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Sample records for agitation inventory cmai

  1. Agitation in Dementia: Relation to Core Cerebrospinal Fluid Biomarker Levels

    PubMed Central

    Bloniecki, Victor; Aarsland, Dag; Cummings, Jeffrey; Blennow, Kaj; Freund-Levi, Yvonne

    2014-01-01

    Background The objective of this study was to examine the associations of agitation with the cerebrospinal fluid dementia biomarkers total-tau (T-tau), phosphorylated-tau (P-tau) and Aβ1-42. Methods One hundred patients (mean age ± SD, 78.6 ± 7.5 years) with dementia and neuropsychiatric symptoms, of whom 67% were female, were included. Agitation was measured using the Cohen-Mansfield Agitation Inventory (CMAI; 46.5 ± 11.8 points). Results Total CMAI correlated with T-tau [rs (31) = 0.36, p = 0.04] and P-tau [rs (31) = 0.35, p = 0.05] in patients with Alzheimer's disease (AD; n = 33) but not in the total dementia population (n = 95). Conclusions Our results suggest that tau-mediated pathology including neurofibrillary tangles and the intensity of the disease process might be associated with agitation in AD. PMID:25298777

  2. Change in agitation in Alzheimer's disease in the placebo arm of a 9-week controlled trial

    PubMed Central

    Drye, Lea T.; Porsteinsson, Anton P.; Pollock, Bruce G.; Devanand, D.P.; Frangakis, Constantine; Ismail, Zahinoor; Marano, Christopher; Meinert, Curtis L.; Mintzer, Jacobo E.; Munro, Cynthia A.; Pelton, Gregory; Rabins, Peter V.; Schneider, Lon S.; Shade, David M.; Weintraub, Daniel; Newell, Jeffery; Yesavage, Jerome; Lyketsos, Constantine G.

    2015-01-01

    Background Placebo responses raise significant challenges for design of clinical trials. We report changes in agitation outcomes in the placebo arm of a recent trial of citalopram for agitation in Alzheimer's disease (AD). Methods In the Citalopram for Agitation in Alzheimer's Disease (Cit AD) study, all participants and caregivers received a psychosocial intervention and 92 were assigned to placebo for 9 weeks. Outcomes included Neurobehavioral Rating Scale agitation subscale (NBRS-A), modified Alzheimer Disease Cooperative Study-Clinical Global Impression of Change (CGIC), Cohen-Mansfield Agitation Inventory (CMAI), the Neuropsychiatric Inventory (NPI) Agitation/Aggression domain (NPI A/A) and Total (NPI-Total) and ADLs. Continuous outcomes were analyzed with mixed-effects modeling and dichotomous outcomes with logistic regression. Results Agitation outcomes improved over 9 weeks: NBRS-A mean (SD) decreased from 7.8 (3.0) at baseline to 5.4 (3.2), CMAI from 28.7 (6.7) to 26.7 (7.4), NPI A/A from 8.0 (2.4) to 4.9 (3.8), and NPI-Total from 37.3 (17.7) to 28.4 (22.1). The proportion of CGI-C agitation responders ranged from 21 to 29% and was significantly different from zero. MMSE improved from 14.4 (6.9) to 15.7 (7.2) and ADLs similarly improved. Most of the improvement was observed by 3 weeks and was sustained through 9 weeks. The major predictor of improvement in each agitation measure was a higher baseline score in that measure. Conclusions We observed significant placebo response which may be due to regression to the mean, response to a psychosocial intervention, natural course of symptoms, or nonspecific benefits of participation in a trial. PMID:26305876

  3. Efficacy of Memantine for Agitation in Alzheimer’s Dementia: A Randomised Double-Blind Placebo Controlled Trial

    PubMed Central

    Fox, Chris; Crugel, Monica; Maidment, Ian; Auestad, Bjorn Henrik; Coulton, Simon; Treloar, Adrian; Ballard, Clive; Boustani, Malaz; Katona, Cornelius; Livingston, Gill

    2012-01-01

    Background Agitation in Alzheimer’s disease (AD) is common and associated with poor patient life-quality and carer distress. The best evidence-based pharmacological treatments are antipsychotics which have limited benefits with increased morbidity and mortality. There are no memantine trials in clinically significant agitation but post-hoc analyses in other populations found reduced agitation. We tested the primary hypothesis, memantine is superior to placebo for clinically significant agitation, in patients with moderate-to-severe AD. Methods and Findings We recruited 153 participants with AD and clinically significant agitation from care-homes or hospitals for a double-blind randomised-controlled trial and 149 people started the trial of memantine versus placebo. The primary outcome was 6 weeks mixed model autoregressive analysis of Cohen-Mansfield Agitation Inventory (CMAI). Secondary outcomes were: 12 weeks CMAI; 6 and 12 weeks Neuropsychiatric symptoms (NPI), Clinical Global Impression Change (CGI-C), Standardised Mini Mental State Examination, Severe Impairment Battery. Using a mixed effects model we found no significant differences in the primary outcome, 6 weeks CMAI, between memantine and placebo (memantine lower −3.0; −8.3 to 2.2, p = 0.26); or 12 weeks CMAI; or CGI-C or adverse events at 6 or 12 weeks. NPI mean difference favoured memantine at weeks 6 (−6.9; −12.2 to −1.6; p = 0.012) and 12 (−9.6; −15.0 to −4.3 p = 0.0005). Memantine was significantly better than placebo for cognition. The main study limitation is that it still remains to be determined whether memantine has a role in milder agitation in AD. Conclusions Memantine did not improve significant agitation in people with in moderate-to-severe AD. Future studies are urgently needed to test other pharmacological candidates in this group and memantine for neuropsychiatric symptoms. Trial Registration ClinicalTrials.gov NCT00371059 Trial Registration International

