Science.gov

Sample records for aging special emphasis

  1. 78 FR 5184 - Special Emphasis Panel Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-24

    ... HUMAN SERVICES Agency for Healthcare Research and Quality Special Emphasis Panel Meeting AGENCY: Agency... Healthcare Research and Quality (AHRQ) Special Emphasis Panel (SEP) meeting on ``Patient Centered Outcomes... contact: Mrs. Bonnie Campbell, Committee Management Officer, Office of Extramural Research, Education...

  2. 78 FR 63207 - Special Emphasis Panel; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-23

    ... HUMAN SERVICES Agency for Healthcare Research and Quality Special Emphasis Panel; Meeting AGENCY: Agency for Healthcare Research and Quality, HHS. ACTION: Notice. SUMMARY: In accordance with section 10(a)(2... Healthcare Research and Quality (AHRQ) Special Emphasis Panel (SEP) meeting on ``AHRQ RFA-HS-13-010,...

  3. Long-Term Potentiation at CA3–CA1 Hippocampal Synapses with Special Emphasis on Aging, Disease, and Stress

    PubMed Central

    Kumar, Ashok

    2011-01-01

    Synaptic plasticity in the mammalian central nervous system has been the subject of intense investigation for the past four decades. Long-term potentiation (LTP), a major reflection of synaptic plasticity, is an activity-driven long-lasting increase in the efficacy of excitatory synaptic transmission following the delivery of a brief, high-frequency train of electrical stimulation. LTP is regarded as a principal candidate for the cellular mechanisms involved in learning and offers an attractive hypothesis of how memories are constructed. There are a number of exceptional full-length reviews published on LTP; the current review intends to present an overview of the research findings regarding hippocampal LTP with special emphasis on aging, diseases, and psychological insults. PMID:21647396

  4. Space Construction System Analysis. Special Emphasis Studies

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Generic concepts were analyzed to determine: (1) the maximum size of a deployable solar array which might be packaged into a single orbit payload bay; (2) the optimal overall shape of a large erectable structure for large satellite projects; (3) the optimization of electronic communication with emphasis on the number of antennas and their diameters; and (4) the number of beams, traffic growth, and projections and frequencies were found feasible to package a deployable solar array which could generate over 250 kilowatts of electrical power. Also, it was found that the linear-shaped erectable structure is better for ease of construction and installation of systems, and compares favorably on several other counts. The study of electronic communication technology indicated that proliferation of individual satellites will crowd the spectrum by the early 1990's, so that there will be a strong tendency toward a small number of communications platforms over the continental U.S.A. with many antennas and multiple spot beams.

  5. Pycnodysostosis with Special Emphasis on Dentofacial Characteristics

    PubMed Central

    Khoja, Aisha; Fida, Mubassar; Shaikh, Attiya

    2015-01-01

    Pycnodysostosis is an autosomal recessive disorder that manifests as osteosclerosis of the skeleton due to the defective osteoclasts mediated bone turnover. The diagnosis of this disorder is established on the basis of its characteristic features and must be differentially diagnosed with other bone disorders. Dental surgeons should be aware of the limitations and possible adverse oral complications such as osteomyelitis of bone in these patients. This will guide them in planning realistic treatment goals. This paper reports the clinical and radiographic features of pycnodysostosis with the great emphasis on its dentofacial characteristics. The aim of this case report is to give an insight into the etiology, pathogenesis, and differential diagnosis of this disorder and to prepare the dentists and maxillofacial surgeons to overcome the challenges in treating these patients. PMID:26649209

  6. Pycnodysostosis with Special Emphasis on Dentofacial Characteristics.

    PubMed

    Khoja, Aisha; Fida, Mubassar; Shaikh, Attiya

    2015-01-01

    Pycnodysostosis is an autosomal recessive disorder that manifests as osteosclerosis of the skeleton due to the defective osteoclasts mediated bone turnover. The diagnosis of this disorder is established on the basis of its characteristic features and must be differentially diagnosed with other bone disorders. Dental surgeons should be aware of the limitations and possible adverse oral complications such as osteomyelitis of bone in these patients. This will guide them in planning realistic treatment goals. This paper reports the clinical and radiographic features of pycnodysostosis with the great emphasis on its dentofacial characteristics. The aim of this case report is to give an insight into the etiology, pathogenesis, and differential diagnosis of this disorder and to prepare the dentists and maxillofacial surgeons to overcome the challenges in treating these patients. PMID:26649209

  7. A Special Education Systems Simulation Model: Teacher Training Emphasis.

    ERIC Educational Resources Information Center

    Jones, Wayne; And Others

    The authors illustrate the application of a systems approach for educational decision-makers through utilization of a special education systems simulation model with emphasis on teacher training. It is noted that the model provides a procedure to answer "what if" type questions before actually implementing a proposed program. Discussed are the…

  8. Helminth parasites in ringed seals (Pusa hispida) from Svalbard, Norway with special emphasis on nematodes: variation with age, sex, diet, and location of host.

    PubMed

    Johansen, Carina E; Lydersen, Christian; Aspholm, Paul E; Haug, Tore; Kovacs, Kit M

    2010-10-01

    Complete gastrointestinal tracts from 257 ringed seals (Pusa hispida) from Svalbard, Norway, were examined for helminth parasites. Three different helminth groups were recorded (acanthocephalans 61.1%; nematodes 38%; cestodes 0.9%). Acanthocephalans (Polymorphidae) and cestodes (Anophryocephalus and Diphyllobothrium sp(p)., as well as unidentified species, were confined to the intestines. The anisakid nematodes Phocascaris phocae, Pseudoterranova sp(p)., Anisakis sp(p)., and Phocascaris/Contracaecum sp(p). were recorded in both stomachs and the anterior part of the small intestines. The abundance of nematodes and acanthocephalans varied significantly with sampling location of the seal hosts. This is likely due to the relative prevalence of Arctic versus Atlantic water in the different fjord systems, which strongly influences the age class and species of fish available as prey for the seals. Adult male ringed seals had significantly higher abundances of nematodes than did adult females or juveniles. Adult males also had significantly higher abundances of acanthocephalans than did adult females, but were not significantly different from juveniles in this regard. Nematode abundance increased significantly with age of male hosts, but this trend was lacking in female seals. Infection parameters appeared to be related to differences in the age of polar cod (Boreogadus saida) exploited by male, female, and juvenile seals.

  9. 76 FR 15984 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Combining...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-22

    ... Control Special Emphasis Panel (SEP): Combining Subjective and Objective Methods for Quantifying Contact... applications received in response to ``Combining Subjective and Objective Methods for Quantifying Contact Rates and Mixing Pattern in School-Aged Children, FOA CK11-006.'' Contact Person For More...

  10. An update on "special stain" histochemistry with emphasis on automation.

    PubMed

    Grogan, T; Reinhardt, K; Jaramillo, M; Lee, D

    2000-03-01

    For nearly 100 years, pathologists have utilized "special histochemical stains" to assist in tissue-based diagnosis. As illustrated in Figures 1 and 2, histochemical stains have been used to identify infectious microorganisms (e.g., Mycobacterium tuberculosis with acid-fast bacillus (AFB) stain), to detail inflammatory stromal or structural alterations (e.g., fibrosis in liver cirrhosis with Masson trichrome), to identify microanatomic sites of disease (e.g., basement membrane in glomerulonephritis with Jones methenamine silver), to identify abnormal chemical deposits (e.g., iron in hemochromatosis with Prussian blue stain), or abnormal immune deposits (e.g., amyloid via Congo red stain). The current surgical pathology laboratory may employ a repertoire of 20 to 25 "special stains" to ensure the full diagnostic complement. While the diagnostic repertoire and the biochemical recipes for the stains are now a well-established, codified part of surgical pathology, there is an ever-moving, leading edge of new developments including new reagents, applications, and methods. This review seeks to update the reader on some of the new applications including both new reagents and methods. Particular emphasis will be placed on the recent technologic advance of automating special stains in kinetic-mode (1-4). The authors consider in turn: 1. In brief, the "news" (recent literature review) of new staining applications; 2. In greater detail, two new applications for detection of Microsporidia and Helicobacer pylori; 3. The new technologic advancement of kinetic mode automation of special stains.

  11. Paediatric immunisation: special emphasis on measles and MMR vaccinations.

    PubMed

    Das, M K; Bhattacharyya, N

    2002-05-01

    The dictum, 'prevention is better than cure', is applicable to all ailments but it can be most easily followed for infectious diseases, increasing numbers of which are being contained by specific vaccinations since the first discovery of smallpox vaccine by Edward Jenner in 1796. Advances in immunology and laboratory techniques including cell culture, genetic engineering and animal experiments have contributed significantly to the production of more and more vaccines, used successfully in preventive programmes. Infectious diseases are widely prevalent in the developing countries. The child population is specially vulnerable to many of them. These infections contribute to high morbidity and mortality and immunisation programmes have been undertaken as preventive measures against them at the national level. Paediatricians and experts are actively engaged in formulating and improving these programmes as problems are faced in their implementation. Much new information is continuously being available in the literature, mostly in specialised journals. The general practitioners, particularly those serving in the remote and vast rural areas, are not likely to have access to these recent developments which they need for self-motivation in initiating the parents with confident advice to have their children properly immunised and also for tackling effectively any problem arising out of immunisation. This paper attempts to discuss the subject of paediatric immunisation with special emphasis being laid on measles and MMR vaccinations. PMID:12418635

  12. 76 FR 27327 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Combining...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-11

    ... Control Special Emphasis Panel (SEP): Combining Subjective and Objective Methods for Quantifying Contact... 3, 2011 (Closed). Place: Teleconference. Contact Person For More Information: Gregory Anderson,...

  13. 75 FR 13560 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Knowledge...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-22

    ... Control Special Emphasis Panel (SEP): Knowledge Synthesis Center for Evaluating Genomic Application in..., discussion, and evaluation of applications received in response to ``Knowledge Synthesis Center...

  14. 78 FR 43003 - Biomedical Laboratory Research and Development Service, Special Emphasis Panel-Amyotrophic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-18

    ... Lateral Sclerosis (ALS) Brain Bank, Notice of Meeting The Department of Veterans Affairs (VA) gives notice under the Federal Advisory Committee Act, 5 U.S.C. App., that the Special Emphasis Panel--ALS Brain Bank...) (6) and (9)(B). The purpose of this Special Emphasis Panel is to review the VA ALS Brain Bank for...

  15. 75 FR 77645 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pregnancy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-13

    ... Control Special Emphasis Panel (SEP): Pregnancy Risk Assessment Monitoring System (PRAMS), DP11-001 Panel..., discussion, and evaluation of ``Pregnancy Risk Assessment Monitoring System (PRAMS), DP11-001 Panel...

  16. 76 FR 5379 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pregnancy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    ... Control Special Emphasis Panel (SEP): Pregnancy Risk Assessment Monitoring System (PRAMS), DP11-001 Panels... Be Discussed: The meeting will include the initial review, discussion, and evaluation of...

  17. 76 FR 4911 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Occupational...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-27

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Occupational Safety and Health Educational Research Centers, Program... recommendations to the Disease, Disability, and Injury Prevention and Control SEP: Occupational Safety and...

  18. 75 FR 4406 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Occupational...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Occupational Safety and Health Training Projects Grants, Request for... Disease, Disability, and Injury Prevention and Control SEP: Occupational Safety and Health...

  19. 75 FR 9423 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Impact of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-02

    ... Control Special Emphasis Panel (SEP): Impact of Japanese Encephalitis Vaccination in Cambodia, Funding... Vaccination in Cambodia, FOA CK10-003.'' Contact Person for More Information: Gregory Anderson, M.S.,...

  20. 75 FR 12243 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Translating...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-15

    ... Control Special Emphasis Panel (SEP): Translating Research Into Healthy Eye and Vision Loss Prevention... Research into Healthy Eye and Vision Loss Prevention, RFA DP 10- 004.'' Contact Person for More...

  1. 76 FR 3909 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Family...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-21

    ... Control Special Emphasis Panel (SEP): Family History and Diamond Blackfan Anemia, DD11- 010, Initial... ``Family History and Diamond Blackfan Anemia, DD11-010, initial review.'' Contact Person for...

  2. 75 FR 10490 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Member...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-08

    ... Control Special Emphasis Panel (SEP): Member Conflict Review, Program Announcement (PA) 07-318, Initial... review, discussion, and evaluation of ``Member Conflict Review, PA 07- 318.'' Contact Person for...

  3. 75 FR 6675 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Human...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-10

    ..., National Center for HIV, Hepatitis and Sexually Transmitted Diseases Prevention, 1600 Clifton Road, NE... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Human Immunodeficiency Virus (HIV) Prevention Projects for...

  4. 75 FR 52356 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: National Human...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-25

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: National Human Immunodeficiency Virus (HIV) Behavioral Surveillance... Disease Registry. Dated: August 18, 2010. Elaine L. Baker, Director, Management Analysis and...

  5. 78 FR 62636 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns...

  6. 78 FR 60875 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns...

  7. 78 FR 9926 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns...

  8. 78 FR 60877 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns...

  9. 78 FR 37542 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns...

  10. 77 FR 61756 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-11

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns...

  11. 75 FR 78999 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Maternal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... Control Special Emphasis Panel (SEP): Maternal Vitamin D Status and Preterm Birth, DP11-002, Initial... ``Maternal Vitamin D Status and Preterm Birth, DP11-002, initial review.'' Contact Person for...

  12. 76 FR 4911 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Centers of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-27

    ... Control Special Emphasis Panel (SEP): Centers of Excellence To Promote a Healthier Workforce, Request for... Excellence to Promote a Healthier Workforce, RFA OH11-001.'' Contact Person for More Information:...

  13. Intelligent noncompliance with special emphasis on the elderly.

    PubMed

    Weintraub, M

    1981-01-01

    Intelligently noncompliant patients alter their prescribed therapy on a rational basis that often represents advanced therapeutic principles. The literature contains many examples of patients who alter their medication but still have good treatment outcome. Doses are altered to avoid adverse effects or because the dose was excessive or inconvenient. When compliance studies are done in a large heterogeneous group, the rates for different age groups are almost always similar. Health professionals have devised compliance-ensuring strategies such as educational programs and modification of the regimen. Use of compliance-ensuring strategies, however, opposes the current trend which advocates a more direct, active patient participation in treatment decisions.

  14. Optical radiation and the eyes with special emphasis on children.

    PubMed

    Söderberg, Per G

    2011-12-01

    The Sun is the most abundant source of optical radiation for the child eye. New hand-held visible lasers are a threat to the child eye. Some scientific data suggest that near infrared radiation may cause cumulative damage in the ocular lens. The child eye usually is exposed to ambient solar radiation, gazing at the horizon. Ambient Sun ultraviolet radiation (UVR) exposure to the child is complex due to atmospheric scattering and strong dependence on background reflection. Solar exposure causes biological damage, only by photochemical mechanisms. UVR exposure to a child eye is mainly a threat to the anterior segment of the eye, but also age dependently to the retina. Above threshold exposure to UVR, for short delay onset of damage, causes a toxic reaction on the surface of the eye, snow blindness, and cataract. Sub-threshold daily exposure to UVR over decades is associated with several ocular surface pathologies and eye lid cancer. Visible radiation is a threat to the retina. A single above threshold exposure, for short delay onset of damage to the retina causes immediate photochemical Type II retinal damage, Sun blindness. A single exposure of the retina to a very high intensity laser beam may cause thermal or thermo-mechanical damage in the retina. In environments with high irradiance of optical radiation, the child eye should be protected. Legislation and public information is required for avoidance of damage from high intensity laser systems. More research is urgently needed to exclude the potential hazard of near infrared radiation.

  15. 76 FR 4703 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pregnancy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pregnancy Risk Assessment Monitoring System (PRAMS), DP11-001...

  16. 75 FR 77645 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pregnancy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pregnancy Risk Assessment Monitoring System (PRAMS), DP11-001 Panel D, Initial Review In accordance...

  17. 76 FR 4911 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Building Capacity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-27

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Building Capacity for State-Based Occupational Health Surveillance... Advisory Committee Act (Pub. L. 92-463), the Centers for Disease Control and Prevention (CDC) announces...

  18. 76 FR 13621 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Family...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Family History and Diamond Blackfan Anemia, DD11- 010,...

  19. 76 FR 367 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Minority HIV...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-04

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Minority HIV/AIDS Research Initiative (MARI) To Build Capacity in Black and Hispanic Communities and Among Black and Hispanic Researchers To Conduct...

  20. 75 FR 46952 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): National...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-04

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): National Human Immunodeficiency Virus (HIV) Behavioral Surveillance... Federal Advisory Committee Act (Pub. L. 92-463), the Centers for Disease Control and Prevention...

  1. 75 FR 78997 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pilot...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... Control Special Emphasis Panel (SEP): Pilot Longitudinal Data Collection To Inform Public Health--Fragile... review, discussion, and evaluation of ``Pilot Longitudinal Data Collection to Inform Public Health... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  2. 76 FR 20355 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Funding...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-12

    ... Control Special Emphasis Panel (SEP): Funding Opportunity Announcement (FOA), Initial Review The meeting... (MOPH) (U01),'' FOA GH11-002, initial review. In accordance with Section 10(a)(2) of the Federal... Thailand by the Ministry of Public Health (MOPH) (U01),'' FOA GH11-002, initial review. Contact Person...

  3. 76 FR 20355 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Funding...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-12

    ... Control Special Emphasis Panel (SEP): Funding Opportunity Announcement (FOA) DD11-009, Initial Review The...,'' FOA DD11-009, initial review. In accordance with Section 10(a)(2) of the Federal Advisory Committee... Prevention of Complications of Bleeding,'' FOA DD11-009, initial review. Contact Person for More...

  4. 76 FR 21749 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Funding...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-18

    ... Control Special Emphasis Panel (SEP): Funding Opportunity Announcement (FOA) CK11- 0010101PPHF11, Initial... Ventilator-Associated Pneumonia: Reducing Burden and Demonstrating Preventability,'' FOA CK11- 0010101PPHF11... for Ventilator-Associated Pneumonia: Reducing Burden and Demonstrating Preventability,'' FOA...

  5. 76 FR 19995 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Funding...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-11

    ... Control Special Emphasis Panel (SEP): Funding Opportunity Announcement (FOA), Initial Review The meeting announced below concerns ``National Spina Bifida Registry Longitudinal Data Collection and Evaluation,'' FOA... Longitudinal Data Collection and Evaluation,'' FOA DD11-005, initial review. Contact Person for...

  6. 76 FR 13619 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Funding...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-14

    ... Control Special Emphasis Panel (SEP): Funding Opportunity Announcement (FOA), Initial Review The meeting... Announcement (FOA) GH11-003, and Research Activities in Support of Malaria Prevention and Control in the Republic of Uganda as Part of the President's Malaria Initiative, FOA GH11-004, initial review....

  7. 76 FR 19996 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Funding...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-11

    ... Control Special Emphasis Panel (SEP): Funding Opportunity Announcement (FOA), Initial Review The meeting announced below concerns ``Longitudinal Study of a Population-based Cohort of People with Lupus,'' FOA DP11... People with Lupus,'' FOA DP11-004, initial review. Contact Person for More Information: Brenda...

  8. 76 FR 82299 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Data...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-30

    ... to ``Data Coordinating Center for Autism and Other Developmental Disabilities Research and... Control Special Emphasis Panel (SEP): Data Coordinating Center for Autism and Other Developmental Disabilities Research and Epidemiologic Studies, RFA DD12-001, Initial Review In accordance with Section...

  9. 78 FR 78966 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Capacity Building Assistance for High Impact...

  10. 75 FR 28625 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Assessment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-21

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Assessment of Post-Treatment Lyme Disease Syndrome, Funding...-Treatment Lyme Disease Syndrome,'' FOA CK10-004. Contact Person for More Information: Maurine Goodman,...

  11. 75 FR 28261 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Improved...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-20

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Improved Diagnostics for Lyme Borreliosis, Funding Opportunity... Committee Act (Pub. L. 92-463), the Centers for Disease Control and Prevention (CDC) announces...

  12. 76 FR 67458 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-01

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Emerging..., Georgia 30337, Telephone: (770) 997-1100. Contact Person For More Information: Amy Yang, Ph.D.,...

  13. 77 FR 34045 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-08

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Initial Review The meeting announced below concerns Cooperative Research... Control and Prevention (CDC) announces the aforementioned meeting: Times and Dates: 8 a.m.-5 p.m., July...

  14. 77 FR 5026 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Occupational... Section 10(a)(2) of the Federal Advisory Committee Act (Pub. L. 92-463), the Centers for Disease...

  15. 77 FR 31018 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-24

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Member Conflict... the Federal Advisory Committee Act (Pub. L. 92-463), the Centers for Disease Control and...

  16. 78 FR 66937 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review Notice of Cancellation: This notice concerns..., initial review, published in the Federal Register on October 2, 2013 (FR Volume 78, Number 191, Page...

  17. 78 FR 66937 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Occupational... 10(a)(2) of the Federal Advisory Committee Act (Pub. L. 92-463), the Centers for Disease Control...

  18. 78 FR 60878 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Health...

  19. 78 FR 60878 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns National...

  20. 76 FR 28790 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Member...

  1. 77 FR 44618 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns the World...

  2. 78 FR 35035 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial review The meeting announced below concerns Centers...

  3. 77 FR 48986 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Member...

  4. 76 FR 52330 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Member...

  5. 78 FR 36785 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Centers...

  6. 78 FR 60879 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns National...

  7. 76 FR 10908 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Maternal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Maternal Vitamin D Status and Preterm Birth, DP11-002,...

  8. Exercise and sleep in aging: emphasis on serotonin.

    PubMed

    Melancon, M O; Lorrain, D; Dionne, I J

    2014-10-01

    Reductions in central serotonin activity with aging might be involved in sleep-related disorders in later life. Although the beneficial effects of aerobic exercise on sleep are not new, sleep represents a complex recurring state of unconsciousness involving many lines of transmitters which remains only partly clear despite intense ongoing research. It is known that serotonin released into diencephalon and cerebrum might play a key inhibitory role to help promote sleep, likely through an active inhibition of supraspinal neural networks. Several lines of evidence support the stimulatory effects of exercise on higher serotonergic pathways. Hence, exercise has proved to elicit acute elevations in forebrain serotonin concentrations, an effect that waned upon cessation of exercise. While adequate exercise training might lead to adaptations in higher serotonergic networks (desensitization of forebrain receptors), excessive training has been linked to serious brain serotonergic maladaptations accompanied by insomnia. Dietary supplementation of tryptophan (the only serotonin precursor) is known to stimulate serotonergic activity and promote sleep, whereas acute tryptophan depletion causes deleterious effects on sleep. Regarding sleep-wake regulation, exercise has proved to accelerate resynchronization of the biological clock to new light-dark cycles following imposition of phase shifts in laboratory animals. Noteworthy, the effect of increased serotonergic transmission on wake state appears to be biphasic, i.e. promote wake and thereafter drowsiness. Therefore, it might be possible that acute aerobic exercise would act on sleep by increasing activity of ascending brain serotonergic projections, though additional work is warranted to better understand the implication of serotonin in the exercise-sleep axis.

  9. Exercise and sleep in aging: emphasis on serotonin.

    PubMed

    Melancon, M O; Lorrain, D; Dionne, I J

    2014-10-01

    Reductions in central serotonin activity with aging might be involved in sleep-related disorders in later life. Although the beneficial effects of aerobic exercise on sleep are not new, sleep represents a complex recurring state of unconsciousness involving many lines of transmitters which remains only partly clear despite intense ongoing research. It is known that serotonin released into diencephalon and cerebrum might play a key inhibitory role to help promote sleep, likely through an active inhibition of supraspinal neural networks. Several lines of evidence support the stimulatory effects of exercise on higher serotonergic pathways. Hence, exercise has proved to elicit acute elevations in forebrain serotonin concentrations, an effect that waned upon cessation of exercise. While adequate exercise training might lead to adaptations in higher serotonergic networks (desensitization of forebrain receptors), excessive training has been linked to serious brain serotonergic maladaptations accompanied by insomnia. Dietary supplementation of tryptophan (the only serotonin precursor) is known to stimulate serotonergic activity and promote sleep, whereas acute tryptophan depletion causes deleterious effects on sleep. Regarding sleep-wake regulation, exercise has proved to accelerate resynchronization of the biological clock to new light-dark cycles following imposition of phase shifts in laboratory animals. Noteworthy, the effect of increased serotonergic transmission on wake state appears to be biphasic, i.e. promote wake and thereafter drowsiness. Therefore, it might be possible that acute aerobic exercise would act on sleep by increasing activity of ascending brain serotonergic projections, though additional work is warranted to better understand the implication of serotonin in the exercise-sleep axis. PMID:25104243

  10. Special Issue: The Silicon Age

    NASA Astrophysics Data System (ADS)

    Kittler, Martin; Yang, Deren

    2006-03-01

    The present issue of physica status solidi (a) contains a collection of articles about different aspects of current silicon research and applications, ranging from basic investigations of mono- and polycrystalline silicon materials and nanostructures to technologies for device fabrication in silicon photovoltaics, micro- and optoelectronics. Guest Editors are Martin Kittler and Deren Yang, the organizers of a recent Sino-German symposium held in Cottbus, Germany, 19-24 September 2005.The cover picture shows four examples of The Silicon Age: the structure of a thin film solar cell on low-cost SSP (silicon sheet from powder) substrate (upper left image) [1], a high-resolution transmission electron microscopy image and diffraction pattern of a single-crystalline Si nanowire (upper right) [2], a carrier lifetime map from an n-type multicrystalline silicon wafer after gettering by a grain boundary (lower left) [3], and a scanning acoustic microscopy image of a bonded 150 mm diameter wafer pair (upper right) [4].

  11. Geostationary platform systems concepts definition follow-on study. Volume 2A: Technical Task 2 LSST special emphasis

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The results of the Large Space Systems Technology special emphasis task are presented. The task was an analysis of structural requirements deriving from the initial Phase A Operational Geostationary Platform study.

  12. Diabetic Nephropathy in American Indians, with a Special Emphasis on the Pima Indians

    PubMed Central

    Pavkov, Meda E.; Knowler, William C.; Hanson, Robert L.; Nelson, Robert G.

    2012-01-01

    Diabetes affects American Indians disproportionately compared with other racial/ethnic groups in the United States and is almost exclusively type 2 diabetes. Much of our knowledge about diabetes in American Indians comes from studies in a few tribes. The most extensively studied American Indians are the Pima Indians from the Gila River Indian Community in Arizona, who participated in a longitudinal study of diabetes and its complications between 1965 and 2007. They have one of the highest reported incidence and prevalence of type 2 diabetes in the world, and kidney disease attributable to diabetes is a major cause of morbidity and mortality. In this article, we examine the course, determinants, and trends of diabetic kidney disease in American Indians, with special emphasis on studies conducted in the Pima Indians. We also review therapeutic strategies for managing diabetic kidney disease. PMID:18990306

  13. Data analysis in craniofacial biology with special emphasis on longitudinal studies.

    PubMed

    Kowalski, C J

    1993-03-01

    Recommendations are made for strengthening data description and analysis in craniofacial biology. Special emphasis is placed on longitudinal data, and PC programs for accomplishing appropriate analyses in this context are described and made available to interested readers. Some more general recommendations are treated in less detail. These include the effective description of data using stem-and-leaf displays and/or boxplots, the use of decision-analytic methods in the management of patients with dentofacial deformities, and the valid application of certain statistical methods in single-subject studies. Finally, it is conjectured that computer-intensive methods such as randomization tests and jackknifing will play an increasingly prominent role in craniofacial research. PMID:8452829

  14. Remediation of BTEX and trichloroethene. Current knowledge with special emphasis on phytoremediation.

    PubMed

    Collins, Chris; Laturnus, Frank; Nepovim, Ales

    2002-01-01

    The widespread use of industrial chemicals in our highly industrialized society has often caused contamination of large terrestrial and marine areas due to the deliberate and accidental release of organic pollutants into the soil and groundwater. In this review, environmental problems arising from the use of chlorinated solvents and BTEX compounds are described, and an overview about active management strategies for remediation with special emphasis on phytoremediation are presented to achieve a reduction of the total mass of chlorinated solvents and BTEX compounds in contaminated areas. Phytoremediation has been proposed as an efficient, low-cost remediation technique to restore areas contaminated with chlorinated solvents and BTEX compounds. The feasibility of phytoremediation as a remediation tool for these compounds is discussed with particular reference to the uptake and metabolism of these compounds, and a future perspective on the use of phytoremediation for the removal of chlorinated solvents and BTEX compounds is given.

  15. Morphological Dynamics of Mitochondria – A Special Emphasis on Cardiac Muscle Cells

    PubMed Central

    Hom, Jennifer; Sheu, Shey-Shing

    2010-01-01

    Mitochondria play a critical role in cellular energy metabolism, Ca2+ homeostasis, reactive oxygen species generation, apoptosis, aging, and development. Many recent publications have shown that a continuous balance of fusion and fission of these organelles is important in maintaining their proper function. Therefore, there is a steep correlation between the form and function of mitochondria. Many major proteins involved in mitochondrial fusion and fission have been identified in different cell types, including heart. However, the functional role of mitochondrial dynamics in the heart remains, for the most part, unexplored. In this review we will cover the recent field of mitochondrial dynamics and its physiological and pathological implications, with a particular emphasis on the experimental and theoretical basis of mitochondrial dynamics in the heart. PMID:19281816

  16. [Cervicogenic proprioceptive vertigo: etiopathogenesis, clinical manifestations, diagnosis and therapy with special emphasis on manual therapy].

    PubMed

    Grgić, Vjekoslav

    2006-01-01

    Cervical proprioceptive system (CPS) consisting of mechanoreceptors of cervical intervertebral joints, mechanoreceptors of neck muscles and ligament's insertions, muscle spindles located in deep short muscles of cervical spine and sensitive fibers connecting neck's proprioceptors with neurons of cornu posteriori of spinal cord, plays an essential part in maintaining bodily balance. CPS, via tractus spinovestibularis, is connected to vestibular nuclei. Clinical and neurophysiological studies have shown that functional disorders and/or organic lesions of CPS cause identical symptoms as vestibular diseases: vertigo, nystagmus and balance disorders. Dysfunction (functional blockade) of craniocervical joints is the most frequent cause of cervicogenic proprioceptive vertigo (CPV). The constant tension of the capsule of a blocked joint irritates mechanoreceptors protecting the joint's capsules. The increased activity of mechanoreceptors results in confusion of vestibular system. That is, the impulses from the blocked craniocervical joints do not correspond to the impulses from the vestibular organ and other sensory systems that take part in maintaining bodily balance. The disharmony of impulses results in an inadequate vestibulo-spinal and vestibulo-ocular reaction manifesting as vertigo and nystagmus. Hyperactivity of craniocervical mechanoreceptors also causes disturbances in reflex regulation of postural muscle tonus manifesting as "general instability". Knowledge of CPV as a separate clinical entity is important from diagnostical and therapeutical aspect. As it concerns a peripheral vestibular disorder still unknown to a wider circle of physicians, the article describes etiopathogenesis, clinical manifestations, diagnosis and therapy of CPV with special emphasis on manual therapy.

  17. Differentiation processes in the amphibian brain with special emphasis on heterochronies.

    PubMed

    Schmidt, A; Roth, G

    1996-01-01

    Amphibians and caecilians exhibit a great variety of adult morphologies, life histories, and developmental strategies (biphasic development, direct development, viviparity, and neoteny). While early brain development and the differentiation of neural tissues in the three amphibian orders follow a basic pattern, differences exist in the onset and offset as well as the rate of growth and differentiation processes. These differences are described within a phylogenetic framework, and special emphasis is laid on the relationship between altered ontogenies and phylogenetic diversity. We concentrate on ontogenetic differentiation processes in the motor, olfactory, and visual system. We discuss the morphological consequences of secondary simplification of the brain in the context of paedomorphosis, which has happened several times independently among amphibians and consists in the abbreviation or truncation of late developmental processes. We deal with the cellular and molecular basis of brain development and the consequences for the adult nervous system in representative species of the three amphibian orders. Our analysis reveals that differences in brain morphology are largely due to heterochrony (i.e., the desynchronization of ontogenetic processes), a phenomenon that in turn is related to changes in genome sizes and life histories. PMID:8843653

  18. 75 FR 55803 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Epi-Centers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-14

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Epi-Centers for the Prevention of Healthcare- Associated...

  19. 75 FR 69686 - Disease, Disability, and Injury Prevention and Control; Special Emphasis Panel: Epi-Centers for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control; Special Emphasis Panel: Epi-Centers for the Prevention of Healthcare-Associated...

  20. Determination of lactic acid with special emphasis on biosensing methods: A review.

    PubMed

    Pundir, Chandra S; Narwal, Vinay; Batra, Bhawna

    2016-12-15

    Lactic acid (2-Hydroxypropanoic acid) is generated from pyruvic acid under anaerobic condition in skeletal muscles, brain, red blood cells, and kidney. Lactate in normal human subjects get cleared very quickly at a rate of 320mmol/L/hr, mostly by liver metabolism and re-conversion of lactate back to pyruvate. Measurement of lactate level in serum is required for the differential diagnosis and medical management of hyperlactatemia, cardiac arrest and resuscitation, sepsis, reduced renal excretion, hypoxia induced cancer, decreased extra hepatic metabolism, intestinal infarction and lactic acidosis. Determination of lactate is also important in dairy products and beverages to access their quality. Among the various methods available for detection of lactate, most are complicated, nonspecific, less sensitive and require time-consuming sample pretreatment, expensive instrumental set-up and trained persons to operate, specifically for chromatographic methods. Biosensing methods overcome these drawbacks, as these are simple, fast, specific and highly sensitive. Lactate biosensors reported so far, work optimally within 3-180s, between pH, 5.5-8.5 and temperature 22°C to 37°C and lactate concentration ranging from 10 to 2000µM. These biosensors have been employed to measure lactate level in embryonic cell culture, beverages, urine, and serum samples and reused upto 200-times within a period of 7-216 days. This review presents the principles, merits and demerits of various analytical methods for lactate determination with special emphasis on lactate biosensors. The future perspective for improvement of analytic performance of lactate biosensors are discussed.

  1. Determination of lactic acid with special emphasis on biosensing methods: A review.

    PubMed

    Pundir, Chandra S; Narwal, Vinay; Batra, Bhawna

    2016-12-15

    Lactic acid (2-Hydroxypropanoic acid) is generated from pyruvic acid under anaerobic condition in skeletal muscles, brain, red blood cells, and kidney. Lactate in normal human subjects get cleared very quickly at a rate of 320mmol/L/hr, mostly by liver metabolism and re-conversion of lactate back to pyruvate. Measurement of lactate level in serum is required for the differential diagnosis and medical management of hyperlactatemia, cardiac arrest and resuscitation, sepsis, reduced renal excretion, hypoxia induced cancer, decreased extra hepatic metabolism, intestinal infarction and lactic acidosis. Determination of lactate is also important in dairy products and beverages to access their quality. Among the various methods available for detection of lactate, most are complicated, nonspecific, less sensitive and require time-consuming sample pretreatment, expensive instrumental set-up and trained persons to operate, specifically for chromatographic methods. Biosensing methods overcome these drawbacks, as these are simple, fast, specific and highly sensitive. Lactate biosensors reported so far, work optimally within 3-180s, between pH, 5.5-8.5 and temperature 22°C to 37°C and lactate concentration ranging from 10 to 2000µM. These biosensors have been employed to measure lactate level in embryonic cell culture, beverages, urine, and serum samples and reused upto 200-times within a period of 7-216 days. This review presents the principles, merits and demerits of various analytical methods for lactate determination with special emphasis on lactate biosensors. The future perspective for improvement of analytic performance of lactate biosensors are discussed. PMID:27476060

  2. Applying Continuous Quality Improvement Principles in Secondary School Vocational Education, with Emphasis on Special Populations.

    ERIC Educational Resources Information Center

    McLean, Gary N.

    1993-01-01

    Principles of quality management applicable to education for secondary special populations include process orientation, cascading, top commitment, vertical/horizontal communication, continuous improvement, shared vision, primacy of customers, investment in people, constancy of purpose, and shared goal setting. (JOW)

  3. 78 FR 19490 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-01

    ... an Evidenced-- Informed Mall Walking Program Resource Guide, Special Interest Project (SIP)13-070..., discussion, and evaluation of ``Development of an Evidenced--Informed Mall Walking Program Resource...

  4. Planning and Implementing Career Education for the Special Student, with Emphasis on the Leisure Occupations.

    ERIC Educational Resources Information Center

    Vinton, Dennis A.; And Others

    A program of career education for exceptional students in the leisure occupations is described. It is explained that the book is designed for regular and special class teachers. Chapters one and two present information on career education principles and implementation. Chapters three through five deal with practical teaching concerns. Behavioral…

  5. The Generalization of Behavior Modification Procedures: A Review--with Special Emphasis on Classroom Applications

    ERIC Educational Resources Information Center

    Wildman, Robert W., II; Wildman, Robert W.

