Sample records for aging special emphasis

  1. 78 FR 63207 - Special Emphasis Panel; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Healthcare Research and Quality Special Emphasis Panel; Meeting AGENCY: Agency for Healthcare Research and Quality, HHS. ACTION: Notice. SUMMARY...), announcement is made of an Agency for Healthcare Research and Quality (AHRQ) Special Emphasis Panel (SEP...

  2. Visual Representation in Mathematics: Special Education Teachers' Knowledge and Emphasis for Instruction

    ERIC Educational Resources Information Center

    van Garderen, Delinda; Scheuermann, Amy; Poch, Apryl; Murray, Mary M.

    2018-01-01

    The use of visual representations (VRs) in mathematics is a strongly recommended practice in special education. Although recommended, little is known about special educators' knowledge of and instructional emphasis about VRs. Therefore, in this study, the authors examined special educators' own knowledge of and their instructional emphasis with…

  3. A Special Education Systems Simulation Model: Teacher Training Emphasis.

    ERIC Educational Resources Information Center

    Jones, Wayne; And Others

    The authors illustrate the application of a systems approach for educational decision-makers through utilization of a special education systems simulation model with emphasis on teacher training. It is noted that the model provides a procedure to answer "what if" type questions before actually implementing a proposed program. Discussed are the…

  4. 78 FR 43003 - Biomedical Laboratory Research and Development Service, Special Emphasis Panel-Amyotrophic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-18

    ... Emphasis Panel--Amyotrophic Lateral Sclerosis (ALS) Brain Bank, Notice of Meeting The Department of... Special Emphasis Panel--ALS Brain Bank will meet on July 23, 2013, from 9 a.m. until 4 p.m. in Building 57... VA ALS Brain Bank for its continued funding. The VA ALS Brain Bank is a project of high programmatic...

  5. 76 FR 49771 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-11

    ..., Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Special Interest Project (SIP), Systematic Review of Effective Community-based... Discussed: The meeting will include the initial review, discussion, and evaluation of ``Systematic Review of...

  6. 76 FR 51985 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-19

    ..., Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Special Interest Project (SIP): Systematic Review of Effective Community-based Interventions of Clinical Preventive Services for Older Adults, SIP11-045, initial review. Correction: This...

  7. 75 FR 4406 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Occupational...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Occupational Safety and Health Training Projects Grants, Request for Applications (RFA) 06-484; and Occupational Safety and Health Educational...

  8. 75 FR 76987 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-10

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Epidemiologic and Ecologic... evaluation of applications received in response to ``Epidemiologic and Ecologic Determinants of Monkeypox in...

  9. 75 FR 43993 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Patient Protection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-27

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Patient Protection and Affordable Care Act (PPACA), Emerging Infections Program (EIP), Enhancing Epidemiology and Laboratory Capacity...

  10. 75 FR 52356 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: National Human...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-25

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: National Human Immunodeficiency Virus (HIV) Behavioral Surveillance, Funding Opportunity Announcement PS11-001; Initial Review Correction...

  11. 75 FR 13769 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Natural...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Natural Experiments and... meeting will include the initial review, discussion, and evaluation of ``Natural Experiments and...

  12. 75 FR 28810 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Addressing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-24

    ... evaluation of applications received in response to ``Addressing Emerging Infectious Diseases and Related... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Addressing Emerging Infectious...

  13. 77 FR 12844 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Reducing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Reducing Health Disparities Among... to ``Reducing Health Disparities among People with Intellectual Disabilities, FOA DD12-003, initial...

  14. 75 FR 77645 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pregnancy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-13

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pregnancy Risk Assessment... initial review, discussion, and evaluation of ``Pregnancy Risk Assessment Monitoring System (PRAMS), DP11...

  15. 76 FR 27327 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Virologic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Virologic Evaluation of the Modes of Influenza Virus Transmission Among Humans, Funding Opportunity Announcement, IP11-001 Correction...

  16. 76 FR 10908 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Maternal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-28

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Maternal Vitamin D Status and....D., Scientific Review Officer, CDC, National Center for Chronic Disease Prevention and Health...

  17. 76 FR 3908 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): The Association of Genetic... meeting will include the initial review, discussion, and evaluation of ``The Association of Genetic...

  18. 75 FR 78998 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Addressing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Addressing Global TB Prevention and Control in all Populations and Strengthening Health Facilities, Laboratories, Prisons and Other...

  19. 75 FR 6675 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Human...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-10

    ..., Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Human Immunodeficiency Virus (HIV... evaluation of applications received in response to ``HIV Prevention Projects for Community Based..., Extramural Programs, National Center for HIV, Hepatitis and Sexually Transmitted Diseases Prevention, 1600...

  20. 76 FR 19995 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Funding...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-11

    ..., Extramural Research Program Office, National Center for Chronic Disease Prevention and Health Promotion, CDC... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Funding Opportunity Announcement...

  1. 75 FR 9606 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-03

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Public Health Research on... in response to ``Public Health Research on Craniofacial Malformation, FOA DP 10-001.'' Contact Person...

  2. 77 FR 3269 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Data...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention (CDC) Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Data Coordinating Center for Autism and Other Developmental Disabilities Research and Epidemiologic Studies, RFA DD12-001, Initial...

  3. 76 FR 4703 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pregnancy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-26

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pregnancy Risk Assessment Monitoring System (PRAMS), DP11-001 Panel D, Initial Review Notice of Cancellation: This notice was published...

  4. 76 FR 5379 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pregnancy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pregnancy Risk Assessment..., discussion, and evaluation of ``Pregnancy Risk Assessment Monitoring System (PRAMS), DP11-001 Panels A, B...

  5. 75 FR 7281 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Translating...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Translating Research Into Action... of the Director, Extramural Research Program Office, 4770 Buford Highway, NE., Mailstop K-92, Atlanta...

  6. 76 FR 12122 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-04

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): The Association of Genetic Biomarkers and Hereditary Hemochromatosis, DD11-008, Initial Review Correction: This notice was published in...

  7. 76 FR 13414 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pilot...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pilot Longitudinal Data Collection To Inform Public Health--Fragile X Syndrome, DD11-007, Initial Review Notice of Cancellation: This...

  8. 75 FR 30844 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Conducting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Conducting Public Health Research... in response to ``Conducting Public Health Research in Kenya (Panel B),'' FOA GH10-003. Contact Person...

  9. 75 FR 28810 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Conducting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-24

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Conducting Public Health Research... in response to ``Conducting Public Health Research in Kenya (Panel C),'' FOA GH10-003. Contact Person...

  10. 76 FR 13621 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Family...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Family History and Diamond Blackfan Anemia, DD11- 010, Initial Review Correction: This notice was published in the Federal Register on...

  11. 76 FR 9785 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Human...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Human Immunodeficiency Virus (HIV) Prevention Projects for Young Men of Color Who Have Sex With Men and Young Transgender Persons of Color...

  12. 75 FR 28261 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Improved...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-20

    ... in response to ``Improved Diagnostics Lyme Borreliosis,'' FOA CK10-005. FOR MORE INFORMATION CONTACT..., Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Improved Diagnostics for Lyme Borreliosis, Funding Opportunity Announcement (FOA) CK10-005; Initial Review In accordance with Section 10(a...

  13. 75 FR 29561 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Surveillance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-26

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Surveillance, Natural History, Quality of Care and Outcomes of Diabetes Mellitus with Onset in Childhood and Adolescence, RFA DP 10-001...

  14. 75 FR 26266 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Developing Novel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Developing Novel Diagnostic Tests To Improve Surveillance for Antimicrobial Resistant Pathogens, Funding Opportunity Announcement CI10-002; Initial Review Correction: This notice was...

  15. 76 FR 20355 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Funding...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-12

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Funding Opportunity Announcement (FOA), Initial Review The meeting announced below concerns ``Conducting Public Health Research in Thailand by the Ministry of Public Health (MOPH)...

  16. 75 FR 78999 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Maternal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ..., Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Maternal Vitamin D Status and..., discussion, and evaluation of ``Maternal Vitamin D Status and Preterm Birth, DP11-002, initial review.'' Contact Person for More Information: Donald Blackman, PhD, Scientific Review Officer, CDC, National Center...

  17. Geostationary platform systems concepts definition follow-on study. Volume 2A: Technical Task 2 LSST special emphasis

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The results of the Large Space Systems Technology special emphasis task are presented. The task was an analysis of structural requirements deriving from the initial Phase A Operational Geostationary Platform study.

  18. 77 FR 25180 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-27

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Evaluation of Dengue Epidemiology, Outcomes, and Prevention in Sentinel...

  19. 78 FR 15015 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panels (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-08

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panels (SEP): Initial Review The meeting announced below concerns Epidemiology, Prevention and Treatment of Influenza and other Respiratory...

  20. 78 FR 28221 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Youth Violence Training and Technical Assistance, Funding Opportunity Announcement...

  1. Bedrock aquifers in the northern San Rafael Swell area, Utah, with special emphasis on the Navajo Sandstone

    USGS Publications Warehouse

    Hood, J.W.; Patterson, D.J.

    1984-01-01

    This report presents the results of a study of bedrock aquifers in the northern San Rafael Swell area, Utah (fig. 1), with special emphasis on the Navajo Sandstone of Triassic(?) and Jurassic age. The study was made by the U.S. Geological Survey in cooperation with the Utah Department of Natural Resources, Division of Water Rights. Fieldwork was done mainly during March 1979-July 1980, with supplemental testing and observations during August-December 1980.The principal objectives of this study were to determine: (1) Well yields of the bedrock formations, (2) the capability of formations to yield, over the long term, water chemically suitable for presently (1980) known uses, and (3) effects of withdrawals from wells on the surface-water supply in the Colorado River Basin.

  2. 75 FR 78999 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Centers for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Centers for Autism and... evaluation of ``Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE), FOA...

  3. 75 FR 5601 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-03

    ... Committee: National Institute on Aging Special Emphasis Panel, Alzheimer's Disease Genetics. Date: March 4... of Committee: National Institute on Aging Special Emphasis Panel, Drug Development for Alzheimer's...

  4. 76 FR 9018 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Emerging...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-16

    ..., Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Emerging Infections Sentinel... with Section 10(a)(2) of the Federal Advisory Committee Act (Pub. L. 92-463), the Centers for Disease Control and Prevention (CDC), announces the aforementioned meeting: Times and Dates: 12 p.m.-2 p.m., March...

  5. 77 FR 291 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-04

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns National HIV Behavioral Surveillance For Young Men Who Have Sex With Men, Funding...

  6. 75 FR 9423 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Impact of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Impact of Japanese Encephalitis... to ``Impact of Japanese Encephalitis Vaccination in Cambodia, FOA CK10-003.'' Contact Person for More...

  7. 75 FR 69686 - Disease, Disability, and Injury Prevention and Control; Special Emphasis Panel: Epi-Centers for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-15

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control; Special Emphasis Panel: Epi-Centers for the Prevention of... following: Place: 12 Executive Park Drive, Atlanta, Georgia 30333. Contact Person for More Information...

  8. 77 FR 16232 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): A Pilot...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-20

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): A Pilot Surveillance for High... in response to ``A Pilot Surveillance for High Impact/Low Prevalence Congenital and Inherited...

  9. 76 FR 367 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Minority HIV...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-04

    ..., Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Minority HIV/AIDS Research... Researchers To Conduct HIV/AIDS Epidemiologic and Prevention Research, Funding Opportunity Announcement (FOA... HIV/AIDS Research Initiative (MARI) to Build Capacity in Black and Hispanic Communities and Among...

  10. 75 FR 22411 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ....gov . Name of Committee: National Institute on Aging Special Emphasis Panel; Healthy Aging Pathways... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Lead Drug...

  11. 75 FR 29350 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Miner Safety...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-25

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Miner Safety and Health Training--Western United States, Request for Application (RFA) OH10-001, Initial Review In accordance with section...

  12. 78 FR 37232 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ....nih.gov . Name of Committee: National Institute on Aging Special Emphasis Panel; Treatment of Obesity... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; NIA DBSR DATASETS...

  13. 77 FR 2549 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Grants for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Grants for Injury Control Research Centers (Panel 3), Funding Opportunity Announcement (FOA) CE12-001, Initial Review In accordance with Section 10(a)(2) of the Federal Advisory...

  14. Lhermitte's sign: Review with special emphasis in oncology practice.

    PubMed

    Gemici, Cengiz

    2010-05-01

    Lhermitte's sign (LS) is characterized by electric shock like sensation, spreading along the spine in a cervico-caudal direction and also into both arms and legs, which is felt upon forward flexion of the neck. It is a myelopathy resulting from damage to sensory axons at the dorsal columns of the cervical or thoracic spinal cord and a well-known clinical sign in neurology practice. Patients with cancer may present with LS due to various causes either related to the tumor itself or to its treatment. Spinal cord tumors, radiotherapy and chemotherapy are possible causes of LS observed in oncology practice. While LS is observed with a frequency of 3.6-13% in large patient groups receiving radiotherapy for head and neck and thoracic malignancies, the true incidence of chemotherapy and spinal cord tumor induced LS is unknown with only few reported cases in the literature. In the present article, various pathologies causing Lhermitte's sign are reviewed with special emphasis on the implications of this sign in oncology practice. 2009 Elsevier Ireland Ltd. All rights reserved.

  15. Pharmaceutical solvates, hydrates and amorphous forms: A special emphasis on cocrystals.

    PubMed

    Healy, Anne Marie; Worku, Zelalem Ayenew; Kumar, Dinesh; Madi, Atif M

    2017-08-01

    Active pharmaceutical ingredients (APIs) may exist in various solid forms, which can lead to differences in the intermolecular interactions, affecting the internal energy and enthalpy, and the degree of disorder, affecting the entropy. Differences in solid forms often lead to differences in thermodynamic parameters and physicochemical properties for example solubility, dissolution rate, stability and mechanical properties of APIs and excipients. Hence, solid forms of APIs play a vital role in drug discovery and development in the context of optimization of bioavailability, filing intellectual property rights and developing suitable manufacturing methods. In this review, the fundamental characteristics and trends observed for pharmaceutical hydrates, solvates and amorphous forms are presented, with special emphasis, due to their relative abundance, on pharmaceutical hydrates with single and two-component (i.e. cocrystal) host molecules. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Organogels in Drug Delivery: A Special Emphasis on Pluronic Lecithin Organogels.

    PubMed

    Alsaab, Hashem; Bonam, Sindhu Prabha; Bahl, Dherya; Chowdhury, Pallabita; Alexander, Kenneth; Boddu, Sai Hs

    2016-01-01

    Organogels have emerged as an alternative carrier for small and macromolecules via transdermal, oral, rectal and ophthalmic routes. Pluronic lecithin organogels (PLO gels) are lecithin-based organogels widely used in compounding pharmacies as a vehicle for enhancing the transdermal permeability of many therapeutic drugs. However, the scientific and systematic evidence in support of how well PLO gels help in transdermal delivery is scanty. Recently, some clinical studies have reported nearly complete lack of bioavailability of certain topically administered drugs from PLO gels. The present review aims at summarizing gels and organogels, with a focus on the use of PLO gels in transdermal drug delivery. A special emphasis is placed on controversies looming over the use of PLO gels as a delivery platform for drugs via transdermal route. This article is open to POST-PUBLICATION REVIEW. Registered readers (see "For Readers") may comment by clicking on ABSTRACT on the issue's contents page.

  17. 75 FR 16489 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-01

    ... Emphasis Panel; Adiposity, Aging, and Stem Cells. Date: June 23, 2010. Time: 1 p.m. to 5 p.m. Agenda: To... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Effect of Energy...

  18. 78 FR 21960 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... and Alzheimer's Disease. Date: June 12, 2013. Time: 11 a.m. to 2 p.m. Agenda: To review and evaluate... Special Emphasis Panel; Alzheimer's Disease Prevention. Date: July 11, 2013. Time: 1 p.m. to 4 p.m. Agenda... of Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's Disease Prevention...

  19. 42 CFR 408.45 - Deduction from age 72 special payments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Deduction from age 72 special payments. 408.45... § 408.45 Deduction from age 72 special payments. (a) Deduction of premiums. SMI premiums are deducted from age 72 special payments made under section 228 of the Act or the payments are withheld under...

  20. 42 CFR 408.45 - Deduction from age 72 special payments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 2 2013-10-01 2013-10-01 false Deduction from age 72 special payments. 408.45... § 408.45 Deduction from age 72 special payments. (a) Deduction of premiums. SMI premiums are deducted from age 72 special payments made under section 228 of the Act or the payments are withheld under...

  1. "Special Educational Needs" of the Elderly: A Trap for the Unwary? Research Study.

    ERIC Educational Resources Information Center

    Ageing International, 1989

    1989-01-01

    A British study of mainstreamed and special needs classes for older adults found that the special education approach encourages a narrow perspective of aging and an emphasis on disability. At Simon Fraser University, a certificate program for senior citizens determined that seniors like age-integrated classes and instructors need training in…

  2. Morphological dynamics of mitochondria--a special emphasis on cardiac muscle cells.

    PubMed

    Hom, Jennifer; Sheu, Shey-Shing

    2009-06-01

    Mitochondria play a critical role in cellular energy metabolism, Ca(2+) homeostasis, reactive oxygen species generation, apoptosis, aging, and development. Many recent publications have shown that a continuous balance of fusion and fission of these organelles is important in maintaining their proper function. Therefore, there is a steep correlation between the form and function of mitochondria. Many major proteins involved in mitochondrial fusion and fission have been identified in different cell types, including heart. However, the functional role of mitochondrial dynamics in the heart remains, for the most part, unexplored. In this review we will cover the recent field of mitochondrial dynamics and its physiological and pathological implications, with a particular emphasis on the experimental and theoretical basis of mitochondrial dynamics in the heart.

  3. 76 FR 65203 - National Institute on Aging

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-20

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... unwarranted invasion of personal privacy. Name of Committee: National Institute on Aging Special Emphasis... and evaluate grant applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin...

  4. 76 FR 21386 - National Institute on Aging

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-15

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Organelle Lifespan.... Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  5. Specialized science.

    PubMed

    Casadevall, Arturo; Fang, Ferric C

    2014-04-01

    As the body of scientific knowledge in a discipline increases, there is pressure for specialization. Fields spawn subfields that then become entities in themselves that promote further specialization. The process by which scientists join specialized groups has remarkable similarities to the guild system of the middle ages. The advantages of specialization of science include efficiency, the establishment of normative standards, and the potential for greater rigor in experimental research. However, specialization also carries risks of monopoly, monotony, and isolation. The current tendency to judge scientific work by the impact factor of the journal in which it is published may have roots in overspecialization, as scientists are less able to critically evaluate work outside their field than before. Scientists in particular define themselves through group identity and adopt practices that conform to the expectations and dynamics of such groups. As part of our continuing analysis of issues confronting contemporary science, we analyze the emergence and consequences of specialization in science, with a particular emphasis on microbiology, a field highly vulnerable to balkanization along microbial phylogenetic boundaries, and suggest that specialization carries significant costs. We propose measures to mitigate the detrimental effects of scientific specialism.

  6. Specialized Science

    PubMed Central

    Fang, Ferric C.

    2014-01-01

    As the body of scientific knowledge in a discipline increases, there is pressure for specialization. Fields spawn subfields that then become entities in themselves that promote further specialization. The process by which scientists join specialized groups has remarkable similarities to the guild system of the middle ages. The advantages of specialization of science include efficiency, the establishment of normative standards, and the potential for greater rigor in experimental research. However, specialization also carries risks of monopoly, monotony, and isolation. The current tendency to judge scientific work by the impact factor of the journal in which it is published may have roots in overspecialization, as scientists are less able to critically evaluate work outside their field than before. Scientists in particular define themselves through group identity and adopt practices that conform to the expectations and dynamics of such groups. As part of our continuing analysis of issues confronting contemporary science, we analyze the emergence and consequences of specialization in science, with a particular emphasis on microbiology, a field highly vulnerable to balkanization along microbial phylogenetic boundaries, and suggest that specialization carries significant costs. We propose measures to mitigate the detrimental effects of scientific specialism. PMID:24421049

  7. 76 FR 30374 - National Institute on Aging; Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... unwarranted invasion of personal privacy. Name of Committee: National Institute on Aging Special Emphasis... 90401. Contact Person: Ramesh Vemuri, PhD, Chief, Scientific Review Branch, National Institute on Aging...

  8. Morphological Dynamics of Mitochondria – A Special Emphasis on Cardiac Muscle Cells

    PubMed Central

    Hom, Jennifer; Sheu, Shey-Shing

    2010-01-01

    Mitochondria play a critical role in cellular energy metabolism, Ca2+ homeostasis, reactive oxygen species generation, apoptosis, aging, and development. Many recent publications have shown that a continuous balance of fusion and fission of these organelles is important in maintaining their proper function. Therefore, there is a steep correlation between the form and function of mitochondria. Many major proteins involved in mitochondrial fusion and fission have been identified in different cell types, including heart. However, the functional role of mitochondrial dynamics in the heart remains, for the most part, unexplored. In this review we will cover the recent field of mitochondrial dynamics and its physiological and pathological implications, with a particular emphasis on the experimental and theoretical basis of mitochondrial dynamics in the heart. PMID:19281816

  9. [Pathogenic factors of vibrios with special emphasis on Vibrio vulnificus].

    PubMed

    Shinoda, Sumio

    2005-07-01

    Bacteria of the genus Vibrio are normal habitants of the aquatic environment and play roles for biocontrole of aquatic ecosystem, but some species are believed to be human pathogens. These species can be classified into two groups according to the types of diseases they cause: the gastrointestinal infections and the extraintestinal infections. The pathogenic species produce various pathogenic factors including enterotoxin, hemolysin, cytotoxin, protease, siderophore, adhesive factor, and hemagglutinin. We studied various pathogenic factors of vibrios with special emphasis on protease and hemolysin of V. vulnificus. V. vulnificus is now recognized as being among the most rapidly fatal of human pathogens, although the infection is appeared in patients having underlying disease(s) such as liver dysfunction, alcoholic cirrhosis or haemochromatosis. V. vulnificus protease (VVP) is thought to be a major toxic factor causing skin damage in the patients having septicemia. VVP is a metalloprotease and degrades a number of biologically important proteins including elastin, fibrinogen, and plasma proteinase inhibitors of complement components. VVP causes skin damages through activation of the Factor XII-plasma kallikrein-kinin cascade and/or exocytotic histamine release from mast cells, and a haemorrhagic lesion through digestion of the vascular basement membrane. Thus, the protease is the most probable candidate for tissue damage and bacterial invasion during an infection. Pathogenic roles and functional mechanism of other factors including hemolysins of V. vulnificus and V. mimicus are also shown in this review article.

  10. Sports‐related acute and chronic avulsion injuries in children and adolescents with special emphasis on tennis

    PubMed Central

    Vandervliet, Everhard J M; Vanhoenacker, Filip M; Snoeckx, Annemie; Gielen, Jan L; Van Dyck, Pieter; Parizel, Paul M

    2007-01-01

    Acute and chronic sports‐related muscle and tendon injuries are not infrequent in youngsters. In particular, the physis is prone to trauma as it constitutes the weakest part of the immature skeleton. The type of sports activity determines the location of the lesion. Most commonly, apophyses of the hip and pelvis are subject to avulsion. The purpose of this paper is to give a short overview of the pathogenesis, location, prevalence and imaging characteristics of acute and chronic avulsion injuries in the immature skeleton, with special emphasis on tennis‐related injuries. Tennis‐related injuries particularly involve apophyses of the ischial tuberosity, the anterior inferior or superior iliac spine and the iliac crest. PMID:17586583

  11. 75 FR 54159 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-03

    ...: National Institute on Aging Special Emphasis Panel, Stem Cells and Genomic Integrity Through Senescense.... 93.866, Aging Research, National Institutes of Health, HHS) Dated: August 26, 2010. Jennifer S...

  12. 75 FR 4829 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-29

    ... Institute on Aging Special Emphasis Panel; Summer Research Training In Aging For Medical Students--NIA T35... review and evaluate contract proposals. Place: National Institute on Aging, Gateway Building, 7201..., Aging Research, National Institutes of Health, HHS) [[Page 4830

  13. Aging reduces neural specialization in ventral visual cortex

    PubMed Central

    Park, Denise C.; Polk, Thad A.; Park, Rob; Minear, Meredith; Savage, Anna; Smith, Mason R.

    2004-01-01

    The present study investigated whether neural structures become less functionally differentiated and specialized with age. We studied ventral visual cortex, an area of the brain that responds selectively to visual categories (faces, places, and words) in young adults, and that shows little atrophy with age. Functional MRI was used to estimate neural activity in this cortical area, while young and old adults viewed faces, houses, pseudowords, and chairs. The results demonstrated significantly less neural specialization for these stimulus categories in older adults across a range of analyses. PMID:15322270

  14. 77 FR 11563 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-27

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Systems Biology of... Officer, Scientific Review Branch, National Institute on Aging, Gateway Bldg., 2C212, 7201 Wisconsin...

  15. 75 FR 43995 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-27

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, Healthy Aging... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... grant applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite...

  16. Abortion trends from 1996 to 2011 in Estonia: special emphasis on repeat abortion

    PubMed Central

    2014-01-01

    Background The study aimed to describe the overall and age-specific trends of induced abortions from 1996 to 2011 with an emphasis on socio-demographic characteristics and contraceptive use of women having had repeat abortions in Estonia. Methods Data were retrieved from the Estonian Medical Birth and Abortion Registry and Statistics Estonia. Total induced abortion numbers, rates, ratios and age-specific rates are presented for 1996–2011. The percentage change in the number of repeat abortions within selected socio-demographic subgroups, contraception use and distribution of induced abortions among Estonians and non-Estonians for the first, second, third, fourth and subsequent abortions were calculated for the periods 1996–2003 and 2004–2011. Results Observed trends over the 16-year study period indicated a considerable decline in induced abortions with a reduction in abortion rate of 57.1%, which was mainly attributed to younger cohorts. The percentage of women undergoing repeat abortions fell steadily from 63.8% during 1996–2003 to 58.0% during 2004–2011. The percentage of women undergoing repeat abortions significantly decreased over the 16 years within all selected socio-demographic subgroups except among women with low educational attainment and students. Within each time period, a greater percentage of non-Estonians than Estonians underwent repeat abortions and obtained third and subsequent abortions. Most women did not use any contraceptive method prior to their first or subsequent abortion. Conclusion A high percentage of women obtaining repeat abortions reflects a high historical abortion rate. If current trends continue, a rapid decline in repeat abortions may be predicted. To decrease the burden of sexual ill health, routine contraceptive counselling, as standard care in the abortion process, should be seriously addressed with an emphasis on those groups - non-Estonians, women with lower educational attainment, students and women with children

  17. 77 FR 34394 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Healthy Aging and... grant applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite...

  18. 75 FR 9908 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-04

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, Health, Behavior... and evaluate grant applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin...

  19. 77 FR 65005 - National Institute on Aging Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-24

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Juvenile... grant applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite...

  20. 75 FR 25273 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, Basis of... grant applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite...

  1. 75 FR 26268 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, ARRA--Behavioral... evaluate grant applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue...

  2. 77 FR 40370 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, Aging and.... Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  3. 76 FR 32977 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-07

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, Aging and.... Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  4. 77 FR 63843 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Aging and Sleep.... Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  5. 78 FR 30932 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Mobility and Aging.... Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  6. 75 FR 79386 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Hormone Therapy and Cognitive Aging. Date: January 11, 2011. Time: 11 a.m. to 12 p.m. Agenda: To review and evaluate...

  7. 20 CFR 404.383 - Special age 72 payment amounts.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Special age 72 payment amounts. 404.383 Section 404.383 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance Benefits; Period of...

  8. 20 CFR 404.383 - Special age 72 payment amounts.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Special age 72 payment amounts. 404.383 Section 404.383 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance Benefits; Period of...

  9. 20 CFR 404.383 - Special age 72 payment amounts.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Special age 72 payment amounts. 404.383 Section 404.383 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance Benefits; Period of...

  10. 20 CFR 404.383 - Special age 72 payment amounts.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Special age 72 payment amounts. 404.383 Section 404.383 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance Benefits; Period of...

  11. 20 CFR 404.383 - Special age 72 payment amounts.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Special age 72 payment amounts. 404.383 Section 404.383 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents' and Survivors' Insurance Benefits; Period of...

  12. 76 FR 17929 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-31

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... unwarranted invasion of personal privacy. Name of Committee: National Institute on Aging Special Emphasis...: To review and evaluate grant applications. Place: National Institute on Aging, Gateway Building, 7201...

  13. 76 FR 23827 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-28

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel Osteoarthritis...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892...

  14. 78 FR 57167 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Disability and... applications. Place: National Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue...

  15. 78 FR 51196 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-20

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Juvenile... grant applications. Place: National Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin...

  16. 78 FR 4423 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Worm Intervention... applications. Place: National Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue...

  17. 77 FR 1941 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-12

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; GEMSSTAR. Date...: Rebecca J. Ferrell, Ph.D., Scientific Review Officer, National Institute on Aging, Gateway Building, Rm...

  18. 75 FR 11188 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Beeson Meeting...: William Cruce, PhD, Scientific Review Officer, National Institute on Aging, Scientific Review Branch...

  19. 76 FR 35901 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, Signal.... Place: National Institute of Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  20. 77 FR 34396 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Changing Long Term... grant applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite...

  1. 77 FR 2737 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Development and....m. Agenda: To review and evaluate contract proposals. Place: National Institute on Aging, Gateway...

  2. 76 FR 57064 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, AD Genetics... Person: William Cruce, PhD, Scientific Review Officer, National Institute on Aging, Scientific Review...

  3. 76 FR 42719 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-19

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, The NIA Health and... agreement applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite...

  4. 76 FR 5391 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Pepper Centers.... Markowska, PhD, DSC, Scientific Review Branch, National Institute on Aging, 7201 Wisconsin Avenue, Suite...

  5. 77 FR 5030 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel Testosterone.... Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  6. 78 FR 36200 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Longitudinal Study... proposals. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212...

  7. 76 FR 60058 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-28

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... unwarranted invasion of personal privacy. Name of Committee: National Institute on Aging Special Emphasis...: Ramesh Vemuri, PhD, Chief, Scientific Review Branch, National Institute On Aging, National Institutes of...

  8. 77 FR 40368 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel Age, Gene..., Genes and Longevity in Humans. Date: July 27, 2012. Time: 12:30 p.m. to 4 p.m. Agenda: To review and...

  9. 77 FR 74677 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-17

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Cell Dependent and... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... and evaluate grant applications. Place: National Institute on Aging, Gateway Building, Suite 2C212...

  10. 75 FR 11188 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, Nursing Home.... Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  11. 76 FR 6628 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Sex Differences in.... Johnson, PhD, Scientific Review Officer, National Institutes on Aging, National Institutes of Health, 7201...

  12. 77 FR 21790 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Loan Repayment.... Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD...

  13. 77 FR 53207 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-31

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, Pepper Centers....D., DSC, Scientific Review Branch, National Institute on Aging, 7201 Wisconsin Avenue, Suite 2c212...

  14. 75 FR 35821 - National Institute On Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute On Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel Member Conflict SEP...). Contact Person: Ramesh Vemuri, PhD, Chief, Scientific Review Branch, National Institute on Aging, National...

  15. 78 FR 16273 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel. Date: April 1... Institute on Aging, National Institutes of Health, Gateway Building, 7201 Wisconsin Avenue, Suite 2C-212...

  16. 75 FR 18511 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-12

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, Loan Repayment...: National Institute on Aging. Gateway Building. 7201 Wisconsin Avenue, Suite 2C212. Bethesda, MD 20892...

  17. 78 FR 32408 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-30

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel Senile Dementia.... Place: National Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda, MD...

  18. 75 FR 3476 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Clinical Services...: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892...

  19. 78 FR 9403 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-08

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; CALERIE Dataset.... Place: National Institute on Aging, Gateway Building, Room 2C212, 7201 Wisconsin Avenue, Bethesda, MD...

  20. Special Operations Forces Language and Culture Needs Assessment Project: Training Emphasis: Language and Culture

    DTIC Science & Technology

    2010-02-25

    gave significantly higher emphasis ratings (i.e., a statistically significant difference between SOF operators and SOF leaders). Responses were made...i.e., a statistically significant difference between SOF operators and SOF leaders). Responses were made on the following scale: 1 = No emphasis, 2...missions?” Means with an asterisk (*) indicate that the group gave significantly higher emphasis ratings (i.e., a statistically significant difference

  1. 78 FR 35041 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel SWAN. Date: June 27... Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda, MD 20892, (Telephone...

  2. An In-Depth Review of the Current Practica, Associated with Early Childhood through Twelfth Grade Special Education Programs, for the Benefit of Higher Education Programs, with an Emphasis in Obtaining a M.Ed. in Special Education

    ERIC Educational Resources Information Center

    Cady, Jennifer

    2010-01-01

    In order to guide organizational growth in the Master's in Education with an emphasis in Special Education program, offered at Southwestern College, an in-depth qualitative study was conducted with participants from three specific realms located in the state of Kansas. Participants from the Kansas State Department of Education, Southwestern…

  3. 75 FR 67381 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel HIV, HAART and AGING. Date: November 23, 2010. Time: 1 p.m. to 5 p.m. Agenda: To review and evaluate grant applications...

  4. 75 FR 39698 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-12

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, Network Infrastructure for Aging Research. Date: July 20, 2010. Time: 12 p.m. to 4 p.m. Agenda: To review and evaluate...

  5. 75 FR 63497 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Genetic Determinants of Healthy Aging. Date: November 10, 2010. Time: 1 p.m. to 5 p.m. Agenda: To review and evaluate...

  6. 78 FR 69432 - National Institute on Aging; Cancellation of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-19

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Cancellation of Meeting Notice is hereby given of the cancellation of the National Institute on Aging Special Emphasis Panel, December 18, 2013, 2:00 p.m. to December 18, 2013, 3:15 p.m., National Institute of Aging...

  7. Space Construction System Analysis. Special Emphasis Studies

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Generic concepts were analyzed to determine: (1) the maximum size of a deployable solar array which might be packaged into a single orbit payload bay; (2) the optimal overall shape of a large erectable structure for large satellite projects; (3) the optimization of electronic communication with emphasis on the number of antennas and their diameters; and (4) the number of beams, traffic growth, and projections and frequencies were found feasible to package a deployable solar array which could generate over 250 kilowatts of electrical power. Also, it was found that the linear-shaped erectable structure is better for ease of construction and installation of systems, and compares favorably on several other counts. The study of electronic communication technology indicated that proliferation of individual satellites will crowd the spectrum by the early 1990's, so that there will be a strong tendency toward a small number of communications platforms over the continental U.S.A. with many antennas and multiple spot beams.

  8. 78 FR 66368 - National Institute on Aging; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... Aging Special Emphasis Panel, October 17, 2013, 12:00 p.m. to October 17, 2013, 05:00 p.m., National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, which was...

  9. 78 FR 66373 - National Institute on Aging; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... Aging Special Emphasis Panel, October 16, 2013, 02:00 p.m. to October 16, 2013, 05:00 p.m., National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, which was...

  10. 78 FR 20669 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Management of the Primate Aging Database Date: April 23, 2013. Time: 1:00 p.m. to 4:00 p.m. Agenda: To review and evaluate...

  11. 78 FR 66369 - National Institute on Aging; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... Aging Special Emphasis Panel, October 17, 2013, 12:00 p.m. to October 17, 2013, 04:00 p.m., National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, which was...

  12. 78 FR 9708 - National Institute on Aging Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-11

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Comparative Physiology of Aging. Date: March 14, 2013. Time: 12:30 p.m. to 3:30 p.m. Agenda: To review and evaluate grant... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging...

  13. 76 FR 55691 - National Institute on Aging Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-08

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Aminergic Function and Brain Aging II. Date: October 21, 2011. Time: 12:30 p.m. to 4:30 p.m. Agenda: To review and... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging...

  14. 77 FR 56855 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... Special Emphasis Panel; Oxidative Stress and Aging. Date: November 8, 2012. Time: 11:00 a.m. to 3:00 p.m.... 93.866, Aging Research, National Institutes of Health, HHS)*COM019* Dated: September 10, 2012...

  15. 76 FR 54238 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-31

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, Work Levels..., Bethesda, MD 20892 (Telephone Conference Call). Contact Person: Rebecca J. Ferrell, PhD, Scientific Review... Person: Rebecca J. Ferrell, PhD, Scientific Review Officer, National Institute on Aging, Gateway Building...

  16. 75 FR 8374 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-24

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, New Invertebrate Models for the Biology of Aging. Date: March 18, 2010. Time: 8:30 a.m. to 3:30 p.m. Agenda: To review and...

  17. 75 FR 56116 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, Alzheimer's Disease Genetics. Date: October 4, 2010. Time: 8 p.m. to 9 p.m. Agenda: To review and evaluate grant...

  18. 75 FR 39549 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-09

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; ARRA--MIND MRI...

  19. 78 FR 26054 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-03

    ... Validation of Novel Targets for Alzheimer's Disease. Date: June 25, 2013. Time: 11:30 a.m. to 5:30 p.m... Committee: National Institute on Aging Special Emphasis Panel; Drug Development for Alzheimer's Disease...

  20. 78 FR 63999 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's Disease Sequencing Project. Date: October 29, 2013. Time: 8:00 a.m. to 6:00 p.m. Agenda: To review and...