  4. Effect of Citalopram on Agitation in Alzheimer's Disease – The CitAD Randomized Controlled Trial

    PubMed Central

    Porsteinsson, Anton P.; Drye, Lea T.; Pollock, Bruce G.; Devanand, D.P.; Frangakis, Constantine; Ismail, Zahinoor; Marano, Christopher; Meinert, Curtis L.; Mintzer, Jacobo E.; Munro, Cynthia A.; Pelton, Gregory; Rabins, Peter V.; Rosenberg, Paul B.; Schneider, Lon S.; Shade, David M.; Weintraub, Daniel; Yesavage, Jerome; Lyketsos, Constantine G.

    2014-01-01

    Importance Agitation is common, persistent, and associated with adverse consequences for patients with Alzheimer's disease (AD). Pharmacological treatment options, including antipsychotics are not satisfactory. Objective The primary objective was to evaluate the efficacy of citalopram for agitation in patients with AD. Key secondary objectives examined effects of citalopram on function, caregiver distress, safety, cognitive safety, and tolerability. Design, Setting and Participants The Citalopram for Agitation in Alzheimer's Disease Study (CitAD) was a multicenter, randomized, placebo-controlled, double-blind, parallel group trial that enrolled 186 patients with probable AD and clinically significant agitation from eight academic centers in the US and Canada from August 2009 to January 2013. Interventions Participants (n=186) were randomized to receive a psychosocial intervention plus either citalopram (n=94) or placebo (n=92) for 9 weeks. Dose began at 10 mg/d with planned titration to 30 mg/d over 3 weeks based on response and tolerability. Main Outcomes and Measures Primary outcome measures were the Neurobehavioral Rating Scale, agitation subscale (NBRS-A) and the modified Alzheimer Disease Cooperative Study-Clinical Global Impression of Change (mADCS-CGIC) Other outcomes were the Cohen-Mansfield Agitation Inventory (CMAI), Neuropsychiatric Inventory (NPI), activities of daily living (ADLs), caregiver distress, cognitive safety (MMSE), and adverse events. Results Participants on citalopram showed significant improvement compared to placebo on both primary outcome measures. NBRS-A estimated treatment difference at week 9 (citalopram minus placebo) was −0.93 [95% CI: −1.80 to −0.06], p = 0.036. mADCS-CGIC results showed 40% of citalopram participants having moderate or marked improvement from baseline compared to 26% on placebo, with estimated treatment effect (odds ratio of being at or better than a given CGIC category) of 2.13 [95% CI 1.23 to 3.69], p = 0

  5. The Brazilian version of the Neuropsychiatric Inventory-Clinician rating (NPI-C): Reliability and validity in dementia

    PubMed Central

    Stella, Florindo; Forlenza, Orestes Vicente; Laks, Jerson; de Andrade, Larissa Pires; Ljubetic Avendaño, Michelle A.; Gasparetto Sé, Elisandra Villela; de Castilho Cação, João; Lyketsos, Constantine G.; de Medeiros, Kate

    2014-01-01

    Background Patients with dementia may be unable to describe their symptoms, and caregivers frequently suffer emotional burden that can interfere with judgment of the patient's behavior. The Neuropsychiatric Inventory-Clinician Rating Scale (NPI-C) is a comprehensive and versatile instrument to assess neuropsychiatric symptoms (NPS) in dementia. In the NPI-C, the clinician incorporates information from caregiver and patient interviews, and any other relevant available data to accurately measure NPS. The present study is a followup to the original, cross-national NPI-C validation evaluating the reliability and concurrent validity of NPI-C in quantifying psychopathological symptoms in dementia in a large Brazilian cohort. Methods Two blind raters evaluated 312 participants (156 patient-knowledgeable informant dyads) with the NPI-C totaling 624 observations in 5 Brazilian centers. Inter-rater reliability was determined through calculation of intraclass correlation coefficients for the NPI-C domains and traditional NPI. Convergent validity included correlations of specific domains of the NPI-C with the Brief Psychiatric Rating Scale (BPRS); the Cohen Mansfield Agitation Index (CMAI); the Cornell Scale for Depression in Dementia (CSDD); and the Apathy Inventory (AI). Results Inter-rater reliability was strong for all NPI-C domains. There were high correlations between NPI-C/Delusions and BPRS; NPI-C/Apathy-Indifference with the AI; NPI-C/Depression-Dysphoria with the CSDD; NPI-C/Agitation with the CMAI; and NPI-C/Aggression with the CMAI. There was moderate correlation between the NPI-C/Aberrant Vocalizations and CMAI and the NPI-C/Hallucinations with the BPRS. Conclusion The NPI-C is a comprehensive tool which provides accurate measurement of NPS in dementia with high concurrent validity and inter-rater reliability in the Brazilian setting. In addition to universal assessment, the NPI-C can be completed by individual domains. PMID:23763895

  6. Using Personality Inventories To Identify Thugs and Agitators: Applied Psychology's Contribution to the War against Labor.

