Science.gov

Sample records for aging gateway building

  1. Optical gateway for intelligent buildings: a new open-up window to the optical fibre sensors market?

    NASA Astrophysics Data System (ADS)

    Fernandez-Valdivielso, Carlos; Matias, Ignacio R.; Arregui, Francisco J.; Bariain, Candido; Lopez-Amo, Manuel

    2004-06-01

    This paper presents the first optical fiber sensor gateway for integrating these special measurement devices in Home Automation Systems, concretely in those buildings that use the KNX European Intelligent Buildings Standard.

  2. 77 FR 29677 - National Institute on Aging Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    ... review and evaluate grant applications. Place: National Institute on Aging, Gateway Building, 7201..., Ph.D., Scientific Review Branch, National Institute on Aging, Gateway Building, Suite 2C212, MSC... applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite...

  3. Gateway to the Future

    ERIC Educational Resources Information Center

    DiJulio, Betsy

    2012-01-01

    "Gateway to the Future" pairs a painting of a gateway constructed from children's building blocks with an ink drawing of a personal symbol on a collaged background. The main objective of this lesson is to create a metaphoric artwork about moving from the present through a symbolic portal to the future. So, space--foreground, middle ground, and…

  4. Gateways Revitalization Strategy

    EPA Pesticide Factsheets

    Lancaster County, PA, created the Gateway plan to reconnect various areas of the community, revitalize the economic base, improve and build on infrastructure and public/private partnerships, and retain current residents.

  5. GEOCAB Portal: A gateway for discovering and accessing capacity building resources in Earth Observation

    NASA Astrophysics Data System (ADS)

    Desconnets, Jean-Christophe; Giuliani, Gregory; Guigoz, Yaniss; Lacroix, Pierre; Mlisa, Andiswa; Noort, Mark; Ray, Nicolas; Searby, Nancy D.

    2017-02-01

    The discovery of and access to capacity building resources are often essential to conduct environmental projects based on Earth Observation (EO) resources, whether they are Earth Observation products, methodological tools, techniques, organizations that impart training in these techniques or even projects that have shown practical achievements. Recognizing this opportunity and need, the European Commission through two FP7 projects jointly with the Group on Earth Observations (GEO) teamed up with the Committee on Earth observation Satellites (CEOS). The Global Earth Observation CApacity Building (GEOCAB) portal aims at compiling all current capacity building efforts on the use of EO data for societal benefits into an easily updateable and user-friendly portal. GEOCAB offers a faceted search to improve user discovery experience with a fully interactive world map with all inventoried projects and activities. This paper focuses on the conceptual framework used to implement the underlying platform. An ISO19115 metadata model associated with a terminological repository are the core elements that provide a semantic search application and an interoperable discovery service. The organization and the contribution of different user communities to ensure the management and the update of the content of GEOCAB are addressed.

  6. TOAD Gateway

    NASA Technical Reports Server (NTRS)

    Bingel, Bradford D.

    1994-01-01

    TOAD Gateway is interactive software tool for converting data files to and from variety of file formats. Currently reads and writes following file formats: TOAD; Standard Interface File (SIF); Program to Optimize Simulated Trajectories (POST) input; Comma Separated Value and Tab Separated Value, common in PC and Macintosh spreadsheet and database packages; and general free format. Additional modules for accommodating other formats easily developed and installed. Companion program, TOAD Editor (LAR-14423), manipulates contents of TOAD files and extracts selected subsets of data. TOAD Gateway written in FORTRAN 77.

  7. 77 FR 40368 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel Age, Gene/Environment Susceptibility... evaluate contract proposals. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin...

  8. 77 FR 9670 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-17

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's Prevention. Date: March 1, 2012...., Scientific Review Officer, National Institute on Aging, Scientific Review Branch, Gateway Building...

  9. 77 FR 50704 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Drug Development for Alzheimer's Disease... applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite...

  10. 75 FR 4829 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-29

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Development and Maintenance of a... contract proposals. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Ave, Suite...

  11. 77 FR 2737 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Development and Maintenance of a... and evaluate contract proposals. Place: National Institute on Aging, Gateway Building, 7201...

  12. 75 FR 26969 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-13

    ... . Name of Committee: National Institute on Aging Special Emphasis Panel; Protein Quality Control. Date... patentable material, and personal information concerning individuals associated with the grant applications... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892 (Telephone...

  13. Science gateways for semantic-web-based life science applications.

    PubMed

    Ardizzone, Valeria; Bruno, Riccardo; Calanducci, Antonio; Carrubba, Carla; Fargetta, Marco; Ingrà, Elisa; Inserra, Giuseppina; La Rocca, Giuseppe; Monforte, Salvatore; Pistagna, Fabrizio; Ricceri, Rita; Rotondo, Riccardo; Scardaci, Diego; Barbera, Roberto

    2012-01-01

    In this paper we present the architecture of a framework for building Science Gateways supporting official standards both for user authentication and authorization and for middleware-independent job and data management. Two use cases of the customization of the Science Gateway framework for Semantic-Web-based life science applications are also described.

  14. Building Gateway Tools for Informed Decision Making: The Drought Risk Atlas and U.S. Drought Monitor

    NASA Astrophysics Data System (ADS)

    Svoboda, M.; Fuchs, B.; Poulsen, C.; Nothwehr, J.; Owen, S.

    2014-12-01

    The National Drought Mitigation Center (NDMC) (http://drought.unl.edu) has been working with the National Integrated Drought Information System (NIDIS) (http://drought.gov;) and other partners with a goal of developing tools to enhance drought risk management activities in the U.S. and around the world. The NDMC is a national center founded in 1995 and located at the University of Nebraska-Lincoln. The NDMC conducts basic and applied research, provides a variety of services and produces decision support applications. In addition, the NDMC is involved heavily in education, outreach and planning activities and maintains a number of operational drought-related tools and products including the U.S. Drought Monitor (USDM), Drought Impact Reporter (DIR), Vegetation Drought Response Index (VegDRI) and the Drought Risk Atlas (DRA). The NDMC's recently launched Drought Risk Atlas (DRA) (http://droughtatlas.unl.edu) and the continually evolving U.S. Drought Monitor (http://droughtmonitor.unl.edu;) will be the focus of this presentation. The DRA was launched in 2014 in order to help better answer the common questions of "How does this drought compare to the Dust Bowl years or some other regional drought of record?", or "How often do we see a drought as severe as this?", and "Are we seeing trends in drought frequency?". Access to new digital data sources, geospatial tools and analyses, and dissemination through a web-based interface has allowed us to triple the original National Drought Atlas station sample size and roughly double the period of record in standing up the new DRA. Building off of feedback from the user community, the SPI, SPEI, PDSI, self-calibrated PDSI, Deciles and other climatology (to also include hydrology) products are included. It is anticipated that this tool will heighten awareness and enhance decision support activities with regards to drought risk for policy makers, resource managers, producers, planners, media and the public. Examples of the DRA

  15. Building a Gateway for the CD-ROM Network: A Step toward the Virtual Library with the Virtual Microsystems V-Server.

    ERIC Educational Resources Information Center

    Sylvia, Margaret

    1993-01-01

    Describes one college library's experience with a gateway for dial-in access to its CD-ROM network to increase access to automated index searching for students off-campus. Hardware and software choices are discussed in terms of access, reliability, affordability, and ease of use. Installation problems are discussed, and an appendix lists product…

  16. Building Peer Relationships in School Age Care. Beginnings Workshop.

    ERIC Educational Resources Information Center

    Teachy, Cindy L.; And Others

    1994-01-01

    This workshop section includes four essays: (1) "Building Lifelong Relationships: School Age Programs at Work" (Cindy L. Teachey); (2) "Building Friendships in School Age Programs" (Joan M. Bergstrom); (3) "On the Rocky Road to Friendship: Emerging Peer Relationships" (Kay Albrecht); (4) "Helping Teachers Understand Their Role in Supporting Peer…

  17. Symposium on GPO Access and the Model Gateway Experience.

    ERIC Educational Resources Information Center

    Sulzer, Jack, Ed.; And Others

    1995-01-01

    Five articles describe the involvement of the Government Printing Office (GPO) and four depository libraries in the initial GPO Access Gateway Library Program. Technical issues and innovations are discussed, and the challenges of building such a program are outlined. (AEF)

  18. Remote Sensing Information Gateway

    EPA Pesticide Factsheets

    Remote Sensing Information Gateway, a tool that allows scientists, researchers and decision makers to access a variety of multi-terabyte, environmental datasets and to subset the data and obtain only needed variables, greatly improving the download time.

  19. Aging in Taiwan: Building a Society for Active Aging and Aging in Place.

    PubMed

    Lin, Yi-Yin; Huang, Chin-Shan

    2016-04-01

    Taiwan's accelerated rate of aging is more than twice that of European countries and United States. Although demographic aging was not a major concern in Taiwan until 1993, when it became an aging society, aging issues now have become an imperative topic both in policy and in practice in the country. As this article demonstrates, in response to the challenge of the rapidly growing older population and the inspiration of cultural values of filial obligation and respect to elders, the concepts of active aging and aging in place are leading the policies and practices of gerontology to meet the diverse needs of the aging population in Taiwan. However, challenges remain, including the question of how to promote systematic endeavors, both in policies or research on aging, and how to encourage greater involvement of nongovernment organizations in the aging issue. In addition, some emerging issues about aging are addressed in this article including inadequate resources for older rural adults, building an age-friendly environment, and the increasing number of people with dementia.

  20. 76 FR 21386 - National Institute on Aging

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-15

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Organelle Lifespan Mechanism II. Date: June... Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892...

  1. 76 FR 65203 - National Institute on Aging

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-20

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging ACTION: Notice of Closed... of Committee: National Institute on Aging Special Emphasis Panel; Mechanisms of Osteoporosis II. Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  2. Intelligent Campus Buildings for the Information Age.

    ERIC Educational Resources Information Center

    Caloz, Jack

    2000-01-01

    Discusses three "information age" trends that have colleges and universities re-examining their campus infrastructure flexibility to support these wireless communication needs. Trends examined are information technology; increased demand for flexible, technology- focused teaching spaces; and increased systems' interconnectivity. (GR)

  3. Select aging biomarkers based on telomere length and chronological age to build a biological age equation.

    PubMed

    Zhang, Wei-Guang; Zhu, Shu-Ying; Bai, Xiao-Juan; Zhao, De-Long; Jian, Shi-Min; Li, Juan; Li, Zuo-Xiang; Fu, Bo; Cai, Guang-Yan; Sun, Xue-Feng; Chen, Xiang-Mei

    2014-06-01

    The purpose of this study is to build a biological age (BA) equation combining telomere length with chronological age (CA) and associated aging biomarkers. In total, 139 healthy volunteers were recruited from a Chinese Han cohort in Beijing. A genetic index, renal function indices, cardiovascular function indices, brain function indices, and oxidative stress and inflammation indices (C-reactive protein [CRP]) were measured and analyzed. A BA equation was proposed based on selected parameters, with terminal telomere restriction fragment (TRF) and CA as the two principal components. The selected aging markers included mitral annulus peak E anterior wall (MVEA), intima-media thickness (IMT), cystatin C (CYSC), D-dimer (DD), and digital symbol test (DST). The BA equation was: BA = −2.281TRF + 26.321CYSC + 0.025DD − 104.419MVEA + 34.863IMT − 0.265DST + 0.305CA + 26.346. To conclude, telomere length and CA as double benchmarks may be a new method to build a BA.

  4. BSV Gateway Description

    SciTech Connect

    Deshpande, Alina

    2015-03-26

    Los Alamos National Laboratory (LANL) is part of that worldwide team and has been developing state of the art information systems to aid the global health community. For instance, in 2014 LANL announced the release of the LANL Biosurveillance (BSV) Gateway. The site provides information about ongoing biosurveillance research projects and capabilities at LANL, and provides access to a host of LANL-developed biosurveillance tools and resources. We are seeking feedback on this gateway and would like to ask interested folk to offer comments and suggestions after they have perused the BSV website.

  5. Remote Asynchronous Message Service Gateway

    NASA Technical Reports Server (NTRS)

    Wang, Shin-Ywan; Burleigh, Scott C.

    2011-01-01

    The Remote Asynchronous Message Service (RAMS) gateway is a special-purpose AMS application node that enables exchange of AMS messages between nodes residing in different AMS "continua," notionally in different geographical locations. JPL s implementation of RAMS gateway functionality is integrated with the ION (Interplanetary Overlay Network) implementation of the DTN (Delay-Tolerant Networking) bundle protocol, and with JPL s implementation of AMS itself. RAMS protocol data units are encapsulated in ION bundles and are forwarded to the neighboring RAMS gateways identified in the source gateway s AMS management information base. Each RAMS gateway has interfaces in two communication environments: the AMS message space it serves, and the RAMS network - the grid or tree of mutually aware RAMS gateways - that enables AMS messages produced in one message space to be forwarded to other message spaces of the same venture. Each gateway opens persistent, private RAMS network communication channels to the RAMS gateways of other message spaces for the same venture, in other continua. The interconnected RAMS gateways use these communication channels to forward message petition assertions and cancellations among themselves. Each RAMS gateway subscribes locally to all subjects that are of interest in any of the linked message spaces. On receiving its copy of a message on any of these subjects, the RAMS gateway node uses the RAMS network to forward the message to every other RAMS gateway whose message space contains at least one node that has subscribed to messages on that subject. On receiving a message via the RAMS network from some other RAMS gateway, the RAMS gateway node forwards the message to all subscribers in its own message space.

  6. Examining Strategies to Build and Sustain Healthy Aging Programming Collaboratives

    ERIC Educational Resources Information Center

    Altpeter, Mary; Schneider, Ellen Caylor; Whitelaw, Nancy

    2014-01-01

    Background: Community collaboratives provide a means to build local capacity, reduce service fragmentation and duplication, maximize efficiency, and create synergies for "systems change". But what are the collaborative practices that aging services providers and other stakeholders employ for "system change" and…

  7. Space Station Freedom Gateway to the Future

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The first inhabited outpost on the frontier of space will be a place to live, work, and discover. Experiments conducted on Freedom will advance scientific knowledge about our world, our environment, and ourselves. We will learn how to adapt to the space environment and to build and operate new spacecraft with destinations far beyond Earth, continuing the tradition of exploration that began with a journey to the Moon. What we learn from living and working on Freedom will strengthen our expertise in science and engineering, promote national research and development initiatives and inspire another generation of Americans to push forward and onward. On the eve of the 21st century, Space Station Freedom will be our gateway to the future. This material covers gateways to space, research, discovery, utilization, benefits, and NASA.

  8. 78 FR 20669 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-05

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Management of the Primate Aging Database Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  9. 77 FR 34394 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Healthy Aging and the Life Course. Date: June...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  10. 78 FR 55752 - National Institute On Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-11

    ... HUMAN SERVICES National Institutes of Health National Institute On Aging; Notice of Closed Meeting... Committee: National Institute on Aging Initial Review Group, Behavior and Social Science of Aging Review...: Rebecca J. Ferrell, Ph.D., Scientific Review Officer, National Institute on Aging, Gateway Building,...

  11. 75 FR 39698 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-12

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel, Network Infrastructure for Aging Research...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  12. 77 FR 63843 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-17

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Aging and Sleep. Date: November 8, 2012. Time... on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892,...

  13. 76 FR 32977 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-07

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Aging and Economics. Date: June 24, 2011... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892 (Telephone...

  14. 77 FR 40370 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Aging and Innovation. Date: July 11, 2012... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, (Telephone...

  15. 76 FR 57064 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Initial Review Group, Clinical Aging Review Committee. Date: October... Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892. Contact...

  16. 77 FR 14026 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-08

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Reprogramming, Aging and Alzheimer's Disease... Lewis, Ph.D., Scientific Review Branch, National Institute on Aging, Gateway Building, Suite 2C212,...

  17. 76 FR 3148 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-19

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Initial Review Group; Biological Aging Review Committee. Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  18. 75 FR 79386 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Hormone Therapy and Cognitive Aging. Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  19. 75 FR 18513 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-12

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Aging Program Project Review. Date: May 5... Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892...

  20. 75 FR 63497 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Genetic Determinants of Healthy Aging. Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  1. 75 FR 67381 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-02

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel HIV, HAART and AGING. Date: November 23, 2010... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, (Telephone...

  2. 77 FR 11563 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-27

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Systems Biology of Aged in Yeast. Date: March... Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892,...

  3. 77 FR 58854 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-24

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel Cognitive Aging. Date: November 7, 2012 Time... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892 Contact...

  4. NASA gateway requirements analysis

    NASA Technical Reports Server (NTRS)

    Duncan, Denise R.; Doby, John S.; Shockley, Cynthia W.

    1991-01-01

    NASA devotes approximately 40 percent of its budget to R&D. Twelve NASA Research Centers and their contractors conduct this R&D, which ranges across many disciplines and is fueled by information about previous endeavors. Locating the right information is crucial. While NASA researchers use peer contacts as their primary source of scientific and technical information (STI), on-line bibliographic data bases - both Government-owned and commercial - are also frequently consulted. Once identified, the STI must be delivered in a usable format. This report assesses the appropriateness of developing an intelligent gateway interface for the NASA R&D community as a means of obtaining improved access to relevant STI resources outside of NASA's Remote Console (RECON) on-line bibliographic database. A study was conducted to determine (1) the information requirements of the R&D community, (2) the information sources to meet those requirements, and (3) ways of facilitating access to those information sources. Findings indicate that NASA researchers need more comprehensive STI coverage of disciplines not now represented in the RECON database. This augmented subject coverage should preferably be provided by both domestic and foreign STI sources. It was also found that NASA researchers frequently request rapid delivery of STI, in its original format. Finally, it was found that researchers need a better system for alerting them to recent developments in their areas of interest. A gateway that provides access to domestic and international information sources can also solve several shortcomings in the present STI delivery system. NASA should further test the practicality of a gateway as a mechanism for improved STI access.

  5. Local geology controlled the feasibility of vitrifying Iron Age buildings

    PubMed Central

    Wadsworth, Fabian B.; Heap, Michael J.; Damby, David E.; Hess, Kai-Uwe; Najorka, Jens; Vasseur, Jérémie; Fahrner, Dominik; Dingwell, Donald B.

    2017-01-01

    During European prehistory, hilltop enclosures made from polydisperse particle-and-block stone walling were exposed to temperatures sufficient to partially melt the constituent stonework, leading to the preservation of glassy walls called ‘vitrified forts’. During vitrification, the granular wall rocks partially melt, sinter viscously and densify, reducing inter-particle porosity. This process is strongly dependent on the solidus temperature, the particle sizes, the temperature-dependence of the viscosity of the evolving liquid phase, as well as the distribution and longevity of heat. Examination of the sintering behaviour of 45 European examples reveals that it is the raw building material that governs the vitrification efficiency. As Iron Age forts were commonly constructed from local stone, we conclude that local geology directly influenced the degree to which buildings were vitrified in the Iron Age. Additionally, we find that vitrification is accompanied by a bulk material strengthening of the aggregates of small sizes, and a partial weakening of larger blocks. We discuss these findings in the context of the debate surrounding the motive of the wall-builders. We conclude that if wall stability by bulk strengthening was the desired effect, then vitrification represents an Iron Age technology that failed to be effective in regions of refractory local geology. PMID:28079121

  6. Local geology controlled the feasibility of vitrifying Iron Age buildings.

    PubMed

    Wadsworth, Fabian B; Heap, Michael J; Damby, David E; Hess, Kai-Uwe; Najorka, Jens; Vasseur, Jérémie; Fahrner, Dominik; Dingwell, Donald B

    2017-01-12

    During European prehistory, hilltop enclosures made from polydisperse particle-and-block stone walling were exposed to temperatures sufficient to partially melt the constituent stonework, leading to the preservation of glassy walls called 'vitrified forts'. During vitrification, the granular wall rocks partially melt, sinter viscously and densify, reducing inter-particle porosity. This process is strongly dependent on the solidus temperature, the particle sizes, the temperature-dependence of the viscosity of the evolving liquid phase, as well as the distribution and longevity of heat. Examination of the sintering behaviour of 45 European examples reveals that it is the raw building material that governs the vitrification efficiency. As Iron Age forts were commonly constructed from local stone, we conclude that local geology directly influenced the degree to which buildings were vitrified in the Iron Age. Additionally, we find that vitrification is accompanied by a bulk material strengthening of the aggregates of small sizes, and a partial weakening of larger blocks. We discuss these findings in the context of the debate surrounding the motive of the wall-builders. We conclude that if wall stability by bulk strengthening was the desired effect, then vitrification represents an Iron Age technology that failed to be effective in regions of refractory local geology.

  7. Local geology controlled the feasibility of vitrifying Iron Age buildings

    USGS Publications Warehouse

    Fabian B Wadsworth,; Michael J Heap,; Damby, David; Kai-Uwe Hess,; Jens Najorka,; Jérémie Vasseur,; Dominik Fahrner,; Donald B Dingwell,

    2017-01-01

    During European prehistory, hilltop enclosures made from polydisperse particle-and-block stone walling were exposed to temperatures sufficient to partially melt the constituent stonework, leading to the preservation of glassy walls called ‘vitrified forts’. During vitrification, the granular wall rocks partially melt, sinter viscously and densify, reducing inter-particle porosity. This process is strongly dependent on the solidus temperature, the particle sizes, the temperature-dependence of the viscosity of the evolving liquid phase, as well as the distribution and longevity of heat. Examination of the sintering behaviour of 45 European examples reveals that it is the raw building material that governs the vitrification efficiency. As Iron Age forts were commonly constructed from local stone, we conclude that local geology directly influenced the degree to which buildings were vitrified in the Iron Age. Additionally, we find that vitrification is accompanied by a bulk material strengthening of the aggregates of small sizes, and a partial weakening of larger blocks. We discuss these findings in the context of the debate surrounding the motive of the wall-builders. We conclude that if wall stability by bulk strengthening was the desired effect, then vitrification represents an Iron Age technology that failed to be effective in regions of refractory local geology.

  8. 75 FR 11188 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel, Nursing Home Research. Date: May 7, 2010... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892. (Telephone...

  9. 78 FR 32408 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-30

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel Senile Dementia. Date: June 28, 2013. Time: 1... Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda, MD 20892, (Telephone...

  10. 78 FR 9403 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-08

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; CALERIE Dataset. Date: March 7, 2013. Time: 1... Aging, Gateway Building, Room 2C212, 7201 Wisconsin Avenue, Bethesda, MD 20892, (Telephone...

  11. 75 FR 26268 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel, ARRA--Behavioral Economics C.E.R.--Clinical.... Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C218, Bethesda,...

  12. 76 FR 17929 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-31

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Drug Development for Alzheimer's Disease...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  13. 75 FR 3476 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Clinical Services. Date: January 29, 2010... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892. (Telephone...

  14. 77 FR 5030 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel Testosterone Studies. Date: February 16, 2012... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, (Telephone...

  15. 75 FR 56116 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Alzheimer's Disease Genetics. Date: October 4... Officer, National Institute on Aging, Scientific Review Branch, Gateway Building 2c-212, 7201...

  16. 78 FR 4423 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Worm Intervention Study. Date: February 20... Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda, MD 20892,...

  17. 78 FR 51196 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-20

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Juvenile Protective Factors I. Date...: National Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda, MD...

  18. 76 FR 42719 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-19

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, The NIA Health and Retirement Study. Date.... Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda,...

  19. 76 FR 35901 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ... Institute on Aging; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee... clearly unwarranted invasion of personal privacy. Name of Committee: National Institute on Aging Special... evaluate grant applications. Place: National Institute of Aging, Gateway Building, 7201 Wisconsin...

  20. 75 FR 39549 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-09

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; ARRA--MIND MRI. Date: July 26, 2010. Time: 1... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212. Bethesda, MD 20892. (Telephone...

  1. 76 FR 57064 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, AD Genetics Warehouse. Date: October 7, 2011..., Scientific Review Officer, National Institute on Aging, Scientific Review Branch, Gateway Building...

  2. 77 FR 1941 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-12

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; GEMSSTAR. Date: January 27, 2012. Time: 8 a.m...., Scientific Review Officer, National Institute on Aging, Gateway Building, Rm. 2C212, 7201 Wisconsin...

  3. 75 FR 11188 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Beeson Meeting. Date: April 28-29, 2010. Time..., Scientific Review Officer, National Institute on Aging, Scientific Review Branch, Gateway Building...

  4. 77 FR 24728 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Health and Well-Being Across Time. Date: May...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  5. 78 FR 36200 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-17

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Longitudinal Study Contract. Date: June 26... Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20814,...

  6. 77 FR 65005 - National Institute on Aging Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-24

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Juvenile Protective Factors. Date: December 4... Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892. Contact...

  7. 75 FR 25273 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel, Basis of Myocardial Injury in the Elderly...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  8. 77 FR 56855 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Skeletal Muscle. ] Date: October 23, 2012... Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892...

  9. 77 FR 21790 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Loan Repayment 2012. Date: May 2, 2012. Time... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892. Contact Person:...

  10. 77 FR 34396 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Changing Long Term Care in America. Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  11. 76 FR 28794 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-18

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Longevity Consortium. Date: June 9, 2011... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, (Telephone...

  12. 77 FR 21790 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Pathology of Alzheimer's Disease. Date: May 7... Institute on Aging, Gateway Building 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892,...

  13. 76 FR 575 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-05

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; ADCC Meeting. Date: February 24-25, 2011... Review Officer, Scientific Review Branch, National Institute on Aging, Gateway Building, Suite 2C212,...

  14. 76 FR 82313 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-30

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel Beeson Review 2012/05. Date: February 24, 2012... Parsadanian, Ph.D., Scientific Review Officer, National Institute on Aging, Gateway Building 2c/212,...

  15. The healthy aging research network: resources for building capacity for public health and aging practice.

    PubMed

    Wilcox, Sara; Altpeter, Mary; Anderson, Lynda A; Belza, Basia; Bryant, Lucinda; Jones, Dina L; Leith, Katherine H; Phelan, Elizabeth A; Satariano, William A

    2013-01-01

    There is an urgent need to translate science into practice and help enhance the capacity of professionals to deliver evidence-based programming. We describe contributions of the Healthy Aging Research Network in building professional capacity through online modules, issue briefs, monographs, and tools focused on health promotion practice, physical activity, mental health, and environment and policy. We also describe practice partnerships and research activities that helped inform product development and ways these products have been incorporated into real-world practice to illustrate possibilities for future applications. Our work aims to bridge the research-to-practice gap to meet the demands of an aging population.

  16. Gateways to clinical trials.

    PubMed

    Bayés, M; Rabasseda, X; Prous, J R

    2007-01-01

    Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issues focuses on the following selection of drugs: 4'-Thio-ara-C, 5-methyltetrahydrofolate; ABT-089, AD-237, AF-37702, alvocidib hydrochloride, apricitabine, armodafinil, atrasentan, AVE-5883, avian influenza vaccine, azimilide hydrochloride; Banoxantrone, BIBF-1120; CD34+ cells, certolizumab pegol, CHIR-258, cilansetron, CoFactor, CX-3543, cystemustine; D-003, dexloxiglumide, DMXB-anabaseine; Ecogramostim, elcometrine, elcometrine/ethinylestradiol, etravirine; Fenretinide, fingolimod hydrochloride, fospropofol disodium; Gaboxadol, gestodene, glutamine; Human insulin, hyaluronic acid; Incyclinide, indacaterol, ispronicline, istradefylline; Labradimil, lamifiban, lapatinib, L-arginine hydrochloride, liposomal cisplatin, liposome encapsulated paclitaxel, LY-517717; Manidipine hydrochloride/delapril hydrochloride, maraviroc, MBP(82-98), MD-0727, MDX-214, melanotan I, MMR vaccine; Nacystelyn, nalfurafine hydrochloride, nibentan, nilotinib, NK-105; OBI-1, oblimersen sodium, olmesartan medoxomil, olmesartan medoxomil/hydrochlorothiazide, oregovomab; Pexelizumab, PG-116800, PG-CPT, PHA-794428, prasugrel; RC-3095, rDNA insulin, RFB4(dsFv)-PE38, rhEndostatin, rhenium Re-186 etidronate, rhGM-CSF, roflumilast, romidepsin; Sarcosine, SGLU1, SGN-40, succinobucol; TAU, teduglutide, telatinib, tesofensine, tipifarnib, tirapazamine, TKA-731, tolvaptan, trabectedin; Vaccimel, vatalanib succinate, velafermin, vildagliptin, vinflunine; XP-19986; YM-155.

  17. Gateways to clinical trials.

    PubMed

    Bayes, M; Rabasseda, X; Prous, J R

    2002-01-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses, which has been retrieved from the Clinical Studies knowledge area of Prous Science Integrity, the world's first drug discovery and development portal, providing information on study design, treatments, conclusions and references. This issue focuses on the following selection of drugs: Abacavir sulfate; abciximab; abetimus sodium; adalimumab; aldesleukin; almotriptan; alteplase; amisulpride; amitriptyline hydrochloride; amoxicillin trihydrate; atenolol; atorvastatin calcium; atrasentan; Beclometasone dipropionate; bosentan; Captopril; ceftriaxone sodium; cerivastatin sodium; cetirizine hydrochloride; cisplatin; citalopram hydrobromide; Dalteparin sodium; darusentan; desirudin; digoxin; Efalizumab; enoxaparin sodium; ertapenem sodium; esomeprazole magnesium; estradiol; ezetimibe; Famotidine; farglitazar; fluorouracil; fluticasone propionate; fosamprenavir sodium; Glibenclamide; glucosamine sulfate; Heparin sodium; HSPPC-96; hydrochlorothiazide; Imatinib mesilate; implitapide; Lamivudine; lansoprazole; lisinopril; losartan potassium; l-Propionylcarnitine; Melagatran; metformin hydrochloride; methotrexate; methylsulfinylwarfarin; Nateglinide; norethisterone; Olmesartan medoxomil; omalizumab; omapatrilat; omeprazole; oseltamivir phosphate; oxatomide; Pantoprazole; piperacillin sodium; pravastatin sodium; Quetiapine hydrochloride; Rabeprazole sodium; raloxifene hydrochloride; ramosetron hydrochloride; ranolazine; rasburicase; reboxetine mesilate; recombinant somatropin; repaglinide; reteplase; rosiglitazone; rosiglitazone maleate; rosuvastatin calcium; Sertraline; simvastatin; sumatriptan succinate; Tazobactam sodium; tenecteplase; tibolone; tinidazole; tolterodine tartrate; troglitazone; Uniprost; Warfarin sodium; Ximelagatran.

  18. Gateways to clinical trials.

    PubMed

    Bayes, M; Rabasseda, X; Prous, J R

    2002-05-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables can be retrieved from the Clinical Studies knowledge area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: Abacavir sulfate, abarelix, abciximab, acarbose, alefacept, alteplase, amisulpride, amoxicillin trihydrate, apomorphine hydrochloride, aprepitant, argatroban monohydrate, aspirin, atenolol; Betamethasone dipropionate, betamethasone valerate, bicalutamide, bleomycin sulfate; Calcium carbonate, candesartan cilexetil, celecoxib, cetirizine hydrochloride, cisplatin, clarithromycin, clavulanate potassium, clomethiazole edisilate, clopidogrel hydrogensulfate, cyclophosphamide, chorionic gonadotropin (human); Dalteparin sodium, desloratadine, dexamethasone, doxorubicin, DPC-083; Efalizumab, efavirenz, enoxaparin sodium, eprosartan mesilate, etanercept, etoposide, ezetimibe; Faropenem daloxate, fenofibrate, fluocinolone acetonide, flutamide, fluvastatin sodium, follitropin beta, fondaparinux sodium; Gabapentin, glibenclamide, goserelin, granisetron hydrochloride; Haloperidol, hydrochlorothiazide; Imiquimod, interferon beta-1a, irbesartan, iseganan hydrochloride; L-758298, lamivudine, lanoteplase, leflunomide, leuprorelin acetate, loratadine, losartan potassium; Melagatran, metformin hydrochloride, methotrexate, metronidazole, micafungin sodium, mitoxantrone hydrochloride; Nelfinavir mesilate, neutral insulin injection, nizatidine; Olopatadine hydrochloride, omeprazole, ondansetron hydrochloride; Pamidronate sodium, paracetamol, paroxetine hydrochloride, perindopril, pimecrolimus, pioglitazone hydrochloride, piroxicam, pleconaril, pralmorelin, pravastatin sodium, prednisolone, prednisone, propofol; Raloxifene hydrochloride, ranpirnase, remifentanil hydrochloride, risedronate sodium, risperidone, rofecoxib, ropinirole

  19. Gateways to clinical trials.

    PubMed

    Moral, M A; Tomillero, A

    2008-03-01

    Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: 131-I-Chlorotoxin, 423557; Abatacept, Ad.Egr.TNF.11D, Adalimumab, AE-941, Ambrisentan, AMR-001, Anacetrapib, Anakinra, Aripiprazole, Atazanavir sulfate; BAY-639044, Bazedoxifene acetate, Belimumab, Bevacizumab, Bortezomib, Botulinum toxin type B, Brivaracetam, Bucindolol hydrochloride; Carfilzomib, Carisbamate, CCX-282, CD20Bi, Ceftobiprole, Certolizumab pegol, CF-101, Cinacalcet hydrochloride, Cypher; Darifenacin hydrobromide, Degarelix acetate, Denosumab, Desvenlafaxine succinate, Dexlansoprazole, Dexverapamil, Drotrecogin alfa (activated), Duloxetine hydrochloride, Dutasteride; Efalizumab, EPs-7630, Escitalopram oxalate, Etoricoxib; Fluticasone furoate, Fondaparinux sodium, Fospropofol disodium; Hexadecyloxypropyl-cidofovir, HIV gp120/NefTat/AS02A, HPV-6/11/16/18; INCB-18424, Incyclinide, Inhalable human insulin, Insulin detemir; KNS-760704, KW-0761; Lacosamide, Lenalidomide, Levetiracetam, Licofelone, Lidocaine/prilocaine; mAb 216, MEDI-528, Men ACWY, Meningococcal C-CRM197 vaccine, Methylnaltrexone bromide; Nemifitide ditriflutate, Nicotine conjugate vaccine, Nilotinib hydrochloride monohydrate; Octaparin; Parathyroid hormone (human recombinant), Pegaptanib octasodium, Pitrakinra, Prasterone, Pregabalin; Ranelic acid distrontium salt, Rasagiline mesilate, Retigabine, Rimonabant, RTS,S/AS02D; Sarcosine, Sitaxentan sodium, Solifenacin succinate, Sunitinib malate; Taranabant, Taxus, Teduglutide, Teriparatide, Ticagrelor, Travoprost, TRU-015; USlipristal acetate, Urocortin 2; Vardenafil hydrochloride hydrate; YM-155, Yttrium 90 (90Y) ibritumomab tiuxetan; Zanolimumab, Zoledronic acid monohydrate, Zotarolimus

  20. Gateways to Clinical Trials.

    PubMed

    Bayes, M; Rabasseda, X; Prous, J R

    2002-04-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Studies knowledge area of Prous Science Integrity, the world's first drug discovery and development portal, and provides information on study design, treatments, conclusions and references. This issue focuses on the following selection of drugs: Abiciximab, acetylcholine chloride, acetylcysteine, alefacept, alemtuzumab, alicaforsen, alteplase, aminopterin, amoxicillin sodium, amphotericin B, anastrozole, argatroban monohydrate, arsenic trioxide, aspirin, atazanavir, atorvastatin, augmerosen, azathioprine; Benzylpenicillin, BMS-284756, botulinum toxin type A, botulinum toxin type B, BQ-123, budesonide, BXT-51072; Calcium folinate, carbamazepine, carboplatin, carmustine, ceftriaxone sodium, cefuroxime axetil, chorionic gonadotropin (human), cimetidine, ciprofloxacin hydrochloride, cisplatin, citalopram hydrobromide, cladribine, clarithromycin, clavulanic acid, clofarabine, clopidogrel hydrogensulfate, clotrimazole, CNI-1493, colesevelam hydrochloride, cyclophosphamide, cytarabine; Dalteparin sodium, daptomycin, darbepoetin alfa, debrisoquine sulfate, dexrazoxane, diaziquone, didanosine, docetaxel, donezepil, doxorubicin hydrochloride liposome injection, DX-9065a; Eberconazole, ecogramostim, eletriptan, enoxaparin sodium, epoetin, epoprostenol sodium, erlizumab, ertapenem sodium, ezetimibe; Fampridine, fenofibrate, filgrastim, fluconazole, fludarabine phosphate, fluorouracil, 5-fluorouracil/epinephrine, fondaparinux sodium, formoterol fumarate; Gabapentin, gemcitabine, gemfibrozil, glatiramer; Heparin sodium, homoharringtonine; Ibuprofen, iloprost, imatinib mesilate, imiquimod, interferon alpha-2b, interferon alpha-2c, interferon-beta; KW-6002; Lamotrigine, lanoteplase, metoprolol tartrate, mitoxantrone hydrochloride; Naproxen sodium, naratriptan, Natalizumab, nelfinavir mesilate

  1. Gateways to clinical trials.

    PubMed

    Bayes, M; Rabasseda, X; Prous, J R

    2006-12-01

    Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: 5-Methyltetrahydrofolate, 9-aminocamptothecin; AdPEDF.11, AE-37, albumin interferon alfa, alicaforsen sodium, alvocidib hydrochloride, AMG-706, arginine butyrate, avanafil, axitinib, azimilide hydrochloride; BAY-579352, belagenpumatucel-L, beta-lapachone, BHT-3009, BIBW-2992, bremelanotide, BX-471; Casopitant mesylate, cediranib, certolizumab pegol, CH-1504, ChimeriVax-West Nile, clofazimine, CpG-7909, curcumin, Cypher; Dapoxetine hydrochloride, darusentan, diflomotecan, D-methionine, dnaJP1, D-serine, DTPw-HB Hib-MenAC, DTPw-HepB-Hib; E-7010, ecogramostim, edodekin alfa, EGFRvlll peptide vaccine, elcometrine, elcometrine/ethinylestradiol, elsilimomab, enrasentan, ertumaxomab, etalocib sodium, exisulind; Fenretinide, fesoterodine, fingolimod hydrochloride, fontolizumab; Gefitinib, gemtuzumab ozogamicin, ghrelin (human), GV-1001; HTU-PA, human papillomavirus vaccine; Indacaterol, indiplon, interleukin-21, intranasal insulin, irinotecan hydrochloride/floxuridine, ISIS-301012, ispinesib mesylate, ixabepilone; K562/GM-CSF; Lapatinib, L-BLP-25, linezolid, liposome encapsulated paclitaxel, LY-2124275; MC-1, MC-1/lisinopril, MDX-066, melanoma vaccine, MMR-V, multivalent (ACYW) meningitis vaccine; Nilotinib, nobori, nociceptin; Oblimersen sodium, orbofiban acetate, ospemifene; Paliperidone, panitumumab, PEG-filgrastim, PEGylated interferon alfacon-1, perflubutane, pertuzumab, phenserine tartrate, phVEGF-A165, pleconaril, prasugrel, prednisolone sodium metasulfobenzoate; R-411, recombinant malaria vaccine, rhGM-CSF, roflumilast, romidepsin, ruboxistaurin mesilate hydrate; Sirolimus-eluting stent, SR-4554, St. John

  2. Gateways to clinical trials.

    PubMed

    Bayés, M; Rabasseda, X; Prous, J R

    2004-04-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Studies Knowledge Area of Prous Science Integrity(R), the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: ABI-007, adalimumab, adefovir dipivoxil, alefacept, alemtuzumab, 3-AP, AP-12009, APC-8015, L-Arginine hydrochloride, aripiprazole, arundic acid, avasimibe; Bevacizumab, bivatuzumab, BMS-181176, BMS-184476, BMS-188797, bortezomib, bosentan, botulinum toxin type B, BQ-123, BRL-55730, bryostatin 1; CEP-1347, cetuximab, cinacalcet hydrochloride, CP-461, CpG-7909; D-003, dabuzalgron hydrochloride, darbepoetin alfa, desloratadine, desoxyepothilone B, dexmethylphenidate hydrochloride, DHA-paclitaxel, diflomotecan, DN-101, DP-b99, drotrecogin alfa (activated), duloxetine hydrochloride, duramycin; Eculizumab, Efalizumab, EKB-569, elcometrine, enfuvirtide, eplerenone, erlotinib hydrochloride, ertapenem sodium, eszopiclone, everolimus, exatecan mesilate, ezetimibe; Fenretinide, fosamprenavir calcium, frovatriptan; GD2L-KLH conjugate vaccine, gefitinib, glufosfamide, GTI-2040; Hexyl insulin M2, human insulin, hydroquinone, gamma-Hydroxybutyrate sodium; IL-4(38-37)-PE38KDEL, imatinib mesylate, indisulam, inhaled insulin, ixabepilone; KRN-5500; LY-544344; MDX-210, melatonin, mepolizumab, motexafin gadolinium; Natalizumab, NSC-330507, NSC-683864; 1-Octanol, omalizumab, ortataxel; Pagoclone, peginterferon alfa-2a, peginterferon alfa-2b, pemetrexed disodium, phenoxodiol, pimecrolimus, plevitrexed, polyphenon E, pramlintide acetate, prasterone, pregabalin, PX-12; QS-21; Ragaglitazar, ranelic acid distrontium salt, RDP-58, recombinant glucagon-like peptide-1 (7-36) amide, repinotan hydrochloride, rhEndostatin, rh-Lactoferrin, (R)-roscovitine; S-8184, semaxanib, sitafloxacin hydrate, sitaxsentan sodium, sorafenib, synthadotin

  3. Gateways to clinical trials.

    PubMed

    Bayes, M; Rabasseda, X; Prous, J R

    2004-01-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Trials Know- ledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: ABI-007, Ad.Egr.TNF.11D, adefovir dipivoxil, AdPEDF.11, AES-14, albumex, alefacept, alemtuzumab, aliskiren fumarate, alvimopan hydrate, aAminolevulinic acid hydrochloride, aminolevulinic acid methyl ester, anakinra, anti-IL-12 MAb, aprepitant, atazanavir sulfate, atrasentan, avanafil; Banoxantrone, BG-12, bimatoprost, bortezomib, bosentan; Calcipotriol/betamethasone dipropionate, caspofungin acetate, CBT-1, ciclesonide, clofarabine, conivaptan hydrochloride, CpG-7909, C-Vax, Cypher; DA-8159, DAC:GLP-1, darbepoetin alfa, darifenacin, duloxetine hydrochloride; Eculizumab, efalizumab, efaproxiral sodium, EGF vaccine, eletriptan, epratuzumab, erlotinib hydrochloride, escitalopram oxalate, ETC-642, etoricoxib, everolimus, exenatide; Gefitinib, IV gamma-globulin; Human insulin, gamma-hydroxybutyrate sodium; IDN-6556, iguratimod, imatinib mesylate, indiplon, ixabepilone; Laquinimod, LB-80380, lidocaine/prilocaineliraglutide, lopinavir, lopinavir/ritonavir, lucinactant; MAb-14.18, melatonin, MLN-591-DM1; NC-531, neridronic acid, nesiritide, neutrophil-inhibitory factor, niacin/lovastatin; Oblimersen sodium, olcegepant, oral Insulin, ORV-105; Palonosetron hydrochloride, PAmAb, pegaptanib sodium, peginterferon alfa-2a, pegvisomant, perifosine, pexelizumab, phenoxodiol, phenserine tartrate, pimecrolimus, pramlintide acetate, pregabalin, PRO-542, prostate cancer vaccine, PT-141; Ramelteon, rasagiline mesilate, rDNA insulin, reslizumab, rh-Lactoferrin, ribamidine hydrochloride, rosuvastatin calcium; S-8184l, SC-1, sorafenib, St. John's Wort extract, SU-11248; Taxus, telbivudine, tenofovir disoproxil fumarate, teriparatide

  4. Gateways to clinical trials.

    PubMed

    Bayés, M; Rabasseda, X; Prous, J R

    2005-04-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity. prous.com. This issue focuses on the following selection of drugs: ABX-IL-8, Acclaim, adalimumab, AGI-1067, alagebrium chloride, alemtuzumab, Alequel, Androgel, anti-IL-12 MAb, AOD-9604, aripiprazole, atomoxetine hydrochloride; Biphasic insulin aspart, bosentan, botulinum toxin type B, bovine lactoferrin, brivudine; Cantuzumab mertansine, CB-1954, CDB-4124, CEA-TRICOM, choriogonadotropin alfa, cilansetron, CpG-10101, CpG-7909, CTL-102, CTL-102/CB-1954; DAC:GRF, darbepoetin alfa, davanat-1, decitabine, del-1 Genemedicine, dexanabinol, dextofisopam, dnaJP1, dronedarone hydrochloride, dutasteride; Ecogramostim, eletriptan, emtricitabine, EPI-hNE-4, eplerenone, eplivanserin fumarate, erlotinib hydrochloride, ertapenem sodium, escitalopram oxalate, esomeprazole magnesium, etoricoxib, ezetimibe; Falecalcitriol, fingolimod hydrochloride; Gepirone hydrochloride; HBV-ISS, HSV-2 theracine, human insulin; Imatinib mesylate, Indiplon, insulin glargine, ISAtx-247; L612 HuMAb, levodopa/carbidopa/entacapone, lidocaine/prilocaine, LL-2113AD, lucinactant, LY-156735; Meclinertant, metelimumab, morphine hydrochloride, morphine-6-glucuronide; Natalizumab, nimotuzumab, NX-1207, NYVAC-HIV C; Omalizumab, onercept, osanetant; PABA, palosuran sulfate, parathyroid hormone (human recombinant), parecoxib sodium, PBI-1402, PCK-3145, peginterferon alfa-2a, peginterferon alfa-2b, peginterferon alfa-2b/ribavirin, pemetrexed disodium, pimecrolimus, PINC, pregabalin; Ramelteon, rasagiline mesilate, rasburicase, rimonabant hydrochloride, RO-0098557, rofecoxib, rosiglitazone maleate/metformin hydrochloride; Safinamide mesilate, SHL-749, sitaxsentan sodium, sparfosic acid, SprayGel, squalamine, St. John's Wort

  5. Gateways to clinical trials.

    PubMed

    Bayés, M; Rabasseda, X; Prous, J R

    2003-01-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Studies knowledge area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: 81C6; Adefovir dipivoxil, Agalsidase alfa, AGM-1470, albumin interferon alfa, alefacept, alosetron hydrochloride, anakinra, anti-CTLA-4 Mab, aprepitant, aripiprazole, atazanavir; BAY-43-9006, BBR-3438, beta-L-Fd4C, bimatoprost, bortezomib, bosentanBR96-doxorubicin; Caspofungin acetate, ciclesonide, cilengitide, cilomilast, COL-1621, COL-3, CpG-7909, cyclosporine; DCVax-Brain, dexmethylphenidate hydrochloride, dexosome vaccine (melanoma), donepezil hydrochloride, drotrecogin alfa (activated), DTI-015, [99Tc]-DTPA-mannosyldextran, duloxetine hydrochloride; Emivirine, emtricitabine, entecavir, epothilone B, estradiol-MNP, etonogestrel/etonogestrel/ethinylestradiol, etoricoxib; Febuxostat, fondaparinux sodium, fosamprenavir calcium; Gefitinib, GVS-111; Heparinase I, HspE7, human alpha-glucosidase, human insulin; Imatinib mesylate, INGN-241, interferon alfa B/D hybrid, interferon alfa Biphasix, ISIS-14803; Lanicemine hydrochloride, 1311-lipiodol, liposome-encapsulated mitoxantrone, lixivaptan, lumiracoxib, lupus-AHP, LY-466700; Marimastat, MEN-10755, micafungin sodium; Nitronaproxen, NSC-683864 Omalizumab, oral insulin; Palonosetron hydrochloride, peginterferon alfa-2a, pimecrolimus, pralnacasan, pramlintide acetate, pregabalin, pyrazoloacridine; R-165335, ranolazine, risperidone, RPR-109881;, RSD-1235, Satraplatin, seocalcitol, sertindole, SMART anti-interferon gamma antibody, sulfasalazine; T-138067, TAK-013, tegaserod maleate, telithromycin, tenofovir disoproxil fumarate, teriparatide, tiotropium bromide, tipifarnib, TP-38; Valdecoxib, vatalanib succinate, voriconazole; ZD-9331.

  6. Gateways to clinical trials.

    PubMed

    Bayes, M; Rabasseda, X; Prous, J R

    2005-10-01

    Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: (-)-Epigallocatechin gallate, (Z)-4-hydroxytamoxifen; Ad.muIFN-beta AD-237, adalimumab, adefovir dipivoxil, agalsidase alfa, alemtuzumab, almotriptan, ALVAC vCP1452, alvimopan hydrate, ambrisentan, anakinra, anti-IFN-gamma MAb; Bimatoprost, BMS-188797, BMS-214662, bortezomib, bosentan, bovine lactoferrin; Caffeine, canertinib dihydrochloride, canfosfamide hydrochloride, cannabidiol, caspofungin acetate, cetuximab, cH36, ChimeriVax-JE, ciclesonide, cilansetron, cinacalcet hydrochloride, clopidogrel, CpG-7909, Cypher; Daptomycin, darbepoetin alfa, darifenacin hydrobromide, decitabine, denufosol tetrasodium, Dexamet, diindolemethane, drotrecogin alfa (activated), duloxetine hydrochloride, DX-9065a; E-7010, edaravone, efalizumab, eicosapentaenoic acid/docosahexaenoic acid, elacridar, eletriptan, emtricitabine, epratuzumab, erlotinib hydrochloride, ertapenem sodium, eszopiclone, everolimus, ezetimibe; Fludarabine, fondaparinux sodium; gamma-Hydroxybutyrate sodium, gavestinel sodium, gefitinib, granisetron-Biochronomer; Human Albumin, human insulin; Imatinib mesylate, indiplon, interleukin-2 XL, isatoribine, ISS-1018, i.v. gamma-globulin, ivabradine hydrochloride, ixabepilone; Lanthanum carbonate, L-arginine hydrochloride, liposomal doxorubicin, LY-450139; Magnesium sulfate, melatonin, motexafin gadolinium, mycophenolic acid sodium salt; Natalizumab, nesiritide, niacin/lovastatin; OGX-011, olmesartan medoxomil, omalizumab, ospemifene; PACAP38, panitumumab, parathyroid hormone (human recombinant), parecoxib sodium, patupilone, pegfilgrastim, peginterferon alfa-2a, peginterferon alfa-2b, peginterferon alfa-2b

  7. HOSC DTN Gateway Test Report

    NASA Technical Reports Server (NTRS)

    Pitts, Robert Lee

    2012-01-01

    Goals of this activity: Test the Huntsville Operations Support Center (HOSC) Delay/Disruption Tolerant Networking (DTN) Gateway for operational use Current activity includes: (1) Test the Implementation of a new DTN2 gateway at the HOSC (2) Confirm integration of DTN nodes into the S-band uplink and Ku-band downlink of the ISS for limited use (3) Implement Aggregate Custody Signal to ISS platforms (4) Verify operational support for Colorado University (CU) onboard components (5) Verify ability to support Multi-Purpose End-To- End Robotic Operation Network (METERON) OpsCon-2

  8. Gateways to Learning.

    ERIC Educational Resources Information Center

    Kennedy, Mike

    2002-01-01

    Discusses the factors that educational facilities managers must consider when selecting doors and windows for their buildings. These include finding a balance in terms of security, energy efficiency, accessibility, aesthetics, and durability; cleaning and maintenance; and noise issues. (EV)

  9. Gateways to clinical trials.

    PubMed

    Tomillero, A; Moral, M A

    2008-09-01

    Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com.This issue focuses on the following selection of drugs: ABT-263, AC-2307, Aclidinium bromide, Adefovir dipivoxil, ADH-1, Agatolimod sodium, Alefacept, Aliskiren fumarate, Aminolevulinic acid methyl ester, Anakinra, Apaziquone, Aprepitant, Aripiprazole, ASM-8, Atiprimod hydrochloride, AVE-0277, AVE-1642, AVE-8062, Axitinib, Azacitidine, AZD-0530; Bazedoxifene acetate, Bevacizumab, Bexarotene, BI-2536, Biphasic insulin aspart, BMS-387032, BMS-663513, Bortezomib, BQ-123, Brivanib alaninate, BSI-201; Caspofungin acetate, CDX-110, Cetuximab, Ciclesonide, CR-011, Cypher; Daptomycin, Darbepoetin alfa, Dasatinib, Decitabine, Deferasirox, Denosumab, Dexlansoprazole, Dexmethylphenidate hydrochloride, DNA-Hsp65 vaccine, Dovitinib, Drotrecogin alfa (activated), DTaP-HBV-IPV/Hibvaccine, DTaP-IPV-HB-PRP-T, Duloxetine hydrochloride, Dutasteride; Ecogramostim, Elacytarabine, Emtricitabine, Endothelin, Entecavir, Eplivanserin fumarate, Escitalopram oxalate, Everolimus, Ezetimibe, Ezetimibe/simvastatin; Farletuzumab, Fesoterodine fumarate, Fibrin sealant (human), Fulvestrant; Gefitinib, Gemtuzumab ozogamicin, Glufosfamide, GSK-1562902A; Hib-TT; Imatinib mesylate, IMC-11F8, Imidazoacridinone, IMP-321, INCB-18424, Indiplon, Indisulam, INNO-406, Irinotecan hydrochloride/Floxuridine, ITF-2357, Ixabepilone; KRN-951; Lasofoxifene tartrate; Lenalidomide, LGD-4665, Lonafarnib, Lubiprostone, Lumiliximab; MDX-1100, Melan-A/MART-1/gp100/IFN-alfa, Methyl-CDDO, Metreleptin, MLN-2704, Mycophenolic acid sodium salt; Na-ASP-2, Naproxcinod, Nilotinib hydrochloride monohydrate, NPI-2358; Oblimersen sodium, Odanacatib; Paclitaxel nanoparticles, PAN-811, Panobinostat, PBI-1402, PC-515, Peginterferon alfa

  10. Gateways to clinical trials.

    PubMed

    Bayes, M; Rabasseda, X; Prous, J R

    2006-03-01

    Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: 131I-labetuzumab; Abacavir sulfate, abatacept, adalimumab, ademetionine, adjuvanted influenza vaccine, alefacept, alemtuzumab, amlodipine, amphotericin B, anakinra, aripiprazole, aspirin, axitinib; Betamethasone dipropionate, bevacizumab, biphasic insulin aspart, bortezomib, bosentan, botulinum toxin type B, BQ-123; Calcium folinate, canertinib dihydrochloride, carboplatin, carmustine, cetirizine hydrochloride, cetuximab, cholecalciferol, ciclesonide, ciclosporin, cinacalcet hydrochloride, cisplatin, clarithromycin, clofazimine, cold-adapted influenza vaccine trivalent, CpG-7909; Darbepoetin alfa, darifenacin hydrobromide, DB-289, desloratadine, Dexamet, dicycloverine hydrochloride, dimethyl fumarate, docetaxel, dolastatin 10, drospirenone, drospirenone/estradiol, duloxetine hydrochloride; Ecogramostim, edotecarin, efaproxiral sodium, enalapril maleate, epoetin beta, epoprostenol sodium, epratuzumab, erlotinib hydrochloride, escitalopram oxalate, estradiol, etanercept; Fluconazole, fludarabine phosphate, fluorouracil; Gefitinib, gemcitabine, Ghrelin (human), glibenclamide, glimepiride, GTI-2040; Haloperidol, human insulin, hydrocortisone probutate; Imatinib mesylate, indisulam, influenza vaccine, inhaled insulin, insulin aspart, insulin glulisine, insulin lispro, irinotecan, ispronicline; Lamivudine, lamivudine/zidovudine/abacavir sulfate, lapatinib, letrozole, levocetirizine, lomustine, lonafarnib, lumiracoxib;Magnesium sulfate, MD-1100, melphalan, metformin hydrochloride, methotrexate, metoclopramide hydrochloride, mitiglinide calcium hydrate, monophosphoryl lipid A, montelukast sodium, motexafin gadolinium

  11. Gateways to clinical trials.

    PubMed

    Bayes, M; Rabasseda, X; Prous, J R

    2005-01-01

    Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: (-)-Epigallocatechin gallate; ACP-103, Ad.Egr.TNF.11 D, adalimumab, AF-IL 12, AIDSVAX gp120 B/B, alefacept, alemtuzumab, a-Galactosylceramide, ALVAC vCP 1452, alvimopan hydrate, alvocidib hydrochloride, aminolevulinic acid hydrochloride, aminolevulinic acid methyl ester, anakinra, anidulafungin, antarelix, aprepitant, aripiprazole, arsenic sulfide, asoprisnil, atazanavir sulfate, atomoxetine hydrochloride; Bevacizumab, bimatoprost, BMS-184476, bortezomib, bosentan, botulinum toxin type B, BrachySil, brivudine; Caffeine, calcipotriol/betamethasone dipropionate, cannabidiol, capsaicin for injection, caspofungin acetate, CC-4047, cetuximab, CGP-36742, clofazimine, CpG-7909, Cypher; Darbepoetin alfa, dextromethorphan/quinidine sulfate, dimethylfumarate, dronabinol/cannabidiol, drotrecogin alfa (activated), duloxetine hydrochloride, dutasteride; Ecogramostim, efalizumab, eletriptan, emtricitabine, enfuvirtide, eplerenone, esomeprazole magnesium, estradiol acetate, eszopiclone, etoricoxib, exenatide, ezetimibe, ezetimibe/simvastatin; Fampridine, fondaparinux sodium, fosamprenavir calcium; Gefitinib, GPI-0100; hA 20, HTU-PA, human insulin, HuOKT 3 gamma 1(Ala 234-Ala 235), hyaluronic acid; Icatibant, imatinib mesylate, Indiplon, INKP-100, INKP-102, iodine (I131) tositumomab, istradefylline, IV gamma-globulin, ivabradine hydrochloride, ixabepilone; Lacosamide, landiolol, lanthanum carbonate, lasofoxifene tartrate, LB-80380, lenalidomide, lidocaine/tetracaine, linezolid, liposomal doxorubicin, liposomal vincristine sulfate, lopinavir, lopinavir/ritonavir, lumiracoxib, lurtotecan; Maribavir, morphine glucuronide, MVA-5 T

  12. THE REMOTE SENSING DATA GATEWAY

    EPA Science Inventory

    The EPA Remote Sensing Data Gateway (RSDG) is a pilot project in the National Exposure Research Laboratory (NERL) to develop a comprehensive data search, acquisition, delivery and archive mechanism for internal, national and international sources of remote sensing data for the co...