  1. Determination of lactic acid with special emphasis on biosensing methods: A review.

    PubMed

    Pundir, Chandra S; Narwal, Vinay; Batra, Bhawna

    2016-12-15

    Lactic acid (2-Hydroxypropanoic acid) is generated from pyruvic acid under anaerobic condition in skeletal muscles, brain, red blood cells, and kidney. Lactate in normal human subjects get cleared very quickly at a rate of 320mmol/L/hr, mostly by liver metabolism and re-conversion of lactate back to pyruvate. Measurement of lactate level in serum is required for the differential diagnosis and medical management of hyperlactatemia, cardiac arrest and resuscitation, sepsis, reduced renal excretion, hypoxia induced cancer, decreased extra hepatic metabolism, intestinal infarction and lactic acidosis. Determination of lactate is also important in dairy products and beverages to access their quality. Among the various methods available for detection of lactate, most are complicated, nonspecific, less sensitive and require time-consuming sample pretreatment, expensive instrumental set-up and trained persons to operate, specifically for chromatographic methods. Biosensing methods overcome these drawbacks, as these are simple, fast, specific and highly sensitive. Lactate biosensors reported so far, work optimally within 3-180s, between pH, 5.5-8.5 and temperature 22°C to 37°C and lactate concentration ranging from 10 to 2000µM. These biosensors have been employed to measure lactate level in embryonic cell culture, beverages, urine, and serum samples and reused upto 200-times within a period of 7-216 days. This review presents the principles, merits and demerits of various analytical methods for lactate determination with special emphasis on lactate biosensors. The future perspective for improvement of analytic performance of lactate biosensors are discussed. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. 77 FR 29677 - National Institute on Aging Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    ..., [email protected] . Name of Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's Disease Study. Date: July 3, 2012. Time: 12:00 p.m. to 5:00 p.m. Agenda: To review and evaluate grant...

  3. 78 FR 26793 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-08

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Asthma in Older Adults. Date: May 29, 2013. Time: 12:00 p.m. to 3:00 p.m. Agenda: To review and evaluate grant...

  4. 75 FR 32489 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-08

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; ARRA--Behavioral Economics C.E.R.--Pilot Research. Date: June 25, 2010. Time: 1 p.m.to 5 p.m. Agenda: To review and evaluate...

  5. 75 FR 32954 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-10

    ... Aging Special Emphasis Panel; Antecedent Markers for Alzheimer's Disease. Date: July 26, 2010. Time: 2 p..., Disease, and Death. Date: June 23-24, 2010. Time: 3 p.m. to 12 p.m. Agenda: To review and evaluate grant...

  6. Isolation of compound and CNS depressant activities of Mikania scandens Willd with special emphasis to brain biogenic amines in mice.

    PubMed

    Pal, Dilipkumar; Mazumder, Upal Kanti

    2014-12-01

    Mikania scandens, a twining herb that grows as a weed in India and Bangladesh is used as vegetables and is a good source of vitamin A, C, B complex, mikanin, sesquiterpenes, betasitosterin, stigmasterol and friedelin. The present communication reports CNS depressant activities with special emphasis to brain biogenic amines in mice. Ethanol extract of leaves of M. scandens (EEMS) was prepared by Soxhalation and analyzed chemically. EEMS potentiated sleeping time induced by pentobarbitone, diazepam and meprobamate and showed significant reduction in the number of writhes and stretches. EEMS caused significant protection against pentylene tetrazole-induced convulsion and increased catecholamines and brain amino acids level significantly. Results showed that EEMS produced good CNS depressant effects in mice.

  7. Comparative assessment of metallurgical recovery of metals from electronic waste with special emphasis on bioleaching.

    PubMed

    Priya, Anshu; Hait, Subrata

    2017-03-01

    Waste electrical and electronic equipment (WEEE) or electronic waste (e-waste) is one of the fastest growing waste streams in the urban environment worldwide. The core component of printed circuit board (PCB) in e-waste contains a complex array of metals in rich quantity, some of which are toxic to the environment and all of which are valuable resources. Therefore, the recycling of e-waste is an important aspect not only from the point of waste treatment but also from the recovery of metals for economic growth. Conventional approaches for recovery of metals from e-waste, viz. pyrometallurgical and hydrometallurgical techniques, are rapid and efficient, but cause secondary pollution and economically unviable. Limitations of the conventional techniques have led to a shift towards biometallurgical technique involving microbiological leaching of metals from e-waste in eco-friendly manner. However, optimization of certain biotic and abiotic factors such as microbial species, pH, temperature, nutrients, and aeration rate affect the bioleaching process and can lead to profitable recovery of metals from e-waste. The present review provides a comprehensive assessment on the metallurgical techniques for recovery of metals from e-waste with special emphasis on bioleaching process and the associated factors.

  8. Chloride Homeostasis in Neurons With Special Emphasis on the Olivocerebellar System: Differential Roles for Transporters and Channels.

    PubMed

    Rahmati, Negah; Hoebeek, Freek E; Peter, Saša; De Zeeuw, Chris I

    2018-01-01

    The intraneuronal ionic composition is an important determinant of brain functioning. There is growing evidence that aberrant homeostasis of the intracellular concentration of Cl - ([Cl - ] i ) evokes, in addition to that of Na + and Ca 2+ , robust impairments of neuronal excitability and neurotransmission and thereby neurological conditions. More specifically, understanding the mechanisms underlying regulation of [Cl - ] i is crucial for deciphering the variability in GABAergic and glycinergic signaling of neurons, in both health and disease. The homeostatic level of [Cl - ] i is determined by various regulatory mechanisms, including those mediated by plasma membrane Cl - channels and transporters. This review focuses on the latest advances in identification, regulation and characterization of Cl - channels and transporters that modulate neuronal excitability and cell volume. By putting special emphasis on neurons of the olivocerebellar system, we establish that Cl - channels and transporters play an indispensable role in determining their [Cl - ] i and thereby their function in sensorimotor coordination.

  9. Limited access to special education services for school-aged children with developmental delay.

    PubMed

    Twardzik, Erica; Smit, Ellen; Hatfield, Bridget; Odden, Michelle C; Dixon-Ibarra, Alicia; MacDonald, Megan

    2018-01-01

    Current policy in Oregon limits eligibility of children diagnosed with developmental delay for school-based services. Due to eligibility definitions, children with developmental delay may face additional barriers transitioning from early intervention/early childhood special education into school-based special education services. Examine the relationship between enrollment in school-based special education programs given a change in primary disability diagnosis. Logistic regression models were fit for children who enrolled in early intervention/early childhood special education services with a primary disability diagnosis of developmental delay and changed primary disability diagnosis before third grade (n=5076). Odds of enrollment in future special education were greater in children with a change in primary disability diagnosis after the age of five in comparison to children that had a change in primary disability diagnosis before the age of five, while adjusting for demographic characteristics (adjusted odds ratio: 2.37, 95% CI 1.92, 2.92). Results suggest that children who are diagnosed with a developmental delay and exit early childhood special education due to maximum age of eligibility are more likely to enroll in special education compared to children without a gap in service access. Gaps in service access during early development are associated with the need for supportive services later on in life. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. 75 FR 54890 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-09

    ... Institute on Aging Special Emphasis Panel; Aminergic Function in Brain Aging and Alzheimer's Disease. Date... U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C...

  11. Project-oriented teaching model about specialized courses in the information age

    NASA Astrophysics Data System (ADS)

    Chen, Xiaodong; Wang, Jinjiang; Tian, Qingguo; Wang, Yi; Cai, Huaiyu

    2017-08-01

    Specialized courses play a significant role in the usage of basic knowledge in the practical application for engineering college students. The engineering data available has sharply increased since the beginning of the information age in the 20th century, providing much more approaches to study and practice. Therefore, how to guide students to make full use of resources for active engineering practice learning has become one of the key problems for specialized courses. This paper took the digital image processing course for opto-electronic information science and technology major as an example, discussed the teaching model of specialized course in the information age, put forward the "engineering resource oriented model", and fostered the ability of engineering students to use the basic knowledge to innovate and deal with specific project objectives. The fusion of engineering examples into practical training and teaching encourages students to practice independent engineering thinking.

  12. Current drug therapy of patients with BPH-LUTS with the special emphasis on PDE5 inhibitors

    PubMed Central

    Govorov, Alexander; Kasyan, George; Priymak, Diana; Pushkar, Dmitry

    2016-01-01

    Introduction Benign prostatic hyperplasia (BPH) is the most common cause of lower urinary tract symptom (LUTS) development in men [1]. The intensity of the symptoms may vary from mild to severe, significantly affecting the quality of life. Erectile dysfunction (ED) is one of the most challenging issues in modern urology that significantly influences the quality of life in men worldwide. The objective of this literature review was to analyze the current drug therapies of patients with BPH-LUTS, with the special emphasis on PDE5 inhibitors. Material and methods The authors searched the literature for the period from 2000 until 2015 in MEDLINE and PubMed. Results Twenty-three articles were selected based on their reliability. A detailed analysis of the selected papers was performed. Primary attention was given to articles describing the use of PDE5. Works describing the use of different groups of drugs in patients with BPH-LUTS were also selected. Conclusions The current literature analysis suggests that the introduction of PDE5 inhibitors in clinical practice for the treatment of patients with BPH-LUTS will allow for significant expansion of the therapeutic options for the treatment of this disease. PMID:28127458

  13. Current drug therapy of patients with BPH-LUTS with the special emphasis on PDE5 inhibitors.

    PubMed

    Kolontarev, Konstantin; Govorov, Alexander; Kasyan, George; Priymak, Diana; Pushkar, Dmitry

    2016-01-01

    Benign prostatic hyperplasia (BPH) is the most common cause of lower urinary tract symptom (LUTS) development in men [1]. The intensity of the symptoms may vary from mild to severe, significantly affecting the quality of life. Erectile dysfunction (ED) is one of the most challenging issues in modern urology that significantly influences the quality of life in men worldwide. The objective of this literature review was to analyze the current drug therapies of patients with BPH-LUTS, with the special emphasis on PDE5 inhibitors. The authors searched the literature for the period from 2000 until 2015 in MEDLINE and PubMed. Twenty-three articles were selected based on their reliability. A detailed analysis of the selected papers was performed. Primary attention was given to articles describing the use of PDE5. Works describing the use of different groups of drugs in patients with BPH-LUTS were also selected. The current literature analysis suggests that the introduction of PDE5 inhibitors in clinical practice for the treatment of patients with BPH-LUTS will allow for significant expansion of the therapeutic options for the treatment of this disease.

  14. [White House Conference on Aging, 1981. Creating an Age Integrated Society: Implications for the Media. Report and Executive Summary of the Technical Committee.

    ERIC Educational Resources Information Center

    Tanenbaum, Marc H.; And Others

    The relationship of older Americans to the new media culture of society is the focus of this Technical Committee Report. The work of two committee-appointed subcommittees on stereotypes and new media technology are explained with a special emphasis on the influence of television. Age stereotyping is examined in prime time television, daytime…

  15. Graduates' Perspectives on a National Specialized Program in Social Work and Aging

    ERIC Educational Resources Information Center

    Greenfield, Emily A.; Shpiegel, Svetlana

    2012-01-01

    Recognizing the growing need for social workers with specialized training in aging, the Hartford Partnership Program for Aging Education (HPPAE) has developed as a nationwide initiative to enhance aging education for master's-level social work students. This study presents a content analysis of answers to 2 open-ended questions in a national…

  16. 38 CFR 6.14 - Cash value; other than special endowment at age 96 plan policy.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... special endowment at age 96 plan policy. 6.14 Section 6.14 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS UNITED STATES GOVERNMENT LIFE INSURANCE Cash Value § 6.14 Cash value; other than special endowment at age 96 plan policy. Provisions for cash value shall become effective at the...

  17. 78 FR 75358 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-11

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Vitamin D Trials...; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U... 20892 (Telephone Conference Call). Contact Person: Rebecca J. Ferrell, Ph.D., Scientific Review Officer...

  18. Neurodiversity: The Future of Special Education?

    ERIC Educational Resources Information Center

    Armstrong, Thomas

    2017-01-01

    The way special education is carried out in U.S. schools must change. Special education has become weighed down by its emphasis on deficits and disorders: As regular education has opened to new ways of thinking about brain neuroplasticity, growth mindsets, and other innovations, special education has held fast to its diagnostic categories,…

  19. The Shift in Emphasis From Risk-Based to Age-Based Hepatitis C Virus (HCV) Testing in the US Tends to Remove Injection Drug Use From Discourse on HCV.

    PubMed

    Jordan, Ashly E; Perlman, David C

    2017-02-23

    Hepatitis C virus (HCV) infection is hyperendemic among people who inject drugs; nonsterile drug injection is the principle risk for HCV acquisition. Due to gaps in the HCV care continuum, there have been recommendations in the United States emphasizing age-rather than risk-based testing strategies. The central research focus of this project is to explore the meanings and implications of the shift in emphasis from risk-based to age-based HCV testing with regard to people who use drugs. Content analysis and critical discourse analysis, informed by eco-social theory, were used to examine relevant documents. Fifteen documents were assessed for eligibility; 6 documents comprised the final set reviewed. In content analysis, age-based testing was both mentioned more frequently and was supported more strongly than risk-based testing. Risk-based testing was frequently mentioned in terms minimizing its use and drug use was often mentioned only euphemistically. The reframed emphasis largely removed discussion of injection drug use from discussion of HCV risks. Shifting the emphasis of HCV testing from testing based on specific routes of transmission and risk to testing based on age removes injection drug use from HCV discourse. This has the potential to either facilitate HCV care for drug users or to further stigmatize and marginalize drug use and people who use drugs. The potential implications of this shift in testing emphasis for public health merit further investigation.

  20. Gradient waveform pre-emphasis based on the gradient system transfer function.

    PubMed

    Stich, Manuel; Wech, Tobias; Slawig, Anne; Ringler, Ralf; Dewdney, Andrew; Greiser, Andreas; Ruyters, Gudrun; Bley, Thorsten A; Köstler, Herbert

    2018-02-25

    The gradient system transfer function (GSTF) has been used to describe the distorted k-space trajectory for image reconstruction. The purpose of this work was to use the GSTF to determine the pre-emphasis for an undistorted gradient output and intended k-space trajectory. The GSTF of the MR system was determined using only standard MR hardware without special equipment such as field probes or a field camera. The GSTF was used for trajectory prediction in image reconstruction and for a gradient waveform pre-emphasis. As test sequences, a gradient-echo sequence with phase-encoding gradient modulation and a gradient-echo sequence with a spiral read-out trajectory were implemented and subsequently applied on a structural phantom and in vivo head measurements. Image artifacts were successfully suppressed by applying the GSTF-based pre-emphasis. Equivalent results are achieved with images acquired using GSTF-based post-correction of the trajectory as a part of image reconstruction. In contrast, the pre-emphasis approach allows reconstruction using the initially intended trajectory. The artifact suppression shown for two sequences demonstrates that the GSTF can serve for a novel pre-emphasis. A pre-emphasis based on the GSTF information can be applied to any arbitrary sequence type. © 2018 International Society for Magnetic Resonance in Medicine.

  1. 77 FR 56856 - National Institute on Aging; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-14

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's....S.C. App.), notice is hereby given of the following meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C...

  2. Temporal bone changes in patients with Goldenhar syndrome with special emphasis on inner ear abnormalities.

    PubMed

    Hennersdorf, Florian; Friese, Natascha; Löwenheim, Hubert; Tropitzsch, Anke; Ernemann, Ulrike; Bisdas, Sotirios

    2014-06-01

    Goldenhar syndrome is a developmental disorder presenting with orofacial and vertebral anomalies, which are also accompanied by abnormalities in other organs. We examined temporal bone changes with special emphasis on inner ear abnormalities in these patients. A retrospective review of 7 new cases in addition to a previously published series of 14 cases with clinically diagnosed Goldenhar syndrome was carried out to search for inner ear anomalies. In addition, temporal bone imaging studies from the literature were summarized and compared with our results. Departments of Neuroradiology and Otorhinolaryngology at a university hospital. In addition to the previous series of 14 patients, 7 new patients with Goldenhar syndrome were identified. Patients underwent otologic examination, audiometric studies, and high-resolution computed tomography (CT) or magnetic resonance imaging (MRI) of the temporal bone. Temporal bone changes and specifically inner ear malformations. Nineteen of 21 patients showed changes of the external and middle ear correlating with the literature. Seven of 21 patients showed inner ear abnormalities constituting one-third of all patients. These ranged from mild such as vestibular enlargement to severe defects such as cochlear hypoplasia and common cavity. Inner ear abnormalities were present in one-third of patients. Although in some cases, these might not be of clinical significance, some patients show severe defects of the inner ear requiring more complex hearing loss therapy. Therefore, imaging of the temporal bone structures is important in the care of these patients.

  3. The Hallmarks of Aging

    PubMed Central

    López-Otín, Carlos; Blasco, Maria A.; Partridge, Linda; Serrano, Manuel; Kroemer, Guido

    2013-01-01

    Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. This deterioration is the primary risk factor for major human pathologies including cancer, diabetes, cardiovascular disorders, and neurodegenerative diseases. Aging research has experienced an unprecedented advance over recent years, particularly with the discovery that the rate of aging is controlled, at least to some extent, by genetic pathways and biochemical processes conserved in evolution. This review enumerates nine tentative hallmarks that represent common denominators of aging in different organisms, with special emphasis on mammalian aging. These hallmarks are: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication. A major challenge is to dissect the interconnectedness between the candidate hallmarks and their relative contribution to aging, with the final goal of identifying pharmaceutical targets to improve human health during aging with minimal side-effects. PMID:23746838

  4. Software Acquisition in the Age of Cyber Warfare

    DTIC Science & Technology

    2011-05-01

    s c h o o l o f S Y S T E M S a n d L O G I S T I C S education service research Software Acquisition in the Age of Cyber Warfare Maj...DATE MAY 2011 2. REPORT TYPE 3. DATES COVERED 00-00-2011 to 00-00-2011 4. TITLE AND SUBTITLE Software Acquisition in the Age of Cyber Warfare 5a...AFIT Cyber 200/300 Courses Cyber Warfare IDE Program 34 Special Emphasis On… Enterprise Integration (Active Directory, PKI) Security

  5. 78 FR 5189 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-24

    ...: National Institute on Aging Special Emphasis Panel; Drug Development for Alzheimer's Disease. Date: March... U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C...

  6. 77 FR 24728 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... Institute on Aging Special Emphasis Panel; Drug Development for Alzheimer's Disease. Date: May 24, 2012... U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C...

  7. 77 FR 9670 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-17

    ... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Alzheimer's... U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C...

  8. The pathophysiology of monosymptomatic nocturnal enuresis with special emphasis on the circadian rhythm of renal physiology.

    PubMed

    Dossche, L; Walle, J Vande; Van Herzeele, C

    2016-06-01

    Nocturnal polyuria in monosymptomatic nocturnal enuresis (MNE) has so far mainly been attributed to a disturbed circadian rhythm of renal water handling. Low vasopressin levels overnight correlate with absent maximal concentrating activity, resulting in an increased nocturnal diuresis with low urinary osmolality. Therefore, treatment with desmopressin is a rational choice. Unfortunately, 20 to 60 % of children with monosymptomatic enuresis are desmopressin-resistant. There is increasing evidence that other disturbed circadian rhythms might play a role in nocturnal polyuria. This review focuses on renal aspects in the pathophysiology of nocturnal polyuria in MNE, with special emphasis on circadian rhythms. Articles related to renal circadian rhythms and enuresis were searched through the PubMed library with the goal of providing a concise review. Nocturnal polyuria can only partially be explained by blunted circadian rhythm of vasopressin secretion. Other alterations in the intrinsic renal circadian clock system also seem to be involved, especially in desmopressin-resistant enuresis. • Disturbance in the circadian rhythm of arginine vasopressin secretion is related to nocturnal polyuria in children with enuresis. • Desmopressin is recommended as a treatment for monosymptomatic nocturnal enuresis, working as a vasopressin analogue acting on V2 receptors in the collecting ducts of the kidney. What is New: • Other renal circadian rhythms might play a role in nocturnal polyuria, especially in desmopressin-resistant case.

  9. School-Age Test Proficiency and Special Education after Congenital Heart Disease Surgery in Infancy

    PubMed Central

    Mulkey, Sarah B.; Bai, Shasha; Luo, Chunqiao; Cleavenger, Jordyn E.; Gibson, Neal; Holland, Greg; Mosley, Bridget S.; Kaiser, Jeffrey R.; Bhutta, Adnan T.

    2016-01-01

    Objective To evaluate test proficiency and the receipt of special education services in school-age children who had surgery for congenital heart disease (CHD) <1 year of age. Study design Data from Arkansas-born children who had CHD surgery at Arkansas Children's Hospital at <1 year of age from 1996–2004 were linked to state birth certificates and the Arkansas Department of Education longitudinal database containing achievement test scores in literacy and mathematics for grades 3-4 and special education codes. The primary negative outcome was not achieving grade-level proficiency on achievement tests. Logistic regression accounting for repeated measures associated achieving proficiency with demographics, maternal education, and clinical factors. Results 362 of 458 (79%) children who received surgery for CHD matched to the ADE database; 285 had grade 3 and/or 4 achievement tests scores. Fewer students with CHD achieved proficiency in literacy and mathematics (P < .05) compared with grade-matched state students. Higher 5-minute Apgar score, shorter hospitalization, and higher maternal education predicted proficiency in literacy (P < .05). White race, no cardiopulmonary bypass, and shorter hospitalization predicted proficiency in mathematics (P < .05). Sex, gestational age, age at surgery, CHD diagnosis, and type and number of surgeries did not predict test proficiency. Compared with all public school students, more children with CHD received special education services (26.9% vs 11.6%, P < .001). Conclusion Children with CHD had poorer academic achievement and were more likely to receive special education services than all state students. Results from this study support the need for neurodevelopmental evaluations as standard in children with CHD. PMID:27453376

  10. Functional Curriculum for Elementary, Middle, and Secondary Age Students with Special Needs. Second Edition

    ERIC Educational Resources Information Center

    Wehman, Paul; Kregel, John

    2004-01-01

    The second edition of Functional Curriculum for Elementary, Middle, and Secondary Age Students with Special Needs has an expanded framework for a functional and longitudinal curriculum for children and adolescents with disabilities and other special needs. These is a stronger demand than ever to provide a curriculum with everyday usefulness and…

  11. Treatment of antimony mine drainage: challenges and opportunities with special emphasis on mineral adsorption and sulfate reducing bacteria.

    PubMed

    Li, Yongchao; Hu, Xiaoxian; Ren, Bozhi

    2016-01-01

    The present article summarizes antimony mine distribution, antimony mine drainage generation and environmental impacts, and critically analyses the remediation approach with special emphasis on iron oxidizing bacteria and sulfate reducing bacteria. Most recent research focuses on readily available low-cost adsorbents, such as minerals, wastes, and biosorbents. It is found that iron oxides prepared by chemical methods present superior adsorption ability for Sb(III) and Sb(V). However, this process is more costly and iron oxide activity can be inhibited by plenty of sulfate in antimony mine drainage. In the presence of sulfate reducing bacteria, sulfate can be reduced to sulfide and form Sb(2)S(3) precipitates. However, dissolved oxygen and lack of nutrient source in antimony mine drainage inhibit sulfate reducing bacteria activity. Biogenetic iron oxide minerals from iron corrosion by iron-oxidizing bacteria may prove promising for antimony adsorption, while the micro-environment generated from iron corrosion by iron oxidizing bacteria may provide better growth conditions for symbiotic sulfate reducing bacteria. Finally, based on biogenetic iron oxide adsorption and sulfate reducing bacteria followed by precipitation, the paper suggests an alternative treatment for antimony mine drainage that deserves exploration.

  12. Leadership in Early Childhood Special Education

    ERIC Educational Resources Information Center

    Arora, Samita Berry

    2013-01-01

    With the demands of high quality early childhood special education programs within public school settings, there is a need to place emphasis on research and training regarding early childhood leaders and managers in this complex and diverse field. The focus of this research is to examine what early childhood special education (ECSE) leadership…

  13. 38 CFR 6.15 - Cash value; special endowment at age 96 plan policy.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... endowment at age 96 plan policy. 6.15 Section 6.15 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS UNITED STATES GOVERNMENT LIFE INSURANCE Cash Value § 6.15 Cash value; special endowment at age 96 plan policy. Provisions for cash value shall become effective at the completion of the first...

  14. 75 FR 18513 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-12

    ... Institute on Aging Special Emphasis Panel; Early Alzheimer's Disease. Date: May 19, 2010. Time: 2 p.m. to 5... U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C...

  15. School-Age Test Proficiency and Special Education After Congenital Heart Disease Surgery in Infancy.

    PubMed

    Mulkey, Sarah B; Bai, Shasha; Luo, Chunqiao; Cleavenger, Jordyn E; Gibson, Neal; Holland, Greg; Mosley, Bridget S; Kaiser, Jeffrey R; Bhutta, Adnan T

    2016-11-01

    To evaluate test proficiency and the receipt of special education services in school-age children who had undergone surgery for congenital heart disease (CHD) at age <1 year. Data from Arkansas-born children who underwent surgery for CHD at Arkansas Children's Hospital at age <1 year between 1996 and 2004 were linked to state birth certificates and the Arkansas Department of Education longitudinal database containing achievement test scores in literacy and mathematics for grades 3-4 and special education codes. The primary negative outcome was not achieving grade-level proficiency on achievement tests. Logistic regression accounting for repeated measures was used to evaluate for associations between achieving proficiency and demographic data, maternal education, and clinical factors. A total of 362 of 458 (79%) children who underwent surgery for CHD were matched to the Arkansas Department of Education database, 285 of whom had grade 3 and/or 4 achievement tests scores. Fewer students with CHD achieved proficiency in literacy and mathematics (P < .05) compared with grade-matched state students. Higher 5-minute Apgar score, shorter duration of hospitalization, and higher maternal education predicted proficiency in literacy (P < .05). White race, no cardiopulmonary bypass, and shorter hospitalization predicted proficiency in mathematics (P < .05). Sex, gestational age, age at surgery, CHD diagnosis, and type and number of surgeries did not predict test proficiency. Compared with all public school students, more children with CHD received special education services (26.9% vs 11.6%; P < .001). Children with CHD had poorer academic achievement and were more likely to receive special education services than all state students. Results from this study support the need for neurodevelopmental evaluations as standard practice in children with CHD. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. Brain Specialization Research and the Teaching of Nonverbal Communication.

    ERIC Educational Resources Information Center

    Jensen, Marvin D.

    1980-01-01

    The connectionist theory of brain functioning, which holds that specialization exists within the brain, has three implications for teachers of nonverbal communication. One implication involves the relative emphasis to be placed on linguistic/linear versus nonlinguistic/nonlinear mental processing. Teachers can shift emphasis to nonlinguistic…

  17. Biogeography in Cellana (Patellogastropoda, Nacellidae) with Special Emphasis on the Relationships of Southern Hemisphere Oceanic Island Species.

    PubMed

    González-Wevar, Claudio A; Nakano, Tomoyuki; Palma, Alvaro; Poulin, Elie

    2017-01-01

    Oceanic islands lacking connections to other land are extremely isolated from sources of potential colonists and have acquired their biota mainly through dispersal from geographically distant areas. Hence, isolated island biota constitutes interesting models to infer biogeographical mechanisms of dispersal, colonization, differentiation, and speciation. Limpets of the genus Cellana (Nacellidae: Patellogastropoda) show limited dispersal capacity but are broadly distributed across the Indo-Pacific including many endemic species in isolated oceanic islands. Here, we examined main distributional patterns and geographic boundaries among Cellana lineages with special emphasis in the relationships of Southern Hemisphere oceanic islands species. Phylogenetic reconstructions based on mtDNA (COI) recognized three main clades in Cellana including taxa from different provinces of the Indo-Pacific. Clear genetic discontinuities characterize the biogeography of Cellana and several lineages are associated to particular areas of the Indo-Pacific supporting the low dispersal capacity of the genus across recognized biogeographical barriers in the region. However, evolutionary relationships within Cellana suggest that long-distance dispersal processes have been common in the history of the genus and probably associated to the origin of the species in Hawaii and Juan Fernández Archipelago. Therefore, the presence of Cellana species in geographically distant Southern Hemisphere oceanic islands, such as the Juan Fernández Archipelago, suggests that long-distance dispersal mediated by rafting may have played an important role in the biogeography of the genus.

  18. Virtues and Well-Being of Korean Special Education Teachers

    ERIC Educational Resources Information Center

    Kim, So-Young; Lim, Young-Jin

    2016-01-01

    Although much emphasis has been paid to stress and burnout among special education teachers, little attention has been paid to their well-being. This study aimed to examine relations between virtues and well-being among Korean special education teachers. Virtues and well-being of 115 Korean special education teachers were assessed using the…

  19. Who gets a mammogram amongst European women aged 50-69 years?

    PubMed Central

    2012-01-01

    On the basis of the Survey of Health, Ageing, and Retirement (SHARE), we analyse the determinants of who engages in mammography screening focusing on European women aged 50-69 years. A special emphasis is put on the measurement error of subjective life expectancy and on the measurement and impact of physician quality. Our main findings are that physician quality, better education, having a partner, younger age and better health are associated with higher rates of receipt. The impact of subjective life expectancy on screening decision substantially increases after taking measurement error into account. JEL Classification C 36, I 11, I 18 PMID:22828268

  20. A Brief Measure of Language Skills at 3 Years of Age and Special Education Use in Middle Childhood.

    PubMed

    McIntyre, Laura Lee; Pelham, William E; Kim, Matthew H; Dishion, Thomas J; Shaw, Daniel S; Wilson, Melvin N

    2017-02-01

    To test whether a language screener administered during early childhood predicts special education referrals and placement in middle childhood. A series of logistic regressions was conducted in a longitudinal study of 731 children. Predictor variables included scores on the early language screener (Fluharty Preschool Speech and Language Screening Test-Second Edition [Fluharty-2]) at ages 3 and 4 years, a standardized measure of academic achievement at age 5 years, and parent report of special education services at ages 7.5, 8.5, and 9.5 years. Results showed that higher scores on the Fluharty-2 predicted a reduced likelihood of having an individualized education program (OR 0.48), being referred for special education (OR 0.55), and being held back a grade (OR 0.37). These findings did not vary by sex, race, or ethnicity, and remained significant after controlling for male sex, behavior problems, parental education, and family income. The Fluharty-2 remained predictive of special education outcomes even after controlling for children's academic skills at age 5 years. Results suggest that structured, brief assessments of language in early childhood are robust predictors of children's future engagement in special education services and low academic achievement. Primary care physicians may use a multipronged developmental surveillance and monitoring protocol designed to identify children who may need comprehensive evaluation and intervention. Early intervention may reduce the need for costly special education services in the future and reduce comorbid conditions. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. Special Education in Canada: Past, Present and Future.

    ERIC Educational Resources Information Center

    Hodder, Clive

    The paper reviews the history and present status of special education in Canada (with particular emphasis on the province of Ontario) and identifies recommended future directions. The legislative authority for special education and current policies are summarized in sections on the following provinces: British Columbia, Alberta, Saskatchewan,…

  2. Biogeography in Cellana (Patellogastropoda, Nacellidae) with Special Emphasis on the Relationships of Southern Hemisphere Oceanic Island Species

    PubMed Central

    Nakano, Tomoyuki; Palma, Alvaro; Poulin, Elie

    2017-01-01

    Oceanic islands lacking connections to other land are extremely isolated from sources of potential colonists and have acquired their biota mainly through dispersal from geographically distant areas. Hence, isolated island biota constitutes interesting models to infer biogeographical mechanisms of dispersal, colonization, differentiation, and speciation. Limpets of the genus Cellana (Nacellidae: Patellogastropoda) show limited dispersal capacity but are broadly distributed across the Indo-Pacific including many endemic species in isolated oceanic islands. Here, we examined main distributional patterns and geographic boundaries among Cellana lineages with special emphasis in the relationships of Southern Hemisphere oceanic islands species. Phylogenetic reconstructions based on mtDNA (COI) recognized three main clades in Cellana including taxa from different provinces of the Indo-Pacific. Clear genetic discontinuities characterize the biogeography of Cellana and several lineages are associated to particular areas of the Indo-Pacific supporting the low dispersal capacity of the genus across recognized biogeographical barriers in the region. However, evolutionary relationships within Cellana suggest that long-distance dispersal processes have been common in the history of the genus and probably associated to the origin of the species in Hawaii and Juan Fernández Archipelago. Therefore, the presence of Cellana species in geographically distant Southern Hemisphere oceanic islands, such as the Juan Fernández Archipelago, suggests that long-distance dispersal mediated by rafting may have played an important role in the biogeography of the genus. PMID:28099466

  3. Policy Challenges and Opportunities for Rural Special Education

    ERIC Educational Resources Information Center

    Rude, Harvey; Miller, Kevin J.

    2018-01-01

    This article reviews current developments in state and national policies that affect rural special education. A brief overview of the federal role in rural education is provided, with emphasis on the implications for the provision of special education services in rural communities. A variety of challenges are identified, including (a) the variable…

  4. Guide to Special Information in Scientific and Engineering Journals.

    ERIC Educational Resources Information Center

    Harris, Mary Elizabeth

    This annotated bibliography lists 203 special features or special issues of science and technology periodicals with emphasis on compilations of information that appear in periodicals on a regular basis. Subjects covered in the guide include aeronautics, air-conditioning and refrigeration engineering, astronomy, automobiles, biology, botany,…

  5. A review of Brucella infection in marine mammals, with special emphasis on Brucella pinnipedialis in the hooded seal (Cystophora cristata)

    PubMed Central

    2011-01-01

    Brucella spp. were isolated from marine mammals for the first time in 1994. Two novel species were later included in the genus; Brucella ceti and Brucella pinnipedialis, with cetaceans and seals as their preferred hosts, respectively. Brucella spp. have since been isolated from a variety of marine mammals. Pathological changes, including lesions of the reproductive organs and associated abortions, have only been registered in cetaceans. The zoonotic potential differs among the marine mammal Brucella strains. Many techniques, both classical typing and molecular microbiology, have been utilised for characterisation of the marine mammal Brucella spp. and the change from the band-based approaches to the sequence-based approaches has greatly increased our knowledge about these strains. Several clusters have been identified within the B. ceti and B. pinnipedialis species, and multiple studies have shown that the hooded seal isolates differ from other pinniped isolates. We describe how different molecular methods have contributed to species identification and differentiation of B. ceti and B. pinnipedialis, with special emphasis on the hooded seal isolates. We further discuss the potential role of B. pinnipedialis for the declining Northwest Atlantic hooded seal population. PMID:21819589

  6. Intestinal polyparasitism with special emphasis to soil-transmitted helminths among residents around Gilgel Gibe Dam, Southwest Ethiopia: a community based survey.

    PubMed

    Mekonnen, Zeleke; Suleman, Sultan; Biruksew, Abdissa; Tefera, Tamirat; Chelkeba, Legese

    2016-11-23

    One third of the world population is estimated to be infected with intestinal parasites. The most affected people are children and the poor people living in tropics and subtropics. Polyparasitism (the concurrent infection with multiple intestinal parasite species) is found to be the norm among the same population although accurate estimate of its magnitude is unknown. It was found that polyparasitism might have a greater impact on morbidity than single species infection which might also increase susceptibility to other infections. Therefore, this study aimed at determining the prevalence and distribution of intestinal polyparasitism with special emphasis on Soil-Transmitted Helminths (STH) among residents around Gilgel Gibe dam located in Jimma zone of Oromia regional state, Ethiopia. A total of 1,021 participants were recruited in this study and provided stool samples for parasitological examination. Direct wet mount and Kato-Katz techniques were employed for stool examination. Pearson chi-square test was employed to assess the association of infection status and polyparasitism with gender and age group of the study participants. Five hundred thirty two individuals were infected with at least one parasite, providing the overall prevalence of 52.1%. Among positive individuals, 405 (76.1%), 114 (21.4%), and 13 (2.5%) individuals were infected with only one, two and three species of parasites, respectively. The overall prevalence of intestinal polyparasitism observed among the study participants was 12.4% (127/1,021). The predominant STH was hookworm, with a prevalence of 44.1%. Hookworm and Ascaris lumbricoides were the most frequently recorded combination in cases of polyparasitic infection. The study revealed that there was no significant difference in the distribution of polyparasitism with regard to age group and sex of the study participants (p > 0.05). The study indicated the presence of high prevalence of parasites as well as distribution of

  7. Developments in Aging: 1989. Volume 1. A Report of the Special Committee on Aging, United States Senate, Pursuant to S. RES. 66, SEC. 19, February 28, 1989, Resolution Authorizing a Study of the Problems of the Aged and Aging. 101st Congress, 2d Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    This document contains the 1989 annual report of the Senate Special Committee on Aging. It describes actions during 1989 by the Congress, the federal administration, and the U.S. Senate Special Committee on Aging, which are significant to America's older citizens. It also summarizes and analyzes the federal policies and programs that are of the…

  8. Aging and social expenditures in Italy: some issues associated with population projections.

    PubMed

    Terra Abrami, V

    1990-01-01

    "After describing the main results of the recent Italian population projections, and some possible consequences...aging may have on social expenditures, this paper focuses on attempts to improve the accuracy of development assumptions, with special regard to natural components. Emphasis is placed on the importance of applying specific methodological tools to define self-explanatory assumptions for fertility and mortality and to produce projections which could be considered, with reasonable limitations, as real forecasts." excerpt

  9. Special Education through Neighbourhood Centers in Algeria.

    ERIC Educational Resources Information Center

    Boucebci, Mahfoud

    1981-01-01

    The article provides a survey of special education needs in Algeria with emphasis on the role of neighborhood centers which involve parents in the education of mentally handicapped children. Journal availability: see EC 133 861. (DB)

  10. A synopsis on aging-Theories, mechanisms and future prospects.

    PubMed

    da Costa, João Pinto; Vitorino, Rui; Silva, Gustavo M; Vogel, Christine; Duarte, Armando C; Rocha-Santos, Teresa

    2016-08-01

    Answering the question as to why we age is tantamount to answering the question of what is life itself. There are countless theories as to why and how we age, but, until recently, the very definition of aging - senescence - was still uncertain. Here, we summarize the main views of the different models of senescence, with a special emphasis on the biochemical processes that accompany aging. Though inherently complex, aging is characterized by numerous changes that take place at different levels of the biological hierarchy. We therefore explore some of the most relevant changes that take place during aging and, finally, we overview the current status of emergent aging therapies and what the future holds for this field of research. From this multi-dimensional approach, it becomes clear that an integrative approach that couples aging research with systems biology, capable of providing novel insights into how and why we age, is necessary. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. Guide to Special Information in Scientific and Engineering Journals.