    ERIC Educational Resources Information Center

    Zickar, Michael J.

    2001-01-01

    In the 1930s-1940s, personality inventories measuring psychopathology were used to identify job applicants who might be union sympathizers. Some managers believed that engagement in union activity correlated with psychological problems. Industrial psychologists' involvement in this practice raises ethical questions. (Contains 93 references.) (SK)

  7. Pain, agitation, and behavioural problems in people with dementia admitted to general hospital wards: a longitudinal cohort study

    PubMed Central

    Sampson, Elizabeth L.; White, Nicola; Lord, Kathryn; Leurent, Baptiste; Vickerstaff, Victoria; Scott, Sharon; Jones, Louise

    2015-01-01

    Abstract Pain is underdetected and undertreated in people with dementia. We aimed to investigate the prevalence of pain in people with dementia admitted to general hospitals and explore the association between pain and behavioural and psychiatric symptoms of dementia (BPSD). We conducted a longitudinal cohort study of 230 people, aged above 70, with dementia and unplanned medical admissions to 2 UK hospitals. Participants were assessed at baseline and every 4 days for self-reported pain (yes/no question and FACES scale) and observed pain (Pain Assessment in Advanced Dementia scale [PAINAD]) at movement and at rest, for agitation (Cohen–Mansfield Agitating Inventory [CMAI]) and BPSD (Behavioural Pathology in Alzheimer Disease Scale [BEHAVE-AD]). On admission, 27% of participants self-reported pain rising to 39% on at least 1 occasion during admission. Half of them were able to complete the FACES scale, this proportion decreasing with more severe dementia. Using the PAINAD, 19% had pain at rest and 57% had pain on movement on at least 1 occasion (in 16%, this was persistent throughout the admission). In controlled analyses, pain was not associated with CMAI scores but was strongly associated with total BEHAVE-AD scores, both when pain was assessed on movement (β = 0.20, 95% confidence interval [CI] = 0.07-0.32, P = 0.002) and at rest (β = 0.41, 95% CI = 0.14-0.69, P = 0.003). The association was the strongest for aggression and anxiety. Pain was common in people with dementia admitted to the acute hospital and associated with BPSD. Improved pain management may reduce distressing behaviours and improve the quality of hospital care for people with dementia. PMID:25790457

  8. Pain, agitation, and behavioural problems in people with dementia admitted to general hospital wards: a longitudinal cohort study.

    PubMed

    Sampson, Elizabeth L; White, Nicola; Lord, Kathryn; Leurent, Baptiste; Vickerstaff, Victoria; Scott, Sharon; Jones, Louise

    2015-04-01

    Pain is underdetected and undertreated in people with dementia. We aimed to investigate the prevalence of pain in people with dementia admitted to general hospitals and explore the association between pain and behavioural and psychiatric symptoms of dementia (BPSD). We conducted a longitudinal cohort study of 230 people, aged above 70, with dementia and unplanned medical admissions to 2 UK hospitals. Participants were assessed at baseline and every 4 days for self-reported pain (yes/no question and FACES scale) and observed pain (Pain Assessment in Advanced Dementia scale [PAINAD]) at movement and at rest, for agitation (Cohen-Mansfield Agitating Inventory [CMAI]) and BPSD (Behavioural Pathology in Alzheimer Disease Scale [BEHAVE-AD]). On admission, 27% of participants self-reported pain rising to 39% on at least 1 occasion during admission. Half of them were able to complete the FACES scale, this proportion decreasing with more severe dementia. Using the PAINAD, 19% had pain at rest and 57% had pain on movement on at least 1 occasion (in 16%, this was persistent throughout the admission). In controlled analyses, pain was not associated with CMAI scores but was strongly associated with total BEHAVE-AD scores, both when pain was assessed on movement (β = 0.20, 95% confidence interval [CI] = 0.07-0.32, P = 0.002) and at rest (β = 0.41, 95% CI = 0.14-0.69, P = 0.003). The association was the strongest for aggression and anxiety. Pain was common in people with dementia admitted to the acute hospital and associated with BPSD. Improved pain management may reduce distressing behaviours and improve the quality of hospital care for people with dementia.

  9. Reducing agitator energy consumption without sacrificing agitation

    SciTech Connect

    Golobic, R.A.; Derrickson, G.S.

