on high volume producers such the automotive industry. In the area of machining, two major shifts are envision (1) proliferation of highly flexible CNC single spindle machining centers to replace conventional dedicated transfer lines and (2) implementation of {open_quotes}dry{close_quotes} machining systems where there are no or minimal use of machining fluids. In order to migrate towards these goals and still remain competitive and profitable, economically viable high performance super hard coated cutting tools must be developed. Machining results with CVD diamond coated tools are presented to illustrate their current capabilities and limitations. Key areas for further research and develop of super hard coating tools will also be discussed.

  7. Combat Agility Management System (CAMS)

    NASA Technical Reports Server (NTRS)

    Skow, Andrew; Porada, William

    1994-01-01

    The proper management of energy becomes a complex task in fighter aircraft which have high angle of attack (AOA) capability. Maneuvers at high AOA are accompanied by high bleed rates (velocity decrease), a characteristic that is usually undesirable in a typical combat arena. Eidetics has developed under NASA SBIR Phase 1 and NAVAIR SBIR Phase 2 contracts a system which allows a pilot to more easily and effectively manage the trade-off of energy (airspeed or altitude) for turn rate while not imposing hard limits on the high AOA nose pointing capability that can be so important in certain air combat maneuver situations. This has been accomplished by incorporating a two-stage angle of attack limiter into the flight control laws. The first stage sets a limit on AOA to achieve a limit on the maximum bleed rate (selectable) by limiting AOA to values which are dependent on the aircraft attitude and dynamic pressure (or flight path, velocity, and altitude). The second stage sets an AOA limit near the AOA for C(sub l max). One of the principal benefits of such a system is that it enables a low-experience pilot to become much more proficient at managing his energy. The Phase 2 simulation work is complete, and an exploratory flight test on the F-18 HARV is planned for the Fall of 1994 to demonstrate/validate the concept.

  8. Scaling Agile Infrastructure to People

    NASA Astrophysics Data System (ADS)

    Jones, B.; McCance, G.; Traylen, S.; Barrientos Arias, N.

    2015-12-01

    When CERN migrated its infrastructure away from homegrown fabric management tools to emerging industry-standard open-source solutions, the immediate technical challenges and motivation were clear. The move to a multi-site Cloud Computing model meant that the tool chains that were growing around this ecosystem would be a good choice, the challenge was to leverage them. The use of open-source tools brings challenges other than merely how to deploy them. Homegrown software, for all the deficiencies identified at the outset of the project, has the benefit of growing with the organization. This paper will examine what challenges there were in adapting open-source tools to the needs of the organization, particularly in the areas of multi-group development and security. Additionally, the increase in scale of the plant required changes to how Change Management was organized and managed. Continuous Integration techniques are used in order to manage the rate of change across multiple groups, and the tools and workflow for this will be examined.

  9. Agile Bodies: A New Imperative in Neoliberal Governance

    ERIC Educational Resources Information Center

    Gillies, Donald

    2011-01-01

    Modern business discourse suggests that a key bulwark against market fluctuation and the threat of failure is for organizations to become "agile'", a more dynamic and proactive position than that previously afforded by mere "flexibility". The same idea is also directed at the personal level, it being argued that the "agile" individual is better…

  10. Integrated product definition representation for agile numerical control applications

    SciTech Connect

    Simons, W.R. Jr.; Brooks, S.L.; Kirk, W.J. III; Brown, C.W.

    1994-11-01

    Realization of agile manufacturing capabilities for a virtual enterprise requires the integration of technology, management, and work force into a coordinated, interdependent system. This paper is focused on technology enabling tools for agile manufacturing within a virtual enterprise specifically relating to Numerical Control (N/C) manufacturing activities and product definition requirements for these activities.

  11. Supply chain network design problem for a new market opportunity in an agile manufacturing system

    NASA Astrophysics Data System (ADS)

    Babazadeh, Reza; Razmi, Jafar; Ghodsi, Reza

    2012-08-01

    The characteristics of today's competitive environment, such as the speed with which products are designed, manufactured, and distributed, and the need for higher responsiveness and lower operational cost, are forcing companies to search for innovative ways to do business. The concept of agile manufacturing has been proposed in response to these challenges for companies. This paper copes with the strategic and tactical level decisions in agile supply chain network design. An efficient mixed-integer linear programming model that is able to consider the key characteristics of agile supply chain such as direct shipments, outsourcing, different transportation modes, discount, alliance (process and information integration) between opened facilities, and maximum waiting time of customers for deliveries is developed. In addition, in the proposed model, the capacity of facilities is determined as decision variables, which are often assumed to be fixed. Computational results illustrate that the proposed model can be applied as a power tool in agile supply chain network design as well as in the integration of strategic decisions with tactical decisions.

  12. Unsteady aerodynamic models for agile flight at low Reynolds numbers

    NASA Astrophysics Data System (ADS)

    Brunton, Steven L.

    This work develops low-order models for the unsteady aerodynamic forces on a wing in response to agile maneuvers at low Reynolds number. Model performance is assessed on the basis of accuracy across a range of parameters and frequencies as well as of computational efficiency and compatibility with existing control techniques and flight dynamic models. The result is a flexible modeling procedure that yields accurate, low-dimensional, state-space models. The modeling procedures are developed and tested on direct numerical simulations of a two-dimensional flat plate airfoil in motion at low Reynolds number, Re=100, and in a wind tunnel experiment at the Illinois Institute of Technology involving a NACA 0006 airfoil pitching and plunging at Reynolds number Re=65,000. In both instances, low-order models are obtained that accurately capture the unsteady aerodynamic forces at all frequencies. These cases demonstrate the utility of the modeling procedure developed in this thesis for obtaining accurate models for different geometries and Reynolds numbers. Linear reduced-order models are constructed from either the indicial response (step response) or realistic input/output maneuvers using a flexible modeling procedure. The method is based on identifying stability derivatives and modeling the remaining dynamics with the eigensystem realization algorithm. A hierarchy of models is developed, based on linearizing the flow at various operating conditions. These models are shown to be accurate and efficient for plunging, pitching about various points, and combined pitch and plunge maneuvers, at various angle of attack and Reynolds number. Models are compared against the classical unsteady aerodynamic models of Wagner and Theodorsen over a large range of Strouhal number and reduced frequency for a baseline comparison. Additionally, state-space representations are developed for Wagner's and Theodorsen's models, making them compatible with modern control-system analysis. A number of

  13. AGILE detection of intense gamma-ray emission from the blazar PKS 1510-089

    NASA Astrophysics Data System (ADS)

    Pucella, G.; Vittorini, V.; D'Ammando, F.; Tavani, M.; Raiteri, C. M.; Villata, M.; Argan, A.; Barbiellini, G.; Boffelli, F.; Bulgarelli, A.; Caraveo, P.; Cattaneo, P. W.; Chen, A. W.; Cocco, V.; Costa, E.; Del Monte, E.; de Paris, G.; Di Cocco, G.; Donnarumma, I.; Evangelista, Y.; Feroci, M.; Fiorini, M.; Froysland, T.; Fuschino, F.; Galli, M.; Gianotti, F.; Giuliani, A.; Labanti, C.; Lapshov, I.; Lazzarotto, F.; Lipari, P.; Longo, F.; Marisaldi, M.; Mereghetti, S.; Morselli, A.; Pacciani, L.; Pellizzoni, A.; Perotti, F.; Picozza, P.; Prest, M.; Rapisarda, M.; Rappoldi, A.; Soffitta, P.; Trifoglio, M.; Trois, A.; Vallazza, E.; Vercellone, S.; Zambra, A.; Zanello, D.; Antonelli, L. A.; Colafrancesco, S.; Cutini, S.; Gasparrini, D.; Giommi, P.; Pittori, C.; Verrecchia, F.; Salotti, L.; Aller, M. F.; Aller, H. D.; Carosati, D.; Larionov, V. M.; Ligustri, R.

    2008-11-01

    Context: We report the detection by the AGILE (Astro-rivelatore Gamma a Immagini LEggero) satellite of an intense gamma-ray flare from the source AGL J1511-0909, associated with the powerful quasar PKS 1510-089, during ten days of observations from 23 August to 1 September 2007. Aims: During the observation period, the source was in optical decrease following a flaring event monitored by the GLAST-AGILE Support Program (GASP) of the Whole Earth Blazar Telescope (WEBT). The simultaneous gamma-ray, optical, and radio coverage allows us to study the spectral energy distribution and the theoretical models based on the synchrotron and inverse Compton (IC) emission mechanisms. Methods: AGILE observed the source with its two co-aligned imagers, the Gamma-Ray Imaging Detector and the hard X-ray imager Super-AGILE sensitive in the 30 MeV div 50 GeV and 18 div 60 keV bands, respectively. Results: Between 23 and 27 August 2007, AGILE detected gamma-ray emission from PKS 1510-089 when this source was located 50° off-axis, with an average flux of (270 ± 65) × 10-8 photons cm-2 s-1 for photon energy above 100 MeV. In the following period, 28 August-1 September, after a satellite re-pointing, AGILE detected the source at 35° off-axis, with an average flux (E > 100 MeV) of (195 ± 30) × 10-8 photons cm-2 s-1. No emission was detected by Super-AGILE, with a 3-σ upper limit of 45 mCrab in 200 ks. Conclusions: The spectral energy distribution is modelled with a homogeneous one-zone synchrotron self Compton (SSC) emission plus contributions by external photons: the SSC emission contributes primarily to the X-ray band, whereas the contribution of the IC from the external disc and the broad line region match the hard gamma-ray spectrum observed.

  14. Agile and dexterous robot for inspection and EOD operations

    NASA Astrophysics Data System (ADS)

    Handelman, David A.; Franken, Gordon H.; Komsuoglu, Haldun

    2010-04-01

    The All-Terrain Biped (ATB) robot is an unmanned ground vehicle with arms, legs and wheels designed to drive, crawl, walk and manipulate objects for inspection and explosive ordnance disposal tasks. This paper summarizes on-going development of the ATB platform. Control technology for semi-autonomous legged mobility and dual-arm dexterity is described as well as preliminary simulation and hardware test results. Performance goals include driving on flat terrain, crawling on steep terrain, walking on stairs, opening doors and grasping objects. Anticipated benefits of the adaptive mobility and dexterity of the ATB platform include increased robot agility and autonomy for EOD operations, reduced operator workload and reduced operator training and skill requirements.

  15. The agile transversal filter - A flexible building block for ICNIA

    NASA Astrophysics Data System (ADS)

    Botha, D. G.; Smead, F. W.

    Integrated Communications, Navigation and Identification Avionics (ICNIA) is an advanced development program to demonstrate an integrated systems approach to the implementation of functions normally performed by a collection of independent black boxes. The system design partitions all CNI functions to optimize modular commonality within the ICNIA system. One function required in many parallel channels is the processing of signals with instantaneous bandwidths of 10 MHz or less. A specific implementation is the Narrow Band Agile Transversal Filter (NBATF), which can be implemented in state-of-the-art technology, can process signals with a variety of algorithms selectable under software control, and can be replicated within the system, as required, to perform the total set of functions. The NBATF constitutes a building block module within the ICNIA system.

  16. Thrust Direction Optimization: Satisfying Dawn's Attitude Agility Constraints

    NASA Technical Reports Server (NTRS)

    Whiffen, Gregory J.

    2013-01-01

    The science objective of NASA's Dawn Discovery mission is to explore the giant asteroid Vesta and the dwarf planet Ceres, the two largest members of the main asteroid belt. Dawn successfully completed its orbital mission at Vesta. The Dawn spacecraft has complex, difficult to quantify, and in some cases severe limitations on its attitude agility. The low-thrust transfers between science orbits at Vesta required very complex time varying thrust directions due to the strong and complex gravity and various science objectives. Traditional low-thrust design objectives (like minimum change in velocity or minimum transfer time) often result in thrust direction time evolutions that cannot be accommodated with the attitude control system available on Dawn. This paper presents several new optimal control objectives, collectively called thrust direction optimization that were developed and turned out to be essential to the successful navigation of Dawn at Vesta.

  17. Thrust Direction Optimization: Satisfying Dawn's Attitude Agility Constraints

    NASA Technical Reports Server (NTRS)

    Whiffen, Gregory J.

    2013-01-01

    The science objective of NASA's Dawn Discovery mission is to explore the two largest members of the main asteroid belt, the giant asteroid Vesta and the dwarf planet Ceres. Dawn successfully completed its orbital mission at Vesta. The Dawn spacecraft has complex, difficult to quantify, and in some cases severe limitations on its attitude agility. The low-thrust transfers between science orbits at Vesta required very complex time varying thrust directions due to the strong and complex gravity and various science objectives. Traditional thrust design objectives (like minimum (Delta)V or minimum transfer time) often result in thrust direction time evolutions that can not be accommodated with the attitude control system available on Dawn. This paper presents several new optimal control objectives, collectively called thrust direction optimization that were developed and necessary to successfully navigate Dawn through all orbital transfers at Vesta.

  18. A new algorithm for agile satellite-based acquisition operations

    NASA Astrophysics Data System (ADS)

    Bunkheila, Federico; Ortore, Emiliano; Circi, Christian

    2016-06-01

    Taking advantage of the high manoeuvrability and the accurate pointing of the so-called agile satellites, an algorithm which allows efficient management of the operations concerning optical acquisitions is described. Fundamentally, this algorithm can be subdivided into two parts: in the first one the algorithm operates a geometric classification of the areas of interest and a partitioning of these areas into stripes which develop along the optimal scan directions; in the second one it computes the succession of the time windows in which the acquisition operations of the areas of interest are feasible, taking into consideration the potential restrictions associated with these operations and with the geometric and stereoscopic constraints. The results and the performances of the proposed algorithm have been determined and discussed considering the case of the Periodic Sun-Synchronous Orbits.

  19. Sensory enhancing insoles improve athletic performance during a hexagonal agility task.

    PubMed

    Miranda, Daniel L; Hsu, Wen-Hao; Gravelle, Denise C; Petersen, Kelsey; Ryzman, Rachael; Niemi, James; Lesniewski-Laas, Nicholas

    2016-05-01

    Athletes incorporate afferent signals from the mechanoreceptors of their plantar feet to provide information about posture, stability, and joint position. Sub-threshold stochastic resonance (SR) sensory enhancing insoles have been shown to improve balance and proprioception in young and elderly participant populations. Balance and proprioception are correlated with improved athletic performance, such as agility. Agility is defined as the ability to quickly change direction. An athlete's agility is commonly evaluated during athletic performance testing to assess their ability to participate in a competitive sporting event. Therefore, the purpose of this study was to examine the effects of SR insoles during a hexagonal agility task routinely used by coaches and sports scientists. Twenty recreational athletes were recruited to participate in this study. Each athlete was asked to perform a set of hexagonal agility trials while SR stimulation was either on or off. Vicon motion capture was used to measure feet position during six successful trials for each stimulation condition. Stimulation condition was randomized in a pairwise fashion. The study outcome measures were the task completion time and the positional accuracy of footfalls. Pairwise comparisons revealed a 0.12s decrease in task completion time (p=0.02) with no change in hopping accuracy (p=0.99) when SR stimulation was on. This is the first study to show athletic performance benefits while wearing proprioception and balance improving equipment on healthy participants. With further development, a self-contained sensory enhancing insole device could be used by recreational and professional athletes to improve movements that require rapid changes in direction. PMID:26944688

  20. Agile Data Curation: A conceptual framework and approach for practitioner data management

    NASA Astrophysics Data System (ADS)

    Young, J. W.; Benedict, K. K.; Lenhardt, W. C.

    2015-12-01

    Data management occurs across a range of science and related activities such as decision-support. Exemplars within the science community operate data management systems that are extensively planned before implementation, staffed with robust data management expertise, equipped with appropriate services and technologies, and often highly structured. However, this is not the only approach to data management and almost certainly not the typical experience. The other end of the spectrum is often an ad hoc practitioner team, with changing requirements, limited training in data management, and resource constrained for both equipment and human resources. Much of the existing data management literature serves the exemplar community and ignores the ad hoc practitioners. Somewhere in the middle are examples where data are repurposed for new uses thereby generating new data management challenges. This submission presents a conceptualization of an Agile Data Curation approach that provides foundational principles for data management efforts operating across the spectrum of data generation and use from large science systems to efforts with constrained resources, limited expertise, and evolving requirements. The underlying principles to Agile Data Curation are a reapplication of agile software development principles to data management. The historical reality for many data management efforts is operating in a practioner environment so Agile Data Curation utilizes historical and current case studies to validate the foundational principles and through comparison learn lessons for future application. This submission will provide an overview of the Agile Data Curation, cover the foundational principles to the approach, and introduce a framework for gathering, classifying, and applying lessons from case studies of practitioner data management.

  1. Advanced probabilistic method of development

    NASA Technical Reports Server (NTRS)

    Wirsching, P. H.

    1987-01-01

    Advanced structural reliability methods are utilized on the Probabilistic Structural Analysis Methods (PSAM) project to provide a tool for analysis and design of space propulsion system hardware. The role of the effort at the University of Arizona is to provide reliability technology support to this project. PSAM computer programs will provide a design tool for analyzing uncertainty associated with thermal and mechanical loading, material behavior, geometry, and the analysis methods used. Specifically, reliability methods are employed to perform sensitivity analyses, to establish the distribution of a critical response variable (e.g., stress, deflection), to perform reliability assessment, and ultimately to produce a design which will minimize cost and/or weight. Uncertainties in the design factors of space propulsion hardware are described by probability models constructed using statistical analysis of data. Statistical methods are employed to produce a probability model, i.e., a statistical synthesis or summary of each design variable in a format suitable for reliability analysis and ultimately, design decisions.

  2. Differentiation of Salmonella strains from the SARA, SARB and SARC reference collections by using three genes PCR-RFLP and the 2100 Agilent Bioanalyzer.

    PubMed

    Soler-García, Angel A; De Jesús, Antonio J; Taylor, Kishana; Brown, Eric W

    2014-01-01

    Rapid molecular typing methods are important tools in surveillance and outbreak investigations of human Salmonella infections. Here we described the development of a three-genes PCR-RFLP typing method for the differentiation of Salmonella species, subspecies and serovars using the Agilent 2100 Bioanalyzer. The fliC, gnd, and mutS genes were PCR-amplified in 160 Salmonella strains representing the two Salmonella species, six subspecies, and 41 different serovars of S. enterica subspecies enterica. PCR products were individually cut with two different restriction enzymes and the resulting 930 restriction patterns were collected using the Agilent 2100 Bioanalyzer followed by cluster analysis. Both species of Salmonella were differentiated by conventional PCR. All of S. bongori tested were gnd PCR negative due to a mismatch at the 3'-end in one the PCR primers. Salmonella subspecies were differentiated into third-teen homogeneous groups representing each of the six subspecies by cluster analysis of restriction patterns generated from the mutS gene cut with AciI. S. enterica subspecies enterica serovars were further differentiated by the combination of the three target genes and five out the six sets of restriction patterns with a discriminatory power of 0.9725 by cluster analysis. The combined RFLP results of five sets of restriction patterns allowed us to assign each of the 160 strains to one of 128 restriction types. During inoculation studies we were able to identify S. Saintpaul and Typhimurium from 24 h pre-enrichment samples using the described method. The use of fliC, gnd, and mutS PCR-RFLP with the Agilent 2100 Bioanalyzer can provide an accessible and automated alternative method for differentiation of Salmonella pathogens. PMID:25157247

  3. Differentiation of Salmonella strains from the SARA, SARB and SARC reference collections by using three genes PCR-RFLP and the 2100 Agilent Bioanalyzer

    PubMed Central

    Soler-García, Ángel A.; De Jesús, Antonio J.; Taylor, Kishana; Brown, Eric W.

    2014-01-01

    Rapid molecular typing methods are important tools in surveillance and outbreak investigations of human Salmonella infections. Here we described the development of a three-genes PCR-RFLP typing method for the differentiation of Salmonella species, subspecies and serovars using the Agilent 2100 Bioanalyzer. The fliC, gnd, and mutS genes were PCR-amplified in 160 Salmonella strains representing the two Salmonella species, six subspecies, and 41 different serovars of S. enterica subspecies enterica. PCR products were individually cut with two different restriction enzymes and the resulting 930 restriction patterns were collected using the Agilent 2100 Bioanalyzer followed by cluster analysis. Both species of Salmonella were differentiated by conventional PCR. All of S. bongori tested were gnd PCR negative due to a mismatch at the 3′-end in one the PCR primers. Salmonella subspecies were differentiated into third-teen homogeneous groups representing each of the six subspecies by cluster analysis of restriction patterns generated from the mutS gene cut with AciI. S. enterica subspecies enterica serovars were further differentiated by the combination of the three target genes and five out the six sets of restriction patterns with a discriminatory power of 0.9725 by cluster analysis. The combined RFLP results of five sets of restriction patterns allowed us to assign each of the 160 strains to one of 128 restriction types. During inoculation studies we were able to identify S. Saintpaul and Typhimurium from 24 h pre-enrichment samples using the described method. The use of fliC, gnd, and mutS PCR-RFLP with the Agilent 2100 Bioanalyzer can provide an accessible and automated alternative method for differentiation of Salmonella pathogens. PMID:25157247

  4. Methods development for electron transport

    NASA Astrophysics Data System (ADS)

    Ganapol, Barry D.

    1992-04-01

    This report consists of two code manuals and an article recently published in the proceedings of the American Nuclear Society Mathematics and Computation Topical Meeting held in Pittsburgh. In these presentations, deterministic calculational methods simulating electron transport in solids are detailed. The first method presented (Section 2) is for the solution of the Spencer-Lewis equation in which electron motion is characterized by continuous slowing down theory and a pathlength formulation. The FN solution to the standard monoenergetic transport equation for electron transport with isotropic scattering in finite media is given in Section 3. For both codes, complete flow charts, operational instructions and sample problems are included. Finally, in Section 4, an application of the multigroup formulation of electron transport in an infinite medium is used to verify an equivalent SN formulation. For this case, anisotropic scattering is also included.

  5. Search of MeV-GeV counterparts of TeV sources with AGILE in pointing mode

    NASA Astrophysics Data System (ADS)

    Rappoldi, A.; Lucarelli, F.; Pittori, C.; Longo, F.; Cattaneo, P. W.; Verrecchia, F.; Tavani, M.; Bulgarelli, A.; Chen, A. W.; Colafrancesco, S.; Donnarumma, I.; Giuliani, A.; Morselli, A.; Sabatini, S.; Vercellone, S.

    2016-03-01

    Context. Known TeV sources detected by major Čerenkov telescopes are investigated to identify possible MeV-GeV γ-ray counterparts. Aims: A systematic study of the known sources in the web-based TeVCat catalog has been performed to search for possible γ-ray counterparts on the AGILE data collected during the first period of operations in observing pointing mode. Methods: For each TeV source, a search for a possible γ-ray counterpart that is based on a multi-source maximum likelihood algorithm is performed on the AGILE data taken with the GRID instrument from July 2007 to October 2009. Results: In the case of high-significance detection, the average γ-ray flux is estimated. For cases of low-significance detection the 95% confidence level (CL) flux upper limit is given. 52 TeV sources out of 152 (corresponding to ~34% of the analysed sample) show a significant excess in the AGILE data covering the pointing observation period. Conclusions: This analysis found 26 new AGILE sources with respect to the AGILE reference catalogs, 15 of which are galactic, 7 are extragalactic and 4 are unidentified. Detailed tables with all available information on the analysed sources are presented. An interactive online version of the considered source list including all the analysis results is also available at the website http://www.asdc.asi.it/agiletevcat/

  6. Compact, flexible, frequency agile parametric wavelength converter

    DOEpatents

    Velsko, Stephan P.; Yang, Steven T.

    2002-01-01

    This improved Frequency Agile Optical Parametric Oscillator provides near on-axis pumping of a single QPMC with a tilted periodically poled grating to overcome the necessity to find a particular crystal that will permit collinear birefringence in order to obtain a desired tuning range. A tilted grating design and the elongation of the transverse profile of the pump beam in the angle tuning plane of the FA-OPO reduces the rate of change of the overlap between the pumped volume in the crystal and the resonated and non-resonated wave mode volumes as the pump beam angle is changed. A folded mirror set relays the pivot point for beam steering from a beam deflector to the center of the FA-OPO crystal. This reduces the footprint of the device by as much as a factor of two over that obtained when using the refractive telescope design.

  7. An Examination of an Information Security Framework Implementation Based on Agile Values to Achieve Health Insurance Portability and Accountability Act Security Rule Compliance in an Academic Medical Center: The Thomas Jefferson University Case Study

    ERIC Educational Resources Information Center

    Reis, David W.

    2012-01-01

    Agile project management is most often examined in relation to software development, while information security frameworks are often examined with respect to certain risk management capabilities rather than in terms of successful implementation approaches. This dissertation extended the study of both Agile project management and information…

  8. Effective speed and agility conditioning methodology for random intermittent dynamic type sports.

    PubMed

    Bloomfield, Jonathan; Polman, Remco; O'Donoghue, Peter; McNaughton, Lars

    2007-11-01

    Different coaching methods are often used to improve performance. This study compared the effectiveness of 2 methodologies for speed and agility conditioning for random, intermittent, and dynamic activity sports (e.g., soccer, tennis, hockey, basketball, rugby, and netball) and the necessity for specialized coaching equipment. Two groups were delivered either a programmed method (PC) or a random method (RC) of conditioning with a third group receiving no conditioning (NC). PC participants used the speed, agility, quickness (SAQ) conditioning method, and RC participants played supervised small-sided soccer games. PC was also subdivided into 2 groups where participants either used specialized SAQ equipment or no equipment. A total of 46 (25 males and 21 females) untrained participants received (mean +/- SD) 12.2 +/- 2.1 hours of physical conditioning over 6 weeks between a battery of speed and agility parameter field tests. Two-way analysis of variance results indicated that both conditioning groups showed a significant decrease in body mass and body mass index, although PC achieved significantly greater improvements on acceleration, deceleration, leg power, dynamic balance, and the overall summation of % increases when compared to RC and NC (p < 0.05). PC in the form of SAQ exercises appears to be a superior method for improving speed and agility parameters; however, this study found that specialized SAQ equipment was not a requirement to observe significant improvements. Further research is required to establish whether these benefits transfer to sport-specific tasks as well as to the underlying mechanisms resulting in improved performance. PMID:18076227

  9. Computer vision challenges and technologies for agile manufacturing

    NASA Astrophysics Data System (ADS)

    Molley, Perry A.

    1996-02-01

    Sandia National Laboratories, a Department of Energy laboratory, is responsible for maintaining the safety, security, reliability, and availability of the nuclear weapons stockpile for the United States. Because of the changing national and global political climates and inevitable budget cuts, Sandia is changing the methods and processes it has traditionally used in the product realization cycle for weapon components. Because of the increasing age of the nuclear stockpile, it is certain that the reliability of these weapons will degrade with time unless eventual action is taken to repair, requalify, or renew them. Furthermore, due to the downsizing of the DOE weapons production sites and loss of technical personnel, the new product realization process is being focused on developing and deploying advanced automation technologies in order to maintain the capability for producing new components. The goal of Sandia's technology development program is to create a product realization environment that is cost effective, has improved quality and reduced cycle time for small lot sizes. The new environment will rely less on the expertise of humans and more on intelligent systems and automation to perform the production processes. The systems will be robust in order to provide maximum flexibility and responsiveness for rapidly changing component or product mixes. An integrated enterprise will allow ready access to and use of information for effective and efficient product and process design. Concurrent engineering methods will allow a speedup of the product realization cycle, reduce costs, and dramatically lessen the dependency on creating and testing physical prototypes. Virtual manufacturing will allow production processes to be designed, integrated, and programed off-line before a piece of hardware ever moves. The overriding goal is to be able to build a large variety of new weapons parts on short notice. Many of these technologies that are being developed are also

  10. GRB 070724B: the first Gamma Ray Burst localized by SuperAGILE

    SciTech Connect

    Del Monte, E.; Costa, E.; Donnarumma, I.; Feroci, M.; Lapshov, I.; Lazzarotto, F.; Soffitta, P.; Argan, A.; Pucella, G.; Trois, A.; Vittorini, V.; Evangelista, Y.; Rapisarda, M.; Barbiellini, G.; Longo, F.; Basset, M.; Foggetta, L.; Vallazza, E.; Bulgarelli, A.; Di Cocco, G.

    2008-05-22

    GRB070724B is the first Gamma Ray Burst localized by the SuperAGILE instrument aboard the AGILE space mission. The SuperAGILE localization has been confirmed after the after-glow observation by the XRT aboard the Swift satellite. No significant gamma ray emission above 50 MeV has been detected for this GRB. In this paper we describe the SuperAGILE capabilities in detecting Gamma Ray Burst and the AGILE observation of GRB 070724B.

  11. Agile data management for curation of genomes to watershed datasets

    NASA Astrophysics Data System (ADS)

    Varadharajan, C.; Agarwal, D.; Faybishenko, B.; Versteeg, R.

    2015-12-01

    A software platform is being developed for data management and assimilation [DMA] as part of the U.S. Department of Energy's Genomes to Watershed Sustainable Systems Science Focus Area 2.0. The DMA components and capabilities are driven by the project science priorities and the development is based on agile development techniques. The goal of the DMA software platform is to enable users to integrate and synthesize diverse and disparate field, laboratory, and simulation datasets, including geological, geochemical, geophysical, microbiological, hydrological, and meteorological data across a range of spatial and temporal scales. The DMA objectives are (a) developing an integrated interface to the datasets, (b) storing field monitoring data, laboratory analytical results of water and sediments samples collected into a database, (c) providing automated QA/QC analysis of data and (d) working with data providers to modify high-priority field and laboratory data collection and reporting procedures as needed. The first three objectives are driven by user needs, while the last objective is driven by data management needs. The project needs and priorities are reassessed regularly with the users. After each user session we identify development priorities to match the identified user priorities. For instance, data QA/QC and collection activities have focused on the data and products needed for on-going scientific analyses (e.g. water level and geochemistry). We have also developed, tested and released a broker and portal that integrates diverse datasets from two different databases used for curation of project data. The development of the user interface was based on a user-centered design process involving several user interviews and constant interaction with data providers. The initial version focuses on the most requested feature - i.e. finding the data needed for analyses through an intuitive interface. Once the data is found, the user can immediately plot and download data

  12. Frequency agile OPO-based transmitters for multiwavelength DIAL

    SciTech Connect

    Velsko, S.P.; Ruggiero, A.; Herman, M.

    1996-09-01

    We describe a first generation mid-infrared transmitter with pulse to pulse frequency agility and both wide and narrow band capability. This transmitter was used to make multicomponent Differential Absorption LIDAR (DIAL) measurements in the field.

  13. GIS Method for Developing Wind Supply Curves

    SciTech Connect

    Kline, D.; Heimiller, D.; Cowlin, S.

    2008-06-01

    This report describes work conducted by the National Renewable Energy Laboratory (NREL) as part of the Wind Technology Partnership (WTP) sponsored by the U.S. Environmental Protection Agency (EPA). This project has developed methods that the National Development and Reform Commission (NDRC) intends to use in the planning and development of China's 30 GW of planned capacity. Because of China's influence within the community of developing countries, the methods and the approaches here may help foster wind development in other countries.

  14. Autonomous, agile micro-satellites and supporting technologies

    SciTech Connect

    Breitfeller, E; Dittman, M D; Gaughan, R J; Jones, M S; Kordas, J F; Ledebuhr, A G; Ng, L C; Whitehead, J C; Wilson, B

    1999-07-19

    This paper updates the on-going effort at Lawrence Livermore National Laboratory to develop autonomous, agile micro-satellites (MicroSats). The objective of this development effort is to develop MicroSats weighing only a few tens of kilograms, that are able to autonomously perform precision maneuvers and can be used telerobotically in a variety of mission modes. The required capabilities include satellite rendezvous, inspection, proximity-operations, docking, and servicing. The MicroSat carries an integrated proximity-operations sensor-suite incorporating advanced avionics. A new self-pressurizing propulsion system utilizing a miniaturized pump and non-toxic mono-propellant hydrogen peroxide was successfully tested. This system can provide a nominal 25 kg MicroSat with 200-300 m/s delta-v including a warm-gas attitude control system. The avionics is based on the latest PowerPC processor using a CompactPCI bus architecture, which is modular, high-performance and processor-independent. This leverages commercial-off-the-shelf (COTS) technologies and minimizes the effects of future changes in processors. The MicroSat software development environment uses the Vx-Works real-time operating system (RTOS) that provides a rapid development environment for integration of new software modules, allowing early integration and test. We will summarize results of recent integrated ground flight testing of our latest non-toxic pumped propulsion MicroSat testbed vehicle operated on our unique dynamic air-rail.

  15. The impact of flying qualities on helicopter operational agility

    NASA Technical Reports Server (NTRS)

    Padfield, Gareth D.; Lappos, Nick; Hodgkinson, John

    1993-01-01

    Flying qualities standards are formally set to ensure safe flight and therefore reflect minimum, rather than optimum, requirements. Agility is a flying quality but relates to operations at high, if not maximum, performance. While the quality metrics and test procedures for flying, as covered for example in ADS33C, may provide an adequate structure to encompass agility, they do not currently address flight at high performance. This is also true in the fixed-wing world and a current concern in both communities is the absence of substantiated agility criteria and possible conflicts between flying qualities and high performance. AGARD is sponsoring a working group (WG19) title 'Operational Agility' that deals with these and a range of related issues. This paper is condensed from contributions by the three authors to WG19, relating to flying qualities. Novel perspectives on the subject are presented including the agility factor, that quantifies performance margins in flying qualities terms; a new parameter, based on maneuver acceleration is introduced as a potential candidate for defining upper limits to flying qualities. Finally, a probabilistic analysis of pilot handling qualities ratings is presented that suggests a powerful relationship between inherent airframe flying qualities and operational agility.

  16. Frequency-agile terahertz-wave parametric oscillator in a ring-cavity configuration

    NASA Astrophysics Data System (ADS)

    Minamide, Hiroaki; Ikari, Tomofumi; Ito, Hiromasa

    2009-12-01

    We demonstrate a frequency-agile terahertz wave parametric oscillator (TPO) in a ring-cavity configuration (ring-TPO). The TPO consists of three mirrors and a MgO:LiNbO3 crystal under noncollinear phase-matching conditions. A novel, fast frequency-tuning method was realized by controlling a mirror of the three-mirror ring cavity. The wide tuning range between 0.93 and 2.7 THz was accomplished. For first demonstration using the ring-TPO, terahertz spectroscopy was performed as the verification of the frequency-agile performance, measuring the transmission spectrum of the monosaccharide glucose. The spectrum was obtained within about 8 s in good comparison to those of Fourier transform infrared spectrometer.

  17. A Highly Agile Ground Assessment Robot (HAGAR) for military battlefield and support missions

    SciTech Connect

    Klarer, P.

    1994-04-01

    A mobile robotic vehicle with potential for use in military field applications is described. Based on a Sandia design intended for use in exploration of the Lunar surface, the Highly Agile Ground Assessment Robot (HAGAR) is a four wheeled all-wheel-drive dual-body vehicle. A uniquely simple method of chassis articulation is employed which allows all four wheels to remain in contact with the ground, even while operating in very rough terrain and climbing over obstacles as large as a wheel diameter. Skid steering and modular construction are used to produce a simple, rugged, lightweight, highly agile mobility chassis with a reduction in the number of parts required when compared to conventional vehicle designs for military battlefield and support missions. The design configuration, mobility parameters, potential mission configurations, and performance of existing and proposed HAGAR prototypes are discussed.

  18. TEMPERATURE SCENARIO DEVELOPMENT USING REGRESSION METHODS

    EPA Science Inventory

    A method of developing scenarios of future temperature conditions resulting from climatic change is presented. he method is straightforward and can be used to provide information about daily temperature variations and diurnal ranges, monthly average high, and low temperatures, an...

  19. SU-E-T-149: Electron Beam Profile Differences Between Elekta MLCi2 and Elekta Agility Treatment Heads

    SciTech Connect

    Wu, C; Hatcher, C

    2014-06-01

    Purpose: To report and investigate observed differences in electron beam profiles at various energies/applicators between Elekta MLCi2 and Agility treatment head on Elekta Infinity LINAC Methods: When we upgraded from MLCi2 to Agility on one of our Elekta Infinity LINAC's, electron beam PDDs and profiles were acquired for comparison purpose. All clinical electron energies (6/9/12/15/12/18 MeV) and electron applicators (6/10/14/20/25 square) were included in measurement. PDDs were acquired at 100 SSD in water (PTW MP3 water tank) with a plane-parallel ion chamber (PTW Roos). X and Y Profiles were acquired using IC Profiler (Sun Nuclear Corp.) at 1cm and maximum PDD depths (water equivalent). Results: All PDD curves match very well between MLCi2 and Agility treatment head. However, some significant differences on electron profiles were found. On Agility, even after increasing the default auto-tracking offset values for backup diaphragms in Y and MLC in X by 2.8 cm (the maximum allowed change is 3.0 cm), electron profiles still have rounder shoulders comparing to corresponding MLCi2 profiles. This difference is significantly more pronounced at larger applicators (20 and 25 square), for all electron energies. Conclusion: The significant design change between MLCi2 and Agility beam limiting device seems to affect exit electron beam profiles. In IEC1217 X direction, the main change on Agility is the removal of the original MLCi2 X backup diaphragms and replacing it with MLC leaves; In Y direction, the main change is the radius and materials on Y backup diaphragms.

  20. Frequency-Agile Differential Cavity Ring-Down Spectroscopy

    NASA Astrophysics Data System (ADS)

    Reed, Zachary; Hodges, Joseph

    2015-06-01

    The ultimate precision of highly sensitive cavity-enhanced spectroscopic measurements is often limited by interferences (etalons) caused by weak coupled-cavity effects. Differential measurements of ring-down decay constants have previously been demonstrated to largely cancel these effects, but the measurement acquisition rates were relatively low [1,2]. We have previously demonstrated the use of frequency agile rapid scanning cavity ring-down spectroscopy (FARS-CRDS) for acquisition of absorption spectra [3]. Here, the method of rapidly scanned, frequency-agile differential cavity ring-down spectroscopy (FADS-CRDS) is presented for reducing the effect of these interferences and other shot-to-shot statistical variations in measured decay times. To this end, an electro-optic phase modulator (EOM) with a bandwidth of 20 GHz is driven by a microwave source, generating pairs of sidebands on the probe laser. The optical resonator acts as a highly selective optical filter to all laser frequencies except for one tunable sideband. This sideband may be stepped arbitrarily from mode-to-mode of the ring-down cavity, at a rate limited only by the cavity buildup/decay time. The ability to probe any cavity mode across the EOM bandwidth enables a variety of methods for generating differential spectra. The differential mode spacing may be changed, and the effect of this method on suppressing the various coupled-cavity interactions present in the system is discussed. Alternatively, each mode may also be differentially referenced to a single point, providing immunity to temporal variations in the base losses of the cavity while allowing for conventional spectral fitting approaches. Differential measurements of absorption are acquired at 3.3 kHz and a minimum detectable absorption coefficient of 5 x10-12 cm-1 in 1 s averaging time is achieved. 1. J. Courtois, K. Bielska, and J.T Hodges J. Opt. Soc. Am. B, 30, 1486-1495, 2013 2. H.F. Huang and K.K. Lehmann App. Optics 49, 1378

  1. Agile micromirrors with three degrees of freedom manufactured with liquid MEMS technology

    NASA Astrophysics Data System (ADS)

    Feinerman, Alan D.; Friedman, Gary; Kasman, Elina; Montgomery, Jonathan; Patel, Pancham R.; Megaridis, Constantine; Howell, Eric; Collicott, Steven H.

    2002-01-01

    The Mesoscopic MEMS (MicroElectroMechanical Systems) technology developed at UIC allows the fabrication of structures not possible with conventional planar thin film patterning methods. These techniques enable the fabrication of an agile micro-mirror that can rapidly tip and tilt by large angles in two independent directions with a small footprint on the substrate. The mirrors can be electrostatically deflected, and rotate around a spherical pivot that is a drop of a conducting liquid. The drop can be forced to spread by applying a small voltage to an electrode surrounding the drop and this provides piston motion for the third degree of freedom. The drop is confined to a lithographically defined wetting area on the mirror and the substrate surfaces. The drop provides a surface tension restoring force to balance the electrostatic torque, as well as electrical and thermal conduction between the mirror and the substrate. The fabrication method uses aligned shadow masks to deposit electrodes on a non-planar substrate. The fabrication requires precision dispensing of approximately 10 pL liquid drops using inkjet printing technology.

  2. Properties of terrestrial gamma ray flashes detected by AGILE MCAL below 30 MeV

    NASA Astrophysics Data System (ADS)

    Marisaldi, M.; Fuschino, F.; Tavani, M.; Dietrich, S.; Price, C.; Galli, M.; Pittori, C.; Verrecchia, F.; Mereghetti, S.; Cattaneo, P. W.; Colafrancesco, S.; Argan, A.; Labanti, C.; Longo, F.; Del Monte, E.; Barbiellini, G.; Giuliani, A.; Bulgarelli, A.; Campana, R.; Chen, A.; Gianotti, F.; Giommi, P.; Lazzarotto, F.; Morselli, A.; Rapisarda, M.; Rappoldi, A.; Trifoglio, M.; Trois, A.; Vercellone, S.

    2014-02-01

    We present the characteristics of 308 terrestrial gamma ray flashes (TGFs) detected by the Minicalorimeter (MCAL) instrument on board the AGILE satellite during the period March 2009-July 2012 in the ±2.5° latitude band and selected to have the maximum photon energy up to 30 MeV. The characteristics of the AGILE events are analyzed and compared to the observational framework established by the two other currently active missions capable of detecting TGFs from space, RHESSI and Fermi. A detailed model of the MCAL dead time is presented, which is fundamental to properly interpret our observations. The most significant contribution to dead time is due to the anticoincidence shield in its current configuration and not to the MCAL detector itself. Longitude and local time distributions are compatible with previous observations, while the duration distribution is biased toward longer values because of dead time. The intensity distribution is compatible with previous observations, when dead time is taken into account. The TGFs cumulative spectrum supports a low production altitude, in agreement with previous measurements. We also compare our sample to lightning sferics detected by the World Wide Lightning Location Network and suggest a new method to assess quantitatively the consistency of two TGF populations based on the comparison of the associated lightning activity. According to this method, AGILE and RHESSI samples are compatible with the same parent population. The AGILE TGF catalog below 30 MeV is accessible online at the website of the ASI Science Data Center http://www.asdc.asi.it/mcaltgfcat/.