    ERIC Educational Resources Information Center

    Harris, Mary Elizabeth

    This update of a 1983 annotated bibliography lists 298 special features or special issues of science and technology periodicals with emphasis on compilations of information that appear in periodicals on a regular basis. In addition to the 203 entries listed in the original edition, 95 new entries are included. Subjects covered in the guide include…

  12. Introduction and overview of the special issue "Brain imaging and aging": The new era of neuroimaging in aging research.

    PubMed

    Furukawa, Katsutoshi; Ishiki, Aiko; Tomita, Naoki; Onaka, Yuta; Saito, Haruka; Nakamichi, Tomoko; Hara, Kazunari; Kusano, Yusuke; Ebara, Masamune; Arata, Yuki; Sakota, Miku; Miyazawa, Isabelle; Totsune, Tomoko; Okinaga, Shoji; Okamura, Nobuyuki; Kudo, Yukitsuka; Arai, Hiroyuki

    2016-09-01

    It is well known that the brain is one of the organs particularly affected by aging in terms of function, relative to the gastrointestinal tract and liver, which exhibit less functional decline. There is also a wide range of age-related neurological disorders such as stroke, Alzheimer's disease, and Parkinson's disease. Therefore, it is very important to understand the relationship between functional age-related change and neurological dysfunction. Neuroimaging techniques including magnetic resonance imaging and positron emission tomography have been significantly improved over recent years. Many physicians and researchers have investigated various mechanisms of age-related cerebral change and associated neurological disorders using neuroimaging techniques. In this special issue of Ageing Research Reviews, we focus on cerebral- and neuro-imaging, which are a range of tools used to visualize structure, functions, and pathogenic molecules in the nervous system. In addition, we summarize several review articles about the history, present values, and future perspectives of neuroimaging modalities. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. Attention Deficit Hyperactivity Disorder: Special Education Policy and Practice in Australia.

    ERIC Educational Resources Information Center

    Prosser, Brenton; Reid, Robert; Shute, Rosalyn; Atkinson, Ivan

    2002-01-01

    Outlines Australian special education policy and practice regarding Attention Deficit Hyperactivity Disorder (ADHD) in public schools. Drawing on U.S. comparisons, considers how recent government legislation may have made the label "disability" appear pragmatic to those seeking special education assistance. Proposes that an emphasis on…

  14. Markers of Oxidant Stress that are Clinically Relevant in Aging and Age-related Disease

    PubMed Central

    Jacob, Kimberly D.; Hooten, Nicole Noren; Trzeciak, Andrzej R.; Evans, Michele K.

    2013-01-01

    Despite the long held hypothesis that oxidant stress results in accumulated oxidative damage to cellular macromolecules and subsequently to aging and age-related chronic disease, it has been difficult to consistently define and specifically identify markers of oxidant stress that are consistently and directly linked to age and disease status. Inflammation because it is also linked to oxidant stress, aging, and chronic disease also plays an important role in understanding the clinical implications of oxidant stress and relevant markers. Much attention has focused on identifying specific markers of oxidative stress and inflammation that could be measured in easily accessible tissues and fluids (lymphocytes, plasma, serum). The purpose of this review is to discuss markers of oxidant stress used in the field as biomarkers of aging and age-related diseases, highlighting differences observed by race when data is available. We highlight DNA, RNA, protein, and lipid oxidation as measures of oxidative stress, as well as other well-characterized markers of oxidative damage and inflammation and discuss their strengths and limitations. We present the current state of the literature reporting use of these markers in studies of human cohorts in relation to age and age-related disease and also with a special emphasis on differences observed by race when relevant. PMID:23428415

  15. Developments in Aging: 1989. Volume 2--Appendixes. A Report of the Special Committee on Aging, United States Senate, Pursuant to S. RES. 66, SEC. 19, February 28, 1989, Resolution Authorizing a Study of the Problems of the Aged and Aging. 101st Congress, 2d Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    This document contains the appendices to the 1989 annual report of the Senate Special Committee on Aging which: (1) describes actions during 1989 by the Congress, the federal administration, and the U.S. Senate Special Committee on Aging, that are significant to America's older citizens; and (2) summarizes and analyzes the federal policies and…

  16. Childhood growth and development associated with need for full-time special education at school age.

    PubMed

    Mannerkoski, Minna; Aberg, Laura; Hoikkala, Marianne; Sarna, Seppo; Kaski, Markus; Autti, Taina; Heiskala, Hannu

    2009-01-01

    To explore how growth measurements and attainment of developmental milestones in early childhood reflect the need for full-time special education (SE). After stratification in this population-based study, 900 pupils in full-time SE groups (age-range 7-16 years, mean 12 years 8 months) at three levels and 301 pupils in mainstream education (age-range 7-16, mean 12 years 9 months) provided data on height and weight from birth to age 7 years and head circumference to age 1 year. Developmental screening was evaluated from age 1 month to 48 months. Statistical methods included a general linear model (growth measurements), binary logistic regression analysis (odds ratios for growth), and multinomial logistic regression analysis (odds ratios for developmental milestones). At 1 year, a 1 standard deviation score (SDS) decrease in height raised the probability of SE placement by 40%, and a 1 SDS decrease in head size by 28%. In developmental screening, during the first months of life the gross motor milestones, especially head support, differentiated the children at levels 0-3. Thereafter, the fine motor milestones and those related to speech and social skills became more important. Children whose growth is mildly impaired, though in the normal range, and who fail to attain certain developmental milestones have an increased probability for SE and thus a need for special attention when toddlers age. Similar to the growth curves, these children seem to have consistent developmental curves (patterns).

  17. Boxed In: An Explanation for the Growth of Special Education.

    ERIC Educational Resources Information Center

    Ruediger, Greg; Lorance, Anne Gates

    Noting that the number of students served in special education programs has increased at alarming rates since 1975, this paper posits that this increase is due to recent social and political variables and their impact on the educational system. Special emphasis is placed on how state and local educational leaders respond to national education…

  18. A comprehensive morphometric analysis of the internal thoracic artery with emphasis on age, gender and left-to-right specific differences.

    PubMed

    Borović, Milica Labudovi; Borović, Saša; Marinković-Erić, Jelena; Todorović, Vera; Puškaš, Nela; Kočica, Mladen; Radak, Đorđe; Lačković, Vesna

    2013-10-01

    The aim of this analysis was the morphometric description of the internal thoracic artery (ITA) with an emphasis on age, gender and left-to-right specific differences, as well as on age and atherosclerosis related changes of the elastic skeleton. Forty eight arteries were obtained during forensic autopsies from 32 persons who had died of non-vascular causes. The following morphometric parameters were analyzed: thickness of the intima, the medial layer and the wall, the intima-to media-ratio and the elastic skeleton parameters. The intima thickness increases significantly with aging (ANOVA F=34.061, p⟨0.001), as does the intima-to-media ratio (ANOVA F=10.831, p⟨0.001). With aging, there is a significant increase in the thickness of the media (F=56.519; p⟨0.001) and of the wall (F=34.094; p⟨0,001). There is a significant increase in the media thickness during the development of atherosclerosis in the ITA (ANOVA F=11.848, p⟨0.001). No significant difference was found when these data were analyzed based on the left-to-right principle or depending on gender of the patients. However, the analysis of the elastic skeleton parameters indicated that the combined effects of aging, atherosclerosis and male gender lead to the degeneration of the elastic skeleton of the ITA. The grade of atherosclerosis gradually increases with aging as shown by morphometric analysis. The increase in the medial layer thickness suggests the potential for positive remodeling of the ITA during aging and atherosclerosis. The left/right position has no influence on morphometric parameters of the ITA, while male gender affects parameters of the elastic skeleton.

  19. The regeneration of central hardwoods with emphasis on the effects of site quality and harvesting practice

    Treesearch

    G. R., Jr. Trimble

    1973-01-01

    This report is an attempt to integrate and summarize research results from studies made mostly in West Virginia and to show the relationship of site quality and cutting practices to hardwood reproduction, with special emphasis on species composition. Reproduction has been found satisfactory in numbers and distribution after both clearcutting and selection cutting, but...

  20. Cultural, Socio-Economic and Political Influences on Special Education in Nigeria.

    ERIC Educational Resources Information Center

    Obiakor, Festus E.

    The paper describes the present state of education in Nigeria with emphasis on the cultural, socio-economic, and political influences affecting special education. After a brief summary of education in Nigeria since independence (1960), the paper looks at problems identified in special education and at Section 8, that portion of the National Policy…

  1. Preventive dental health care experiences of preschool-age children with special health care needs.

    PubMed

    Huebner, Colleen E; Chi, Donald L; Masterson, Erin; Milgrom, Peter

    2015-01-01

    This study examined the preventive dental health care experiences of young children with special needs and determined the feasibility of conducting clinical dental examinations at a community-based early intervention services center. Study methods included 90 parent interviews and dental examinations of their preschool-age children. Thirteen percent of the children received optimal preventive care, defined as twice daily tooth brushing with fluoridated toothpaste and two preventive dental visits in the prior 12 months; 37% experienced care that fell short in both areas. Optimal care was more common among children of parents who reported tooth brushing was not a struggle and those with a personal dentist. Parents' opinion of the study experience was generally positive. Few children with special needs receive effective preventive care early, when primary prevention could be achieved. Barriers to optimal care could be readily addressed by the dental community in coordination with early intervention providers. © 2014 Special Care Dentistry Association and Wiley Periodicals, Inc.

  2. Quantitative estimates of dietary intake with special emphasis on snacking pattern and nutritional status of free living adults in urban slums of Delhi: impact of nutrition transition

    PubMed Central

    Singh, Archna; Gupta, Vidhu; Ghosh, Arpita; Lock, Karen; Ghosh-Jerath, Suparna

    2016-01-01

    Background The nutritional landscape of India is experiencing the fallout of urbanization and globalization. The changes are manifest in dietary patterns as well as health outcomes. The study aimed at assessing household dietary intake pattern with special emphasis on snacking pattern, anthropometric and lipid profiles in low socio-economic status households in an urban slum of Delhi. Methods Community based cross-sectional study in 260 households of a purposively selected urban slum in North-East district of Delhi, India. Family dietary surveys including consumption pattern of commercial food products rich in Partially Hydrogenated Vegetable Oils (PHVOs), 24 h dietary recall and assessment of dietary diversity using Household Diet Diversity Scores (HDDS) were done. Assessment of nutritional status using anthropometric and lipid profile on a subsample (n =130) were also conducted. Results Median energy and fat intake were adequate. Micronutrient intake was found to be inadequate for vitamin A, riboflavin, calcium and folate. PHVO usage was low (<20 % households). Milk (39 %), green leafy vegetables (25 %) and fruits (25 %) intake were below recommendations. Mean HDDS was 7.87. Prevalence of overweight/obesity was high (66.7 %). Lipid profile showed mean HDL-C levels lower than recommendations for females. Conclusion Community based awareness programs for prevention of non-communicable diseases should incorporate healthy diet and lifestyle practices with emphasis on quantity and quality of nutrient intake. This must be considered as an integral part of chronic disease prevention strategy for underprivileged communities in urban India. PMID:26918196

  3. Quantitative estimates of dietary intake with special emphasis on snacking pattern and nutritional status of free living adults in urban slums of Delhi: impact of nutrition transition.

    PubMed

    Singh, Archna; Gupta, Vidhu; Ghosh, Arpita; Lock, Karen; Ghosh-Jerath, Suparna

    2015-10-14

    The nutritional landscape of India is experiencing the fallout of urbanization and globalization. The changes are manifest in dietary patterns as well as health outcomes. The study aimed at assessing household dietary intake pattern with special emphasis on snacking pattern, anthropometric and lipid profiles in low socio-economic status households in an urban slum of Delhi. Community based cross-sectional study in 260 households of a purposively selected urban slum in North-East district of Delhi, India. Family dietary surveys including consumption pattern of commercial food products rich in Partially Hydrogenated Vegetable Oils (PHVOs), 24 h dietary recall and assessment of dietary diversity using Household Diet Diversity Scores (HDDS) were done. Assessment of nutritional status using anthropometric and lipid profile on a subsample ( n =130) were also conducted. Median energy and fat intake were adequate. Micronutrient intake was found to be inadequate for vitamin A, riboflavin, calcium and folate. PHVO usage was low (<20 % households). Milk (39 %), green leafy vegetables (25 %) and fruits (25 %) intake were below recommendations. Mean HDDS was 7.87. Prevalence of overweight/obesity was high (66.7 %). Lipid profile showed mean HDL-C levels lower than recommendations for females. Community based awareness programs for prevention of non-communicable diseases should incorporate healthy diet and lifestyle practices with emphasis on quantity and quality of nutrient intake. This must be considered as an integral part of chronic disease prevention strategy for underprivileged communities in urban India.

  4. 76 FR 64090 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-17

    ... Special Emphasis Panel, Oxidative Stress, Aging, and Transmitters. Date: November 9-10, 2011. Time: 8 a.m...: Center for Scientific Review Special Emphasis Panel, Fellowships: Physiology and Pathobiology of...

  5. Developments in Aging: 1986. Volume 1. A Report of the Special Committee on Aging. United States Senate, One Hundredth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    This document is the first volume of a two-volume Senate report describing actions taken during 1986 by the Congress, the administration, and the Senate Special Committee on Aging which are significant to older Americans. It summarizes and analyzes federal policies and programs that are of continuing importance for older persons and their…

  6. Biosynthesis of GPI-anchored proteins: special emphasis on GPI lipid remodeling

    PubMed Central

    Kinoshita, Taroh; Fujita, Morihisa

    2016-01-01

    Glycosylphosphatidylinositols (GPIs) act as membrane anchors of many eukaryotic cell surface proteins. GPIs in various organisms have a common backbone consisting of ethanolamine phosphate (EtNP), three mannoses (Mans), one non-N-acetylated glucosamine, and inositol phospholipid, whose structure is EtNP-6Manα-2Manα-6Manα-4GlNα-6myoinositol-P-lipid. The lipid part is either phosphatidylinositol of diacyl or 1-alkyl-2-acyl form, or inositol phosphoceramide. GPIs are attached to proteins via an amide bond between the C-terminal carboxyl group and an amino group of EtNP. Fatty chains of inositol phospholipids are inserted into the outer leaflet of the plasma membrane. More than 150 different human proteins are GPI anchored, whose functions include enzymes, adhesion molecules, receptors, protease inhibitors, transcytotic transporters, and complement regulators. GPI modification imparts proteins with unique characteristics, such as association with membrane microdomains or rafts, transient homodimerization, release from the membrane by cleavage in the GPI moiety, and apical sorting in polarized cells. GPI anchoring is essential for mammalian embryogenesis, development, neurogenesis, fertilization, and immune system. Mutations in genes involved in remodeling of the GPI lipid moiety cause human diseases characterized by neurological abnormalities. Yeast Saccharomyces cerevisiae has >60 GPI-anchored proteins (GPI-APs). GPI is essential for growth of yeast. In this review, we discuss biosynthesis of GPI-APs in mammalian cells and yeast with emphasis on the lipid moiety. PMID:26563290

  7. The Role of Special Education in an Overall Rehabilitation Program. Monograph Number Seven.

    ERIC Educational Resources Information Center

    Dyssegaard, Birgit

    The monograph addresses the place of special education in the continuum of rehabilitation services with particular emphasis on special education in Denmark and the United States. New Danish laws about services for handicapped people and their implications for such aspects as normalization, decentralization, and integration are reviewed and…

  8. Attitude of the Italian general population towards prevention and screening of the most common tumors, with special emphasis on colorectal malignancies.

    PubMed

    Domati, Federica; Travlos, Estratios; Cirilli, Claudia; Rossi, Giuseppina; Benatti, Piero; Marino, Massimiliano; Ponti, Giovanni; Vandelli, Maria; Valmori, Simone; Oursana, Amal; Pezzi, Annalisa; Ponz de Leon, Maurizio

    2009-06-01

    Screening and early diagnosis of cancer represent relatively recent tools in the long-lasting battle against tumors. If the American public opinion manifests its enthusiasm towards screening, the attitude of European is less well known. The purpose of the present study was to assess the level of knowledge and awareness of cancer screening (with particular emphasis on colorectal neoplasms) among middle-aged individuals. The study group consisted of 945 healthy individuals (489 men, 456 women, average age 57 +/- 12.4 years) who were asked to answer a series of questions about cancer screening and surveillance through a questionnaire presented by trained residents. Each interview lasted 20-30 min. Middle-aged Italians of both sexes seem to be aware of the fact that cancer is a frequent disease; moreover, many of the interviewed subjects believe almost all neoplasms are incurable. Diet, style of life, other environmental factors and familial factors are fully appreciated as relevant risk factors. The exact meaning of prevention was clear to less than half of the subjects. When various cancer sites were analyzed, the existence of preventive measures was well known for breast, cervical and prostate tumors, but their role was less clear for colorectal cancer. Only a fraction of the interviewed individuals were willing to undergo screening; the main reasons for refusal were lack of usefulness and fear of results. Among various tests, ultrasound and endoscopy were usually carried out in the presence of symptoms. Finally, multivariate analysis showed that the two factors significantly associated with the decision to undergo screening procedures were increasing age and level of education. The results of the study suggest that middle-aged Italian individuals, predominantly from Northern regions, have a correct perception of some aspects (frequency, risk factors) of cancer biology, whereas the knowledge of other aspects (outcome, prevention) remains poor or approximate. It

  9. Dying with Dignity: Difficult Times, Difficult Choices. A Report Presented by the Chairman of the Select Committee on Aging. House of Representatives, Ninety-Ninth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This report from the Select Committee on Aging examines financial, medical, and social issues surrounding terminally ill patients with special emphasis on the elderly terminally ill. The first section discusses topics related to the medical treatment of the terminally ill. Two basic issues are important: the right to have medical treatment and the…

  10. 38 CFR 6.14 - Cash value; other than special endowment at age 96 plan policy.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... special endowment at age 96 plan policy; all values, reserves, and net single premiums being based on the... shall be the reserve together with any dividend accumulations. For each month after the first policy year the reserve at the end of the preceding policy year shall be increased by one-twelfth of the...

  11. Research Forum on Changes in Sensory Perception in Middle-Aged Adults: A Summary of a Special Session at Hearing Across the Lifespan (HEAL) 2014.

    PubMed

    Humes, Larry E

    2015-06-01

    The purpose of this article is to introduce the special research forum on sensory-processing changes in middle-aged adults. This is a brief written introduction to the special session, which included five presentations, each emphasizing a slightly different aspect of sensory perception. The effects of aging on sensory processing, including auditory processing and speech perception, are not confined to older adults but begin in middle age in many cases.

  12. Microwave and Infrared Absorption Properties of Atmospheric Species with Special Emphasis on Line Widths and Shifts.

    DTIC Science & Technology

    1985-07-01

    studied pressure-broadening of the 110.8 GHz line of ozone (6 1 5 6 0 6) for the foreign gases N2 and 02. Considering a temper- ature range from 200...nitrogen and oxygen as tje perturbing gases . Calculations using * conventional Anderson theory or quantum Fourier transform theory2 are shown to be...one gases in the region from 0 to 10,000 cm-’. Emphasis on this edition has been on the addition of numerous millimeter and submillimeter transitions

  13. Linking Medicine & Education for the Child with Special Needs. What We Know...How We Teach. [Videotape].

    ERIC Educational Resources Information Center

    Buehler, Bruce

    This 34-minute videotape on meeting the special medical needs of children is intended for use in staff development with special educators, regular educators, and school nurses serving children with special health care needs in inclusive school settings. Emphasis is on linking "what we know" in the field of medicine to "how we…

  14. Integrated plant nutrient system - with special emphasis on mineral nutriton and biofertilizers for Black pepper and cardamom - A review.

    PubMed

    K P, Sangeeth; R, Suseela Bhai

    2016-05-01

    Integrated Plant Nutrition System (IPNS) as a concept and farm management strategy embraces and transcends from single season crop fertilization efforts to planning and management of plant nutrients in crop rotations and farming systems on a long-term basis for enhanced productivity, profitability and sustainability. It is estimated that about two-thirds of the required increase in crop production in developing countries will have to come from yield increases from lands already under cultivation. IPNS enhances soil productivity through a balanced use of soil nutrients, chemical fertilizers, combined with organic sources of plant nutrients, including bio-inoculants and nutrient transfer through agro-forestry systems and has adaptation to farming systems in both irrigated and rainfed agriculture. Horticultural crops, mainly plantation crops, management practices include application of fertilizers and pesticides which become inevitable due to the depletion of soil organic matter and incidence of pests and diseases. The extensive use of chemical fertilizers in these crops deteriorated soil health that in turn affected the productivity. To revitalize soil health and to enhance productivity, it is inexorable to enrich the soil using microorganisms. The lacunae observed here is the lack of exploitation of indigenous microbes having the potential to fix atmospheric nitrogen (N) and to solubilize Phosphorus (P) and Potassium (K). The concept of biofertilizer application appears to be technically simple and financially feasible, but the task of developing biofertilizers with efficient strains in appropriate combinations in a consortia mode is not easier. More than developing consortia, a suitable delivery system to discharge the microbial inoculants warranted much effort. This review focuses on the integrated plant nutrition system incorporating biofertilizer with special emphasis on developing and formulating biofertilizer consortium.

  15. Evaluation of the Specialized, Volunteer Transportation Program of the Area IV Agency on Aging and Community Service

    DOT National Transportation Integrated Search

    1987-08-01

    This report contains an evaluation of a specialized volunteer, rural : transportation program implemented in April of 1986. The Area IV Agency on : Aging and Community Services received a grant from the Urban Mass Transit : Administration for this pr...

  16. Effects of prenatal cocaine exposure on special education in school-aged children.

    PubMed

    Levine, Todd P; Liu, Jing; Das, Abhik; Lester, Barry; Lagasse, Linda; Shankaran, Seetha; Bada, Henrietta S; Bauer, Charles R; Higgins, Rosemary

    2008-07-01

    The objective of this study was to evaluate the effects of prenatal cocaine exposure on special education at age 7 with adjustment for covariates. As part of the prospective, longitudinal, multisite study of children with prenatal cocaine exposure (Maternal Lifestyle Study), school records were reviewed for 943 children at 7 years to determine involvement in special education outcomes: (1) individualized education plan; (2) special education conditions; (3) support services; (4) special education classes; and (5) speech and language services. Logistic regression was used to examine the effect of prenatal cocaine exposure on these outcomes with environmental, maternal, and infant medical variables as covariates, as well as with and without low child IQ. Complete data for each analysis model were available for 737 to 916 children. When controlling for covariates including low child IQ, prenatal cocaine exposure had a significant effect on individualized education plan. When low child IQ was not included in the model, prenatal cocaine exposure had a significant effect on support services. Male gender, low birth weight, white race, and low child IQ also predicted individualized education plan. Low birth weight and low child IQ were significant in all models. White race was also significant in speech and language services. Other covariate effects were model specific. When included in the models, low child IQ accounted for more of the variance and changed the significance of other covariates. Prenatal cocaine exposure increased the likelihood of receiving an individualized education plan and support services, with adjustment for covariates. Low birth weight and low child IQ increased the likelihood of all outcomes. The finding that white children were more likely to get an individualized education plan and speech and language services could indicate a greater advantage in getting educational resources for this population.

  17. The Affordances and Constraints of Special Education Initial Teacher Licensure Policy for Teacher Preparation

    ERIC Educational Resources Information Center

    Blanton, Linda P.; Boveda, Mildred; Munoz, Lorena R.; Pugach, Marleen C.

    2017-01-01

    Initial licensure polices in special education were examined to determine how these policies support or hinder reform efforts to develop teacher education programs that prepare graduates for the increasingly complex needs of diverse students. Initial special education licensure policies are described with an emphasis on the differences across…

  18. Developments in Aging: 1986--Volume 2--Appendixes. A Report of the Special Committee on Aging. United States Senate, One Hundredth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    This document is the second volume of a two-volume Senate report describing actions taken during 1986 by the Congress, the administration, and the Senate Special Committee on Aging which are significant to older Americans. While volume 1 summarizes and analyzes federal policies and programs that are of continuing importance for older persons and…

  19. High School Programs for Students with Special Needs.

    ERIC Educational Resources Information Center

    Lieman, Meyer, Ed.

    1980-01-01

    Thirteen brief articles look at high school programs for students with special needs with emphasis on programs offered in New York State. Articles have the following titles and authors: "Vocational Education for Handicapped Students in New York City High Schools" (F. Yauch); "Development of a Comprehensive Program for High School…

  20. Crataegus special extract WS(®)1442 prevents aging-related endothelial dysfunction.

    PubMed

    Idris-Khodja, N; Auger, C; Koch, E; Schini-Kerth, V B

    2012-06-15

    Aging is associated with a markedly increased incidence of cardiovascular diseases due, in part, to the development of vascular endothelial dysfunction. The present study has evaluated whether the Crataegus special extract WS(®)1442 prevents the development of aging-related endothelial dysfunction in rats, and, if so, to determine the underlying mechanisms. Wistar rats received either a control diet or the same diet containing 100 or 300 mg/kg/day of WS(®)1442 from week 25 until week 65. Vascular reactivity was assessed in mesenteric artery rings using organ chambers, oxidative stress by dihydroethidine staining and cyclooxygenase-1 (COX-1) and -2 (COX-2) expression by immunohistochemistry. Acetylcholine-induced endothelium-dependent relaxations in mesenteric artery rings were blunted in 65-week-old rats compared to 16-week-old rats. This effect was associated with a marked reduction of the endothelium-derived hyperpolarizing factor (EDHF) component whereas the nitric oxide (NO) component was not affected. Aging was also associated with the induction of endothelium-dependent contractile responses to acetylcholine. Both aging-related impairment of endothelium-dependent relaxations and the induction of endothelium-dependent contractile responses were improved by the Crataegus treatment and by COX inhibitors. An excessive vascular oxidative stress and an upregulation of COX-1 and COX-2 were observed in the mesenteric artery of old rats compared to young rats, and these effects were improved by the Crataegus treatment. In conclusion, chronic intake of Crataegus prevented aging-related endothelial dysfunction by reducing the prostanoid-mediated contractile responses, most likely by improving the increased oxidative stress and the overexpression of COX-1 and COX-2. Copyright © 2012 Elsevier GmbH. All rights reserved.

  1. The role of time and time perspective in age-related processes: Introduction to the special issue.

    PubMed

    Fung, Helene H; Isaacowitz, Derek M

    2016-09-01

    There currently appears to be a general consensus on the relationship between time perspective and aging, such that (a) future time is perceived as more limited with age and (b) older people are more present-focused and less future-focused than younger people. At the same time, there are debates about whether these age differences are positively related to well-being and to what extent there are boundary conditions beyond which these age differences would cease to occur. The 8 manuscripts included in this Special Issue attempt to shed light on these debates. In doing so, they refine the dominant theoretical perspective on the topic-socioemotional selectivity theory-and introduce new theoretical perspectives. New measures and methodologies for studying time perspective and aging are also discussed. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  2. [Aging in Mexico].

    PubMed

    Contreras de Lehr, E

    1986-01-01

    Demographic social and economic aspects of the situation of the elderly in Mexico are described with special emphasis upon education programmes and types of care in nursing homes. Considering the future trends of an increase in Mexico's elderly population, the author calls for more efforts in research and training in the field of gerontology. First results in this area are reported.

  3. Applying Continuous Quality Improvement Principles in Secondary School Vocational Education, with Emphasis on Special Populations.

    ERIC Educational Resources Information Center

    McLean, Gary N.

    1993-01-01

    Principles of quality management applicable to education for secondary special populations include process orientation, cascading, top commitment, vertical/horizontal communication, continuous improvement, shared vision, primacy of customers, investment in people, constancy of purpose, and shared goal setting. (JOW)

  4. Association of Bullying Behavior at 8 Years of Age and Use of Specialized Services for Psychiatric Disorders by 29 Years of Age.

    PubMed

    Sourander, Andre; Gyllenberg, David; Brunstein Klomek, Anat; Sillanmäki, Lauri; Ilola, Anna-Marja; Kumpulainen, Kirsti

    2016-02-01

    Bullying and being exposed to bullying among children is prevalent, especially among children with psychiatric symptoms, and constitutes a major concern worldwide. Whether childhood bullying or exposure to bullying in the absence of childhood psychiatric symptoms is associated with psychiatric outcomes in adulthood remains unclear. To study the associations between bullying behavior at 8 years of age and adult psychiatric outcomes by 29 years of age. Nationwide birth cohort study of 5034 Finnish children with complete information about childhood bullying behavior was followed up from 8 to 29 years of age. Follow-up was completed on December 31, 2009, and data were analyzed from January 15, 2013, to February 15, 2015. Information about bullying, exposure to bullying, and psychiatric symptoms were obtained from parents, teachers, and child self-reports when children were 8 years of age. Use of specialized services for psychiatric disorders from 16 to 29 years of age was obtained from a nationwide hospital register, including outpatient and inpatient treatment. Among the 5034 study participants, 4540 (90.2%) did not engage in bullying behavior; of these, 520 (11.5%) had received a psychiatric diagnosis at follow-up; 33 of 166 (19.9%) who engaged in frequent bullying, 58 of 251 (23.1%) frequently exposed to bullying, and 24 of 77 (31.2%) who both frequently engaged in and were frequently exposed to bullying had received psychiatric diagnoses at follow-up. When analyses were adjusted by sex, family factors, and child psychiatric symptoms at 8 years of age, we found independent associations of treatment of any psychiatric disorder with frequent exposure to bullying (hazard ratio [HR], 1.9; 95% CI, 1.4-2.5) and being a bully and exposed to bullying (HR, 2.1; 95% CI, 1.3-3.4). Exposure to bullying was specifically associated with depression (HR, 1.9; 95% CI, 1.2-2.9). Bullying was associated with psychiatric outcomes only in the presence of psychiatric problems at 8 years

  5. Applied Mathematics in EM Studies with Special Emphasis on an Uncertainty Quantification and 3-D Integral Equation Modelling

    NASA Astrophysics Data System (ADS)

    Pankratov, Oleg; Kuvshinov, Alexey

    2016-01-01

    second part, we summarize modern trends in the development of efficient 3-D EM forward modelling schemes with special emphasis on recent advances in the integral equation approach.

  6. Comparative Approaches to Understanding the Relation Between Aging and Physical Function

    PubMed Central

    Cesari, Matteo; Seals, Douglas R.; Shively, Carol A.; Carter, Christy S.

    2016-01-01

    Despite dedicated efforts to identify interventions to delay aging, most promising interventions yielding dramatic life-span extension in animal models of aging are often ineffective when translated to clinical trials. This may be due to differences in primary outcomes between species and difficulties in determining the optimal clinical trial paradigms for translation. Measures of physical function, including brief standardized testing batteries, are currently being proposed as biomarkers of aging in humans, are predictive of adverse health events, disability, and mortality, and are commonly used as functional outcomes for clinical trials. Motor outcomes are now being incorporated into preclinical testing, a positive step toward enhancing our ability to translate aging interventions to clinical trials. To further these efforts, we begin a discussion of physical function and disability assessment across species, with special emphasis on mice, rats, monkeys, and man. By understanding how physical function is assessed in humans, we can tailor measurements in animals to better model those outcomes to establish effective, standardized translational functional assessments with aging. PMID:25910845

  7. Preventive dental health care experiences of preschool-age children with special health care needs

    PubMed Central

    Huebner, Colleen E.; Chi, Donald L.; Masterson, Erin; Milgrom, Peter

    2014-01-01

    Purpose This study examined the preventive dental health care experiences of young children with special needs and determined the feasibility of conducting clinical dental examinations at a community-based early intervention services center. Methods Study methods included 90 parent interviews and dental examinations of their preschool-age children. Results Thirteen percent of the children received optimal preventive care, defined as twice daily tooth brushing with fluoridated toothpaste and two preventive dental visits in the prior 12 months; 37 percent experienced care that fell short in both areas. Optimal care was more common among children of parents who reported tooth brushing was not a struggle and those with a personal dentist. Parents' opinion of the study experience was generally positive. Conclusions Few children with special needs receive effective preventive care early, when primary prevention could be achieved. Barriers to optimal care could be readily addressed by the dental community in coordination with early intervention providers. PMID:25082666

  8. The "New" Competition: Serving the Learning Society in an Electronic Age.

    ERIC Educational Resources Information Center

    El-Khawas, Elaine

    1999-01-01

    Examines the changing environment for serving adult learners, with special attention to new modes of delivering instruction: distance education; use of information technology; emphasis on convenience; focus on special markets; and emergence of large-scale, profit-driven enterprises. Argues that, to develop an effective response, universities must…

  9. Modern Special Collections Cataloguing: A University of London Case Study

    ERIC Educational Resources Information Center

    Attar, K. E.

    2013-01-01

    Recent years have seen a growing emphasis on modern special collections (in themselves no new phenomenon), with a dichotomy between guidance for detailed cataloguing in "Descriptive Cataloging of Rare Materials (Books)" (DCRM(B), 2007) and the value of clearing cataloguing backlogs expeditiously. This article describes the De la Mare…

  10. Opinion on Recent Developments and the Future of Special Education

    ERIC Educational Resources Information Center

    Kauffman, James M.

    2015-01-01

    Three encouraging trends in special education are greater focus on instruction, emphasis on positive approaches to problem behavior, and greater reliance on scientific evidence. Next steps involving instruction should include research on modifications of instruction needed to accommodate learners with disabilities and on the place in which these…

  11. Numerical Hydrodynamics in Special Relativity.

    PubMed

    Martí, J M; Müller, E

    1999-01-01

    This review is concerned with a discussion of numerical methods for the solution of the equations of special relativistic hydrodynamics (SRHD). Particular emphasis is put on a comprehensive review of the application of high-resolution shock-capturing methods in SRHD. Results obtained with different numerical SRHD methods are compared, and two astrophysical applications of SRHD flows are discussed. An evaluation of the various numerical methods is given and future developments are analyzed. Supplementary material is available for this article at 10.12942/lrr-1999-3.

  12. 77 FR 39498 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-03

    ... announced below concerns Special Interest Project (SIP): Assessing the Pregnancy Prevention Needs of HIV... evaluation of applications received in response to ``Assessing the Pregnancy Prevention Needs of HIV...

  13. Planning and Implementing Career Education for the Special Student, with Emphasis on the Leisure Occupations.

    ERIC Educational Resources Information Center

    Vinton, Dennis A.; And Others

    A program of career education for exceptional students in the leisure occupations is described. It is explained that the book is designed for regular and special class teachers. Chapters one and two present information on career education principles and implementation. Chapters three through five deal with practical teaching concerns. Behavioral…

  14. Special diets are common among preschool children aged one to five years in south-east Sweden according to a population-based cross-sectional survey.

    PubMed

    Servin, Caroline; Hellerfelt, Sofia; Botvid, Christina; Ekström, Magnus

    2017-04-01

    Information about the prevalence of special diets in preschool children is limited. The aim of this study was to measure the prevalence of all special diets among preschool children in a Swedish municipality. This was a population-based cross-sectional survey of all 3276 preschool children aged one to five years in the municipality of Karlskrona, Sweden. The questionnaire assessed the number of children at each preschool, how many were on special diets, their dietary requirements, age, sex, whether they had a medical certificate and whether the special diet had a perceived medical cause. We obtained data for 3221 (98%) of the children, and 19% had special diets, including 12% on nonmedical diets and 6.3% on medical diets. The five most common diets were avoiding pork (7.8%), a vegetarian diet (4.8%), and avoiding cows' milk (3.5%), hens' eggs (1.2%) and lactose (1.1%). Gluten avoidance was more common in girls than boys (0.8% versus 0.2%, p = 0.032). Half (47%) of the children on special medical diets lacked a medical certificate. Special diets were common in preschool children in south-east Sweden, and the causes were mainly nonmedical. Mandatory medical certificates for medically based special diets might reduce unnecessary dietary restrictions. ©2017 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

  15. 14 CFR Special Federal Aviation... - Process for Requesting Waiver of Mandatory Separation Age for a Federal Aviation Administration...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Process for Requesting Waiver of Mandatory Separation Age for a Federal Aviation Administration Air Traffic Control Specialist In Flight Service..., SFAR 103 Special Federal Aviation Regulation No. 103—Process for Requesting Waiver of Mandatory...

  16. 28 CFR 42.714 - Special benefits.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Special benefits. 42.714 Section 42.714 Judicial Administration DEPARTMENT OF JUSTICE NONDISCRIMINATION; EQUAL EMPLOYMENT OPPORTUNITY; POLICIES AND... of the Age Discrimination Act of 1975 Standards for Determining Age Discrimination § 42.714 Special...

  17. On the Special Problems in Creating Group Cohesion Within the Prison Setting.

    ERIC Educational Resources Information Center

    Juda, Daniel P.

    1983-01-01

    Describes attempts to form a communication group among male and female inmates. The failure of this effort is discussed with emphasis on the special problems and needs of groups in prisons and the lack of insight among the institution's administration and staff. (JAC)

  18. 78 FR 19490 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-01

    ... announced below concerns Attitudes Towards Cognitive Health, Cognitive Impairment, and Caregiving--Identifying Attitude Questions and Measures for Public Health Practice, Special Interest Project (SIP)13-071... review, discussion, and evaluation of ``Attitudes Towards Cognitive Health, Cognitive Impairment, and...