  13. UAS-NAS Live Virtual Constructive Distributed Environment (LVC): LVC Gateway, Gateway Toolbox, Gateway Data Logger (GDL), SaaProc Software Design Description

    NASA Technical Reports Server (NTRS)

    Jovic, Srboljub

    2015-01-01

    This document provides the software design description for the two core software components, the LVC Gateway, the LVC Gateway Toolbox, and two participants, the LVC Gateway Data Logger and the SAA Processor (SaaProc).

  14. Building Ties: A Mental Health and Aging Project.

    ERIC Educational Resources Information Center

    Grady, Sally C.; Maynard, Charles L.

    1987-01-01

    Describes Building Ties Project, a program that provides comprehensive assistance to local interagency planning committees addressing mental health service needs of older adults, including training program development materials and consultation. Notes that in two years, project activities in 23 counties increased services, improved interagency…

  15. A Science Data Gateway for Environmental Management

    SciTech Connect

    Agarwal, Deborah, A; Faybishenko, Boris; Freedman, Vicky, L; Krishnan, Harinarayan; Kushner, Gary; Lansing, Carina; Porter, Ellen; Romosan, Alexandru; Shoshani, Arie; Wainwright, Haruko; Weidmer, Arthur; Wu, Kesheng

    2015-10-12

    Science data gateways are effective in providing complex science data collections to the world-wide user communities. In this paper we describe a gateway for the Advanced Simulation Capability for Environmental Management (ASCEM) framework. Built on top of established web service technologies, the ASCEM data gateway is specifically designed for environmental modeling applications. Its key distinguishing features include: (1) handling of complex spatiotemporal data, (2) offering a variety of selective data access mechanisms, (3) providing state of the art plotting and visualization of spatiotemporal data records, and (4) integrating seamlessly with a distributed workflow system using a RESTful interface. ASCEM project scientists have been using this data gateway since 2011.

  16. Looking Forward: Community Gateways at Victoria University

    ERIC Educational Resources Information Center

    Mountford, Christine

    2011-01-01

    The mission and values of Victoria University provide the underlying criteria for the development and implementation of the Community Gateways initiative, which aims to transform the lives of those living in the west of Melbourne through the power of further education. Community Gateways takes the university into the community by providing career…

  17. 11. Historic American Buildings Survey, Arthur C. Haskell, Photographer. 1935 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Historic American Buildings Survey, Arthur C. Haskell, Photographer. 1935 (g) Ext- general view, gateway entrance and fence. - Timothy Jackson House, 527 Washington Street, Newton, Middlesex County, MA

  18. The Globus Galaxies Platform. Delivering Science Gateways as a Service

    SciTech Connect

    Madduri, Ravi; Chard, Kyle; Chard, Ryan; Lacinski, Lukasz; Rodriguez, Alex; Sulakhe, Dinanath; Kelly, David; Dave, Utpal; Foster, Ian

    2015-04-29

    We use public cloud computers to host sophisticated scientific data; software is then used to transform scientific practice by enabling broad access to capabilities previously available only to the few. The primary obstacle to more widespread use of public clouds to host scientific software (‘cloud-based science gateways’) has thus far been the considerable gap between the specialized needs of science applications and the capabilities provided by cloud infrastructures. We describe here a domain-independent, cloud-based science gateway platform, the Globus Galaxies platform, which overcomes this gap by providing a set of hosted services that directly address the needs of science gateway developers. The design and implementation of this platform leverages our several years of experience with Globus Genomics, a cloud-based science gateway that has served more than 200 genomics researchers across 30 institutions. Building on that foundation, we have also implemented a platform that leverages the popular Galaxy system for application hosting and workflow execution; Globus services for data transfer, user and group management, and authentication; and a cost-aware elastic provisioning model specialized for public cloud resources. We describe here the capabilities and architecture of this platform, present six scientific domains in which we have successfully applied it, report on user experiences, and analyze the economics of our deployments. Published 2015. This article is a U.S. Government work and is in the public domain in the USA.

  19. GATEWAY - COMMUNICATIONS GATEWAY SOFTWARE FOR NETEX, DECNET, AND TCP/IP

    NASA Technical Reports Server (NTRS)

    Keith, B.

    1994-01-01

    The Communications Gateway Software, GATEWAY, provides process-to-process communication between remote applications programs in different protocol domains. Communicating peer processes may be resident on any paired combination of NETEX, DECnet, or TCP/IP hosts. The gateway provides the necessary mapping from one protocol to another and will facilitate practical intermachine communications in a cost effective manner by eliminating the need to standardize on a single protocol or the need to implement multiple protocols in the host computers. The purpose of the gateway is to support data transfers between application programs on different host computers using different protocols. The gateway computer must be physically connected to both host computers and must contain the system software needed to use the communication protocols of both host computers. The communication process between application partners can be divided into three phases: session establishment, data transfer, and session termination. The communication protocols supported by GATEWAY (DECnet, NETEX, and TCP/IP) have addressing mechanisms that allow an application to identify itself and distinguish among other applications on the network. The exact form of the address varies depending on whether an application is passively offering (awaiting the receipt of a network connection from another network application) or actively connecting to another network. When the gateway is started, GATEWAY reads a file of address pairs. One of the address pairs is used by GATEWAY for passively offering on one network while the other address in the pair is used for actively connecting on the other network establishing the session. Now the two application partners can send and receive data in a manner appropriate to their home networks. GATEWAY accommodates full duplex transmissions. Thus, if the application partners are sophisticated enough, they can send and receive simultaneously. GATEWAY also keeps track of the number

  20. Gateway design specification for fiber optic local area networks

    NASA Technical Reports Server (NTRS)

    1985-01-01

    This is a Design Specification for a gateway to interconnect fiber optic local area networks (LAN's). The internetworking protocols for a gateway device that will interconnect multiple local area networks are defined. This specification serves as input for preparation of detailed design specifications for the hardware and software of a gateway device. General characteristics to be incorporated in the gateway such as node address mapping, packet fragmentation, and gateway routing features are described.

  1. Capitalizing on Experience with Intelligence Gateway Software.

    DTIC Science & Technology

    1988-01-01

    available on DGIS are discussed below. A Gateway User Support and Training Office ( GUSTO ) has also been established. GUSTO staff members provide a...terminal, a telecommunications link, or the remote system) and take action to have the problem resolved. Users may also contact the GUSTO staff via...Friendly Information Retrieval SysTem USERS GUSTO = Gateway User Support and Training Office HSDB = Hazardous Substances Data Bank IAC = Information

  2. Bridging network divides: building capacity to support aging with disability populations through research.

    PubMed

    Putnam, Michelle

    2014-01-01

    Federal and state efforts to rebalance long-term services and supports (LTSS) in favor of home and community based over institutional settings has helped create structural bridges between the historically separated aging and disability LTSS networks by integrating and/or linking aging and disability systems. These changes present new opportunities to study bridging mechanisms and program related outcomes at national and local levels through federally sponsored LTSS initiatives termed Rebalancing programs. Rebalancing programs also offer opportunities to explore and understand the capacity of LTSS networks (age integrated or linked aging and disability systems) to serve aging with disability populations, persons who live with long-term chronic conditions or impairments such as multiple sclerosis, spinal cord injury, intellectual or developmental disabilities. To date, there is limited evidence based LTSS program and practice knowledge about this heterogeneous population such as met and unmet needs or interventions to support healthy aging. Efforts that center on bridging the larger fields of aging and disability in order to build new knowledge and engage in knowledge translation and translational research are critical for building capacity to support persons aging with disability in LTSS. Generating the investment in bridging aging and disability research across stakeholder group, including researchers and funders, is vital for these efforts.

  3. Engaging the University in Building Communities of Practice for Aging in Place

    ERIC Educational Resources Information Center

    McDonald, Jessyna M.

    2011-01-01

    Based upon the principles of the Engaged University (Kellogg Commission 2001), The Institute of Gerontology (IOG) at the University of the District of Columbia developed a model for the scholarship of engagement by building communities of practice within the aging network which may support and enhance student learning outcomes and experiences. The…

  4. Earth Observing System Data Gateway

    NASA Technical Reports Server (NTRS)

    Pfister, Robin; McMahon, Joe; Amrhein, James; Sefert, Ed; Marsans, Lorena; Solomon, Mark; Nestler, Mark

    2006-01-01

    The Earth Observing System Data Gateway (EDG) software provides a "one-stop-shopping" standard interface for exploring and ordering Earth-science data stored at geographically distributed sites. EDG enables a user to do the following: 1) Search for data according to high-level criteria (e.g., geographic location, time, or satellite that acquired the data); 2) Browse the results of a search, viewing thumbnail sketches of data that satisfy the user s criteria; and 3) Order selected data for delivery to a specified address on a chosen medium (e.g., compact disk or magnetic tape). EDG consists of (1) a component that implements a high-level client/server protocol, and (2) a collection of C-language libraries that implement the passing of protocol messages between an EDG client and one or more EDG servers. EDG servers are located at sites usually called "Distributed Active Archive Centers" (DAACs). Each DAAC may allow access to many individual data items, called "granules" (e.g., single Landsat images). Related granules are grouped into collections called "data sets." EDG enables a user to send a search query to multiple DAACs simultaneously, inspect the resulting information, select browseable granules, and then order selected data from the different sites in a seamless fashion.

  5. 47 CFR 10.310 - Federal alert gateway. [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Federal alert gateway. 10.310 Section 10.310 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM System Architecture § 10.310 Federal alert gateway....

  6. 47 CFR 10.310 - Federal alert gateway. [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Federal alert gateway. 10.310 Section 10.310 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL WIRELESS EMERGENCY ALERTS System Architecture § 10.310 Federal alert gateway....

  7. 47 CFR 10.310 - Federal alert gateway. [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Federal alert gateway. 10.310 Section 10.310 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM System Architecture § 10.310 Federal alert gateway....

  8. 47 CFR 10.310 - Federal alert gateway. [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Federal alert gateway. 10.310 Section 10.310 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL WIRELESS EMERGENCY ALERTS System Architecture § 10.310 Federal alert gateway....

  9. 47 CFR 10.310 - Federal alert gateway. [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Federal alert gateway. 10.310 Section 10.310 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM System Architecture § 10.310 Federal alert gateway....

  10. Aging management program of the reactor building concrete at Point Lepreau Generating Station

    NASA Astrophysics Data System (ADS)

    Aldea, C.-M.; Shenton, B.; Demerchant, M. M.; Gendron, T.

    2011-04-01

    In order for New Brunswick Power Nuclear (NBPN) to control the risks of degradation of the concrete reactor building at the Point Lepreau Generating Station (PLGS) the development of an aging management plan (AMP) was initiated. The intention of this plan was to determine the requirements for specific structural components of concrete of the reactor building that require regular inspection and maintenance to ensure the safe and reliable operation of the plant. The document is currently in draft form and presents an integrated methodology for the application of an AMP for the concrete of the reactor building. The current AMP addresses the reactor building structure and various components, such as joint sealant and liners that are integral to the structure. It does not include internal components housed within the structure. This paper provides background information regarding the document developed and the strategy developed to manage potential degradation of the concrete of the reactor building, as well as specific programs and preventive and corrective maintenance activities initiated.

  11. A Descriptive Review of the Gateway Grants Program.

    ERIC Educational Resources Information Center

    Research Triangle Inst., Research Triangle Park, NC. Center for Research in Education.

    The purpose of this study was to develop a description of the Gateway Grants Program, providing data on the activities that states and Gateway Grantees have undertaken in response to the Adult Education Act, as amended. Information was gathered through a survey of state officials administering the Gateway program and local directors of Gateway…

  12. 47 CFR 10.320 - Provider alert gateway requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Section 10.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM System Architecture § 10.320 Provider alert gateway requirements. This section specifies the functions... protocols between the Federal alert gateway and the CMS provider gateway. (d) Geographic targeting. The...

  13. Open Smart Energy Gateway (OpenSEG)

    SciTech Connect

    2014-09-01

    The Open Smart Energy Gateway (OpenSEG) aims to provide near-real time smart meter data to consumers without the delays or latencies associated with it being transported to the utility data center and then back to the consumer's application. To do this, the gateway queries the local Smart Meter to which it is bound to get energy consumption information at pre-defined intervals (minimum interval is 4 seconds). OpenSEG then stores the resulting data internally for retrieval by an external application.

  14. VO-compliant workflows and science gateways

    NASA Astrophysics Data System (ADS)

    Castelli, G.; Taffoni, G.; Sciacca, E.; Becciani, U.; Costa, A.; Krokos, M.; Pasian, F.; Vuerli, C.

    2015-06-01

    Workflow and science gateway technologies have been adopted by scientific communities as a valuable tool to carry out complex experiments. They offer the possibility to perform computations for data analysis and simulations, whereas hiding details of the complex infrastructures underneath. There are many workflow management systems covering a large variety of generic services coordinating execution of workflows. In this paper we describe our experiences in creating workflows oriented science gateways based on gUSE/WS-PGRADE technology and in particular we discuss the efforts devoted to develop a VO-compliant web environment.

  15. EPA Remote Sensing Information Gateway

    NASA Astrophysics Data System (ADS)

    Paulsen, H. K.; Szykman, J. J.; Plessel, T.; Freeman, M.; Dimmick, F.

    2009-12-01

    The Remote Sensing Information Gateway was developed by the U.S. Environmental Protection Agency (EPA) to assist researchers in easily obtaining and combining a variety of environmental datasets related to air quality research. Current datasets available include, but are not limited to surface PM2.5 and O3 data, satellite derived aerosol optical depth , and 3-dimensional output from U.S. EPA's Models 3/Community Multi-scale Air Quality (CMAQ) modeling system. The presentation will include a demonstration that illustrates several scenarios of how researchers use the tool to help them visualize and obtain data for their work; with a particular focus on episode analysis related to biomass burning impacts on air quality. The presentation will provide an overview on how RSIG works and how the code has been—and can be—adapted for other projects. One example is the Virtual Estuary, which focuses on automating the retrieval and pre-processing of a variety of data needed for estuarine research. RSIG’s source codes are freely available to researchers with permission from the EPA principal investigator, Dr. Jim Szykman. RSIG is available to the community and can be accessed online at http://www.epa.gov/rsig. Once the JAVA policy file is configured on your computer you can run the RSIG applet on your computer and connect to the RSIG server to visualize and retrieve available data sets. The applet allows the user to specify the temporal/spatial areas of interest, and the types of data to retrieve. The applet then communicates with RSIG subsetter codes located on the data owners’ remote servers; the subsetter codes assemble and transfer via ordinary Internet protocols only the specified data to the researcher’s computer. This is much faster than the usual method of transferring large files via FTP and greatly reduces network traffic. The RSIG applet then visualizes the transferred data on a latitude-longitude map, automatically locating the data in the correct

  16. Role of Marine Gateways in the Paleoceanography of the Miocene Mediterranean Sea; A Model Study

    NASA Astrophysics Data System (ADS)

    de la Vara, A.; Meijer, P. T.

    2015-12-01

    During the Miocene, due to the convergence of the African plate and the Eurasian plate, the Mediterranean region was subject to profound paleogeographic changes. The evolving coastline and bathymetry of the Mediterranean Sea and, in particular, the opening and closure of the marine connections between the Mediterranean and the outside oceans, triggered important changes in Mediterranean circulation and, indirectly, also affected the global-scale ocean circulation. Until about the Middle Miocene the proto-Mediterranean Sea was open to the Indo-Pacific Ocean through the so-called Indian Gateway. Although the exact age of closure of this gateway is still debated, it is accepted that it substantially affected the paleoceanography of the Mediterranean Sea. Later in time, during the Late Miocene, the Mediterranean was only connected to the Atlantic Ocean but by two marine corridors: the Betic and Rifian corridors. Closure of these narrow passages resulted in the Messinian Salinity Crisis, during which a sequence of evaporites was deposited throughout the Mediterranean basin. In this work we use a regional-scale ocean general circulation model (the Princeton Ocean Model) to gain insight into the role of the evolving gateways. The analysis focuses on large-scale (overturning) circulation, patterns of exchange in the gateways and properties of the Mediterranean water. By comparing our model results to geological data we are able to propose new scenarios or rule out previously proposed ones, and determine the conditions evidenced by the geological observations. More specifically we investigate two different topics: (i) the effects of shoaling and closure of the Indian Gateway and (ii) the functioning of the Late Miocene double gateway to the Atlantic.

  17. Gateway's Horizon: A Center of Excellence

    ERIC Educational Resources Information Center

    Herring, Jayne; Colony, Lee

    2007-01-01

    This article describes Gateway Technical College's Horizon Center for Transportation Technology, located in Kenosha, Wisconsin, which was the product of collaboration with business and industry, community support and a U.S. Department of Labor (DOL) grant. The center, which opened this fall, is a prime example of a sustainable community…

  18. Predicting Success in a Gateway Mathematics Course

    ERIC Educational Resources Information Center

    Morrison, Michael C.; Schmit, Shelly

    2010-01-01

    A logit model predicting student outcomes for a gateway course, Math for Liberal Arts, was successfully developed which fits the data well. Two variables, ACT math score and high school GPA, were found to be significant predictors of achieving a C or better in Math for Liberal Arts. A practical implication of the study suggests that with just two…

  19. Calculus ABCs: A Gateway for Freshman Calculus

    ERIC Educational Resources Information Center

    Fulton, Scott R.

    2003-01-01

    This paper describes a gateway testing program designed to ensure that students acquire basic skills in freshman calculus. Students must demonstrate they have mastered standards for "Absolutely Basic Competency"--the Calculus ABCs--in order to pass the course with a grade of C or better. We describe the background, standards, and testing program.…

  20. "Gateway" Districts Struggle to Serve Immigrant Parents

    ERIC Educational Resources Information Center

    Maxwell, Lesli A.

    2012-01-01

    As thousands of communities--especially in the South--became booming gateways for immigrant families during the 1990s and the early years of the new century, public schools struggled with the unfamiliar task of serving the large numbers of English-learners arriving in their classrooms. Instructional programs were built from scratch. Districts had…

  1. SEDAC information gateway plan V(1)

    NASA Technical Reports Server (NTRS)

    Chen, Robert S. (Compiler)

    1995-01-01

    This annual update of the Information Gateway Plan incorporates changes recommended by the Socioeconomic Data and Applications Center (SEDAC) User Working Group (UWG) and reflects comments and suggestions from users, collaborators, and the Contracting Officer Technical Representative (COTR). The Information Gateway Plan is a concise and specific plan that outlines SEDAC activities and services in support of the earth and social sciences and other user communities. The SEDAC Information Gateway effort is a primary means by which the Earth Observing System Data and Information System (EOSDIS) can link meaningfully with a broad range of social science data sources and users in ways that lead to tangible benefits to the American people. The SEDAC Information Gateway provides interdisciplinary access to socioeconomic and physical science data and information resources held by SEDAC and numerous other institutions and networks around the world. The Plan describes the areas of research of earth scientists and socioeconomic scientists where interchange of data and information is most needed. It sets guidelines for the continued development of SEDAC's directory of social science datasets and establishes priorities for efforts to make data held by SEDAC or accessible through SEDAC available to the user community. The Plan also describes the means by which the SEDAC user community can access information products specified by the SEDAC Data and Applications Development Plan (DADP). Among other major activities, SEDAC will continue to enhance and operate a directory capability, interoperable with the Global Change Master Directory, that provides the socioeconomic community with information about earth science products and the earth science research community with information about socioeconomic data. The Information Gateway also serves as a unique and powerful access pathway for a wide range of users and potential users of socioeconomic and earth science data, including

  2. A Robotic Communications Gateway for Ocean Observations

    NASA Astrophysics Data System (ADS)

    Orcutt, J. A.; Berger, J.; Laske, G.; Babcock, J.

    2015-12-01

    We describe a new technology that can provide real-time telemetry of sensor data from the ocean bottom. The breakthrough technology that makes this system possible is an autonomous surface vehicle called the Wave Glider developed by Liquid Robotics, Inc. of Sunnyvale, CA., which harvests wave and solar energy for motive and electrical power. The free-floating surface communications gateway uses a Liquid Robotics wave glider comprising a surfboard-sized float towed by a tethered, submerged glider, which converts wave motion into thrust. For navigation, the wave glider is equipped with a small computer, a GPS receiver, a rudder, solar panels and batteries, and an Iridium satellite modem. Acoustic communications connect the subsea instruments and the surface gateway while communications between the gateway and land are provided by the Iridium satellite constellation. Wave gliders have demonstrated trans-oceanic range and long-term station keeping capabilities. The topside acoustics communications package is mounted in a shallow tow body, which uses a WHOI micro modem and a Benthos low frequency, directional transducer. A matching bottom side modem and transducer are mounted on the ocean bottom package. Tests of the surface gateway in 4000 m of water demonstrated an acoustic efficiency of approximately 256 bits/J. For example, it has the ability to send four channels of compressed, one sample per second data from the ocean bottom to the gateway with an average power draw of approximately 0.36 W and a latency of about three minutes. This gateway is used to send near-real-time data from a broadband ocean bottom seismic observatory; we are presently designing and constructing a seafloor package with a two-year operational life. We have found that for frequencies f where f<10mHz, 35mHz < f < 120mHz and f>~3Hz, the vertical component, seafloor system noise characteristics are generally superior to similar observatories on land. Increasing the density of these stations over

  3. Indoor air quality investigation according to age of the school buildings in Korea.

    PubMed

    Sohn, Jongryeul; Yang, Wonho; Kim, Jihwan; Son, Busoon; Park, Jinchul

    2009-01-01

    Since the majority of schools are housed in buildings dating from the 1960s and 1970s, a comprehensive construction and renovation program of school buildings has been carried out to improve the educational conditions in Korea. However, classrooms and computer rooms, with pressed wood desks, chairs and furnishings, as well as construction materials, might have negative effects on the indoor air quality. Furthermore, most schools have naturally ventilated classrooms. The purpose of this study was to characterize the concentrations of different indoor air pollutants within Korean schools and to compare their indoor levels within schools according to the age of school buildings. Indoor and outdoor air samples of carbon monoxide (CO), carbon dioxide (CO(2)), particulate matter (PM(10)), total microbial count (TBC), total volatile organic compounds (TVOCs) and formaldehyde (HCHO) were obtained during summer, autumn and winter from three sites; a classroom, a laboratory and a computer classroom at 55 different schools. The selection of the schools was based on the number of years since the schools had been constructed. The problems causing indoor air pollution at the schools were chemicals emitted by building materials or furnishings, and insufficient ventilation rates. The I/O ratio for HCHO was 6.32 during the autumn, and the indoor HCHO concentrations (mean = 0.16 ppm) in schools constructed within 1 year were significantly higher than the Korean Indoor Air Standard, indicating that schools have indoor sources of HCHO. Therefore, increasing the ventilation rate by means of a mechanical system and the use of low-emission furnishings can play key roles in improving the indoor air quality within schools.

  4. BASSET: Scalable Gateway Finder in Large Graphs

    SciTech Connect

    Tong, H; Papadimitriou, S; Faloutsos, C; Yu, P S; Eliassi-Rad, T

    2010-11-03

    Given a social network, who is the best person to introduce you to, say, Chris Ferguson, the poker champion? Or, given a network of people and skills, who is the best person to help you learn about, say, wavelets? The goal is to find a small group of 'gateways': persons who are close enough to us, as well as close enough to the target (person, or skill) or, in other words, are crucial in connecting us to the target. The main contributions are the following: (a) we show how to formulate this problem precisely; (b) we show that it is sub-modular and thus it can be solved near-optimally; (c) we give fast, scalable algorithms to find such gateways. Experiments on real data sets validate the effectiveness and efficiency of the proposed methods, achieving up to 6,000,000x speedup.

  5. The Thames Gateway: planning policy and flood risk scenarios

    NASA Astrophysics Data System (ADS)

    Eldridge, Jillian; Horn, Diane

    2010-05-01

    The Thames Gateway, currently Europe's largest regeneration project, presents a valuable case study area in which to examine the interrelated issues of planning policy, flood risk and insurance loss potential. The region is typified by a significant exposure to flooding due to its location, which as developments proceed, could result in increased areas of vulnerability with consequential insurance loss and hotspots of risk. With 160,000 new homes planned by 2016, positive use of planning policy is fundamental in minimising potential flood risk as well as ensuring long term economic and social goals can be met. This project focuses on several planning scenarios within the Gateway for the areas of Barking and Medway, and models flood risk using a commercial flood model to develop the flood risk under alternative planning policy scenarios. The two areas chosen demonstrate major regeneration and redevelopment sites located on Thames tidal floodplain. The areas are protected by flood defences although are both downstream of the Thames Barrier. However, it is expected that defences will be maintained and upgraded over the next several years, particularly in the Medway, which is currently protected to a lower level than most other areas in the Thames Gateway. The progress of development is more advanced in Barking with the major regeneration site, Barking Riverside, hosting 2000 new homes. The study sites have been chosen based on their location and proximity to the Thames and allow for an analysis of planning policy and its influence in minimising risk into the future. The reflected change in flood risk due to both the planned developments and flood defences will help to understand change in risk over time and the intricacies expected with delivering planning policy in a multi-governed area subject to conflicting objectives. Flood risk for both sites are modelled using a commercial flood model to estimate flood risk based on several flood scenarios for both current and

  6. Neutron Science TeraGrid Gateway

    NASA Astrophysics Data System (ADS)

    Lynch, Vickie; Chen, Meili; Cobb, John; Kohl, Jim; Miller, Steve; Speirs, David; Vazhkudai, Sudharshan

    2010-11-01

    The unique contributions of the Neutron Science TeraGrid Gateway (NSTG) are the connection of national user facility instrument data sources to the integrated cyberinfrastructure of the National Science FoundationTeraGrid and the development of a neutron science gateway that allows neutron scientists to use TeraGrid resources to analyze their data, including comparison of experiment with simulation. The NSTG is working in close collaboration with the Spallation Neutron Source (SNS) at Oak Ridge as their principal facility partner. The SNS is a next-generation neutron source. It has completed construction at a cost of 1.4 billion and is ramping up operations. The SNS will provide an order of magnitude greater flux than any previous facility in the world and will be available to all of the nation's scientists, independent of funding source, on a peer-reviewed merit basis. With this new capability, the neutron science community is facing orders of magnitude larger data sets and is at a critical point for data analysis and simulation. There is a recognized need for new ways to manage and analyze data to optimize both beam time and scientific output. The TeraGrid is providing new capabilities in the gateway for simulations using McStas and a fitting service on distributed TeraGrid resources to improved turnaround. NSTG staff are also exploring replicating experimental data in archival storage. As part of the SNS partnership, the NSTG provides access to gateway support, cyberinfrastructure outreach, community development, and user support for the neutron science community. This community includes not only SNS staff and users but extends to all the major worldwide neutron scattering centers.

  7. An Interactive, Integrated, Instructional Pathway to the LEAD Science Gateway

    NASA Astrophysics Data System (ADS)

    Yalda, S.; Clark, R.; Davis, L.; Wiziecki, E. N.

    2008-12-01

    of learning materials, as well as new tools and features, to enhance the appearance and use of the LEAD portal gateway and its underlying cyberinfrastructure in an educational setting. The development of educational materials has centered on promoting the accessibility and use of meteorological data and analysis tools through the LEAD portal by providing instructional materials, additional custom designed tools that build off of Unidata's Integrated Data Viewer (IDV) (e.g. IDV Basic and NCDestroyer), and an interactive component that takes the user through specific tasks utilizing multiple tools. In fact, select improvements to parameter lists and domain subsetting have inspired IDV developers to incorporate changes in IDV revisions that are now available to the entire community. This collection of materials, demonstrations, interactive guides, student exercises, and customized tools, which are now available to the educator and student through the LEAD portal gateway, can serve as an instructional pathway for a set of guided, phenomenon-based exercises (e.g. fronts, lake-effect snows, etc.). This paper will provide an overview of the LEAD education and outreach efforts with a focus on the design of Web-based educational materials and instructional approaches for user interaction with the LEAD portal gateway and the underlying cyberinfrastructure, and will encourage educators, especially those involved in undergraduate meteorology education, to begin incorporating these capabilities into their course materials.

  8. 47 CFR 10.320 - Provider alert gateway requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Provider alert gateway requirements. 10.320 Section 10.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL WIRELESS EMERGENCY ALERTS System Architecture § 10.320 Provider alert gateway requirements. This section specifies the...

  9. 47 CFR 10.320 - Provider alert gateway requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Provider alert gateway requirements. 10.320 Section 10.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL WIRELESS EMERGENCY ALERTS System Architecture § 10.320 Provider alert gateway requirements. This section specifies the...

  10. High-performance parallel interface to synchronous optical network gateway

    DOEpatents

    St. John, Wallace B.; DuBois, David H.

    1996-01-01

    A system of sending and receiving gateways interconnects high speed data interfaces, e.g., HIPPI interfaces, through fiber optic links, e.g., a SONET network. An electronic stripe distributor distributes bytes of data from a first interface at the sending gateway onto parallel fiber optics of the fiber optic link to form transmitted data. An electronic stripe collector receives the transmitted data on the parallel fiber optics and reforms the data into a format effective for input to a second interface at the receiving gateway. Preferably, an error correcting syndrome is constructed at the sending gateway and sent with a data frame so that transmission errors can be detected and corrected in a real-time basis. Since the high speed data interface operates faster than any of the fiber optic links the transmission rate must be adapted to match the available number of fiber optic links so the sending and receiving gateways monitor the availability of fiber links and adjust the data throughput accordingly. In another aspect, the receiving gateway must have sufficient available buffer capacity to accept an incoming data frame. A credit-based flow control system provides for continuously updating the sending gateway on the available buffer capacity at the receiving gateway.

  11. High-performance parallel interface to synchronous optical network gateway

    DOEpatents

    St. John, W.B.; DuBois, D.H.

    1996-12-03

    Disclosed is a system of sending and receiving gateways interconnects high speed data interfaces, e.g., HIPPI interfaces, through fiber optic links, e.g., a SONET network. An electronic stripe distributor distributes bytes of data from a first interface at the sending gateway onto parallel fiber optics of the fiber optic link to form transmitted data. An electronic stripe collector receives the transmitted data on the parallel fiber optics and reforms the data into a format effective for input to a second interface at the receiving gateway. Preferably, an error correcting syndrome is constructed at the sending gateway and sent with a data frame so that transmission errors can be detected and corrected in a real-time basis. Since the high speed data interface operates faster than any of the fiber optic links the transmission rate must be adapted to match the available number of fiber optic links so the sending and receiving gateways monitor the availability of fiber links and adjust the data throughput accordingly. In another aspect, the receiving gateway must have sufficient available buffer capacity to accept an incoming data frame. A credit-based flow control system provides for continuously updating the sending gateway on the available buffer capacity at the receiving gateway. 7 figs.

  12. Environmental Dataset Gateway (EDG) Search Widget

    EPA Pesticide Factsheets

    Use the Environmental Dataset Gateway (EDG) to find and access EPA's environmental resources. Many options are available for easily reusing EDG content in other other applications. This allows individuals to provide direct access to EPA's metadata outside the EDG interface. The EDG Search Widget makes it possible to search the EDG from another web page or application. The search widget can be included on your website by simply inserting one or two lines of code. Users can type a search term or lucene search query in the search field and retrieve a pop-up list of records that match that search.

  13. Environmental Dataset Gateway (EDG) REST Interface

    EPA Pesticide Factsheets

    Use the Environmental Dataset Gateway (EDG) to find and access EPA's environmental resources. Many options are available for easily reusing EDG content in other other applications. This allows individuals to provide direct access to EPA's metadata outside the EDG interface. The EDG REST Interface allows each users to query the catalog through a URL using REST syntax. Accessing individual metadata documents through their REST URLs, or groups of documents that match specific search criteria through a REST-formatted search URL, provides powerful functionality for searching, viewing, and sharing EDG records.

  14. Lessons Learned from Building a High-Assurance Crypto Gateway

    DTIC Science & Technology

    2011-02-01

    acceptable security policy for the ST, for example, Bell-LaPadula or a suitable cryptographic policy. The SFR must correspond to the ST features, advertising ...else, satisfying its advertised claim even in a hostile environment. This confidence must be earned for secure systems, where we consider the...Common Criteria was our “ bible ,” always close by to keep us focused on proper design. Writing the code from the formal specification was

  15. Gateway: An earth orbiting transportation node

    NASA Technical Reports Server (NTRS)

    1988-01-01

    University of Texas Mission Design (UTMD) has outlined the components that a space based transportation facility must include in order to support the first decade of Lunar base buildup. After studying anticipated traffic flow to and from the hub, and taking into account crew manhour considerations, propellant storage, orbital transfer vehicle maintenance requirements, and orbital mechanics, UTMD arrived at a design for the facility. The amount of activity directly related to supporting Lunar base traffic is too high to allow the transportation hub to be part of the NASA Space Station. Instead, a separate structure should be constructed and dedicated to handling all transportation-related duties. UTMD found that the structure (named Gateway) would need a permanent crew of four to perform maintenance tasks on the orbital transfer and orbital maneuvering vehicles and to transfer payload from launch vehicles to the orbital transfer vehicles. In addition, quarters for 4 more persons should be allocated for temporary accommodation of Lunar base crew passing through Gateway. UTMD was careful to recommend an expendable structure that can adapt to meet the growing needs of the American space program.

  16. Building a Global Community of Policymakers, Researchers and Educators to Move Education Systems into the Digital Age

    ERIC Educational Resources Information Center

    Voogt, J.; Knezek, G.

    2013-01-01

    The EDUsummIT 2011 aimed to develop (a) recommendations for policy, practice and research that will help educational systems move into the digital age and (b) strategies to build a global community of researchers, policymakers and teachers in the field of Information and Communication Technology (ICT) in Education. Thematic working groups…

  17. The Development of Logico-Mathematical Knowledge in a Block-Building Activity at Ages 1-4

    ERIC Educational Resources Information Center

    Kamii, Constance; Miyakawa, Yoko; Kato, Yasuhiko

    2004-01-01

    To study the developmental interrelationships among various aspects of logico-mathematical knowledge, 80 one- to 4-year-olds were individually asked to build "something tall" with 20 blocks. Percentages of new and significant behaviors increased with age and were analyzed in terms of the development of logico-mathematical relationships. It was…

  18. High-Performance Satellite/Terrestrial-Network Gateway

    NASA Technical Reports Server (NTRS)

    Beering, David R.

    2005-01-01

    A gateway has been developed to enable digital communication between (1) the high-rate receiving equipment at NASA's White Sands complex and (2) a standard terrestrial digital communication network at data rates up to 622 Mb/s. The design of this gateway can also be adapted for use in commercial Earth/satellite and digital communication networks, and in terrestrial digital communication networks that include wireless subnetworks. Gateway as used here signifies an electronic circuit that serves as an interface between two electronic communication networks so that a computer (or other terminal) on one network can communicate with a terminal on the other network. The connection between this gateway and the high-rate receiving equipment is made via a synchronous serial data interface at the emitter-coupled-logic (ECL) level. The connection between this gateway and a standard asynchronous transfer mode (ATM) terrestrial communication network is made via a standard user network interface with a synchronous optical network (SONET) connector. The gateway contains circuitry that performs the conversion between the ECL and SONET interfaces. The data rate of the SONET interface can be either 155.52 or 622.08 Mb/s. The gateway derives its clock signal from a satellite modem in the high-rate receiving equipment and, hence, is agile in the sense that it adapts to the data rate of the serial interface.

  19. Development of ISO connection-oriented/correctionless gateways

    NASA Technical Reports Server (NTRS)

    Landweber, Lawrence H.

    1991-01-01

    The project had two goals, establishment of a gateway between French and U.S. academic networks and studies of issues related to the development of ISO connection-oriented/connectionless (CO/CL) gateways. The first component involved installation of a 56K bps line between Princeton Univ. and INRIA in France. The end-points of these lines were connected by Vitalink link level bridges. The Princeton end was then connected to the NSFNET via the John Von Neumann Supercomputer Center. The French end was connected to Transpac, the French X.25 public data network and to the French IP research internet. U.S. users may communicate with users of the French internet by e-mail and may access computational and data resources in France by use of remote login and file transfer. The connection to Transpac enables U.S. users to access the SIMBAD astronomical database outside of Paris. Access to this database from the U.S. can be via TCP/IP or DECNET (via a DECNET to TCP/IP gateway) protocols utilizing a TCP/IP to X.25 gateway developed and operated by INRIA. The second component of the project involved experiments aimed at understanding the issues involved is ISO CO/CL gateways. An experimental gateway was developed at Wisconsin and a preliminary report was prepared. Because of the need to devote most resources to the first component of the project, work in this area did not go beyond development of a prototype gateway.

  20. The Effectiveness of Gateway Communications in Anti-Marijuana Campaigns

    PubMed Central

    YZER, MARCO C.; CAPPELLA, JOSEPH N.; FISHBEIN, MARTIN; HORNIK, ROBERT; AHERN, R. KIRKLAND

    2014-01-01

    Successful anti-marijuana messages can be hypothesized to have two types of effects, namely persuasion effects, that is, a change in people’s beliefs about using marijuana, and priming effects, that is, a strengthened correlation between beliefs and associated variables such as attitude and intention. This study examined different sets of anti-drug advertisements for persuasion and priming effects. The ads targeted the belief that marijuana is a gateway to stronger drugs, a belief that is often endorsed by campaign planning officials and health educators. A sample of 418 middle and high school students was randomly assigned to a control video or one of three series of ads, two of which included the gateway message in either an explicit or implicit way. Results did not support the use of the gateway belief in anti-marijuana interventions. Whereas no clear persuasion or priming effects were found for any of the ad sequences, there is some possibility that an explicit gateway argument may actually boomerang. In comparison to the control condition, adolescents in the explicit gateway condition tended to agree less with the gateway message and displayed weaker correlations between anti-marijuana beliefs and their attitude toward marijuana use. The results suggest that the gateway message should not be used in anti-drug interventions. PMID:12746037

  1. PAST Gateways (Palaeo-Arctic Spatial and Temporal Gateways): Introduction and overview

    NASA Astrophysics Data System (ADS)

    Ó Cofaigh, Colm; Briner, Jason P.; Kirchner, Nina; Lucchi, Renata G.; Meyer, Hanno; Kaufman, Darrell S.

    2016-09-01

    This special issue relates to the Second International Conference of the PAST Gateways (Palaeo-Arctic Spatial and Temporal Gateways) network which was held in Trieste, Italy in 2014. Twenty five papers are included and they address topics under four main themes: (1) The growth and decay of Arctic ice sheets; (2) Arctic sea ice and palaeoceanography; (3) Terrestrial Arctic environments and permafrost change; and (4) Holocene Arctic environmental change. Geographically the focus is circum-Arctic; the special issue includes detailed regional studies from Greenland, Scandinavia, Russia, and Arctic North America and the adjoining seas, as well as a series of synthesis-type, review papers on Fennoscandian Ice Sheet deglaciation and Holocene Arctic palaeo-climate change. The methodologies employed are diverse and include marine sediment core and geophysical investigations, terrestrial glacial geology and geomorphology, isotopic analysis of ground ice, palaeo-ecological analysis of lacustrine and terrestrial sedimentary archives, geochronology and numerical ice sheet modeling.

  2. Mapping, monitoring, and modeling Western Gateway Community landscape dynamics

    USGS Publications Warehouse

    Hester, David J.

    2013-01-01

    Federal public lands in the western United States are becoming increasingly surrounded by Gateway Communities. These communities are undergoing landscape change due to population growth, economic growth, and the resulting land-use development. Socioeconomic, demographic, and land-use changes in Gateway Communities are often perceived as threats to Federal land resources, natural amenities, cultural resources, and recreational opportunities. However, land-surface disturbances on Federal public lands, such as conventional and alternative energy development (which impact surrounding Gateway Communities), are also environmental and societal issues that Federal land and adjacent regional community planners need to consider in their long-range land-use planning.

  3. Geology of the Gateway quadrangle, Mesa county Colorado

    USGS Publications Warehouse

    Cater, Fred W.

    1953-01-01

    The Gateway quadrangle is one of eighteen 7 1/2-minute quadrangles covering the principal carnotite-producing area of southwestern Colorado. The geology of these quadrangles was mapped by the U.S. Geological Survey for the Atomic Energy Commission as part of a comprehensive study of carnotite deposits. The rocks exposed in the eighteen quadrangles consist of crystalline rocks of pre-Cambrian age and sedimentary rocks that range in age from late Paleozoic to Quaternary. Over much of the area the sedimentary rocks are flat lying, but in places the rocks are disrupted by hih-angle faults, and northwest-trending folds. Conspicuous among the folds are large anticlines having cores of intrusive salt and gypsum. Most of the carnotite deposits are confined to the Salt Wash sandstone member of Jurassic Morrison formation. Within this sandstone, most of the deposits are spottily distributed through an arcuate zone known as "Uruvan Mineral Belt". Individual deposits range in size from irregular masses containing only a few tons of ore to large, tabular masses containing many thousands of tons. The ore consists largely of sandstone selectively impregnated and in part replaced by uranium and vanadium minerals. Most of the deposits appear to be related to certain sedimentary structures in sandstones of favorable composition.

  4. Body build classification for ordinary schoolgirls (aged 7-18 years) and volleyball girls (aged 13-16 years).

    PubMed

    Kaarma, Helje; Stamm, Raini; Kasmel, Jaan; Koskel, Slide

    2005-03-01

    The article describes two Estonian anthropometric cross-sectional studies of 1549 ordinary schoolgirls (aged 7-18) and 46 girls, who regularly practised volleyball (aged 13-16). Data are presented on 22 basic anthropometric measurements and 6 body composition characteristics (body mass index, mean skinfold, body density, relative mass of fat by Siri, absolute mass and relative mass of subcutaneous adipose tissue). All anthropometric variables were classified into five height-weight SD classes. Schoolgirls were divided into six age groups (7-8, 9-10, 11-12, 13-14, 15-16, 17-18). Volleyballers were observed as one group as their age in SD classes did not differ significantly. The classification consisted of five categories: three height-weight concordant categories: I--small (small height, small weight), II--medium (medium height, medium weight), III large--(big height, big weight) and two height/weight discordant categories: IV--so-called pyknomorphs, V--so-called leptomorphs. To assess the differences between classes the Scheffé-test was used (alpha = 0.05). It proved likewise possible to comparatively systematize length, breadth and depth measurements, circumferences and body composition characteristics in all six age groups (7-18 years) of ordinary schoolgirls and in 13-16-year-old volleyballers as in their case the average age did not differ significantly between the classes.

  5. 117. 'THE MERRITT PARKWAY: CONNECTICUT'S ALLYEAR GATEWAY TO ENGLAND,' 1947 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    117. 'THE MERRITT PARKWAY: CONNECTICUT'S ALL-YEAR GATEWAY TO ENGLAND,' 1947 (RECTO). COLLECTION GEORGE L. LARNED. - Merritt Parkway, Beginning in Greenwich & running 38 miles to Stratford, Greenwich, Fairfield County, CT

  6. GATEWAY Demonstrations: Exploring SSL Product Performance in the Real World

    SciTech Connect

    2013-10-01

    Fact sheet that outlines DOE's GATEWAY technology demonstration program, which evaluates high-performance SSL products for general illumination in a variety of real-world exterior and interior applications.

  7. High-performance parallel interface to synchronous optical network gateway

    DOEpatents

    St. John, Wallace B.; DuBois, David H.

    1998-08-11

    A digital system provides sending and receiving gateways for HIPPI interfaces. Electronic logic circuitry formats data signals and overhead signals in a data frame that is suitable for transmission over a connecting fiber optic link. Multiplexers route the data and overhead signals to a framer module. The framer module allocates the data and overhead signals to a plurality of 9-byte words that are arranged in a selected protocol. The formatted words are stored in a storage register for output through the gateway.

  8. On Heterogeneous Mobile Network Connectivity: Number of Gateway Nodes

    DTIC Science & Technology

    2011-04-28

    clusters . Once the network has partitioned, mobile nodes cannot in different clusters cannot maintain connectivity due to insufficient radio...mobile nodes in different clusters can only occur when each cluster contains a gateway node. In this paper, we investigated the number of gateway...disperse geographical area. As tactical nodes move durng an operatioit. the network may partition into several segregated clusters . Once the network

  9. Effects of Age and Sex on the Development of Personal Space Schemata Towards Body Build

    ERIC Educational Resources Information Center

    Lerner, Richard M.; And Others

    1975-01-01

    This study assessed personal space schemata of children towards stimulus figures representing male and female body build stereotypes. Greater spatial distances were used towards the Endomorph than other physique types and significant sex differences were found. (GO)

  10. A Gateway MultiSite Recombination Cloning Toolkit

    PubMed Central

    Petersen, Lena K.; Stowers, R. Steven

    2011-01-01

    The generation of DNA constructs is often a rate-limiting step in conducting biological experiments. Recombination cloning of single DNA fragments using the Gateway system provided an advance over traditional restriction enzyme cloning due to increases in efficiency and reliability. Here we introduce a series of entry clones and a destination vector for use in two, three, and four fragment Gateway MultiSite recombination cloning whose advantages include increased flexibility and versatility. In contrast to Gateway single-fragment cloning approaches where variations are typically incorporated into model system-specific destination vectors, our Gateway MultiSite cloning strategy incorporates variations in easily generated entry clones that are model system-independent. In particular, we present entry clones containing insertions of GAL4, QF, UAS, QUAS, eGFP, and mCherry, among others, and demonstrate their in vivo functionality in Drosophila by using them to generate expression clones including GAL4 and QF drivers for various trp ion channel family members, UAS and QUAS excitatory and inhibitory light-gated ion channels, and QUAS red and green fluorescent synaptic vesicle markers. We thus establish a starter toolkit of modular Gateway MultiSite entry clones potentially adaptable to any model system. An inventory of entry clones and destination vectors for Gateway MultiSite cloning has also been established (www.gatewaymultisite.org). PMID:21931740

  11. "Gateway hypothesis" and early drug use: Additional findings from tracking a population-based sample of adolescents to adulthood.

    PubMed

    Nkansah-Amankra, Stephen; Minelli, Mark

    2016-12-01

    To evaluate the consistency of the relationship between early drug use in adolescence and illegal drug use in adulthood as proposed in the "gateway theory" and to determine whether pre-existing depressive symptoms modifies this relationship. We used contractual data from the National Longitudinal Study of Adolescent to Adult health data spanning a 14 year period. We assessed the relationship between gateway drugs at baseline (age 11-20 years) and drug use in adulthood using generalized estimating equation (GEE) regression models. Gateways drugs used in early adolescence were significantly associated with marijuana use, illegal drugs and cocaine in older adolescence, but over time these relationships were not consistent in adulthood. Changes in the pattern of psychoactive drug use were important predictors of drug use in adulthood. A history of higher depressive symptoms was associated with higher frequencies of psychoactive drug use over time. Users of mental health services in adolescence were less likely to use drugs in older adolescence and in adulthood. Relationships between early drug use and later drug use in adulthood cannot be solely explained by the gateway hypothesis. Collectively, adolescent drug prevention and treatment programs should apply theory-based and evidence-proven multisectoral intervention strategies rather than providing a brief counseling on individual's behaviors. This evidence should include understanding that changes in behavior should involve broader analyses of the underlying social context for drug use and in particular the role of the community social norms in driving a group's behaviors.

  12. A Life-course Perspective on the "Gateway Hypothesis".

    PubMed

    Van Gundy, Karen; Rebellon, Cesar J

    2010-09-01

    Drawing on stress and life-course perspectives and using panel data from 1,286 south Florida young adults, we assess three critical questions regarding the role of marijuana in the "gateway hypothesis." First, does teen marijuana use independently (causally) affect subsequent use of more dangerous substances? Second, if so, does that effect apply to the abuse of other illicit substances, as defined by the DSM-IV, or only to the use of such substances? Finally, does any causal effect of teen marijuana use survive beyond adolescence, or is it a short-term effect that subsides as adolescents transition to adulthood? Our results indicate a moderate relation between early teen marijuana use and young adult abuse of other illicit substances; however, this association fades from statistical significance with adjustments for stress and life-course variables. Likewise, our findings show that any causal influence of teen marijuana use on other illicit substance use is contingent upon employment status and is short-term, subsiding entirely by the age of 21. In light of these findings, we urge U.S. drug control policymakers to consider stress and life-course approaches in their pursuit of solutions to the "drug problem."

  13. EAARL topography: Gateway National Recreation Area

    USGS Publications Warehouse

    Brock, John C.; Wright, C. Wayne; Patterson, Matt; Nayegandhi, Amar; Patterson, Judd

    2007-01-01

    This Web site contains Lidar-derived topography (bare earth) maps and GIS files for the Sandy Hook Unit within Gateway National Recreation Area in New Jersey. These Lidar-derived topography maps were produced as a collaborative effort between the U.S. Geological Survey (USGS) Coastal and Marine Geology Program, FISC St. Petersburg, the National Park Service (NPS) South Florida/Caribbean Network Inventory and Monitoring Program, and the National Aeronautics and Space Administration (NASA) Wallops Flight Facility. One objective of this research is to create techniques to survey coral reefs and barrier islands for the purposes of geomorphic change studies, habitat mapping, ecological monitoring, change detection, and event assessment. As part of this project, data from an innovative instrument under development at the NASA Wallops Flight Facility, the NASA Experimental Airborne Advanced Research Lidar (EAARL) are being used. This sensor has the potential to make significant contributions in this realm for measuring subaerial and submarine topography wthin cross-environment surveys. High spectral resolution, water-column correction, and low costs were found to be key factors in providing accurate and affordable imagery to costal resource managers.

  14. E-Employment? College Grad Career Building in a Changing and Electronic Age

    ERIC Educational Resources Information Center

    Eisner, Susan

    2010-01-01

    The unusual nature of the current economic environment combined with changing labor market demographics heightens the importance to those engaged in employment activity of utilizing methods that fulfill their needs. But electronic technology is transforming available employment methods. How can career building and recruiting best be sustained in…

  15. Baby Minds: Brain-Building Games Your Baby Will Love. Birth to Age Three.

    ERIC Educational Resources Information Center

    Acredolo, Linda; Goodwyn, Susan

    Recent research points to the inborn abilities of infants and shows how early experiences influence cognitive skills. This book presents activities for parents and their infants--building on activities babies instinctively love--to develop their unique abilities. The book is organized around six intellectual skills: (1) problem solving; (2)…

  16. Accelerated ageing in testing bricks used in the conservation of historic buildings

    NASA Astrophysics Data System (ADS)

    Pavlendová, Gabriela; Podoba, Rudolf; Baník, Ivan

    2014-11-01

    The effect of accelerated climate ageing on historical bricks in the laboratory is investigated in the paper. Differences in thermal properties are experimentally determined and studied before and after bricks exposure to climate ageing, which consists of 60 freeze-thaw cycles. For measuring thermal conductivity, diffusivity and specific heat, pulse method is used.

  17. Building on Success: The Age of Energy Efficiency. Worldwatch Paper 82.

    ERIC Educational Resources Information Center

    Flavin, Christopher; Durning, Alan B.

    The post-World War II era is commonly described as the age of oil. Petroleum has fueled the industrialization process and has helped to raise living standards around the globe. At the same time, the current era has been referred to as the age of efficiency. Since 1973, it is estimated that the world saved far more energy through improved…

  18. Sensitivity of climate and Atlantic overturning circulation to uncertain ocean gateway configurations for the late Miocene

    NASA Astrophysics Data System (ADS)

    Bradshaw, C.; Lunt, D. J.; Flecker, R.; Martinez-Mendez, G.

    2013-12-01

    The palaeorecord documents late Miocene (11.6-5.3 Ma) climate to be much warmer and wetter than today yet CO2 reconstructions are similar to modern levels. Given the apparent decoupling between CO2 and warmth for this period we investigate here the role of the oceans. The late Miocene experienced significant tectonic change including the restriction of some of the last ocean gateways to close (Panama Gateway and Indonesian Seaway) and open (Bering Strait and Barents/Kara Sea). However, the timing and configuration of these tectonic changes is uncertain. The final closure of the Panama Gateway is dated to the Pliocene, but continental mammal exchange suggests the existence of a Central American archipelago from the mid-late Miocene. The Bering Strait is typically assumed to have opened at the very end of the late Miocene/early Pliocene based on diatom exchange, but other marine and terrestrial evidence points to a much earlier, perhaps intermittent, opening. The timing of the restriction of the Indonesian Seaway is very poorly constrained at middle Miocene to Pliocene. The Barents Sea and Kara Sea shelves are documented as having being subject to extensive glacial erosion and post-glacial uplift since the Pliocene and throughout the Quaternary but records of uplift and erosion during the earlier Cenozoic are limited. However, the presence of significant preglacial sediments suggests that this region underwent tectonic uplift, volcanism and subsequent erosion during the Eocene-Miocene period although the age assignment of the data remains controversial. The Panama Gateway has been suggested to influence North Atlantic Deep Water (NADW) production through numerous modelling studies, the Bering Strait has been suggested to greatly impact NADW during the Quaternary, and the strength of Indonesian Throughflow is hypothesised to influence Agulhas Leakage, which, in turn, has been speculated to influence Atlantic meridional overturning and thus NADW production. Here, we

  19. Using remotely-sensed multispectral imagery to build age models for alluvial fan surfaces

    NASA Astrophysics Data System (ADS)

    D'Arcy, Mitch; Mason, Philippa J.; Roda Boluda, Duna C.; Whittaker, Alexander C.; Lewis, James

    2016-04-01

    Accurate exposure age models are essential for much geomorphological field research, and generally depend on laboratory analyses such as radiocarbon, cosmogenic nuclide, or luminescence techniques. These approaches continue to revolutionise geomorphology, however they cannot be deployed remotely or in situ in the field. Therefore other methods are still needed for producing preliminary age models, performing relative dating of surfaces, or selecting sampling sites for the laboratory analyses above. With the widespread availability of detailed multispectral imagery, a promising approach is to use remotely-sensed data to discriminate surfaces with different ages. Here, we use new Landsat 8 Operational Land Imager (OLI) multispectral imagery to characterise the reflectance of 35 alluvial fan surfaces in the semi-arid Owens Valley, California. Alluvial fans are useful landforms to date, as they are widely used to study the effects of tectonics, climate and sediment transport processes on source-to-sink sedimentation. Our target fan surfaces have all been mapped in detail in the field, and have well-constrained exposure ages ranging from modern to ~ 125 ka measured using a high density of 10Be cosmogenic nuclide samples. Despite all having similar granitic compositions, the spectral properties of these surfaces vary systematically with their exposure ages. Older surfaces demonstrate a predictable shift in reflectance across the visible and short-wave infrared spectrum. Simple calculations, such as the brightness ratios of different wavelengths, generate sensitive power law relationships with exposure age that depend on post-depositional alteration processes affecting these surfaces. We investigate what these processes might be in this dryland location, and evaluate the potential for using remotely-sensed multispectral imagery for developing surface age models. The ability to remotely sense relative exposure ages has useful implications for preliminary mapping, selecting

  20. [Molecular mechanism for the establishment of blood-vessel gateway for immune cells in the CNS.