  3. Agile based "Semi-"Automated Data ingest process : ORNL DAAC example

    NASA Astrophysics Data System (ADS)

    Santhana Vannan, S. K.; Beaty, T.; Cook, R. B.; Devarakonda, R.; Hook, L.; Wei, Y.; Wright, D.

    2015-12-01

    The ORNL DAAC archives and publishes data and information relevant to biogeochemical, ecological, and environmental processes. The data archived at the ORNL DAAC must be well formatted, self-descriptive, and documented, as well as referenced in a peer-reviewed publication. The ORNL DAAC ingest team curates diverse data sets from multiple data providers simultaneously. To streamline the ingest process, the data set submission process at the ORNL DAAC has been recently updated to use an agile process and a semi-automated workflow system has been developed to provide a consistent data provider experience and to create a uniform data product. The goals of semi-automated agile ingest process are to: 1.Provide the ability to track a data set from acceptance to publication 2. Automate steps that can be automated to improve efficiencies and reduce redundancy 3.Update legacy ingest infrastructure 4.Provide a centralized system to manage the various aspects of ingest. This talk will cover the agile methodology, workflow, and tools developed through this system.

  4. Frequency-agile, rapid scanning spectroscopy

    NASA Astrophysics Data System (ADS)

    Truong, G.-W.; Douglass, K. O.; Maxwell, S. E.; van Zee, R. D.; Plusquellic, D. F.; Hodges, J. T.; Long, D. A.

    2013-07-01

    Challenging applications in trace gas measurements require low uncertainty and high acquisition rates. Many cavity-enhanced spectroscopies exhibit significant sensitivity and potential, but their scanning rates are limited by reliance on either mechanical or thermal frequency tuning. Here, we present frequency-agile, rapid scanning spectroscopy (FARS) in which a high-bandwidth electro-optic modulator steps a selected laser sideband to successive optical cavity modes. This approach involves no mechanical motion and allows for a scanning rate of 8 kHz per cavity mode, a rate that is limited only by the cavity response time itself. Unlike rapidly frequency-swept techniques, FARS does not reduce the measurement duty cycle, degrade the spectrum's frequency axis or require an unusual cavity configuration. FARS allows for a sensitivity of ~2 × 10-12 cm-1 Hz-1/2 and a tuning range exceeding 70 GHz. This technique shows promise for fast and sensitive trace gas measurements and studies of chemical kinetics.

  5. Frequency-agile dual-comb spectroscopy

    NASA Astrophysics Data System (ADS)

    Millot, Guy; Pitois, Stéphane; Yan, Ming; Hovhannisyan, Tatevik; Bendahmane, Abdelkrim; Hänsch, Theodor W.; Picqué, Nathalie

    2016-01-01

    Spectroscopic gas sensing and its applications to, for example, trace detection or chemical kinetics, require ever more demanding measurement times, acquisition rates, sensitivities, precisions and broad tuning ranges. Here, we propose a new approach to near-infrared molecular spectroscopy, utilizing advanced concepts of optical telecommunications and supercontinuum photonics. We generate, without mode-locked lasers, two frequency combs of slightly different repetition frequencies and moderate, but rapidly tunable, spectral span. The output of a frequency-agile continuous-wave laser is split and sent into two electro-optic intensity modulators. Flat-top low-noise frequency combs are produced by wave-breaking in a nonlinear optical fibre of normal dispersion. With a dual-comb spectrometer, we record Doppler-limited spectra spanning 60 GHz within 13 μs and an 80 kHz refresh rate, at a tuning speed of 10 nm s-1. The sensitivity for weak absorption is enhanced by a long gas-filled hollow-core fibre. New opportunities for real-time diagnostics may be opened up, even outside the laboratory.

  6. Sandia Agile MEMS Prototyping, Layout Tools, Education and Services Program

    SciTech Connect

    Schriner, H.; Davies, B.; Sniegowski, J.; Rodgers, M.S.; Allen, J.; Shepard, C.

    1998-05-01

    Research and development in the design and manufacture of Microelectromechanical Systems (MEMS) is growing at an enormous rate. Advances in MEMS design tools and fabrication processes at Sandia National Laboratories` Microelectronics Development Laboratory (MDL) have broadened the scope of MEMS applications that can be designed and manufactured for both military and commercial use. As improvements in micromachining fabrication technologies continue to be made, MEMS designs can become more complex, thus opening the door to an even broader set of MEMS applications. In an effort to further research and development in MEMS design, fabrication, and application, Sandia National Laboratories has launched the Sandia Agile MEMS Prototyping, Layout Tools, Education and Services Program or SAMPLES program. The SAMPLES program offers potential partners interested in MEMS the opportunity to prototype an idea and produce hardware that can be used to sell a concept. The SAMPLES program provides education and training on Sandia`s design tools, analysis tools and fabrication process. New designers can participate in the SAMPLES program and design MEMS devices using Sandia`s design and analysis tools. As part of the SAMPLES program, participants` designs are fabricated using Sandia`s 4 level polycrystalline silicon surface micromachine technology fabrication process known as SUMMiT (Sandia Ultra-planar, Multi-level MEMS Technology). Furthermore, SAMPLES participants can also opt to obtain state of the art, post-fabrication services provided at Sandia such as release, packaging, reliability characterization, and failure analysis. This paper discusses the components of the SAMPLES program.

  7. The AGILE Alert System for Gamma-Ray Transients

    NASA Astrophysics Data System (ADS)

    Bulgarelli, A.; Trifoglio, M.; Gianotti, F.; Tavani, M.; Parmiggiani, N.; Fioretti, V.; Chen, A. W.; Vercellone, S.; Pittori, C.; Verrecchia, F.; Lucarelli, F.; Santolamazza, P.; Fanari, G.; Giommi, P.; Beneventano, D.; Argan, A.; Trois, A.; Scalise, E.; Longo, F.; Pellizzoni, A.; Pucella, G.; Colafrancesco, S.; Conforti, V.; Tempesta, P.; Cerone, M.; Sabatini, P.; Annoni, G.; Valentini, G.; Salotti, L.

    2014-01-01

    In recent years, a new generation of space missions has offered great opportunities for discovery in high-energy astrophysics. In this article we focus on the scientific operations of the Gamma-Ray Imaging Detector (GRID) on board the AGILE space mission. AGILE-GRID, sensitive in the energy range of 30 MeV-30 GeV, has detected many γ-ray transients of both galactic and extragalactic origin. This work presents the AGILE innovative approach to fast γ-ray transient detection, which is a challenging task and a crucial part of the AGILE scientific program. The goals are to describe (1) the AGILE Gamma-Ray Alert System, (2) a new algorithm for blind search identification of transients within a short processing time, (3) the AGILE procedure for γ-ray transient alert management, and (4) the likelihood of ratio tests that are necessary to evaluate the post-trial statistical significance of the results. Special algorithms and an optimized sequence of tasks are necessary to reach our goal. Data are automatically analyzed at every orbital downlink by an alert pipeline operating on different timescales. As proper flux thresholds are exceeded, alerts are automatically generated and sent as SMS messages to cellular telephones, via e-mail, and via push notifications from an application for smartphones and tablets. These alerts are crosschecked with the results of two pipelines, and a manual analysis is performed. Being a small scientific-class mission, AGILE is characterized by optimization of both scientific analysis and ground-segment resources. The system is capable of generating alerts within two to three hours of a data downlink, an unprecedented reaction time in γ-ray astrophysics.

  8. The agile alert system for gamma-ray transients

    SciTech Connect

    Bulgarelli, A.; Trifoglio, M.; Gianotti, F.; Fioretti, V.; Chen, A. W.; Pittori, C.; Verrecchia, F.; Lucarelli, F.; Santolamazza, P.; Fanari, G.; Giommi, P.; Pellizzoni, A.; and others

    2014-01-20

    In recent years, a new generation of space missions has offered great opportunities for discovery in high-energy astrophysics. In this article we focus on the scientific operations of the Gamma-Ray Imaging Detector (GRID) on board the AGILE space mission. AGILE-GRID, sensitive in the energy range of 30 MeV-30 GeV, has detected many γ-ray transients of both galactic and extragalactic origin. This work presents the AGILE innovative approach to fast γ-ray transient detection, which is a challenging task and a crucial part of the AGILE scientific program. The goals are to describe (1) the AGILE Gamma-Ray Alert System, (2) a new algorithm for blind search identification of transients within a short processing time, (3) the AGILE procedure for γ-ray transient alert management, and (4) the likelihood of ratio tests that are necessary to evaluate the post-trial statistical significance of the results. Special algorithms and an optimized sequence of tasks are necessary to reach our goal. Data are automatically analyzed at every orbital downlink by an alert pipeline operating on different timescales. As proper flux thresholds are exceeded, alerts are automatically generated and sent as SMS messages to cellular telephones, via e-mail, and via push notifications from an application for smartphones and tablets. These alerts are crosschecked with the results of two pipelines, and a manual analysis is performed. Being a small scientific-class mission, AGILE is characterized by optimization of both scientific analysis and ground-segment resources. The system is capable of generating alerts within two to three hours of a data downlink, an unprecedented reaction time in γ-ray astrophysics.

  9. Exercise-Based Fall Prevention in the Elderly: What About Agility?

    PubMed

    Donath, Lars; van Dieën, Jaap; Faude, Oliver

    2016-02-01

    Annually, one in three seniors aged over 65 years fall. Balance and strength training can reduce neuromuscular fall risk factors and fall rates. Besides conventional balance and strength training, explosive or high-velocity strength training, eccentric exercises, perturbation-based balance training, trunk strength, and trunk control have also been emphasized. In contrast, aerobic exercise has to date not been included in fall-prevention studies. However, well-developed endurance capacity might attenuate fatigue-induced declines in postural control in sports-related or general activities of daily living. Physical performance indices, such as balance, strength, and endurance, are generally addressed independently in exercise guidelines. This approach seems time consuming and may impede integrative training of sensorimotor, neuromuscular, and cardiocirculatory functions required to deal with balance-threatening situations in the elderly. An agility-based conceptual training framework comprising perception and decision making (e.g., visual scanning, pattern recognition, anticipation) and changes of direction (e.g., sudden starts, stops and turns; reactive control; concentric and eccentric contractions) might enable an integrative neuromuscular, cardiocirculatory, and cognitive training. The present paper aims to provide a scientific sketch of how to build such an integrated modular training approach, allowing adaptation of intensity, complexity, and cognitive challenge of the agility tasks to the participant's capacity. Subsequent research should address the (1) link between agility and fall risk factors as well as fall rates, (2) benefit-risk ratios of the proposed approach, (3) psychosocial aspects of agility training (e.g., motivation), and (4) logistical requirements (e.g., equipment needed). PMID:26395115

  10. Model and method for systems development

    NASA Astrophysics Data System (ADS)

    Behl, Erich; Rittel, Michael

    1988-11-01

    A method for systems development was developed with a view to the increase of productivity and quality. The basic approaches are a standard consideration of software and hardware and the rapid prototyping procedure. The methodological procedure is strongly characterized by the reuse of available concepts as well as of hardware and software components. The method is supported by a systems development environment which contains adjusted aids and automates a serres of activities.

  11. X-36 Tailless Fighter Agility Research Aircraft arrival at Dryden

    NASA Technical Reports Server (NTRS)

    1996-01-01

    NASA and McDonnell Douglas Corporation (MDC) personnel remove protective covers from the newly arrived NASA/McDonnell Douglas Corporation X-36 Tailless Fighter Agility Research Aircraft. It arrived at NASA Dryden Flight Research Center, Edwards, California, on July 2, 1996. The NASA/Boeing X-36 Tailless Fighter Agility Research Aircraft program successfully demonstrated the tailless fighter design using advanced technologies to improve the maneuverability and survivability of possible future fighter aircraft. The program met or exceeded all project goals. For 31 flights during 1997 at the Dryden Flight Research Center, Edwards, California, the project team examined the aircraft's agility at low speed / high angles of attack and at high speed / low angles of attack. The aircraft's speed envelope reached up to 206 knots (234 mph). This aircraft was very stable and maneuverable. It handled very well. The X-36 vehicle was designed to fly without the traditional tail surfaces common on most aircraft. Instead, a canard forward of the wing was used as well as split ailerons and an advanced thrust-vectoring nozzle for directional control. The X-36 was unstable in both pitch and yaw axes, so an advanced, single-channel digital fly-by-wire control system (developed with some commercially available components) was put in place to stabilize the aircraft. Using a video camera mounted in the nose of the aircraft and an onboard microphone, the X-36 was remotely controlled by a pilot in a ground station virtual cockpit. A standard fighter-type head-up display (HUD) and a moving-map representation of the vehicle's position within the range in which it flew provided excellent situational awareness for the pilot. This pilot-in-the-loop approach eliminated the need for expensive and complex autonomous flight control systems and the risks associated with their inability to deal with unknown or unforeseen phenomena in flight. Fully fueled the X-36 prototype weighed approximately 1

  12. Wavelength-Agile Optical Sensor for Exhaust Plume and Cryogenic Fluid Interrogation

    NASA Technical Reports Server (NTRS)

    Sanders, Scott T.; Chiaverini, Martin J.; Gramer, Daniel J.

    2004-01-01

    Two optical sensors developed in UW-Madison labs were evaluated for their potential to characterize rocket engine exhaust plumes and liquid oxygen (LOX) fluid properties. The plume sensor is based on wavelength-agile absorption spectroscopy A device called a chirped white pulse emitter (CWPE) is used to generate the wavelength agile light, scanning, for example, 1340 - 1560 nm every microsecond. Properties of the gases in the rocket plume (for example temperature and water mole fraction) can be monitored using these wavelength scans. We have performed preliminary tests in static gas cells, a laboratory GOX/GH2 thrust chamber, and a solid-fuel hybrid thrust chamber, and these initial tests demonstrate the potential of the CWPE for monitoring rocket plumes. The LOX sensor uses an alternative to wavelength agile sensing: two independent, fixed-wavelength lasers are combined into a single fiber. One laser is absorbed by LOX and the other not: by monitoring the differential transmission the LOX concentration in cryogenic feed lines can be inferred. The sensor was successful in interrogating static LOX pools in laboratory tests. Even in ice- and bubble-laden cryogenic fluids, LOX concentrations were measured to better than 1% with a 3 microsec time constant.

  13. Cytochrome P450 loss-of-function polymorphism genotyping on the Agilent Bioanalyzer and clinical application.

    PubMed

    Piatkov, Irina; Jones, Trudi; Rochester, Colin

    2009-12-01

    Responses to toxins and drugs, even to standard medical drug treatment regimens, can vary significantly between individuals. Similar dosages can have divergent results due to polymorphisms in the genes that code for the enzymes responsible for the metabolism of drugs. The focus of this report is to describe our exploration of the personalized medicine approach for patient care at Sydney West Area Health Service. We would like to demonstrate the importance of this approach as it is the subject of debate in the medical and scientific community. The critical points in this debate are the cost of testing, laboratory space required and clinical application. We have shown that a simple approach and instruments like the Agilent Bioanalyzer could be cost effective for laboratory operation. The Agilent Bioanalyzer (Agilent Technologies, CA, USA) can be used for proteins, DNA and cell studies. Hence, reduced cost of instruments, laboratory space requirements, maintenance and operational costs are great advantages of this technology, especially for development and research laboratories. PMID:19958097

  14. Development of Methods for Determination of Aflatoxins.

    PubMed

    Xie, Lijuan; Chen, Min; Ying, Yibin

    2016-12-01

    Aflatoxins can cause damage to the health of humans and animals. Several institutions around the world have established regulations to limit the levels of aflatoxins in food, and numerous analytical methods have been extensively developed for aflatoxin determination. This review covers the currently used analytical methods for the determination of aflatoxins in different food matrices, which includes sampling and sample preparation, sample pretreatment methods including extraction methods and purification methods of aflatoxin extracts, separation and determination methods. Validation for analysis of aflatoxins and safety considerations and precautions when doing the experiments are also discussed. PMID:25840003

  15. The Frequency Agile Solar Radiotelescope (FASR)

    NASA Astrophysics Data System (ADS)

    White, S. M.; Gary, D. E.; Bastian, T. S.; Hurford, G. J.; Lanzerotti, L. J.

    2003-04-01

    The Frequency Agile Solar Radiotelescope (FASR) is a radio interferometer designed to make high spatial resolution images of the Sun across a broad range of radio wavelengths simultaneously, allowing the technique of imaging spectroscopy to be exploited on a routine basis. The telescope will cover the frequency range 0.1-30 GHz using several sets of receiving elements that provide full-disk imaging, with of order 100 antennas at highest frequency range. FASR will be optimized for solar radio phenomena and will be the most powerful and versatile radioheliograph ever built, providing an improvement of orders of magnitude in image quality over existing instruments. FASR recently received the top ranking amongst all small projects considered by the decadal survey of the National Academy of Science Committee on Solar and Space Physics. FASR will probe all phenomena in the solar atmosphere from the mid-chromosphere outwards. In particular, FASR will provide direct measurement of coronal magnetic field strengths, will image the nonthermal solar atmosphere and show directly the locations of electrons accelerated by solar flares, will provide images of coronal mass ejections travelling outwwards through the solar corona, and supply extensive data products for forecasting and synoptic studies. A major emphasis in the project is to make FASR data as widely and easily used as possible, i.e., providing the general user with processed, fully-calibrated high-quality images that do not need particular knowledge of radio astronomy for interpretation. This paper will describe the telescope and its science goals, and summarize its current status.

  16. a Photon Tag Calibration Beam for the Agile Satellite

    NASA Astrophysics Data System (ADS)

    Hasan, S.; Prest, M.; Foggetta, L.; Pontoni, C.; Mozzanica, A.; Barbiellini, G.; Basset, M.; Liello, F.; Longo, F.; Vallazza, E.; Buonomo, G.; Mazzitelli, G.; Quintieri, L.; Valente, P.; Boffelli, F.; Cattaneo, P.; Mauri, F.

    2006-04-01

    The AGILE satellite will be launched in 2006 for the study of gamma rays in the energy range 30 MeV-50 GeV. The satellite has to be calibrated using gamma rays of known energy. The calibration facility is being developed at the Beam Test Facility (BTF) at the INFN Laboratories in Frascati. The photons are produced by bremsstrahlung of electrons with a maximum momentum of 750 MeV/c. The electrons are tagged using a dipole magnet whose internal walls are covered by microstrip silicon detectors: depending on the energy loss, they impinge on a different strip once the dipole current has been set to a given value. The correlation between the direction of the electron measured by a pair of x-y silicon chambers and the impinging position on the tagging module inside the magnet allows the tagging of the photon. The paper describes the calibration layout and tests and the results, compared with the Montecarlo simulation, in terms of production rate and energy resolution.

  17. SBIR Grant:No-Vibration Agile Cryogenic Optical Refrigerator

    SciTech Connect

    Epstein, Richard

    2013-04-09

    Optical refrigeration is currently the only all-solid-state cryocooling technology that has been demonstrated. Optical cryocoolers are devices that use laser light to cool small crystal or glass cooling elements. The cooling element absorbs the laser light and reradiates it at higher energy, an example of anti-Stokes fluorescence. The dif-ference between the energy of the outgoing and incoming light comes from the thermal energy of the cooling element, which in turn becomes colder. Entitled No-Vibration Agile Cryocoolers using Optical Refrigeration, this Phase I proposal directly addressed the continued development of the optical refrigerator components necessary to transition this scientific breakthrough into National Nu-clear Security Administration (NNSA) sensor applications in line with the objectives of topic 50b. ThermoDynamic Films LLC (TDF), in collaboration with the University of New Mexico (UNM), cooled an optical-refrigerator cooling element comprised of an ytterbium-doped yttrium lithium fluoride (Yb:YLF) crystal from room tempera-ture to 123 K with about 2% efficiency. This is the world record in optical refrigera-tion and an important step toward revolutionizing cryogenic systems for sensor ap-plications. During this period, they also designed and analyzed the crucial elements of a prototype optical refrigerator including the thermal link that connects the cool-ing element with the load.

  18. Function-based integration strategy for an agile manufacturing testbed

    NASA Astrophysics Data System (ADS)

    Park, Hisup

    1997-01-01

    This paper describes an integration strategy for plug-and- play software based on functional descriptions of the software modules. The functional descriptions identify explicitly the role of each module with respect to the overall systems. They define the critical dependencies that affect the individual modules and thus affect the behavior of the system. The specified roles, dependencies and behavioral constraints are then incorporated in a group of shared objects that are distributed over a network. These objects may be interchanged with others without disrupting the system so long as the replacements meet the interface and functional requirements. In this paper, we propose a framework for modeling the behavior of plug-and-play software modules that will be used to (1) design and predict the outcome of the integration, (2) generate the interface and functional requirements of individual modules, and (3) form a dynamic foundation for applying interchangeable software modules. I describe this strategy in the context of the development of an agile manufacturing testbed. The testbed represents a collection of production cells for machining operations, supported by a network of software modules or agents for planning, fabrication, and inspection. A process definition layer holds the functional description of the software modules. A network of distributed objects interact with one another over the Internet and comprise the plug-compatible software nodes that execute these functions. This paper will explore the technical and operational ramifications of using the functional description framework to organize and coordinate the distributed object modules.

  19. A framework for teaching software development methods

    NASA Astrophysics Data System (ADS)

    Dubinsky, Yael; Hazzan, Orit

    2005-12-01

    This article presents a study that aims at constructing a teaching framework for software development methods in higher education. The research field is a capstone project-based course, offered by the Technion's Department of Computer Science, in which Extreme Programming is introduced. The research paradigm is an Action Research that involves cycles of data collection, examination, evaluation, and application of results. The research uses several research tools for data gathering, as well as several research methods for data interpretation. The article describes in detail the research background, the research method, and the gradual emergence process of a framework for teaching software development methods. As part of the comprehensive teaching framework, a set of measures is developed to assess, monitor, and improve the teaching and the actual process of software development projects.

  20. PM MASS METHODS RESEARCH AND DEVELOPMENT

    EPA Science Inventory

    This task supports research into methodologies for determining particulate matter (PM) mass concentrations. Due to the complexity of PM (composition, size distribution, and concentration), developing PM methods that perform acceptably under most weather conditions at most U.S. l...

  1. Pathways to agility in the production of neutron generators

    SciTech Connect

    Stoltz, R.E.; Beavis, L.C.; Cutchen, J.T.; Garcia, P.; Gurule, G.A.; Harris, R.N.; McKey, P.C.; Williams, D.W.

    1994-02-01

    This report is the result of a study team commissioned to explore pathways for increased agility in the manufacture of neutron generators. As a part of Sandia`s new responsibility for generator production, the goal of the study was to identify opportunities to reduce costs and increase flexibility in the manufacturing operation. Four parallel approaches (or pathways) were recommended: (1) Know the goal, (2) Use design leverage effectively, (3) Value simplicity, and (4) Configure for flexibility. Agility in neutron generator production can be enhanced if all of these pathways are followed. The key role of the workforce in achieving agility was also noted, with emphasis on ownership, continuous learning, and a supportive environment.

  2. Comparison of conventional and microlens-array agile beam steerers

    NASA Astrophysics Data System (ADS)

    McDearmon, Graham F.; Flood, Kevin M.; Finlan, J. Michael

    1995-05-01

    We analyzed the optical and mechanical performance of several designs of agile beam steerers based on refractive microlens arrays for sensing and imaging applications in the visible and infrared wavebands. Ray-trace analyses showed that the best design is capable of steering narrowband illumination +/- 25 degree(s) in two dimensions with nearly diffraction-limited performance. The maximum steering angle depends on the materials. We found that imaging the field of regard takes significantly more time than scanning it unless cameras with very high frame-rates are used. We performed many parametric studies that can be used to optimize the design for any application. We compared optimal designs for microlens-array and conventional galvanometric agile beam steerers. The microlens-array agile beam steerer provides significant improvements in scanning speed, random access pointing, energy consumption, mass reduction, and volume reduction.

  3. A study of a proposed modified torsional agility metric

    NASA Technical Reports Server (NTRS)

    Valasek, John; Eggold, David P.; Downing, David R.

    1991-01-01

    A new candidate lateral agility metric, the modified torsional agility parameter, is proposed and tested through generic, nonlinear, non-real-time flight simulation programs of the F-18 and F-5A. The metric is aimed at quantifying high subsonic loaded roll capabilities which might be useful in modern air combat. The metric is considered to be straightforward for testing and measuring based on nonreal-time unmanned flight simulation. The metric is found to be sensitive to pilot input errors of less than full lateral stick to capture bank angle, when tested using unmanned flight simulations. It is suggested that, for redesigned configurations of both aircraft with improved lateral agility, the major benefit would be provided by fast and highly effective rudders, and a high level of pitch, roll, and yaw damping at moderate to high normal load factor levels.

  4. Toxicity test method development in southeast Asia

    SciTech Connect

    McPherson, C.A.

    1995-12-31

    Use of aquatic toxicity tests is relatively new in southeast Asia. As part of the ASEAN-Canada Cooperative Programme on Marine Science -- Phase 2, which includes development of marine environmental criteria, a need for tropical toxicity data was identified. A step-wise approach was used for test method development (simple, acute tests and easily measured endpoints first, then more complex short-term chronic methods), for test specific selection (using species found throughout the region first, and then considering species with narrower geographic distribution), and for integration of quality assurance/quality control (QA/QC) practices into all laboratory activities. Development of test protocols specifically for tropical species included acute and chronic toxicity tests with marine fish, invertebrates and algae. Criteria for test species selection will be reviewed. Method development was based on procedures and endpoints already widely used in North America and Europe (e.g., 96-h LC50 with fish), but adapted for use with tropical species. For example, a bivalve larval development test can use the same endpoints but the duration is only 24 hours. Test method development included research on culture and holding procedures, determination of test conditions (e.g., duration, test containers), and identification of appropriate endpoints. Acute tests with fish and invertebrates were developed first. The next step was development of short-term chronic tests to measure phytoplankton growth, bivalve and echinoderm embryo or larval development, and larval fish growth. The number of species and types of tests was increased in a staged approach, as laboratories became better equipped and personnel gained practical experience. In most cases, method development coincided with training workshops to introduce the principles of toxicity testing.

  5. Biorobotics: using robots to emulate and investigate agile locomotion.

    PubMed

    Ijspeert, Auke J

    2014-10-10

    The graceful and agile movements of animals are difficult to analyze and emulate because locomotion is the result of a complex interplay of many components: the central and peripheral nervous systems, the musculoskeletal system, and the environment. The goals of biorobotics are to take inspiration from biological principles to design robots that match the agility of animals, and to use robots as scientific tools to investigate animal adaptive behavior. Used as physical models, biorobots contribute to hypothesis testing in fields such as hydrodynamics, biomechanics, neuroscience, and prosthetics. Their use may contribute to the design of prosthetic devices that more closely take human locomotion principles into account. PMID:25301621

  6. Development of test methods for textile composites

    NASA Technical Reports Server (NTRS)

    Masters, John E.; Ifju, Peter G.; Fedro, Mark J.

    1993-01-01

    NASA's Advanced Composite Technology (ACT) Program was initiated in 1990 with the purpose of developing less costly composite aircraft structures. A number of innovative materials and processes were evaluated as a part of this effort. Chief among them are composite materials reinforced with textile preforms. These new forms of composite materials bring with them potential testing problems. Methods currently in practice were developed over the years for composite materials made from prepreg tape or simple 2-D woven fabrics. A wide variety of 2-D and 3-D braided, woven, stitched, and knit preforms were suggested for application in the ACT program. The applicability of existing test methods to the wide range of emerging materials bears investigation. The overriding concern is that the values measured are accurate representations of the true material response. The ultimate objective of this work is to establish a set of test methods to evaluate the textile composites developed for the ACT Program.

  7. Methods for the Study of Gonadal Development.

    PubMed

    Piprek, Rafal P

    2016-01-01

    Current knowledge on gonadal development and sex determination is the product of many decades of research involving a variety of scientific methods from different biological disciplines such as histology, genetics, biochemistry, and molecular biology. The earliest embryological investigations, followed by the invention of microscopy and staining methods, were based on histological examinations. The most robust development of histological staining techniques occurred in the second half of the nineteenth century and resulted in structural descriptions of gonadogenesis. These first studies on gonadal development were conducted on domesticated animals; however, currently the mouse is the most extensively studied species. The next key point in the study of gonadogenesis was the advancement of methods allowing for the in vitro culture of fetal gonads. For instance, this led to the description of the origin of cell lines forming the gonads. Protein detection using antibodies and immunolabeling methods and the use of reporter genes were also invaluable for developmental studies, enabling the visualization of the formation of gonadal structure. Recently, genetic and molecular biology techniques, especially gene expression analysis, have revolutionized studies on gonadogenesis and have provided insight into the molecular mechanisms that govern this process. The successive invention of new methods is reflected in the progress of research on gonadal development. PMID:27300186

  8. Development and Validation of a Stability Indicating RP-UPLC Method for Determination of Quetiapine in Pharmaceutical Dosage Form

    PubMed Central

    Trivedi, Rakshit Kanubhai; Patel, Mukesh C.

    2011-01-01

    The present work reports a stability indicating reversed phase ultra performance liquid chromatography (RP-UPLC) method for the quantitative determination of quetiapine in pharmaceutical dosage form. The chromatographic separation is performed on an Agilent Eclipse Plus C18, RRHD 1.8 μm (50 mm x 2.1 mm) column using gradient elution. The optimized mobile phase consists of 0.1 % aqueous triethylamine (pH 7.2) as a solvent-A and 80:20 v/v mixture of acetonitrile and methanol as solvent-B. The eluted compounds are monitored at 252 nm wavelength using a UV detector. The developed method separates quetiapine from its five impurities/degradation products within a run time of 5 min. Stability indicating capability of the developed method is established by analyzing forced degradation samples in which the spectral purity of quetiapine is ascertained along with the separation of degradation products from analyte peak. The developed RP-UPLC method is validated as per International Conference on Harmonization (ICH) guidelines with respect to system suitability, specificity, precision, accuracy, linearity, robustness and filter compatibility. PMID:21617775

  9. The influence of agility training on physiological and cognitive performance.

    PubMed

    Lennemann, Lynette M; Sidrow, Kathryn M; Johnson, Erica M; Harrison, Catherine R; Vojta, Christopher N; Walker, Thomas B

    2013-12-01

    Agility training (AT) has recently been instituted in several military communities in hopes of improving combat performance and general fitness. The purpose of this study was to determine how substituting AT for traditional military physical training (PT) influences physical and cognitive performance. Forty-one subjects undergoing military technical training were divided randomly into 2 groups for 6 weeks of training. One group participated in standard military PT consisting of calisthenics and running. A second group duplicated the amount of exercise of the first group but used AT as their primary mode of training. Before and after training, subjects completed a physical and cognitive battery of tests including V[Combining Dot Above]O2max, reaction time, Illinois Agility Test, body composition, visual vigilance, dichotic listening, and working memory tests. There were significant improvements within the AT group in V[Combining Dot Above]O2max, Illinois Agility Test, visual vigilance, and continuous memory. There was a significant increase in time-to-exhaustion for the traditional group. We conclude that AT is as effective or more effective as PT in enhancing physical fitness. Further, it is potentially more effective than PT in enhancing specific measures of physical and cognitive performance, such as physical agility, memory, and vigilance. Consequently, we suggest that AT be incorporated into existing military PT programs as a way to improve war-fighter performance. Further, it seems likely that the benefits of AT observed here occur in various other populations. PMID:23442271

  10. Tailoring Agility: Promiscuous Pair Story Authoring and Value Calculation

    NASA Astrophysics Data System (ADS)

    Tendon, Steve

    This chapter describes how a multi-national software organization created a business plan involving business units from eight countries that followed an agile way, after two previously failed attempts with traditional approaches. The case is told by the consultant who initiated implementation of agility into requirements gathering, estimation and planning processes in an international setting. The agile approach was inspired by XP, but then tailored to meet the peculiar requirements. Two innovations were critical. The first innovation was promiscuous pair story authoring, where user stories were written by two people (similarly to pair programming), and the pairing changed very often (as frequently as every 15-20 minutes) to achieve promiscuity and cater for diverse point of views. The second innovation was an economic value evaluation (and not the cost) which was attributed to stories. Continuous recalculation of the financial value of the stories allowed to assess the projects financial return. In this case implementation of agility in the international context allowed the involved team members to reach consensus and unanimity of decisions, vision and purpose.

  11. Developing a Primary Science Methods Classroom

    ERIC Educational Resources Information Center

    Veal, William R.; Jackson, Zachary

    2006-01-01

    The purpose of this paper is to describe how and why a primary science methods classroom was conceived, designed, and developed for preservice and inservice teachers. Just as science educators believe that students learn best by constructing their knowledge of the natural world with the aid of a teacher and colleagues, science educators also…

  12. New Developments of the Shared Concern Method.

    ERIC Educational Resources Information Center

    Pikas, Anatol

    2002-01-01

    Reviews and describes new developments in the Shared Concern method (SCm), a tool for tackling group bullying amongst teenagers by individual talks. The psychological mechanisms of healing in the bully group and what hinders the bully therapist in eliciting them have become better clarified. The most important recent advancement of the SCm…

  13. A Framework for Teaching Software Development Methods

    ERIC Educational Resources Information Center

    Dubinsky, Yael; Hazzan, Orit

    2005-01-01

    This article presents a study that aims at constructing a teaching framework for software development methods in higher education. The research field is a capstone project-based course, offered by the Technion's Department of Computer Science, in which Extreme Programming is introduced. The research paradigm is an Action Research that involves…

  14. Benchmarking Learning and Teaching: Developing a Method

    ERIC Educational Resources Information Center

    Henderson-Smart, Cheryl; Winning, Tracey; Gerzina, Tania; King, Shalinie; Hyde, Sarah

    2006-01-01

    Purpose: To develop a method for benchmarking teaching and learning in response to an institutional need to validate a new program in Dentistry at the University of Sydney, Australia. Design/methodology/approach: After a collaborative partner, University of Adelaide, was identified, the areas of teaching and learning to be benchmarked, PBL…

  15. Study on spectrally agile staring sensor using acousto-optic tunable filter

    NASA Astrophysics Data System (ADS)

    Cui, Yan; Zhang, Minghui

    1992-08-01

    The spectrally agile staring sensor (SASS) is an instrument system that is able to get image and spectrum information. This paper analyzes the expression of signal-to-noise ratio and overall performance of the SASS system that uses an acousto-optic tunable filter as its spectral filter, and points out improving methods and limiting factors of the system performance. The complete SASS system experimental set-up is constructed. Using this set-up, the theory is verified, and the image and spectrum information of the simulated target is acquired.

  16. Development of semiclassical molecular dynamics simulation method.

    PubMed

    Nakamura, Hiroki; Nanbu, Shinkoh; Teranishi, Yoshiaki; Ohta, Ayumi

    2016-04-28

    Various quantum mechanical effects such as nonadiabatic transitions, quantum mechanical tunneling and coherence play crucial roles in a variety of chemical and biological systems. In this paper, we propose a method to incorporate tunneling effects into the molecular dynamics (MD) method, which is purely based on classical mechanics. Caustics, which define the boundary between classically allowed and forbidden regions, are detected along classical trajectories and the optimal tunneling path with minimum action is determined by starting from each appropriate caustic. The real phase associated with tunneling can also be estimated. Numerical demonstration with use of a simple collinear chemical reaction O + HCl → OH + Cl is presented in order to help the reader to well comprehend the method proposed here. Generalization to the on-the-fly ab initio version is rather straightforward. By treating the nonadiabatic transitions at conical intersections by the Zhu-Nakamura theory, new semiclassical MD methods can be developed. PMID:27067383

  17. Development of a nonlinear vortex method

    NASA Technical Reports Server (NTRS)

    Kandil, O. A.

    1982-01-01

    Steady and unsteady Nonliner Hybrid Vortex (NHV) method, for low aspect ratio wings at large angles of attack, is developed. The method uses vortex panels with first-order vorticity distribution (equivalent to second-order doublet distribution) to calculate the induced velocity in the near field using closed form expressions. In the far field, the distributed vorticity is reduced to concentrated vortex lines and the simpler Biot-Savart's law is employed. The method is applied to rectangular wings in steady and unsteady flows without any restriction on the order of magnitude of the disturbances in the flow field. The numerical results show that the method accurately predicts the distributed aerodynamic loads and that it is of acceptable computational efficiency.

  18. High alpha feedback control for agile half-loop maneuvers of the F-18 airplane

    NASA Technical Reports Server (NTRS)

    Stalford, Harold

    1988-01-01

    A nonlinear feedback control law for the F/A-18 airplane that provides time-optimal or agile maneuvering of the half-loop maneuver at high angles of attack is given. The feedback control law was developed using the mathematical approach of singular perturbations, in which the control devices considered were conventional aerodynamic control surfaces and thrusting. The derived nonlinear control law was used to simulate F/A-18 half-loop maneuvers. The simulated results at Mach 0.6 and 0.9 compared well with pilot simulations conducted at NASA.

  19. Agile beam laser radar using computational imaging for robotic perception

    NASA Astrophysics Data System (ADS)

    Powers, Michael A.; Stann, Barry L.; Giza, Mark M.

    2015-05-01

    This paper introduces a new concept that applies computational imaging techniques to laser radar for robotic perception. We observe that nearly all contemporary laser radars for robotic (i.e., autonomous) applications use pixel basis scanning where there is a one-to-one correspondence between world coordinates and the measurements directly produced by the instrument. In such systems this is accomplished through beam scanning and/or the imaging properties of focal-plane optics. While these pixel-basis measurements yield point clouds suitable for straightforward human interpretation, the purpose of robotic perception is the extraction of meaningful features from a scene, making human interpretability and its attendant constraints mostly unnecessary. The imposing size, weight, power and cost of contemporary systems is problematic, and relief from factors that increase these metrics is important to the practicality of robotic systems. We present a system concept free from pixel basis sampling constraints that promotes efficient and adaptable sensing modes. The cornerstone of our approach is agile and arbitrary beam formation that, when combined with a generalized mathematical framework for imaging, is suited to the particular challenges and opportunities of robotic perception systems. Our hardware concept looks toward future systems with optical device technology closely resembling modern electronically-scanned-array radar that may be years away from practicality. We present the design concept and results from a prototype system constructed and tested in a laboratory environment using a combination of developed hardware and surrogate devices for beam formation. The technological status and prognosis for key components in the system is discussed.

  20. Development and validation of a stability-indicating HPLC method for determination of voriconazole and its related substances.

    PubMed

    Gu, Ping; Li, Yuru

    2009-08-01

    An isocratic reversed-phase high performance liquid chromatographic (RP-HPLC) method has been developed and validated for the determination of voriconazole and its related substances. The drug substance was subjected to stress conditions of UV light, water hydrolysis, acid, base, oxidation, and deoxidization to observe the degradation products. The successful separation of voriconazole from its synthetic impurities and degradation products formed under stress conditions was achieved using an Agilent Zorbax SB-C18 (250mm x 4.6 mm i.d., 5 microm) column maintained at 25 degrees C with a mobile phase of a mixture of ammonium phosphate dibasic buffer (pH adjusted to 6.0 using diluted orthophosphoric acid; 50 mM)-acetonitrile (52:48, v/v). The mobile phase flow rate was 1.0 mL/min, and the detection wavelength was 250 nm. The stress sample solutions were assayed against the qualified reference standard of voriconazole and the mass balance in each case was close to 99.7%, confirming its stability-indication capacity. The developed HPLC method was validated with respect to linearity, accuracy, precision, specificity, and robustness. The developed HPLC method to determine the related substances and assay determination of voriconazole can be used to evaluate the quality of regular production samples. It can be also used to test the stability samples of voriconazole. PMID:19772734

  1. X-36 Tailless Fighter Agility Research Aircraft in flight

    NASA Technical Reports Server (NTRS)

    1997-01-01

    The tailless X-36 technology demonstrator research aircraft cruises over the California desert at low altitude during a 1997 research flight. The NASA/Boeing X-36 Tailless Fighter Agility Research Aircraft program successfully demonstrated the tailless fighter design using advanced technologies to improve the maneuverability and survivability of possible future fighter aircraft. The program met or exceeded all project goals. For 31 flights during 1997 at the Dryden Flight Research Center, Edwards, California, the project team examined the aircraft's agility at low speed / high angles of attack and at high speed / low angles of attack. The aircraft's speed envelope reached up to 206 knots (234 mph). This aircraft was very stable and maneuverable. It handled very well. The X-36 vehicle was designed to fly without the traditional tail surfaces common on most aircraft. Instead, a canard forward of the wing was used as well as split ailerons and an advanced thrust-vectoring nozzle for directional control. The X-36 was unstable in both pitch and yaw axes, so an advanced, single-channel digital fly-by-wire control system (developed with some commercially available components) was put in place to stabilize the aircraft. Using a video camera mounted in the nose of the aircraft and an onboard microphone, the X-36 was remotely controlled by a pilot in a ground station virtual cockpit. A standard fighter-type head-up display (HUD) and a moving-map representation of the vehicle's position within the range in which it flew provided excellent situational awareness for the pilot. This pilot-in-the-loop approach eliminated the need for expensive and complex autonomous flight control systems and the risks associated with their inability to deal with unknown or unforeseen phenomena in flight. Fully fueled the X-36 prototype weighed approximately 1,250 pounds. It was 19 feet long and three feet high with a wingspan of just over 10 feet. A Williams International F112 turbofan engine

  2. X-36 Tailless Fighter Agility Research Aircraft in flight

    NASA Technical Reports Server (NTRS)

    1997-01-01

    The X-36 technology demonstrator shows off its distinctive shape as the remotely piloted aircraft flies a research mission over the Southern California desert on October 30, 1997. The NASA/Boeing X-36 Tailless Fighter Agility Research Aircraft program successfully demonstrated the tailless fighter design using advanced technologies to improve the maneuverability and survivability of possible future fighter aircraft. The program met or exceeded all project goals. For 31 flights during 1997 at the Dryden Flight Research Center, Edwards, California, the project team examined the aircraft's agility at low speed / high angles of attack and at high speed / low angles of attack. The aircraft's speed envelope reached up to 206 knots (234 mph). This aircraft was very stable and maneuverable. It handled very well. The X-36 vehicle was designed to fly without the traditional tail surfaces common on most aircraft. Instead, a canard forward of the wing was used as well as split ailerons and an advanced thrust-vectoring nozzle for directional control. The X-36 was unstable in both pitch and yaw axes, so an advanced, single-channel digital fly-by-wire control system (developed with some commercially available components) was put in place to stabilize the aircraft. Using a video camera mounted in the nose of the aircraft and an onboard microphone, the X-36 was remotely controlled by a pilot in a ground station virtual cockpit. A standard fighter-type head-up display (HUD) and a moving-map representation of the vehicle's position within the range in which it flew provided excellent situational awareness for the pilot. This pilot-in-the-loop approach eliminated the need for expensive and complex autonomous flight control systems and the risks associated with their inability to deal with unknown or unforeseen phenomena in flight. Fully fueled the X-36 prototype weighed approximately 1,250 pounds. It was 19 feet long and three feet high with a wingspan of just over 10 feet. A Williams

  3. X-36 Tailless Fighter Agility Research Aircraft in flight

    NASA Technical Reports Server (NTRS)

    1997-01-01

    The lack of a vertical tail on the X-36 technology demonstrator is evident as the remotely piloted aircraft flies a low-altitude research flight above Rogers Dry Lake at Edwards Air Force Base in the California desert on October 30, 1997. The NASA/Boeing X-36 Tailless Fighter Agility Research Aircraft program successfully demonstrated the tailless fighter design using advanced technologies to improve the maneuverability and survivability of possible future fighter aircraft. The program met or exceeded all project goals. For 31 flights during 1997 at the Dryden Flight Research Center, Edwards, California, the project team examined the aircraft's agility at low speed / high angles of attack and at high speed / low angles of attack. The aircraft's speed envelope reached up to 206 knots (234 mph). This aircraft was very stable and maneuverable. It handled very well. The X-36 vehicle was designed to fly without the traditional tail surfaces common on most aircraft. Instead, a canard forward of the wing was used as well as split ailerons and an advanced thrust-vectoring nozzle for directional control. The X-36 was unstable in both pitch and yaw axes, so an advanced, single-channel digital fly-by-wire control system (developed with some commercially available components) was put in place to stabilize the aircraft. Using a video camera mounted in the nose of the aircraft and an onboard microphone, the X-36 was remotely controlled by a pilot in a ground station virtual cockpit. A standard fighter-type head-up display (HUD) and a moving-map representation of the vehicle's position within the range in which it flew provided excellent situational awareness for the pilot. This pilot-in-the-loop approach eliminated the need for expensive and complex autonomous flight control systems and the risks associated with their inability to deal with unknown or unforeseen phenomena in flight. Fully fueled the X-36 prototype weighed approximately 1,250 pounds. It was 19 feet long and three

  4. Transport Test Problems for Hybrid Methods Development

    SciTech Connect

    Shaver, Mark W.; Miller, Erin A.; Wittman, Richard S.; McDonald, Benjamin S.