  19. The Essential Special Education Guide for the Regular Education Teacher

    ERIC Educational Resources Information Center

    Burns, Edward

    2007-01-01

    The Individuals with Disabilities Education Act (IDEA) of 2004 has placed a renewed emphasis on the importance of the regular classroom, the regular classroom teacher and the general curriculum as the primary focus of special education. This book contains over 100 topics that deal with real issues and concerns regarding the regular classroom and…

  20. Achieving Inclusion? Effective Resourcing of Students with Special Educational Needs

    ERIC Educational Resources Information Center

    Banks, Joanne; Frawley, Denise; McCoy, Selina

    2015-01-01

    In line with the increasing policy emphasis on inclusive education, there is now a greater focus on how best to provide for students special educational needs (SEN) in mainstream schools. However, there is little consensus internationally as to the most equitable way in which to support these students. Despite ongoing evaluations of the existing…

  1. Factors That Drive Youth Specialization.

    PubMed

    Padaki, Ajay S; Popkin, Charles A; Hodgins, Justin L; Kovacevic, David; Lynch, Thomas Sean; Ahmad, Christopher S

    Specialization in young athletes has been linked to overuse injuries, burnout, and decreased satisfaction. Despite continued opposition from the medical community, epidemiological studies suggest the frequency is increasing. Extrinsic pressures in addition to individual aspirations drive this national trend in sports specialization. Descriptive epidemiology study. Level 3. A novel instrument assessing the driving factors behind youth specialization was generated by an interdisciplinary team of medical professionals. Surveys were administered to patients and athletes in the department's sports medicine clinic. The survey was completed by 235 athletes between 7 and 18 years of age, with a mean age of 13.8 ± 3.0 years. Athletes specialized at a mean age of 8.1 years, and 31% of athletes played a single sport while 58% played multiple sports but had a preferred sport. More than 70% of athletes had collegiate or professional ambitions, and 60% played their primary sport for 9 or more months per year, with players who had an injury history more likely to play year-round ( P < 0.01). Approximately one-third of players reported being told by a coach not to participate in other sports, with specialized athletes reporting this significantly more often ( P = 0.04). Half of the athletes reported that sports interfered with their academic performance, with older players stating this more frequently ( P < 0.01). Young athletes are increasingly specializing in a single sport before starting high school. While intrinsic drive may identify healthy aspirations, extrinsic influences are prevalent in specialized athletes. Extrinsic factors contributing to youth specialization were identified and compounded the deleterious sequelae of youth athlete specialization.

  2. 77 FR 39497 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-03

    ... announced below concerns Special Interest Projects (SIPs): Nutrition and Obesity Policy Research and Evaluation Network (NOPREN)--Coordinating Center, SIP12-061 and Nutrition and Obesity Policy Research and... received in response to ``Nutrition and Obesity Policy Research and Evaluation Network (NOPREN...

  3. 78 FR 19490 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-01

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease... announced below concerns Development of an Evidenced-- Informed Mall Walking Program Resource Guide, Special... review, discussion, and evaluation of ``Development of an Evidenced--Informed Mall Walking Program...

  4. 77 FR 39497 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-03

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease... announced below concerns Special Interest Project (SIP): Evaluation of School Salad Bars as a Public Health...), the Centers for Disease Control and Prevention (CDC) announces the aforementioned meeting: Time and...

  5. Virtual environments special needs and evaluative methods.

    PubMed

    Brown, D J; Standen, P J; Cobb, S V

    1998-01-01

    This paper presents an overview of the development of the Learning in Virtual Environments programme (LIVE), carried out in special education over the last four years. It is more precisely a project chronology, so that the reader can sense the historical development of the programme rather than giving emphasis to any one particular feature or breakthrough, which are covered in other papers and available through the authors. The project conception in a special school in Nottingham is followed by a description of the development of experiential and communicational virtual learning environments. These are followed, in turn, by the results of our testing programmes which show that experience gained in a virtual environment can transfer to the real world and that their use can encourage self-directed activity in students with severe learning difficulties. Also included is a discussion of the role of virtual learning environments (VLEs) in special education and of its attributes in the context of contemporary educational theory.

  6. Comparative Approaches to Understanding the Relation Between Aging and Physical Function.

    PubMed

    Justice, Jamie N; Cesari, Matteo; Seals, Douglas R; Shively, Carol A; Carter, Christy S

    2016-10-01

    Despite dedicated efforts to identify interventions to delay aging, most promising interventions yielding dramatic life-span extension in animal models of aging are often ineffective when translated to clinical trials. This may be due to differences in primary outcomes between species and difficulties in determining the optimal clinical trial paradigms for translation. Measures of physical function, including brief standardized testing batteries, are currently being proposed as biomarkers of aging in humans, are predictive of adverse health events, disability, and mortality, and are commonly used as functional outcomes for clinical trials. Motor outcomes are now being incorporated into preclinical testing, a positive step toward enhancing our ability to translate aging interventions to clinical trials. To further these efforts, we begin a discussion of physical function and disability assessment across species, with special emphasis on mice, rats, monkeys, and man. By understanding how physical function is assessed in humans, we can tailor measurements in animals to better model those outcomes to establish effective, standardized translational functional assessments with aging. © The Author 2015. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  7. The Bureau of Indian Affairs is Slow in Providing Special Education Services to All Handicapped Indian Children.

    ERIC Educational Resources Information Center

    Comptroller General of the U.S., Washington, DC.

    Many handicapped Indian children in Bureau of Indian Affairs (BIA) schools are not receiving the benefits of special education services due to problems caused by poor leadership and a lack of emphasis on the program. Because of the late and incomplete evaluation of students, too few special education teachers have been hired, and funds that should…

  8. Special Session 4: Astronomy Education between Past and Future

    NASA Astrophysics Data System (ADS)

    de Greve, Jean-Pierre

    2010-11-01

    The special session aims at discussing an integrated approach of the different efforts to increase and promote the teaching and learning of astronomy in the world, with emphasis on developing countries. To this end, attention will be given to research on education, specifically in the field of physics, to best practices of the use of astronomy in educational systems (specifically in developing countries), and to innovative learning initiatives other than formal education. The Special Session aims also at creating a universal perspective wherein modern (post-Copernican) astronomy will presented as an intellectual cumulus. The objective of the session is to disseminate best practices in teaching and learning activities of astronomy and to give an opportunity to learn about initiatives in different cultural and socio-economic settings. The special session also wants to give food-for-thought and proposals for reflection for an integrative approach, and for optimization processes, to enhance the interest in astronomy and its role as a trigger towards science education in the educational systems, with emphasis on the developing countries. The outcome should be a sensitization of teachers and students alike to the concept of a universal history of astronomy and creation of some reliable source material which can be used as a teaching aid in a culture-specific context. The outcome could be a set of recommendations for future integrated actions, and eventually recommendations on new initiatives, framed into the new decadal policy plan.

  9. 78 FR 19489 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-01

    ..., Special Interest Project (SIP)13-067; and Feasibility Study of the New Clinical Measure of Colorectal... Determination of the Director, Management Analysis and Services Office, CDC, pursuant to Public Law 92-463... ``Understanding the Barriers to Colorectal Cancer Screening among Asian Subgroups, SIP13-067; and Feasibility...

  10. Sport Specialization, Part I

    PubMed Central

    Myer, Gregory D.; Jayanthi, Neeru; Difiori, John P.; Faigenbaum, Avery D.; Kiefer, Adam W.; Logerstedt, David; Micheli, Lyle J.

    2015-01-01

    Context: There is increased growth in sports participation across the globe. Sports specialization patterns, which include year-round training, participation on multiple teams of the same sport, and focused participation in a single sport at a young age, are at high levels. The need for this type of early specialized training in young athletes is currently under debate. Evidence Acquisition: Nonsystematic review. Study Design: Clinical review. Level of Evidence: Level 4. Conclusion: Sports specialization is defined as year-round training (greater than 8 months per year), choosing a single main sport, and/or quitting all other sports to focus on 1 sport. Specialized training in young athletes has risks of injury and burnout, while the degree of specialization is positively correlated with increased serious overuse injury risk. Risk factors for injury in young athletes who specialize in a single sport include year-round single-sport training, participation in more competition, decreased age-appropriate play, and involvement in individual sports that require the early development of technical skills. Adults involved in instruction of youth sports may also put young athletes at risk for injury by encouraging increased intensity in organized practices and competition rather than self-directed unstructured free play. Strength-of-Recommendation Taxonomy (SORT): C. PMID:26502420

  11. Public Services and Outreach in Rare Book, Manuscript, and Special Collections Libraries.

    ERIC Educational Resources Information Center

    Traister, Daniel

    2003-01-01

    Discusses the new emphasis in special collections, especially in academic libraries, on the promotion of materials. Highlights include the economic basis of promotion; exhibitions; classroom ventures; the Web; seminars and other discussion groups; creative writing courses; one-time events; friends, tourists, and the public; and reference services.…

  12. Lunar Get Away Special (GAS) spacecraft

    NASA Technical Reports Server (NTRS)

    Nock, K. T.; Aston, G.; Salazar, R. P.; Stella, P. M.

    1987-01-01

    A new approach to the resumption of Lunar missions is discussed which relies upon Shuttle Get-Away-Special Canisters for launch and solar electric ion propulsion for slow orbit transfer to low Lunar orbit. The technique of orbit transfer is outlined along with a summary of a mission profile for a first mission which could carry a Gamma Ray Spectrometer. System design constraints are discussed followed by a description of the low mass spacecraft concept which has been developed. Particular emphasis is placed upon describing the small solar electric, xenon ion propulsion system.

  13. [Trends among medical students towards general practice or specialization].

    PubMed

    Breinbauer K, Hayo; Fromm R, Germán; Fleck L, Daniela; Araya C, Luis

    2009-07-01

    A 60/40 ratio has been estimated as a country's ideal proportion between general practitioners and specialists. In Chile this proportion was 36/ 64 in 2004, exactly the opposite of the ideal. Trends towards specialization or general practice among medical students have not been thoughtfully studied. To assess trends among medical students towards becoming general practitioners or specialists, exploring associated factors. Descriptive survey of 822 first to seventh year medical students at the University of Chile, School of Medicine. Desired activity to pursue (general practice or specialization) after graduation and general orientations within clinical practice were explored. Fifty three percent of students desired to enter a specialization program. Only 20% would work as a general practitioner (27% were still indecisive). Furthermore, a trend in early years of medical training towards an integral medicine is gradually reversed within later years. Seventh year students give significantly more importance to specialization than to integral medicine (p <0.01). Ten percent of this opinion change is related to the emphasis given to specialized medicine in the teaching environment. Most students prefer to enter a specialization program immediately after finishing medical school. Moreover, there is a social trend, at least within the teacher-attending environment, promoting not only the desire to specialize, but a pro-specialist culture.

  14. Factors Related to Special Education Teacher Job Commitment: A Study of One Large Metropolitan School District in Southern California

    ERIC Educational Resources Information Center

    Green, Joseph David

    2011-01-01

    Researchers have focused their attention on the subject of special education teacher attrition for many years. While these researchers have made valuable findings, the need to abate the staggering numbers of special education teachers who leave the field still exists. Districts desiring to retain their teachers must place greater emphasis on the…

  15. Special Education Policy: A Retrospective and Future Prospective--A View from Saskatchewan.

    ERIC Educational Resources Information Center

    Dahl, Harry; Sanche, Robert

    This paper reviews the history of special education in Saskatchewan (Canada) since the 1960s and proposes policy initiatives for future changes. Emphasis in the discussion is on trends and Canadian reports that led to Saskatchewan's 1971 passing of legislation mandating an "appropriate" free public education with procedural due process,…

  16. Somatostatin-immunoreactive senile plaque-like structures in the frontal cortex and nucleus accumbens of aged tree shrews and Japanese macaques.

    PubMed

    Yamashita, Akiko; Fuchs, Eberhard; Taira, Masato; Yamamoto, Takamitsu; Hayashi, Motoharu

    2012-06-01

    Previously, we demonstrated decreased expression of somatostatin mRNA in aged macaque brain, particularly in the prefrontal cortex. To investigate whether or not this age-dependent decrease in mRNA is related to morphological changes, we analyzed somatostatin cells in the cerebra of aged Japanese macaques and compared them with those in rats and tree shrews, the latter of which are closely related to primates. Brains of aged macaques, tree shrews, and rats were investigated by immunohistochemistry with special emphasis on somatostatin. We observed degenerating somatostatin-immunoreactive cells in the cortices of aged macaques and tree shrews. Somatostatin-immunoreactive senile plaque-like structures were found in areas 6 and 8 and in the nucleus accumbens of macaques, as well as in the nucleus accumbens and the cortex of aged tree shrews, where amyloid accumulations were observed. Somatostatin degenerations may be related to amyloid accumulations and may play roles in impairments of cognitive functions during aging. © 2012 John Wiley & Sons A/S.

  17. Clinical and Radiological Long-Term Outcome of a Tapered Implant System with Special Emphasis on the Influence of Augmentation Procedures.

    PubMed

    Schiegnitz, Eik; Al-Nawas, Bilal; Tegner, Alexander; Sagheb, Keyvan; Berres, Manfred; Kämmerer, Peer W; Wagner, Wilfried

    2016-08-01

    Tapered implant designs aim to improve primary stability and implant survival in soft bone. However, respective clinical long-term data are scarce. Therefore, a clinical and radiological evaluation of the long-term success of a transgingival-supracrestal inserted tapered implant system with special emphasis on the influence of augmentation procedures was conducted. In a retrospective study design, all in the Department of Oral and Maxillofacial Surgery of the University Medical Centre, Mainz, Germany, between May 2002 and March 2012, placed tapered implants (Straumann TE®, Basel, Switzerland) were analyzed. In this time period, a total of one hundred ninety-seven tapered implants were inserted in 90 patients. For patients available for clinical recall, success criteria according to Albrektsson and Buser were evaluated. The in situ rate was 96.3% after an average time in situ of 62 ± 31 months. In one hundred twenty-seven sites, bone augmentation procedures were performed. Hereof, 96 sites were sinus augmentation procedures and 31 sites were alveolar ridge augmentations. For patients with sinus augmentation procedures, implant survival was 97.9% and for patients with alveolar ridge augmentations, implant survival was 93.5% after 5 years, indicating a higher implant survival for sinus augmentation, however not statistically different (p = .194). Implant diameter and timing of implant placement had no significant impact on implant survival (p > .05). Mean marginal bone loss was -0.50 ± 1.54 mm for patients receiving maxillary sinus augmentation and -1.16 ± 1.13 mm for patients with alveolar ridge augmentations, indicating a lower marginal bone loss in patients receiving maxillary sinus augmentation (p = .046). Implant success rates ranged between 88% and 92% after a mean follow-up of 6 years. Within the limits of the retrospective character of this study, the tapered soft tissue level implant showed especially in maxillary sinus

  18. Five years of interdisciplinary research on ageing and technology: Outcomes of the Lower Saxony Research Network Design of Environments for Ageing (GAL)--an introduction to this Special Issue on Ageing and Technology.

    PubMed

    Haux, Reinhold; Hein, Andreas; Kolb, Gerald; Künemund, Harald; Eichelberg, Marco

    2014-01-01

    This Special Issue of Informatics for Health and Social Care is presenting outcomes of the Lower Saxony Research Network Design of Environments for Ageing (abbreviated as GAL), probably one of the largest inter- and multidisciplinary research projects on aging and technology. In order to investigate and provide answers on whether new information and communication technologies can contribute to keeping, or even improving quality of life, health and self-sufficiency in ageing societies through new ways of living and new forms of care, GAL had been established as a five-year research project, running from 2008 to 2013. Ambient-assisted living technologies in personal and home environments were especially important. During the five years of research in GAL, more than seventy researchers from computer science, economics, engineering, geriatrics, gerontology, informatics, medicine, nursing science and rehabilitation pedagogy intensively collaborated in finding answers.

  19. The environment of ageing.

    PubMed Central

    Tinker, A

    1997-01-01

    The issue of housing and the wider environment for an ageing population is one where there are many unanswered questions. In this paper a number of key issues are discussed and for each of these the focus is on three aspects. These are the current situation, its reasonableness and what research is needed in order to make decisions about policy and practice. The first three issues relate to the profile of older people themselves and the importance of home to them. The changing profile of older people is not just about an ageing population but also about the growing prominence of those with dementia, women, people from black and ethnic minority groups and one person households, yet little is known about the type of housing which should be provided. Of equal concern is the widening gap between those with a high standard of living (including housing) and those with a low standard of living. The importance of home to older people means that research must focus on how people can be enabled to remain there, and also on the costs, financial and otherwise, to carers and to society. The next three issues relate to the type of housing older people live in and moves in later life. The startling change in the tenure pattern with a growth of owner occupation brings problems as does the decline in social housing. The advantages and disadvantages of the different types of housing--mainstream and specialized--for older people are relatively well known. However the balance between the two needs more research as does that on retirement communities. While it is well known that there are peaks of migration in old age and that moves are often made in haste, little is known about the process of decision making. The final two topics concern links between housing and other aspects of older people's lives. On health more research is needed on temperature, mortality and morbidity, homelessness and accidents and especially on links between services. These topics have implications for planning

  20. Aeronautical Engineering: A special bibliography with indexes, supplement 13

    NASA Technical Reports Server (NTRS)

    1972-01-01

    This special bibliography lists 283 reports, articles, and other documents introduced into the NASA scientific and technical information system in December, 1971. Emphasis is placed on engineering and theoretical aspects for design, construction, evaluation, testing, operation and performance of aircraft (including aircraft engines), and associated components, equipment and systems. Also included are entries on research and development in aeronautics and aerodynamics and research and ground support for aeronautical vehicles.

  1. Aeronautical Engineering, a special bibliography with indexes, supplement 15

    NASA Technical Reports Server (NTRS)

    1972-01-01

    This special bibliography lists 363 reports, articles, and other documents introduced into the NASA scientific and technical information system in January 1972. Emphasis is placed on engineering and theoretical aspects for design, construction, evaluation, testing, operation and performance of aircraft (including aircraft engines) and associated components, equipment and systems. Also included are entries on research and development in aeronautics and aerodynamics and research and ground support for aeronautical vehicles.

  2. The zebrafish as a gerontology model in nervous system aging, disease, and repair.

    PubMed

    Van Houcke, Jessie; De Groef, Lies; Dekeyster, Eline; Moons, Lieve

    2015-11-01

    Considering the increasing number of elderly in the world's population today, developing effective treatments for age-related pathologies is one of the biggest challenges in modern medical research. Age-related neurodegeneration, in particular, significantly impacts important sensory, motor, and cognitive functions, seriously constraining life quality of many patients. Although our understanding of the causal mechanisms of aging has greatly improved in recent years, animal model systems still have much to tell us about this complex process. Zebrafish (Danio rerio) have gained enormous popularity for this research topic over the past decade, since their life span is relatively short but, like humans, they are still subject to gradual aging. In addition, the extensive characterization of its well-conserved molecular and cellular physiology makes the zebrafish an excellent model to unravel the underlying mechanisms of aging, disease, and repair. This review provides a comprehensive overview of the progress made in zebrafish gerontology, with special emphasis on nervous system aging. We review the evidence that classic hallmarks of aging can also be recognized within this small vertebrate, both at the molecular and cellular level. Moreover, we illustrate the high level of similarity with age-associated human pathologies through a survey of the functional deficits that arise as zebrafish age. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. Attitudes of Korean Dental Students Toward Individuals with Special Health Care Needs.

    PubMed

    Lee, Hyo-Seol; Jung, Hoi In; Kim, Seon-Mi; Kim, Jiyoen; Doh, Re Mee; Lee, Jae-Ho

    2015-09-01

    The purposes of this study were to ascertain the attitudes of dental students toward individuals with special health care needs (SHCNs) in Korea and to elucidate the characteristics associated with these attitudes. The authors recruited students from four of the 11 dental schools in Korea to participate in a survey; these schools were selected for regional balance. The Scale of Attitudes toward Disabled Persons (SADP) was used as the primary survey instrument, and ten independent variables were included. Of the 1,100 possible participants, 1,057 responded to the survey, for a response rate of 96.1%. The results showed that although the students' attitudes did not differ significantly by gender, their attitudes did show statistically significant differences on nine other variables: age, year, religion, self-esteem, friends with a disability, volunteering, admission course, concern for individuals with SHCNs, and intention to treat individuals with SHCNs (all p<0.05). The attitudes of these Korean dental students toward individuals with SHCNs were relatively unfavorable, showing lower SADP scores than reported in Western countries and likely reflecting Eastern cultural values in general. Future efforts should place greater emphasis on special care dentistry education and encourage the development of more favorable attitudes regarding the treatment of individuals with SHCNs.

  4. Special Reports.

    ERIC Educational Resources Information Center

    Haycock, Ken; Chapin, Betty; Bruce, David; Durrance, Joan C.; Pettigrew, Karen; Oakley, Robert L.; Juergens, Bonnie; Nevins, Kate

    1999-01-01

    Presents these special reports: "Information Age Dilemma: Filtering the Internet for Young People"; "KALIPER: A Look at Library and Information Science Education at the Turn of a New Century"; "Copyright 1998: Recalibrating the Balance"; "Library Networking and Cooperation in 1998". (AEF)

  5. Linking Medical Education and Training to Rural America: Obstacles and Opportunities. Workshop before the Special Committee on Aging. United States Senate, One Hundred Second Congress, First Session (July 29, 1991).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    This document represents proceedings of a workshop before the Senate Special Committee on Aging. The workshop focused on the severe shortage of health professionals in the rural health care system. Opening remarks by Portia Mittelman, Staff Director of the Special Committee on Aging and Jeffrey Human, Director of the Office of Rural Health Policy…

  6. Impact of maternal age on obstetric and neonatal outcome with emphasis on primiparous adolescents and older women: a Swedish Medical Birth Register Study.

    PubMed

    Blomberg, Marie; Birch Tyrberg, Rasmus; Kjølhede, Preben

    2014-11-11

    To evaluate the associations between maternal age and obstetric and neonatal outcomes in primiparous women with emphasis on teenagers and older women. A population-based cohort study. The Swedish Medical Birth Register. Primiparous women with singleton births from 1992 through 2010 (N=798,674) were divided into seven age groups: <17 years, 17-19 years and an additional five 5-year classes. The reference group consisted of the women aged 25-29 years. Obstetric and neonatal outcome. The teenager groups had significantly more vaginal births (adjusted OR (aOR) 2.04 (1.79 to 2.32) and 1.95 (1.88 to 2.02) for age <17 years and 17-19 years, respectively); fewer caesarean sections (aOR 0.57 (0.48 to 0.67) and 0.55 (0.53 to 0.58)), and instrumental vaginal births (aOR 0.43 (0.36 to 0.52) and 0.50 (0.48 to 0.53)) compared with the reference group. The opposite was found among older women reaching a fourfold increased OR for caesarean section. The teenagers showed no increased risk of adverse neonatal outcome but presented an increased risk of prematurity <32 weeks (aOR 1.66 (1.10 to 2.51) and 1.20 (1.04 to 1.38)). Women with advancing age (≥30 years) revealed significantly increased risk of prematurity, perineal lacerations, preeclampsia, abruption, placenta previa, postpartum haemorrhage and unfavourable neonatal outcomes compared with the reference group. For clinicians counselling young women it is of importance to highlight the obstetrically positive consequences that fewer maternal complications and favourable neonatal outcomes are expected. The results imply that there is a need for individualising antenatal surveillance programmes and obstetric care based on age grouping in order to attempt to improve the outcomes in the age groups with less favourable obstetric and neonatal outcomes. Such changes in surveillance programmes and obstetric interventions need to be evaluated in further studies. Published by the BMJ Publishing Group Limited. For permission to use (where

  7. Emphasis: Teachers Doing Research.

    ERIC Educational Resources Information Center

    Knudson, Richard L., Ed.

    1975-01-01

    The emphasis of this issue, reflecting increased demand for accountability, is the importance of teachers gathering data which substantiate pupil growth and present facts about what is going on in English classrooms, especially when teachers are trying different classroom approaches. Articles also discuss student responses to literature, student…

  8. Special Education Solutions in the Age of NCLB

    ERIC Educational Resources Information Center

    Harvey, Cathryn

    2004-01-01

    The No Child Left Behind Act specifies schools' responsibilities for including special education students in their overall assessment programs. These students must be assessed under a standardized test that is used for all students within a district--a test that is designed to show whether a student is meeting that state's standards for learning.…

  9. Neuroanatomical dichotomy of sexual behaviors in rodents: a special emphasis on brain serotonin.

    PubMed

    Angoa-Pérez, Mariana; Kuhn, Donald M

    2015-09-01

    and male sexual behavior and the participation of the serotonin system in the modulation of these behaviors, with emphasis on rodents.

  10. Neuroanatomical dichotomy of sexual behaviors in rodents: a special emphasis on brain serotonin

    PubMed Central

    Angoa-Pérez, Mariana; Kuhn, Donald M.

    2016-01-01

    sexual behavior and the participation of the serotonin system in the modulation of these behaviors with emphasis on rodents. PMID:26110223

  11. An Educational Response to Aging.

    ERIC Educational Resources Information Center

    McLain, Rosemary

    1978-01-01

    The emphasis of this article is on aging and the needs of the elderly as a basis for developing educational content in the curriculum. It includes a description of a theoretical framework developed by Abraham Maslow for a holistic approach to needs of the aged. (Editor/RK)

  12. Emphasizing the only character: emphasis, attention and contrast.

    PubMed

    Chen, Lijing; Yang, Yufang

    2015-03-01

    In conversations, pragmatic information such as emphasis is important for identifying the speaker's/writer's intention. The present research examines the cognitive processes involved in emphasis processing. Participants read short discourses that introduced one or two character(s), with the character being emphasized or non-emphasized in subsequent texts. Eye movements showed that: (1) early processing of the emphasized word was facilitated, which may have been due to increased attention allocation, whereas (2) late integration of the emphasized character was inhibited when the discourse involved only this character. These results indicate that it is necessary to include other characters as contrastive characters to facilitate the integration of an emphasized character, and support the existence of a relationship between Emphasis and Contrast computation. Taken together, our findings indicate that both attention allocation and contrast computation are involved in emphasis processing, and support the incremental nature of sentence processing and the importance of contrast in discourse comprehension. Copyright © 2014 Elsevier B.V. All rights reserved.

  13. Postmortem Aging of Beef with a Special Reference to the Dry Aging

    PubMed Central

    Khan, Muhammad I.; Jung, Samooel; Nam, Ki Chang; Jo, Cheorun

    2016-01-01

    Animal muscles are stored for specific period (aging) at refrigerated temperatures, during and after which the living muscles start to convert into meat and thus, attain certain superior properties in the final product. Proteolysis, lipolysis, and oxidation are the major biochemical processes involved during the postmortem aging of meat that affect the tenderness, juiciness, and flavor, as well as sometimes may introduce certain undesirable traits. This review analyzes the role of pre- and post-mortem factors that are important for aging and their effect on the chemical and physical changes in the “dry- and wet-aged meat.” Thus, if the meat processing manufacturers optimize the effects of aging for specific muscles, the palatability, color, and the shelf life of the aged meat products could be significantly enhanced. PMID:27194923

  14. Bilingual and Special Educational Needs in Inclusive Classrooms: Some Critical and Pedagogical Considerations

    ERIC Educational Resources Information Center

    Liasidou, Anastasia

    2013-01-01

    In the light of educational reforms aimed at promoting greater inclusive policies and practices, it is important to put a more pronounced emphasis on the needs of English language learners (ELLs) with special educational needs and/or disabilities. Simultaneously, a focus should also be placed on understanding and dealing with the disproportional…

  15. A clinical study on oral lichen planus with special emphasis on hyperpigmentation

    PubMed Central

    Chitturi, Ravi Teja; Sindhuja, Pandian; Parameswar, R. Arjun; Nirmal, Ramdas Madhavan; Reddy, B. Venkat Ramana; Dineshshankar, Janardhanam; Yoithapprabhunath, Thukanayakanpalayam Ragunathan

    2015-01-01

    Background: Oral lichen planus (OLP) is a unique disorder affecting generally the older age group. Numerous studies have been done on various aspects of OLP such as pathogenesis, rate of malignant transformation, etc. However, very few studies are available with respect to clinical features especially association of hyperpigmentation and OLP. This study aims at studying the clinical aspects of OLP and study the association between hyperpigmentation and OLP in a south Indian population. Materials and Methods: A total of 58 patients with OLP who attended the outpatient department of our institution were included in the study and a complete history, followed by thorough intraoral examination was done. All the data were recorded and assessed for statistical analysis using SPSS software. Results: We found that the male to female ratio affected with OLP was 1:1 and the most common form of OLP that was seen was the reticular subtype. Also, buccal mucosa was the most common affected site and more than 60% patients had hyperpigmentation associated with the site affected by OLP. We found a statistically significant relation between the reticular type of OLP and the older age group (51–70 years) with hyperpigmentation. Conclusion: Although further studies are required to say anything conclusively, post-inflammatory changes occurring the mucosa due to OLP could be a cause for hyperpigmentation in the sites affected. PMID:26538905

  16. The Phenomenology of Specialization of Criminal Suspects

    PubMed Central

    Tumminello, Michele; Edling, Christofer; Liljeros, Fredrik; Mantegna, Rosario N.; Sarnecki, Jerzy

    2013-01-01

    A criminal career can be either general, with the criminal committing different types of crimes, or specialized, with the criminal committing a specific type of crime. A central problem in the study of crime specialization is to determine, from the perspective of the criminal, which crimes should be considered similar and which crimes should be considered distinct. We study a large set of Swedish suspects to empirically investigate generalist and specialist behavior in crime. We show that there is a large group of suspects who can be described as generalists. At the same time, we observe a non-trivial pattern of specialization across age and gender of suspects. Women are less prone to commit crimes of certain types, and, for instance, are more prone to specialize in crimes related to fraud. We also find evidence of temporal specialization of suspects. Older persons are more specialized than younger ones, and some crime types are preferentially committed by suspects of different ages. PMID:23691257

  17. Computational Age Dating of Special Nuclear Materials

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    2012-06-30

    This slide-show presented an overview of the Constrained Progressive Reversal (CPR) method for computing decays, age dating, and spoof detecting. The CPR method is: Capable of temporal profiling a SNM sample; Precise (compared with known decay code, such a ORIGEN); Easy (for computer implementation and analysis). We have illustrated with real SNM data using CPR for age dating and spoof detection. If SNM is pure, may use CPR to derive its age. If SNM is mixed, CPR will indicate that it is mixed or spoofed.

  18. A Life-Course Analysis of Offense Specialization across Age: Introducing a New Method for Studying Individual Specialization over the Life Course

    ERIC Educational Resources Information Center

    Nieuwbeerta, Paul; Blokland, Arjan A. J.; Piquero, Alex R.; Sweeten, Gary

    2011-01-01

    Much of the knowledge base on offense specialization indicates that, although there is some (short-term) specialization, it exists amidst much versatility in offending. Yet this general conclusion is drawn on studies using very different conceptualizations of specialization and emerges with data primarily through the first two to three decades of…

  19. Are Special Education Students Happy?

    ERIC Educational Resources Information Center

    Uusitalo-Malmivaara, Lotta; Kankaanpaa, Paula; Makinen, Tuula; Raeluoto, Tiina; Rauttu, Karoliina; Tarhala, Veera; Lehto, Juhani E.

    2012-01-01

    This study compared the subjective and school-related happiness of 75 11- to 16-year-old special education students to 77 age- and gender-matched mainstream students using two quantitative measures. Additionally, the respondents chose from a list of 12 putative happy makers what they felt increased their happiness. Ten special education students…

  20. Pre-Service, Professional Development, and Collaborative Practices Regarding Paraprofessionals, Special Education Teachers, and Administrators

    ERIC Educational Resources Information Center

    Beddow-Beste, Jolaine

    2012-01-01

    Administrators, teachers, and paraprofessionals play an important role in successful outcomes for students with special needs. Post-secondary training does not guarantee that emphasis is put on how each professional entity maintains the ability to collaborate with one another, and how to determine what continued training is pertinent for each of…

  1. Women Who Work, Part 2: Married Women in the Labour Force: The Influence of Age, Education, Child-Bearing Status and Residence. Special Labour Force Studies Series B, No. 2.

    ERIC Educational Resources Information Center

    Allingham, John D.; Spencer, Byron G.

    To followup an earlier study of the relative importance of age, education, and marital status as variables influencing female participation in the labor force, this research attempts to measure the relative importance of similar factors in determining whether or not a woman works or wishes to work. Particular emphasis was given to such…

  2. Lifelong Teacher Education in the Czechoslovakian Socialist Republic with Especial Reference to the Training of Teachers in Special Education.

    ERIC Educational Resources Information Center

    Cerna, Marie

    1987-01-01

    The structure of the Czechoslovak system of preservice and inservice teacher education introduced by Education Act No. 29 of 1984 is described. The preparation of special education teachers is given particular emphasis. (Author/MT)

  3. Understanding of Special Educational Needs Terms by Student Teachers and Student Paediatric Nurses

    ERIC Educational Resources Information Center

    Mintz, Joseph

    2010-01-01

    There has been a growing emphasis in recent years on inter-agency working in respect of the care and development of children. This is of particular relevance when considering the needs of children with special educational needs (SEN). Teachers and healthcare professionals are two groups who need to have a clear understanding of the meaning and…

  4. Improving Special Education in the Boston Public Schools: Report of the Strategic Support Team of the Council of the Great City Schools, Spring 2009

    ERIC Educational Resources Information Center

    Council of the Great City Schools, 2009

    2009-01-01

    This report presents the Council of the Great City Schools' findings and recommendations for improving the general education intervention and special education services of the Boston Public Schools. The report places special emphasis how the instructional program serves students with disabilities districtwide. The process that the Council used to…

  5. Special Education and the New Mental Health: A Response to New Direction of CCBD?

    ERIC Educational Resources Information Center

    Forness, Steven R.

    2011-01-01

    The emphasis or focus of a professional association often shifts imperceptibly over time in ways that neither its membership nor its leadership seems able to recognize until pivotal events compel it to do so. The historical shift from psychodynamic to behavioral approaches in special education for children with emotional or behavioral disorders…

  6. Special Report: Vocational Training in the High-Tech Age.

    ERIC Educational Resources Information Center

    Mansnerus, Laura; And Others

    1994-01-01

    "New Pressures on Vocational Education" (Mansnerus) describes new forms (tech prep, career academies, apprenticeship, school enterprises); "Biotechnology Goes to High School" (Quinn) describes Berkeley High's Biotech Academy created by industry; and "Votech That Works" (Holusha) stresses the importance of specialized training for non-college-bound…

  7. Satellite Power Systems (SPS) concept definition study, exhibit C. Volume 5: Special emphasis studies

    NASA Technical Reports Server (NTRS)

    Hanley, G.

    1979-01-01

    Specific areas were analyzed and identified as high priority for more in-depth analysis. These areas were: (1) rectenna constructability; (2) satellite constructability; (3) support systems constructability; (4) space environmental analysis, and (5) special end-to-end analyses. Baseline requirements specified coplanar solar blankets and an end mounted antenna, utilizing either GaAlAs solar cells and employing a CR of 2, or Si cells. Several configurations were analyzed. Utilizing the preferred configuration as a baseline, a satellite construction base was defined, precursor operations incident to establishment of orbital support facilities identified, and the satellite construction sequence and procedures developed. Since the baseline specifies sixty instead of one hundred and twenty satellites to be constructed in a thirty year period, mass flow to orbit requirements were revised and new traffic models established. Launch site requirements (exclusive of actual launch operations) in terms of manpower and building space were defined.

  8. Counselor Effectiveness: A Changing Emphasis

    ERIC Educational Resources Information Center

    Doyle, W. L.; Conklin, R. C.

    1970-01-01

    It is suggested that emphasis be changed from trait factor personality studies such as tolerance for ambiguity, nurturance, and abasement, to researching the area of cognitive style, flexibility, perception and psychological openness as perhaps being more fruitful in advancing knowledge of the criterion variable. (Author)

  9. Receptors and aging: dedicated to the memory of Paul Ehrlich for the 100th anniversary of his Nobel Prize.

    PubMed

    Robert, L; Labat-Robert, J; Robert, A M

    2010-01-01

    The initiation and evolution of the receptor concept and its application in pharmacology can be traced back to Paul Ehrlich's original experiments. Since several decades the receptor concept is in the foreground of cell biology and pharmacology. We present here a short reminder of Ehrlich's concepts on receptor action, its evolution and modifications as a result of increasing life expectancy of human societies. Results obtained by several teams on the age-dependent modifications of receptor function are reviewed with special emphasis on the age-dependent loss of receptors and of uncoupling of receptors from their intracellular transmission pathway. As a special example we summarize our results on the elastin receptor and its age-dependent modifications. These modifications result in the loss of the physiologically helpful functions mediated by this receptor, such as vasodilation by coupling with the inducible nitric oxide synthase (iNOS)-inhibition of cellular cholesterol synthesis and modulation of free radical production by inhibition of the guanine nucleotide binding protein (Gi protein)-mediated transmission pathway. Only the harmful effects such as free radical release and up-regulation of elastase production remain in "old" cells. The age-dependent modifications of receptor function play an important role in the increasing frequency and severity of age-related diseases such as athero-arteriosclerosis and emphysema as well as the loss of hormone- and drug actions. These processes and their inhibition or correction represent a new challenge for cellular pharmacology. Copyright © 2009 Elsevier Ireland Ltd. All rights reserved.