    PubMed

    Murakami, Masaaki

    2017-01-01

    We have been studying about the molecular mechanism responsible for the establishment of the blood-vessel gateway through which immune cells enter the CNS. We have discovered three kinds of gateways in a multiple sclerosis model, EAE, based on the neural stimulations and named them the gravity-gateway reflex, electric-gateway reflex, and pain-gateway reflex, respectively. All gateway reflexes are involved in specific crosstalk between sensory-sympathetic pathways. For example, in the gravity-gateway reflex, gravity-mediated sensory stimulation via the soleus muscles activates fifth lumber(L5)dorsal loot ganglions to activate L5 sympathetic ganglions, which express norepinephrine at specific vessels of the L5 cord. We explain these three types of gateway reflexes in this chapter.

  1. US Gateway to SIMBAD Astronomical Database

    NASA Technical Reports Server (NTRS)

    Eichhorn, G.

    1998-01-01

    During the last year the US SIMBAD Gateway Project continued to provide services like user registration to the US users of the SIMBAD database in France. User registration is required by the SIMBAD project in France. Currently, there are almost 3000 US users registered. We also provide user support by answering questions from users and handling requests for lost passwords. We have worked with the CDS SIMBAD project to provide access to the SIMBAD database to US users on an Internet address basis. This will allow most US users to access SIMBAD without having to enter passwords. This new system was installed in August, 1998. The SIMBAD mirror database at SAO is fully operational. We worked with the CDS to adapt it to our computer system. We implemented automatic updating procedures that update the database and password files daily. This mirror database provides much better access to the US astronomical community. We also supported a demonstration of the SIMBAD database at the meeting of the American Astronomical Society in January. We shipped computer equipment to the meeting and provided support for the demonstration activities at the SIMBAD booth. We continued to improve the cross-linking between the SIMBAD project and the Astro- physics Data System. This cross-linking between these systems is very much appreciated by the users of both the SIMBAD database and the ADS Abstract Service. The mirror of the SIMBAD database at SAO makes this connection faster for the US astronomers. The close cooperation between the CDS in Strasbourg and SAO, facilitated by this project, is an important part of the astronomy-wide digital library initiative called Urania. It has proven to be a model in how different data centers can collaborate and enhance the value of their products by linking with other data centers.

  2. US Gateway to SIMBAD Astronomical Database

    NASA Technical Reports Server (NTRS)

    Eichhorn, G.; Oliversen, R. (Technical Monitor)

    1999-01-01

    During the last year the US SIMBAD Gateway Project continued to provide services like user registration to the US users of the SIMBAD database in France. Currently there are over 3400 US users registered. We also provide user support by answering questions from users and handling requests for lost passwords when still necessary. We have implemented in cooperation with the CDS SIMBAD project access to the SIMBAD database for US users on an Internet address basis. This allows most US users to access SIMBAD without having to enter passwords. We have maintained the mirror copy of the SIMBAD database on a server at SAO. This has allowed much faster access for the US users. We also supported a demonstration of the SIMBAD database at the meeting of the American Astronomical Society in January. We shipped computer equipment to the meeting and provided support for the demonstration activities at the SIMBAD booth. We continued to improve the cross-linking between the SIMBAD project and the Astrophysics Data System. This cross-linking between these systems is very much appreciated by the users of both the SIMBAD database and the ADS Abstract Service. The mirror of the SIMBAD database at SAO makes this connection faster for the US astronomers. We exchange information between the ADS and SIMBAD on a daily basis. The close cooperation between the CDS in Strasbourg and SAO, facilitated by this project, is an important part of the astronomy-wide digital library initiative called Urania. It has proven to be a model in how different data centers can collaborate and enhance the value of their products by linking with other data centers.

  3. Data-intensive science gateway for rock physicists and volcanologists.

    NASA Astrophysics Data System (ADS)

    Filgueira, Rosa; Atkinson, Malcom; Bell, Andrew; Main, Ian; Boon, Steve; Meredith, Philp; Kilburn, Christopher

    2014-05-01

    Scientists have always shared data and mathematical models of the phenomena they study. Rock physics and Volcanology, as well as other solid-Earth sciences, have increasingly used Internet communications and computational renditions of their models for this purpose over the last two decades. Here we consider how to organise rock physics and volcanology data to open up opportunities for sharing and comparing both experiment data from experiments, observations and model runs and analytic interpretations of these data. Our hypothesis is that if we facilitate productive information sharing across those communities by using a new science gateway, it will benefit the science. The proposed science gateway should make the first steps for making existing research practices easier and facilitate new research. It will achieve this by supporting three major functions: 1) sharing data from laboratories and observatories, experimental facilities and models; 2) sharing models of rock fracture and methods for analysing experimental data; and 3) supporting recurrent operational tasks, such as data collection and model application in real time. We report initial work in two projects (NERC EFFORT and NERC CREEP-2) and experience with an early web-accessible protytpe called EFFORT gateway, where we are implementing such information sharing services for those projects. 1. Sharing data: In EFFORT gateway, we are working on several facilities for sharing data: *Upload data: We have designed and developed a new adaptive data transfer java tool called FAST (Flexible Automated Streaming Transfer) to upload experimental data and metadata periodically from laboratories to our repository. *Visualisation: As data are deposited in the repository, a visualisation of the accumulated data is made available for display in the Web portal. *Metadata and catalogues: The gateway uses a repository to hold all the data and a catalogue to hold all the corresponding metadata. 2. Sharing models and methods

  4. 78 FR 57371 - Agency Information Collection Activities; Comment Request; Student Aid Internet Gateway (SAIG...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-18

    ... Agency Information Collection Activities; Comment Request; Student Aid Internet Gateway (SAIG) Enrollment... notice will be considered public records. Title of Collection: Student Aid Internet Gateway (SAIG...: Enrollment in the Federal Student Aid (FSA) Student Aid Internet Gateway (SAIG) allows eligible entities...

  5. Alcohol as a Gateway Drug: A Study of US 12th Graders

    ERIC Educational Resources Information Center

    Kirby, Tristan; Barry, Adam E.

    2012-01-01

    Background: The Gateway Drug Theory suggests that licit drugs, such as tobacco and alcohol, serve as a "gateway" toward the use of other, illicit drugs. However, there remains some discrepancy regarding which drug--alcohol, tobacco, or even marijuana--serves as the initial "gateway" drug subsequently leading to the use of…

  6. Flooding and subsidence in the Thames Gateway: impact on insurance loss potential

    NASA Astrophysics Data System (ADS)

    Royse, Katherine; Horn, Diane; Eldridge, Jillian; Barker, Karen

    2010-05-01

    In the UK, household buildings insurance generally covers loss and damage to the insured property from a range of natural and human perils, including windstorm, flood, subsidence, theft, accidental fire and winter freeze. Consequently, insurers require a reasoned view on the likely scale of losses that they may face to assist in strategic planning, reinsurance structuring, regulatory returns and general risk management. The UK summer 2007 flood events not only provided a clear indication of the scale of potential losses that the industry could face from an individual event, with £3 billion in claims, but also identified a need for insurers and reinsurers to better understand how events may correlate in time and space, and how to most effectively use the computational models of extreme events that are commonly applied to reflect these correlations. In addition to the potential for temporal clustering of events such as windstorms and floods, there is a possibility that seemingly uncorrelated natural perils, such as floods and subsidence, may impact an insurer's portfolio. Where aggregations of large numbers of new properties are planned, such as in the Thames Gateway, consideration of the potential future risk of aggregate losses due to the combination of perils such as subsidence and flood is increasingly important within the insurance company's strategic risk management process. Whilst perils such as subsidence and flooding are generally considered independent within risk modelling, the potential for one event to influence the magnitude and likelihood of the other should be taken into account when determining risk level. In addition, the impact of correlated, but distinctive, loss causing events on particular property types may be significant, particularly if a specific property is designed to protect against one peril but is potentially susceptible to another. We suggest that flood events can lead to increased subsidence risk due to the weight of additional water

  7. The Importance of Social Connectedness in Building Age-Friendly Communities

    PubMed Central

    Emlet, Charles A.; Moceri, Joane T.

    2012-01-01

    The purpose of this paper is to further elucidate the importance of social relationships and social connectedness with aging in place and in developing elder-friendly communities. The process used in this study was inclusive of younger adults (age 40–65) as well as older adults (65+) in order to further understand how they envision a community that could support their own aging in place. A community forum, using the World Café format, was conducted in order to engage community members, 40 years and older, in conversation about the importance of social connectedness in elder-friendly communities. A second purpose of this forum was to obtain data on what would keep aging boomers in their community as they age. Three major themes emerged from qualitative analysis of the forum: social reciprocity, meaningful interactions, and structural needs/barriers. The results of this study reinforce the importance of social connectedness in creating and maintaining elder-friendly communities for older adults, as well as soon-to-be retired individuals, wishing to maintain life connectedness to their community. The study suggests the possibility of using more nontraditional research techniques (such as the World Café process) for gathering community level data. PMID:22162807

  8. The importance of social connectedness in building age-friendly communities.

    PubMed

    Emlet, Charles A; Moceri, Joane T

    2012-01-01

    The purpose of this paper is to further elucidate the importance of social relationships and social connectedness with aging in place and in developing elder-friendly communities. The process used in this study was inclusive of younger adults (age 40-65) as well as older adults (65+) in order to further understand how they envision a community that could support their own aging in place. A community forum, using the World Café format, was conducted in order to engage community members, 40 years and older, in conversation about the importance of social connectedness in elder-friendly communities. A second purpose of this forum was to obtain data on what would keep aging boomers in their community as they age. Three major themes emerged from qualitative analysis of the forum: social reciprocity, meaningful interactions, and structural needs/barriers. The results of this study reinforce the importance of social connectedness in creating and maintaining elder-friendly communities for older adults, as well as soon-to-be retired individuals, wishing to maintain life connectedness to their community. The study suggests the possibility of using more nontraditional research techniques (such as the World Café process) for gathering community level data.

  9. The IPY Arctic Gateway at the University Centre in Svalbard (UNIS) at 78°N

    NASA Astrophysics Data System (ADS)

    Behlke, R.; Markusson, E.; Christiansen, H.; Skancke Hansen, F.

    2007-12-01

    An important part of the International Polar Year (IPY) is to provide information about the IPY to researchers, the local community, media, tourists and the general public. In order to serve this purpose, an IPY Educational and Outreach Centre has been established at the University Centre in Svalbard (UNIS) which is located at 78°N. The Gateway is situated in a 70 square meter locality within the Svalbard Science Centre (SSC). It provides access to six computers with internet access as well as printing and faxing facilities. In addition, both poster and screen presentations on IPY projects active on Svalbard can be viewed. Reading material (booklets and brochures) is also available. This presentation gives an overview of the activities of the Gateway during the first months of operation and future work. This includes (1) establishing a physical contact point in the Arctic for relevant inquires from media and other interested, (2) providing a service to field researchers visiting Svalbard during the IPY, (3) supporting local capacity building by informing the local community about research related questions, (4) exploring the possibilities of setting up a program for teachers from primary and secondary schools to engage in field research on Svalbard, (5) helping to faciliate science based tourism in cooperation with local tourist operators, (6) establishing the SSC as the hub for education and research on Svalbard.

  10. Promoting healthy, meaningful aging through social involvement: building an experience corps.

    PubMed

    Carlson, Michelle C

    2011-05-01

    Pathways responsible for higher-order thinking in the prefrontal cortex (PFC), or executive center of the brain, remain vulnerable throughout life-during critical early-life developmental windows, when the PFC fully matures in the early 20s, and finally from declines associated with old age. At all ages, physical activity and PFC-navigated social connections are essential components to maintaining brain health. The Experience Corps, a community-based social-engagement program, partners seniors with local schools to promote purpose-driven involvement. Participating seniors have exhibited immediate short-term gains in brain regions vulnerable to aging, such as the PFC, indicating that people with the most to lose have the most to gain from environmental enrichment.

  11. Efficient preparation of shuffled DNA libraries through recombination (Gateway) cloning.

    PubMed

    Lehtonen, Soili I; Taskinen, Barbara; Ojala, Elina; Kukkurainen, Sampo; Rahikainen, Rolle; Riihimäki, Tiina A; Laitinen, Olli H; Kulomaa, Markku S; Hytönen, Vesa P

    2015-01-01

    Efficient and robust subcloning is essential for the construction of high-diversity DNA libraries in the field of directed evolution. We have developed a more efficient method for the subcloning of DNA-shuffled libraries by employing recombination cloning (Gateway). The Gateway cloning procedure was performed directly after the gene reassembly reaction, without additional purification and amplification steps, thus simplifying the conventional DNA shuffling protocols. Recombination-based cloning, directly from the heterologous reassembly reaction, conserved the high quality of the library and reduced the time required for the library construction. The described method is generally compatible for the construction of DNA-shuffled gene libraries.

  12. BODY IMAGE AMONG MEN WHO PRACTICE BODY BUILDING: COMPARISON BY AGE, ECONOMIC STATUS, AND CITY SIZE.

    PubMed

    Silva, Diego A S; Da Silva, Rafael C; Gonçalves, Eliane C A

    2015-10-01

    Identifying the factors that influence the body image of body builders is important for understanding this construct. The aim of this study was to analyze the association between body image and age, socioeconomic status, and place of residence of body builders from two cities in Brazil. A cross-sectional study of 301 body builders with an average age of 25.2 yr. (SD = 3.5) was carried out. The Muscle Silhouette Measure scale was used, in which the discrepancy between current and desired silhouette was examined. Older body builders showed greater discrepancy between current and desired silhouette, reflecting their desire for a more muscular body.

  13. Ecstasy and Gateway Drugs: Initiating the Use of Ecstasy and Other Drugs

    PubMed Central

    Reid, Lesley W.; Elifson, Kirk W.; Sterk, Claire E.

    2007-01-01

    Purpose The main purposes of this study are to examine if, and to what extent, ecstasy use serves as a gateway to the use of hard drugs such as cocaine, heroin, and methamphetamine and to compare the age of onset of alcohol and marijuana use and subsequent use of cocaine, heroin, and methamphetamine among young adult ecstasy users. Methods Face-to-face surveys were conducted with 268 young adult ecstasy users in Atlanta, Georgia. Subjects were solicited using the community identification process, including targeted sampling and guided recruitment. Data analysis involved discrete-time, event history analysis. Results Results suggest that the age of onset of ecstasy use influences the initiation of cocaine and methamphetamine for our sample of active ecstasy users. In addition, alcohol and marijuana use precedes the initiation of cocaine and methamphetamine, but only marijuana influences the initiation of heroin. Conclusions The sequential progression of drug use proposed in the gateway literature is not immutable. Researchers must take into account the changing popularity of drugs over time, such as the emergence of ecstasy use, when identifying patterns of drug use onset. PMID:17140814

  14. Signatures of mountain building: Detrital zircon U/Pb ages from northeast Tibet

    USGS Publications Warehouse

    Lease, Richard O.; Burbank, Douglas W.; Gehrels, George E.; Wang, Zhicai; Yuan, Daoyang

    2007-01-01

    Although detrital zircon has proven to be a powerful tool for determining provenance, past work has focused primarily on delimiting regional source terranes. Here we explore the limits of spatial resolution and stratigraphic sensitivity of detrital zircon in ascertaining provenance, and we demonstrate its ability to detect source changes for terranes separated by only a few tens of kilometers. For such an analysis to succeed for a given mountain, discrete intrarange source terranes must have unique U/Pb zircon age signatures and sediments eroded from the range must have well-defined depositional ages. Here we use ∼1400 single-grain U/Pb zircon ages from northeastern Tibet to identify and analyze an area that satisfies these conditions. This analysis shows that the edges of intermontane basins are stratigraphically sensitive to discrete, punctuated changes in local source terranes. By tracking eroding rock units chronologically through the stratigraphic record, this sensitivity permits the detection of the differential rock uplift and progressive erosion that began ca. 8 Ma in the Laji Shan, a 10-25-km-wide range in northeastern Tibet with a unique U/Pb age signature.

  15. Building an integrated research/policy planning age-friendly agenda.

    PubMed

    Glicksman, Allen; Clark, Kate; Kleban, Morton H; Ring, Lauren; Hoffman, Christine

    2014-01-01

    This article describes an innovative model for integrating research into a policy and planning agenda aimed to help neighborhoods become more supportive of older adults. Philadelphia Corporation for Aging (PCA) established Age-Friendly Philadelphia (AFP) to catalyze efforts to improve the physical and social environments for seniors. The Research Program at PCA became an important part of this effort by providing multiple types of supports to PCA staff and other stakeholders. Most notably, the research program worked with planners to adopt the United States Environmental Protection Agency's Aging Initiative model for Philadelphia. That model focuses on (1) staying active, connected, and engaged; (2) development and housing; (3) transportation and mobility; and (4) staying healthy. Examples of practice efforts actualized using this research are also presented. By developing a new approach to the way research can support practice initiatives, AFP has been able to increase its effectiveness, and researchers have found better ways to work collaboratively with professionals in policy, planning, and practice. The PCA model should be considered as a framework for similar efforts aimed at creating age-friendly communities.

  16. BUILDING REALISTIC BIOLOGICALLY-BASED PHARMACOKINETIC MODELS FOR PREDICTING SUSCEPTIBILITY IN THE AGED POPULATIONS

    EPA Science Inventory

    Detoxification and elimination of xenobiotics is a major function of the liver and is important in maintaining the metabolic homeostasis of the organism. The degree to which aging affects hepatic metabolism is not known. The expression of XMEs, in part, determines the fate of the...

  17. Building Self-Esteem in Boys of Elementary School Age from Alcoholic Families.

    ERIC Educational Resources Information Center

    Hess, Cheryl L.

    Alcoholism is a growing problem in America today. Children are becoming addicted to chemicals at a much younger age. Those children who have alcoholic parents and/or grandparents are more susceptible to addiction because of hereditary factors. Children of alcoholic parents live amidst conflict and confusion. Because of this conflict and confusion,…

  18. Building a Method for Researching Attribution of Meaning by Children Aged 5 to 6 in School

    ERIC Educational Resources Information Center

    Tertoolen, Anja; van Oers, Bert; Geldens, Jeannette; Popeijus, Herman

    2012-01-01

    This article reports on the first phase of a research project in which we looked for the voices of young children, aged 5 to 6, in school. What do children experience in school? What do they see as the meaning of school? What is their motivation? Children have the right to be listened to. The question is which settings, under which circumstances,…

  19. Catching the Age Wave: Building Schools with Senior Citizens in Mind.

    ERIC Educational Resources Information Center

    Sullivan, Kevin J.

    Examining the trend toward an older U.S. population, this paper discusses why educators and school facility planners should consider designing multipurpose schools that specifically contribute to stronger intergenerational links. Reasons include: ending age segregation, enriching the lives of children and seniors, creating support for public…

  20. WorldWideScience.org: the global science gateway.

    PubMed

    Fitzpatrick, Roberta Bronson

    2009-10-01

    WorldWideScience.org is a Web-based global gateway connecting users to both national and international scientific databases and portals. This column will provide background information on the resource as well as introduce basic searching practices for users.

  1. 47 CFR 10.320 - Provider alert gateway requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Section 10.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM... file into the format supported by mobile devices. (2) Reception. The CMS provider gateway must support... that each Participating Commercial Mobile Service provider is required to support and perform at...

  2. 47 CFR 10.320 - Provider alert gateway requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... file into the format supported by mobile devices. (2) Reception. The CMS provider gateway must support... Section 10.320 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMERCIAL MOBILE ALERT SYSTEM... that each Participating Commercial Mobile Service provider is required to support and perform at...

  3. Quality-controlled Subject Gateways: Definitions, Typologies, Empirical Overview.

    ERIC Educational Resources Information Center

    Koch, Traugott

    2000-01-01

    "Quality-controlled subject gateways" are Internet services which apply quality measures to support systematic resource discovery. A main goal is to provide high quality subject access through indexing resources using controlled vocabularies and by offering a deep classification structure for advanced searching and browsing. Provides an…

  4. Shield Optimization in Simple Geometry for the Gateway Concept

    NASA Technical Reports Server (NTRS)

    Tripathi, R. K.; Simonsen, L. C.; Nealy, J. E.; Troutman, P. A.; Wilson, J. W.

    2002-01-01

    The great cost of added radiation shielding is a potential limiting factor in many deep space missions. For this enabling technology, we are developing tools for optimized shield design over multi-segmented missions involving multiple work and living areas in the transport and duty phase of various space missions. The total shield mass over all pieces of equipment and habitats is optimized subject to career dose and dose rate constraints. Preliminary studies of deep space missions indicate that for long duration space missions, improved shield materials will be required. The details of this new method and its impact on space missions and other technologies will be discussed. This study will provide a vital tool for evaluating Gateway designs in their usage context. Providing protection against the hazards of space radiation is one of the challenges to the Gateway infrastructure designs. We will use the mission optimization software to scope the impact of Gateway operations on human exposures and the effectiveness of alternate shielding materials on Gateway infrastructure designs. This study will provide a guide to the effectiveness of multifunctional materials in preparation to more detailed geometry studies in progress.

  5. GATEWAYS Music Curriculum for Musically Talented Children. Report #367.

    ERIC Educational Resources Information Center

    Spencer, Melody, Ed.; Hersh, Leonard R., Ed.

    Designed to challenge the special abilities of musically talented and gifted elementary level students, this Gateways music curriculum guide presents enrichment programs that enhance, rather than supplant, the regular music program. Part 1 describes this program's philosophy, which is based upon Joseph Renzulli's Enrichment Triad Model which…

  6. Preliminary Economic Analysis of the Ozark Gateway District.

    ERIC Educational Resources Information Center

    Economic Research Service (USDA), Washington, DC.

    Thirty-nine tables on the economic and social trends from 1950-67 in the Ozark Gateway District are presented in this report. This four-county area in Southwest Missouri was dormant for over 10 years, with limited population growth, low levels of productivity, and low incomes. It was operating below its potential level of general business activity…

  7. Tobacco, the Common Enemy and a Gateway Drug: Policy Implications

    ERIC Educational Resources Information Center

    Torabi, Mohammad R.; Jun, Mi Kyung; Nowicke, Carole; Seitz de Martinez, Barbara; Gassman, Ruth

    2010-01-01

    For the four leading causes of death in the United States (heart disease, cancer, stroke and chronic respiratory disease), tobacco use is a common risk factor. Tobacco use is responsible for almost 450,000 deaths per year and impacts the health of every member of our society. Tobacco is a gateway drug for substance abuse. That role is critical to…

  8. A Life-Course Perspective on the "Gateway Hypothesis"

    ERIC Educational Resources Information Center

    Van Gundy, Karen; Rebellon, Cesar J.

    2010-01-01

    Drawing on stress and life-course perspectives and using panel data from 1,286 south Florida young adults, we assess three critical questions regarding the role of marijuana in the "gateway hypothesis." First, does teen marijuana use independently (causally) affect subsequent use of more dangerous substances? Second, if so, does that…

  9. Assessment and Placement: Supporting Student Success in College Gateway Courses

    ERIC Educational Resources Information Center

    Vandal, Bruce

    2014-01-01

    Evidence is mounting that the vast majority of students who are currently placed into prerequisite remedial education could be successful in gateway college-­level courses if they receive additional academic support as a corequisite. Recent research on college placement exams reveals that the exams are unreliable at predicting college success, and…

  10. Optimization Shield Materials Trade Study for Lunar/Gateway Mission

    NASA Technical Reports Server (NTRS)

    Tripathi, R. K.; Wilson, J. W.; Cucinotta, F. A.; Anderson, B. M.; Simonsen, L. C.

    2002-01-01

    The great cost of added radiation shielding is a potential limiting factor in many deep space missions. For this enabling technology, we are developing tools for optimized shield design over multi-segmented missions involving multiple work and living areas in the transport and duty phase of various space missions. The total shield mass over all pieces of equipment and habitats is optimized subject to career dose and dose rate constraints. Preliminary studies of deep space missions indicate that for long duration space missions, improved shield materials will be required. The details of this new method and its impact on space missions and other technologies will be discussed. This study will provide a vital tool for evaluating Gateway designs in their usage context. Providing protection against the hazards of space radiation is one of the challenges to the Gateway infrastructure designs. We will use the mission optimization software to scope the impact of Gateway operations on human exposures and the effectiveness of alternate shielding materials on Gateway infrastructure designs. It is being proposed to use Moon and the Lagrange points as the hub for deep space missions. This study will provide a guide to the effectiveness of multifunctional materials in preparation to more detailed geometry studies in progress.

  11. The Vocational Baccalaureate: A Gateway to Higher Education?

    ERIC Educational Resources Information Center

    Gendron, Benedicte

    2009-01-01

    Access to the baccalaureate and higher education in France has become more democratic. The introduction of the vocational baccalaureate has been part of this process, but remains a modest step forward given the very low take-up of vocational baccalaureate courses. If vocational education pathways in France are to become true gateways to higher…

  12. Thermoclastic and cryoclastic action on calcareous building stone: durability to artificial ageing

    NASA Astrophysics Data System (ADS)

    Germinario, Luigi; Andriani, Gioacchino Francesco; Laviano, Rocco

    2014-05-01

    Short and long-term climate changes are a critical factor of stone decay even in temperate Mediterranean areas, when the combined fluctuations of temperature and moisture lead to thermoclastism and cryoclastism. The effects of weathering are of particular concern in the conservation field, for the assessment of the vulnerability of outdoor-exposed stone materials in the historical built heritage. An example of this outline is Apulia, a region of southern Italy characterized by warm, dry summers and mild, rather rainy winters that can bring sub-zero temperatures; here, climate-driven decay can seriously affect the state of conservation of the local calcareous stone used in the monumental heritage, especially the most porous and softest materials. The dynamic behavior of the Apulian calcareous stone in response to thermo-hygrometric stresses was studied here by means of an artificial accelerated ageing test, focusing on a single local stone variety known as "pietra gentile". It is a fine-grained, soft and porous calcarenite, which is exploited in the Murge area from the outcrops of the "Calcare di Caranna" Fm. (late Campanian?-Maastrichtian). The quarrying activity is concentrated in the territory of Valle d'Itria and mainly of Ostuni, touristically known as "the White Town", where the stone is widely used for the sacred and civil architecture. The ageing test was programmed according to the typical climatic characteristics of the considered area, following the historical recordings by the official Apulian monitoring institute (Struttura di Monitoraggio Meteoclimatico, Centro Funzionale Regionale); in order to simulate the seasonal climatic changes, the extreme temperatures were considered, while the possible insolation effects for higher temperatures were also taken into account. So, samples of "pietra gentile" were subjected to 100 temperature cycles from 60 to -5 °C, in a climatic chamber with a maximum relative humidity of 60%. Before the ageing, the samples

  13. STEM Education as a Gateway to Future Astronomy: the Case of Ethiopian Universities

    NASA Astrophysics Data System (ADS)

    Adhana Teklr, Kelali

    2015-08-01

    Over last two decades education sector in Ethiopia has got due attention. To meet the education deficit of the nation number of universities has been increased from two to thirty eight and twelve more are coming soon. The proliferation has brought a spillover effect that universities have to compete for center excellence in research and education. Convincingly, government’s support is geared towards knowledge-based and innovation-driven system of education to back up the green economic development plan.In an effort to build inclusive economic development emphasis is given to innovative competency building through science and technology fields. The universities in the nation have establish laboratories to educate school boys and girls at early stage of their schooling in STEM (Science, Technology, Engineering and Mathematics) subjects as means to paving future destiny. Though most of the astronomy and space science labs are virtual ones; more and more student have been inspired and want astronomy and space science as their future career fields. Assessment study carried out in universities running STEM education showed that there is a mismatch between the capacity of the labs and number of students wanted to study astronomy and space sciences. The universities have endorsed that STEM education is the gateway to future astronomy and strongly advised concerned bodies and partnering institutions to collaboratively work to intensify the teaching-learning of STEM subjects.The assessment study compiled astronomic and space science exercises carried out by instructors and students and the document is ready to be disseminated to universities and middle and secondary schools to promote the science nationwide. The results have motivated university instructors, science and technology professionals, researchers and policy makers to be more involved in shaping future destiny of the young generation and have their shown determination to support the STEM education so that it will

  14. Building Bridges for Innovation in Ageing: Synergies between Action Groups of the EIP on AHA.

    PubMed

    Bousquet, J; Bewick, M; Cano, A; Eklund, P; Fico, G; Goswami, N; Guldemond, N A; Henderson, D; Hinkema, M J; Liotta, G; Mair, A; Molloy, W; Monaco, A; Monsonis-Paya, I; Nizinska, A; Papadopoulos, H; Pavlickova, A; Pecorelli, S; Prados-Torres, A; Roller-Wirnsberger, R E; Somekh, D; Vera-Muñoz, C; Visser, F; Farrell, J; Malva, J; Andersen Ranberg, K; Camuzat, T; Carriazo, A M; Crooks, G; Gutter, Z; Iaccarino, G; Manuel de Keenoy, E; Moda, G; Rodriguez-Mañas, L; Vontetsianos, T; Abreu, C; Alonso, J; Alonso-Bouzon, C; Ankri, J; Arredondo, M T; Avolio, F; Bedbrook, A; Białoszewski, A Z; Blain, H; Bourret, R; Cabrera-Umpierrez, M F; Catala, A; O'Caoimh, R; Cesari, M; Chavannes, N H; Correia-da-Sousa, J; Dedeu, T; Ferrando, M; Ferri, M; Fokkens, W J; Garcia-Lizana, F; Guérin, O; Hellings, P W; Haahtela, T; Illario, M; Inzerilli, M C; Lodrup Carlsen, K C; Kardas, P; Keil, T; Maggio, M; Mendez-Zorrilla, A; Menditto, E; Mercier, J; Michel, J P; Murray, R; Nogues, M; O'Byrne-Maguire, I; Pappa, D; Parent, A S; Pastorino, M; Robalo-Cordeiro, C; Samolinski, B; Siciliano, P; Teixeira, A M; Tsartara, S I; Valiulis, A; Vandenplas, O; Vasankari, T; Vellas, B; Vollenbroek-Hutten, M; Wickman, M; Yorgancioglu, A; Zuberbier, T; Barbagallo, M; Canonica, G W; Klimek, L; Maggi, S; Aberer, W; Akdis, C; Adcock, I M; Agache, I; Albera, C; Alonso-Trujillo, F; Angel Guarcia, M; Annesi-Maesano, I; Apostolo, J; Arshad, S H; Attalin, V; Avignon, A; Bachert, C; Baroni, I; Bel, E; Benson, M; Bescos, C; Blasi, F; Barbara, C; Bergmann, K C; Bernard, P L; Bonini, S; Bousquet, P J; Branchini, B; Brightling, C E; Bruguière, V; Bunu, C; Bush, A; Caimmi, D P; Calderon, M A; Canovas, G; Cardona, V; Carlsen, K H; Cesario, A; Chkhartishvili, E; Chiron, R; Chivato, T; Chung, K F; d'Angelantonio, M; De Carlo, G; Cholley, D; Chorin, F; Combe, B; Compas, B; Costa, D J; Costa, E; Coste, O; Coupet, A-L; Crepaldi, G; Custovic, A; Dahl, R; Dahlen, S E; Demoly, P; Devillier, P; Didier, A; Dinh-Xuan, A T; Djukanovic, R; Dokic, D; Du Toit, G; Dubakiene, R; Dupeyron, A; Emuzyte, R; Fiocchi, A; Wagner, A; Fletcher, M; Fonseca, J; Fougère, B; Gamkrelidze, A; Garces, G; Garcia-Aymeric, J; Garcia-Zapirain, B; Gemicioğlu, B; Gouder, C; Hellquist-Dahl, B; Hermosilla-Gimeno, I; Héve, D; Holland, C; Humbert, M; Hyland, M; Johnston, S L; Just, J; Jutel, M; Kaidashev, I P; Khaitov, M; Kalayci, O; Kalyoncu, A F; Keijser, W; Kerstjens, H; Knezović, J; Kowalski, M; Koppelman, G H; Kotska, T; Kovac, M; Kull, I; Kuna, P; Kvedariene, V; Lepore, V; MacNee, W; Maggio, M; Magnan, A; Majer, I; Manning, P; Marcucci, M; Marti, T; Masoli, M; Melen, E; Miculinic, N; Mihaltan, F; Milenkovic, B; Millot-Keurinck, J; Mlinarić, H; Momas, I; Montefort, S; Morais-Almeida, M; Moreno-Casbas, T; Mösges, R; Mullol, J; Nadif, R; Nalin, M; Navarro-Pardo, E; Nekam, K; Ninot, G; Paccard, D; Pais, S; Palummeri, E; Panzner, P; Papadopoulos, N K; Papanikolaou, C; Passalacqua, G; Pastor, E; Perrot, M; Plavec, D; Popov, T A; Postma, D S; Price, D; Raffort, N; Reuzeau, J C; Robine, J M; Rodenas, F; Robusto, F; Roche, N; Romano, A; Romano, V; Rosado-Pinto, J; Roubille, F; Ruiz, F; Ryan, D; Salcedo, T; Schmid-Grendelmeier, P; Schulz, H; Schunemann, H J; Serrano, E; Sheikh, A; Shields, M; Siafakas, N; Scichilone, N; Siciliano, P; Skrindo, I; Smit, H A; Sourdet, S; Sousa-Costa, E; Spranger, O; Sooronbaev, T; Sruk, V; Sterk, P J; Todo-Bom, A; Touchon, J; Tramontano, D; Triggiani, M; Tsartara, S I; Valero, A L; Valovirta, E; van Ganse, E; van Hage, M; van den Berge, M; Vandenplas, O; Ventura, M T; Vergara, I; Vezzani, G; Vidal, D; Viegi, G; Wagemann, M; Whalley, B; Wickman, M; Wilson, N; Yiallouros, P K; Žagar, M; Zaidi, A; Zidarn, M; Hoogerwerf, E J; Usero, J; Zuffada, R; Senn, A; de Oliveira-Alves, B

    2017-01-01

    The Strategic Implementation Plan of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) proposed six Action Groups. After almost three years of activity, many achievements have been obtained through commitments or collaborative work of the Action Groups. However, they have often worked in silos and, consequently, synergies between Action Groups have been proposed to strengthen the triple win of the EIP on AHA. The paper presents the methodology and current status of the Task Force on EIP on AHA synergies. Synergies are in line with the Action Groups' new Renovated Action Plan (2016-2018) to ensure that their future objectives are coherent and fully connected. The outcomes and impact of synergies are using the Monitoring and Assessment Framework for the EIP on AHA (MAFEIP). Eight proposals for synergies have been approved by the Task Force: Five cross-cutting synergies which can be used for all current and future synergies as they consider overarching domains (appropriate polypharmacy, citizen empowerment, teaching and coaching on AHA, deployment of synergies to EU regions, Responsible Research and Innovation), and three cross-cutting synergies focussing on current Action Group activities (falls, frailty, integrated care and chronic respiratory diseases).

  15. The impact of Southern Ocean gateways on the Cenozoic climate evolution

    NASA Astrophysics Data System (ADS)

    von der Heydt, Anna; Viebahn, Jan; Dijkstra, Henk

    2016-04-01

    During the Cenozoic period, which covers the last 65 Million (Ma) years, Earth's climate has undergone a major long-term transition from warm "greenhouse" to colder "icehouse" conditions with extensive ice sheets in the polar regions of both hemispheres. On the very long term the gradual cooling may be seen as response to the overall slowly decreasing atmospheric CO2-concentration due to weathering processes in the Earth System, however, continental geometry has changed considerably over this period and the long-term gradual trend was interrupted, by several rapid transitions as well as periods where temperature and greenhouse gas concentrations seem to be decoupled. The Eocene-Oligocene boundary (˜34 Ma, E/O) and mid-Miocene climatic transition (˜13 Ma, MCT) reflect major phases of Antarctic ice sheet build-up and global climate cooling, while Northern Hemisphere ice sheets developed much later, most likely at the Pliocene-Pleistocene transition (˜2.7Ma). Thresholds in atmospheric CO2-concentration together with feedback mechanisms related to land ice formation are now among the favoured mechanisms of these climatic transitions, while the long-proposed ocean circulation changes caused by opening of tectonic gateways seem to play a less direct role. The opening of the Southern Ocean gateways, notably the Drake Passage and the Tasman Gateway as well as the northward movement of Australia over this long time period, however, has eventually led to the development of today's strongest ocean current, the Antarctic Circumpolar Current (ACC), playing a major role in the transport properties of the global ocean circulation. The overall state of the global ocean circulation, therefore, preconditions the climate system to dramatic events such as major ice sheet formation. Here, we present results of a state-of-the art global climate model (CESM) under various continental configurations: (i) present day geometry, (ii) present day geometry with a closed Drake Passage and

  16. Urban Gateways Arts for Learning Program. Chapter 1 ECIA Selection, 1983-1984. [and] Urban Gateways Artist-in-Residence Programs.

    ERIC Educational Resources Information Center

    Urbana Gateways, Chicago, IL.

    Two documents are combined. The first describes the Arts for Learning program provided by Urban Gateways, a Chicago-based, nonprofit arts and education organization that serves as a resource for schools in six Illinois counties. Urban Gateways provides the resources to make the arts an integral part of the learning process in elementary and…

  17. Eocene cooling linked to early flow across the Tasmanian Gateway.

    PubMed

    Bijl, Peter K; Bendle, James A P; Bohaty, Steven M; Pross, Jörg; Schouten, Stefan; Tauxe, Lisa; Stickley, Catherine E; McKay, Robert M; Röhl, Ursula; Olney, Matthew; Sluijs, Appy; Escutia, Carlota; Brinkhuis, Henk

    2013-06-11

    The warmest global temperatures of the past 85 million years occurred during a prolonged greenhouse episode known as the Early Eocene Climatic Optimum (52-50 Ma). The Early Eocene Climatic Optimum terminated with a long-term cooling trend that culminated in continental-scale glaciation of Antarctica from 34 Ma onward. Whereas early studies attributed the Eocene transition from greenhouse to icehouse climates to the tectonic opening of Southern Ocean gateways, more recent investigations invoked a dominant role of declining atmospheric greenhouse gas concentrations (e.g., CO2). However, the scarcity of field data has prevented empirical evaluation of these hypotheses. We present marine microfossil and organic geochemical records spanning the early-to-middle Eocene transition from the Wilkes Land Margin, East Antarctica. Dinoflagellate biogeography and sea surface temperature paleothermometry reveal that the earliest throughflow of a westbound Antarctic Counter Current began ~49-50 Ma through a southern opening of the Tasmanian Gateway. This early opening occurs in conjunction with the simultaneous onset of regional surface water and continental cooling (2-4 °C), evidenced by biomarker- and pollen-based paleothermometry. We interpret that the westbound flowing current flow across the Tasmanian Gateway resulted in cooling of Antarctic surface waters and coasts, which was conveyed to global intermediate waters through invigorated deep convection in southern high latitudes. Although atmospheric CO2 forcing alone would provide a more uniform middle Eocene cooling, the opening of the Tasmanian Gateway better explains Southern Ocean surface water and global deep ocean cooling in the apparent absence of (sub-) equatorial cooling.

  18. Eocene cooling linked to early flow across the Tasmanian Gateway

    PubMed Central

    Bijl, Peter K.; Bendle, James A. P.; Bohaty, Steven M.; Pross, Jörg; Schouten, Stefan; Tauxe, Lisa; Stickley, Catherine E.; McKay, Robert M.; Röhl, Ursula; Olney, Matthew; Sluijs, Appy; Escutia, Carlota; Brinkhuis, Henk; Klaus, Adam; Fehr, Annick; Williams, Trevor; Carr, Stephanie A.; Dunbar, Robert B.; Gonzàlez, Jhon J.; Hayden, Travis G.; Iwai, Masao; Jimenez-Espejo, Francisco J.; Katsuki, Kota; Kong, Gee Soo; Nakai, Mutsumi; Passchier, Sandra; Pekar, Stephen F.; Riesselman, Christina; Sakai, Toyosaburo; Shrivastava, Prakash K.; Sugisaki, Saiko; Tuo, Shouting; van de Flierdt, Tina; Welsh, Kevin; Yamane, Masako

    2013-01-01

    The warmest global temperatures of the past 85 million years occurred during a prolonged greenhouse episode known as the Early Eocene Climatic Optimum (52–50 Ma). The Early Eocene Climatic Optimum terminated with a long-term cooling trend that culminated in continental-scale glaciation of Antarctica from 34 Ma onward. Whereas early studies attributed the Eocene transition from greenhouse to icehouse climates to the tectonic opening of Southern Ocean gateways, more recent investigations invoked a dominant role of declining atmospheric greenhouse gas concentrations (e.g., CO2). However, the scarcity of field data has prevented empirical evaluation of these hypotheses. We present marine microfossil and organic geochemical records spanning the early-to-middle Eocene transition from the Wilkes Land Margin, East Antarctica. Dinoflagellate biogeography and sea surface temperature paleothermometry reveal that the earliest throughflow of a westbound Antarctic Counter Current began ∼49–50 Ma through a southern opening of the Tasmanian Gateway. This early opening occurs in conjunction with the simultaneous onset of regional surface water and continental cooling (2–4 °C), evidenced by biomarker- and pollen-based paleothermometry. We interpret that the westbound flowing current flow across the Tasmanian Gateway resulted in cooling of Antarctic surface waters and coasts, which was conveyed to global intermediate waters through invigorated deep convection in southern high latitudes. Although atmospheric CO2 forcing alone would provide a more uniform middle Eocene cooling, the opening of the Tasmanian Gateway better explains Southern Ocean surface water and global deep ocean cooling in the apparent absence of (sub-) equatorial cooling. PMID:23720311

  19. Adolescence as a gateway to adult health outcomes.

    PubMed

    Raphael, Dennis

    2013-06-01

    Adolescence has long been regarded as a transition from childhood to adulthood. More recently it is become a concern of those wishing to avoid adverse health outcomes during middle and late adulthood. Most of this effort has been focused on behavioural risk factors such as tobacco and excessive alcohol use, physical exercise habits, dietary habits, as well as sexual and injury-related behaviours. The concern is that these habits are established during adolescence, continue into adulthood, and come to constitute ongoing risk factors for adverse health outcomes during middle and late adulthood. There is good reason to criticize this approach. These behaviours are themselves shaped by adolescents' living and working conditions and even then constitute a small proportion of the variance predicting adverse health outcomes during adulthood. More complex models of how adolescence serves as a gateway to adult health outcomes are presented. These are the socio-environmental, public policy, and political economy approaches. The argument is made that adolescence is a period during which public policy plays an especially important role in predicting future health outcomes. Yet, these public policies influence health all across the life span with adolescence providing only one of many important periods during which public policy shapes health prospects during middle and later adulthood. Ultimately one should consider a range of approaches ranging from the behavioural to the political to examine how adolescence serves as a gateway towards future adult prospects. An Adolescent Gateway Towards Adult Health Model is provided to assist in this process.

  20. Late neogene history of the Pacific-Caribbean gateway

    USGS Publications Warehouse

    Keller, G.; Zenker, C.E.; Stone, S.M.

    1989-01-01

    Planktic foraminiferal provinces of Caribbean DSDP Hole 502A and East Pacific DSDP Hole 503A have been analyzed and compared with benthic and planktic isotope records, carbonate, hiatus events, and sea level changes. Four major events are evident in the closure history of the Pacific-Caribbean gateway, at 6.2, 4.2, 2.4 and 1.8 Ma. The faunal change at 6.2 Ma coincides with the ??13C shift and is primarily caused by upwelling in the western Caribbean. This suggests restricted circulation of intermediate water and deflection northeastward, strengthening the Gulf Stream as reflected in the first major erosion on Blake Plateau. The second faunal change, at 4.2 Ma, coincides with increased surface water salinity evident in ??18O data and indicates increasingly restricted surface water exchange. Divergence of faunal provinces beginning at 2.4 Ma is marked by increasing abundance of high salinity tolerant species (Globigerinoides ruber) in the Caribbean. This suggests that initial closure of the Pacific-Caribbean gateway and cessation of sustained surface current flow between the Pacific and Caribbean occurred as late as 2.4 Ma. Maximum divergence of faunal provinces begins at 1.8 Ma and continues to the present. This implies that at least incipient littoral-neritic leakage occurred across the Pacific-Caribbean gateway between 2.4 and 1.8 Ma, with final closure by 1.8 Ma. ?? 1989.

  1. Van Allen Probes Science Gateway: A Centralized Data Access Point

    NASA Astrophysics Data System (ADS)

    Romeo, G.; Barnes, R. J.; Ukhorskiy, A. Y.; Sotirelis, T.; Stephens, G. K.; Kessel, R.; Potter, M.

    2015-12-01

    The Van Allen Probes Science Gateway acts a centralized interface to the instrument Science Operation Centers (SOCs), provides mission planning tools, and hosts a number of science related activities such as the mission bibliography. Most importantly, the Gateway acts as the primary site for processing and delivering the Van Allen Probes Space Weather data to users. Over the past years, the web-site has been completely redesigned with the focus on easier navigation and improvements of the existing tools such as the orbit plotter, position calculator and magnetic footprint tool. In addition, a new data plotting facility has been added. Based on HTML5, which allows users to interactively plot Van Allen Probes science and space weather data. The user can tailor the tool to display exactly the plot they wish to see and then share this with other users via either a URL or by QR code. Various types of plots can be created, including, simple time series, data plotted as a function of orbital location, and time versus L-Shell, capability of visualizing data from both probes (A & B) on the same plot. In cooperation with all Van Allen Probes Instrument SOCs, the Science Gateway will soon be able to serve higher level data products (Level 3), and to visualize them via the above mentioned HTML5 interface. Users will also be able to create customized CDF files on the fly.

  2. Van Allen Probes Science Gateway and Space Weather Data Processing

    NASA Astrophysics Data System (ADS)

    Romeo, G.; Barnes, R. J.; Weiss, M.; Fox, N. J.; Mauk, B.; Potter, M.; Kessel, R.

    2014-12-01

    The Van Allen Probes Science Gateway acts as a centralized interface to the instrument Science Operation Centers (SOCs), provides mission planning tools, and hosts a number of science related activities such as the mission bibliography. Most importantly, the Gateway acts as the primary site for processing and delivering the VAP Space Weather data to users. Over the past year, the web-site has been completely redesigned with the focus on easier navigation and improvements of the existing tools such as the orbit plotter, position calculator and magnetic footprint tool. In addition, a new data plotting facility has been added. Based on HTML5, which allows users to interactively plot Van Allen Probes summary and space weather data. The user can tailor the tool to display exactly the plot they wish to see and then share this with other users via either a URL or by QR code. Various types of plots can be created, including simple time series, data plotted as a function of orbital location, and time versus L-Shell. We discuss the new Van Allen Probes Science Gateway and the Space Weather Data Pipeline.

  3. Early experiences in developing and managing the neuroscience gateway

    PubMed Central

    Sivagnanam, Subhashini; Majumdar, Amit; Yoshimoto, Kenneth; Astakhov, Vadim; Bandrowski, Anita; Martone, MaryAnn; Carnevale, Nicholas. T.

    2015-01-01

    SUMMARY The last few decades have seen the emergence of computational neuroscience as a mature field where researchers are interested in modeling complex and large neuronal systems and require access to high performance computing machines and associated cyber infrastructure to manage computational workflow and data. The neuronal simulation tools, used in this research field, are also implemented for parallel computers and suitable for high performance computing machines. But using these tools on complex high performance computing machines remains a challenge because of issues with acquiring computer time on these machines located at national supercomputer centers, dealing with complex user interface of these machines, dealing with data management and retrieval. The Neuroscience Gateway is being developed to alleviate and/or hide these barriers to entry for computational neuroscientists. It hides or eliminates, from the point of view of the users, all the administrative and technical barriers and makes parallel neuronal simulation tools easily available and accessible on complex high performance computing machines. It handles the running of jobs and data management and retrieval. This paper shares the early experiences in bringing up this gateway and describes the software architecture it is based on, how it is implemented, and how users can use this for computational neuroscience research using high performance computing at the back end. We also look at parallel scaling of some publicly available neuronal models and analyze the recent usage data of the neuroscience gateway. PMID:26523124

  4. Expansion of the gateway multisite recombination cloning toolkit.

    PubMed

    Shearin, Harold K; Dvarishkis, Alisa R; Kozeluh, Craig D; Stowers, R Steven

    2013-01-01

    Precise manipulation of transgene expression in genetic model organisms has led to advances in understanding fundamental mechanisms of development, physiology, and genetic disease. Transgene construction is, however, a precondition of transgene expression, and often limits the rate of experimental progress. Here we report an expansion of the modular Gateway MultiSite recombination-cloning platform for high efficiency transgene assembly. The expansion includes two additional destination vectors and entry clones for the LexA binary transcription system, among others. These new tools enhance the expression levels possible with Gateway MultiSite generated transgenes and make possible the generation of LexA drivers and reporters with Gateway MultiSite cloning. In vivo data from transgenic Drosophila functionally validating each novel component are presented and include neuronal LexA drivers, LexAop2 red and green fluorescent synaptic vesicle reporters, TDC2 and TRH LexA, GAL4, and QF drivers, and LexAop2, UAS, and QUAS channelrhodopsin2 T159C reporters.

  5. Bibliographic Post-Processing with the TIS (Technology Information System) Intelligent Gateway: Analytical and Communication Capabilities.

    DTIC Science & Technology

    1985-09-01

    nucleosynthesis - Gateway to the very early universe AUTH: ’A/TURNER. M. S. PAA: A/(Chicago. University, Chicago. IL) (American Institute of Physics, NASA. NSF...TITLE> Big bang nucleosynthesis - Gateway to the very early universe <AUTHORS> TURNER. M. S. <PAA> A/(Chicogo, University, Chicago. IL) <PUB DESC...of the electronic states involved in the one- and two-photon processes is also discussed. Big bang nucleosynthesis - Gateway to the very early

  6. Improving Evaluation in the Nonprofit Sector: The Promise of Evaluation Capacity Building for Nonprofit Social Service Organizations in an Age of Accountability

    ERIC Educational Resources Information Center

    Pejsa, Laura J.

    2011-01-01

    The purpose of this study was to explore the real-world practice of evaluation capacity building (ECB) in the small-medium sized nonprofit context. The study aimed to map the activities, processes, and outcomes of ECB in these nonprofits in light of the competing external and internal evaluation contexts facing nonprofits in an age of…

  7. Should It Stay or Should It Go: How Successful Superintendents Build, Shift, and Transform District Culture in an Age of Increasing Accountability

    ERIC Educational Resources Information Center

    Arnold, Joshua F.

    2013-01-01

    The purpose of this study was to gain information regarding the manner in which superintendents build, shift, and transform district culture in an age of increasing accountability so that the new values and past practices of the organization work in concert with each other to match the culture of educational accountability sweeping the nation.…

  8. Gateway to College: Lessons from Implementing a Rigorous Academic Program for At-Risk Young People

    ERIC Educational Resources Information Center

    Willard, Jacklyn Altuna; Bayes, Brian; Martinez, John

    2015-01-01

    This study reports on the implementation of Gateway to College, a program whose mission is to serve students who have dropped out of high school, or who are at risk of dropping out of high school, by allowing them to earn a high school diploma and credits toward a postsecondary degree. Gateway to College is uniquely ambitious in providing…

  9. 78 FR 47410 - General Management Plan, Draft Environmental Impact Statement, Gateway National Recreation Area...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-05

    ... Recreation Area, New Jersey and New York AGENCY: National Park Service, Interior. ACTION: Notice of... Management Plan (GMP), Gateway National Recreation Area (Gateway), New York. The draft describes and analyzes several alternatives to guide the management of the site over the next 20 years. The NPS...

  10. An Analysis of Gateway Technical College Instructors' Opinions on Secondary and Postsecondary Program Alignment

    ERIC Educational Resources Information Center

    Albrecht, Bryan D.

    2011-01-01

    The purpose of this study was to determine what opinions Gateway Technical College instructors had toward secondary and postsecondary program alignment. Student transition is critical to supporting the mission and vision of Gateway Technical College. The impetus for this study was twofold. First, the quality improvement process established at…

  11. 75 FR 3224 - Dominion Transmission, Inc.; Notice of Public Scoping Meetings for the Appalachian Gateway Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ... firm transportation services from increasing gas production in the Appalachian region of West Virginia... Appalachian Gateway Project January 8, 2010. The staff of the Federal Energy Regulatory Commission (FERC or... Appalachian Gateway Project involving construction and operation of facilities by Dominion Transmission,...

  12. Aging

    PubMed Central

    Park, Dong Choon

    2013-01-01

    Aging is initiated based on genetic and environmental factors that operate from the time of birth of organisms. Aging induces physiological phenomena such as reduction of cell counts, deterioration of tissue proteins, tissue atrophy, a decrease of the metabolic rate, reduction of body fluids, and calcium metabolism abnormalities, with final progression onto pathological aging. Despite the efforts from many researchers, the progression and the mechanisms of aging are not clearly understood yet. Therefore, the authors would like to introduce several theories which have gained attentions among the published theories up to date; genetic program theory, wear-and-tear theory, telomere theory, endocrine theory, DNA damage hypothesis, error catastrophe theory, the rate of living theory, mitochondrial theory, and free radical theory. Although there have been many studies that have tried to prevent aging and prolong life, here we introduce a couple of theories which have been proven more or less; food, exercise, and diet restriction. PMID:24653904

  13. ZigBee device management system using web gateway

    NASA Astrophysics Data System (ADS)

    Choi, Yongsoon; Kim, Seonghoon; Park, Hong-Seong

    2007-12-01

    ZigBee technology that is observed to radio network of low electric power with latest WPAN's IEEE 802.15.4 technologies is evaluated as best technology for sensor network and digital home network construction. These fields require using application for monitoring, managing, controlling and organizing these nodes. However, these programs have a weakness that is hard to construct flexible system with Internet. This paper will use web server linked with gateway to manage sensor network that is consisted of ZigBee node and design system that manages ZigBee device with relative fast responsibility using AJAX web technology.

  14. Lyceum: A Multi-Protocol Digital Library Gateway

    NASA Technical Reports Server (NTRS)

    Maa, Ming-Hokng; Nelson, Michael L.; Esler, Sandra L.