    2011-12-28

    This report presents 9 test problems to guide testing and development of hybrid calculations for the ADVANTG code at ORNL. These test cases can be used for comparing different types of radiation transport calculations, as well as for guiding the development of variance reduction methods. Cases are drawn primarily from existing or previous calculations with a preference for cases which include experimental data, or otherwise have results with a high level of confidence, are non-sensitive, and represent problem sets of interest to NA-22.

  5. Development of a hydraulic turbine design method

    NASA Astrophysics Data System (ADS)

    Kassanos, Ioannis; Anagnostopoulos, John; Papantonis, Dimitris

    2013-10-01

    In this paper a hydraulic turbine parametric design method is presented which is based on the combination of traditional methods and parametric surface modeling techniques. The blade of the turbine runner is described using Bezier surfaces for the definition of the meridional plane as well as the blade angle distribution, and a thickness distribution applied normal to the mean blade surface. In this way, it is possible to define parametrically the whole runner using a relatively small number of design parameters, compared to conventional methods. The above definition is then combined with a commercial CFD software and a stochastic optimization algorithm towards the development of an automated design optimization procedure. The process is demonstrated with the design of a Francis turbine runner.

  6. The Dilemma of High Level Planning in Distributed Agile Software Projects: An Action Research Study in a Danish Bank

    NASA Astrophysics Data System (ADS)

    Svejvig, Per; Fladkjær Nielsen, Ann-Dorte

    The chapter reports on an action research study with the aim to design a high level planning process in distributed and co-located software projects based on agile methods. The main contributions are the insight that high level planning process is highly integrated with other project disciplines and specific steps has to be taken to apply the process in distributed projects; and the action research approach is indeed suitable to software process improvements.

  7. Report on development of neutron passportisation method

    SciTech Connect

    Antropov, G.P.; Babichev, Yu.B.; Blagin, S.V.

    1994-12-31

    In this report the results of development of spatial neutron passportisation method are described. The method is aimed on spatial configuration (including the number of sources) control of closed objects containing neutron sources. The possible areas of method application are: (1) the number of warheads control inside the missile heads for RF-US nuclear disarmament treaties verification; (2) control of SNM containers arrangement in storage vaults; (3) control of complicated assemblies with SNM (and other radioactive materials) to remain unchanged. For objects with complicated structure such as multiple reentry vehicles the direct interpretation of observed radiation field configuration is rather difficult task. The reconstruction of object structure on basis of radiation field configuration usually require use of external information and is often not obvious. Besides, while using such methods of direct reconstruction of object internal structure the contradiction arises between the requirement of defining sources arrangement (warheads in case of arms control) and requirement of information protection concerning the sources themselves. In this case there may be different limitations on possible spatial resolution of method, use of spectroscopy information, etc.

  8. CHARACTERIZATION, HPLC METHOD DEVELOPMENT AND IMPURITY IDENTIFICATION FOR 3,4,3-LI(1,2-HOPO), A POTENT ACTINIDE CHELATOR FOR RADIONUCLIDE DECORPORATION

    PubMed Central

    Liu, Mingtao; Wang, Jennie; Wu, Xiaogang; Wang, Euphemia; Abergel, Rebecca J.; Shuh, David K.; Raymond, Kenneth N.; Liu, Paul

    2014-01-01

    3,4,3-LI(1,2-HOPO), 1,5,10,14-tetra(1-hydroxy-2-pyridon-6-oyl)-1,5,10,14-tetraazatetradecane), is a potent octadentate chelator of actinides. It is being developed as a decorporation treatment for internal contamination with radionuclides. Conventional HPLC methods exhibited speciation peaks and bridging, likely attributable to the agent’s complexation with residual metallic ions in the HPLC system. Derivatization of the target ligand in situ with Fe(III) chloride, however, provided a single homogeneous iron-complex that can readily be detected and analyzed by HPLC. The HPLC method used an Agilent Eclipse XDB-C18 column (150 mm × 4.6 mm, 5 μm) at 25 °C with UV detection at 280 nm. A gradient elution, with acetonitrile (11% to 100%)/buffer mobile phase, was developed for impurity profiling. The buffer consisted of 0.02% formic acid and 10 mM ammonium formate at pH 4.6. An Agilent 1200 LC-6530 Q-TOF/MS system was employed to characterize the [Fe(III)-3,4,3-LI(1,2-HOPO)] derivative and impurities. The proposed HPLC method was validated for specificity, linearity (concentration range 0.13–0.35 mg/mL, r = 0.9999), accuracy (recovery 98.3–103.3%), precision (RSD ≤ 1.6%) and sensitivity (LOD 0.08 μg/mL). The LC/HRMS revealed that the derivative was a complex consisting of one 3,4,3-LI(1,2-HOPO) molecule, one hydroxide ligand, and two iron atoms. Impurities were also identified with LC/HRMS. The validated HPLC method was used in shelf-life evaluation studies which showed that the API remained unchanged for one year at 25°C/60% RH. PMID:25459944

  9. Data transfer through beam steering using agile lensing

    NASA Astrophysics Data System (ADS)

    Arshad, Muhammad Assad; Reza, Syed Azer; Muhammad, Ahsan

    2016-04-01

    This paper presents a data transfer scheme using multi-focus tunable lenses. The design involves the use of a standard laser source and a variable focus agile lens to steer to the laser beam that passes through the lens. In our proposed system, the beam steer angle depends on an input electrical signal which drives the tunable lens. Therefore the beam steer angle is made to follow the variations in the input electrical drive signal. This is extremely interesting for data transfer applications as the data signal can be used as the input drive signal to the lens. The laser beam is steered according to the input data voltage levels and when the beam is incident on a photo-detector of a finite size, only a fraction of its total incident optical power is received by the photo-detector. This power contribution is proportional to the fraction of the total number of photons per unit area which are incident on the active area of the detector. The remaining photons which are not incident on the photo-detector do not contribute to the received power at the photo-detector. We present the theory of beam steering through a tunable lens and present a theoretical framework which governs data transfer through the proposed method. We also present the transfer function of the proposed system which helps us to calculate its essential theoretical performance parameters such as modulation depth and bit error rates. We also present experimental results to demonstrate efficient data transfer through the proposed method. As tunable lenses are primarily deployed in motion-free multi-focus cameras hence most of the modern portable devices such as cellphones and tablets use these lenses to operate the in-built variable focus cameras that are part of these devices. Because tunable lenses are commonly present in several different portable devices, the proposed method of data transfer between two devices is highly promising as it expands the use of the already deployed tunable lenses with

  10. A conventional HPLC-MS method for the simultaneous determination of ofloxacin and cefixime in plasma: Development and validation

    PubMed Central

    Attimarad, Mahesh V.; Alnajjar, Ahmed O.

    2013-01-01

    Objective: A simple, rapid, and sensitive high performance liquid chromatography-mass spectrometry (HPLC-MS) method was developed and validated for the simultaneous determination of ofloxacin (OFL) and cefixime (CEF) in human plasma using the moxifloxacin as internal standard. Methodology: Analytes were separated using an Agilent LCMS system equipped with a Zorbax eclipse XBD C18 column (150 mm × 4.6 mm i.d., 5 μm) and using a mobile phase consisting of a mixture of acetonitrile, methanol and 0.5% formic acid in a ratio of 23:10:67% v/v and flow rate was set at 0.6 mL/min. Plasma samples were extracted using the protein precipitation with acetonitrile and analyzed by positive ion mode. Results: The linearity of the proposed method was investigated in the concentration range of 4-500 ng/mL (r = 0.9996) for OFL and 40-6000 ng/mL (r = 0.9998) for CEF. The lower limits of quantification were 4 ng/mL and 40 ng/mL for OFL and CEF respectively, which reach the level of both drugs possibly found in human plasma. Further, the reported method was validated as per the ICH guidelines and found to be well within the acceptable range. Conclusion: The proposed method is simple, rapid, accurate, precise, and appropriate for pharmacokinetic and therapeutic drug monitoring in the clinical laboratories. PMID:24808668

  11. A space radiation transport method development

    NASA Technical Reports Server (NTRS)

    Wilson, J. W.; Tripathi, R. K.; Qualls, G. D.; Cucinotta, F. A.; Prael, R. E.; Norbury, J. W.; Heinbockel, J. H.; Tweed, J.

    2004-01-01

    Improved spacecraft shield design requires early entry of radiation constraints into the design process to maximize performance and minimize costs. As a result, we have been investigating high-speed computational procedures to allow shield analysis from the preliminary design concepts to the final design. In particular, we will discuss the progress towards a full three-dimensional and computationally efficient deterministic code for which the current HZETRN evaluates the lowest-order asymptotic term. HZETRN is the first deterministic solution to the Boltzmann equation allowing field mapping within the International Space Station (ISS) in tens of minutes using standard finite element method (FEM) geometry common to engineering design practice enabling development of integrated multidisciplinary design optimization methods. A single ray trace in ISS FEM geometry requires 14 ms and severely limits application of Monte Carlo methods to such engineering models. A potential means of improving the Monte Carlo efficiency in coupling to spacecraft geometry is given in terms of re-configurable computing and could be utilized in the final design as verification of the deterministic method optimized design. Published by Elsevier Ltd on behalf of COSPAR.

  12. A space radiation transport method development.

    PubMed

    Wilson, J W; Tripathi, R K; Qualls, G D; Cucinotta, F A; Prael, R E; Norbury, J W; Heinbockel, J H; Tweed, J

    2004-01-01

    Improved spacecraft shield design requires early entry of radiation constraints into the design process to maximize performance and minimize costs. As a result, we have been investigating high-speed computational procedures to allow shield analysis from the preliminary design concepts to the final design. In particular, we will discuss the progress towards a full three-dimensional and computationally efficient deterministic code for which the current HZETRN evaluates the lowest-order asymptotic term. HZETRN is the first deterministic solution to the Boltzmann equation allowing field mapping within the International Space Station (ISS) in tens of minutes using standard finite element method (FEM) geometry common to engineering design practice enabling development of integrated multidisciplinary design optimization methods. A single ray trace in ISS FEM geometry requires 14 ms and severely limits application of Monte Carlo methods to such engineering models. A potential means of improving the Monte Carlo efficiency in coupling to spacecraft geometry is given in terms of re-configurable computing and could be utilized in the final design as verification of the deterministic method optimized design. PMID:15880919

  13. A LC/UV/Vis method for determination of cyanocobalamin in multivitamin dietary supplements with on-line sample clean-up

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A HPLC-UV method using a two-column strategy with a switching valve for on-line sample clean-up was developed for the determination of cyanocobalamin (CN-CBL-vitamin B12, in dietary supplements. The method uses two columns, an Agilent Zorbax C8 (150 mm x 4.6 mm, 5 um particle) reversed-phase column...

  14. Structural reliability methods: Code development status

    NASA Technical Reports Server (NTRS)

    Millwater, Harry R.; Thacker, Ben H.; Wu, Y.-T.; Cruse, T. A.

    1991-01-01

    The Probabilistic Structures Analysis Method (PSAM) program integrates state of the art probabilistic algorithms with structural analysis methods in order to quantify the behavior of Space Shuttle Main Engine structures subject to uncertain loadings, boundary conditions, material parameters, and geometric conditions. An advanced, efficient probabilistic structural analysis software program, NESSUS (Numerical Evaluation of Stochastic Structures Under Stress) was developed as a deliverable. NESSUS contains a number of integrated software components to perform probabilistic analysis of complex structures. A nonlinear finite element module NESSUS/FEM is used to model the structure and obtain structural sensitivities. Some of the capabilities of NESSUS/FEM are shown. A Fast Probability Integration module NESSUS/FPI estimates the probability given the structural sensitivities. A driver module, PFEM, couples the FEM and FPI. NESSUS, version 5.0, addresses component reliability, resistance, and risk.

  15. Pulsar timing and the Fermi and AGILE missions

    NASA Astrophysics Data System (ADS)

    Weltevrede, Patrick; Possenti, Andrea; Manchester, Dick; Johnston, Simon; Kramer, Michael; Hobbs, George; Keith, Michael; Romani, Roger W.; Thompson, David J.; Thorsett, Stephen; Roberts, Mallory

    2009-10-01

    We request time to observe 160 pulsars on a regular basis in order to provide accurate ephemerides necessary for the detection of gamma-ray pulsars with the Fermi and AGILE satellites. The main science goals are to increase the number of known gamma-ray pulsars (both radio loud and radio quiet), to determine accurate pulse profiles, to characterise their high energy spectra and phase resolved spectroscopy of the brightest pulsars. In the radio, the observations will also allow us to find glitches, characterise timing noise, investigate dispersion and rotation measure variability and enhance our knowledge of single pulse phenomenology. To date, we are (co-)authors on 2 Agile papers, 4 Fermi papers, 3 radio papers and authors on 3 papers in submission. The data are contributing to the PhD theses of Lucas Guillemot and Damien Parent from the Bordeaux Fermi group.

  16. Probabilistic structural analysis methods development for SSME

    NASA Technical Reports Server (NTRS)

    Chamis, C. C.; Hopkins, D. A.

    1988-01-01

    The development of probabilistic structural analysis methods is a major part of the SSME Structural Durability Program and consists of three program elements: composite load spectra, probabilistic finite element structural analysis, and probabilistic structural analysis applications. Recent progress includes: (1) the effects of the uncertainties of several factors on the HPFP blade temperature pressure and torque, (2) the evaluation of the cumulative distribution function of structural response variables based on assumed uncertainties on primitive structural variables, and (3) evaluation of the failure probability. Collectively, the results obtained demonstrate that the structural durability of critical SSME components can be probabilistically evaluated.

  17. [Development of identification method for isopropyl citrate].

    PubMed

    Furusho, Noriko; Ohtsuki, Takashi; Tatebe-Sasaki, Chiye; Kubota, Hiroki; Sato, Kyoko; Akiyama, Hiroshi

    2014-01-01

    In Japan's Specification and Standards for Food Additive, 8th edition, two identification tests involving isopropyl citrate for detecting isopropyl alcohol and citrate are stipulated. However, these identification tests use mercury compound, which is toxic, or require a time-consuming pretreatment process. To solve these problems, an identification test method using GC-FID for detecting isopropyl alcohol was developed. In this test, a good linearity was observed in the range of 0.1-40 mg/mL of isopropyl alcohol. While investigating the pretreatment process, we found that isopropyl alcohol could be detected using GC-FID in the distillation step only, without involving any reflux step. The study also showed that the citrate moiety of isopropyl citrate was identified using the solution remaining after conducting the distillation of isopropyl alcohol. The developed identification tests for isopropyl citrate are simple and use no toxic materials. PMID:25707204

  18. Methods for developing and validating survivability distributions

    SciTech Connect

    Williams, R.L.

    1993-10-01

    A previous report explored and discussed statistical methods and procedures that may be applied to validate the survivability of a complex system of systems that cannot be tested as an entity. It described a methodology where Monte Carlo simulation was used to develop the system survivability distribution from the component distributions using a system model that registers the logical interactions of the components to perform system functions. This paper discusses methods that can be used to develop the required survivability distributions based upon three sources of knowledge. These are (1) available test results; (2) little or no available test data, but a good understanding of the physical laws and phenomena which can be applied by computer simulation; and (3) neither test data nor adequate knowledge of the physics are known, in which case, one must rely upon, and quantify, the judgement of experts. This paper describes the relationship between the confidence bounds that can be placed on survivability and the number of tests conducted. It discusses the procedure for developing system level survivability distributions from the distributions for lower levels of integration. It demonstrates application of these techniques by defining a communications network for a Hypothetical System Architecture. A logic model for the performance of this communications network is developed, as well as the survivability distributions for the nodes and links based on two alternate data sets, reflecting the effects of increased testing of all elements. It then shows how this additional testing could be optimized by concentrating only on those elements contained in the low-order fault sets which the methodology identifies.

  19. Sprint, agility, strength and endurance capacity in wheelchair basketball players

    PubMed Central

    Granados, C; Otero, M; Badiola, A; Olasagasti, J; Bidaurrazaga-Letona, I; Iturricastillo, A; Gil, SM

    2014-01-01

    The aims of the present study were, firstly, to determine the reliability and reproducibility of an agility T-test and Yo-Yo 10 m recovery test; and secondly, to analyse the physical characteristics measured by sprint, agility, strength and endurance field tests in wheelchair basketball (WB) players. 16 WB players (33.06 ± 7.36 years, 71.89 ± 21.71 kg and sitting body height 86.07 ± 6.82 cm) belonging to the national WB league participated in this study. Wheelchair sprint (5 and 20 m without ball, and 5 and 20 m with ball) agility (T-test and pick-up test) strength (handgrip and maximal pass) and endurance (Yo-Yo 10 m recovery test) were performed. T-test and Yo-Yo 10 m recovery test showed good reproducibility values (intraclass correlation coefficient, ICC = 0.74-0.94). The WB players’ results in 5 and 20 m sprints without a ball were 1.87 ± 0.21 s and 5.70 ± 0.43 s and with a ball 2.10 ± 0.30 s and 6.59 ± 0.61 s, being better than those reported in the literature. Regarding the pick-up test results (16.05 ± 0.52 s) and maximal pass (8.39 ± 1.77 m), players showed worse values than those obtained in elite players. The main contribution of the present study is the characterization of the physical performance profile of WB players using a field test battery. Furthermore, we demonstrated that the agility T-test and the aerobic Yo-Yo 10 m recovery test are reliable; consequently they may be appropriate instruments for measuring physical fitness in WB. PMID:25729153

  20. AGILE detection of a flare from PKS 1510-089

    NASA Astrophysics Data System (ADS)

    Bulgarelli, A.; Tavani, M.; Fioretti, V.; Gianotti, F.; Trifoglio, M.; Pittori, C.; Verrecchia, F.; Lucarelli, F.; Vercellone, S.; Piano, G.; Donnarumma, I.; Striani, E.; Cardillo, M.; Giuliani, A.; Mereghetti, S.; Caraveo, P.; Perotti, F.; Chen, A.; Colafrancesco, S.; Del Monte, E.; Evangelista, Y.; Feroci, M.; Lazzarotto, F.; Pacciani, L.; Soffitta, P.; Costa, E.; Lapshov, I.; Rapisarda, M.; Argan, A.; Pucella, G.; Sabatini, S.; Trois, A.; Vittorini, V.; Fuschino, F.; Galli, M.; Labanti, C.; Marisaldi, M.; Di Cocco, G.; Pellizzoni, A.; Pilia, M.; Barbiellini, G.; Vallazza, E.; Longo, F.; Morselli, A.; Picozza, P.; Prest, M.; Lipari, P.; Zanello, D.; Cattaneo, P. W.; Rappoldi, A.; Giommi, P.; Salotti, L.; Valentini, G.

    2014-08-01

    AGILE is now detecting transient gamma-ray emission above 100 MeV from a source positionally consistent with PKS 1510-089. Integrating from 2014-07-31 00:43 UT to 2014-08-02 02:15 UT, a preliminary maximum likelihood analysis yields a detection above 100 MeV positioned at Galactic coordinates (l,b) = (350.96, 40.12) +/- 0.9 (stat.) +/- 0.1 (syst.).

  1. AGILE Observations of the Gravitational-wave Event GW150914

    NASA Astrophysics Data System (ADS)

    Tavani, M.; Pittori, C.; Verrecchia, F.; Bulgarelli, A.; Giuliani, A.; Donnarumma, I.; Argan, A.; Trois, A.; Lucarelli, F.; Marisaldi, M.; Del Monte, E.; Evangelista, Y.; Fioretti, V.; Zoli, A.; Piano, G.; Munar-Adrover, P.; Antonelli, L. A.; Barbiellini, G.; Caraveo, P.; Cattaneo, P. W.; Costa, E.; Feroci, M.; Ferrari, A.; Longo, F.; Mereghetti, S.; Minervini, G.; Morselli, A.; Pacciani, L.; Pellizzoni, A.; Picozza, P.; Pilia, M.; Rappoldi, A.; Sabatini, S.; Vercellone, S.; Vittorini, V.; Giommi, P.; Colafrancesco, S.; Cardillo, M.; Galli, M.; Fuschino, F.

    2016-07-01

    We report the results of an extensive search through the AGILE data for a gamma-ray counterpart to the LIGO gravitational-wave (GW) event GW150914. Currently in spinning mode, AGILE has the potential of cover 80% of the sky with its gamma-ray instrument, more than 100 times a day. It turns out that AGILE came within a minute of the event time of observing the accessible GW150914 localization region. Interestingly, the gamma-ray detector exposed ∼65% of this region during the 100 s time intervals centered at ‑100 and +300 s from the event time. We determine a 2σ flux upper limit in the band 50 MeV–10 GeV, UL = 1.9 × 10‑8 erg cm‑2 s‑1, obtained ∼300 s after the event. The timing of this measurement is the fastest ever obtained for GW150914, and significantly constrains the electromagnetic emission of a possible high-energy counterpart. We also carried out a search for a gamma-ray precursor and delayed emission over five timescales ranging from minutes to days: in particular, we obtained an optimal exposure during the interval ‑150/‑30 s. In all these observations, we do not detect a significant signal associated with GW150914. We do not reveal the weak transient source reported by Fermi-GBM 0.4 s after the event time. However, even though a gamma-ray counterpart of the GW150914 event was not detected, the prospects for future AGILE observations of GW sources are decidedly promising.

  2. Design and characterization of frequency agile RF and microwave devices using ferroelectrics

    NASA Astrophysics Data System (ADS)

    Nath, Jayesh

    A methodology for the optimized design of tunable distributed resonators is introduced and verified. This technique enables maximum tuning with minimum degradation in quality (Q) factor. The concept of a network transformation factor and a new figure-of-merit for tunable resonators is introduced and applied to experimental data. The figure-of-merit quantifies the trade-off between tunability and Q factor for a given tuning ratio of the variable reactance device. As such, it can be extended to the design of filters, phase shifters, antennas, matching networks and other frequency-agile devices where resonant elements are used. Varactors utilizing Barium Strontium Titanate (BST) thin-film were designed and fabricated in integrated form and also in discrete form as standard 0603 components. High frequency characterization and modeling of BST varactors is described. A novel characterization technique for the intrinsic loss extraction of symmetrical two-port networks was developed and verified experimentally. Both integrated and discrete BST thin-film varactors were used to design, fabricate and characterize frequency-agile circuits. Tunable bandpass and bandstop filters and matching networks are described. A dual-mode, narrowband microstrip patch antenna with independently tunable modes was developed and characterized. Tuning and nonlinear characterization results are presented. Investigation for the use of BST thin-film varactors for voltage-controlled oscillators and phase shifters are also presented. Design parameters, fabrication issues, and processing challenges are discussed.

  3. Agile Science Operations: A New Approach for Primitive Exploration Bodies

    NASA Technical Reports Server (NTRS)

    Chien, Steve A.; Thompson, David R.; Castillo-Rogez, Julie C.; Doyle, Richard; Estlin, Tara; Mclaren, David

    2012-01-01

    Primitive body exploration missions such as potential Comet Surface Sample Return or Trojan Tour and Rendezvous would challenge traditional operations practices. Earth-based observations would provide only basic understanding before arrival and many science goals would be defined during the initial rendezvous. It could be necessary to revise trajectories and observation plans to quickly characterize the target for safe, effective observations. Detection of outgassing activity and monitoring of comet surface activity are even more time constrained, with events occurring faster than round-trip light time. "Agile science operations" address these challenges with contingency plans that recognize the intrinsic uncertainty in the operating environment and science objectives. Planning for multiple alternatives can significantly improve the time required to repair and validate spacecraft command sequences. When appropriate, time-critical decisions can be automated and shifted to the spacecraft for immediate access to instrument data. Mirrored planning systems on both sides of the light-time gap permit transfer of authority back and forth as needed. We survey relevant science objectives, identifying time bottlenecks and the techniques that could be used to speed missions' reaction to new science data. Finally, we discuss the results of a trade study simulating agile observations during flyby and comet rendezvous scenarios. These experiments quantify instrument coverage of key surface features as a function of planning turnaround time. Careful application of agile operations techniques can play a significant role in realizing the Decadal Survey plan for primitive body exploration

  4. Clustering-based urbanisation to improve enterprise information systems agility

    NASA Astrophysics Data System (ADS)

    Imache, Rabah; Izza, Said; Ahmed-Nacer, Mohamed

    2015-11-01

    Enterprises are daily facing pressures to demonstrate their ability to adapt quickly to the unpredictable changes of their dynamic in terms of technology, social, legislative, competitiveness and globalisation. Thus, to ensure its place in this hard context, enterprise must always be agile and must ensure its sustainability by a continuous improvement of its information system (IS). Therefore, the agility of enterprise information systems (EISs) can be considered today as a primary objective of any enterprise. One way of achieving this objective is by the urbanisation of the EIS in the context of continuous improvement to make it a real asset servicing enterprise strategy. This paper investigates the benefits of EISs urbanisation based on clustering techniques as a driver for agility production and/or improvement to help managers and IT management departments to improve continuously the performance of the enterprise and make appropriate decisions in the scope of the enterprise objectives and strategy. This approach is applied to the urbanisation of a tour operator EIS.

  5. An agile mask data preparation and writer dispatching approach

    NASA Astrophysics Data System (ADS)

    Hsu, Chih-tung; Chen, Y. S.; Hsin, S. C.; Tuo, Laurent C.; Schulze, Steffen F.

    2004-08-01

    An agile mask data preparation (MDP) approach is proposed to cut re-fracture cycle time as incurred by mask writer dispatching policy changes. Shorter re-fracture cycle time increases the flexibility of mask writer dispatching, as a result, mask writer's capacity can be utilized to its optimum. Preliminary results demonstrate promising benefits in MDP cycle time reduction and writer dispatching flexibility improvement. The agile MDP can save up to 40% of re-fracture cycle time. OASIS (Open Artwork System Interchange Standard) was proposed to address the GDSII file size explosion problem. However, OASIS has yet to gain wide acceptance in the mask industry. The authors envision OASIS adoption by the mask industry as a three-phase process and identify key issues of each phase from the mask manufacturer's perspective. As a long-term MDP flow reengineering project, an agile MDP and writer dispatching approach based on OASIS is proposed. The paper describes the results of an extensive evaluation on OASIS performance compared to that of GDSII, both original GDSII and post-OPC GDSII files. The file size of eighty percent of the original GDSII files is more than ten times larger compared to that of its OASIS counterpart.

  6. Observing peculiar γ-ray pulsars with AGILE

    NASA Astrophysics Data System (ADS)

    Pilia, M.; Pellizzoni, A.

    2011-08-01

    The AGILE γ-ray satellite provides large sky exposure levels (>=109 cm2 s per year on the Galactic Plane) with sensitivity peaking at E ~100 MeV where the bulk of pulsar energy output is typically released. Its ~1 μs absolute time tagging capability makes it perfectly suited for the study of γ-ray pulsars. AGILE collected a large number of γ-ray photons from EGRET pulsars (>=40,000 pulsed counts for Vela) in two years of observations unveiling new interesting features at sub-millisecond level in the pulsars' high-energy light-curves, γ-ray emission from pulsar glitches and Pulsar Wind Nebulae. AGILE detected about 20 nearby and energetic pulsars with good confidence through timing and/or spatial analysis. Among the newcomers we find pulsars with very high rotational energy losses, such as the remarkable PSR B1509-58 with a magnetic field in excess of 1013 Gauss, and PSR J2229+6114 providing a reliable identification for the previously unidentified EGRET source 3EG2227+6122. Moreover, the powerful millisecond pulsar B1821-24, in the globular cluster M28, is detected during a fraction of the observations.

  7. Effect of fence height on joint angles of agility dogs.

    PubMed

    Birch, Emily; Leśniak, Kirsty

    2013-12-01

    The Kennel Club (KC) and United Kingdom Agility (UKA) govern major dog agility competitions in the UK. Dogs are categorised into different jump heights depending on their height at the withers, with fence heights ranging from 300 to 650 mm for both organisations. Dogs fall into one of three height categories when competing under KC rules and one of four height categories under UKA rules. The aim of this study was to investigate the influence of an additional height category for agility dogs measuring over 430 mm at the withers. Jump heights were selected that related to the percentage of body height that dogs of 430 mm (7% lower) and 431 mm (51% higher) height at the withers would be encouraged to jump under UKA regulations without the addition of their fourth ('standard height') category. Joint angles were determined from anatomical markers placed on the forelimb and hind limb joints, and at six points along the vertebral column. As fence height increased, flexion of the scapulohumeral joint increased significantly for both the take-off and bascule (arc) phases of the jump. The increase in flexion as a consequence of the increase in fence height is likely to result in intensified stretching of the biceps brachii and supraspinatus muscles. In addition, increasing fence high resulted in an increase in the sacroiliac joint angle during take-off. PMID:24360736

  8. Are we unnecessarily constraining the agility of complex process-based models?

    NASA Astrophysics Data System (ADS)

    Mendoza, Pablo A.; Clark, Martyn P.; Barlage, Michael; Rajagopalan, Balaji; Samaniego, Luis; Abramowitz, Gab; Gupta, Hoshin

    2015-01-01

    In this commentary we suggest that hydrologists and land-surface modelers may be unnecessarily constraining the behavioral agility of very complex physics-based models. We argue that the relatively poor performance of such models can occur due to restrictions on their ability to refine their portrayal of physical processes, in part because of strong a priori constraints in: (i) the representation of spatial variability and hydrologic connectivity, (ii) the choice of model parameterizations, and (iii) the choice of model parameter values. We provide a specific example of problems associated with strong a priori constraints on parameters in a land surface model. Moving forward, we assert that improving hydrological models requires integrating the strengths of the "physics-based" modeling philosophy (which relies on prior knowledge of hydrologic processes) with the strengths of the "conceptual" modeling philosophy (which relies on data driven inference). Such integration will accelerate progress on methods to define and discriminate among competing modeling options, which should be ideally incorporated in agile modeling frameworks and tested through a diagnostic evaluation approach.

  9. High-Speed Time-Series CCD Photometry with Agile

    NASA Astrophysics Data System (ADS)

    Mukadam, Anjum S.; Owen, R.; Mannery, E.; MacDonald, N.; Williams, B.; Stauffer, F.; Miller, C.

    2011-12-01

    We have assembled a high-speed time-series CCD photometer named Agile for the 3.5 m telescope at Apache Point Observatory, based on the design of a photometer called Argos at McDonald Observatory. Instead of a mechanical shutter, we use the frame-transfer operation of the CCD to end an exposure and initiate the subsequent new exposure. The frame-transfer operation is triggered by the negative edge of a GPS pulse; the instrument timing is controlled directly by hardware, without any software intervention or delays. This is the central pillar in the design of Argos that we have also used in Agile; this feature makes the accuracy of instrument timing better than a millisecond. Agile is based on a Princeton Instruments Acton VersArray camera with a frame-transfer CCD, which has 1K × 1K active pixels, each of size 13 μm × 13 μm. Using a focal reducer at the Nasmyth focus of the 3.5 m telescope at Apache Point Observatory, we yield a field of view of 2.2 × 2.2 arcmin2 with an unbinned plate scale of 0.13'' pixel-1. The CCD is back-illuminated and thinned for improved blue sensitivity and provides a quantum efficiency >=80% in the wavelength range of 4500-7500 Å. The unbinned full-frame readout time can be as fast as 1.1 s this is achieved using a low-noise amplifier operating at 1 MHz with an average read noise of the order of 6.6 e rms. At the slow read rate of 100 kHz to be used for exposure times longer than a few seconds, we determine an average read noise of the order of 3.7 e rms. Agile is optimized to observe variability at short timescales from one-third of a second to several hundred seconds. The variable astronomical sources routinely observed with Agile include pulsating white dwarfs, cataclysmic variables, flare stars, planetary transits, and planetary satellite occultations.

  10. A real time pipeline to link meteorological information and TGFs detected by AGILE

    NASA Astrophysics Data System (ADS)

    Ursi, Alessandro; Tavani, Marco; Dietrich, Stefano; Marisaldi, Martino; Casella, Daniele; Sanò, Paolo; Petracca, Marco; Argan, Andrea

    2015-04-01

    Terrestrial Gamma-ray Flashes (TGFs) are brief (AGILE mission turns out to be particularly suitable to detect TGFs, because of its very wide energy range (up to 100 MeV and beyond), its optimized triggering system and its equatorial orbit. We describe a new alert service that has been developed for the AGILE satellite, whose aim is to provide "real time" meteorological information about the detected TGFs. We take advantage of the Meteosat Second Generation (MSG) satellites data to promptly identify the possible individual thunderstorm or mesoscale convective system associated to the detected TGF event and to follow its evolution in space and time. Data from other meteorological satellites, for example the GPM mission, as well as ground measurements from lightning detection network, can be integrated in the pipeline. This allows us a prompt characterization of the ground meteorological conditions at TGF time which will provide instrument independent trigger validation, fill in a database for subsequent statistical analysis, and eventually, on a longer term perspective, serve as a real time alert system open to the community.

  11. The X-31 aircraft: Advances in aircraft agility and performance

    NASA Astrophysics Data System (ADS)

    Alcorn, C. W.; Croom, M. A.; Francis, M. S.; Ross, H.

    1996-08-01

    The X-31 enhanced fighter maneuverability (EFM) demonstrator has pioneered agile flight in the post-stall flight regime and explored integrated multi-axis thrust vectoring across a broad flight envelope. Its maneuvering achievements include sustained flight up to 70 degrees angle of attack, velocity vector rolls in deep post-stall conditions, and post-stall turns from high entry to exit speeds with ultra low turning/transitional conditions. The concept of post-stall maneuverability was extensively studied in simulations preceding initiation of the X-31 program. These simulations provided a baseline for tactical utility demonstrations and vehicle design requirements. Post-stall maneuverability was not achieved without encountering and mitigating the effects of highly unsteady, asymmetric, vortex-dominated flow-fields associated with post-stall flight. Anomalies in vehicle response to control inputs were observed at high angles of attack, as were differences between simulator and actual flight parameters due to a misrepresentation of the effects of these complex flowfields. Some preliminary force and moment data for the X-31 configuration during dynamic maneuvers are provided to highlight the complex nature of the flowfield. The X-31 aircraft's enabling capabilities, including multi-axis thrust vectoring and integrated flight/propulsion control also provided performance enhancements across the entire flight envelope. In what were known as ‘quasi-tailless’ experiments, conventional aerodynamic control surfaces were used to reduce or eliminate the stabilizing influence of the vertical stabilizer, while the vehicle's multi-axis thrust vectoring capability was used for restabilization. Properly exploited, these technologies can lead to the reduction or elimination of traditional aerodynamic control surfaces, which provides profound improvements in vehicle range, weight, payload, and low observability. This review focuses on some of the principal aerodynamic issues

  12. Development of a Radial Deconsolidation Method

    SciTech Connect

    Helmreich, Grant W.; Montgomery, Fred C.; Hunn, John D.

    2015-12-01

    A series of experiments have been initiated to determine the retention or mobility of fission products* in AGR fuel compacts [Petti, et al. 2010]. This information is needed to refine fission product transport models. The AGR-3/4 irradiation test involved half-inch-long compacts that each contained twenty designed-to-fail (DTF) particles, with 20-μm thick carbon-coated kernels whose coatings were deliberately fabricated such that they would crack under irradiation, providing a known source of post-irradiation isotopes. The DTF particles in these compacts were axially distributed along the compact centerline so that the diffusion of fission products released from the DTF kernels would be radially symmetric [Hunn, et al. 2012; Hunn et al. 2011; Kercher, et al. 2011; Hunn, et al. 2007]. Compacts containing DTF particles were irradiated at Idaho National Laboratory (INL) at the Advanced Test Reactor (ATR) [Collin, 2015]. Analysis of the diffusion of these various post-irradiation isotopes through the compact requires a method to radially deconsolidate the compacts so that nested-annular volumes may be analyzed for post-irradiation isotope inventory in the compact matrix, TRISO outer pyrolytic carbon (OPyC), and DTF kernels. An effective radial deconsolidation method and apparatus appropriate to this application has been developed and parametrically characterized.

  13. DEVELOPMENT OF NDA METHODS FOR NEPTUNIUM METAL

    SciTech Connect

    C. MOSS; ET AL

    2000-10-01

    Many techniques have been developed and applied in the US and other countries for the control of the special nuclear materials (SNM) plutonium and uranium, but no standard methods exist for the determination of neptunium in bulk containers. Such methods are needed because the U.S. Department of Energy requires all Government-owned {sup 237}Np be treated as if it were SNM and the International Atomic Energy Agency is considering how to monitor this material. We present the results of the measurements of several samples of neptunium metal with a variety of techniques. Analysis of passive gamma-ray spectra uniquely identifies the material, provides isotopic ratios for contaminants, such as {sup 243}Am, and may provide information about the shielding, mass, and time since processing. Active neutron interrogation, using the delayed neutron technique in a package monitor, provides useful data even if the neptunium is shielded. The tomographic gamma scanner yields a map of the distribution of the neptunium and shielding in a container. Active photon interrogation with pulses from a 10-MeV linac produces delayed neutrons between pulses, even when the container is heavily shielded. Data from one or more of these techniques can be used to identify the material and estimate a mass in a bulk container.

  14. Method development for fecal lipidomics profiling.

    PubMed

    Gregory, Katherine E; Bird, Susan S; Gross, Vera S; Marur, Vasant R; Lazarev, Alexander V; Walker, W Allan; Kristal, Bruce S

    2013-01-15

    Robust methodologies for the analysis of fecal material will facilitate the understanding of gut (patho)physiology and its role in health and disease and will help improve care for individual patients, especially high-risk populations, such as premature infants. Because lipidomics offers a biologically and analytically attractive approach, we developed a simple, sensitive, and quantitatively precise method for profiling intact lipids in fecal material. The method utilizes two separate, complementary extraction chemistries, dichloromethane (DCM) and a methyl tert-butyl ether/hexafluoroisopropanol (MTBE) mixture, alone or with high pressure cycling. Extracts were assessed by liquid chromatography-high-resolution mass spectrometry-based profiling with all ion higher energy collisional dissociation fragmentation in both positive and negative ionization modes. This approach provides both class-specific and lipid-specific fragments, enhancing lipid characterization. Solvents preferentially extracted lipids based on hydrophobicity. More polar species preferred MTBE; more hydrophobic compounds preferred DCM. Pressure cycling differentially increased the yield of some lipids. The platform enabled analysis of >500 intact lipophilic species with over 300 lipids spanning 6 LIPID MAPS categories identified in the fecal matter from premature infants. No previous report exists that provides these data; thus, this study represents a new paradigm for assessing nutritional health, inflammation, and infectious disease in vulnerable populations. PMID:23210743

  15. Methods development for total organic carbon accountability

    NASA Technical Reports Server (NTRS)

    Benson, Brian L.; Kilgore, Melvin V., Jr.

    1991-01-01

    This report describes the efforts completed during the contract period beginning November 1, 1990 and ending April 30, 1991. Samples of product hygiene and potable water from WRT 3A were supplied by NASA/MSFC prior to contract award on July 24, 1990. Humidity condensate samples were supplied on August 3, 1990. During the course of this contract chemical analyses were performed on these samples to qualitatively determine specific components comprising, the measured organic carbon concentration. In addition, these samples and known standard solutions were used to identify and develop methodology useful to future comprehensive characterization of similar samples. Standard analyses including pH, conductivity, and total organic carbon (TOC) were conducted. Colorimetric and enzyme linked assays for total protein, bile acid, B-hydroxybutyric acid, methylene blue active substances (MBAS), urea nitrogen, ammonia, and glucose were also performed. Gas chromatographic procedures for non-volatile fatty acids and EPA priority pollutants were also performed. Liquid chromatography was used to screen for non-volatile, water soluble compounds not amenable to GC techniques. Methods development efforts were initiated to separate and quantitate certain chemical classes not classically analyzed in water and wastewater samples. These included carbohydrates, organic acids, and amino acids. Finally, efforts were initiated to identify useful concentration techniques to enhance detection limits and recovery of non-volatile, water soluble compounds.

  16. The technology base for agile manufacturing

    NASA Technical Reports Server (NTRS)

    Brost, R. C.; Strip, D. R.; Eicker, P. J.