  10. Exercise and sleep in aging: emphasis on serotonin.

    PubMed

    Melancon, M O; Lorrain, D; Dionne, I J

    2014-10-01

    Reductions in central serotonin activity with aging might be involved in sleep-related disorders in later life. Although the beneficial effects of aerobic exercise on sleep are not new, sleep represents a complex recurring state of unconsciousness involving many lines of transmitters which remains only partly clear despite intense ongoing research. It is known that serotonin released into diencephalon and cerebrum might play a key inhibitory role to help promote sleep, likely through an active inhibition of supraspinal neural networks. Several lines of evidence support the stimulatory effects of exercise on higher serotonergic pathways. Hence, exercise has proved to elicit acute elevations in forebrain serotonin concentrations, an effect that waned upon cessation of exercise. While adequate exercise training might lead to adaptations in higher serotonergic networks (desensitization of forebrain receptors), excessive training has been linked to serious brain serotonergic maladaptations accompanied by insomnia. Dietary supplementation of tryptophan (the only serotonin precursor) is known to stimulate serotonergic activity and promote sleep, whereas acute tryptophan depletion causes deleterious effects on sleep. Regarding sleep-wake regulation, exercise has proved to accelerate resynchronization of the biological clock to new light-dark cycles following imposition of phase shifts in laboratory animals. Noteworthy, the effect of increased serotonergic transmission on wake state appears to be biphasic, i.e. promote wake and thereafter drowsiness. Therefore, it might be possible that acute aerobic exercise would act on sleep by increasing activity of ascending brain serotonergic projections, though additional work is warranted to better understand the implication of serotonin in the exercise-sleep axis. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  11. Mitochondrial dysfunction and sarcopenia of aging: from signaling pathways to clinical trials

    PubMed Central

    Marzetti, Emanuele; Calvani, Riccardo; Cesari, Matteo; Buford, Thomas W.; Lorenzi, Maria; Behnke, Bradley J.; Leeuwenburgh, Christiaan

    2013-01-01

    Sarcopenia, the age-related loss of muscle mass and function, imposes a dramatic burden on individuals and society. The development of preventive and therapeutic strategies against sarcopenia is therefore perceived as an urgent need by health professionals and has instigated intensive research on the pathophysiology of this syndrome. The pathogenesis of sarcopenia is multifaceted and encompasses lifestyle habits, systemic factors (e.g., chronic inflammation and hormonal alterations), local environment perturbations (e.g., vascular dysfunction), and intramuscular specific processes. In this scenario, derangements in skeletal myocyte mitochondrial function are recognized as major factors contributing to the age-dependent muscle degeneration. In this review, we summarize prominent findings and controversial issues on the contribution of specific mitochondrial processes – including oxidative stress, quality control mechanisms and apoptotic signaling – on the development of sarcopenia. Extramuscular alterations accompanying the aging process with a potential impact on myocyte mitochondrial function are also discussed. We conclude with presenting methodological and safety considerations for the design of clinical trials targeting mitochondrial dysfunction to treat sarcopenia. Special emphasis is placed on the importance of monitoring the effects of an intervention on muscle mitochondrial function and identifying the optimal target population for the trial. PMID:23845738

  12. Specialization patterns across various youth sports and relationship to injury risk.

    PubMed

    Pasulka, Jacqueline; Jayanthi, Neeru; McCann, Ashley; Dugas, Lara R; LaBella, Cynthia

    2017-09-01

    Current trends among young athletes towards earlier specialization age and year-round training on multiple teams has raised concern for increased injury risk. Our previous analyses showed higher risk for injury in highly specialized young athletes. The goal of this research was to determine whether sports specialization and injury patterns vary by sports type. In this clinical case-control study, injured athletes (aged 7-18 years) were recruited from sports medicine clinics and compared to similarly aged uninjured athletes recruited from primary care clinics. Participants completed a survey reporting age, gender, sport type, specialization patterns, and details regarding sports-related injuries in the previous 6 months. Clinical diagnoses were collected from patients' medical records. Injuries were classified as acute, overuse, or serious overuse. Of 1,190 athletes enrolled, 26% (313) were single-sport specialized (reported participation in one sport and trained >8 months/year). Sports with the highest proportion of single-sport specialized athletes were tennis (46.7%), gymnastics (30.1%), and dance (26.3%). Single-sport specialized athletes in individual sports started specializing at a younger age (11.2 ± 2.4 vs. 12.0 ± 2.7, p = 0.05) and reported higher training volumes (11.8 vs. 10.3 h/week, p = 0.04) than those in team sports. Sports with the youngest specialization age were gymnastics (8.9 ± 1.7), dance (10.8 ± 3.0), and soccer (10.9 ± 2.4). Single-sport specialized athletes in individual sports accounted for a higher proportion of overuse injuries (44.3% vs 32.2%, OR = 1.67, p = 0.037) and serious overuse injuries (23.4% vs 11.6%, OR = 2.38, p = 0.011), but a lower proportion of acute injuries (28.8% vs 13.8%, OR = 0.37, p = 0.001) compared to single-sport specialized athletes involved in team sports. Athletes in individual sports may be more likely to specialize in a single sport than team sport athletes. Single

  13. Engagement and Disengagement between Special and General Educators: An Application of Miles and Huberman's Cross-Case Analysis.

    ERIC Educational Resources Information Center

    Gersten, Russell; Marks, Susan Unok

    1998-01-01

    This cross-case analysis examined general education elementary-level teacher engagement with and effectiveness of "coaching," or expert consultation by special educators on effective teaching strategies. Factors resulting in high levels of impact on teaching and high levels of engagement were identified, including emphasis on conceptual…

  14. The Biology of Aging.

    ERIC Educational Resources Information Center

    Sprott, Richard L.; And Others

    1992-01-01

    Thirteen articles in this special issue discuss aging theories, biomarkers of aging, aging research, disease, cancer biology, Alzheimer's disease, stress, oxidation of proteins, gene therapy, service delivery, biogerontology, and ethics and aging research. (SK)

  15. Toy Play in Infancy and Early Childhood: Normal Development and Special Considerations for Children with Disabilities.

    ERIC Educational Resources Information Center

    1994

    This paper presents a review of the literature on toy play in infancy and early childhood, with an emphasis on both normal development and special considerations for young children with disabilities. Specifically, it describes children's encounters with toys within a developmental framework, identifies characteristics of the child and aspects of…

  16. Mitochondrial Oxidative Stress, Mitochondrial DNA Damage and Their Role in Age-Related Vascular Dysfunction

    PubMed Central

    Mikhed, Yuliya; Daiber, Andreas; Steven, Sebastian

    2015-01-01

    The prevalence of cardiovascular diseases is significantly increased in the older population. Risk factors and predictors of future cardiovascular events such as hypertension, atherosclerosis, or diabetes are observed with higher frequency in elderly individuals. A major determinant of vascular aging is endothelial dysfunction, characterized by impaired endothelium-dependent signaling processes. Increased production of reactive oxygen species (ROS) leads to oxidative stress, loss of nitric oxide (•NO) signaling, loss of endothelial barrier function and infiltration of leukocytes to the vascular wall, explaining the low-grade inflammation characteristic for the aged vasculature. We here discuss the importance of different sources of ROS for vascular aging and their contribution to the increased cardiovascular risk in the elderly population with special emphasis on mitochondrial ROS formation and oxidative damage of mitochondrial DNA. Also the interaction (crosstalk) of mitochondria with nicotinamide adenosine dinucleotide phosphate (NADPH) oxidases is highlighted. Current concepts of vascular aging, consequences for the development of cardiovascular events and the particular role of ROS are evaluated on the basis of cell culture experiments, animal studies and clinical trials. Present data point to a more important role of oxidative stress for the maximal healthspan (healthy aging) than for the maximal lifespan. PMID:26184181

  17. Buoyancy-generating agents for stomach-specific drug delivery: an overview with special emphasis on floating behavior.

    PubMed

    Ishak, Rania A H

    2015-01-01

    Gastric retentive drug delivery provides a promising technology exhibiting an extended gastric residence and a drug release independent of patient related variables. It is usually useful in improving local gastric treatment as well as overcoming drug-related problems .i.e. drugs having narrow absorption window, short half-life or low intestinal solubility. Buoyancy is considered one of the most promising approaches for gastro-retention of dosage forms. Floating drug delivery systems have a bulk density lower than gastric fluids and thus remain buoyant in the stomach causing an increase in gastric residence time. The buoyancy of these systems is attained by the aid of substances responsible to generate the low density. Various agents with different mechanisms were adopted either gas-generating agents, air entrapping swellable polymers, inherent low density substances, porous excipients, hollow/porous particles inducing preparation techniques or sublimating agents. Therefore, this review gives an exclusive descriptive classification of the different categories of these buoyancy-generating agents while representing the related research works. An overview is also conducted to describe relevant techniques assessing the floating behavior of such dosage forms either in vitro or in vivo. Finally, a collection representing FDA-approved floating pharmaceutical products is adopted with emphasis on the buoyancy-generating agent type used in each product.

  18. Differences in physical fitness and gross motor coordination in boys aged 6-12 years specializing in one versus sampling more than one sport.

    PubMed

    Fransen, Job; Pion, Johan; Vandendriessche, Joric; Vandorpe, Barbara; Vaeyens, Roel; Lenoir, Matthieu; Philippaerts, Renaat M

    2012-01-01

    The Developmental Model of Sports Participation proposes two pathways towards expertise in sports between 6 and 12 years of age: early specialization and early diversification. This study investigated the effect of sampling various sports and of spending many or few hours in sports on fitness and gross motor coordination. Altogether, 735 boys in three age groups (6-8, 8-10, and 10-12 years) were profiled using a fitness test battery. A computerized physical activity questionnaire was used to obtain data on sports participation. In the eldest group, (M)ANCOVA showed a positive effect of sampling various sports on strength, speed, endurance, and gross motor coordination (P < 0.05). A positive effect of many hours per week spent in sports was apparent in every age group. These data suggest an acute positive effect of many hours in sports and a latent positive effect of early sampling on fitness and gross motor coordination. Multiple comparisons revealed that boys aged 10-12 years, who spent many hours in various sports, performed better on standing broad jump (P < 0.05) and gross motor coordination (P < 0.05) than boys specializing in a single sport. Therefore, our results highlight the importance of spending many hours in sports and sampling various sports in the development of fitness and gross motor coordination.

  19. The Spanish Society of Neurology's official clinical practice guidelines for epilepsy. Special considerations in epilepsy: comorbidities, women of childbearing age, and elderly patients.

    PubMed

    Mauri Llerda, J A; Suller Marti, A; de la Peña Mayor, P; Martínez Ferri, M; Poza Aldea, J J; Gomez Alonso, J; Mercadé Cerdá, J M

    2015-10-01

    The characteristics of some population groups (patients with comorbidities, women of childbearing age, the elderly) may limit epilepsy management. Antiepileptic treatment in these patients may require adjustments. We searched articles in Pubmed, clinical practice guidelines for epilepsy, and recommendations by the most relevant medical societies regarding epilepsy in special situations (patients with comorbidities, women of childbearing age, the elderly). Evidence and recommendations are classified according to the prognostic criteria of Oxford Centre of Evidence-Based Medicine (2001) and the European Federation of Neurological Societies (2004) for therapeutic interventions. Epilepsy treatment in special cases of comorbidities must be selected properly to improve efficacy with the fewest side effects. Adjusting antiepileptic medication and/or hormone therapy is necessary for proper seizure management in catamenial epilepsy. Exposure to antiepileptic drugs (AED) during pregnancy increases the risk of birth defects and may affect fetal growth and/or cognitive development. Postpartum breastfeeding is recommended, with monitoring for adverse effects if sedative AEDs are used. Finally, the elderly are prone to epilepsy, and diagnostic and treatment characteristics in this group differ from those of other age groups. Although therapeutic limitations may be more frequent in older patients due to comorbidities, they usually respond better to lower doses of AEDs than do other age groups. Copyright © 2014 Sociedad Española de Neurología. Published by Elsevier España, S.L.U. All rights reserved.

  20. Communication Satellite Payload Special Check out Equipment (SCOE) for Satellite Testing

    NASA Astrophysics Data System (ADS)

    Subhani, Noman

    2016-07-01

    This paper presents Payload Special Check out Equipment (SCOE) for the test and measurement of communication satellite Payload at subsystem and system level. The main emphasis of this paper is to demonstrate the principle test equipment, instruments and the payload test matrix for an automatic test control. Electrical Ground Support Equipment (EGSE)/ Special Check out Equipment (SCOE) requirements, functions and architecture for C-band and Ku-band payloads are presented in details along with their interface with satellite during different phases of satellite testing. It provides test setup, in a single rack cabinet that can easily be moved from payload assembly and integration environment to thermal vacuum chamber all the way to launch site (for pre-launch test and verification).

  1. Chemistry through the language barrier. How to scan chemical articles in foreign languages with emphasis on Russian and Japanese

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Reid, E.E.

    1970-01-01

    The thesis of this book is that one can learn a surprising amount of information from scientific articles in a foreign language. Use is made of symbols, numbers, etc., (which appear in familiar Roman script) and words that are similar in many languages (e.g., reaction, reazione, reaccion, reactie, reaccao, reaktion, reaksjon, reaktionen, reakcio, rektio, reaktsiya, reakcja, and reakce). Most European languages (Germanic, Latin, et al.) are included, with special emphasis on Russian and Japanese. The technique is illustrated with examples from organic chemistry, but the approach should be applicable to scientific writing in any subject area. (RWR)

  2. Primary health-care costs associated with special health care needs up to age 7 years: Australian population-based study.

    PubMed

    Quach, Jon; Oberklaid, Frank; Gold, Lisa; Lucas, Nina; Mensah, Fiona K; Wake, Melissa

    2014-10-01

    We studied infants and children with and without special health care needs (SHCN) during the first 8 years of life to compare the (i) types and costs to the government's Medicare system of non-hospital health-care services and prescription medication in each year and (ii) cumulative costs according to persistence of SHCN. Data from the first two biennial waves of the nationally representative Longitudinal Study of Australian Children, comprising two independent cohorts recruited in 2004, at ages 0-1 (n = 5107) and 4-5 (n = 4983) years. Exposure condition: parent-reported Children with Special Health Care Needs Screener at both waves, spanning ages 0-7 years. Federal Government Medicare expenditure, via data linkage to the Medicare database, on non-hospital health-care attendances and prescriptions from birth to 8 years. At both waves and in both cohorts, >92% of children had complete SHCN and Medicare data. The proportion of children with SHCN increased from 6.1% at age 0-1 years to 15.0% at age 6-7 years. Their additional Medicare costs ranged from $491 per child at 6-7 years to $1202 at 0-1 year. This equates to an additional $161.8 million annual cost or 0.8% of federal funding for non-hospital-based health care. In both cohorts, costs were highest for children with persistent SHCNs. SHCNs incur substantial non-hospital costs to Medicare, and no doubt other sources of care, from early childhood. This suggests that economic evaluations of early prevention and intervention services for SHCNs should consider impacts on not only the child and family but also the health-care system. © 2014 The Authors. Journal of Paediatrics and Child Health © 2014 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

  3. Long-term influences of a preterm birth on movement organization and side specialization in children at 4-8 years of age.

    PubMed

    Johansson, Anna-Maria; Domellöf, Erik; Rönnqvist, Louise

    2014-09-01

    This study explored upper-limb and head kinematics during unimanual goal-directed movements in children born preterm (PT) and full-term (FT) aged 4-8 years. Further, functional lateralization was investigated through side-specific kinematics and hand preference observations. Altogether, 141 children were included, divided into three sub-groups based on gestation week at birth (GW). Children born FT (38-41 GW) and moderately PT (33-35 GW) showed faster, smoother, and shorter movement trajectories than children born very PT (V-PT < 33 GW). Only children born FT expressed evident side differences that were characterized by smoother movements with the preferred side. Regarding hand preference, the children born V-PT showed increased rates of non-right-handedness compared with the other groups. Regardless of hand preference, the children born V-PT showed less well organized movements compared with the other groups. These findings suggest that spatio-temporal movement organization and side specialization at pre-/early school-age are affected by a PT birth, and more frequently so for children born before 33 GWs, indicating long-lasting influences on neuromotor development and specialization. © 2014 Wiley Periodicals, Inc.

  4. 29 CFR 1625.31 - Special employment programs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 4 2013-07-01 2013-07-01 false Special employment programs. 1625.31 Section 1625.31 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION AGE DISCRIMINATION IN EMPLOYMENT ACT Administrative Exemptions § 1625.31 Special employment programs. (a) Pursuant to the authority...

  5. 29 CFR 1625.31 - Special employment programs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 4 2011-07-01 2011-07-01 false Special employment programs. 1625.31 Section 1625.31 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION AGE DISCRIMINATION IN EMPLOYMENT ACT Administrative Exemptions § 1625.31 Special employment programs. (a) Pursuant to the authority...

  6. 29 CFR 1625.31 - Special employment programs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 4 2014-07-01 2014-07-01 false Special employment programs. 1625.31 Section 1625.31 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION AGE DISCRIMINATION IN EMPLOYMENT ACT Administrative Exemptions § 1625.31 Special employment programs. (a) Pursuant to the authority...

  7. 29 CFR 1625.31 - Special employment programs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Special employment programs. 1625.31 Section 1625.31 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION AGE DISCRIMINATION IN EMPLOYMENT ACT Administrative Exemptions § 1625.31 Special employment programs. (a) Pursuant to the authority...

  8. 29 CFR 1625.31 - Special employment programs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 4 2012-07-01 2012-07-01 false Special employment programs. 1625.31 Section 1625.31 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION AGE DISCRIMINATION IN EMPLOYMENT ACT Administrative Exemptions § 1625.31 Special employment programs. (a) Pursuant to the authority...

  9. Current and Emerging Forces Impacting Special Education.

    ERIC Educational Resources Information Center

    Yates, James R.

    Using the methodology of force field analysis, the paper develops possible futures for special education based on current trends. Demographic forces impacting special education include age changes, ethnicity changes, the needs of emerging language minorities, specific change in the youth population, environmental factors and the incidence of…

  10. Older drivers, the age factor in traffic safety

    DOT National Transportation Integrated Search

    1989-02-01

    The report presents an overview of the traffic safety problem in relation to the age of the driver. Emphasis is placed on the older drivers. Crash involvement rates are developed for each age group of drivers based on their estimated annual travel. T...

  11. Individual specialization in diet by a generalist marine predator reflects specialization in foraging behaviour.

    PubMed

    Woo, Kerry J; Elliott, Kyle Hamish; Davidson, Melissa; Gaston, Anthony J; Davoren, Gail K

    2008-11-01

    1. We studied chick diet in a known-age, sexed population of a long-lived seabird, the Brünnich's guillemot (Uria lomvia), over 15 years (N = 136; 1993-2007) and attached time-depth-temperature recorders to examine foraging behaviour in multiple years (N = 36; 2004-07). 2. Adults showed specialization in prey fed to offspring, described by multiple indices calculated over 15 years: 27% of diet diversity was attributable to among-individual variation (within-individual component of total niche width = 0.73); average similarity of an individual's diet to the overall diet was 65% (mean proportional similarity between individuals and population = 0.65); diet was significantly more specialized than expected for 70% of individuals (mean likelihood = 0.53). These indices suggest higher specialization than the average for an across-taxa comparison of 49 taxa. 3. Foraging behaviour varied along three axes: flight time, dive depth and dive shape. Individuals showed specialized individual foraging behaviour along each axis. These foraging strategies were reflected in the prey type delivered to their offspring and were maintained over scales of hours to years. 4. Specialization in foraging behaviour and diet was greater over short time spans (hours, days) than over long time spans (years). Regardless of sex or age, the main component of variation in foraging behaviour and chick diet was between individuals. 5. Plasma stable isotope values were similar across years, within a given individual, and variance was low relative to that expected from prey isotope values, suggesting adult diet specialized across years. Stable isotope values were similar among individuals that fed their nestlings similar prey items and there was no difference in trophic level between adults and chicks. We suggest that guillemots specialize on a single foraging strategy regardless of whether chick-provisioning and self-feeding. With little individual difference in body mass and physiology

  12. Sport Specialization, Part I: Does Early Sports Specialization Increase Negative Outcomes and Reduce the Opportunity for Success in Young Athletes?

    PubMed

    Myer, Gregory D; Jayanthi, Neeru; Difiori, John P; Faigenbaum, Avery D; Kiefer, Adam W; Logerstedt, David; Micheli, Lyle J

    2015-01-01

    There is increased growth in sports participation across the globe. Sports specialization patterns, which include year-round training, participation on multiple teams of the same sport, and focused participation in a single sport at a young age, are at high levels. The need for this type of early specialized training in young athletes is currently under debate. Nonsystematic review. Clinical review. Level 4. Sports specialization is defined as year-round training (greater than 8 months per year), choosing a single main sport, and/or quitting all other sports to focus on 1 sport. Specialized training in young athletes has risks of injury and burnout, while the degree of specialization is positively correlated with increased serious overuse injury risk. Risk factors for injury in young athletes who specialize in a single sport include year-round single-sport training, participation in more competition, decreased age-appropriate play, and involvement in individual sports that require the early development of technical skills. Adults involved in instruction of youth sports may also put young athletes at risk for injury by encouraging increased intensity in organized practices and competition rather than self-directed unstructured free play. C. © 2015 The Author(s).

  13. Mental Health among Former Students with Special Educational Needs Who Are Now in Their Mid-30s

    ERIC Educational Resources Information Center

    Myklebust, Jon; Myklebust, Vidar

    2017-01-01

    This article discusses how psychosocial health in adolescence influences adult mental health among former students with special educational needs in Norway. These individuals have been followed prospectively from their teens and into their mid-30s. The study is inspired by life course perspectives with an emphasis on cumulative processes. The…

  14. Sports Specialization in Young Athletes

    PubMed Central

    Jayanthi, Neeru; Pinkham, Courtney; Dugas, Lara; Patrick, Brittany; LaBella, Cynthia

    2013-01-01

    Context: Sports specialization is intense training in 1 sport while excluding others. Sports specialization in early to middle childhood has become increasingly common. While most experts agree that some degree of sports specialization is necessary to achieve elite levels, there is some debate as to whether such intense practice time must begin during early childhood and to the exclusion of other sports to maximize potential for success. There is a concern that sports specialization before adolescence may be deleterious to a young athlete. Evidence Acquisition: PubMed and OVID were searched for English-language articles from 1990 to 2011 discussing sports specialization, expert athletes, or elite versus novice athletes, including original research articles, consensus opinions, and position statements. Results: For most sports, there is no evidence that intense training and specialization before puberty are necessary to achieve elite status. Risks of early sports specialization include higher rates of injury, increased psychological stress, and quitting sports at a young age. Sports specialization occurs along a continuum. Survey tools are being developed to identify where athletes fall along the spectrum of specialization. Conclusion: Some degree of sports specialization is necessary to develop elite-level skill development. However, for most sports, such intense training in a single sport to the exclusion of others should be delayed until late adolescence to optimize success while minimizing injury, psychological stress, and burnout. PMID:24427397

  15. An overview on "cellular cannibalism" with special reference to oral squamous cell carcinoma.

    PubMed

    Jain, M

    2015-12-01

    Cellular cannibalism has been defined as a large cell engulfing a slightly smaller one within its cytoplasm. It has been described in various cancers like bladder cancer, breast cancer, lung cancer, gastric cancer, oral squamous cell carcinoma. Cellular cannibalism has been well correlated with anaplasia, tumor aggressiveness, grading and metastatic potential. Present review focuses on significance of cannibalism in relation to cancer with special emphasis on oral squamous cell carcinoma.

  16. Relationship between bone turnover markers and the heel stiffness index measured by quantitative ultrasound in middle-aged and elderly Japanese men

    PubMed Central

    Nishimura, Takayuki; Arima, Kazuhiko; Abe, Yasuyo; Kanagae, Mitsuo; Mizukami, Satoshi; Okabe, Takuhiro; Tomita, Yoshihito; Goto, Hisashi; Horiguchi, Itsuko; Aoyagi, Kiyoshi

    2018-01-01

    Abstract The aim of the present study was to investigate the age-related patterns and the relationships between serum levels of tartrate-resistant acid phosphatase-5b (TRACP-5b) or bone-specific alkaline phosphatase (BAP), and the heel stiffness index measured by quantitative ultrasound (QUS) in 429 Japanese men, with special emphasis on 2 age groups (40–59 years and 60 years or over). The heel stiffness index (bone mass) was measured by QUS. Serum samples were collected, and TRACP-5b and BAP levels were measured. The stiffness index was significantly decreased with age. Log (TRACP-5b) was significantly increased with age, but Log (BAP) was stable. Generalized linear models showed that higher levels of Log (TRACP-5b) and Log (BAP) were correlated with a lower stiffness index after adjusting for covariates in men aged 60 years or over, but not in men aged 40 to 59 years. In conclusion, higher rates of bone turnover markers were associated with a lower stiffness index only in elderly men. These results may indicate a different mechanism of low bone mass among different age groups of men. PMID:29465590

  17. Getting Older: The Special Child Grows Up.

    ERIC Educational Resources Information Center

    Smith, H. Carlton; And Others

    1992-01-01

    This newsletter issue focuses on the specific concerns of many parents as their special child "ages out" of protected special education environments and moves into the adult world. It highlights the practical aspects of the transition years as well as the emotional components involved in "letting go." The newsletter's articles…

  18. The Public Community College in America: Its History, Present Condition, and Future Outlook with Special Reference to Finance.

    ERIC Educational Resources Information Center

    Edwards, Nancy Joan

    The development, current status, and future prospects of community colleges are examined in this study with special emphasis on finance and funding concerns. Introductory material outlines study objectives, methodology, and purposes; defines key terms; and emphasizes the importance of college planning. Chapter 1 presents a history of the community…

  19. 77 FR 50517 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-21

    ...: Neuroimmunity, brain tumors, obesity in aging. Date: September 6, 2012. Time: 11:00 a.m. to 1:00 p.m. Agenda: To... . Name of Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: Aging, Diet...

  20. Mortality and morbidity in the city of Bern, Switzerland, 1805-1815 with special emphasis on infant, child and maternal deaths.

    PubMed

    Rüttimann, D; Loesch, S

    2012-02-01

    This article contributes to the research on demographics and public health of urban populations of preindustrial Europe. The key source is a burial register that contains information on the deceased, such as age and sex, residence and cause of death. This register is one of the earliest compilations of data sets of individuals with this high degree of completeness and consistency. Critical assessment of the register's origin, formation and upkeep promises high validity and reliability. Between 1805 and 1815, 4,390 deceased inhabitants were registered. Information concerning these individuals provides the basis for this study. Life tables of Bern's population were created using different models. The causes of death were classified and their frequency calculated. Furthermore, the susceptibility of age groups to certain causes of death was established. Special attention was given to causes of death and mortality of newborns, infants and birth-giving women. In comparison to other cities and regions in Central Europe, Bern's mortality structure shows low rates for infants (q0=0.144) and children (q1-4=0.068). This could have simply indicated better living conditions. Life expectancy at birth was 43 years. Mortality was high in winter and spring, and decreased in summer to a low level with a short rise in August. The study of the causes of death was inhibited by difficulties in translating early 19th century nomenclature into the modern medical system. Nonetheless, death from metabolic disorders, illnesses of the respiratory system, and debilitation were the most prominent causes in Bern. Apparently, the worst killer of infants up to 12 months was the "gichteren", an obsolete German term for lethal spasmodic convulsions. The exact modern identification of this disease remains unclear. Possibilities such as infant tetanus or infant epilepsy are discussed. The maternal death rate of 0.72% is comparable with values calculated from contemporaneous sources. Relevance of

  1. WORKMEN'S COMPENSATION—Emphasis on Rehabilitation

    PubMed Central

    Shepard, William P.

    1956-01-01

    Since the first law was enacted in 1911 major emphasis has been placed on monetary satisfaction of liability with insufficient attention to rehabilitation of the occupationally disabled. An effective workmen's compensation program must have three basic goals: (1) Rehabilitation of the occupationally disabled; (2) assured, prompt, and adequate indemnity for the occupationally disabled or their survivors; and (3) minimal costs to employers and society commensurate with the first two goals. It is suggested that the medical societies of each state provide a broadly representative committee to advise the administrative agency on medical policies and practices. This committee would prepare registers of all physicians in each locality who are willing and qualified to accept calls for service to injured employees, would mediate complaints originating with the employee, the employer, the insurance carrier or the administrative agency, and would cooperate with the administrative agency in educational programs for all concerned. It is the physician's responsibility to help the administrative agency in shifting the emphasis from indemnity to rehabilitation. The disabled employee is entitled to all services available to restore him to an earning capacity. PMID:13356180

  2. Pruning or tuning? Maturational profiles of face specialization during typical development.

    PubMed

    Zhu, Xun; Bhatt, Ramesh S; Joseph, Jane E

    2016-06-01

    Face processing undergoes significant developmental change with age. Two kinds of developmental changes in face specialization were examined in this study: specialized maturation, or the continued tuning of a region to faces but little change in the tuning to other categories; and competitive interactions, or the continued tuning to faces accompanied by decreased tuning to nonfaces (i.e., pruning). Using fMRI, in regions where adults showed a face preference, a face- and object-specialization index were computed for younger children (5-8 years), older children (9-12 years) and adults (18-45 years). The specialization index was scaled to each subject's maximum activation magnitude in each region to control for overall age differences in the activation level. Although no regions showed significant face specialization in the younger age group, regions strongly associated with social cognition (e.g., right posterior superior temporal sulcus, right inferior orbital cortex) showed specialized maturation, in which tuning to faces increased with age but there was no pruning of nonface responses. Conversely, regions that are associated with more basic perceptual processing or motor mirroring (right middle temporal cortex, right inferior occipital cortex, right inferior frontal opercular cortex) showed competitive interactions in which tuning to faces was accompanied by pruning of object responses with age. The overall findings suggest that cortical maturation for face processing is regional-specific and involves both increased tuning to faces and diminished response to nonfaces. Regions that show competitive interactions likely support a more generalized function that is co-opted for face processing with development, whereas regions that show specialized maturation increase their tuning to faces, potentially in an activity-dependent, experience-driven manner.

  3. Aging and older adults in three Roman Catholic magazines: Successful aging and the Third and Fourth Ages reframed.

    PubMed

    Sawchuk, Dana

    2015-12-01

    This article is a qualitative content analysis of how aging and older adults are represented in the articles of three Roman Catholic magazines in the United States: America, Commonweal, and U.S. Catholic. The findings suggest that, as in mainstream secular magazines, the concept of successful aging is common in portrayals of older adults in the Third Age. Distinctive in Catholic magazine portrayals of successful aging is an emphasis on meaningful activity and on the wisdom that is gained and transmitted in this stage of life. In contrast to the lack of attention to Fourth Age decline in mainstream magazines, in the Catholic publications the difficult features of such deterioration are acknowledged but are also reframed as potential sources of value. The theoretical implications of these more complex faith-based renderings of the Third and Fourth Ages are briefly explored. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. 14 CFR 1252.203 - Special benefits for children and the elderly.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... elderly. 1252.203 Section 1252.203 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION... Determining Age Discrimination § 1252.203 Special benefits for children and the elderly. If a recipient operating a program or activity provides special benefits to the elderly or to children, such use of age...

  5. 14 CFR 1252.203 - Special benefits for children and the elderly.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... elderly. 1252.203 Section 1252.203 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION... Determining Age Discrimination § 1252.203 Special benefits for children and the elderly. If a recipient operating a program or activity provides special benefits to the elderly or to children, such use of age...

  6. Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics

    PubMed Central

    Marzetti, Emanuele; Csiszar, Anna; Dutta, Debapriya; Balagopal, Gauthami; Calvani, Riccardo

    2013-01-01

    Advanced age is associated with a disproportionate prevalence of cardiovascular disease (CVD). Intrinsic alterations in the heart and the vasculature occurring over the life course render the cardiovascular system more vulnerable to various stressors in late life, ultimately favoring the development of CVD. Several lines of evidence indicate mitochondrial dysfunction as a major contributor to cardiovascular senescence. Besides being less bioenergetically efficient, damaged mitochondria also produce increased amounts of reactive oxygen species, with detrimental structural and functional consequences for the cardiovascular system. The age-related accumulation of dysfunctional mitochondrial likely results from the combination of impaired clearance of damaged organelles by autophagy and inadequate replenishment of the cellular mitochondrial pool by mitochondriogenesis. In this review, we summarize the current knowledge about relevant mechanisms and consequences of age-related mitochondrial decay and alterations in mitochondrial quality control in the cardiovascular system. The involvement of mitochondrial dysfunction in the pathogenesis of cardiovascular conditions especially prevalent in late life and the emerging connections with neurodegeneration are also illustrated. Special emphasis is placed on recent discoveries on the role played by alterations in mitochondrial dynamics (fusion and fission), mitophagy, and their interconnections in the context of age-related CVD and endothelial dysfunction. Finally, we discuss pharmacological interventions targeting mitochondrial dysfunction to delay cardiovascular aging and manage CVD. PMID:23748424

  7. What is special about Cygnus X-1?. [evidence for a black hole

    NASA Technical Reports Server (NTRS)

    Boldt, E. A.; Holt, S. S.; Rothschild, R. E.; Serlemitsos, P. J.

    1974-01-01

    The X-ray evidence from several experiments is reviewed, with special emphasis on those characteristics which appear to distinguish Cygnus X-1 from other compact X-ray emitting objects. Data are examined within the context of a model in which millisecond bursts are superposed upon shot-noise fluctuations arising from events of durations on the order of a second. Possible spectral-temporal correlations are investigated which provide additional evidence that Cygnus X-1 is very likely a black hole.

  8. 76 FR 27327 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Combining...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-11

    ... Objective Methods for Quantifying Contact Rates and Mixing Pattern in School-Aged Children, Funding... follows: Time And Date: 11 a.m.-2 p.m., May 3, 2011 (Closed). Place: Teleconference. Contact Person For...

  9. Gastric lymphomas in Turkey. Analysis of prognostic factors with special emphasis on flow cytometric DNA content.

    PubMed

    Aydin, Z D; Barista, I; Canpinar, H; Sungur, A; Tekuzman, G

    2000-07-01

    In contrast to DNA ploidy, to the authors' knowledge the prognostic significance of S-phase fraction (SPF) in gastric lymphomas has not been determined. In the current study, the prognostic significance of various parameters including SPF and DNA aneuploidy were analyzed and some distinct epidemiologic and biologic features of gastric lymphomas in Turkey were found. A series of 78 gastric lymphoma patients followed at Hacettepe University is reported. DNA flow cytometry was performed for 34 patients. The influence of various parameters on survival was investigated with the log rank test. The Cox proportional hazards model was fitted to identify independent prognostic factors. The median age of the patients was 50 years. There was no correlation between patient age and tumor grade. DNA content analysis revealed 4 of the 34 cases to be aneuploid with DNA index values < 1.0. The mean SPF was 33.5%. In the univariate analysis, surgical resection of the tumor, modified Ann Arbor stage, performance status, response to first-line chemotherapy, lactate dehydrogenase (LDH) level, and SPF were important prognostic factors for disease free survival (DFS). The same parameters, excluding LDH level, were important for determining overall survival (OS). In the multivariate analysis, surgical resection of the tumor, disease stage, performance status, and age were found to be important prognostic factors for OS. To the authors' knowledge the current study is the first to demonstrate the prognostic significance of SPF in gastric lymphomas. The distinguishing features of Turkish gastric lymphoma patients are 1) DNA indices of aneuploid cases that all are < 1.0, which is a unique feature; 2) a lower percentage of aneuploid cases; 3) a higher SPF; 4) a younger age distribution; and 5) lack of an age-grade correlation. The authors conclude that gastric lymphomas in Turkey have distinct biologic and epidemiologic characteristics. Copyright 2000 American Cancer Society.

  10. Specialized Meaninglessness: A Source of Truth in the Technical Age.

    ERIC Educational Resources Information Center

    Thompson, Mark E.

    This essay discusses how technical processes can deceive us and how college educators and social scientists must be especially sensitive to the dangers of technology when conducting research and proposing applications from research. As technology and bureaucratic controls have grown, so too have the demands for specialized knowledge in many areas.…

  11. 34 CFR 674.51 - Special definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    .... (c) Title I Children: Children of ages 5 through 17 who are counted under section 1124(c)(1) of the Elementary and Secondary Education Act of 1965, as amended. (d) Child with a disability: A child or youth... mitigation (HAZMAT). (l) Handicapped children: Children of ages 3 through 21 inclusive who require special...

  12. 34 CFR 674.51 - Special definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... (c) Title I Children: Children of ages 5 through 17 who are counted under section 1124(c)(1) of the Elementary and Secondary Education Act of 1965, as amended. (d) Child with a disability: A child or youth... mitigation (HAZMAT). (l) Handicapped children: Children of ages 3 through 21 inclusive who require special...

  13. 34 CFR 674.51 - Special definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    .... (c) Title I Children: Children of ages 5 through 17 who are counted under section 1124(c)(1) of the Elementary and Secondary Education Act of 1965, as amended. (d) Child with a disability: A child or youth... mitigation (HAZMAT). (l) Handicapped children: Children of ages 3 through 21 inclusive who require special...

  14. 34 CFR 674.51 - Special definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    .... (c) Title I Children: Children of ages 5 through 17 who are counted under section 1124(c)(1) of the Elementary and Secondary Education Act of 1965, as amended. (d) Child with a disability: A child or youth... mitigation (HAZMAT). (l) Handicapped children: Children of ages 3 through 21 inclusive who require special...

  15. 34 CFR 674.51 - Special definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    .... (c) Title I Children: Children of ages 5 through 17 who are counted under section 1124(c)(1) of the Elementary and Secondary Education Act of 1965, as amended. (d) Child with a disability: A child or youth... mitigation (HAZMAT). (l) Handicapped children: Children of ages 3 through 21 inclusive who require special...

  16. In the Shadow: Chinese Special Forces Build a 21st-Century Fighting Force

    DTIC Science & Technology

    2006-07-01

    special forces began taking place in the late 1980s and early 1990s.1 The People’s Liberation Army, or PLA, has concentrated on selecting the highest...quality individuals within the military, providing them with the most advanced equipment available, and training them in a wide range of military...disciplines. The PLA has placed a high degree of emphasis on the physical and mental abilities of the candidates: The training can be grueling, and

  17. The Power of Mentoring: An Age-Old Strategy Is Helping Today's Youth.

    ERIC Educational Resources Information Center

    National Media Outreach Center.

    This collection of articles is one of several published by public television's "One PLUS One" project, a special media emphasis on mentoring and its effectiveness in helping young people. The articles reflect the belief that providing youth with adult support and guidance can strengthen their self-esteem and encourage them to achieve. The…

  18. 78 FR 5184 - Special Emphasis Panel Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-24

    ... ``Patient Centered Outcomes Research (PCOR) Pathway to Independence Award (K99/R00)''. DATES: February 12... Outcomes Research (PCOR) Pathway to Independence Award (K99/R00)'' are to be reviewed and discussed at this...

  19. 77 FR 55477 - Special Emphasis Panel Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-10

    ... Dissemination of Evidence-Based Medicine (R24)'' are to be reviewed and discussed at this meeting. The grant... Panel (SEP) meeting on ``Partnerships for Sustainable Research and Dissemination of Evidence-Based Medicine (R24)''. DATES: September 20-21, 2012 (Open on September 20 from 8:00 a.m. to 8:15 a.m. and closed...

  20. 75 FR 27351 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-14

    ... Committee: Biology of Development and Aging Integrated Review Group; Development--2 Study Section. Date...: Center for Scientific Review Special Emphasis Panel; ARRA: Developmental Brain Disorders Competitive...