    1975-01-01

    Reports of the use of behavior modification in the classroom are reviewed, with special attention given to whether or not generalization of the effects of the behavior modification programs was obtained. The authors develop a set of 15 proposed "rules" for obtaining generalization of the effects of behavior modification procedures. (Author)

  6. 78 FR 19489 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-01

    ... Cancer Screening: Informed Decision Making and Smoking Cessation, Special Interest Project (SIP)13-068; and Tobacco Use Quitline Registries for Continuously Engaging Participants in Cessation, SIP13-073..., discussion, and evaluation of ``Low Dose CT Lung Cancer Screening: Informed Decision Making and...

  7. 78 FR 19489 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-01

    ... Feasibility of a National Surveillance System for Breast, Cervical and Colorectal Cancer Screening, Special Interest Projects (SIP)13-065; and Using Small Media to Increase Breast and Cervical Cancer Population... National Surveillance System for Breast, Cervical and Colorectal Cancer Screening, SIP13-065; and...

  8. Progress in muscular dystrophy research with special emphasis on gene therapy

    PubMed Central

    SUGITA, Hideo; TAKEDA, Shin’ichi

    2010-01-01

    Duchenne muscular dystrophy (DMD) is an X-linked, progressive muscle-wasting disease caused by mutations in the DMD gene. Since the disease was described by physicians in the 19th century, information about the subject has been accumulated. One author (Sugita) was one of the coworkers who first reported that the serum creatine kinase (CK) level is elevated in progressive muscular dystrophy patients. Even 50 years after that first report, an elevated serum CK level is still the most useful marker in the diagnosis of DMD, a sensitive index of the state of skeletal muscle, and useful to evaluate therapeutic effects. In the latter half of this article, we describe recent progress in the therapy of DMD, with an emphasis on gene therapies, particularly exon skipping. PMID:20689232

  9. Radiation risk modeling of thyroid cancer with special emphasis on the Chernobyl epidemiological data.

    PubMed

    Walsh, L; Jacob, P; Kaiser, J C

    2009-10-01

    Two recent studies analyzed thyroid cancer incidence in Belarus and Ukraine during the period from 1990 to 2001, for the birth cohort 1968 to 1985, and the related (131)I exposure associated with the Chernobyl accident in 1986. Contradictory age-at-exposure and time-since-exposure effect modifications of the excess relative risk (ERR) were reported. The present study identifies the choice of baseline modeling method as the reason for the conflicting results. Various quality-of-fit criteria favor a parametric baseline model to various categorical baseline models. The model with a parametric baseline results in a decrease of the ERR by a factor of about 0.2 from an age at exposure of 5 years to an age at exposure of 15 years (for a time since exposure of 12 years) and a decrease of the ERR from a time since exposure of 4 years to a time since exposure of 14 years of about 0.25 (for an age at exposure of 10 years). Central ERR estimates (of about 20 at 1 Gy for an age at exposure of 10 years and an attained age of 20 years) and their ratios for females compared to males (about 0.3) turn out to be relatively independent of the modeling. Excess absolute risk estimates are also predicted to be very similar from the different models. Risk models with parametric and categorical baselines were also applied to thyroid cancer incidence among the atomic bomb survivors. For young ages at exposure, the ERR values in the model with a parametric baseline are larger. Both data sets cover the period of 12 to 15 years since exposure. For this period, higher ERR values and a stronger age-at-exposure modification are found for the Chernobyl data set. Based on the results of the study, it is recommended to test parametric and categorical baseline models in risk analyses. PMID:19772472

  10. Expression of P-glycoprotein in high grade osteosarcomas with special emphasis on chondroblastic subtype.

    PubMed

    Radig, K; Häckel, C; Herting, J; Oda, Y; Mittler, U; Neumann, W; Roessner, A

    1997-02-01

    The development of chemoresistance is one of the major clinical problems in the therapy of malignant bone tumors in childhood. The expression of membrane-bound P-glycoprotein turned out to be an essential factor in the evidence of resistant tumor cells. To investigate the significance of multidrug resistance in the prognosis of highly malignant osteosarcomas, the immunohistologic expression of P-glycoprotein was investigated in the tumor tissue of 52 patients under special consideration of the histologic subtype. The data were compared with the histologic regression grade in the resection specimen and correlated with clinical data. Formalin-fixed, paraffin-embedded tissue and, additionally, fresh frozen material taken from the primary biopsy were stained using monoclonal antibody JSB1. 29 (55%) of the tumors investigated were P-glycoprotein positive. Considering the response to chemotherapy, no conclusion could be drawn regarding P-glycoprotein expression, regression grade in the resection specimens, and the clinical follow-up. P-glycoprotein was detected in only 52% of the non-responders. A positive reaction was also evidenced in 59% of the patients with high chemosensitivity. A comparison of the histologic subtypes yielded a significant result in the chondroblastic osteosarcomas. 11 of 12 cases showed a strong expression of P-glycoprotein. Most of the cases were non-responders, and using Kaplan-Meier live tables, an unfavorable clinical outcome could be demonstrated. Possibly, chondroblastic tumors have a special position among osteosarcomas because of their differentiation. PMID:9065577

  11. 77 FR 39498 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-03

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... Project (SIP): Assessing the Pregnancy Prevention Needs of HIV-Infected Young Women of Reproductive Age...) of the Federal Advisory Committee Act (Pub. L. 92-463), the Centers for Disease Control...

  12. Neuroanatomical dichotomy of sexual behaviors in rodents: a special emphasis on brain serotonin.

    PubMed

    Angoa-Pérez, Mariana; Kuhn, Donald M

    2015-09-01

    and male sexual behavior and the participation of the serotonin system in the modulation of these behaviors, with emphasis on rodents.

  13. Neuroanatomical dichotomy of sexual behaviors in rodents: a special emphasis on brain serotonin

    PubMed Central

    Angoa-Pérez, Mariana; Kuhn, Donald M.

    2016-01-01

    sexual behavior and the participation of the serotonin system in the modulation of these behaviors with emphasis on rodents. PMID:26110223

  14. Demand forecasting using fuzzy neural computation, with special emphasis on weekend and public holiday forecasting

    SciTech Connect

    Srinivasan, D.; Chang, C.S.; Liew, A.C.

    1995-11-01

    This paper describes the implementation and forecasting results of a hybrid fuzzy neural technique, which combines neural network modeling, and techniques from fuzzy logic and fuzzy set theory for electric load forecasting. The strengths of this powerful technique lie in its ability to forecast accurately on weekdays, as well as, on weekends, public holidays, and days before and after public holidays. Furthermore, use of fuzzy logic effectively handles the load variations due to special events. The Fuzzy-Neural Network (FNN) has been extensively tested on actual data obtained from a power system for 24-hour ahead prediction based on forecast weather information. Very impressive results, with an average error of 0.62% on weekdays, 0.83% on Saturdays and 1.17% on Sundays and public holidays have been obtained. This approach avoids complex mathematical calculations and training on many years of data, and is simple to implement on a personal computer.

  15. Satellite Power Systems (SPS) concept definition study, exhibit C. Volume 5: Special emphasis studies

    NASA Technical Reports Server (NTRS)

    Hanley, G.

    1979-01-01

    Specific areas were analyzed and identified as high priority for more in-depth analysis. These areas were: (1) rectenna constructability; (2) satellite constructability; (3) support systems constructability; (4) space environmental analysis, and (5) special end-to-end analyses. Baseline requirements specified coplanar solar blankets and an end mounted antenna, utilizing either GaAlAs solar cells and employing a CR of 2, or Si cells. Several configurations were analyzed. Utilizing the preferred configuration as a baseline, a satellite construction base was defined, precursor operations incident to establishment of orbital support facilities identified, and the satellite construction sequence and procedures developed. Since the baseline specifies sixty instead of one hundred and twenty satellites to be constructed in a thirty year period, mass flow to orbit requirements were revised and new traffic models established. Launch site requirements (exclusive of actual launch operations) in terms of manpower and building space were defined.

  16. The complexities of defining optimal sleep: empirical and theoretical considerations with a special emphasis on children.

    PubMed

    Blunden, Sarah; Galland, Barbara

    2014-10-01

    The main aim of this paper is to consider relevant theoretical and empirical factors defining optimal sleep, and assess the relative importance of each in developing a working definition for, or guidelines about, optimal sleep, particularly in children. We consider whether optimal sleep is an issue of sleep quantity or of sleep quality. Sleep quantity is discussed in terms of duration, timing, variability and dose-response relationships. Sleep quality is explored in relation to continuity, sleepiness, sleep architecture and daytime behaviour. Potential limitations of sleep research in children are discussed, specifically the loss of research precision inherent in sleep deprivation protocols involving children. We discuss which outcomes are the most important to measure. We consider the notion that insufficient sleep may be a totally subjective finding, is impacted by the age of the reporter, driven by socio-cultural patterns and sleep-wake habits, and that, in some individuals, the driver for insufficient sleep can be viewed in terms of a cost-benefit relationship, curtailing sleep in order to perform better while awake. We conclude that defining optimal sleep is complex. The only method of capturing this elusive concept may be by somnotypology, taking into account duration, quality, age, gender, race, culture, the task at hand, and an individual's position in both sleep-alert and morningness-eveningness continuums. At the experimental level, a unified approach by researchers to establish standardized protocols to evaluate optimal sleep across paediatric age groups is required.

  17. Retained placenta in Friesian mares: incidence, and potential risk factors with special emphasis on gestational length.

    PubMed

    Sevinga, M; Barkema, H W; Stryhn, H; Hesselink, J W

    2004-04-01

    During the foaling seasons of 1999 and 2000, the incidence of retained placenta in 495 normal parturitions of 436 Friesian brood mares was studied. Retained placenta was defined as a failure to expel all fetal membranes within 3 h of the delivery of the foal. Furthermore, the sex of the foal, month of breeding, sire and dam's sire, age of the mare, and time of day of foaling, were studied as factors that might be associated with retained placenta in Friesian mares after normal foalings, and with gestational length. The analysis was carried out using marginal logistic regression, and mixed linear regression, respectively. The incidence of retained placenta was 54%. Mean length of gestation was 331.6 days. Colts were carried 1.5 days longer than fillies. Mares bred in July-September had a 4-day shorter gestation period (329 days) than mares bred earlier in the year. There was a mare, sire, and dam's sire effect on gestational length, and a mare effect on the occurrence of retained placenta. Mares foaling at 4 and >17 years of age, tended to have a lower incidence of retained placenta than mares foaling at 5-17 years of age. No association was found between the occurrence of retained placenta, and gestational length, sex of the foal, month of breeding, dam's sire, and time of day of foaling. It was concluded that the observed high incidence of retained placenta indicates that the Friesian breed of horses has a higher risk for retained placenta than other breeds of horses.

  18. Modelling of ICRF heating in DEMO with special emphasis on bulk ion heating

    SciTech Connect

    Gallart, Dani; Mantsinen, Mervi; Kazakov, Yevgen

    2015-12-10

    Ion cyclotron resonance frequency (ICRF) heating is one of the auxiliary heating schemes presently envisaged for ITER and DEMO. In this paper we analyse the potential of ICRF waves to heat the fuel ions in DEMO. Our analysis is carried out for the DEMO1 Reference Scenario from October 2013 (B = 6.8 T, I = 18.6 MA, R = 9.25 m, a = 2.64 m) optimized for a maximum pulse length of 2.3 hrs using the ICRF modelling codes PION and TORIC. We focus on second harmonic heating of tritium and fundamental minority heating of {sup 3}He ions (with a few percent of {sup 3}He) in a 50%:50% D-T plasma. The dependence of the ICRF characteristics and the ICRF-accelerated ions on the ICRF and plasma parameters is investigated, giving special attention to the DEMO design point at a core plasma temperature of 30 keV and an electron density of 1.2·10{sup 20} m{sup −3}.

  19. The Role of MicroRNAs in Diabetic Complications—Special Emphasis on Wound Healing

    PubMed Central

    Moura, João; Børsheim, Elisabet; Carvalho, Eugenia

    2014-01-01

    Overweight and obesity are major problems in today’s society, driving the prevalence of diabetes and its related complications. It is important to understand the molecular mechanisms underlying the chronic complications in diabetes in order to develop better therapeutic approaches for these conditions. Some of the most important complications include macrovascular abnormalities, e.g., heart disease and atherosclerosis, and microvascular abnormalities, e.g., retinopathy, nephropathy and neuropathy, in particular diabetic foot ulceration. The highly conserved endogenous small non-coding RNA molecules, the micro RNAs (miRNAs) have in recent years been found to be involved in a number of biological processes, including the pathogenesis of disease. Their main function is to regulate post-transcriptional gene expression by binding to their target messenger RNAs (mRNAs), leading to mRNA degradation, suppression of translation or even gene activation. These molecules are promising therapeutic targets and demonstrate great potential as diagnostic biomarkers for disease. This review aims to describe the most recent findings regarding the important roles of miRNAs in diabetes and its complications, with special attention given to the different phases of diabetic wound healing. PMID:25268390

  20. Protein secretion biotechnology in Gram-positive bacteria with special emphasis on Streptomyces lividans.

    PubMed

    Anné, Jozef; Vrancken, Kristof; Van Mellaert, Lieve; Van Impe, Jan; Bernaerts, Kristel

    2014-08-01

    Proteins secreted by Gram-positive bacteria are released into the culture medium with the obvious benefit that they usually retain their native conformation. This property makes these host cells potentially interesting for the production of recombinant proteins, as one can take full profit of established protocols for the purification of active proteins. Several state-of-the-art strategies to increase the yield of the secreted proteins will be discussed, using Streptomyces lividans as an example and compared with approaches used in some other host cells. It will be shown that approaches such as increasing expression and translation levels, choice of secretion pathway and modulation of proteins thereof, avoiding stress responses by changing expression levels of specific (stress) proteins, can be helpful to boost production yield. In addition, the potential of multi-omics approaches as a tool to understand the genetic background and metabolic fluxes in the host cell and to seek for new targets for strain and protein secretion improvement is discussed. It will be shown that S. lividans, along with other Gram-positive host cells, certainly plays a role as a production host for recombinant proteins in an economically viable way. This article is part of a Special Issue entitled: Protein trafficking and secretion in bacteria. Guest Editors: Anastassios Economou and Ross Dalbey.

  1. The regulatory system in europe with special emphasis on allergen products.

    PubMed

    Lorenz, A R; Luttkopf, D; Seitz, R; Vieths, S

    2008-01-01

    For each medicinal product quality, safety and efficacy have to be proven to obtain a marketing authorisation. The national competent health authorities and the European Medicines Agency (EMEA) with support of the Heads of Medicines Agencies (HMA) work together to grant marketing authorisations for medicinal products. Several regulatory procedures to apply for a marketing authorisation in the European Community (EC) and associated countries exist. After approval by a national procedure a medicinal product can be marketed in only one country. If a medicinal product should enter the markets of two or more European countries of choice the application has to undergo the Mutual Recognition Procedure (MRP) or the Decentralised Procedure (DCP). A marketing authorisation granted by the Centralised Procedure (CP) is valid in the whole EC. The CP is mandatory for certain medicinal products, for example all products derived from recombinant DNA technology including recombinant allergens. The guidance documents applicable to allergen products comprise general as well as product-specific guidelines such as the Note for Guidance on Allergen Products and the Monograph on Allergen Products of the European Pharmacopoeia. So-called 'named patient products' have a special status and are applied to patients without having a marketing authorisation. Recombinant allergens as medicinal products are insufficiently covered by the existing allergen product-specific guidelines, but product-specific guidelines are in the development stage. PMID:18648190

  2. A clinical study on oral lichen planus with special emphasis on hyperpigmentation

    PubMed Central

    Chitturi, Ravi Teja; Sindhuja, Pandian; Parameswar, R. Arjun; Nirmal, Ramdas Madhavan; Reddy, B. Venkat Ramana; Dineshshankar, Janardhanam; Yoithapprabhunath, Thukanayakanpalayam Ragunathan

    2015-01-01

    Background: Oral lichen planus (OLP) is a unique disorder affecting generally the older age group. Numerous studies have been done on various aspects of OLP such as pathogenesis, rate of malignant transformation, etc. However, very few studies are available with respect to clinical features especially association of hyperpigmentation and OLP. This study aims at studying the clinical aspects of OLP and study the association between hyperpigmentation and OLP in a south Indian population. Materials and Methods: A total of 58 patients with OLP who attended the outpatient department of our institution were included in the study and a complete history, followed by thorough intraoral examination was done. All the data were recorded and assessed for statistical analysis using SPSS software. Results: We found that the male to female ratio affected with OLP was 1:1 and the most common form of OLP that was seen was the reticular subtype. Also, buccal mucosa was the most common affected site and more than 60% patients had hyperpigmentation associated with the site affected by OLP. We found a statistically significant relation between the reticular type of OLP and the older age group (51–70 years) with hyperpigmentation. Conclusion: Although further studies are required to say anything conclusively, post-inflammatory changes occurring the mucosa due to OLP could be a cause for hyperpigmentation in the sites affected. PMID:26538905

  3. Computational Age Dating of Special Nuclear Materials

    SciTech Connect

    None, None

    2012-06-30

    This slide-show presented an overview of the Constrained Progressive Reversal (CPR) method for computing decays, age dating, and spoof detecting. The CPR method is: Capable of temporal profiling a SNM sample; Precise (compared with known decay code, such a ORIGEN); Easy (for computer implementation and analysis). We have illustrated with real SNM data using CPR for age dating and spoof detection. If SNM is pure, may use CPR to derive its age. If SNM is mixed, CPR will indicate that it is mixed or spoofed.

  4. Isolation of compound and CNS depressant activities of Mikania scandens Willd with special emphasis to brain biogenic amines in mice.

    PubMed

    Pal, Dilipkumar; Mazumder, Upal Kanti

    2014-12-01

    Mikania scandens, a twining herb that grows as a weed in India and Bangladesh is used as vegetables and is a good source of vitamin A, C, B complex, mikanin, sesquiterpenes, betasitosterin, stigmasterol and friedelin. The present communication reports CNS depressant activities with special emphasis to brain biogenic amines in mice. Ethanol extract of leaves of M. scandens (EEMS) was prepared by Soxhalation and analyzed chemically. EEMS potentiated sleeping time induced by pentobarbitone, diazepam and meprobamate and showed significant reduction in the number of writhes and stretches. EEMS caused significant protection against pentylene tetrazole-induced convulsion and increased catecholamines and brain amino acids level significantly. Results showed that EEMS produced good CNS depressant effects in mice. PMID:25651612

  5. [The federal participation law : New requirements for needs assessment with special emphasis on medical rehabilitation services].

    PubMed

    Schubert, Michael; Schian, Marcus; Viehmeier, Sarah

    2016-09-01

    The federal participation law (Bundesteilhabegesetz - BTHG) is one of the largest efforts in the last 15 years to reform the legal participation rights of people with disabilities. In particular, a number of enhancements are planned in the overall benefits law in Part 1 of Book IX in the Social Code (Sozialgesetzbuch - SGB), which applies to all rehabilitation carriers including general provisions and standards for needs assessment. This paper deals with the implications of these provisions and interacting standards, based on the draft bill of April 2016.The discussion takes place against the background of the regulatory objectives formulated in the ministerial draft itself, jurisprudential expertise on the effects of the current legal norms of the SGB IX as well as relevant professional political developments and statements by various stakeholders.The analysis shows a clear political commitment to increase the requirements for needs assessment in the overall law of the SGB IX and to express these more effectively. The draft bill seeks not only to modify procedures subsequent to the application for rehabilitation benefits, but also to precisely set out provisions on instruments for needs assessment in a new § 13. Common principles for these instruments of needs assessment should increase the cooperation, coordination and convergence among rehabilitation carriers.Nevertheless, with regard to the proposed regulatory texts, there is doubt that the objectives set by the draft bill itself will be achieved. For example, the required common principles for needs assessment are to be agreed upon based on the existing special legislation for the different rehabilitation carriers, without the SGB IX setting its own binding standards or framework principles. In addition, it lacks clear legal guidelines for the professional practice to make use of the bio-psycho-social model of the WHO and the ICF in the process of needs assessment. As a consequence the ICF cannot

  6. [The federal participation law : New requirements for needs assessment with special emphasis on medical rehabilitation services].

    PubMed

    Schubert, Michael; Schian, Marcus; Viehmeier, Sarah

    2016-09-01

    The federal participation law (Bundesteilhabegesetz - BTHG) is one of the largest efforts in the last 15 years to reform the legal participation rights of people with disabilities. In particular, a number of enhancements are planned in the overall benefits law in Part 1 of Book IX in the Social Code (Sozialgesetzbuch - SGB), which applies to all rehabilitation carriers including general provisions and standards for needs assessment. This paper deals with the implications of these provisions and interacting standards, based on the draft bill of April 2016.The discussion takes place against the background of the regulatory objectives formulated in the ministerial draft itself, jurisprudential expertise on the effects of the current legal norms of the SGB IX as well as relevant professional political developments and statements by various stakeholders.The analysis shows a clear political commitment to increase the requirements for needs assessment in the overall law of the SGB IX and to express these more effectively. The draft bill seeks not only to modify procedures subsequent to the application for rehabilitation benefits, but also to precisely set out provisions on instruments for needs assessment in a new § 13. Common principles for these instruments of needs assessment should increase the cooperation, coordination and convergence among rehabilitation carriers.Nevertheless, with regard to the proposed regulatory texts, there is doubt that the objectives set by the draft bill itself will be achieved. For example, the required common principles for needs assessment are to be agreed upon based on the existing special legislation for the different rehabilitation carriers, without the SGB IX setting its own binding standards or framework principles. In addition, it lacks clear legal guidelines for the professional practice to make use of the bio-psycho-social model of the WHO and the ICF in the process of needs assessment. As a consequence the ICF cannot

  7. Ethical considerations in the prevention and management of genetic disorders with special emphasis on religious considerations.

    PubMed

    Albar, Mohammed A

    2002-06-01

    Genetic diseases include not only single gene disorders, but multifactorial, somatic cell genetic disorders, mitochondrial and even chromosomal. One in 4 adults will suffer from a multifactorial or a somatic cell genetic disease. The common diseases in the community have a hereditary component namely diabetes mellitus, hypertension, ischemic heart diseases and many types of cancer. Even monogenic diseases which affect a small number of the newborns (2%-3%), have a greater impact on childhood diseases up to age 15 years. Therefore, it is imperative to scrutinize the available methods of prevention and management of genetic disorders, their ethical implications, and since east Mediterranean region is mainly occupied by Arabs and muslims, religious considerations become of paramount importance. Islam differs from many other religions in providing a complete code of life, which encompasses the secular with spiritual, the mundane with the celestial and hence forms the basis of the ethical, moral and even juridical attitudes and laws towards any problem or situation. Islamic teachings carry a great deal of instructions for health promotion and disease prevention including hereditary and genetic disorders. This review discusses how the Islamic teachings play an important role in the prevention and management of genetic disorders and the type of ethical implications involved in such management namely premarital medical examination, the question of consanguinity, the genetic counseling, the question of preimplantation diagnosis, the question of abortion and the offering of alternative ways of reproduction.

  8. 20 CFR 404.383 - Special age 72 payment amounts.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Special age 72 payment amounts. 404.383 Section 404.383 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance Benefits; Period...

  9. 20 CFR 404.383 - Special age 72 payment amounts.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Special age 72 payment amounts. 404.383 Section 404.383 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance Benefits; Period...

  10. 20 CFR 404.383 - Special age 72 payment amounts.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Special age 72 payment amounts. 404.383 Section 404.383 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance Benefits; Period...

  11. 20 CFR 404.383 - Special age 72 payment amounts.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Special age 72 payment amounts. 404.383 Section 404.383 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance Benefits; Period...

  12. 20 CFR 404.383 - Special age 72 payment amounts.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Special age 72 payment amounts. 404.383 Section 404.383 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance Benefits; Period...

  13. Treatment of antimony mine drainage: challenges and opportunities with special emphasis on mineral adsorption and sulfate reducing bacteria.

    PubMed

    Li, Yongchao; Hu, Xiaoxian; Ren, Bozhi

    2016-01-01

    The present article summarizes antimony mine distribution, antimony mine drainage generation and environmental impacts, and critically analyses the remediation approach with special emphasis on iron oxidizing bacteria and sulfate reducing bacteria. Most recent research focuses on readily available low-cost adsorbents, such as minerals, wastes, and biosorbents. It is found that iron oxides prepared by chemical methods present superior adsorption ability for Sb(III) and Sb(V). However, this process is more costly and iron oxide activity can be inhibited by plenty of sulfate in antimony mine drainage. In the presence of sulfate reducing bacteria, sulfate can be reduced to sulfide and form Sb(2)S(3) precipitates. However, dissolved oxygen and lack of nutrient source in antimony mine drainage inhibit sulfate reducing bacteria activity. Biogenetic iron oxide minerals from iron corrosion by iron-oxidizing bacteria may prove promising for antimony adsorption, while the micro-environment generated from iron corrosion by iron oxidizing bacteria may provide better growth conditions for symbiotic sulfate reducing bacteria. Finally, based on biogenetic iron oxide adsorption and sulfate reducing bacteria followed by precipitation, the paper suggests an alternative treatment for antimony mine drainage that deserves exploration. PMID:27148704

  14. Selenol protecting groups in organic chemistry: special emphasis on selenocysteine Se-protection in solid phase peptide synthesis.

    PubMed

    Flemer, Stevenson

    2011-04-18

    The appearance of selenium in organic synthesis is relatively rare, and thus examples in the literature pertaining to the masking of its considerable reactivity are similarly uncommon. Greene's Protecting Groups in Organic Synthesis, the standard reference for the state of the art in this arena, offers no entries for selenium protective methodology, in stark comparison to its mention of the great variety of protecting groups germane to its chalcogen cousin sulfur. This scarcity of Se-protection methods makes it no less interesting and pertinent toward the construction of selenium-containing organic systems which do indeed require the iterative blocking and de-blocking of selenol functionalities. A selenium-containing system which is especially relevant is selenocysteine, as its use in Solid Phase Peptide Synthesis requires extensive protection of its selenol side chain. This review will attempt to summarize the current state of understanding with regard to selenium protection protocol in organic synthesis. Moreover, it will provide a special emphasis on selenocysteine side chain protection, comprising both the breadth of functionality used for this purpose as well as methods of deprotection.

  15. A review of Brucella infection in marine mammals, with special emphasis on Brucella pinnipedialis in the hooded seal (Cystophora cristata).

    PubMed

    Nymo, Ingebjørg H; Tryland, Morten; Godfroid, Jacques

    2011-01-01

    Brucella spp. were isolated from marine mammals for the first time in 1994. Two novel species were later included in the genus; Brucella ceti and Brucella pinnipedialis, with cetaceans and seals as their preferred hosts, respectively. Brucella spp. have since been isolated from a variety of marine mammals. Pathological changes, including lesions of the reproductive organs and associated abortions, have only been registered in cetaceans. The zoonotic potential differs among the marine mammal Brucella strains. Many techniques, both classical typing and molecular microbiology, have been utilised for characterisation of the marine mammal Brucella spp. and the change from the band-based approaches to the sequence-based approaches has greatly increased our knowledge about these strains. Several clusters have been identified within the B. ceti and B. pinnipedialis species, and multiple studies have shown that the hooded seal isolates differ from other pinniped isolates. We describe how different molecular methods have contributed to species identification and differentiation of B. ceti and B. pinnipedialis, with special emphasis on the hooded seal isolates. We further discuss the potential role of B. pinnipedialis for the declining Northwest Atlantic hooded seal population. PMID:21819589

  16. Evolution, molecular epidemiology and perspectives on the research of taeniid parasites with special emphasis on Taenia solium.

    PubMed

    Bobes, Raúl J; Fragoso, Gladis; Fleury, Agnès; García-Varela, Martín; Sciutto, Edda; Larralde, Carlos; Laclette, Juan P

    2014-04-01

    Human cysticercosis is known since old historical times in Greece and China; however, human infections by tapeworms have accompanied human beings for more that hundred thousand years. The disease is tightly bound to poverty and lack of hygiene, and has been eradicated in developed countries, but continues being a public health problem in developing countries of Latin-American, Sub-Saharan Africa and Asia, and is also remerging in a number of non endemic countries. It is considered a neglected disease. Here we revise a number of key scientific contributions on taeniid biology that open new avenues for more effective approaches to the control of cysticercosis. The evolution of flatworms and class Cestoda is analyzed, with special emphasis on the emergence of taeniid parasites and the colonization of the human species by tapeworms. The complex molecular host-parasite interplay in this relationship as result of co-evolution between two distantly related organisms. The relevant host and parasite's factors, in the prospect of identifying species-specific molecular markers useful in epidemiological studies carried out in endemic countries. The new possibilities arising with the characterization of the genomes for several species of tapeworms, including a deeper understanding of these organisms, as well as improved tools for diagnosis, vaccination and drug treatment. The need to revise the current control and management strategies for this tropical neglected disease.

  17. Treatment of antimony mine drainage: challenges and opportunities with special emphasis on mineral adsorption and sulfate reducing bacteria.

    PubMed

    Li, Yongchao; Hu, Xiaoxian; Ren, Bozhi

    2016-01-01

    The present article summarizes antimony mine distribution, antimony mine drainage generation and environmental impacts, and critically analyses the remediation approach with special emphasis on iron oxidizing bacteria and sulfate reducing bacteria. Most recent research focuses on readily available low-cost adsorbents, such as minerals, wastes, and biosorbents. It is found that iron oxides prepared by chemical methods present superior adsorption ability for Sb(III) and Sb(V). However, this process is more costly and iron oxide activity can be inhibited by plenty of sulfate in antimony mine drainage. In the presence of sulfate reducing bacteria, sulfate can be reduced to sulfide and form Sb(2)S(3) precipitates. However, dissolved oxygen and lack of nutrient source in antimony mine drainage inhibit sulfate reducing bacteria activity. Biogenetic iron oxide minerals from iron corrosion by iron-oxidizing bacteria may prove promising for antimony adsorption, while the micro-environment generated from iron corrosion by iron oxidizing bacteria may provide better growth conditions for symbiotic sulfate reducing bacteria. Finally, based on biogenetic iron oxide adsorption and sulfate reducing bacteria followed by precipitation, the paper suggests an alternative treatment for antimony mine drainage that deserves exploration.

  18. Ecology and control of the sand fly vectors of Leishmania donovani in East Africa, with special emphasis on Phlebotomus orientalis.

    PubMed

    Elnaiem, Dia-Eldin A

    2011-03-01

    A literature review is provided on the state of knowledge of the ecology and control of the sand fly vectors of Leishmania donovani in East Africa, with a special emphasis on Phlebotomus orientalis. Visceral leishmaniasis caused by L. donovani is a major health problem in several areas in East Africa. Studies conducted in the past 70 years identified P. orientalis Parrot and P. martini Parrot as the principal vectors of L. donovani in Sudan, Ethiopia and Kenya and P. celiae Minter as the secondary vector of the parasite in one focus in Ethiopia. Findings on sand fly fauna and other circumstantial evidence indicate that P. martini is also responsible for transmission of L. donovani in VL endemic foci of Somalia and Uganda. Several studies showed that P. orientalis occupy distinct habitat characterized by black cotton soil and Acacia seyal-Balanites aegyptiaca vegetation, whereas P. martini and P. celiae are associated with termite mounds. Little knowledge exists on effective control measures of sand fly vectors of L. donovani in East Africa. However, recent evidence showed that use of insecticide impregnated bednets and insect repellents may reduce exposure to the bites of P. orientalis. PMID:21366778

  19. A review of Brucella infection in marine mammals, with special emphasis on Brucella pinnipedialis in the hooded seal (Cystophora cristata)

    PubMed Central

    2011-01-01

    Brucella spp. were isolated from marine mammals for the first time in 1994. Two novel species were later included in the genus; Brucella ceti and Brucella pinnipedialis, with cetaceans and seals as their preferred hosts, respectively. Brucella spp. have since been isolated from a variety of marine mammals. Pathological changes, including lesions of the reproductive organs and associated abortions, have only been registered in cetaceans. The zoonotic potential differs among the marine mammal Brucella strains. Many techniques, both classical typing and molecular microbiology, have been utilised for characterisation of the marine mammal Brucella spp. and the change from the band-based approaches to the sequence-based approaches has greatly increased our knowledge about these strains. Several clusters have been identified within the B. ceti and B. pinnipedialis species, and multiple studies have shown that the hooded seal isolates differ from other pinniped isolates. We describe how different molecular methods have contributed to species identification and differentiation of B. ceti and B. pinnipedialis, with special emphasis on the hooded seal isolates. We further discuss the potential role of B. pinnipedialis for the declining Northwest Atlantic hooded seal population. PMID:21819589

  20. 77 FR 61613 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ... Committee: National Institute on Aging Special Emphasis Panel; Systems Biology of the Aged in Yeast. Date...: National Institute on Aging Special Emphasis Panel; ROS and Aging II. Date: November 7, 2012. Time: 12:30...

  1. Integrated plant nutrient system - with special emphasis on mineral nutriton and biofertilizers for Black pepper and cardamom - A review.

    PubMed

    K P, Sangeeth; R, Suseela Bhai

    2016-05-01

    Integrated Plant Nutrition System (IPNS) as a concept and farm management strategy embraces and transcends from single season crop fertilization efforts to planning and management of plant nutrients in crop rotations and farming systems on a long-term basis for enhanced productivity, profitability and sustainability. It is estimated that about two-thirds of the required increase in crop production in developing countries will have to come from yield increases from lands already under cultivation. IPNS enhances soil productivity through a balanced use of soil nutrients, chemical fertilizers, combined with organic sources of plant nutrients, including bio-inoculants and nutrient transfer through agro-forestry systems and has adaptation to farming systems in both irrigated and rainfed agriculture. Horticultural crops, mainly plantation crops, management practices include application of fertilizers and pesticides which become inevitable due to the depletion of soil organic matter and incidence of pests and diseases. The extensive use of chemical fertilizers in these crops deteriorated soil health that in turn affected the productivity. To revitalize soil health and to enhance productivity, it is inexorable to enrich the soil using microorganisms. The lacunae observed here is the lack of exploitation of indigenous microbes having the potential to fix atmospheric nitrogen (N) and to solubilize Phosphorus (P) and Potassium (K). The concept of biofertilizer application appears to be technically simple and financially feasible, but the task of developing biofertilizers with efficient strains in appropriate combinations in a consortia mode is not easier. More than developing consortia, a suitable delivery system to discharge the microbial inoculants warranted much effort. This review focuses on the integrated plant nutrition system incorporating biofertilizer with special emphasis on developing and formulating biofertilizer consortium. PMID:25834919

  2. [Lipidic pattern of 25 Mexican marine fishes with special emphasis in their n-3 fatty acids as nutraceuticals components].

    PubMed

    Castro-González, María Isabel; Ojeda, Anayté; Silencio, José Luis; Cassis, Lorena; Ledesma, Hector; Pérez-Gil, Fernando

    2004-09-01

    The aim of this study was to characterize and to evaluate the lipidic composition of mexican marine fishes with special emphasis in n-3 fatty acids as nutraceuticals. The edible portion of 25 species: humidity (H), crude protein (CP), total lipids (TL) and fatty acids (FA). The average content (g/100g edible portion) of H was 75.20, PC was 18.40, TL was 3.60. Four n-3 FA were identified in all the samples and they were found in the next abundance order (mg/100g edible portion): C22:6n-3 (DHA)(229.60), C20:5 n-3 (EPA)(52.10), C18:3 n-3 (ALA)(11.80) and C20:3 n-3 (2.25). By their origin and climate there were no difference. By their biologycal classification, n-3 FA content was higher in bony fishes than cartilaginous fishes. It was detected a proportional relation with the n-3 FA concentration and total lipid content. According to their ecotic distribution there were numerical differences in DHA content (mg/100g edible portion) between pelagics (420.70), benthopelagics (125.30) and demersals fishes (225.40). Fatty fishes had higher content of EPA and DHA (mg/100g edible portion) (109.27 and 552.72) than semifatty fishes (56.12 and 226.29) and leanness (15.95 and 96.52), respectively. Bony, fatty and pelagic fishes had a higher content of EPA+DHA. According with the international recommendation values (200 to 600 mg EPA+DHA/day) the 44% of the analyzed species could be considered as functional foods due to their high content of EPA + DHA in a range of 220 to 1300 mg/100g.

  3. Integrated plant nutrient system - with special emphasis on mineral nutriton and biofertilizers for Black pepper and cardamom - A review.