    1993-01-01

    The effective use of information is a critical problem faced by manufacturing organizations that must respond quickly to market changes. As product runs become shorter, rapid and efficient development of product manufacturing facilities becomes crucial to commercial success. Effective information utilization is a key element to successfully meeting these requirements. This paper reviews opportunities for developing technical solutions to information utilization problems within a manufacturing enterprise and outlines a research agenda for solving these problems.

  17. The technology base for agile manufacturing

    NASA Astrophysics Data System (ADS)

    Brost, R. C.; Strip, D. R.; Eicker, P. J.

    1993-02-01

    The effective use of information is a critical problem faced by manufacturing organizations that must respond quickly to market changes. As product runs become shorter, rapid and efficient development of product manufacturing facilities becomes crucial to commercial success. Effective information utilization is a key element to successfully meeting these requirements. This paper reviews opportunities for developing technical solutions to information utilization problems within a manufacturing enterprise and outlines a research agenda for solving these problems.

  18. Interactive radio instruction: developing instructional methods.

    PubMed

    Friend, J

    1989-01-01

    The USAID has, since 1972, funded the development of a new methodology for educational radio for young children through 3 projects: the Radio Mathematics PRoject of Nicaragua, the Radio Language Arts Project of Kenya, and the Radio Science PRoject of Papua New Guinea. These projects developed math programs for grades 1-4 and English as a second language for grades 1-3; programs to teach science in grades 4-6 are now being developed. Appropriate techniques were developed to engage young children actively in the learning process. Lessons are planned as a "conversation" between the children and the radio; scripts are written as 1/2 of a dialogue, with pauses carefully timed so that written as 12 of a dialogue, with pauses carefully timed so that students can contribute their 1/2. Teaching techniques used in all 3 projects include choral responses, simultaneous individual seatwork, and activities using simple materials such as pebbles and rulers. Certain techniques were specific to the subject being taught, or to the circumstances in which the lessons were to be used. Patterned oral drill was used frequently in the English lessons, including sound-cued drills. "Deferred" oral responses were used often in the math lessons. In this method, the children are instructed to solve a problem silently, not giving the answer aloud until requested, thus allowing time for even the slower children to participate. "One-child" questions were used in both English and science: the radio asks a question to be answered by a single child, who is selected on the spot by the classroom teacher. This allows for open-ended questions, but also requires constant supervision of the classroom teacher. Songs and games were used in all programs, and extensively for didactic purposes in the teaching of English. Instructions for science activities are often more complex than in other courses, particularly when the children are using science apparatus, especially when they work in pairs to share scarce

  19. Team-based work and work system balance in the context of agile manufacturing.

    PubMed

    Yauch, Charlene A

    2007-01-01

    Manufacturing agility is the ability to prosper in an environment characterized by constant and unpredictable change. The purpose of this paper is to analyze team attributes necessary to facilitate agile manufacturing, and using Balance Theory as a framework, it evaluates the potential positive and negative impacts related to these team attributes that could alter the balance of work system elements and resulting "stress load" experienced by persons working on agile teams. Teams operating within the context of agile manufacturing are characterized as multifunctional, dynamic, cooperative, and virtual. A review of the literature relevant to each of these attributes is provided, as well as suggestions for future research. PMID:16631101

  20. Effects of an over-the-counter vented mouthguard on cardiorespiratory responses to exercise and physical agility.

    PubMed

    Bailey, Stephen P; Willauer, Thomas J; Balilionis, Gytis; Wilson, Laura E; Salley, John T; Bailey, Elizabeth K; Strickland, Tony L

    2015-03-01

    Many athletes avoid using mouthguards because they believe that they impair their ability to breath and negatively affect performance. Recently, some manufacturers have developed "vented" mouthguards (VentMGs) to address this concern. The purposes of this investigation were to describe the impact of a commercially available "vented" boil-and-bite mouthguard on the physiological responses to graded exercise and to determine whether the use of the same mouthguard influences performance during traditional physical agility tests. Recreationally trained males (n = 15) (age = 24 ± 1 year; (Equation is included in full-text article.)= 43.5 ± 1.9 ml·kg·min; body mass index = 25.2 ± 0.9) completed 3 randomly assigned trials where they wore no mouthguard (control), a traditional mouthguard (TradMG), or a VentMG. During each trial, subjects completed a modified maximal exercise test on a cycle ergometer and a series of physical agility tests (40-m dash, vertical leap, broad jump, 3-cone drill, and shuttle run). No differences were seen between control and the TradMG in any cardiorespiratory measures at any time during the maximal exercise test. Ventilation and blood lactate were lower (p ≤ 0.05) during VentMG at 200 W and at MAX; however, no differences in (Equation is included in full-text article.)were observed. Although TradMG had no impact on physical agility, VentMG produced a higher (1.9 cm; p = 0.03) vertical leap than control. Both mouthguard conditions negatively affected perceptions of breathability, comfort, and ability to communicate, but no differences existed between the 2 conditions. These findings confirm that TradMG has no negative impact on physiological function during exercise and physical agility; however, VentMG may have a positive impact at higher workload and on vertical leap. PMID:25264671

  1. Failure-tolerant control for small agile satellites using single-gimbal control moment gyros and magnetic torquers

    NASA Astrophysics Data System (ADS)

    Meng, Tao; Matunaga, Saburo

    2012-04-01

    This paper focuses on the attitude control problem of small agile satellites using single-gimbal control moment gyros (CMG) and magnetic torquers (MTQ). CMGs are regarded as effective torque generators for agile satellites because of their torque amplification capability. However, they are vulnerable to failure due to their complex inner mechanism. In this paper, different failure cases of CMGs are analyzed. A flexible failure-tolerant control strategy is developed by automatically redistributing the required control torque among the operating CMGs and MTQs, with a variable limiter to accommodate the actuator dynamics changes introduced by CMG failures. The performances of maneuvers about different directions under different failure cases are also discussed and examined. Numerical simulations demonstrate that the proposed strategy maintains certain agility in the cases of one or two CMGs failing. Moreover, a survival strategy with only one CMG left is also verified. Both sun-pointing stabilization and earth-pointing stabilization can be achieved in this case, which fulfill some basic mission requirements.

  2. Analysis of global Terrestrial Gamma Ray Flashes distribution and special focus on AGILE detections over South America

    NASA Astrophysics Data System (ADS)

    Fabró, Ferran; Montanyà, Joan; Marisaldi, Martino; van der Velde, Oscar A.; Fuschino, Fabio

    2015-03-01

    Global distribution of the Terrestrial Gamma-ray Flashes (TGFs) detected by AGILE and RHESSI for the period from March 2009 to July 2012 has been analysed. A fourth TGF production region has been distinguished over the Pacific. It is confirmed that TGF occurrence follows the Intertropical Convergence Zone (ITCZ) seasonal migration and prefers afternoons. TGF/lightning ratio appears to be lower over America than other regions suggesting that meteorological regional differences are important for the TGF production. Diurnal cycle of TGFs peaks in the afternoon suggesting that Convective Available Potential Energy (CAPE) and convection are important for TGF production. Moreover all AGILE passages over South America in the same period have been analysed to find meteorological preferences for TGF occurrence. In each passage the analysis of Cloud Top Altitude (CTA), CAPE, number of strokes, number of storms and coverage area of clouds with temperatures below -70 °C (Cloud Top Coverage area, CTC) are computed. On average, AGILE has been exposed to 19,100 strokes between each TGF representing ∼68 h of exposure over active storms. High CAPE values, high cloud tops and high stroke occurrence suggest that meteorological conditions conducive to vigorous and electrically active storms are important for TGF production. It is shown that a high number of thunderstorms is preferable for TGF production which may be explained by a greater chance of the presence of a thunderstorm in the best development stage for TGF production. High tropopause altitude seems to be important but not primordial for TGF production.

  3. Development and Validation of an HPLC Method for Simultaneous Determination of Rifampicin, Isoniazid, Pyrazinamide, and Ethambutol Hydrochloride in Pharmaceutical Formulations.

    PubMed

    Chellini, Paula R; Lages, Eduardo B; Franco, Pedro H C; Nogueira, Fernando H A; César, Isabela C; Pianetti, Gerson A

    2015-01-01

    Tuberculosis treatment consists of a fixed dose combination of rifampicin (RIF), isoniazid (INH), pyrazinamide (PYZ), and ethambutol hydrochloride (EMB). The combined treatment using various drugs is necessary for patient curing, without recrudescence, and for prevention of drug-resistant mutants, which may occur during treatment. An HPLC-diode array detector (DAD) method for the simultaneous determination of RIF, INH, PYZ, and EMB in fixed dose combination tablets was developed and validated. Chromatographic experiments were performed on an Agilent 1200 HPLC system, and the separation was carried out on a Purospher STAR RP18e (250×4.6 mm id, 5 μm, Merck) analytical column. Gradient elution was carried out with a mobile phase of 20 mM monobasic sodium phosphate buffer with 0.2% triethylamine (pH 7.0) and acetonitrile at a flow rate of 1.5 mL/min. The total run time was 12 min, and the re-equilibration time was 5 min. EMB detection was performed at 210 nm, and RIF, INH, and PYZ were detected at 238 nm, using a DAD. The method proved to be specific, linear (r2>0.99), precise (RSD<2%), accurate, and robust and may be applied to the QC analysis of pharmaceutical formulations. PMID:26525241

  4. Green analytical method development for statin analysis.

    PubMed

    Assassi, Amira Louiza; Roy, Claude-Eric; Perovitch, Philippe; Auzerie, Jack; Hamon, Tiphaine; Gaudin, Karen

    2015-02-01

    Green analytical chemistry method was developed for pravastatin, fluvastatin and atorvastatin analysis. HPLC/DAD method using ethanol-based mobile phase with octadecyl-grafted silica with various grafting and related-column parameters such as particle sizes, core-shell and monolith was studied. Retention, efficiency and detector linearity were optimized. Even for column with particle size under 2 μm, the benefit of keeping efficiency within a large range of flow rate was not obtained with ethanol based mobile phase compared to acetonitrile one. Therefore the strategy to shorten analysis by increasing the flow rate induced decrease of efficiency with ethanol based mobile phase. An ODS-AQ YMC column, 50 mm × 4.6 mm, 3 μm was selected which showed the best compromise between analysis time, statin separation, and efficiency. HPLC conditions were at 1 mL/min, ethanol/formic acid (pH 2.5, 25 mM) (50:50, v/v) and thermostated at 40°C. To reduce solvent consumption for sample preparation, 0.5mg/mL concentration of each statin was found the highest which respected detector linearity. These conditions were validated for each statin for content determination in high concentrated hydro-alcoholic solutions. Solubility higher than 100mg/mL was found for pravastatin and fluvastatin, whereas for atorvastatin calcium salt the maximum concentration was 2mg/mL for hydro-alcoholic binary mixtures between 35% and 55% of ethanol in water. Using atorvastatin instead of its calcium salt, solubility was improved. Highly concentrated solution of statins offered potential fluid for per Buccal Per-Mucous(®) administration with the advantages of rapid and easy passage of drugs. PMID:25582487

  5. Relationships Between Reactive Agility Movement Time and Unilateral Vertical, Horizontal, and Lateral Jumps.

    PubMed

    Henry, Greg J; Dawson, Brian; Lay, Brendan S; Young, Warren B

    2016-09-01

    Henry, GJ, Dawson, B, Lay, BS, and Young, WB. Relationships between reactive agility movement time and unilateral vertical, horizontal, and lateral jumps. J Strength Cond Res 30(9): 2514-2521, 2016-This study compared reactive agility movement time and unilateral (vertical, horizontal, and lateral) jump performance and kinetics between dominant and nondominant legs in Australian rules footballers (n = 31) to investigate the role of leg strength characteristics in reactive agility performance. Jumps involved jumping forward on 1 leg, then for maximum height or horizontal or lateral distance. Agility and movement time components of reactive agility were assessed using a video-based test. Correlations between each of the jumps were strong (r = -0.62 to -0.77), but between the jumps and agility movement time the relationships were weak (r = -0.25 to -0.33). Dominant leg performance was superior in reactive agility movement time (4.5%; p = 0.04), lateral jump distance (3%; p = 0.008), and lateral reactive strength index (4.4%; p = 0.03) compared with the nondominant leg. However, when the subjects were divided into faster and slower performers (based on their agility movement times) the movement time was significantly quicker in the faster group (n = 15; 12%; p < 0.001), but no differences in jump performance or kinetics were observed. Therefore, although the capacity for jumps to predict agility performance seems limited, factors involved in producing superior lateral jump performance in the dominant leg may also be associated with advantages in agility performance in that leg. However, because reactive strength as measured by unilateral jumps seems to play a limited role in reactive agility performance and other factors such as skill, balance, and coordination, and also cognitive and decision-making factors, are likely to be more important. PMID:23820562

  6. RF stimulus generator with agile modulation features

    NASA Astrophysics Data System (ADS)

    Boychuk, Bohdan; Larkin, Calvin W., Jr.

    The design and capabilities of a microwave/millimeter-wave stimulus generator with deviations and modulation rates up to 500 MHz are described. The oscillator of the system is a combination of YIG and varactor-tuned oscillators (VTO); the oscillator generates a fixed baseband signal with the required modulation characteristics in S-band and then translates this signal to the desired output frequency while preserving all modulation characteristics. The baseband FM loop, which consists of a switchable loop filter, an external frequency-hopping input, and the hyperabrupt VTO; the methods used to obtain frequency modulation; and the implementation of amplitude, phase, and pulse modulations are examined. Consideration is given to the X-band phase-locked source and the synchronizer and YIG circuitry. The RF stimulus generator is applicable to electronic warfare ATE.

  7. Architecture and performances of the AGILE Telemetry Preprocessing System (TMPPS)

    NASA Astrophysics Data System (ADS)

    Trifoglio, M.; Bulgarelli, A.; Gianotti, F.; Lazzarotto, F.; Di Cocco, G.; Fuschino, F.; Tavani, M.

    2008-07-01

    AGILE is an Italian Space Agency (ASI) satellite dedicated to high energy Astrophysics. It was launched successfully on 23 April 2007, and it has been operated by the AGILE Ground Segment, consisting of the Ground Station located in Malindi (Kenia), the Mission Operations Centre (MOC) and the AGILE Data Centre (ADC) established in Italy, at Telespazio in Fucino and at the ASI Science Data Centre (ASDC) in Frascati respectively. Due to the low equatorial orbit at ~ 530 Km. with inclination angle of ~ 2.5°, the satellite passes over the Ground Station every ~ 100'. During the visibility period of . ~ 12', the Telemetry (TM) is down linked through two separated virtual channels, VC0 and VC1. The former is devoted to the real time TM generated during the pass at the average rate of 50 Kbit/s and is directly relayed to the Control Centre. The latter is used to downlink TM data collected on the satellite on-board mass memory during the non visibility period. This generates at the Ground Station a raw TM file of up to 37 MByte. Within 20' after the end of the contact, both the real time and mass memory TM arrive at ADC through the dedicated VPN ASINet. Here they are automatically detected and ingested by the TMPPS pipeline in less than 5 minutes. The TMPPS archives each TM file and sorts its packets into one stream for each of the different TM layout. Each stream is processed in parallel in order to unpack the various telemetry field and archive them into suitable FITS files. Each operation is tracked into a MySQL data base which interfaces the TMPPS pipeline to the rest of the scientific pipeline running at ADC. In this paper the architecture and the performance of the TMPPS will be described and discussed.

  8. Agility in adversity: Vaccines on Demand.

    PubMed

    De Groot, Anne S; Moise, Leonard; Olive, David; Einck, Leo; Martin, William

    2016-09-01

    Is the US ready for a biological attack using Ebola virus or Anthrax? Will vaccine developers be able to produce a Zika virus vaccine, before the epidemic spreads around the world? A recent report by The Blue Ribbon Study Panel on Biodefense argues that the US is not ready for these challenges, however, technologies and capabilities that could address these deficiencies are within reach. Vaccine technologies have advanced and readiness has improved in recent years, due to advances in sequencing technology and computational power making the 'vaccines on demand' concept a reality. Building a robust strategy to design effective biodefense vaccines from genome sequences harvested by real-time biosurveillance will benefit from technologies that are being brought to bear on the cancer cure 'moonshot'. When combined with flexible vaccine production platforms, vaccines on demand will relegate expensive and, in some cases, insufficiently effective vaccine stockpiles to the dust heap of history. PMID:27389971

  9. An agile enterprise regulation architecture for health information security management.

    PubMed

    Chen, Ying-Pei; Hsieh, Sung-Huai; Cheng, Po-Hsun; Chien, Tsan-Nan; Chen, Heng-Shuen; Luh, Jer-Junn; Lai, Jin-Shin; Lai, Feipei; Chen, Sao-Jie

    2010-09-01

    Information security management for healthcare enterprises is complex as well as mission critical. Information technology requests from clinical users are of such urgency that the information office should do its best to achieve as many user requests as possible at a high service level using swift security policies. This research proposes the Agile Enterprise Regulation Architecture (AERA) of information security management for healthcare enterprises to implement as part of the electronic health record process. Survey outcomes and evidential experiences from a sample of medical center users proved that AERA encourages the information officials and enterprise administrators to overcome the challenges faced within an electronically equipped hospital. PMID:20815748

  10. Flexible Conveyance Control System for Agile Manufacturing

    NASA Astrophysics Data System (ADS)

    Uchiyama, Kazuhisa; Uchimura, Keiichi; Yoshikawa, Takeru; Shishino, Satoru; Hu, Zhencheng

    The control of conveyance between processes still relies on the engineer's experience. It is difficult to correspond to the change in the conveyance layout due to the expansion and reduction of production and the breakdown of conveyance devices. In this paper, we propose a conveyance control system that can adapt to changes in the conveyance layout and we aim at the improvement of the amount of total conveyance. First of all, the system is divided into the part where the conveyance layout is made a data base and the part where the conveyance control that uses the congestion index is done. Therefore, it is possible to deal flexibly by changing the data base part without changing the conveyance control part when it is necessary to change the conveyance layout suddenly. In all the combinations of the conveyance layout and the turning on pattern used as a result of the simulation, the proposed conveyance control method became a great result by the amount of total conveyance.

  11. Simplified universal method for determining electrolyte temperatures in a capillary electrophoresis instrument with forced-air cooling.

    PubMed

    Patel, Kevin H; Evenhuis, Christopher J; Cherney, Leonid T; Krylov, Sergey N

    2012-03-01

    Temperature increase due to resistive electrical heating is an inherent limitation of capillary electrophoresis (CE). Active cooling systems are used to decrease the temperature of the capillary, but their capacity is limited; and in addition, they leave "hot spots" at the detection interface and at the capillary ends. Until recently, the matter was complicated by the lack of a fast and generic method for temperature determination in efficiently and inefficiently cooled regions of the capillary. Our group recently introduced such a method, termed "Universal Method for determining Electrolyte Temperatures" (UMET). UMET is a probe-less approach that requires only measuring current versus voltage for different voltages and processing the data using an iterative algorithm. Here, we apply UMET to develop a Simplified Universal Method of Temperature Determination (SUMET) for a CE instrument with a forced-air cooling system using an Agilent 7100 CE instrument (Agilent Technologies, Saint Laurent, Quebec, Canada) as an example. We collected a wide set of empirical voltage-current data for a variety of buffers and capillary diameters. We further constructed empirical equations for temperature calculation in efficiently and inefficiently cooled parts of the capillary that require only the data from a single 1-min voltage-current measurement. The equations are specific for the Agilent 7100 CE instrument (Agilent Technologies) but can be applied to all kinds of capillaries and buffers. Similar SUMET approaches can be developed for other CE instruments with forced-air cooling using our approach. PMID:22528428

  12. Enabler for the agile virtual enterprise

    NASA Astrophysics Data System (ADS)

    Fuerst, Karl; Schmidt, Thomas; Wippel, Gerald

    2001-10-01

    In this presentation, a new approach for a flexible low-cost Internet extended enterprise (project FLoCI-EE) will be presented. FLoCI-EE is a project in the fifth framework program of the European commission with 8 partners from 4 countries, which started in January 2001 and will be finished in December 2003. The main objective of FLoCI-EE is the development of a software prototype, which enables flexible enterprise cooperation with the aim to design, manufacture and sell products commonly, independent of enterprise borderlines. The needed IT-support includes functions of product data management (PDM), enterprise resource planning (ERP), supply chain management (SCM) and customer relationship management (CRM). Especially for small and medium sized enterprises, existing solutions are too expensive and inflexible to be of use under current turbulent market conditions. The second part of this paper covers the item Web Services, because in the role-specific support approach of FLoCI-EE, there are user- interface-components, which are tailored for specific roles in an enterprise. These components integrate automatically the services of the so-called basic-components, and the externally offered Web Services like UDDI.

  13. Lean and Agile Precision Manufacturing Systems

    NASA Astrophysics Data System (ADS)

    Slocum, Alexander H.

    2002-01-01

    A quasi-kinematic coupling (QKC) is an alignment interface that can be used to make low-cost assemblies with sub-micron precision and/or sealing contact. Unlike kinematic couplings that rely on point contacts formed by mating balls in v-grooves, quasi-kinematic couplings are based on arc contacts formed by mating three balls with three axisymmetric grooves. Though a quasi-kinematic coupling is technically not an exact constraint coupling, proper design of the contacts can produce a weakly over constrained coupling that emulates an exact constraint coupling. This paper covers the practical design of quasi-kinematic couplings and derives the theory that predicts quasi-kinematic coupling stiffness. A metric of over constraint is presented and used to develop recommended practices for minimizing the over constraint in quasi-kinematic couplings. Experimental results are provided to show that quasi-kinematic couplings can provide repeatability (1/4 micron) that is comparable to exact constraint couplings.

  14. Agile delivery of protein therapeutics to CNS.

    PubMed

    Yi, Xiang; Manickam, Devika S; Brynskikh, Anna; Kabanov, Alexander V

    2014-09-28

    A variety of therapeutic proteins have shown potential to treat central nervous system (CNS) disorders. Challenge to deliver these protein molecules to the brain is well known. Proteins administered through parenteral routes are often excluded from the brain because of their poor bioavailability and the existence of the blood-brain barrier (BBB). Barriers also exist to proteins administered through non-parenteral routes that bypass the BBB. Several strategies have shown promise in delivering proteins to the brain. This review, first, describes the physiology and pathology of the BBB that underscore the rationale and needs of each strategy to be applied. Second, major classes of protein therapeutics along with some key factors that affect their delivery outcomes are presented. Third, different routes of protein administration (parenteral, central intracerebroventricular and intraparenchymal, intranasal and intrathecal) are discussed along with key barriers to CNS delivery associated with each route. Finally, current delivery strategies involving chemical modification of proteins and use of particle-based carriers are overviewed using examples from literature and our own work. Whereas most of these studies are in the early stage, some provide proof of mechanism of increased protein delivery to the brain in relevant models of CNS diseases, while in few cases proof of concept had been attained in clinical studies. This review will be useful to broad audience of students, academicians and industry professionals who consider critical issues of protein delivery to the brain and aim developing and studying effective brain delivery systems for protein therapeutics. PMID:24956489

  15. Agile Delivery of Protein Therapeutics to CNS

    PubMed Central

    Yi, Xiang; Manickam, Devika S.; Brynskikh, Anna; Kabanov, Alexander V.

    2014-01-01

    A variety of therapeutic proteins have shown potential to treat central nervous system (CNS) disorders. Challenge to deliver these protein molecules to the brain is well known. Proteins administered through parenteral routes are often excluded from the brain because of their poor bioavailability and the existence of the blood-brain barrier (BBB). Barriers also exist to proteins administered through non-parenteral routes that bypass the BBB. Several strategies have shown promise in delivering proteins to the brain. This review, first, describes the physiology and pathology of the BBB that underscore the rationale and needs of each strategy to be applied. Second, major classes of protein therapeutics along with some key factors that affect their delivery outcomes are presented. Third, different routes of protein administration (parenteral, central intracerebroventricular and intraparenchymal, intranasal and intrathecal) are discussed along with key barriers to CNS delivery associated with each route. Finally, current delivery strategies involving chemical modification of proteins and use of particle-based carriers are overviewed using examples from literature and our own work. Whereas most of these studies are in the early stage, some provide proof of mechanism of increased protein delivery to the brain in relevant models of CNS diseases, while in few cases proof of concept had been attained in clinical studies. This review will be useful to broad audience of students, academicians and industry professionals who consider critical issues of protein delivery to the brain and aim developing and studying effective brain delivery systems for protein therapeutics. PMID:24956489

  16. HEASD PM RESEARCH METHODS: PARTICLE METHODS EVALUATION AND DEVELOPMENT

    EPA Science Inventory

    The FRM developed by NERL forms the backbone of the EPA's national monitoring strategy. It is the measurement that defines attainment of the new standard. However, the agency has numerous other needs in assessing the physical and chemical characteristics of ambient fine particl...

  17. Impact of Business Intelligence and IT Infrastructure Flexibility on Competitive Advantage: An Organizational Agility Perspective

    ERIC Educational Resources Information Center

    Chen, Xiaofeng

    2012-01-01

    There is growing use of business intelligence (BI) for better management decisions in industry. However, empirical studies on BI are still scarce in academic research. This research investigates BI from an organizational agility perspective. Organizational agility is the ability to sense and respond to market opportunities and threats with speed,…

  18. Renewed gamma-ray activity of the Blazar 3C 454.3 detected by AGILE

    NASA Astrophysics Data System (ADS)

    Bulgarelli, A.; Parmiggiani, N.; Fioretti, V.; Zoli, A.; Lucarelli, F.; Verrecchia, F.; Pittori, C.; Vercellone, S.; Piano, G.; Munar-Adrover, P.; Tavani, M.; Donnarumma, I.; Striani, E.; Cardillo, M.; Gianotti, F.; Trifoglio, M.; Giuliani, A.; Mereghetti, S.; Caraveo, P.; Perotti, F.; Chen, A.; Argan, A.; Costa, E.; Del Monte, E.; Evangelista, Y.; Feroci, M.; Lazzarotto, F.; Lapshov, I.; Pacciani, L.; Soffitta, P.; Sabatini, S.; Vittorini, V.; Pucella, G.; Rapisarda, M.; Di Cocco, G.; Fuschino, F.; Galli, M.; Labanti, C.; Marisaldi, M.; Pellizzoni, A.; Pilia, M.; Trois, A.; Barbiellini, G.; Vallazza, E.; Longo, F.; Morselli, A.; Picozza, P.; Prest, M.; Lipari, P.; Zanello, D.; Cattaneo, P. W.; Rappoldi, A.; Colafrancesco, S.; Ferrari, A.; Antonelli, A.; Giommi, P.; Salotti, L.; Valentini, G.; D'Amico, F.

    2016-06-01

    The AGILE satellite is detecting a significant enhancement in gamma-ray activity from the FSRQ 3C 454.3 (known as 1AGLR J2254+1609) since the recent AGILE ATel #9157, and the optical activity reported in ATel #9150.

  19. Built To Last: Using Iterative Development Models for Sustainable Scientific Software Development

    NASA Astrophysics Data System (ADS)

    Jasiak, M. E.; Truslove, I.; Savoie, M.

    2013-12-01

    In scientific research, software development exists fundamentally for the results they create. The core research must take focus. It seems natural to researchers, driven by grant deadlines, that every dollar invested in software development should be used to push the boundaries of problem solving. This system of values is frequently misaligned with those of the software being created in a sustainable fashion; short-term optimizations create longer-term sustainability issues. The National Snow and Ice Data Center (NSIDC) has taken bold cultural steps in using agile and lean development and management methodologies to help its researchers meet critical deadlines, while building in the necessary support structure for the code to live far beyond its original milestones. Agile and lean software development and methodologies including Scrum, Kanban, Continuous Delivery and Test-Driven Development have seen widespread adoption within NSIDC. This focus on development methods is combined with an emphasis on explaining to researchers why these methods produce more desirable results for everyone, as well as promoting developers interacting with researchers. This presentation will describe NSIDC's current scientific software development model, how this addresses the short-term versus sustainability dichotomy, the lessons learned and successes realized by transitioning to this agile and lean-influenced model, and the current challenges faced by the organization.

  20. Development and Validation of a Novel Stability-Indicating RP-HPLC Method for the Simultaneous Determination of Halometasone, Fusidic Acid, Methylparaben, and Propylparaben in Topical Pharmaceutical Formulation.

    PubMed

    Goswami, Nishant; Gupta, V Rama Mohan; Jogia, Hitesh A

    2013-06-01

    A stability-indicating reversed-phase high-performance liquid chromatography (RP-HPLC) method was developed for the simultaneous determination of halometasone, fusidic acid, methylparaben, and propylparaben in topical pharmaceutical formulation. The desired chromatographic separation was achieved on an Agilent Zorbax CN (Cyano), 5 μm (250 × 4.6 mm) column using gradient elution at 240 nm detector wavelength. The optimized mobile phase consisted of a mixture of 0.01 M phosphate buffer and 0.1% orthophosphoric acid, pH-adjusted to 2.5 with an ammonia solution as solvent-A and acetonitrile as solvent-B. The developed method separated halometasone, fusidic acid, methylparaben, and propylparaben in the presence of known impurities/degradation products. The stability-indicating capability was established by forced degradation experiments and separation of known and unknown degradation products. The developed RP-HPLC method was validated according to the International Conference on Harmonization (ICH) guidelines. This validated method was applied for the simultaneous estimation of HM, FA, MP, and PP in commercially available cream samples. Further, the method can be extended for the estimation of HM, FA, MP, and PP in various commercially available dosage forms. PMID:23833716

  1. Quantitation of acotiamide in rat plasma by UHPLC-Q-TOF-MS: method development, validation and application to pharmacokinetics.

    PubMed

    Patel, Prinesh N; Kalariya, Pradipbhai D; Swamy, Challa Veerabhadra; Gananadhamu, S; Srinivas, R

    2016-03-01

    A novel, sensitive and selective ultra-high-performance liquid chromatography-electrospray ionization mass spectrometry method was developed and validated for the quantification of acotiamide (ACT), a first-in-class drug used in functional dyspepsia, in rat plasma. A simple protein precipitation method with acetonitrile as precipitating solvent was used to extract ACT from rat plasma. ACT and an internal standard (mirabegron, IS) were separated on an Agilent poroshell EC C18 column (50 × 3.0 mm, 2.7 µm) using methanol-10 mM ammonium acetate binary gradient mobile phase at a flow rate of 0.4 mL/min over 4 min run time. Detection was performed using target ions of [M + H](+) at m/z 451.2010 for ACT and m/z 397.1693 for IS in selective ion mode. The method was validated in the calibration range of 1.31-1000 ng/mL. All the validation parameters were well within the limits. The method demonstrated good performances in terms of intra- and inter-day precision (3.27-12.60% CV) and accuracy (87.96-104.94%). Thus the present ultra-high-pressure liquid chromatograhy-high-resolution mass spectrometry method for determination of ACT in rat plasma, is highly sensitive and rapid with a short run-time of 4 min, can be suitable for high sample throughput and for large batches of biological samples in pharmacokinetic studies. This method can be extended to measure plasma concentrations of ACT in humans to understand drug metabolism, drug interaction and adverse effects. PMID:26153099

  2. Development and application of a validated HPLC method for the analysis of dissolution samples of levothyroxine sodium drug products.

    PubMed

    Collier, J W; Shah, R B; Bryant, A R; Habib, M J; Khan, M A; Faustino, P J

    2011-02-20

    A rapid, selective, and sensitive gradient HPLC method was developed for the analysis of dissolution samples of levothyroxine sodium tablets. Current USP methodology for levothyroxine (L-T(4)) was not adequate to resolve co-elutants from a variety of levothyroxine drug product formulations. The USP method for analyzing dissolution samples of the drug product has shown significant intra- and inter-day variability. The sources of method variability include chromatographic interferences introduced by the dissolution media and the formulation excipients. In the present work, chromatographic separation of levothyroxine was achieved on an Agilent 1100 Series HPLC with a Waters Nova-pak column (250 mm × 3.9 mm) using a 0.01 M phosphate buffer (pH 3.0)-methanol (55:45, v/v) in a gradient elution mobile phase at a flow rate of 1.0 mL/min and detection UV wavelength of 225 nm. The injection volume was 800 μL and the column temperature was maintained at 28°C. The method was validated according to USP Category I requirements. The validation characteristics included accuracy, precision, specificity, linearity, and analytical range. The standard curve was found to have a linear relationship (r(2)>0.99) over the analytical range of 0.08-0.8 μg/mL. Accuracy ranged from 90 to 110% for low quality control (QC) standards and 95 to 105% for medium and high QC standards. Precision was <2% at all QC levels. The method was found to be accurate, precise, selective, and linear for L-T(4) over the analytical range. The HPLC method was successfully applied to the analysis of dissolution samples of marketed levothyroxine sodium tablets. PMID:20947276

  3. Development and application of a validated HPLC method for the analysis of dissolution samples of levothyroxine sodium drug products

    PubMed Central

    Collier, J.W.; Shah, R.B.; Bryant, A.R.; Habib, M.J.; Khan, M.A.; Faustino, P.J.

    2011-01-01

    A rapid, selective, and sensitive gradient HPLC method was developed for the analysis of dissolution samples of levothyroxine sodium tablets. Current USP methodology for levothyroxine (l-T4) was not adequate to resolve co-elutants from a variety of levothyroxine drug product formulations. The USP method for analyzing dissolution samples of the drug product has shown significant intra- and inter-day variability. The sources of method variability include chromatographic interferences introduced by the dissolution media and the formulation excipients. In the present work, chromatographic separation of levothyroxine was achieved on an Agilent 1100 Series HPLC with a Waters Nova-pak column (250mm × 3.9mm) using a 0.01 M phosphate buffer (pH 3.0)–methanol (55:45, v/v) in a gradient elution mobile phase at a flow rate of 1.0 mL/min and detection UV wavelength of 225 nm. The injection volume was 800 µL and the column temperature was maintained at 28 °C. The method was validated according to USP Category I requirements. The validation characteristics included accuracy, precision, specificity, linearity, and analytical range. The standard curve was found to have a linear relationship (r2 > 0.99) over the analytical range of 0.08–0.8 µg/mL. Accuracy ranged from 90 to 110% for low quality control (QC) standards and 95 to 105% for medium and high QC standards. Precision was <2% at all QC levels. The method was found to be accurate, precise, selective, and linear for l-T4 over the analytical range. The HPLC method was successfully applied to the analysis of dissolution samples of marketed levothyroxine sodium tablets. PMID:20947276

  4. Autonomous Guidance of Agile Small-scale Rotorcraft

    NASA Technical Reports Server (NTRS)

    Mettler, Bernard; Feron, Eric

    2004-01-01

    This report describes a guidance system for agile vehicles based on a hybrid closed-loop model of the vehicle dynamics. The hybrid model represents the vehicle dynamics through a combination of linear-time-invariant control modes and pre-programmed, finite-duration maneuvers. This particular hybrid structure can be realized through a control system that combines trim controllers and a maneuvering control logic. The former enable precise trajectory tracking, and the latter enables trajectories at the edge of the vehicle capabilities. The closed-loop model is much simpler than the full vehicle equations of motion, yet it can capture a broad range of dynamic behaviors. It also supports a consistent link between the physical layer and the decision-making layer. The trajectory generation was formulated as an optimization problem using mixed-integer-linear-programming. The optimization is solved in a receding horizon fashion. Several techniques to improve the computational tractability were investigate. Simulation experiments using NASA Ames 'R-50 model show that this approach fully exploits the vehicle's agility.

  5. Gamma-ray blazars: The view from AGILE

    NASA Astrophysics Data System (ADS)

    D'Ammando, F.; Bulgarelli, A.; Chen, A. W.; Donnarumma, I.; Giuliani, A.; Longo, F.; Pacciani, L.; Pucella, G.; Striani, E.; Tavani, M.; Vercellone, S.; Vittorini, V.; Covino, S.; Krimm, H. A.; Raiteri, C. M.; Romano, P.; Villata, M.

    2011-07-01

    During the first 3 years of operation the Gamma-Ray Imaging Detector onboard the AGILE satellite detected several blazars in a high γ-ray activity: 3C 279, 3C 454.3, PKS 1510-089, S5 0716+714, 3C 273, W Comae, Mrk 421, PKS 0537-441 and 4C +21.35. Thanks to the rapid dissemination of our alerts, we were able to obtain multiwavelength data from other observatories such as Spitzer, Swift, RXTE, Suzaku, INTEGRAL, MAGIC, VERITAS, and ARGO as well as radio-to-optical coverage by means of the GASP Project of the WEBT and the REM Telescope. This large multifrequency coverage gave us the opportunity to study the variability correlations between the emission at different frequencies and to obtain simultaneous Spectral Energy Distributions of these sources from radio to γ-ray energy bands, investigating the different mechanisms responsible for their emission and uncovering in some cases a more complex behavior with respect to the standard models. We present a review of the most interesting AGILE results on these γ-ray blazars and their multifrequency data.

  6. Discovery of New Gamma-Ray Pulsars with AGILE

    NASA Astrophysics Data System (ADS)

    Pellizzoni, A.; Pilia, M.; Possenti, A.; Chen, A.; Giuliani, A.; Trois, A.; Caraveo, P.; Del Monte, E.; Fornari, F.; Fuschino, F.; Mereghetti, S.; Tavani, M.; Argan, A.; Burgay, M.; Cognard, I.; Corongiu, A.; Costa, E.; D'Amico, N.; De Luca, A.; Esposito, P.; Evangelista, Y.; Feroci, M.; Johnston, S.; Kramer, M.; Longo, F.; Marisaldi, M.; Theureau, G.; Weltevrede, P.; Barbiellini, G.; Boffelli, F.; Bulgarelli, A.; Cattaneo, P. W.; Cocco, V.; D'Ammando, F.; DeParis, G.; Di Cocco, G.; Donnarumma, I.; Fiorini, M.; Froysland, T.; Galli, M.; Gianotti, F.; Labanti, C.; Lapshov, I.; Lazzarotto, F.; Lipari, P.; Mineo, T.; Morselli, A.; Pacciani, L.; Perotti, F.; Piano, G.; Picozza, P.; Prest, M.; Pucella, G.; Rapisarda, M.; Rappoldi, A.; Sabatini, S.; Soffitta, P.; Trifoglio, M.; Vallazza, E.; Vercellone, S.; Vittorini, V.; Zambra, A.; Zanello, D.; Pittori, C.; Verrecchia, F.; Preger, B.; Santolamazza, P.; Giommi, P.; Salotti, L.; Bignami, G. F.

    2009-04-01

    Using gamma-ray data collected by the Astro-rivelatore Gamma ad Immagini LEggero (AGILE) satellite over a period of almost one year (from 2007 July to 2008 June), we searched for pulsed signals from 35 potentially interesting radio pulsars, ordered according to F_{γ}∝ √{\\dot{E}} d^{-2} and for which contemporary or recent radio data were available. AGILE detected three new top-ranking nearby and Vela-like pulsars with good confidence both through timing and spatial analysis. Among the newcomers we find pulsars with very high rotational energy losses, such as the remarkable PSR B1509 - 58 with a magnetic field in excess of 1013 Gauss, and PSR J2229 + 6114 providing a reliable identification for the previously unidentified EGRET source 3EG 2227 + 6122. Moreover, the powerful millisecond pulsar B1821 - 24, in the globular cluster M28, is detected during a fraction of the observations. Four other promising gamma-ray pulsar candidates, among which is the notable J2043 + 2740 with an age in excess of 1 million years, show a possible detection in the timing analysis only and deserve confirmation.

  7. Enhanced detection of Terrestrial Gamma-Ray Flashes by AGILE

    NASA Astrophysics Data System (ADS)

    Marisaldi, M.; Argan, A.; Ursi, A.; Gjesteland, T.; Fuschino, F.; Labanti, C.; Galli, M.; Tavani, M.; Pittori, C.; Verrecchia, F.; D'Amico, F.; Ostgaard, N.; Mereghetti, S.; Campana, R.; Cattaneo, P.; Bulgarelli, A.; Colafrancesco, S.; Dietrich, S.; Longo, F.; Gianotti, F.; Giommi, P.; Rappoldi, A.; Trifoglio, M.; Trois, A.

    2015-12-01

    At the end of March 2015 the onboard configuration of the AGILE satellite was modified in order to disable the veto signal of the anticoincidence shield for the minicalorimeter instrument. The motivation for such a change was the understanding that the dead time induced by the anticoincidence prevented the detection of a large fraction of Terrestrial Gamma-ray Flashes (TGFs), especially the short duration ones. We present here the characteristics of the new TGF sample after several months of stable operations with the new configuration. The configuration change was highly successful resulting in the detection of about 100 TGFs/month, an increase of a factor about 11 in TGFs detection rate with respect to previous configuration. As expected, the largest fraction of the new events has short duration, with a median duration of 80 microseconds. We also obtain a sample of events with simultaneous association, within 100 microseconds, with lightning sferics detected by the World Wide Lightning Location Network (WWLLN), confirming previous results reported by the Fermi mission. Given the high detection rate and the AGILE very low (+/-2.5°) orbital inclination, the new configuration provides the largest TGF detection rate surface density (TGFs / km2 / year) to date, opening space for correlation studies with lightning and atmospheric parameters on short spatial and temporal scales along the equatorial region. Eventually, the events with associated simultaneous WWLLN sferics provide a highly reliable sample to probe the long-standing issue of the TGF maximal energy.

  8. Joint Scheduling and Spectrum Allocation in Wireless Networks with Frequency-Agile Radios

    NASA Astrophysics Data System (ADS)

    Uddin, Mohammad Faisal; Nurujjaman, Mohammad; Assi, Chadi

    We study the benefits of optimal spectrum allocation in a wireless network with frequency agile radios and we present a cross-layer problem formulation for the joint routing and link scheduling under non-uniform spectrum allocation. We present a primal-dual decomposition to provide an exact solution for this complex optimization problem. Given the difficulty associated with such design, we propose a heuristic approach based on simulated annealing to solve the dual sub-problem of the decomposed model. Numerical results revealed that up to 44% improvement in network performance is obtained when variable-width spectrum band allocation is used, as opposed to the best fixed-width spectrum band allocation for larger networks. Numerical results also confirm that the primal-dual decomposition method using simulated annealing to solve the dual sub-problem, substantially reduces the computation time and achieves near optimal solutions.

  9. Development in reliability models and methods

    SciTech Connect

    Vaurio, J.K.

    1983-01-01

    This paper reviews analytical developments in modeling reliability characteristics for components and systems. Modeling involves definition of failure modes, relevant probability and timing parameters for the modes, and derivation of explicit equations for component and system unavailabilities and failure intensities. Some but not all developments to be discussed were carried out within the DOE-sponsored LMFBR safety program.