    1997-01-01

    Lyceum is a prototype scalable query gateway that provides a logically central interface to multi-protocol and physically distributed, digital libraries of scientific and technical information. Lyceum processes queries to multiple syntactically distinct search engines used by various distributed information servers from a single logically central interface without modification of the remote search engines. A working prototype (http://www.larc.nasa.gov/lyceum/) demonstrates the capabilities, potentials, and advantages of this type of meta-search engine by providing access to over 50 servers covering over 20 disciplines.

  15. The MIM web gateway to IP multicast e-meetings

    NASA Astrophysics Data System (ADS)

    Parviainen, Roland; Parnes, Peter

    2003-12-01

    As video conferencing and e-meeting systems are used more and more on the Internet and in businesses it becomes increasingly important to be able to participate from any computer at any location. Often this is impossible, since these systems requires often special software that are not available everywhere or impossible to install for administrative reasons. Many locations also lack the necessary network infrastructure such as IP multicast. This paper presents a WWW gateway system that enables users to participate using only a standard web browser. The design and architecture of the system are described and performance tests that show the scalability of the system are also presented.

  16. Time Dependent Hartree Fock Equation: Gateway to Nonequilibrium Plasmas

    SciTech Connect

    James W. Dufty

    2007-04-28

    This is the Final Technical Report for DE-FG02-2ER54677 award “Time Dependent Hartree Fock Equation - Gateway to Nonequilibrium Plasmas”. Research has focused on the nonequilibrium dynamics of electrons in the presence of ions, both via basic quantum theory and via semi-classical molecular dynamics (MD) simulation. In addition, fundamental notions of dissipative dynamics have been explored for models of grains and dust, and for scalar fields (temperature) in turbulent edge plasmas. The specific topics addressed were Quantum Kinetic Theory for Metallic Clusters, Semi-classical MD Simulation of Plasmas , and Effects of Dissipative Dynamics.

  17. 77 FR 20046 - Establishment of the Gateway National Recreation Area Fort Hancock 21st Century Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-03

    ... Establishment of the Gateway National Recreation Area Fort Hancock 21st Century Advisory Committee AGENCY... Interior (Secretary) is announcing the establishment of the Gateway National Recreation Area Fort Hancock... relating to future uses of the Fort Hancock Historic Landmark District of Gateway National Recreation...

  18. Survey on Existing Science Gateways - Based on DEGREE

    NASA Astrophysics Data System (ADS)

    Schwichtenberg, Horst; Claus, Steffen

    2010-05-01

    Science Gateways gather community-developed specific tools, applications, and data that is usually combined and presented in a graphical user interface which is customized to the needs of the target user community. Science Gateways serve as a single point of entry for the users and are usually represented by fat clients or web portals. Part of the DEGREE project (Dissemination and Exploitation of Grids in Earth Science) was a state-of-the-art survey of portal usage in Earth Science (ES) applications. This survey considered a list of 29 portals, including 17 ES portals and 12 generic developments coming from outside of the ES domain. The survey identified three common usage types of ES portals, including data dissemination (e.g. observational data), collaboration as well as usage of Grid-based resources (e.g. for processing of ES datasets). Based on these three usage types, key requirements could be extracted. These requirements were furthermore used for a feature comparison with existing portal developments coming from outside of the ES domain. This presentation gives an overview of the results of the survey (including a feature comparison of ES and non-ES portals). Furthermore, three portals are discussed in detail, one for each usage type (data dissemination, collaboration, Grid-based).

  19. Design on intelligent gateway technique in home network

    NASA Astrophysics Data System (ADS)

    Hu, Zhonggong; Feng, Xiancheng

    2008-12-01

    Based on digitization, multimedia, mobility, wide band, real-time interaction and so on,family networks, because can provide diverse and personalized synthesis service in information, correspondence work, entertainment, education and health care and so on, are more and more paid attention by the market. The family network product development has become the focus of the related industry. In this paper,the concept of the family network and the overall reference model of the family network are introduced firstly.Then the core techniques and the correspondence standard related with the family network are proposed.The key analysis is made for the function of family gateway, the function module of the software,the key technologies to client side software architecture and the trend of development of the family network entertainment seeing and hearing service and so on. Product present situation of the family gateway and the future trend of development, application solution of the digital family service are introduced. The development of the family network product bringing about the digital family network industry is introduced finally.It causes the development of software industries,such as communication industry,electrical appliances industry, computer and game and so on.It also causes the development of estate industry.

  20. E-DECIDER Decision Support Gateway For Earthquake Disaster Response

    NASA Astrophysics Data System (ADS)

    Glasscoe, M. T.; Stough, T. M.; Parker, J. W.; Burl, M. C.; Donnellan, A.; Blom, R. G.; Pierce, M. E.; Wang, J.; Ma, Y.; Rundle, J. B.; Yoder, M. R.

    2013-12-01

    Earthquake Data Enhanced Cyber-Infrastructure for Disaster Evaluation and Response (E-DECIDER) is a NASA-funded project developing capabilities for decision-making utilizing remote sensing data and modeling software in order to provide decision support for earthquake disaster management and response. E-DECIDER incorporates earthquake forecasting methodology and geophysical modeling tools developed through NASA's QuakeSim project in order to produce standards-compliant map data products to aid in decision-making following an earthquake. Remote sensing and geodetic data, in conjunction with modeling and forecasting tools, help provide both long-term planning information for disaster management decision makers as well as short-term information following earthquake events (i.e. identifying areas where the greatest deformation and damage has occurred and emergency services may need to be focused). E-DECIDER utilizes a service-based GIS model for its cyber-infrastructure in order to produce standards-compliant products for different user types with multiple service protocols (such as KML, WMS, WFS, and WCS). The goal is to make complex GIS processing and domain-specific analysis tools more accessible to general users through software services as well as provide system sustainability through infrastructure services. The system comprises several components, which include: a GeoServer for thematic mapping and data distribution, a geospatial database for storage and spatial analysis, web service APIs, including simple-to-use REST APIs for complex GIS functionalities, and geoprocessing tools including python scripts to produce standards-compliant data products. These are then served to the E-DECIDER decision support gateway (http://e-decider.org), the E-DECIDER mobile interface, and to the Department of Homeland Security decision support middleware UICDS (Unified Incident Command and Decision Support). The E-DECIDER decision support gateway features a web interface that

  1. Design and implementation of scalable IPv4-IPv6 internetworking gateway

    NASA Astrophysics Data System (ADS)

    Zhu, Guo-sheng; Yu, Shao-hua; Dai, Jin-you

    2008-11-01

    This paper proposed a scalable architecture of IPv4-IPv6 internetworking gateway based on EZchip 10Gbps network processor NP-1c. The Application Layer Gateway(ALG) of control plane can be upgraded without needing to modify the data forwarding plane.A SIP ALG of 3GPP IMS(IP Multimedia Subsystem)was implemented and tested under real China Next Generation Internet(CNGI) network environment.IPv4 SIP UEs can communicate with IPv6 SIP UEs through the gateway.

  2. An exploration of the gateway math and science course relationships in the Los Angeles Community College District

    NASA Astrophysics Data System (ADS)

    Buchanan, Donald G.

    This study evaluated selected demographic, pre-enrollment, and economic status variables in comparison to college-level performance factors of GPA and course completion ratios for gateway math and science courses. The Transfer and Retention of Urban Community College Students (TRUCCS) project team collected survey and enrollment data for this study in the Los Angeles Community College District (LACCD). The TRUCCS team surveyed over 5,000 students within the nine campus district beginning in the fall of 2000 and spring of 2001 with follow-up data for next several years. This study focused on the math and science courses; established background demographics; evaluated pre-enrollment high school self-reported grades; reviewed high school and college level math courses taken; investigated specific gateway courses of biology, chemistry and physics; and compared them to the overall GPAs and course completion ratios for 4,698 students. This involved the SPSS development of numerous statistical products including the data from frequency distributions, means, cross-tabulations, group statistics t-tests, independent samples t-tests, and one-way ANOVA. Findings revealed demographic and economic relationships of significance for students' performance factors of GPA and course completion ratios. Furthermore, findings revealed significant differences between the gender, age, ethnicity and economic employment relationships. Conclusions and implications for institutions of higher education were documented. Recommendations for dissemination, intervention programs, and future research were also discussed.

  3. Intelligent Document Gateway: A Service System Case Study and Analysis

    NASA Astrophysics Data System (ADS)

    Krishna, Vikas; Lelescu, Ana

    In today's fast paced world, it is necessary to process business ­documents expediently, accurately, and diligently. In other words, processing has to be fast, errors must be prevented (or caught and corrected quickly), and documents cannot be lost or misplaced. The failure to meet these criteria, depending on the type and purpose of the documents, can have serious business, legal, or safety consequences. In this paper, we evaluated a B2B order placement service system that allows clients to place orders for products and services over a network. We describe the order placement service before and after deploying the Intelligent Document Gateway (IDG), a document-centric business process automation technology from IBM Research. Using service science perspective and service systems frameworks, we provide an analysis of how IDG improved the value proposition for both the service providers and service clients.

  4. Network gateway security method for enterprise Grid: a literature review

    NASA Astrophysics Data System (ADS)

    Sujarwo, A.; Tan, J.

    2017-03-01

    The computational Grid has brought big computational resources closer to scientists. It enables people to do a large computational job anytime and anywhere without any physical border anymore. However, the massive and spread of computer participants either as user or computational provider arise problems in security. The challenge is on how the security system, especially the one which filters data in the gateway could works in flexibility depends on the registered Grid participants. This paper surveys what people have done to approach this challenge, in order to find the better and new method for enterprise Grid. The findings of this paper is the dynamically controlled enterprise firewall to secure the Grid resources from unwanted connections with a new firewall controlling method and components.

  5. DNSLab: A gateway to turbulent flow simulation in Matlab

    NASA Astrophysics Data System (ADS)

    Vuorinen, V.; Keskinen, K.

    2016-06-01

    Computational fluid dynamics (CFD) research is increasingly much focused towards computationally intensive, eddy resolving simulation techniques of turbulent flows such as large-eddy simulation (LES) and direct numerical simulation (DNS). Here, we present a compact educational software package called DNSLab, tailored for learning partial differential equations of turbulence from the perspective of DNS in Matlab environment. Based on educational experiences and course feedback from tens of engineering post-graduate students and industrial engineers, DNSLab can offer a major gateway to turbulence simulation with minimal prerequisites. Matlab implementation of two common fractional step projection methods is considered: the 2d Fourier pseudo-spectral method, and the 3d finite difference method with 2nd order spatial accuracy. Both methods are based on vectorization in Matlab and the slow for-loops are thus avoided. DNSLab is tested on two basic problems which we have noted to be of high educational value: 2d periodic array of decaying vortices, and 3d turbulent channel flow at Reτ = 180. To the best of our knowledge, the present study is possibly the first to investigate efficiency of a 3d turbulent, wall bounded flow in Matlab. The accuracy and efficiency of DNSLab is compared with a customized OpenFOAM solver called rk4projectionFoam. Based on our experiences and course feedback, the main contribution of DNSLab consists of the following features. (i) The very compact Matlab implementation of present Navier-Stokes solvers provides a gateway to efficient learning of both, physics of turbulent flows, and simulation of turbulence. (ii) Only relatively minor prerequisites on fluid dynamics and numerical methods are required for using DNSLab. (iii) In 2d, interactive results for turbulent flow cases can be obtained. Even for a 3d channel flow, the solver is fast enough for nearly interactive educational use. (iv) DNSLab is made openly available and thus contributing to

  6. Design of an Open Smart Energy Gateway for Smart Meter Data Management

    SciTech Connect

    Page, Janie; McParland, Chuck; Piette, Mary Ann; Czarnecki, Stephen

    2015-03-01

    With the widespread deployment of electronic interval meters, commonly known as smart meters, came the promise of real-time data on electric energy consumption. Recognizing an opportunity to provide consumers access to their near real-time energy consumption data directly from their installed smart meter, we designed a mechanism for capturing those data for consumer use via an open smart energy gateway (OpenSEG). By design, OpenSEG provides a clearly defined boundary for equipment and data ownership. OpenSEG is an open-source data management platform to enable better data management of smart meter data. Effectively, it is an information architecture designed to work with the ZigBee Smart Energy Profile 1.x (SEP 1.x). It was specifically designed to reduce cyber-security risks and provide secure information directly from smart meters to consumers in near real time, using display devices already owned by the consumers. OpenSEG stores 48 hours of recent consumption data in a circular cache using a format consistent with commonly available archived (not real-time) consumption data such as Green Button, which is based on the Energy Services Provider Interface (ESPI) data standard. It consists of a common XML format for energy usage information and a data exchange protocol to facilitate automated data transfer upon utility customer authorization. Included in the design is an application program interface by which users can acquire data from OpenSEG for further post processing. A sample data display application is included in the initial software product. The data display application demonstrates that OpenSEG can help electricity use data to be retrieved from a smart meter and ported to a wide variety of user-owned devices such as cell phones or a user-selected database. This system can be used for homes, multi-family buildings, or small commercial buildings in California.

  7. 78 FR 69432 - National Institute on Aging; Cancellation of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-19

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Cancellation of Meeting Notice is hereby given of the cancellation of the National Institute on Aging Special Emphasis Panel, December 18, 2013, 2:00 p.m. to December 18, 2013, 3:15 p.m., National Institute of Aging, Gateway...

  8. 77 FR 21996 - Certain Equipment for Communications Networks, Including Switches, Routers, Gateways, Bridges...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-12

    ... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION Certain Equipment for Communications Networks, Including Switches, Routers, Gateways, Bridges... States after importation of certain equipment for communications networks, including switches,...

  9. 76 FR 48834 - Michigan Consolidated Gas Company and Dawn Gateway Pipeline, LLC; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-09

    ... Bering, Director, Marketing & Optimization, DTE Pipeline/Dawn Gateway LLC, One Energy Plaza, Detroit, MI... its environmental assessment (EA) and place it into the Commission's public record (eLibrary) for...

  10. Communication-Gateway Software For NETEX, DECnet, And TCP/IP

    NASA Technical Reports Server (NTRS)

    Keith, B.; Ferry, D.; Fendler, E.

    1990-01-01

    Communications gateway software, GATEWAY, provides process-to-process communication between remote applications programs in different protocol domains. Communicating peer processes may be resident on any paired combination of NETEX, DECnet, or TCP/IP hosts. Provides necessary mapping from one protocol to another and facilitates practical intermachine communications in cost-effective manner by eliminating need to standardize on single protocol or to implement multiple protocols in host computers. Written in Ada.

  11. Transferable Output ASCII Data (TOAD) gateway: Version 1.0 user's guide

    NASA Technical Reports Server (NTRS)

    Bingel, Bradford D.

    1991-01-01

    The Transferable Output ASCII Data (TOAD) Gateway, release 1.0 is described. This is a software tool for converting tabular data from one format into another via the TOAD format. This initial release of the Gateway allows free data interchange among the following file formats: TOAD; Standard Interface File (SIF); Program to Optimize Simulated Trajectories (POST) input; Comma Separated Value (TSV); and a general free-form file format. As required, additional formats can be accommodated quickly and easily.

  12. A suite of Gateway cloning vectors for high-throughput genetic analysis in Saccharomyces cerevisiae.

    PubMed

    Alberti, Simon; Gitler, Aaron D; Lindquist, Susan

    2007-10-01

    In the post-genomic era, academic and biotechnological research is increasingly shifting its attention from single proteins to the analysis of complex protein networks. This change in experimental design requires the use of simple and experimentally tractable organisms, such as the unicellular eukaryote Saccharomyces cerevisiae, and a range of new high-throughput techniques. The Gateway system has emerged as a powerful high-throughput cloning method that allows for the in vitro recombination of DNA with high speed, accuracy and reliability. Two Gateway-based libraries of overexpression plasmids containing the entire complement of yeast open reading frames (ORFs) have recently been completed. In order to make use of these powerful resources, we adapted the widely used pRS series of yeast shuttle vectors for use in Gateway-based cloning. The resulting suite of 288 yeast Gateway vectors is based upon the two commonly used GPD and GAL1 promoter expression systems that enable expression of ORFs, either constitutively or under galactose-inducible conditions. In addition, proteins of interest can be fused to a choice of frequently used N- or C-terminal tags, such as EGFP, ECFP, EYFP, Cerulean, monomeric DsRed, HA or TAP. We have made this yeast Gateway vector kit available to the research community via the non-profit Addgene Plasmid Repository (http://www.addgene.org/yeast_gateway).

  13. Flood risk and insurance loss potential in the Thames Gateway

    NASA Astrophysics Data System (ADS)

    Eldridge, J.; Horn, D.

    2009-04-01

    The Thames Gateway, currently Europe's largest regeneration project, is an area of redevelopment located in the South East of England, with Government plans to create up to 160,000 new homes and 180,000 new jobs by 2016. Although the new development is intended to contribute £12bn annually to the economy, the potential flood risk is high, with much of the area situated on Thames tidal floodplain and vulnerable to both storm surges and peak river flows. This poses significant hazard to those inhabiting the area and has raised concern amongst the UK insurance industry, who would be liable for significant financial claims if a large flood event were to occur, particularly with respect to the number of new homes and businesses being built in flood risk areas. Flood risk and the potential damage to both lives and assets in vulnerable areas have gained substantial recognition, in light of recent flooding events, from both governmental agencies and in the public's awareness of flood hazard. This has resulted in a change in UK policy with planning policy for flood risk (PPS25, Planning Policy Statement 25) adopting a more strategic approach to development, as well as a new Flooding and Water Bill which is due for consultation in 2009. The Government and the Association of British Insurers, who represent the UK insurance industry, have also recently changed their Statement of Principles which guides provision of flood insurance in the future. This PhD research project aims to quantify flood risk in the Thames Gateway area with a view to evaluating the insurance loss potential under different insurance and planning scenarios. Using current sources of inundation extent, and incorporating varying insurance penetration rates and degrees of adoption of planning policy and guidance, it focuses on estimating flood risk under these different scenarios. This presentation introduces the development of the project and the theory and methodology which will be used to address the

  14. The Development and Evaluation of a Professional Development Model to Build Meaningful and Effective IEPs for Transition-Aged Students

    ERIC Educational Resources Information Center

    Doren, Bonnie; Flannery, K. Brigid; Lombardi, Allison

    2012-01-01

    The purpose of the study was to examine the potential efficacy of a professional development training model targeting IEP case managers of transition-age students. A training model was developed and a pilot study conducted to understand the promise of the model to improve the development of critical components within the IEP document that support…

  15. Gateways of ventral and dorsal streams in mouse visual cortex

    PubMed Central

    Wang, Quanxin; Gao, Enquan; Burkhalter, Andreas

    2011-01-01

    It is widely held that the spatial processing functions underlying rodent navigation are similar to those encoding human episodic memory (Doeller et al, 2010). Spatial and nonspatial information are provided by all senses including vision. It has been suggested that visual inputs are fed to the navigational network in cortex and hippocampus through dorsal and ventral intracortical streams (Whitlock et al, 2008), but this has not been shown directly in rodents. We have used cyto- and chemoarchitectonic markers, topographic mapping of receptive fields and pathway tracing to determine in mouse visual cortex whether the lateromedial (LM) and the anterolateral fields (AL), which are the principal targets of primary visual cortex (V1) (Wang and Burkhalter, 2007) specialized for processing nonspatial and spatial visual information (Gao et al, 2006), are distinct areas with diverse connections. We have found that the LM/AL border coincides with a change in type 2 muscarinic acetylcholine receptor (m2AChR) expression in layer 4 and with the representation of the lower visual field periphery. Our quantitative analyses further show that LM strongly projects to temporal cortex as well as the lateral entorhinal cortex, which has weak spatial selectivity (Hargreaves et al, 2005). In contrast, AL has stronger connections with posterior parietal cortex, motor cortex and the spatially selective medial entorhinal cortex (Haftig et al, 2005). These results support the notion that LM and AL are architecturally, topographically and connectionally distinct areas of extrastriate visual cortex and that they are gateways for ventral and dorsal streams. PMID:21289200

  16. Integration of communications with the Intelligent Gateway Processor

    SciTech Connect

    Hampel, V.E.

    1986-01-01

    The Intelligent Gateway Processor (IGP) software is being used to interconnect users equipped with different personal computers and ASCII terminals to mainframe machines of different make. This integration is made possible by the IGP's unique user interface and networking software. Prototype systems of the table-driven, interpreter-based IGP have been adapted to very different programmatic requirements and have demonstrated substantial increases in end-user productivity. Procedures previously requiring days can now be carried out in minutes. The IGP software has been under development by the Technology Information Systems (TIS) program at Lawrence Livermore National Laboratory (LLNL) since 1975 and is in use by several federal agencies since 1983: The Air Force is prototyping applications which range from automated identification of spare parts for aircraft to office automation and the controlled storage and distribution of technical orders and engineering drawings. Other applications of the IGP are the Information Management System (IMS) for aviation statistics in the Federal Aviation Administration (FAA), the Nuclear Criticality Information System (NCIS) and a nationwide Cost Estimating System (CES) in the Department of Energy, the library automation network of the Defense Technical Information Center (DTIC), and the modernization program in the Office of the Secretary of Defense (OSD). 31 refs., 9 figs.

  17. Enabling Data Intensive Science through Service Oriented Science: Virtual Laboratories and Science Gateways

    NASA Astrophysics Data System (ADS)

    Lescinsky, D. T.; Wyborn, L. A.; Evans, B. J. K.; Allen, C.; Fraser, R.; Rankine, T.

    2014-12-01

    We present collaborative work on a generic, modular infrastructure for virtual laboratories (VLs, similar to science gateways) that combine online access to data, scientific code, and computing resources as services that support multiple data intensive scientific computing needs across a wide range of science disciplines. We are leveraging access to 10+ PB of earth science data on Lustre filesystems at Australia's National Computational Infrastructure (NCI) Research Data Storage Infrastructure (RDSI) node, co-located with NCI's 1.2 PFlop Raijin supercomputer and a 3000 CPU core research cloud. The development, maintenance and sustainability of VLs is best accomplished through modularisation and standardisation of interfaces between components. Our approach has been to break up tightly-coupled, specialised application packages into modules, with identified best techniques and algorithms repackaged either as data services or scientific tools that are accessible across domains. The data services can be used to manipulate, visualise and transform multiple data types whilst the scientific tools can be used in concert with multiple scientific codes. We are currently designing a scalable generic infrastructure that will handle scientific code as modularised services and thereby enable the rapid/easy deployment of new codes or versions of codes. The goal is to build open source libraries/collections of scientific tools, scripts and modelling codes that can be combined in specially designed deployments. Additional services in development include: provenance, publication of results, monitoring, workflow tools, etc. The generic VL infrastructure will be hosted at NCI, but can access alternative computing infrastructures (i.e., public/private cloud, HPC).The Virtual Geophysics Laboratory (VGL) was developed as a pilot project to demonstrate the underlying technology. This base is now being redesigned and generalised to develop a Virtual Hazards Impact and Risk Laboratory

  18. SU-D-BRD-03: A Gateway for GPU Computing in Cancer Radiotherapy Research

    SciTech Connect

    Jia, X; Folkerts, M; Shi, F; Yan, H; Yan, Y; Jiang, S; Sivagnanam, S; Majumdar, A

    2014-06-01

    Purpose: Graphics Processing Unit (GPU) has become increasingly important in radiotherapy. However, it is still difficult for general clinical researchers to access GPU codes developed by other researchers, and for developers to objectively benchmark their codes. Moreover, it is quite often to see repeated efforts spent on developing low-quality GPU codes. The goal of this project is to establish an infrastructure for testing GPU codes, cross comparing them, and facilitating code distributions in radiotherapy community. Methods: We developed a system called Gateway for GPU Computing in Cancer Radiotherapy Research (GCR2). A number of GPU codes developed by our group and other developers can be accessed via a web interface. To use the services, researchers first upload their test data or use the standard data provided by our system. Then they can select the GPU device on which the code will be executed. Our system offers all mainstream GPU hardware for code benchmarking purpose. After the code running is complete, the system automatically summarizes and displays the computing results. We also released a SDK to allow the developers to build their own algorithm implementation and submit their binary codes to the system. The submitted code is then systematically benchmarked using a variety of GPU hardware and representative data provided by our system. The developers can also compare their codes with others and generate benchmarking reports. Results: It is found that the developed system is fully functioning. Through a user-friendly web interface, researchers are able to test various GPU codes. Developers also benefit from this platform by comprehensively benchmarking their codes on various GPU platforms and representative clinical data sets. Conclusion: We have developed an open platform allowing the clinical researchers and developers to access the GPUs and GPU codes. This development will facilitate the utilization of GPU in radiation therapy field.

  19. 78 FR 51195 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-20

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Initial Review Group; Biological Aging Review Committee Date: October... Nakhai, Ph.D., Scientific Review Branch, National Institute On Aging, Gateway Bldg., 2C212,...

  20. Motor development of children and adolescents aged 8-16 years in view of their somatic build and objective quality of life of their families.

    PubMed

    Puciato, Daniel; Mynarski, Władysław; Rozpara, Michał; Borysiuk, Zbigniew; Szyguła, Renata

    2011-06-01

    The differences in human motor development are determined by predispositions and living conditions. The aim of the present study was to examine relationships between motor fitness of children and adolescents aged 8-16 years (277 boys and 247 girls), and their somatic build and quality of life of their families. Body height, body mass and skinfold thickness were measured. On the basis of these measurements body mass index (BMI), Rohrer's index and lean body mass (LBM) were calculated. The subjects' physical fitness was also assessed with motor tests: speed of arm movement (plate tapping), agility (10 x 5 m shuttle run), explosive strength of the legs (standing broad jump), trunk strength (situps), explosive strength of the trunk and shoulder girdle (1-kg medicine ball throw), and flexibility (sit and reach) regarded as a morpho-functional predisposition of motor abilities. The standing broad jump results were then used to calculate maximal anaerobic power (MPA). The examination was completed with a questionnaire survey of the children's parents concerning their families' quality of life. On the basis of the parents' answers to the questionnaire, two quality of life indices were constructed: objective quality of life index and subjective quality of life index. Due to the wide age bracket of subjects the sample was divided into two age groups: 8-12 and 13-16-year-olds. The relationships between subjects' motor development, somatic traits and their families' quality of life were examined with the use of multivariate comparative analysis. The level of motor development of studied children was more strongly determined by their somatic build than the quality of life of their families. The most important somatic determinants of the subjects' motor abilities were body height and subcutaneous adiposity. These determinants primarily affected speed and strength abilities of younger school children. Objective quality of life of children's families determined the development of

  1. Supporting Ecological Research With a Flexible Satellite Sensornet Gateway

    NASA Astrophysics Data System (ADS)

    Silva, F.; Rundel, P. W.; Graham, E. A.; Falk, A.; Ye, W.; Pradkin, Y.; Deschon, A.; Bhatt, S.; McHenry, T.

    2007-12-01

    Wireless sensor networks are a promising technology for ecological research due to their capability to make continuous and in-situ measurements. However, there are some challenges for the wide adoption of this technology by scientists, who may have various research focuses. First, the observation system needs to be rapidly and easily deployable at different remote locations. Second, the system needs to be flexible enough to meet the requirements of different applications and easily reconfigurable by scientists, who may not always be technology experts. To address these challenges, we designed and implemented a flexible satellite gateway for using sensor networks. Our first prototype is being deployed at Stunt Ranch in the Santa Monica Mountains to support biological research at UCLA. In this joint USC/ISI-UCLA deployment, scientists are interested in a long-term investigation of the influence of the 2006-07 southern California drought conditions on the water relations of important chaparral shrub and tree species that differ in their depth of rooting. Rainfall over this past hydrologic year in southern California has been less than 25% of normal, making it the driest year on record. In addition to core measurements of air temperature, relative humidity, wind speed, solar irradiance, rainfall, and soil moisture, we use constant-heating sap flow sensors to continuously monitor the flow of water through the xylem of replicated stems of four species to compare their access to soil moisture with plant water stress. Our gateway consists of a front-end data acquisition system and a back-end data storage system, connected by a long-haul satellite communication link. At the front-end, all environmental sensors are connected to a Compact RIO, a rugged data acquisition platform developed by National Instruments. Sap flow sensors are deployed in several locations that are 20 to 50 meters away from the Compact RIO. At each plant, a Hobo datalogger is used to collect sap flow

  2. Opening the gateways for diatoms primes Earth for Antarctic glaciation

    NASA Astrophysics Data System (ADS)

    Egan, Katherine E.; Rickaby, Rosalind E. M.; Hendry, Katharine R.; Halliday, Alex N.

    2013-08-01

    The abrupt onset of Antarctic glaciation during the Eocene-Oligocene Transition (∼33.7 Ma, Oi1) is linked to declining atmospheric pCO2 levels, yet the mechanisms that forced pCO2 decline remain elusive. Biogenic silicon cycling is inextricably linked to both long and short term carbon cycling through the diatoms, siliceous walled autotrophs which today account for up to 40% of primary production. It is hypothesised that during the Late Eocene a sharp rise in diatom abundance could have contributed to pCO2 drawdown and global cooling by increasing the proportion of organic carbon buried in marine sediment. Diatom and sponge silicon isotope ratios (δ30Si) are here combined for the first time to reconstruct the late Eocene-early Oligocene ocean silicon cycle and provide new insight into the role of diatom productivity in Antarctic glaciation. At ODP site 1090 in the Southern Ocean, a 0.6‰ rise in diatom δ30Si through the late Eocene documents increasing diatom silicic acid utilisation with high, near modern values attained by the earliest Oligocene. A concomitant 1.5‰ decline in sponge δ30Si at ODP site 689 on the Maud Rise tracks an approximate doubling of intermediate depth silicic acid concentration in the high southern latitudes. Intermediate depth silicic acid concentration peaked at ∼31.5 Ma, coincident with the final establishment of a deepwater pathway through the Tasman Gateway and Drake Passage. These results suggest that upwelling intensification related to the spin-up of a circum-Antarctic current may have driven late Eocene diatom proliferation. Organic carbon burial associated with higher diatom abundance and export provides a mechanism that can account for pCO2 drawdown not only at, but also prior to, Antarctic glaciation as required by a pCO2 'threshold' mechanism for ice sheet growth.

  3. Soiling of building envelope surfaces and its effect on solar reflectance – Part II: Development of an accelerated aging method for roofing materials

    SciTech Connect

    Sleiman, Mohamad; Kirchstetter, Thomas W.; Berdahl, Paul; Gilbert, Haley E.; Quelen, Sarah; Marlot, Lea; Preble, Chelsea V.; Chen, Sharon; Montalbano, Amandine; Rosseler, Olivier; Akbari, Hashem; Levinson, Ronnen; Destaillats, Hugo

    2014-01-09

    Highly reflective roofs can decrease the energy required for building air conditioning, help mitigate the urban heat island effect, and slow global warming. However, these benefits are diminished by soiling and weathering processes that reduce the solar reflectance of most roofing materials. Soiling results from the deposition of atmospheric particulate matter and the growth of microorganisms, each of which absorb sunlight. Weathering of materials occurs with exposure to water, sunlight, and high temperatures. This study developed an accelerated aging method that incorporates features of soiling and weathering. The method sprays a calibrated aqueous soiling mixture of dust minerals, black carbon, humic acid, and salts onto preconditioned coupons of roofing materials, then subjects the soiled coupons to cycles of ultraviolet radiation, heat and water in a commercial weatherometer. Three soiling mixtures were optimized to reproduce the site-specific solar spectral reflectance features of roofing products exposed for 3 years in a hot and humid climate (Miami, Florida); a hot and dry climate (Phoenix, Arizona); and a polluted atmosphere in a temperate climate (Cleveland, Ohio). A fourth mixture was designed to reproduce the three-site average values of solar reflectance and thermal emittance attained after 3 years of natural exposure, which the Cool Roof Rating Council (CRRC) uses to rate roofing products sold in the US. This accelerated aging method was applied to 25 products₋single ply membranes, factory and field applied coatings, tiles, modified bitumen cap sheets, and asphalt shingles₋and reproduced in 3 days the CRRC's 3-year aged values of solar reflectance. In conclusion, this accelerated aging method can be used to speed the evaluation and rating of new cool roofing materials.

  4. New insights into late Neogene glacial dynamics, tectonics, and hydrocarbon migrations in the Atlantic-Arctic gateway region.

    NASA Astrophysics Data System (ADS)

    Knies, J.; Baranwal, S.; Fabian, K.; Grøsfjeld, K.; Andreassen, K.; Husum, K.; Mattingsdal, R.; Gaina, C.; De Schepper, S.; Vogt, C.; Andersen, N.

    2012-04-01

    Notwithstanding the recent IODP drilling on the Lomonosov Ridge, the Late Cenozoic history of the Arctic Ocean still remains elusive. The tectonic processes leading to the development of the only deep-water connection to the Arctic Ocean via the Fram Strait are still poorly understood. Also, the influence of the gateway region on changes in Arctic-Atlantic ocean circulation, uplift/erosion on the adjacent hinterland, as well as glacial initiation and its consequences for the petroleum systems in the regions, remain unclear. By revisiting Ocean Drilling Program (ODP) Leg 151, holes 911A and 910C and interpreting new multi-channel seismic data, we have now established a new comprehensive chronological framework for the Yermak Plateau and revealed important paleoenvironmental changes for the Atlantic-Arctic gateway during the late Neogene. The improved chronostratigraphic framework is established through continuous paleomagnetic and biostratigraphic data as well as selected intervals with stable ?18O and ?13C data derived from benthic foraminifera Cassidulina teretis. Supported by acoustic profiling, the new data indicate a continuous late Miocene/early Pliocene age (~5-6 Ma) for the base of both holes. The depositional regime north (Yermak Plateau) and south of the Fram Strait (Hovgaard Ridge) was rather shallow during the late Miocene and water mass exchange between the Arctic and Atlantic was restricted. Ice sheets on the Svalbard Platform evolved during the late Miocene, however did not reach the coastline before 3.3 Ma. Migration of gaseous hydrocarbons occurred prior to the intensification of the Northern Hemisphere Glaciations (~2.7 Ma) as indicated by high-amplitude reflections, corroborating the occurrence of greigite mineralization and stable carbon isotope excursions in planktic/benthic foraminifera. The data indicate that Pleistocene erosion and uplift in the Barents Sea region had probably only minor effects on reservoir leakages than previously thought.

  5. 76 FR 51462 - Notice of Release of an Easement Restriction at Phoenix-Mesa Gateway Airport, Mesa, AZ

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-18

    ... TRANSPORTATION Federal Aviation Administration Notice of Release of an Easement Restriction at Phoenix-Mesa... acres of property abutting Phoenix-Mesa Gateway, Mesa, Arizona, from all conditions contained in a grant..., Phoenix-Gateway Airport Authority, 5835 S. Sossaman Road, Mesa, Arizona 85212, Telephone: (480)...

  6. 77 FR 58531 - Notice of Intent To Prepare a Joint Environmental Impact Statement (EIS) for the Gateway Pacific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-21

    ... Impact Statement (EIS) for the Gateway Pacific Terminals Bulk Dry Goods Shipping Facility and the Custer... Pacific International Terminal, Inc.'s Gateway Pacific Terminal (GPT) and Burlington Northern Santa Fe..., northwest of Ferndale and south of Birch Bay in an area called Cherry Point. Pacific International...

  7. Residential Segregation in Metropolitan Established Immigrant Gateways and New Destinations, 1990–2000*

    PubMed Central

    Park, Julie; Iceland, John

    2014-01-01

    In the 1990s, many immigrants bypassed established gateways like Los Angeles, New York, Chicago, and Miami to create new immigrant destinations across the U.S. In this paper, we examine how segregation and spatial assimilation might differ between established gateways and new destinations among the 150 largest metropolitan areas. Using data from the 1990 and 2000 censuses, we calculate levels of dissimilarity for Hispanics and Asians by nativity for these two gateway types. Our findings show that segregation levels are consistently lower in new destinations. However, Hispanics in new destinations experienced significant increases segregation during the 1990s, suggesting a convergence in residential patterns by destination type. Nevertheless, in both destinations the native-born are less segregated than the foreign born—consistent with immigrant spatial incorporation. Finally, socioeconomic indicators are generally consistent with predictions of spatial assimilation. PMID:25589795

  8. Amplified North Atlantic warming in the late Pliocene by changes in Arctic gateways

    NASA Astrophysics Data System (ADS)

    Otto-Bliesner, Bette L.; Jahn, Alexandra; Feng, Ran; Brady, Esther C.; Hu, Aixue; Löfverström, Marcus

    2017-01-01

    Under previous reconstructions of late Pliocene boundary conditions, climate models have failed to reproduce the warm sea surface temperatures reconstructed in the North Atlantic. Using a reconstruction of mid-Piacenzian paleogeography that has the Bering Strait and Canadian Arctic Archipelago Straits closed, however, improves the simulation of the proxy-indicated warm sea surface temperatures in the North Atlantic in the Community Climate System Model. We find that the closure of these small Arctic gateways strengthens the Atlantic Meridional Overturning Circulation, by inhibiting freshwater transport from the Pacific to the Arctic Ocean and from the Arctic Ocean to the Labrador Sea, leading to warmer sea surface temperatures in the North Atlantic. This indicates that the state of the Arctic gateways may influence the sensitivity of the North Atlantic climate in complex ways, and better understanding of the state of these Arctic gateways for past time periods is needed.

  9. An overview of Grid portal technologies for the development of HMR science gateways

    NASA Astrophysics Data System (ADS)

    D'Agostino, D.

    2012-04-01

    Grid portals and related technologies represent an easy and transparent way for scientists to interact with Distributed Computing Infrastructures (DCIs) as the Grid and the Cloud. Many toolkits and frameworks are available, both commercial and open source, but there is a lack of best practices, customization methodologies and dedicated high-level service repositories that allow a fast development of specialized scientific gateways in Europe. Starting from the US TeraGrid-XSEDE experience, in this contribution the most interesting portal toolkits and related European projects are analyzed with the perspective to develop a science gateway for HMR community within the the Distributed Research Infrastructure for Hydrometeorology (DRIHM) project.

  10. The home gateway used in FTTH which can implement triple play

    NASA Astrophysics Data System (ADS)

    Ji, Wei; Yang, Hongliang; Liu, Yang; Liu, Yonghui; Cui, Wei

    2008-11-01

    The paper proposes the design of Home Gateway used in FTTH. On the customer's side, the Home Gateway finishes the optical signal receiving, provides three kinds of interfaces for the video, voice data, and attains the integration of the three services. PAS6301 chip achieves the control of voice, video and data services. Especially on the aspect of the video services, the HG system combines the advantages of IPTV and the DVB to offer a platform for receiving two signals. Users can use ordinary TV to receive both digital TV programs encoded by MPEG-2 and IPTV programs encoded by H.264.

  11. SCEC Earthworks: A TeraGrid Science Gateway

    NASA Astrophysics Data System (ADS)

    Francoeur, H.; Muench, J.; Okaya, D.; Maechling, P.; Deelman, E.; Mehta, G.

    2006-12-01

    SCEC Earthworks is a scientific gateway designed to provide community wide access to the TeraGrid. Earthworks provides its users with a portal based interface for easily running anelastic wave propagation (AWM) simulations. Using Gridsphere and several portlets developed as a collaborative effort with IRIS, Earthworks enables users to run simulations without any knowledge of the underlying workflow technology needed to utilize the TeraGrid. The workflow technology behind Earthworks has been developed as a collaborative effort between SCEC and the Information Sciences Institute (ISI). Earthworks uses a complex software stack to translate abstract workflows defined by the user into a series of jobs that run on a number of computational resources. These computational resources include a combination of servers provided by SCEC, USC High Performance Computing Center and NSF TeraGrid supercomputer facilities. Workflows are constructed after input from the user is passed via a Java based interface to the Earthworks backend, where a DAX (directed acyclic graph in XML) is generated. This DAX describes each step of the workflow including its inputs, outputs, and arguments, as well as the parent child relationships between each process. The DAX is then handed off to the Virtual Data System (VDS) and Pegasus provided by ISI, which translate it from an abstract workflow to a concrete workflow by filling in logical file and application names with their physical path and location. This newly created DAG (directed acyclic graph) is handed off to the Condor scheduler. The bottom part of the software stack is a Globus installation at each site the provides local transfer and resource management capabilities. Resources across different sites are transparently managed and tracked by VDS which allows greater flexibility in running the workflows. After a workflow is completed, products and metadata are registered with integrated data management tools. This allows for metadata querying

  12. Klimanavigator - Climate Navigator - Gateway to climate knowledge in Germany

    NASA Astrophysics Data System (ADS)

    Schuck-Zöller, Susanne

    2013-04-01

    Objective More than 50 German research institutions and networks are represented on www.klimanavigator.de, a common platform, where information about their work, and the latest findings from climate research and adaptation can be found. Thus Klimanavigator as a gateway to climate knowledge provides a information portal for those who have to respond to climate change. The internet portal gives an overview of the present state of research and is estimated as a decision support tool for appropriate mitigation and adaptation measures. Target Groups The portal collects the German climate research institutions to publish their scientific knowledge in a non-scientific language. Economists, policymakers, administration and the media are bound to find the names of scientific experts and institutions by an elaborated research tool. Methodology The chapter "Dossiers" is edited by the Klimanavigator-Coordinator CSC. It gathers information to a special issue looked upon from various points of view. Publications of outstanding German scientists are presented side by side, current knowledge is being synthesized, scientifically reviewed and disseminated. The latest news from climate and adaptation research is presented in an own chapter, dedicated to the press releases of the portal members. Via RSS-feed the press releases are collected from the different partner institutions. Thirdly, portraits of the member institutions, that are individually edited by themselves, draw a map of science in Germany and help to find appropriate cooperation partners. For the future further development is being planned. Common Management Klimanavigator is being managed by the partners in common. The main decisions concerning the concept and shape of the portal are made by the partners' assembly. An elected editorial committee decides about the content between the assemblies. The Climate Service Center (part of the Helmholtz-Zentrum Geesthacht) concentrates on facilitating the cooperation, and

  13. 77 FR 31032 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-24

    ... Institute on Aging; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee... clearly unwarranted invasion of personal privacy. Name of Committee: National Institute on Aging Special..., National Institute on Aging, Gateway Bldg., 2C212, 7201 Wisconsin Avenue Bethesda, MD 20814, 301-402-...

  14. Satellite Sensornet Gateway Technology Infusion Through Rapid Deployments for Environmental Sensing

    NASA Astrophysics Data System (ADS)

    Benzel, T.; Silva, F.; Deschon, A.; Ye, W.; Cho, Y.

    2008-12-01

    The Satellite Sensornet Gateway (SSG) is an ongoing ESTO Advanced Information Systems Technology project, at the University of Southern California. The major goal of SSG is to develop a turnkey solution for building environmental observation systems based on sensor networks. Our system has been developed through an iterative series of deployment-driven design, build, test, and revise which maximizes technology infusion to the earth scientist. We have designed a robust and flexible sensor network called Sensor Processing and Acquisition Network (SPAN). Our SPAN architecture emphasizes a modular and extensible design, such that core building blocks can be reused to develop different scientific observation systems. To support rapid deployment at remote locations, we employ satellite communications as the backhaul to relay in-situ sensor data to a central database. To easily support various science applications, we have developed a unified sensor integration framework that allows streamlined integration of different sensors to the system. Our system supports heterogeneous sets of sensors, from industry-grade products to research- specific prototypes. To ensure robust operation in harsh environments, we have developed mechanisms to monitor system status and recover from potential failures along with additional remote configuration and QA/QC functions. Here we briefly describe the deployments, the key science missions of the deployments and the role that the SSG technology played in each mission. We first deployed our SSG technology at the James Reserve in February 2007. In a joint deployment with the NEON project, SDSC, and UC Riverside, we set up a meteorological station, using a diverse set of sensors, with the objective of validating our basic technology components in the field. This system is still operational and streaming live sensor data. At Stunt Ranch, a UC Reserve near Malibu, CA, we partnered with UCLA biologist Phillip Rundel in order to study the drought

  15. The New Gateway, an Old Paradox: Immigrants and Involuntary Americans in North Carolina History Textbooks

    ERIC Educational Resources Information Center

    Hilburn, Jeremy; Fitchett, Paul G.

    2012-01-01

    The authors conducted a content analysis of North Carolina history textbooks to explore how the definition of immigration has changed over the last century. They also examined how immigrant groups and involuntary Americans have been portrayed throughout the state's history. Findings suggest that as a burgeoning gateway state for immigrants, North…

  16. 76 FR 60961 - Approval of Noise Compatibility Program; Kissimmee Gateway Airport, Kissimmee, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... Federal Aviation Administration Approval of Noise Compatibility Program; Kissimmee Gateway Airport... Administration (FAA) announces its findings on the Noise Compatibility Program Update (NCP) submitted by the City of Kissimmee under the provisions of 49 U.S.C. (the Aviation Safety and Noise Abatement...

  17. Out of the Depths Have I Cried: Aesthetic Opposition at the Gateway to Auschwitz

    ERIC Educational Resources Information Center

    Javore, Barbara B.

    2015-01-01

    Terezin, the gateway to Auschwitz, a town commandeered by the Nazis to serve as a "model" relocation camp to demonstrate the Third Reich's generosity and kindness toward the Jews, was an elaborate hoax. In an environment where truth was twisted beyond recognition, artists, writers, actors, and musicians used their work to revive the…

  18. What Factors Relate to Student Performance in Arkansas College Gateway Courses?

    ERIC Educational Resources Information Center

    Jenkins, Rick; Butler, Sharon

    2013-01-01

    In higher education in the state of Arkansas, two courses are considered to be gateway courses to obtaining a college degree--College Algebra and English Composition I. While students may obtain Certificates of Proficiency and Technical Certificates without taking these courses, few, if any, can earn an Associate's or Bachelor's degree without…

  19. Prioritizing Active Learning: An Exploration of Gateway Courses in Political Science

    ERIC Educational Resources Information Center

    Archer, Candace C.; Miller, Melissa K.

    2011-01-01

    Prior research in political science and other disciplines demonstrates the pedagogical and practical benefits of active learning. Less is known, however, about the extent to which active learning is used in political science classrooms. This study assesses the prioritization of active learning in "gateway" political science courses, paying…

  20. "TIS": An Intelligent Gateway Computer for Information and Modeling Networks. Overview.

    ERIC Educational Resources Information Center

    Hampel, Viktor E.; And Others

    TIS (Technology Information System) is being used at the Lawrence Livermore National Laboratory (LLNL) to develop software for Intelligent Gateway Computers (IGC) suitable for the prototyping of advanced, integrated information networks. Dedicated to information management, TIS leads the user to available information resources, on TIS or…

  1. RESTful M2M Gateway for Remote Wireless Monitoring for District Central Heating Networks

    PubMed Central

    Cheng, Bo; Wei, Zesan

    2014-01-01

    In recent years, the increased interest in energy conservation and environmental protection, combined with the development of modern communication and computer technology, has resulted in the replacement of distributed heating by central heating in urban areas. This paper proposes a Representational State Transfer (REST) Machine-to-Machine (M2M) gateway for wireless remote monitoring for a district central heating network. In particular, we focus on the resource-oriented RESTful M2M gateway architecture, and present an uniform devices abstraction approach based on Open Service Gateway Initiative (OSGi) technology, and implement the resource mapping mechanism between resource address mapping mechanism between RESTful resources and the physical sensor devices, and present the buffer queue combined with polling method to implement the data scheduling and Quality of Service (QoS) guarantee, and also give the RESTful M2M gateway open service Application Programming Interface (API) set. The performance has been measured and analyzed. Finally, the conclusions and future work are presented. PMID:25436650

  2. Communicating Astronomy with the Public (Youth) as the Gateway to Development

    NASA Astrophysics Data System (ADS)

    Crabtree, Dennis R.

    2015-03-01

    Astronomy has a unique ability to excite and stimulate the curiosity of children. Because of this, society can use astronomy as a gateway to lead children on a path towards future learning of science and technology, and potentially to careers in these areas.

  3. GATEWAY Demonstrations: Trial Demonstration of Area Lighting Retrofit, Yuma Border Patrol, Yuma, Arizona

    SciTech Connect

    Wilkerson, A. M.; McCullough, J. J.

    2014-12-31

    Along the Yuma Sector Border Patrol Area in Yuma, Arizona, the GATEWAY program conducted a trial demonstration in which the incumbent quartz metal halide area lighting was replaced with LED at three pole locations at the Yuma Sector Border Patrol Area in Yuma, Arizona. The retrofit was documented to better understand LED technology performance in high-temperature environments.

  4. A Squandered Resource: The Divestment of Mexican Parental Involvement in a New Gateway State

    ERIC Educational Resources Information Center

    Petrone, Eleanor

    2016-01-01

    Parental involvement plays an important role in the academic success of children. Schools in new gateway states where there has not been a longstanding tradition of immigration often lack the cultural knowledge and linguistic resources necessary to serve immigrant youth and their families effectively. By examining the experiences of Mexican…

  5. Student Learning in Linear Algebra: The Gateways To Advance Mathematical Thinking Project.

    ERIC Educational Resources Information Center

    Manes, Michelle

    This document provides a preliminary report of the study Gateways To Advance Mathematical Thinking (GAMT) run by Educational Development Center, Inc. (EDC). The study was designed to see what types of reasoning students who have recently completed a linear algebra course apply to problems in algebraic thinking. Student interviews were used as the…

  6. EAC and the Development of National and European Gateways to Archives

    ERIC Educational Resources Information Center

    Ottosson, Per-Gunnar

    2005-01-01

    In the development of gateways to archives there are two different approaches, one focusing on the descriptions of the material and the other on the creators. Search and retrieval with precision and quality require controlled access points and name authority control. National registries of private archives have a long tradition in implementing the…

  7. From the Adam Smith Institute to the Zapatistas: An Internet Gateway to all Development Knowledge.

    ERIC Educational Resources Information Center

    Wilks, Alex

    2002-01-01

    Examines the World Bank Internet initiative, the Development Gateway. Describes the importance of the Bank as a knowledge bank and the threats posed by the Internet to its near monopoly of development thinking. Argues that the initiative reveals biases and misunderstandings in the World Bank's approach to knowledge for development. (CAJ)

  8. Construction of adenovirus vectors encoding the lumican gene by gateway recombinant cloning technology

    PubMed Central

    Wang, Gui-Fang; Qi, Bing; Tu, Lei-Lei; Liu, Lian; Yu, Guo-Cheng; Zhong, Jing-Xiang

    2016-01-01

    AIM To construct adenovirus vectors of lumican gene by gateway recombinant cloning technology to further understand the role of lumican gene in myopia. METHODS Gateway recombinant cloning technology was used to construct adenovirus vectors. The wild-type (wt) and mutant (mut) forms of the lumican gene were synthesized and amplified by polymerase chain reaction (PCR). The lumican cDNA fragments were purified and ligated into the adenovirus shuttle vector pDown-multiple cloning site (MCS)-/internal ribozyme entry site (IRES)/enhanced green fluorescent protein (EGFP). Then the desired DNA fragments were integrated into the destination vector pAV.Des1d yielding the final expression constructs pAV.Ex1d-cytomegalovirus (CMV)>wt-lumican/IRES/EGFP and pAV.Ex1d-CMV>mut-lumican/IRES /EGFP, respectively. RESULTS The adenovirus plasmids pAV.Ex1d-CMV>wt-lumican/IRES/EGFP and pAV.Ex1d-CMV>mut-lumican/IRES/EGFP were successfully constructed by gateway recombinant cloning technology. Positive clones identified by PCR and sequencing were selected and packaged into recombinant adenovirus in HEK293 cells. CONCLUSION We construct adenovirus vectors containing the lumican gene by gateway recombinant cloning technology, which provides a basis for investigating the role of lumican gene in the pathogenesis of high myopia. PMID:27672590

  9. Toolbox of Activities to Support Students in a Physics Gateway Course

    ERIC Educational Resources Information Center

    Kalman, Calvin S.; Rohar, Shelley

    2010-01-01

    This paper presents a set of activities, which scaffolds students to succeed in the standard Physics gateway course. The set of instructional activities that were designed included four distinct components: reflective writing, collaborative groups, critiques, and an essay question on the examination. Each activity was designed to lead into and…

  10. 77 FR 47621 - Appalachian Gateway Project; Notice of Availability of Draft General Conformity Analysis

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-09

    ... Conformity Analysis In accordance with the National Environmental Policy Act of 1969, the Clean Air Act and... prepared this draft General Conformity Determination (GCD) for the Appalachian Gateway Project (Project) to... the Project will achieve conformity in Pennsylvania with the use of Pennsylvania Department...

  11. Designing an effective gateway for documentation search through a WWW server

    SciTech Connect

    Nguyen, V.

    1995-11-01

    Lookup, a NERSC`s utility, searches several documentation databases to find exact as well as approximate matches for the user`s search term. However, it is only available for those who run it directly on NERSC`s machines. To provide a wider access to a large audience, I developed a gateway which handles information requests and returns the appropriated documents.

  12. LIPID MAPS-Nature Lipidomics Gateway: An Online Resource for Students and Educators Interested in Lipids

    PubMed Central

    Sud, Manish; Fahy, Eoin; Cotter, Dawn; Dennis, Edward A.; Subramaniam, Shankar

    2012-01-01

    The LIPID MAPS-Nature Lipidomics Gateway is a free, comprehensive online resource providing tutorials and instructional material, experimental data for lipids and genes along with protocols and standards, databases of lipid structures and lipid-associated genes or proteins, and a variety of lipidomics tools. PMID:24764601

  13. LIPID MAPS-Nature Lipidomics Gateway: An Online Resource for Students and Educators Interested in Lipids.

    PubMed

    Sud, Manish; Fahy, Eoin; Cotter, Dawn; Dennis, Edward A; Subramaniam, Shankar

    2012-01-10

    The LIPID MAPS-Nature Lipidomics Gateway is a free, comprehensive online resource providing tutorials and instructional material, experimental data for lipids and genes along with protocols and standards, databases of lipid structures and lipid-associated genes or proteins, and a variety of lipidomics tools.

  14. 75 FR 70349 - Blackwell Northern Gateway Railroad Company-Lease Renewal Exemption-Oklahoma Department of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-17

    ... Surface Transportation Board Blackwell Northern Gateway Railroad Company-Lease Renewal Exemption-Oklahoma... Blackwell Line extending from milepost 18.32, near Hunnewell, Kan., on the Oklahoma/Kansas border, to.../Oklahoma border, and from milepost 126.45 to milepost 125.0 in Blackwell. \\1\\ BNGR states that...

  15. An Assessment of the Adult Learners' Needs at Gateway Community-Technical College.

    ERIC Educational Resources Information Center

    Luna, Wilson

    A study was conducted to assess the needs of adult learners at Gateway Community-Technical College (GCTC), in North Haven, Connecticut. An extended literature review resulted the choice of the three-part Adult Learner Needs Assessment Survey (ALNAS). In spring 1993, the ALNAS was administered to adult learners in classes at GCTC, resulting in 400…

  16. RESTful M2M gateway for remote wireless monitoring for district central heating networks.

    PubMed

    Cheng, Bo; Wei, Zesan

    2014-11-27

    In recent years, the increased interest in energy conservation and environmental protection, combined with the development of modern communication and computer technology, has resulted in the replacement of distributed heating by central heating in urban areas. This paper proposes a Representational State Transfer (REST) Machine-to-Machine (M2M) gateway for wireless remote monitoring for a district central heating network. In particular, we focus on the resource-oriented RESTful M2M gateway architecture, and present an uniform devices abstraction approach based on Open Service Gateway Initiative (OSGi) technology, and implement the resource mapping mechanism between resource address mapping mechanism between RESTful resources and the physical sensor devices, and present the buffer queue combined with polling method to implement the data scheduling and Quality of Service (QoS) guarantee, and also give the RESTful M2M gateway open service Application Programming Interface (API) set. The performance has been measured and analyzed. Finally, the conclusions and future work are presented.

  17. The Divine Dreams of a Sample of South African Children: The Gateway to Their Spirituality

    ERIC Educational Resources Information Center

    Potgieter, Ferdinand J.; van der Walt, Johannes L.; Wolhuter, Charl C.