    PubMed

    K P, Sangeeth; R, Suseela Bhai

    2016-05-01

    Integrated Plant Nutrition System (IPNS) as a concept and farm management strategy embraces and transcends from single season crop fertilization efforts to planning and management of plant nutrients in crop rotations and farming systems on a long-term basis for enhanced productivity, profitability and sustainability. It is estimated that about two-thirds of the required increase in crop production in developing countries will have to come from yield increases from lands already under cultivation. IPNS enhances soil productivity through a balanced use of soil nutrients, chemical fertilizers, combined with organic sources of plant nutrients, including bio-inoculants and nutrient transfer through agro-forestry systems and has adaptation to farming systems in both irrigated and rainfed agriculture. Horticultural crops, mainly plantation crops, management practices include application of fertilizers and pesticides which become inevitable due to the depletion of soil organic matter and incidence of pests and diseases. The extensive use of chemical fertilizers in these crops deteriorated soil health that in turn affected the productivity. To revitalize soil health and to enhance productivity, it is inexorable to enrich the soil using microorganisms. The lacunae observed here is the lack of exploitation of indigenous microbes having the potential to fix atmospheric nitrogen (N) and to solubilize Phosphorus (P) and Potassium (K). The concept of biofertilizer application appears to be technically simple and financially feasible, but the task of developing biofertilizers with efficient strains in appropriate combinations in a consortia mode is not easier. More than developing consortia, a suitable delivery system to discharge the microbial inoculants warranted much effort. This review focuses on the integrated plant nutrition system incorporating biofertilizer with special emphasis on developing and formulating biofertilizer consortium.

  4. Applied Mathematics in EM Studies with Special Emphasis on an Uncertainty Quantification and 3-D Integral Equation Modelling

    NASA Astrophysics Data System (ADS)

    Pankratov, Oleg; Kuvshinov, Alexey

    2016-01-01

    second part, we summarize modern trends in the development of efficient 3-D EM forward modelling schemes with special emphasis on recent advances in the integral equation approach.

  5. 75 FR 8374 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... Committee: National Institute on Aging Special Emphasis Panel, New Invertebrate Models for the Biology of... Institute on Aging Special Emphasis Panel, Behavioral Economics, Health and Aging. Date: March 31,...

  6. An In-Depth Review of the Current Practica, Associated with Early Childhood through Twelfth Grade Special Education Programs, for the Benefit of Higher Education Programs, with an Emphasis in Obtaining a M.Ed. in Special Education

    ERIC Educational Resources Information Center

    Cady, Jennifer

    2010-01-01

    In order to guide organizational growth in the Master's in Education with an emphasis in Special Education program, offered at Southwestern College, an in-depth qualitative study was conducted with participants from three specific realms located in the state of Kansas. Participants from the Kansas State Department of Education, Southwestern…

  7. Preparing Research Leaders for Special Education: A Ph.D. Program with an Emphasis in Applied Behavior Analysis.

    ERIC Educational Resources Information Center

    Heward, William L.; And Others

    1995-01-01

    An Ohio State University doctoral program for special education leadership personnel emphasizing applied behavior analysis is described. The program features intensive formal coursework, special topic seminars, participation in three research studies prior to dissertation, supervised college teaching and advising experiences, and a 10-week summer…

  8. A Quantitative Analysis of Special Needs with Emphasis on Speech and Hearing in the Boston Public Schools.

    ERIC Educational Resources Information Center

    Wilson, Mazzie R.; Stewart, James Monroe

    1983-01-01

    The primary prototypes and educational goals used to educate Boston, Massachusetts, public school children with special needs (mainstreamed children) were analyzed and a demographic profile was developed. The results indicated that the special needs of the school children were not in close proportion to their racial distribution. (Author/SEW)

  9. Caregivers' Experience during Their Children's Transition Process from Early Childhood Special Education Services to School-Aged Special Education Services

    ERIC Educational Resources Information Center

    Hicks, Linda Yvonne

    2011-01-01

    This study investigates caregivers' perceptions of the transition process for children transitioning from Early Childhood Special Education (ECSE) to School Age Special Education services (SA). Interest in this topic developed during the researcher's 18 years of experience as an Itinerant Early Childhood Special Education Teacher during which she…

  10. 42 CFR 408.45 - Deduction from age 72 special payments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 2 2011-10-01 2011-10-01 false Deduction from age 72 special payments. 408.45... § 408.45 Deduction from age 72 special payments. (a) Deduction of premiums. SMI premiums are deducted from age 72 special payments made under section 228 of the Act or the payments are withheld...

  11. 42 CFR 408.45 - Deduction from age 72 special payments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Deduction from age 72 special payments. 408.45... § 408.45 Deduction from age 72 special payments. (a) Deduction of premiums. SMI premiums are deducted from age 72 special payments made under section 228 of the Act or the payments are withheld...

  12. 42 CFR 408.45 - Deduction from age 72 special payments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 2 2012-10-01 2012-10-01 false Deduction from age 72 special payments. 408.45... § 408.45 Deduction from age 72 special payments. (a) Deduction of premiums. SMI premiums are deducted from age 72 special payments made under section 228 of the Act or the payments are withheld...

  13. 42 CFR 408.45 - Deduction from age 72 special payments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 2 2013-10-01 2013-10-01 false Deduction from age 72 special payments. 408.45... § 408.45 Deduction from age 72 special payments. (a) Deduction of premiums. SMI premiums are deducted from age 72 special payments made under section 228 of the Act or the payments are withheld...

  14. 75 FR 5601 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-03

    ... Aging Special Emphasis Panel, Alzheimer's Disease Genetics. Date: March 4, 2010. Time: 7:30 p.m. to 8:30... Institute on Aging Special Emphasis Panel, Drug Development for Alzheimer's Disease. Date: March 10,...

  15. Seasonal dynamics of zooplankton in Columbia–Snake River reservoirs,with special emphasis on the invasive copepod Pseudodiaptomus forbesi

    USGS Publications Warehouse

    Emerson, Joshua E; Bollens, Stephen M; Counihan, Timothy D.

    2014-01-01

    The Asian copepod Pseudodiaptomus forbesi has recently become established in the Columbia River. However, little is known about its ecology and effects on invaded ecosystems. We undertook a 2-year (July 2009 to June 2011) field study of the mesozooplankton in four reservoirs in the Columbia and Snake Rivers, with emphasis on the relation of the seasonal variation in distribution and abundance of P. forbesi to environmental variables. Pseudodiaptomus forbesi was abundant in three reservoirs; the zooplankton community of the fourth reservoir contained no known non-indigenous taxa. The composition and seasonal succession of zooplankton were similar in the three invaded reservoirs: a bloom of rotifers occurred in spring, native cyclopoid and cladoceran species peaked in abundance in summer, and P. forbesi was most abundant in late summer and autumn. In the uninvaded reservoir, total zooplankton abundance was very low year-round. Multivariate ordination indicated that temperature and dissolved oxygen were strongly associated with zooplankton community structure, with P. forbesi appearing to exhibit a single generation per year . The broad distribution and high abundance of P. forbesi in the Columbia–Snake River System could result in ecosystem level effects in areas intensively managed to improve conditions for salmon and other commercially and culturally important fish species. 

  16. Phytoplankton dynamics with a special emphasis on harmful algal blooms in the Mar Piccolo of Taranto (Ionian Sea, Italy).

    PubMed

    Caroppo, Carmela; Cerino, Federica; Auriemma, Rocco; Cibic, Tamara

    2016-07-01

    The response of phytoplankton assemblages to the closure of urban sewage outfalls (USOs) was examined for the Mar Piccolo of Taranto (Mediterranean Sea), a productive semi-enclosed coastal marine ecosystem devoted to shellfish farming. Phytoplankton dynamics were investigated in relation to environmental variables, with a particular emphasis on harmful algal blooms (HABs). Recent analyses evidenced a general reduction of the inorganic nutrient loads, except for nitrates and silicates. Also phytoplankton biomass (chlorophyll a) and abundances were characterized by a decrease of the values, except for the inner area of the basin (second inlet). The phytoplankton composition changed, with nano-sized species, indicators of oligotrophic conditions, becoming dominant over micro-sized species. If the closure of the USOs affected phytoplankton dynamics, however, it did not preserve the Mar Piccolo from HABs and anoxia crises. About 25 harmful species have been detected throughout the years, such as the potentially domoic acid producers Pseudo-nitzschia cf. galaxiae and P seudo-nitzschia cf. multistriata, identified for the first time in these waters. The presence of HABs represents a threat for human health and aquaculture. Urgent initiatives are needed to improve the communication with authorities responsible for environmental protection, economic development, and public health for a sustainable mussel culture in the Mar Piccolo.

  17. 20 CFR 404.384 - Reductions, suspensions, and nonpayments of special age 72 payments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... special age 72 payments. 404.384 Section 404.384 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance Benefits; Period of Disability Special Payments at Age 72 § 404.384...

  18. 20 CFR 404.384 - Reductions, suspensions, and nonpayments of special age 72 payments.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... special age 72 payments. 404.384 Section 404.384 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance Benefits; Period of Disability Special Payments at Age 72 § 404.384...

  19. 20 CFR 404.384 - Reductions, suspensions, and nonpayments of special age 72 payments.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... special age 72 payments. 404.384 Section 404.384 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance Benefits; Period of Disability Special Payments at Age 72 § 404.384...

  20. 20 CFR 404.384 - Reductions, suspensions, and nonpayments of special age 72 payments.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... special age 72 payments. 404.384 Section 404.384 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance Benefits; Period of Disability Special Payments at Age 72 § 404.384...

  1. 20 CFR 404.384 - Reductions, suspensions, and nonpayments of special age 72 payments.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... special age 72 payments. 404.384 Section 404.384 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance Benefits; Period of Disability Special Payments at Age 72 § 404.384...

  2. Inference, simulation, modeling, and analysis of complex networks, with special emphasis on complex networks in systems biology

    NASA Astrophysics Data System (ADS)

    Christensen, Claire Petra

    's own publications have contributed network inference, simulation, modeling, and analysis methods to the much larger body of work in systems biology, and indeed, in network science. The aim of this thesis is therefore twofold: to present this original work in the historical context of network science, but also to provide sufficient review and reference regarding complex systems (with an emphasis on complex networks in systems biology) and tools and techniques for their inference, simulation, analysis, and modeling, such that the reader will be comfortable in seeking out further information on the subject. The review-like Chapters 1, 2, and 4 are intended to convey the co-evolution of network science and the slow but noticeable breakdown of boundaries between disciplines in academia as research and comparison of diverse systems has brought to light the shared properties of these systems. It is the author's hope that theses chapters impart some sense of the remarkable and rapid progress in complex systems research that has led to this unprecedented academic synergy. Chapters 3 and 5 detail the author's original work in the context of complex systems research. Chapter 3 presents the methods and results of a two-stage modeling process that generates candidate gene-regulatory networks of the bacterium B.subtilis from experimentally obtained, yet mathematically underdetermined microchip array data. These networks are then analyzed from a graph theoretical perspective, and their biological viability is critiqued by comparing the networks' graph theoretical properties to those of other biological systems. The results of topological perturbation analyses revealing commonalities in behavior at multiple levels of complexity are also presented, and are shown to be an invaluable means by which to ascertain the level of complexity to which the network inference process is robust to noise. Chapter 5 outlines a learning algorithm for the development of a realistic, evolving social

  3. Analysis and mitigation of remote geohazards in high mountain areas of Tajikistan with special emphasis on glacial lake outburst floods

    NASA Astrophysics Data System (ADS)

    Schneider, Jean F.; Mergili, Martin; Schneider, Demian

    2010-05-01

    downstream. Most of these lakes are dammed by moraines containing some ice. A significant example for a lake dammed by a rock glacier is located in the Central Pamir. Currently, the dam appears stable, but further melting of the ice could lead to a progressive failure. In the highest portions of the Pamir, glacial retreat and the development of glacial lakes has not yet reached the stage as observed farther South. However, future retreat, but also surging of glaciers in the area may result in new lakes. The Alai Mountains in North-western Tajikistan have experienced comparable processes in the past. However, damming of lakes by rainfall-triggered landslides has still been reported repeatedly. Two major tectonic faults run through the territory of Tajikistan, allowing earthquake magnitudes of 7.5 and more. Whilst dams may be weakened by earthquakes, or flood waves may be generated by rock falls into the lakes, several lakes dammed by earthquake-triggered landslides do exist or have broken out. It is certain that new lakes of this type will develop in the future, but the size and exact location are hard to predict. Targeted and well-planned mitigation measures are required to prevent that future remote geohazard events will evolve into disasters, or at least to reduce the magnitude of the disaster. This requires conversion of the knowledge gained during the assessment into strategies and procedures for reducing the risk, e.g. promoting the awareness and preparedness, initiating monitoring and technical measures, and installing emergency information systems. In order to enable the realization of all these activities, much emphasis was put on capacity-building of the local actors: all the relevant agencies, scientists, and stakeholders were involved already in the hazard assessment, and specific training workshops were carried out.

  4. Energy-related metabolites during and after induced myocardial infarction with special emphasis on the reperfusion injury after extracorporeal circulation.

    PubMed

    Zemgulis, V; Ronquist, G; Bjerner, T; Henze, A; Waldenström, A; Thelin, S; Wikström, G

    2001-02-01

    In the clinical setting great efforts have been made with contradictory results to operate upon acutely myocardial ischaemic patients. The reasons for the absence of clear-cut results are not well understood nor are they scientifically explored. To resolve this problem further, we attempted to design an experimental in vivo model to mimic acute myocardial ischaemia followed by extracorporeal circulation (ECC) and reperfusion. One of the main targets of our protocol was monitoring of myocardial energy metabolism by microdialysis (MCD) during the periods of coronary occlusion (60 min), hypothermic (30 degrees C) ECC and cardioplegia (45 min), followed by reperfusion with (30 min) and without (60 min) ECC. In eight anaesthetized, open-chest pigs, myocardial lactate, pyruvate, adenosine, taurine, inosine, hypoxanthine and guanosine were sampled with MCD in both ischaemic and non-ischaemic areas. Myocardial area at risk and infarct size were quantified with the modified topographical evaluation methods. The principal finding with this experimental setup was a biphasic release pattern of lactate, adenosine, taurine, inosine, hypoxanthine and guanosine from ischaemic myocardium. Lactate levels were equally high in reperfused ischaemic and non-ischaemic myocardial tissue. Pyruvate demonstrated consistently higher values in non-ischaemic myocardium throughout the experiment. A pattern was discernible, lactate being a marker of compromised cell energy metabolism, and taurine being a marker of disturbed cell integrity. Of special interest was the increased level of pyruvate in microdialysates of non-ischaemic myocardium as compared with its ischaemic counterpart. In conclusion, we found disturbances in energy metabolism and cell integrity not only in ischaemic but also in non-ischaemic tissue during reperfusion implying that non-ischaemic myocardium demonstrated an unexpected accumulation of lactate and pyruvate. These new findings could at least partly be explicatory to the

  5. Inference, simulation, modeling, and analysis of complex networks, with special emphasis on complex networks in systems biology

    NASA Astrophysics Data System (ADS)

    Christensen, Claire Petra

    's own publications have contributed network inference, simulation, modeling, and analysis methods to the much larger body of work in systems biology, and indeed, in network science. The aim of this thesis is therefore twofold: to present this original work in the historical context of network science, but also to provide sufficient review and reference regarding complex systems (with an emphasis on complex networks in systems biology) and tools and techniques for their inference, simulation, analysis, and modeling, such that the reader will be comfortable in seeking out further information on the subject. The review-like Chapters 1, 2, and 4 are intended to convey the co-evolution of network science and the slow but noticeable breakdown of boundaries between disciplines in academia as research and comparison of diverse systems has brought to light the shared properties of these systems. It is the author's hope that theses chapters impart some sense of the remarkable and rapid progress in complex systems research that has led to this unprecedented academic synergy. Chapters 3 and 5 detail the author's original work in the context of complex systems research. Chapter 3 presents the methods and results of a two-stage modeling process that generates candidate gene-regulatory networks of the bacterium B.subtilis from experimentally obtained, yet mathematically underdetermined microchip array data. These networks are then analyzed from a graph theoretical perspective, and their biological viability is critiqued by comparing the networks' graph theoretical properties to those of other biological systems. The results of topological perturbation analyses revealing commonalities in behavior at multiple levels of complexity are also presented, and are shown to be an invaluable means by which to ascertain the level of complexity to which the network inference process is robust to noise. Chapter 5 outlines a learning algorithm for the development of a realistic, evolving social

  6. Heavy metal concentrations in soils as determined by laser-induced breakdown spectroscopy (LIBS), with special emphasis on chromium

    SciTech Connect

    Senesi, G.S.; De Giacomo, A.; Zaccone, C.

    2009-05-15

    Soil is unanimously considered as one of the most important sink of heavy metals released by human activities. Heavy metal analysis of natural and polluted soils is generally conducted by the use of atomic absorption spectroscopy (AAS) or inductively coupled plasma optical emission spectroscopy (ICP-OES) on adequately obtained soil extracts. Although in recent years the emergent technique of laser-induced breakdown spectroscopy (LIBS) has been applied widely and with increasing success for the qualitative and quantitative analyses of a number of heavy metals in soil matrices with relevant simplification of the conventional methodologies, the technique still requires further confirmation before it can be applied fully successfully in soil analyses. The main objective of this work was to demonstrate that new developments in LIBS technique are able to provide reliable qualitative and quantitative analytical evaluation of several heavy metals in soils, with special focus on the element chromium (Cr), and with reference to the concentrations measured by conventional ICP spectroscopy. The preliminary qualitative LIBS analysis of five soil samples and one sewage sludge sample has allowed the detection of a number of elements including Al, Ca, Cr, Cu, Fe, Mg, Mn, Pb, Si, Ti, V and Zn. Of these, a quantitative analysis was also possible for the elements Cr, Cu, Pb, V and Zn based on the obtained linearity of the calibration curves constructed for each heavy metal, i.e., the proportionality between the intensity of the LIBS emission peaks and the concentration of each heavy metal in the sample measured by ICP. In particular, a triplet of emission lines for Cr could be used for its quantitative measurement. The consistency of experiments made on various samples was supported by the same characteristics of the laser-induced plasma (LIP), i.e., the typical linear distribution confirming the existence of local thermodynamic equilibrium (LTE) condition, and similar excitation

  7. Quantitative estimates of dietary intake with special emphasis on snacking pattern and nutritional status of free living adults in urban slums of Delhi: impact of nutrition transition

    PubMed Central

    Singh, Archna; Gupta, Vidhu; Ghosh, Arpita; Lock, Karen; Ghosh-Jerath, Suparna

    2016-01-01

    Background The nutritional landscape of India is experiencing the fallout of urbanization and globalization. The changes are manifest in dietary patterns as well as health outcomes. The study aimed at assessing household dietary intake pattern with special emphasis on snacking pattern, anthropometric and lipid profiles in low socio-economic status households in an urban slum of Delhi. Methods Community based cross-sectional study in 260 households of a purposively selected urban slum in North-East district of Delhi, India. Family dietary surveys including consumption pattern of commercial food products rich in Partially Hydrogenated Vegetable Oils (PHVOs), 24 h dietary recall and assessment of dietary diversity using Household Diet Diversity Scores (HDDS) were done. Assessment of nutritional status using anthropometric and lipid profile on a subsample (n =130) were also conducted. Results Median energy and fat intake were adequate. Micronutrient intake was found to be inadequate for vitamin A, riboflavin, calcium and folate. PHVO usage was low (<20 % households). Milk (39 %), green leafy vegetables (25 %) and fruits (25 %) intake were below recommendations. Mean HDDS was 7.87. Prevalence of overweight/obesity was high (66.7 %). Lipid profile showed mean HDL-C levels lower than recommendations for females. Conclusion Community based awareness programs for prevention of non-communicable diseases should incorporate healthy diet and lifestyle practices with emphasis on quantity and quality of nutrient intake. This must be considered as an integral part of chronic disease prevention strategy for underprivileged communities in urban India. PMID:26918196

  8. Modifications to an interactive model of the human body during exercise: With special emphasis on thermoregulation. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Scherb, Megan Kay

    1993-01-01

    Since 1988 an interactive computer model of the human body during exercise has been under development by a number of undergraduate students in the Department of Chemical Engineering at Iowa State University. The program, written under the direction of Dr. Richard C. Seagrave, uses physical characteristics of the user, environmental conditions and activity information to predict the onset of hypothermia, hyperthermia, dehydration, or exhaustion for various levels and durations of a specified exercise. The program however, was severely limited in predicting the onset of dehydration due to the lack of sophistication with which the program predicts sweat rate and its relationship to sensible water loss, degree of acclimatization, and level of physical training. Additionally, it was not known whether sweat rate also depended on age and gender. For these reasons, the goal of this creative component was to modify the program in the above mentioned areas by applying known information and empirical relationships from literature. Furthermore, a secondary goal was to improve the consistency with which the program was written by modifying user input statements and improving the efficiency and logic of the program calculations.

  9. Gross anatomical, CT and MRI analyses of the buccal fat pad with special emphasis on volumetric variations.

    PubMed

    Loukas, Marios; Kapos, Theodoros; Louis, Robert G; Wartman, Christopher; Jones, Ashley; Hallner, Barry

    2006-06-01

    The use of the buccal fat pad (BFP) has increased in popularity in recent years because of its reliability, ease of harvest, and low complication rate during oral and maxillofacial procedures. The aim of this study was to evaluate the volumetric variations of the BFP with a CT and MRI, as well as the thickness, weight and volume with conventional methods. We have examined the BFP from 80 formalin fixed adult cadavers (mean age 59) derived from both males (45) and females (35). In addition, we also examined 20 cadaveric BFPs using MR and CT imaging. Digital image analysis software was used to measure the volumetric distribution and to characterize the morphology of BFP. The BFP can be divided into three lobes (anterior, intermediate, and posterior) and has four extensions (buccal, pterygoid, pterygopalatine, and temporal). The BFP is fixed by six ligaments, to the maxilla, posterior zygoma, inner and outer rim of infraorbital fissure, temporalis tendon, and buccinator membrane. The mean volume in males was 10.2 ml and ranged 7.8-11.2 ml, while in females the mean volume was 8.9 ml and ranged 7.2-10.8 ml. Additionally, the mean thickness was 6 mm, with a mean weight of 9.7 g. These facts may be important when considering the use of the BFP in reconstruction, particularly whether the correct volume has been removed from each side in aesthetic, oral, or maxillofacial procedures. PMID:16528468

  10. Developmental Screening and Assessment Instruments with an Emphasis on Social and Emotional Development for Young Children Ages Birth through Five

    ERIC Educational Resources Information Center

    Ringwalt, Sharon, Comp.

    2008-01-01

    In recent years, there has been a growing emphasis on the mental health and social and behavioral developmental needs of very young children. In response, state administrators and local providers of early intervention and preschool programs have worked to strengthen their screening and assessment of children's social and emotional development. The…

  11. 78 FR 21960 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... Committee: National Institute on Aging Special Emphasis Panel; Presenilins and Alzheimer's Disease. Date..., PARSADANIANA@NIA.NIH.GOV . Name of Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's... Special Emphasis Panel; Alzheimer's Disease Prevention. Date: July 11, 2013. Time: 12 p.m. to 1...

  12. The fine structure of the midgut epithelium in a centipede, Scolopendra cingulata (Chilopoda, Scolopendridae), with the special emphasis on epithelial regeneration.

    PubMed

    Chajec, Lukasz; Sonakowska, Lidia; Rost-Roszkowska, Magdalena M

    2014-01-01

    Scolopendra cingulata has a tube-shaped digestive system that is divided into three distinct regions: fore-, mid- and hindgut. The midgut is lined with a pseudostratified columnar epithelium which is composed of digestive, secretory and regenerative cells. Hemocytes also appear between the digestive cells of the midgut epithelium. The ultrastructure of three types of epithelial cells and hemocytes of the midgut has been described with the special emphasis on the role of regenerative cells in the protection of midgut epithelium. The process of midgut epithelium regeneration proceeds due to the ability of regenerative cells to proliferate and differentiate according to a circadian rhythm. The regenerative cells serve as unipotent stem cells that divide in an asymmetric manner. Additionally, two types of hemocytes have been distinguished among midgut epithelial cells. They enter the midgut epithelium from the body cavity. Because of the fact that numerous microorganisms occur in the cytoplasm of midgut epithelial cells, we discuss the role of hemocytes in elimination of pathogens from the midgut epithelium. The studies were conducted with the use of transmission electron microscope and immunofluorescent methods.

  13. Effect of ice storage on the functional properties of proteins from a few species of fresh water fish (Indian major carps) with special emphasis on gel forming ability.

    PubMed

    Mehta, Naresh Kumar; Elavarasan, K; Reddy, A Manjunatha; Shamasundar, B A

    2014-04-01

    In the present study the effect of ice storage on physico-chemical and functional properties of proteins from Indian major carps with special emphasis on gel forming ability have been assessed for a period of 22 days. The solubility profile of proteins in high ionic strength buffer and calcium adenosine triphosphatase (ATPase) enzyme activity reduced significantly (p < 0.05), while that of total volatile base nitrogen (TVB-N) increased significantly (p < 0.05) at the end of 22 days of ice storage. The major protein fraction showed association-dissociation-denaturation phenomenon during ice storage as revealed by gel filtration profile and viscosity measurements. The gel forming ability of three fish species both in fresh and during different periods of ice storage was assessed by measuring the gel strength of heat induced gel. Among the three species the gel strength of the gel obtained from Catla catla and Cirrhinus mrigala was higher (586 and 561 g.cm) than the gel obtained from Labeo rohita (395 g.cm) in fresh condition. The gel forming ability of three species was significantly affected (p < 0.05) during ice storage. The TVB-N values of fish meat as a function of ice storage was within the prescribed limit up to 17 days of the ice storage.

  14. Effect of ice storage on the functional properties of proteins from a few species of fresh water fish (Indian major carps) with special emphasis on gel forming ability.

    PubMed

    Mehta, Naresh Kumar; Elavarasan, K; Reddy, A Manjunatha; Shamasundar, B A

    2014-04-01

    In the present study the effect of ice storage on physico-chemical and functional properties of proteins from Indian major carps with special emphasis on gel forming ability have been assessed for a period of 22 days. The solubility profile of proteins in high ionic strength buffer and calcium adenosine triphosphatase (ATPase) enzyme activity reduced significantly (p < 0.05), while that of total volatile base nitrogen (TVB-N) increased significantly (p < 0.05) at the end of 22 days of ice storage. The major protein fraction showed association-dissociation-denaturation phenomenon during ice storage as revealed by gel filtration profile and viscosity measurements. The gel forming ability of three fish species both in fresh and during different periods of ice storage was assessed by measuring the gel strength of heat induced gel. Among the three species the gel strength of the gel obtained from Catla catla and Cirrhinus mrigala was higher (586 and 561 g.cm) than the gel obtained from Labeo rohita (395 g.cm) in fresh condition. The gel forming ability of three species was significantly affected (p < 0.05) during ice storage. The TVB-N values of fish meat as a function of ice storage was within the prescribed limit up to 17 days of the ice storage. PMID:24741158

  15. The fine structure of the midgut epithelium in a centipede, Scolopendra cingulata (Chilopoda, Scolopendridae), with the special emphasis on epithelial regeneration.

    PubMed

    Chajec, Lukasz; Sonakowska, Lidia; Rost-Roszkowska, Magdalena M

    2014-01-01

    Scolopendra cingulata has a tube-shaped digestive system that is divided into three distinct regions: fore-, mid- and hindgut. The midgut is lined with a pseudostratified columnar epithelium which is composed of digestive, secretory and regenerative cells. Hemocytes also appear between the digestive cells of the midgut epithelium. The ultrastructure of three types of epithelial cells and hemocytes of the midgut has been described with the special emphasis on the role of regenerative cells in the protection of midgut epithelium. The process of midgut epithelium regeneration proceeds due to the ability of regenerative cells to proliferate and differentiate according to a circadian rhythm. The regenerative cells serve as unipotent stem cells that divide in an asymmetric manner. Additionally, two types of hemocytes have been distinguished among midgut epithelial cells. They enter the midgut epithelium from the body cavity. Because of the fact that numerous microorganisms occur in the cytoplasm of midgut epithelial cells, we discuss the role of hemocytes in elimination of pathogens from the midgut epithelium. The studies were conducted with the use of transmission electron microscope and immunofluorescent methods. PMID:23831526

  16. Leptin and aging: Review and questions with particular emphasis on its role in the central regulation of energy balance.

    PubMed

    Balaskó, Márta; Soós, Szilvia; Székely, Miklós; Pétervári, Erika

    2014-11-01

    Leptin is produced mainly in the white adipose tissue and emerged as one of the key catabolic regulators of food intake and energy expenditure. During the course of aging characteristic alterations in body weight and body composition in humans and mammals, i.e. middle-aged obesity and aging anorexia and cachexia, suggest age-related regulatory changes in energy balance in the background. Aging has been associated with increased fat mass, central and peripheral leptin resistance as indicated by its failure to reduce food intake, to increase metabolic rate and thereby to induce weight loss. Leptin resistance is a common feature of aging and obesity (even in the young). The question arises whether aging or fat accumulation plays the primary role in the development of this resistance. The review focuses mainly on mechanisms and development of central leptin resistance. Age-related decline primarily affects the hypermetabolic component of central catabolic leptin actions, while the anorexigenic component is even growing stronger in the late phase of aging. Obesity enhances resistance to leptin at any age, particularly in old rats, calorie-restriction, on the other hand, increases responsiveness to leptin, especially in the oldest age-group. Thus, without obesity, leptin sensitivity appears not to decrease but to increase by old age. Interactions with other substances (e.g. insulin, cholecystokinin, endogenous cannabinoids) and life-style factors (e.g. exercise) in these age-related changes need to be investigated. PMID:25218974

  17. Special Report: Vocational Training in the High-Tech Age.

    ERIC Educational Resources Information Center

    Mansnerus, Laura; And Others

    1994-01-01

    "New Pressures on Vocational Education" (Mansnerus) describes new forms (tech prep, career academies, apprenticeship, school enterprises); "Biotechnology Goes to High School" (Quinn) describes Berkeley High's Biotech Academy created by industry; and "Votech That Works" (Holusha) stresses the importance of specialized training for non-college-bound…

  18. The Special Value of Children's Age-Mixed Play

    ERIC Educational Resources Information Center

    Gray, Peter

    2011-01-01

    From an evolutionary perspective, the normal social play of children involves kids of various ages. Our human and great-ape ancestors most likely lived in small groups with low birth rates, which made play with others of nearly the same age rare. Consequently, the evolutionary functions of children's social play are best understood by examining…

  19. 20 CFR 404.382 - When special age 72 payments begin and end.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false When special age 72 payments begin and end. 404.382 Section 404.382 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance...

  20. 20 CFR 404.381 - Who is entitled to special age 72 payments?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Who is entitled to special age 72 payments? 404.381 Section 404.381 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance...

  1. 20 CFR 404.382 - When special age 72 payments begin and end.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false When special age 72 payments begin and end. 404.382 Section 404.382 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance...

  2. 20 CFR 404.381 - Who is entitled to special age 72 payments?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Who is entitled to special age 72 payments? 404.381 Section 404.381 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance...

  3. Graduates' Perspectives on a National Specialized Program in Social Work and Aging

    ERIC Educational Resources Information Center

    Greenfield, Emily A.; Shpiegel, Svetlana

    2012-01-01

    Recognizing the growing need for social workers with specialized training in aging, the Hartford Partnership Program for Aging Education (HPPAE) has developed as a nationwide initiative to enhance aging education for master's-level social work students. This study presents a content analysis of answers to 2 open-ended questions in a national…

  4. 20 CFR 404.382 - When special age 72 payments begin and end.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false When special age 72 payments begin and end. 404.382 Section 404.382 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance...

  5. 20 CFR 404.381 - Who is entitled to special age 72 payments?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Who is entitled to special age 72 payments? 404.381 Section 404.381 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance...

  6. 20 CFR 404.382 - When special age 72 payments begin and end.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false When special age 72 payments begin and end. 404.382 Section 404.382 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance...

  7. 20 CFR 404.381 - Who is entitled to special age 72 payments?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Who is entitled to special age 72 payments? 404.381 Section 404.381 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance...

  8. 20 CFR 404.381 - Who is entitled to special age 72 payments?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Who is entitled to special age 72 payments? 404.381 Section 404.381 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance...

  9. 20 CFR 404.382 - When special age 72 payments begin and end.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false When special age 72 payments begin and end. 404.382 Section 404.382 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance...

  10. The implications of anatomical and functional changes of the aging kidney: with an emphasis on the glomeruli.

    PubMed

    Glassock, Richard J; Rule, Andrew D

    2012-08-01

    Aging is both a natural and inevitable biological process. With advancing age, the kidneys undergo anatomical and physiological changes that are not only the consequences of normal organ senescence but also of specific diseases (such as atherosclerosis or diabetes) that occur with greater frequency in older individuals. Disentangling these two processes, one pathologic and the other physiologic, is difficult. In this review we concentrate on the glomerular structural and functional alterations that accompany natural aging. We also analyze how these changes affect the identification of individuals of advancing age as having chronic kidney disease (CKD) and how these changes can influence prognosis for adverse outcomes, including all-cause mortality, end-stage renal disease, cardiovascular events and mortality, and acute kidney injury. This review describes important shortcomings and deficiencies with our current approach and understanding of CKD in the older and elderly adult.

  11. Competitive bidding and voucher payments for implementing the new federalism with special emphasis on programs for the aging.

    PubMed

    Hogan, A J

    1983-01-01

    Principles from the economics of decentralization are applied to the planning and budgeting of social services for the elderly. The standard model of corporate decentralized planning and budgeting is extended to allow different levels of government to pursue qualitatively different goals. A safety-net voucher plan is also proposed to protect the most vunerable population from possible termination of services due to poorly formulated local plans. Such a decentralized planning and budgeting system would make Federal and State influence on local plans proportional to their contribution to total expenditures. PMID:10260472

  12. Functional Curriculum for Elementary, Middle, and Secondary Age Students with Special Needs. Second Edition

    ERIC Educational Resources Information Center

    Wehman, Paul; Kregel, John

    2004-01-01

    The second edition of Functional Curriculum for Elementary, Middle, and Secondary Age Students with Special Needs has an expanded framework for a functional and longitudinal curriculum for children and adolescents with disabilities and other special needs. These is a stronger demand than ever to provide a curriculum with everyday usefulness and…

  13. Postmortem Aging of Beef with a Special Reference to the Dry Aging

    PubMed Central

    Khan, Muhammad I.; Jung, Samooel; Nam, Ki Chang; Jo, Cheorun

    2016-01-01

    Animal muscles are stored for specific period (aging) at refrigerated temperatures, during and after which the living muscles start to convert into meat and thus, attain certain superior properties in the final product. Proteolysis, lipolysis, and oxidation are the major biochemical processes involved during the postmortem aging of meat that affect the tenderness, juiciness, and flavor, as well as sometimes may introduce certain undesirable traits. This review analyzes the role of pre- and post-mortem factors that are important for aging and their effect on the chemical and physical changes in the “dry- and wet-aged meat.” Thus, if the meat processing manufacturers optimize the effects of aging for specific muscles, the palatability, color, and the shelf life of the aged meat products could be significantly enhanced. PMID:27194923

  14. Postmortem Aging of Beef with a Special Reference to the Dry Aging.

    PubMed

    Khan, Muhammad I; Jung, Samooel; Nam, Ki Chang; Jo, Cheorun

    2016-01-01

    Animal muscles are stored for specific period (aging) at refrigerated temperatures, during and after which the living muscles start to convert into meat and thus, attain certain superior properties in the final product. Proteolysis, lipolysis, and oxidation are the major biochemical processes involved during the postmortem aging of meat that affect the tenderness, juiciness, and flavor, as well as sometimes may introduce certain undesirable traits. This review analyzes the role of pre- and post-mortem factors that are important for aging and their effect on the chemical and physical changes in the "dry- and wet-aged meat." Thus, if the meat processing manufacturers optimize the effects of aging for specific muscles, the palatability, color, and the shelf life of the aged meat products could be significantly enhanced. PMID:27194923

  15. Postmortem Aging of Beef with a Special Reference to the Dry Aging.

    PubMed

    Khan, Muhammad I; Jung, Samooel; Nam, Ki Chang; Jo, Cheorun

    2016-01-01

    Animal muscles are stored for specific period (aging) at refrigerated temperatures, during and after which the living muscles start to convert into meat and thus, attain certain superior properties in the final product. Proteolysis, lipolysis, and oxidation are the major biochemical processes involved during the postmortem aging of meat that affect the tenderness, juiciness, and flavor, as well as sometimes may introduce certain undesirable traits. This review analyzes the role of pre- and post-mortem factors that are important for aging and their effect on the chemical and physical changes in the "dry- and wet-aged meat." Thus, if the meat processing manufacturers optimize the effects of aging for specific muscles, the palatability, color, and the shelf life of the aged meat products could be significantly enhanced.