  1. Aging and Cerebral Palsy.

    ERIC Educational Resources Information Center

    Networker, 1993

    1993-01-01

    This special edition of "The Networker" contains several articles focusing on aging and cerebral palsy (CP). "Aging and Cerebral Palsy: Pathways to Successful Aging" (Jenny C. Overeynder) reports on the National Invitational Colloquium on Aging and Cerebral Palsy held in April 1993. "Observations from an Observer" (Kathleen K. Barrett) describes…

  2. Successful ageing: from cell to self.

    PubMed Central

    Lupien, S J; Wan, N

    2004-01-01

    Many people see ageing as a time of cognitive and physical decline. For the past three decades, most scientists and the general public have accepted this negative age-stereotype as the norm, but fortunately this view is now challenged. New findings show that well-being and a positive view of ageing are major protective factors against the effects of age on the organism. These results challenge the scientific studies that place emphasis on the negative side of ageing. This ageism view has been observed in each sphere of science, from genetics to social sciences. Perspectives from each domain are described, and new integrative views of successful ageing are summarized. PMID:15347532

  3. 20 CFR 404.260 - Special minimum primary insurance amounts.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... 404.260 Section 404.260 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Computing Primary Insurance Amounts Special Minimum Primary... compute your primary insurance amount, if the special minimum primary insurance amount described in § 404...

  4. 77 FR 9675 - Center for Scientific Review: Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-17

    ...; Fellowships: Physiology and Pathobiology of Musculoskeletal, Oral, and Skin Systems. Date: March 14, 2012... Special Emphasis Panel; Small Business: Molecular and Cellular Neuroscience, Development and Aging Biology...

  5. 77 FR 14028 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-08

    ....gov . Name of Committee: Center for Scientific Review Special Emphasis Panel; Biological Chemistry and...-1323, [email protected] . Name of Committee: Biology of Development and Aging Integrated Review...

  6. College Students' Science Societies and Special-Interest Circles

    ERIC Educational Resources Information Center

    Ivanov, A.

    2005-01-01

    From the point of view of their age, student science societies and special-interest circles are among the most venerable forms of corporate association among students in colleges and universities. In this article, the author traces the formation of different societies and special-interest circles by college students in different universities in…

  7. 20 CFR 416.1261 - Application of special resource provision.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Application of special resource provision. 416.1261 Section 416.1261 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Resources and Exclusions § 416.1261 Application of special...

  8. 76 FR 28236 - National Institute on Aging; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... Emphasis Panel, Oxidative Stress and Aging. Date: July 13, 2011. Time: 12 p.m. to 4 p.m. Agenda: To review... Domestic Assistance Program Nos. 93.866, Aging Research, National Institutes of Health, HHS) Dated: May 10...

  9. An Inventory of International Clearing House Services in Population/Family Planning With Special Reference to Audio-Visual Aids and Educational Materials.

    ERIC Educational Resources Information Center

    Radel, David

    This paper provides an inventory and summary of current and planned international information clearing house services in the field of population/family planning, worldwide. Special emphasis is placed on services relating to audio-visual aids, educational materials, and information/education/communication support, as these items and activities have…

  10. Big Dreams, Special Needs

    ERIC Educational Resources Information Center

    Scheib, Michele

    2007-01-01

    Research suggests that 40 percent of college-age students with disabilities in the United States are enrolled in community colleges. Two-year colleges for a long time have been billed as ideal places for students with special needs to continue their educations, especially when those needs dictate that they remain closer to home. However, some…

  11. Pre-emphasis determination for an S-band constant bandwidth FM/FM station

    NASA Technical Reports Server (NTRS)

    Wallace, G. R.; Salter, W. E.

    1972-01-01

    Pre-emphasis schedules are given for 11 constant-bandwidth FM subcarriers modulating an S band transmitter at three receiver signal to noise ratios (i.e., 9, 15, and 25 dB). The criterion for establishing these pre-emphasis curves is the achievement, at various receiver intermediate frequency signal to noise ratios, of equal receiver output signal to noise ratios for all channels. It is realized that these curves may not be the optimum pre-emphasis curves based on overall efficiency or maximum utilization of the allotted spectrum, but they are near-optimum for data with channels which require equal output signal to noise ratios, such as spectral densities. The empirically derived results are compared with a simplified, analytically derived schedule and the primary differences are explained. The S band pre-emphasis schedule differs from the lower frequency VHF case. Since most proportional bandwidth and constant bandwidth systems use ground based recorders and some use flight recorders (as the Saturn systems did on VHF proportional bandwidth telemetry), the effects of these recorders are discussed and a modified pre-emphasis schedule is presented showing the results of this study phase.

  12. Traffic Safety for Special Children

    ERIC Educational Resources Information Center

    Wilson, Val; MacKenzie, R. A.

    1974-01-01

    In a 6 weeks' unit on traffic education using flannel graphs, filmstrips and models, 12 special class students (IQ 55-82) ages 7- to 11-years-old learned six basic skills including crossing a road, obeying traffic lights and walking on country roads. (CL)

  13. Orientation to Trades and Technology. A Curriculum Guide and Resource Book with Special Emphasis on the Needs of Women. Revised.

    ERIC Educational Resources Information Center

    Braundy, Marcia

    This combination curriculum guide and resource book was developed in response to recommendations made by the instructors who attended the Women in Trades and Technology (WITT) conference of June 1986. It assists in the design and delivery of exploratory trade and technology courses that are responsive to the special needs of women learners…

  14. Early Children's Literature and Aging

    ERIC Educational Resources Information Center

    McGuire, Sandra L.

    2016-01-01

    Increased longevity is a worldwide phenomenon placing emphasis on the need for preparation for life's later years. Today's children will be the older adults of tomorrow. A resource that can help to educate them about aging and prepare them for the long life ahead is early children's literature (Preschool-Primary). This literature can provide…

  15. QuickStats: Percentage* of Adults Aged ≥18 Years Who Cannot or Find It Very Difficult to Stand or Be on Their Feet for About 2 Hours Without Using Special Equipment,† by Age Group and Sex - National Health Interview Survey,§ United States, 2015.

    PubMed

    2016-12-02

    A reported 10.2% of adults aged ≥18 years cannot, or find it very difficult to, stand or be on their feet for about 2 hours without using special equipment. The percentage of adults who reported this difficulty increased with age: 2.9% of those aged 18-44 years, 11.8% of those aged 45-64 years, 19.1% of those 65-74 years, and 33.2% of those aged ≥75 years. Overall, women were more likely (11.9%) than men (8.3%) to report this difficulty, and higher percentages were noted for women within each age group.

  16. Innovative Solutions for Words with Emphasis: Alternative Methods of Braille Transcription

    ERIC Educational Resources Information Center

    Kamei-Hannan, Cheryl

    2009-01-01

    The author of this study proposed two alternative methods for transcribing words with emphasis into braille and compared the use of the symbols for emphasis with the current braille code. The results showed that students were faster at locating words presented in one of the alternate formats, but that there was no difference in students' accuracy…

  17. Space age. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1998-05-01

    Space age had its world premiere at the large-screen Spaceport Theater at Cape Canaveral/Kennedy Spaceport. The first program was screened for invited guests who, that morning, also witnessed a launch of the Space Shuttle. Since that mission carried the first Japanese astronaut, it was a nice tie-in to the substantial co-production participation of space age by NHK Japan. A special press conference for the series and a twenty-minute preview reel was screened for journalists who were also at the Cape for the shuttle launch. Numerous first-hand newspaper articles were generated. CNN ran part of the preview reel. The first episodemore » in the series, `The Quest for Planet Mars,` then ran twice a day for a week, prior to the Public Broadcasting Service broadcast on an Imax format screen at the Spaceport theater. The program was seen by thousands of visitors. Space age also had a special premier at the National Academy of Sciences in Washington, DC with some 400 special guests, including scientists and government agency representatives.« less

  18. Typical and atypical neurodevelopment for face specialization: An fMRI study

    PubMed Central

    Joseph, Jane E.; Zhu, Xun; Gundran, Andrew; Davies, Faraday; Clark, Jonathan D.; Ruble, Lisa; Glaser, Paul; Bhatt, Ramesh S.

    2014-01-01

    Individuals with Autism Spectrum Disorder (ASD) and their relatives process faces differently from typically developed (TD) individuals. In an fMRI face-viewing task, TD and undiagnosed sibling (SIB) children (5–18 years) showed face specialization in the right amygdala and ventromedial prefrontal cortex (vmPFC), with left fusiform and right amygdala face specialization increasing with age in TD subjects. SIBs showed extensive antero-medial temporal lobe activation for faces that was not present in any other group, suggesting a potential compensatory mechanism. In ASD, face specialization was minimal but increased with age in the right fusiform and decreased with age in the left amygdala, suggesting atypical development of a frontal-amygdala-fusiform system which is strongly linked to detecting salience and processing facial information. PMID:25479816

  19. EMPHASIS(TM)/Nevada UTDEM User Guide Version 2.1.1.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Turner, C. David; Pasik, Michael F.; Pointon, Timothy D.

    The Unstructured Time - Domain ElectroMagnetics (UTDEM) portion of the EMPHASIS suite solves Maxwell's equations using finite - element techniques on unstructured meshes. This document provides user - specific information to facilitate the use of the code for ap plications of interest. Acknowledgement The authors would like to thank all of those individuals who have helped to bring EMPHASIS/Nevada to the point it is today, including Bill Bohnhoff, Rich Drake, and all of the NEVADA code team.

  20. Project International Emphasis Interim Report, July 1991.

    ERIC Educational Resources Information Center

    Blois, Beverly, Ed.; Williams, Barbara

    Project International Emphasis (PIE), a curriculum development effort involving all 24 colleges in the Virginia Community College System (VCCS), focuses on the infusion of globally oriented components across the academic curriculum and in related career development programs. Activities undertaken during the project's first year included an annual…

  1. Preservice special education teachers' understandings, enactments, views, and plans for scientific inquiry: Issues and hopes

    NASA Astrophysics Data System (ADS)

    Ghosh, Rajlakshmi

    This study examined the understandings, enactments, views, and plans for scientific inquiry held by preservice special education teachers enrolled in a K--8 general science methods course. Sixteen participants from four special education concentration areas---Mild to Moderate Educational Needs, Moderate to Intense Educational Needs, Mild to Moderate Educational Needs with Language Arts and Reading Emphasis, and Early Childhood Intervention---participated in this study. Qualitative data were collected from questionnaires, interviews, teaching videos, lesson plans, planning commentaries, and reflection papers. Data were analyzed using a grounded theory approach (Strauss & Corbin, 1990) and compared against the theoretical view of inquiry as conceptualized by the National Research Council (NRC, 2000). The participants held unique interpretations of inquiry that only partially matched with the theoretical insights provided by the NRC. The participants' previous science learning experiences and experiences in special education played an important role in shaping their conceptualizations of inquiry as learned in the science methods class. The impacts of such unique interpretations are discussed with reference to both science education and special education, and implications for teacher education are provided.

  2. 45 CFR 91.17 - Special benefits for children and the elderly.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Special benefits for children and the elderly. 91... Standards for Determining Age Discrimination § 91.17 Special benefits for children and the elderly. If a recipient operating a program or activity provides special benefits to the elderly or to children, such use...

  3. 45 CFR 91.17 - Special benefits for children and the elderly.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Special benefits for children and the elderly. 91... Standards for Determining Age Discrimination § 91.17 Special benefits for children and the elderly. If a recipient operating a program or activity provides special benefits to the elderly or to children, such use...

  4. Problem of ticks and tick-borne diseases in India with special emphasis on progress in tick control research: a review.

    PubMed

    Ghosh, Srikant; Nagar, Gaurav

    2014-12-01

    Ticks, as vectors of several zoonotic diseases, are ranked second only to mosquitoes as vectors. The diseases spread by ticks are a major constraint to animal productivity while causing morbidity and mortality in both animals and humans. A number of tick species have been recognised since long as vectors of lethal pathogens, viz. Crimean-Congo haemorrhagic fever virus (CCHFV), Kyasanur forest disease virus (KFDV), Babesia spp, Theileria, Rickettsia conorii, Anaplasma marginale, etc. and the damages caused by them are well-recognised. There is a need to reassess the renewed threat posed by the tick vectors and to prioritize the tick control research programme. This review is focused on the major tick-borne human and animal diseases in India and the progress in vector control research with emphasis on acaricide resistance, tick vaccine and the development of potential phytoacaricides as an integral part of integrated tick control programme.

  5. Gut microbiota: A player in aging and a target for anti-aging intervention.

    PubMed

    Vaiserman, Alexander M; Koliada, Alexander K; Marotta, Francesco

    2017-05-01

    Aging-associated alterations in composition, diversity and functional features of intestinal microbiota are well-described in the modern literature. They are suggested to be caused by an age-related decline in immune system functioning (immunosenescence) and a low-grade chronic inflammation (inflammaging), which accompany many aging-associated pathologies. The microbiota-targeted dietary and probiotic interventions have been shown to favorably affect the host health and aging by an enhancement of antioxidant activity, improving immune homeostasis, suppression of chronic inflammation, regulation of fat deposition and metabolism and prevention of insulin resistance. Recently, a high effectiveness and safety of novel therapeutic application such as fecal microbiota transplantation in the prevention and treatment of age-related pathological conditions including atherosclerosis, type 2 diabetes and Parkinson's disease has been demonstrated. In this review, recent research findings are summarized on the role of gut micribiota in aging processes with emphasis on therapeutic potential of microbiome-targeted interventions in anti-aging medicine. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. PVC as pharmaceutical packaging material. A literature survey with special emphasis on plasticized PVC bags.

    PubMed

    Van Dooren, A A

    1991-06-21

    In this report the state of the art with respect to PVC as pharmaceutical packaging material is described. A general introduction into the applications of PVC is followed by a description of its production process. The metabolic effects of the monomer of PVC, vinyl chloride and of the most commonly used plasticizer diethylhexylphthalate are mentioned. Special attention is given to the pharmaceutical properties of plasticized PVC bags in comparison to other plastics and the environmental aspects of waste PVC disposal. Although there are emotional and political queries regarding the future use of PVC as a (pharmaceutical) packaging material, we conclude that there is no scientific justification for a total or partial ban of PVC. PVC will remain a fact of life as a cheap, versatile, high-performance and well-investigated plastic material for medical and pharmaceutical applications, to be replaced by newer plastics only for certain well-defined indications where the requirements of the plastic to be used are so specific that it will economically and technically be justified to use another polymer. Community and hospital pharmacists have to be prepared for a role in intake of waste plastic disposables, probably against deposit money, in order to fulfil the logistics needed for recycling.

  7. Special Concerns for Seniors: Clostridium difficile

    MedlinePlus

    ... and Drugs" Home | Contact Us Special Concerns for Seniors Clostridium difficile - an introduction Clostridium difficile (“C. diff”) ... see APUA’s contribution to CDC’s Vital Signs campaign . Seniors are especially at risk People over the age ...

  8. Bullying and Victimisation among Taiwanese Students in Special Schools

    ERIC Educational Resources Information Center

    Wei, Hsi-Sheng; Chang, Heng-Hao; Chen, Ji-Kang

    2016-01-01

    This study examined the prevalence of bullying and victimisation among students in special schools in Taiwan. The sample included 140 students with various disabilities, aged 12-18, from 10 special schools throughout Taiwan. Trained interviewers conducted face-to-face surveys using structured questionnaires. Results show that 31.8% of students in…

  9. Working with Families of Young Children with Special Needs

    ERIC Educational Resources Information Center

    McWilliam, R. A., Ed.

    2010-01-01

    This user-friendly book presents research-based best practices for serving families of children with special needs from birth to age 6. Expert contributors demonstrate how early intervention and early childhood special education can effectively address a wide range of family concerns, which in turn optimizes children's development and learning.…

  10. Mature aggressive B-cell lymphoma across age groups - molecular advances and therapeutic implications.

    PubMed

    Lange, Jonas; Lenz, Georg; Burkhardt, Birgit

    2017-02-01

    Mature B-cell lymphoma represents the most common type of Non-Hodgkin lymphoma, and different subtypes prevail at different patient ages. Areas covered: We review recent data on differences and commonalities in mature B-cell lymphoma occurring in adult and pediatric patients, with a special emphasis on molecular advances and therapeutic implications. To this end, we will discuss knowledge on diffuse large B-cell lymphoma and Burkitt lymphoma/leukemia, which are the most frequent subtypes in adult and pediatric patients, respectively, and on primary mediastinal B-cell lymphoma, which is a subtype of mature B-cell lymphoma occurring mainly in adolescents and young adults with a female predominance. Expert commentary: Molecular profiling has revealed molecular alterations that can be used to further classify the subtypes of mature B-cell lymphoma. These new subgroups frequently respond differentially to targeted therapeutic strategies. Future clinical trials utilizing new drugs will address this issue by combining clinical data and response assessment with a molecular workup of the corresponding lymphomas.

  11. Seasonal dynamics of zooplankton in Columbia–Snake River reservoirs,with special emphasis on the invasive copepod Pseudodiaptomus forbesi

    USGS Publications Warehouse

    Emerson, Joshua E.; Bollens, Stephen M.; Counihan, Timothy D.

    2015-01-01

    The Asian copepod Pseudodiaptomus forbesi has recently become established in the Columbia River. However, little is known about its ecology and effects on invaded ecosystems. We undertook a 2-year (July 2009 to June 2011) field study of the mesozooplankton in four reservoirs in the Columbia and Snake Rivers, with emphasis on the relation of the seasonal variation in distribution and abundance of P. forbesi to environmental variables. Pseudodiaptomus forbesi was abundant in three reservoirs; the zooplankton community of the fourth reservoir contained no known non-indigenous taxa. The composition and seasonal succession of zooplankton were similar in the three invaded reservoirs: a bloom of rotifers occurred in spring, native cyclopoid and cladoceran species peaked in abundance in summer, and P. forbesi was most abundant in late summer and autumn. In the uninvaded reservoir, total zooplankton abundance was very low year-round. Multivariate ordination indicated that temperature and dissolved oxygen were strongly associated with zooplankton community structure, with P. forbesi appearing to exhibit a single generation per year . The broad distribution and high abundance of P. forbesi in the Columbia–Snake River System could result in ecosystem level effects in areas intensively managed to improve conditions for salmon and other commercially and culturally important fish species. 

  12. Numerical Hydrodynamics in Special Relativity.

    PubMed

    Martí, José Maria; Müller, Ewald

    2003-01-01

    This review is concerned with a discussion of numerical methods for the solution of the equations of special relativistic hydrodynamics (SRHD). Particular emphasis is put on a comprehensive review of the application of high-resolution shock-capturing methods in SRHD. Results of a set of demanding test bench simulations obtained with different numerical SRHD methods are compared. Three applications (astrophysical jets, gamma-ray bursts and heavy ion collisions) of relativistic flows are discussed. An evaluation of various SRHD methods is presented, and future developments in SRHD are analyzed involving extension to general relativistic hydrodynamics and relativistic magneto-hydrodynamics. The review further provides FORTRAN programs to compute the exact solution of a 1D relativistic Riemann problem with zero and nonzero tangential velocities, and to simulate 1D relativistic flows in Cartesian Eulerian coordinates using the exact SRHD Riemann solver and PPM reconstruction. Supplementary material is available for this article at 10.12942/lrr-2003-7 and is accessible for authorized users.

  13. Task Training Emphasis for Determining Training Priority.

    DTIC Science & Technology

    1987-08-01

    the relative time spent on tasks performed in their current jobs. Supervisors also rated the tasks on several different task factors, including a new... different task factors, including Task Difficulty, Probable Consequences of Inadequate Performance, Task Delay Tolerance, and Recommended Training Emphasis...3 11. APPROACH. .. ..... ..... ...... ..... ..... ...... ...... 4 III. METHOD

  14. Video and Second Language Learning. Special Issue.

    ERIC Educational Resources Information Center

    Gillespie, Junetta B., Ed.

    1985-01-01

    The extent to which video has come of age with respect to language learning is the focus of this special issue, which provides information on sources of materials and offers practical ideas for the effective and creative use of those materials in second language instruction. Articles include: "Video and Language Learning: A Medium Comes of Age"…

  15. The Older Americans Act and Its Application to Native Americans. Hearing before the Special Committee on Aging. United States Senate, Ninety-Ninth Congress, Second Session (Oklahoma City, OK, June 28, 1986).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    Three panels appearing before the Senate Special Committee on Aging discuss the sensitivity of the Administration on Aging to Native Americans, coordination of services between Title II and Title VI of the Older Americans Act, and availability of services under the act. Witnesses recommend language be included in the reauthorization of the Older…

  16. 29 CFR 35.16 - Special benefits for children and the elderly.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Special benefits for children and the elderly. 35.16... Discrimination § 35.16 Special benefits for children and the elderly. If a recipient is operating a program or activity that provides special benefits to the elderly or to children, the use of such age distinctions is...

  17. 29 CFR 35.16 - Special benefits for children and the elderly.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Special benefits for children and the elderly. 35.16 Section... Discrimination § 35.16 Special benefits for children and the elderly. If a recipient is operating a program or activity that provides special benefits to the elderly or to children, the use of such age distinctions is...

  18. The education of children with special educational needs in England

    NASA Astrophysics Data System (ADS)

    Merry, Roger

    1986-03-01

    In the last few years, the Warnock Report and the 1981 Education Act have had a major effect on the education of children with special educational needs in English schools. This paper discusses the main points of the Report and the subsequent legislation and then takes examples of three local educational authorities — Leicestershire, Coventry, and Barnsley — to illustrate the range of responses that have been made. Although there is obvious overlap, the three approaches are rather different in emphasis and illustrate the ways in which an educational system based on local autonomy can respond to proposals and legislation made at national level.

  19. Early Single-Sport Specialization: A Survey of 3090 High School, Collegiate, and Professional Athletes

    PubMed Central

    Buckley, Patrick S.; Bishop, Meghan; Kane, Patrick; Ciccotti, Michael C.; Selverian, Stephen; Exume, Dominique; Emper, William; Freedman, Kevin B.; Hammoud, Sommer; Cohen, Steven B.; Ciccotti, Michael G.

    2017-01-01

    Background: Youth participation in organized sports in the United States is rising, with many athletes focusing on a single sport at an increasingly younger age. Purpose: To retrospectively compare single-sport specialization in current high school (HS), collegiate, and professional athletes with regard to the rate and age of specialization, the number of months per year of single-sport training, and the athlete’s perception of injury related to specialization. Study Design: Cross-sectional study; Level of evidence, 3. Methods: A survey was distributed to HS, collegiate, and professional athletes prior to their yearly preparticipation physical examination. Athletes were asked whether they had chosen to specialize in only 1 sport, and data were then collected pertaining to this decision. Results: A total of 3090 athletes completed the survey (503 HS, 856 collegiate, and 1731 professional athletes). A significantly greater percentage of current collegiate athletes specialized to play a single sport during their childhood/adolescence (45.2% of HS athletes, 67.7% of collegiate athletes, and 46.0% of professional athletes; P < .001). The age of single-sport specialization differed between groups and occurred at a mean age of 12.7 ± 2.4 (HS), 14.8 ± 2.5 (collegiate), and 14.1 ± 2.8 years (professional) (P < .001). Current HS (39.9%) and collegiate athletes (42.1%) recalled a statistically greater incidence of sport-related injury than current professional athletes (25.4%) (P < .001). The majority (61.7%) of professional athletes indicated that they believed specialization helps the athlete play at a higher level, compared with 79.7% of HS and 80.6% of collegiate athletes (P < .001). Notably, only 22.3% of professional athletes said they would want their own child to specialize to play only 1 sport during childhood/adolescence. Conclusion: This study provides a foundation for understanding current trends in single-sport specialization in all athletic levels. Current

  20. Special Partners: Handicapped Students and Their Peers Pair Up for Computer Tutoring.

    ERIC Educational Resources Information Center

    O'Connor, Robert T.

    1986-01-01

    The Special Partners programs at Mill Swan Communications Skill Center Magnet School brings together 16 special needs students, aged 9-17, with fifth- and sixth-grade tutors. The program results in enhanced academic skills and in the development of mutual respect between the special needs children and their partners. (GC)

  1. Professional Competencies for the Digital Age: What Library Schools Are Doing to Prepare Special Librarians

    ERIC Educational Resources Information Center

    Varlejs, Jana

    2003-01-01

    What library/information science education offerings are relevant to preparing graduates for careers in the special library sector? The strengths and weaknesses of education for special librarianship; the match between SLA's competencies statement and what is being taught in LIS master's degree programs; and the role of SLA in continuing education…

  2. 40Ar/39Ar ages of the AD 79 eruption of Vesuvius, Italy

    NASA Astrophysics Data System (ADS)

    Lanphere, Marvin; Champion, Duane; Melluso, Leone; Morra, Vincenzo; Perrotta, Annamaria; Scarpati, Claudio; Tedesco, Dario; Calvert, Andrew

    2007-01-01

    The Italian volcano, Vesuvius, erupted explosively in <Emphasis Type="SmallCaps">AD Emphasis>79. Sanidine from pumice collected at Casti Amanti in Pompeii and Villa Poppea in Oplontis yielded a weighted-mean 40Ar/39Ar age of 1925±66 years in 2004 (1σ uncertainty) from incremental-heating experiments of eight aliquants of sanidine. This is the calendar age of the eruption. Our results together with the work of Renne et al. (1997) and Renne and Min (1998) demonstrate the validity of the 40Ar/39Ar method to reconstruct the recent eruptive history of young, active volcanoes.

  3. Sodium Intake of Special Populations in the Healthy Aging in Neighborhoods of Diversity Across the Life Span (HANDLS) Study

    PubMed Central

    Cotugna, Nancy; Fanelli-Kuczmarksi, Marie; Clymer, Julie; Hotchkiss, Lawrence; Zonderman, Alan B.; Evans, Michele K.

    2013-01-01

    Objective The sodium intake of participants of the Healthy Aging in Neighborhoods of Diversity across the Life Span study who were in three of the special population groups identified by the Dietary Guidelines for Americans, 2010 (those with hypertension, African Americans, and those ≥51 years) was analyzed to determine if they met sodium recommendations. Methods The sample included 2152 African American and White subjects, aged 30-64 years. Major dietary sources of sodium for each group were determined from two 24-hour dietary recalls, and dietary intakes were compared with sodium recommendations. Dietary potassium was also evaluated. Results The intakes of the groups studied exceeded 1500 mg sodium while their potassium intakes were lower than the Adequate Intake of 4700 mg. The major contributors of sodium included “cold cuts, sausage, and franks,” “protein foods”, and yeast breads. Conclusions Excessive sodium intake characterized the diet of an urban, socioeconomically diverse population who are hypertensive or at risk for having hypertension. These findings have implications for health professionals and the food industry. PMID:23769900

  4. Potential Economic Impacts on Non-Market Cargo Allocation in U.S. Foreign Trade : with Special Analysis of the UNCTAD Code of Conduct for Liner Conferences

    DOT National Transportation Integrated Search

    1976-07-01

    The objective of the report is to analyze the impacts of the non-market allocation of cargo in the U.S.-International liner trades, with a special emphasis on analyzing the impacts of cargo allocation as prescribed by the United Nations Code of Condu...

  5. Special Education of Children with Fetal Alcohol Spectrum Disorder

    ERIC Educational Resources Information Center

    Popova, Svetlana; Lange, Shannon; Burd, Larry; Nam, Seungree; Rehm, Jürgen

    2016-01-01

    The current study aimed to estimate the cost associated with special education among children (5 to 14 years) with Fetal Alcohol Spectrum Disorder (FASD) in elementary and middle school by sex, age group, and province and territory in Canada. It was estimated that there were 6,520 students with FASD receiving special education in Canada in…

  6. Paleophysical oceanography with an emphasis on transport rates.

    PubMed

    Huybers, Peter; Wunsch, Carl

    2010-01-01

    Paleophysical oceanography is the study of the behavior of the fluid ocean of the past, with a specific emphasis on its climate implications, leading to a focus on the general circulation. Even if the circulation is not of primary concern, heavy reliance on deep-sea cores for past climate information means that knowledge of the oceanic state when the sediments were laid down is a necessity. Like the modern problem, paleoceanography depends heavily on observations, and central difficulties lie with the very limited data types and coverage that are, and perhaps ever will be, available. An approximate separation can be made into static descriptors of the circulation (e.g., its water-mass properties and volumes) and the more difficult problem of determining transport rates of mass and other properties. Determination of the circulation of the Last Glacial Maximum is used to outline some of the main challenges to progress. Apart from sampling issues, major difficulties lie with physical interpretation of the proxies, transferring core depths to an accurate timescale (the "age-model problem"), and understanding the accuracy of time-stepping oceanic or coupled-climate models when run unconstrained by observations. Despite the existence of many plausible explanatory scenarios, few features of the paleocirculation in any period are yet known with certainty.

  7. Fasting or caloric restriction for healthy aging.

    PubMed

    Anton, Stephen; Leeuwenburgh, Christiaan

    2013-10-01

    Aging is associated with a host of biological changes that contribute to a progressive decline in cognitive and physical function, ultimately leading to a loss of independence, and increased risk of mortality. To date, prolonged caloric restriction (i.e., a reduction in caloric intake without malnutrition) is the only non-genetic intervention that has consistently been found to extend both mean and maximal life span across a variety of species. Most individuals have difficulty sustaining prolonged caloric restriction, which has led to a search for alternative approaches that can produce similar to benefits as caloric restriction. A growing body of evidence indicates that fasting periods and intermittent fasting regimens in particular can trigger similar biological pathways as caloric restriction. For this reason, there is increasing scientific interest in further exploring the biological and metabolic effects of intermittent fasting periods, as well as whether long-term compliance may be improved by this type of dietary approach. This special will highlight the latest scientific findings related to the effects of both caloric restriction and intermittent fasting across various species including yeast, fruit flies, worms, rodents, primates, and humans. A specific emphasis is placed on translational research with findings from basic bench to bedside reviewed and practical clinical implications discussed. Copyright © 2013 Elsevier Inc. All rights reserved.

  8. PREFACE: Special issue: CAMOP-MOLEC XVII Special issue: CAMOP-MOLEC XVII

    NASA Astrophysics Data System (ADS)

    Vasyutinskii, Oleg

    2009-10-01

    This special issue of CAMOP/Physica Scripta presents highlights from the scientific contributions presented at the European Conference on Dynamics of Molecular Systems (MOLEC XVII) held on 23-29 August 2008 at St Petersburg, Russia. This meeting was the seventeenth in a series of biannual meetings that started in 1976, when the first conference was held in Trento, Italy. Subsequent meetings were held at Brandbjerg Hojskole (Denmark), Oxford (UK), Nijmegen (The Netherlands), Jerusalem (Israel), Aussois (France), Assisi (Italy), Bernkastel-Kues (Germany), Prague (Czech Republic), Salamanca (Spain), Nyborg Strand (Denmark), Bristol (UK), Jerusalem (Israel), Istanbul (Turkey), Nunspeet (The Netherlands) and Trento (Italy). In 2008, the meeting was jointly organized by scientists from the Ioffe Institute, Russian Academy of Sciences, St Petersburg, Herzen State University, St Petersburg, Moscow State University, St Petersburg Polytechnical University, and St Petersburg State University. About 150 scientists from 21 countries visited Pushkin, a beautiful suburb of St Petersburg near the famous palace of Empress Catherine II, and discussed the state of the art and trends in the field, as well as new methods and applications, during 24 plenary lectures, 36 hot topic talks and two evening poster sessions. A special event was the presentation of the MOLEC XVII award to Professor Grabriel Balint-Kurti for his outstanding contributions to the theory of reaction dynamics and molecular photodissociation. Further information is available from the homepage of the meeting: http://www.ioffe.ru/MOLEC17/. This special issue covers different aspects of atomic and molecular interactions, with emphasis on both experimental and theoretical studies of the dynamics of elastic, inelastic and reactive encounters between atoms, molecules, ions, clusters and surfaces. More specifically, it includes molecular collisions in different environments; plasma, atmospheric, interstellar and combustion

  9. Age Integrated Learning: A Theoretical Model.

    ERIC Educational Resources Information Center

    Heckenmueller, Jerome P.; Keller, Ann

    The concept of age integrated learning (AIL) can be derived from Erikson's theory of psychosocial development. Two emphases in his theory that are less well recognized than others are central to Erikson's theory and are the cornerstone of a rationale for AIL. The first is his emphasis on the interdependence of generations for optimal crisis…

  10. Emotions and hemispheric specialization.

    PubMed

    Kyle, N L

    1988-09-01

    Studies of lateralization and specialization of brain function have increased our understanding of emotional processes in the brain. It has been said that the way in which we understand the emotional interrelatedness of brain layers and segments may have important effects on human society. Earlier studies of brain function, especially of limbic effects, suggested a dichotomous state of affairs between the phylogenetically older brain and the newer cortical areas--between affect and cognition. Such concepts are considered here in the light of specialization studies. From the beginning hemispheric laterality research has implicated emotionality and emotional pathology. It also appears that some limbic functions may be mediated in a lateralized fashion. Neuropsychologists have directed much work toward localization of function from its earliest stage; since the 1960s an emphasis has been on "mapping" of cortical functions in terms of psychopathologic disabilities. Various disability groups have been studied in this way, and it may be concluded that neuropsychologic measures are sensitive to changes in cerebral functioning and may have effective lateralizing and localizing ability under specified conditions. Studies of limbic effects in the brain emphasize their importance in emotional behavior but also their interrelatedness with other structures, for example, the frontal and temporal lobes, and particularly the right hemisphere. Studies of commissurotomy (split-brain) patients tend to bear out these relationships. In split-brain subjects the marked reduction in affective verbal and nonverbal behavior reflects the interruption of transcallosal impulses that normally permit emotional infusion of cortical structures to take place. These effects include verbal, visual, and auditory patterns that mediate the ability to decode complex nonverbal patterns and may result in a reduction of "inner speech," that is, symbollexia. They may further lead to a condition of

  11. The Older Americans Act and the Rural Elderly. Hearing Before the Special Committee of Aging, United States Senate, Ninety-fourth Congress, First Session, April 28, 1975.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    Though amended in 1973, the Older Americans Act of 1965 has not met the needs of the rural elderly and was, consequently, the subject of these hearings by the Senate's Special Committee on Aging which consider proposed legislation under Title III of the Act to gain support for demonstration programs to assist older rural people and to improve the…

  12. Aging mechanisms in bone

    PubMed Central

    Almeida, Maria

    2012-01-01

    Advancing age and loss of bone mass and strength are closely linked. Elevated osteoblast and osteocyte apoptosis and decreased osteoblast number characterize the age-related skeletal changes in humans and rodents. Similar to other tissues, oxidative stress increases in bone with age. This article reviews current knowledge on the effects of the aging process on bone and its cellular constituents, with particular emphasis on the role of reactive oxygen species (ROS). FoxOs, sirtuins and the p53/p66shc signaling cascade alter osteoblast number and bone formation via ROS-dependent and -independent mechanisms. Specifically, activation of the p53/p66shc signaling increases osteoblast/osteocyte apoptosis in the aged skeleton and decreases bone mass. FoxO activation in osteoblasts prevents oxidative stress to preserve skeletal homeostasis. However, while defending against stress FoxOs bind to β-catenin and attenuate Wnt/T-cell cell factor transcriptional activity and osteoblast generation. Thus, pathways that impact longevity and several diseases of ageing might also contribute to age-related osteoporosis. PMID:23705067

  13. Healthy aging: The ultimate preventative medicine.

    PubMed

    Kaeberlein, Matt; Rabinovitch, Peter S; Martin, George M

    2015-12-04

    Age is the greatest risk factor for nearly every major cause of mortality in developed nations. Despite this, most biomedical research focuses on individual disease processes without much consideration for the relationships between aging and disease. Recent discoveries in the field of geroscience, which aims to explain biological mechanisms of aging, have provided insights into molecular processes that underlie biological aging and, perhaps more importantly, potential interventions to delay aging and promote healthy longevity. Here we describe some of these advances, along with efforts to move geroscience from the bench to the clinic. We also propose that greater emphasis should be placed on research into basic aging processes, because interventions that slow aging will have a greater effect on quality of life compared with disease-specific approaches. Copyright © 2015, American Association for the Advancement of Science.

  14. Self-rated health and wellbeing among school-aged children with and without special educational needs: Differences between mainstream and special schools.

    PubMed

    Rathmann, Katharina; Vockert, Theres; Bilz, Ludwig; Gebhardt, Markus; Hurrelmann, Klaus

    2018-05-11

    Studies among students with special educational needs (SEN) in separate special schools (SSS) and mainstream schools (MS) are particularly applicable to educational attainment and social participation. However, indicators of health and wellbeing have rarely been considered. This study investigates two related topics: first, health and wellbeing differences between students with SEN in special schools (SSS) and students without SEN in regular schools, and second, the rarely considered question whether health and wellbeing among students with SEN differ between school settings (i.e. MS vs. SSS). Bivariate and multilevel analyses are applied with data from the German National Educational Panel Study (NEPS) with 5267 students (grade 7). After having controlled for background characteristics, students in SSS report higher likelihoods of poor self-rated health compared to students in higher track schools. Self-rated health of students with SEN does not significantly differ between MS vs. SSS. For life satisfaction, students with SEN show higher likelihoods of low life satisfaction when attending MS. Teachers in inclusive settings are encouraged to establish class work and teaching that support a real change from class placement to inclusive culture in order to suitably support students with SEN. Copyright © 2018 Elsevier Ltd. All rights reserved.

  15. 7 CFR 3430.312 - Emphasis on sustainable agriculture.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false Emphasis on sustainable agriculture. 3430.312 Section 3430.312 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE COMPETITIVE AND NONCOMPETITIVE NON-FORMULA FEDERAL ASSISTANCE PROGRAMS-GENERAL...

  16. 7 CFR 3430.312 - Emphasis on sustainable agriculture.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false Emphasis on sustainable agriculture. 3430.312 Section 3430.312 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE COMPETITIVE AND NONCOMPETITIVE NON-FORMULA FEDERAL ASSISTANCE PROGRAMS-GENERAL...