    2009-01-01

    As part of a research project on religion, spirituality and education, the authors attended to the role that children's divine dreams could play in religious education (RE). They contend that such dreams can indeed be used by RE teachers as the gateway to understanding the spirituality of their learners. They defend their claim by firstly…

  18. Resource Sharing through Integration of an Intelligent Gateway and Library Support Software.

    ERIC Educational Resources Information Center

    Burton, Hilary D.; And Others

    1986-01-01

    Integration of an intelligent gateway system with a commercial, online library support system to produce an integrated bibliographic information system is undergoing prototype testing for the Department of Defense libraries. The objective is to create an integrated system to promote resource sharing in a distributed environment. Five sources are…

  19. Perceived Connections between Anti-Social Gateway Behaviors and School Bullying and Culture

    ERIC Educational Resources Information Center

    Grell, Brett Stanley; Meyer, Richard C.

    2016-01-01

    The purpose of this study was to examine and compare opinions of 8th and 9th grade teachers and students regarding the prevalence of anti-social/gateway behaviors in their classrooms, the perceived connection between these behaviors and more traditional forms of bullying, and the potential impact of school-wide anti-bullying programs specifically…

  20. EAARL coastal topography-Gateway National Recreation Area, New Jersey and New York, 2009

    USGS Publications Warehouse

    Nayegandhi, Amar; Vivekanandan, Saisudha; Brock, John C.; Stevens, Sara; Wright, C. Wayne; Bonisteel, Jamie M.; Nagle, David B.; Yates, Xan; Klipp, Emily S.

    2010-01-01

    This DVD contains lidar-derived bare-earth (BE) and first-surface (FS) topography GIS datasets of a portion of the Gateway National Recreation Area in New Jersey and New York. These datasets were acquired July 8-9, 2009.

  1. An Evaluation of a Gateway System for Automated Online Database Selection.

    ERIC Educational Resources Information Center

    Hu, Chengren

    This paper describes a study that was undertaken at the University of Illinois at Urbana-Champaign to compare the databases selected by 75 inexperienced student online searchers aided by an existing gateway system--INFOMASTER, a version of EASYNET--with databases selected manually by four experienced searchers who were reference librarians from…

  2. High School Teachers' Perceptions of Teaching Civics to Immigrant Students in a New Gateway State

    ERIC Educational Resources Information Center

    Hilburn, Jeremy Dale

    2012-01-01

    This qualitative study examines Civics teachers' perceptions of working with immigrant students in a new gateway state. By analyzing collective case studies of six teachers in central North Carolina, from different types of schools and with different professional backgrounds, this study is positioned to make recommendations for social studies…

  3. Constructing Web Subject Gateways Using Dublin Core, the Resource Description Framework and Topic Maps

    ERIC Educational Resources Information Center

    Tramullas, Jesus; Garrido, Piedad

    2006-01-01

    Introduction: Specialised subject gateways have become an essential tool for locating and accessing digital information resources, with the added value of organisation and previous evaluation catering for the needs of the varying communities using these. Within the framework of a research project on the subject, a software tool has been developed…

  4. ADDOSS: Autonomously Deployed Deep-ocean Seismic System - Communications Gateway for Ocean Observatories

    NASA Astrophysics Data System (ADS)

    Laske, Gabi; Berger, Jon; Orcutt, John; Babcock, Jeff

    2014-05-01

    We describe an autonomously deployable, communications gateway designed to provide long-term and near real-time data from ocean observatories. The key features of this new system are its abilities to telemeter sensor data from the seafloor to shore without cables or moorings, and to be deployed without a ship, thereby greatly reducing life-cycle costs. The free-floating surface communications gateway utilizes a Liquid Robotics wave glider comprising a surfboard-sized float towed by a tethered, submerged glider, which converts wave motion into thrust. For navigation, the wave glider is equipped with a small computer, a GPS receiver, a rudder, solar panels and batteries, and an Iridium satellite modem. Acoustic communications connect the subsea instruments and the surface gateway while communications between the gateway and land are provided by the Iridium satellite constellation. Wave gliders have demonstrated trans-oceanic range and long-term station keeping capabilities. The acoustics communications package is mounted in a shallow tow body which utilizes a WHOI micro modem and a Benthos low frequency, directional transducer. A matching modem and transducer is mounted on the ocean bottom package. Tests of the surface gateway in 4350 m of water demonstrated an acoustic efficiency of approximately 396 bits/J. For example, it has the ability to send 4 channels of compressed, 1 sample per second data from the ocean bottom to the gateway with an average power draw of approximately 0.15 W and a latency of less than 3 minutes. This gateway is used to send near real-time data from a broadband ocean bottom seismic observatory, first during short week-to-months long test deployments but will ultimately be designed for a two-year operational life. Such data from presently unobserved oceanic areas are critical for both national and international agencies in monitoring and characterizing earthquakes, tsunamis, and nuclear explosions. We present initial results from a two short

  5. Effect of composite surface treatment and aging on the bond strength between a core build-up composite and a luting agent

    PubMed Central

    COTES, Caroline; CARDOSO, Mayra; de MELO, Renata Marques; VALANDRO, Luiz Felipe; BOTTINO, Marco Antonio

    2015-01-01

    Objective The purpose of this study was to assess the influence of conditioning methods and thermocycling on the bond strength between composite core and resin cement. Material and Methods Eighty blocks (8×8×4 mm) were prepared with core build-up composite. The cementation surface was roughened with 120-grit carbide paper and the blocks were thermocycled (5,000 cycles, between 5°C and 55°C, with a 30 s dwell time in each bath). A layer of temporary luting agent was applied. After 24 h, the layer was removed, and the blocks were divided into five groups, according to surface treatment: (NT) No treatment (control); (SP) Grinding with 120-grit carbide paper; (AC) Etching with 37% phosphoric acid; (SC) Sandblasting with 30 mm SiO2 particles, silane application; (AO) Sandblasting with 50 mm Al2O3 particles, silane application. Two composite blocks were cemented to each other (n=8) and sectioned into sticks. Half of the specimens from each block were immediately tested for microtensile bond strength (µTBS), while the other half was subjected to storage for 6 months, thermocycling (12,000 cycles, between 5°C and 55°C, with a dwell time of 30 s in each bath) and µTBS test in a mechanical testing machine. Bond strength data were analyzed by repeated measures two-way ANOVA and Tukey test (α=0.05). Results The µTBS was significantly affected by surface treatment (p=0.007) and thermocycling (p=0.000). Before aging, the SP group presented higher bond strength when compared to NT and AC groups, whereas all the other groups were statistically similar. After aging, all the groups were statistically similar. SP submitted to thermocycling showed lower bond strength than SP without thermocycling. Conclusion Core composites should be roughened with a diamond bur before the luting process. Thermocycling tends to reduce the bond strength between composite and resin cement. PMID:25760269

  6. Integrated DoD Voice and Data Networks and Ground Packet Radio Technology Volume 3. Topological Gateway Placement Strategies

    DTIC Science & Technology

    1977-03-01

    experience , e.g., hierarchical adaptive routing policies are preferred over single level fixed routing policies. For other issues, the answers are not so...the constraint after Step 6. In all of our design experiments , only a small amount of internet gateway-half to gateway-half requirement is routed on...ANALYSIS CORPORATION 7.6 EXPERIMENTAL RESULTS The procedures presented in Section 7.5 have been implemented on a PDP-10. Numerous experiments were

  7. GATEWAY Demonstrations: LED System Performance in a Trial Installation--One Year Later, Yuma Border Patrol, Yuma, Arizona

    SciTech Connect

    Wilkerson, A. M.; Davis, R. G.

    2015-04-01

    Along the Yuma Sector Border Patrol Area in Yuma, Arizona, the GATEWAY program conducted a trial demonstration in which the incumbent quartz metal halide area lighting was replaced with LED at three pole locations at the Yuma Sector Border Patrol Area in Yuma, Arizona. The retrofit was documented to better understand LED technology performance in high-temperature environments. This report follows the GATEWAY Yuma Phase 1.0 Report and reflects LED system results documented one year after the demonstration began.

  8. Age of Inhalant First Time Use and Its Association to the Use of Other Drugs

    ERIC Educational Resources Information Center

    Ding, Kele; Chang, G. Andy; Southerland, Ron

    2009-01-01

    Inhalants are the 4th most commonly abused drugs after alcohol, tobacco, and marijuana. Although inhalants are often referred as Gateway Drugs this hypothesis is less examined. Using the 2003 National Survey on Drug Use and Health data, age of first time inhalant use was compared with the age of onset of other drugs among 6466 inhalant users who…

  9. Environmental Survey and Assessment of Gateway Army Ammunition Plant

    DTIC Science & Technology

    1982-06-01

    which can cause histoplasmosis . SECURITY Cl-ASSIFICATION OF THIS PAGE./"an Dat& Entored) GAAPFINAL. I/SUMMARY. 1 6/3/82 o01314 SUMMARY This report...and Recovery Act of 1976; and the presence of a biological health hazard, which can cause histoplasmosis . Spills and leaks of hydraulic fluid and oil...3.5.2 Spills 3-38 3.5.3 Histoplasmosis Hazard 3-39 3.6 AIR SAMPLING 3-39 4.0 INSTALLATION ASSESSMENT 4-1 4.1 MAIN MANUFACTURING BUILDING 4-3 4.2

  10. The scientific consensus on climate change as a gateway belief: experimental evidence.

    PubMed

    van der Linden, Sander L; Leiserowitz, Anthony A; Feinberg, Geoffrey D; Maibach, Edward W

    2015-01-01

    There is currently widespread public misunderstanding about the degree of scientific consensus on human-caused climate change, both in the US as well as internationally. Moreover, previous research has identified important associations between public perceptions of the scientific consensus, belief in climate change and support for climate policy. This paper extends this line of research by advancing and providing experimental evidence for a "gateway belief model" (GBM). Using national data (N = 1104) from a consensus-message experiment, we find that increasing public perceptions of the scientific consensus is significantly and causally associated with an increase in the belief that climate change is happening, human-caused and a worrisome threat. In turn, changes in these key beliefs are predictive of increased support for public action. In short, we find that perceived scientific agreement is an important gateway belief, ultimately influencing public responses to climate change.

  11. Is N-sulfation just a gateway modification during heparan sulfate biosynthesis?

    PubMed

    Raman, Karthik; Nguyen, Thao Kim Nu; Kuberan, Balagurunathan

    2011-11-04

    Several biologically important growth factor-heparan sulfate (HS) interactions are regulated by HS sulfation patterns. However, the biogenesis of these combinatorial sulfation patterns is largely unknown. N-Deacetylase/N-sulfotrasferase (NDST) converts N-acetyl-d-glucosamine residues to N-sulfo-d-glucosamine residues. This enzyme is suggested to be a gateway enzyme because N-sulfation dictates the final HS sulfation pattern. It is known that O-sulfation blocks C5-epimerase, which acts immediately after NDST action. However, it is still unknown whether O-sulfation inhibits NDST action in a similar manner. In this article we radically change conventional assumptions regarding HS biosynthesis by providing in vitro evidence that N-sulfation is not necessarily just a gateway modification during HS biosynthesis.

  12. The Scientific Consensus on Climate Change as a Gateway Belief: Experimental Evidence

    PubMed Central

    van der Linden, Sander L.; Leiserowitz, Anthony A.; Feinberg, Geoffrey D.; Maibach, Edward W.

    2015-01-01

    There is currently widespread public misunderstanding about the degree of scientific consensus on human-caused climate change, both in the US as well as internationally. Moreover, previous research has identified important associations between public perceptions of the scientific consensus, belief in climate change and support for climate policy. This paper extends this line of research by advancing and providing experimental evidence for a “gateway belief model” (GBM). Using national data (N = 1104) from a consensus-message experiment, we find that increasing public perceptions of the scientific consensus is significantly and causally associated with an increase in the belief that climate change is happening, human-caused and a worrisome threat. In turn, changes in these key beliefs are predictive of increased support for public action. In short, we find that perceived scientific agreement is an important gateway belief, ultimately influencing public responses to climate change. PMID:25714347

  13. Social class culture cycles: how three gateway contexts shape selves and fuel inequality.

    PubMed

    Stephens, Nicole M; Markus, Hazel Rose; Phillips, L Taylor

    2014-01-01

    America's unprecedented levels of inequality have far-reaching negative consequences for society as a whole. Although differential access to resources contributes to inequality, the current review illuminates how ongoing participation in different social class contexts also gives rise to culture-specific selves and patterns of thinking, feeling, and acting. We integrate a growing body of interdisciplinary research to reveal how social class culture cycles operate over the course of the lifespan and through critical gateway contexts, including homes, schools, and workplaces. We first document how each of these contexts socializes social class cultural differences. Then, we demonstrate how these gateway institutions, which could provide access to upward social mobility, are structured according to middle-class ways of being a self and thus can fuel and perpetuate inequality. We conclude with a discussion of intervention opportunities that can reduce inequality by taking into account the contextual responsiveness of the self.

  14. Production of Myxoma virus gateway entry and expression libraries and validation of viral protein expression.

    PubMed

    Smallwood, Sherin E; Rahman, Masmudur M; Werden, Steven J; Martino, Maria Fernanda; McFadden, Grant

    2011-05-01

    Invitrogen's Gateway technology is a recombination-based cloning method that allows for rapid transfer of numerous open reading frames (ORFs) into multiple plasmid vectors, making it useful for diverse high-throughput applications. Gateway technology has been utilized to create an ORF library for Myxoma virus (MYXV), a member of the Poxviridae family of DNA viruses. MYXV is the prototype virus for the genus Leporipoxvirus, and is pathogenic only in European rabbits. MYXV replicates exclusively in the host cell cytoplasm, and its genome encodes 171 ORFs. A number of these ORFs encode proteins that interfere with or modulate host defense mechanisms, particularly the inflammatory responses. Furthermore, MYXV is able to productively infect a variety of human cancer cell lines and is being developed as an oncolytic virus for treating human cancers. MYXV is therefore an excellent model for studying poxvirus biology, pathogenesis, and host tropism, and a good candidate for ORFeome development.

  15. Wide-area Gigabit networking: Los Alamos HIPPI-SONET Gateway

    SciTech Connect

    St. John, W.B.; DuBois, D.H.

    1995-05-01

    This paper describes a HIPPI-SONET Gateway which has been designed by members of the Computer Network Engineering Group at Los Alamos National Laboratory. The Gateway has been used in the CASA Gigabit Testbed at Caltech, Los Alamos National Laboratory, and the San Diego Supercomputer Center to provide communications between the sites. This paper will also make some qualitative statements as to lessons learned during the deployment and maintenance of this wide area network. We report record throughput for transmission of data across a wide area network. We have sustained data rates using the TCP/IP protocol of 550 Mbits/second and the rate of 792 Mbits/second for raw HIPPI data transfer over the 2,000 kilometers from the San Diego Supercomputer Center to the Los Alamos National Laboratory.

  16. Onset of Antarctic Circumpolar Current 30 million years ago as Tasmanian Gateway aligned with westerlies.

    PubMed

    Scher, Howie D; Whittaker, Joanne M; Williams, Simon E; Latimer, Jennifer C; Kordesch, Wendy E C; Delaney, Margaret L

    2015-07-30

    Earth's mightiest ocean current, the Antarctic Circumpolar Current (ACC), regulates the exchange of heat and carbon between the ocean and the atmosphere, and influences vertical ocean structure, deep-water production and the global distribution of nutrients and chemical tracers. The eastward-flowing ACC occupies a unique circumglobal pathway in the Southern Ocean that was enabled by the tectonic opening of key oceanic gateways during the break-up of Gondwana (for example, by the opening of the Tasmanian Gateway, which connects the Indian and Pacific oceans). Although the ACC is a key component of Earth's present and past climate system, the timing of the appearance of diagnostic features of the ACC (for example, low zonal gradients in water-mass tracer fields) is poorly known and represents a fundamental gap in our understanding of Earth history. Here we show, using geophysically determined positions of continent-ocean boundaries, that the deep Tasmanian Gateway opened 33.5 ± 1.5 million years ago (the errors indicate uncertainty in the boundary positions). Following this opening, sediments from Indian and Pacific cores recorded Pacific-type neodymium isotope ratios, revealing deep westward flow equivalent to the present-day Antarctic Slope Current. We observe onset of the ACC at around 30 million years ago, when Southern Ocean neodymium isotopes record a permanent shift to modern Indian-Atlantic ratios. Our reconstructions of ocean circulation show that massive reorganization and homogenization of Southern Ocean water masses coincided with migration of the northern margin of the Tasmanian Gateway into the mid-latitude westerly wind band, which we reconstruct at 64° S, near to the northern margin. Onset of the ACC about 30 million years ago coincided with major changes in global ocean circulation and probably contributed to the lower atmospheric carbon dioxide levels that appear after this time.

  17. Onset of Antarctic Circumpolar Current 30 million years ago as Tasmanian Gateway aligned with westerlies

    NASA Astrophysics Data System (ADS)

    Scher, Howie D.; Whittaker, Joanne M.; Williams, Simon E.; Latimer, Jennifer C.; Kordesch, Wendy E. C.; Delaney, Margaret L.

    2015-07-01

    Earth's mightiest ocean current, the Antarctic Circumpolar Current (ACC), regulates the exchange of heat and carbon between the ocean and the atmosphere, and influences vertical ocean structure, deep-water production and the global distribution of nutrients and chemical tracers. The eastward-flowing ACC occupies a unique circumglobal pathway in the Southern Ocean that was enabled by the tectonic opening of key oceanic gateways during the break-up of Gondwana (for example, by the opening of the Tasmanian Gateway, which connects the Indian and Pacific oceans). Although the ACC is a key component of Earth's present and past climate system, the timing of the appearance of diagnostic features of the ACC (for example, low zonal gradients in water-mass tracer fields) is poorly known and represents a fundamental gap in our understanding of Earth history. Here we show, using geophysically determined positions of continent-ocean boundaries, that the deep Tasmanian Gateway opened 33.5 +/- 1.5 million years ago (the errors indicate uncertainty in the boundary positions). Following this opening, sediments from Indian and Pacific cores recorded Pacific-type neodymium isotope ratios, revealing deep westward flow equivalent to the present-day Antarctic Slope Current. We observe onset of the ACC at around 30 million years ago, when Southern Ocean neodymium isotopes record a permanent shift to modern Indian-Atlantic ratios. Our reconstructions of ocean circulation show that massive reorganization and homogenization of Southern Ocean water masses coincided with migration of the northern margin of the Tasmanian Gateway into the mid-latitude westerly wind band, which we reconstruct at 64° S, near to the northern margin. Onset of the ACC about 30 million years ago coincided with major changes in global ocean circulation and probably contributed to the lower atmospheric carbon dioxide levels that appear after this time.

  18. Competitive Swarm Optimizer Based Gateway Deployment Algorithm in Cyber-Physical Systems

    PubMed Central

    Huang, Shuqiang; Tao, Ming

    2017-01-01

    Wireless sensor network topology optimization is a highly important issue, and topology control through node selection can improve the efficiency of data forwarding, while saving energy and prolonging lifetime of the network. To address the problem of connecting a wireless sensor network to the Internet in cyber-physical systems, here we propose a geometric gateway deployment based on a competitive swarm optimizer algorithm. The particle swarm optimization (PSO) algorithm has a continuous search feature in the solution space, which makes it suitable for finding the geometric center of gateway deployment; however, its search mechanism is limited to the individual optimum (pbest) and the population optimum (gbest); thus, it easily falls into local optima. In order to improve the particle search mechanism and enhance the search efficiency of the algorithm, we introduce a new competitive swarm optimizer (CSO) algorithm. The CSO search algorithm is based on an inter-particle competition mechanism and can effectively avoid trapping of the population falling into a local optimum. With the improvement of an adaptive opposition-based search and its ability to dynamically parameter adjustments, this algorithm can maintain the diversity of the entire swarm to solve geometric K-center gateway deployment problems. The simulation results show that this CSO algorithm has a good global explorative ability as well as convergence speed and can improve the network quality of service (QoS) level of cyber-physical systems by obtaining a minimum network coverage radius. We also find that the CSO algorithm is more stable, robust and effective in solving the problem of geometric gateway deployment as compared to the PSO or Kmedoids algorithms. PMID:28117735

  19. BioGateway: a semantic systems biology tool for the life sciences

    PubMed Central

    Antezana, Erick; Blondé, Ward; Egaña, Mikel; Rutherford, Alistair; Stevens, Robert; De Baets, Bernard; Mironov, Vladimir; Kuiper, Martin

    2009-01-01

    Background Life scientists need help in coping with the plethora of fast growing and scattered knowledge resources. Ideally, this knowledge should be integrated in a form that allows them to pose complex questions that address the properties of biological systems, independently from the origin of the knowledge. Semantic Web technologies prove to be well suited for knowledge integration, knowledge production (hypothesis formulation), knowledge querying and knowledge maintenance. Results We implemented a semantically integrated resource named BioGateway, comprising the entire set of the OBO foundry candidate ontologies, the GO annotation files, the SWISS-PROT protein set, the NCBI taxonomy and several in-house ontologies. BioGateway provides a single entry point to query these resources through SPARQL. It constitutes a key component for a Semantic Systems Biology approach to generate new hypotheses concerning systems properties. In the course of developing BioGateway, we faced challenges that are common to other projects that involve large datasets in diverse representations. We present a detailed analysis of the obstacles that had to be overcome in creating BioGateway. We demonstrate the potential of a comprehensive application of Semantic Web technologies to global biomedical data. Conclusion The time is ripe for launching a community effort aimed at a wider acceptance and application of Semantic Web technologies in the life sciences. We call for the creation of a forum that strives to implement a truly semantic life science foundation for Semantic Systems Biology. Access to the system and supplementary information (such as a listing of the data sources in RDF, and sample queries) can be found at . PMID:19796395

  20. The Lunar L1 Gateway Concept: Supporting Future Major Space Science Facilities

    NASA Technical Reports Server (NTRS)

    Thronson, H.; Geffre, J.; Prusha, S.; Caroff, L.; Weisbin, C.

    2004-01-01

    We report here on a series of ongoing studies to evaluate alternative architectures for future space science facilities and how robots, humans, and autonomous systems might be optimally used to support them. This presentation outlines one scenario -- a "Gateway" at the Earth-Moon L1 point for supporting multiple options beyond Low Earth Orbit -- plus our process for evaluating human/robotic activities to construct telescopes.

  1. Competitive Swarm Optimizer Based Gateway Deployment Algorithm in Cyber-Physical Systems.

    PubMed

    Huang, Shuqiang; Tao, Ming

    2017-01-22

    Wireless sensor network topology optimization is a highly important issue, and topology control through node selection can improve the efficiency of data forwarding, while saving energy and prolonging lifetime of the network. To address the problem of connecting a wireless sensor network to the Internet in cyber-physical systems, here we propose a geometric gateway deployment based on a competitive swarm optimizer algorithm. The particle swarm optimization (PSO) algorithm has a continuous search feature in the solution space, which makes it suitable for finding the geometric center of gateway deployment; however, its search mechanism is limited to the individual optimum (pbest) and the population optimum (gbest); thus, it easily falls into local optima. In order to improve the particle search mechanism and enhance the search efficiency of the algorithm, we introduce a new competitive swarm optimizer (CSO) algorithm. The CSO search algorithm is based on an inter-particle competition mechanism and can effectively avoid trapping of the population falling into a local optimum. With the improvement of an adaptive opposition-based search and its ability to dynamically parameter adjustments, this algorithm can maintain the diversity of the entire swarm to solve geometric K-center gateway deployment problems. The simulation results show that this CSO algorithm has a good global explorative ability as well as convergence speed and can improve the network quality of service (QoS) level of cyber-physical systems by obtaining a minimum network coverage radius. We also find that the CSO algorithm is more stable, robust and effective in solving the problem of geometric gateway deployment as compared to the PSO or Kmedoids algorithms.

  2. Baker-Barry Tunnel Lighting: Evaluation of a Potential GATEWAY Demonstrations Project

    SciTech Connect

    Tuenge, Jason R.

    2011-06-01

    The U.S. Department of Energy (DOE) is evaluating the Baker-Barry Tunnel as a potential GATEWAY Demonstrations project for deployment of solid-state lighting (SSL) technology. The National Park Service (NPS) views this project as a possible proving ground and template for implementation of light-emitting diode (LED) luminaires in other NPS tunnels, thereby expanding the estimated 40% energy savings from 132 MWh/yr for this tunnel to a much larger figure national

  3. Reconstructing the lost eastern Tethys Ocean Basin: Convergence history of the SE Asian margin and marine gateways

    NASA Astrophysics Data System (ADS)

    Heine, Christian; Müller, R. Dietmar; Gaina, Carmen

    Plate tectonic reconstructions for the late Mesozoic-Cenozoic evolution of the eastern Tethyan Ocean Basin, separating eastern Gondwanaland from Proto-Southeast Asia, are usually based on geological data gathered from the different tectonic blocks accreted to Southeast Asia. However, this approach only provides few constraints on the reconstruction of the eastern Tethys Ocean and the drift path of various terranes. We have used marine magnetic anomalies in the Argo and Gascoyne Abyssal Plains off the Australian Northwest Shelf, jointly with published geological data, to reconstruct the seafloor spreading history and plate tectonic evolution of the eastern Tethys and Proto-Indian Ocean basins for the time between 160 Ma and the present. Based on the assumption of symmetrical seafloor spreading and a hotspot-track-based plate reference frame, we have created a relative and absolute plate motion model and a series of oceanic paleo-age grids that show the evolution of Tethyan mid-ocean ridges and the convergence history along the southeast Asian margin through time. A thermal boundary layer model for oceanic lithosphere is used to compute approximate paleo-depths to oceanic basement to predict the opening and closing of oceanic gateways. The proposed model not only provides improved boundary conditions for paleoclimate reconstructions and modelling of oceanic currents through time, but also for understanding stress changes in the overriding plate and the formation of new accretionary crust along the Southeast Asian margin, driven by changing subduction parameters like hinge rollback and slab dip.

  4. A simple Gateway-assisted construction system of TALEN genes for plant genome editing

    PubMed Central

    Kusano, Hiroaki; Onodera, Hitomi; Kihira, Miho; Aoki, Hiromi; Matsuzaki, Hikaru; Shimada, Hiroaki

    2016-01-01

    TALEN is an artificial nuclease being applied for sequence-specific genome editing. For the plant genome editing, a pair of TALEN genes is expressed in the cells, and a binary plasmid for Agrobacterium-mediated transformation should be assembled. We developed a novel procedure using the Gateway-assisted plasmids, named Emerald–Gateway TALEN system. We constructed entry vectors, pPlat plasmids, for construction of a desired TALEN gene using Platinum Gate TALEN kit. We also created destination plasmid, pDual35SGw1301, which allowed two TALEN genes to both DNA strands to recruit using Gateway technology. Resultant TALEN genes were evaluated by the single-strand annealing (SSA) assay in E. coli cells. By this assay, the TALENs recognized the corresponding targets in the divided luciferase gene, and induced a specific recombination to generate an active luciferase gene. Using the TALEN genes constructed, we created a transformant potato cells in which a site-specific mutation occurred at the target site of the GBSS gene. This suggested that our system worked effectively and was applicable as a convenient tool for the plant genome editing. PMID:27452606

  5. Energy-aware Gateway Selection for increasing the lifetime of Wireless Body Area Sensor Networks.

    PubMed

    Bayilmis, Cuneyt; Younis, Mohamed

    2012-06-01

    A Wireless Body Area Sensor Network (WBASN) is composed of a set of sensor nodes, placed on, near or within a human body. WBASNs opt to continuously monitor the health conditions of individuals under medical risk, e.g., elders and chronically ill people, without keeping them in a hospital or restraining their motion. A WBASN needs to stay connected to local or wide area networks using wireless technologies in order to send sensor readings to a medical center. The WBASN nodes are implanted within the human body and would thus have limited energy supply. Since the mission of the WBASN is very critical, increasing the lifetime of nodes is essential in order to maintain both practicality and effectiveness. This paper presents a new Gateway Selection Algorithm (GSA) that factors in the use of energy harvesting technologies and dynamically picks the most suitable WBASN node that serves as a gateway to other wireless networks. The goal of GSA is to balance the load among the nodes by adaptively changing the gateway node in WBASN depending on the energy reserve of nodes. Computer modeling and simulations of the proposed GSA are carried out using OPNET. The simulation results demonstrate the effectiveness of the proposed GSA approach.

  6. Pliocene climate change of the Southwest Pacific and the impact of ocean gateways

    NASA Astrophysics Data System (ADS)

    Karas, Cyrus; Nürnberg, Dirk; Tiedemann, Ralf; Garbe-Schönberg, Dieter

    2011-01-01

    The transition from the early Pliocene “Warmhouse” towards the present “Icehouse” climate and the role of Gateway dynamics are intensively debated. Both, the constrictions of the Central American Seaway and the Indonesian Gateway affected ocean circulation and climate during the Pliocene epoch. Here, we use combined δ18O and Mg/Ca ratios of planktonic foraminifera (marine protozoa) from surface and subsurface levels to reconstruct the thermal structure and changes in salinities from the Southwest Pacific Deep Sea Drilling Project (DSDP) Site 590B from 6.5 to 2.5 Ma. Our data suggest a gradual cooling of ~ 2 °C and freshening of the sea surface during ~ 4.6-4 Ma with an increased meridional temperature gradient between the West Pacific Warm Pool and the Southwest Pacific when the closing of the Central American Seaway reached a critical threshold. After ~ 3.5 Ma, the restricted Indonesian Gateway might have amplified the East Australian Current, allowing enhanced heat transport towards the Southwest Pacific with reduced meridional temperature gradients when the global climate gradually cooled. At the same time our data suggest a cooling and freshening of Subantarctic Mode Water (SAMW) or/and an increased northward flow of SAMW towards Site 590B, possibly a first step towards the present Antarctic Frontal System.

  7. Overexpressing tagged proteins in plants using a modified gateway cloning strategy.

    PubMed

    Dubin, Manu J; Bowler, Chris; Benvenuto, Giovanna

    2010-03-01

    In recent years, sequence-specific recombination cloning methods such as the Gateway system have become increasingly popular for (over)expressing tagged proteins in high-throughput investigations in many different organisms, including plants. Because of their versatility and ease of use, these methods have gained favor in low- and medium-throughput investigations as well. However, due to the recombination step, the resulting fusion proteins contain long and often highly charged polylinker sequences that can interfere with their physiological function. Furthermore, in some cases the gene of interest must be cloned twice (once with and once without a stop codon) for N- and C-terminal tagging. Here, we present a hybrid combinatorial cloning strategy that overcomes many of these limitations. In the first step, the gene of interest is cloned into an entry vector containing standardized cloning sites with the desired N- or C-terminal tag and an optimized polylinker sequence. A Gateway recombination reaction is used to transfer the protein-tag fusion from the entry clone to a Gateway destination vector with the desired promoter and selectable marker for the organism of interest. As experimental requirements evolve, constructs for expressing the protein of interest with the desired tag, promoter, and selectable marker or other features can rapidly and easily be created.

  8. A simple Gateway-assisted construction system of TALEN genes for plant genome editing.

    PubMed

    Kusano, Hiroaki; Onodera, Hitomi; Kihira, Miho; Aoki, Hiromi; Matsuzaki, Hikaru; Shimada, Hiroaki

    2016-07-25

    TALEN is an artificial nuclease being applied for sequence-specific genome editing. For the plant genome editing, a pair of TALEN genes is expressed in the cells, and a binary plasmid for Agrobacterium-mediated transformation should be assembled. We developed a novel procedure using the Gateway-assisted plasmids, named Emerald-Gateway TALEN system. We constructed entry vectors, pPlat plasmids, for construction of a desired TALEN gene using Platinum Gate TALEN kit. We also created destination plasmid, pDual35SGw1301, which allowed two TALEN genes to both DNA strands to recruit using Gateway technology. Resultant TALEN genes were evaluated by the single-strand annealing (SSA) assay in E. coli cells. By this assay, the TALENs recognized the corresponding targets in the divided luciferase gene, and induced a specific recombination to generate an active luciferase gene. Using the TALEN genes constructed, we created a transformant potato cells in which a site-specific mutation occurred at the target site of the GBSS gene. This suggested that our system worked effectively and was applicable as a convenient tool for the plant genome editing.

  9. Web Sites for Young Children: Gateway to Online Social Networking?

    ERIC Educational Resources Information Center

    Bauman, Sheri; Tatum, Tanisha

    2009-01-01

    Traffic on Web sites for young children (ages 3-12) has increased exponentially in recent years. Advocates proclaim that they are safe introductions to the Internet and online social networking and teach essential 21st-century skills. Critics note developmental concerns. In this article, we provide basic information about Web sites for young…

  10. Building Awareness.

    ERIC Educational Resources Information Center

    Meilach, Dona Z.

    2001-01-01

    Discusses the importance of developing students' building awareness by exploring logos, or buildings that symbolize a country, to learn about architecture and the cultures in different countries. Explores categories of buildings. Includes examples of logos from around the world. (CMK)

  11. Geoarchaeological research of the mid-age Ilyas Bey complex buildings with ground penetrating radar in Miletus, Aydin, Western Anatolia, Turkey

    NASA Astrophysics Data System (ADS)

    Kadioğlu, S.; Kadioğlu, Y. K.; Akyol, A. A.

    2008-07-01

    The ancient Miletus which were one of the most important city of ancient Iona, are today of great value from cultural standpoint of Turkey. Miletus, situated near the village of Balat in the present district of Soke was founded on a peninsula, approximately 2.5 km long. In the Byzantine period, the city boundaries were quite reduced. In 1424 Miletus was taken inside of the Ottoman Empire and was completely abandoned in the 17th century. Ancient Miletus excavation studies were first begun in 1899 by in Berlin Museum and interrupted during the World War I. At present, the extensive restoration works in Ilyas Bey Complex has applied as a project since 2006. Ilyas Bey Complex that includes Mosque, Medresah and baths situated on the archaeological area in ancient Miletus. Impressive Mosque built in 1404 by Ilyas Bey, Emir of Menteseogullari founded in 1279 and the complex was named after him, is one of the most remarkable buildings of mid-age Miletus. There are two main purposes of the study are (1) to determine archaeological remains of the study area underneath Ilyas Bey Complex and (2) to define the nature of main rock unit and their sources in the vicinity or Aegean region. After preliminary archaeometrical studies, acquired GPR profile data paralleled each other in Ilyas Bey Mosque and its around, Medresah Courtyard and inner Courtyard of the Mosque. After processing 2D parallel GPR profiles, we constructed 3D data volume by lining processed 2D profiles up to correlate remain signatures from each profile for each studied area. It was obtained transparent 3D visualisation of GPR data by assigning a new colour scale for the amplitude range and by constructing a new opacity function instead of the linear opacity function. Therefore we could successfully image the archaeological remains in an interactive transparent 3D volume and its sub-volumes, starting at different depth levels or limited profiles. The archaeometrical (geological and mineralogical, petrographical

  12. Building the DAML Electronic Commerce Domain

    DTIC Science & Technology

    2006-05-31

    COMPUTER GATEWAYS, *COMPUTER PROGRAMMING, INFORMATION EXCHANGE, INTEROPERABILITY, PROGRAMMING LANGUAGES, SEMANTICS, INFORMATION RETRIEVAL, COMPUTER APPLICATIONS, INTERNET, BUSINESS PROCESS REENGINEERING, ELECTRONIC COMMERCE .

  13. Building the DAML Electronic Commerce Domain

    DTIC Science & Technology

    2002-02-15

    COMPUTER GATEWAYS, *COMPUTER PROGRAMMING, INFORMATION EXCHANGE, INTEROPERABILITY, PROGRAMMING LANGUAGES, SEMANTICS, INFORMATION RETRIEVAL, COMPUTER APPLICATIONS, INTERNET, BUSINESS PROCESS REENGINEERING, ELECTRONIC COMMERCE .

  14. A MultiSite GatewayTM vector set for the functional analysis of genes in the model Saccharomyces cerevisiae

    PubMed Central

    2012-01-01

    Background Recombinatorial cloning using the GatewayTM technology has been the method of choice for high-throughput omics projects, resulting in the availability of entire ORFeomes in GatewayTM compatible vectors. The MultiSite GatewayTM system allows combining multiple genetic fragments such as promoter, ORF and epitope tag in one single reaction. To date, this technology has not been accessible in the yeast Saccharomyces cerevisiae, one of the most widely used experimental systems in molecular biology, due to the lack of appropriate destination vectors. Results Here, we present a set of three-fragment MultiSite GatewayTM destination vectors that have been developed for gene expression in S. cerevisiae and that allow the assembly of any promoter, open reading frame, epitope tag arrangement in combination with any of four auxotrophic markers and three distinct replication mechanisms. As an example of its applicability, we used yeast three-hybrid to provide evidence for the assembly of a ternary complex of plant proteins involved in jasmonate signalling and consisting of the JAZ, NINJA and TOPLESS proteins. Conclusion Our vectors make MultiSite GatewayTM cloning accessible in S. cerevisiae and implement a fast and versatile cloning method for the high-throughput functional analysis of (heterologous) proteins in one of the most widely used model organisms for molecular biology research. PMID:22994806

  15. Transnational Strategies for the Promotion of Physical Activity and Active Aging: The World Health Organization Model of Consensus Building in International Public Health

    ERIC Educational Resources Information Center

    Chodzko-Zajko, Wojtek; Schwingel, Andiara

    2009-01-01

    In this paper we focus our attention on an examination of the four-step process adopted by the World Health Organization (WHO) in its systematic campaign to promote physically active lifestyles by older adults across the 193 WHO member states. The four steps adopted by the WHO include (1) Building Consensus Among Professionals; (2) Educating the…

  16. Preventing painful age-related bone fractures: Anti-sclerostin therapy builds cortical bone and increases the proliferation of osteogenic cells in the periosteum of the geriatric mouse femur.

    PubMed

    Thompson, Michelle L; Chartier, Stephane R; Mitchell, Stefanie A; Mantyh, Patrick W

    2016-01-01

    Age-related bone fractures are usually painful and have highly negative effects on a geriatric patient's functional status, quality of life, and survival. Currently, there are few analgesic therapies that fully control bone fracture pain in the elderly without significant unwanted side effects. However, another way of controlling age-related fracture pain would be to preemptively administer an osteo-anabolic agent to geriatric patients with high risk of fracture, so as to build new cortical bone and prevent the fracture from occurring. A major question, however, is whether an osteo-anabolic agent can stimulate the proliferation of osteogenic cells and build significant amounts of new cortical bone in light of the decreased number and responsiveness of osteogenic cells in aging bone. To explore this question, geriatric and young mice, 20 and 4 months old, respectively, received either vehicle or a monoclonal antibody that sequesters sclerostin (anti-sclerostin) for 28 days. From days 21 to 28, animals also received sustained administration of the thymidine analog, bromodeoxyuridine (BrdU), which labels the DNA of dividing cells. Animals were then euthanized at day 28 and the femurs were examined for cortical bone formation, bone mineral density, and newly borne BrdU+ cells in the periosteum which is a tissue that is pivotally involved in the formation of new cortical bone. In both the geriatric and young mice, anti-sclerostin induced a significant increase in the thickness of the cortical bone, bone mineral density, and the proliferation of newly borne BrdU+ cells in the periosteum. These results suggest that even in geriatric animals, anti-sclerostin therapy can build new cortical bone and increase the proliferation of osteogenic cells and thus reduce the likelihood of painful age-related bone fractures.

  17. GateWay Community College Water Resources Program Partnerships: An Opportunity for Program Success and Collaboration

    NASA Astrophysics Data System (ADS)

    Castaneda, M.

    2012-12-01

    GateWay Community College Water Resources Technologies (WRT) Program offers Certificate of Completions and Associate Degrees on Hydrologic Studies, Water Treatment and Wastewater Treatment. The program has been in existence since 1998 and has gone through several updates to meet the demand for professionals in those areas. The program includes theoretical and practical hands-on training in the monitoring of water quality and quantity as well as in water and industrial wastewater treatment. The WRT program offers online, face-to-face, and hybrid courses to address different student's needs for training. The program only Full-time faculty is supported by 15 adjunct- faculty professionals. Adjunct faculty is usually hired from a wide variety of professional people already working in the industry that have shown interest on teaching. Adjunct faculty also provide free tutoring to the WRT students when they are not teaching courses. The college Learning Center provides funding to support these tutoring activities. The program has an active Advisory Committee that provides guidance and recommends program changes to meet their training needs. This Advisory Committee is made of professionals from different federal, state, county agencies, and municipalities, private industry and consulting companies in the area. The Advisory Committee meets every year to provide feedback to GateWay on curriculum changes and commit to potential internship opportunities for the WRT students. Those internships (or voluntary work) are paid directly by the municipalities or agencies or can be paid by the GateWay WRT program. These internship jobs provides with an opportunity to actively promote the WRT program throughout the valley. The GateWay WRT program considers the Advisory Committee an essential component for the program success: the committee supports the program in recommending and acquiring the latest field equipment needed for the hands-on training. One of the main WRT program

  18. Marine Isotope Stages (MIS) 96-101: Glacial induced closure of the Panamanian Gateway

    NASA Astrophysics Data System (ADS)

    Groeneveld, Jeroen; Debey, Henry; Hathorne, Ed C.; Steinke, Stephan

    2010-05-01

    We present combined Mg/Ca and δ18O measurements from ODP Site 1241 from the east Pacific and ODP Site 999 from the Caribbean. The studied time interval covers the first major glacial-interglacial cycles (MIS96-101) after intensification of Northern Hemisphere Glaciation. Analyses were performed on the planktic foraminifers Neogloboquadrina dutertrei and Globigerinoides sacculifer, representing water mass properties in the thermocline and the mixed layer respectively. Data resolution is aimed to be able to resolve millennial scale variations to constrain the changes in water mass conditions during MIS96-101. Aim of the study is to test the theory that the Panamanian Gateway temporarily closed during glacial MIS 96, 98, and 100 due to a drop in sea level of 50-80 m. This was first suggested in Groeneveld et al., (in prep.) and might have provided the necessary conditions to allow the Great American Biotic Interchange, the large scale migration of mammals from South to North America and vice versa. As this exchange would have required more arid conditions in Central America to allow the fauna, which was mainly adapted to a savannah-like environment, to cross, a glacial period would have provided the right conditions. Reconstruction of sea water temperatures can indicate if and when the gateway closed. With an open Panamanian Gateway relatively cold water flowed from the Pacific into the Caribbean. With the onset of glacial conditions sea surface temperatures (SST) expectedly would show a decrease in the east Pacific (Site 1241). But, SSTs in the Caribbean (Site 999) are expected to rise as no longer relatively cold Pacific water is entering the Caribbean, but rather the warmer waters from the Western Atlantic Warm Pool advanced from the north to the core location. Indeed, reconstructed SSTs from G. sacculifer show a decrease of 2.5° C at Site 1241 and an increase of 3° C at Site 999 suggesting that the Panamanian Gateway truly was closed during the glacial stage

  19. Disaster Response Tools for Decision Support and Data Discovery - E-DECIDER and GeoGateway

    NASA Astrophysics Data System (ADS)

    Glasscoe, M. T.; Donnellan, A.; Parker, J. W.; Granat, R. A.; Lyzenga, G. A.; Pierce, M. E.; Wang, J.; Grant Ludwig, L.; Eguchi, R. T.; Huyck, C. K.; Hu, Z.; Chen, Z.; Yoder, M. R.; Rundle, J. B.; Rosinski, A.

    2015-12-01

    Providing actionable data for situational awareness following an earthquake or other disaster is critical to decision makers in order to improve their ability to anticipate requirements and provide appropriate resources for response. E-DECIDER (Emergency Data Enhanced Cyber-Infrastructure for Disaster Evaluation and Response) is a decision support system producing remote sensing and geophysical modeling products that are relevant to the emergency preparedness and response communities and serves as a gateway to enable the delivery of actionable information to these communities. GeoGateway is a data product search and analysis gateway for scientific discovery, field use, and disaster response focused on NASA UAVSAR and GPS data that integrates with fault data, seismicity and models. Key information on the nature, magnitude and scope of damage, or Essential Elements of Information (EEI), necessary to achieve situational awareness are often generated from a wide array of organizations and disciplines, using any number of geospatial and non-geospatial technologies. We have worked in partnership with the California Earthquake Clearinghouse to develop actionable data products for use in their response efforts, particularly in regularly scheduled, statewide exercises like the recent May 2015 Capstone/SoCal NLE/Ardent Sentry Exercises and in the August 2014 South Napa earthquake activation. We also provided a number of products, services, and consultation to the NASA agency-wide response to the April 2015 Gorkha, Nepal earthquake. We will present perspectives on developing tools for decision support and data discovery in partnership with the Clearinghouse and for the Nepal earthquake. Products delivered included map layers as part of the common operational data plan for the Clearinghouse, delivered through XchangeCore Web Service Data Orchestration, enabling users to create merged datasets from multiple providers. For the Nepal response effort, products included models

  20. The Opening of the Arctic-Atlantic Gateway: Tectonic, Oceanographic and Climatic Dynamics - an IODP Initiative

    NASA Astrophysics Data System (ADS)

    Geissler, W. H.; Knies, J.; Nielsen, T.; Gaina, C.; Matthiessen, J. J.; Gebhardt, C.; Damm, V.; Forwick, M.; Hjelstuen, B. O.; Hopper, J. R.; Husum, K.; Laberg, J. S.; Kuerschner, W.; Morigi, C.; Schreck, M.; Tripati, A. K.; Vogt, C. M.; Rebesco, M.; Nam, S. I.; Carlson, A. E.; De Schepper, S.; Lucchi, R.; Mattingsdal, R.; Jokat, W.; Stein, R. H.

    2014-12-01

    The modern polar cryosphere reflects an extreme climate state with profound temperature gradients towards high-latitudes. It developed in association with stepwise Cenozoic cooling, beginning with ephemeral glaciations and the appearance of sea ice in the late middle Eocene. The polar ocean gateways played a pivotal role in changing the polar and global climate, along with declining greenhouse gas levels. The opening of the Drake Passage finalized the oceanographic isolation of Antarctica, some 40 Ma ago. The Arctic Ocean was an isolated basin until the early Miocene when rifting and subsequent sea-floor spreading started between Greenland and Svalbard, initiating the opening of the Fram Strait / Arctic-Atlantic Gateway (AAG). Although this gateway is known to be important in Earth's past and modern climate, little is known about its Cenozoic development. However, the opening history and AAG's consecutive widening and deepening must have had a strong impact on circulation and water mass exchange between the Arctic Ocean and the North Atlantic. To study the AAG's complete history, ocean drilling at two primary sites and one alternate site located between 73°N and 78°N are proposed. These sites will provide unprecedented sedimentary records that will unveil (1) the history of shallow-water exchange between the Arctic Ocean and the North Atlantic, and (2) the development of the AAG to a deep-water connection and its influence on the global climate system. The specific overarching goals of our proposal are to study: • the influence of distinct tectonic events in the development of the AAG and the formation of deep water passage on the North Atlantic and Arctic paleoceanography, and • the role of the AAG in the climate transition from the Paleogene greenhouse to the Neogene icehouse for the long-term (~50 Ma) climate history of the northern North Atlantic.

  1. Ariadne's thread: biomedical gateways to not get lost in the Internet labyrinth.

    PubMed

    Giglia, E

    2008-03-01

    The more the Internet grows, the more a researcher has to cope with the so called ''information overload'', or ''data deluge''. Reliability, updating, authoritativeness of a Web site ought to be a requirement, all the more reason for the biomedical field. During the past years libraries and information specialists have been developing projects, such as gateways and virtual reference desks, aimed at supplying trustworthy health information in Web sites. Purpose of this contribution is to present these tools, in order to improve one's search skills.

  2. TIS: an Intelligent Gateway Computer for information and modeling networks. Overview

    SciTech Connect

    Hampel, V.E.; Bailey, C.; Kawin, R.A.; Lann, N.A.; McGrogan, S.K.; Scott, W.S.; Stammers, S.M.; Thomas, J.L.

    1983-08-01

    The Technology Information System (TIS) is being used to develop software for Intelligent Gateway Computers (IGC) suitable for the prototyping of advanced, integrated information networks. Dedicated to information management, TIS leads the user to available information resources, on TIS or elsewhere, by means of a master directory and automated access procedures. Other geographically distributed information centers accessible through TIS include federal and commercial systems like DOE/RECON, NASA/RECON, DOD/DROLS, DOT/TIC, CIS, and DIALOG in the United States, the chemical information systems DARC in France, and DECHEMA in West Germany. New centers are added as required.

  3. Building America

    SciTech Connect

    Brad Oberg

    2010-12-31

    IBACOS researched the constructability and viability issues of using high performance windows as one component of a larger approach to building houses that achieve the Building America 70% energy savings target.

  4. State of gas exchange in recumbent and orthostatic positions and under physical load in healthy persons of varying age, sex and body build

    NASA Technical Reports Server (NTRS)

    Glezer, G. A.; Charyyev, M.; Zilbert, N. L.

    1980-01-01

    Age effect on gas exchange was studied in the recumbent and orthostatic positions and under physical load. In the case of the older age group and for normal as compared with hypersthenic persons, oxygen consumption during rest and during moderate physical overload diminishes. When the vertical position is assumed oxygen consumption in persons of various age groups is distinctly increased, particularly in the elderly group. There is a reduction in the amount of oxygen consumption, oxygen pulse, recovery coefficient, and work efficiency under moderate overload. In persons over 50, physical labor induces a large oxygen requirement and a sharp rise in the level of lactic acid and the blood's lactate/pyruvate ratio. No distinct difference was noted in the amount of oxygen consumed during rest and during physical overload in men and women of the same physical development and age.

  5. Healthy Buildings?

    ERIC Educational Resources Information Center

    Grubb, Deborah

    Health problems related to school buildings can be categorized in five major areas: sick-building syndrome; health-threatening building materials; environmental hazards such as radon gas and asbestos; lead poisoning; and poor indoor air quality due to smoke, chemicals, and other pollutants. This paper provides an overview of these areas,…

  6. Integrating QoS and security functions in an IP-VPN gateway

    NASA Astrophysics Data System (ADS)

    Fan, Kuo-Pao; Chang, Shu-Hsin; Lin, Kuan-Ming; Pen, Mau-Jy

    2001-10-01

    IP-based Virtual Private Network becomes more and more popular. It can not only reduce the enterprise communication cost but also increase the revenue of the service provider. The common IP-VPN application types include Intranet VPN, Extranet VPN, and remote access VPN. For the large IP-VPN market, some vendors develop dedicated IP-VPN devices; while some vendors add the VPN functions into their existing network equipment such as router, access gateway, etc. The functions in the IP-VPN device include security, QoS, and management. The common security functions supported are IPSec (IP Security), IKE (Internet Key Exchange), and Firewall. The QoS functions include bandwidth control and packet scheduling. In the management component, policy-based network management is under standardization in IETF. In this paper, we discuss issues on how to integrate the QoS and security functions in an IP-VPN Gateway. We propose three approaches to do this. They are (1) perform Qos first (2) perform IPSec first and (3) reserve fixed bandwidth for IPSec. We also compare the advantages and disadvantages of the three proposed approaches.

  7. VisIVO: A Web-Based, Workflow-Enabled Gateway for Astrophysical Visualization

    NASA Astrophysics Data System (ADS)

    Costa, A.; Bandieramonte, M.; Becciani, U.; Krokos, M.; Massimino, P.; Petta, C.; Pistagna, C.; Riggi, S.; Sciacca, E.; Vitello, F.

    2013-10-01

    We present a web-based and workflow-enabled framework called VisIVO Gateway that allows integration of large-scale multidimensional datasets together with applications for visualization and exploration on Distributed Computing Infrastructures (DCIs). Our framework is implemented through a workflow-enabled portal wrapped around WS-PGRADE which is the grid User Support Environment (gUSE) portal. We provide customized interfaces for creating, invoking, monitoring and also modifying scientific workflows. All technical complexities, e.g. related to visualization algorithms and DCI configurations, are conveniently hidden from view. A number of workflows are enabled by default, e.g. implementing local or remote uploading and creation of scientific movies. Scientific movies are useful not only to scientists for presenting their research results, but also to museums and science centers for engaging visitors with complex scientific concepts. Our gateway can be accessed via standard www interfaces but also through a newly developed iOS mobile application offering novel ways for sharing analysis and exploration experiences with large-scale datasets in collaborative environments.

  8. Design and realization of a wireless sensor gateway for health monitoring.

    PubMed

    Becher, K; Figueiredo, C P; Muhle, C; Ruff, R; Mendes, P M; Hoffmann, K P

    2010-01-01

    This paper describes the design and realization of a wireless sensor gateway (WSG) within a wireless sensor network (WSN) for health monitoring. The WSN allows recording and wireless transmission of biosignals, namely the electrocardiogram, pulse wave and body weight, which are important parameters for cardiovascular monitoring. These can be displayed, analysed, and saved on the WSG through a user interface based on a touch screen. The proposed WSG has the distinctive feature of using two different radio transceivers, exploiting the advantages of each device. Currently, most personal computers and handhelds have standardized Bluetooth interfaces (IEEE 802.15.1) but not ZigBee interfaces (IEEE 802.15.4). Hence, the proposed gateway is designed to receive data from wireless sensors through its ZigBee interface and to forward them to a personal computer via its Bluetooth interface. This feature, combined with simple touch screen menu navigation will reach increased patient compliance and consequently increased benefit for patient in terms of healthcare and safety.

  9. On the capability of smartphones to perform as communication gateways in medical wireless personal area networks.

    PubMed

    Morón, María José; Luque, Rafael; Casilari, Eduardo

    2014-01-02

    This paper evaluates and characterizes the technical performance of medical wireless personal area networks (WPANs) that are based on smartphones. For this purpose,a prototype of a health telemonitoring system is presented. The prototype incorporates a commercial Android smartphone, which acts as a relay point, or "gateway", between a set of wireless medical sensors and a data server. Additionally, the paper investigates if the conventional capabilities of current commercial smartphones can be affected by their use as gateways or "Holters" in health monitoring applications. Specifically, the profiling has focused on the CPU and power consumption of the mobile devices. These metrics have been measured under several test conditions modifying the smartphone model, the type of sensors connected to the WPAN, the employed Bluetooth profile (SPP (serial port profile) orHDP (health device profile)), the use of other peripherals, such as a GPS receiver, the impact of the use of the Wi-Fi interface or the employed method to encode and forward the data that are collected from the sensors.

  10. Identifying causal gateways and mediators in complex spatio-temporal systems

    NASA Astrophysics Data System (ADS)

    Runge, Jakob; Petoukhov, Vladimir; Donges, Jonathan; Hlinka, Jaroslav; Jajcay, Nikola; Vejmelka, Martin; Hartman, David; Marwan, Norbert; Palus, Milan; Kurths, Jürgen

    2016-04-01

    Identifying regions important for spreading and mediating perturbations is crucial to assess the susceptibilities of spatio-temporal complex systems such as the Earth's climate to volcanic eruptions, extreme events or geoengineering. Here a data-driven approach is introduced based on a dimension reduction, causal reconstruction, and novel network measures based on causal effect theory that go beyond standard complex network tools by distinguishing direct from indirect pathways. Applied to a data set of atmospheric dynamics, the method identifies several strongly uplifting regions acting as major gateways of perturbations spreading in the atmosphere. Additionally, the method provides a stricter statistical approach to pathways of atmospheric teleconnections, yielding insights into the Pacific-Indian Ocean interaction relevant for monsoonal dynamics. The novel causal interaction perspective provides a complementary approach to simulations or experiments for understanding the functioning of complex spatio-temporal systems with potential applications in increasing their resilience to shocks or extreme events. Reference: Runge, J., Petoukhov, V., Donges, J. F., Hlinka, J., Jajcay, N., Vejmelka, M., Hartman, D., Marwan, M., Paluš, M., Kurths, J. (2015). Identifying causal gateways and mediators in complex spatio-temporal systems. Nature Communications, 6, 8502. doi:10.1038/ncomms9502

  11. Data gateway for prognostic health monitoring of ocean-based power generation

    NASA Astrophysics Data System (ADS)

    Gundel, Joseph

    On August 5, 2010 the U.S. Department of Energy (DOE) has designated the Center for Ocean Energy Technology (COET) at Florida Atlantic University (FAU) as a national center for ocean energy research and development. Their focus is the research and development of open-ocean current systems and associated infrastructure needed to development and testing prototypes. The generation of power is achieved by using a specialized electric generator with a rotor called a turbine. As with all machines, the turbines will need maintenance and replacement as they near the end of their lifecycle. This prognostic health monitoring (PHM) requires data to be collected, stored, and analyzed in order to maximize the lifespan, reduce downtime and predict when failure is eminent. This thesis explores the use of a data gateway which will separate high level software with low level hardware including sensors and actuators. The gateway will standardize and store the data collected from various sensors with different speeds, formats, and interfaces allowing an easy and uniform transition to a database system for analysis.