  16. 77 FR 40368 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel Age, Gene/Environment Susceptibility... evaluate contract proposals. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin...

  17. Specialized Science

    PubMed Central

    Fang, Ferric C.

    2014-01-01

    As the body of scientific knowledge in a discipline increases, there is pressure for specialization. Fields spawn subfields that then become entities in themselves that promote further specialization. The process by which scientists join specialized groups has remarkable similarities to the guild system of the middle ages. The advantages of specialization of science include efficiency, the establishment of normative standards, and the potential for greater rigor in experimental research. However, specialization also carries risks of monopoly, monotony, and isolation. The current tendency to judge scientific work by the impact factor of the journal in which it is published may have roots in overspecialization, as scientists are less able to critically evaluate work outside their field than before. Scientists in particular define themselves through group identity and adopt practices that conform to the expectations and dynamics of such groups. As part of our continuing analysis of issues confronting contemporary science, we analyze the emergence and consequences of specialization in science, with a particular emphasis on microbiology, a field highly vulnerable to balkanization along microbial phylogenetic boundaries, and suggest that specialization carries significant costs. We propose measures to mitigate the detrimental effects of scientific specialism. PMID:24421049

  18. Specialized science.

    PubMed

    Casadevall, Arturo; Fang, Ferric C

    2014-04-01

    As the body of scientific knowledge in a discipline increases, there is pressure for specialization. Fields spawn subfields that then become entities in themselves that promote further specialization. The process by which scientists join specialized groups has remarkable similarities to the guild system of the middle ages. The advantages of specialization of science include efficiency, the establishment of normative standards, and the potential for greater rigor in experimental research. However, specialization also carries risks of monopoly, monotony, and isolation. The current tendency to judge scientific work by the impact factor of the journal in which it is published may have roots in overspecialization, as scientists are less able to critically evaluate work outside their field than before. Scientists in particular define themselves through group identity and adopt practices that conform to the expectations and dynamics of such groups. As part of our continuing analysis of issues confronting contemporary science, we analyze the emergence and consequences of specialization in science, with a particular emphasis on microbiology, a field highly vulnerable to balkanization along microbial phylogenetic boundaries, and suggest that specialization carries significant costs. We propose measures to mitigate the detrimental effects of scientific specialism. PMID:24421049

  19. Cluster Headache: Special Considerations for Treatment of Female Patients of Reproductive Age and Pediatric Patients.

    PubMed

    VanderPluym, Juliana

    2016-01-01

    Cluster headache is a rare disorder that is more common in adult male patients. It has a unique phenotype of unilateral, severe, to very severe headaches lasting 15 to 180 min with ipsilateral autonomic symptoms. Time to correct diagnosis can be protracted. A number of treatment options exist for the standard cluster headache patient, but special considerations must be made for female patients of reproductive age and pediatric patients. The objective of this article is to explore the current literature pertaining to special considerations in cluster headache management, including treatment of pregnant or breastfeeding patients and pediatric patients. PMID:26711274

  20. Genetic characterization and phylogenetic analysis of skunk-associated rabies viruses in North America with special emphasis on the central plains.

    PubMed

    Davis, Rolan; Nadin-Davis, Susan A; Moore, Michael; Hanlon, Cathleen

    2013-06-01

    Across North America the skunk acts as a reservoir for several rabies virus variants. Some of these variants are geographically restricted in range as is the case for the California skunk variant and two distinct variants present in Mexico. In contrast the North Central and South Central skunk rabies viruses are dispersed in overlapping ranges over large areas of the Midwestern region of the United States with the former extending into southern parts of the Canadian prairies. Despite this extensive range, there has been only very limited molecular characterization of these two viral variants. This study has examined the genetic diversity of the rabies viruses associated with North American skunks, with particular emphasis on the South Central skunk variant which was found to comprise three distinct geographically restricted groups of viruses that could in some cases be further sub-divided. The phylogenetic relationships of these groups and sub-groups allowed us to infer the likely direction of spread of these variants in some instances. Patterns of amino acid replacement of North American skunk-associated rabies viruses for both the nucleoprotein and glycoprotein products are also examined. These patterns reflect the virus phylogeny but no amino acid residues associated specifically with the skunk host were identified. PMID:23524137

  1. Genetic characterization and phylogenetic analysis of skunk-associated rabies viruses in North America with special emphasis on the central plains.

    PubMed

    Davis, Rolan; Nadin-Davis, Susan A; Moore, Michael; Hanlon, Cathleen

    2013-06-01

    Across North America the skunk acts as a reservoir for several rabies virus variants. Some of these variants are geographically restricted in range as is the case for the California skunk variant and two distinct variants present in Mexico. In contrast the North Central and South Central skunk rabies viruses are dispersed in overlapping ranges over large areas of the Midwestern region of the United States with the former extending into southern parts of the Canadian prairies. Despite this extensive range, there has been only very limited molecular characterization of these two viral variants. This study has examined the genetic diversity of the rabies viruses associated with North American skunks, with particular emphasis on the South Central skunk variant which was found to comprise three distinct geographically restricted groups of viruses that could in some cases be further sub-divided. The phylogenetic relationships of these groups and sub-groups allowed us to infer the likely direction of spread of these variants in some instances. Patterns of amino acid replacement of North American skunk-associated rabies viruses for both the nucleoprotein and glycoprotein products are also examined. These patterns reflect the virus phylogeny but no amino acid residues associated specifically with the skunk host were identified.

  2. Distribution of immunoreactive glutamine synthetase in the adult human and mouse brain. Qualitative and quantitative observations with special emphasis on extra-astroglial protein localization.

    PubMed

    Bernstein, Hans-Gert; Bannier, Jana; Meyer-Lotz, Gabriela; Steiner, Johann; Keilhoff, Gerburg; Dobrowolny, Henrik; Walter, Martin; Bogerts, Bernhard

    2014-11-01

    Glutamine synthetase catalyzes the ATP-dependent condensation of ammonia and glutamate to form glutamine, thus playing a pivotal role in glutamate and glutamine homoeostasis. Despite a plethora of studies on this enzyme, knowledge about the regional and cellular distribution of this enzyme in human brain is still fragmentary. Therefore, we mapped fourteen post-mortem brains of psychically healthy individuals for the distribution of the glutamine synthetase immunoreactive protein. It was found that glutamine synthetase immunoreactivity is expressed in multiple gray and white matter astrocytes, but also in oligodendrocytes, ependymal cells and certain neurons. Since a possible extra-astrocytic expression of glutamine synthetase is highly controversial, we paid special attention to its appearance in oligodendrocytes and neurons. By double immunolabeling of mouse brain slices and cultured mouse brain cells for glutamine synthetase and cell-type-specific markers we provide evidence that besides astrocytes subpopulations of oligodendrocytes, microglial cells and neurons express glutamine synthetase. Moreover, we show that glutamine synthetase-immunopositive neurons are not randomly distributed throughout human and mouse brain, but represent a subpopulation of nitrergic (i.e. neuronal nitric oxide synthase expressing) neurons. Possible functional implications of an extra-astrocytic localization of glutamine synthetase are discussed.

  3. 77 FR 2737 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Development and Maintenance of a... and evaluate contract proposals. Place: National Institute on Aging, Gateway Building, 7201...

  4. 75 FR 4829 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-29

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Development and Maintenance of a... contract proposals. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Ave, Suite...

  5. Hereditary angioedema: special consideration in children, women of childbearing age, and the elderly.

    PubMed

    Kuhlen, James L; Banerji, Aleena

    2015-01-01

    This review on hereditary angioedema (HAE) focused on special topics regarding HAE in children, women of childbearing age, and the elderly. HAE is a rare autosomal dominant bradykinin-mediated disorder characterized by recurrent attacks of subcutaneous or submucosal swelling that usually affects the face, upper airway, extremities, gastrointestinal tract, or genitalia. These recurrent attacks cause significant morbidity and can be life threatening, especially when the swelling affects the airway. Our objective was to summarize the published data available on the disease epidemiology, pathophysiology, clinical presentation, on demand and prophylactic therapy, and focus on management considerations for these special patient populations. Unique aspects of HAE in women with regard to contraception, hormone replacement therapy, pregnancy, lactation, and menopause were also reviewed.

  6. [Impact of commuting on partnership and family life. A literature review of the current state of research with special emphasis on commuter marriages].

    PubMed

    Häfner, Steffen

    2011-01-01

    Because of modern working conditions, for many people commuting has increasingly become a necessity with many consequences for their health as well as for their family life and partnership. To date, little research has been done concerning the impact of this modern lifestyle on partnership and family life, particularly on dual-career couples and long-distance commuters. The results of a literature review are presented based on age, sex, family cycle and consequences for children; research questions are formulated. Sex-specific differences seem to be especially important, confirming the "household responsibility hypothesis." The commuter marriage as a new lifestyle seems to have become a coping mechanism for the increasing necessity in our society to commute.

  7. Modelling multi-species interactions in the Barents Sea ecosystem with special emphasis on minke whales and their interactions with cod, herring and capelin

    NASA Astrophysics Data System (ADS)

    Lindstrøm, Ulf; Smout, Sophie; Howell, Daniel; Bogstad, Bjarte

    2009-10-01

    The Barents Sea ecosystem, one of the most productive and commercially important ecosystems in the world, has experienced major fluctuations in species abundance the past five decades. Likely causes are natural variability, climate change, overfishing and predator-prey interactions. In this study, we use an age-length structured multi-species model (Gadget, Globally applicable Area-Disaggregated General Ecosystem Toolbox) to analyse the historic population dynamics of major fish and marine mammal species in the Barents Sea. The model was used to examine possible effects of a number of plausible biological and fisheries scenarios. The results suggest that changes in cod mortality from fishing or cod cannibalism levels have the largest effect on the ecosystem, while changes to the capelin fishery have had only minor effects. Alternate whale migration scenarios had only a moderate impact on the modelled ecosystem. Indirect effects are seen to be important, with cod fishing pressure, cod cannibalism and whale predation on cod having an indirect impact on capelin, emphasising the importance of multi-species modelling in understanding and managing ecosystems. Models such as the one presented here provide one step towards an ecosystem-based approach to fisheries management.

  8. Oocyte maturation. Basic and clinical aspects of in vitro maturation (IVM) with special emphasis of the role of FF-MAS.

    PubMed

    Grøndahl, Christian

    2008-02-01

    In Vitro maturation (IVM) of human oocytes is an emerging infertility treatment with great promise. To be successful this future assisted reproductive technology must entail both nuclear and cytoplasmic maturation of the oocytes and give rise to human embryos that have the same developmental potential as embryos resulting from the golden standard of human IVF. The aspiration of immature oocytes from small to medium size antral follicles followed by their maturation In Vitro present an attractive alternative to the hormonal stimulation of patients in In Vitro fertilization (IVF) treatment, since administration of exogenous hormones is a costly treatment and may cause severe health problems. Of the long list of side effect and health concern ovarian hyper-stimulation syndrome (OHSS) is by far the most severe although long term effect on cancer prevalence is another concern. Another potential group of patients that could benefit from future IVM treatments are the young women undergoing anticancer therapy (radiation- or chemotherapy). Thus, ovarian and oocyte cryopreservation techniques are emerging, however such treatments can only be fully realized when IVM becomes an efficient means of obtaining healthy birth. At present, the In Vitro maturation techniques are highly successful in mice, variable successful in domestic species and still regarded experimental in the human clinic due to suboptimal fertilization rates and embryo quality. This review discusses comparative studies of the processes of oocyte maturation In Vivo and In Vitro, in various mammalian species including human. Among the substances that have been reported to influence oocyte maturation there is an interesting endogenous signaling molecule: FF-MAS (4,4-dimethyl-5 alpha-cholest-8,14,24-trien-3 beta -ol), an intermediate in the cholesterol biosynthetic pathway present in all cells. This review gives special focus to FF-MAS, the effect seen in animal and human studies so far and its potential use in

  9. International collaborative research on infectious diseases by Japanese universities and institutes in Asia and Africa, with a special emphasis on J-GRID.

    PubMed

    Shinoda, Sumio; Imamura, Daisuke; Mizuno, Tamaki; Miyoshi, Shin-Ichi; Ramamurthy, Thandavrayan

    2015-01-01

    In developed countries including Japan, malignant tumor (cancer), heart disease and cerebral apoplexy are major causes of death, but infectious diseases are still responsible for a high number of deaths in developing countries, especially among children aged less than 5 years. World Health Statistics published by WHO reports a high percentage of mortality from infectious diseases in children, and many of these diseases may be subject to transmission across borders and could possibly invade Japan.  Given this situation, the Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan initiated Phase I of the Program of Founding Research Centers for Emerging and Reemerging Infectious Disease, which ran from FY 2005 to 2009, and involved 8 Japanese universities and 2 research centers. The program was established for the following purposes: 1) creation of a domestic research structure to promote the accumulation of fundamental knowledge about infectious diseases, 2) establishment of 13 overseas research collaboration centers in 8 countries at high risk of emerging and reemerging infections and at which Japanese researchers are stationed and conduct research in partnership with overseas instructors, 3) development of a network among domestic and overseas research centers, and 4) development of human resources.  The program was controlled under MEXT and managed by the RIKEN Center of Research Network for Infectious Diseases (Riken CRNID). Phase II of the program was set up as the Japan Initiative for Global Research Network on Infectious Diseases (J-GRID), and has been running in FY 2010-2014.  Phase III will start in April 2015, and will be organized by the newly established Japanese governmental organization "Japan Agency for Medical Research and Development (AMED)", the so-called Japanese style NIH.  The Collaborative Research Center of Okayama University for Infectious Diseases in India (CRCOUI) was started up in 2007 at the National

  10. International collaborative research on infectious diseases by Japanese universities and institutes in Asia and Africa, with a special emphasis on J-GRID.

    PubMed

    Shinoda, Sumio; Imamura, Daisuke; Mizuno, Tamaki; Miyoshi, Shin-Ichi; Ramamurthy, Thandavrayan

    2015-01-01

    In developed countries including Japan, malignant tumor (cancer), heart disease and cerebral apoplexy are major causes of death, but infectious diseases are still responsible for a high number of deaths in developing countries, especially among children aged less than 5 years. World Health Statistics published by WHO reports a high percentage of mortality from infectious diseases in children, and many of these diseases may be subject to transmission across borders and could possibly invade Japan.  Given this situation, the Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan initiated Phase I of the Program of Founding Research Centers for Emerging and Reemerging Infectious Disease, which ran from FY 2005 to 2009, and involved 8 Japanese universities and 2 research centers. The program was established for the following purposes: 1) creation of a domestic research structure to promote the accumulation of fundamental knowledge about infectious diseases, 2) establishment of 13 overseas research collaboration centers in 8 countries at high risk of emerging and reemerging infections and at which Japanese researchers are stationed and conduct research in partnership with overseas instructors, 3) development of a network among domestic and overseas research centers, and 4) development of human resources.  The program was controlled under MEXT and managed by the RIKEN Center of Research Network for Infectious Diseases (Riken CRNID). Phase II of the program was set up as the Japan Initiative for Global Research Network on Infectious Diseases (J-GRID), and has been running in FY 2010-2014.  Phase III will start in April 2015, and will be organized by the newly established Japanese governmental organization "Japan Agency for Medical Research and Development (AMED)", the so-called Japanese style NIH.  The Collaborative Research Center of Okayama University for Infectious Diseases in India (CRCOUI) was started up in 2007 at the National

  11. 14 CFR Special Federal Aviation... - Process for Requesting Waiver of Mandatory Separation Age for a Federal Aviation Administration...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Separation Age for a Federal Aviation Administration Air Traffic Control Specialist In Flight Service... Federal Special Federal Aviation Regulation No. 103 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION..., SFAR 103 Special Federal Aviation Regulation No. 103—Process for Requesting Waiver of...

  12. 14 CFR Special Federal Aviation... - Process for Requesting Waiver of Mandatory Separation Age for a Federal Aviation Administration...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Separation Age for a Federal Aviation Administration Air Traffic Control Specialist In Flight Service... Federal Special Federal Aviation Regulation No. 103 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION..., SFAR No. 103 Special Federal Aviation Regulation No. 103—Process for Requesting Waiver of...

  13. 14 CFR Special Federal Aviation... - Process for Requesting Waiver of Mandatory Separation Age for a Federal Aviation Administration...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Separation Age for a Federal Aviation Administration Air Traffic Control Specialist In Flight Service... Federal Special Federal Aviation Regulation No. 103 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION..., SFAR 103 Special Federal Aviation Regulation No. 103—Process for Requesting Waiver of...

  14. 14 CFR Special Federal Aviation... - Process for Requesting Waiver of Mandatory Separation Age for a Federal Aviation Administration...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Separation Age for a Federal Aviation Administration Air Traffic Control Specialist In Flight Service... Federal Special Federal Aviation Regulation No. 103 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION..., SFAR No. 103 Special Federal Aviation Regulation No. 103—Process for Requesting Waiver of...

  15. 77 FR 55477 - Special Emphasis Panel Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-10

    ... for Sustainable Research and Dissemination of Evidence-Based Medicine (R24)''. DATES: September 20-21... Sustainable Research and Dissemination of Evidence-Based Medicine (R24)'' are to be reviewed and discussed...

  16. [Informed consent with special emphasis on Croatia].

    PubMed

    Vucemilo, Luka; Babić-Bosanac, Sanja; Altarac, Silvio; Borovecki, Ana

    2014-01-01

    Respecting the informed consent and its implementation is one of the fundamental components of high-quality health care. This article discusses the informed consent with an overview of Croatian and international legal documents and scientific studies dealing with this issue. Based on the review of the literature it can be concluded that this is an important issue that contains several key components that should be observed and investigated. It is necessary to evaluate the purposefulness and quality of the implementation of the informed consent, to systematically examine respect of the patients' right to information regarding the medical procedure during treatment, to explore decision-making model in the physician-patient encounter in Croatian hospitals, to determine the content and amount of information shared between physicians and patients, to determine the content and readability of consent forms and written patient information on the medical procedure. In order to assure higher quality of the implementation of the informed consent it is necessary to define by law a list of medical procedures that require written consent and to uniform consent forms for the same medical procedures country-wide.

  17. [Informed consent with special emphasis on Croatia].

    PubMed

    Vucemilo, Luka; Babić-Bosanac, Sanja; Altarac, Silvio; Borovecki, Ana

    2014-01-01

    Respecting the informed consent and its implementation is one of the fundamental components of high-quality health care. This article discusses the informed consent with an overview of Croatian and international legal documents and scientific studies dealing with this issue. Based on the review of the literature it can be concluded that this is an important issue that contains several key components that should be observed and investigated. It is necessary to evaluate the purposefulness and quality of the implementation of the informed consent, to systematically examine respect of the patients' right to information regarding the medical procedure during treatment, to explore decision-making model in the physician-patient encounter in Croatian hospitals, to determine the content and amount of information shared between physicians and patients, to determine the content and readability of consent forms and written patient information on the medical procedure. In order to assure higher quality of the implementation of the informed consent it is necessary to define by law a list of medical procedures that require written consent and to uniform consent forms for the same medical procedures country-wide. PMID:24988746

  18. Raising Reading Standards--The Reading Partners Approach: Cross-Age Peer Tutoring in a Special School.

    ERIC Educational Resources Information Center

    Nugent, Mary

    2001-01-01

    This article describes a cross-age peer tutoring program in reading developed and implemented at a special school for students (ages 8-18) with moderate learning difficulties in Ireland. Evaluation studies indicate multiple benefits accruing to both the learners and the helpers including progress in reading, enhanced feelings of self-worth, and…

  19. Euthanasia and assisted suicide: facts, figures and fancies with special regard to old age.

    PubMed

    Muller, M T; Kimsma, G K; van der Wal, G

    1998-09-01

    The objective of this paper is to describe the ethics and incidence of euthanasia and physician-assisted suicide (EAS) with special regard to old age. It is based on an assumption that if and when a practice of euthanasia and EAS is allowed, several vulnerable groups, including the elderly, may become a 'population at risk'. We describe some of these claims, and make an inventory of the arguments against a permissive policy concerning euthanasia and EAS which emphasise inherent dangers for the elderly. We then give an overview of the results of empirical studies about incidence of (request for) euthanasia and assisted suicide in the Netherlands, Australia, the UK, the US, Denmark and Norway. These results confirm that practitioners do receive requests for EAS and that EAS is performed in all these countries. However, there are large differences between these countries with regard to the numbers of requests and performances. Dutch findings concerning the age distribution of patients who received euthanasia or assisted suicide indicate that these procedures are rare in the elderly and in nursing homes. We conclude that, although euthanasia and assisted suicide are illegal, there is evidence that these practices occur in all countries studied. Most surveys on the incidence of euthanasia show lower figures than those in the Netherlands. Dutch studies do not provide any evidence for the elderly being in danger of becoming 'victims' of euthanasia or assisted suicide. PMID:9789722

  20. Changes in the occurrence of heavy metals in polar ice during the last climatic cycles, with special emphasis on the possible link between cosmic dust accretion rate and the 100kyr cycle

    NASA Astrophysics Data System (ADS)

    Gabrielli, P.; Barbante, C.; Planchon, F. A. M.; Ferrant, C. P.; Delmonte, B.; Boutron, C. F.

    2003-05-01

    During the last decades, ice cores drilled in Antarctica and in Greenland have provided time series of data that have allowed the characterisation of variations of natural and anthropogenic heavy metals in the past atmosphere. Nevertheless, the interactions of heavy metals with climate change and their transport patterns remain largely unknown during the last climatic cycles. Hereafter we present our project dealing with the assessment of past changes of various heavy metals in Antarctic and Greenland ice during the past = 500kyr anticipating some preliminary Zn measurements in the EPICA Dome C ice core back to about 200000years. In our project special emphasis is given to Pt group elements (PGE) that are tracers of interplanetary dust particles (IDPs). Tracers of crustal material, volcanic activity and ocean paleoproductivity are also investigated. At the moment we are focusing especially on the ongoing EPICA Dome C Antarctic ice core, decontaminating mechanically some section and perfonning preliminary measurements of Zn and Al using Graphite Fumace Atomic Absorption Spectrometry and adopting ultraclean procedures. These data confinn the prominent continental origin of Zn in the East Antarctic ice during the last and penultimate glacial period.

  1. 78 FR 75358 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-11

    ... Committee: National Institute on Aging Special Emphasis Panel; Vitamin D Trials. Date: January 30, 2014...@mail.nih.gov . (Catalogue of Federal Domestic Assistance Program Nos. 93.866, Aging Research,...

  2. Developments in Aging: 1974 and January-April 1975. A Report of the Special Committee on Aging. United States Senate Pursuant to S. Res. 267, March 1, 1974.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    The Special Committee on Aging, established in 1961 by Senate Resolution 33, Eighty-seventh Congress, was charged with making a full and complete study and investigation of problems and opportunities of older people, including problems and opportunities of maintaining health, of assuring adequate income, of finding employment, of engaging in…

  3. Developments in Aging: 1986. Volume 1. A Report of the Special Committee on Aging. United States Senate, One Hundredth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    This document is the first volume of a two-volume Senate report describing actions taken during 1986 by the Congress, the administration, and the Senate Special Committee on Aging which are significant to older Americans. It summarizes and analyzes federal policies and programs that are of continuing importance for older persons and their…

  4. Wisdom-related knowledge in a life review task: age differences and the role of professional specialization.

    PubMed

    Staudinger, U M; Smith, J; Baltes, P B

    1992-06-01

    The study adopts life review as an avenue to access wisdom-related knowledge and examines the contribution of age and type of professional specialization to individual differences in wisdom-related knowledge. Women from 2 age groups/cohorts (young, M = 32 years; old, M = 71 years) and different professional specializations (human services vs. nonhuman services) were asked to think aloud about the life review of a fictitious woman who was either young or old. Verbal protocols were scored on 5 wisdom-related criteria: factual and procedural knowledge about life, life-span contextualism, relativism of values, recognition, and management of uncertainty. Three major findings emerged. First, human-services professionals outperformed the control group. Second, old adults performed as well as young adults. Third, for older adults wisdom-related performance was enhanced by the match between their own age and the age of the fictitious character. PMID:1610516

  5. Medicare: Catastrophic Illness Insurance. Briefing Report to the Chairman, Special Committee on Aging, U.S. Senate.

    ERIC Educational Resources Information Center

    General Accounting Office, Washington, DC. Program Evaluation and Methodology Div.

    In response to a request by Senator John Melcher of the United States Senate Special Committee on Aging, the General Accounting Office (GAO) reviewed legislative proposals designed to protect Medicare enrollees from the financial hardships that often accompany catastrophic illness. The GAO originally examined six legislative proposals introduced…

  6. State Special Education Finance Systems, 1992-93.

    ERIC Educational Resources Information Center

    O'Reilly, Fran

    This report which describes state systems for financing special education programs for school-age children with disabilities, is based on a is based on a national survey of state directors of special education during the 1992-93 school year. Emphasis is on determining state funding formulas, recognizing that many states are currently in various…

  7. 76 FR 65203 - National Institute on Aging

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-20

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging ACTION: Notice of Closed... of Committee: National Institute on Aging Special Emphasis Panel; Mechanisms of Osteoporosis II. Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  8. 76 FR 21386 - National Institute on Aging

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-15

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Organelle Lifespan Mechanism II. Date: June... Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892...

  9. Geologic Reconnaissance of the Antelope-Ashwood Area, North-Central Oregon: With Emphasis on the John Day Formation of Late Oligocene and Early Miocene Age

    USGS Publications Warehouse

    Peck, Dallas L.

    1964-01-01

    This report briefly describes the geology of an area of about 750 square miles in Jefferson, Wasco, Crook, and Wheeler Counties, Oregon. About 16,000 feet of strata that range in age from pre-Tertiary to Quaternary are exposed. These include the following units: pre-Tertiary slate, graywacke, conglomerate, and meta-andesite; Clarno Formation of Eocene age - lava flows, volcanic breccia, tuff, and tuffaceous mudstone, chiefly of andesitic composition; John Day Formation of late Oligocene and early Miocene age - pyroclastic rocks, flows, and domes, chiefly of rhyolitic composition; Columbia River Basalt of middle Miocene age - thick, columnar jointed flows of very fine grained dense dark-gray basalt; Dalles Formation of Pliocene age - bedded tuffaceous sandstone, siltstone, and conglomerate; basalt of Pliocene or Pleistocene age - lava flows of porous-textured olivine basalt; and Quaternary loess, landslide debris, and alluvium. Unconformities separate pre-Tertiary rocks and Clarno Formation, Clarno and John Day Formations, John Day Formation and Columbia River Basalt, and Columbia River Basalt and Dalles Formation. The John Day Formation, the only unit studied in detail, consists of about 4,000 feet of tuff, lapilli tuff, strongly to weakly welded rhyolite ash flows, and less abundant trachyandesite flows and rhyolite flows and domes. The formation was divided into nine mappable members in part of the area, primarily on the basis of distinctive ledge-forming welded ash-flow sheets. Most of the sheets are composed of stony rhyolite containing abundant lithophysae and sparse phenocrysts. One sheet contains 10 to 20 percent phenocrysts, mostly cryptoperthitic soda sanidine, but including less abundant quartz, myrmekitic intergrowths of quartz and sanidine, and oligoclase. The rhyolitic ash flows and lava flows were extruded from nearby vents, in contrast to some of the interbedded air-fall tuff and lapilli tuff of dacitic and andesitic composition that may have been

  10. The role of time and time perspective in age-related processes: Introduction to the special issue.

    PubMed

    Fung, Helene H; Isaacowitz, Derek M

    2016-09-01

    There currently appears to be a general consensus on the relationship between time perspective and aging, such that (a) future time is perceived as more limited with age and (b) older people are more present-focused and less future-focused than younger people. At the same time, there are debates about whether these age differences are positively related to well-being and to what extent there are boundary conditions beyond which these age differences would cease to occur. The 8 manuscripts included in this Special Issue attempt to shed light on these debates. In doing so, they refine the dominant theoretical perspective on the topic-socioemotional selectivity theory-and introduce new theoretical perspectives. New measures and methodologies for studying time perspective and aging are also discussed. (PsycINFO Database Record PMID:27599019

  11. IDEA Special Education Mediation. A Guide for Parents of Children & Youth (Ages 3-21)

    ERIC Educational Resources Information Center

    Center for Appropriate Dispute Resolution in Special Education (CADRE), 2014

    2014-01-01

    This information guide was designed to assist in resolving special education disputes, as well as to provide dispute resolution options for parents or school district staff when communications are difficult or there is a dispute that cannot be resolved. Mediation is a voluntary process that (1) brings people together to resolve their…

  12. Rhinoplasty in the aging nose.

    PubMed

    Romo, Thomas; Soliemanzadeh, Peyman; Litner, Jason A; Sclafani, Anthony P

    2003-11-01

    The aging nose presents a difficult challenge for the rhinoplastic surgeon. To best address the patient's wishes, the surgeon must possess a sound understanding of the atrophic changes associated with the aging nose, including tip ptosis, increased nasal bulbosity, a lengthened nasal appearance, and altered nasal airflow patterns. Surgical emphasis is placed on conservative structured reduction to address functional concerns. Overresection risks destabilizing the nasal tip and altering the patient's concrete self-image. This article outlines our approach to rhinoplasty in the aging nose with a special emphasis on the use of porous polyethylene alloimplants to provide added structural support.

  13. The effect of aging on the specialized conducting system: a telemetry ECG study in rats over a 6 month period.

    PubMed

    Rossi, Stefano; Fortunati, Ilaria; Carnevali, Luca; Baruffi, Silvana; Mastorci, Francesca; Trombini, Mimosa; Sgoifo, Andrea; Corradi, Domenico; Callegari, Sergio; Miragoli, Michele; Macchi, Emilio

    2014-01-01

    Advanced age alone appears to be a risk factor for increased susceptibility to cardiac arrhythmias. We previously observed in the aged rat heart that sinus rhythm ventricular activation is delayed and characterized by abnormal epicardial patterns although conduction velocity is normal. While these findings relate to an advanced stage of aging, it is not yet known when and how ventricular electrical impairment originates and which is the underlying substrate. To address these points, we performed continuous telemetry ECG recordings in freely moving rats over a six-month period to monitor ECG waveform changes, heart rate variability and the incidence of cardiac arrhythmias. At the end of the study, we performed in-vivo multiple lead epicardial recordings and histopathology of cardiac tissue. We found that the duration of ECG waves and intervals gradually increased and heart rate variability gradually decreased with age. Moreover, the incidence of cardiac arrhythmias gradually increased, with atrial arrhythmias exceeding ventricular arrhythmias. Epicardial multiple lead recordings confirmed abnormalities in ventricular activation patterns, likely attributable to distal conducting system dysfunctions. Microscopic analysis of aged heart specimens revealed multifocal connective tissue deposition and perinuclear myocytolysis in the atria. Our results demonstrate that aging gradually modifies the terminal part of the specialized cardiac conducting system, creating a substrate for increased arrhythmogenesis. These findings may open new therapeutic options in the management of cardiac arrhythmias in the elderly population.

  14. 76 FR 34720 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-14

    ... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... Committee: National Institute on Aging Special Emphasis Panel, Frontotemporal Dementia. Date: July 26,...

  15. 75 FR 54160 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-03

    ... Committee: National Institute on Aging Special Emphasis Panel; Menopause and Sleep Disorders. Date: October... Effects of Early Education. Date: October 22, 2010. Time: 10 a.m. to 1 p.m. Agenda: To review and...

  16. Secular trend of the age at menarche of Japanese girls with special regard to the secular acceleration of the age at peak height velocity.

    PubMed

    Hoshi, H; Kouchi, M

    1981-12-01

    An attempt is made to clarify the special characteristics of the secular trend of the menarchial age in Japan. The relationships with the precocious appearance of the age at peak high velocity, another exemplification of the maturity acceleration, is also reviewed. This research on menarche was conducted in 1979-1980 on 284 school girls born between 1961 and 1966. The girls were healthy, of middle socioeconomic class, and grew up and lived in Tokyo and its outskirts. A questionnaire was given to each subject who was requested to answer after referring to her diary, mother's or sister's records, or any other writing about her menarche. If none of these was available, they were asked to provide an event which occurred soon before or after the menarche. The arithmetic mean of the age at menarche was 12.40 years with a range of 9.63 to 15.44 years. In 1958 research was conducted on the menarche of 309 girls in the same school, and the mean menarchial age was reported to be 13.27 years with a range of 10.83 to 16.92 years. The rate of acceleration during these 21 years was 4.4 months/decade. Mean menarchial ages obtained in 157 studies ever reported in Japan were plotted against the year of publication. No definite tendency was apparent until a gradual change toward earlier menstruation began in about 1920. In the next 20 years the average decreased from 15.0 to 14.2 years of age. The rate of decrease during the 1920-1940 period was about 4 months/decade. Due to World War 2, a retardation of menarche began in 1941 and reached a peak of about 15.0 years of age in 1950-1952, after which the trend changed into one of rapid acceleration. It is believed that the age at peak height velocity (PHV) is highly correlated with menarche age. The correlation coefficient is reported to be 0.71 by Nicholson and Hanly (1953), 0.93 by Deming (1957) and 0.77 by the author's of this study based on the present subjects. Thus it can be reasonably assumed that the secular trend of menarche

  17. Developments in Aging: 1989. Volume 1. A Report of the Special Committee on Aging, United States Senate, Pursuant to S. RES. 66, SEC. 19, February 28, 1989, Resolution Authorizing a Study of the Problems of the Aged and Aging. 101st Congress, 2d Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    This document contains the 1989 annual report of the Senate Special Committee on Aging. It describes actions during 1989 by the Congress, the federal administration, and the U.S. Senate Special Committee on Aging, which are significant to America's older citizens. It also summarizes and analyzes the federal policies and programs that are of the…

  18. Developments in Aging: 1989. Volume 2--Appendixes. A Report of the Special Committee on Aging, United States Senate, Pursuant to S. RES. 66, SEC. 19, February 28, 1989, Resolution Authorizing a Study of the Problems of the Aged and Aging. 101st Congress, 2d Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    This document contains the appendices to the 1989 annual report of the Senate Special Committee on Aging which: (1) describes actions during 1989 by the Congress, the federal administration, and the U.S. Senate Special Committee on Aging, that are significant to America's older citizens; and (2) summarizes and analyzes the federal policies and…

  19. Crisis Model for Older Adults: Special Considerations for an Aging Population

    ERIC Educational Resources Information Center

    Jungers, Christin M.; Slagel, Leslie

    2009-01-01

    As the U.S. population ages, counselors must begin structuring their interactions to meet the unique needs of older adults, especially in the area of crisis intervention. The purposes of this article are to draw attention to the rapidly growing, often disregarded older population and to introduce the Crisis Model for Older Adults (CM-OA), an…

  20. The Knowledge Institutions in the Information Age. The Special Case of the Public Library.

    ERIC Educational Resources Information Center

    Molz, R. Kathleen

    This essay explores the somewhat uneven course of the public library as a knowledge institution in America and its relevance during the current information age, particularly in the United States, where there is a basic connection between access to knowledge and the political system. The public library situation is considered in terms of the…

  1. 76 FR 30374 - National Institute on Aging; Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Meetings Notice of Closed... of Committee: National Institute on Aging Special Emphasis Panel; Member Conflict Sep. Date: June 2..., PhD, Chief, Scientific Review Branch, National Institute on Aging, National Institutes of...

  2. ADHD in school-aged youth: Management and special treatment considerations in the primary care setting.

    PubMed

    Weed, Elizabeth D

    2016-01-01

    Attention-deficit/hyperactivity disorder is considered one of the most common neurodevelopmental disorders of childhood. Primary care providers are in the unique position of providing comprehensive care-routine care, well child visits, immunizations, and other healthcare needs-to a majority of children and adolescents with attention-deficit/hyperactivity disorder. As such, primary care providers are pivotal in the diagnosis, management, and treatment of this population. This article will address special treatment considerations to aid in the management of attention-deficit/hyperactivity disorder in the primary care setting, including substance use disorders and diversion, cardiac issues and stimulant medication, medication holidays and follow-up monitoring. The database of PubMed was searched using keywords that included attention-deficit/hyperactivity disorder, children, prevalence, medication holidays, safety, cardiovascular, cardiac, blood pressure, substance use, diversion, adverse drug reactions; inclusion dates were January 1, 2011 to September 30, 2015.