    1982-01-01

    Rising energy costs and their increasing net effect on the cost of a mineral product requires that every aspect of processing-plant operations reduce consumed horsepower without sacrificing the grade of the product. This paper addresses two principles in the design and selection of axial-flow agitator propellers that contribute to significant reductions in required horsepower. The first of these involves the use of good design principles. The swirling wake generated by an agitator propeller induces losses in the pumping action. By designing an agitator of proper twist and shape one can minimize these losses. Depending upon the design chosen for comparison, these losses can be reduced by 30 to 50% without any sacrifice in pumping or without increasing the complexity of the design. The second aspect involves an appropriate selection of the agitator propeller diameter. The required horsepower can be significantly reduced by using a propeller of larger diameter while operating it at a lower revolutions per minute (RPM) with no sacrifice in the pumping. 3 references, 2 figures, 2 tables.

  10. Agitation apparatus. [Patent application

    DOEpatents

    Beets, A.L.; Lewis, B.E. Jr.

    1982-03-12

    Agitation apparatus includes a tank with a cylindrical upper portion, a frustoconical intermediate portion, and a cylindrical lower portion, a lift tube extending from the upper portion of the tank to a point near an end cap attached to the lower portion of the tank, the lift tube being concentric with the lower portion of the tank to provide a flow passage there between, and a plurality of air supply conduits extending along the lift tube and spaced apart around its perimeter, these air supply conduits terminating adjacent the lower end of the lift tube. Air discharged from the lower ends of the air supply conduits causes liquid in the tank to flow upwardly through the lift tube and out of apertures in the upper portion thereof. Due to the unique properties of nuclear fuel dissolver solutions and the constraint placed on the amount of air that can be injected therein by conventional apparatus, there has been a need for a more effective means for agitating liquid in nuclear fuel digester tanks.

  11. Platelet preservation: agitation and containers.

    PubMed

    van der Meer, Pieter F; de Korte, Dirk

    2011-06-01

    For platelets to maintain their in vitro quality and in vivo effectiveness, they need to be stored at room temperature with gentle agitation in gas-permeable containers. The mode of agitation affects the quality of the platelets, and a gentle method of agitation, either a circular or a flat bed movement, provides the best results. Tumblers or elliptical agitators induce platelet activation and subsequent damage. As long as the platelets remain in suspension, the agitation speed is not important. Agitation of the platelet concentrates ensures that the platelets are continuously oxygenated, that sufficient oxygen can enter the storage container and that excess carbon dioxide can be expelled. During transportation of platelet concentrates, nowadays over long distances where they are held without controlled agitation, platelets may tolerate a certain period without agitation. However, evidence is accumulating that during the time without agitation, local hypoxia surrounding the platelets may induce irreversible harm to the platelets. Over the decades, more gas-permeable plastics have been used to manufacture platelet containers. The use of different plastics and their influence on the platelet quality both in vitro and in vivo is discussed. The improved gas-permeability has allowed the extension of platelet storage from 3 days in the early 1980s, to currently at least 7 days. In the light of new developments, particularly the introduction of pathogen reduction techniques, the use of platelet additive solutions and the availability of improved automated separators, further (renewed) research in this area is warranted.

  12. Cavitation-controlled ultrasonic agitator

    SciTech Connect

    Sheen, S.H.; Lawrence, W.P.; Raptis, A.C.

    1989-10-01

    High-intensity ultrasound generally produces nonlinear acoustic cavitation and streaming in liquids. The ultrasonic energy required to cause cavitation and streaming in a liquid depends on the physical properties of the liquid, e.g., surface tension, viscosity, and entrained gases. Both cavitation and streaming generate acoustic noise whose signatures may be used to distinguish the stage of agitation and thus allow the process to be controlled. An ultrasonic agitator has been designed for application in a confined area with a high-temperature, high-pressure, and corrosive environment. Control of this agitator is based on the detection of noise levels and subharmonics produced during cavitation and streaming. Noise signatures of agitation in different liquids and in liquids with particles have been determined, and discussed. 6 refs., 6 figs.

  13. Downhole gaseous liquid flow agitator

    SciTech Connect

    Kamilos, N.; Kennedy, D.D.; Lederhos, L.J. Jr.

    1989-03-14

    An apparatus is described for agitating and mixing of a gaseous phase and a liquid phase comprising: a first tube having non-blocking internal threads within the first tube to agitate a liquid phase adhering thereto with a gaseous phase passing therethrough, whereby a uniform gaseous phase and liquid phase mixture is formed; and a second tube connected to an end of the first tube having non-blocking internal threads of opposite handedness.

  14. Relaxing music at mealtime in nursing homes: effects on agitated patients with dementia.

    PubMed

    Hicks-Moore, Sandee Lynn

    2005-12-01

    Agitation in individuals with severe cognitive impairment is a significant problem that affects care and overall quality of life. Building on research conducted by Goddaer and Abraham (1994), this quasi-experimental study proposed that relaxing music played during meals would exert a calming effect and decrease agitated behaviors among nursing home residents with dementia. Thirty residents residing in a Special Care Unit participated in the 4-week study. The Cohen-Mansfield Agitation Inventory (Cohen-Mansfield, Marx, & Rosenthal, 1989) was used to gather data. Baseline data was obtained in Week 1 (no music). Music was introduced in Week 2, removed in Week 3, and reintroduced in Week 4. At the end of the 4-week study, overall reductions in the cumulative incidence of total agitated behaviors were observed. Reductions in absolute numbers of agitated behaviors were achieved during the weeks with music and a distinct pattern was observed.