  10. An updated list of AGILE bright γ-ray sources and their variability in pointing mode

    NASA Astrophysics Data System (ADS)

    Verrecchia, F.; Pittori, C.; Chen, A. W.; Bulgarelli, A.; Tavani, M.; Lucarelli, F.; Giommi, P.; Vercellone, S.; Pellizzoni, A.; Giuliani, A.; Longo, F.; Barbiellini, G.; Trifoglio, M.; Gianotti, F.; Argan, A.; Antonelli, L. A.; Caraveo, P.; Cardillo, M.; Cattaneo, P. W.; Cocco, V.; Colafrancesco, S.; Contessi, T.; Costa, E.; Del Monte, E.; De Paris, G.; Di Cocco, G.; Di Persio, G.; Donnarumma, I.; Evangelista, Y.; Fanari, G.; Feroci, M.; Ferrari, A.; Fiorini, M.; Fornari, F.; Fuschino, F.; Froysland, T.; Frutti, M.; Galli, M.; Labanti, C.; Lapshov, I.; Lazzarotto, F.; Liello, F.; Lipari, P.; Mattaini, E.; Marisaldi, M.; Mastropietro, M.; Mauri, A.; Mauri, F.; Mereghetti, S.; Morelli, E.; Moretti, E.; Morselli, A.; Pacciani, L.; Perotti, F.; Piano, G.; Picozza, P.; Pilia, M.; Pontoni, C.; Porrovecchio, G.; Prest, M.; Primavera, R.; Pucella, G.; Rapisarda, M.; Rappoldi, A.; Rossi, E.; Rubini, A.; Sabatini, S.; Santolamazza, P.; Soffitta, P.; Stellato, S.; Striani, E.; Tamburelli, F.; Traci, A.; Trois, A.; Vallazza, E.; Vittorini, V.; Zanello, D.; Salotti, L.; Valentini, G.

    2013-10-01

    Aims: We present a variability study of a sample of bright γ-ray(30 Mev-50 Gev) sources. This sample is an extension of the first AGILE catalogue of γ-ray sources (1AGL), obtained using the complete set of AGILE observations in pointing mode performed during a 2.3 year period from July 9, 2007 until October 30, 2009. Methods: The dataset of AGILE pointed observations covers a long time interval and its γ-ray data archive is useful for monitoring studies of medium-to-high brightness γ-ray sources. In the analysis reported here, we used data obtained with an improved event filter that covers a wider field of view, on a much larger (about 27.5 months) dataset, integrating data on observation block time scales, which mostly range from a few days to thirty days. Results: The data processing resulted in a better characterized source list than 1AGL was, and includes 54 sources, 7 of which are new high galactic latitude (|BII| ≥ 5) sources, 8 are new sources on the galactic plane, and 20 sources from the previous catalogue with revised positions. Eight 1AGL sources (2 high-latitude and 6 on the galactic plane) were not detected in the final processing either because of low OB exposure and/or due to their position in complex galactic regions. We report the results in a catalogue of all the detections obtained in each single OB, including the variability results for each of these sources. In particular, we found that 12 sources out of 42 or 11 out of 53 are variable, depending on the variability index used, where 42 and 53 are the number of sources for which these indices could be calculated. Seven of the 11 variable sources are blazars, the others are Crab pulsar+nebula, LS I +61°303, Cyg X-3, and 1AGLR J2021+4030. Table 5 is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/558/A137

  11. Kedalion: NASA's Adaptable and Agile Hardware/Software Integration and Test Lab

    NASA Technical Reports Server (NTRS)

    Mangieri, Mark L.; Vice, Jason

    2011-01-01

    NASA fs Kedalion engineering analysis lab at Johnson Space Center is on the forefront of validating and using many contemporary avionics hardware/software development and integration techniques, which represent new paradigms to heritage NASA culture. Kedalion has validated many of the Orion hardware/software engineering techniques borrowed from the adjacent commercial aircraft avionics solution space, with the intention to build upon such techniques to better align with today fs aerospace market. Using agile techniques, commercial products, early rapid prototyping, in-house expertise and tools, and customer collaboration, Kedalion has demonstrated that cost effective contemporary paradigms hold the promise to serve future NASA endeavors within a diverse range of system domains. Kedalion provides a readily adaptable solution for medium/large scale integration projects. The Kedalion lab is currently serving as an in-line resource for the project and the Multipurpose Crew Vehicle (MPCV) program.

  12. Child Development in Developing Countries: Introduction and Methods

    PubMed Central

    Bornstein, Marc H.; Britto, Pia Rebello; Nonoyama-Tarumi, Yuko; Ota, Yumiko; Petrovic, Oliver; Putnick, Diane L.

    2011-01-01

    The Multiple Indicator Cluster Survey (MICS) is a nationally representative, internationally comparable household survey implemented to examine protective and risk factors of child development in developing countries around the world. This Introduction describes the conceptual framework, nature of the MICS3, and general analytic plan of articles in this Special Section. The articles that follow describe the situations of children with successive foci on nutrition, parenting, discipline and violence, and the home environment addressing two common questions: How do developing and underresearched countries in the world vary with respect to these central indicators of children's development? and How do key indicators of national development relate to child development in each of these substantive areas? The Special Section concludes with policy implications from the international findings. PMID:22277004

  13. Method Development for Analysis of Aspirin Tablets.

    ERIC Educational Resources Information Center

    Street, Kenneth W., Jr.

    1988-01-01

    Develops a lab experiment for introductory instrumental analysis that requires interference studies and optimizing of conditions. Notes the analysis of the aspirin is by visible spectrophotometric assay. Gives experimental details and discussion. (MVL)

  14. Development of advanced acreage estimation methods

    NASA Technical Reports Server (NTRS)

    Guseman, L. F., Jr. (Principal Investigator)

    1980-01-01

    The use of the AMOEBA clustering/classification algorithm was investigated as a basis for both a color display generation technique and maximum likelihood proportion estimation procedure. An approach to analyzing large data reduction systems was formulated and an exploratory empirical study of spatial correlation in LANDSAT data was also carried out. Topics addressed include: (1) development of multiimage color images; (2) spectral spatial classification algorithm development; (3) spatial correlation studies; and (4) evaluation of data systems.

  15. Child Development in Developing Countries: Introduction and Methods

    ERIC Educational Resources Information Center

    Bornstein, Marc H.; Britto, Pia Rebello; Nonoyama-Tarumi, Yuko; Ota, Yumiko; Petrovic, Oliver; Putnick, Diane L.

    2012-01-01

    The Multiple Indicator Cluster Survey (MICS) is a nationally representative, internationally comparable household survey implemented to examine protective and risk factors of child development in developing countries around the world. This introduction describes the conceptual framework, nature of the MICS3, and general analytic plan of articles…

  16. Micro-milling process improvement using an agile pulse-shaping fiber laser

    NASA Astrophysics Data System (ADS)

    Gay, David; Cournoyer, Alain; Deladurantaye, Pascal; Briand, Martin; Roy, Vincent; Labranche, Bruno; Levesque, Marc; Taillon, Y.

    2009-06-01

    We demonstrate the usefulness of INO's pulse-shaping fiber laser platform to rapidly develop complex laser micromachining processes. The versatility of such laser sources allows for straightforward control of the emitting energy envelop on the nanosecond timescale to create multi-amplitude level pulses and/or multi-pulse regimes. The pulses are amplified in an amplifier chain in a MOPA configuration that delivers output energy per pulse up to 60 μJ at 1064 nm at a repetition rate of 200 kHz with excellent beam quality (M2 < 1.1) and narrow line widths suitable for efficient frequency conversion. Also, their pulse-on-demand and pulse-to-pulse shape selection capability at high repetition rates makes those agile laser sources suitable for the implementation of high-throughput complex laser processing. Micro-milling experiments were carried out on two metals, aluminum and stainless steel, having very different thermal properties. For aluminum, our results show that the material removal efficiency depends strongly on the pulse shape, especially near the ablation threshold, and can be maximized to develop efficient laser micro-milling processes. But, the material removal efficiency is not always correlated with a good surface quality. However, the roughness of the milled surface can be improved by removing a few layers of material using another type of pulse shape. The agility of INO's fiber laser enables the implementation of a fast laser process including two steps employing different pulse characteristics for maximizing the material removal rate and obtaining a good surface quality at the same time. A comparison of material removal efficiency with stainless steel, well known to be difficult to mill on the micron scale, is also presented.

  17. 24 CFR 941.102 - Development methods and funding.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... site. The PHA awards a construction contract in accordance with 24 CFR part 85. The contractor receives... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Development methods and funding... URBAN DEVELOPMENT PUBLIC HOUSING DEVELOPMENT General § 941.102 Development methods and funding....

  18. 24 CFR 941.102 - Development methods and funding.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... site. The PHA awards a construction contract in accordance with 24 CFR part 85. The contractor receives... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Development methods and funding... URBAN DEVELOPMENT PUBLIC HOUSING DEVELOPMENT General § 941.102 Development methods and funding....

  19. 24 CFR 941.102 - Development methods and funding.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... site. The PHA awards a construction contract in accordance with 24 CFR part 85. The contractor receives... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Development methods and funding... URBAN DEVELOPMENT PUBLIC HOUSING DEVELOPMENT General § 941.102 Development methods and funding....

  20. Using Qualitative Methods to Inform Scale Development

    ERIC Educational Resources Information Center

    Rowan, Noell; Wulff, Dan

    2007-01-01

    This article describes the process by which one study utilized qualitative methods to create items for a multi dimensional scale to measure twelve step program affiliation. The process included interviewing fourteen addicted persons while in twelve step focused treatment about specific pros (things they like or would miss out on by not being…

  1. Development of ultrasonic methods for hemodynamic measurements

    NASA Technical Reports Server (NTRS)

    Histand, M. B.; Miller, C. W.; Wells, M. K.; Mcleod, F. D.; Greene, E. R.; Winter, D.

    1975-01-01

    A transcutanous method to measure instantaneous mean blood flow in peripheral arteries of the human body was defined. Transcutanous and implanted cuff ultrasound velocity measurements were evaluated, and the accuracies of velocity, flow, and diameter measurements were assessed for steady flow. Performance criteria were established for the pulsed Doppler velocity meter (PUDVM), and performance tests were conducted. Several improvements are suggested.

  2. DEVELOPMENT AND EVALUATION OF COMPOSITE RECEPTOR METHODS

    EPA Science Inventory

    A composite receptor method for PM-10 apportionment was evaluated to determine the stability of its solutions and to devise cost-effective measurement strategies. Aerosol samples used in the evaluation were collected during summer, 1982, by dichotomous samplers at three sites in ...

  3. Methods for generating hydroelectric power development alternatives

    SciTech Connect

    Chang, Shoou-yuh; Liaw, Shu-liang; Sale, M.J.; Railsback, S.F.

    1989-01-01

    Hydropower development on large rivers can result in a number of environmental impacts, including potential reductions in dissolved oxygen (DO) concentrations. This study presents a methodology for generating different hydropower development alternatives for evaluation. This methodology employs a Streeter-Phelps model to simulate DO, and the Bounded Implicit Enumeration algorithm to solve an optimization model formulated to maximize hydroelectric energy production subject to acceptable DO limits. The upper Ohio River basin was used to illustrate the use and characteristics of the methodology. The results indicate that several alternatives which meet the specified DO constraints can be generated efficiently, meeting both power and environmental objectives. 17 refs., 2 figs., 1 tab.

  4. Development of advanced acreage estimation methods

    NASA Technical Reports Server (NTRS)

    Guseman, L. F., Jr. (Principal Investigator)

    1982-01-01

    The development of an accurate and efficient algorithm for analyzing the structure of MSS data, the application of the Akaiki information criterion to mixture models, and a research plan to delineate some of the technical issues and associated tasks in the area of rice scene radiation characterization are discussed. The AMOEBA clustering algorithm is refined and documented.

  5. A Method for Developing a Nutrient Guide.

    ERIC Educational Resources Information Center

    Gillespie, Ardyth H.; Roderuck, Charlotte E.

    1982-01-01

    This paper proposes a new approach to developing a tool for teaching nutrition and food selection. It allows adjustments as new information becomes available and takes into account both dietary recommendations and food composition. Steps involve nutrient composition; nutrient density; and ratings for fat, cholesterol, and sodium. (Author/CT)

  6. An Unbalance Adjustment Method for Development Indicators

    ERIC Educational Resources Information Center

    Tarabusi, Enrico Casadio; Guarini, Giulio

    2013-01-01

    This paper analyzes some aggregation aspects of the procedure for constructing a composite index on a multidimensional socio-economic phenomenon such as development, the main focus being on the unbalance among individual dimensions. First a theoretical framework is set up for the unbalance adjustment of the index. Then an aggregation function is…

  7. Recommendations for Developing Alternative Test Methods for Developmental Neurotoxicity

    EPA Science Inventory

    There is great interest in developing alternative methods for developmental neurotoxicity testing (DNT) that are cost-efficient, use fewer animals and are based on current scientific knowledge of the developing nervous system. Alternative methods will require demonstration of the...

  8. Current status of fluoride volatility method development

    SciTech Connect

    Uhlir, J.; Marecek, M.; Skarohlid, J.

    2013-07-01

    The Fluoride Volatility Method is based on a separation process, which comes out from the specific property of uranium, neptunium and plutonium to form volatile hexafluorides whereas most of fission products (mainly lanthanides) and higher transplutonium elements (americium, curium) present in irradiated fuel form nonvolatile tri-fluorides. Fluoride Volatility Method itself is based on direct fluorination of the spent fuel, but before the fluorination step, the removal of cladding material and subsequent transformation of the fuel into a powdered form with a suitable grain size have to be done. The fluorination is made with fluorine gas in a flame fluorination reactor, where the volatile fluorides (mostly UF{sub 6}) are separated from the non-volatile ones (trivalent minor actinides and majority of fission products). The subsequent operations necessary for partitioning of volatile fluorides are the condensation and evaporation of volatile fluorides, the thermal decomposition of PuF{sub 6} and the finally distillation and sorption used for the purification of uranium product. The Fluoride Volatility Method is considered to be a promising advanced pyrochemical reprocessing technology, which can mainly be used for the reprocessing of oxide spent fuels coming from future GEN IV fast reactors.

  9. The frequency-agile radar: A multifunctional approach to remote sensing of the ionosphere

    NASA Astrophysics Data System (ADS)

    Tsunoda, R. T.; Livingston, R. C.; Buonocore, J. J.; McKinley, A. V.

    1995-09-01

    We introduce a new kind of diagnostic sensor that combines multifunctional measurement capabilities for ionospheric research. Multifunctionality is realized through agility in frequency selection over an extended band (1.5 to 50 MHz), system modularity, complete system control by software written in C, and a user-friendly computer interface. This sensor, which we call the frequency-agile radar (FAR), incorporates dual radar channels and an arbitrary waveform synthesizer that allows creative design of sophisticated waveforms as a means of increasing its sensitivity to weak signals while minimizing loss in radar resolution. The sensitivity of the FAR is determined by two sets of power amplifier modules: four 4-kW solid-state broadband amplifiers, and four 30-kW vacuum tube amplifiers. FAR control is by an AT-bus personal computer with on-line processing by a programmable array processor. The FAR does not simply house the separate functions of most radio sensors in use today, it provides convenient and flexible access to those functions as elements to be used in any combination. Some of the first new results obtained with the FAR during recent field campaigns are presented to illustrate its versatility. These include (1) the first detection of anomalous high-frequency (HF) reflections from a barium ion cloud, (2) the first evidence of unexpectedly large drifts and a shear north of the equatorial electrojet, (3) the first HF radar signature of a developing equatorial plasma bubble, and (4) the first measurements by a portable radar of altitude-extended, quasi-periodic backscatter from midlatitude sporadic E. We also mention the potential of the FAR for atmospheric remote sensing.

  10. Design studies for a spectrally agile staring sensor /SASS/ system

    NASA Astrophysics Data System (ADS)

    Kollodge, M. A.; Cox, J. A.; Marshall, W. C.; Solstad, R. G.; Steadman, S. S.

    1981-01-01

    The operation of the Spectrally Agile Staring Sensor (SASS) involves the employment of a telescope system which uses variable spectral band information to detect and identify moving IR sources against the background radiance of the earth. A description is presented of SASS simulation studies. A signal-to-noise ratio (SNR) expression used as a measure of system performance is considered. Attention is given to the target trajectory generator, a target signature model, a background and atmospheric model, a Dual Tunable Fabry-Perot (DTFP) optical filter model, problems of out-of-band leakage transmission, a Focal Plane Array (FPA)/spot convolution model, SNR improvement with high filter transmission efficiency, system performance vs DTFP optical filter parameters, and system performance vs atmospheric conditions.

  11. An Adaptive, Agile, Reconfigurable Photonic System for Handling Analog Signals

    NASA Astrophysics Data System (ADS)

    Middleton, C.; DeSalvo, R.; Escalera, N.

    2014-09-01

    Photonic techniques can be applied to microwave and millimeter wave transmission and signal processing challenges, including signal transport, distribution, filtering, and up- and down-conversion. We present measured performance results for a wideband photonic-assisted frequency converter with 4 GHz instantaneous bandwidth and full spectral coverage up to 45 GHz. The photonic-assisted converter is applicable for both ground and space applications. We show the system performance in a ground station application, in which high frequency analog signals were transported over a moderate distance and down-converted directly into a digitizing receiver. We also describe our progress in the packaging and space qualification of the photonic system, and discuss the next steps toward higher TRL. The photonic system provides an adaptive, agile, reconfigurable backbone for handling analog signals, with performance superior to existing microwave systems.

  12. Software Product Line Engineering Approach for Enhancing Agile Methodologies

    NASA Astrophysics Data System (ADS)

    Martinez, Jabier; Diaz, Jessica; Perez, Jennifer; Garbajosa, Juan

    One of the main principles of Agile methodologies consists in the early and continuous delivery of valuable software by short time-framed iterations. After each iteration, a working product is delivered according to the requirements defined at the beginning of the iteration. Testing tools facilitate the task of checking if the system provides the expected behavior according to the specified requirements. However, since testing tools need to be adapted in order to test new working products in each iteration, a significant effort has to be invested. This work presents a Software Product Line Engineering (SPLE) approach that allows flexibility in the adaption of testing tools with the working products in an iterative way. A case study is also presented using PLUM (Product Line Unified Modeller) as the tool suite for SPL implementation and management.

  13. SAMPLE (Sandia agile MEMS prototyping, layout tools, and education)

    NASA Astrophysics Data System (ADS)

    Davies, Brady R.; Craig Barron, Carole; Sniegowski, Jeffry J.; Rodgers, M. Steven

    1997-09-01

    The SAMPLE (Sandia agile MEMS prototyping, layout tools, and education) service makes Sandia's state-of-the-art surface micromachining fabrication process, known as SUMMiT, available to U.S. industry for the first time. The service provides a short course and customized computer-aided design (CAD) tools to assist customers in designing micromachine prototypes to be fabricated in SUMMiT. Frequent small-scale manufacturing runs then provide SAMPLE designers with hundreds of sophisticated MEMS (microelectromechanical systems) chips. SUMMiT (Sandia ultra-planar, multi-level MEMS technology) offers unique surface-micromachining capabilities, including four levels of polycrystalline silicon (including the ground layer), flanged hubs, substrate contacts, one-micron design rules, and chemical-mechanical polishing (CMP) planarization. This paper describes the SUMMiT process, design tools, and other information relevant to the SAMPLE service and SUMMiT process.

  14. SAMPLE (Sandia Agile MEMS Prototyping, Layout tools, and Education)

    SciTech Connect

    Davies, B.R.; Barron, C.C.; Sniegowski, J.J.; Rodgers, M.S.

    1997-08-01

    The SAMPLE (Sandia Agile MEMS Protyping, Layout tools, and Education) service makes Sandia`s state-of-the-art surface-micromachining fabrication process, known as SUMMiT, available to US industry for the first time. The service provides a short cause and customized computer-aided design (CAD) tools to assist customers in designing micromachine prototypes to be fabricated in SUMMiT. Frequent small-scale manufacturing runs then provide SAMPLE designers with hundreds of sophisticated MEMS (MicroElectroMechanical Systems) chips. SUMMiT (Sandia Ultra-planar, Multi-level MEMS Technology) offers unique surface-micromachining capabilities, including four levels of polycrystalline silicon (including the ground layer), flanged hubs, substrate contacts, one-micron design rules, and chemical-mechanical polishing (CMP) planarization. This paper describes the SUMMiT process, design tools, and other information relevant to the SAMPLE service and SUMMiT process.

  15. Frequency Agile Transceiver for Advanced Vehicle Data Links

    NASA Technical Reports Server (NTRS)

    Freudinger, Lawrence C.; Macias, Filiberto; Cornelius, Harold

    2009-01-01

    Emerging and next-generation test instrumentation increasingly relies on network communication to manage complex and dynamic test scenarios, particularly for uninhabited autonomous systems. Adapting wireless communication infrastructure to accommodate challenging testing needs can benefit from reconfigurable radio technology. Frequency agility is one characteristic of reconfigurable radios that to date has seen only limited progress toward programmability. This paper overviews an ongoing project to validate a promising chipset that performs conversion of RF signals directly into digital data for the wireless receiver and, for the transmitter, converts digital data into RF signals. The Software Configurable Multichannel Transceiver (SCMT) enables four transmitters and four receivers in a single unit, programmable for any frequency band between 1 MHz and 6 GHz.

  16. AGILE follow-up of the neutrino ICECUBE-160731 event

    NASA Astrophysics Data System (ADS)

    Lucarelli, F.; Pittori, C.; Verrecchia, F.; Piano, G.; Munar-Adrover, P.; Bulgarelli, A.; Fioretti, V.; Zoli, A.; Tavani, M.; Donnarumma, I.; Vercellone, S.; Minervini, G.; Striani, E.; Cardillo, M.; Gianotti, F.; Trifoglio, M.; Giuliani, A.; Mereghetti, S.; Caraveo, P.; Perotti, F.; Chen, A.; Argan, A.; Costa, E.; Del Monte, E.; Evangelista, Y.; Feroci, M.; Lazzarotto, F.; Lapshov, I.; Pacciani, L.; Soffitta, P.; Sabatini, S.; Vittorini, V.; Pucella, G.; Rapisarda, M.; Di Cocco, G.; Fuschino, F.; Galli, M.; Labanti, C.; Marisaldi, M.; Pellizzoni, A.; Pilia, M.; Trois, A.; Barbiellini, G.; Vallazza, E.; Longo, F.; Morselli, A.; Picozza, P.; Prest, M.; Lipari, P.; Zanello, D.; Cattaneo, P. W.; Rappoldi, A.; Colafrancesco, S.; Parmiggiani, N.; Ferrari, A.; Antonelli, A.; Giommi, P.; Salotti, L.; Valentini, G.; D'Amico, F.

    2016-08-01

    Following the GCN notice posted by the ICECUBE Collaboration on July 31, 2016, reporting the detection at T0=16/07/31 01:55:04 UT of a very high energy neutrino with reconstructed arrival direction pointing at RA, DEC (J2000)=(214.5440, -0.3347 [deg]) with a 90% containement radius of 45.00 arcmin (stat+sys), we searched for transient gamma-ray emission in the AGILE data above 100 MeV. Integrating over the 48 hours from 2016-07-29 02:00 UT to 2016-07-31 02:00 UT a maximum likelihood analysis yields a possible detection at a significance level of about 3 sigma with a flux F(E > 100 MeV)=(1.5 +/- 0.7)x 10^-06 ph/cm^2/s within the GCN/AMON_ICECUBE_HESE notice error region.

  17. Pulsar timing and the Fermi and AGILE missions

    NASA Astrophysics Data System (ADS)

    Johnston, Simon; Possenti, Andrea; Manchester, Dick; Hobbs, George; Keith, Michael; Romani, Roger W.; Thompson, David J.; Thorsett, Stephen; Roberts, Mallory; Weltevrede, Patrick

    2010-10-01

    We request time to observe 170 pulsars on a regular basis in order to provide accurate ephemerides necessary for the detection of gamma-ray pulsars with the Fermi and AGILE satellites. The main science goals are to increase the number of known gamma-ray pulsars (both radio loud and radio quiet), to determine accurate pulse profiles, to characterise their high energy spectra and phase resolved spectroscopy of the brightest pulsars. In the radio, the observations will also allow us to find glitches, characterise timing noise, investigate dispersion and rotation measure variability and enhance our knowledge of single pulse phenomenology. To date, we are (co-)authors on 27 papers arising from the collaboration and P574 data. The data have contributed to the PhD theses of Lucas Guillemot and Damien Parent from the Bordeaux Fermi group (submitted mid 2009) and Kyle Watters from Stanford.

  18. Pulsar timing and the Fermi and AGILE missions

    NASA Astrophysics Data System (ADS)

    Johnston, Simon; Possenti, Andrea; Manchester, Dick; Hobbs, George; Keith, Michael; Romani, Roger W.; Thompson, David J.; Thorsett, Stephen; Roberts, Mallory; Weltevrede, Patrick

    2010-04-01

    We request time to observe 170 pulsars on a regular basis in order to provide accurate ephemerides necessary for the detection of gamma-ray pulsars with the Fermi and AGILE satellites. The main science goals are to increase the number of known gamma-ray pulsars (both radio loud and radio quiet), to determine accurate pulse profiles, to characterise their high energy spectra and phase resolved spectroscopy of the brightest pulsars. In the radio, the observations will also allow us to find glitches, characterise timing noise, investigate dispersion and rotation measure variability and enhance our knowledge of single pulse phenomenology. To date, we are (co-)authors on 20 papers arising from the collaboration and P574 data. The data have contributed to the PhD theses of Lucas Guillemot and Damien Parent from the Bordeaux Fermi group (submitted mid 2009).

  19. Pulsar Timing and the Fermi and AGILE missions

    NASA Astrophysics Data System (ADS)

    Shannon, Ryan; Possenti, Andrea; Manchester, Dick; Johnston, Simon; Hobbs, George; Keith, Michael; Romani, Roger W.; Thompson, David J.; Roberts, Mallory; Weltevrede, Patrick; Kerr, Matthew; Petroff, Emily; Brook, Paul

    2013-10-01

    We request time to observe 170 pulsars on a regular basis in order to provide accurate ephemerides necessary for the detection of gamma-ray pulsars with the Fermi and AGILE satellites. The main science goals are to increase the number of known gamma-ray pulsars (both radio loud and radio quiet), to determine accurate pulse profiles, to characterise their high energy spectra and phase resolved spectroscopy of the brightest pulsars. In the radio, the observations will also allow us to find glitches, characterise timing noise, investigate dispersion and rotation measure variability and enhance our knowledge of single pulse phenomenology. To date, we are (co-)authors on 43 papers arising from the collaboration and P574 data. The data have contributed to the PhD theses of Lucas Guillemot and Damien Parent from the Bordeaux Fermi group and Kyle Watters from Stanford. Currently five students have active projects using the radio datasets.

  20. Pulsar Timing and the Fermi and AGILE missions

    NASA Astrophysics Data System (ADS)

    Shannon, Ryan; Possenti, Andrea; Manchester, Dick; Johnston, Simon; Hobbs, George; Keith, Michael; Romani, Roger W.; Thompson, David J.; Thorsett, Stephen; Roberts, Mallory; Weltevrede, Patrick

    2011-04-01

    We request time to observe 170 pulsars on a regular basis in order to provide accurate ephemerides necessary for the detection of gamma-ray pulsars with the Fermi and AGILE satellites. The main science goals are to increase the number of known gamma-ray pulsars (both radio loud and radio quiet), to determine accurate pulse profiles, to characterise their high energy spectra and phase resolved spectroscopy of the brightest pulsars. In the radio, the observations will also allow us to find glitches, characterise timing noise, investigate dispersion and rotation measure variability and enhance our knowledge of single pulse phenomenology. To date, we are (co-)authors on 27 papers arising from the collaboration and P574 data. The data have contributed to the PhD theses of Lucas Guillemot and Damien Parent from the Bordeaux Fermi group (submitted mid 2009) and Kyle Watters from Stanford.

  1. Pulsar Timing and the Fermi and AGILE missions

    NASA Astrophysics Data System (ADS)

    Shannon, Ryan; Possenti, Andrea; Manchester, Dick; Johnston, Simon; Hobbs, George; Keith, Michael; Romani, Roger W.; Thompson, David J.; Thorsett, Stephen; Roberts, Mallory; Weltevrede, Patrick

    2011-10-01

    We request time to observe 170 pulsars on a regular basis in order to provide accurate ephemerides necessary for the detection of gamma-ray pulsars with the Fermi and AGILE satellites. The main science goals are to increase the number of known gamma-ray pulsars (both radio loud and radio quiet), to determine accurate pulse profiles, to characterise their high energy spectra and phase resolved spectroscopy of the brightest pulsars. In the radio, the observations will also allow us to find glitches, characterise timing noise, investigate dispersion and rotation measure variability and enhance our knowledge of single pulse phenomenology. To date, we are (co-)authors on 27 papers arising from the collaboration and P574 data. The data have contributed to the PhD theses of Lucas Guillemot and Damien Parent from the Bordeaux Fermi group (submitted mid 2009) and Kyle Watters from Stanford.

  2. Pulsar Timing and the Fermi and AGILE missions

    NASA Astrophysics Data System (ADS)

    Shannon, Ryan; Possenti, Andrea; Manchester, Dick; Johnston, Simon; Hobbs, George; Keith, Michael; Romani, Roger W.; Thompson, David J.; Thorsett, Stephen; Roberts, Mallory; Weltevrede, Patrick

    2012-04-01

    We request time to observe 170 pulsars on a regular basis in order to provide accurate ephemerides necessary for the detection of gamma-ray pulsars with the Fermi and AGILE satellites. The main science goals are to increase the number of known gamma-ray pulsars (both radio loud and radio quiet), to determine accurate pulse profiles, to characterise their high energy spectra and phase resolved spectroscopy of the brightest pulsars. In the radio, the observations will also allow us to find glitches, characterise timing noise, investigate dispersion and rotation measure variability and enhance our knowledge of single pulse phenomenology. To date, we are (co-)authors on 27 papers arising from the collaboration and P574 data. The data have contributed to the PhD theses of Lucas Guillemot and Damien Parent from the Bordeaux Fermi group (submitted mid 2009) and Kyle Watters from Stanford.

  3. Pulsar Timing and the Fermi and AGILE missions

    NASA Astrophysics Data System (ADS)

    Shannon, Ryan; Possenti, Andrea; Manchester, Dick; Johnston, Simon; Hobbs, George; Keith, Michael; Romani, Roger W.; Thompson, David J.; Thorsett, Stephen; Roberts, Mallory; Weltevrede, Patrick

    2012-10-01

    We request time to observe 170 pulsars on a regular basis in order to provide accurate ephemerides necessary for the detection of gamma-ray pulsars with the Fermi and AGILE satellites. The main science goals are to increase the number of known gamma-ray pulsars (both radio loud and radio quiet), to determine accurate pulse profiles, to characterise their high energy spectra and phase resolved spectroscopy of the brightest pulsars. In the radio, the observations will also allow us to find glitches, characterise timing noise, investigate dispersion and rotation measure variability and enhance our knowledge of single pulse phenomenology. To date, we are (co-)authors on 37 papers arising from the collaboration and P574 data. The data have contributed to the PhD theses of Lucas Guillemot and Damien Parent from the Bordeaux Fermi group and Kyle Watters from Stanford.

  4. Pulsar Timing and the Fermi and AGILE missions

    NASA Astrophysics Data System (ADS)

    Shannon, Ryan; Possenti, Andrea; Manchester, Dick; Johnston, Simon; Hobbs, George; Keith, Michael; Romani, Roger W.; Thompson, David J.; Roberts, Mallory; Weltevrede, Patrick; Brook, Paul

    2013-04-01

    We request time to observe 170 pulsars on a regular basis in order to provide accurate ephemerides necessary for the detection of gamma-ray pulsars with the Fermi and AGILE satellites. The main science goals are to increase the number of known gamma-ray pulsars (both radio loud and radio quiet), to determine accurate pulse profiles, to characterise their high energy spectra and phase resolved spectroscopy of the brightest pulsars. In the radio, the observations will also allow us to find glitches, characterise timing noise, investigate dispersion and rotation measure variability and enhance our knowledge of single pulse phenomenology. To date, we are (co-)authors on 37 papers arising from the collaboration and P574 data. The data have contributed to the PhD theses of Lucas Guillemot and Damien Parent from the Bordeaux Fermi group and Kyle Watters from Stanford. Currently for students have active projects using the radio datasets.

  5. Enhanced detection of terrestrial gamma-ray flashes by AGILE

    NASA Astrophysics Data System (ADS)

    Marisaldi, M.; Argan, A.; Ursi, A.; Gjesteland, T.; Fuschino, F.; Labanti, C.; Galli, M.; Tavani, M.; Pittori, C.; Verrecchia, F.; D'Amico, F.; Østgaard, N.; Mereghetti, S.; Campana, R.; Cattaneo, P. W.; Bulgarelli, A.; Colafrancesco, S.; Dietrich, S.; Longo, F.; Gianotti, F.; Giommi, P.; Rappoldi, A.; Trifoglio, M.; Trois, A.

    2015-11-01

    At the end of March 2015 the onboard software configuration of the Astrorivelatore Gamma a Immagini Leggero (AGILE) satellite was modified in order to disable the veto signal of the anticoincidence shield for the minicalorimeter instrument. The motivation for such a change was the understanding that the dead time induced by the anticoincidence prevented the detection of a large fraction of Terrestrial Gamma-Ray Flashes (TGFs). The configuration change was highly successful resulting in an increase of one order of magnitude in TGF detection rate. As expected, the largest fraction of the new events has short duration (<100 μs), and part of them has simultaneous association with lightning sferics detected by the World Wide Lightning Location Network. The new configuration provides the largest TGF detection rate surface density (TGFs/km2/yr) to date, opening prospects for improved correlation studies with lightning and atmospheric parameters on short spatial and temporal scales along the equatorial region.

  6. Developing Automated Methods of Waste Sorting

    SciTech Connect

    Shurtliff, Rodney Marvin

    2002-08-01

    The U.S. Department of Energy (DOE) analyzed the need complex-wide for remote and automated technologies as they relate to the treatment and disposal of mixed wastes. This analysis revealed that several DOE sites need the capability to open drums containing waste, visually inspect and sort the contents, and finally repackage the containers that are acceptable at a waste disposal facility such as the Waste Isolation Pilot Plant (WIPP) in New Mexico. Conditioning contaminated waste so that it is compatible with the WIPP criteria for storage is an arduous task whether the waste is contact handled (waste having radioactivity levels below 200 mrem/hr) or remote handled. Currently, WIPP non-compliant items are removed from the waste stream manually, at a rate of about one 55-gallon drum per day. Issues relating to contamination-based health hazards as well as repetitive motion health hazards are steering industry towards a more user-friendly, method of conditioning or sorting waste.

  7. 24 CFR 941.102 - Development methods and funding.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Development methods and funding. 941.102 Section 941.102 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT PUBLIC HOUSING...

  8. A Block-Matrix Method for Course Development

    ERIC Educational Resources Information Center

    Greenaway, John

    1977-01-01

    Describes the block-matrix method, a technique used to develop new training programs (commonly involving educational program developers and community representatives). Two examples of the block-matrix application and supplementary diagrams are included. It is noted that this method has been used successfully in the development of new courses for…

  9. Cavity-Enhanced Frequency-Agile Rapid Scanning (fars) Spectroscopy: Measurement Principles

    NASA Astrophysics Data System (ADS)

    Hodges, Joseph T.; Long, David A.; Truong, Gar-Wing; Douglass, Kevin O.; Maxwell, Stephen E.; Zee, Roger Van; Plusquellic, David F.

    2013-06-01

    We present the principles of frequency-agile, rapid scanning (FARS) spectroscopy, a new technique for high-bandwidth, cavity-enhanced, laser absorption measurements. This method enables a visible or near-infrared probe laser beam to be frequency tuned over several tens of GHz using a microwave source, a waveguide phase modulator and a filter cavity. For the types of cavity-enhanced methods discussed here, the optical resonator itself is used to select a single sideband of the modulated laser spectrum, obviating the need for a separate filter cavity. FARS offers several important advantages over conventional cw laser tuning methods based on thermal or mechanical methods. These include, high speed tuning with sub-ms switching times, the ability to select arbitrary frequency steps or chirp rates, and the realization of a spectrum detuning axis with sub-kHz level precision. We discuss how FARS can be applied to cavity ring-down spectroscopy and other cavity-enhanced methods to enable rapid and accurate measurements of line parameters and to give noise-equivalent absorption coefficients at the 10^{-12} cm^{-1} Hz^{-1/2} level.

  10. Geometric simulation analysis of multi-band mosaic imaging from the same orbit by agile satellites

    NASA Astrophysics Data System (ADS)

    Xu, Yue; Chen, Jinwei; Chen, Yueting; Xu, Zhihai; Feng, Huajun; Li, Qi

    2015-08-01

    This paper establishes a geometric model of multi-band mosaic imaging from the same orbit by agile satellites, and introduces a self-write simulation software. Geometric parameters of each band are calculated based on the attitude control ability of the satellite and the mission requirements. Considering the different ground resolution and the imaging angle of each band, two new concepts, Gradient Entropy and Structure Similarity Parameter are presented. These two values are used to evaluate the change of image quality caused by agility, and help to estimate the effect of the mission. By building the geometric model and calculating the agile information with the program, we propose a new approach of forward analysis of agile imaging, which helps users evaluate the image degradation.

  11. Renewed Gamma-Ray Emission from the blazar PKS 1510-089 Detected by AGILE

    NASA Astrophysics Data System (ADS)

    Munar-Adrover, P.; Pittori, C.; Bulgarelli, A.; Lucarelli, F.; Verrecchia, F.; Piano, G.; Fioretti, V.; Zoli, A.; Tavani, M.; Vercellone, S.; Minervini, G.; Striani, E.; Cardillo, M.; Gianotti, F.; Trifoglio, M.; Giuliani, A.; Mereghetti, S.; Caraveo, P.; Perotti, F.; Chen, A.; Argan, A.; Costa, E.; Del Monte, E.; Donnarumma, I.; Evangelista, Y.; Feroci, M.; Lazzarotto, F.; Lapshov, I.; Pacciani, L.; Soffitta, P.; Sabatini, S.; Vittorini, V.; Pucella, G.; Rapisarda, M.; Di Cocco, G.; Fuschino, F.; Galli, M.; Labanti, C.; Marisaldi, M.; Pellizzoni, A.; Pilia, M.; Trois, A.; Barbiellini, G.; Vallazza, E.; Longo, F.; Morselli, A.; Picozza, P.; Prest, M.; Lipari, P.; Zanello, D.; Cattaneo, P. W.; Rappoldi, A.; Colafrancesco, S.; Parmiggiani, N.; Ferrari, A.; Antonelli, A.; Giommi, P.; Salotti, L.; Valentini, G.; D'Amico, F.

    2016-09-01

    AGILE is currently detecting enhanced gamma-ray emission above 100 MeV from a source which position is consistent with the blazar PKS 1510-089. (the last activity of this source was reported in ATel #9350).

  12. Multi-Directional Sprint Training Improves Change-Of-Direction Speed and Reactive Agility in Young Highly Trained Soccer Players.

    PubMed

    Born, Dennis-Peter; Zinner, Christoph; Düking, Peter; Sperlich, Billy

    2016-06-01

    may result in specific adaptations that improve COD speed and reactive agility.The Speedcourt could serve as a valuable method to design and individualize specific conditioning drills for young highly-trained soccer players. PMID:27274670

  13. Multi-Directional Sprint Training Improves Change-Of-Direction Speed and Reactive Agility in Young Highly Trained Soccer Players

    PubMed Central

    Born, Dennis-Peter; Zinner, Christoph; Düking, Peter; Sperlich, Billy

    2016-01-01

    , which may result in specific adaptations that improve COD speed and reactive agility. The Speedcourt could serve as a valuable method to design and individualize specific conditioning drills for young highly-trained soccer players. PMID:27274670

  14. Strength and agility training in adolescents with Down syndrome: a randomized controlled trial.

    PubMed

    Lin, Hsiu-Ching; Wuang, Yee-Pay

    2012-01-01

    The purpose of this study was to investigate the effects of a proposed strength and agility training program of adolescents with Down syndrome. Ninety-two adolescents were recruited and evenly randomized to two intervention groups (exercise group vs. control group). The mean age for the exercise and the control group was 10.6±3.2 and 11.2±3.5 respectively. The exercise training program consisted of a 5-min treadmill exercise and one 20-min virtual-reality based activity administered three times a week for 6 weeks. Pre- and post-test measures were taken for muscle strength and agility performance. The measured muscle included hip extensor, hip flexor, knee extensor, knee flexors, hip abductors, and ankle plantarflexor. A handheld dynamometer was used to measure the lower extremities muscle strength, and agility performance was assessed by the strength and agility subtests of the Bruininks-Oseretsky Test of Motor Proficiency-Second Edition. The exercise group had significant improvements in agility (p=0.02, d=0.80) and muscle strength of all muscle group (all p's<0.05, d=0.51-0.89) assessed in comparison to the control group after the 6-week intervention. Knee muscle groups including both flexors and extensors had the greatest gains among all the muscles measured. A short-term exercise training program used in this study is capable of improving muscle strength and agility performance of adolescents with DS. PMID:22820064

  15. Research on Modeling of the Agile Satellite Using a Single Gimbal Magnetically Suspended CMG and the Disturbance Feedforward Compensation for Rotors

    PubMed Central

    Cui, Peiling; Yan, Ning

    2012-01-01

    The magnetically suspended Control Moment Gyroscope (CMG) has the advantages of long-life, micro-vibration and being non-lubricating, and is the ideal actuator for agile maneuver satellite attitude control. However, the stability of the rotor in magnetic bearing and the precision of the output torque of a magnetically suspended CMG are affected by the rapid maneuvers of satellites. In this paper, a dynamic model of the agile satellite including a magnetically suspended single gimbal control moment gyroscope is built and the equivalent disturbance torque effected on the rotor is obtained. The feedforward compensation control method is used to depress the disturbance on the rotor. Simulation results are given to show that the rotor displacement is obviously reduced. PMID:23235442

  16. Research on modeling of the agile satellite using a single gimbal magnetically suspended CMG and the disturbance feedforward compensation for rotors.