  3. Training Needs in Gerontology; Hearing before the Special Committee on Aging, United States Senate, Ninety-Fourth Congress, First Session. Part 3--Washington, D.C.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    Hearing before the Senate Special Committee on Aging was held to consider the need for funds to provide professional training in the field of gerontology as authorized under the Older Americans Act. Provision for special skills training was made under title IV of the Act but no funds were included for it in the 1975 and 1976 budgets. A statement…

  4. Transportation in an aging society: improving mobility and safety for older persons. Volume 1. Committee report and recommendations. Special report

    SciTech Connect

    Not Available

    1988-01-01

    In June 1986, the Transportation Research Board began a project to investigate the needs and problems of older Americans in relation to the U.S. roadway-transportation system. A committee of experts was appointed to review the design and operational features of the roadway system and to recommend steps to improve the mobility and safety of older users--drivers, passengers, pedestrians--who are an integral part of the system. The committees found that people over the age of 75 are involved in more fatal crashes than any other group except teenagers. Nevertheless they decided that 'age alone is a poor predictor of the performance of any individual.' Rather than restricting licenses at any given maximum age, the committee recommended that highway safety be improved by making adjustments to the design of highway features and that license screening tests be adapted to better identify people of all ages who have impairments that would affect driving. The committee also recommended improved specialized transportation for the frail elderly.

  5. [Senescence-accelerated mouse (SAM): with special reference to age-associated pathologies and their modulation].

    PubMed

    Takeda, T

    1996-07-01

    The senescence-accelerated mouse (SAM) has been under development by our research team at Kyoto University since 1970 through selective inbreeding of the AKR/J strain of mice donated by the Jackson Laboratory in 1968, based on the data of the grading score of senescence, life span, and pathologic phenotypes. At present, there are 12 lines of SAM; the 9 senescence-prone inbred strains (SAMP) include SAMP1, SAMP2, SAMP3, SAMP6, SAMP7, SAMP8, SAMP9, SAMP10 and SAMP11, and the 3 senescence-resistant inbred strains (SAMR) SAMR1, SANR4 and SAMR5. Data from survival curves, the Gompertzian function and the grading score of senescence, together with growth patterns of body weight of these SAMP and SAMR mice revealed that the characteristic feature of aging common to all SAMP mice is "accelerated senescence": early onset and irreversible advance of senescence manifested by several signs and gross lesions such as the loss of normal behavior, various skin lesions, increased lordokyphosis, etc., after a period of normal development. Routine postmortem examinations and the pathobiological features revealed by systematically designed studies have shown several pathologic phenotypes, which are often characteristic enough to differentiate among the various SAM strains: senile amyloidosis in SAMP1, -P2, -P7, -P9, -P10 and -P11, secondary amyloidosis in SAMP2 and -P6, contracted kidney in SAMP1, -P2, -P10, -P11, immunoblastic lymphoma in SAMR1 and -R4, histiocytic sarcoma in SAMR1 and -R4, ovarian cysts in SAMR1, impaired immune response in SAMP1, -P2 and -P8, hyperinflation of the lungs in SAMP1, hearing impairment in SAMP1, degenerative temporomandibular joint disease in SAMP3, senile osteoporosis in SAMP6, deficits in learning and memory in SAMP8 and -P10, emotional disorders in SAMP8 and -P10, cataracts in SAMP9, and brain atrophy in SAMP10. These are all age-associated pathologies, the incidence and severity of which increase with advancing age. The SAM model in which these

  6. 75 FR 63497 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Genetic Determinants of Healthy Aging. Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  7. 77 FR 34394 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Healthy Aging and the Life Course. Date: June...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  8. 75 FR 39698 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-12

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel, Network Infrastructure for Aging Research...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  9. 77 FR 40370 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Aging and Innovation. Date: July 11, 2012... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, (Telephone...

  10. 78 FR 20669 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-05

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Management of the Primate Aging Database Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  11. 77 FR 63843 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-17

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Aging and Sleep. Date: November 8, 2012. Time... on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892,...

  12. 75 FR 67381 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-02

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel HIV, HAART and AGING. Date: November 23, 2010... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, (Telephone...

  13. 75 FR 79386 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Hormone Therapy and Cognitive Aging. Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  14. 76 FR 32977 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-07

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Aging and Economics. Date: June 24, 2011... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892 (Telephone...

  15. Women with epilepsy in reproductive age group: special issues and management strategies.

    PubMed

    Begum, Shehanaaz; Thomas, Sanjeev V

    2013-08-01

    Women with epilepsy (WWE) have several gender based problems pertaining to social and biological domains. The stigma of epilepsy and its consequences appear to be more for women than men. They have more difficulty in getting married and sustaining a married life. The cyclical variations in the reproductive hormones can adversely impact the seizure pattern in WWE. Epileptiform discharges in the brain can influence the hypothalamic functions and lead to sexual dysfunction. The Antiepileptic drugs (AED) may alter their metabolic and hormone profile and contribute to this disorder. Most WWE tend to have uneventful pregnancies and healthy babies. Nevertheless, the risk of fetal malformations appears to be increased when AEDs are used during pregnancy. This risk is higher for those who are on polytherapy, or using valproate. Recent studies have also demonstrated that antenatal exposure to AEDs could lead to neurocognitive and developmental impairment, low IQ or language problems in exposed infants. Clinicians need to consider these special issues while initiating AED therapy in adolescent girls. All WWE need to have a detailed pre conception evaluation wherein the need to continue AEDs, the ideal AED and dosage are reassessed. The AED therapy would have to be individualized according to the clinical situations, obstetric background and family concerns. Folic acid should be prescribed to all women who could potentially become pregnant. Detailed screening for fetal malformations by estimation of serum alpha fetoprotein and fetal ultrasonography need to be carried out between 14 - 18 weeks of pregnancy. The dosage of AEDs may have to be escalated in the second half of pregnancy in selected patients. The family should be provided detailed counseling and information on how to cope with the pregnancy, childbirth, lactation, and contraception. PMID:24818330

  16. Evaluation of systemic markers of inflammation in atomic-bomb survivors with special reference to radiation and age effects

    PubMed Central

    Hayashi, Tomonori; Morishita, Yukari; Khattree, Ravindra; Misumi, Munechika; Sasaki, Keiko; Hayashi, Ikue; Yoshida, Kengo; Kajimura, Junko; Kyoizumi, Seishi; Imai, Kazue; Kusunoki, Yoichiro; Nakachi, Kei

    2012-01-01

    Past exposure to atomic bomb (A-bomb) radiation has exerted various long-lasting deleterious effects on the health of survivors. Some of these effects are seen even after >60 yr. In this study, we evaluated the subclinical inflammatory status of 442 A-bomb survivors, in terms of 8 inflammation-related cytokines or markers, comprised of plasma levels of reactive oxygen species (ROS), interleukin (IL)-6, tumor necrosis factor α (TNF-α), C-reactive protein (CRP), IL-4, IL-10, and immunoglobulins, and erythrocyte sedimentation rate (ESR). The effects of past radiation exposure and natural aging on these markers were individually assessed and compared. Next, to assess the biologically significant relationship between inflammation and radiation exposure or aging, which was masked by the interrelationship of those cytokines/markers, we used multivariate statistical analyses and evaluated the systemic markers of inflammation as scores being calculated by linear combinations of selected cytokines and markers. Our results indicate that a linear combination of ROS, IL-6, CRP, and ESR generated a score that was the most indicative of inflammation and revealed clear dependences on radiation dose and aging that were found to be statistically significant. The results suggest that collectively, radiation exposure, in conjunction with natural aging, may enhance the persistent inflammatory status of A-bomb survivors.—Hayashi, T., Morishita, Y., Khattree, R., Misumi, M., Sasaki, K., Hayashi, I., Yoshida, K., Kajimura, J., Kyoizumi, S., Imai, K., Kusunoki, Y., Nakachi, K. Evaluation of systemic markers of inflammation in atomic-bomb survivors with special reference to radiation and age effects. PMID:22872680

  17. Five years of interdisciplinary research on ageing and technology: Outcomes of the Lower Saxony Research Network Design of Environments for Ageing (GAL)--an introduction to this Special Issue on Ageing and Technology.

    PubMed

    Haux, Reinhold; Hein, Andreas; Kolb, Gerald; Künemund, Harald; Eichelberg, Marco

    2014-01-01

    This Special Issue of Informatics for Health and Social Care is presenting outcomes of the Lower Saxony Research Network Design of Environments for Ageing (abbreviated as GAL), probably one of the largest inter- and multidisciplinary research projects on aging and technology. In order to investigate and provide answers on whether new information and communication technologies can contribute to keeping, or even improving quality of life, health and self-sufficiency in ageing societies through new ways of living and new forms of care, GAL had been established as a five-year research project, running from 2008 to 2013. Ambient-assisted living technologies in personal and home environments were especially important. During the five years of research in GAL, more than seventy researchers from computer science, economics, engineering, geriatrics, gerontology, informatics, medicine, nursing science and rehabilitation pedagogy intensively collaborated in finding answers.

  18. Developments in Aging: 1976. Part 1. A Report of the Special Committee on Aging, United States Senate, Pursuant to S. Res. 373, March 1, 1976 Resolution Authorizing a Study of the Problems of the Aged and Aging Together with Minority Views. 95th Congress, 1st Session. Report No. 95-88.

    ERIC Educational Resources Information Center

    1977

    The first part of a report by the Special Committee on Aging of the United States Senate provides additional evidence about the need for far-ranging federal attention to the needs and aspirations of older Americans. A number of difficulties such as special transportation needs in rural areas, contradictions in policies and programs, and disaster…

  19. Special session on environment and energy, and repeated emphasis from early-`80s onwards, hybrid-drive targets for penetrating beams, that encompasses ultra high intensity lasers and/or particle beams

    SciTech Connect

    Mark, J.W. ||

    1994-10-05

    In this special session, we discuss {bold global} {bold climate} {bold change} concerns, as well as {bold cleanup} {bold of} {bold wastes} {bold and}/{bold or} {bold toxic} {bold materials}, their relations to energy and other technologies. We especially bring together scientists to discuss available and/or developable technologies of amelioration or cleanup, for consideration of unusual uses of {bold Lasers}, {bold Particle} {bold Beams} {bold and} {bold other} {bold plasma} Phenomena. {copyright}{ital American} {ital Institute} {ital of} {ital Physics} 1994

  20. The Hallmarks of Aging

    PubMed Central

    López-Otín, Carlos; Blasco, Maria A.; Partridge, Linda; Serrano, Manuel; Kroemer, Guido

    2013-01-01

    Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. This deterioration is the primary risk factor for major human pathologies including cancer, diabetes, cardiovascular disorders, and neurodegenerative diseases. Aging research has experienced an unprecedented advance over recent years, particularly with the discovery that the rate of aging is controlled, at least to some extent, by genetic pathways and biochemical processes conserved in evolution. This review enumerates nine tentative hallmarks that represent common denominators of aging in different organisms, with special emphasis on mammalian aging. These hallmarks are: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication. A major challenge is to dissect the interconnectedness between the candidate hallmarks and their relative contribution to aging, with the final goal of identifying pharmaceutical targets to improve human health during aging with minimal side-effects. PMID:23746838

  1. 78 FR 69432 - National Institute on Aging; Cancellation of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-19

    ... November 8, 2013, 67177 FR 217. The meeting was entitled Member Conflict. Dated: November 13, 2013. Melanie... HUMAN SERVICES National Institutes of Health National Institute on Aging; Cancellation of Meeting Notice is hereby given of the cancellation of the National Institute on Aging Special Emphasis...

  2. Pharmacotherapy guidelines for the aged by family doctors for the use of family doctors: part C--Special pharmacology.

    PubMed

    Bergert, F W; Conrad, D; Ehrenthal, K; Fessler, J; Gross, J; Gundermann, K; Kluthe, B; Lang Heinrich, W; Liesenfeld, A; Loew, P G; Luther, E; Pchalek, R; Seffrin, J; Sterzing, A; Wolfring, H-J; Zimmermann, U

    2009-03-01

    The part "Special pharmacology of the aged" of this guideline contains recommendations for typical conditions in the family doctors practice: in the January issue 2009 dementia and Morbus Parkinson, in this issue osteoporosis and urinary incontinence and in the next issue rectal incontinence and obstipation. This issue of the IJCPT contains the third part of the Pharmacotherapy guidelines for the aged by family doctors for family doctors. Part 3: Osteoporosis and urinary incontinence. Osteoporosis is a systematic disease characterized by low bone mass and declining bone structure. Exercise, adequate diet, nicotine abstinence as well as reduction of alcohol consumption may counteract the progression of the disease. Osteoporosis manifests in bone fractures with minimal trauma. Attention must be given to the risk of falling, e.g., by avoiding drugs that increase the risk of falling: e.g., psychotropic agents, analgesic drugs and antiarrhythmic agents. Specific osteoporosis medication e.g. calcium, vitamin D, biphosphonates and SERM (selective estrogen receptor modulators) is evaluated by family doctors according to indication, dosage, contraindications, long-term therapy and nature of any fracture. Duration of therapy is at least 3 - max. 5 years followed by reassessment of indication. There are 3 types of urine incontinence (urge-, stress-, and overflow-incontinence). Another standardization of urinary incontinence follows dysfunctions of the pelvic floor: detrusor muscle-dependent, due to sphincter spasm, prostate gland dependent. Urge incontinence with a dysfunction of the detrusor muscle is the most common type. Mixed types are frequent. Non-drug measures (e.g. pelvic muscle training, bladder training, toilet training are first choice treatments. Drug therapy (estrogen, imipramine) are without proven effect.

  3. 78 FR 9708 - National Institute on Aging Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Comparative Physiology of Aging. Date:...

  4. 75 FR 26268 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel, ARRA--Behavioral Economics C.E.R.--Clinical.... Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C218, Bethesda,...

  5. 75 FR 35821 - National Institute On Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-23

    ... HUMAN SERVICES National Institutes of Health National Institute On Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel Member Conflict SEP, Date: June 24, 2010. Time...: Ramesh Vemuri, PhD, Chief, Scientific Review Branch, National Institute on Aging, National Institutes...

  6. 75 FR 11188 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel, Nursing Home Research. Date: May 7, 2010... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892. (Telephone...

  7. 78 FR 4423 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Worm Intervention Study. Date: February 20... Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda, MD 20892,...

  8. 77 FR 56855 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Skeletal Muscle. ] Date: October 23, 2012... Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892...

  9. 78 FR 51196 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-20

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Juvenile Protective Factors I. Date...: National Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda, MD...

  10. 77 FR 65005 - National Institute on Aging Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-24

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Juvenile Protective Factors. Date: December 4... Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892. Contact...

  11. 77 FR 1941 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-12

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; GEMSSTAR. Date: January 27, 2012. Time: 8 a.m...., Scientific Review Officer, National Institute on Aging, Gateway Building, Rm. 2C212, 7201 Wisconsin...

  12. 78 FR 36200 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-17

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Longitudinal Study Contract. Date: June 26... Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20814,...

  13. 77 FR 21790 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Loan Repayment 2012. Date: May 2, 2012. Time... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892. Contact Person:...

  14. 77 FR 53207 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-31

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Pepper Centers. Date: September 27-28, 2012... Branch, National Institute on Aging, 7201 Wisconsin Avenue, Suite 2c212, Bethesda, MD 20892,...

  15. 77 FR 2737 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Network Facilities for Developing Areas of Investigation in the Basic Biology of Aging. Date: February 9, 2012. Time: 8:30 a.m. to 9:30 a.m. Agenda:...

  16. 75 FR 25273 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel, Basis of Myocardial Injury in the Elderly...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  17. 76 FR 6628 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Sex Differences in Health and Survival. Date..., Scientific Review Officer, National Institutes on Aging, National Institutes of Health, 7201 Wisconsin...

  18. 77 FR 34396 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Changing Long Term Care in America. Date...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  19. 78 FR 9403 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-08

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; CALERIE Dataset. Date: March 7, 2013. Time: 1... Aging, Gateway Building, Room 2C212, 7201 Wisconsin Avenue, Bethesda, MD 20892, (Telephone...

  20. 77 FR 5030 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel Testosterone Studies. Date: February 16, 2012... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, (Telephone...

  1. 76 FR 5391 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Pepper Centers. Date: February 17-18, 2011..., Scientific Review Branch, National Institute on Aging, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  2. 76 FR 35901 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Signal Transduction. Date: July 12, 2011... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, (Telephone...

  3. 75 FR 11188 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Beeson Meeting. Date: April 28-29, 2010. Time..., Scientific Review Officer, National Institute on Aging, Scientific Review Branch, Gateway Building...

  4. 76 FR 28794 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-18

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Longevity Consortium. Date: June 9, 2011... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, (Telephone...

  5. 77 FR 31032 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-24

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Network Infrastructure Support. Date: June 7...., Scientific Review Officer, Scientific Review Branch, National Institute on Aging, Gateway Bldg., 2C212,...

  6. 75 FR 3476 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; Clinical Services. Date: January 29, 2010... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892. (Telephone...

  7. 76 FR 42719 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-19

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, The NIA Health and Retirement Study. Date.... Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda,...

  8. 78 FR 32408 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-30

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel Senile Dementia. Date: June 28, 2013. Time: 1... Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda, MD 20892, (Telephone...

  9. 75 FR 57965 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, Member Conflict SEP. Date: October 4, 2010... Review Branch, National Institute on Aging, National Institutes of Health, 7201 Wisconsin Avenue,...

  10. 76 FR 57064 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel, AD Genetics Warehouse. Date: October 7, 2011..., Scientific Review Officer, National Institute on Aging, Scientific Review Branch, Gateway Building...

  11. 78 FR 57167 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-17

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel; Disability and Employment. Date: October 17... Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda, MD 20892. Contact...

  12. 75 FR 39549 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-09

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel; ARRA--MIND MRI. Date: July 26, 2010. Time: 1... Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212. Bethesda, MD 20892. (Telephone...

  13. Work after 65: Options for the 80's. Hearing before the Special Committee on Aging, United States Senate, Ninety-Sixth Congress, Second Session. Part 3--Orlando, Fla.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    The problem of senior citizens in Florida who need to work are chronicled in this third part of the Senate Special Committee on Aging, Work after 65 hearings, conducted in Orlando, Florida, in July, 1980. During the Florida hearing, representatives of various government programs for senior citizens, professors of education and economics and…

  14. Effects of dry, vacuum, and special bag aging; USDA quality grade; and end-point temperature on yields and eating quality of beef Longissimus lumborum steaks.

    PubMed

    Dikeman, Michael E; Obuz, Ersel; Gök, Veli; Akkaya, Levent; Stroda, Sally

    2013-06-01

    This study evaluated the effects of three aging methods: (dry (D), wet (W), and special bag (SB)); two quality grades [USDA Choice((≥Small(50) marbling) and Select); and two cooked end-point temperatures (62.8 °C and 71.1 °C) on physico-chemical traits of instrumental tenderness, color, and sensory properties of Longissimus lumborum beef muscle. Dry-aged loins had higher (P<0.0001) weight loss than W or SB aged loins. However, D and SB aged loins had similar (P>0.05) combined losses. W aged loins had higher (P<0.01) L* values than D or SB aged loins. Warner-Bratzler shear force of steaks was not affected (P>0.05) by aging method or quality grade but increased (P<0.0001) as end-point temperature increased. Sensory panel evaluation also showed no effect (P>0.05) of aging method or quality grade on myofibrillar tenderness, juiciness, connective tissue amount, overall tenderness or off flavor intensity. Steaks cooked to 62.8 °C were juicier (P<0.05) than those cooked to 71.1 °C. Neither D nor SB aging had advantages over W aging.

  15. Effects of dry, vacuum, and special bag aging; USDA quality grade; and end-point temperature on yields and eating quality of beef Longissimus lumborum steaks.

    PubMed

    Dikeman, Michael E; Obuz, Ersel; Gök, Veli; Akkaya, Levent; Stroda, Sally

    2013-06-01

    This study evaluated the effects of three aging methods: (dry (D), wet (W), and special bag (SB)); two quality grades [USDA Choice((≥Small(50) marbling) and Select); and two cooked end-point temperatures (62.8 °C and 71.1 °C) on physico-chemical traits of instrumental tenderness, color, and sensory properties of Longissimus lumborum beef muscle. Dry-aged loins had higher (P<0.0001) weight loss than W or SB aged loins. However, D and SB aged loins had similar (P>0.05) combined losses. W aged loins had higher (P<0.01) L* values than D or SB aged loins. Warner-Bratzler shear force of steaks was not affected (P>0.05) by aging method or quality grade but increased (P<0.0001) as end-point temperature increased. Sensory panel evaluation also showed no effect (P>0.05) of aging method or quality grade on myofibrillar tenderness, juiciness, connective tissue amount, overall tenderness or off flavor intensity. Steaks cooked to 62.8 °C were juicier (P<0.05) than those cooked to 71.1 °C. Neither D nor SB aging had advantages over W aging. PMID:23501255

  16. Working Americans: Equality at Any Age. Hearing before the Special Committee on Aging, United States Senate, Ninety-Ninth Congress, Second Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    This report of a congressional hearing focuses on the Age Discrimination in Employment Act (ADEA), which permits forced retirement of American workers solely on the basis of age, that is, mandatory retirement at age 70. Testimony includes statements and prepared statements from a United States Representative, individuals who have been forced to…

  17. Morbillivirus infections, with special emphasis on morbilliviruses of carnivores.

    PubMed

    Barrett, T

    1999-09-01

    Morbilliviruses infections cause significant mortality in human beings and animals. Measles virus is responsible for up to two million childhood deaths annually in the developing world, while rinderpest and peste des petits ruminants cause severe epizootics in domestic and wild ruminants in areas of the world where they remain endemic. Canine distemper virus (CDV) is a cause of fatal disease in many species of carnivores. Distemper is controlled by vaccination in domestic dogs and farmed mink, but it may be impossible to eradicate the virus because of its global distribution and wide variety of susceptible host species, which includes both freshwater and marine seals. Research is currently under way to develop new recombinant vaccines, since the currently available live attenuated vaccines for CDV are not safe for use for all species and many valuable zoo animals need to be protected from CDV. New morbilliviruses with potentially disastrous ecological consequences for marine mammals have been discovered in the past decade; phocid distemper virus (PDV) in seals and the cetacean morbillivirus (CMV) has been found in dolphins, whales and porpoises. Reverse transcription, coupled with the polymerase chain reaction (RT/PCR) and nucleic acid sequencing, has been used to characterise the morbilliviruses and has given insights into the evolution of this virus genus. PMID:10515262

  18. A purview of waste management evolution: special emphasis on USA.

    PubMed

    Kollikkathara, Naushad; Feng, Huan; Stern, Eric

    2009-02-01

    The generation of waste in urban regions over time is seen to impact the balance of anthropogenic and natural resources. Various national and international initiatives to manage urban solid waste are in place and has thus have evolved at present to form an assortment of different subcomponents involving environmental, administrative, regulatory, scientific, market, technology, and socio-economic factors, which has increasing bearing on the US due to its volume and nature of discards. This paper draws together the various aspects of municipal solid waste (MSW) management as it evolved, particularly in the American society through reviewing works and findings. In many parts of the country, waste management at present, primarily involves landfilling, incineration with and without energy recovery, recycling and composting. Legislation, nature of wastes and market trends continue to redefine management operations and its responsibilities and impacts. Complexities are added to it by the nature of urban development as well. New studies and concepts like 3Rs, cradle-to-cradle, industrial ecology, and integrated waste management are adding new dimensions for solving waste problems towards achieving sustainable resource use. Local initiatives, both public and private are in the forefront of adopting alternate waste management procedures. The assistance from various government and private bodies, supporting shifts in waste management approaches, have immense value, as according to the new paradigms, nothing goes to waste. PMID:18796347

  19. A purview of waste management evolution: Special emphasis on USA

    SciTech Connect

    Kollikkathara, Naushad Feng, Huan; Stern, Eric

    2009-02-15

    The generation of waste in urban regions over time is seen to impact the balance of anthropogenic and natural resources. Various national and international initiatives to manage urban solid waste are in place and has thus have evolved at present to form an assortment of different subcomponents involving environmental, administrative, regulatory, scientific, market, technology, and socio-economic factors, which has increasing bearing on the US due to its volume and nature of discards. This paper draws together the various aspects of municipal solid waste (MSW) management as it evolved, particularly in the American society through reviewing works and findings. In many parts of the country, waste management at present, primarily involves landfilling, incineration with and without energy recovery, recycling and composting. Legislation, nature of wastes and market trends continue to redefine management operations and its responsibilities and impacts. Complexities are added to it by the nature of urban development as well. New studies and concepts like 3Rs, cradle-to-cradle, industrial ecology, and integrated waste management are adding new dimensions for solving waste problems towards achieving sustainable resource use. Local initiatives, both public and private are in the forefront of adopting alternate waste management procedures. The assistance from various government and private bodies, supporting shifts in waste management approaches, have immense value, as according to the new paradigms, nothing goes to waste.

  20. A review of plague persistence with special emphasis on fleas

    USGS Publications Warehouse

    Wimsatt, Jeffrey; Biggins, Dean E.

    2009-01-01

    Here, we note a potentially pivotal role for fleas. These epizootic plague vectors should be closely studied with newer more exacting methods to determine their potential to serve as participants in or accomplices to a plague persistence reservoir.

  1. A purview of waste management evolution: special emphasis on USA.

    PubMed

    Kollikkathara, Naushad; Feng, Huan; Stern, Eric

    2009-02-01

    The generation of waste in urban regions over time is seen to impact the balance of anthropogenic and natural resources. Various national and international initiatives to manage urban solid waste are in place and has thus have evolved at present to form an assortment of different subcomponents involving environmental, administrative, regulatory, scientific, market, technology, and socio-economic factors, which has increasing bearing on the US due to its volume and nature of discards. This paper draws together the various aspects of municipal solid waste (MSW) management as it evolved, particularly in the American society through reviewing works and findings. In many parts of the country, waste management at present, primarily involves landfilling, incineration with and without energy recovery, recycling and composting. Legislation, nature of wastes and market trends continue to redefine management operations and its responsibilities and impacts. Complexities are added to it by the nature of urban development as well. New studies and concepts like 3Rs, cradle-to-cradle, industrial ecology, and integrated waste management are adding new dimensions for solving waste problems towards achieving sustainable resource use. Local initiatives, both public and private are in the forefront of adopting alternate waste management procedures. The assistance from various government and private bodies, supporting shifts in waste management approaches, have immense value, as according to the new paradigms, nothing goes to waste.

  2. Distributed data base systems with special emphasis toward POREL

    NASA Technical Reports Server (NTRS)

    Neuhold, E. J.

    1984-01-01

    In the last few years a number of research and advanced development projects have resulted in distributed data base management prototypes. POREL, developed at the University of Stuttgart, is a multiuser, distributed, relational system developed for wide and local area networks of minicomputers and advanced micros. The general objectives of such data base systems and the architecture of POREL are discussed. In addition a comparison of some of the the existing distributed DMBS is included to provide the reader with information about the current state of the art.

  3. [Toxoplasmosis in pregnancy with special emphasis on laboratory diagnosis].

    PubMed

    Sibalić, D; Durković-Daković, O; Bobić, B

    1990-01-01

    On the occasion of the thirty-five years of systematic research of toxoplasmosis, a review of the present knowledge of the role of toxoplasmosis in pregnancy is presented. Diagnostic procedures and the interpretation of the results of laboratory examinations are particularly stressed. The main conclusion is that in a population exposed to the infection in the way as was in the cases studied, the prevention of congenital toxoplasmosis can be achieved through a serologic follow-up of all pregnant women starting from the moment when pregnancy is established. The purpose of such screening is to identify those pregnant women who are not immunized (who are then advised to follow certain hygienic and dietetic measures) and those who are primoinfected in pregnancy. As the latter are at risk for transmitting the infection to their fetuses, they receive specific therapy and their fetuses are carefully controlled by ultrasound and other methods for the antenatal diagnosis of intrauterine infection.

  4. Dengue hemorrhagic fever with special emphasis on immunopathogenesis.

    PubMed

    Kurane, Ichiro

    2007-09-01

    Dengue virus infections are a serious cause of morbidity and mortality in most tropical and subtropical areas of the world; Southeast and South Asia, Central and South America, and the Caribbean. Dengue virus infection can be asymptomatic or causes two forms of illness, dengue fever (DF) and dengue hemorrhagic fever (DHF), which is the severe form of dengue illness and often fatal. Pathogenesis of DHF has been analyzed, and two mechanisms are considered to be responsible. These include dengue serotype cross-reactive immune responses and virulence of the virus. The immunopathological mechanisms include a complex series of immune responses. Rapid increase in the levels of cytokines, especially TNF-alpha, and chemical mediators play a key role in inducing unique clinical manifestations of DHF such as plasma leakage, shock, and hemorrhagic manifestations. It is understood that the process is initiated by infection with a virulent dengue virus, often in the presence of antibodies that enhance dengue virus infection in secondary infection, and then triggered by rapidly elevated cytokines and chemical mediators that were produced by intense immune activation. However, complete understanding of the entire pathological mechanism is far from complete, and further studies are still needed.

  5. Synthetic fuels for ground transportation with special emphasis on hydrogen

    NASA Technical Reports Server (NTRS)

    Singh, J. J.

    1975-01-01

    The role of various synthetic fuels, for ground transportation in the United States, was examined for the near term (by 1985) and the longer term applications (1985-2000 and beyond 2000). Feasible options include synthetic oil, methanol, electric propulsion, and hydrogen. It is concluded that (1) the competition during the next 50 years will be for the fuels of all types, rather than among the fuels; (2) extensive domestic oil and gas exploration should be initiated concurrent with the development of several alternate fuels and related ancillaries; and (3) hydrogen, as an automotive fuel, seems to be equivalent to gasoline for optimum fuel to air mixtures. As a pollution free, high energy density fuel, hydrogen deserves consideration as the logical replacement for the hydrocarbons. Several research and development requirements, essential for the implementation of hydrogen economy for ground transportation, were identified. Extensive engineering development and testing activities should be initiated to establish hydrogen as the future automotive fuel, followed by demonstration projects and concerted efforts at public education.

  6. Thematic Emphasis in Language Production

    ERIC Educational Resources Information Center

    Vernice, Mirta; Pickering, Martin J.; Hartsuiker, Robert J.

    2012-01-01

    In three experiments, we investigate whether speakers tend to perseverate in the assignment of emphasis to concepts with particular thematic roles across utterances. Participants matched prime sentences involving clefts (e.g., "Het is de cowboy die hij slaat," "It is the cowboy that he is hitting") to pictures and then described unrelated…

  7. Future Trends in Scandinavian Special Education.

    ERIC Educational Resources Information Center

    Tuunainen, Kari

    1988-01-01

    The development of special education in Scandinavia is outlined, with special emphasis on Finland. Factors influencing the future of special education include emphasis on independent living, decreasing numbers of workers needed, increased mobility, disabled populations in third world countries, influence of information technology, etc. (Author/JDD)

  8. Obstacles a l'inclusion scolaire des enfants d'age prescolaire ayant des besoins speciaux. [Obstacles to Inclusion of Preschool-Age Special Needs Children.

    ERIC Educational Resources Information Center

    Tetreault, Sylvie; Beaupre, Pauline; Giroux, Martine; Gagne, Marie-eve; Guerard, Lucie

    2001-01-01

    Identifies obstacles faced by young children with special needs when trying to integrate into school. Proposes new strategies to prepare and support personnel involved during transition and inclusion in the school setting. Details group discussion of parents, care center educators, teachers, and administrators that resulted in a transition plan.…

  9. 78 FR 35041 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-11

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel SWAN. Date: June 27, 2013. Time: 9:30 a.m. to 12:30 p.m. Agenda: To review and evaluate grant applications. Place: National Institute on...

  10. 76 FR 23827 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-28

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Committee: National Institute on Aging Special Emphasis Panel Osteoarthritis. Date: June 8, 2011. Time: 9 a.m. to 1 p.m. Agenda: To review and evaluate grant applications. Place: National Institute on...

  11. 75 FR 18511 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-12

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel, Loan Repayment. Date: May 3, 2010. Time: 12 p.m. to 4 p.m. Agenda: To review and evaluate grant applications. Place: National Institute on...

  12. 78 FR 16273 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-14

    ... HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting... Committee: National Institute on Aging Special Emphasis Panel. Date: April 1, 2013. Time: 12:00 p.m. to 12:30 p.m. Agenda: To review and evaluate grant applications. Place: National Institute on...

  13. 77 FR 74677 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-17

    ... Committee: National Institute on Aging Special Emphasis Panel; Cell Dependent and Independent Mechanism... applications. Place: National Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue...:00 p.m. to 4:00 p.m. Agenda: To review and evaluate grant applications. Place: National Institute...

  14. 77 FR 14026 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-08

    ... Committee: National Institute on Aging Special Emphasis Panel; Reprogramming, Aging and Alzheimer's Disease... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  15. State Education Department--Oversight of School Districts' Special Education Classification and Placement Processes for School-Age Children. Report.

    ERIC Educational Resources Information Center

    New York State Office of the Comptroller, Albany. Div. of Management Audit and State Financial Services.

    This report presents findings of an audit of the New York State Education Department's Office of Vocational and Educational Services for Individuals with Disabilities (VESID). The audit concluded that VESID oversight of school districts may not be adequately targeting formal reviews of special education programs to those districts that pose the…

  16. Diagnostic History and Treatment of School-Aged Children with Autism Spectrum Disorder and Special Health Care Needs

    MedlinePlus

    ... 94:2–15. 2005. Myers SM, Johnson CP. Management of children with autism spectrum disorders. Pediatr 120(5):1162–82. 2007. McPherson M, Arango P, Fox H, Lauver C, et al. A new definition of children with special health care needs. Pediatr ...

  17. 1971 White House Conference on Aging. A Report to the Delegates from the Conference Sections and Special Concerns Sessions.

    ERIC Educational Resources Information Center

    White House Conference on Aging, Washington, DC.

    The two parts of this document contain reports relating to the normal concerns as well as the special concerns of the older adult population. In Part I, the reports discuss: Education; Employment and Retirement; Physical and Mental Health; Housing; Income; Nutrition; Retirement Roles and Activities; Spiritual Well-Being; Transportation;…

  18. A Parent's Guide to Services for Children, from Birth to Three Years of Age, with Special Needs

    ERIC Educational Resources Information Center

    Tennessee Department of Education, 2008

    2008-01-01

    This booklet introduces parents to "Tennessee's Early Intervention System" (TEIS). This system is funded through the Tennessee Department of Education. Through TEIS parents can get answers about their baby's growth and development and find the special services their child may need. Parents can also use this system to determine which other services…

  19. Early Childhood Education for Handicapped Children (Ages 3 through 5). Special Education in North Dakota. Guide VII.

    ERIC Educational Resources Information Center

    Niebergall, Shelby; Oas, Brenda

    This guide is designed primarily for use by personnel involved in North Dakota public school programs for preschool-age handicapped children (ages 3-5). It is also intended to provide parents and personnel in health, human services, and other child service agencies with an understanding of the scope and purpose of educational services for young…

  20. MitoAge: a database for comparative analysis of mitochondrial DNA, with a special focus on animal longevity

    PubMed Central

    Toren, Dmitri; Barzilay, Thomer; Tacutu, Robi; Lehmann, Gilad; Muradian, Khachik K.; Fraifeld, Vadim E.

    2016-01-01

    Mitochondria are the only organelles in the animal cells that have their own genome. Due to a key role in energy production, generation of damaging factors (ROS, heat), and apoptosis, mitochondria and mtDNA in particular have long been considered one of the major players in the mechanisms of aging, longevity and age-related diseases. The rapidly increasing number of species with fully sequenced mtDNA, together with accumulated data on longevity records, provides a new fascinating basis for comparative analysis of the links between mtDNA features and animal longevity. To facilitate such analyses and to support the scientific community in carrying these out, we developed the MitoAge database containing calculated mtDNA compositional features of the entire mitochondrial genome, mtDNA coding (tRNA, rRNA, protein-coding genes) and non-coding (D-loop) regions, and codon usage/amino acids frequency for each protein-coding gene. MitoAge includes 922 species with fully sequenced mtDNA and maximum lifespan records. The database is available through the MitoAge website (www.mitoage.org or www.mitoage.info), which provides the necessary tools for searching, browsing, comparing and downloading the data sets of interest for selected taxonomic groups across the Kingdom Animalia. The MitoAge website assists in statistical analysis of different features of the mtDNA and their correlative links to longevity. PMID:26590258

  1. Sources of tooth wear variation early in life among known-aged wild ring-tailed lemurs (Lemur catta) at the Bezà Mahafaly Special Reserve, Madagascar.