  15. Treating agitation with dexmedetomidine in the ICU.

    PubMed

    Boyer, Jeanne

    2009-01-01

    Patients in the intensive care unit frequently experience delirium, anxiety, and agitation, with a variety of treatments used. This article discusses the role of an alpha-adrenoceptor agonist, dexmedetomidine, and its clinical relevance and advantages for the agitated patient.

  16. Agitation in DWPF Precipitate Pump Pit Tanks

    SciTech Connect

    Marek, J.C.

    1986-01-20

    An experimental program to test the reference agitator design for DWPF Precipitate Pump Pit Tanks has been completed. It was not known whether the reference agitator design would produce uniform mixing of precipitate slurry. There was also a concern that the reference agitator would produce excessive foaming of precipitate. An alternative agitator design that produces good mixing with little or no foam buildup was identified in the tests and is recommended for use in DWPF Precipitate Pump Pit Tanks. 7 refs.

  17. 7 CFR 58.417 - Mechanical agitators.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Mechanical agitators. 58.417 Section 58.417 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....417 Mechanical agitators. The mechanical agitators shall be of sanitary construction. The...

  18. 7 CFR 58.513 - Agitators.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Agitators. 58.513 Section 58.513 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....513 Agitators. Mechanical agitators shall meet the requirements of § 58.417....

  19. 7 CFR 58.513 - Agitators.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Agitators. 58.513 Section 58.513 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....513 Agitators. Mechanical agitators shall meet the requirements of § 58.417....

  20. 7 CFR 58.417 - Mechanical agitators.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Mechanical agitators. 58.417 Section 58.417 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....417 Mechanical agitators. The mechanical agitators shall be of sanitary construction. The...

  1. 7 CFR 58.513 - Agitators.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Agitators. 58.513 Section 58.513 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....513 Agitators. Mechanical agitators shall meet the requirements of § 58.417....

  2. 7 CFR 58.417 - Mechanical agitators.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Mechanical agitators. 58.417 Section 58.417 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....417 Mechanical agitators. The mechanical agitators shall be of sanitary construction. The...

  3. 7 CFR 58.513 - Agitators.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Agitators. 58.513 Section 58.513 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....513 Agitators. Mechanical agitators shall meet the requirements of § 58.417....

  4. 7 CFR 58.513 - Agitators.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Agitators. 58.513 Section 58.513 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....513 Agitators. Mechanical agitators shall meet the requirements of § 58.417....

  5. An investigation of long-term effects of group music therapy on agitation levels of people with Alzheimer's Disease.

    PubMed

    Ledger, Alison J; Baker, Felicity A

    2007-05-01

    This study aimed to investigate the long-term effects of group music therapy on agitation manifested by nursing home residents with Alzheimer's disease. A non-randomised experimental design was employed with one group receiving weekly music therapy (n = 26) and another group receiving standard nursing home care (n = 19). Agitation levels were measured five times over one year using the Cohen-Mansfield Agitation Inventory (Cohen-Mansfield, J. (1989). Agitation in the elderly. In N. Billig & P. V. Rabins (Eds.), Issues in geriatric psychiatry (pp. 101-113). Basel, Switzerland: Karger). Although music therapy participants showed short-term reductions in agitation, there were no significant differences between the groups in the range, frequency, and severity of agitated behaviours manifested over time. Multiple measures of treatment efficacy are necessary to better understand the long-term effects music therapy programs have on this population.

  6. Agitation

    MedlinePlus

    ... alertness (altered consciousness) can be a sign of delirium . Delirium has a medical cause and should be checked ... PCP, or opiates) Hospitalization (older adults often have delirium while in the hospital) Overactive thyroid gland ( hyperthyroidism ) ...

  7. Agitated Depression in Substance Dependence

    PubMed Central

    Leventhal, Adam M.; Gelernter, Joel; Oslin, David; Anton, Raymond F.; Farrer, Lindsay A.

    2011-01-01

    Background Depression with psychomotor agitation (PMA; “agitated depression”) is a putative psychiatric phenotype that appears to associate with some forms of substance dependence. However, it is unclear whether such relationships extend across different substances and independent (I-MDE) versus substance-induced (SI-MDE) subtypes of major depressive episodes. Method We examined whether lifetime depression with (vs. without) PMA was associated with lifetime substance dependence across individuals with lifetime: (1) I-MDE only (n = 575); and (2) SI-MDE only (n = 1683). Data were pooled from several family and genetic studies of substance dependence in which participants received identical structured interviews to diagnose DSM-IV mental disorders. Results In I-MDE, PMA was significantly associated with alcohol, cocaine, opioid, other drug (hallucinogen, inhalant, speed-ball), and sedative dependence. After controlling for demographic and clinical co-factors, PMA's relationship to dependence on opioids, other drugs, and sedatives remained significant, but not its relationship to alcohol or cocaine. In SI-MDE, PMA was significantly associated with alcohol, cocaine, opioid, and other drug dependence. After adjusting for co-factors, associations remained significant for dependence on cocaine and opioids, but not alcohol or other drugs. Relationships between PMA and opioid dependence were stronger in I-MDE than SI-MDE. Depression subtype (I-MDE vs. SI-MDE) did not moderate relations between PMA and non-opioid forms of substance dependence. Conclusions Agitated depression associates with certain forms of substance dependence, particularly opioid dependence. MDE subtype did not alter most PMA-dependence associations, which suggests that the mechanisms underlying this comorbidity are complex and potentially bidirectional. PMID:21277711