    PubMed

    Cui, Peiling; Yan, Ning

    2012-01-01

    The magnetically suspended Control Moment Gyroscope (CMG) has the advantages of long-life, micro-vibration and being non-lubricating, and is the ideal actuator for agile maneuver satellite attitude control. However, the stability of the rotor in magnetic bearing and the precision of the output torque of a magnetically suspended CMG are affected by the rapid maneuvers of satellites. In this paper, a dynamic model of the agile satellite including a magnetically suspended single gimbal control moment gyroscope is built and the equivalent disturbance torque effected on the rotor is obtained. The feedforward compensation control method is used to depress the disturbance on the rotor. Simulation results are given to show that the rotor displacement is obviously reduced. PMID:23235442

  17. Modeling the Agility MLC in the Monaco treatment planning system.

    PubMed

    Snyder, Michael; Halford, Robert; Knill, Cory; Adams, Jeffrey N; Bossenberger, Todd; Nalichowski, Adrian; Hammoud, Ahmad; Burmeister, Jay

    2016-01-01

    We investigate the relationship between the various parameters in the Monaco MLC model and dose calculation accuracy for an Elekta Agility MLC. The vendor-provided MLC modeling procedure - completed first with external vendor participation and then exclusively in-house - was used in combination with our own procedures to investigate several sets of MLC modeling parameters to determine their effect on dose distributions and point-dose measurements. Simple plans provided in the vendor procedure were used to elucidate specific mechanical characteristics of the MLC, while ten complex treatment plans - five IMRT and five VMAT - created using TG-119-based structure sets were used to test clinical dosimetric effects of particular parameter choices. EDR2 film was used for the vendor fields to give high spatial resolution, while a combination of MapCHECK and ion chambers were used for the in-house TG-119-based proced-ures. The vendor-determined parameter set provided a reasonable starting point for the MLC model and largely delivered acceptable gamma pass rates for clinical plans - including a passing external evaluation using the IROC H&N phantom. However, the vendor model did not provide point-dose accuracy consistent with that seen in other treatment systems at our center. Through further internal testing it was found that there existed many sets of MLC parameters, often at opposite ends of their allowable ranges, that provided similar dosimetric characteristics and good agreement with planar and point-dose measurements. In particular, the leaf offset and tip leakage parameters compensated for one another if adjusted in opposite directions, which provided a level curve of acceptable parameter sets across all plans. Interestingly, gamma pass rates of the plans were less dependent upon parameter choices than point-dose measurements, suggesting that MLC modeling using only gamma evaluation may be generally an insufficient approach. It was also found that exploring all

  18. The Automated Assembly Team contributions to the APRIMED Agile Manufacturing Project

    SciTech Connect

    Jones, R.E.; Ames, A.L.; Calton, T.L.

    1995-06-01

    The Automated Assembly Team of the APRIMED Project (abbreviated as A{prime}) consists of two parts: the Archimedes Project, which is an ongoing project developing automated assembly technology, and the A{prime} Robot Team. Archimedes is a second generation assembly planning system that both provides a general high-level assembly sequencing capability and, for a smaller class of products, facilitates automatic programming of a robotic workcell to assemble them. The A{prime} robot team designed, developed, and implemented a flexible robot workcell which served as the automated factory of the A{prime} project. In this document we briefly describe the role of automated assembly planning in agile manufacturing, and specifically describe the contributions of the Archimedes project and the A{prime} robot team to the A{prime} project. We introduce the concepts of the Archimedes automated assembly planning project, and discuss the enhancements to Archimedes which were developed in response to the needs of the A{prime} project. We also present the work of the A{prime} robot team in designing and developing the A{prime} robot workcell, including all tooling and programming to support assembly of the A{prime} discriminator devices. Finally, we discuss the process changes which these technologies have enabled in the A{prime} project.

  19. A process for the agile product realization of electro-mechanical devices

    SciTech Connect

    Forsythe, C.; Diegert, K.V.; Ashby, M.R.; Parratt, S.W.; Benavides, G.L.; Jones, R.E.; Longcope, D.B.

    1995-08-01

    This paper describes a product realization process developed at Sandia National Laboratories by the A-PRIMED project that integrates many of the key components of ``agile manufacturing`` into a complete, step-by-step, design-to-production process. For three separate product realization efforts, each geared to a different set of requirements, A-PRIMED demonstrated product realization of a custom device in less than a month. A-PRIMED used a discriminator (a precision electro-mechanical device) as the demonstration device, but the process is readily adaptable to other electro-mechanical products. The process begins with a qualified design parameter space. From that point, the product realization process encompasses all facets of requirements development, analysis and testing, design, manufacturing, robotic assembly and quality assurance, as well as product data management and concurrent engineering. In developing the product realization process, A-PRIMED employed an iterative approach whereby after each of three builds, the process was reviewed and refinements made on the basis of lessons learned. This paper describes the integration of project functions and product realization technologies, with references to reports detailing specific facets of the overall process. The process described herein represents the outcome of an empirically-based process development effort that on repeated iterations, was proven successful.

  20. A process for the agile product realization of electromechanical devices (A-primed)

    SciTech Connect

    Forsythe, C.; Ashby, M.R.; Benavides, G.L.; Diegert, K.V.; Jones, R.E.; Longcope, D.B.; Parratt, S.W.

    1996-02-01

    This paper describes a product realization process developed at Sandia National Laboratories by the A-PRIMED project that integrates many of the key components of ``agile manufacturing`` (Nagel & Dove, 1992) into a complete, step-by-step, design-to-production process. For two separate product realization efforts, each geared to a different set of requirements, A-PRIMED demonstrated product realization of a custom device in less than a month. A-PRIMED used a discriminator (a precision electro mechanical device) as the demonstration device, but the process is readily adaptable to other electro mechanical products. The process begins with a qualified design parameter space (Diegert et al, 1995). From that point, the product realization process encompasses all facets of requirements development, analysis and testing, design, manufacturing, robot assembly and quality assurance, as well as product data management and concurrent engineering. In developing the product realization process, A-PRIMED employed an iterative approach whereby after each build, the process was reviewed and refinements were made on the basis of lessons learned. This paper describes the integration of project functions and product realization technologies to develop a product realization process that on repeated iterations, was proven successful.

  1. Commissioning the CERN IT Agile Infrastructure with experiment workloads

    NASA Astrophysics Data System (ADS)

    Medrano Llamas, Ramón; Harald Barreiro Megino, Fernando; Kucharczyk, Katarzyna; Kamil Denis, Marek; Cinquilli, Mattia

    2014-06-01

    In order to ease the management of their infrastructure, most of the WLCG sites are adopting cloud based strategies. In the case of CERN, the Tier 0 of the WLCG, is completely restructuring the resource and configuration management of their computing center under the codename Agile Infrastructure. Its goal is to manage 15,000 Virtual Machines by means of an OpenStack middleware in order to unify all the resources in CERN's two datacenters: the one placed in Meyrin and the new on in Wigner, Hungary. During the commissioning of this infrastructure, CERN IT is offering an attractive amount of computing resources to the experiments (800 cores for ATLAS and CMS) through a private cloud interface. ATLAS and CMS have joined forces to exploit them by running stress tests and simulation workloads since November 2012. This work will describe the experience of the first deployments of the current experiment workloads on the CERN private cloud testbed. The paper is organized as follows: the first section will explain the integration of the experiment workload management systems (WMS) with the cloud resources. The second section will revisit the performance and stress testing performed with HammerCloud in order to evaluate and compare the suitability for the experiment workloads. The third section will go deeper into the dynamic provisioning techniques, such as the use of the cloud APIs directly by the WMS. The paper finishes with a review of the conclusions and the challenges ahead.

  2. MiniMAX: miniature, mobile, agile, x-ray system

    NASA Astrophysics Data System (ADS)

    Watson, Scott A.; Cunningham, Gwynneth; Gonzales, Samuel

    2012-06-01

    We present a unique, lightweight, compact, low-cost, x-ray imager: MiniMAX (Miniature, Mobile, Agile, X-ray). This system, which exploits the best aspects of Computed Radiography (CR) and Digital Radiography (DR) technology, weighs less than 6lbs, fits into a 6" diameter x 16" long carbon-fiber tube, and is constructed almost entirely from offthe- shelf components. MiniMAX is suitable for use in weld inspection, archaeology, homeland security, and veterinary medicine. While quantum limited for MeV radiography, the quantum-efficiency is too low for routine medical use. Formats include: 4"x6", 8"x12", or 16"x24" and can be readily displayed on the camera back, using a pocket projector, or on a tablet computer. In contrast to a conventional, flying-spot scanner, MiniMAX records a photostimulated image from the entire phosphor at once using a bright, red LED flash filtered through an extremely efficient (OD>9) dichroic filter.

  3. Resonance versus aerodynamics for energy savings in agile natural flyers

    NASA Astrophysics Data System (ADS)

    Kok, Jia M.; Chahl, Javaan

    2014-03-01

    Insects are the most diverse natural flyers in nature, being able to hover and perform agile manoeuvres. Dragon- flies in particular are aggressive flyers, attaining accelerations of up to 4g. Flight in all insects requires demanding aerodynamic and inertial loads be overcome. It has been proposed that resonance is a primary mechanism for reducing energy costs associated with flapping flight, by storing energy in an elastic thorax and releasing it on the following half-stroke. Certainly in insect flight motors dominated by inertial loads, such a mechanism would be extremely beneficial. However in highly manoeuvrable, aerodynamically dominated flyers, such as the dragonfly, the use of elastic storage members requires further investigation. We show that employing resonant mechanisms in a real world configuration produces minimal energy savings that are further reduced by 50 to 133% across the operational flapping frequency band of the dragonfly. Using a simple harmonic oscillator analysis to represent the dynamics of a dragonfly, we further demonstrate a reduction in manoeuvring limits of ˜1.5 times for a system employing elastic mechanisms. This is in contrast to the potential power reductions of √2/2 from regulating aerodynamics via active wing articulation. Aerodynamic means of energy storage provides flexibility between an energy efficient hover state and a manoeuvrable state capable of large accelerations. We conclude that active wing articulation is preferable to resonance for aerodynamically dominated natural flyers.

  4. The AGILE-MCAL instrument as TGF monitor

    NASA Astrophysics Data System (ADS)

    Longo, F.; Marisaldi, M.; Fuschino, F.; Labanti, C.; Galli, M.

    2008-12-01

    The Mini-Calorimeter detector on-board the AGILE satellite was designed for astrophysical observations in the gamma-ray field, including cosmological Gamma-Ray-Burst (GRB). Thanks to its flexible on-board trigger logic for transient event, since the beginning of its operation, in April 2007, MCAL was also able to detect very fast transient phenomena in the energy range from 0.3 up to several MeV. These exhibit the characteristic of Terrestrial Gamma-ray Flashes (TGF). The candidate MCAL TGF events have a duration that can last from some hundred of μsec. to some millisec and reaches up to MeV in energy. For each triggered TGF its photon-by-photon history is recorded, with every photon described with energy, position on the detector plane and time (2 μsec. resolution) data. The on-ground data analysis strategy, based on more sophisticated algorithm than on-board logic, allows to discriminate between cosmological GRB and TGF and then to supply the spectral fluxes and the incoming area on the heart, within a 2000 km circle, of the observed TGF. MCAL can be then be used to increase the statistic of observed TGFs in the gamma ray domain and eventually to correlate them with observation in other energy ranges. The MCAL TGF observation strategy, as well as a short catalogue of detects events will be described and discussed.

  5. Method Development and Monitoring of Cyanotoxins in Water

    EPA Science Inventory

    This presentation describes method development of two ambient water LC/MS/MS methods for microcystins, cylindrospermopsin and anatoxin-a. Ruggedness of the methods will be demonstrated by evaluation of quality control samples derived from various water bodies across the country.

  6. Development of quality assurance methods for epoxy graphite prepreg

    NASA Technical Reports Server (NTRS)

    Chen, J. S.; Hunter, A. B.

    1982-01-01

    Quality assurance methods for graphite epoxy/prepregs were developed. Liquid chromatography, differential scanning calorimetry, and gel permeation chromatography were investigated. These methods were applied to a second prepreg system. The resin matrix formulation was correlated with mechanical properties. Dynamic mechanical analysis and fracture toughness methods were investigated. The chromatography and calorimetry techniques were all successfully developed as quality assurance methods for graphite epoxy prepregs. The liquid chromatography method was the most sensitive to changes in resin formulation. The were also successfully applied to the second prepreg system.

  7. Validity and Reliability of New Agility Test among Elite and Subelite under 14-Soccer Players

    PubMed Central

    Hachana, Younés; Chaabène, Helmi; Ben Rajeb, Ghada; Khlifa, Riadh; Aouadi, Ridha; Chamari, Karim; Gabbett, Tim J.

    2014-01-01

    Background Agility is a determinant component in soccer performance. This study aimed to evaluate the reliability and sensitivity of a “Modified Illinois change of direction test” (MICODT) in ninety-five U-14 soccer players. Methods A total of 95 U-14 soccer players (mean ± SD: age: 13.61±1.04 years; body mass: 30.52±4.54 kg; height: 1.57±0.1 m) from a professional and semi-professional soccer academy, participated to this study. Sixty of them took part in reliability analysis and thirty-two in sensitivity analysis. Results The intraclass correlation coefficient (ICC) that aims to assess relative reliability of the MICODT was of 0.99, and its standard error of measurement (SEM) for absolute reliability was <5% (1.24%). The MICODT’s capacity to detect change is “good”, it’s SEM (0.10 s) was ≤ SWC (0.33 s). The MICODT is significantly correlated to the Illinois change of direction speed test (ICODT) (r = 0.77; p<0.0001). The ICODT’s MDC95 (0.64 s) was twice about the MICODT’s MDC95 (0.28 s), indicating that MICODT presents better ability to detect true changes than ICODT. The MICODT provided good sensitivity since elite U-14 soccer players were better than non-elite one on MICODT (p = 0.005; dz = 1.01 [large]). This was supported by an area under the ROC curve of 0.77 (CI 95%, 0.59 to 0.89, p<0.0008). The difference observed in these two groups in ICODT was not statistically significant (p = 0.14; dz = 0.51 [small]), showing poor discriminant ability. Conclusion MICODT can be considered as more suitable protocol for assessing agility performance level than ICODT in U-14 soccer players. PMID:24752193

  8. X-36 Tailless Fighter Agility Research Aircraft on lakebed during high-speed taxi tests

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The NASA/McDonnell Douglas Corporation (MDC) X-36 Tailless Fighter Agility Research Aircraft undergoes high-speed taxi tests on Rogers Dry Lake at NASA Dryden Flight Research Center, Edwards, California, on October 17, 1996. The aircraft was tested at speeds up to 85 knots. Normal takeoff speed would be 110 knots. More taxi and radio frequency tests were slated before it's first flight would be made. This took place on May 17, 1997. The NASA/Boeing X-36 Tailless Fighter Agility Research Aircraft program successfully demonstrated the tailless fighter design using advanced technologies to improve the maneuverability and survivability of possible future fighter aircraft. The program met or exceeded all project goals. For 31 flights during 1997 at the Dryden Flight Research Center, Edwards, California, the project team examined the aircraft's agility at low speed / high angles of attack and at high speed / low angles of attack. The aircraft's speed envelope reached up to 206 knots (234 mph). This aircraft was very stable and maneuverable. It handled very well. The X-36 vehicle was designed to fly without the traditional tail surfaces common on most aircraft. Instead, a canard forward of the wing was used as well as split ailerons and an advanced thrust-vectoring nozzle for directional control. The X-36 was unstable in both pitch and yaw axes, so an advanced, single-channel digital fly-by-wire control system (developed with some commercially available components) was put in place to stabilize the aircraft. Using a video camera mounted in the nose of the aircraft and an onboard microphone, the X-36 was remotely controlled by a pilot in a ground station virtual cockpit. A standard fighter-type head-up display (HUD) and a moving-map representation of the vehicle's position within the range in which it flew provided excellent situational awareness for the pilot. This pilot-in-the-loop approach eliminated the need for expensive and complex autonomous flight control systems

  9. X-36 Tailless Fighter Agility Research Aircraft on lakebed during high-speed taxi tests

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The NASA/McDonnell Douglas Corporation (MDC) X-36 Tailless Fighter Agility Research Aircraft undergoes high-speed taxi tests on Rogers Dry Lake at NASA Dryden Flight Research Center, Edwards, California, on October 17, 1996. The aircraft was tested at speeds up to 85 knots. Normal takeoff speed would be 110 knots. The NASA/Boeing X-36 Tailless Fighter Agility Research Aircraft program successfully demonstrated the tailless fighter design using advanced technologies to improve the maneuverability and survivability of possible future fighter aircraft. The program met or exceeded all project goals. For 31 flights during 1997 at the Dryden Flight Research Center, Edwards, California, the project team examined the aircraft's agility at low speed / high angles of attack and at high speed / low angles of attack. The aircraft's speed envelope reached up to 206 knots (234 mph). This aircraft was very stable and maneuverable. It handled very well. The X-36 vehicle was designed to fly without the traditional tail surfaces common on most aircraft. Instead, a canard forward of the wing was used as well as split ailerons and an advanced thrust-vectoring nozzle for directional control. The X-36 was unstable in both pitch and yaw axes, so an advanced, single-channel digital fly-by-wire control system (developed with some commercially available components) was put in place to stabilize the aircraft. Using a video camera mounted in the nose of the aircraft and an onboard microphone, the X-36 was remotely controlled by a pilot in a ground station virtual cockpit. A standard fighter-type head-up display (HUD) and a moving-map representation of the vehicle's position within the range in which it flew provided excellent situational awareness for the pilot. This pilot-in-the-loop approach eliminated the need for expensive and complex autonomous flight control systems and the risks associated with their inability to deal with unknown or unforeseen phenomena in flight. Fully fueled the X

  10. A random spatial sampling method in a rural developing nation

    PubMed Central

    2014-01-01

    Background Nonrandom sampling of populations in developing nations has limitations and can inaccurately estimate health phenomena, especially among hard-to-reach populations such as rural residents. However, random sampling of rural populations in developing nations can be challenged by incomplete enumeration of the base population. Methods We describe a stratified random sampling method using geographical information system (GIS) software and global positioning system (GPS) technology for application in a health survey in a rural region of Guatemala, as well as a qualitative study of the enumeration process. Results This method offers an alternative sampling technique that could reduce opportunities for bias in household selection compared to cluster methods. However, its use is subject to issues surrounding survey preparation, technological limitations and in-the-field household selection. Application of this method in remote areas will raise challenges surrounding the boundary delineation process, use and translation of satellite imagery between GIS and GPS, and household selection at each survey point in varying field conditions. This method favors household selection in denser urban areas and in new residential developments. Conclusions Random spatial sampling methodology can be used to survey a random sample of population in a remote region of a developing nation. Although this method should be further validated and compared with more established methods to determine its utility in social survey applications, it shows promise for use in developing nations with resource-challenged environments where detailed geographic and human census data are less available. PMID:24716473

  11. Array Databases: Agile Analytics (not just) for the Earth Sciences

    NASA Astrophysics Data System (ADS)

    Baumann, P.; Misev, D.

    2015-12-01

    Gridded data, such as images, image timeseries, and climate datacubes, today are managed separately from the metadata, and with different, restricted retrieval capabilities. While databases are good at metadata modelled in tables, XML hierarchies, or RDF graphs, they traditionally do not support multi-dimensional arrays.This gap is being closed by Array Databases, pioneered by the scalable rasdaman ("raster data manager") array engine. Its declarative query language, rasql, extends SQL with array operators which are optimized and parallelized on server side. Installations can easily be mashed up securely, thereby enabling large-scale location-transparent query processing in federations. Domain experts value the integration with their commonly used tools leading to a quick learning curve.Earth, Space, and Life sciences, but also Social sciences as well as business have massive amounts of data and complex analysis challenges that are answered by rasdaman. As of today, rasdaman is mature and in operational use on hundreds of Terabytes of timeseries datacubes, with transparent query distribution across more than 1,000 nodes. Additionally, its concepts have shaped international Big Data standards in the field, including the forthcoming array extension to ISO SQL, many of which are supported by both open-source and commercial systems meantime. In the geo field, rasdaman is reference implementation for the Open Geospatial Consortium (OGC) Big Data standard, WCS, now also under adoption by ISO. Further, rasdaman is in the final stage of OSGeo incubation.In this contribution we present array queries a la rasdaman, describe the architecture and novel optimization and parallelization techniques introduced in 2015, and put this in context of the intercontinental EarthServer initiative which utilizes rasdaman for enabling agile analytics on Petascale datacubes.

  12. EPA (ENVIRONMENTAL PROTECTION AGENCY) DEVELOPING METHODS TO ASSESS ENVIRONMENTAL RELEASE

    EPA Science Inventory

    The EPA has invested considerable research effort--intended to meet regulatory needs--toward developing methods for assessing the environmental effects of genetically engineered microorganisms (GEMs). Preliminary investigations centered on the fate, survival, accidental release, ...

  13. XENOBIOTIC METHODS DEVELOPMENT FOR HUMAN EXPOSURE ASSESSMENT RESEARCH

    EPA Science Inventory

    Biomarkers from blood, breath, urine, and other physiological matrices can provide useful information regarding exposures to environmental pollutants. Once developed and applied appropriately, specific and sensitive methods can often provide definitive data identifying the vario...

  14. 3-minute diagnosis: Researchers develop new method to recognize pathogens

    ScienceCinema

    Beer, Reg

    2014-05-30

    Imagine knowing precisely why you feel sick ... before the doctor's exam is over. Lawrence Livermore researcher Reg Beer and his engineering colleagues have developed a new method to recognize disease-causing pathogens quicker than ever before.

  15. 3-minute diagnosis: Researchers develop new method to recognize pathogens

    SciTech Connect

    Beer, Reg

    2014-01-06

    Imagine knowing precisely why you feel sick ... before the doctor's exam is over. Lawrence Livermore researcher Reg Beer and his engineering colleagues have developed a new method to recognize disease-causing pathogens quicker than ever before.

  16. Development of methods for orderly growth of nanowires

    NASA Astrophysics Data System (ADS)

    Reznik, R. R.; Kotlyar, K. P.; Khrebtov, A. I.; Samsonenko, Yu B.; Soshnikov, I. P.; Dyakonov, V.; Zadiranov, U. M.; Tankelevskaya, E. M.; Kudryashov, D. A.; Shevchuk, D. S.; Cirlin, G. E.

    2015-12-01

    Method of manufacturing substrates for self-catalyst/free-catalyst ordered growth of the nanowires has been developed. Experiments show the possibility of autocatalytic growth of ordered GaAs NWs on the substrates produced during the research.

  17. Development of aerodynamic prediction methods for irregular planform wings

    NASA Technical Reports Server (NTRS)

    Benepe, D. B., Sr.

    1983-01-01

    A set of empirical methods was developed to predict low-speed lift, drag and pitching-moment variations with angle of attack for a class of low aspect ratio irregular planform wings suitable for application to advanced aerospace vehicles. The data base, an extensive series of wind-tunnel tests accomplished by the Langley Research Center of the National Aeronautics and Space Administration, is summarized. The approaches used to analyze the wind tunnel data, the evaluation of previously existing methods, data correlation efforts, and the development of the selected methods are presented and discussed. A summary of the methods is also presented to document the equations, computational charts and design guides which have been programmed for digital computer solution. Comparisons of predictions and test data are presented which show that the new methods provide a significant improvement in capability for evaluating the landing characteristics of advanced aerospace vehicles during the preliminary design phase of the configuration development cycle.

  18. Prospects of High Energy Studies of Pulsars with the AGILE Gamma-ray Telescope

    NASA Astrophysics Data System (ADS)

    Pellizzoni, A.; Mereghetti, S.; Tavani, M.; Chen, A.; Giuliani, A.; Vercellone, S.

    AGILE is a small gamma-ray astronomy mission of the Italian Space Agency, with good spatial resolution, excellent timing capability and an unprecedently large field of view (~1/4 of the sky). It will be the only mission dedicated to high energy astrophysics in the range 30 MeV-50 GeV during the period 2003-2006, before the launch of GLAST. Besides studying the small sample of known gamma-ray pulsars, AGILE will offer the first possibility to detect several young and energetic radio pulsars that have been discovered after the end of the CGRO mission. AGILE will contribute to the study of gamma-ray pulsars in several ways: (1) improving photon statistics for gamma-ray pulsations searches; (2) detecting possible secular variations of the gamma-ray emission from neutron star magnetospheres; (3) studying unpulsed gamma-ray emission from plerions in supernova remnants and searching for time variability of pulsar wind/nebula interactions; (4) helping to understand the population of unidentified EGRET sources that might consist in part of radio-quiet pulsars. We will describe the AGILE satellite and provide an estimate of the expected number of the detectable gamma-ray pulsars. The AGILE capabilities for the detection of gamma-ray pulsars with small counting statistics will be presented based on the analysis of data from simulations and from the EGRET archive.

  19. The Agile Gamma-Ray Mission and Gamma-Ray Burst Studies

    NASA Astrophysics Data System (ADS)

    Longo, Francesco; Tavani, Marco; Argan, Andrea; Caraveo, Patrizia; Chen, Andrew; Fiorini, Mauro; Giuliani, Andrea; Mereghetti, Sandro; Perotti, Francesco; Vercellone, Stefano; Barbiellini, Guido; Fedel, Giulio; Pontoni, Cristian; Prest, Michela; Vallazza, Erik; Costa, Enrico; Feroci, Marco; Lapshov, Igor; Rapisarda, Massimo; Rubini, Alda; Soffitta, Paolo; Cocco, Veronica; Morselli, Aldo; Picozza, Piergiorgio; Pittori, Carlotta; Auricchio, Natalia; Di Cocco, Guido; Galli, Marcello; Labanti, Claudio; Morelli, Ennio; Rossi, Elio; Trifoglio, Massimo; Lipari, Paolo; Zanello, Dino

    2002-12-01

    The AGILE satellite (the first of ASI Small Scientific Missions) is planned to be operational in 2003 and will be the only space mission entirely dedicated to gamma-ray astrophysics in the energy range 30 MeV - 50 GeV. AGILE is based on innovative solid state detector technology and will have two imaging detectors: a Silicon tracker (30 MeV-50 GeV), and a coded mask system with Si detectors (Super-AGILE, 10-40 keV). In addition, a CsI Mini-Calorimeter will be able to detect gamma-rays in the range 250 keV - 200 MeV. The instrument large field of view (~1/4 of the whole sky), excellent spatial resolution (a few arcminutes for Super-AGILE, 10-20 arcminutes for the Si-tracker), and unprecedented timing resolution and short deadtimes (~5-100 microseconds) improving EGRET capabilities by three orders of magnitude make of AGILE an ideal instrument to detect gamma-ray bursts

  20. A yaw-moment control method based on a vehicle's lateral jerk information

    NASA Astrophysics Data System (ADS)

    Yamakado, Makoto; Nagatsuka, Keiichiro; Takahashi, Junya

    2014-10-01

    Previously, a new control concept called 'G-vectoring control (GVC)' to improve vehicle agility and stability was developed. GVC is an automatic longitudinal acceleration control method that responds to vehicle lateral jerk caused by the driver's steering manoeuvres. In this paper, a new yaw-moment control method, which generates a stabilising moment during the GVC command and has positive acceleration value and the driver's accelerator pedal input is zero, was proposed. A new hybrid control, which comprises GVC, electric stability control and this new control, was constructed, and it was installed in a test vehicle and tested on a snowy surface. The very high potential for improvement in both agility and stability was confirmed.

  1. AN APPROACH TO METHODS DEVELOPMENT FOR HUMAN EXPOSURE ASSESSMENT STUDIES

    EPA Science Inventory

    Human exposure assessment studies require methods that are rapid, cost-effective and have a high sample through-put. The development of analytical methods for exposure studies should be based on specific information for individual studies. Human exposure studies suggest that di...

  2. What Can Mixed Methods Designs Offer Professional Development Program Evaluators?

    ERIC Educational Resources Information Center

    Giordano, Victoria; Nevin, Ann

    2007-01-01

    In this paper, the authors describe the benefits and pitfalls of mixed methods designs. They argue that mixed methods designs may be preferred when evaluating professional development programs for p-K-12 education given the new call for accountability in making data-driven decisions. They summarize and critique the studies in terms of limitations…

  3. DEVELOPMENT OF SAMPLING METHODS FOR SOURCE PM10 EMISSIONS

    EPA Science Inventory

    The report describes an investigation of the needs and available techniques for in-stack PM-10 sampling. Discussion includes the conceptualization, development, documentation, and testing of two candidate methods. The first method, Constant Sampling Rate (CSR), is a procedural ap...

  4. Epistemological Development and Judgments and Reasoning about Teaching Methods

    ERIC Educational Resources Information Center

    Spence, Sarah; Helwig, Charles C.

    2013-01-01

    Children's, adolescents', and adults' (N = 96 7-8, 10-11, and 13-14-year-olds and university students) epistemological development and its relation to judgments and reasoning about teaching methods was examined. The domain (scientific or moral), nature of the topic (controversial or noncontroversial), and teaching method (direct…

  5. Recent developments in synthetic methods for benzo[b]heteroles.

    PubMed

    Wu, Bin; Yoshikai, Naohiko

    2016-06-28

    Benzo[b]heteroles containing heteroatoms other than nitrogen and oxygen have received considerable attention for their potential applications in materials science. This poses an increasing demand for efficient, selective, and broad-scope methods for their synthesis. This review article summarizes the recent developments in synthetic methods and approaches to access representative members of the benzoheterole family. PMID:26892101

  6. A Model-Driven Development Method for Management Information Systems

    NASA Astrophysics Data System (ADS)

    Mizuno, Tomoki; Matsumoto, Keinosuke; Mori, Naoki

    Traditionally, a Management Information System (MIS) has been developed without using formal methods. By the informal methods, the MIS is developed on its lifecycle without having any models. It causes many problems such as lack of the reliability of system design specifications. In order to overcome these problems, a model theory approach was proposed. The approach is based on an idea that a system can be modeled by automata and set theory. However, it is very difficult to generate automata of the system to be developed right from the start. On the other hand, there is a model-driven development method that can flexibly correspond to changes of business logics or implementing technologies. In the model-driven development, a system is modeled using a modeling language such as UML. This paper proposes a new development method for management information systems applying the model-driven development method to a component of the model theory approach. The experiment has shown that a reduced amount of efforts is more than 30% of all the efforts.

  7. Clean, agile alternative binders, additives and plasticizers for propellant and explosive formulations

    SciTech Connect

    Hoffman, D.M.; Hawkins, T.W.; Lindsay, G.A.

    1994-12-01

    As part of the Strategic Environmental Research and Development Program (SERDP) a clean, agile manufacturing of explosives, propellants and pyrotechniques (CANPEP) effort set about to identify new approaches to materials and processes for producing propellants, explosives and pyrotechniques (PEP). The RDX based explosive PBXN-109 and gun propellant M-43 were identified as candidates for which waste minimization and recycling modifications might be implemented in a short time frame. The binders, additives and plasticizers subgroup identified cast non-curable thermoplastic elastomer (TPE) formulations as possible replacement candidates for these formulations. Paste extrudable explosives were also suggested as viable alternatives to PBXN-109. Commercial inert and energetic TPEs are reviewed. Biodegradable and hydrolyzable binders are discussed. The applicability of various types of explosive formulations are reviewed and some issues associated with implementation of recyclable formulations are identified. It is clear that some processing and weaponization modifications will need to be made if any of these approaches are to be implemented. The major advantages of formulations suggested here over PBXN-109 and M-43 is their reuse/recyclability. Formulations using TPE or Paste could by recovered from a generic bomb or propellant and reused if they met specification or easily reprocessed and sold to the mining industry.

  8. Plug-and-play open architecture integration of mechatronic systems for agile manufacturing

    NASA Astrophysics Data System (ADS)

    Cheng, Harry H.

    1997-01-01

    A plug-and-play open architecture language environment for integration of mechatronic systems for agile manufacturing will be presented in this paper. This new language environment is designed to be computer platform independent, mechatronic device independent, and mechatronic system independent. The language environment is a salient extension and enhancement of Unix/Windows/C computing environment, popularly used by engineers and scientists all over the world. The language environment for real-time operation of mechatronic systems is a superset of interpretive C programming language implemented as a shell. We have designed and implemented this interpretive language environment with security provisions for cross-platform network computing. The mechatronic systems under this new integration paradigm, therefore, can be remotely operated thousands of miles away from the physical site across the network. An experimental rapid prototype system has been developed to verify our principles and algorithms on open architecture integration of mechatronic system. Hardware from different vendors can be easily plugged into the prototype system and the user can readily play it without changing application programs written in the superset of C. The new integration language environment is available for downloading on the WWW at the URL address.

  9. Backscatter measurements of aerosolized CB simulants with a frequency agile CO2 lidar

    NASA Astrophysics Data System (ADS)

    Vanderbeek, Richard; Gurton, Kristan

    2004-02-01

    A novel windowless chamber was developed to allow aerosol backscatter measurements with a frequency-agile CO2 lidar. The chamber utilizes curtains of air to contain the cloud, thus preventing the inevitable backscatter off of conventional windows from corrupting the desired measurements. This feature is critical because the CO2 lidar has a long (1 μs) pulse and the backscatter off the window cannot be temporally separated from the backscatter off the aerosol in the chamber. The chamber was designed for testing with a variety of CB simulants and interferents in both vapor and aerosol form and has been successfully shown to contain a cloud of known size, concentration, and particle size distribution for 10-15 minutes. This paper shows the results using Arizona road dust that was screened by the manufacturer into 0-3 μm and 5-10 μm particle size distributions. The measurements clearly show the effect of size distribution on the infrared backscatter coefficients as well as the dynamic nature of the size distribution for a population of aerosols. The test methodology and experimental results are presented.

  10. A Study on Reclaimed Photoresist Developer Using an Electrodialysis Method

    NASA Astrophysics Data System (ADS)

    Sugawara, Hiroshi; Tajima, Yoshinori; Ohmi, Tadahiro

    2002-04-01

    Photoresist developer reclamation technology and systems have been investigated and characteristics of the reclaimed developer were evaluated. High-purity tetramethylammonium hydroxide (TMAH) aqueous solution adjusted to an appropriate concentration is generally used as the photoresist developer in the lithography step for large scale integration (LSI) and liquid crystal display (LCD) manufacturing processes. TMAH was recovered by an electrodialysis (ED) method from developer waste (spent developer), and purified by ion exchange (IE) technologies. The reclaimed developer was analyzed and found to feature the same purity as fresh commercial developer and no differences in their characteristics as developer material could be determined. Our experimental reclamation system recovered more than 80% of stable TMAH from waste and, moreover, achieved large reductions in operating costs, which amounted to total cost reductions of 55-75% for LSI and 65-85% for LCD compared with the conventional systems without reclamation studied by us. In addition, environmental load was reduced.

  11. A review of the multiwavelength studies on the blazars detected by AGILE

    NASA Astrophysics Data System (ADS)

    Donnarumma, Immacolata; AGILE Team

    2012-03-01

    We report on the main results on gamma-ray blazars as obtained by AGILE during 4 years in orbit. AGILE detected several flaring blazars, mostly FSRQs, which were studied from radio to TeV energy bands thanks to the rapid dissemination of our alerts. In particular, we carried out several multifrequency campaigns resulted from the synergy with other observatories such as GASP-WEBT (GLAST-AGILE Support Programme of the Whole Earth Blazar Telescope network), REM, Spitzer, Swift, RXTE, XMM-Newton, Suzaku, INTEGRAL, MAGIC, VERITAS. Temporal and SED variabilities were studied in details thanks to the large set of simultaneous data. The most relevant properties of our sample of blazars will be presented with a particular emphasis on the spectral thermal components, time lags, spectral trends (in X-rays and gamma-rays), jet geometry and acceleration mechanism at the inner portion of the jet itself.

  12. Development and applications of Krotov method of global control improvement

    NASA Astrophysics Data System (ADS)

    Rasina, Irina V.; Trushkova, Ekaterina A.; Baturina, Olga V.; Bulatov, Alexander V.; Guseva, Irina S.

    2016-06-01

    This is a survey of works on main properties, application and development of the Krotov method of global control improvement very popular among researchers of modern problems in quantum physics and quantum chemistry, applying actively optimal control methods. The survey includes a brief description of the method in comparison with well known gradient method demonstrating such its serious advantage as absence of tuning parameters; investigations aimed to make its special version for the quantum system well defined and more effective; and generalization for wide classes of control systems, including the systems of heterogeneous structure.

  13. Acute Effects of Static and Dynamic Stretching on Balance, Agility, Reaction Time and Movement Time

    PubMed Central

    Chatzopoulos, Dimitris; Galazoulas, Christos; Patikas, Dimitrios; Kotzamanidis, Christos

    2014-01-01

    The purpose of this study was to compare the acute effects of three different stretching protocols on balance, agility, reaction time and movement time of the upper limbs. Participants were thirty one female high school athletes (age = 17.3 ± 0.5 yr.). All participants performed one of the following protocols on different days: (a) 3 min jogging followed by 7 min static stretching (SS), (b) 3 min jogging followed by 7 min dynamic stretching (DS), and (c) 3 min jogging followed by 7 min of rest (NS). After the protocols participants performed the following tests: dynamic balance, 505 agility test, reaction time (time between a sound stimulus and release of a button) and movement time (movement of the upper extremity over a 0.5 m distance). The order of stretching protocols and performance tests were counterbalanced to avoid carryover effects. Repeated measures analysis of variance revealed significant main effects for all variables except reaction time. The DS protocol compared to SS performed significantly better in balance, agility and movement time. Additionally, the DS protocol compared to NS performed significantly better in agility. According to the results of the study, a DS protocol is more appropriate than SS for activities that require balance, rapid change of running direction (agility) and movement time of the upper extremities. Key points Static stretching has a negative effect on balance and agility performance compared to dynamic stretching. There was no effect of the stretching protocols on reaction time. Dynamic stretching was more effective than static stretching for increasing movement time of the upper extremities. PMID:24790497

  14. Beam modeling and VMAT performance with the Agility 160-leaf multileaf collimator.

    PubMed

    Bedford, James L; Thomas, Michael D R; Smyth, Gregory

    2013-01-01

    The Agility multileaf collimator (Elekta AB, Stockholm, Sweden) has 160 leaves of projected width 0.5 cm at the isocenter, with maximum leaf speed 3.5 cms-1. These characteristics promise to facilitate fast and accurate delivery of radiotherapy, particularly volumetric-modulated arc therapy (VMAT). The aim of this study is therefore to create a beam model for the Pinnacle3 treatment planning system (Philips Radiation Oncology Systems, Fitchburg, WI), and to use this beam model to explore the performance of the Agility MLC in delivery of VMAT. A 6 MV beam model was created and verified by measuring doses under irregularly shaped fields. VMAT treatment plans for five typical head-and-neck patients were created using the beam model and delivered using both binned and continuously variable dose rate (CVDR). Results were compared with those for an MLCi unit without CVDR. The beam model has similar parameters to those of an MLCi model, with interleaf leakage of only 0.2%. The verification of irregular fields shows a mean agreement between measured and planned dose of 1.3% (planned dose higher). The Agility VMAT head-and-neck plans show equivalent plan quality and delivery accuracy to those for an MLCi unit, with 95% of verification measurements within 3% and 3 mm of planned dose. Mean delivery time is 133 s with the Agility head and CVDR, 171 s without CVDR, and 282 s with an MLCi unit. Pinnacle3 has therefore been shown to model the Agility MLC accurately, and to provide accurate VMAT treatment plans which can be delivered significantly faster with Agility than with an MLCi. PMID:23470941

  15. A Literature Review on the Progression of Agile Manufacturing Paradigm and Its Scope of Application in Pump Industry.

    PubMed

    Thilak, V M M; Devadasan, S R; Sivaram, N M

    2015-01-01

    During the recent years, the manufacturing world has been witnessing the application of agile manufacturing paradigm. The literature review reported in this paper was carried out to study this progression. This literature review was carried out in two phases. In the first phase, the literature was reviewed to trace the origin of agile manufacturing paradigm and identify its enablers. Further, during this phase, the applications of agile manufacturing reported in literature arena were reviewed. It was also discernable that certain research works have been initiated to apply agile manufacturing paradigm in pump industry. During the second phase, the researches reported on applying agile manufacturing in pump industry were reviewed. At the end of this review, it was found that so far the implementation of agile manufacturing in pump industry has been examined by the researchers by considering only certain components of pumps. In fact, the holistic implementation of agile manufacturing in the pump industry is yet to be examined by the researchers. In the context of drawing this inference, this paper has been concluded by stating that high scope exists in examining the infusing of agility characteristics in designing and manufacturing of pumps. PMID:26065016

  16. A Literature Review on the Progression of Agile Manufacturing Paradigm and Its Scope of Application in Pump Industry

    PubMed Central

    Devadasan, S. R.; Sivaram, N. M.

    2015-01-01

    During the recent years, the manufacturing world has been witnessing the application of agile manufacturing paradigm. The literature review reported in this paper was carried out to study this progression. This literature review was carried out in two phases. In the first phase, the literature was reviewed to trace the origin of agile manufacturing paradigm and identify its enablers. Further, during this phase, the applications of agile manufacturing reported in literature arena were reviewed. It was also discernable that certain research works have been initiated to apply agile manufacturing paradigm in pump industry. During the second phase, the researches reported on applying agile manufacturing in pump industry were reviewed. At the end of this review, it was found that so far the implementation of agile manufacturing in pump industry has been examined by the researchers by considering only certain components of pumps. In fact, the holistic implementation of agile manufacturing in the pump industry is yet to be examined by the researchers. In the context of drawing this inference, this paper has been concluded by stating that high scope exists in examining the infusing of agility characteristics in designing and manufacturing of pumps. PMID:26065016

  17. Validation of Analytical Methods for Biomarkers Employed in Drug Development

    PubMed Central

    Chau, Cindy H.; Rixe, Olivier; McLeod, Howard; Figg, William D.

    2008-01-01

    The role of biomarkers in drug discovery and development has gained precedence over the years. As biomarkers become integrated into drug development and clinical trials, quality assurance and in particular assay validation becomes essential with the need to establish standardized guidelines for analytical methods used in biomarker measurements. New biomarkers can revolutionize both the development and use of therapeutics, but is contingent upon the establishment of a concrete validation process that addresses technology integration and method validation as well as regulatory pathways for efficient biomarker development. This perspective focuses on the general principles of the biomarker validation process with an emphasis on assay validation and the collaborative efforts undertaken by various sectors to promote the standardization of this procedure for efficient biomarker development. PMID:18829475

  18. Between Oais and Agile a Dynamic Data Management Approach

    NASA Astrophysics Data System (ADS)

    Bennett, V. L.; Conway, E. A.; Waterfall, A. M.; Pepler, S.