    PubMed

    Cuozzo, Frank P; Head, Brian R; Sauther, Michelle L; Ungar, Peter S; O'Mara, M Teague

    2014-11-01

    Ring-tailed lemurs (Lemur catta) at the Bezà Mahafaly Special Reserve (BMSR), Madagascar display a high frequency of individuals with notable and sometimes extreme tooth wear. Adult lemurs display a range of tooth wear even among individuals of the same age, but we do not know at what age this variation first appears. This study's goal was to determine whether wear variation occurs in younger wild lemurs. Based on the decade-long study of ring-tailed lemur feeding and dental ecology at BMSR, we hypothesized that younger, natal lemurs (under 5 years of age), would display variation in their degree of tooth wear that would correspond to microhabitat differences, given differences in food availability in different troops' home ranges. We also hypothesized that wear would differ between sexes at this young age, given differences in feeding between males and females in this population. Hypotheses were tested using dental topographic analyses using dental impressions collected from known-aged lemurs across 10 years at BMSR. Results illustrate significant differences in wear-related tooth topography (i.e., relief and slope, presented here as "occlusal lift") for microhabitat, sex and troop affiliation among lemurs under 5 years of age in this population. Although, all lemurs in this population consume mechanically challenging tamarind fruit, those in more disturbed habitats eat additional introduced foods, some of which are also mechanically challenging. Thus, dietary variation is the likely cause of variation in tooth wear. The wear variation we show at a young age suggests caution when assigning age based on tooth wear in living and fossil primates. These wear-related tooth shape changes early in life, which reflects sex, habitat variation and levels of anthropogenic disturbance, may potentially impact reproductive fitness later in life.

  2. Sources of tooth wear variation early in life among known-aged wild ring-tailed lemurs (Lemur catta) at the Bezà Mahafaly Special Reserve, Madagascar.

    PubMed

    Cuozzo, Frank P; Head, Brian R; Sauther, Michelle L; Ungar, Peter S; O'Mara, M Teague

    2014-11-01

    Ring-tailed lemurs (Lemur catta) at the Bezà Mahafaly Special Reserve (BMSR), Madagascar display a high frequency of individuals with notable and sometimes extreme tooth wear. Adult lemurs display a range of tooth wear even among individuals of the same age, but we do not know at what age this variation first appears. This study's goal was to determine whether wear variation occurs in younger wild lemurs. Based on the decade-long study of ring-tailed lemur feeding and dental ecology at BMSR, we hypothesized that younger, natal lemurs (under 5 years of age), would display variation in their degree of tooth wear that would correspond to microhabitat differences, given differences in food availability in different troops' home ranges. We also hypothesized that wear would differ between sexes at this young age, given differences in feeding between males and females in this population. Hypotheses were tested using dental topographic analyses using dental impressions collected from known-aged lemurs across 10 years at BMSR. Results illustrate significant differences in wear-related tooth topography (i.e., relief and slope, presented here as "occlusal lift") for microhabitat, sex and troop affiliation among lemurs under 5 years of age in this population. Although, all lemurs in this population consume mechanically challenging tamarind fruit, those in more disturbed habitats eat additional introduced foods, some of which are also mechanically challenging. Thus, dietary variation is the likely cause of variation in tooth wear. The wear variation we show at a young age suggests caution when assigning age based on tooth wear in living and fossil primates. These wear-related tooth shape changes early in life, which reflects sex, habitat variation and levels of anthropogenic disturbance, may potentially impact reproductive fitness later in life. PMID:24953664

  3. Working memory in children: tracing age differences and special educational needs to parameters of a formal model.

    PubMed

    Göthe, Katrin; Esser, Günther; Gendt, Anja; Kliegl, Reinhold

    2012-03-01

    Parameters of a formal working-memory model were estimated for verbal and spatial memory updating of children. The model proposes interference though feature overwriting and through confusion of whole elements as the primary cause of working-memory capacity limits. We tested 2 age groups each containing 1 group of normal intelligence and 1 deficit group. For young children the deficit was developmental dyslexia; for older children it was a general learning difficulty. The interference model predicts less interference through overwriting but more through confusion of whole elements for the dyslexic children than for their age-matched controls. Older children exhibited less interference through confusion of whole elements and a higher processing rate than young children, but general learning difficulty was associated with slower processing than in the age-matched control group. Furthermore, the difference between verbal and spatial updating mapped onto several meaningful dissociations of model parameters.

  4. Evaluation of systemic markers of inflammation in atomic-bomb survivors with special reference to radiation and age effects.

    PubMed

    Hayashi, Tomonori; Morishita, Yukari; Khattree, Ravindra; Misumi, Munechika; Sasaki, Keiko; Hayashi, Ikue; Yoshida, Kengo; Kajimura, Junko; Kyoizumi, Seishi; Imai, Kazue; Kusunoki, Yoichiro; Nakachi, Kei

    2012-11-01

    Past exposure to atomic bomb (A-bomb) radiation has exerted various long-lasting deleterious effects on the health of survivors. Some of these effects are seen even after >60 yr. In this study, we evaluated the subclinical inflammatory status of 442 A-bomb survivors, in terms of 8 inflammation-related cytokines or markers, comprised of plasma levels of reactive oxygen species (ROS), interleukin (IL)-6, tumor necrosis factor α (TNF-α), C-reactive protein (CRP), IL-4, IL-10, and immunoglobulins, and erythrocyte sedimentation rate (ESR). The effects of past radiation exposure and natural aging on these markers were individually assessed and compared. Next, to assess the biologically significant relationship between inflammation and radiation exposure or aging, which was masked by the interrelationship of those cytokines/markers, we used multivariate statistical analyses and evaluated the systemic markers of inflammation as scores being calculated by linear combinations of selected cytokines and markers. Our results indicate that a linear combination of ROS, IL-6, CRP, and ESR generated a score that was the most indicative of inflammation and revealed clear dependences on radiation dose and aging that were found to be statistically significant. The results suggest that collectively, radiation exposure, in conjunction with natural aging, may enhance the persistent inflammatory status of A-bomb survivors.

  5. Special Issue: Intellectual Property in the Information Age: Knowledge as Commodity and its Legal Implications for Higher Education

    ERIC Educational Resources Information Center

    Sun, Jeffrey C., Ed.; Baez, Benjamin, Ed.

    2009-01-01

    This monograph examines in great detail two kinds of intellectual property: copyrights and patents. Though the authors recognize the significance of trademarks and trade secrets, they focus primarily on copyrights and patents in this monograph because they represent the most significant issues in higher education in the information age.…

  6. Evaluation of systemic markers of inflammation in atomic-bomb survivors with special reference to radiation and age effects.

    PubMed

    Hayashi, Tomonori; Morishita, Yukari; Khattree, Ravindra; Misumi, Munechika; Sasaki, Keiko; Hayashi, Ikue; Yoshida, Kengo; Kajimura, Junko; Kyoizumi, Seishi; Imai, Kazue; Kusunoki, Yoichiro; Nakachi, Kei

    2012-11-01

    Past exposure to atomic bomb (A-bomb) radiation has exerted various long-lasting deleterious effects on the health of survivors. Some of these effects are seen even after >60 yr. In this study, we evaluated the subclinical inflammatory status of 442 A-bomb survivors, in terms of 8 inflammation-related cytokines or markers, comprised of plasma levels of reactive oxygen species (ROS), interleukin (IL)-6, tumor necrosis factor α (TNF-α), C-reactive protein (CRP), IL-4, IL-10, and immunoglobulins, and erythrocyte sedimentation rate (ESR). The effects of past radiation exposure and natural aging on these markers were individually assessed and compared. Next, to assess the biologically significant relationship between inflammation and radiation exposure or aging, which was masked by the interrelationship of those cytokines/markers, we used multivariate statistical analyses and evaluated the systemic markers of inflammation as scores being calculated by linear combinations of selected cytokines and markers. Our results indicate that a linear combination of ROS, IL-6, CRP, and ESR generated a score that was the most indicative of inflammation and revealed clear dependences on radiation dose and aging that were found to be statistically significant. The results suggest that collectively, radiation exposure, in conjunction with natural aging, may enhance the persistent inflammatory status of A-bomb survivors. PMID:22872680

  7. Subduction of Young Lithosphere at Critical Thermal Ages (10-20 Ma): Incites From Thermal Models and the Trans-Mexican Subduction System with Emphasis on the Importance of Slab Travel Times

    NASA Astrophysics Data System (ADS)

    Grose, C. J.

    2007-12-01

    The Trans-Mexican Volcanic Belt (TMVB) is a system where the age range of subducting plates is typically thought of as critical in their relation to lithospheric thermal structure (~10-20 Ma). I refer to this age range as "critical" because it is in this range where thermal lithospheres begin to rapidly decrease their correlative influence on the thermal state of the subduction system above the crust/mantle wedge interface for most systems. After ~20 Ma the cool upper portion of downgoing lithosphere becomes sufficiently thick so that crustal reheating and corresponding heat flow in the time between trench subduction and the zone of melt generation, due to the accumulation of conductive and frictional heating, behaves somewhat similarly with little regard to age. Typical slab travel times are on the order of 1.5-2.5 My. However, low dip angles and flat-slab behavior in the Eastern end of the TMVB facilitates anomalously long travel times exceeding 6.5 My! Here I show that while the influence of plate age is clearly significant in determining the holistic thermal geodynamics of subduction systems, the influence can be dampened or enhanced by auxiliary factors. I present thermal modeling cases using a solution for the conduction of heat into an evolving semi-infinite half-space with variable boundary conditions. Preliminary results indicate that extraordinary slab travel times and flat-slab behavior, mantle wedge advection regimes, and plate age thermally enhance and dampen each other. Geochemically, the TMVB shows consistent along-arc changes in light element abundance systematics (B/Be, Li/Yb, Be/Zr). Moderately elevated B/Be (Easterly increases from ~4 to ~12 ppm B/Be) observed in the eastern shallow subduction region is thought to correlate with subduction of an older, cooler portion of the slab. However, greater slab travel times in the Eastern TVMB should simultaneously act to warm the slab and depreciate these values which may partly explain the minimal

  8. African ethnobotany and healthcare: emphasis on mozambique.

    PubMed

    Bandeira, S O; Gaspar, F; Pagula, F P

    2001-01-01

    The relationship between common medicinal plants and major health problems in Africa, specifically Mozambique, is presented here. Emphasis is given to plant species largely used to solve or slow down diarrhoea, malaria, respiratory, and sexual complaints. These diseases, together with malnutrition/ anaemia, mental diseases, and rheumatism/arthritis are the main concern of healthcare countrywide. Diarrhoea is divided into common diarrhoea, bloody-diarrhoea, and cholera; plant species are normally used to slow down diarrhoea recurrence. Tannin is the main chemical compound with both anti-diarrhoeal and antiseptic properties. Traditional medicine seems to be rather helpful in alleviating malaria symptoms such as fever, vomiting, and diarrhoea. Special reference is made to Momordica balsamina, which is highly used to cure vomiting apparently associated with bilis and fever. Rauvolfia caffra contains reserpine, a compound used as anti-hypertension agent. This species is also used as an anti-malarial agent. Traditional medicine seems to have a role in slowing opportunistic infections related to the AIDS virus such as diarrhoea, pneumonia, and skin infections. Prostate hypertrophy is traditionally medicated using mostly Prunus africana and Hypoxis hemerocallidea, species known to contain phytosterol. Research for bioactive compounds in African plants is still in its infancy.

  9. [White House Conference on Aging, 1981. Creating an Age Integrated Society: Implications for the Media. Report and Executive Summary of the Technical Committee.

    ERIC Educational Resources Information Center

    Tanenbaum, Marc H.; And Others

    The relationship of older Americans to the new media culture of society is the focus of this Technical Committee Report. The work of two committee-appointed subcommittees on stereotypes and new media technology are explained with a special emphasis on the influence of television. Age stereotyping is examined in prime time television, daytime…

  10. The Older Americans Act and Its Application to Native Americans. Hearing before the Special Committee on Aging. United States Senate, Ninety-Ninth Congress, Second Session (Oklahoma City, OK, June 28, 1986).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    Three panels appearing before the Senate Special Committee on Aging discuss the sensitivity of the Administration on Aging to Native Americans, coordination of services between Title II and Title VI of the Older Americans Act, and availability of services under the act. Witnesses recommend language be included in the reauthorization of the Older…

  11. An aging population and growing disease burden will require a large and specialized health care workforce by 2025.

    PubMed

    Dall, Timothy M; Gallo, Paul D; Chakrabarti, Ritasree; West, Terry; Semilla, April P; Storm, Michael V

    2013-11-01

    As the US population ages, the increasing prevalence of chronic disease and complex medical conditions will have profound implications for the future health care system. We projected future prevalence of selected diseases and health risk factors to model future demand for health care services for each person in a representative sample of the current and projected future population. Based on changing demographic characteristics and expanded medical coverage under the Affordable Care Act, we project that the demand for adult primary care services will grow by approximately 14 percent between 2013 and 2025. Vascular surgery has the highest projected demand growth (31 percent), followed by cardiology (20 percent) and neurological surgery, radiology, and general surgery (each 18 percent). Market indicators such as long wait times to obtain appointments suggest that the current supply of many specialists throughout the United States is inadequate to meet the current demand. Failure to train sufficient numbers and the correct mix of specialists could exacerbate already long wait times for appointments, reduce access to care for some of the nation's most vulnerable patients, and reduce patients' quality of life. PMID:24191094

  12. Dopamine and aging: intersecting facets.

    PubMed

    Rollo, C David

    2009-04-01

    Aging encompasses life itself so understanding requires frameworks that forge unity amidst complexity. The free radical theory of aging is one example. The original focus on damage was augmented recently by appreciation that reactive oxygen and nitrogen species are essential to normal signaling and cell function. This paradigm is currently undergoing an explosive expansion fueled by the discovery that regulatory organization is a merry-go-round of redox cycling seamlessly fused to endogenous clocks. This might best be described as an "Electroplasmic Cycle." This is certainly applicable to dopaminergic neurons with their exceptional metabolic, electrical and rhythmic properties. Here I review normal aging of dopamine systems to highlight them as a valuable model. I then examine the possible integration of free radical and ion channel theories of aging. Finally, I incorporate clocks and explore the multifaceted implications of electroplasmic cycles with special emphasis on dopamine.

  13. Age at Autism Spectrum Disorder (ASD) Diagnosis by Race, Ethnicity, and Primary Household Language Among Children with Special Health Care Needs, United States, 2009-2010.

    PubMed

    Jo, Heejoo; Schieve, Laura A; Rice, Catherine E; Yeargin-Allsopp, Marshalyn; Tian, Lin H; Blumberg, Stephen J; Kogan, Michael D; Boyle, Coleen A

    2015-08-01

    We examined prevalence of diagnosed autism spectrum disorder (ASD) and age at diagnosis according to child's race/ethnicity and primary household language. From the 2009-2010 National Survey of Children with Special Health Care Needs, we identified 2729 3-17-year-old US children whose parent reported a current ASD diagnosis. We compared ASD prevalence, mean diagnosis age, and percentage with later diagnoses (≥5 years) across racial/ethnic/primary household language groups: non-Hispanic-white, any language (NHW); non-Hispanic-black, any language (NHB); Hispanic-any-race, English (Hispanic-English); and Hispanic-any-race, other language (Hispanic-Other). We assessed findings by parent-reported ASD severity level and adjusted for family sociodemographics. ASD prevalence estimates were 15.3 (NHW), 10.4 (NHB), 14.1 (Hispanic-English), and 5.2 (Hispanic-Other) per 1000 children. Mean diagnosis age was comparable across racial/ethnic/language groups for 3-4-year-olds. For 5-17-year-olds, diagnosis age varied by race/ethnicity/language and also by ASD severity. In this group, NHW children with mild/moderate ASD had a significantly higher proportion (50.8 %) of later diagnoses than NHB (33.5 %) or Hispanic-Other children (18.0 %). However, NHW children with severe ASD had a comparable or lower (albeit non-significant) proportion (16.4 %) of later diagnoses than NHB (37.8 %), Hispanic-English (30.8 %), and Hispanic-Other children (12.0 %). While NHW children have comparable ASD prevalence and diagnosis age distributions as Hispanic-English children, they have both higher prevalence and proportion of later diagnoses than NHB and Hispanic-Other children. The diagnosis age findings were limited to mild/moderate cases only. Thus, the prevalence disparity might be primarily driven by under-representation (potentially under-identification) of older children with mild/moderate ASD in the two minority groups.

  14. 75 FR 16489 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-01

    ...: National Institute on Aging Special Emphasis Panel; Diet Restriction. Date: May 6, 2010. Time: 1 p.m. to 4... and Dementia. Date: May 17, 2010. Time: 11 a.m. to 2 p.m. Agenda: To review and evaluate...

  15. 78 FR 30932 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meetings... Special Emphasis Panel; Heart Failure and Obesity. Date: July 10, 2013. Time: 1:00 p.m. to 5:00...

  16. 78 FR 63999 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ... Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's Disease Sequencing Project. Date... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  17. 78 FR 66015 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-04

    ... Committee: National Institute on Aging Special Emphasis Panel; Drug Development for Alzheimer's Disease... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  18. 76 FR 17929 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-31

    ... Committee: National Institute on Aging Special Emphasis Panel; Drug Development for Alzheimer's Disease... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  19. 76 FR 19105 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-06

    ... Committee: National Institute on Aging Special Emphasis Panel; Pathobiology of Alzheimer's Disease. Date... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  20. 77 FR 21790 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-11

    ... Committee: National Institute on Aging Special Emphasis Panel; Pathology of Alzheimer's Disease. Date: May 7... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  1. 77 FR 56856 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's Network. Date: October 4, 2012... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  2. 76 FR 28236 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-16

    ... Committee: National Institute on Aging Special Emphasis Panel, Pathology of Alzheimer's Disease. Date: June... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  3. 77 FR 26770 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-07

    ... Committee: National Institute on Aging Special Emphasis Panel; Presenilin and Alzheimer's Disease. Date... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  4. 77 FR 9670 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-17

    ... Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's Prevention. Date: March 1, 2012... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  5. 76 FR 1625 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-11

    ... Committee: National Institute on Aging Special Emphasis Panel; Drug Development for Alzheimer's Disease 2011... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  6. 77 FR 29677 - National Institute on Aging Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    ....gov . Name of Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's Disease Study... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  7. 75 FR 56116 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... Committee: National Institute on Aging Special Emphasis Panel, Alzheimer's Disease Genetics. Date: October 4... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  8. 78 FR 62639 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-22

    ... of Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's Disease Research... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  9. 77 FR 50704 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... Committee: National Institute on Aging Special Emphasis Panel, Drug Development for Alzheimer's Disease... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is... provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The...

  10. A synopsis on aging-Theories, mechanisms and future prospects.

    PubMed

    da Costa, João Pinto; Vitorino, Rui; Silva, Gustavo M; Vogel, Christine; Duarte, Armando C; Rocha-Santos, Teresa

    2016-08-01

    Answering the question as to why we age is tantamount to answering the question of what is life itself. There are countless theories as to why and how we age, but, until recently, the very definition of aging - senescence - was still uncertain. Here, we summarize the main views of the different models of senescence, with a special emphasis on the biochemical processes that accompany aging. Though inherently complex, aging is characterized by numerous changes that take place at different levels of the biological hierarchy. We therefore explore some of the most relevant changes that take place during aging and, finally, we overview the current status of emergent aging therapies and what the future holds for this field of research. From this multi-dimensional approach, it becomes clear that an integrative approach that couples aging research with systems biology, capable of providing novel insights into how and why we age, is necessary. PMID:27353257

  11. Punctuation and Process: A Matter of Emphasis.

    ERIC Educational Resources Information Center

    Schafer, John C.

    1988-01-01

    Argues that emphasis on process has reduced the amount of time teachers spend teaching basic editing skills. Offers eight suggestions for incorporating instruction in punctuation into a process approach to writing. (MS)

  12. Special Days, Special Ways.

    ERIC Educational Resources Information Center

    Clarke, Jacqueline

    2001-01-01

    Presents unique ways to create special rituals that recognize individual students' achievements and milestones. Ideas include throwing a send-off party for a student who is moving; holding monthly birthday luncheons; choosing an ambassador to accompany new students around school; and making a lost tooth container that students can use to safely…

  13. Our Greatest Generation: Continuing a Lifetime of Service. Hearing before the Special Committee on Aging. United States Senate, One Hundred Seventh Congress, First Session (Indianapolis, Indiana, August 9, 2001).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    This Congressional report contains the remarks made at a special meeting of the United States Committee on Aging to celebrate senior citizen's service to their community and examine policies regarding federally funded senior service programs. The following are among the programs, agencies, and organizations represented: Senior Companion Program;…

  14. Older Americans Act Amendments of 1987: A Summary of Provisions. Public Law 100-175. An Information Paper Prepared for Use by the Special Committee on Aging. United States Senate, 100th Congress, 1st Session.

    ERIC Educational Resources Information Center

    O'Shaughnessy, Carol

    The Older American Act Amendments of 1987 (Public Law 100-175) contain no major overhaul of the Act, but new provisions do significantly expand certain service components of the state and area agency on aging program under title III to address the special needs of certain populations, including the frail elderly living at home, residents of…

  15. Improving Legal Representation for Older Americans. Hearing Before the Special Committee on Aging, United States Senate, Ninety-Fourth Congress, Second Session. Part 2--Boston, Mass., August 30, 1976.

    ERIC Educational Resources Information Center

    1977

    The minutes of the meeting of the Special Committee on Aging of the U.S. Senate on the issue of legal services programs for the elderly, specifically programs in effect in the Boston area include statements made by the following: (1) an elderly diabetic woman testifying about living conditions and lack of services in her housing project; (2) the…

  16. Special Education through Neighbourhood Centers in Algeria.

    ERIC Educational Resources Information Center

    Boucebci, Mahfoud

    1981-01-01

    The article provides a survey of special education needs in Algeria with emphasis on the role of neighborhood centers which involve parents in the education of mentally handicapped children. Journal availability: see EC 133 861. (DB)

  17. The Biology of Aging.

    ERIC Educational Resources Information Center

    Sprott, Richard L.; And Others

    1992-01-01

    Thirteen articles in this special issue discuss aging theories, biomarkers of aging, aging research, disease, cancer biology, Alzheimer's disease, stress, oxidation of proteins, gene therapy, service delivery, biogerontology, and ethics and aging research. (SK)

  18. The Influence of Child, Family, Home Factors and Pre-School Education on the Identification of Special Educational Needs at Age 10

    ERIC Educational Resources Information Center

    Anders, Yvonne; Sammons, Pam; Taggart, Brenda; Sylva, Kathy; Melhuish, Edward; Siraj-Blatchford, Iram

    2011-01-01

    The early identification of young children's special educational needs (SEN), as well as the development of specific strategies to support those children identified with special needs, are increasingly recognised as crucial to facilitating good adjustment to school and to ensuring that such children are helped to reach their full potential in…

  19. Project International Emphasis Interim Report, July 1991.

    ERIC Educational Resources Information Center

    Blois, Beverly, Ed.; Williams, Barbara

    Project International Emphasis (PIE), a curriculum development effort involving all 24 colleges in the Virginia Community College System (VCCS), focuses on the infusion of globally oriented components across the academic curriculum and in related career development programs. Activities undertaken during the project's first year included an annual…

  20. Emphasis: Use and Misuse of Standardized Testing.

    ERIC Educational Resources Information Center

    Knudson, Richard L., Ed.

    1975-01-01

    Because of the active interest of English teachers in standardized tests and the increased use of such tests to measure student performance, the emphasis section of this issue of "The English Record" contains articles addressing this subject from several perspectives. A report of a survey on standardized testing in New York State sets the scene,…

  1. Emphasis upon Anthropo-Geography in Schools.

    ERIC Educational Resources Information Center

    Semple, Ellen Churchill

    1990-01-01

    Reprints a 1904 article from the "Journal of Geography" exploring geography's teaching focus. Argued for unchanged emphasis on the land and its people but advocated a deeper geographical interpretation of history. Contended that teaching should pay attention to scientific interpretation, and that children should discover a self-constructed…

  2. Acoustic Emphasis in Four Year Olds

    ERIC Educational Resources Information Center

    Wonnacott, Elizabeth; Watson, Duane G.

    2008-01-01

    Acoustic emphasis may convey a range of subtle discourse distinctions, yet little is known about how this complex ability develops in children. This paper presents a first investigation of the factors which influence the production of acoustic prominence in young children's spontaneous speech. In a production experiment, SVO sentences were…

  3. The Supervisor Emphasis Rating Form-Revised.

    ERIC Educational Resources Information Center

    Lanning, Wayne; Freeman, Brenda

    1994-01-01

    Discusses revision of Supervisor Emphasis Rating Form (SERF) into ipsative instrument and suggests future research that could profitably be done with new instrument. Explains rationale for choosing ipsative format and presents findings of study conducted to establish instrument reliability. SERF-Revised is appended. (Author/NB)

  4. Mobile Applications for Diabetics: A Systematic Review and Expert-Based Usability Evaluation Considering the Special Requirements of Diabetes Patients Age 50 Years or Older

    PubMed Central

    Quade, Mandy; Kirch, Wilhelm

    2014-01-01

    Background A multitude of mhealth (mobile health) apps have been developed in recent years to support effective self-management of patients with diabetes mellitus type 1 or 2. Objective We carried out a systematic review of all currently available diabetes apps for the operating systems iOS and Android. We considered the number of newly released diabetes apps, range of functions, target user groups, languages, acquisition costs, user ratings, available interfaces, and the connection between acquisition costs and user ratings. Additionally, we examined whether the available applications serve the special needs of diabetes patients aged 50 or older by performing an expert-based usability evaluation. Methods We identified relevant keywords, comparative categories, and their specifications. Subsequently, we performed the app review based on the information given in the Google Play Store, the Apple App Store, and the apps themselves. In addition, we carried out an expert-based usability evaluation based on a representative 10% sample of diabetes apps. Results In total, we analyzed 656 apps finding that 355 (54.1%) offered just one function and 348 (53.0%) provided a documentation function. The dominating app language was English (85.4%, 560/656), patients represented the main user group (96.0%, 630/656), and the analysis of the costs revealed a trend toward free apps (53.7%, 352/656). The median price of paid apps was €1.90. The average user rating was 3.6 stars (maximum 5). Our analyses indicated no clear differences in the user rating between free and paid apps. Only 30 (4.6%) of the 656 available diabetes apps offered an interface to a measurement device. We evaluated 66 apps within the usability evaluation. On average, apps were rated best regarding the criterion “comprehensibility” (4.0 out of 5.0), while showing a lack of “fault tolerance” (2.8 out of 5.0). Of the 66 apps, 48 (72.7%) offered the ability to read the screen content aloud. The number of

  5. Dying with Dignity: Difficult Times, Difficult Choices. A Report Presented by the Chairman of the Select Committee on Aging. House of Representatives, Ninety-Ninth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This report from the Select Committee on Aging examines financial, medical, and social issues surrounding terminally ill patients with special emphasis on the elderly terminally ill. The first section discusses topics related to the medical treatment of the terminally ill. Two basic issues are important: the right to have medical treatment and the…

  6. A study of the effects of cause specific death rates on age-specific death rates with special reference to Tamil Nadu.

    PubMed

    Navaneethan, K

    1983-10-01

    The objective of this study is to determine the effect of cause specific death rates on age specific death rates for Tamil Nadu rural females during the period 1970-75 in various age groups. 2 regression lines have been fitted. The age specific death rates were taken as dependent variables and time as an independent variable; the age-cause specific death rates were dependent variables and time was an independent variable. In the analysis, the ratio of regression coefficients of 2 regression lines gives the effect of age specific death rates due to the j-th cause in the i-th group. The trend of mortality in the age groups (0-4) and (5-14) declines over the period 1970-75 and increases in the age groups (15-34), (34-54) and 55 and older. The causes of declining mortality in the 0-4 age group are cough, fever, other clear symptoms and other causes. The %s of contribution for this decline are respectively 14%, 41%, 21% and 72% to the overall decline in that age group. The cause group violence and injury, digestive disorders and causes peculiar to infancy have contributed to increase in the 0-4 age group death rates. Digestive disorders, coughs and other causes have contributed to declining mortality in the 5-14 age group. The cause group accidents and injury, digestive disorders, other clear symptoms, child births and pregnancy and other causes are promoted to increase the mortality of the 15-34 age group. The causes contributing to the increasing trend of mortality in the 35-54 age group are violence and injury, digestive disorders, coughs, other clear symptoms, child births and pregnancy. Digestive disorders and other causes contributed to the mortality increase in the over 55 age group. PMID:12266915

  7. Leadership in Early Childhood Special Education

    ERIC Educational Resources Information Center

    Arora, Samita Berry

    2013-01-01

    With the demands of high quality early childhood special education programs within public school settings, there is a need to place emphasis on research and training regarding early childhood leaders and managers in this complex and diverse field. The focus of this research is to examine what early childhood special education (ECSE) leadership…

  8. Nutrition Management of School Age Children with Special Needs: A Resource Manual for School Personnel, Families, and Health Professionals. Second Edition.

    ERIC Educational Resources Information Center

    Horsley, Janet W.; Allen, Elizabeth R.; Daniel, Patricia White

    This guide is intended to help school personnel facilitate the management of special diets and nutrition education in the school curriculum in accordance with requirements of the National School Lunch Act, the Child Nutrition Act, the Rehabilitation Act of 1973 (Section 504), and the Americans with Disabilities Act of 1990. After the introduction,…

  9. Family Experiences with Accessing Information, Social and Resource Supports as Participants in Services for Their Special Needs Child over Three Years of Age

    ERIC Educational Resources Information Center

    Busillo-Aguayo, Joannie

    2010-01-01

    Families of children with special needs often experience substantial stress and an increased need for informational, social, or resource support throughout their child's growth and development. However, supports for families of children older than three often report a severe shortage of supports and difficulty accessing and utilizing them. Using…

  10. [The teaching of the biology of ageing in France 1990-2005: DEA with the course of speciality of Master Seeks].

    PubMed

    Courtois, Yves; Tréton, Jacques

    2006-03-01

    In 1990, following an idea arising from an Inserm study section on aging, the Diplôme d'études approfondies (DEA) de Biologie du vieillissement was created. Since then, more than 300 students have followed these courses which cover the cellular mechanisms of aging and associated diseases, from basic causes of aging to CNS and sensory organs aging, as well as nutritional aspects, sarcopenia and osteoporosis, vascular and neuroendocrine aging. More than 150 thesis have been defended and more than a quarter of students has been recruited on permanent positions in French universities and research institutions (10 %) and hospitals (16 %). Since its creation, one of the particularities of the DEA was the formal links between academia and industry since teaching takes place on private laboratory settings.

  11. The Relationship between Nutrition, Aging, and Health: A Personal and Social Challenge. Hearing before the Special Committee on Aging. United States Senate, Ninety-Ninth Congress, First Session (Albuquerque, New Mexico).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    This document presents witness testimonies and prepared statements from a Senate hearing called to examine the relationship between nutrition, aging, and health. An opening statement by Senator Jeff Bingaman is included. Jeffrey Blumberg, the acting associate director of the Human Nutrition Research Center on Aging, Tufts University, provides an…

  12. Thanatology Research from Quebec: A Different Emphasis.

    ERIC Educational Resources Information Center

    Mishara, Brian L.

    1993-01-01

    Notes that contributors to special journal issue have attempted to incorporate best aspects of European critical thinking within interdisciplinary and contextual approach, showing clear awareness of sociopolitical forces that affect one's relationship with mortality. Illustrates points by discussing Kurosawa film, "Ikuru," which recounts…

  13. Special Education. A Program Evaluation Report. Report #97-03.

    ERIC Educational Resources Information Center

    Minnesota State Office of the Legislative Auditor, St. Paul. Program Evaluation Div.

    This report presents findings of a state-wide evaluation of special education in Minnesota with emphasis on costs and the impact of state and federal regulations. Major findings indicated that the percentage of students receiving special education services has risen from 7.4 percent to 10.9 percent over the last two decades; special education…

  14. Special Education Programs & Services. [Bureau of Indian Affairs Guidelines].

    ERIC Educational Resources Information Center

    Bureau of Indian Affairs (Dept. of Interior), Albuquerque, NM.

    The Bureau of Indian Affairs (BIA) Guidelines for Special Education is a publication for use by educational personnel involved in special education. Emphasis is placed on the importance of preparing the exceptional child for the most useful future possible. Special education is seen as affording the exceptional child the opportunity to develop…

  15. Project SPECIAL TOPIC (Training of Professionals in Counseling).

    ERIC Educational Resources Information Center

    Brandell, Mary Ellen; And Others

    This paper describes Project SPECIAL TOPIC, which developed a preservice graduate training program at Central Michigan University for preparing related services personnel in the area of school counseling with special emphasis on special education needs. Two complete training cycles have been completed with a total of 22 full-time graduate students…

  16. Virtues and Well-Being of Korean Special Education Teachers

    ERIC Educational Resources Information Center

    Kim, So-Young; Lim, Young-Jin

    2016-01-01

    Although much emphasis has been paid to stress and burnout among special education teachers, little attention has been paid to their well-being. This study aimed to examine relations between virtues and well-being among Korean special education teachers. Virtues and well-being of 115 Korean special education teachers were assessed using the…

  17. The Spectator Role: Theoretical and Developmental Studies of Ideas about and Responses to Literature, with Special Reference to Four Age Levels.

    ERIC Educational Resources Information Center

    Applebee, Arthur Noble

    Theoretical aspects of the spectator role in James Britton's (1970) model of language use are explored within a perspective based primarily on the work of George Kelly, Susanne Langer, Jean Piaget, Michael Polanyi, and Denys Harding. This view is amplified in a series of empirical studies based on stories told by children between the ages of two…

  18. Demographic Aspects of Aging and the Older Population in the United States. Current Population Reports, Special Studies, Series P-23, No. 59.

    ERIC Educational Resources Information Center

    Siegel, Jacob S.; And Others

    This report presents a statistical portrait of the demographic aspects of aging and the older population in the Unites States. Most of the estimates are based on data from decennial censuses, the program of nonsurvey population estimates and projections carried out by the U.S. Bureau of the Census, the Current Population Survey, and other census…

  19. A Study of Words Relating to Youth and Old Age in the Plays of Euripides and Its Special Implications for Euripides'"Suppliant Women."

    ERIC Educational Resources Information Center

    Thury, Eva M.

    1988-01-01

    This study focuses on imagery of youth and old age in the plays of Euripides, especially the "Suppliant Women," considering frequently used words in each play according to formula developed by Pierre Guiraud. Identifies a motif, the rejuvenation theme, in several of Euripides' plays. Shows how the word "neos" (new, young) helps Euripides contrast…

  20. Special Needs.

    ERIC Educational Resources Information Center

    Braswell, Ray, Ed.

    This document contains the following papers on special needs instruction and technology: (1) "Hawaii Special Education Teacher Induction" (Kalena Oliva and Quinn Avery); (2) "The Impact of Group v Individual Use of Hypermedia-Based Instruction" (Lewis R. Johnson, Louis P. Semrau, and Gail E. Fitzgerald); (3) "Assistive Technology Meets…

  1. Sport Specialization, Part I

    PubMed Central

    Myer, Gregory D.; Jayanthi, Neeru; Difiori, John P.; Faigenbaum, Avery D.; Kiefer, Adam W.; Logerstedt, David; Micheli, Lyle J.

    2015-01-01

    Context: There is increased growth in sports participation across the globe. Sports specialization patterns, which include year-round training, participation on multiple teams of the same sport, and focused participation in a single sport at a young age, are at high levels. The need for this type of early specialized training in young athletes is currently under debate. Evidence Acquisition: Nonsystematic review. Study Design: Clinical review. Level of Evidence: Level 4. Conclusion: Sports specialization is defined as year-round training (greater than 8 months per year), choosing a single main sport, and/or quitting all other sports to focus on 1 sport. Specialized training in young athletes has risks of injury and burnout, while the degree of specialization is positively correlated with increased serious overuse injury risk. Risk factors for injury in young athletes who specialize in a single sport include year-round single-sport training, participation in more competition, decreased age-appropriate play, and involvement in individual sports that require the early development of technical skills. Adults involved in instruction of youth sports may also put young athletes at risk for injury by encouraging increased intensity in organized practices and competition rather than self-directed unstructured free play. Strength-of-Recommendation Taxonomy (SORT): C. PMID:26502420

  2. Online Learning. Special Report.

    ERIC Educational Resources Information Center

    Training, 1998

    1998-01-01

    Special section includes "World Wide Weeds" (Ann M. Bauer), about trainers as webmasters; "Get the Picture?" (Frank Jossi)--the role of digital video in computer-based training; and "The Reluctant Executive" (Anne K. Fredrickson), how to get administrators into the information age. (JOW)

  3. Special Education Guidelines.

    ERIC Educational Resources Information Center

    Bureau of Indian Affairs (Dept. of Interior), Albuquerque, NM.

    Provided are special education guidelines (revised 1974) for exceptional (handicapped or gifted) American Indian and Alaskan Native children from birth through age 25 years in schools operated by the Bureau of Indian Affairs (BIA). Reviewed are broad philosophical guidelines emphasizing individualized instruction, objectives such as decreasing…

  4. [Nuptiality in numbers (with emphasis on Puebla)].