  8. A Controlled Agitation Process for Improving Quality of Canned Green Beans during Agitation Thermal Processing.

    PubMed

    Singh, Anika; Pratap Singh, Anubhav; Ramaswamy, Hosahalli S

    2016-06-01

    This work introduces the concept of a controlled agitation thermal process to reduce quality damage in liquid-particulate products during agitation thermal processing. Reciprocating agitation thermal processing (RA-TP) was used as the agitation thermal process. In order to reduce the impact of agitation, a new concept of "stopping agitations after sufficient development of cold-spot temperature" was proposed. Green beans were processed in No. 2 (307×409) cans filled with liquids of various consistency (0% to 2% CMC) at various frequencies (1 to 3 Hz) of RA-TP using a full-factorial design and heat penetration results were collected. Corresponding operator's process time to impart a 10-min process lethality (Fo ) and agitation time (AT) were calculated using heat penetration results. Accordingly, products were processed again by stopping agitations as per 3 agitation regimes, namely; full time agitation, equilibration time agitation, and partial time agitation. Processed products were photographed and tested for visual quality, color, texture, breakage of green beans, turbidity, and percentage of insoluble solids in can liquid. Results showed that stopping agitations after sufficient development of cold-spot temperatures is an effective way of reducing product damages caused by agitation (for example, breakage of beans and its leaching into liquid). Agitations till one-log temperature difference gave best color, texture and visual product quality for low-viscosity liquid-particulate mixture and extended agitations till equilibration time was best for high-viscosity products. Thus, it was shown that a controlled agitation thermal process is more effective in obtaining high product quality as compared to a regular agitation thermal process.

  9. Craniosacral still point technique: exploring its effects in individuals with dementia.

    PubMed

    Gerdner, Linda A; Hart, Laura K; Zimmerman, M Bridget

    2008-03-01

    A mixed methodology was used to explore the effects of craniosacral still point technique (CSPT) in 9 older adults with dementia. Participants were monitored at baseline (3 weeks), intervention (6 weeks), and postintervention (3 weeks) using the modified Cohen-Mansfield Agitation Inventory (M-CMAI). CSPT was implemented daily for 6 weeks by a certified craniosacral therapist. Findings indicated a statistically significant reduction in M-CMAI total and subscale scores during the intervention period. This reduction continued during postintervention for subscale scores of physical nonaggression and verbal agitation. Staff and family interviews provided convergent validity to the quantitative findings. Participants were also more cooperative during caregiving activities and displayed meaningful interactions.

  10. Particle Breakage in Agitated Dryers

    NASA Astrophysics Data System (ADS)

    Hare, Colin L.; Ghadiri, Mojtaba; Dennehy, Robert; Collier, Alan

    2009-06-01

    A method for predicting particle breakage in agitated dryers is described. The method utilizes an estimation of stresses and strains occurring in a dryer bed sheared by an impeller using the Distinct Element Method (DEM). An assemblage of particles is then subjected to these stresses in a shear cell to assess the extent of attrition under a range of stresses and strains. Paracetamol particles in the size range 500-600 μm are used for the experimental work. The relationship of attrition with stress and strain is then incorporated into the distribution of stress and strain in the dryer estimated by DEM. The extent of attrition for a range of conditions including the impeller speed has been analysed. The prediction shows impeller speed to have limited effect on attrition within the range of speeds tested.

  11. Emma Goldman: A Study in Female Agitation.

    ERIC Educational Resources Information Center

    Berry, Elizabeth

    The role of the agitator in society and the special characteristics of women agitators--in particular, Emma Goldman, an American anarchist from the early twentieth century--are discussed in this paper. Specific examples of the rhetoric used by Emma Goldman in her speeches (supporting anarchism, against women's suffrage, against abortion control,…

  12. Properly choose mechanical agitators for viscous liquids

    SciTech Connect

    Bakker, A.; Gates, L.E.

    1995-12-01

    High-viscosity mixing applications occur in most chemical process industries (CPI) plants. High-viscosity applications occur in the production of food, paint, drilling mud, and greases, to name a few. Mixing can occur in pipeline systems with motionless mixers, or in vessels using mechanical agitators, depending on the application and the process requirements. A wide variety of both motionless mixers and mechanical agitators is available to handle specific mixing problems and fluid types. This article gives an overview of designing the most commonly used agitator for blending applications: a top-entering agitator with a single shaft. The agitator can be equipped with multiple turbine-style impellers of different design, or with helical-ribbon or anchor-style impellers to optimize the agitator for the specific application and blending problem on hand. Although turbulent blending will be briefly discussed here also, this article will focus on blending in the laminar and transitional regimes. Also, the authors will discuss the special requirements for blending non-newtonian fluids, with and without yield stress. They first discuss the flow patterns and applicability of different impeller types and then present some design guidelines.