    2015-12-01

    In this paper we decribe an approach to the integration of existing archival activities which lies between compliance with the more rigid OAIS/TRAC standards and a more flexible "Agile" approach to the curation and preservation of Earth Observation data. We provide a high level overview of existing practice and discuss how these procedures can be extended and supported through the description of preservation state. The aim of which is to facilitate the dynamic controlled management of scientific data through its lifecycle. While processes are considered they are not statically defined but rather driven by human interactions in the form of risk management/review procedure that produce actionable plans, which are responsive to change. We then proceed by describing the feasibility testing of extended risk management and planning procedures which integrate current practices. This was done through the CEDA Archival Format Audit which inspected British Atmospheric Data Centre and NERC Earth Observation Data Centre Archival holdings. These holdings are extensive, comprising of around 2 Petabytes of data and 137 million individual files, which were analysed and characterised in terms of format, based risk. We are then able to present an overview of the format based risk burden faced by a large scale archive attempting to maintain the usability of heterogeneous environmental data sets We continue by presenting a dynamic data management information model and provide discussion of the following core model entities and their relationships: Aspirational entities, which include Data Entity definitions and their associated Preservation Objectives. Risk entities, which act as drivers for change within the data lifecycle. These include Acquisitional Risks, Technical Risks, Strategic Risks and External Risks Plan entities, which detail the actions to bring about change within an archive. These include Acquisition Plans, Preservation Plans and Monitoring plans which support

  19. AGILE detection of increased gamma-ray emission from the FSRQ PKS 1313-333

    NASA Astrophysics Data System (ADS)

    Lucarelli, F.; Verrecchia, F.; Bulgarelli, A.; Pittori, C.; Tavani, M.; Fioretti, V.; Zoli, A.; Vercellone, S.; Donnarumma, I.; Piano, G.; Striani, E.; Cardillo, M.; Gianotti, F.; Trifoglio, M.; Giuliani, A.; Mereghetti, S.; Caraveo, P.; Perotti, F.; Chen, A.; Argan, A.; Costa, E.; Del Monte, E.; Evangelista, Y.; Feroci, M.; Lazzarotto, F.; Lapshov, I.; Pacciani, L.; Soffitta, P.; Sabatini, S.; Vittorini, V.; Pucella, G.; Rapisarda, M.; Di Cocco, G.; Fuschino, F.; Galli, M.; Labanti, C.; Marisaldi, M.; Pellizzoni, A.; Pilia, M.; Trois, A.; Barbiellini, G.; Vallazza, E.; Longo, F.; Morselli, A.; Picozza, P.; Prest, M.; Lipari, P.; Zanello, D.; Cattaneo, P. W.; Rappoldi, A.; Colafrancesco, S.; Parmiggiani, N.; Ferrari, A.; Antonelli, A.; Giommi, P.; Salotti, L.; Valentini, G.; D'Amico, F.

    AGILE confirms the detection of enhanced gamma-ray activity from the FSRQ PKS 1313-333 (redshift z=1.210), as reported by the Fermi-LAT in ATel #8533. Integrating from 2016-01-10 02:00 UT to 2016-01-12 02:00 UT, a maximum likelihood analysis of AGILE data yields the detection of the source at a significance level of about 5 sigma with a flux of (1.6 +/- 0.6) x 10^-6 ph/cm2/s (E > 100 MeV), in agreement with the Fermi-LAT measurement.

  20. A gamma-ray flare from 3C 454.3 detected by AGILE

    NASA Astrophysics Data System (ADS)

    Munar-Adrover, P.; Piano, G.; Pittori, C.; Verrecchia, F.; Lucarelli, F.; Bulgarelli, A.; Parmiggiani, N.; Fioretti, V.; Zoli, A.; Vercellone, S.; Tavani, M.; Donnarumma, I.; Striani, E.; Minervini, G.; Cardillo, M.; Gianotti, F.; Trifoglio, M.; Giuliani, A.; Mereghetti, S.; Caraveo, P.; Perotti, F.; Chen, A.; Argan, A.; Costa, E.; Del Monte, E.; Evangelista, Y.; Feroci, M.; Lazzarotto, F.; Lapshov, I.; Pacciani, L.; Soffitta, P.; Sabatini, S.; Vittorini, V.; Pucella, G.; Rapisarda, M.; Di Cocco, G.; Fuschino, F.; Galli, M.; Labanti, C.; Marisaldi, M.; Pellizzoni, A.; Pilia, M.; Trois, A.; Barbiellini, G.; Vallazza, E.; Longo, F.; Morselli, A.; Picozza, P.; Prest, M.; Lipari, P.; Zanello, D.; Cattaneo, P. W.; Rappoldi, A.; Colafrancesco, S.; Ferrari, A.; Antonelli, A.; Giommi, P.; Salotti, L.; Valentini, G.; D'Amico, F.

    2016-06-01

    The AGILE satellite is detecting a significant enhancement in gamma-ray activity from the FSRQ 3C 454.3 since the recent ATel #9176. According to a maximum likelihood analysis of the AGILE-GRID data for the integration period between 2016-06-22 02:50:00 UT and 2016-06-24 02:50:00 UT, the flux is F(E > 100 MeV) = (1.2 +/- 0.2) x 10^-5 ph/cm^2/s; this corresponds to a flux increase of approximately a factor of 6 above the average flux during the last 6 days.

  1. SuperAGILE detection of an X-ray burst from 4U 1608-522

    NASA Astrophysics Data System (ADS)

    Del Monte, E.; Donnarumma, I.; Pacciani, L.; Evangelista, Y.; Feroci, M.; Lazzarotto, F.; Soffitta, P.; Costa, E.; Lapshov, I.; Rapisarda, M.; Giuliani, A.; Chen, A.; Mereghetti, S.; Perotti, F.; Caraveo, P.; Pellizzoni, A.; Pilia, M.; D'Ammando, F.; Vercellone, S.; Bulgarelli, A.; Gianotti, F.; Trifoglio, M.; Di Cocco, G.; Labanti, C.; Fuschino, F.; Marisaldi, M.; Galli, M.; Tavani, M.; Vittorini, V.; Striani, E.; Argan, A.; Trois, A.; Piano, G.; Sabatini, S.; Barbiellini, G.; Longo, F.; Moretti, E.; Picozza, P.; Morselli, A.; Prest, M.; Vallazza, E.; Lipari, P.; Zanello, D.; Cattaneo, P. W.; Rappoldi, A.; Pittori, C.; Verrecchia, F.; Santolamazza, P.; Lucarelli, F.; Colafrancesco, S.; Giommi, P.; Salotti, L.

    2010-03-01

    On 3 March 2010, at 06:33:25 UT SuperAGILE detected an X-ray burst with duration of about 8 s. The detection is statistically significant only in the energy band 17 - 25 keV. The burst was localized at coordinates RA=243.1868 (16h 12m 44.83s), dec=-52.4192 (-52d 25' 08.97"), with 3 arcmin error radius, in a position consistent with the neutron star transient and atoll source 4U 1608-522, that lies at a distance of about 0.4 arcmin from the SuperAGILE localization.

  2. Development of Improved Surface Integral Methods for Jet Aeroacoustic Predictions

    NASA Technical Reports Server (NTRS)

    Pilon, Anthony R.; Lyrintzis, Anastasios S.

    1997-01-01

    The accurate prediction of aerodynamically generated noise has become an important goal over the past decade. Aeroacoustics must now be an integral part of the aircraft design process. The direct calculation of aerodynamically generated noise with CFD-like algorithms is plausible. However, large computer time and memory requirements often make these predictions impractical. It is therefore necessary to separate the aeroacoustics problem into two parts, one in which aerodynamic sound sources are determined, and another in which the propagating sound is calculated. This idea is applied in acoustic analogy methods. However, in the acoustic analogy, the determination of far-field sound requires the solution of a volume integral. This volume integration again leads to impractical computer requirements. An alternative to the volume integrations can be found in the Kirchhoff method. In this method, Green's theorem for the linear wave equation is used to determine sound propagation based on quantities on a surface surrounding the source region. The change from volume to surface integrals represents a tremendous savings in the computer resources required for an accurate prediction. This work is concerned with the development of enhancements of the Kirchhoff method for use in a wide variety of aeroacoustics problems. This enhanced method, the modified Kirchhoff method, is shown to be a Green's function solution of Lighthill's equation. It is also shown rigorously to be identical to the methods of Ffowcs Williams and Hawkings. This allows for development of versatile computer codes which can easily alternate between the different Kirchhoff and Ffowcs Williams-Hawkings formulations, using the most appropriate method for the problem at hand. The modified Kirchhoff method is developed primarily for use in jet aeroacoustics predictions. Applications of the method are shown for two dimensional and three dimensional jet flows. Additionally, the enhancements are generalized so that

  3. To develop a geometric matching method for precision mold alignment

    NASA Astrophysics Data System (ADS)

    Chen, Chun-Jen; Chang, Chun-Li; Jywe, Wenyuh

    2014-09-01

    In order to develop a high accuracy optical alignment system for precision molding machine, a geometric matching method was developed in this paper. The alignment system includes 4 high magnification lenses, 4 CCD cameras and 4 LED light sources. In the precision molding machine, a bottom metal mold and a top glass mold are used to produce a micro lens. The two molds combination does not use any pin or alignment part. They only use the optical alignment system to alignment. In this optical alignment system, the off-axis alignment method was used. The alignment accuracy of the alignment system is about 0.5 μm. There are 2 cross marks on the top glass mold and 2 cross marks on the bottom metal mod. In this paper did not use edge detection to recognize the mask center because the mask easy wears when the combination times increased. Therefore, this paper develops a geometric matching method to recognize mask center.

  4. Reactions Involved in Fingerprint Development Using the Cyanoacrylate - Fuming Method

    SciTech Connect

    Lewis, L.A.

    2001-07-30

    The Learning Objective is to present the basic chemistry research findings to the forensic community regarding development of latent fingerprints using the cyanoacrylate fuming method. Chemical processes involved in the development of latent fingerprints using the cyanoacrylate fuming method have been studied, and will be presented. Two major types of latent prints have been investigated--clean (eccrine) and oily (sebaceous) prints. Scanning electron microscopy (SEM) was used as a tool for determining the morphology of the polymer developed separately on clean and oily prints after cyanoacrylate fuming. A correlation between the chemical composition of an aged latent fingerprint, prior to development, and the quality of a developed fingerprint was observed in the morphology. The moisture in the print prior to fuming was found to be a critical factor for the development of a useful latent print. In addition, the amount of time required to develop a high quality latent print was found to be minimal. The cyanoacrylate polymerization process is extremely rapid. When heat is used to accelerate the fuming process, typically a period of 2 minutes is required to develop the print. The optimum development time is dependent upon the concentration of cyanoacrylate vapors within the enclosure.

  5. PM: RESEARCH METHODS FOR PM TOXIC COMPOUNDS - PARTICLE METHODS EVALUATION AND DEVELOPMENT

    EPA Science Inventory

    The Federal Reference Method (FRM) for Particulate Matter (PM) developed by EPA's National Exposure Research Laboratory (NERL) forms the backbone of the EPA's national monitoring strategy. It is the measurement that defines attainment of the National Ambient Air Quality Standard...

  6. Recent developments in the methods of estimating shooting distance.

    PubMed

    Zeichner, Arie; Glattstein, Baruch

    2002-03-01

    A review of developments during the past 10 years in the methods of estimating shooting distance is provided. This review discusses the examination of clothing targets, cadavers, and exhibits that cannot be processed in the laboratory. The methods include visual/microscopic examinations, color tests, and instrumental analysis of the gunshot residue deposits around the bullet entrance holes. The review does not cover shooting distance estimation from shotguns that fired pellet loads. PMID:12805985

  7. Formal methods in the development of safety critical software systems

    SciTech Connect

    Williams, L.G.

    1991-11-15

    As the use of computers in critical control systems such as aircraft controls, medical instruments, defense systems, missile controls, and nuclear power plants has increased, concern for the safety of those systems has also grown. Much of this concern has focused on the software component of those computer-based systems. This is primarily due to historical experience with software systems that often exhibit larger numbers of errors than their hardware counterparts and the fact that the consequences of a software error may endanger human life, property, or the environment. A number of different techniques have been used to address the issue of software safety. Some are standard software engineering techniques aimed at reducing the number of faults in a software protect, such as reviews and walkthroughs. Others, including fault tree analysis, are based on identifying and reducing hazards. This report examines the role of one such technique, formal methods, in the development of software for safety critical systems. The use of formal methods to increase the safety of software systems is based on their role in reducing the possibility of software errors that could lead to hazards. The use of formal methods in the development of software systems is controversial. Proponents claim that the use of formal methods can eliminate errors from the software development process, and produce programs that are probably correct. Opponents claim that they are difficult to learn and that their use increases development costs unacceptably. This report discusses the potential of formal methods for reducing failures in safety critical software systems.

  8. Methods for Developing Emissions Scenarios for Integrated Assessment Models

    SciTech Connect

    Prinn, Ronald; Webster, Mort

    2007-08-20

    The overall objective of this research was to contribute data and methods to support the future development of new emissions scenarios for integrated assessment of climate change. Specifically, this research had two main objectives: 1. Use historical data on economic growth and energy efficiency changes, and develop probability density functions (PDFs) for the appropriate parameters for two or three commonly used integrated assessment models. 2. Using the parameter distributions developed through the first task and previous work, we will develop methods of designing multi-gas emission scenarios that usefully span the joint uncertainty space in a small number of scenarios. Results on the autonomous energy efficiency improvement (AEEI) parameter are summarized, an uncertainty analysis of elasticities of substitution is described, and the probabilistic emissions scenario approach is presented.

  9. A variability study of the AGILE first catalog of γ-ray sources on 2.3 years of AGILE pointed observations

    NASA Astrophysics Data System (ADS)

    Verrecchia, F.; Pittori, C.; Bulgarelli, A.; Chen, A. W.; Tavani, M.; Giommi, P.; AGILE Collaboration

    2013-01-01

    AGILE pointed observations performed from July 9, 2007 to October 30, 2009 cover a very large time interval, with a γ-ray data archive useful to perform monitoring studies of medium to high brightness γ-ray sources in the 30 MeV-50 GeV energy range. The first AGILE Gamma-Ray Imaging Detector (GRID) catalog (Pittori et al., 2009) included a significance-limited (4σ) sample of 47 sources (1AGL), detected with a conservative analysis over the first-year of operations.We present a variability study of the 1AGL sources over the complete AGILE pointed Observation Blocks (OBs) dataset.In the analysis here reported we used data obtained with an improved full Field of View (FOV) event filter, on a much larger (about 27.5 months) dataset, integrating data on the OB timescales, mostly ranging between 4 and 30 days. The data processing resulted in an improved source list as compared to the 1AGL one. We present here our results on the variability of some of these sources.

  10. Development of ultrasonic methods for the nondestructive inspection of concrete

    NASA Astrophysics Data System (ADS)

    Claytor, T. M.; Ellingson, W. A.

    1983-08-01

    Nondestructive inspection of Portland cement and refractory concrete is conducted to determine strength, thickness, presence of voids or foreign matter, presence of cracks, amount of degradation due to chemical attack, and other properties without the necessity of coring the structure (which is usually accomplished by destructively removing a sample). The state of the art of acoustic nondestructive testing methods for Portland cement and refractory concrete is reviewed. Most nondestructive work on concrete has concentrated on measuring acoustic velocity by through transmission methods. Development of a reliable pitch-catch or pulse-echo system would provide a method of measuring thickness with access from only one side of the concrete.

  11. Development of ultrasonic methods for the nondestructive inspection of concrete

    SciTech Connect

    Claytor, T.N.; Ellingson, W.A.

    1983-08-01

    Nondestructive inspection of Portland cement and refractory concrete is conducted to determine strength, thickness, presence of voids or foreign matter, presence of cracks, amount of degradation due to chemical attack, and other properties without the necessity of coring the structure (which is usually accomplished by destructively removing a sample). This paper reviews the state of the art of acoustic nondestructive testing methods for Portland cement and refractory concrete. Most nondestructive work on concrete has concentrated on measuring acoustic velocity by through transmission methods. Development of a reliable pitch-catch or pulse-echo system would provide a method of measuring thickness with access from only one side of the concrete.

  12. Development of a benchtop baking method for chemically leavened crackers. II. Validation of the method

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A benchtop baking method has been developed to predict the contribution of gluten functionality to overall flour performance for chemically leavened crackers. Using a diagnostic formula and procedure, dough rheology was analyzed to evaluate the extent of gluten development during mixing and machinin...

  13. Methods for external event screening quantification: Risk Methods Integration and Evaluation Program (RMIEP) methods development

    SciTech Connect

    Ravindra, M.K.; Banon, H.

    1992-07-01

    In this report, the scoping quantification procedures for external events in probabilistic risk assessments of nuclear power plants are described. External event analysis in a PRA has three important goals; (1) the analysis should be complete in that all events are considered; (2) by following some selected screening criteria, the more significant events are identified for detailed analysis; (3) the selected events are analyzed in depth by taking into account the unique features of the events: hazard, fragility of structures and equipment, external-event initiated accident sequences, etc. Based on the above goals, external event analysis may be considered as a three-stage process: Stage I: Identification and Initial Screening of External Events; Stage II: Bounding Analysis; Stage III: Detailed Risk Analysis. In the present report, first, a review of published PRAs is given to focus on the significance and treatment of external events in full-scope PRAs. Except for seismic, flooding, fire, and extreme wind events, the contributions of other external events to plant risk have been found to be negligible. Second, scoping methods for external events not covered in detail in the NRC`s PRA Procedures Guide are provided. For this purpose, bounding analyses for transportation accidents, extreme winds and tornadoes, aircraft impacts, turbine missiles, and chemical release are described.

  14. Methods for external event screening quantification: Risk Methods Integration and Evaluation Program (RMIEP) methods development

    SciTech Connect

    Ravindra, M.K.; Banon, H. )

    1992-07-01

    In this report, the scoping quantification procedures for external events in probabilistic risk assessments of nuclear power plants are described. External event analysis in a PRA has three important goals; (1) the analysis should be complete in that all events are considered; (2) by following some selected screening criteria, the more significant events are identified for detailed analysis; (3) the selected events are analyzed in depth by taking into account the unique features of the events: hazard, fragility of structures and equipment, external-event initiated accident sequences, etc. Based on the above goals, external event analysis may be considered as a three-stage process: Stage I: Identification and Initial Screening of External Events; Stage II: Bounding Analysis; Stage III: Detailed Risk Analysis. In the present report, first, a review of published PRAs is given to focus on the significance and treatment of external events in full-scope PRAs. Except for seismic, flooding, fire, and extreme wind events, the contributions of other external events to plant risk have been found to be negligible. Second, scoping methods for external events not covered in detail in the NRC's PRA Procedures Guide are provided. For this purpose, bounding analyses for transportation accidents, extreme winds and tornadoes, aircraft impacts, turbine missiles, and chemical release are described.

  15. FEASIBILITY OF DEVELOPING SOURCE SAMPLING METHODS FOR ASBESTOS EMISSIONS

    EPA Science Inventory

    The objective of this program was to determine the feasibility of developing methods for sampling asbestos in the emissions of major asbestos sources: (1) ore production and taconite production, (2) asbestos-cement production, (3) asbestos felt and paper production, and (4) the p...

  16. Development of a rapid detection method for Yellow Dwarf Viruses

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Barley and Cereal yellow dwarf viruses (B/CYDVs), constitute the most economically important group of oat viruses. A multiplex reverse transcription polymerase chain reaction method was developed for the simultaneous detection and discrimination of five B/CYDVs viruses. The protocol uses specific pr...

  17. EXPOSURE ASSESSMENT METHODS DEVELOPMENT PILOTS FOR THE NATIONAL CHILDREN'S STUDY

    EPA Science Inventory

    Accurate exposure classification tools are needed to link exposure with health effects. EPA began methods development pilot studies in 2000 to address general questions about exposures and outcome measures. Selected pilot studies are highlighted in this poster. The “Literature Re...

  18. DEVELOPMENT OF CRITERIA AND METHODS FOR EVALUATING TRAINER AIRCRAFT EFFECTIVENESS.

    ERIC Educational Resources Information Center

    KUSEWITT, J.B.

    THE PURPOSE OF THIS STUDY WAS TO DEVELOP A METHOD FOR DETERMINING OBJECTIVE MEASURES OF TRAINER AIRCRAFT EFFECTIVENESS TO EVALUATE PROGRAM ALTERNATIVES FOR TRAINING PILOTS FOR FLEET FIGHTER AND ATTACK-TYPE AIRCRAFT. THE TRAINING SYLLABUS WAS BASED ON AVERAGE STUDENT ABILITY. THE BASIC PROBLEM WAS TO ESTABLISH QUANTITATIVE TIME-DIFFICULTY…

  19. MONITORING METHODS DEVELOPMENT IN THE BEAUMONT-LAKE CHARLES AREA

    EPA Science Inventory

    In 1978, the U.S. Environmental Protection Agency initiated a study in the Beaumont, Texas-Lake Charles, Louisiana area (BLCA) as a preliminary step to develop, demonstrate and test methods for monitoring levels of chemicals, primarily in air and water, and to measure effects of ...

  20. Is Mixed Methods Research Used in Australian Career Development Research?

    ERIC Educational Resources Information Center

    Cameron, Roslyn

    2010-01-01

    Mixed methods research has become a substantive and growing methodological force that is growing in popularity within the human and social sciences. This article reports the findings of a study that has systematically reviewed articles from the "Australian Journal of Career Development" from 2004 to 2009. The aim of the study was to provide a…

  1. Multidisciplinary Methods in Educational Technology Research and Development

    ERIC Educational Resources Information Center

    Randolph, Justus J.

    2008-01-01

    Over the past thirty years, there has been much dialogue, and debate, about the conduct of educational technology research and development. In this brief volume, the author helps clarify that dialogue by theoretically and empirically charting the research methods used in the field and provides much practical information on how to conduct…

  2. Teaching Analytical Method Development in an Undergraduate Instrumental Analysis Course

    ERIC Educational Resources Information Center

    Lanigan, Katherine C.

    2008-01-01

    Method development and assessment, central components of carrying out chemical research, require problem-solving skills. This article describes a pedagogical approach for teaching these skills through the adaptation of published experiments and application of group-meeting style discussions to the curriculum of an undergraduate instrumental…

  3. Methods of high throughput biophysical characterization in biopharmaceutical development.

    PubMed

    Razinkov, Vladimir I; Treuheit, Michael J; Becker, Gerald W

    2013-03-01

    Discovery and successful development of biopharmaceutical products depend on a thorough characterization of the molecule both before and after formulation. Characterization of a formulated biotherapeutic, typically a protein or large peptide, requires a rigorous assessment of the molecule's physical stability. Stability of a biotherapeutic includes not only chemical stability, i.e., degradation of the molecule to form undesired modifications, but also structural stability, including the formation of aggregates. In this review, high throughput biophysical characterization techniques are described according to their specific applications during biopharmaceutical discovery, development and manufacturing. The methods presented here are classified according to these attributes, and include spectroscopic assays based on absorbance, polarization, intrinsic and extrinsic fluorescence, surface plasmon resonance instrumentation, calorimetric methods, dynamic and static light scattering techniques, several visible particle counting and sizing methods, new viscosity assay, based on light scattering and mass spectrometry. Several techniques presented here are already implemented in industry; but, many high throughput biophysical methods are still in the initial stages of implementation or even in the prototype stage. Each technique in this report is judged by the specific application of the method through the biopharmaceutical development process. PMID:22725690

  4. Global Software Development Patterns for Project Management

    NASA Astrophysics Data System (ADS)

    Välimäki, Antti; Kääriäinen, Jukka; Koskimies, Kai

    Global software development with the agile or waterfall development process has been taken into use in many companies. GSD offers benefits but also new challenges without known, documented solutions. The goal of this research is to present current best practices for GSD in the form of process patterns for project management, evaluated by using a scenario-based assessment method. The best practices have been collected from a large company operating in process automation. It is expected that the resulting pattern language helps other companies to improve their GSD processes by incorporating the patterns in the processes.

  5. Development of a practical costing method for hospitals.

    PubMed

    Cao, Pengyu; Toyabe, Shin-Ichi; Akazawa, Kouhei

    2006-03-01

    To realize an effective cost control, a practical and accurate cost accounting system is indispensable in hospitals. In traditional cost accounting systems, the volume-based costing (VBC) is the most popular cost accounting method. In this method, the indirect costs are allocated to each cost object (services or units of a hospital) using a single indicator named a cost driver (e.g., Labor hours, revenues or the number of patients). However, this method often results in rough and inaccurate results. The activity based costing (ABC) method introduced in the mid 1990s can prove more accurate results. With the ABC method, all events or transactions that cause costs are recognized as "activities", and a specific cost driver is prepared for each activity. Finally, the costs of activities are allocated to cost objects by the corresponding cost driver. However, it is much more complex and costly than other traditional cost accounting methods because the data collection for cost drivers is not always easy. In this study, we developed a simplified ABC (S-ABC) costing method to reduce the workload of ABC costing by reducing the number of cost drivers used in the ABC method. Using the S-ABC method, we estimated the cost of the laboratory tests, and as a result, similarly accurate results were obtained with the ABC method (largest difference was 2.64%). Simultaneously, this new method reduces the seven cost drivers used in the ABC method to four. Moreover, we performed an evaluation using other sample data from physiological laboratory department to certify the effectiveness of this new method. In conclusion, the S-ABC method provides two advantages in comparison to the VBC and ABC methods: (1) it can obtain accurate results, and (2) it is simpler to perform. Once we reduce the number of cost drivers by applying the proposed S-ABC method to the data for the ABC method, we can easily perform the cost accounting using few cost drivers after the second round of costing. PMID

  6. Recent developments in methods for identifying reaction coordinates

    PubMed Central

    Li, Wenjin; Ma, Ao

    2014-01-01

    In the study of rare events in complex systems with many degrees of freedom, a key element is to identify the reaction coordinates of a given process. Over recent years, a number of methods and protocols have been developed to extract the reaction coordinates based on limited information from molecular dynamics simulations. In this review, we provide a brief survey over a number of major methods developed in the past decade, some of which are discussed in greater detail, to provide an overview of the problems that are partially solved and challenges that still remain. A particular emphasis has been placed on methods for identifying reaction coordinates that are related to the committor. PMID:25197161

  7. Quality functions for requirements engineering in system development methods.

    PubMed

    Johansson, M; Timpka, T

    1996-01-01

    Based on a grounded theory framework, this paper analyses the quality characteristics for methods to be used for requirements engineering in the development of medical decision support systems (MDSS). The results from a Quality Function Deployment (QFD) used to rank functions connected to user value and a focus group study were presented to a validation focus group. The focus group studies take advantage of a group process to collect data for further analyses. The results describe factors considered by the participants as important in the development of methods for requirements engineering in health care. Based on the findings, the content which, according to the user a MDSS method should support is established. PMID:8947891

  8. Development of a transfer function method for dynamic stability measurement

    NASA Technical Reports Server (NTRS)

    Johnson, W.

    1977-01-01

    Flutter testing method based on transfer function measurements is developed. The error statistics of several dynamic stability measurement methods are reviewed. It is shown that the transfer function measurement controls the error level by averaging the data and correlating the input and output. The method also gives a direct estimate of the error in the response measurement. An algorithm is developed for obtaining the natural frequency and damping ratio of low damped modes of the system, using integrals of the transfer function in the vicinity of a resonant peak. Guidelines are given for selecting the parameters in the transfer function measurement. Finally, the dynamic stability measurement technique is applied to data from a wind tunnel test of a proprotor and wing model.

  9. Quantitative methods for analyzing cell-cell adhesion in development.

    PubMed

    Kashef, Jubin; Franz, Clemens M

    2015-05-01

    During development cell-cell adhesion is not only crucial to maintain tissue morphogenesis and homeostasis, it also activates signalling pathways important for the regulation of different cellular processes including cell survival, gene expression, collective cell migration and differentiation. Importantly, gene mutations of adhesion receptors can cause developmental disorders and different diseases. Quantitative methods to measure cell adhesion are therefore necessary to understand how cells regulate cell-cell adhesion during development and how aberrations in cell-cell adhesion contribute to disease. Different in vitro adhesion assays have been developed in the past, but not all of them are suitable to study developmentally-related cell-cell adhesion processes, which usually requires working with low numbers of primary cells. In this review, we provide an overview of different in vitro techniques to study cell-cell adhesion during development, including a semi-quantitative cell flipping assay, and quantitative single-cell methods based on atomic force microscopy (AFM)-based single-cell force spectroscopy (SCFS) or dual micropipette aspiration (DPA). Furthermore, we review applications of Förster resonance energy transfer (FRET)-based molecular tension sensors to visualize intracellular mechanical forces acting on cell adhesion sites. Finally, we describe a recently introduced method to quantitate cell-generated forces directly in living tissues based on the deformation of oil microdroplets functionalized with adhesion receptor ligands. Together, these techniques provide a comprehensive toolbox to characterize different cell-cell adhesion phenomena during development. PMID:25448695

  10. Development of quality-by-design analytical methods.

    PubMed

    Vogt, Frederick G; Kord, Alireza S

    2011-03-01

    Quality-by-design (QbD) is a systematic approach to drug development, which begins with predefined objectives, and uses science and risk management approaches to gain product and process understanding and ultimately process control. The concept of QbD can be extended to analytical methods. QbD mandates the definition of a goal for the method, and emphasizes thorough evaluation and scouting of alternative methods in a systematic way to obtain optimal method performance. Candidate methods are then carefully assessed in a structured manner for risks, and are challenged to determine if robustness and ruggedness criteria are satisfied. As a result of these studies, the method performance can be understood and improved if necessary, and a control strategy can be defined to manage risk and ensure the method performs as desired when validated and deployed. In this review, the current state of analytical QbD in the industry is detailed with examples of the application of analytical QbD principles to a range of analytical methods, including high-performance liquid chromatography, Karl Fischer titration for moisture content, vibrational spectroscopy for chemical identification, quantitative color measurement, and trace analysis for genotoxic impurities. PMID:21280050

  11. Prospects for High Energy Detection of Microquasars with the AGILE and GLAST Gamma-Ray Telescopes

    SciTech Connect

    Santolamazza, Patrizia; Pittori, Carlotta; Verrecchia, Francesco

    2007-08-21

    We estimate the sensitivities of the AGILE and GLAST {gamma}-ray experiments taking into account two cases for the galactic {gamma}-ray diffuse background (at high galactic latitude and toward the galactic center). Then we use sensitivities to estimate microquasar observability with the two experiments, assuming the {gamma}-ray emission above 100 MeV of a recent microquasar model.

  12. Are Agile and Lean Manufacturing Systems Employing Sustainability, Complexity and Organizational Learning?

    ERIC Educational Resources Information Center

    Flumerfelt, Shannon; Siriban-Manalang, Anna Bella; Kahlen, Franz-Josef

    2012-01-01

    Purpose: This paper aims to peruse theories and practices of agile and lean manufacturing systems to determine whether they employ sustainability, complexity and organizational learning. Design/methodology/approach: The critical review of the comparative operational similarities and difference of the two systems was conducted while the new views…

  13. A Quantitative Examination of Critical Success Factors Comparing Agile and Waterfall Project Management Methodologies

    ERIC Educational Resources Information Center

    Pedersen, Mitra

    2013-01-01

    This study investigated the rate of success for IT projects using agile and standard project management methodologies. Any successful project requires use of project methodology. Specifically, large projects require formal project management methodologies or models, which establish a blueprint of processes and project planning activities. This…

  14. AGILE confirmation of enhanced gamma-ray activity from the Blazar 1ES 1959+650

    NASA Astrophysics Data System (ADS)

    Lucarelli, F.; Pittori, C.; Verrecchia, F.; Bulgarelli, A.; Fioretti, V.; Zoli, A.; Piano, G.; Munar-Adrover, P.; Tavani, M.; Donnarumma, I.; Vercellone, S.; Striani, E.; Cardillo, M.; Gianotti, F.; Trifoglio, M.; Giuliani, A.; Mereghetti, S.; Caraveo, P.; Perotti, F.; Chen, A.; Argan, A.; Costa, E.; Del Monte, E.; Evangelista, Y.; Feroci, M.; Lazzarotto, F.; Lapshov, I.; Pacciani, L.; Soffitta, P.; Sabatini, S.; Vittorini, V.; Pucella, G.; Rapisarda, M.; Di Cocco, G.; Fuschino, F.; Galli, M.; Labanti, C.; Marisaldi, M.; Pellizzoni, A.; Pilia, M.; Trois, A.; Barbiellini, G.; Vallazza, E.; Longo, F.; Morselli, A.; Picozza, P.; Prest, M.; Lipari, P.; Zanello, D.; Cattaneo, P. W.; Rappoldi, A.; Colafrancesco, S.; Parmiggiani, N.; Ferrari, A.; Antonelli, A.; Giommi, P.; Salotti, L.; Valentini, G.; D'Amico, F.

    2016-06-01

    Following ATel #9148, reporting multi-wavelength activity from the BL Lac type blazar 1ES 1959+650, AGILE also detects increased gamma-ray emission above 100 MeV from a position compatible with this BL Lac source.

  15. Promising Practices in Professional Growth & Support: "Case Study of Agile Mind"

    ERIC Educational Resources Information Center

    Education Resource Strategies, 2013

    2013-01-01

    Four organizations with promising practices in teacher Professional Growth & Support have significantly raised outcomes for low-income students. The charter management networks, Achievement First and Aspire Public Schools, and the two reform organizations, Teach Plus and Agile Mind, have successfully increased student achievement with a…

  16. Lean vs Agile in the Context of Complexity Management in Organizations

    ERIC Educational Resources Information Center

    Putnik, Goran D.; Putnik, Zlata

    2012-01-01

    Purpose: The objective of this paper is to provide a deeper insight into the relationship of the issue "lean vs agile" in order to inform managers towards more coherent decisions especially in a dynamic, unpredictable, uncertain, non-linear environment. Design/methodology/approach: The methodology is an exploratory study based on secondary data…

  17. Strength and Agility Training in Adolescents with Down Syndrome: A Randomized Controlled Trial

    ERIC Educational Resources Information Center

    Lin, Hsiu-Ching; Wuang, Yee-Pay

    2012-01-01

    The purpose of this study was to investigate the effects of a proposed strength and agility training program of adolescents with Down syndrome. Ninety-two adolescents were recruited and evenly randomized to two intervention groups (exercise group vs. control group). The mean age for the exercise and the control group was 10.6 plus or minus 3.2 and…

  18. Comparison of Speed, Agility, Anaerobic Strength and Anthropometric Characteristics in Male Football and Futsal Players

    ERIC Educational Resources Information Center

    Kartal, Resat

    2016-01-01

    The purpose of this study is to compare speed, agility, anaerobic strength and some anthropometric characteristics in male football and futsal players. The sample of the study is composed of male futsal team players of Aydin Adnan Menderes University (19-24 aged) (n = 12) and Aydin Merkez Yeniköy Football Club players (19-24 aged) (n = 12). Within…

  19. Quantifying nonhomogeneous colors in agricultural materials part I: method development.

    PubMed

    Balaban, M O

    2008-11-01

    Measuring the color of food and agricultural materials using machine vision (MV) has advantages not available by other measurement methods such as subjective tests or use of color meters. The perception of consumers may be affected by the nonuniformity of colors. For relatively uniform colors, average color values similar to those given by color meters can be obtained by MV. For nonuniform colors, various image analysis methods (color blocks, contours, and "color change index"[CCI]) can be applied to images obtained by MV. The degree of nonuniformity can be quantified, depending on the level of detail desired. In this article, the development of the CCI concept is presented. For images with a wide range of hue values, the color blocks method quantifies well the nonhomogeneity of colors. For images with a narrow hue range, the CCI method is a better indicator of color nonhomogeneity. PMID:19021817

  20. REVIEW: Development of methods for body composition studies

    NASA Astrophysics Data System (ADS)

    Mattsson, Sören; Thomas, Brian J.

    2006-07-01

    This review is focused on experimental methods for determination of the composition of the human body, its organs and tissues. It summarizes the development and current status of fat determinations from body density, total body water determinations through the dilution technique, whole and partial body potassium measurements for body cell mass estimates, in vivo neutron activation analysis for body protein measurements, dual-energy absorptiometry (DEXA), computed tomography (CT) and magnetic resonance imaging (MRI, fMRI) and spectroscopy (MRS) for body composition studies on tissue and organ levels, as well as single- and multiple-frequency bioimpedance (BIA) and anthropometry as simple easily available methods. Methods for trace element analysis in vivo are also described. Using this wide range of measurement methods, together with gradually improved body composition models, it is now possible to quantify a number of body components and follow their changes in health and disease.

  1. Development of Integration and Adjustment Method for Sequential Range Images

    NASA Astrophysics Data System (ADS)

    Nagara, K.; Fuse, T.

    2015-05-01

    With increasing widespread use of three-dimensional data, the demand for simplified data acquisition is also increasing. The range camera, which is a simplified sensor, can acquire a dense-range image in a single shot; however, its measuring coverage is narrow and its measuring accuracy is limited. The former drawback had be overcome by registering sequential range images. This method, however, assumes that the point cloud is error-free. In this paper, we develop an integration method for sequential range images with error adjustment of the point cloud. The proposed method consists of ICP (Iterative Closest Point) algorithm and self-calibration bundle adjustment. The ICP algorithm is considered an initial specification for the bundle adjustment. By applying the bundle adjustment, coordinates of the point cloud are modified and the camera poses are updated. Through experimentation on real data, the efficiency of the proposed method has been confirmed.

  2. Arsenic extraction and speciation in plants: Method comparison and development.

    PubMed

    Zhao, Di; Li, Hong-Bo; Xu, Jia-Yi; Luo, Jun; Ma, Lena Qiying

    2015-08-01

    We compared four methods to extract arsenic (As) from three different plants containing different As levels for As speciation with the goal of developing a more efficient method, i.e., As-hyperaccumulator Pteris vittata at 459-7714mgkg(-1), rice seedling at 53.4-574mgkg(-1), and tobacco leaf at 0.32-0.35mgkg(-1). The four methods included heating with dilute HNO3, and sonication with phosphate buffered solution, methanol/water, and ethanol/water, with As being analyzed using high-performance liquid chromatography coupled with inductively-coupled plasma mass spectrometry (HPLC-ICP-MS). Among the four methods, the ethanol/water method produced the most satisfactory extraction efficiency (~80% for the roots and >85% for the fronds) without changing As species based on P. vittata. The lower extraction efficiency from P. vittata roots was attributed to its dominance by arsenate (82%) while arsenite dominated in the fronds (89%). The ethanol/water method used sample:solution ratio of 1:200 (0.05g:10mL) with 50% ethanol and 2h sonication. Based on different extraction times (0.5-2h), ethanol concentrations (25-100%) and sample:solution ratios (1:50-1:300), the optimized ethanol/water method used less ethanol (25%) and time (0.5h for the fronds and 2h for the roots). Satisfactory extraction was also obtained for tobacco leaf (78-92%) and rice seedlings (~70%) using the optimized method, which was better than the other three methods. Based on satisfactory extraction efficiency with little change in As species during extraction from three plants containing different As levels, the optimized method has the potential to be used for As speciation in other plants. PMID:25863504

  3. Development of nondestructive evaluation methods for structural ceramics

    SciTech Connect

    Ellingson, W.A.; Koehl, R.D.; Wilson, J.A.; Stuckey, J.B.; Engel, H.P. |

    1996-04-01

    Nondestructive evaluation (NDE) methods using three-dimensional microfocus X-ray computed tomographic imaging (3DXCT) were employed to map axial and radial density variations in hot-gas filters and heat exchanger tubes. 3D XCT analysis was conducted on (a) two 38-mm-OD, 6.5-mm wall, SiC/SiC heat exchanger tubes infiltrated by CVI; (b) eight 10 cm diam. oxide/oxide heat exchanger tubes; and (c) one 26-cm-long Nextel fiber/SiC matrix hot-gas filter. The results show that radial and axial density uniformity as well as porosity, can be assessed by 3D XCT. NDE methods are also under development to assess thermal barrier coatings which are under development as methods to protect gas-turbine first-stage hot section metallic substrates. Further, because both shop and field joining of CFCC materials will be necessary, work is now beginning on development of NDE methods for joining.

  4. Organic analysis and analytical methods development: FY 1995 progress report

    SciTech Connect

    Clauss, S.A.; Hoopes, V.; Rau, J.

    1995-09-01

    This report describes the status of organic analyses and developing analytical methods to account for the organic components in Hanford waste tanks, with particular emphasis on tanks assigned to the Flammable Gas Watch List. The methods that have been developed are illustrated by their application to samples obtained from Tank 241-SY-103 (Tank 103-SY). The analytical data are to serve as an example of the status of methods development and application. Samples of the convective and nonconvective layers from Tank 103-SY were analyzed for total organic carbon (TOC). The TOC value obtained for the nonconvective layer using the hot persulfate method was 10,500 {mu}g C/g. The TOC value obtained from samples of Tank 101-SY was 11,000 {mu}g C/g. The average value for the TOC of the convective layer was 6400 {mu}g C/g. Chelator and chelator fragments in Tank 103-SY samples were identified using derivatization. gas chromatography/mass spectrometry (GC/MS). Organic components were quantified using GC/flame ionization detection. Major components in both the convective and nonconvective-layer samples include ethylenediaminetetraacetic acid (EDTA), nitrilotriacetic acid (NTA), succinic acid, nitrosoiminodiacetic acid (NIDA), citric acid, and ethylenediaminetriacetic acid (ED3A). Preliminary results also indicate the presence of C16 and C18 carboxylic acids in the nonconvective-layer sample. Oxalic acid was one of the major components in the nonconvective layer as determined by derivatization GC/flame ionization detection.