    PubMed

    Bustillo Gomez, E

    1991-09-01

    In 1980, only 7.3% of Mexican women aged 50-54 and 6.7% of women the same age in the state of Puebla were single. The corresponding figures for men aged 50-54 were 5.3% in Mexico and 4.8% in Puebla. In 1980 the average ages at 1st marriage or union were 24.1 years in Mexico and 23.8 in Puebla for men and 21.6 years in Mexico and 21.4 in Puebla for women. Age at 1st marriage has not changed greatly since 1930, when it was estimated at 24.8 years for men and 21.5 for women. But some differentials are significant. In 1979, women residing in metropolitan areas married 2.2 years later on average than rural women. Women with high levels of education tend to marry at later ages. In 1980, 7.3% of unions in Mexico and 8.6% in Puebla were consensual. In Mexico in 1950 there were 44.7 divorces per 1000 marriages. In 1970 there were 87.3/1000 (many of which were divorces of foreigners occurring in Morelos and Chihuahua), in 1980 there were 44.9 and in 1986 there were 67.0. In puebla there were 14 divorces per 1000 marriages in 1950, 13.2 in 1970, 25.5 in 1980, and 43.6 in 1986. In 1980 about 1% of Mexicans aged 50-54 were divorced, compared to .7% in Puebla. In both Mexico and Puebla about 1% of men and 3.5% of women aged 50-54 were separated in 1980. Among individuals aged 50-54 in 1980, 3.4% of men in Mexico and 4% in Puebla were widowed, compared to 13.6% of women and 14% in Puebla. In 1991 some 45,000 persons in Puebla are expected to marry. PMID:12343348

  5. The Contribution of Phoneme-Grapheme Consistency and Cue Emphasis to Decoding in First-Graders.

    ERIC Educational Resources Information Center

    Vandever, Thomas R.

    The purposes of this study were to assess the effect of phoneme-grapheme consistency (PGC) and cue emphasis (CE) on the development of decoding skills in first graders and to determine the relationship of consistency of original lists to the recognition of new words. Subjects were 162 first graders, mean age 6.11 years and scoring above 30 on the…

  6. "Mother's child" and "father's child" among twins. A longitudinal twin study from pregnancy to 21 years age, with special reference to development and psychiatric disorders.

    PubMed

    Moilanen, I; Pennanen, P

    1997-01-01

    234 pairs of twins were studied from pregnancy up to 21 years of age on the basis of records from maternity hospitals, neonatal wards and children's health centres and questionnaires filled in by the parents when the twins were aged 2-10 and 12-21 years, and by the twins themselves at age 12-21. 74 twins were personally interviewed about human relationships in their families and with the Present State Examination (PSE) at age 15-21. When the evaluation of parental preference was made by the parents, the mother's favourites had learned to speak earlier and were more often the psychic leader of the pair, but they more often had sleeping difficulties and other psychosomatic symptoms in adolescence. They were most often scored in class 2-3, non-specific neurotic symptoms in the PSE, but none of them was placed in the higher classes of possible or probable psychiatric disorder. Mothers seem to develop a tighter affectionate bond towards their favourites than do fathers, thus inducing a good basic trust and faster language acquisition in childhood, but probably also transient non-specific neurotic symptoms in adolescence in face of the developmental task of entering autonomous adulthood. The father's favorites were more often the physical leaders of the pair, showed less accident proneness and most often reported tendencies towards autonomy from their co-twins, thus indicating that the fathers' attitudes may be more encouraging towards independence. As the least psychosomatic symptoms were seen in twins in the intermediate position regarding parental preference, it seems reasonable that the division of twins between parents on the grounds of favouritism should not be strict. PMID:9862010

  7. Genome instability, cancer and aging

    PubMed Central

    Maslov, Alexander Y.; Vijg, Jan

    2015-01-01

    DNA damage-driven genome instability underlies the diversity of life forms generated by the evolutionary process but is detrimental to the somatic cells of individual organisms. The cellular response to DNA damage can be roughly divided in two parts. First, when damage is severe, programmed cell death may occur or, alternatively, temporary or permanent cell cycle arrest. This protects against cancer but can have negative effects on the long term, e.g., by depleting stem cell reservoirs. Second, damage can be repaired through one or more of the many sophisticated genome maintenance pathways. However, erroneous DNA repair and incomplete restoration of chromatin after damage is resolved, produce mutations and epimutations, respectively, both of which have been shown to accumulate with age. An increased burden of mutations and/or epimutations in aged tissues increases cancer risk and adversely affects gene transcriptional regulation, leading to progressive decline in organ function. Cellular degeneration and uncontrolled cell proliferation are both major hallmarks of aging. Despite the fact that one seems to exclude the other, they both may be driven by a common mechanism. Here, we review age related changes in the mammalian genome and their possible functional consequences, with special emphasis on genome instability in stem/progenitor cells. PMID:19344750

  8. Lifelong Learning for an Aging Society. An Information Paper Prepared for Use by the Special Committee on Aging. United States Senate, 102d Congress, 1st Session. Committee Print.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    This report is an introduction to the concept of lifelong learning as a key to unlocking resources for an aging society. It describes a myriad of learning programs for older adults, from those provided by giant companies, to those conducted by small community centers, to those developed and run by elderly persons themselves. Programs are described…

  9. Aging and the Work Force: Human Resource Strategies. An Information Paper Prepared for Use by the Special Committee on Aging. United States Senate, Ninety-Seventh Congress, Second Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    This information paper explores the need for age-neutral functional criteria in the human resources management system and the need for managers to review currently accepted employment policies. Population patterns, labor force profiles, and labor force projections are reviewed. The paper examines the effect of retirement policies and considers…

  10. Special Delivery.

    ERIC Educational Resources Information Center

    Zimmer, Phil

    1986-01-01

    Specialized publications such as "Opera News,""Gourmet," and "Forbes" can bring an institution's story to targeted audiences. The experiences of Chautauqua Institution are described. Some of the benefits of marketing articles to these publications are discussed. (MLW)

  11. Brain Specialization Research and the Teaching of Nonverbal Communication.

    ERIC Educational Resources Information Center

    Jensen, Marvin D.

    1980-01-01

    The connectionist theory of brain functioning, which holds that specialization exists within the brain, has three implications for teachers of nonverbal communication. One implication involves the relative emphasis to be placed on linguistic/linear versus nonlinguistic/nonlinear mental processing. Teachers can shift emphasis to nonlinguistic…

  12. Are Special Education Students Happy?

    ERIC Educational Resources Information Center

    Uusitalo-Malmivaara, Lotta; Kankaanpaa, Paula; Makinen, Tuula; Raeluoto, Tiina; Rauttu, Karoliina; Tarhala, Veera; Lehto, Juhani E.

    2012-01-01

    This study compared the subjective and school-related happiness of 75 11- to 16-year-old special education students to 77 age- and gender-matched mainstream students using two quantitative measures. Additionally, the respondents chose from a list of 12 putative happy makers what they felt increased their happiness. Ten special education students…

  13. Postgraduation for Special Needs Students

    ERIC Educational Resources Information Center

    Schachter, Ron

    2012-01-01

    Special education occupies a large part of the mission--and budget--of many school districts. With learning disabilities such as ADHD and dyslexia each estimated to affect more than 10 percent of the school-age population, special education teachers have their hands full helping those students navigate increasingly rigorous, state-mandated…

  14. Special feature for the Olympics: effects of exercise on the immune system. Overview: exercise immunology.

    PubMed

    Gleeson, M

    2000-10-01

    The review articles in this special feature reflect the current status of knowledge in the field of exercise immunology, with a focus on how exercise affects the human immune system and the health implications for resistance to infections and neoplastic diseases. In an Olympic year, the emphasis of exercise immunology research tends to be on elite athletes and the prevention of infections in the quest for optimum performance. However, research presented in this issue also covers recreational athletes, as well as highlighting the benefits of exercise for our ageing population. PMID:11050530

  15. [Rotaviral diarrheas in children 0-14 years of age in Zyrardow district in period 2000-2002 with special reference to nosocomial infections].

    PubMed

    Korycka, Maria

    2006-01-01

    Dissertation is devoted to rotavirus infections in children 0-14 years of age hospitalized in the hospital of Zyrardów in 2000-2002. The first part of the work describes epidemiology of rotaviral infection in children, rotaviral vaccines and also presents data of rotaviral infections in the foreign and polish literature. The second part is concerning the data of rotaviral infection in children hospitalized in Zyrardów. Stool samples were examined in Bacteriological Laboratory of Powiatowa Stacja Sanitamo-Epidemiologiczna in Zyrardów for bacteria and for rotavirus by means of agglutination latex test Slidex Rota-Kit 2. All children with acute gastroenteritis rotaviral were hospitalized. The most of children were 0-4 years old. They had 89,1% of participation in the whole group of admitted children. In dissertation there were represented data in tables, concerning number of rotaviral diarrhea episodes in children 0-14 years with division into age groups, sex and urban-rural children, seasonality of infections and nosocomial rotaviral infections. The next part of the work is the anonymous survey containing five questions about social and family conditions of these children, which have fallen ill the rotaviral infection. The survey served to carry out the case-control research intending detection the risk factors for incidence of rotaviral infections in children. Conclusions of the survey: risk factors - sleeping with children in one room, more than three persons and improper sanitary conditions (lack of own bathroom in the apartment). PMID:17682758

  16. The environment of ageing.

    PubMed Central

    Tinker, A

    1997-01-01

    The issue of housing and the wider environment for an ageing population is one where there are many unanswered questions. In this paper a number of key issues are discussed and for each of these the focus is on three aspects. These are the current situation, its reasonableness and what research is needed in order to make decisions about policy and practice. The first three issues relate to the profile of older people themselves and the importance of home to them. The changing profile of older people is not just about an ageing population but also about the growing prominence of those with dementia, women, people from black and ethnic minority groups and one person households, yet little is known about the type of housing which should be provided. Of equal concern is the widening gap between those with a high standard of living (including housing) and those with a low standard of living. The importance of home to older people means that research must focus on how people can be enabled to remain there, and also on the costs, financial and otherwise, to carers and to society. The next three issues relate to the type of housing older people live in and moves in later life. The startling change in the tenure pattern with a growth of owner occupation brings problems as does the decline in social housing. The advantages and disadvantages of the different types of housing--mainstream and specialized--for older people are relatively well known. However the balance between the two needs more research as does that on retirement communities. While it is well known that there are peaks of migration in old age and that moves are often made in haste, little is known about the process of decision making. The final two topics concern links between housing and other aspects of older people's lives. On health more research is needed on temperature, mortality and morbidity, homelessness and accidents and especially on links between services. These topics have implications for planning

  17. The environment of ageing.

    PubMed

    Tinker, A

    1997-12-29

    The issue of housing and the wider environment for an ageing population is one where there are many unanswered questions. In this paper a number of key issues are discussed and for each of these the focus is on three aspects. These are the current situation, its reasonableness and what research is needed in order to make decisions about policy and practice. The first three issues relate to the profile of older people themselves and the importance of home to them. The changing profile of older people is not just about an ageing population but also about the growing prominence of those with dementia, women, people from black and ethnic minority groups and one person households, yet little is known about the type of housing which should be provided. Of equal concern is the widening gap between those with a high standard of living (including housing) and those with a low standard of living. The importance of home to older people means that research must focus on how people can be enabled to remain there, and also on the costs, financial and otherwise, to carers and to society. The next three issues relate to the type of housing older people live in and moves in later life. The startling change in the tenure pattern with a growth of owner occupation brings problems as does the decline in social housing. The advantages and disadvantages of the different types of housing--mainstream and specialized--for older people are relatively well known. However the balance between the two needs more research as does that on retirement communities. While it is well known that there are peaks of migration in old age and that moves are often made in haste, little is known about the process of decision making. The final two topics concern links between housing and other aspects of older people's lives. On health more research is needed on temperature, mortality and morbidity, homelessness and accidents and especially on links between services. These topics have implications for planning

  18. Sport skill level and gender with relation to age, physical development and special fitness of the participants of Olympic volleyball tournament Beijing 2008.

    PubMed

    Sterkowicz-Przybycien, Katarzyna; Sterkowicz, Stanislaw; Zak, Stanislaw

    2014-06-01

    The aim of this study was to provide an answer to the question whether and how age, body height, body mass, body mass index and results from fitness tests are related to sport skill level and gender of the participants of the Olympic volleyball tournament. Two-Way ANOVA was used to find the dependency of the variables on the factor of sport skill level (A--teams which took places 1 to 4, B--places from 5 to 8; C--places from 9 to 12) and gender (F--female; M--male). Statistical significance was set at p < 0.05. The Bonferroni's adjustment was carried out for three p = 0.017 and fifteen p = 0.003 pairs of comparisons). The M and F athletes included in A-C groups (N = 48 in each group) were than compared to the classification in the neural network of Probabilistic Neural Network (PNN). A combined effect of the factors of sports level and gender on the height of attack jump (F = 4.13; p = 0.02) and block jump (F = 9.22; p < 0.001) was identified. The level of achievement was modified by the differences between the men and women. A significant advantage over the groups B and C was found for attack height and block height. In the group A, the differences between the results obtained for women and men in the ranges of attack and block with respect to the net height were not significant. Mean range of block jump did not match up to attack jump, particularly in women. The application of PNN network showed that age, BMI, relative attack jump and block jump are good predictors of sport results. The percentage of properly classified players in the group of men was lower than in women (42.4 vs. 56.3%). In this regard, big differences were found at the lower level of sport results: A (77.1 vs. 79.2%), B (25.0 vs. 25.0%) and C (25.0 vs. 64.6%). In conclusion, selection for national teams should take into consideration the players with long competitive experience with adequate weight/height ratios, who exhibit good training adaptations to jumping exercise.

  19. Sport skill level and gender with relation to age, physical development and special fitness of the participants of Olympic volleyball tournament Beijing 2008.

    PubMed

    Sterkowicz-Przybycien, Katarzyna; Sterkowicz, Stanislaw; Zak, Stanislaw

    2014-06-01

    The aim of this study was to provide an answer to the question whether and how age, body height, body mass, body mass index and results from fitness tests are related to sport skill level and gender of the participants of the Olympic volleyball tournament. Two-Way ANOVA was used to find the dependency of the variables on the factor of sport skill level (A--teams which took places 1 to 4, B--places from 5 to 8; C--places from 9 to 12) and gender (F--female; M--male). Statistical significance was set at p < 0.05. The Bonferroni's adjustment was carried out for three p = 0.017 and fifteen p = 0.003 pairs of comparisons). The M and F athletes included in A-C groups (N = 48 in each group) were than compared to the classification in the neural network of Probabilistic Neural Network (PNN). A combined effect of the factors of sports level and gender on the height of attack jump (F = 4.13; p = 0.02) and block jump (F = 9.22; p < 0.001) was identified. The level of achievement was modified by the differences between the men and women. A significant advantage over the groups B and C was found for attack height and block height. In the group A, the differences between the results obtained for women and men in the ranges of attack and block with respect to the net height were not significant. Mean range of block jump did not match up to attack jump, particularly in women. The application of PNN network showed that age, BMI, relative attack jump and block jump are good predictors of sport results. The percentage of properly classified players in the group of men was lower than in women (42.4 vs. 56.3%). In this regard, big differences were found at the lower level of sport results: A (77.1 vs. 79.2%), B (25.0 vs. 25.0%) and C (25.0 vs. 64.6%). In conclusion, selection for national teams should take into consideration the players with long competitive experience with adequate weight/height ratios, who exhibit good training adaptations to jumping exercise. PMID:25144981

  20. The aging skin.

    PubMed

    Bergfeld, W F

    1997-01-01

    In the past, sun exposure has been an integral part of the American life style. Along with increased leisure time, outdoor recreational sports, and sun bathing has come greater exposure to the sun. The cumulative effects of unprotected sun exposure coupled with the changes in the ozone layer have resulted in a large photodamaged population and an epidemic of the most dangerous skin cancer, malignant melanoma. Photodamage begins early, with a child's first unprotected sun exposure. Clinical studies show that 50% of an individual's ultraviolet light exposure occurs before the age of 18 years. This damage from acute and chronic ultraviolet light exposure has produced the explosion of skin cancers. Over the next 4 years, it is expected that skin cancer will become the most common type of cancer, and malignant melanoma will become the leading cause of death from skin cancer. This growing hazard to the public has profound medical and psychological ramifications. This paper will focus on prevention, identification, evaluation and treatment of photodamage to skin, as well as skin cancer. Special emphasis will be given to the National Skin Cancer Prevention Education Program.

  1. Aging and Cerebral Palsy.

    ERIC Educational Resources Information Center

    Networker, 1993

    1993-01-01

    This special edition of "The Networker" contains several articles focusing on aging and cerebral palsy (CP). "Aging and Cerebral Palsy: Pathways to Successful Aging" (Jenny C. Overeynder) reports on the National Invitational Colloquium on Aging and Cerebral Palsy held in April 1993. "Observations from an Observer" (Kathleen K. Barrett) describes…

  2. Special Advocate.

    ERIC Educational Resources Information Center

    Vander Weele, Maribeth

    1992-01-01

    Thomas Hehir, special education chief of Chicago Public Schools, is evangelist of integrating children with disabilities into regular classrooms. By completely reorganizing department viewed as political patronage dumping ground, Hehir has made remarkable progress in handling large number of children awaiting evaluation and placement in special…

  3. Developments in Aging: 1984. Volume 1. A Report of the Special Committee on Aging. United States Senate, Ninety-Ninth Congress, First Session. Pursuant to S. Res. 354, March 2, 1984, Resolution Authorizing a Study of the Problems of the Aged and Aging.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    This is a 1984 annual Senate report on aging which examines the health, income, employment, housing, and assistance problems of older people. In a preface, Senators Heinz and Glenn note the following significant events of l984: (1) Congress reauthorized the Older Americans Act; (2) a strong economy with low inflation helped Social Security and…

  4. 76 FR 12361 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Determine of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-07

    ... Respiratory Illness in Decreasing Influenza Transmission, Funding Opportunity Number (FOA) CK11-007, Initial... applications received in response to ``Determine of the Benefits of work and/or School Exclusion to...

  5. 77 FR 14806 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-13

    ..., Prevention and Treatment of Influenza and Other Respiratory Infections in Ghana, Studies at the Animal-Human... Influenza and Other Respiratory Infections in the United States, and Epidemiology, Prevention and Treatment of Influenza and Other Respiratory Infections in Panama and Central America Region,...

  6. 77 FR 4047 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-26

    ..., Prevention and Treatment of Influenza and Other Respiratory Infections in Ghana, IP12- 001, Studies at the... Community Associated Influenza and Other Respiratory Infections in the United States, IP12-003, and Epidemiology, Prevention and Treatment of Influenza and Other Respiratory Infections in Panama and...

  7. Computed tomography of the orbit with special emphasis on coronal sections: Part II. Pathological anatomy.

    PubMed

    Tadmor, R; New, P F

    1978-01-01

    Visualization of orbital soft tissue structures by computed tomography in direct coronal and axial studies is extremely useful in diagnosis. Direct enlargement viewing of scans has disclosed minute anatomical details. This study reviews some of our experiences in the investigation of a variety of lesions within the orbit and attempts, in particular, to illustrate the value of direct coronal studies.

  8. 76 FR 18766 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-05

    ... Research and Surveillance in Epilepsy, Funding Opportunity Announcement (FOA) DP11- 003, initial review. In... received in response to ``Epidemiologic Research and Surveillance in Epilepsy FOA DP11-003, initial...

  9. 78 FR 6329 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-30

    ... Study to Evaluate Pregnancy exposureS (BD-STEPS), FOA DD13-003, initial review. In accordance with... received in response to ``Birth Defects Study to Evaluate Pregnancy exposureS (BD-STEPS), FOA...

  10. 76 FR 3908 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-21

    ... Officer, CDC, National Center for Chronic Disease Prevention and Health Promotion, Office of the Director... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and.... L. 92-463), the Centers for Disease Control and Prevention (CDC) announces the...

  11. 75 FR 77645 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pregnancy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-13

    ... Center for Chronic Disease Prevention and Health Promotion, Office of the Director, Extramural Research... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and.... 92-463), the Centers for Disease Control and Prevention (CDC) announces the aforementioned...

  12. 76 FR 13414 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pilot...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-11

    ... Blackman, Ph.D., Scientific Review Officer, CDC, National Center for Chronic Disease Prevention and Health... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... Disease Control and Prevention and the Agency for Toxic Substances and Disease Registry. Dated: March...

  13. 75 FR 13769 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Natural...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-23

    ... More Information: Donald Blackman, PhD., Scientific Review Officer, National Center for Chronic Disease... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... Committee Act (Pub. L. 92-463), the Centers for Disease Control and Prevention (CDC) announces...

  14. 76 FR 12122 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-04

    ...., Scientific Review Officer, CDC, National Center for Chronic Disease Prevention and Health Promotion, Office... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... announcements of meetings and other committee management activities, for both the Centers for Disease...

  15. 75 FR 29561 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Surveillance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-26

    ... Information: Donald Blackman, Ph.D., Scientific Review Officer, National Center for Chronic Disease Prevention... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... Agency for Toxic Substances and Disease Registry. Dated: May 20, 2010. Andre Tyler, Acting...

  16. 76 FR 49771 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-11

    ..., National Center for Chronic Disease Prevention and Health Promotion, CDC, 4770 Buford Highway, NE... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... Advisory Committee Act (Pub. L. 92-463), the Centers for Disease Control and Prevention (CDC) announces...

  17. 75 FR 18848 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Prevention...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-13

    ..., PhD, Scientific Review Officer, National Center for Chronic Disease Prevention and Health Promotion... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... Act (Pub. L. 92-463), the Centers for Disease Control and Prevention (CDC) announces...

  18. 78 FR 17412 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-21

    ... the Monitoring and Evaluation of Programs for the Elimination and Control of Neglected Tropical... review, discussion, and evaluation of applications received in response to ``Strengthening the Monitoring and Evaluation of Programs for the Elimination and Control of Neglected Tropical Diseases in...

  19. 78 FR 66938 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ... ``Capacity Assistance for High Impact HIV Prevention'', Funding Opportunity Announcement PS14-1403, initial review, published in the Federal Register on September 18, 2013 (FR Volume 78, Number 181, Page 57391... meeting is rescheduled in accordance with section 10(a)(2) of the Federal Advisory Committee Act (Pub....

  20. 77 FR 25181 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-27

    ..., Cholera And HIV/AIDS Response, GH12-003, initial review. In accordance with Section 10(a)(2) of the... Assistance To The Ministry Of Public Health Of Haiti To Support Post Earthquake Reconstruction, Cholera...

  1. 76 FR 78263 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-16

    ... Safety and Health Training Project Grants, Program Announcement PAR 10-288, initial review. In accordance... set forth in Section 552b(c)(4) and (6), Title 5 U.S.C., and the Determination of the Director... to ``Occupational Safety and Health Training Project Grants, PAR 10-288.'' Contact Person for...

  2. Environmental pollutants in the Swedish marine ecosystem, with special emphasis on polybrominated diphenyl ethers (PBDE).

    PubMed

    Carlsson, Pernilla; Herzke, Dorte; Wedborg, Margareta; Gabrielsen, Geir Wing

    2011-02-01

    Levels of polybrominated diphenyl ethers (PBDEs), polybrominated biphenyls (PBBs), polychlorinated biphenyls (PCBs), dichlorodiphenyltrichloroethane (DDT) and perfluorinated organic compounds (PFCs) were analysed in whole herring (Clupea harengus) and sprat (Sprattus sprattus), eggs from common eider (Somateria mollissima) and eggs and livers from herring gull (Larus argentatus) from the Swedish west coast. The contaminant values obtained were compared with published values from the Arctic marine ecosystem. Tetra- and penta-brominated PBDEs were detected at low levels in herring, sprat and common eider (ΣPBDE 0.3-2.0 ng g(-1) ww), while the levels were higher in the herring gull samples (ΣPBDE 1.3-29.9 ng g(-1) ww). Hexa-decaBDEs were also found in samples from herring gulls. Eggs from herring gulls from the sub-Arctic contained four times more PBDE than the Swedish herring gulls eggs. Fish samples from the Arctic had two times higher levels of PBDEs and DDTs than similar samples from Sweden. The higher levels of contaminants in fish and seabirds from the Arctic reflect differences in transport processes, feeding ecology (reflected by trophic levels) and metabolism. PBDEs contributed to <10% of the total contaminant load in all investigated samples. The relative contribution of DDTs was higher in fish and bird samples from the Arctic when compared to Swedish samples, e.g. 65% in glaucous gull livers compared to 10% in herring gull livers. This study shows that even though the Swedish west coast is more urban than the Arctic, higher pollutants levels are found in seabird species from the Arctic. PMID:21220151

  3. 76 FR 9785 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Human...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-22

    ... of Color Who Have Sex With Men and Young Transgender Persons of Color, Funding Opportunity... Projects for Young Men ] of Color Who Have Sex with Men and Young Transgender Persons of Color, FOA...

  4. 78 FR 9055 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-07

    ... Healthcare Practitioner Capacity Around HPV Vaccine Communication, Funding Opportunity Announcement (FOA... Capacity around HPV Vaccine Communication, FOA IP13-001''. Contact Person For More Information:...

  5. Bioactivity of cinnamon with special emphasis on diabetes mellitus: a review.

    PubMed

    Bandara, Thushari; Uluwaduge, Inoka; Jansz, E R

    2012-05-01

    Cinnamon is the oldest spice and has been used by several cultural practices for centuries. In addition to its culinary uses, cinnamon possesses a rising popularity due to many stated health benefits. Out of the large number of cinnamon species available, Cinnamomum aromaticum (Cassia) and Cinnamomum zeylanicum have been subjected to extensive research. Available in vitro and in vivo evidence indicates that cinnamon may have multiple health benefits, mainly in relation to hypoglycaemic activity. Furthermore, the therapeutic potential of cinnamon is stated also to be brought about by its anti-microbial, anti-fungal, antiviral, antioxidant, anti-tumour, blood pressure-lowering, cholesterol and lipid-lowering and gastro-protective properties. This article provides a summary of the scientific literature available on both C. aromaticum and C. zeylanicum. All studies reported here have used cinnamon bark and its products. Although almost all the animal models have indicated a pronounced anti-diabetic activity of both cinnamon species, conflicting results were observed with regard to the few clinical trials available. Therefore, the necessity of evaluating the effects of cinnamon for its therapeutic potential through well-defined and adequately powered randomized controlled clinical trials is emphasized, before recommendations are made for the use of cinnamon as an effective treatment for humans.

  6. 78 FR 19490 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-01

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... and Prevention and the Agency for Toxic Substances and Disease Registry. Dana Redford, Acting Director, Management Analysis and Services Office, Centers for Disease Control and Prevention. BILLING CODE 4163-18-P...

  7. 77 FR 22326 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-13

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... Disease Control and Prevention (CDC) announces the aforementioned meeting: Time and Date: 1 p.m.-2 p.m... meetings and other committee management activities, for both the Centers for Disease Control and...

  8. 78 FR 56236 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-12

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... Committee Act (Pub. L. 92-463), the Centers for Disease Control and Prevention (CDC) announces the... Disease Control and Prevention and the Agency for Toxic Substances and Disease Registry. Elaine L....

  9. 78 FR 19489 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-01

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... the Federal Advisory Committee Act (Pub. L. 92-463), the Centers for Disease Control and Prevention... activities, for both the Centers for Disease Control and Prevention and the Agency for Toxic Substances...

  10. 77 FR 36544 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-19

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... Committee Act (Pub. L. 92-463), the Centers for Disease Control and Prevention (CDC) announces the... management activities, for both the Centers for Disease Control and Prevention and the Agency for...

  11. 77 FR 7164 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-10

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... Federal Advisory Committee Act (Pub. L. 92-463), the Centers for Disease Control and Prevention (CDC... committee management activities, for both the Centers for Disease Control and Prevention, and the Agency...

  12. 78 FR 19490 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panels (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-01

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... activities, for both the Centers for Disease Control and Prevention and the Agency for Toxic Substances and... Disease Control and Prevention. BILLING CODE 4163-18-P...

  13. 78 FR 25743 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-02

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... Federal Advisory Committee Act (Pub. L. 92-463), the Centers for Disease Control and Prevention (CDC... both the Centers for Disease Control and Prevention and the Agency for Toxic Substances and...

  14. 77 FR 20822 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-06

    ... Person for More Information: Jane Suen, Dr.P.H., M.S., Scientific Review Officer, CDC, 4770 Buford... aforementioned meeting: Time and Date: 12 p.m.-3 p.m., April 26, 2012 (Closed). Place: Teleconference....

  15. 78 FR 23768 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-22

    ... Research Capacity to Assess Health Effects Associated with Volcanic Emissions and other Environmental... to ``Developing Research Capacity to Assess Health Effects Associated with Volcanic Emissions and... committee management activities, for both the Centers for Disease Control and Prevention and the Agency...

  16. 76 FR 24031 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-29

    ... Improve Vaccination Coverage of Children in Child Care Centers (CCCs) and Preschools, Funding Opportunity... Information Systems, FOA IP11-008; and Effectiveness in an Intervention to Promote a Targeted Vaccination... to ``Strategies to Improve Vaccination Coverage of Children in Child Care Centers (CCCs)...

  17. 76 FR 33304 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... Improve Vaccination Coverage of Children in Child Care Centers (CCCs) and Preschools, Funding Opportunity... Information Systems, FOA IP11-008; Effectiveness in an Intervention to Promote a Targeted Vaccination...

  18. 78 FR 52535 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-23

    ... Japanese Encephalitis Vaccination in Cambodia, Funding Opportunity Announcement (FOA) CK14-001, initial... evaluation of applications received in response to ``Impact of Japanese Encephalitis Vaccination in...

  19. 76 FR 28438 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... Care Act (ACA): Childhood Obesity Research Funding Opportunity Announcement (FOA) DP11- 007, Panel B... evaluation of ``Affordable Care Act (ACA): Childhood Obesity Research Funding Opportunity Announcement...

  20. Nuclear microscopy in biomedical analysis with special emphasis on clinical metal biology

    NASA Astrophysics Data System (ADS)

    Lindh, Ulf; Frisk, Peter; Nyström, Joakim; Danersund, Antero; Hudecek, Romuald; Lindvall, Anders; Thunell, Stig

    1997-07-01

    Nuclear microscopy based upon developments in high energy ion beam techniques is by now an accepted technique in many fields of research. The advancements into the biomedical field have, however, been slower than expected. A major factor explaining this tendency is the availability of nuclear microscopy. This paper reviews briefly the biomedical work using nuclear microscopy that has been carried out since the 4 th International Conference on Nuclear Microprobe Technology and Applications held in Shanghai. Nuclear microscopy of isolated individual blood cells from patients adversely affected by metal exposure from dental amalgam has been performed both before and after removal of the metallic fillings. The elemental profile of blood cells was more or less normalised after treatment. Some of these results will be presented to illustrate a medical application. Results from bulk analysis by ICP-MS of erythrocytes and plasma before and after treatment will also be presented to illustrate the difference in information content between these two approaches as well as the need for complementary information in solving biomedical problems. As part of a larger study of acute porphyria, nuclear microscopy of blood cells was included among the 78 laboratory tests. The approach in this study was unbiased in the sense that no hypothesis was formulated as to which laboratory parameters would be the most explanatory for health or disease. Multivariate discriminant analysis was applied to the large amounts of data acquired. This approach led to the hypothesis that oxidative stress increased the synthesis of manganese-dependent superoxide dismutase in the mitochondria of polymorphonuclear leukocytes, explaining the increase of manganese in these cells. Antioxidant therapy was therefore applied to a couple of patients with porphyria, however, without clinical success.

  1. 76 FR 27327 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Virologic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-11

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... Among Humans, Funding Opportunity Announcement, IP11-001 Correction: The notice was published in the... both the Centers for Disease Control and Prevention and the Agency for Toxic Substances and...

  2. 77 FR 73662 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-11

    ... Safety and Health Education and Research Centers (ERC) PAR 10-217, initial review. In accordance with... in response to ``Occupational Safety and Health Education and Research Centers (ERC) PAR 10-217... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH...

  3. 77 FR 19018 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-29

    ... Public Health Research in South Africa, Funding Opportunity Announcement (FOA) GH12- 004, initial review... applications received in response to ``Conducting Public Health Research in South Africa, FOA...

  4. 77 FR 3269 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Data...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-23

    ... [Federal Register Volume 77, Number 14 (Monday, January 23, 2012)] [Notices] [Page 3269] [FR Doc... Services Office, Centers for Disease Control and Prevention. [FR Doc. 2012-1191 Filed 1-20-12; 8:45 am... Coordinating Center for Autism and Other Developmental Disabilities Research and Epidemiologic Studies,...

  5. Effects of global warming on fish reproductive endocrine axis, with special emphasis in pejerrey Odontesthes bonariensis.

    PubMed

    Miranda, Leandro Andrés; Chalde, Tomás; Elisio, Mariano; Strüssmann, Carlos Augusto

    2013-10-01

    The ongoing of global warming trend has led to an increase in temperature of several water bodies. Reproduction in fish, compared with other physiological processes, only occurs in a bounded temperature range; therefore, small changes in water temperature could significantly affect this process. This review provides evidence that fish reproduction may be directly affected by further global warming and that abnormal high water temperature impairs the expression of important genes throughout the brain-pituitary-gonad axis. In all fishes studied, gonads seem to be the organ more readily damaged by heat treatments through the inhibition of the gene expression and subsequent synthesis of different gonadal steroidogenic enzymes. In view of the feedback role of sex steroids upon the synthesis and release of GnRH and GtHs in fish, it is possible that the inhibition observed at brain and pituitary levels in treated fish is consequence of the sharp decrease in plasma steroids levels. Results of in vitro studies on the inhibition of pejerrey gonad aromatase expression by high temperature corroborate that ovary functions are directly disrupted by high temperature independently of the brain-pituitary axis. For the reproductive responses obtained in laboratory fish studies, it is plausible to predict changes in the timing and magnitude of reproductive activity or even the total failure of spawning season may occur in warm years, reducing annual reproductive output and affecting future populations.

  6. 76 FR 29756 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-23

    ... Agricultural Disease and Injury Research, Education, and Prevention, Program Announcement (PA) Number PAR-11... Agricultural Disease and Injury Research, Education, and Prevention, PAR-11-022, initial review.'' Contact... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention...

  7. 77 FR 39497 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-03

    ... Project (SIP): Evaluation of School Salad Bars as a Public Health Intervention to Increase Fruit and... in response to ``Evaluation of School Salad Bars as a Public Health Intervention to Increase...

  8. Proper housing conditions in experimental stroke studies-special emphasis on environmental enrichment.

    PubMed

    Mering, Satu; Jolkkonen, Jukka

    2015-01-01

    Environmental enrichment provides laboratory animals with novelty and extra space, allowing different forms of multisensory stimulation ranging from social grouping to enhanced motor activity. At the extreme end of the spectrum, one can have a super-enriched environment. Environmental enrichment is believed to result in improved cognitive and sensorimotor functions both in naïve rodents and in animals with brain lesions such as those occurring after a stroke. Robust behavioral effects in animals which have suffered a stroke are probably related not only to neuronal plasticity in the perilesional cortex but also in remote brain areas. There is emerging evidence to suggest that testing restorative therapies in an enriched environment can maximize treatment effects, e.g., the perilesional milieu seems to be more receptive to concomitant pharmacotherapy and/or cell therapy. This review provides an updated overview on the effect of an enriched environment in stroke animals from the practical points to be considered when planning experiments to the mechanisms explaining why combined therapies can contribute to behavioral improvement in a synergistic manner.

  9. 77 FR 25180 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-27

    ... Research on Moderate Acute Malnutrition in Humanitarian Emergencies, Funding Opportunity Announcement (FOA... Malnutrition in Humanitarian Emergencies, FOA GH12-006, initial review.'' Contact Person for More...

  10. Histology, Immunohistochemistry and Ultrastructure of the Bovine Palatine Tonsil with Special Emphasis on Reticular Epithelium

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The paired palatine tonsils are located at the junction of the nasopharynx and oropharynx; ideally positioned to sample antigens entering through either the nasal cavity or oral cavity. Entering antigens will first contact tonsilar epithelium. To better understand the cellular and functional composi...

  11. 78 FR 9926 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-12

    ... Incentive- based Smoking Cessation for Pregnant Women, FOA DP 13-003, initial review. In accordance with... applications received in response to ``Cost-Benefit of Incentive-based Smoking Cessation for Pregnant...