  12. What Is in a Textbook? Investigating the Language and Literacy Learning Principles of the "Gateway to English" Textbook Series

    ERIC Educational Resources Information Center

    Opoku-Amankwa, Kwasi; Brew-Hammond, Aba; Kofigah, Francis Elsbend

    2011-01-01

    This paper investigates three English textbooks for primary classes 4, 5 and 6 in Ghana from the "Gateway to English for Primary Schools" series, and their complementary teachers' guides, in order to determine the assumptions about teaching and learning which the books embody. The paper pays particular attention to the approach to…

  13. Long-Range Plan for Gateway Technical Institute. 1982-1987: Serving Kenosha, Racine, and Walworth Counties.

    ERIC Educational Resources Information Center

    Stoehr, Keith W.; Covelli, Nicholas J.

    This report presents Gateway Technical Institute's long-range plan for 1982-1987. After prefatory material discussing financial and non-financial factors that may impinge on the plan, Chapter I outlines the socioeconomic situation in the three-county area of Wisconsin served by the college and introduces some of the critical issues that the…

  14. D1/D5 Receptors and Histone Deacetylation Mediate the Gateway Effect of LTP in Hippocampal Dentate Gyrus

    ERIC Educational Resources Information Center

    Huang, Yan-You; Lavine, Amir; Kandel, Denise B.; Yin, Deqi; Colnaghi, Luca; Drisaldi, Bettina; Kandel, Eric R.

    2014-01-01

    The dentate gyrus (DG) of the hippocampus is critical for spatial memory and is also thought to be involved in the formation of drug-related associative memory. Here, we attempt to test an aspect of the Gateway Hypothesis, by studying the effect of consecutive exposure to nicotine and cocaine on long-term synaptic potentiation (LTP) in the DG. We…

  15. Gateway to Healthcare Careers for Vulnerable Students: A New Approach to the Teaching of Anatomy and Physiology

    ERIC Educational Resources Information Center

    DeCiccio, Albert; Kenny, Tammy; Lippacher, Linda; Flanary, Barry

    2011-01-01

    At Southern Vermont College (SVC) and at the nation's other colleges and universities, Anatomy and Physiology I (A&PI) is the gateway course into healthcare careers. Disturbingly, at SVC and elsewhere, many first-year students interested in healthcare careers do not succeed in this course. They withdraw from the course or the institution, or…

  16. 76 FR 18241 - Notice of Intent To Prepare an Environmental Impact Statement for the Proposed Energy Gateway...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ..., potentially crossing northwestern Colorado. The Project would include a single-circuit 500-kV AC transmission...-Kilovolt (kV) Alternating Current Transmission Line Project in Wyoming, Colorado, and Utah, and Possible...South_WYMail@blm.gov . SUPPLEMENTARY INFORMATION: The EIS for the Proposed Energy Gateway South...

  17. 75 FR 41276 - US Rail Partners, Ltd. and Blackwell Northern Gateway Railroad Company-Continuance in Control...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ... modified certificate of public convenience and necessity in STB Finance Docket No. 35383, Eastern Berks Gateway Railroad Company-- ] Modified Rail Certificate, wherein EBGR seeks to lease and operate... Railroad Company (EWGR). BNGR operates approximately 35 miles of rail line between Wellington, Kan.,...

  18. First Annual Mock Job Fair "Gateway to Success," Federal Correctional Institution, Terminal Island. Summary Report and Evaluation.

    ERIC Educational Resources Information Center

    Caswell, Cal

    A "Gateway to Success" Mock Job Fair Program was conducted at Federal Correction Institute, Terminal Island. Prior to participation, inmates and employers were administered a pre-program needs assessment questionnaire to determine expectations. Results of the program evaluations (completed by inmates and employers) documented a need for…

  19. Effects of Sentence Instruction and Frequency Building to a Performance Criterion on Elementary-Aged Students with Behavioral Concerns and EBD

    ERIC Educational Resources Information Center

    Datchuk, Shawn M.; Kubina, Richard M.; Mason, Linda H.

    2015-01-01

    Elementary-aged students with behavioral concerns and disabilities struggling to construct sentences stand a high likelihood for continued academic difficulty. Several studies have used sentence instruction with picture-word prompts to improve sentence level writing skills, including construction of simple sentences, syntax, capitalization, and…

  20. No Own-Age Bias in 3-Year-Old Children: More Evidence for the Role of Early Experience in Building Face-Processing Biases

    ERIC Educational Resources Information Center

    Cassia, Viola Macchi; Pisacane, Antonella; Gava, Lucia

    2012-01-01

    This study aimed to investigate the presence of an own-age bias in young children who accumulated different amounts of early experience with child faces. Discrimination abilities for upright and inverted adult and child faces were tested using a delayed two-alternative, forced-choice matching-to-sample task in two groups of 3-year-old children,…

  1. Learning Gateways.

    ERIC Educational Resources Information Center

    Insights on Law & Society, 2001

    2001-01-01

    Provides a lesson that focuses on the history of voter representation in the United States. Explains that students will read, "Whose Voice Is Heard,""How Should U.S. Elections Be Managed?," and other student handouts in this issue of "Insights on Law and Society." (CMK)

  2. Learning Gateways.

    ERIC Educational Resources Information Center

    Ryan, John Paul

    2002-01-01

    Includes a lesson plan that educates students about the rights of youth, which is the theme of this issue of "Insights on Law and Society." Explains that the students must read the article, "The Bill of Rights and the School Curriculum," included in this issue. Includes a handout. (CMK)

  3. Learning Gateways.

    ERIC Educational Resources Information Center

    Insights on Law & Society, 2001

    2001-01-01

    Provides a lesson plan with activities using the materials presented in this issue of "Insights on Law and Society" as a basis to test students' critical skills. Focuses on the topic of religious freedom and the ideas of James Madison and Patrick Henry on civil order. Includes a student handout. (CMK)

  4. Building a discovery partnership with Sarawak Biodiversity Centre: a gateway to access natural products from the rainforests.

    PubMed

    Yeo, Tiong Chia; Naming, Margarita; Manurung, Rita

    2014-03-01

    The Sarawak Biodiversity Centre (SBC) is a state government agency which regulates research and promotes the sustainable use of biodiversity. It has a program on documentation of traditional knowledge (TK) and is well-equipped with facilities for natural product research. SBC maintains a Natural Product Library (NPL) consisting of local plant and microbial extracts for bioprospecting. The NPL is a core discovery platform for screening of bioactive compounds by researchers through a formal agreement with clear benefit sharing obligations. SBC aims to develop partnerships with leading institutions and the industries to explore the benefits of biodiversity.

  5. Laboratory Building

    SciTech Connect

    Herrera, Joshua M.

    2015-03-01

    This report is an analysis of the means of egress and life safety requirements for the laboratory building. The building is located at Sandia National Laboratories (SNL) in Albuquerque, NM. The report includes a prescriptive-based analysis as well as a performance-based analysis. Following the analysis are appendices which contain maps of the laboratory building used throughout the analysis. The top of all the maps is assumed to be north.

  6. The Opening of the Arctic-Atlantic Gateway: Tectonic, Oceanographic and Climatic Dynamics - an IODP Initiative

    NASA Astrophysics Data System (ADS)

    Geissler, Wolfram; Knies, Jochen

    2016-04-01

    The modern polar cryosphere reflects an extreme climate state with profound temperature gradients towards high-latitudes. It developed in association with stepwise Cenozoic cooling, beginning with ephemeral glaciations and the appearance of sea ice in the late middle Eocene. The polar ocean gateways played a pivotal role in changing the polar and global climate, along with declining greenhouse gas levels. The opening of the Drake Passage finalized the oceanographic isolation of Antarctica, some 40 Ma ago. The Arctic Ocean was an isolated basin until the early Miocene when rifting and subsequent sea-floor spreading started between Greenland and Svalbard, initiating the opening of the Fram Strait / Arctic-Atlantic Gateway (AAG). Although this gateway is known to be important in Earth's past and modern climate, little is known about its Cenozoic development. However, the opening history and AAG's consecutive widening and deepening must have had a strong impact on circulation and water mass exchange between the Arctic Ocean and the North Atlantic. To study the AAG's complete history, ocean drilling at two primary sites and one alternate site located between 73°N and 78°N in the Boreas Basin and along the East Greenland continental margin are proposed. These sites will provide unprecedented sedimentary records that will unveil (1) the history of shallow-water exchange between the Arctic Ocean and the North Atlantic, and (2) the development of the AAG to a deep-water connection and its influence on the global climate system. The specific overarching goals of our proposal are to study: (1) the influence of distinct tectonic events in the development of the AAG and the formation of deep water passage on the North Atlantic and Arctic paleoceanography, and (2) the role of the AAG in the climate transition from the Paleogene greenhouse to the Neogene icehouse for the long-term (~50 Ma) climate history of the northern North Atlantic. Getting a continuous record of the

  7. NASA gateways at L1 and L2 and the radio-quiet Moon Farside imperative

    NASA Astrophysics Data System (ADS)

    Maccone, Claudio

    2005-07-01

    NASA is currently studying the possibility of establishing future space bases at either of the libration points (also called Lagrangian points) L1 and L2 of the Earth Moon system. Two more similar points L1 and L2 of the Sun Earth system are also under consideration. Such possible future space bases are called Gateways in the NASA jargon. Each Gateway has its own pros and cons in terms of gravitational pull, distance from the Earth, and targets attainable by future spacecraft departing from the Gateway. A preliminary, concise review of these alternative possibilities is presented in this paper. We claim, however, that an extra factor has to be included in the NASA scenario also. This is the Radio-Quiet Moon Farside Imperative, called simply the Farside Imperative hereafter. This imperative is the need to keep at least the central part of the Farside of the Moon free from Radio Frequency Interference (RFI) coming from the Earth and shielded by the Moon's spherical body. In fact, the Farside of the Moon, and the Quiet Cone that extends into space above it for a few thousands of kilometers, represent a unique outpost for humankind: they are the only place close to the Earth where all radio-garbage produced by modern human civilization cannot reach. Thus, an array of radio antennas located there would sense the rest of the universe to an unprecedented degree of radio cleanliness, and, hence, of radio details. Not only would astrophysics and radio astronomy in general greatly benefit from this radio-quiet environment, but we would possibly achieve there for the first time a neat radio contact with an extraterrestrial civilization harboring somewhere else in the Galaxy (SETI) that could be too noisy to be detected on Earth. It is thus felt that a fair balance has to be reached between the astronautical drive to enlarge the exploration of the solar system and the imperative to keep the Farside of the Moon radio-clean. This paper puts forward a set of constructing

  8. The Gateway Paper--financing health in Pakistan and its linkage with health reforms.

    PubMed

    Nishtar, Sania

    2006-12-01

    Pakistan currently principally uses three modes of financing health--taxation, out of pocket payments and donor contributions of which the latter is the least significant in terms of size. Less than 3.6% of the employees are covered under the social security scheme and there is a limited social protection mechanism, which collectively serves the health needs of 3.4% of the population. The main issues in health financing include low spending, lack of attention to alternate sources of financing and issues with fund mobilization and utilization. With respect to the first, health reforms proposed as part of the Gateway Paper make a strong case for promoting the reallocation of tax-based revenues and developing sustainable alternatives to low levels of public spending on health. With respect to alternative sources of health financing, the Gateway Paper lays stress on exploring policy options for private health insurance, broadening the base of Employees Social Security, creating a Federal Employees Social Security Programme, developing social health insurance within the framework of a broad-based social protection strategy, which scopes beyond the formally employed sector, establishing a widely inclusive safety net for the poor; mainstreaming philanthropic grants as a major source of health financing; developing a conducive tax configuration; generating greater corporate support for social sector causes within the framework of the concept of Corporate Social Responsibility and developing cost-sharing programmes, albeit with safeguards. The Gateway Paper regards efficient fund utilization a priority and lays stress on striking a balance between minimizing costs, controlling costs and using resources more efficiently and equitably--in other words, getting the best value for the money, on the one hand, and increasing the pool of available resources, on the other. Specific interventions such as the promotion of transparent financial administration, budgeting and cost

  9. ECOMS-UDG. A User-friendly Data access Gateway to seasonal forecast datasets allowing R-based remote data access, visualization-validation, bias correction and downscaling

    NASA Astrophysics Data System (ADS)

    Santiago Cofiño, Antonio; Gutiérrez, José Manuel; Fernández, Jesús; Bedia, Joaquín; Vega, Manuel; Herrera, Sixto; Frías, María Dolores; Iturbide, Maialen; Magariño, Maria Eugenia; Manzanas, Rodrigo

    2016-04-01

    Seasonal forecasting data from state-or-the-art forecasting systems (e.g. NCEP/CFSv2 or ECMWF/System4) can be obtained directly from the data providers, but the resulting formats, aggregations and vocabularies may not be homogeneous across datasets, requiring some post processing. Moreover, different data policies hold for the various datasets - which are freely available only in some cases - and therefore data access may not be straightforward. Thus, obtaining seasonal climate forecast data is typically a time consuming task. The ECOMS-UDG (User Data Gateway for the ECOMS initiative) has been developed building in the ​User Data Gateway (UDG, http://meteo.unican.es/udg-wiki) in order to facilitate seasonal (re)forecast data access to end users. The required variables have been downloaded from data providers and stored locally in a THREDDS data server implementing fine-grained user authorization. Thus, users can efficiently retrieve the subsets that best suits their particular research aims (typically surface variables for certain regions, periods and/or ensemble members) from a large volume of information. Moreover, an interface layer developed in R allows remote data exploration, access (including homogenization, collocation and sub-setting) and the integration of ECOMS-UDG with a number of R packages developed in the framework of ECOMS for forecast visualization, validation, bias correction and downscaling. This unique framework oriented to climate services allows users from different sectors to easily access seasonal forecasting data (typically surface variables), calibrating and/or downscaling (using upper air information from large scale predictors) this data at local level and validating the different results (using observations). The documentation delivered with the packages includes worked examples showing that the whole visualization, bias correction and/or downscaling tasks requires only a few lines of code and are fully reproducible and adaptable to

  10. A solution for archiving and retrieving preclinical molecular imaging data in PACS using a DICOM gateway

    NASA Astrophysics Data System (ADS)

    Lee, Jasper; Liu, Bihui; Liu, Brent

    2011-03-01

    Advances in biology, computer technology and imaging technology have given rise to a scientific specialty referred to as molecular imaging, which is the in vivo imaging of cellular and molecular pathways using contrast-enhancing targeting agents. Increasing amounts of molecular imaging research are being performed at pre-clinical stages, generating diverse datasets that are unstructured and thereby lacking in archiving and distribution solutions. Since PACS in radiology is a mature clinical archiving solution, a method is proposed to convert current imaging files from preclinical molecular imaging studies into DICOM formats for archival and retrieval from PACS systems. A web-based DICOM gateway is presented with an emphasis on metadata mapping in the DICOM header, system connectivity, and overall user workflow. This effort to conform preclinical imaging data to the DICOM standard is necessary to utilize current PACS solutions for preclinical imaging data content archiving and distribution.

  11. Gateway-Assisted Retransmission for Lightweight and Reliable IoT Communications

    PubMed Central

    Chang, Hui-Ling; Wang, Cheng-Gang; Wu, Mong-Ting; Tsai, Meng-Hsun; Lin, Chia-Ying

    2016-01-01

    Message Queuing Telemetry Transport for Sensor Networks (MQTT-SN) and Constrained Application Protocol (CoAP) are two protocols supporting publish/subscribe models for IoT devices to publish messages to interested subscribers. Retransmission mechanisms are introduced to compensate for the lack of data reliability. If the device does not receive the acknowledgement (ACK) before retransmission timeout (RTO) expires, the device will retransmit data. Setting an appropriate RTO is important because the delay may be large or retransmission may be too frequent when the RTO is inappropriate. We propose a Gateway-assisted CoAP (GaCoAP) to dynamically compute RTO for devices. Simulation models are proposed to investigate the performance of GaCoAP compared with four other methods. The experiment results show that GaCoAP is more suitable for IoT devices. PMID:27669243

  12. Identifying causal gateways and mediators in complex spatio-temporal systems

    NASA Astrophysics Data System (ADS)

    Runge, Jakob; Petoukhov, Vladimir; Donges, Jonathan F.; Hlinka, Jaroslav; Jajcay, Nikola; Vejmelka, Martin; Hartman, David; Marwan, Norbert; Paluš, Milan; Kurths, Jürgen

    2015-10-01

    Identifying regions important for spreading and mediating perturbations is crucial to assess the susceptibilities of spatio-temporal complex systems such as the Earth's climate to volcanic eruptions, extreme events or geoengineering. Here a data-driven approach is introduced based on a dimension reduction, causal reconstruction, and novel network measures based on causal effect theory that go beyond standard complex network tools by distinguishing direct from indirect pathways. Applied to a data set of atmospheric dynamics, the method identifies several strongly uplifting regions acting as major gateways of perturbations spreading in the atmosphere. Additionally, the method provides a stricter statistical approach to pathways of atmospheric teleconnections, yielding insights into the Pacific-Indian Ocean interaction relevant for monsoonal dynamics. Also for neuroscience or power grids, the novel causal interaction perspective provides a complementary approach to simulations or experiments for understanding the functioning of complex spatio-temporal systems with potential applications in increasing their resilience to shocks or extreme events.

  13. Identifying causal gateways and mediators in complex spatio-temporal systems.

    PubMed

    Runge, Jakob; Petoukhov, Vladimir; Donges, Jonathan F; Hlinka, Jaroslav; Jajcay, Nikola; Vejmelka, Martin; Hartman, David; Marwan, Norbert; Paluš, Milan; Kurths, Jürgen

    2015-10-07

    Identifying regions important for spreading and mediating perturbations is crucial to assess the susceptibilities of spatio-temporal complex systems such as the Earth's climate to volcanic eruptions, extreme events or geoengineering. Here a data-driven approach is introduced based on a dimension reduction, causal reconstruction, and novel network measures based on causal effect theory that go beyond standard complex network tools by distinguishing direct from indirect pathways. Applied to a data set of atmospheric dynamics, the method identifies several strongly uplifting regions acting as major gateways of perturbations spreading in the atmosphere. Additionally, the method provides a stricter statistical approach to pathways of atmospheric teleconnections, yielding insights into the Pacific-Indian Ocean interaction relevant for monsoonal dynamics. Also for neuroscience or power grids, the novel causal interaction perspective provides a complementary approach to simulations or experiments for understanding the functioning of complex spatio-temporal systems with potential applications in increasing their resilience to shocks or extreme events.

  14. Dielectric studies on struvite urinary crystals, a gateway to the new treatment modality for urolithiasis

    NASA Astrophysics Data System (ADS)

    Rajan, Reshma; Raj, N. Arunai Nambi; Madeswaran, S.; Babu, D. Rajan

    2015-09-01

    Struvite or magnesium ammonium phosphate hexahydrate (MAPH) are biological crystals, found in the kidney, which are formed due to the infection caused by urea splitting bacteria in the urinary tract. The struvite crystals observe different morphologies and were developed using single diffusion gel growth technique. The crystalline nature and its composition were studied from different characterization techniques like X-ray Diffraction (XRD) and FTIR. The dielectric behavior of the developed crystal was studied by varying temperature and at different frequencies. The parameters like dielectric constant, dielectric loss, ac conductivity, ac resistivity, impedance and admittance of the struvite crystals were calculated. The studies proved that the dielectric loss or dissipation heat is high in lower frequencies at normal body temperature, which develops a plasma state in the stones and in turn leads to the disintegration of urinary stones. The dielectric nature of the stones leads to the dielectric therapy, which will be a gateway for future treatment modality for urolithiasis.

  15. Finding new superconductors: the spin-fluctuation gateway to high Tc and possible room temperature superconductivity.

    PubMed

    Pines, David

    2013-10-24

    We propose an experiment-based strategy for finding new high transition temperature superconductors that is based on the well-established spin fluctuation magnetic gateway to superconductivity in which the attractive quasiparticle interaction needed for superconductivity comes from their coupling to dynamical spin fluctuations originating in the proximity of the material to an antiferromagnetic state. We show how lessons learned by combining the results of almost three decades of intensive experimental and theoretical study of the cuprates with those found in the decade-long study of a strikingly similar family of unconventional heavy electron superconductors, the 115 materials, can prove helpful in carrying out that search. We conclude that, since Tc in these materials scales approximately with the strength of the interaction, J, between the nearest neighbor local moments in their parent antiferromagnetic state, there may not be a magnetic ceiling that would prevent one from discovering a room temperature superconductor.

  16. Gateway-Assisted Retransmission for Lightweight and Reliable IoT Communications.

    PubMed

    Chang, Hui-Ling; Wang, Cheng-Gang; Wu, Mong-Ting; Tsai, Meng-Hsun; Lin, Chia-Ying

    2016-09-22

    Message Queuing Telemetry Transport for Sensor Networks (MQTT-SN) and Constrained Application Protocol (CoAP) are two protocols supporting publish/subscribe models for IoT devices to publish messages to interested subscribers. Retransmission mechanisms are introduced to compensate for the lack of data reliability. If the device does not receive the acknowledgement (ACK) before retransmission timeout (RTO) expires, the device will retransmit data. Setting an appropriate RTO is important because the delay may be large or retransmission may be too frequent when the RTO is inappropriate. We propose a Gateway-assisted CoAP (GaCoAP) to dynamically compute RTO for devices. Simulation models are proposed to investigate the performance of GaCoAP compared with four other methods. The experiment results show that GaCoAP is more suitable for IoT devices.

  17. Gateway to understanding: Indigenous ecological activism and education in urban, rural, and remote contexts

    NASA Astrophysics Data System (ADS)

    Lowan-Trudeau, Gregory

    2016-08-01

    This article is a response to Kassam, Avery, and Ruelle's insights as presented in this forum on rural science education. Topics considered include troubling the urban/rural divide in the context of Indigenous knowledge and expanding to include the common Canadian notion of the "remote", a designation rooted in our national colonial narrative for the mythic, typically northern, wilderness sparsely inhabited by primarily Indigenous peoples. These concepts are further considered through exploration of Indigenous and allied ecological activism in Canada and the United States related to the proposed Northern Gateway and Keystone XL pipelines. This discussion concludes with an argument for the inherent pedagogical opportunity presented by such cases for contemporary educators to engage students in consideration of wicked problems, geographically rooted cognitive diversity, and the legal, economic, ecological, and cultural underpinnings and ramifications of the current events prominent in their home communities and abroad.

  18. Space Weather data processing and Science Gateway for the Van Allen Probes

    NASA Astrophysics Data System (ADS)

    Romeo, G.; Barnes, R. J.; Weiss, M.; Fox, N. J.; Mauk, B.; Potter, M.; Kessel, R.

    2013-12-01

    A near real-time data processing pipeline for the Space Weather broadcast data from the Van Allen Probes is presented. The Van Allen Probes broadcasts a sub-set of the science data in real-time when not downlinking the principal science data. This broadcast is received by several ground stations and relayed to APL in near real time to be ingested into the space weather processing pipeline. This pipeline processes the available level zero space weather data into higher level science data products. These products are made available to the public via the Van Allen Probes Science Gateway website (http://athena.jhuapl.edu). The website acts as pivotal point though which all other instrument SOC's can be accessed. Several other data products (e.g KP/DST indices) and tools (e.g orbit calculator) are made also available to the general public.

  19. Identifying causal gateways and mediators in complex spatio-temporal systems

    PubMed Central

    Runge, Jakob; Petoukhov, Vladimir; Donges, Jonathan F.; Hlinka, Jaroslav; Jajcay, Nikola; Vejmelka, Martin; Hartman, David; Marwan, Norbert; Paluš, Milan; Kurths, Jürgen

    2015-01-01

    Identifying regions important for spreading and mediating perturbations is crucial to assess the susceptibilities of spatio-temporal complex systems such as the Earth's climate to volcanic eruptions, extreme events or geoengineering. Here a data-driven approach is introduced based on a dimension reduction, causal reconstruction, and novel network measures based on causal effect theory that go beyond standard complex network tools by distinguishing direct from indirect pathways. Applied to a data set of atmospheric dynamics, the method identifies several strongly uplifting regions acting as major gateways of perturbations spreading in the atmosphere. Additionally, the method provides a stricter statistical approach to pathways of atmospheric teleconnections, yielding insights into the Pacific–Indian Ocean interaction relevant for monsoonal dynamics. Also for neuroscience or power grids, the novel causal interaction perspective provides a complementary approach to simulations or experiments for understanding the functioning of complex spatio-temporal systems with potential applications in increasing their resilience to shocks or extreme events. PMID:26443010

  20. Dielectric studies on struvite urinary crystals, a gateway to the new treatment modality for urolithiasis.

    PubMed

    Rajan, Reshma; Raj, N Arunai Nambi; Madeswaran, S; Babu, D Rajan

    2015-09-05

    Struvite or magnesium ammonium phosphate hexahydrate (MAPH) are biological crystals, found in the kidney, which are formed due to the infection caused by urea splitting bacteria in the urinary tract. The struvite crystals observe different morphologies and were developed using single diffusion gel growth technique. The crystalline nature and its composition were studied from different characterization techniques like X-ray Diffraction (XRD) and FTIR. The dielectric behavior of the developed crystal was studied by varying temperature and at different frequencies. The parameters like dielectric constant, dielectric loss, ac conductivity, ac resistivity, impedance and admittance of the struvite crystals were calculated. The studies proved that the dielectric loss or dissipation heat is high in lower frequencies at normal body temperature, which develops a plasma state in the stones and in turn leads to the disintegration of urinary stones. The dielectric nature of the stones leads to the dielectric therapy, which will be a gateway for future treatment modality for urolithiasis.

  1. Note: Methodology for the analysis of Bluetooth gateways in an implemented scatternet

    NASA Astrophysics Data System (ADS)

    Etxaniz, J.; Monje, P. M.; Aranguren, G.

    2014-03-01

    This Note introduces a novel methodology to analyze the time performance of Bluetooth gateways in multi-hop networks, known as scatternets. The methodology is focused on distinguishing between the processing time and the time that each communication between nodes takes along an implemented scatternet. This technique is not only valid for Bluetooth networks but also for other wireless networks that offer access to their middleware in order to include beacons in the operation of the nodes. We show in this Note the results of the tests carried out on a Bluetooth scatternet in order to highlight the reliability and effectiveness of the methodology. The results also validate this technique showing convergence in the results when subtracting the time for the beacons from the delay measurements.

  2. The Weak Stability Boundary, A Gateway for Human Exploration of Space

    NASA Technical Reports Server (NTRS)

    Mendell, Wendell W.

    2000-01-01

    NASA plans for future human exploration of the Solar System describe only missions to Mars. Before such missions can be initiated, much study remains to be done in technology development, mission operations and human performance. While, for example, technology validation and operational experience could be gained in the context of lunar exploration missions, a NASA lunar program is seen as a competitor to a Mars mission rather than a step towards it. The recently characterized Weak Stability Boundary in the Earth-Moon gravitational field may provide an operational approach to all types of planetary exploration, and infrastructure developed for a gateway to the Solar System may be a programmatic solution for exploration that avoids the fractious bickering between Mars and Moon advocates. This viewpoint proposes utilizing the concept of Greater Earth to educate policy makers, opinion makers and the public about these subtle attributes of our space neighborhood.

  3. Two-photon gateway in one-atom cavity quantum electrodynamics.

    PubMed

    Kubanek, A; Ourjoumtsev, A; Schuster, I; Koch, M; Pinkse, P W H; Murr, K; Rempe, G

    2008-11-14

    Single atoms absorb and emit light from a resonant laser beam photon by photon. We show that a single atom strongly coupled to an optical cavity can absorb and emit resonant photons in pairs. The effect is observed in a photon correlation experiment on the light transmitted through the cavity. We find that the atom-cavity system transforms a random stream of input photons into a correlated stream of output photons, thereby acting as a two-photon gateway. The phenomenon has its origin in the quantum anharmonicity of the energy structure of the atom-cavity system. Future applications could include the controlled interaction of two photons by means of one atom.

  4. Gateway to understanding: Indigenous ecological activism and education in urban, rural, and remote contexts

    NASA Astrophysics Data System (ADS)

    Lowan-Trudeau, Gregory

    2017-03-01

    This article is a response to Kassam, Avery, and Ruelle's insights as presented in this forum on rural science education. Topics considered include troubling the urban/rural divide in the context of Indigenous knowledge and expanding to include the common Canadian notion of the "remote", a designation rooted in our national colonial narrative for the mythic, typically northern, wilderness sparsely inhabited by primarily Indigenous peoples. These concepts are further considered through exploration of Indigenous and allied ecological activism in Canada and the United States related to the proposed Northern Gateway and Keystone XL pipelines. This discussion concludes with an argument for the inherent pedagogical opportunity presented by such cases for contemporary educators to engage students in consideration of wicked problems, geographically rooted cognitive diversity, and the legal, economic, ecological, and cultural underpinnings and ramifications of the current events prominent in their home communities and abroad.

  5. Note: Methodology for the analysis of Bluetooth gateways in an implemented scatternet.

    PubMed

    Etxaniz, J; Monje, P M; Aranguren, G

    2014-03-01

    This Note introduces a novel methodology to analyze the time performance of Bluetooth gateways in multi-hop networks, known as scatternets. The methodology is focused on distinguishing between the processing time and the time that each communication between nodes takes along an implemented scatternet. This technique is not only valid for Bluetooth networks but also for other wireless networks that offer access to their middleware in order to include beacons in the operation of the nodes. We show in this Note the results of the tests carried out on a Bluetooth scatternet in order to highlight the reliability and effectiveness of the methodology. The results also validate this technique showing convergence in the results when subtracting the time for the beacons from the delay measurements.

  6. Bipolar Atlantic deepwater circulation in the middle-late Eocene: Effects of Southern Ocean gateway openings

    NASA Astrophysics Data System (ADS)

    Borrelli, Chiara; Cramer, Benjamin S.; Katz, Miriam E.

    2014-04-01

    We present evidence for Antarctic Circumpolar Current (ACC)-like effects on Atlantic deepwater circulation beginning in the late-middle Eocene. Modern ocean circulation is characterized by a thermal differentiation between Southern Ocean and North Atlantic deepwater formation regions. In order to better constrain the timing and nature of the initial thermal differentiation between Northern Component Water (NCW) and Southern Component Water (SCW), we analyze benthic foraminiferal stable isotope (δ18Obf and δ13Cbf) records from Ocean Drilling Program Site 1053 (upper deep water, western North Atlantic). Our data, compared with published records and interpreted in the context of ocean circulation models, indicate that progressive opening of Southern Ocean gateways and initiation of a circum-Antarctic current caused a transition to a modern-like deep ocean circulation characterized by thermal differentiation between SCW and NCW beginning ~38.5 Ma, in the initial stages of Drake Passage opening. In addition, the relatively low δ18Obf values recorded at Site 1053 show that the cooling trend of the middle-late Eocene was not global, because it was not recorded in the North Atlantic. The timing of thermal differentiation shows that NCW contributed to ocean circulation by the late-middle Eocene, ~1-4 Myr earlier than previously thought. We propose that early NCW originated in the Labrador Sea, based on tectonic reconstructions and changes in foraminiferal assemblages in this basin. Finally, we link further development of meridional isotopic gradients in the Atlantic and Pacific in the late Eocene with the Tasman Gateway deepening (~34 Ma) and the consequent development of a circumpolar proto-ACC.

  7. Extending the invitation: Supporting learners from gateway experiences to participating in astronomical research

    NASA Astrophysics Data System (ADS)

    Laurence, Wendi; Gibbs, J.; Marshall, R.; Murphy, M.; Orr, L.; Rebull, L. M.; Whitworth, C.

    2014-01-01

    NITARP provides a forum in which educators conduct authentic astronomical research with guidance from practicing astrophysicists within an interactive professional learning community. As educators learn to conduct astronomical research, they are simultaneously creating educational outreach programs that connect other educators and secondary students to the research process. This means that, at any given time, participants may be learning astronomical content knowledge, field-specific research methodology, computer programs or devising teaching curricula and methods to extend the research experience to others. To support future endeavors, education research methodologies were employed to document the critical junctures where learning might be thwarted (Laurence, Kelley, Becker, Day & Marshall, 2006). These findings benefit the field in general as conducting authentic research is a key initiative in science education. NITARP also fills a unique critical juncture in the astronomical field. While astronomy is often called a gateway science there remains a precipitous drop-off in the number of students or educators who choose to extend their learning beyond planetarium experiences and introductory courses. To provide an invitation into research, and effective support along the way, we asked the question: What supports and cognitive frameworks learners would need to move from observation to research? Our poster will highlight three necessary skill sets: 1) Visualization constructed from multiple sets of data and images to create data driven conclusions; 2) Team research engagement practices, focused on grappling with data that does not have THE answer but rather a series of patterns or comparisons; 3) The use of multiple software programs, trouble shooting and compatibility. Our poster will discuss the teaching challenges and supports we developed to bring students through the research process and widen the gateway to STEM learning. This project was made possible through

  8. How can we build resilience in primary school aged children? The importance of social support from adults and peers in family, school and community settings.

    PubMed

    Stewart, D; Sun, J

    2004-01-01

    This study examines the association between firstly, student resiliency and their perceptions of social support from parents/caregivers, teachers, and peers, and secondly, between student's perception of their general health status and their social support. A cross-sectional research project was designed and conducted in 2003 in an urban and remote area of Queensland, Australia. The study population comprised of 2580 students (Years three, five, and seven) across 20 primary schools. The main outcome measures were self-reported health status and resiliency behaviours. Independent variables included student perceptions of support from parents/caregivers, teachers, school peers, and prosocial groups. Students who perceived parents, teachers, and peers as supportive were more likely to have higher resiliency behaviour in communication and cooperation, self-esteem, empathy, help-seeking, goals and aspirations. Students who considered that their parents, peers at school and prosocial groups were supportive, were more likely to feel healthy. Findings suggest that providing adult and peer support to students at primary school age is a vital strategy in promoting student resiliency and general health for children of primary school age.

  9. A case study of the Secure Anonymous Information Linkage (SAIL) Gateway: a privacy-protecting remote access system for health-related research and evaluation.

    PubMed

    Jones, Kerina H; Ford, David V; Jones, Chris; Dsilva, Rohan; Thompson, Simon; Brooks, Caroline J; Heaven, Martin L; Thayer, Daniel S; McNerney, Cynthia L; Lyons, Ronan A

    2014-08-01

    With the current expansion of data linkage research, the challenge is to find the balance between preserving the privacy of person-level data whilst making these data accessible for use to their full potential. We describe a privacy-protecting safe haven and secure remote access system, referred to as the Secure Anonymised Information Linkage (SAIL) Gateway. The Gateway provides data users with a familiar Windows interface and their usual toolsets to access approved anonymously-linked datasets for research and evaluation. We outline the principles and operating model of the Gateway, the features provided to users within the secure environment, and how we are approaching the challenges of making data safely accessible to increasing numbers of research users. The Gateway represents a powerful analytical environment and has been designed to be scalable and adaptable to meet the needs of the rapidly growing data linkage community.

  10. Public Hearing and Comment Period Documents for the Northeast Gateway Energy Bridge Deepwater, Federal Waters of Massachusetts Bay (Modification to Existing Permit LNG Regasification Vessel/DWP Project)

    EPA Pesticide Factsheets

    List of public hearing & comment period document(s) for the Northeast Gateway Energy Bridge Deepwater Port, Federal Waters of Massachusetts Bay (Modification to Existing Permit LNG Regasification Vessel/DWP Project).

  11. Draft Permit & Supporting Documentation for the Northeast Gateway Energy Bridge Deepwater Port, Federal Waters of Massachusetts Bay (Modification to Existing Permit LNG Regasification Vessel/DWP Project)

    EPA Pesticide Factsheets

    List of draft permit & supporting documentation for the Northeast Gateway Energy Bridge Deepwater Port, Federal Waters of Massachusetts Bay (Modification to Existing Permit LNG Regasification Vessel/DWP Project).

  12. Building Skills to Build Communities

    ERIC Educational Resources Information Center

    Russell, Geoff

    2011-01-01

    Communities are at the heart of the government's vision for the Big Society. And it's the author's strongly held view that skills should be at the heart of each and every one of those communities. If one grows the skills of an individual then the community will flourish. There is a job to be done in building skills to build communities--skilled…

  13. Glacial induced closure of the Panamanian Gateway during Marine Isotope Stages (MIS) 95-100 (∼2.5 Ma)

    NASA Astrophysics Data System (ADS)

    Groeneveld, J.; Hathorne, E. C.; Steinke, S.; DeBey, H.; Mackensen, A.; Tiedemann, R.

    2014-10-01

    The final phase of the closure of the Panamanian Gateway and the intensification of Northern Hemisphere Glaciation (NHG) both occurred during the Late Pliocene. Glacial-interglacial (G-IG) variations in sea level might, therefore, have had a significant impact on the remaining connections between the East Pacific and the Caribbean. Here, we present combined foraminiferal Mg/Ca and δ18O measurements from Ocean Drilling Program (ODP) Site 1241 from the East Pacific and ODP Site 999 from the Caribbean. The studied time interval covers the first three major G-IG Marine Isotope Stages (MIS 95-100, ∼2.5 Ma) after the intensification of NHG. Analyses were performed on the planktonic foraminifera Neogloboquadrina dutertrei and Globigerinoides sacculifer, representing water mass properties in the thermocline and the mixed-layer, respectively. Changes in sea water temperature, relative salinity, and water column stratification strongly suggest that the Panamanian Gateway temporarily closed during glacial MIS 98 and 100, as a result of changes in ice volume equivalent to a drop in sea level of 60-90 m. Reconstructed sea surface temperatures (SST) from G. sacculifer show a glacial decrease of 2.5 °C at Site 1241, but increases of up to 3 °C at Site 999 during glacial MIS 98 and 100 suggesting that the Panamanian Gateway closed during these glacial periods. The Mg/Ca-temperatures of N. dutertrei remain relatively stable in the East Pacific, but do show a 3 °C warming in the Caribbean at the onset of these glacial periods suggesting that the closing of the gateway also changed the water column stratification. We infer that the glacial closure of the gateway allowed the Western Atlantic Warm Pool to extend into the southern Caribbean, increasing SST (G. sacculifer) and deepening the thermocline (N. dutertrei). Additionally, ice volume appears to have become large enough during MIS 100 to survive the relatively short lasting interglacial MIS 99 so that the gateway remained

  14. Building Languages

    MedlinePlus

    ... Communication programs use some form of Simultaneous Communication (speaking and signing at the same time). This program includes building blocks such as Conceptually Accurate Signed English (CASE), Finger Spelling, Listening, Manually Coded English (MCE), ...

  15. The Decahedrella-event in ODP Hole 909C - Implications for Miocene stratigraphic and paleoclimatic interpretations across the Fram Strait gateway

    NASA Astrophysics Data System (ADS)

    Schreck, Michael; Nam, Seung-il; Matthiessen, Jens

    2014-05-01

    ODP Hole 909C has been drilled during ODP Leg 151 in 1993 on a small abyssal terrace located immediately to the North of Hovgaard Ridge within the Fram Strait. This major arctic gateway constitutes the only deep-water connection between the Arctic Ocean and the North Atlantic. Moreover, it serves as a pathway for warmer North Atlantic surface waters entering the Central Arctic, and for colder, sea-ice covered waters that are exported to the south. Therefore the Fram Strait is of crucial importance for global ocean circulation and hence climate. Therefore, this deep-water location was designed by ODP to document the timing of the opening of Fram Strait, and to monitor the Cenozoic evolution of water mass exchange as well as the glacial history and climatic variability in a region critical for understanding Miocene climate evolution. The age model of ODP Hole 909C is primarily based on the interpretation of the magnetic polarity record obtained during the ODP Leg 151 cruise, and provides significant temporal constraints only for the uppermost 40 mbsf, whereas limited recovery and the uncertain occurrence of hiatuses resulted in decreasing reliability of the magnetostratigraphic interpretations downcore and widely divergent hypothesis below 200 mbsf. Two possible correlations of the magnetic signal to the global polarity timescale have been proposed, both neither unique nor definitive, and in the absence of any additional independent age control it is difficult to distinguish between the two models, which in turn seriously hampers reliable paleoenvironmental reconstructions in the Neogene of the gateway region. A detailed palynological study on a paleoenvironmental transect across Fram Strait comprising IODP Site M2 (Central Arctic Ocean), ODP Site 909 (Fram Strait), and ODP Site 907 (Iceland Sea) revealed the presence of a significant acme of the endemic high-latitude acritarch Decahedrella martinheadii at all three sites. Comparable high abundances of this cold

  16. The Decahedrella-event in ODP Hole 909C - Implications for Miocene stratigraphic and paleoclimatic interpretations across the Fram Strait gateway

    NASA Astrophysics Data System (ADS)

    Schreck, M.; Nam, S.; Matthiessen, J. J.

    2013-12-01

    ODP Hole 909C has been drilled during ODP Leg 151 in 1993 on a small abyssal terrace located immediately to the North of Hovgaard Ridge within the Fram Strait. This major arctic gateway constitutes the only deep-water connection between the Arctic Ocean and the North Atlantic. Moreover, it serves as a pathway for warmer North Atlantic surface waters entering the Central Arctic, and for colder, sea-ice covered waters that are exported to the south. Therefore the Fram Strait is of crucial importance for global ocean circulation and hence climate. This deep-water location was designed by ODP to document the timing of the opening of Fram Strait, and to monitor the Cenozoic evolution of water mass exchange as well as the glacial history and climatic variability in a region critical for understanding Miocene climate evolution. The age model of ODP Hole 909C is primarily based on the interpretation of the magnetic polarity record obtained during the ODP Leg 151 cruise, and provides significant temporal constraints only for the uppermost 40 mbsf, whereas limited recovery and the uncertain occurrence of hiatuses resulted in decreasing reliability of the magnetostratigraphic interpretations downcore and widely divergent hypothesis below 200 mbsf. Two possible correlations of the magnetic signal to the global polarity timescale have been proposed, both neither unique nor definitive, and in the absence of any additional independent age control it is difficult to distinguish between the two models, which in turn seriously hampers reliable paleoenvironmental reconstructions in the Neogene of the gateway region. A detailed palynological study on a paleoenvironmental transect across Fram Strait comprising IODP Site M2 (Central Arctic Ocean), ODP Site 909 (Fram Strait), and ODP Site 907 (Iceland Sea) revealed the presence of a significant acme of the endemic high-latitude acritarch Decahedrella martinheadii at all three sites. Comparable high abundances of this cold-water acritarch

  17. Steppingstone and Gateway Ideas: A Discussion of Origins, Research Challenges, and Promising Lines of Research for the Future

    PubMed Central

    Anthony, James C. (Jim)

    2016-01-01

    In this discussion of contributed papers for the special issue of DAD, the author draws attention to early American laws concerning cannabis and to statements made about the epidemiology of cannabis smoking and other drug use between 1858 and the contemporary scene, with coverage of opium, heroin, tobacco, alcohol, cocaine, kava, and other drugs. He discusses these steppingstone and gateway processes in relation to political environment and in relation to scientific challenges such as uncontrolled confounding. He provides a critique of between-individual research designs, including co-twin and co-sib designs of behavior genetics, as well as imaging research, where uncontrolled confounding often exists. He highlights the epidemiologic case-crossover design and prevention research experiments as potentially valuable approaches in new directions for research on the steppingstone and gateway processes. PMID:22572210

  18. A MultiSite Gateway Toolkit for Rapid Cloning of Vertebrate Expression Constructs with Diverse Research Applications

    PubMed Central

    Fowler, Daniel K.; Stewart, Scott; Seredick, Steve; Eisen, Judith S.

    2016-01-01

    Recombination-based cloning is a quick and efficient way to generate expression vectors. Recent advancements have provided powerful recombinant DNA methods for molecular manipulations. Here, we describe a novel collection of three-fragment MultiSite Gateway cloning system-compatible vectors providing expanded molecular tools for vertebrate research. The components of this toolkit encompass a broad range of uses such as fluorescent imaging, dual gene expression, RNA interference, tandem affinity purification, chemically-inducible dimerization and lentiviral production. We demonstrate examples highlighting the utility of this toolkit for producing multi-component vertebrate expression vectors with diverse primary research applications. The vectors presented here are compatible with other Gateway toolkits and collections, facilitating the rapid generation of a broad range of innovative DNA constructs for biological research. PMID:27500400

  19. Our Buildings, Ourselves.

    ERIC Educational Resources Information Center

    Roodman, David Malin; Lenssen, Nicholas

    1994-01-01

    Reviews in detail environmental impacts associated with buildings. Discusses building construction, internal environments, building life spans, building materials, protection from climate, and amenities. (LZ)

  20. Photovoltaic Performance and Reliability Database: A Gateway to Experimental Data Monitoring Projects for PV at the Florida Solar Energy Center

    DOE Data Explorer

    This site is the gateway to experimental data monitoring projects for photovoltaic (PV) at the Florida Solar Energy Center. The website and the database were designed to facilitate and standardize the processes for archiving, analyzing and accessing data collected from dozens of operational PV systems and test facilities monitored by FSEC's Photovoltaics and Distributed Generation Division. [copied from http://www.fsec.ucf.edu/en/research/photovoltaics/data_monitoring/index.htm

  1. To build capacity, build confidence

    NASA Astrophysics Data System (ADS)

    Hewitson, Bruce

    2015-07-01

    The history of attempts to spread scientific know-how beyond western centres of excellence is littered with failures. Capacity building needs long-term commitment, a critical mass of trainees, and a supportive home environment.

  2. The Climate-G Portal: a Grid Enabled Scientifc Gateway for Climate Change

    NASA Astrophysics Data System (ADS)

    Fiore, Sandro; Negro, Alessandro; Aloisio, Giovanni

    2010-05-01

    Grid portals are web gateways aiming at concealing the underlying infrastructure through a pervasive, transparent, user-friendly, ubiquitous and seamless access to heterogeneous and geographical spread resources (i.e. storage, computational facilities, services, sensors, network, databases). Definitively they provide an enhanced problem-solving environment able to deal with modern, large scale scientific and engineering problems. Scientific gateways are able to introduce a revolution in the way scientists and researchers organize and carry out their activities. Access to distributed resources, complex workflow capabilities, and community-oriented functionalities are just some of the features that can be provided by such a web-based environment. In the context of the EGEE NA4 Earth Science Cluster, Climate-G is a distributed testbed focusing on climate change research topics. The Euro-Mediterranean Center for Climate Change (CMCC) is actively participating in the testbed providing the scientific gateway (Climate-G Portal) to access to the entire infrastructure. The Climate-G Portal has to face important and critical challenges as well as has to satisfy and address key requirements. In the following, the most relevant ones are presented and discussed. Transparency: the portal has to provide a transparent access to the underlying infrastructure preventing users from dealing with low level details and the complexity of a distributed grid environment. Security: users must be authenticated and authorized on the portal to access and exploit portal functionalities. A wide set of roles is needed to clearly assign the proper one to each user. The access to the computational grid must be completely secured, since the target infrastructure to run jobs is a production grid environment. A security infrastructure (based on X509v3 digital certificates) is strongly needed. Pervasivity and ubiquity: the access to the system must be pervasive and ubiquitous. This is easily true due

  3. The VERCE platform: Enabling Computational Seismology via Streaming Workflows and Science Gateways

    NASA Astrophysics Data System (ADS)

    Spinuso, Alessandro; Filgueira, Rosa; Krause, Amrey; Matser, Jonas; Casarotti, Emanuele; Magnoni, Federica; Gemund, Andre; Frobert, Laurent; Krischer, Lion; Atkinson, Malcolm

    2015-04-01

    The VERCE project is creating an e-Science platform to facilitate innovative data analysis and coding methods that fully exploit the wealth of data in global seismology. One of the technologies developed within the project is the Dispel4Py python library, which allows to describe abstract stream-based workflows for data-intensive applications and to execute them in a distributed environment. At runtime Dispel4Py is able to map workflow descriptions dynamically onto a number of computational resources (Apache Storm clusters, MPI powered clusters, and shared-memory multi-core machines, single-core machines), setting it apart from other workflow frameworks. Therefore, Dispel4Py enables scientists to focus on their computation instead of being distracted by details of the computing infrastructure they use. Among the workflows developed with Dispel4Py in VERCE, we mention here those for Seismic Ambient Noise Cross-Correlation and MISFIT calculation, which address two data-intensive problems that are common in computational seismology. The former, also called Passive Imaging, allows the detection of relative seismic-wave velocity variations during the time of recording, to be associated with the stress-field changes that occurred in the test area. The MISFIT instead, takes as input the synthetic seismograms generated from HPC simulations for a certain Earth model and earthquake and, after a preprocessing stage, compares them with real observations in order to foster subsequent model updates and improvement (Inversion). The VERCE Science Gateway exposes the MISFIT calculation workflow as a service, in combination with the simulation phase. Both phases can be configured, controlled and monitored by the user via a rich user interface which is integrated within the gUSE Science Gateway framework, hiding the complexity of accessing third parties data services, security mechanisms and enactment on the target resources. Thanks to a modular extension to the Dispel4Py framework

  4. Treatment of symptomatic intracranial atherosclerotic stenosis with a normal-sized Gateway(™) balloon and Wingspan(™) stent.

    PubMed

    Yu, J; Wang, L; Deng, J P; Gao, L; Zhang, T; Zhao, Z W; Gao, G D

    2010-01-01

    The safety and performance of angioplasty using a normal-sized Gateway(™) balloon and Wingspan(™) stent for intracranial atherosclerotic stenosis were assessed. Seventy-two patients with intracranial stenosis (≥ 50%) were treated using an undersized (group U) or normal-sized (group N) Gateway(™) balloon and a Wingspan(™) stent. All patients were successfully stented. Stenosis improved from 74.2% before treatment to 23.8% immediately after treatment in group U and from 70.9% to 20.1% in group N. The two groups had similar rates of major periprocedural neurological complications (9.0% overall), none of which led to death. Residual stenosis at follow-up was 40.8% and 32.5% in groups U and N, respectively. In-stent re-stenosis (ISR) was significantly less frequent in group N (22.0%) than in group U (33.3%). It is concluded that use of a normal-sized Gateway(™) balloon and Wingspan(™) stent appears to be safe, to have a high rate of technical success, good immediate post-operative results and a low ISR rate.

  5. The Climate-G Portal: a scientific gateway for climate change

    NASA Astrophysics Data System (ADS)

    Fiore, S.; Aloisio, G.; Blower, J. D.; Cofino, A.; Denvil, S.; Fox, P. A.; Petitdidier, M.; Schwichtenberg, H.

    2010-12-01

    Climate-G is a data-oriented research effort conceived in the context of the EGEE Earth Science Cluster and devoted to the Climate Change community. The testbed is an interdisciplinary effort joining expertise in the field of climate change and computational science. The main goal of Climate-G is to allow scientists carrying out geographical and cross-institutional data discovery, access, visualization and sharing of climate data. The involved partners are: Centro Euro-Mediterraneo per i Cambiamenti Climatici (CMCC, Italy), Institut Pierre-Simon Laplace (IPSL/CNRS, France), Fraunhofer Institut für Algorithmen und Wissenschaftliches Rechnen (SCAI, Germany), National Center for Atmospheric Research (NCAR, USA) and Rensselaer Polytechnic Institute (RPI, USA), University of Reading (Reading, UK), University of Cantabria (UC, Spain), and University of Salento (UniSalento, Italy). The main results of this testbed are the distributed data/metadata architecture (exploiting the GRelC service) and the scientific gateway of the testbed (Climate-G Portal). The latter is a central topic of this contribution. Data distribution comes from the need of sharing data among centres without moving it into a central repository. Each partner can contribute with new datasets to the testbed just adding a new data service into the infrastructure and mapping it on a specific metadata server. The metadata management plays a critical role in such a distributed environment, since it enables search and discovery activities, allows describing and cataloguing datasets, makes data effectively accessible and shareable by the scientific community. The novel grid enabled harvesting system will be presented and discussed showing a map-enabled search page providing aggregated metadata information. Climate-G exploits both grid technologies connected with the EGEE project and domain-based tools and services. The general grid services provide a solid basis at an infrastructural level ensuring great

  6. A Split-GFP Gateway Cloning System for Topology Analyses of Membrane Proteins in Plants

    PubMed Central

    Xie, Wenjun; Nielsen, Mads Eggert; Pedersen, Carsten

    2017-01-01

    To understand the function of membrane proteins, it is imperative to know their topology. For such studies, a split green fluorescent protein (GFP) method is useful. GFP is barrel-shaped, consisting of 11 β-sheets. When the first ten β-sheets (GFP1-10) and the 11th β-sheet (GFP11) are expressed from separate genes they will self-assembly and reconstitute a fluorescent GFP protein. However, this will only occur when the two domains co-localize in the same cellular compartment. We have developed an easy-to-use Gateway vector set for determining on which side of the membrane the N- and C-termini are located. Two vectors were designed for making N- and C-terminal fusions between the membrane proteins-of-interest and GFP11, while another three plasmids were designed to express GFP1-10 in either the cytosol, the endoplasmic reticulum (ER) lumen or the apoplast. We tested functionality of the system by applying the vector set for the transmembrane domain, CNXTM, of the ER membrane protein, calnexin, after transient expression in Nicotiana benthamiana leaves. We observed GFP signal from the ER when we reciprocally co-expressed GFP11-CNXTM with GFP1-10-HDEL and CNXTM-GFP with cytosolic GFP1-10. The opposite combinations did not result in GFP signal emission. This test using the calnexin ER-membrane domain demonstrated its C-terminus to be in the cytosol and its N-terminus in the ER lumen. This result confirmed the known topology of calnexin, and we therefore consider this split-GFP system highly useful for ER membrane topology studies. Furthermore, the vector set provided is useful for detecting the topology of proteins on other membranes in the cell, which we confirmed for a plasma membrane syntaxin. The set of five Ti-plasmids are easily and efficiently used for Gateway cloning and transient transformation of N. benthamiana leaves. PMID:28085941

  7. NASA's Earth Science Gateway: A Platform for Interoperable Services in Support of the GEOSS Architecture

    NASA Astrophysics Data System (ADS)

    Alameh, N.; Bambacus, M.; Cole, M.