  5. Analysis of VLF signals associated to AGILE Terrestrial Gamma-ray Flashes detected over Central America

    NASA Astrophysics Data System (ADS)

    Marisaldi, Martino; Lyu, Fanchao; Cummer, Steven; Ursi, Alessandro

    2016-04-01

    Analysis of radio signals detected on ground and associated to Terrestrial Gamma-ray Flashes (TGFs) have proven to be a successful tool to extract information on the TGF itself and the possible associated lightning process. Triangulation of Very Low Frequency (VLF) signals by means of the Time Of Arrival technique provides TGF location with few km accuracy. The AGILE satellite is routinely observing TGFs on a narrow band across the Equator, limited by the small satellite orbital inclination (2.5°). However, until recently it was not possible to provide firm associations between AGILE TGFs and radio signals, because of two main limiting factors. First, dead-time effects led to a bias towards long duration events in AGILE TGF sample, which are less likely associated to strong radio pulses. In addition, most VLF detection networks are less sensitive along the equatorial region. Since the end of March 2015 a major change in the AGILE MiniCalorimeter instrument configuration resulted in a ten fold increase in TGF detection rate, and in the detection of events as short as 20 microseconds. 14% of the events in the new sample resulted simultaneous (within 200 microseconds) to sferics detected by the World Wide Lightning Location Network (WWLLN), therefore a source localisation is available for these events. We present here the first analysis of VLF waveforms associated to AGILE TGFs observed above Central America, detected by magnetic field sensors deployed in Puerto Rico. Among the seven TGFs with a WWLLN location at a distance lower than 10000 km from the sensors, four of them have detectable signals. These events are the closest to the sensors, with distance less than 7500 km. We present here the properties of these TGFs and the characteristics of the associated radio waveforms.

  6. Analytical Failure Prediction Method Developed for Woven and Braided Composites

    NASA Technical Reports Server (NTRS)

    Min, James B.

    2003-01-01

    Historically, advances in aerospace engine performance and durability have been linked to improvements in materials. Recent developments in ceramic matrix composites (CMCs) have led to increased interest in CMCs to achieve revolutionary gains in engine performance. The use of CMCs promises many advantages for advanced turbomachinery engine development and may be especially beneficial for aerospace engines. The most beneficial aspects of CMC material may be its ability to maintain its strength to over 2500 F, its internal material damping, and its relatively low density. Ceramic matrix composites reinforced with two-dimensional woven and braided fabric preforms are being considered for NASA s next-generation reusable rocket turbomachinery applications (for example, see the preceding figure). However, the architecture of a textile composite is complex, and therefore, the parameters controlling its strength properties are numerous. This necessitates the development of engineering approaches that combine analytical methods with limited testing to provide effective, validated design analyses for the textile composite structures development.

  7. Southern Argentina Agile Meteor Radar: Initial assessment of gravity wave momentum fluxes

    NASA Astrophysics Data System (ADS)

    Fritts, D. C.; Janches, D.; Hocking, W. K.

    2010-10-01

    The Southern Argentina Agile Meteor Radar (SAAMER) was installed on Tierra del Fuego (53.8°S) in May 2008 and has been operational since that time. This paper describes tests of the SAAMER ability to measure gravity wave momentum fluxes and applications of this capability during different seasons. Test results for specified mean, tidal, and gravity wavefields, including tidal amplitudes and gravity wave momentum fluxes varying strongly with altitude and/or time, suggest that the distribution of meteors throughout the diurnal cycle and averaged over a month allows characterization of both monthly mean profiles and diurnal variations of the gravity wave momentum fluxes. Applications of the same methods for real data suggest confidence in the monthly mean profiles and the composite day diurnal variations of gravity wave momentum fluxes at altitudes where meteor counts are sufficient to yield good statistical fits to the data. Monthly mean zonal winds and gravity wave momentum fluxes exhibit anticorrelations consistent with those seen at other midlatitude and high-latitude radars during austral spring and summer, when no strong local gravity wave sources are apparent. When stratospheric variances are significantly enhanced over the Drake Passage “hot spot” during austral winter, however, MLT winds and momentum fluxes over SAAMER exhibit very different correlations that suggest that MLT dynamics are strongly influenced by strong local gravity wave sources within this “hot spot.” SAAMER measurements of mean zonal and meridional winds at these times and their differences from measurements at a conjugate site provide further support for the unusual momentum flux measurements.

  8. Development of a spatial method for weed detection and localization

    NASA Astrophysics Data System (ADS)

    Vioix, Jean-Baptiste; Douzals, Jean-Paul; Truchetet, Fréd. éric

    2004-02-01

    This paper presents an algorithm specifically developed for filtering low frequency signals. The application is related to weed detection into aerial images where crop lines are detected as repetitive structures. Theoretical bases of this work are presented first. Then, two methods are compared to select low frequency signals and their limitations are described. A decomposition based on wavelet packet is used to combine advantages of both methods. This algorithm allows a high selectivity of low frequency signals with an interesting computation time. At last, a complete algorithm for weed/crop classification is explained and a few results are shown.

  9. Control of irradiated food: Recent developments in analytical detection methods.

    NASA Astrophysics Data System (ADS)

    Delincée, H.

    1993-07-01

    An overview of recent international efforts, i.e. programmes of "ADMIT" (FAO/IAEA) and of BCR (EC) towards the development of analytical detection methods for radiation processed foods will be given. Some larger collaborative studies have already taken place, e.g. ESR of bones from chicken, prok, beef, frog legs and fish, thermoluminescence of insoluble minerals isolated from herbs and spices, GC analysis of long-chain hydrocarbons derived from the lipid fraction of chicken and other meats, and the microbiological APC/DEFT procedure for spices. These methods could soon be implemented in international standard protocols.

  10. Development of target allocation methods for LAMOST focal plate

    NASA Astrophysics Data System (ADS)

    Yuan, Hailong; Zhang, Haotong; Zhang, Yanxia; Lei, Yajuan; Dong, Yiqiao

    2014-01-01

    We first introduce the primary target allocation requirements and restrictions for the parallel control multiple fiber system, which is used in the LAMOST spectroscopic survey. The fiber positioner anti-collision model is imported. Then several target allocation methods and features are discussed in detail, including a network flow algorithm, high priority for fiber unit holding less target number, target allocation algorithm for groups, target allocation method for add-ons and target reallocation. Their virtues and weaknesses are analyzed for various kinds of scientific research situations. Furthermore an optimization concept using the Simulate Anneal Arithmetic (SAA) is developed to improve the fiber utilizing efficiency.

  11. A newly developed wrapping method for scintillator detectors

    NASA Astrophysics Data System (ADS)

    Stuhl, L.; Krasznahorkay, A.; Csatlós, M.; Algora, A.; Gulyás, J.; Kalinka, G.; Kertész, Zs I.; Timár, J.

    2016-01-01

    A neutron spectrometer, the European Low-Energy Neutron Spectrometer (ELENS), has been constructed to study exotic nuclei in inverse kinematics experiments. The spectrometer consisting of scintillator bars can be used in the neutron energy range of 100 keV to 10 MeV. To increase the light collection efficiency a special wrapping method was developed for each bars of ELENS. By using the specially heat treated reflector foil 15-20% better light collection is available. The development of wrapping process, the results of the test experiments are also presented.

  12. Internal R and D task summary report: analytical methods development

    SciTech Connect

    Schweighardt, F.K.

    1983-07-01

    International Coal Refining Company (ICRC) conducted two research programs to develop analytical procedures for characterizing the feed, intermediates,and products of the proposed SRC-I Demonstration Plant. The major conclusion is that standard analytical methods must be defined and assigned statistical error limits of precision and reproducibility early in development. Comparing all SRC-I data or data from different processes is complex and expensive if common data correlation procedures are not followed. ICRC recommends that processes be audited analytically and statistical analyses generated as quickly as possible, in order to quantify process-dependent and -independent variables. 16 references, 10 figures, 20 tables.

  13. Interferometric Meteor Head Echo Observations using the Southern Argentina Agile Meteor Radar (SAAMER)

    NASA Technical Reports Server (NTRS)

    Janches, D.; Hocking, W.; Pifko, S.; Hormaechea, J. L.; Fritts, D. C.; Brunini, C; Michell, R.; Samara, M.

    2013-01-01

    A radar meteor echo is the radar scattering signature from the free-electrons in a plasma trail generated by entry of extraterrestrial particles into the atmosphere. Three categories of scattering mechanisms exist: specular, nonspecular trails, and head-echoes. Generally, there are two types of radars utilized to detect meteors. Traditional VHF meteor radars (often called all-sky1radars) primarily detect the specular reflection of meteor trails traveling perpendicular to the line of sight of the scattering trail, while High Power and Large Aperture (HPLA) radars efficiently detect meteor head-echoes and, in some cases, non-specular trails. The fact that head-echo measurements can be performed only with HPLA radars limits these studies in several ways. HPLA radars are very sensitive instruments constraining the studies to the lower masses, and these observations cannot be performed continuously because they take place at national observatories with limited allocated observing time. These drawbacks can be addressed by developing head echo observing techniques with modified all-sky meteor radars. In addition, the fact that the simultaneous detection of all different scattering mechanisms can be made with the same instrument, rather than requiring assorted different classes of radars, can help clarify observed differences between the different methodologies. In this study, we demonstrate that such concurrent observations are now possible, enabled by the enhanced design of the Southern Argentina Agile Meteor Radar (SAAMER) deployed at the Estacion Astronomica Rio Grande (EARG) in Tierra del Fuego, Argentina. The results presented here are derived from observations performed over a period of 12 days in August 2011, and include meteoroid dynamical parameter distributions, radiants and estimated masses. Overall, the SAAMER's head echo detections appear to be produced by larger particles than those which have been studied thus far using this technique.

  14. An agile acquisition decision-support workbench for evaluating ISR effectiveness

    NASA Astrophysics Data System (ADS)

    Stouch, Daniel W.; Champagne, Valerie; Mow, Christopher; Rosenberg, Brad; Serrin, Joshua

    2011-06-01

    The U.S. Air Force is consistently evolving to support current and future operations through the planning and execution of intelligence, surveillance and reconnaissance (ISR) missions. However, it is a challenge to maintain a precise awareness of current and emerging ISR capabilities to properly prepare for future conflicts. We present a decisionsupport tool for acquisition managers to empirically compare ISR capabilities and approaches to employing them, thereby enabling the DoD to acquire ISR platforms and sensors that provide the greatest return on investment. We have developed an analysis environment to perform modeling and simulation-based experiments to objectively compare alternatives. First, the analyst specifies an operational scenario for an area of operations by providing terrain and threat information; a set of nominated collections; sensor and platform capabilities; and processing, exploitation, and dissemination (PED) capacities. Next, the analyst selects and configures ISR collection strategies to generate collection plans. The analyst then defines customizable measures of effectiveness or performance to compute during the experiment. Finally, the analyst empirically compares the efficacy of each solution and generates concise reports to document their conclusions, providing traceable evidence for acquisition decisions. Our capability demonstrates the utility of using a workbench environment for analysts to design and run experiments. Crafting impartial metrics enables the acquisition manager to focus on evaluating solutions based on specific military needs. Finally, the metric and collection plan visualizations provide an intuitive understanding of the suitability of particular solutions. This facilitates a more agile acquisition strategy that handles rapidly changing technology in response to current military needs.

  15. Development of an in vitro cloning method for Cowdria ruminantium.

    PubMed Central

    Perez, J M; Martinez, D; Debus, A; Sheikboudou, C; Bensaid, A

    1997-01-01

    Cowdria ruminantium is a tick-borne rickettsia which causes severe disease in ruminants. All studies with C. ruminantium reported so far were carried out with stocks consisting of infective blood collected from reacting animals or from the same stocks propagated in vitro. Cloned isolates are needed to conduct studies on immune response of the host, on genetic diversity of the parasite, and on mechanisms of attenuation and the development of vaccines. A method of cloning based on the particular chlamydia life cycle of Cowdria was developed. Instead of cloning extracellular elementary bodies, it appeared more convenient to clone endothelial cells infected by one morula resulting from the infection of the cell by one elementary body of Cowdria. Two hundred and sixteen clones were obtained by limiting dilution of infected cells. The method was experimentally validated by comparing randomly amplified polymorphic DNA fingerprints from individual clones obtained from endothelial cell cultures coinfected with two different stocks of C. ruminantium. PMID:9302217

  16. Development of motion control method for laser soldering process

    SciTech Connect

    Yerganian, S.S.

    1997-05-01

    Development of a method to generate the motion control data for sealing an electronic housing using laser soldering is described. The motion required to move the housing under the laser is a nonstandard application and was performed with a four-axis system using the timed data streaming mode capabilities of a Compumotor AT6400 indexer. A Microsoft Excel 5.0 spreadsheet (named Israuto.xls) was created to calculate the movement of the part under the laser, and macros were written into the spreadsheet to allow the user to easily create this data. A data verification method was developed for simulating the motion data. The geometry of the assembly was generated using Parametric Technology Corporation Pro/E version 15. This geometry was then converted using Pro/DADS version 3.1 from Computer Aided Design Software Inc. (CADSI), and the simulation was carried out using DADS version 8.0 from CADSI.

  17. In silico machine learning methods in drug development.

    PubMed

    Dobchev, Dimitar A; Pillai, Girinath G; Karelson, Mati

    2014-01-01

    Machine learning (ML) computational methods for predicting compounds with pharmacological activity, specific pharmacodynamic and ADMET (absorption, distribution, metabolism, excretion and toxicity) properties are being increasingly applied in drug discovery and evaluation. Recently, machine learning techniques such as artificial neural networks, support vector machines and genetic programming have been explored for predicting inhibitors, antagonists, blockers, agonists, activators and substrates of proteins related to specific therapeutic targets. These methods are particularly useful for screening compound libraries of diverse chemical structures, "noisy" and high-dimensional data to complement QSAR methods, and in cases of unavailable receptor 3D structure to complement structure-based methods. A variety of studies have demonstrated the potential of machine-learning methods for predicting compounds as potential drug candidates. The present review is intended to give an overview of the strategies and current progress in using machine learning methods for drug design and the potential of the respective model development tools. We also regard a number of applications of the machine learning algorithms based on common classes of diseases. PMID:25262800

  18. Development of Nondestructive Inspection Methods for Composite Repair

    NASA Astrophysics Data System (ADS)

    Hsu, D. K.; Barnard, D. J.; Peters, J. J.; Dayal, V.

    2003-03-01

    This paper describes the development and implementation of two complementary nondestructive inspection methods for repairs made on aircraft composite honeycomb structures: computer aided tap testing (CATT) and air-coupled ultrasonic testing (AC-UT). The CATT, being a semi-automated and quantitative technique, is exploited to map out the interior conditions of a repaired part. The same repair is also imaged with air-coupled ultrasound and both compared with the results from destructive sectioning.

  19. Lattice Boltzmann method on unstructured grids: further developments.

    PubMed

    Ubertini, S; Bella, G; Succi, S

    2003-07-01

    We discuss further developments of the finite-volume lattice Boltzmann formulation on unstructured grids. It is shown that the method tolerates significant grid distortions without showing any appreciable numerical viscosity effects at second order in the mesh size. A theoretical argument of plausibility for such a property is presented. In addition, a set of boundary conditions which permit to handle flows with open boundaries is also introduced and numerically demonstrated for the case of channel flows and driven cavity flows. PMID:12935281

  20. Attitude Estimation for Unresolved Agile Space Objects with Shape Model Uncertainty

    NASA Astrophysics Data System (ADS)

    Holzinger, M.; Alfriend, K. T.; Wetterer, C. J.; Luu, K. K.; Sabol, C.; Hamada, K.; Harms, A.

    2012-09-01

    The increasing number of manufactured on-orbit objects as well as improving sensor capabilities indicate that the number of trackable objects will likely exceed 100,000 within the next several years. Characterizing the large population of non-spatially resolved active spacecraft, retired spacecraft, rocket bodies, debris, and High Area to Mass Ratio (HAMR) objects necessarily involves both attitude and shape estimation. While spatially unresolved space objects cannot be directly imaged, attitude and shape may be inferred by carefully examining their lightcurves. Lightcurves are temporally-resolved sequences of photometric intensity measurements over one or more bandwidths. Because the observable reflected light from an unresolved space object is a strong function of both its shape and attitude, estimating these parameters using lightcurves can provide an avenue to determine both space object attitude and shape. This problem is traditionally called `lightcurve inversion.' While lightcurves have been used for 25 years to characterize spin states and shapes of asteroids, estimating the attitude states and shapes of manufactured space objects involves a new set of challenges. New challenges addressed in this paper are 1) An active (agile) space object is often directly controlling its attitude, meaning that torques acting on the space object are not necessarily zero (non-homogeneous motion) and mass properties may not be known, 2) Shape models must often be estimated, and as such contain errors that need to be accounted for in the measurement function, 3) Dynamics and measurement functions are excessively nonlinear, and manufactured space objects may be quite symmetric about at least one axis of rotation/reflection. This can lead to multiple possible attitude estimate solutions and suggests the use of non-Gaussian estimation approaches. Agile space objects (those that can actively maneuver) pose new problems to lightcurve inversion efforts to estimate attitude. Because

  1. Development of gait segmentation methods for wearable foot pressure sensors.

    PubMed

    Crea, S; De Rossi, S M M; Donati, M; Reberšek, P; Novak, D; Vitiello, N; Lenzi, T; Podobnik, J; Munih, M; Carrozza, M C

    2012-01-01

    We present an automated segmentation method based on the analysis of plantar pressure signals recorded from two synchronized wireless foot insoles. Given the strict limits on computational power and power consumption typical of wearable electronic components, our aim is to investigate the capability of a Hidden Markov Model machine-learning method, to detect gait phases with different levels of complexity in the processing of the wearable pressure sensors signals. Therefore three different datasets are developed: raw voltage values, calibrated sensor signals and a calibrated estimation of total ground reaction force and position of the plantar center of pressure. The method is tested on a pool of 5 healthy subjects, through a leave-one-out cross validation. The results show high classification performances achieved using estimated biomechanical variables, being on average the 96%. Calibrated signals and raw voltage values show higher delays and dispersions in phase transition detection, suggesting a lower reliability for online applications. PMID:23367055

  2. Viscous wing theory development. Volume 1: Analysis, method and results

    NASA Technical Reports Server (NTRS)

    Chow, R. R.; Melnik, R. E.; Marconi, F.; Steinhoff, J.

    1986-01-01

    Viscous transonic flows at large Reynolds numbers over 3-D wings were analyzed using a zonal viscid-inviscid interaction approach. A new numerical AFZ scheme was developed in conjunction with the finite volume formulation for the solution of the inviscid full-potential equation. A special far-field asymptotic boundary condition was developed and a second-order artificial viscosity included for an improved inviscid solution methodology. The integral method was used for the laminar/turbulent boundary layer and 3-D viscous wake calculation. The interaction calculation included the coupling conditions of the source flux due to the wing surface boundary layer, the flux jump due to the viscous wake, and the wake curvature effect. A method was also devised incorporating the 2-D trailing edge strong interaction solution for the normal pressure correction near the trailing edge region. A fully automated computer program was developed to perform the proposed method with one scalar version to be used on an IBM-3081 and two vectorized versions on Cray-1 and Cyber-205 computers.

  3. Development and validation of an high-performance liquid chromatography-diode array detector method for the simultaneous determination of six phenolic compounds in abnormal savda munziq decoction

    PubMed Central

    Tian, Shuge; Liu, Wenxian; Liu, Feng; Zhang, Xuejia; Upur, Halmuart

    2015-01-01

    Aims: Given the high-effectiveness and low-toxicity of abnormal savda munziq (ASMQ), its herbal formulation has long been used in traditional Uyghur medicine to treat complex diseases, such as cancer, diabetes, and cardiovascular diseases. Settings and Design: ASMQ decoction by reversed-phase high-performance liquid chromatography coupled with a diode array detector was successfully developed for the simultaneous quality assessment of gallic acid, protocatechuic acid, caffeic acid, rutin, rosmarinic acid, and luteolin. The six phenolic compounds were separated on an Agilent TC-C18 reversed-phase analytical column (4.6 × 250 mm, 5 μm) by gradient elution using 0.3% aqueous formic acid (v/v) and 0.3% methanol formic acid (v/v) at 1.0 mL/min. Materials and Methods: The plant material was separately ground and mixed at the following ratios (10): Cordia dichotoma (10.6), Anchusa italic (10.6), Euphorbia humifusa (4.9), Adiantum capillus-veneris (4.9), Ziziphus jujube (4.9), Glycyrrhiza uralensis (7.1), Foeniculum vulgare (4.9), Lavandula angustifolia (4.9), Dracocephalum moldavica L. (4.9), and Alhagi pseudoalhagi (42.3). Statistical Analysis Used: The precisions of all six compounds were <0.60%, and the average recoveries ranged from 99.39% to 104.85%. Highly significant linear correlations were found between component concentrations and specific chromatographic peak areas (R2 > 0.999). Results: The proposed method was successfully applied to determine the levels of six active components in ASMQ. Conclusions: Given the simplicity, precision, specificity, and sensitivity of the method, it can be utilized as a quality control approach to simultaneously determining the six phenolic compounds in AMSQ. PMID:25709227

  4. Development of Analysis Methods for Designing with Composites

    NASA Technical Reports Server (NTRS)

    Madenci, E.

    1999-01-01

    The project involved the development of new analysis methods to achieve efficient design of composite structures. We developed a complex variational formulation to analyze the in-plane and bending coupling response of an unsymmetrically laminated plate with an elliptical cutout subjected to arbitrary edge loading as shown in Figure 1. This formulation utilizes four independent complex potentials that satisfy the coupled in-plane and bending equilibrium equations, thus eliminating the area integrals from the strain energy expression. The solution to a finite geometry laminate under arbitrary loading is obtained by minimizing the total potential energy function and solving for the unknown coefficients of the complex potentials. The validity of this approach is demonstrated by comparison with finite element analysis predictions for a laminate with an inclined elliptical cutout under bi-axial loading.The geometry and loading of this laminate with a lay-up of [-45/45] are shown in Figure 2. The deformed configuration shown in Figure 3 reflects the presence of bending-stretching coupling. The validity of the present method is established by comparing the out-of-plane deflections along the boundary of the elliptical cutout from the present approach with those of the finite element method. The comparison shown in Figure 4 indicates remarkable agreement. The details of this method are described in a manuscript by Madenci et al. (1998).

  5. New developments in the multiscale hybrid energy density computational method

    NASA Astrophysics Data System (ADS)

    Min, Sun; Shanying, Wang; Dianwu, Wang; Chongyu, Wang

    2016-01-01

    Further developments in the hybrid multiscale energy density method are proposed on the basis of our previous papers. The key points are as follows. (i) The theoretical method for the determination of the weight parameter in the energy coupling equation of transition region in multiscale model is given via constructing underdetermined equations. (ii) By applying the developed mathematical method, the weight parameters have been given and used to treat some problems in homogeneous charge density systems, which are directly related with multiscale science. (iii) A theoretical algorithm has also been presented for treating non-homogeneous systems of charge density. The key to the theoretical computational methods is the decomposition of the electrostatic energy in the total energy of density functional theory for probing the spanning characteristic at atomic scale, layer by layer, by which the choice of chemical elements and the defect complex effect can be understood deeply. (iv) The numerical computational program and design have also been presented. Project supported by the National Basic Research Program of China (Grant No. 2011CB606402) and the National Natural Science Foundation of China (Grant No. 51071091).

  6. The ReaxFF method - new applications and developments

    NASA Astrophysics Data System (ADS)

    van Duin, Adri

    The ReaxFF method provides a highly transferable simulation method for atomistic scale simulations on chemical reactions at the nanosecond and nanometer scale. It combines concepts of bond-order based potentials with a polarizable charge distribution. Since it initial development for hydrocarbons in 2001, we have found that this concept is transferable to applications to elements all across the periodic table, including all first row elements, metals, ceramics and ionic materials. For all these elements and associated materials we have demonstrated that ReaxFF can reproduce quantum mechanics-based structures, reaction energies and reaction barriers with reasonable accuracy, enabling the method to predict reaction kinetics in complicated, multi-material environments at a relatively modest computational expense. This presentation will describe the current concepts of the ReaxFF method, the current status of the various ReaxFF codes, including parallel implementations and recently developed hybrid Grand Canonical Monte Carlo options - which significantly increase its application areas. Also, we will present and overview of recent applications to a range of materials of increasing complexity, with a focus on applications to combustion, biomaterials, batteries, tribology and catalysis.

  7. Development of acoustic sniper localization methods and models

    NASA Astrophysics Data System (ADS)

    Grasing, David; Ellwood, Benjamin

    2010-04-01

    A novel examination of a method capable of providing situational awareness of sniper fire from small arms fire is presented. Situational Awareness (SA) information is extracted by exploiting two distinct sounds created by small arms discharge: the muzzle blast (created when the bullet leaves the barrel of the gun) and the shockwave (sound created by a supersonic bullet). The direction of arrival associated with the muzzle blast will always point in the direction of the shooter. Range can be estimated from the muzzle blast alone, however at greater distances geometric dilution of precision will make obtaining accurate range estimates difficult. To address this issue, additional information obtained from the shockwave is utilized in order to estimate range to shooter. The focus of the paper is the development of a shockwave propagation model, the development of ballistics models (based off empirical measurements), and the subsequent application towards methods of determining shooter position. Knowledge of the rounds ballistics is required to estimate range to shooter. Many existing methods rely on extracting information from the shockwave in an attempt to identify the round type and thus the ballistic model to use ([1]). It has been our experience that this information becomes unreliable at greater distances or in high noise environments. Our method differs from existing solutions in that classification of the round type is not required, thus making the proposed solution more robust. Additionally, we demonstrate that sufficient accuracy can be achieved without the need to classify the round.

  8. Accuracy of age estimation of radiographic methods using developing teeth.

    PubMed

    Maber, M; Liversidge, H M; Hector, M P

    2006-05-15

    Developing teeth are used to assess maturity and estimate age in a number of disciplines, however the accuracy of different methods has not been systematically investigated. The aim of this study was to determine the accuracy of several methods. Tooth formation was assessed from radiographs of healthy children attending a dental teaching hospital. The sample was 946 children (491 boys, 455 girls, aged 3-16.99 years) with similar number of children from Bangladeshi and British Caucasian ethnic origin. Panoramic radiographs were examined and seven mandibular teeth staged according to Demirjian's dental maturity scale [A. Demirjian, Dental development, CD-ROM, Silver Platter Education, University of Montreal, Montreal, 1993-1994; A. Demirjian, H. Goldstein, J.M. Tanner, A new system of dental age assessment, Hum. Biol. 45 (1973) 211-227; A. Demirjian, H. Goldstein, New systems for dental maturity based on seven and four teeth, Ann. Hum. Biol. 3 (1976) 411-421], Nolla [C.M. Nolla, The development of the permanent teeth, J. Dent. Child. 27 (1960) 254-266] and Haavikko [K. Haavikko, The formation and the alveolar and clinical eruption of the permanent teeth. An orthopantomographic study. Proc. Finn. Dent. Soc. 66 (1970) 103-170]. Dental age was calculated for each method, including an adaptation of Demirjian's method with updated scoring [G. Willems, A. Van Olmen, B. Spiessens, C. Carels, Dental age estimation in Belgian children: Demirjian's technique revisited, J. Forensic Sci. 46 (2001) 893-895]. The mean difference (+/-S.D. in years) between dental and real age was calculated for each method and in the case of Haavikko, each tooth type; and tested using t-test. Mean difference was also calculated for the age group 3-13.99 years for Haavikko (mean and individual teeth). Results show that the most accurate method was by Willems [G. Willems, A. Van Olmen, B. Spiessens, C. Carels, Dental age estimation in Belgian children: Demirjian's technique revisited, J. Forensic Sci

  9. Implementation of an agile maintenance mechanic assignment methodology

    NASA Astrophysics Data System (ADS)

    Jimenez, Jesus A.; Quintana, Rolando

    2000-10-01

    The objective of this research was to develop a decision support system (DSS) to study the impact of introducing new equipment into a medical apparel plant from a maintenance organizational structure perspective. This system will enable the company to determine if their capacity is sufficient to meet current maintenance challenges. The DSS contains two database sets that describe equipment and maintenance resource profiles. The equipment profile specifies data such as mean time to failures, mean time to repairs, and minimum mechanic skill level required to fix each machine group. Similarly, maintenance-resource profile reports information about the mechanic staff, such as number and type of certifications received, education level, and experience. The DSS will then use this information to minimize machine downtime by assigning the highest skilled mechanics to machines with higher complexity and product value. A modified version of the simplex method, the transportation problem, was used to perform the optimization. The DSS was built using the Visual Basic for Applications (VBA) language contained in the Microsoft Excel environment. A case study was developed from current existing data. The analysis consisted of forty-two machine groups and six mechanic categories with ten skill levels. Results showed that only 56% of the mechanic workforce was utilized. Thus, the company had available resources for meeting future maintenance requirements.

  10. Development of nondestructive evaluation methods for ceramic coatings.

    SciTech Connect

    Sun, J. G.

    2007-01-01

    Various nondestructive evaluation (NDE) technologies are being developed to advance the knowledge of ceramic coatings for components in the hot gas-path of advanced, low-emission gas-fired turbine engines. The ceramic coating systems being studied by NDE include thermal barrier coatings (TBCs) and environmental barrier coatings (EBCs). TBCs are under development for vanes, blades and combustor liners to allow hotter gas path temperatures and EBCs are under development to reduce environmental damage to high temperature components made of ceramic matrix composites (CMCs). Data provided by NDE methods will be used to: (a) provide data to assess reliability of new coating application processes, (b) identify defective components that could cause unscheduled outages (c) track growth rates of defects during use in engines and (d) allow rational judgement for replace/repair/re-use decisions of components.

  11. User Experience Evaluation Methods in Product Development (UXEM'09)

    NASA Astrophysics Data System (ADS)

    Roto, Virpi; Väänänen-Vainio-Mattila, Kaisa; Law, Effie; Vermeeren, Arnold

    High quality user experience (UX) has become a central competitive factor of product development in mature consumer markets [1]. Although the term UX originated from industry and is a widely used term also in academia, the tools for managing UX in product development are still inadequate. A prerequisite for designing delightful UX in an industrial setting is to understand both the requirements tied to the pragmatic level of functionality and interaction and the requirements pertaining to the hedonic level of personal human needs, which motivate product use [2]. Understanding these requirements helps managers set UX targets for product development. The next phase in a good user-centered design process is to iteratively design and evaluate prototypes [3]. Evaluation is critical for systematically improving UX. In many approaches to UX, evaluation basically needs to be postponed until the product is fully or at least almost fully functional. However, in an industrial setting, it is very expensive to find the UX failures only at this phase of product development. Thus, product development managers and developers have a strong need to conduct UX evaluation as early as possible, well before all the parts affecting the holistic experience are available. Different types of products require evaluation on different granularity and maturity levels of a prototype. For example, due to its multi-user characteristic, a community service or an enterprise resource planning system requires a broader scope of UX evaluation than a microwave oven or a word processor that is meant for a single user at a time. Before systematic UX evaluation can be taken into practice, practical, lightweight UX evaluation methods suitable for different types of products and different phases of product readiness are needed. A considerable amount of UX research is still about the conceptual frameworks and models for user experience [4]. Besides, applying existing usability evaluation methods (UEMs) without

  12. Evaluating a physician leadership development program - a mixed methods approach.

    PubMed

    Throgmorton, Cheryl; Mitchell, Trey; Morley, Tom; Snyder, Marijo

    2016-05-16

    Purpose - With the extent of change in healthcare today, organizations need strong physician leaders. To compensate for the lack of physician leadership education, many organizations are sending physicians to external leadership programs or developing in-house leadership programs targeted specifically to physicians. The purpose of this paper is to outline the evaluation strategy and outcomes of the inaugural year of a Physician Leadership Academy (PLA) developed and implemented at a Michigan-based regional healthcare system. Design/methodology/approach - The authors applied the theoretical framework of Kirkpatrick's four levels of evaluation and used surveys, observations, activity tracking, and interviews to evaluate the program outcomes. The authors applied grounded theory techniques to the interview data. Findings - The program met targeted outcomes across all four levels of evaluation. Interview themes focused on the significance of increasing self-awareness, building relationships, applying new skills, and building confidence. Research limitations/implications - While only one example, this study illustrates the importance of developing the evaluation strategy as part of the program design. Qualitative research methods, often lacking from learning evaluation design, uncover rich themes of impact. The study supports how a PLA program can enhance physician learning, engagement, and relationship building throughout and after the program. Physician leaders' partnership with organization development and learning professionals yield results with impact to individuals, groups, and the organization. Originality/value - Few studies provide an in-depth review of evaluation methods and outcomes of physician leadership development programs. Healthcare organizations seeking to develop similar in-house programs may benefit applying the evaluation strategy outlined in this study. PMID:27119393

  13. The NASA digital VGH program. Exploration of methods and final results. Volume 1: Development of methods

    NASA Technical Reports Server (NTRS)

    Crabill, Norman L.

    1989-01-01

    Two hundred hours of Lockheed L 1011 digital flight data recorder data taken in 1973 were used to develop methods and procedures for obtaining statistical data useful for updating airliner airworthiness design criteria. Five thousand hours of additional data taken in 1978 to 1982 are reported in volumes 2, 3, 4 and 5.

  14. Development of NDE methods for hot gas filters.

    SciTech Connect

    Deemer, C.; Ellingson, W. A.; Koehl, E. R.; Lee, H.; Spohnholtz, T.; Sun, J. G.

    1999-07-21

    Ceramic hot gas candle filters are currently under development for hot gas particulate cleanup in advanced coal-based power systems. The ceramic materials for these filters include nonoxide monolithic, nonoxide-fiber-reinforced composites, and nonoxide reticulated foam. A concern is the lack of reliable data on which to base decisions for reusing or replacing hot gas filters during plant shutdowns. The work in this project is aimed at developing nondestructive evaluation (FIDE) technology to allow detection, and determination of extent, of life-limiting characteristics such as thermal fatigue, oxidation, damage from ash bridging such as localized cracking, damage from local burning, and elongation at elevated temperature. Although in-situ NDE methods are desirable in order to avoid disassembly of the candle filter vessels, the current vessel designs, the presence of filter cakes and possible ash bridging, and the state of NDE technology prevent this. Candle filter producers use a variety of NDE methods to ensure as-produced quality. While impact acoustic resonance offers initial promise for examining new as-produced filters and for detecting damage in some monolithic filters when removed from service, it presents difficulties in data interpretation, it lacks localization capability, and its applicability to composites has yet to be demonstrated. Additional NDE technologies being developed and evaluated in this program and whose applicability to both monolithics and composites has been demonstrated include (a) full-scale thermal imaging for analyzing thermal property variations; (b) fret, high-spatial-resolution X-ray imaging for detecting density variations and dimensional changes; (c) air-coupled ultrasonic methods for determining through-thickness compositional variations; and (d) acoustic emission technology with mechanical loading for detecting localized bulk damage. New and exposed clay-bonded SiC filters and CVI-SiC composite filters have been tested with

  15. Development of an Immunoaffinity Method for Purification of Streptokinase

    PubMed Central

    Karimi, Zohreh; Babashamsi, Mohammad; Asgarani, Ezat; Salimi, Ali

    2012-01-01

    Background Streptokinase is a potent activator of plasminogen to plasmin, the enzyme that can solubilize the fibrin network in blood clots. Streptokinase is currently used in clinical medicine as a thrombolytic agent. It is naturally secreted by β-hemolytic streptococci. Methods To reach an efficient method of purification, an immunoaffinity chromatography method was developed that could purify the streptokinase in a single step with high yield. At the first stage, a CNBr-Activated sepharose 4B-Lysine column was made to purify the human blood plasminogen. The purified plasminogen was utilized to construct a column that could purify the streptokinase. The rabbit was immunized with the purified streptokinase and the anti-streptokinase (IgG) purified on another streptokinase substituted sepharose-4B column. The immunoaffinity column was developed by coupling the purified anti-Streptokinase (IgG) to sepharose 6MB–Protein A. The Escherichia coli (E.coli) BL21 (DE3) pLysS strain was transformed by the recombinant construct (cloned streptokinase gene in pGEX-4T-2 vector) and gene expression was induced by IPTG. The expressed protein was purified by immunoaffinity chromatography in a single step. Results The immunoaffinity column could purify the recombinant fusion GST-SK to homogeneity. The purity of streptokinase was confirmed by SDS-PAGE as a single band of about 71 kD and its biological activity determined in a specific streptokinase assay. The yield of the purification was about 94%. Conclusion This method of streptokinase purification is superior to the previous conventional methods. PMID:23408770

  16. Development of nondestructive evaluation methods for structural ceramics.

    SciTech Connect

    Ellingson, W. A.

    1998-08-19

    During the past year, the focus of our work on nondestructive evaluation (NDE) methods was on the development and application of these methods to technologies such as ceramic matrix composite (CMC) hot-gas filters, CMC high-temperature heat exchangers, and CMC ceramic/ceramic joining. Such technologies are critical to the ''Vision 21 Energy-Plex Fleet'' of modular, high-efficiency, low-emission power systems. Specifically, our NDE work has continued toward faster, higher sensitivity, volumetric X-ray computed tomographic imaging with new amorphous silicon detectors to detect and measure axial and radial density variations in hot-gas filters and heat exchangers; explored the potential use of high-speed focal-plane-array infrared imaging technology to detect delaminations and variations in the thermal properties of SiC/SiC heat exchangers; and explored various NDE methods to characterize CMC joints in cooperation with various industrial partners. Work this year also addressed support of Southern Companies Services Inc., Power Systems Development Facility, where NDE is needed to assess the condition of hot-gas candle filters. This paper presents the results of these efforts.

  17. Development of nondestructive evaluation methods for ceramic coatings.

    SciTech Connect

    Ellingson, W. A.; Deemer, C.; Sun, J. G.; Erdman, S.; Muliere, D.; Wheeler, B.

    2002-04-29

    Various nondestructive evaluation (NDE) technologies are being developed to study the use of ceramic coatings on components in the hot-gas path of advanced low-emission gas-fired turbines. The types of ceramic coatings include thermal barrier coatings (TBCs) and environmental barrier coatings (EBCs). TBCs are under development for vanes, blades, and combustor liners to allow hotter gas-path temperatures, and EBCs are under development to reduce environmental damage to high-temperature components made of ceramic matrix composites. The NDE methods will be used to (a) provide data to assess the reliability of new coating application processes, (b) identify defective components that could cause unscheduled outages, (c) track growth rates of defects during component use in engines, and (d) allow rational judgment for replace/repair/re-use decisions regarding components. Advances in TBC application, both electron beam-physical vapor deposition (EB-PVD) and air plasma spraying (APS), are allowing higher temperatures in the hot-gas path. However, as TBCs become ''prime reliant,'' their condition at scheduled or unscheduled outages must be known. NDE methods are under development to assess the condition of the TBC for pre-spall conditions. EB-PVD test samples with up to 70 thermal cycles have been studied by a newly developed method involving polarized laser back-scatter NDE. Results suggest a correlation between the NDE laser data and the TBC/bond-coat topography. This finding is important because several theories directed toward understanding the pre-spall condition suggest that the topography in the thermally grown oxide layer changes significantly as a function of the number of thermal cycles. Tests have also been conducted with this NDE method on APS TBCs. Results suggest that the pre-spall condition is detected for these coatings. One-sided, high-speed thermal imaging also has shown promise for NDE of APS coatings. Testing of SiC/SiC composites for combustor liners

  18. Development of computational methods for heavy lift launch vehicles

    NASA Technical Reports Server (NTRS)

    Yoon, Seokkwan; Ryan, James S.

    1993-01-01

    The research effort has been focused on the development of an advanced flow solver for complex viscous turbulent flows with shock waves. The three-dimensional Euler and full/thin-layer Reynolds-averaged Navier-Stokes equations for compressible flows are solved on structured hexahedral grids. The Baldwin-Lomax algebraic turbulence model is used for closure. The space discretization is based on a cell-centered finite-volume method augmented by a variety of numerical dissipation models with optional total variation diminishing limiters. The governing equations are integrated in time by an implicit method based on lower-upper factorization and symmetric Gauss-Seidel relaxation. The algorithm is vectorized on diagonal planes of sweep using two-dimensional indices in three dimensions. A new computer program named CENS3D has been developed for viscous turbulent flows with discontinuities. Details of the code are described in Appendix A and Appendix B. With the developments of the numerical algorithm and dissipation model, the simulation of three-dimensional viscous compressible flows has become more efficient and accurate. The results of the research are expected to yield a direct impact on the design process of future liquid fueled launch systems.

  19. Recent developments in methods for analysis of perfluorinated persistent pollutants.

    PubMed

    Trojanowicz, Marek; Koc, Mariusz

    2013-01-01

    Perfluoroalkyl substances (PFASs) are proliferated into the environment on a global scale and present in the organisms of animals and humans even in remote locations. Persistent organic pollutants of that kind therefore have stimulated substantial improvement in analytical methods. The aim of this review is to present recent achievements in PFASs determination in various matrices with different methods and its comparison to measurements of Total Organic Fluorine (TOF). Analytical methods used for PFASs determinations are dominated by chromatography, mostly in combination with mass spectrometric detection. However, HPLC may be also hyphenated with conductivity or fluorimetric detection, and gas chromatography may be combined with flame ionization or electron capture detection. The presence of a large number of PFASs species in environmental and biological samples necessitates parallel attempts to develop a total PFASs index that reflects the total content of PFASs in various matrices. Increasing attention is currently paid to the determination of branched isomers of PFASs, and their determination in food. FigureThe aim of this review is to present recent achievements in perfluoroalkyl substances (PFASs) determination in various matrices with different methods and its comparison to measurements of Total Organic Fluorine (TOF). Increasing attention is currently paid to the determination of branched isomers of PFASs, and their determination in food. PMID:23913984

  20. Developing a Method to Mask Trees in Commercial Multispectral Imagery

    NASA Astrophysics Data System (ADS)

    Becker, S. J.; Daughtry, C. S. T.; Jain, D.; Karlekar, S. S.

    2015-12-01

    The US Army has an increasing focus on using automated remote sensing techniques with commercial multispectral imagery (MSI) to map urban and peri-urban agricultural and vegetative features; however, similar spectral profiles between trees (i.e., forest canopy) and other vegetation result in confusion between these cover classes. Established vegetation indices, like the Normalized Difference Vegetation Index (NDVI), are typically not effective in reliably differentiating between trees and other vegetation. Previous research in tree mapping has included integration of hyperspectral imagery (HSI) and LiDAR for tree detection and species identification, as well as the use of MSI to distinguish tree crowns from non-vegetated features. This project developed a straightforward method to model and also mask out trees from eight-band WorldView-2 (1.85 meter x 1.85 meter resolution at nadir) satellite imagery at the Beltsville Agricultural Research Center in Beltsville, MD spanning 2012 - 2015. The study site included tree cover, a range of agricultural and vegetative cover types, and urban features. The modeling method exploits the product of the red and red edge bands and defines accurate thresholds between trees and other land covers. Results show this method outperforms established vegetation indices including the NDVI, Soil Adjusted Vegetation Index, Normalized Difference Water Index, Simple Ratio, and Normalized Difference Red Edge Index in correctly masking trees while preserving the other information in the imagery. This method is useful when HSI and LiDAR collection are not possible or when using archived MSI.