  12. Culture, Gender and Education in Rural Development with Special Emphasis on Ethiopia.

    ERIC Educational Resources Information Center

    Negussie, Birgit

    In this address, statistical data from the Ethiopian National Census (1984) and a brief account of the development of the nation from feudal rule to democratic republic are followed by a discussion of characteristics of the modern Ethiopian state. Particular attention is given to the administrative apparatus, multiethnic composition, sociocultural…

  13. Yeasts in malting, with special emphasis on Wickerhamomyces anomalus (synonym Pichia anomala).

    PubMed

    Laitila, Arja; Sarlin, Tuija; Raulio, Mari; Wilhelmson, Annika; Kotaviita, Erja; Huttunen, Timo; Juvonen, Riikka

    2011-01-01

    Malted barley is a major raw material of beer, as well as distilled spirits and several food products. The production of malt (malting) exploits the biochemical reactions of a natural process, grain germination. In addition to germinating grain, the malting process includes another metabolically active component: a diverse microbial community that includes various types of bacteria and fungi. Therefore, malting can be considered as a complex ecosystem involving two metabolically active groups. Yeasts and yeast-like fungi are an important part of this ecosystem, but previously the significance of yeasts in malting has been largely underestimated. Characterization and identification of yeasts in industrial processes revealed 25 ascomycetous yeasts belonging to 10 genera, and 18 basidiomycetous yeasts belonging to 7 genera. In addition, two ascomycetous yeast-like fungi belonging to the genera Aureobasidium and Exophiala were commonly detected. Yeasts and yeast-like fungi produced extracellular hydrolytic enzymes with a potentially positive contribution to the malt enzyme spectrum. Several ascomycetous yeast strains showed strong antagonistic activity against field and storage moulds, Wickerhamomyces anomalus (synonym Pichia anomala) being the most effective species. Malting studies revealed that W. anomalus VTT C-04565 effectively restricted Fusarium growth and hydrophobin production during malting and prevented beer gushing. In order to broaden the antimicrobial spectrum and to improve malt brewhouse performance, W. anomalus could be combined with other starter cultures such as Lactobacillus plantarum. Well-characterized microbial mixtures consisting of barley and malt-derived microbes open up several possibilities to improve malt properties and to ensure the safety of the malting process. PMID:20872177

  14. Cold Shock Proteins: A Minireview with Special Emphasis on Csp-family of Enteropathogenic Yersinia

    PubMed Central

    Keto-Timonen, Riikka; Hietala, Nina; Palonen, Eveliina; Hakakorpi, Anna; Lindström, Miia; Korkeala, Hannu

    2016-01-01

    Bacteria have evolved a number of mechanisms for coping with stress and adapting to changing environmental conditions. Many bacteria produce small cold shock proteins (Csp) as a response to rapid temperature downshift (cold shock). During cold shock, the cell membrane fluidity and enzyme activity decrease, and the efficiency of transcription and translation is reduced due to stabilization of nucleic acid secondary structures. Moreover, protein folding is inefficient and ribosome function is hampered. Csps are thought to counteract these harmful effects by serving as nucleic acid chaperons that may prevent the formation of secondary structures in mRNA at low temperature and thus facilitate the initiation of translation. However, some Csps are non-cold inducible and they are reported to be involved in various cellular processes to promote normal growth and stress adaptation responses. Csps have been shown to contribute to osmotic, oxidative, starvation, pH and ethanol stress tolerance as well as to host cell invasion. Therefore, Csps seem to have a wider role in stress tolerance of bacteria than previously assumed. Yersinia enterocolitica and Yersinia pseudotuberculosis are enteropathogens that can spread through foodstuffs and cause an enteric infection called yersiniosis. Enteropathogenic Yersinia are psychrotrophs that are able to grow at temperatures close to 0°C and thus they set great challenges for the modern food industry. To be able to efficiently control psychrotrophic Yersinia during food production and storage, it is essential to understand the functions and roles of Csps in stress response of enteropathogenic Yersinia. PMID:27499753

  15. 78 FR 17411 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-21

    ... Evaluation of Malaria Control and Elimination Activities, FOA GH13-005, initial review. In accordance with... in response to ``Monitoring and Evaluation of Malaria Control and Elimination Activities, FOA...

  16. 78 FR 78966 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ..., Prevention, and Treatment of Influenza and Other Respiratory Infections in a Malaria- Endemic Area of Malawi... Respiratory Infections in a Malaria-Endemic Area of Malawi with High HIV Prevalence, FOA IP14-002''....

  17. 78 FR 9926 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-12

    ... Incidence of Inflammatory Bowel Disease, FOA DP 13-001, initial review. In accordance with Section 10(a)(2... to ``Prevalence and Incidence of Inflammatory Bowel Disease, FOA DP 13-001, initial review.'' Contact... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention...

  18. Environmental Effects on Health with Special Emphasis on Neurotoxicology. Matrix No. 16.

    ERIC Educational Resources Information Center

    Uphouse, Lynda L.

    Environmental influences can significantly affect (both positively and negatively) the developing child. Three ways in which the environment affects the developing organism are induction, facilitation, and maintenance. In the case of induction the presence or absence of specific stimuli totally determines whether or not a particular developmental…

  19. Chemistry in confining reaction fields with special emphasis on nanoporous materials.

    PubMed

    Polarz, Sebastian; Kuschel, Andreas

    2008-01-01

    The everyday routine of most chemists is dictated by large numbers. The chemical rules for ensembles of molar size (N approximately N(A)=6.022 x 10(23)) are well known and can be understood in most cases by using Boltzmann distribution. It is an interesting question how a small ensemble of a chemical system behaves and if it differs from the respective large-ensemble counterpart. The experimental approach presented in the current paper involves the division of a macroscopic volume into compartments that contain only a small number of reactants. The compartments represent the pores of tailor-made nanoporous materials.

  20. 77 FR 39497 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-03

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... Projects (SIPs): Nutrition and Obesity Policy Research and Evaluation Network (NOPREN)--Coordinating Center, SIP12-061 and Nutrition and Obesity Policy Research and Evaluation Network...

  1. 77 FR 5026 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ... Reasons for Racial/Ethnic Disparities with Completing the HPV Vaccine Series among Adolescent Females... for Racial/Ethnic Disparities with Completing the HPV Vaccine Series among Adolescent Females,...

  2. The excitability of plant cells: with a special emphasis on characean internodal cells

    NASA Technical Reports Server (NTRS)

    Wayne, R.

    1994-01-01

    This review describes the basic principles of electrophysiology using the generation of an action potential in characean internodal cells as a pedagogical tool. Electrophysiology has proven to be a powerful tool in understanding animal physiology and development, yet it has been virtually neglected in the study of plant physiology and development. This review is, in essence, a written account of my personal journey over the past five years to understand the basic principles of electrophysiology so that I can apply them to the study of plant physiology and development. My formal background is in classical botany and cell biology. I have learned electrophysiology by reading many books on physics written for the lay person and by talking informally with many patient biophysicists. I have written this review for the botanist who is unfamiliar with the basics of membrane biology but would like to know that she or he can become familiar with the latest information without much effort. I also wrote it for the neurophysiologist who is proficient in membrane biology but knows little about plant biology (but may want to teach one lecture on "plant action potentials"). And lastly, I wrote this for people interested in the history of science and how the studies of electrical and chemical communication in physiology and development progressed in the botanical and zoological disciplines.

  3. Managing Chronic Pain in Special Populations with Emphasis on Pediatric, Geriatric, and Drug Abuser Populations.

    PubMed

    Baumbauer, Kyle M; Young, Erin E; Starkweather, Angela R; Guite, Jessica W; Russell, Beth S; Manworren, Renee C B

    2016-01-01

    In the adult population chronic pain can lead to loss of productivity and earning potential, and decreased quality of life. There are distinct groups with increased vulnerability for the emergence of chronic pain. These groups may be defined by developmental status and/or life circumstances. Within the pediatric, geriatric, and drug abuser populations, chronic pain represents a significant health issue. This article focuses on known anatomic, physiologic, and genetic mechanisms underlying chronic pain in these populations, and highlights the need for a multimodal approach from multiple health care professionals for management of chronic pain in those with the most risk.

  4. Recent Advances in Ocular Drug Delivery, with Special Emphasis on Lipid Based Nanocarriers.

    PubMed

    Sah, Abhishek K; Suresh, Preeti K

    2015-01-01

    Eye is a vital sense organ of our body and any disorder can lead to serious medical implications that may put great financial burden on patient and their family. Effective drug delivery to the eye is a challenging proposition for the pharmaceutical scientist. Eye drops have been globally accepted as a formulation for anterior segment applications. On one hand it is widely used owing to its convenience but is also associated with some limitations in terms of desired pharmacological and pharmacokinetic profile, dosing frequency, systemic untoward effects, patient noncompliance, low drug bioavailability due to transient contact time, rapid washout by tearing and nasolacrimal drainage. The need to overcome these major issues related to ocular pharmacotherapy has been long recognized. Several novel nanocarriers including nanolipid based carrier systems have been widely explored and investigated for ophthalmic applications. These include solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC), liposomes, in situ gels, niosomes, mucoadhesive systems and discomes. Since lipids have similar structure to human cell lipids, their biodegradable, non-toxic and biocompatible profile are particularly useful. Additionally, they also offer protection against drug degradation, impart controlled drug release characteristics and site specific delivery. This review explores the potential feasibility of lipid component in formulation of nanomedicine for ophthalmic delivery and reports the clinical findings in order to improve the ocular pharmacotherapy. Here, we also discussed for patents related to the topic. PMID:27009124

  5. Recent Advances in Protein and Peptide Drug Delivery: A Special Emphasis on Polymeric Nanoparticles

    PubMed Central

    Patel, Ashaben; Patel, Mitesh; Yang, Xiaoyan; Mitra, Ashim K.

    2015-01-01

    Proteins and peptides are widely indicated in many diseased states. Parenteral route is the most commonly employed method of administration for therapeutic proteins and peptides. However, requirement of frequent injections due to short in vivo half-life results in poor patient compliance. Non-invasive drug delivery routes such as nasal, transdermal, pulmonary, and oral offer several advantages over parenteral administration. Intrinsic physicochemical properties and low permeability across biological membrane limit protein delivery via non-invasive routes. One of the strategies to improve protein and peptide absorption is by delivering through nanostructured delivery carriers. Among nanocarriers, polymeric nanoparticles (NPs) have demonstrated significant advantages over other delivery systems. This article summarizes the application of polymeric NPs for protein and peptide drug delivery following oral, nasal, pulmonary, parenteral, transdermal, and ocular administrations. PMID:25106908

  6. [Uncommon mycobacterial infections in domestic and zoo animals: four cases with special emphasis on pathology].

    PubMed

    Steiger, K; Ellenberger, C; Schüppel, K F; Richter, E; Schmerbach, K; Krautwald-Junghanns, M E; Wünnemann, K; Eulenberger, K; Schoon, H A

    2003-09-01

    Infections caused by classical tubercle bacilli are rare during the last years. Nevertheless, diseases caused by other mycobacteria have to be considered clinically and in diagnostic pathology especially in cases of immunosuppression and due to their potential zoonosis risk. An infection by mycobacteria was diagnosed in four animals (Mayotte Maki, Blue-headed Parrot, Patagonian sealion, Beagle) necropsied between 1995 and 2002 in the Institute of Veterinary-Pathology of the University of Leipzig. The Maki, the blue-headed parrot and the dog showed a disseminated character of the disease caused by Mycobacterium genavense (monkey and bird) resp. Mycobacterium avium (dog), while an open chronical tuberculosis of the lungs due to a pathogenic member of Mycobacterium tuberculosis complex was observed in the seal. All these bacteria are potential causes of zoonoses. So, if granulomatous or disseminated histiocytic alterations are detected in diagnostic pathology, mycobacterial infections should always be included in differential diagnoses and require careful aetiological investigations by histopathological and bacteriological methods. PMID:14560447

  7. Integrative Therapies in Anxiety Treatment with Special Emphasis on the Gut Microbiome

    PubMed Central

    Schnorr, Stephanie L.; Bachner, Harriet A.

    2016-01-01

    Over the past decade, research has shown that diet and gut health affects symptoms expressed in stress related disorders, depression, and anxiety through changes in the gut microbiota. Psycho-behavioral function and somatic health interaction have often been ignored in health care with resulting deficits in treatment quality and outcomes. While mental health care requires the professional training in counseling, psychotherapy and psychiatry, complimentary therapeutic strategies, such as attention to a nutritional and diverse diet and supplementation of probiotic foods, may be integrated alongside psychotherapy treatment models. Development of these alternative strategies is predicated on experimental evidence and diligent research on the biology of stress, fear, anxiety-related behaviors, and the gut-brain connection. This article provides a brief overview on biological markers of anxiety and the expanding nutritional literature relating to brain health and mental disorders. A case study demonstrates an example of a biopsychosocial approach integrating cognitive psychotherapy, dietary changes, and mindfulness activities, in treating symptoms of anxiety. This case study shows a possible treatment protocol to explore the efficacy of targeting the gut-brain-axis that may be used as an impetus for future controlled studies. PMID:27698624

  8. 77 FR 28393 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-14

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and..., Cholera and HIV/AIDS Response, FOA GH12-001, and Research and Technical Assistance for Public Health Laboratories in Haiti to Support Post Earthquake Reconstruction, Cholera and HIV/AIDS Response, FOA...

  9. 78 FR 66937 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... Building Assistance for High Impact HIV Prevention, Funding Opportunity Announcement (FOA) PS14-1403...), the Centers for Disease Control and Prevention (CDC) announces the aforementioned SEP: Times and...

  10. 77 FR 291 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-04

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... Research on Use of Mobile Applications (``app'') to Increase HIV Testing Behavior and HIV Prevention with... Section 10(a)(2) of the Federal Advisory Committee Act (Pub. L. 92-463), the Centers for Disease...

  11. 76 FR 32213 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP); Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-03

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and... Immunodeficiency Virus (HIV) Prevention Projects for Young Men of Color, Funding Opportunity Announcement (FOA... More Information: Harriette Lynch, Public Health Analyst, Extramural Programs, National Center for...

  12. Fisher's contributions to genetics and heredity, with special emphasis on the Gregor Mendel controversy.

    PubMed

    Piegorsch, W W

    1990-12-01

    R. A. Fisher is widely respected for his contributions to both statistics and genetics. For instance, his 1930 text on The Genetical Theory of Natural Selection remains a watershed contribution in that area. Fisher's subsequent research led him to study the work of (Johann) Gregor Mendel, the 19th century monk who first developed the basic principles of heredity with experiments on garden peas. In examining Mendel's original 1865 article, Fisher noted that the conformity between Mendel's reported and proposed (theoretical) ratios of segregating individuals was unusually good, "too good" perhaps. The resulting controversy as to whether Mendel "cooked" his data for presentation has continued to the current day. This review highlights Fisher's most salient points as regards Mendel's "too good" fit, within the context of Fisher's extensive contributions to the development of genetical and evolutionary theory.

  13. Boiling heat transfer of nanofluids--special emphasis on critical heat flux.

    PubMed

    Kim, Sung Joong; Kim, Hyungdae

    2013-11-01

    As innovative nanotechnology-based heat-transfer media, nanofluids have evoked considerable interest among researchers owing to their improved thermal properties as well as their extendable applications to various high-power thermal systems. This paper presents a comprehensive review of recent research developments and patents pertaining to nanofluid boiling heat transfer. Nanofluids definitely offer a wide range of potential improvements in boiling heat-transfer performance. However, experimental data available from different studies are currently beset by numerous contradictions, suggesting that the fundamental mechanisms of nanofluid boiling heat transfer are not yet well understood. Consequently application of these technologies has been limited in some aspects. Only a small number of patents related to nanofluid boiling heat transfer have thus far been reported in the literature. Based on the present review, future technological development and research requirements in this area are outlined in line with technical challenges. To utilize nanofluid boiling heat-transfer technologies for practical applications, more systematic and fundamental studies are required to understand the physical mechanisms involved.

  14. Integrative Therapies in Anxiety Treatment with Special Emphasis on the Gut Microbiome

    PubMed Central

    Schnorr, Stephanie L.; Bachner, Harriet A.

    2016-01-01

    Over the past decade, research has shown that diet and gut health affects symptoms expressed in stress related disorders, depression, and anxiety through changes in the gut microbiota. Psycho-behavioral function and somatic health interaction have often been ignored in health care with resulting deficits in treatment quality and outcomes. While mental health care requires the professional training in counseling, psychotherapy and psychiatry, complimentary therapeutic strategies, such as attention to a nutritional and diverse diet and supplementation of probiotic foods, may be integrated alongside psychotherapy treatment models. Development of these alternative strategies is predicated on experimental evidence and diligent research on the biology of stress, fear, anxiety-related behaviors, and the gut-brain connection. This article provides a brief overview on biological markers of anxiety and the expanding nutritional literature relating to brain health and mental disorders. A case study demonstrates an example of a biopsychosocial approach integrating cognitive psychotherapy, dietary changes, and mindfulness activities, in treating symptoms of anxiety. This case study shows a possible treatment protocol to explore the efficacy of targeting the gut-brain-axis that may be used as an impetus for future controlled studies.

  15. 76 FR 39879 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-07

    ... Immunodeficiency Virus (HIV) Prevention Projects for Young Men of Color Who Have Sex with Men and Young Transgender... evaluation of applications received in response to ``HIV Prevention Projects for Young Men of Color Who Have...: Harriette Lynch, Public Health Analyst, Extramural Programs, National Center for HIV, Hepatitis and...

  16. 76 FR 45575 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-29

    ... Immunodeficiency Virus (HIV) Prevention Projects for Young Men of Color Who Have Sex with Men and Young Transgender..., Extramural Programs, National Center for HIV, Hepatitis and Sexually Transmitted Diseases Prevention,...

  17. 76 FR 59133 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-23

    ... Immunodeficiency Virus (HIV) Prevention Projects for Young Men of Color Who Have Sex with Men and Young Transgender... include the initial review, discussion, and evaluation of an application received in response to ``HIV..., National Center for HIV, Hepatitis and Sexually Transmitted Diseases Prevention, CDC, 1600 Clifton Road,...

  18. Verifying Elimination Programs with a Special Emphasis on Cysticercosis Endpoints and Postelimination Surveillance

    PubMed Central

    Handali, Sukwan; Pawitan, Yudi

    2012-01-01

    Methods are needed for determining program endpoints or postprogram surveillance for any elimination program. Cysticercosis has the necessary effective strategies and diagnostic tools for establishing an elimination program; however, tools to verify program endpoints have not been determined. Using a statistical approach, the present study proposed that taeniasis and porcine cysticercosis antibody assays could be used to determine with a high statistical confidence whether an area is free of disease. Confidence would be improved by using secondary tests such as the taeniasis coproantigen assay and necropsy of the sentinel pigs. PMID:23213490

  19. Baking loss of bread with special emphasis on increasing water holding capacity.

    PubMed

    Kotoki, D; Deka, S C

    2010-01-01

    Potato flour (PF), hydroxypropyl methylcellulose (HPMC) and honey were used as baking agents and their effects on baking loss and sensory quality were studied. PF at 1, 2 and 4% levels decreased baking loss followed by HPMC and honey. Water absorption was substantially high with the HPMC (70.8-80.8%) and PF (61.7-71.7%) compared to honey and normal standard bread. PF incorporation increased shelf-life (6-7 days) as compared to HPMC and honey. HPMC incorporated bread had higher moisture content (36.8-38.0%) followed by PF (34.5-35.8%) and honey (34.7%). The ash content was in the order of PF (1%) > honey (4%) > PF (2%) > normal bread > HPMC (0.5 g) > PF (4%) > HPMC (1 g) > HPMC (1.5 g). PF incorporated bread had sensorily highest acceptance followed by HPMC and honey.

  20. Early Childhood Intervention Partnerships on the Navajo Reservation with an Emphasis on Special Education.

    ERIC Educational Resources Information Center

    Sealander, Karen; Medina, Catherine; Gamble, Armanda; Pettigrew, Bobbie; Snyder, Maria; White, Sherri; Begay, Mary Helen; Bradley, Brian; Bradley-Wilkinson, Evangeline; Heimbecker, Connie; McCarty, Nellie; Nelson, Bernita; Nelson, Jacob; Smith, Jody; Whitehair, Marsha; Redsteer, Denise; Prater, Greg

    Kayenta Unified School District (KUSD) is located in the Navajo Reservation in Arizona. In addition to serving over 2,600 K-12 students, KUSD collaborates with the Navajo Nation and the Kayenta community to provide three early childhood education programs: Acceptance Belonging Caring (ABC) preschool, Navajo Nation Head Start, and Child Care…

  1. Yeasts in malting, with special emphasis on Wickerhamomyces anomalus (synonym Pichia anomala).

    PubMed

    Laitila, Arja; Sarlin, Tuija; Raulio, Mari; Wilhelmson, Annika; Kotaviita, Erja; Huttunen, Timo; Juvonen, Riikka

    2011-01-01

    Malted barley is a major raw material of beer, as well as distilled spirits and several food products. The production of malt (malting) exploits the biochemical reactions of a natural process, grain germination. In addition to germinating grain, the malting process includes another metabolically active component: a diverse microbial community that includes various types of bacteria and fungi. Therefore, malting can be considered as a complex ecosystem involving two metabolically active groups. Yeasts and yeast-like fungi are an important part of this ecosystem, but previously the significance of yeasts in malting has been largely underestimated. Characterization and identification of yeasts in industrial processes revealed 25 ascomycetous yeasts belonging to 10 genera, and 18 basidiomycetous yeasts belonging to 7 genera. In addition, two ascomycetous yeast-like fungi belonging to the genera Aureobasidium and Exophiala were commonly detected. Yeasts and yeast-like fungi produced extracellular hydrolytic enzymes with a potentially positive contribution to the malt enzyme spectrum. Several ascomycetous yeast strains showed strong antagonistic activity against field and storage moulds, Wickerhamomyces anomalus (synonym Pichia anomala) being the most effective species. Malting studies revealed that W. anomalus VTT C-04565 effectively restricted Fusarium growth and hydrophobin production during malting and prevented beer gushing. In order to broaden the antimicrobial spectrum and to improve malt brewhouse performance, W. anomalus could be combined with other starter cultures such as Lactobacillus plantarum. Well-characterized microbial mixtures consisting of barley and malt-derived microbes open up several possibilities to improve malt properties and to ensure the safety of the malting process.

  2. Trichosanthes dioica Roxb.: Pharmacognostic standardization of the female leaves with special emphasis on the microscopic technique

    PubMed Central

    Singh, Saurabh; Chauhan, M. G.; Machawal, Lalit

    2011-01-01

    Objectives: Standardization is essentially a measure for ensuring the quality control of herbal drugs. But the gender of the plant affecting the quality of crude drugs does not appear to have been taken care of so far. Today, sophisticated modern research tools for the evaluation of the plant drugs are available but the microscopic method is one of the simplest and cheapest methods. Methods and Materials: The pharmacognostic investigation of the fresh, powdered, and anatomical sections of the female leaves of Trichosanthes dioica Roxb. was carried out to determine its bioprospective constants. Results and Discussion: Externally, the leaves possess a cordate base, a sinuate and dentate margin, an acute to acuminate apex, and both surfaces are very rough with rigid hair surface. Internally, it shows the presence of anomocytic stomata, unicellular, and both glandular and simple covering trichomes scattered as such throughout or attached with the cells of the epidermis. Majority of the glandular trichomes are with a four-to-five-celled uniseriate stalk and unicellular head; very few are short and with uni- to bicellular stalk and uni- to multicellular head especially from that of the petiole region. Simple covering, multicellular, uniseriate thick-walled trichomes are of various sizes. Usually cells of both simple and glandular trichomes are often embedded with cystolith. Phytochemical studies of the powdered leaves revealed the presence of alkaloids, resins, glycosides, flavonoids and some carbohydrates. The pharmacognostic profile of the leaves will assist in the standardization for quality, purity, and sample identification. PMID:21687354

  3. Evolutionary space platform concept study. Volume 2, part A: SASP special emphasis trade studies

    NASA Technical Reports Server (NTRS)

    1982-01-01

    Efforts are in progress to define an approach to provide a simple and cost effective solution to the problem of long duration space flight. This approach involves a Space Platform in low Earth orbit, which can be tended by the Space Shuttle and which will provide, for extended periods of time, stability, utilities and access for a variety of replaceable payloads. The feasibility of an evolutionary space system which would cost effectively support unmanned payloads in groups, using a Space Platform which provides centralized basic subsystems is addressed.

  4. The posterior interosseous artery flap: clinical results with special emphasis on donor site morbidity.

    PubMed

    Neuwirth, Maximilian; Hubmer, Martin; Koch, Horst

    2013-05-01

    This study evaluated the clinical results, and especially the donor site morbidity of the posterior interosseous artery flap. A retrospective study included 40 patients with defects covered with posterior interosseous flaps. Twenty-one patients were available for a follow-up examination to assess donor site morbidity by evaluating the dimensions and quality of the donor site scar and the forearm contour as well as complaints and subjective satisfaction with the aesthetic result. The flaps and related donor sites healed uneventfully in 29 cases (72.5%); healing was delayed in 11 cases (27.5%), with total flap loss in two cases. Further surgery was required in six cases. The quality of the donor site scar rated with the Vancouver Scar Scale averaged 2.4 points. Eleven patients (55%) reported impaired sensibility around the donor site and four patients (20%) had physical complaints. Subjective and objective donor site evaluation revealed significantly lower donor site morbidity for directly closed as opposed to skin grafted donor sites, although subjectively, there was a high level of satisfaction in both groups. Our data indicated that the posterior interosseous flap is a valuable option for the management of soft-tissue defects on the dorsum of the hand, due to its anatomical reliability and soft and pliable tissue, its low donor site morbidity and high patient acceptance.

  5. Epidemiology of elephantiasis with special emphasis on podoconiosis in Ethiopia: A literature review.

    PubMed

    Yimer, Mulat; Hailu, Tadesse; Mulu, Wondemagegn; Abera, Bayeh

    2015-06-01

    Elephantiasis is a symptom of a variety of diseases that is characterized by the thickening of the skin and underlying tissues, especially in the legs, male genitals and female breasts. Some conditions having this symptom include: Elephantiasis nostras, due to longstanding chronic lymphangitis; Elephantiasis tropica or lymphatic filariasis, caused by a number of parasitic worms, particularly Wuchereria bancrofti; non-filarial elephantiasis or podoconiosis, an immune disease caused by heavy metals affecting the lymph vessels; proteus syndrome, the genetic disorder of the so-called Elephant Man, etc. Podoconiosis is a type of lower limb tropical elephantiasis distinct from lymphatic filariasis. Lymphatic filariasis affects all population at risk, whereas podoconiosis predominantly affects barefoot subsistence farmers in areas with red volcanic soil. Ethiopia is one of the countries with the highest number of podoconiosis patients since many people are at risk to red-clay soil exposure in many parts of the country. The aim of this review was to know the current status and impact of podoconiosis and its relevance to elephantiasis in Ethiopia. To know the epidemiology and disease burden, the literatures published by different scholars were systematically reviewed. The distribution of the disease and knowledge about filarial elephantiasis and podoconiosis are not well known in Ethiopia. It is relatively well studied in southern Ethiopia but data from other parts of the country are limited. Moreover, programmes that focus on diagnosis, treatment, prevention and control of filarial elephantiasis and podoconiosis are also non-existent even in endemic areas. Furthermore, the disease mapping has not been carried out country-wide. Therefore, in order to address these gaps, Ethiopian Ministry of Health needs to take initiative for undertaking concrete research and mapping of the disease in collaboration with stakeholders. PMID:26119541

  6. [Physiology and pathology of reproduction in domesticated New World camelids with special emphasis on ultrasonography].

    PubMed

    Hoops, M; Kauffold, J

    2013-01-01

    The number of New World camelids in Germany is increasing. Owners and breeders are usually well educated regarding their animals. For practitioners, this means being up-to-date with respect to their veterinary knowledge. This includes the physiology and pathology of reproduction. Specifics of reproduction in domesticated New World camelids are an induced ovulation, the absence of cyclic sexual activity, a relatively long gestation of 336-349 days and a predominantly left-horn gestation. Ultrasonography plays an important role as part of the gynecological examination. Generally, the ultrasonographic examination can be performed transrectally and transcutaneously in the left or right flanks. Transrectal ultrasonography has to be carried out with particular caution to avoid rectal injuries. An accurate pregnancy diagnosis by transrectal scanning is possible starting from day 20 of pregnancy; using transcutaneous scanning, diagnosis is accurate starting on days 50-60 (left flank) or from day 90 (right flank) of pregnancy, respectively. Ultrasonography is also appropriate to examine the non-gravid uterus and the ovaries. Based on 5 years of experience working with farmed New World camelids, the article describes the physiology and pathology of reproduction in domesticated New World camelids. Particular consideration is given to the ultrasonographical examination of the genital organs.

  7. 75 FR 22815 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-30

    ... Opportunity Announcement (FOA) DP 10-001, Initial Review In accordance with Section 10(a)(2) of the Federal... Craniofacial Malformation, FOA DP 10-001.'' Contact Person for More Information: Michael Dalmat,...

  8. 77 FR 2548 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Grants for...

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    2012-01-18

    ...), Funding Opportunity Announcement (FOA) CE12-001, Initial Review In accordance with Section 10(a)(2) of the... to ``Grants for Injury Control Research Centers, Panel 2, FOA CE12-001''. Contact Person for...

  9. 76 FR 9578 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Conducting...

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    2011-02-18

    ... Laboratory Training Programs (FETPs/FELTPs), Funding Opportunity Announcement (FOA) GH11-001, Initial Review... Epidemiology and Laboratory Training Programs (FETPs/FELTPs), FOA GH11-001, initial review.'' Contact...

  10. 75 FR 22816 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Revitalizing Core...

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    2010-04-30

    ... Health Specialists Network (EHS-Net) Research (U01), Funding Opportunity Announcement (FOA) EH10-001... Environmental Health Programs through the EHS-Net Research (U01), FOA EH10-001.'' Agenda items are subject...

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    2011-02-18

    ... (U01), Funding Opportunity Announcement (FOA) DD11-001, Initial Review In accordance with Section 10(a... Registry--Clinic Demonstration Project (U01), FOA DD11-001, initial review.'' Contact Person for...

  12. 75 FR 7283 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-18

    ... Influenza and Other Zoonotic Diseases, Funding Opportunity Announcement (FOA) CK10-001, Initial Review In... other Zoonotic Diseases, FOA CK10-001.'' Contact Person for More Information: Gregory Anderson, M.S.,...

  13. 76 FR 27327 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Meeting

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    2011-05-11

    ... Zoonotic Diseases in Vietnam, Funding Opportunity Announcement (FOA) IP11-005, The Incidence and Etiology of Influenza-Associated Community- Acquired Pneumonia in Hospitalized Persons Study; FOA IP11-011...; FOA IP11-012, Influenza Vaccine Efficacy in Tropical and Developing Countries; FOA IP11-013,...

  14. 75 FR 13559 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Long Term...

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    2010-03-22

    ... Cytomegalovirus (CMV) Infection, Funding Opportunity Announcement (FOA) IP10-006, Initial Review In accordance... in response to ``Long Term Outcomes of Infants Identified with Congenital CMV Infection, FOA...

  15. 76 FR 13413 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP); Meeting

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    2011-03-11

    ... Zoonotic Diseases in Vietnam, Funding Opportunity Announcement (FOA) IP11-005; The Incidence and Etiology of Influenza-Associated Community- Acquired Pneumonia in Hospitalized Persons Study, FOA IP11-011..., FOA IP11-012; Influenza Vaccine Efficacy in Tropical and Developing Countries, FOA IP11-013;...

  16. 77 FR 2549 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Grants for...

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    2012-01-18

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  17. 75 FR 21339 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Developing...

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    2010-04-23

    ... Antimicrobial Resistant Pathogens, Funding Opportunity Announcement (FOA) CI10-002; Initial Review In accordance..., FOA CI10-002.'' Contact Person for More Information: Gregory Anderson, M.S., M.P.H., Scientific...

  18. 78 FR 732 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

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    2013-01-04

    ... Announcement (FOA) CK13-001, initial review. In accordance with Section 10(a)(2) of the Federal Advisory... Control of Vector- Borne and Zoonotic Infectious Diseases in Uganda, FOA CK13-001.'' Contact Person...

  19. 75 FR 39033 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Patient...

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    2010-07-07

    ... (FOA) CI10-003, Initial Review In accordance with Section 10(a)(2) of the Federal Advisory Committee...), Enhancing Epidemiology and Laboratory Capacity, Funding Opportunity Announcement FOA CI10- 003.''...

  20. 75 FR 28810 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Conducting...

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    2010-05-24

    ... Opportunity Announcement (FOA) GH10-003, Initial Review In accordance with Section 10(a)(2) of the Federal... Kenya (Panel C),'' FOA GH10-003. Contact Person for More Information: Christine Morrison,...

  1. 76 FR 9018 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Emerging...

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    2011-02-16

    ... Opportunity Announcement (FOA), CK11-002, Initial Review In accordance with Section 10(a)(2) of the Federal... Sentinel Network (EISN) Research, FOA CK11- 002, initial review.'' Contact Person for More...

  2. 75 FR 30844 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Conducting...

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    2010-06-02

    ... Opportunity Announcement (FOA) GH10-003, Initial Review In accordance with Section 10(a)(2) of the Federal... Kenya (Panel B),'' FOA GH10-003. Contact Person for More Information: Sheree Marshall Williams,...

  3. 77 FR 28393 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

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    2012-05-14

    ... Prevent Prescription Drug Overdoses, FOA CE12-007, initial review. In accordance with Section 10(a)(2) of... to ``Research to Prevent Prescription Drug Overdoses, FOA CE12-007, initial review.'' Contact...

  4. 75 FR 9606 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Public...

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    2010-03-03

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  6. 77 FR 21778 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

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    2012-04-11

    ... among High Risk Female Teens, FOA DP12- 001, initial review. In accordance with Section 10(a)(2) of the... among High Risk Female Teens, FOA DP12-001, initial review.'' Contact Person For More Information:...

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    2010-05-24

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  8. 77 FR 12844 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Reducing...

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    2012-03-02

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  9. 75 FR 28622 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Conducting...

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    2010-05-21

    ... Opportunity Announcement (FOA) GH10-003, Initial Review In accordance with Section 10(a)(2) of the Federal... Kenya (U01)(Panel A),'' FOA GH10-003. Contact Person for More Information: Susan Stanton,...

  10. 75 FR 76987 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-10

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  11. 76 FR 13414 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Evaluation...

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    2011-03-11

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  12. 76 FR 18555 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

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    2011-04-04

    ... Evaluation of the Modes of Influenza Virus Transmission among Humans, Funding Opportunity Announcement (FOA... Influenza Virus Transmission among Humans, FOA IP11-001.'' Contact Person for More Information:...

  13. 75 FR 78999 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Centers for...

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    2010-12-17

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  14. 77 FR 2549 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Grants for...

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    2012-01-18

    ... Opportunity Announcement (FOA) CE12-001, Initial Review In accordance with Section 10(a)(2) of the Federal... Control Research Centers, Panel 3, FOA CE12-001.'' Contact Person for More Information: Donald...

  15. 75 FR 7284 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-18

    ... (FOA) CK10-002, Initial Review In accordance with Section 10(a)(2) of the Federal Advisory Committee... Malaria, FOA CK10-002.'' Contact Person for More Information: Gregory Anderson, M.S., M.P.H.,...

  16. 78 FR 17412 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Funding...

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    2013-03-21

    ... Region of the United States (U01), FOA EH13-001, initial review. SUMMARY: This document corrects a notice that was published in the Federal Register on February 28, 2013 (78 FR 13677). The meeting announcement... Environment of Low- Income Renovated Multifamily Housing in the Western Region of the United States (U01),...

  17. 78 FR 9055 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial review

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    2013-02-07

    ..., Funding Opportunity Announcement (FOA) IP13- 002; and Strengthening Global Animal-Human Interface Activities for Avian Influenza and other Zoonotic Diseases, FOA CK13-002, initial review. In accordance with... Infections in Panama and Central America Region, FOA IP13-002; and Strengthening Global...

  18. 75 FR 55806 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Patient...

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    2010-09-14

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  19. 76 FR 13621 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel; Teleconference

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    2011-03-14

    ... Disorders and Longitudinal Assessment of Outcomes, Funding Opportunity Announcement (FOA) DD11-004, and Pilot Longitudinal Data Collection to Inform Public Health--Fragile X Syndrome, FOA DD11-007, initial... Assessment of Outcomes, FOA DD11-004, and Pilot Longitudinal Data Collection to Inform Public...

  20. 77 FR 12844 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Development...

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    2012-03-02

    ... Intervention for Changing Behaviors Related to Cytomegalovirus Transmission in Pregnant Women, FOA DD12-005... Women, FOA DD12-005, initial review.'' For Further Information Contact: M. Chris Langub,...