    2006-12-01

    Nasa's Earth Science as well as interdisciplinary research and applications activities require access to earth observations, analytical models and specialized tools and services, from diverse distributed sources. Interoperability and open standards for geospatial data access and processing greatly facilitate such access among the information and processing compo¬nents related to space¬craft, airborne, and in situ sensors; predictive models; and decision support tools. To support this mission, NASA's Geosciences Interoperability Office (GIO) has been developing the Earth Science Gateway (ESG; online at http://esg.gsfc.nasa.gov) by adapting and deploying a standards-based commercial product. Thanks to extensive use of open standards, ESG can tap into a wide array of online data services, serve a variety of audiences and purposes, and adapt to technology and business changes. Most importantly, the use of open standards allow ESG to function as a platform within a larger context of distributed geoscience processing, such as the Global Earth Observing System of Systems (GEOSS). ESG shares the goals of GEOSS to ensure that observations and products shared by users will be accessible, comparable, and understandable by relying on common standards and adaptation to user needs. By maximizing interoperability, modularity, extensibility and scalability, ESG's architecture fully supports the stated goals of GEOSS. As such, ESG's role extends beyond that of a gateway to NASA science data to become a shared platform that can be leveraged by GEOSS via: A modular and extensible architecture Consensus and community-based standards (e.g. ISO and OGC standards) A variety of clients and visualization techniques, including WorldWind and Google Earth A variety of services (including catalogs) with standard interfaces Data integration and interoperability Mechanisms for user involvement and collaboration Mechanisms for supporting interdisciplinary and domain-specific applications ESG

  8. Molecular mechanism for a gateway drug: epigenetic changes initiated by nicotine prime gene expression by cocaine.

    PubMed

    Levine, Amir; Huang, Yanyou; Drisaldi, Bettina; Griffin, Edmund A; Pollak, Daniela D; Xu, Shiqin; Yin, Deqi; Schaffran, Christine; Kandel, Denise B; Kandel, Eric R

    2011-11-02

    In human populations, cigarettes and alcohol generally serve as gateway drugs, which people use first before progressing to marijuana, cocaine, or other illicit substances. To understand the biological basis of the gateway sequence of drug use, we developed an animal model in mice and used it to study the effects of nicotine on subsequent responses to cocaine. We found that pretreatment of mice with nicotine increased the response to cocaine, as assessed by addiction-related behaviors and synaptic plasticity in the striatum, a brain region critical for addiction-related reward. Locomotor sensitization was increased by 98%, conditioned place preference was increased by 78%, and cocaine-induced reduction in long-term potentiation (LTP) was enhanced by 24%. The responses to cocaine were altered only when nicotine was administered first, and nicotine and cocaine were then administered concurrently. Reversing the order of drug administration was ineffective; cocaine had no effect on nicotine-induced behaviors and synaptic plasticity. Nicotine primed the response to cocaine by enhancing its ability to induce transcriptional activation of the FosB gene through inhibition of histone deacetylase, which caused global histone acetylation in the striatum. We tested this conclusion further and found that a histone deacetylase inhibitor simulated the actions of nicotine by priming the response to cocaine and enhancing FosB gene expression and LTP depression in the nucleus accumbens. Conversely, in a genetic mouse model characterized by reduced histone acetylation, the effects of cocaine on LTP were diminished. We achieved a similar effect by infusing a low dose of theophylline, an activator of histone deacetylase, into the nucleus accumbens. These results from mice prompted an analysis of epidemiological data, which indicated that most cocaine users initiate cocaine use after the onset of smoking and while actively still smoking, and that initiating cocaine use after smoking

  9. Contourite drift evolution and related coral growth in the eastern Gulf of Mexico and its gateways

    NASA Astrophysics Data System (ADS)

    Hübscher, Christian; Dullo, Christian; Flögel, Sascha; Titschack, Jürgen; Schönfeld, Joachim

    2010-10-01

    Sediment subbottom profiler and multi-beam data reveal that sediment drifts evolved in various depth intervals between 420 and 650 m water depth in the eastern Golf of Mexico and its gateways. Drift evolution on the western flank of the Yucatan Strait is controlled by the northbound Loop Current down to 800 m and by a counter-current beneath. On the northern Campeche Bank and the West Florida Slope, drifts evolved in depth of 520-600 m and 420-550 m, respectively. In both instances, the causative contour current represents a counter flow to the Loop Current. The varying depth ranges correlate with an eastward rise of the upper boundary of the Antarctic Intermediate Water. The geometry and reflection pattern of upper slope deposits strongly suggest that the causative bottom current velocities in the eastern Gulf of Mexico varied significantly in space and time. The subbottom profiler data further show peculiar stacked diffraction hyperbolae in depths between 480 and 600 m. Camera and video observations from the seafloor off western Florida imply that the diffraction hyperbolas are formed by boulders and cliffs of sedimentary rock, which are locally colonized by cold-water corals, such as Lophelia pertusa, octocorals and stylasterids.

  10. The sources of atmospheric black carbon at a European gateway to the Arctic.

    PubMed

    Winiger, P; Andersson, A; Eckhardt, S; Stohl, A; Gustafsson, Ö

    2016-09-15

    Black carbon (BC) aerosols from incomplete combustion of biomass and fossil fuel contribute to Arctic climate warming. Models-seeking to advise mitigation policy-are challenged in reproducing observations of seasonally varying BC concentrations in the Arctic air. Here we compare year-round observations of BC and its δ(13)C/Δ(14)C-diagnosed sources in Arctic Scandinavia, with tailored simulations from an atmospheric transport model. The model predictions for this European gateway to the Arctic are greatly improved when the emission inventory of anthropogenic sources is amended by satellite-derived estimates of BC emissions from fires. Both BC concentrations (R(2)=0.89, P<0.05) and source contributions (R(2)=0.77, P<0.05) are accurately mimicked and linked to predominantly European emissions. This improved model skill allows for more accurate assessment of sources and effects of BC in the Arctic, and a more credible scientific underpinning of policy efforts aimed at efficiently reducing BC emissions reaching the European Arctic.

  11. Healthcare Data Gateways: Found Healthcare Intelligence on Blockchain with Novel Privacy Risk Control.

    PubMed

    Yue, Xiao; Wang, Huiju; Jin, Dawei; Li, Mingqiang; Jiang, Wei

    2016-10-01

    Healthcare data are a valuable source of healthcare intelligence. Sharing of healthcare data is one essential step to make healthcare system smarter and improve the quality of healthcare service. Healthcare data, one personal asset of patient, should be owned and controlled by patient, instead of being scattered in different healthcare systems, which prevents data sharing and puts patient privacy at risks. Blockchain is demonstrated in the financial field that trusted, auditable computing is possible using a decentralized network of peers accompanied by a public ledger. In this paper, we proposed an App (called Healthcare Data Gateway (HGD)) architecture based on blockchain to enable patient to own, control and share their own data easily and securely without violating privacy, which provides a new potential way to improve the intelligence of healthcare systems while keeping patient data private. Our proposed purpose-centric access model ensures patient own and control their healthcare data; simple unified Indicator-Centric Schema (ICS) makes it possible to organize all kinds of personal healthcare data practically and easily. We also point out that MPC (Secure Multi-Party Computing) is one promising solution to enable untrusted third-party to conduct computation over patient data without violating privacy.

  12. Protecting Place Through Community Alliances: Haida Gwaii Responds to the Proposed Enbridge Northern Gateway Project

    NASA Astrophysics Data System (ADS)

    Crist, Valine

    This research contributes to the emerging dialogue concerning power relationships and the alliances that are challenging current frameworks in an attempt to create positive change. Worldwide, local people in rural places are threatened by development paradigms and conflicting social, political, economic, and ecological values. Large-scale development, such as the Enbridge Northern Gateway Project (NGP), provide a tangible example of our failing systems and make the interplay of these elements palpable. Increasingly, communities are coalescing to challenge the current models and economically motivated agendas threatening Indigenous sovereignty and local lifeways. Central to these coalitions are Indigenous peoples who are aligning with non-Indigenous neighbours to renegotiate power relationships. This research examines these dynamic alliances and uses Haida Gwaii's resistance to the NGP as an example of the formidable strength of community coalitions mobilized by intersecting values. To contextualize the NGP within the broader discourse, I problematize Canada's environmental assessment process and consider how media portrays the growing resistance to the proposed project. Drawing on information presented through the environmental assessment, I analyze the main messages and shared values of Haida Gwaii citizens opposed to the NGP. This thesis focuses on this unanimous and galvanizing resistance, which is largely motivated by the reliance on local food sources and an embodied connection to Haida Gwaii shared by Island citizens. The continued denial of Aboriginal title and rights was inherent throughout this consideration and is an underlying theme throughout the analyses.

  13. Erysipelothrix rhusiopathiae exploits cytokeratin 18-positive epithelial cells of porcine tonsillar crypts as an invasion gateway.

    PubMed

    Harada, Tomoyuki; Ogawa, Yohsuke; Eguchi, Masahiro; Shi, Fang; Sato, Masumi; Uchida, Kazuyuki; Nakayama, Hiroyuki; Shimoji, Yoshihiro

    2013-06-15

    Tonsils are important organs for mucosal immunity and are gateways for various pathogens, including bacteria and viruses. The purpose of the present study was to reveal how Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas, invades the mucosal epithelium of the tonsils of pigs. Two germ-free piglets were orally infected with E. rhusiopathiae Koganei 65-0.15, an attenuated vaccine strain in Japan, and their tonsils of the soft palate were histologically examined four weeks after infection. Bacterial organisms were observed in dilated crypt lumens and a few epithelial cells of the crypt. Immunohistochemical examination revealed that some epithelial cells of the crypt were positive for cytokeratin (CK) 18, a specific marker for M cells in the Peyer's patches of pigs. Confocal laser scanning microscopy showed that bacterial antigens were present in the cytoplasm of CK 18-positive epithelial cells. Furthermore, an ultramicroscopic examination revealed that the bacteria-containing epithelial cells did not have microfolds or microvilli, both of which are characteristic of membranous epithelial cells (M cells), and that they were in close contact with intraepithelial phagocytes. Thus, the present observations suggest that the tonsillar crypt epithelium is a site of persistent infection for orally administered E. rhusiopathiae, and the bacteria exploit cytokeratin 18-positive epithelial cells of the crypts as portals of entry into the body.

  14. Common liability to addiction and “gateway hypothesis”: Theoretical, empirical and evolutionary perspective

    PubMed Central

    Vanyukov, Michael M.; Tarter, Ralph E.; Kirillova, Galina P.; Kirisci, Levent; Reynolds, Maureen D.; Kreek, Mary Jeanne; Conway, Kevin P.; Maher, Brion S.; Iacono, William G.; Bierut, Laura; Neale, Michael C.; Clark, Duncan B.; Ridenour, Ty A.

    2013-01-01

    Background Two competing concepts address the development of involvement with psychoactive substances: the “gateway hypothesis” (GH) and common liability to addiction (CLA). Method The literature on theoretical foundations and empirical findings related to both concepts is reviewed. Results The data suggest that drug use initiation sequencing, the core GH element, is variable and opportunistic rather than uniform and developmentally deterministic. The association between risks for use of different substances, if any, can be more readily explained by common underpinnings than by specific staging. In contrast, the CLA concept is grounded in genetic theory and supported by data identifying common sources of variation in the risk for specific addictions. This commonality has identifiable neurobiological substrate and plausible evolutionary explanations. Conclusions Whereas the “gateway” hypothesis does not specify mechanistic connections between “stages”, and does not extend to the risks for addictions, the concept of common liability to addictions incorporates sequencing of drug use initiation as well as extends to related addictions and their severity, provides a parsimonious explanation of substance use and addiction co-occurrence, and establishes a theoretical and empirical foundation to research in etiology, quantitative risk and severity measurement, as well as targeted non-drug-specific prevention and early intervention. PMID:22261179

  15. Vaccination of biological cellulose fibers with glucose: a gateway to novel nanocomposites.

    PubMed

    Fahmy, Tamer Y A; Mobarak, Fardous

    2008-01-01

    This work introduces, for the first time worldwide, the means to preserve and protect the natural nanoporous structure of the never-dried plant cell wall, against the irreversible collapse, which occurs due to drying. Simultaneously, these means, used for the above-mentioned aim, provide a gateway to novel nanocomposite materials, which retain the super reactive and super absorbent properties of the never-dried biological cellulose fibers. The present work showed, for the first time worldwide, that glucose can be vaccinated into the cell wall micropores or nanostructure of the never-dried biological cellulose fibers, by simple new techniques, to create a reactive novel nanocomposite material possessing surprising super absorbent properties. Inoculation of the never dried biological cellulose fibers, with glucose, prevented the collapse of the cell wall nanostructure, which normally occurs due to drying. The nanocomposite, produced after drying of the glucose inoculated biological cellulose, retained the super absorbent properties of the never dried biological cellulose fibers. It was found that glucose under certain circumstances grafts to the never dried biological cellulose fibers to form a novel natural nanocomposite material. About 3-8% (w/w) glucose remained grafted in the novel nanocomposite.

  16. Arctic Ecosystem Integrated Survey (Arctic Eis): Marine ecosystem dynamics in the rapidly changing Pacific Arctic Gateway

    NASA Astrophysics Data System (ADS)

    Mueter, Franz J.; Weems, Jared; Farley, Edward V.; Sigler, Michael F.

    2017-01-01

    Arctic Marine Ecosystems are undergoing rapid changes associated with ice loss and surface warming resulting from human activities (IPCC, 2013). The most dramatic changes include an earlier ice retreat and a longer ice-free season, particularly on Arctic inflow shelves such as the Barents Sea in the Atlantic Arctic and the northern Bering Sea and Chukchi Sea in the Pacific Arctic, the two major gateways into the Arctic (Danielson et al., 2016; Frey et al., 2015; Serreze et al., 2007; Wood et al., 2015). The retreat of Arctic sea ice has opened access to the Arctic marine environment and its resources, particularly during summer, and among other changes has brought with it increased research activities. For the Pacific Arctic region, these activities have led to several recent compendiums examining physical, biogeochemical, and biological patterns and trends in this rapidly changing environment (Arrigo, 2015, 2016; Arrigo et al., 2014; Bluhm et al., 2010; Dunton et al., 2014; Grebmeier and Maslowski, 2014; Hopcroft and Day, 2013; Moore and Stabeno, 2015).

  17. Earth science big data at users' fingertips: the EarthServer Science Gateway Mobile

    NASA Astrophysics Data System (ADS)

    Barbera, Roberto; Bruno, Riccardo; Calanducci, Antonio; Fargetta, Marco; Pappalardo, Marco; Rundo, Francesco

    2014-05-01

    The EarthServer project (www.earthserver.eu), funded by the European Commission under its Seventh Framework Program, aims at establishing open access and ad-hoc analytics on extreme-size Earth Science data, based on and extending leading-edge Array Database technology. The core idea is to use database query languages as client/server interface to achieve barrier-free "mix & match" access to multi-source, any-size, multi-dimensional space-time data -- in short: "Big Earth Data Analytics" - based on the open standards of the Open Geospatial Consortium Web Coverage Processing Service (OGC WCPS) and the W3C XQuery. EarthServer combines both, thereby achieving a tight data/metadata integration. Further, the rasdaman Array Database System (www.rasdaman.com) is extended with further space-time coverage data types. On server side, highly effective optimizations - such as parallel and distributed query processing - ensure scalability to Exabyte volumes. In this contribution we will report on the EarthServer Science Gateway Mobile, an app for both iOS and Android-based devices that allows users to seamlessly access some of the EarthServer applications using SAML-based federated authentication and fine-grained authorisation mechanisms.

  18. The sources of atmospheric black carbon at a European gateway to the Arctic

    NASA Astrophysics Data System (ADS)

    Winiger, P.; Andersson, A.; Eckhardt, S.; Stohl, A.; Gustafsson, Ö.

    2016-09-01

    Black carbon (BC) aerosols from incomplete combustion of biomass and fossil fuel contribute to Arctic climate warming. Models--seeking to advise mitigation policy--are challenged in reproducing observations of seasonally varying BC concentrations in the Arctic air. Here we compare year-round observations of BC and its δ13C/Δ14C-diagnosed sources in Arctic Scandinavia, with tailored simulations from an atmospheric transport model. The model predictions for this European gateway to the Arctic are greatly improved when the emission inventory of anthropogenic sources is amended by satellite-derived estimates of BC emissions from fires. Both BC concentrations (R2=0.89, P<0.05) and source contributions (R2=0.77, P<0.05) are accurately mimicked and linked to predominantly European emissions. This improved model skill allows for more accurate assessment of sources and effects of BC in the Arctic, and a more credible scientific underpinning of policy efforts aimed at efficiently reducing BC emissions reaching the European Arctic.

  19. The sources of atmospheric black carbon at a European gateway to the Arctic

    PubMed Central

    Winiger, P; Andersson, A; Eckhardt, S; Stohl, A; Gustafsson, Ö.

    2016-01-01

    Black carbon (BC) aerosols from incomplete combustion of biomass and fossil fuel contribute to Arctic climate warming. Models—seeking to advise mitigation policy—are challenged in reproducing observations of seasonally varying BC concentrations in the Arctic air. Here we compare year-round observations of BC and its δ13C/Δ14C-diagnosed sources in Arctic Scandinavia, with tailored simulations from an atmospheric transport model. The model predictions for this European gateway to the Arctic are greatly improved when the emission inventory of anthropogenic sources is amended by satellite-derived estimates of BC emissions from fires. Both BC concentrations (R2=0.89, P<0.05) and source contributions (R2=0.77, P<0.05) are accurately mimicked and linked to predominantly European emissions. This improved model skill allows for more accurate assessment of sources and effects of BC in the Arctic, and a more credible scientific underpinning of policy efforts aimed at efficiently reducing BC emissions reaching the European Arctic. PMID:27627859

  20. Targeting the SR-B1 Receptor as a Gateway for Cancer Therapy and Imaging

    PubMed Central

    Mooberry, Linda K.; Sabnis, Nirupama A.; Panchoo, Marlyn; Nagarajan, Bhavani; Lacko, Andras G.

    2016-01-01

    Malignant tumors display remarkable heterogeneity to the extent that even at the same tissue site different types of cells with varying genetic background may be found. In contrast, a relatively consistent marker the scavenger receptor type B1 (SR-B1) has been found to be consistently overexpressed by most tumor cells. Scavenger Receptor Class B Type I (SR-BI) is a high density lipoprotein (HDL) receptor that facilitates the uptake of cholesterol esters from circulating lipoproteins. Additional findings suggest a critical role for SR-BI in cholesterol metabolism, signaling, motility, and proliferation of cancer cells and thus a potential major impact in carcinogenesis and metastasis. Recent findings indicate that the level of SR-BI expression correlate with aggressiveness and poor survival in breast and prostate cancer. Moreover, genomic data show that depending on the type of cancer, high or low SR-BI expression may promote poor survival. This review discusses the importance of SR-BI as a diagnostic as well as prognostic indicator of cancer to help elucidate the contributions of this protein to cancer development, progression, and survival. In addition, the SR-B1 receptor has been shown to serve as a potential gateway for the delivery of therapeutic agents when reconstituted high density lipoprotein nanoparticles are used for their transport to cancer cells and tumors. Opportunities for the development of new technologies, particularly in the areas of cancer therapy and tumor imaging are discussed. PMID:28018216

  1. Development of a multipurpose GATEWAY-based lentiviral tetracycline-regulated conditional RNAi system (GLTR).

    PubMed

    Sigl, Reinhard; Ploner, Christian; Shivalingaiah, Giridhar; Kofler, Reinhard; Geley, Stephan

    2014-01-01

    RNA interference (RNAi) has become an essential technology for functional gene analysis. Its success, however, depends on the effective expression of RNAi-inducing small double-stranded interfering RNA molecules (siRNAs) in target cells. In many cell types, RNAi can be achieved by transfection of chemically synthesised siRNAs, which results in transient knockdown of protein expression. Expression of double-stranded short hairpin RNA (shRNA) provides another means to induce RNAi in cells that are hard to transfect. To facilitate the generation of stable, conditional RNAi cell lines, we have developed novel one- and two-component vector GATEWAY-compatible lentiviral tetracycline-regulated RNAi (GLTR) systems. The combination of a modified RNA-polymerase-III-dependent H1 RNA promoter (designated 'THT') for conditional shRNA expression with different lentiviral delivery vectors allows (1) the use of fluorescent proteins for colour-coded combinatorial RNAi or for monitoring RNAi induction (pGLTR-FP), (2) selection of transduced cells (pGLTR-S), and (3) the generation of conditional cell lines using a one vector system (pGLTR-X). All three systems were found to be suitable for the analysis of essential genes, such as CDC27, a component of the mitotic ubiquitin ligase APC/C, in cell lines and primary human cells.

  2. On the Capability of Smartphones to Perform as Communication Gateways in Medical Wireless Personal Area Networks

    PubMed Central

    Morón, María José; Luque, Rafael; Casilari, Eduardo

    2014-01-01

    This paper evaluates and characterizes the technical performance of medical wireless personal area networks (WPANs) that are based on smartphones. For this purpose, a prototype of a health telemonitoring system is presented. The prototype incorporates a commercial Android smartphone, which acts as a relay point, or “gateway”, between a set of wireless medical sensors and a data server. Additionally, the paper investigates if the conventional capabilities of current commercial smartphones can be affected by their use as gateways or “Holters” in health monitoring applications. Specifically, the profiling has focused on the CPU and power consumption of the mobile devices. These metrics have been measured under several test conditions modifying the smartphone model, the type of sensors connected to the WPAN, the employed Bluetooth profile (SPP (serial port profile) or HDP (health device profile)), the use of other peripherals, such as a GPS receiver, the impact of the use of the Wi-Fi interface or the employed method to encode and forward the data that are collected from the sensors. PMID:24451456

  3. A suite of Gateway® compatible ternary expression vectors for functional analysis in Zymoseptoria tritici.

    PubMed

    Sidhu, Y S; Chaudhari, Y K; Usher, J; Cairns, T C; Csukai, M; Haynes, K

    2015-06-01

    Gene overexpression is a widely used functional genomics approach in fungal biology. However, to date it has not been established in Zymoseptoria tritici which is an important pathogen of wheat (Triticum species). Here we report a suite of Gateway® recombination compatible ternary expression vectors for Agrobacterium tumefaciens mediated transformation of Z. tritici. The suite of 32 vectors is based on a combination of four resistance markers for positive selection against glufosinate ammonium, geneticin, hygromycin and sulfonylurea; three constitutive Z. tritici promoters (pZtATUB, pZtGAPDH and pZtTEF) and a nitrogen responsive promoter (pZtNIA1) for controlled expression of the open reading frames. Half of the vectors facilitate expression of proteins tagged with C-terminal EGFP. All 32 vectors allow high frequency targeting of the overexpression cassette into the Ku70 locus and complement the Ku70 gene when transformed into a Z. tritici ku70 null strain, thus circumventing additional phenotypes that can arise from random integration. This suite of ternary expression vectors will be a useful tool for functional analysis through gene overexpression in Z. tritici.

  4. Development of Gateway Binary Vector Series with Four Different Selection Markers for the Liverwort Marchantia polymorpha

    PubMed Central

    Ueda, Minoru; Inoue, Keisuke; Ishida, Sakiko; Nishimura, Yoshiki; Shikanai, Toshiharu; Kohchi, Takayuki

    2015-01-01

    We previously reported Agrobacterium-mediated transformation methods for the liverwort Marchantia polymorpha using the hygromycin phosphotransferase gene as a marker for selection with hygromycin. In this study, we developed three additional markers for M. polymorpha transformation: the gentamicin 3'-acetyltransferase gene for selection with gentamicin; a mutated acetolactate synthase gene for selection with chlorsulfuron; and the neomycin phosphotransferase II gene for selection with G418. Based on these four marker genes, we have constructed a series of Gateway binary vectors designed for transgenic experiments on M. polymorpha. The 35S promoter from cauliflower mosaic virus and endogenous promoters for constitutive and heat-inducible expression were used to create these vectors. The reporters and tags used were Citrine, 3×Citrine, Citrine-NLS, TagRFP, tdTomato, tdTomato-NLS, GR, SRDX, SRDX-GR, GUS, ELuc(PEST), and 3×FLAG. These vectors, designated as the pMpGWB series, will facilitate molecular genetic analyses of the emerging model plant M. polymorpha. PMID:26406247

  5. The Mitochondrial Fission Protein hFis1 Requires the Endoplasmic Reticulum Gateway to Induce Apoptosis

    PubMed Central

    Alirol, Emilie; James, Dominic; Huber, Denise; Marchetto, Andrea; Vergani, Lodovica

    2006-01-01

    Mitochondrial fission ensures organelle inheritance during cell division and participates in apoptosis. The fission protein hFis1 triggers caspase-dependent cell death, by causing the release of cytochrome c from mitochondria. Here we show that mitochondrial fission induced by hFis1 is genetically distinct from apoptosis. In cells lacking the multidomain proapoptotic Bcl-2 family members Bax and Bak (DKO), hFis1 caused mitochondrial fragmentation but not organelle dysfunction and apoptosis. Similarly, a mutant in the intermembrane region of hFis1-induced fission but not cell death, further dissociating mitochondrial fragmentation from apoptosis induction. Selective correction of the endoplasmic reticulum (ER) defect of DKO cells restored killing by hFis1, indicating that death by hFis1 relies on the ER gateway of apoptosis. Consistently, hFis1 did not directly activate BAX and BAK, but induced Ca2+-dependent mitochondrial dysfunction. Thus, hFis1 is a bifunctional protein that independently regulates mitochondrial fragmentation and ER-mediated apoptosis. PMID:16914522

  6. Building Trades.

    ERIC Educational Resources Information Center

    Gudzak, Raymond

    This curriculum guide provides materials for a competency-based course in building trades at the secondary level. The curriculum design uses the curriculum infused model for the teaching of basic skills as part of vocational education and demonstrates the relationship of vocationally related skills to communication, mathematics, and science…

  7. Team building

    SciTech Connect

    Kane, C.

    1993-04-01

    Power plants are particularly complicated projects with abundant opportunities for disputes. Efforts are beginning in the power industry to change the way the industry does business. Key elements of a comprehensive team-building approach include partnering, constructability, use of incentives, and the disputes review board.

  8. Building Sinusoids

    ERIC Educational Resources Information Center

    Landers, Mara G.

    2013-01-01

    In this article, the author describes the development and implementation of a measurement-based group activity designed to support students in understanding the connection between angle magnitude and the shape of the sine function. She explains that the benefit of this activity is that it allows students to build their trigonometric knowledge…

  9. Prioritizing Alcohol Prevention: Establishing Alcohol as the Gateway Drug and Linking Age of First Drink with Illicit Drug Use

    ERIC Educational Resources Information Center

    Barry, Adam E.; King, Jessica; Sears, Cynthia; Harville, Cedric; Bondoc, Irina; Joseph, Kessy

    2016-01-01

    Background: Given ever-reducing budgets of community and school substance use prevention programs, there is a call for identifying the first substance in the sequence leading to polydrug use. Methods: Examining data from a nationally representative sample of 2835 United States 12th graders, we sought to determine (1) the first substance…

  10. Building No. 5, Main Building; Building NO. 9, Guard House ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Building No. 5, Main Building; Building NO. 9, Guard House (left). Viewed from across corner Lakeside Avenue and Main Street - Thomas A. Edison Laboratories, Main Street & Lakeside Avenue, West Orange, Essex County, NJ

  11. 2. PRINTING AND ADVERTISING BUILDING, ADMINISTRATION BUILDING, MERCHANDISE BUILDING, AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. PRINTING AND ADVERTISING BUILDING, ADMINISTRATION BUILDING, MERCHANDISE BUILDING, AND GARDEN, VIEW TO SOUTHWEST - Sears Roebuck & Company Mail Order Plant, Bounded by Lexington & Grenshaw Streets, Kedzie Avenue & Independence Boulevard, Chicago, Cook County, IL

  12. Energy conservation in large buildings

    NASA Astrophysics Data System (ADS)

    Rosenfeld, A.; Hafemeister, D.

    1985-11-01

    As energy prices rise, newly energy aware designers use better tools and technology to create energy efficient buildings. Thus the U.S. office stock (average age 20 years) uses 250 kBTU/ft2 of resource energy, but the guzzler of 1972 uses 500 (up×2), and the 1986 ASHRAE standards call for 100-125 (less than 25% of their 1972 ancestors). Surprisingly, the first real cost of these efficient buildings has not risen since 1972. Scaling laws are used to calculate heat gains and losses of buildings to obtain the ΔT(free) which can be as large as 15-30 °C (30-60 °F) for large buildings. The net thermal demand and thermal time constants are determined for the Swedish Thermodeck buildings which need essentially no heat in the winter and no chillers in summer. The BECA and other data bases for large buildings are discussed. Off-peak cooling for large buildings is analyzed in terms of saving peak-electrical power. By downsizing chillers and using cheaper, off-peak power, cost-effective thermal storage in new commercial buildings can reduce U.S. peak power demands by 10-20 GW in 15 years. A further potential of about 40 GW is available from adopting partial thermal storage and more efficient air conditioners in existing buildings.

  13. The evolution of the Danube gateway between Central and Eastern Paratethys (SE Europe): Insight from numerical modelling of the causes and effects of connectivity between basins and its expression in the sedimentary record

    NASA Astrophysics Data System (ADS)

    Leever, K. A.; Matenco, L.; Garcia-Castellanos, D.; Cloetingh, S. A. P. L.

    2011-04-01

    The Pannonian and Dacic Basins in SE Europe are presently connected by the Danube River across the South Carpathians, to which they are in a back-arc and foreland position respectively. Part of the Paratethys realm during the Neogene, open water communication between the basins was interrupted by the Late Miocene uplift of the Carpathians. Different mechanisms have been proposed for the formation of the Danube gateway: capture of the upstream lake or an upstream river or incision of an antecedent river. Estimates on its age range from Late Miocene to Quaternary. A related issue is the effect of the large Mediterranean sea level fall related to the Messinian Salinity Crisis on the Paratethys subbasins, specifically the "isolated" Pannonian Basin. In a synthetic numerical modelling study, using a pseudo-3D code integrating tectonics, surface processes and isostasy, we addressed the causes and effects of changes in connectivity between two large sedimentary basins separated by an elevated barrier. Specifically, we aimed to find the expression of connectivity events in the sedimentary record in general and the consequences for the evolution of the Pannonian-Dacic area in particular. We studied a range of parameters including the geometry and uplift rate of the barrier, downstream sea level change and lithosphere rigidity. We found that changes in connectivity are expressed in the sedimentary record through their effect on base level in the upstream basin and supply in the downstream basin. The most important factors controlling the response are the elevation difference between the basins and the upstream accommodation space at the time of reconnection. The most pronounced effect of reconnection through lake capture is predicted for a large elevation difference and limited upstream accommodation space. Downstream increase in sediment supply is dependent on the latter rather than the reconnection event itself. Of the parameters we tested, the rigidity of the lithosphere

  14. An enlightened age: building the naval hospitals.

    PubMed

    Buchanan, Emmakate MacQueen

    2005-01-01

    Summerson writes that, in the spirit of the Enlightenment, the notion of 'bienfaisance', literally meaning the desire to render society more reasonable and more humane, liberated the scope of both hospital and prison planning. Both types of institution housed people who were deprived of their freedom either by disability or by force of law; therefore, we find similarities in the disposition of space and in the degree of humanitarianism expressed in their outward appearance. This observation can be transferred to naval hospital design, where architecture was combined to fulfil a twofold purpose. The high walls, sturdy massing and pared-down details intimated a strict economy of means, but also a strong sense of gravitas and authority. This visual authoritarian character was fundamental to the identity of a naval hospital, for whilst the prime intention was to provide efficient medical care, an equally important consideration was to maintain discipline and prevent sailors from escaping.

  15. Building on Resources in the Information Age

    Technology Transfer Automated Retrieval System (TEKTRAN)

    “We are drowning in data, swept away by information, deluged by publications, and nearly overcome by the challenge of sorting things out in search for a few drops of wisdom”, we read recently. Yet, wisdom, evolving from selective consumption, critical assessment and synthesis of important ideas is s...

  16. Building Buildings with Triangular Numbers

    ERIC Educational Resources Information Center

    Pagni, David L.

    2006-01-01

    Triangular numbers are used to unravel a new sequence of natural numbers here-to-fore not appearing on the Encyclopedia of Integer Sequences website. Insight is provided on the construction of the sequence using "buildings" as a viewable model of the sequence entries. A step-by-step analysis of the sequence pattern reveals a method for generating…

  17. Building Minds by Block Building.

    ERIC Educational Resources Information Center

    Montopoli, Linda

    Noting that the process of playing with blocks supports the groundwork for learning in every area of a child's growth, this paper discusses specific uses of building blocks in the early childhood curriculum to develop a child's physical, social, emotional, artistic, language, scientific and mathematics growth. The paper outlines the contributions…

  18. IMCOM LonWorks (registered trademark) Building Automation Systems Implementation Strategy

    DTIC Science & Technology

    2008-09-01

    of each controller’s configuration pa- rameters 5 High DDC Hardware 1.12.1.b The Building control network backbone shall be a TP- FT10 net- work if a...data sheets and ensure that all installed gateways incorporate one TP/ FT10 network port and one proprietary network port. Review riser diagram and...confirm that proprietary network connection and TP/ FT10 net- work connections exist 12 High DDC Hardware 2.14.1.c All DDC hardware shall incorporate

  19. Confidence building

    NASA Astrophysics Data System (ADS)

    Roederer, Juan G.

    Many conferences are being held on confidence building in many countries. Usually they are organized and attended by political scientists and science policy specialists. A remarkable exception, in which the main brainstorming was done by “grass roots” geophysicists, nuclear physicists, engineers and ecologists, was a meeting in July at St. John's College in Santa Fe, N. Mex.The aim of the conference Technology-Based Confidence Building: Energy and Environment was to survey programs of international cooperation in pertinent areas of mutual concern to all nations and to identify new initiatives that could contribute to enhanced international stability, with emphasis on cooperation between the U.S. and U.S.S.R.

  20. Intelligent buildings.

    PubMed

    Williams, W E

    1987-01-01

    The maturing of technologies in computer capabilities, particularly direct digital signals, has provided an exciting variety of new communication and facility control opportunities. These include telecommunications, energy management systems, security systems, office automation systems, local area networks, and video conferencing. New applications are developing continuously. The so-called "intelligent" or "smart" building concept evolves from the development of this advanced technology in building environments. Automation has had a dramatic effect on facility planning. For decades, communications were limited to the telephone, the typewritten message, and copy machines. The office itself and its functions had been essentially unchanged for decades. Office automation systems began to surface during the energy crisis and, although their newer technology was timely, they were, for the most part, designed separately from other new building systems. For example, most mainframe computer systems were originally stand-alone, as were word processing installations. In the last five years, the advances in distributive systems, networking, and personal computer capabilities have provided opportunities to make such dramatic improvements in productivity that the Selectric typewriter has gone from being the most advanced piece of office equipment to nearly total obsolescence.

  1. Environmental Assessment, Buildings 4133 and Building 4143, Historic Building Demolitions, Barksdale Air Foce Base, Louisiana

    DTIC Science & Technology

    2013-06-01

    following waste being deposited around the building: MOGAS filters, water with fuel, parts washer fluid, paint waste, antifreeze and aerosol cans...Solid and Hazardous Waste/Materials Although no asbestos survey has been conducted on these buildings because of their age, it can be assumed that... Asbestos Containing Material (ACM) occurs within each of them. Removal of the ACM must be conducted according to Occupational Safety and Health

  2. Contrasted climatic trends in the Atlantic vs. Pacific gateways of the Arctic Ocean during the Holocene

    NASA Astrophysics Data System (ADS)

    de Vernal, A.; Hillaire-Marcel, C.; Rochon, A.

    2013-12-01

    The reconstruction of sea-surface conditions including sea ice cover was undertaken based on about 20 marine sediment cores collected in the Arctic Ocean and subarctic seas. The approach has been standardized and mostly relies on the modern analogue technique applied to dinoflagellate cyst assemblages, which permit simultaneous estimates of sea ice cover, summer sea-surface temperature and salinity. The results show some regionalism in both trends, amplitude and overall variability. In general, changes of small amplitude are recorded in the Canadian Arctic whereas a slight cooling trend with an increasing sea ice cover characterizes the Northern Baffin Bay and Fram Strait areas from mid to late Holocene. In contrast, the Chukchi Sea records show large amplitude variations with millennial pacing making difficult to define any trend. The Chukchi Sea data indicate reduced sea ice and warmer conditions during the mid-Holocene, notably around 6.5 and 3.5 ka, and also point to important variations during the last millennium. The overall results suggest a higher variability thus sensitivity to climate change, in the Chukchi Sea area than in the Eastern parts of the Arctic and subarctic regions, which are largely influenced by northern branches of the North Atlantic Drift. The climate sensitivity of the Chukchi Sea area may be related to the proximity of the Pacific gateway. Strong linkages between sea-surface conditions, sea ice cover and export rate seem tightly linked there with large scale atmospheric synopses in the North Pacific and possibly the tropical Pacific. The apparent consistency of the Mount Logan record (Fisher et al., the Holocene 2008) with those of the Chukchi Sea (de Vernal et al., Quat. Sci. Rev. 2013) tends to support the hypothesis of a strong influence of North Pacific atmospheric teleconnections on sea-surface conditions in the Western Arctic.

  3. Windward Passage and Jamaica Channel: New Insights About two Tectonic Gateways of the Northern Caribbean

    NASA Astrophysics Data System (ADS)

    Cormier, M. H.; Blake, R. E.; Coleman, D. F.; Guerrier, K.; Raineault, N.; Saintilus, N.; Walker, S. L.; Auscavitch, S.; Wagner, J.

    2014-12-01

    This August 2014, a 14-day expedition of the E/V NAUTILUS of the OCEAN EXPLORATION TRUST will explore the region delimited by two deep straits of the northern Caribbean, the Windward passage and the Jamaica Channel. The morphology of these straits is controlled by two transform faults: The Septentrional fault, which stretches between Cuba and Haiti (slip rate: ~13 mm/yr), and the Enriquillo-Plantain Garden Fault (EPGF), which stretches between Jamaica and Haiti (slip rate: ~9 mm/yr). Together, these faults bound the Gonave microplate, an elongated platelet caught between the North America plate and Caribbean plates. The Septentrional fault ruptured in 1842, devastating the town of Cap Haitien. The EPGF ruptured catastrophically in 2010 near Port-au-Prince (death toll > 100,000). Tsunamis were associated with both earthquakes. Oblique slip on these two faults is presumably controlling the history of uplift and subsidence of the seafloor, and has therefore also been regulating the water exchanges between the north central Atlantic and the Caribbean Sea. New multibeam bathymetric and CHIRP sub-bottom profiling data will be acquired with the E/V NAUTILUS, while the ROV HERCULES will be used to collect video, water and rock samples, as well as water column physical properties. We anticipate that this survey will document the following: (1) The nature of drowned carbonate platforms, which in turn may provide useful markers to assess rates of vertical deformation along the two faults. (2) The extent of major landslides detected on the steep fore reefs from existing multibeam bathymetric data. (3) Whether fluids are actively seeping along the fault traces or in association with the landslides, as has been reported elsewhere around the World. (4) If cold seeps are indeed present, to what extent their associated ecosystems are affected by the bottom currents that flow through these gateways. Altogether, the new findings should contribute to a better understanding of the

  4. Baker-Barry Tunnel Lighting: Evaluation of a Potential GATEWAY Demonstrations Project

    SciTech Connect

    Tuenge, Jason R.

    2011-06-28

    The U.S. Department of Energy is evaluating the Baker-Barry Tunnel as a potential GATEWAY Demonstrations project for deployment of solid-state lighting (SSL) technology. The National Park Service views this project as a possible proving ground and template for implementation of light-emitting diode (LED) luminaires in other tunnels, thereby expanding the estimated 40% energy savings from 132 MWh/yr to a much larger figure nationally. Most of the energy savings in this application is attributable to the instant-restrike capability of LED products and to their high tolerance for frequent on/off switching, used here to separately control either end of the tunnel during daytime hours. Some LED luminaires rival or outperform their high-intensity discharge (HID) counterparts in terms of efficacy, but options are limited, and smaller lumen packages preclude true one-for-one equivalence. However, LED products continue to improve in efficacy and affordability at a rate unmatched by other light source technologies; the estimated simple payback period of eight years (excluding installation costs and maintenance savings) can be expected to improve with time. The proposed revisions to the existing high-pressure sodium (HPS) lighting system would require slightly increased controls complexity and significantly increased luminaire types and quantities. In exchange, substantial annual savings (from reduced maintenance and energy use) would be complemented by improved quantity and quality of illumination. Although advanced lighting controls could offer additional savings, it is unclear whether such a system would prove cost-effective; this topic may be explored in future work.

  5. Using collaborative two-stage examinations to address test anxiety in a large enrollment gateway course.

    PubMed

    Fournier, Kimberly A; Couret, Jannelle; Ramsay, Jason B; Caulkins, Joshua L

    2017-01-30

    Large enrollment foundational courses are perceived as "high stakes" because of their potential to act as barriers for progression to the next course or admittance to a program. The nature of gateway courses makes them ideal settings to explore the relationship between anxiety, pedagogical interventions, and student performance. Here, two-stage collaborative examinations were implemented to improve test-taking skills and address widespread test anxiety in an introductory human anatomy course. Test anxiety data were collected (using the Motivated Strategies for Learning Questionnaire) before the first examination and last examination. Most students experienced decreased test anxiety over the course of the semester; however, some students may have experienced performance limiting conditions due to test anxiety at the end of the semester based on academic ability in the course (in "C" students when compared to "A" students: P < 0.00006 and "B" students: P < 0.05), overall academic ability (in academically weaker students: P < 0.025), and demographic factors (in women: P < 0.025). The strongest performances on examinations were primarily observed in already academically strong students (mean individual performance: P < 0.000, mean group performance: P < 0.000). Furthermore, changes in test anxiety were not significantly associated with the group portion of the examinations. Patterns of changes in test anxiety over the course of the semester underscore a complex interaction between test anxiety, student background, and student performance. Results suggest that pathways for test anxiety in "high stakes" courses may be separate from the mechanisms responsible for the benefits of collaborative testing. Anat Sci Educ. © 2017 American Association of Anatomists.

  6. FRAM - FRontiers in Arctic marine Monitoring: Permanent Observations in a Gateway to the Arctic Ocean

    NASA Astrophysics Data System (ADS)

    Soltwedel, Thomas

    2015-04-01

    Our ability to understand the complex interactions of biological, chemical, physical, and geological processes in the ocean is still limited by the lack of integrative and interdisciplinary observation infrastructures. The main purpose of the open-ocean infrastructure FRAM (FRontiers in Arctic marine Monitoring) is permanent presence at sea, from surface to depth, for the provision of near real-time data on climate variability and ecosystem change in an Arctic marine environment. The Alfred-Wegener-Institut I Helmholtz-Zentrum für Polar- und Meeresforschung (AWI), together with partner institutes in Germany and Europe, aims at providing such infrastructure for the polar ocean as a major contribution to international efforts towards comprehensive Global Earth Observation. The FRAM Ocean Observing System targets the gateway between the North Atlantic and the Central Arctic, representing a highly climate-sensitive and rapidly changing region of the Earth system. It will serve national and international tasks towards a better understanding of the effects of change in ocean circulation, water mass properties and sea-ice retreat on Arctic marine ecosystems and their main functions and services. FRAM integrates and develops already existing observatories, i.e. the oceanographic mooring array HAFOS (Hybrid Arctic/Antarctic Float Observing System) and the Long-Term Ecological Research (LTER) site HAUSGARTEN. It will implement existing and next-generation sensors and observatory platforms, allowing synchronous observation of relevant ocean variables, as well as the study of physical, chemical and biological processes in the water column and at the seafloor. Experimental and event-triggered platforms will complement observational platforms. Products of the infrastructure are continuous long-term data with appropriate resolution in space and time, as well as ground-truthing information for ocean models and remote sensing.

  7. A gateway cloning vector set for high-throughput functional analysis of genes in planta.

    PubMed

    Curtis, Mark D; Grossniklaus, Ueli

    2003-10-01

    The current challenge, now that two plant genomes have been sequenced, is to assign a function to the increasing number of predicted genes. In Arabidopsis, approximately 55% of genes can be assigned a putative function, however, less than 8% of these have been assigned a function by direct experimental evidence. To identify these functions, many genes will have to undergo comprehensive analyses, which will include the production of chimeric transgenes for constitutive or inducible ectopic expression, for antisense or dominant negative expression, for subcellular localization studies, for promoter analysis, and for gene complementation studies. The production of such transgenes is often hampered by laborious conventional cloning technology that relies on restriction digestion and ligation. With the aim of providing tools for high throughput gene analysis, we have produced a Gateway-compatible Agrobacterium sp. binary vector system that facilitates fast and reliable DNA cloning. This collection of vectors is freely available, for noncommercial purposes, and can be used for the ectopic expression of genes either constitutively or inducibly. The vectors can be used for the expression of protein fusions to the Aequorea victoria green fluorescent protein and to the beta-glucuronidase protein so that the subcellular localization of a protein can be identified. They can also be used to generate promoter-reporter constructs and to facilitate efficient cloning of genomic DNA fragments for complementation experiments. All vectors were derived from pCambia T-DNA cloning vectors, with the exception of a chemically inducible vector, for Agrobacterium sp.-mediated transformation of a wide range of plant species.

  8. A Gateway to Health Careers for Urban High School Students: Collaborative Front-Line and Allied Workforce Development Program among High Schools, Public Hospitals and Public Colleges. Program Results Report

    ERIC Educational Resources Information Center

    Jablow, Paul

    2012-01-01

    From 2005 to 2011, the Gateway Institute for Pre-College Education partnered with three public entities in New York City--the Department of Education, the City University of New York and the Health and Hospitals Corporation--to introduce, educate, and prepare urban high school students for careers in the health professions. Gateway was launched in…

  9. Pleistocene ice-rafted debris events recorded at the Agulhas Plateau - indicators of intermittent Indian-Atlantic gateway closure

    NASA Astrophysics Data System (ADS)

    Ziegler, M.; Hall, I. R.; Siret, P. J.; Zahn, R.

    2012-04-01

    the North Atlantic (McManus et al., 1999, Martrat et al., 2009) after careful synchronization of individual age models using benthic oxygen isotopes. In general, IRD peaks recorded on the Agulhas Plateau occur during globally cold conditions but in anti-phase with coldest events (Heinrich events) in the North Atlantic, which systematically occur at the culmination of large reductions in AMOC. This observation is in line with the concept of a bipolar seesaw behaviour of the glacial Atlantic. As IRD peaks recorded in MD02-2588 tend to precede IRD peaks in the North Atlantic we speculate that the events in the South may have been active in triggering the episodic ice rafting events in the North. A reduced salt export into the Atlantic ocean associated with the southern IRD events may have augmented the destabilization of AMOC activity in the North Atlantic triggering feedbacks in that region, such as basin-wide subsurface warming, increased basal melt rates under an ice shelves fronting the Laurentide Ice Sheet, subsequent collapse allowing ice flow surges and eventually iceberg and freshwater discharge into the Labrador Sea that further amplified weakening of the AMOC (e.g. Alvares-Solas et al., 2010 , Marcott et al., 2011). Ongoing coupled climate and ocean modelling studies will test the feasibility of such a sequence of events. The presented data have been generated within the EU FP7 project "GATEWAYS".

  10. An Efficient Shared Adaptive Packet Loss Concealment Scheme through 1-Port Gateway System for Internet Telephony Service

    NASA Astrophysics Data System (ADS)

    Kim, Jinsul; Lee, Hyunwoo; Ryu, Won; Lee, Byungsun; Hahn, Minsoo

    In this letter, we propose a shared adaptive packet loss concealment scheme for the high quality guaranteed Internet telephony service which connects multiple users. In order to recover packet loss efficiently in the all-IP based convergence environment, we provide a robust signal recovery scheme which is based on the shared adaptive both-side information utilization. This scheme is provided according to the average magnitude variation across the frames and the pitch period replication on the 1-port gateway (G/W) system. The simulated performance demonstrates that the proposed scheme has the advantages of low processing times and high recovery rates in the all-IP based ubiquitous environment.

  11. Molecular dynamics study of Ca(2+) binding loop variants of parvalbumin with modifications at the "gateway" position.

    PubMed

    Elkins, K M; Gatzeva-Topalova, P Z; Nelson, D J

    2001-02-01

    The helix-loop-helix (i.e. EF-hand) Ca(2+) ion binding motif is characteristic of a large family of high-affinity Ca(2+) ion binding proteins, including the parvalbumins and calmodulins. In this paper we describe a set of molecular dynamics computations on the major parvalbumin from the silver hake (SHPV-B). In all variants examined, both whole protein and fragments thereof, the ninth loop residue in the Ca(2+) binding coordination site in the CD helix-loop-helix region (the so-called "gateway" residue) has been mutated. The three gateway mutations examined are arginine, which has never been found at the gateway position of any EF-hand protein, cysteine, which is the residue observed least in natural EF-hand sites, and serine, which is the most common (by far) non-acidic residue substitution at this position in EF-hand proteins in general, but never in parvalbumins. Results of the molecular dynamics simulations indicate that all three modifications are disruptive to the integrity of the mutated Ca(2+) binding site in the whole parvalbumin protein. In contrast, only the arginine and cysteine mutations are disruptive to the integrity of the mutated Ca(2+) binding site in the CD fragment of the parvalbumin protein. Surprisingly, the serine variant of the CD helix-loop-helix fragment exhibited remarkable stability during the entire molecular dynamics simulation, with retention of the Ca(2+) binding site. These results indicate that there are no inherent problems (for Ca(2+) ion binding) associated with the sequence of the CD helix-loop-helix fragment that precludes the incorporation of serine at the gateway position. Since the CD site is totally disrupted in the whole protein serine variant, this indicates that the Ca(2+) ion binding deficiencies are most likely related to the unique interaction that exists between the paired EF-hands in the whole protein. Our theoretical results correlate well with previous studies on engineered EF-hand proteins and with all of our

  12. Understanding nuclear motions in molecules: Derivation of Eckart frame ro-vibrational Hamiltonian operators via a gateway Hamiltonian operator

    SciTech Connect

    Szalay, Viktor

    2015-05-07

    A new ro-vibrational Hamiltonian operator, named gateway Hamiltonian operator, with exact kinetic energy term, T-hat, is presented. It is in the Eckart frame and it is of the same form as Watson’s normal coordinate Hamiltonian. However, the vibrational coordinates employed are not normal coordinates. The new Hamiltonian is shown to provide easy access to Eckart frame ro-vibrational Hamiltonians with exact T-hat given in terms of any desired set of vibrational coordinates. A general expression of the Eckart frame ro-vibrational Hamiltonian operator is given and some of its properties are discussed.

  13. Bindings and RESTlets: A Novel Set of CoAP-Based Application Enablers to Build IoT Applications.

    PubMed

    Teklemariam, Girum Ketema; Van Den Abeele, Floris; Moerman, Ingrid; Demeester, Piet; Hoebeke, Jeroen

    2016-08-02

    Sensors and actuators are becoming important components of Internet of Things (IoT) applications. Today, several approaches exist to facilitate communication of sensors and actuators in IoT applications. Most communications go through often proprietary gateways requiring availability of the gateway for each and every interaction between sensors and actuators. Sometimes, the gateway does some processing of the sensor data before triggering actuators. Other approaches put this processing logic further in the cloud. These approaches introduce significant latencies and increased number of packets. In this paper, we introduce a CoAP-based mechanism for direct binding of sensors and actuators. This flexible binding solution is utilized further to build IoT applications through RESTlets. RESTlets are defined to accept inputs and produce outputs after performing some processing tasks. Sensors and actuators could be associated with RESTlets (which can be hosted on any device) through the flexible binding mechanism we introduced. This approach facilitates decentralized IoT application development by placing all or part of the processing logic in Low power and Lossy Networks (LLNs). We run several tests to compare the performance of our solution with existing solutions and found out that our solution reduces communication delay and number of packets in the LLN.

  14. Bindings and RESTlets: A Novel Set of CoAP-Based Application Enablers to Build IoT Applications

    PubMed Central

    Teklemariam, Girum Ketema; Van Den Abeele, Floris; Moerman, Ingrid; Demeester, Piet; Hoebeke, Jeroen

    2016-01-01

    Sensors and actuators are becoming important components of Internet of Things (IoT) applications. Today, several approaches exist to facilitate communication of sensors and actuators in IoT applications. Most communications go through often proprietary gateways requiring availability of the gateway for each and every interaction between sensors and actuators. Sometimes, the gateway does some processing of the sensor data before triggering actuators. Other approaches put this processing logic further in the cloud. These approaches introduce significant latencies and increased number of packets. In this paper, we introduce a CoAP-based mechanism for direct binding of sensors and actuators. This flexible binding solution is utilized further to build IoT applications through RESTlets. RESTlets are defined to accept inputs and produce outputs after performing some processing tasks. Sensors and actuators could be associated with RESTlets (which can be hosted on any device) through the flexible binding mechanism we introduced. This approach facilitates decentralized IoT application development by placing all or part of the processing logic in Low power and Lossy Networks (LLNs). We run several tests to compare the performance of our solution with existing solutions and found out that our solution reduces communication delay and number of packets in the LLN. PMID:27490554

  15. Bootstrap classification and point-based feature selection from age-staged mouse cerebellum tissues of matrix assisted laser desorption/ionization mass spectra using a fuzzy rule-building expert system.

    PubMed

    Harrington, Peter B; Laurent, Claudine; Levinson, Douglas F; Levitt, Pat; Markey, Sanford P

    2007-09-19

    A bootstrap method for point-based detection of candidate biomarker peaks has been developed from pattern classifiers. Point-based detection methods are advantageous in comparison to peak-based methods. Peak determination and selection are problematic when spectral peaks are not baseline resolved or on a varying baseline. The benefit of point-based detection is that peaks can be globally determined from the characteristic features of the entire data set (i.e., subsets of candidate points) as opposed to the traditional method of selecting peaks from individual spectra and then combining the peak list into a data set. The point-based method is demonstrated to be more effective and efficient using a synthetic data set when compared to using Mahalanobis distance for feature selection. In addition, probabilities that characterize the uniqueness of the peaks are determined. This method was applied for detecting peaks that characterize age-specific patterns of protein expression of developing and adult mouse cerebella from matrix assisted laser desorption/ionization (MALDI) mass spectrometry (MS) data. The mice comprised three age groups: 42 adults, 19 14-day-old pups, and 16 7-day-old pups. Three sequential spectra were obtained from each tissue section to yield 126, 57 and 48 spectra for adult, 14-day-old pup, and 7-day-old pup spectra, respectively. Each spectrum comprised 71,879 mass measurements in a range of 3.5-50 kDa. A previous study revealed that 846 unique peaks were detected that were consistent for 50% of the mice in each age group (C. Laurent, D.F. Levinson, S.A. Schwartz, P.B. Harrington, S.P. Markey, R.M. Caprioli, P. Levitt, Direct profiling of the cerebellum by MALDI MS: a methodological study in postnatal and adult mouse, J. Neurosci. Res. 81 (2005) 613-621.). A fuzzy rule-building expert system (FuRES) was applied to investigate the correlation of age with features in the MS data. FuRES detected two outlier pup-14 spectra. Prediction was evaluated

  16. Gateway Vectors for Simultaneous Detection of Multiple Protein−Protein Interactions in Plant Cells Using Bimolecular Fluorescence Complementation

    PubMed Central

    Hikino, Kazumi; Goto-Yamada, Shino; Nishimura, Mikio; Nakagawa, Tsuyoshi; Mano, Shoji

    2016-01-01

    Bimolecular fluorescence complementation (BiFC) is widely used to detect protein—protein interactions, because it is technically simple, convenient, and can be adapted for use with conventional fluorescence microscopy. We previously constructed enhanced yellow fluorescent protein (EYFP)-based Gateway cloning technology-compatible vectors. In the current study, we generated new Gateway cloning technology-compatible vectors to detect BiFC-based multiple protein—protein interactions using N- and C-terminal fragments of enhanced cyan fluorescent protein (ECFP), enhanced green fluorescent protein (EGFP), and monomeric red fluorescent protein (mRFP1). Using a combination of N- and C-terminal fragments from ECFP, EGFP and EYFP, we observed a shift in the emission wavelength, enabling the simultaneous detection of multiple protein—protein interactions. Moreover, we developed these vectors as binary vectors for use in Agrobacterium infiltration and for the generate transgenic plants. We verified that the binary vectors functioned well in tobacco cells. The results demonstrate that the BiFC vectors facilitate the design of various constructions and are convenient for the detection of multiple protein—protein interactions simultaneously in plant cells. PMID:27490375

  17. The Einstein Genome Gateway using WASP - a high throughput multi-layered life sciences portal for XSEDE.

    PubMed

    Golden, Aaron; McLellan, Andrew S; Dubin, Robert A; Jing, Qiang; O Broin, Pilib; Moskowitz, David; Zhang, Zhengdong; Suzuki, Masako; Hargitai, Joseph; Calder, R Brent; Greally, John M

    2012-01-01

    Massively-parallel sequencing (MPS) technologies and their diverse applications in genomics and epigenomics research have yielded enormous new insights into the physiology and pathophysiology of the human genome. The biggest hurdle remains the magnitude and diversity of the datasets generated, compromising our ability to manage, organize, process and ultimately analyse data. The Wiki-based Automated Sequence Processor (WASP), developed at the Albert Einstein College of Medicine (hereafter Einstein), uniquely manages to tightly couple the sequencing platform, the sequencing assay, sample metadata and the automated workflows deployed on a heterogeneous high performance computing cluster infrastructure that yield sequenced, quality-controlled and 'mapped' sequence data, all within the one operating environment accessible by a web-based GUI interface. WASP at Einstein processes 4-6 TB of data per week and since its production cycle commenced it has processed ~ 1 PB of data overall and has revolutionized user interactivity with these new genomic technologies, who remain blissfully unaware of the data storage, management and most importantly processing services they request. The abstraction of such computational complexity for the user in effect makes WASP an ideal middleware solution, and an appropriate basis for the development of a grid-enabled resource - the Einstein Genome Gateway - as part of the Extreme Science and Engineering Discovery Environment (XSEDE) program. In this paper we discuss the existing WASP system, its proposed middleware role, and its planned interaction with XSEDE to form the Einstein Genome Gateway.