  13. Microbial Ecology in Anaerobic Digestion at Agitated and Non-Agitated Conditions

    PubMed Central

    Tian, Zhuoli; Cabrol, Léa; Ruiz-Filippi, Gonzalo; Pullammanappallil, Pratap

    2014-01-01

    To investigate the distribution and dynamics of microbial community in anaerobic digestion at agitated and non-agitated condition, 454 pyrosequencing of 16s rRNA was conducted. It revealed the distinct community compositions between the two digesters and their progressive shifting over time. Methanogens and syntrophic bacteria were found much less abundant in the agitated digester, which was mainly attributed to the presence of bacterial genera Acetanaerobacterium and Ruminococcus with relatively high abundance. The characterization of the microbial community corroborated the digestion performance affected at the agitated condition, where lower methane yield and delayed methane production rate were observed. This was further verified by the accumulation of propionic acid in the agitated digester. PMID:25313520

  14. Coal storage hopper with vibrating screen agitator

    SciTech Connect

    Daw, C.S.; Lackey, M.E.; Sy, R.L.

    1984-09-11

    The present invention is directed to a vibrating screen agitator in a coal storage hopper for assuring the uniform feed of coal having sufficient moisture content to effect agglomeration and bridging thereof in the coal hopper from the latter onto a conveyor mechanism. The vibrating screen agitator is provided by a plurality of transversely oriented and vertically spaced apart screens in the storage hopper with a plurality of vertically oriented rods attached to the screens. The rods are vibrated to effect the vibration of the screens and the breaking up of agglomerates in the coal which might impede the uniform flow of the coal from the hopper onto a conveyer.

  15. Coal storage hopper with vibrating screen agitator

    DOEpatents

    Daw, Charles S.; Lackey, Mack E.; Sy, Ronald L.

    1984-01-01

    The present invention is directed to a vibrating screen agitator in a coal storage hopper for assuring the uniform feed of coal having sufficient moisture content to effect agglomeration and bridging thereof in the coal hopper from the latter onto a conveyor mechanism. The vibrating screen agitator is provided by a plurality of transversely oriented and vertically spaced apart screens in the storage hopper with a plurality of vertically oriented rods attached to the screens. The rods are vibrated to effect the vibration of the screens and the breaking up of agglomerates in the coal which might impede the uniform flow of the coal from the hopper onto a conveyer.

  16. An Agitation Experiment with Multiple Aspects

    ERIC Educational Resources Information Center

    Spencer, Jordan L.

    2006-01-01

    This paper describes a multifaceted agitation and mixing experiment. The relatively inexpensive apparatus includes a variable-speed stirrer motor, two polycarbonate tanks, and an instrumented torque table. Students measure torque as a function of stirrer speed, and use conductive tracer data to estimate two parameters of a flow model. The effect…

  17. 82. VIEW OF AGITATORS FROM EAST. DRIVE AND STRUCTURAL SUPPORT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    82. VIEW OF AGITATORS FROM EAST. DRIVE AND STRUCTURAL SUPPORT OF AGITATOR No. 1 IN FOREGROUND. HORIZONTAL AIR LINE PARALLELS AGITATORS IN RIGHT HALF OF VIEW. - Bald Mountain Gold Mill, Nevada Gulch at head of False Bottom Creek, Lead, Lawrence County, SD

  18. 83. AGITATORS No. 2, No. 3, AND No. 4 FROM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    83. AGITATORS No. 2, No. 3, AND No. 4 FROM EAST. AIR SUPPLY RUNS THROUGH BENT BRACES ON RIGHT. NOTE AGITATOR RAKE LEANING AGAINST RETAINING WALL BETWEEN AGITATOR No. 2 AND No. 3. - Bald Mountain Gold Mill, Nevada Gulch at head of False Bottom Creek, Lead, Lawrence County, SD

  19. Advanced impeller geometry boosts liquid agitation

    SciTech Connect

    Fasano, J.B.; Bakker, A.; Penney, W.R. )

    1994-08-01

    A traditional agitator impeller often functions as a rather inefficient pump because of the way it produces fluid motion and pressure head. However, one can improve the amount of flow or shear generated by an impeller at constant power consumption and torque by changing its design. For example, a high-efficiency, axial-flow impeller produces more fluid motion per unit of power at constant torque than an otherwise similar pitched-blade turbine. The more-vigorous fluid motion cuts blend time and enhances heat-transfer in various flow-controlled mixing operations, such as blending of miscible fluids. For most applications, a higher degree of agitation intensity can be achieved on the same machine by substituting a high-efficiency impeller for a conventional pitched-blade unit. The high-efficiency impeller features a larger geometric pitch angle (30--60 deg) at the hub than at the tip (10--30 deg). Results from recently conducted controlled experiments indicate the beneficial effects of the high-efficiency impeller on blend time and heat-transfer coefficients in liquid-liquid mixing as well as solids suspension. This articles focuses on liquid agitation, with discussions of solids suspension set aside for a forthcoming piece in this series of articles on mixing.

  20. Emissions Inventory

    EPA Pesticide Factsheets

    This page describes the role of emission inventories in the air quality management process, a description of how emission inventories are developed, and where U.S. emission inventory information can be found.