  17. 7 CFR 3430.312 - Emphasis on sustainable agriculture.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 15 2011-01-01 2011-01-01 false Emphasis on sustainable agriculture. 3430.312 Section 3430.312 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE COMPETITIVE AND NONCOMPETITIVE NON-FORMULA FEDERAL ASSISTANCE PROGRAMS-GENERAL...

  18. 7 CFR 3430.312 - Emphasis on sustainable agriculture.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false Emphasis on sustainable agriculture. 3430.312 Section 3430.312 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE COMPETITIVE AND NONCOMPETITIVE NON-FORMULA FEDERAL ASSISTANCE PROGRAMS-GENERAL...

  19. Work after 65: Options for the 80's. Hearing before the Special Committee on Aging, United States Senate, Ninety-Sixth Congress, Second Session. Part 3--Orlando, Fla.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    The problem of senior citizens in Florida who need to work are chronicled in this third part of the Senate Special Committee on Aging, Work after 65 hearings, conducted in Orlando, Florida, in July, 1980. During the Florida hearing, representatives of various government programs for senior citizens, professors of education and economics and…

  20. Uneven-aged silviculture of longleaf pine

    Treesearch

    James M. Guldin

    2006-01-01

    The use of uneven-aged silviculture has increased markedly in the past 20 years. This is especially true in the southern United States, where the use of clearcutting and planting is often viewed as a practice whose emphasis on fiber production results in unacceptable consequences for other values, such as those that benefit from maintenance of continuous forest cover...

  1. Trophic level, successional age and trait matching determine specialization of deadwood-based interaction networks of saproxylic beetles

    PubMed Central

    Gossner, Martin M.; Grass, Ingo; Arnstadt, Tobias; Hofrichter, Martin; Floren, Andreas; Linsenmair, Karl Eduard; Weisser, Wolfgang W.; Steffan-Dewenter, Ingolf

    2017-01-01

    The specialization of ecological networks provides important insights into possible consequences of biodiversity loss for ecosystem functioning. However, mostly mutualistic and antagonistic interactions of living organisms have been studied, whereas detritivore networks and their successional changes are largely unexplored. We studied the interactions of saproxylic (deadwood-dependent) beetles with their dead host trees. In a large-scale experiment, 764 logs of 13 tree species were exposed to analyse network structure of three trophic groups of saproxylic beetles over 3 successional years. We found remarkably high specialization of deadwood-feeding xylophages and lower specialization of fungivorous and predatory species. During deadwood succession, community composition, network specialization and network robustness changed differently for the functional groups. To reveal potential drivers of network specialization, we linked species' functional traits to their network roles, and tested for trait matching between plant (i.e. chemical compounds) and beetle (i.e. body size) traits. We found that both plant and animal traits are major drivers of species specialization, and that trait matching can be more important in explaining interactions than neutral processes reflecting species abundance distributions. High network specialization in the early successional stage and decreasing network robustness during succession indicate vulnerability of detritivore networks to reduced tree species diversity and beetle extinctions, with unknown consequences for wood decomposition and nutrient cycling. PMID:28469020

  2. Special Education of Children with Fetal Alcohol Spectrum Disorder

    PubMed Central

    Popova, Svetlana; Lange, Shannon; Burd, Larry; Nam, Seungree; Rehm, Jürgen

    2016-01-01

    Abstract The current study aimed to estimate the cost associated with special education among children (5 to 14 years) with Fetal Alcohol Spectrum Disorder (FASD) in elementary and middle school by sex, age group, and province and territory in Canada. It was estimated that there were 6,520 students with FASD receiving special education in Canada in 2011–2012. The cost of special education among these students was 53.5 million Canadian dollars. Implications for decision- and policymakers, educational systems and school staff are discussed. PMID:27695197

  3. Cryptic etiopathological conditions of equine nervous system with special emphasis on viral diseases

    PubMed Central

    Kumar, Rakesh; Patil, Rajendra D.

    2017-01-01

    The importance of horse (Equus caballus) to equine practitioners and researchers cannot be ignored. An unevenly distributed population of equids harbors numerous diseases, which can affect horses of any age and breed. Among these, the affections of nervous system are potent reason for death and euthanasia in equids. Many episodes associated with the emergence of equine encephalitic conditions have also pose a threat to human population as well, which signifies their pathogenic zoonotic potential. Intensification of most of the arboviruses is associated with sophisticated interaction between vectors and hosts, which supports their transmission. The alphaviruses, bunyaviruses, and flaviviruses are the major implicated groups of viruses involved with equines/humans epizootic/epidemic. In recent years, many outbreaks of deadly zoonotic diseases such as Nipah virus, Hendra virus, and Japanese encephalitis in many parts of the globe addresses their alarming significance. The equine encephalitic viruses differ in their global distribution, transmission and main vector species involved, as discussed in this article. The current review summarizes the status, pathogenesis, pathology, and impact of equine neuro-invasive conditions of viral origin. A greater understanding of these aspects might be able to provide development of advances in neuro-protective strategies in equine population. PMID:29391683

  4. Special Problems of the Elderly.

    ERIC Educational Resources Information Center

    Hull, Kathleen V.

    Within the next 40 years, people age 65 and over will comprise 20% of the population, yet problems facing this older generation and their families are just coming to the attention of researchers and the public. Accordingly, this literature review focuses on the special needs of older adults and their families. After an introductory overview, the…

  5. 20 CFR 404.1058 - Special situations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Employment, Wages, Self-Employment, and Self-Employment Income Wages § 404.1058 Special situations. (a... as a home worker in a common-law employment relationship (see § 404.1007) count as wages regardless...

  6. 20 CFR 404.1058 - Special situations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Employment, Wages, Self-Employment, and Self-Employment Income Wages § 404.1058 Special situations. (a... as a home worker in a common-law employment relationship (see § 404.1007) count as wages regardless...

  7. 20 CFR 404.1058 - Special situations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Employment, Wages, Self-Employment, and Self-Employment Income Wages § 404.1058 Special situations. (a... as a home worker in a common-law employment relationship (see § 404.1007) count as wages regardless...

  8. 20 CFR 404.1058 - Special situations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Employment, Wages, Self-Employment, and Self-Employment Income Wages § 404.1058 Special situations. (a... as a home worker in a common-law employment relationship (see § 404.1007) count as wages regardless...

  9. 75 FR 11187 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... for Scientific Review Special Emphasis Panel; Epidemiology of Diseases of Aging. Date: March 31, 2010... Conflicts: Cell Biology. Date: April 13-14, 2010. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate...

  10. LEARNING AND CREATIVITY WITH SPECIAL EMPHASIS ON SCIENCE.

    ERIC Educational Resources Information Center

    SULLIVAN, JOHN J.; TAYLOR, CALVIN W.

    PAPERS CONCERNING (1) LEARNING AND METHODS OF INVESTIGATION, AND (2) CREATIVITY AND PRODUCTIVE THINKING ARE INCLUDED IN THIS NATIONAL SCIENCE TEACHERS ASSOCIATION PUBLICATION. IN THE PAPER THAT DEALS WITH LEARNING, A DEFINITION OF LEARNING AND A DESCRIPTION OF BEHAVIORAL PSYCHOLOGY ARE FOLLOWED BY A DISCUSSION OF DISCRIMINATIVE STIMULI AND…

  11. Sports specialization in young athletes: evidence-based recommendations.

    PubMed

    Jayanthi, Neeru; Pinkham, Courtney; Dugas, Lara; Patrick, Brittany; Labella, Cynthia

    2013-05-01

    Sports specialization is intense training in 1 sport while excluding others. Sports specialization in early to middle childhood has become increasingly common. While most experts agree that some degree of sports specialization is necessary to achieve elite levels, there is some debate as to whether such intense practice time must begin during early childhood and to the exclusion of other sports to maximize potential for success. There is a concern that sports specialization before adolescence may be deleterious to a young athlete. PubMed and OVID were searched for English-language articles from 1990 to 2011 discussing sports specialization, expert athletes, or elite versus novice athletes, including original research articles, consensus opinions, and position statements. For most sports, there is no evidence that intense training and specialization before puberty are necessary to achieve elite status. Risks of early sports specialization include higher rates of injury, increased psychological stress, and quitting sports at a young age. Sports specialization occurs along a continuum. Survey tools are being developed to identify where athletes fall along the spectrum of specialization. Some degree of sports specialization is necessary to develop elite-level skill development. However, for most sports, such intense training in a single sport to the exclusion of others should be delayed until late adolescence to optimize success while minimizing injury, psychological stress, and burnout.

  12. Special Education Placement and the Self-Concepts of Elementary-School Age Children.

    ERIC Educational Resources Information Center

    Yauman, Beth E.

    1980-01-01

    The study investigated the relatonship between degree or extent of special education participation and measured self-concept with 45 third-grade male students divided into three groups (students in self-contained LD classes, students provided individual tutoring, and a control group of students from regular classes). (Author/PHR)

  13. Phytoplankton dynamics with a special emphasis on harmful algal blooms in the Mar Piccolo of Taranto (Ionian Sea, Italy).

    PubMed

    Caroppo, Carmela; Cerino, Federica; Auriemma, Rocco; Cibic, Tamara

    2016-07-01

    The response of phytoplankton assemblages to the closure of urban sewage outfalls (USOs) was examined for the Mar Piccolo of Taranto (Mediterranean Sea), a productive semi-enclosed coastal marine ecosystem devoted to shellfish farming. Phytoplankton dynamics were investigated in relation to environmental variables, with a particular emphasis on harmful algal blooms (HABs). Recent analyses evidenced a general reduction of the inorganic nutrient loads, except for nitrates and silicates. Also phytoplankton biomass (chlorophyll a) and abundances were characterized by a decrease of the values, except for the inner area of the basin (second inlet). The phytoplankton composition changed, with nano-sized species, indicators of oligotrophic conditions, becoming dominant over micro-sized species. If the closure of the USOs affected phytoplankton dynamics, however, it did not preserve the Mar Piccolo from HABs and anoxia crises. About 25 harmful species have been detected throughout the years, such as the potentially domoic acid producers Pseudo-nitzschia cf. galaxiae and P seudo-nitzschia cf. multistriata, identified for the first time in these waters. The presence of HABs represents a threat for human health and aquaculture. Urgent initiatives are needed to improve the communication with authorities responsible for environmental protection, economic development, and public health for a sustainable mussel culture in the Mar Piccolo.

  14. Incarceration Recidivism in the Adolescent Special Education Population: Perceptions and Challenges

    ERIC Educational Resources Information Center

    Shepherd, Tina D.

    2013-01-01

    In 1990, The Americans with Disabilities Act ruled that, regardless of age, inmates were entitled to continued special education services in correctional facilities. This qualitative case study identified perceptions of recidivism in incarcerated adolescents with special education needs. In this study the correctional education programs were…

  15. 20 CFR 416.265 - Requirements for the special SSI eligibility status.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Requirements for the special SSI eligibility status. 416.265 Section 416.265 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

  16. 20 CFR 416.262 - Eligibility requirements for special SSI cash benefits.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Eligibility requirements for special SSI cash benefits. 416.262 Section 416.262 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

  17. 20 CFR 416.265 - Requirements for the special SSI eligibility status.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Requirements for the special SSI eligibility status. 416.265 Section 416.265 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

  18. 20 CFR 416.265 - Requirements for the special SSI eligibility status.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Requirements for the special SSI eligibility status. 416.265 Section 416.265 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

  19. 20 CFR 416.262 - Eligibility requirements for special SSI cash benefits.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Eligibility requirements for special SSI cash benefits. 416.262 Section 416.262 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

  20. 20 CFR 416.262 - Eligibility requirements for special SSI cash benefits.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Eligibility requirements for special SSI cash benefits. 416.262 Section 416.262 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

  1. Special considerations in paediatric burn patients

    PubMed Central

    Sharma, Ramesh Kumar; Parashar, Atul

    2010-01-01

    Burn injuries are a major cause of morbidity and mortality in children. In India, the figure constitutes about one-fourth of the total burn accidents. The management of paediatric burns can be a major challenge for the treating unit. One has to keep in mind that “children are not merely small adults”; there are certain features in this age group that warrant special attention. The peculiarities in the physiology of fluid and electrolyte handling, the uniqueness of the energy requirement and the differences in the various body proportions in children dictate that the paediatric burn management should be taken with a different perspective than for adults. This review article would deal with the special situations that need to be addressed while treating this special class of thermal injuries. We must ensure that not only the children survive the initial injury, but also the morbidity and complications are minimized. If special care is taken during the initial management of paediatric burn injuries, these children can be effectively integrated into the society as very useful and productive members. PMID:21321657

  2. Central role for NMDA receptors in redox mediated impairment of synaptic function during aging and Alzheimer's disease.

    PubMed

    Foster, T C; Kyritsopoulos, C; Kumar, A

    2017-03-30

    Increased human longevity has magnified the negative impact that aging can have on cognitive integrity of older individuals experiencing some decline in cognitive function. Approximately 30% of the elderly will have cognitive problems that influence their independence. Impaired executive function and memory performance are observed in normal aging and yet can be an early sign of a progressive cognitive impairment of Alzheimer's disease (AD), the most common form of dementia. Brain regions that are vulnerable to aging exhibit the earliest pathology of AD. Senescent synaptic function is observed as a shift in Ca 2+ -dependent synaptic plasticity and similar mechanisms are thought to contribute to the early cognitive deficits associated with AD. In the case of aging, intracellular redox state mediates a shift in Ca 2+ regulation including N-methyl-d-aspartate (NMDA) receptor hypofunction and increased Ca 2+ release from intracellular stores to alter synaptic plasticity. AD can interact with these aging processes such that molecules linked to AD, β-amyloid (Aβ) and mutated presenilin 1 (PS1), can also degrade NMDA receptor function, promote Ca 2+ release from intracellular stores, and may increase oxidative stress. Thus, age is one of the most important predictors of AD and brain aging likely contributes to the onset of AD. The focus of this review article is to provide an update on mechanisms that contribute to the senescent synapse and possible interactions with AD-related molecules, with special emphasis on regulation of NMDA receptors. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases

    PubMed Central

    Davalli, Pierpaola; Mitic, Tijana; Caporali, Andrea; Lauriola, Angela; D'Arca, Domenico

    2016-01-01

    The aging process worsens the human body functions at multiple levels, thus causing its gradual decrease to resist stress, damage, and disease. Besides changes in gene expression and metabolic control, the aging rate has been associated with the production of high levels of Reactive Oxygen Species (ROS) and/or Reactive Nitrosative Species (RNS). Specific increases of ROS level have been demonstrated as potentially critical for induction and maintenance of cell senescence process. Causal connection between ROS, aging, age-related pathologies, and cell senescence is studied intensely. Senescent cells have been proposed as a target for interventions to delay the aging and its related diseases or to improve the diseases treatment. Therapeutic interventions towards senescent cells might allow restoring the health and curing the diseases that share basal processes, rather than curing each disease in separate and symptomatic way. Here, we review observations on ROS ability of inducing cell senescence through novel mechanisms that underpin aging processes. Particular emphasis is addressed to the novel mechanisms of ROS involvement in epigenetic regulation of cell senescence and aging, with the aim to individuate specific pathways, which might promote healthy lifespan and improve aging. PMID:27247702

  4. Special Education Forms. Volume 1: School-Age Students.

    ERIC Educational Resources Information Center

    Fink, Sandra; And Others

    This document comprises forms (and directions for their use) used in Oregon in conjunction with the Individuals with Disabilities Education Act (IDEA) for school-aged children. Forms are identified as either required or optional and are presented in a two-page format, with one page identifying the form, explaining its purposes, and providing…

  5. [Keratoconus special soft contact lens fitting].

    PubMed

    Yamazaki, Ester Sakae; da Silva, Vanessa Cristina Batista; Morimitsu, Vagner; Sobrinho, Marcelo; Fukushima, Nelson; Lipener, César

    2006-01-01

    To evaluate the fitting and use of a soft contact lens in keratoconic patients. Retrospective study on 80 eyes of 66 patients, fitted with a special soft contact lens for keratoconus, at the Contact Lens Section of UNIFESP and private clinics. Keratoconus was classified according to degrees of disease severity by keratometric pattern. Age, gender, diagnosis, keratometry, visual acuity, spherical equivalent (SE), base curve and clinical indication were recorded. Of 66 patients (80 eyes) with keratoconus the mean age was 29 years, 51.5% were men and 48.5% women. According to the groups: 15.0% were incipient, 53.7% moderate, 26.3% advanced and 5.0% were severe. The majority of the eyes of patients using contact lenses (91.25%) achieved visual acuity better than 20/40. To 88 eyes 58% were tihed with lens with spherical power (mean -5.45 diopters) and 41% with spherocylinder power (from -0.5 to -5.00 cylindrical diopters). The most frequent base curve was 7.6 in 61% of the eyes. The main reasons for this special lens fitting were due to reduced tolerance and poor fitting pattern achieved with other lenses. The special soft contact lens is useful in fitting difficult keratoconic patients by offering comfort and improving visual rehabilitation that may allow more patients to postpone the need for corneal transplant.

  6. 76 FR 64359 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ... Brain, Neurotransmission and Aging Special Emphasis Panel. Date: November 1, 2011. Time: 8 a.m. to 5 p.m...: Cell, Computational and Molecular Biology. Date: November 9, 2011. Time: 10 a.m. to 6 p.m. Agenda: To...

  7. Special Issue: "Getting of Wisdom", Learning in Later Life

    ERIC Educational Resources Information Center

    Krašovec, Sabina Jelenc; Golding, Barry; Findsen, Brian; Schmidt-Hertha, Bernhard

    2017-01-01

    This specially themed ""Getting of Wisdom," Learning in Later Life" Edition of the "Australian Journal of Adult Learning" ("AJAL") is not so much concerned with the issue of ageing itself, but more about quality of life regardless of age. It is about taking, but also giving back as best as possible at any…

  8. Our Greatest Generation: Continuing a Lifetime of Service. Hearing before the Special Committee on Aging. United States Senate, One Hundred Seventh Congress, First Session (Indianapolis, Indiana, August 9, 2001).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    This Congressional report contains the remarks made at a special meeting of the United States Committee on Aging to celebrate senior citizen's service to their community and examine policies regarding federally funded senior service programs. The following are among the programs, agencies, and organizations represented: Senior Companion Program;…

  9. 34 CFR 110.16 - Special benefits for children and the elderly.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Special benefits for children and the elderly. 110.16 Section 110.16 Education Regulations of the Offices of the Department of Education OFFICE FOR CIVIL RIGHTS... FINANCIAL ASSISTANCE Standards for Determining Age Discrimination § 110.16 Special benefits for children and...

  10. 20 CFR 416.262 - Eligibility requirements for special SSI cash benefits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Eligibility requirements for special SSI cash benefits. 416.262 Section 416.262 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A Disabling Impairment § 416.262...

  11. Predictors of low back pain in physically active conscripts with special emphasis on muscular fitness.

    PubMed

    Taanila, Henri P; Suni, Jaana H; Pihlajamäki, Harri K; Mattila, Ville M; Ohrankämmen, Olli; Vuorinen, Petteri; Parkkari, Jari P

    2012-09-01

    Association between low physical fitness and low back pain (LBP) is contradictory in previous studies. The objective of the present prospective cohort study was to investigate the predictive associations of various intrinsic risk factors in young conscripts for LBP, with special attention to physical fitness. A prospective cohort study. A representative sample of Finnish male conscripts. In Finland, military service is compulsory for male citizens and 90% of young men enter into the service. Incidence of LBP and recurrent LBP prompting a visit at the garrison health clinic during 6-month military training. Four successive cohorts of 18- to 28-year-old male conscripts (N=982) were followed for 6 months. Conscripts with incidence of LBP were identified and treated at the garrison clinic. Predictive associations between intrinsic risk factors and LBP were examined using multivariate Cox proportional hazard models. The cumulative incidence of LBP was 16%, the incidence rate being 1.2 (95% confidence interval [CI], 1.0-1.4) per 1,000 person-days. Conscripts with low educational level had increased risk for incidence of LBP (hazard ratio [HR], 1.6; 95% CI, 1.1-2.3). Conscripts with low dynamic trunk muscle endurance and low aerobic endurance simultaneously (ie, having coimpairment) at baseline also had an increased risk for incidence of LBP. The strongest risk factor was coimpairment of trunk muscular endurance in tests of back lift and push-up (HR, 2.8; 95% CI, 1.4-5.9). The increased risk for LBP was observed among young men who had a low educational level and poor fitness level in both muscular and aerobic performance. Copyright © 2012 Elsevier Inc. All rights reserved.

  12. Paradoxical Trend for Improvement in Mental Health With Aging: A Community-Based Study of 1,546 Adults Aged 21-100 Years.

    PubMed

    Thomas, Michael L; Kaufmann, Christopher N; Palmer, Barton W; Depp, Colin A; Martin, Averria Sirkin; Glorioso, Danielle K; Thompson, Wesley K; Jeste, Dilip V

    2016-08-01

    Studies of aging usually focus on trajectories of physical and cognitive function, with far less emphasis on overall mental health, despite its impact on general health and mortality. This study examined linear and nonlinear trends of physical, cognitive, and mental health over the entire adult lifespan. Cross-sectional data were obtained from 1,546 individuals aged 21-100 years, selected using random digit dialing for the Successful AGing Evaluation (SAGE) study, a structured multicohort investigation that included telephone interviews and in-home surveys of community-based adults without dementia. Data were collected from 1/26/2010 to 10/07/2011 targeting participants aged 50-100 years and from 6/25/2012 to 7/15/2013 targeting participants aged 21-100 years with an emphasis on adding younger individuals. Data included self-report measures of physical health, measures of both positive and negative attributes of mental health, and a phone interview-based measure of cognition. Comparison of age cohorts using polynomial regression suggested a possible accelerated deterioration in physical and cognitive functioning, averaging 1.5 to 2 standard deviations over the adult lifespan. In contrast, there appeared to be a linear improvement of about 1 standard deviation in various attributes of mental health over the same life period. These cross-sectional findings suggest the possibility of a linear improvement in mental health beginning in young adulthood rather than a U-shaped curve reported in some prior studies. Lifespan research combining psychosocial and biological markers may improve our understanding of resilience to mental disability in older age and lead to broad-based interventions promoting mental health in all age groups. © Copyright 2016 Physicians Postgraduate Press, Inc.

  13. [Declining fertility with age].

    PubMed

    Lourdel, Emmanuelle; Merviel, Philippe; Cabry-Goubet, Rosalie; Brzakowski, Mélanie

    2010-06-20

    The will to be a mother at a late age has become a real problem of society for many reasons, first and foremost because of efficient birth control, long studies and second matrimonies. In front of these still young women but quite "old" for maternity, practitioners specialized in medically assisted procreation (MAP) are often helpless, specially because most of the patients think that the MAP will be able to cure the natural decline of fertility. However, MAP's procedures cannot correct the decrease of pregnancies' rates and the increase of spontaneous miscarriages linked with the age. One of the first aims of consulting-physicians should be to give patients proper advice about fertility decline, so that women could run their life, aware of these facts.

  14. The Neurotoxicity of General Anesthetic Drugs: Emphasis on the Extremes of Age.

    PubMed

    Biddle, Chuck; Ford, Vincent

    2017-01-01

    A substantial body of research suggests that anesthetic exposure to patients who are very young or very old may impair cognitive, behavioral, and emotional development or recovery. In lower animal models of pre- and postnatal age, anesthetic exposure may impact inflammation, synaptogenesis, neuronal apoptosis, and glial cell development. To date, research in humans is inconclusive regarding the long-term cognitive and behavioral sequelae of general anesthesia in the young child. In older adults, postoperative cognitive dysfunction and cognitive delirium are identified as markers of anesthetic neurotoxicity. Existing neurological degenerative processes and other comorbidities in combination with the stress of surgery make evaluating the independent impact of anesthetic exposure difficult. Advances in research, imaging, and partnerships have enhanced the potential for understanding the impact of anesthetic exposure. In both populations, the resulting data and limitations faced in initial research efforts are catalysts for current prospective studies.

  15. Emphasis: Five Ways to Cure Boring Student Writing.

    ERIC Educational Resources Information Center

    Foster, Mary Ellen

    A careful use of emphasis by students in their writing can be promoted by some exercises assigned by composition teachers. A drawing exercise can help students learn that changing the length of sentences makes paragraphs more interesting. Using Elizabeth Kubler-Ross's five categories of grief to consider times of depression in students' lives…

  16. Northern Suburban Special Recreation Association (NSSRA).

    ERIC Educational Resources Information Center

    Northern Suburban Special Recreation Association, Highland Park, IL.

    This document is a description of the Northern Suburban Special Recreation Association (NSSRA) whose function is to provide recreation for the handicapped, primarily school-aged children. Recreation is defined as not just diversion but the restoration of strength and spirits after toil. It is stated that the NSSRA's programs are grouped to…

  17. Shakespeare on old age and disability.

    PubMed

    Covey, H

    2000-01-01

    The plays of William Shakespeare were reviewed for references to disabilities, aging and disability, and older characters with disabilities. Shakespeare's references draw from traditional cultural notions about older people with disabilities. These traditional notions include people with physical disabilities being evil, the entertainment value of disabilty, and those who were mentally ill being wild and animal-like. He viewed the aging process as disabling and old age as a time when individuals lost some abilities to function, particularly when it came to mental capacity and physical mobility. His writings show that he used disability as a literary tool to add dimension to characters and set them apart. Contemporary literature continues to share some of Shakespeare's view on aging and disability but also departs from them in important ways. For example, contemporary treatment of disabilities and aging places more emphasis on the human side of the affects of aging and disabilities. Disabilities and aging are not cast in the same negative terms as Shakespeare used.

  18. Pro-B selection method for uneven-aged management of longleaf pine forests

    Treesearch

    Dale G. Brockway; Edward F. Loewenstein; Kenneth W. Outcalt

    2015-01-01

    Interest in uneven-aged silviculture has increased since advent of ecosystem management programs, which place greater emphasis on ecological values and ecosystem services while also harvesting timber from the forest. However, traditional uneven-aged approaches (e.g., BDq) are often criticized as too complex, costly, and requiring highly-trained staff. The Proportional-...

  19. 20 CFR 416.265 - Requirements for the special SSI eligibility status.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Requirements for the special SSI eligibility status. 416.265 Section 416.265 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A Disabling Impairment § 416.265 Requirement...

  20. Academic attainment and special educational needs in extremely preterm children at 11 years of age: the EPICure study.

    PubMed

    Johnson, S; Hennessy, E; Smith, R; Trikic, R; Wolke, D; Marlow, N

    2009-07-01

    To assess academic attainment and special educational needs (SEN) in extremely preterm children in middle childhood. Of 307 extremely preterm (< or =25 weeks) survivors born in the UK and Ireland in 1995, 219 (71%) were re-assessed at 11 years of age and compared to 153 classmates born at term, using standardised tests of cognitive ability and academic attainment and teacher reports of school performance and SEN. Multiple imputation was used to correct for selective dropout. Extremely preterm children had significantly lower scores than classmates for cognitive ability (-20 points; 95% CI -23 to -17), reading (-18 points; -22 to -15) and mathematics (-27 points; -31 to -23). Twenty nine (13%) extremely preterm children attended special school. In mainstream schools, 105 (57%) extremely preterm children had SEN (OR 10; 6 to 18) and 103 (55%) required SEN resource provision (OR 10; 6 to 18). Teachers rated 50% of extremely preterm children as having below average attainment compared with 5% of classmates (OR 18; 8 to 41). Extremely preterm children who entered compulsory education an academic year early due to preterm birth had similar academic attainment but required more SEN support (OR 2; 1.0 to 3.6). Extremely preterm survivors remain at high risk for learning impairments and poor academic attainment in middle childhood. A significant proportion require full-time specialist education and over half of those attending mainstream schools require additional health or educational resources to access the national curriculum. The prevalence and impact of SEN are likely to increase as these children approach the transition to secondary school.

  1. Improving Legal Representation for Older Americans. Hearing Before the Special Committee on Aging, United States Senate, Ninety-Fourth Congress, Second Session. Part 2--Boston, Mass., August 30, 1976.

    ERIC Educational Resources Information Center

    1977

    The minutes of the meeting of the Special Committee on Aging of the U.S. Senate on the issue of legal services programs for the elderly, specifically programs in effect in the Boston area include statements made by the following: (1) an elderly diabetic woman testifying about living conditions and lack of services in her housing project; (2) the…

  2. 20 CFR 416.264 - When does the special SSI eligibility status apply.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false When does the special SSI eligibility status apply. 416.264 Section 416.264 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

  3. A Practical Guide to Early Numeracy Instruction for General and Special Educators

    ERIC Educational Resources Information Center

    Anderson, Alida

    2013-01-01

    This report summarizes recommendations from NCTM, NRC, CCSSM, NMAP, and IES to guide early numeracy instruction for elementary age students in general and special education classroom settings. We highlight common threads among general and special education research recommendations and provide a numeracy intervention curriculum model connecting…

  4. 20 CFR 416.264 - When does the special SSI eligibility status apply.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false When does the special SSI eligibility status apply. 416.264 Section 416.264 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

  5. 20 CFR 416.264 - When does the special SSI eligibility status apply.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false When does the special SSI eligibility status apply. 416.264 Section 416.264 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

  6. 20 CFR 416.264 - When does the special SSI eligibility status apply.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false When does the special SSI eligibility status apply. 416.264 Section 416.264 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

  7. The adverse health effects of synthetic cannabinoids with emphasis on psychosis-like effects.

    PubMed

    van Amsterdam, Jan; Brunt, Tibor; van den Brink, Wim

    2015-03-01

    Cannabis use is associated with an increased risk of psychosis in vulnerable individuals. Cannabis containing high levels of the partial cannabinoid receptor subtype 1 (CB1) agonist tetrahydrocannabinol (THC) is associated with the induction of psychosis in susceptible subjects and with the development of schizophrenia, whereas the use of cannabis variants with relatively high levels of cannabidiol (CBD) is associated with fewer psychotic experiences. Synthetic cannabinoid receptor agonists (SCRAs) are full agonists and often more potent than THC. Moreover, in contrast to natural cannabis, SCRAs preparations contain no CBD so that these drugs may have a higher psychosis-inducing potential than cannabis. This paper reviews the general toxicity profile and the adverse effects of SCRAs with special emphasis on their psychosis-inducing risk. The review shows that, compared with the use of natural cannabis, the use of SCRAs may cause more frequent and more severe unwanted negative effects, especially in younger, inexperienced users. Psychosis and psychosis-like conditions seem to occur relatively often following the use of SCRAs, presumably due to their high potency and the absence of CBD in the preparations. Studies on the relative risk of SCRAs compared with natural cannabis to induce or evoke psychosis are urgently needed. © The Author(s) 2015.

  8. Stochastic Modulations of the Pace and Patterns of Ageing: Impacts on Quasi-Stochastic Distributions of Multiple Geriatric Pathologies

    PubMed Central

    Martin, George M.

    2011-01-01

    All phenotypes result from interactions between Nature, Nurture and Chance. The constitutional genome is clearly the dominant factor in explaining the striking differences in the pace and patterns of ageing among species. We are now in a position to reveal salient features underlying these differential modulations, which are likely to be dominated by regulatory domains. By contrast, I shall argue that stochastic events are the major players underlying the surprisingly large intra-specific variations in lifespan and healthspan. I shall review well established as well as more speculative categories of chance events – somatic mutations, protein synthesis error catastrophe and variegations of gene expression (epigenetic drift), with special emphasis upon the latter. I shall argue that stochastic drifts in variegated gene expression are the major contributors to intra-specific differences in the pace and patterns of ageing within members of the same species. They may be responsible for the quasi-stochastic distributions of major types of geriatric pathologies, including the “big three” of Alzheimer's disease, atherosclerosis and, via the induction of hyperplasis, cancer. They may be responsible for altered stoichiometries of heteromultimeric mitochondrial complexes, potentially leading to such disorders as sarcopenia, nonischemic cardiomyopathy and Parkinson's disease. PMID:21963385

  9. Microphone directionality, pre-emphasis filter, and wind noise in cochlear implants.

    PubMed

    Chung, King; McKibben, Nicholas

    2011-10-01

    Wind noise can be a nuisance or a debilitating masker for cochlear implant users in outdoor environments. Previous studies indicated that wind noise at the microphone/hearing aid output had high levels of low-frequency energy and the amount of noise generated is related to the microphone directionality. Currently, cochlear implants only offer either directional microphones or omnidirectional microphones for users at-large. As all cochlear implants utilize pre-emphasis filters to reduce low-frequency energy before the signal is encoded, effective wind noise reduction algorithms for hearing aids might not be applicable for cochlear implants. The purposes of this study were to investigate the effect of microphone directionality on speech recognition and perceived sound quality of cochlear implant users in wind noise and to derive effective wind noise reduction strategies for cochlear implants. A repeated-measure design was used to examine the effects of spectral and temporal masking created by wind noise recorded through directional and omnidirectional microphones and the effects of pre-emphasis filters on cochlear implant performance. A digital hearing aid was programmed to have linear amplification and relatively flat in-situ frequency responses for the directional and omnidirectional modes. The hearing aid output was then recorded from 0 to 360° at flow velocities of 4.5 and 13.5 m/sec in a quiet wind tunnel. Sixteen postlingually deafened adult cochlear implant listeners who reported to be able to communicate on the phone with friends and family without text messages participated in the study. Cochlear implant users listened to speech in wind noise recorded at locations that the directional and omnidirectional microphones yielded the lowest noise levels. Cochlear implant listeners repeated the sentences and rated the sound quality of the testing materials. Spectral and temporal characteristics of flow noise, as well as speech and/or noise characteristics before

  10. Sports Specialization, Part II

    PubMed Central

    Myer, Gregory D.; Jayanthi, Neeru; DiFiori, John P.; Faigenbaum, Avery D.; Kiefer, Adam W.; Logerstedt, David; Micheli, Lyle J.

    2016-01-01

    Context: Many coaches, parents, and children believe that the best way to develop elite athletes is for them to participate in only 1 sport from an early age and to play it year-round. However, emerging evidence to the contrary indicates that efforts to specialize in 1 sport may reduce opportunities for all children to participate in a diverse year-round sports season and can lead to lost development of lifetime sports skills. Early sports specialization may also reduce motor skill development and ongoing participation in games and sports as a lifestyle choice. The purpose of this review is to employ the current literature to provide evidence-based alternative strategies that may help to optimize opportunities for all aspiring young athletes to maximize their health, fitness, and sports performance. Evidence Acquisition: Nonsystematic review with critical appraisal of existing literature. Study Design: Clinical review. Level of Evidence: Level 4. Conclusion: Based on the current evidence, parents and educators should help provide opportunities for free unstructured play to improve motor skill development and youth should be encouraged to participate in a variety of sports during their growing years to influence the development of diverse motor skills. For those children who do choose to specialize in a single sport, periods of intense training and specialized sport activities should be closely monitored for indicators of burnout, overuse injury, or potential decrements in performance due to overtraining. Last, the evidence indicates that all youth should be involved in periodized strength and conditioning (eg, integrative neuromuscular training) to help them prepare for the demands of competitive sport participation, and youth who specialize in a single sport should plan periods of isolated and focused integrative neuromuscular training to enhance diverse motor skill development and reduce injury risk factors. Strength of Recommendation Taxonomy (SORT): B. PMID

  11. Intellectual property considerations for molecular diagnostic development with emphasis on companion diagnostics.

    PubMed

    Glorikian, Harry; Warburg, Richard Jeremy; Moore, Kelly; Malinowski, Jennifer

    2018-02-01

    The development of molecular diagnostics is a complex endeavor, with multiple regulatory pathways to consider and numerous approaches to development and commercialization. Companion diagnostics, devices which are "essential for the safe and effective use of a corresponding drug or diagnostic product" (see U.S. Food & Drug Administration, In Vitro Diagnostics - Companion Diagnostics, U.S. Dept. of Health & Human Services(2016), available at https://www.fda.gov/medicaldevices/productsandmedicalprocedures/invitrodiagnostics/ucm407297.htm ) and complementary diagnostics, which are more broadly associated with a class of drug, are becoming increasingly important as integral components of the implementation of precision medicine. Areas covered: The following article will highlight the intellectual property ('IP') considerations pertinent to molecular diagnostics development with special emphasis on companion diagnostics. Expert opinion/commentary Summary: For all molecular diagnostics, intellectual property (IP) concerns are of paramount concern, whether the device will be marketed only in the United States or abroad. Taking steps to protect IP at each stage of product development is critical to optimize profitability of a diagnostic product. Also the legal framework around IP protection of diagnostic technologies has been changing over the previous few years and can be expected to continue to change in the foreseeable near future, thus, a comprehensive IP strategy should take into account the fact that changes in the law can be expected.

  12. Special Education Services Received by Students with Autism Spectrum Disorders from Preschool through High School

    PubMed Central

    Wei, Xin; Wagner, Mary; Christiano, Elizabeth R.A.; Shattuck, Paul; Yu, Jennifer W.

    2014-01-01

    Little is known about how special education services received by students with Autism Spectrum Disorders (ASDs) differ by age, disability severity, and demographic characteristics. Using three national datasets, the Pre-Elementary Education Longitudinal Study (PEELS), the Special Education Elementary Longitudinal Study (SEELS), and the National Longitudinal Transition Study-2 (NLTS2), this study examined the age trends in special education services received by students with ASDs from preschool through high school. Elementary-school students with ASDs had higher odds of receiving adaptive physical education, specialized computer software or hardware, and special transportation, but lower odds of receiving learning strategies/study skills support than their preschool peers. Secondary-school students had lower odds of receiving speech/language or occupational therapy and of having a behavior management program, but higher odds of receiving mental health or social work services than their elementary-school peers. Both disability severity and demographic characteristics were associated with differences in special education service receipt rates. PMID:25419002

  13. Special Education Services Received by Students with Autism Spectrum Disorders from Preschool through High School.

    PubMed

    Wei, Xin; Wagner, Mary; Christiano, Elizabeth R A; Shattuck, Paul; Yu, Jennifer W

    2014-11-01

    Little is known about how special education services received by students with Autism Spectrum Disorders (ASDs) differ by age, disability severity, and demographic characteristics. Using three national datasets, the Pre-Elementary Education Longitudinal Study (PEELS), the Special Education Elementary Longitudinal Study (SEELS), and the National Longitudinal Transition Study-2 (NLTS2), this study examined the age trends in special education services received by students with ASDs from preschool through high school. Elementary-school students with ASDs had higher odds of receiving adaptive physical education, specialized computer software or hardware, and special transportation, but lower odds of receiving learning strategies/study skills support than their preschool peers. Secondary-school students had lower odds of receiving speech/language or occupational therapy and of having a behavior management program, but higher odds of receiving mental health or social work services than their elementary-school peers. Both disability severity and demographic characteristics were associated with differences in special education service receipt rates.