  18. Gateway-compatible vectors for high-throughput gene functional analysis in switchgrass (Panicum virgatum L.) and other monocot species.

    PubMed

    Mann, David G J; Lafayette, Peter R; Abercrombie, Laura L; King, Zachary R; Mazarei, Mitra; Halter, Mathew C; Poovaiah, Charleson R; Baxter, Holly; Shen, Hui; Dixon, Richard A; Parrott, Wayne A; Neal Stewart, C

    2012-02-01

    Switchgrass (Panicum virgatum L.) is a C4 perennial grass and has been identified as a potential bioenergy crop for cellulosic ethanol because of its rapid growth rate, nutrient use efficiency and widespread distribution throughout North America. The improvement of bioenergy feedstocks is needed to make cellulosic ethanol economically feasible, and genetic engineering of switchgrass is a promising approach towards this goal. A crucial component of creating transgenic switchgrass is having the capability of transforming the explants with DNA sequences of interest using vector constructs. However, there are limited options with the monocot plant vectors currently available. With this in mind, a versatile set of Gateway-compatible destination vectors (termed pANIC) was constructed to be used in monocot plants for transgenic crop improvement. The pANIC vectors can be used for transgene overexpression or RNAi-mediated gene suppression. The pANIC vector set includes vectors that can be utilized for particle bombardment or Agrobacterium-mediated transformation. All the vectors contain (i) a Gateway cassette for overexpression or silencing of the target sequence, (ii) a plant selection cassette and (iii) a visual reporter cassette. The pANIC vector set was functionally validated in switchgrass and rice and allows for high-throughput screening of sequences of interest in other monocot species as well.

  19. Resources in the VLab Science Gateway: Online applications for thermodynamics and thermal elastic properties of mantle minerals

    NASA Astrophysics Data System (ADS)

    Wentzcovitch, R. M.; Da Silveira, P. R.; Wu, Z.; Yu, Y.

    2013-12-01

    Today first principles calculations in mineral physics play a fundamental role in understanding of the Earth. They complement experiments by expanding the pressure and temperature range for which properties can be obtained and provide access to atomic scale phenomena. Since the wealth of predictive first principles results can hardly be communicated in printed form, we have developed online applications where published results can be reproduced/verified online and extensive unpublished results can be generated in customized form. So far these applications have included thermodynamics properties of end-member phases and thermal elastic properties of end-member phases and few solid solutions. Extension of this software infrastructure to include other properties is in principle straightforward. This contribution will review the nature of results that can be generated (methods, thermodynamics domain, list of minerals, properties, etc) and nature of the software infrastructure. These applications are part of a more extensive cyber-infrastructure operating in the XSEDE - the VLab Science Gateway [1]. [1] https://www.xsede.org/web/guest/gateways-listing Research supported by NSF grants ATM-0428744 and EAR-1047629.

  20. Analyses of BlueSky Gateway PM2.5 predictions during the 2007 southern and 2008 northern California fires

    NASA Astrophysics Data System (ADS)

    Strand, Tara M.; Larkin, Narasimham; Craig, Kenneth J.; Raffuse, Sean; Sullivan, Dana; Solomon, Robert; Rorig, Miriam; Wheeler, Neil; Pryden, Daniel

    2012-09-01

    We evaluated predictions of hourly PM2.5surface concentrations produced by the experimental BlueSky Gateway air quality modeling system during two wildfire episodes in southern California (Case 1) and northern California (Case 2). In southern California, the prediction performance was dominated by the prevailing synoptic weather patterns, which differentiated the smoke plumes into two types: narrow and highly concentrated during an offshore flow, and diluted and well-mixed during a light onshore flow. For the northern California fires, the prediction performance was dominated by terrain and the limitations of predicting concentrations in a narrow valley, rather than by the synoptic pattern, which did not differ much throughout the wildfire episode. There was an over-prediction bias for the maximum values during this episode. When the predicted values were compared to observed values, the best performance results were for the onshore flow during the southern California fires, indicating that the coarse grid used by BlueSky Gateway appropriately represented these well-mixed conditions. Overall, the southern California fire predictions were biased low and the model did not reproduce the high hourly concentrations (>240μg/m3) observed by the monitors. The predicted results performed well against the observations for the northern California fires, with a large number of predicted values within acceptable range of the observed values.

  1. Polar Gateways Arctic Circle Sunrise 2008 Conference at the Top of the World

    NASA Technical Reports Server (NTRS)

    Cooper, John F.; Kauristie, Kirsti; Weatherwax, Allan T.; Sandahl, Ingrid; Ostgaard, Nikolai; Sheehan, Glenn W.; Smith, Roger W.; Lewis, Elaine M.; Cline, Troy D.; Haines-Stiles, Geoff

    2008-01-01

    The Polar Gateways conference was hosted during January 23-29, 2008, the first week of polar sunrise at Barrow, Alaska, at the new Barrow Arctic Research Center of the Barrow Arctic Science consortium (BASC). The dawn week of polar day, the highly variable low temperatures, and the ice-covered shore tundra and adjacent sea ice conditions provided an appropriate locale for a conference dedicated in the spirit of the International Polar and Heliophysical Years 2007-2009 to the educational exploration of polar and icy world science of Earth and the solar system. The many scientific, educational, and cultural interactions with the local community of four thousand residents, sixty percent native Inupiat Eskimo, further provided an unforgettable experience of what life might be someday be like on other remote polar and icy worlds to be explored and eventually inhabited. Over one hundred active participants, more than half participating remotely, contributed science presentations and educational activities during this unique circumpolar and very "green" conference. Most remote contributions came via videoconference from the Swedish Institute of Space Physics (IRF) at Kisuna, Sweden, the EISCAT Svalbard Radar Facility at Spitzbergen, Norway, the University of Alaska at Fairbanks, NASA Goddard Space Flight Center and the Jet Propulsion Laboratory, the University of California at Berkeley, and the University of Arizona. A few contributors participated via teleconference, including one from the Polar Geophysical Institute at Apatity in Russia. These active contributions spanned up to thirteen time zones (Alaska to Russia) at various tirnes during the conference. Primary videoconferencing support between Barrow and other sites was ably provided by the University of Alaska at Fairbanks, and local operators at each remote site collectively made this conference possible. Science presentations spanned the solar system from the polar Sun and heliospheric environment to Earth, Moon

  2. Impact of the salt leakage through the Indian-Atlantic ocean gateway on the Atlantic MOC

    NASA Astrophysics Data System (ADS)

    Marino, G.; Zahn, R.; Ziveri, P.; Ziegler, M.; Hall, I. R.; Elderfield, H.

    2012-04-01

    Freshwater perturbation in the northern North Atlantic exerts a strong influence on the stability of the Atlantic meridional overturning circulation (AMOC) with potentially severe impacts on the regional and global climates. The occurrence of ice rafted detritus (IRD) in the glacial sediments of the North Atlantic testifies to past episodes of Laurentide ice sheet surging that also coincided with AMOC curtailments and prominent climate deterioration in the Northeast Atlantic and Western Europe. The equally abrupt warming shifts observed in Greenland ice core and North Atlantic sediment core records that characterize the end of each IRD event have been related to the rapid resumption of AMOC and its associated heat transport. The hysteresis response, under glacial boundary conditions, of the AMOC to freshwater forcing suggests that a reduction in this forcing may have been sufficient to trigger the rapid AMOC resumptions revealed by several palaeoceanographic records. But recent modelling studies allude to the potential importance of a salt surplus, originating in the Indian Ocean and transported to the South Atlantic via the Agulhas leakage, that may have acted as a positive feedback on the AMOC strengthening. This possibility, however, has yet to be adequately tested with palaeoproxy reconstructions. We present a suite of multi-centennial-scale palaeoceanographic records spanning a full glacial cycle from the Southwest African margin and Agulhas Plateau that have been generated as part of the EU Marie Curie GATEWAYS project. The sediment cores are positioned such that they monitor the leakage of Agulhas water into the Atlantic and the Agulhas Return Current that straddles the South Atlantic subtropical front on its way to the Indian Ocean. Paired Mg/Ca-δ18O analyses on the planktonic foraminifera Globigerinoides ruber and Globigerina bulloides reveal millennial-scale surface ocean temperature and salinity changes at the core sites that reflect recurrent

  3. Polar Gateways Arctic Circle Sunrise 2008 Conference at the Top of the World

    NASA Astrophysics Data System (ADS)

    Cooper, J. F.; Kauristie, K.; Weatherwax, A. T.; Sheehan, G. W.; Smith, R. W.; Cline, T. D.; Lewis, E. M.; Haines-Stiles, G.

    2008-12-01

    The Polar Gateways conference was hosted during January 23-29, 2008, the first week of polar sunrise at Barrow, Alaska, at the new Barrow Arctic Research Center of the Barrow Arctic Science Consortium (BASC). The dawn week of polar day, the highly variable low temperatures, and the ice-covered shore tundra and adjacent sea ice conditions provided an appropriate locale for a conference dedicated in the spirit of the International Polar and Heliophysical Years 2007-2009 to the educational exploration of polar and icy world science of Earth and the solar system. The many scientific, educational, and cultural interactions with the local community of four thousand residents, sixty percent native Inupiat Eskimo, further provided an unforgettable experience of what life might be someday be like on other remote polar and icy worlds to be explored and eventually inhabited. Over one hundred active participants, more than half participating remotely, contributed science presentations and educational activities during this unique circumpolar and very "green" conference. Most remote contributions came via videoconference from the Swedish Institute of Space Physics (IRF) at Kiruna, Sweden, the EISCAT Svalbard Radar Facility at Spitzbergen, Norway, the University of Alaska at Fairbanks, NASA Goddard Space Flight Center and the Jet Propulsion Laboratory, the University of California at Berkeley, and the University of Arizona. A few contributors participated via teleconference, including one from the Polar Geophysical Institute at Apatity in Russia. These active contributions spanned up to thirteen time zones (Alaska to Russia) at various times during the conference. Primary videoconferencing support between Barrow and other sites was ably provided by the University of Alaska at Fairbanks, and local operators at each remote site collectively made this conference possible. Science presentations spanned the solar system from the polar Sun and heliospheric environment to Earth, Moon

  4. Commercial Buildings Energy Consumption Survey - Office Buildings

    EIA Publications

    2010-01-01

    Provides an in-depth look at this building type as reported in the 2003 Commercial Buildings Energy Consumption Survey. Office buildings are the most common type of commercial building and they consumed more than 17% of all energy in the commercial buildings sector in 2003. This special report provides characteristics and energy consumption data by type of office building (e.g. administrative office, government office, medical office) and information on some of the types of equipment found in office buildings: heating and cooling equipment, computers, servers, printers, and photocopiers.

  5. Molecular dynamics study of Ca(2+) binding loop variants of silver hake parvalbumin with aspartic acid at the "gateway" position.

    PubMed

    Fahie, Kamau; Pitts, Rebecca; Elkins, Kelly; Nelson, Donald J

    2002-04-01

    The helix-loop-helix (i.e., EF-hand) Ca(2+) ion binding motif is characteristic of a large family of high-affinity calcium ion binding proteins, including the parvalbumins, oncomodulins and calmodulins. In this work we describe a set of molecular dynamics computations on the major parvalbumin from the silver hake (SHPV-B) and on functional fragments of this protein, consisting of the first four helical regions (the ABCD fragment), and the internal helix-loop- helix region (the CD fragment). In both whole protein and protein fragments (i.e., ABCD and CD fragments), the 9th loop residue in the calcium ion binding site in the CD helix-loop-helix region (the so-called "gateway" position) has been mutated from glutamic acid to aspartic acid. Aspartic acid is one of the most common residues found at the gateway position in other (non-parvalbumin) EF- hand proteins, but has never been found at the gateway position of any parvalbumin. (Interestingly, aspartic acid does occur at the gateway position in the closely related rat and human oncomodulins.) Consistent with experimental observations, the results of our molecular dynamics simulations show that incorporation of aspartic acid at the gateway position is very disruptive to the structural integrity of the calcium ion coordination site in the whole protein. The aspartic acid mutation is somewhat less disruptive to the calcium ion coordination sites in the two parvalbumin fragments (i.e., the ABCD and CD fragments), presumably due to the higher degree of motional freedom allowable in these protein fragments. One problem associated with the E59D whole protein variant is a prohibitively close approach of the aspartate carboxyl group to the CD calcium ion observed in the energy-minimized (pre-molecular dynamics) structure. This steric situation does not emerge during energy-minimization of the wild-type protein. The damage to the structural integrity of the calcium ion coordination site in the whole protein E59D variant is

  6. Building a Nation of Readers.

    ERIC Educational Resources Information Center

    Library of Congress, Washington, DC. Center for the Book.

    Inviting individuals and families, schools, libraries, educational, civic and government associations, labor unions, and others to join in building a nation of readers, this booklet lists ideas for organizing and supporting reading promotion projects that benefit all age groups. Ideas presented in the booklet include: teach someone to read; set…

  7. Team Building for Youth Sport

    ERIC Educational Resources Information Center

    Bloom, Gordon A.; Loughead, Todd M.; Newin, Julie

    2008-01-01

    Participation in youth sport generally begins to decline after the age of 12. Among the reasons for this are personal aspects such as lack of desire, and social aspects including negative experiences with coaches. One way that coaches can improve the sporting environment is through group activities that promote team building. The purpose of this…

  8. Composition and evolution of the Ancestral South Sandwich Arc: Implications for the flow of deep ocean water and mantle through the Drake Passage Gateway

    NASA Astrophysics Data System (ADS)

    Pearce, J. A.; Hastie, A. R.; Leat, P. T.; Dalziel, I. W.; Lawver, L. A.; Barker, P. F.; Millar, I. L.; Barry, T. L.; Bevins, R. E.

    2014-12-01

    The Ancestral South Sandwich Arc (ASSA) has a short life-span of c. 20 m.y. (early Oligocene to middle-late Miocene) before slab retreat and subsequent 'resurrection' as the active South Sandwich Island Arc (SSIA). The ASSA is, however, significant because it straddled the eastern margin of the Drake Passage Gateway where it formed a potential barrier to deep ocean water and mantle flow from the Pacific to Atlantic. The ASSA may be divided into three parts, from north to south: the Central Scotia Sea (CSS), the Discovery segment, and the Jane segment. Published age data coupled with new geochemical data (major elements, trace elements, Hf-Nd-Sr-Pb isotopes) from the three ASSA segments place constraints on models for the evolution of the arc and hence gateway development. The CSS segment has two known periods of activity. The older, Oligocene, period produced basic-acidic, mostly calc-alkaline rocks, best explained in terms of subduction initiation volcanism of Andean-type (no slab rollback). The younger, middle-late Miocene period produced basic-acidic, high-K calc-alkaline rocks (lavas and pyroclastic rocks with abundant volcanigenic sediments) which, despite being erupted on oceanic crust, have continental arc characteristics best explained in terms of a large, hot subduction flux most typical of a syn- or post-collision arc setting. Early-middle Miocene volcanism in the Discovery and Jane arc segments is geochemically quite different, being typically tholeiitic and compositionally similar to many lavas from the active South Sandwich Island Arc front. There is indirect evidence for Western Pacific-type (slab rollback) subduction initiation in the southern part of the ASSA and for the back-arc basins (the Jane and Scan Basins) to have been active at the time of arc volcanism. Models for the death of the ASSA in the south following a series of ridge-trench collisions are not positively supported by any geochemical evidence of hot subduction, but cessation of

  9. Building energy analysis tool

    DOEpatents

    Brackney, Larry; Parker, Andrew; Long, Nicholas; Metzger, Ian; Dean, Jesse; Lisell, Lars

    2016-04-12

    A building energy analysis system includes a building component library configured to store a plurality of building components, a modeling tool configured to access the building component library and create a building model of a building under analysis using building spatial data and using selected building components of the plurality of building components stored in the building component library, a building analysis engine configured to operate the building model and generate a baseline energy model of the building under analysis and further configured to apply one or more energy conservation measures to the baseline energy model in order to generate one or more corresponding optimized energy models, and a recommendation tool configured to assess the one or more optimized energy models against the baseline energy model and generate recommendations for substitute building components or modifications.

  10. Digital Dilemma: Intellectual Property [and] The ERCIM Technical Reference Digital Library [and] International Information Gateway Collaboration [and] The Standards Fora for Online Education.

    ERIC Educational Resources Information Center

    Gladney, Henry M.; Andreoni, Antonella; Baldacci, Maria Bruna; Biagioni, Stefania; Carlesi, Carlo; Castelli, Donatella; Pagano, Pasquale; Peters, Carol; Pisani, Serena; Dempsey, Lorcan; Gardner, Tracy; Day, Michael; van der Werf, Titia; Bacsich, Paul; Heath, Andy; Lefrere, Paul; Miller, Paul; Riley, Kevin

    1999-01-01

    Includes four articles that discuss the impact of the emerging digital information infrastructure on intellectual property; the implementation of a digital library for a European consortium of national research institutions; an international information gateway collaboration; and developing standards for the description and sharing of educational…

  11. Cigarette Smoking as a Predictor of Alcohol and Other Drug Use by Children and Adolescents: Evidence of the "Gateway Drug Effect."

    ERIC Educational Resources Information Center

    Torabi, Mohammad R.; And Others

    1993-01-01

    Data from a 1992 statewide survey of students in grades 5-12 were analyzed to determine the extent to which cigarette smoking predicted alcohol and other drug use and acted as a gateway drug. Results indicated smoking was a powerful predictor for alcohol and drug use, and the relationship was dose responsive. (SM)

  12. Questioning the Pace and Pathway of E-Government Development in Africa: A Case Study of South Africa's Cape Gateway Project

    ERIC Educational Resources Information Center

    Maumbe, Blessing Mukabeta; Owei, Vesper; Alexander, Helen

    2008-01-01

    The paper examines e-government development in Africa. This study is based on the Cape Gateway project in South Africa, a leading e-government initiative on the continent. We observe that African countries have jumped on the e-government band wagon by looking mostly at the benefits without a clear risk assessment. We argue that African countries…

  13. Preoperational test report, vent building ventilation system

    SciTech Connect

    Clifton, F.T.

    1997-11-04

    This represents a preoperational test report for Vent Building Ventilation Systems, Project W-030. Project W-030 provides a ventilation upgrade for the four Aging Waste Facility tanks. The system provides Heating, Ventilation, and Air Conditioning (HVAC) for the W-030 Ventilation Building. The tests verify correct system operation and correct indications displayed by the central Monitor and Control System.

  14. Building America

    SciTech Connect

    Brad Oberg

    2010-12-31

    Builders generally use a 'spec and purchase' business management system (BMS) when implementing energy efficiency. A BMS is the overall operational and organizational systems and strategies that a builder uses to set up and run its company. This type of BMS treats building performance as a simple technology swap (e.g. a tank water heater to a tankless water heater) and typically compartmentalizes energy efficiency within one or two groups in the organization (e.g. purchasing and construction). While certain tools, such as details, checklists, and scopes of work, can assist builders in managing the quality of the construction of higher performance homes, they do nothing to address the underlying operational strategies and issues related to change management that builders face when they make high performance homes a core part of their mission. To achieve the systems integration necessary for attaining 40% + levels of energy efficiency, while capturing the cost tradeoffs, builders must use a 'systems approach' BMS, rather than a 'spec and purchase' BMS. The following attributes are inherent in a systems approach BMS; they are also generally seen in quality management systems (QMS), such as the National Housing Quality Certification program: Cultural and corporate alignment, Clear intent for quality and performance, Increased collaboration across internal and external teams, Better communication practices and systems, Disciplined approach to quality control, Measurement and verification of performance, Continuous feedback and improvement, and Whole house integrated design and specification.

  15. 3. Historic American Buildings Survey Lanny Miyamoto, Photographer October 1958 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey Lanny Miyamoto, Photographer October 1958 FOYER, WITH STAIRCASE AND DOORWAY TO SALON - Aged Men's Home, 1400 West Lexington Street, Baltimore, Independent City, MD

  16. 5. Historic American Buildings Survey Lanny Miyamoto, Photographer October 1958 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Historic American Buildings Survey Lanny Miyamoto, Photographer October 1958 SAMPLE ROOM, LOOKING FROM SALON, FIRST FLOOR - Aged Women's Home, 1400 West Lexington Street, Baltimore, Independent City, MD

  17. Virtual Labs (Science Gateways) as platforms for Free and Open Source Science

    NASA Astrophysics Data System (ADS)

    Lescinsky, David; Car, Nicholas; Fraser, Ryan; Friedrich, Carsten; Kemp, Carina; Squire, Geoffrey

    2016-04-01

    The Free and Open Source Software (FOSS) movement promotes community engagement in software development, as well as provides access to a range of sophisticated technologies that would be prohibitively expensive if obtained commercially. However, as geoinformatics and eResearch tools and services become more dispersed, it becomes more complicated to identify and interface between the many required components. Virtual Laboratories (VLs, also known as Science Gateways) simplify the management and coordination of these components by providing a platform linking many, if not all, of the steps in particular scientific processes. These enable scientists to focus on their science, rather than the underlying supporting technologies. We describe a modular, open source, VL infrastructure that can be reconfigured to create VLs for a wide range of disciplines. Development of this infrastructure has been led by CSIRO in collaboration with Geoscience Australia and the National Computational Infrastructure (NCI) with support from the National eResearch Collaboration Tools and Resources (NeCTAR) and the Australian National Data Service (ANDS). Initially, the infrastructure was developed to support the Virtual Geophysical Laboratory (VGL), and has subsequently been repurposed to create the Virtual Hazards Impact and Risk Laboratory (VHIRL) and the reconfigured Australian National Virtual Geophysics Laboratory (ANVGL). During each step of development, new capabilities and services have been added and/or enhanced. We plan on continuing to follow this model using a shared, community code base. The VL platform facilitates transparent and reproducible science by providing access to both the data and methodologies used during scientific investigations. This is further enhanced by the ability to set up and run investigations using computational resources accessed through the VL. Data is accessed using registries pointing to catalogues within public data repositories (notably including the

  18. Opening a Gateway to College Access: Algebra at the Right Time. Research Brief

    ERIC Educational Resources Information Center

    Snipes, Jason; Finkelstein, Neal

    2015-01-01

    Four years of math in high school, with a strong foundation in algebra that builds from middle school, is key to higher education access. Therefore, ensuring that middle and high school students succeed in math--and in algebra in particular--is an important issue for policy and practice. This research brief examines three recent Regional…

  19. A Gateway to Integration: A Study of American Families and Their International Visitors

    ERIC Educational Resources Information Center

    Hellmann, Kate; Miyazaki, Rachel; Miranda, Daniela; Fiscus, Tricia

    2016-01-01

    Research shows that helping international students build support networks by forming new friendships is crucial to counteracting the feelings of isolation, loneliness, and frustration that may arise from studying abroad. Studies have shown that friendships between international students and host nationals benefit the local community rather than…

  20. Academic Libraries as High-Tech Gateways: A Guide to Design & Space Decisions. Second Edition.

    ERIC Educational Resources Information Center

    Bazillion, Richard J.; Braun, Connie L.

    This book, based on research about libraries around the country, provides tools that can be used for planning and building an academic library space that streamlines access to information. It explains how to incorporate the latest innovations in academic library facility design; how to make the facility flexible for changing information technology…

  1. A Distributed Intelligent Automated Demand Response Building Management System

    SciTech Connect

    Auslander, David; Culler, David; Wright, Paul; Lu, Yan; Piette, Mary

    2013-03-31

    The goal of the 2.5 year Distributed Intelligent Automated Demand Response (DIADR) project was to reduce peak electricity load of Sutardja Dai Hall at UC Berkeley by 30% while maintaining a healthy, comfortable, and productive environment for the occupants. We sought to bring together both central and distributed control to provide “deep” demand response1 at the appliance level of the building as well as typical lighting and HVAC applications. This project brought together Siemens Corporate Research and Siemens Building Technology (the building has a Siemens Apogee Building Automation System (BAS)), Lawrence Berkeley National Laboratory (leveraging their Open Automated Demand Response (openADR), Auto-­Demand Response, and building modeling expertise), and UC Berkeley (related demand response research including distributed wireless control, and grid-­to-­building gateway development). Sutardja Dai Hall houses the Center for Information Technology Research in the Interest of Society (CITRIS), which fosters collaboration among industry and faculty and students of four UC campuses (Berkeley, Davis, Merced, and Santa Cruz). The 141,000 square foot building, occupied in 2009, includes typical office spaces and a nanofabrication laboratory. Heating is provided by a district heating system (steam from campus as a byproduct of the campus cogeneration plant); cooling is provided by one of two chillers: a more typical electric centrifugal compressor chiller designed for the cool months (Nov-­ March) and a steam absorption chiller for use in the warm months (April-­October). Lighting in the open office areas is provided by direct-­indirect luminaries with Building Management System-­based scheduling for open areas, and occupancy sensors for private office areas. For the purposes of this project, we focused on the office portion of the building. Annual energy consumption is approximately 8053 MWh; the office portion is estimated as 1924 MWh. The maximum peak load

  2. Building the Next Generation of Scientists with US-Africa Exchange Programs

    NASA Astrophysics Data System (ADS)

    Sheth, Kartik

    2014-01-01

    In the past couple of decades and in the upcoming decade an explosion of cutting edge multi-wavelength facilities have begun or are expected to be operating across the African continent (SALT, HESS, MITRA, AVN, PAPER, MeerKAT, African VLBI and the SKA). At the same time countries across the continent are developing human capacity in science and technology using astronomy as a gateway science. Building on previous collaborations between the National Radio Astronomy Observatory and South Africa, we are embarking on an effort to build a new international (and national) partnership to exchange students and faculty between the US and the African continent. I will describe the status and future development plans for this program.

  3. Internet-to-orbit gateway and virtual ground station: A tool for space research and scientific outreach

    NASA Astrophysics Data System (ADS)

    Jaffer, Ghulam; Nader, Ronnie; Koudelka, Otto

    2011-09-01

    Students in higher education, and scientific and technological researchers want to communicate with the International Space Station (ISS), download live satellite images, and receive telemetry, housekeeping and science/engineering data from nano-satellites and larger spacecrafts. To meet this need the Ecuadorian Civilian Space Agency (EXA) has recently provided the civilian world with an internet-to-orbit gateway (Hermes-A/Minotaur) Space Flight Control Center (SFCC) available for public use. The gateway has a maximum range of tracking and detection of 22,000 km and sensitivity such that it can receive and discriminate the signals from a satellite transmitter with power˜0.1 W. The capability is enough to receive the faintest low-earth-orbit (LEO) satellites. This gateway virtually connects participating internet clients around the world to a remote satellite ground station (GS), providing a broad community for multinational cooperation. The goal of the GS is to lower financial and engineering barriers that hinder access to science and engineering data from orbit. The basic design of the virtual GS on a user side is based on free software suites. Using these and other software tools the GS is able to provide access to orbit for a multitude of users without each having to go through the costly setups. We present the design and implementation of the virtual GS in a higher education and scientific outreach settings. We also discuss the basic architecture of the single existing system and the benefits of a proposed distributed system. Details of the software tools and their applicability to synchronous round-the-world tracking, monitoring and processing performed by students and teams at Graz University of Technology, Austria, EXA-Ecuador, University of Michigan, USA and JAXA who have participated in various mission operations and have investigated real-time satellite data download and image acquisition and processing. Students and other remote users at these

  4. Modified single transluminal gateway transcystic multiple drainage technique for a huge infected walled-off pancreatic necrosis: A case report

    PubMed Central

    Minaga, Kosuke; Kitano, Masayuki; Imai, Hajime; Yamao, Kentaro; Kamata, Ken; Miyata, Takeshi; Matsuda, Tomohiko; Omoto, Shunsuke; Kadosaka, Kumpei; Yoshikawa, Tomoe; Kudo, Masatoshi

    2016-01-01

    We report a successful endoscopic ultrasonography-guided drainage of a huge infected multilocular walled-off necrosis (WON) that was treated by a modified single transluminal gateway transcystic multiple drainage (SGTMD) technique. After placing a wide-caliber fully covered metal stent, follow-up computed tomography revealed an undrained subcavity of WON. A large fistula that was created by the wide-caliber metal stent enabled the insertion of a forward-viewing upper endoscope directly into the main cavity, and the narrow connection route within the main cavity to the subcavity was identified with a direct view, leading to the successful drainage of the subcavity. This modified SGTMD technique appears to be useful for seeking connection routes between subcavities of WON in some cases. PMID:27275106

  5. Internet Technology in Magnetic Resonance: A Common Gateway Interface Program for the World-Wide Web NMR Spectrometer

    NASA Astrophysics Data System (ADS)

    Buszko, Marian L.; Buszko, Dominik; Wang, Daniel C.

    1998-04-01

    A custom-written Common Gateway Interface (CGI) program for remote control of an NMR spectrometer using a World Wide Web browser has been described. The program, running on a UNIX workstation, uses multiple processes to handle concurrent tasks of interacting with the user and with the spectrometer. The program's parent process communicates with the browser and sends out commands to the spectrometer; the child process is mainly responsible for data acquisition. Communication between the processes is via the shared memory mechanism. The WWW pages that have been developed for the system make use of the frames feature of web browsers. The CGI program provides an intuitive user interface to the NMR spectrometer, making, in effect, a complex system an easy-to-use Web appliance.

  6. Magmatism in western Indonesia, the trapping of the Sumba Block and the gateways to the east of Sundaland

    NASA Astrophysics Data System (ADS)

    Soeria-Atmadja, R.; Suparka, S.; Abdullah, Chalid; Noeradi, Dardji; Sutanto

    1998-04-01

    The western Sulawesi magmatic belt and the Sunda-Banda arc define the eastern and south-eastern margins of Sundaland, which is part of the relatively stable Eurasian plate. The eastern margin is bounded by the Makassar Strait which separates western Sulawesi from Kalimantan. The initial opening of the Makassar Strait took place in the late Cretaceous-Early Tertiary leading to the opening of the Pacific-Indian Ocean gateway during Neogene time. Recent studies indicate similarities in the late Cretaceous-Paleogene stratigraphic sequence and calc-alkali magmatism between Sumba, south Sulawesi and south-east Kalimantan, suggesting a Sundaland origin for all of these areas. The southward migration of Sumba to the present frontal arc position of the Sunda-Banda arc has occurred since Late Cretaceous-Paleocene time.

  7. Gateway-assisted vector construction to facilitate expression of foreign proteins in the chloroplast of single celled algae.

    PubMed

    Oey, Melanie; Ross, Ian L; Hankamer, Ben

    2014-01-01

    With a rising world population, demand will increase for food, energy and high value products. Renewable production systems, including photosynthetic microalgal biotechnologies, can produce biomass for foods, fuels and chemical feedstocks and in parallel allow the production of high value protein products, including recombinant proteins. Such high value recombinant proteins offer important economic benefits during startup of industrial scale algal biomass and biofuel production systems, but the limited markets for individual recombinant proteins will require a high throughput pipeline for cloning and expression in microalgae, which is currently lacking, since genetic engineering of microalgae is currently complex and laborious. We have introduced the recombination based Gateway® system into the construction process of chloroplast transformation vectors for microalgae. This simplifies the vector construction and allows easy, fast and flexible vector design for the high efficiency protein production in microalgae, a key step in developing such expression pipelines.

  8. Building 1100--NASA

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Building 1100 is the NASA administrative building. Services located in this building include two banks, a post office, barber shop, cafeteria, snack bar, travel agency, dry cleaners, the NASA Exchange retail store and medical facilities for employees.

  9. BUILDING 341 Seismic Evaluation

    SciTech Connect

    Halle, J.

    2015-06-15

    The Seismic Evaluation of Building 341 located at Lawrence Livermore National Laboratory in Livermore, California has been completed. The subject building consists of a main building, Increment 1, and two smaller additions; Increments 2 and 3.

  10. Tribal Green Building Toolkit

    EPA Pesticide Factsheets

    This Tribal Green Building Toolkit (Toolkit) is designed to help tribal officials, community members, planners, developers, and architects develop and adopt building codes to support green building practices. Anyone can use this toolkit!

  11. The Wind ENergy Data and Information (WENDI) Gateway: New Information and Analysis Tools for Wind Energy Stakeholders

    NASA Astrophysics Data System (ADS)

    Kaiser, D.; Palanisamy, G.; Santhana Vannan, S.; Wei, Y.; Smith, T.; Starke, M.; Wibking, M.; Pan, Y.; Devarakonda, Ranjeet; Wilson, B. E.; Wind Energy Data; Information (WENDI) Gateway Team

    2010-12-01

    In support of the U.S. Department of Energy’s (DOE) Energy Efficiency and Renewable Energy (EERE) Office, DOE's Oak Ridge National Laboratory (ORNL) has launched the Wind ENergy Data & Information (WENDI) Gateway. The WENDI Gateway is intended to serve a broad range of wind-energy stakeholders by providing easy access to a large amount of wind energy-related data and information through its two main interfaces: the Wind Energy Metadata Clearinghouse and the Wind Energy Geographic Information System (WindGIS). The Metadata Clearinghouse is a powerful, customized search tool for discovering, accessing, and sharing wind energy-related data and information. Its database of metadata records points users to a diverse array of wind energy-related resources: from technical and scientific journal articles to mass media news stories; from annual government and industry reports to downloadable datasets, and much more. Through the WindGIS, users can simultaneously visualize a wide spectrum of United States wind energy-related spatial data, including wind energy power plant locations; wind resource maps; state-level installed wind capacity, generation, and renewable portfolio standards; electric transmission lines; transportation infrastructure; interconnection standards; land ownership, designation, and usage; and various ecological data layers. In addition, WindGIS allows users to download much of the data behind the layers. References: [1] Devarakonda R., et al. Mercury: reusable metadata management, data discovery and access system. Earth Science Informatics (2010), 3(1): 87-94. [2] Wilson, Bruce E., et al. "Mercury Toolset for Spatiotemporal Metadata." (2010).

  12. 9. Building 105, Facilities Engineering Building, 1830, interior, Tin Metal ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Building 105, Facilities Engineering Building, 1830, interior, Tin Metal area of building, looking S. - Watervliet Arsenal, Building 105, South Broadway, on Hudson River, Watervliet, Albany County, NY

  13. Gestational age

    MedlinePlus

    Fetal age - gestational age; Gestation; Neonatal gestational age; Newborn gestational age ... Gestational age can be determined before or after birth. Before birth, your health care provider will use ultrasound to ...

  14. Aging Skin

    MedlinePlus

    ... email address Submit Home > Healthy Aging > Wellness Healthy Aging Aging skin More information on aging skin When it ... treated early. Return to top More information on Aging skin Read more from womenshealth.gov Varicose Veins ...

  15. [Nutrition, aging, old age].

    PubMed

    Iván, L

    1998-12-06

    In humans there is evidence that the restriction of total caloric intake appears to be more important than the restriction of any particular macronutrient. Today the mechanism of the effect of caloric restriction is unknown. With advancing age and the occurrence of concomitant illness there is an increased risk of developing nutritional deficiencies. Altered nutritional status is associated with the pathogenesis of a number of common diseases of the elderly, thus it would appear that nutritional modulation and manipulation represents one possible approach to successful aging and a healthy longevity. The conceptual framework of the paper suggests the need of a newer light of the aging processes namely by a holistic human-gero-ecological model and a personality oriented geriatry. There are accentuated the role of the nutrients and vitamins, the food intake and drug-nutrients interactions and the meanings of the differences between the normal and pathological aging.

  16. A Good Age.

    ERIC Educational Resources Information Center

    Smith, Bert Kruger

    The story of the Austin Groups for the Elderly (AGE), a conglomeration of service agencies serving older adults and children, is related in this document. The agencies' decision to coordinate services as much as possible and to share a building to facilitate coordination and lower costs in financially difficult times is explained. The activities…

  17. Early Learning Left Out: Building an Early-Learning System to Secure America's Future. Federal, State and School District Investments by Child Age. 4th Edition. 2010-2012

    ERIC Educational Resources Information Center

    Bruner, Charles

    2013-01-01

    As a society, are we investing enough in our youngest children? The BUILD Initiative's latest report, Early Learning Left Out, by CFPC director Charles Bruner, provides a clear answer that current investments fall far short. The report draws upon the most recent federal, state, and public school budget information--and what we know about effective…

  18. Modular Buildings Buying Guide.

    ERIC Educational Resources Information Center

    Morris, Susan

    1991-01-01

    Suggests that child care program directors who are expanding their programs or opening new child care centers investigate the possibility of renting, leasing, or purchasing a modular building. Discusses the advantages of modular buildings over conventional building construction or rented space in an occupied building. Provides information about…

  19. The Building Commissioning Handbook.

    ERIC Educational Resources Information Center

    Heinz, John A.; Casault, Rick

    This book discusses building commissioning, which is the process of certifying that a new facility meets the required specifications. As buildings have become more complex, the traditional methods for building start-up and final acceptance have been proven inadequate, and building commissioning has been developed, which often necessitates the use…

  20. [From the deposit to the reception accommodation for immigrants: the genesis of an "inspection gateway center" on the path to emigration to Brazil].

    PubMed

    Chrysostomo, Maria Isabel de Jesus; Vidal, Laurent

    2014-01-01

    The scope of this paper is to reflect upon the emergence and organization of territorial and administrative arrangements, qualified here as inspection gateway centers, for the control and screening of migrants at the moment of entry into Brazil. Between the reuse of existing forms (deposits, warehouses) in the first half of the nineteenth century and the invention of a new form (the inspection gateway center), in the late nineteenth century, long debates mobilizing various actors (in the political, economic, and medical world) revolved around various questions. What is the most appropriate spatial and architectural form for temporary shelter? How to enhance the waiting time to carry out administrative and health controls, making it possible to define the desirable immigrant?

  1. Enabling prominent high-rate and cycle performances in one lithium-sulfur battery: designing permselective gateways for Li(+) transportation in Holey-CNT/S cathodes.

    PubMed

    Zhou, Yin; Zhou, Chenggang; Li, Qiyang; Yan, Chunjie; Han, Bo; Xia, Kaisheng; Gao, Qiang; Wu, Jinping

    2015-07-01

    A cathode material composed of h-CNT/S/ZrO2 is developed for lithium-sulfur batteries. By incorporating ZrO2 into the S-incorporated h-CNT, permselective gateways for free Li(+) transportation can be assembled at the mesopore openings, which deny the penetration of lithium polysulfides. At the ultrahigh rate of 10 C, the discharge capacity averages to be 870 mA h g(-1) within 200 cycles.

  2. WebSpace - a WebWindows based gateway to the ANL LabSpace. Final report for period September 1, 1995 - August 31, 1998

    SciTech Connect

    Furmanski, Wojtek

    2002-04-11

    The goal of this project was to prototype a Web based computational and collaboratory environment that would act as a commodity technologies based front-end or Gateway to larger HPC systems such as ANL LabSpace. The original name - WebSpace - proposed for such a system was taken during the course of this project by Silicon Graphics and used for their Web authoring environment. To avoid confusion, we changed the name of this project's system to WebFlow.

  3. Comparing the impacts of Miocene-Pliocene changes in inter-ocean gateways on climate: Central American Seaway, Bering Strait, and Indonesia

    NASA Astrophysics Data System (ADS)

    Brierley, Chris M.; Fedorov, Alexey V.

    2016-06-01

    Changes in inter-ocean gateways caused by tectonic processes have been long considered an important factor in climate evolution on geological timescales. Three major gateway changes that occurred during the Late Miocene and Pliocene epochs are the closing of the Central American Seaway (CAS) by the uplift of the Isthmus of Panama, the opening of the Bering Strait, and the closing of a deep channel between New Guinea and the Equator. This study compares the global climatic effects of these changes within the same climate model framework. We find that the closure of the CAS and the opening of the Bering Strait induce the strongest effects on the Atlantic meridional overturning circulation (AMOC). However, these effects potentially compensate, as the closure of the CAS and the opening of the Bering Strait cause similar AMOC changes of around 2 Sv (strengthening and weakening respectively). Previous simulations with an open CAS consistently simulated colder oceanic conditions in the Northern Hemisphere - contrasting with the evidence for warmer sea surface temperatures 10-3 million years ago. Here we argue that this cooling is overestimated because (a) the models typically simulated too strong an AMOC change not yet in equilibrium, (b) used a channel too deep and (c) lacked the compensating effect of the closed Bering Strait - a factor frequently ignored despite its potential influence on northern high latitudes and ice-sheet growth. Further, we discuss how these gateway changes affect various climatic variables from surface temperature and precipitation to ENSO characteristics.

  4. In-Frame and Unmarked Gene Deletions in Burkholderia cenocepacia via an Allelic Exchange System Compatible with Gateway Technology.

    PubMed

    Fazli, Mustafa; Harrison, Joe J; Gambino, Michela; Givskov, Michael; Tolker-Nielsen, Tim

    2015-06-01

    Burkholderia cenocepacia is an emerging opportunistic pathogen causing life-threatening infections in immunocompromised individuals and in patients with cystic fibrosis, which are often difficult, if not impossible, to treat. Understanding the genetic basis of virulence in this emerging pathogen is important for the development of novel treatment regimes. Generation of deletion mutations in genes predicted to encode virulence determinants is fundamental to investigating the mechanisms of pathogenesis. However, there is a lack of appropriate selectable and counterselectable markers for use in B. cenocepacia, making its genetic manipulation problematic. Here we describe a Gateway-compatible allelic exchange system based on the counterselectable pheS gene and the I-SceI homing endonuclease. This system provides efficiency in cloning homology regions of target genes and allows the generation of precise and unmarked gene deletions in B. cenocepacia. As a proof of concept, we demonstrate its utility by deleting the Bcam1349 gene, encoding a cyclic di-GMP (c-di-GMP)-responsive regulator protein important for biofilm formation.

  5. In-Frame and Unmarked Gene Deletions in Burkholderia cenocepacia via an Allelic Exchange System Compatible with Gateway Technology

    PubMed Central

    Fazli, Mustafa; Harrison, Joe J.; Gambino, Michela; Givskov, Michael

    2015-01-01

    Burkholderia cenocepacia is an emerging opportunistic pathogen causing life-threatening infections in immunocompromised individuals and in patients with cystic fibrosis, which are often difficult, if not impossible, to treat. Understanding the genetic basis of virulence in this emerging pathogen is important for the development of novel treatment regimes. Generation of deletion mutations in genes predicted to encode virulence determinants is fundamental to investigating the mechanisms of pathogenesis. However, there is a lack of appropriate selectable and counterselectable markers for use in B. cenocepacia, making its genetic manipulation problematic. Here we describe a Gateway-compatible allelic exchange system based on the counterselectable pheS gene and the I-SceI homing endonuclease. This system provides efficiency in cloning homology regions of target genes and allows the generation of precise and unmarked gene deletions in B. cenocepacia. As a proof of concept, we demonstrate its utility by deleting the Bcam1349 gene, encoding a cyclic di-GMP (c-di-GMP)-responsive regulator protein important for biofilm formation. PMID:25795676

  6. The role of ocean gateways in the dynamics and sensitivity to wind stress of the early Antarctic Circumpolar Current

    NASA Astrophysics Data System (ADS)

    Munday, D. R.; Johnson, H. L.; Marshall, D. P.

    2015-03-01

    The date of inception of the Antarctic Circumpolar Current is debated due to uncertainty in the relative opening times of Drake Passage and the Tasman Seaway. Using an idealized eddy-resolving numerical ocean model, we investigate whether both ocean gateways have to be open to allow for a substantial circumpolar current. We find that overlapping continental barriers do not impede a circumpolar transport in excess of 50Sv, as long as a circumpolar path can be traced around the barriers. However, the presence of overlapping barriers does lead to an increased sensitivity of the current's volume transport to changes in wind stress. This change in sensitivity is interpreted in terms of the role of pressure drops across continental barriers and submerged bathymetry in balancing the momentum input by the surface wind stress. Specifically, when the pressure drop across continents is the main balancing sink of momentum, the zonal volume transport is sensitive to changes in wind stress. Changes in zonal volume transport take place via altering the depth-independent part of the circumpolar transport rather than that arising from thermal wind shear. In such a scenario, isopycnals continue to slope steeply across the model Southern Ocean, implying a strong connection between the deep and surface oceans. This may have consequences for the meridional overturning circulation and its sensitivity to wind stress.

  7. The Jaramillo Bottleneck for Migration of Hominins with Megaherbivores Into Europe via the Danube-Po Gateway

    NASA Astrophysics Data System (ADS)

    Muttoni, G.; Kent, D. V.; Scardia, G.

    2015-12-01

    Based on ongoing magnetostratigraphic work and updated critical reviews of sites bearing hominin remains and/or tools from greater Europe, including the Balkans and Greece, we maintain that the only compelling evidence of hominin presence in these regions was after the Jaramillo subchron (0.99 Ma), at about the time of the climatic late Early Pleistocene revolution (EPR) and the onset of enhanced glacial/interglacial activity from MIS 22 onward. Europe may have become initially populated during the EPR when, possibly for the first time in the Pleistocene, vast and exploitable ecosystems were generated along the Danube-Po Gateway in the Balkan peninsula and northern Italy. These newly formed settings, characterized by low-lands with open grasslands and reduced woody cover during glacial/interglacial transitions, represented the closest analogues to the savanna environment to which several large mammals linked with hominins in a common food web were adapted and could use as a migratory corridor. We acknowledge that lack of evidence may not be a compelling argument, but the absence of the Jaramillo and out-of-sequence cosmogenic nuclide dates with wide error margins in key sections preclude the use of such evidence to substantiate the presence of humans (and presumably associated biostratigraphic markers) prior to the Jaramillo, and thus logically deny applying such conclusions to other systems.

  8. Production of mouse granulocyte-macrophage colony-stimulating factor by gateway technology and transgenic rice cell culture.

    PubMed

    Liu, Yu-Kuo; Huang, Li-Fen; Ho, Shin-Lon; Liao, Chun-Yu; Liu, Hsin-Yi; Lai, Ying-Hui; Yu, Su-May; Lu, Chung-An

    2012-05-01

    To establish a production platform for recombinant proteins in rice suspension cells, we first constructed a Gateway-compatible binary T-DNA destination vector. It provided a reliable and effective method for the rapid directional cloning of target genes into plant cells through Agrobacterium-mediated transformation. We used the approach to produce mouse granulocyte-macrophage colony-stimulating factor (mGM-CSF) in a rice suspension cell system. The promoter for the αAmy3 amylase gene, which is induced strongly by sugar depletion, drove the expression of mGM-CSF. The resulting recombinant protein was fused with the αAmy3 signal peptide and was secreted into the culture medium. The production of rice-derived mGM-CSF (rmGM-CSF) was scaled up successfully in a 2-L bioreactor, in which the highest yield of rmGM-CSF was 24.6 mg/L. Due to post-translational glycosylation, the molecular weight of rmGM-CSF was larger than that of recombinant mGM-CSF produced in Escherichia coli. The rmGM-CSF was bioactive and could stimulate the proliferation of a murine myeloblastic leukemia cell line, NSF-60.

  9. D1/D5 receptors and histone deacetylation mediate the Gateway Effect of LTP in hippocampal dentate gyrus.

    PubMed

    Huang, Yan-You; Levine, Amir; Kandel, Denise B; Yin, Deqi; Colnaghi, Luca; Drisaldi, Bettina; Kandel, Eric R

    2014-02-18

    The dentate gyrus (DG) of the hippocampus is critical for spatial memory and is also thought to be involved in the formation of drug-related associative memory. Here, we attempt to test an aspect of the Gateway Hypothesis, by studying the effect of consecutive exposure to nicotine and cocaine on long-term synaptic potentiation (LTP) in the DG. We find that a single injection of cocaine does not alter LTP. However, pretreatment with nicotine followed by a single injection of cocaine causes a substantial enhancement of LTP. This priming effect of nicotine is unidirectional: There is no enhancement of LTP if cocaine is administrated prior to nicotine. The facilitation induced by nicotine and cocaine can be blocked by oral administration of the dopamine D1/D5 receptor antagonist (SKF 83566) and enhanced by the D1/D5 agonist (SKF 38393). Application of the histone deacetylation inhibitor suberoylanilide hydroxamic acid (SAHA) simulates the priming effect of nicotine on cocaine. By contrast, the priming effect of nicotine on cocaine is blocked in genetically modified mice that are haploinsufficient for the CREB-binding protein (CBP) and possess only one functional CBP allele and therefore exhibit a reduction in histone acetylation. These results demonstrate that the DG of the hippocampus is an important brain region contributing to the priming effect of nicotine on cocaine. Moreover, both activation of dopamine-D1 receptor/PKA signaling pathway and histone deacetylation/CBP mediated transcription are required for the nicotine priming effect in the DG.

  10. MultiSite Gateway-Compatible Cell Type-Specific Gene-Inducible System for Plants1[OPEN

    PubMed Central

    Siligato, Riccardo; Wang, Xin; Yadav, Shri Ram; Lehesranta, Satu; Ma, Guojie; Ursache, Robertas; Sevilem, Iris; Zhang, Jing; Gorte, Maartje; Prasad, Kalika; Heidstra, Renze

    2016-01-01

    A powerful method to study gene function is expression or overexpression in an inducible, cell type-specific system followed by observation of consequent phenotypic changes and visualization of linked reporters in the target tissue. Multiple inducible gene overexpression systems have been developed for plants, but very few of these combine plant selection markers, control of expression domains, access to multiple promoters and protein fusion reporters, chemical induction, and high-throughput cloning capabilities. Here, we introduce a MultiSite Gateway-compatible inducible system for Arabidopsis (Arabidopsis thaliana) plants that provides the capability to generate such constructs in a single cloning step. The system is based on the tightly controlled, estrogen-inducible XVE system. We demonstrate that the transformants generated with this system exhibit the expected cell type-specific expression, similar to what is observed with constitutively expressed native promoters. With this new system, cloning of inducible constructs is no longer limited to a few special cases but can be used as a standard approach when gene function is studied. In addition, we present a set of entry clones consisting of histochemical and fluorescent reporter variants designed for gene and promoter expression studies. PMID:26644504

  11. Building Blueprints: Making Music.

    ERIC Educational Resources Information Center

    College Planning & Management, 2002

    2002-01-01

    Depicts how Cornell University renovated its civil engineering and architecture building to include space for musical performances, teaching, and rehearsals. The article highlights the facility's contemporary design, which also compliments the form and massing of the original building. (GR)

  12. Building Design & Construction - Sustainability

    SciTech Connect

    2003-11-01

    Offers a brief history of green building; presents the results of a specially commissioned survey; and analyzes the chief trends, issues, and published research, based on interviews with dozens of experts and participants in green building.

  13. Building Materials Property Table

    SciTech Connect

    2010-04-16

    This information sheet describes a table of some of the key technical properties of many of the most common building materials taken from ASHRAE Fundamentals - 2001, Moisture Control in Buildings, CMHC, NRC/IRC, IEA Annex 24, and manufacturer data.

  14. Buildings interoperability landscape - Draft

    SciTech Connect

    Hardin, Dave B.; Stephan, Eric G.; Wang, Weimin; Corbin, Charles D.; Widergren, Steven E.

    2015-02-01

    Buildings are an integral part of our nation’s energy economy. The advancement in information and communications technology (ICT) has revolutionized energy management in industrial facilities and large commercial buildings. As ICT costs decrease and capabilities increase, buildings automation and energy management features are transforming the small-medium commercial and residential buildings sectors. A vision of a connected world in which equipment and systems within buildings coordinate with each other to efficiently meet their owners’ and occupants’ needs, and where buildings regularly transact business with other buildings and service providers (such as gas and electric service providers) is emerging. However, while the technology to support this collaboration has been demonstrated at various degrees of maturity, the integration frameworks and ecosystems of products that support the ability to easily install, maintain, and evolve building systems and their equipment components are struggling to nurture the fledging business propositions of their proponents.

  15. Green Building Standards

    EPA Pesticide Factsheets

    Many organizations have developed model codes or rating systems that communities may use to develop green building programs or revise building ordinances. Some of the major options are listed on this page.

  16. Better Buildings Challenge Overview

    SciTech Connect

    2011-06-01

    The Better Buildings Challenge is a national leadership initiative calling on corporate chief executive officers, university presidents, and state and local leaders to make a significant commitment to building energy efficiency.

  17. Building brands without mass media.

    PubMed

    Joachimsthaler, E; Aaker, D A

    1997-01-01

    Costs, market fragmentation, and new media channels that let customers bypass advertisements seem to be in league against the old ways of marketing. Relying on mass media campaigns to build strong brands may be a thing of the past. Several companies in Europe, making a virtue of necessity, have come up with alternative brand-building approaches and are blazing a trail in the post-mass-media age. In England, Nestlé's Buitoni brand grew through programs that taught the English how to cook Italian food. The Body Shop garnered loyalty with its support of environmental and social causes. Cadbury funded a theme park tied to its history in the chocolate business. Häagen-Dazs opened posh ice-cream parlors and got itself featured by name on the menus of fine restaurants. Hugo Boss and Swatch backed athletic or cultural events that became associated with their brands. The various campaigns shared characteristics that could serve as guidelines for any company hoping to build a successful brand: senior managers were closely involved with brand-building efforts; the companies recognized the importance of clarifying their core brand identity; and they made sure that all their efforts to gain visibility were tied to that core identity. Studying the methods of companies outside one's own industry and country can be instructive for managers. Pilot testing and the use of a single and continuous measure of brand equity also help managers get the most out of novel approaches in their ever more competitive world.

  18. Healthy Aging

    MedlinePlus

    ... About Us Contact Us Text size | Print | Healthy Aging This information in Spanish ( en español ) A healthy ... Aging email updates. Enter email address Submit Healthy Aging news Accessibility | Privacy policy | Disclaimers | FOIA | Link to ...

  19. Green Building Research Laboratory

    SciTech Connect

    Sailor, David Jean

    2013-12-29

    This project provided support to the Green Building Research Laboratory at Portland State University (PSU) so it could work with researchers and industry to solve technical problems for the benefit of the green building industry. It also helped to facilitate the development of PSU’s undergraduate and graduate-level training in building science across the curriculum.

  20. Concepts in Building Firesafety.

    ERIC Educational Resources Information Center

    Egan, M. David

    The goal of this book is to present in a graphical format the principles of design for building firesafety. The book's more than 270 illustrations represent the core of its coverage of factors affecting fire ignition and spread in buildings, building site planning for fire suppression and occupant rescue operations, protection by building…