  14. The pattern of antenatal visits with emphasis on gestational age at booking in Riyadh Health Centres.

    PubMed

    al-Shammari, S A; Khoja, T; Jarallah, J S

    1994-04-01

    1344 expectant mothers were selected by random sampling from the catchment population of 15 health centres in Riyadh. The health centres were taken to represent all areas of urban Riyadh. These mothers were asked to complete a pre-designed questionnaire in Arabic and undergo a structured interview by trained midwives to explore their knowledge, attitude and practice toward antenatal visits. It was found that the average gestational age at booking was 13 weeks. The number of antenatal visits achieved during the current pregnancy was 6. 97% of expectant mothers were aware of the importance of antenatal visits. Various demographic characteristics were studied in relation to the number of antenatal visits achieved and the gestational age at booking. It was found that the level of education of both husband and wife and poor obstetric history significantly affected gestational age at booking, (P-values) were less than 0.03 and 0.002 respectively). However the family income and gestational age at booking affected the number of antenatal visits (P-values were less than 0.0003 and 0.0001 respectively). The respondents' most striking reason for non-compliance was related to accessibility to health centre. 23.3% thought that the health centres were far away from their residence and they needed to involve the husbands in driving them to health centres. Recommendations were given to improve aspects of accessibility and inviting more antenatal visits in addition to improving quality of such service.

  15. Forest Service special agents, assistant special agents in charge, senior special agents, and supervisory special agents report: nationwide study

    Treesearch

    Deborah J. Chavez; Joanne F. Tynon

    2007-01-01

    This is the fourth in a series of studies to evaluate perceptions of U.S. Department of Agriculture Forest Service law enforcement personnel of the roles, responsibilities, and issues related to their jobs. An e-mail survey was administered to the 89 Forest Service special agents, assistant special agents in charge, senior special agents, and supervisory special agents...

  16. Nuclear air cleaning: the need for a change in emphasis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carbaugh, E.H.

    1982-11-01

    The nuclear industry now has over 35 years of experience in nuclear air cleaning. This experience covers technology development, system design, operations, and maintenance. Much of the past experience has been directed towards technology development with particular emphasis on high efficiency particulate air (HEPA) filters. Implementation of this technology has lagged its development by a number of years. A recent study examines the cause and frequencies of HEPA filter changeouts and failures. These data lead to a conclusion that a shift in emphasis from technology development to the training of personnel and the designing and maintaining of such systems ismore » needed. Some highlights of the data and a discussion of topics which should be addressed in training will be presented.« less

  17. Detection of mild cognitive impairment in people older than 65 years of age and its relationship to cardiovascular risk factors (DECRIVAM)

    PubMed Central

    2011-01-01

    Background Studies centered on the detection of cognitive impairment and its relationship to cardiovascular risk factors in elderly people have gained special relevance in recent years. Knowledge of the cardiovascular risk factors that may be associated to cognitive impairment could be very useful for introducing treatments in early stages - thereby possibly contributing to improve patient quality of life. The present study explores cognitive performance in people over 65 years of age in Salamanca (Spain), with special emphasis on the identification of early symptoms of cognitive impairment, with the purpose of detecting mild cognitive impairment and of studying the relationships between this clinical situation and cardiovascular risk factors. Methods/Design A longitudinal study is contemplated. The reference population will consist of 420 people over 65 years of age enrolled through randomized sampling stratified by healthcare area, and who previously participated in another study. Measurement: a) Sociodemographic variables; b) Cardiovascular risk factors; c) Comorbidity; d) Functional level for daily life activities; and e) Study of higher cognitive functions based on a neuropsychological battery especially adapted to the evaluation of elderly people. Discussion We hope that this study will afford objective information on the representative prevalence of cognitive impairment in the population over 65 years of age in Salamanca. We also hope to obtain data on the relationship between cognitive impairment and cardiovascular risk factors in this specific population group. Based on the results obtained, we also will be able to establish the usefulness of some of the screening tests applied during the study, such as the Mini-Mental State Examination and the 7 Minute Screen test. Trial registration ClinicalTrials.gov: NCT01327196 PMID:21708036

  18. A comparative study of forestry in Finland, Norway, Sweden, and the United States, with special emphasis on policy measures for nonindustrial private forests in Norway and the United States.

    Treesearch

    Berit Hauger Lindstad

    2002-01-01

    In recognition of the cultural, economic, and ecological importance of forestry in Finland, Norway, Sweden, and the United States, this paper compares forest resource data, ownership patterns, management issues, and the impact the forest sector has on the national economies of these four countries. There is particular emphasis on the analysis of policy measures that...

  19. Aging and sexuality.

    PubMed

    Yee, Lesley

    2010-10-01

    Sexuality has become a medical issue in association with aging. This is due to a number of factors, including increasing age of survival, a positive societal construct that promotes sexuality as important for quality of life as we age, and the medicalisation of sexuality with the advent of prescription medications to treat sexual dysfunction. This article reviews the factors surrounding aging and sexuality and also considers special situations with age, such as institutionalised care and the possibility of elder abuse. Normal physiological changes with aging affect both genders in terms of sexual desire and performance. Other medical conditions increase with age, and these and their treatments will impact on sexuality and the way it can be expressed. Medical practitioners require an understanding of these changes in order to find ways to optimise sexual function in older patients.

  20. Oral cleanliness and gingival health among Special Olympics athletes in Europe and Eurasia.

    PubMed

    Marks, Luc; Fernandez, Carla; Kaschke, Imke; Perlman, Steven

    2015-09-01

    Special Olympics athletes, as well as the general population of people with intellectual disabilities, are expected to have poorer gingival health. The aim of the study is to explore the prevalence of gingival signs of inflammation and its relationship to oral cleanliness and age among Special Olympics athletes from Europe and Eurasia. A retrospective longitudinal study was performed with data collected through standardized oral from 15.941 athletes from annual Special Olympics events held in 49 countries, from Europe and Eurasia between 2007 and 2012. The data was analysed descriptively, with One-Way ANOVA test and Chi-Square test. The level of significance was predetermined at a p value < 0.05. A total of 7,754 athletes presented with gingival signs (48.64%). There were no significant differences (p= 0,095) in mean gingival signs between age groups, however the association between mouth cleaning and age, was statistically significant. The data suggests that there is a high prevalence of gingival signs among individuals with special needs; over 50% in more than 20 countries. Therefore, there is a serious need for education and preventive programs for the patients, their parents and caregivers.

  1. Sports Specialization, Part II: Alternative Solutions to Early Sport Specialization in Youth Athletes.

    PubMed

    Myer, Gregory D; Jayanthi, Neeru; DiFiori, John P; Faigenbaum, Avery D; Kiefer, Adam W; Logerstedt, David; Micheli, Lyle J

    2016-01-01

    Many coaches, parents, and children believe that the best way to develop elite athletes is for them to participate in only 1 sport from an early age and to play it year-round. However, emerging evidence to the contrary indicates that efforts to specialize in 1 sport may reduce opportunities for all children to participate in a diverse year-round sports season and can lead to lost development of lifetime sports skills. Early sports specialization may also reduce motor skill development and ongoing participation in games and sports as a lifestyle choice. The purpose of this review is to employ the current literature to provide evidence-based alternative strategies that may help to optimize opportunities for all aspiring young athletes to maximize their health, fitness, and sports performance. Nonsystematic review with critical appraisal of existing literature. Clinical review. Level 4. Based on the current evidence, parents and educators should help provide opportunities for free unstructured play to improve motor skill development and youth should be encouraged to participate in a variety of sports during their growing years to influence the development of diverse motor skills. For those children who do choose to specialize in a single sport, periods of intense training and specialized sport activities should be closely monitored for indicators of burnout, overuse injury, or potential decrements in performance due to overtraining. Last, the evidence indicates that all youth should be involved in periodized strength and conditioning (eg, integrative neuromuscular training) to help them prepare for the demands of competitive sport participation, and youth who specialize in a single sport should plan periods of isolated and focused integrative neuromuscular training to enhance diverse motor skill development and reduce injury risk factors. B. © 2015 The Author(s).

  2. How Older Americans Live: An Analysis of Census Data. An Information Paper Prepared for Use by the Special Committee on Aging. United States Senate, Ninety-Ninth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    This document is an information paper prepared for the Senate Special Committee on Aging which analyzes 1980 census data on living conditions of older Americans. The analysis provides the following conclusions: (1) older women are more likely to be poor, widowed, and living alone than are older men; (3) labor force participation and median income…

  3. Complex reference values for endocrine and special chemistry biomarkers across pediatric, adult, and geriatric ages: establishment of robust pediatric and adult reference intervals on the basis of the Canadian Health Measures Survey.

    PubMed

    Adeli, Khosrow; Higgins, Victoria; Nieuwesteeg, Michelle; Raizman, Joshua E; Chen, Yunqi; Wong, Suzy L; Blais, David

    2015-08-01

    Defining laboratory biomarker reference values in a healthy population and understanding the fluctuations in biomarker concentrations throughout life and between sexes are critical to clinical interpretation of laboratory test results in different disease states. The Canadian Health Measures Survey (CHMS) has collected blood samples and health information from the Canadian household population. In collaboration with the Canadian Laboratory Initiative on Pediatric Reference Intervals (CALIPER), the data have been analyzed to determine reference value distributions and reference intervals for several endocrine and special chemistry biomarkers in pediatric, adult, and geriatric age groups. CHMS collected data and blood samples from thousands of community participants aged 3 to 79 years. We used serum samples to measure 13 immunoassay-based special chemistry and endocrine markers. We assessed reference value distributions and, after excluding outliers, calculated age- and sex-specific reference intervals, along with corresponding 90% CIs, according to CLSI C28-A3 guidelines. We observed fluctuations in biomarker reference values across the pediatric, adult, and geriatric age range, with stratification required on the basis of age for all analytes. Additional sex partitions were required for apolipoprotein AI, homocysteine, ferritin, and high sensitivity C-reactive protein. The unique collaboration between CALIPER and CHMS has enabled, for the first time, a detailed examination of the changes in various immunochemical markers that occur in healthy individuals of different ages. The robust age- and sex-specific reference intervals established in this study provide insight into the complex biological changes that take place throughout development and aging and will contribute to improved clinical test interpretation. © 2015 American Association for Clinical Chemistry.

  4. Nutrition Updates "Carotenoids and Health"

    USDA-ARS?s Scientific Manuscript database

    This symposium covered current topics in carotenoids and health, with special emphasis on healthy aging. The carotenoids covered were beta-carotene, lycopene, lutein, and beta-cryptoxanthin. Topics included the best food sources of these carotenoids, the importance of carotenoids as antioxidants an...

  5. Brief Introduction to Hepatitis B for Parents of Adopted Children

    MedlinePlus

    ... not urine or stool). Families need age-appropriate counseling on prevention of disease transmission at the time of diagnosis and at intervals throughout the child’s life, with special emphasis on the risks of sexual transmission as the child approaches adolescence. If the ...

  6. Gradient Pre-Emphasis to Counteract First-Order Concomitant Fields on Asymmetric MRI Gradient Systems

    PubMed Central

    Tao, Shengzhen; Weavers, Paul T.; Trzasko, Joshua D.; Shu, Yunhong; Huston, John; Lee, Seung-Kyun; Frigo, Louis M.; Bernstein, Matt A.

    2016-01-01

    PURPOSE To develop a gradient pre-emphasis scheme that prospectively counteracts the effects of the first-order concomitant fields for any arbitrary gradient waveform played on asymmetric gradient systems, and to demonstrate the effectiveness of this approach using a real-time implementation on a compact gradient system. METHODS After reviewing the first-order concomitant fields that are present on asymmetric gradients, a generalized gradient pre-emphasis model assuming arbitrary gradient waveforms is developed to counteract their effects. A numerically straightforward, simple to implement approximate solution to this pre-emphasis problem is derived, which is compatible with the current hardware infrastructure used on conventional MRI scanners for eddy current compensation. The proposed method was implemented on the gradient driver sub-system, and its real-time use was tested using a series of phantom and in vivo data acquired from 2D Cartesian phase-difference, echo-planar imaging (EPI) and spiral acquisitions. RESULTS The phantom and in vivo results demonstrate that unless accounted for, first-order concomitant fields introduce considerable phase estimation error into the measured data and result in images exhibiting spatially dependent blurring/distortion. The resulting artifacts are effectively prevented using the proposed gradient pre-emphasis. CONCLUSION An efficient and effective gradient pre-emphasis framework is developed to counteract the effects of first-order concomitant fields of asymmetric gradient systems. PMID:27373901

  7. Personal protective equipment use among students with special health care needs reporting injuries in school-sponsored vocational, career, and technical education programs in New Jersey.

    PubMed

    Rubenstein, Eric; Shendell, Derek; Eggert, Brain C; Marcella, Stephen W

    2014-01-01

    Students with special health care needs (SHCNs) and individualized education plans (IEPs) may be injured more often in vocational, career, and technical education (CTE) programs. No research to date considers personal protective equipment (PPE) use among students with SHCNs in school-based programs reporting injuries to agencies. Data from 1999 to 2011 on PPE use among injured students in CTE programs in public schools and private secondary schools for the disabled were analyzed; students with SHCNs were distinguished by IEP status within New Jersey Safe Schools surveilance data. Among students with IEPs using PPE, 36% of injuries occurred to body parts PPE was meant to protect. Likely injury types were cuts-lacerations and burns for students with IEPs using PPE and cuts-lacerations and sprains for students with IEPs not using PPE. Females with IEPs using PPE were injured less often than males across ages. Results suggested students with SHCNs with IEPs need further job-related training with increased emphasis on properly selecting and fitting PPE.

  8. Framework for Considering Productive Aging and Work.

    PubMed

    Schulte, Paul A; Grosch, James; Scholl, Juliann C; Tamers, Sara L

    2018-05-01

    The U.S. population is experiencing a demographic transition resulting in an aging workforce. The objective of this article is to elucidate and expand an approach to keep that workforce safe, healthy, and productive. This article elucidates the framework for the National Center for Productive Aging at Work of the National Institute for Occupational Safety and Health. Subject matter experts used a snowball method to review published literature to substantiate elements in the framework. Evidence-based literature supports a productive aging framework for the workforce involving the following elements: 1) life span perspective; 2) comprehensive and integrated approaches to occupational safety and health; 3) emphasis on positive outcomes for both workers and organizations; and 4) supportive work culture for multigenerational issues. The productive aging framework provides a foundational and comprehensive approach for addressing the aging workforce.

  9. Discovering Me: Music Activities for Special Learners.

    ERIC Educational Resources Information Center

    Thompson, Keith P.; And Others

    The book contains information on musical activities which were field tested in Project PASE (Program in the Arts for Special Education, Pennsylvania) classrooms with a wide range of exceptionalities from preschool age to adolescence. Activities are seen to help children become more aware of their bodies, feelings, and themselves; feel important…

  10. Your Guide to the New Science of Aging Well

    MedlinePlus

    ... Section Your Guide to the New Science of Aging Well Past Issues / Winter 2007 Table of Contents ... to this special section of NIH MedlinePlus on "Aging Well." Aging well is more critical than ever ...

  11. 41 CFR 101-8.709 - Special benefits for children and the elderly.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... children and the elderly. 101-8.709 Section 101-8.709 Public Contracts and Property Management Federal... § 101-8.709 Special benefits for children and the elderly. If a recipient's program or activity provides special benefits to the elderly or to children, such use of age distinctions is presumed to be necessary...

  12. 41 CFR 101-8.709 - Special benefits for children and the elderly.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... children and the elderly. 101-8.709 Section 101-8.709 Public Contracts and Property Management Federal... § 101-8.709 Special benefits for children and the elderly. If a recipient's program or activity provides special benefits to the elderly or to children, such use of age distinctions is presumed to be necessary...

  13. Energy Expenditure and Aging

    PubMed Central

    Manini, Todd M.

    2009-01-01

    The study of energy expenditure (EE) has deep roots in understanding aging and lifespan in all species. In humans, total EE decreases substantially in advanced age resulting from parallel changes in resting metabolic rate (RMR) and activity EE. For RMR, this reduction appears to be due to a reduction in organ mass and specific metabolic rates of individual tissues. However, these anatomical changes explain very little regarding the decline in activity EE, which is governed by both genetic and environmental sources. The biological control centers for activity EE are closely coupled with body mass fluctuations and seem to originate in the brain. Several candidate neuromodulators may be involved in the age-related reduction of activity EE that include: orexin, agouti-related proteins and dopaminergic pathways. Unfortunately, the existing body of research has primarily focused on how neuromodulators influence weight gain and only a few studies have been performed in aging models. Recent evidence suggests that activity EE has an important role in dictating lifespan and thus places emphasis on future research to uncover the underlying biological mechanisms. The study of EE continues to unlock clues to aging. PMID:19698803

  14. Introduction to special section: Science and technology of over-the-horizon radar

    NASA Astrophysics Data System (ADS)

    Berkey, F. Tom

    1998-07-01

    The rationale for the development of over-the-horizon (OTH) radar systems operating at frequencies in the HF band arose out of a perceived need for an early-warning defense network. That need changed with the end of the Cold War; however, today OTH radars play a major role in the CounterDrug Program for the interdiction of drug-smuggling aircraft. This special section of Radio Science is devoted to a review of OTH radar technology, with emphasis on contemporary developments in this field. The collection of papers presented here has evolved largely from research and development efforts directed to improving the performance of OTH radar systems deployed both in the United States and in Australia.

  15. 20 CFR 416.1260 - Special resource provision for recipients under a State plan.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Special resource provision for recipients under a State plan. 416.1260 Section 416.1260 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Resources and Exclusions § 416.1260 Special...

  16. The Association of Sport Specialization and Training Volume With Injury History in Youth Athletes.

    PubMed

    Post, Eric G; Trigsted, Stephanie M; Riekena, Jeremy W; Hetzel, Scott; McGuine, Timothy A; Brooks, M Alison; Bell, David R

    2017-05-01

    Recommendations exist to encourage safe youth participation in sport. These recommendations include not specializing in 1 sport, limiting participation to less than 8 months per year, and limiting participation to fewer hours per week than a child's age. However, limited evidence exists to support or refute these recommendations. High levels of specialization will be associated with a history of injuries and especially overuse injuries, independent of age, sex, or weekly sport training hours. Athletes who exceed current sport volume recommendations will be more likely to have a history of injuries and overuse injuries. Case-control study; Level of evidence, 3. Youth athletes (n = 2011; 989 female and 1022 male; 12-18 years of age) completed a questionnaire regarding their specialization status, yearly and weekly sport participation volume, and injury history. Specialization was classified as low, moderate, or high using a previously utilized 3-point scale. Athletes were classified into groups based on either meeting or exceeding current volume recommendations (months per year and hours per week). Odds ratios (ORs) and 95% CIs were calculated to investigate associations of specialization and volume of participation with a history of sport-related injuries in the past year ( P ≤ .05). Highly specialized athletes were more likely to report a previous injury of any kind ( P < .001; OR, 1.59; 95% CI, 1.26-2.02) or an overuse injury ( P = .011; OR, 1.45; 95% CI, 1.07-1.99) in the previous year compared with athletes in the low specialization group. Athletes who played their primary sport more than 8 months of the year were more likely to report an upper extremity overuse injury ( P = .04; OR, 1.68; 95% CI, 1.06-2.80) or a lower extremity overuse injury ( P = .001; OR, 1.66; 95% CI, 1.22-2.30). Athletes who participated in their primary sport for more hours per week than their age (ie, a 16-year-old athlete who participated in his or her primary sport for more than 16 h

  17. Redefining Aging in HIV Infection Using Phenotypes.

    PubMed

    Stoff, David M; Goodkin, Karl; Jeste, Dilip; Marquine, Maria

    2017-10-01

    This article critically reviews the utility of "phenotypes" as behavioral descriptors in aging/HIV research that inform biological underpinnings and treatment development. We adopt a phenotypic redefinition of aging conceptualized within a broader context of HIV infection and of aging. Phenotypes are defined as dimensions of behavior, closely related to fundamental mechanisms, and, thus, may be more informative than chronological age. Primary emphasis in this review is given to comorbid aging and cognitive aging, though other phenotypes (i.e., disability, frailty, accelerated aging, successful aging) are also discussed in relation to comorbid aging and cognitive aging. The main findings that emerged from this review are as follows: (1) the phenotypes, comorbid aging and cognitive aging, are distinct from each other, yet overlapping; (2) associative relationships are the rule in HIV for comorbid and cognitive aging phenotypes; and (3) HIV behavioral interventions for both comorbid aging and cognitive aging have been limited. Three paths for research progress are identified for phenotype-defined aging/HIV research (i.e., clinical and behavioral specification, biological mechanisms, intervention targets), and some important research questions are suggested within each of these research paths.

  18. Gradient pre-emphasis to counteract first-order concomitant fields on asymmetric MRI gradient systems.

    PubMed

    Tao, Shengzhen; Weavers, Paul T; Trzasko, Joshua D; Shu, Yunhong; Huston, John; Lee, Seung-Kyun; Frigo, Louis M; Bernstein, Matt A

    2017-06-01

    To develop a gradient pre-emphasis scheme that prospectively counteracts the effects of the first-order concomitant fields for any arbitrary gradient waveform played on asymmetric gradient systems, and to demonstrate the effectiveness of this approach using a real-time implementation on a compact gradient system. After reviewing the first-order concomitant fields that are present on asymmetric gradients, we developed a generalized gradient pre-emphasis model assuming arbitrary gradient waveforms to counteract their effects. A numerically straightforward, easily implemented approximate solution to this pre-emphasis problem was derived that was compatible with the current hardware infrastructure of conventional MRI scanners for eddy current compensation. The proposed method was implemented on the gradient driver subsystem, and its real-time use was tested using a series of phantom and in vivo data acquired from two-dimensional Cartesian phase-difference, echo-planar imaging, and spiral acquisitions. The phantom and in vivo results demonstrated that unless accounted for, first-order concomitant fields introduce considerable phase estimation error into the measured data and result in images with spatially dependent blurring/distortion. The resulting artifacts were effectively prevented using the proposed gradient pre-emphasis. We have developed an efficient and effective gradient pre-emphasis framework to counteract the effects of first-order concomitant fields of asymmetric gradient systems. Magn Reson Med 77:2250-2262, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  19. 40 CFR 7.165 - Special benefits for children and the elderly.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... elderly. 7.165 Section 7.165 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL... Discrimination Prohibited on the Basis of Age § 7.165 Special benefits for children and the elderly. If a recipient operating a program which serves the elderly or children in addition to persons of other ages...

  20. 40 CFR 7.165 - Special benefits for children and the elderly.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... elderly. 7.165 Section 7.165 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL... Discrimination Prohibited on the Basis of Age § 7.165 Special benefits for children and the elderly. If a recipient operating a program which serves the elderly or children in addition to persons of other ages...

  1. State Plan for Special Education and Services.

    ERIC Educational Resources Information Center

    Hawaii State Dept. of Education, Honolulu. Office of Instructional Services.

    Presented is Hawaii's state plan for the provision of special education and services to all handicapped children under 20 years of age by 1980-81. Explained in Chapter I are the philosophic and legal bases for the plan, including the right to equal educational opportunities for children with the following handicapping conditions: mental…

  2. Phonological Working Memory of Children in Two German Special Schools

    ERIC Educational Resources Information Center

    Hasselhorn, Marcus; Mahler, Claudia

    2007-01-01

    In two studies, 10-year-olds from 2 German special schools as well as typically developing children of the same chronological age (CA controls) or the same mental age (MA controls) were compared on several aspects of working memory functions (i.e., size and input quality of the phonological store, speed and automatic activation of the subvocal…

  3. Constructions of Violence and Masculinity in the Digital Age

    ERIC Educational Resources Information Center

    Patterson, Jennifer

    2013-01-01

    This chapter examines a specific aspect of digital media use, namely the viewing of violent content amongst a male adolescent cohort aged 15-17 years. It is a qualitative study that examines the online practices of fourteen male adolescents, with particular emphasis placed on their understanding of violence. The participants offer the researcher…

  4. Gender considerations in ventilatory and metabolic development in rats: special emphasis on the critical period

    PubMed Central

    LIU, QIULI; WONG-RILEY, MARGARET T.T

    2013-01-01

    In rats, a critical period exists around postnatal day (P) 12-13, when an imbalance between heightened inhibition and suppressed excitation led to a weakened ventilatory and metabolic response to acute hypoxia. An open question was whether the two genders follow the same or different developmental trends throughout the first 3 postnatal weeks and whether the critical period exists in one or both genders. The present large-scale, in-depth ventilatory and metabolic study was undertaken to address this question. Our data indicated that: 1) the ventilatory and metabolic rates in both normoxia and acute hypoxia were comparable between the two genders from P0 to P21; thus, gender was never significant as a main effect; and 2) the age effect was highly significant in all parameters studies for both genders, and both genders exhibited a significantly weakened response to acute hypoxia during the critical period. Thus, the two genders have comparable developmental trends, and the critical period exists in both genders in rats. PMID:23797186

  5. Progressive and regressive developmental changes in neural substrates for face processing: Testing specific predictions of the Interactive Specialization account

    PubMed Central

    Joseph, Jane E.; Gathers, Ann D.; Bhatt, Ramesh S.

    2010-01-01

    Face processing undergoes a fairly protracted developmental time course but the neural underpinnings are not well understood. Prior fMRI studies have only examined progressive changes (i.e., increases in specialization in certain regions with age), which would be predicted by both the Interactive Specialization (IS) and maturational theories of neural development. To differentiate between these accounts, the present study also examined regressive changes (i.e., decreases in specialization in certain regions with age), which is predicted by the IS but not maturational account. The fMRI results show that both progressive and regressive changes occur, consistent with IS. Progressive changes mostly occurred in occipital-fusiform and inferior frontal cortex whereas regressive changes largely emerged in parietal and lateral temporal cortices. Moreover, inconsistent with the maturational account, all of the regions involved in face viewing in adults were active in children, with some regions already specialized for face processing by 5 years of age and other regions activated in children but not specifically for faces. Thus, neurodevelopment of face processing involves dynamic interactions among brain regions including age-related increases and decreases in specialization and the involvement of different regions at different ages. These results are more consistent with IS than maturational models of neural development. PMID:21399706

  6. Trustworthiness in Evaluation Practice: An Emphasis on the Relational

    ERIC Educational Resources Information Center

    Rallis, Sharon F.; Rossman, Gretchen B.; Gajda, Rebecca

    2007-01-01

    As canons for trustworthiness developed explicitly in the discourse of qualitative inquiry, the emphasis was on procedural matters rather than fundamentally relational ones. A nod was made to the relational in such strategies as "member checks" but the issues of how the evaluator actually relates to participants and to the larger communities of…

  7. Long-term solar UV radiation reconstructed by ANN modelling with emphasis on spatial characteristics of input data

    NASA Astrophysics Data System (ADS)

    Feister, U.; Junk, J.; Woldt, M.; Bais, A.; Helbig, A.; Janouch, M.; Josefsson, W.; Kazantzidis, A.; Lindfors, A.; den Outer, P. N.; Slaper, H.

    2008-06-01

    Artificial Neural Networks (ANN) are efficient tools to derive solar UV radiation from measured meteorological parameters such as global radiation, aerosol optical depths and atmospheric column ozone. The ANN model has been tested with different combinations of data from the two sites Potsdam and Lindenberg, and used to reconstruct solar UV radiation at eight European sites by more than 100 years into the past. Special emphasis will be given to the discussion of small-scale characteristics of input data to the ANN model. Annual totals of UV radiation derived from reconstructed daily UV values reflect interannual variations and long-term patterns that are compatible with variabilities and changes of measured input data, in particular global dimming by about 1980/1990, subsequent global brightening, volcanic eruption effects such as that of Mt. Pinatubo, and the long-term ozone decline since the 1970s. Patterns of annual erythemal UV radiation are very similar at sites located at latitudes close to each other, but different patterns occur between UV radiation at sites in different latitude regions.

  8. 20 CFR 408.214 - Are you age 65?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Are you age 65? 408.214 Section 408.214 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR CERTAIN WORLD WAR II VETERANS SVB Qualification and Entitlement Age § 408.214 Are you age 65? You become age 65 on the first moment of the day...

  9. 20 CFR 408.214 - Are you age 65?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Are you age 65? 408.214 Section 408.214 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR CERTAIN WORLD WAR II VETERANS SVB Qualification and Entitlement Age § 408.214 Are you age 65? You become age 65 on the first moment of the day...

  10. Are the special educational needs of children in their first year in primary school in Ireland being identified: a cross-sectional study.

    PubMed

    Curtin, Margaret; Baker, Denise; Staines, Anthony; Perry, Ivan J

    2014-02-19

    If the window of opportunity presented by the early years is missed, it becomes increasingly difficult to create a successful life-course. A biopsychosocial model of special educational need with an emphasis on participation and functioning moves the frame of reference from the clinic to the school and the focus from specific conditions to creating supportive environments cognisant of the needs of all children. However, evidence suggests that an emphasis on diagnosed conditions persists and that the needs of children who do not meet these criteria are not identified.The Early Development Instrument (EDI) is a well-validated, teacher-completed population-level measure of five domains of child development. It is uniquely placed, at the interface between health and education, to explore the developmental status of children with additional challenges within a typically developing population. The aim of this study was to examine the extent to which the special educational needs of children in their first year of formal education have been identified. This cross-sectional study was conducted in Ireland in 2011. EDI (teacher completed) scores were calculated for 1344 children. Data were also collected on special needs and on children identified by the teacher as needing assessment. Mean developmental scores were compared using one-way ANOVA. Eighty-three children in the sample population (6.2%) had identified special educational needs. A further 132 children were judged by the teacher as needing assessment. Children with special needs had lower mean scores than typically developing children, in all five developmental domains. Children considered by the teacher as needing assessment also had lower scores, which were not significantly different from those of children with special needs. Speech, emotional or behavioural difficulties were the most commonly reported problems among children needing further assessment. There was also a social gradient among this group. A small

  11. 78 FR 32670 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-31

    ... Scientific Review Special Emphasis Panel; Fellowships: Brain Disorders, Language, Communication, and Related...: Center for Scientific Review Special Emphasis Panel; PAR Panel: Brain Disorders in the Developing World... Review Special Emphasis Panel; Small Business: Health Informatics. Date: June 28, 2013. Time: 8:30 a.m...

  12. 78 FR 33428 - National Institute of Allergy and Infectious Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-04

    ... Infectious Diseases Special Emphasis Panel; ``Clinical Trials Units for NIAID Networks'' (Meeting 3). Date... Institute of Allergy and Infectious Diseases Special Emphasis Panel; Clinical Trials Units for NIAID... Diseases Special Emphasis Panel; Clinical Trials Units for NIAID Networks. Date: June 28, 2013. Time: 10:00...

  13. 75 FR 14178 - Statement of Organization, Functions, and Delegations of Authority

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-24

    ... Title VII, Civil Rights Act of 1964; Age Discrimination in Employment Act (ADEA); Rehabilitation Act of... development of comprehensive special emphasis programs to assure full recognition of the needs of women... of employment of women and minorities at CDC and maintains liaison with DHHS and other organizations...

  14. 77 FR 61770 - Center for Scientific Review; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-11

    ... commercial property such as patentable material, and personal information concerning individuals associated... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel; Cancer...: Multidisciplinary Studies of HIV/AIDS and Aging. Date: November 9, 2012. Time: 10 a.m. to 6 p.m. Agenda: To review...

  15. EMPHASIS/Nevada UTDEM user guide. Version 2.0.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Turner, C. David; Seidel, David Bruce; Pasik, Michael Francis

    The Unstructured Time-Domain ElectroMagnetics (UTDEM) portion of the EMPHASIS suite solves Maxwell's equations using finite-element techniques on unstructured meshes. This document provides user-specific information to facilitate the use of the code for applications of interest. UTDEM is a general-purpose code for solving Maxwell's equations on arbitrary, unstructured tetrahedral meshes. The geometries and the meshes thereof are limited only by the patience of the user in meshing and by the available computing resources for the solution. UTDEM solves Maxwell's equations using finite-element method (FEM) techniques on tetrahedral elements using vector, edge-conforming basis functions. EMPHASIS/Nevada Unstructured Time-Domain ElectroMagnetic Particle-In-Cell (UTDEM PIC) ismore » a superset of the capabilities found in UTDEM. It adds the capability to simulate systems in which the effects of free charge are important and need to be treated in a self-consistent manner. This is done by integrating the equations of motion for macroparticles (a macroparticle is an object that represents a large number of real physical particles, all with the same position and momentum) being accelerated by the electromagnetic forces upon the particle (Lorentz force). The motion of these particles results in a current, which is a source for the fields in Maxwell's equations.« less

  16. Special Section Guest Editorial: Laser Damage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gruzdev, Vitaly E.; Shinn, Michelle D.

    2012-11-09

    Laser damage of optical materials, first reported in 1964, continues to limit the output energy and power of pulsed and continuous-wave laser systems. In spite of some 48 years of research in this area, interest from the international laser community to laser damage issues remains at a very high level and does not show any sign of decreasing. Moreover, it grows with the development of novel laser systems, for example, ultrafast and short-wavelength lasers that involve new damage effects and specific mechanisms not studied before. This interest is evident from the high level of attendance and presentations at the annualmore » SPIE Laser Damage Symposium (aka, Boulder Damage Symposium) that has been held in Boulder, Colorado, since 1969. This special section of Optical Engineering is the first one devoted to the entire field of laser damage rather than to a specific part. It is prepared in response to growing interest from the international laser-damage community. Some papers in this special section were presented at the Laser Damage Symposium; others were submitted in response to the general call for papers for this special section. The 18 papers compiled into this special section represent many sides of the broad field of laser-damage research. They consider theoretical studies of the fundamental mechanisms of laser damage including laser-driven electron dynamics in solids (O. Brenk and B. Rethfeld; A. Nikiforov, A. Epifanov, and S. Garnov; T. Apostolova et al.), modeling of propagation effects for ultrashort high-intensity laser pulses (J. Gulley), an overview of mechanisms of inclusion-induced damage (M. Koldunov and A. Manenkov), the formation of specific periodic ripples on a metal surface by femtosecond laser pulses (M. Ahsan and M. Lee), and the laser-plasma effects on damage in glass (Y. Li et al). Material characterization is represented by the papers devoted to accurate and reliable measurements of absorption with special emphasis on thin films (C. M

  17. Parasites and phytoplankton, with special emphasis on dinoflagellate infections.

    PubMed

    Park, Myung Gil; Yih, Wonho; Coats, D Wayne

    2004-01-01

    Planktonic members of most algal groups are known to harbor intracellular symbionts, including viruses, bacteria, fungi, and protozoa. Among the dinoflagellates, viral and bacterial associations were recognized a quarter century ago, yet their impact on host populations remains largely unresolved. By contrast, fungal and protozoan infections of dinoflagellates are well documented and generally viewed as playing major roles in host population dynamics. Our understanding of fungal parasites is largely based on studies for freshwater diatoms and dinoflagellates, although fungal infections are known for some marine phytoplankton. In freshwater systems, fungal chytrids have been linked to mass mortalities of host organisms, suppression or retardation of phytoplankton blooms, and selective effects on species composition leading to successional changes in plankton communities. Parasitic dinoflagellates of the genus Amoebophrya and the newly described Perkinsozoa, Parvilucifera infectans, are widely distributed in coastal waters of the world where they commonly infect photosynthetic and heterotrophic dinoflagellates. Recent work indicates that these parasites can have significant impacts on host physiology, behavior, and bloom dynamics. Thus, parasitism needs to be carefully considered in developing concepts about plankton dynamics and the flow of material in marine food webs.

  18. Biodiesel production with special emphasis on lipase-catalyzed transesterification.

    PubMed

    Bisen, Prakash S; Sanodiya, Bhagwan S; Thakur, Gulab S; Baghel, Rakesh K; Prasad, G B K S

    2010-08-01

    The production of biodiesel by transesterification employing acid or base catalyst has been industrially accepted for its high conversion and reaction rates. Downstream processing costs and environmental problems associated with biodiesel production and byproducts recovery have led to the search for alternative production methods. Recently, enzymatic transesterification involving lipases has attracted attention for biodiesel production as it produces high purity product and enables easy separation from the byproduct, glycerol. The use of immobilized lipases and immobilized whole cells may lower the overall cost, while presenting less downstream processing problems, to biodiesel production. The present review gives an overview on biodiesel production technology and analyzes the factors/methods of enzymatic approach reported in the literature and also suggests suitable method on the basis of evidence for industrial production of biodiesel.

  19. Special Issue: Gene Therapy with Emphasis on RNA Interference

    PubMed Central

    Lundstrom, Kenneth

    2015-01-01

    Gene therapy was originally thought to cover replacement of malfunctioning genes in treatment of various diseases. Today, the field has been expanded to application of viral and non-viral vectors for delivery of recombinant proteins for the compensation of missing or insufficient proteins, anti-cancer genes and proteins for destruction of tumor cells, immunostimulatory genes and proteins for stimulation of the host defense system against viral agents and tumors. Recently, the importance of RNA interference and its application in gene therapy has become an attractive alternative for drug development. PMID:26447255

  20. Preparing Teachers for Urban Students Who Have Been Labeled as Having Special Needs

    ERIC Educational Resources Information Center

    Banks, Tachelle; Obiakor, Festus; Algozzine, Bob

    2013-01-01

    Preparing teachers to work in urban public schools--and to remain there--is a daunting challenge. In an age plagued with the overrepresentation of culturally and linguistically diverse (CLD) students placed in special education programs, it is important that teacher preparation programs within the field of special education devote attention to the…