  1. Fuel agitating device for internal combustion engine

    SciTech Connect

    Scouten, D.G.

    1992-09-22

    This patent describes an agitator for fuel being conducted to an internal combustion engine. It comprises: a casing, a chamber within the casing between the fuel inlet conduit and the fuel outlet conduit, flow divider means in the chamber for dividing the chamber into a plurality of fuel flow paths on opposite sides thereof, an inner wall in the casing defining the exit portion, flange means in the casing within the chamber and spaced radially inwardly from the inner wall, and conduit means within the flange means for conducting fuel to the outlet conduit.

  2. The Interactive Relationship between Pain, Psychosis, and Agitation in People with Dementia: Results from a Cluster-Randomised Clinical Trial

    PubMed Central

    Habiger, Torstein F.; Flo, Elisabeth; Achterberg, Wilco P.; Husebo, Bettina S.

    2016-01-01

    Background. Neuropsychiatric symptoms are common in people with dementia, and pain is thought to be an important underlying factor. Pain has previously been associated with agitation, and pain treatment has been shown to ameliorate agitated behaviour. So far, the association between pain and psychosis and the effect of pain treatment on psychotic symptoms is unclear. Furthermore, the impact of opioid treatment on psychosis is not established. Aim. To investigate the efficacy of a stepwise protocol for treating pain (SPTP) on psychosis and agitation measured with the Neuropsychiatric Inventory, Nursing Home version, and to explore the impact of opioid analgesics on psychosis. Method. Secondary analyses are from a cluster-randomised controlled trial including 352 patients with advanced dementia and agitation from 18 nursing homes in Western Norway. The intervention group received pain treatment according to SPTP. Results. Pain was associated with disinhibition (adjusted OR: 1.21, 95% CI: 1.10–1.34) and irritability (adjusted OR: 1.10, 95% CI: 1.01–1.21) at baseline. Pain treatment reduced agitation (p < 0.001, df = 1; 300) and aberrant motor behaviour (p = 0.017, df = 1; 300). Psychosis was reduced in people with at least one symptom at baseline (p = 0.034, df = 1; 135). The use of opioid analgesics did not increase psychotic symptoms. Study Registration. This trial is registered with ClinicalTrials.gov (NCT01021696), Norwegian Medicines Agency, EudraCT (EudraCTnr: 2008-007490-20). PMID:27247487

  3. Spontaneous knotting of an agitated string.

    PubMed

    Raymer, Dorian M; Smith, Douglas E

    2007-10-16

    It is well known that a jostled string tends to become knotted; yet the factors governing the "spontaneous" formation of various knots are unclear. We performed experiments in which a string was tumbled inside a box and found that complex knots often form within seconds. We used mathematical knot theory to analyze the knots. Above a critical string length, the probability P of knotting at first increased sharply with length but then saturated below 100%. This behavior differs from that of mathematical self-avoiding random walks, where P has been proven to approach 100%. Finite agitation time and jamming of the string due to its stiffness result in lower probability, but P approaches 100% with long, flexible strings. We analyzed the knots by calculating their Jones polynomials via computer analysis of digital photos of the string. Remarkably, almost all were identified as prime knots: 120 different types, having minimum crossing numbers up to 11, were observed in 3,415 trials. All prime knots with up to seven crossings were observed. The relative probability of forming a knot decreased exponentially with minimum crossing number and Möbius energy, mathematical measures of knot complexity. Based on the observation that long, stiff strings tend to form a coiled structure when confined, we propose a simple model to describe the knot formation based on random "braid moves" of the string end. Our model can qualitatively account for the observed distribution of knots and dependence on agitation time and string length.

  4. Finite element analysis of vessel nozzle for agitator supports

    SciTech Connect

    Wong, D.M.

    1996-12-01

    There are many industrial applications involving agitators/mixers supported by a vessel head and nozzle. The flow-induced agitator loads are often neglected or only partially considered in the vessel design stage. Inadequate supports reduce agitator drive operating life and in most cases promote vibration problems leading to fatigue failures. The vessel head and nozzle should be stiff enough to withstand the induced agitator loads. Some of the more significant design criteria are: (1) nozzle and head stiffness should be at least 1 million lb/in; (2) agitator shaft deflection should not be more than 1/32 inch per foot of shaft extension; (3) agitator support plane should not rotate more than 0.15 degree. This paper deals with a parametric finite element study of three tank sizes (4 ft., 8 ft. and 12 ft. diameter) to verify the validity and ease of compliance of these criteria in vessel design.

  5. Modelling gas exchange during platelet storage without agitation.

    PubMed

    Torres, R; Tormey, C A

    2016-11-01

    The aim of this study was to create a model of oxygen distribution within platelet storage bags to evaluate implications of reduced agitation approaches. Based on our model, platelet concentration and surface area most affect internal partial pressure of oxygen, while temperature modifications have least effect, indicating primary potential approaches for optimization of platelet storage with reduced or absent agitation.

  6. Effect of Preferred Music on Agitation After Traumatic Brain Injury.

    PubMed

    Park, Soohyun; Williams, Reg Arthur; Lee, Donghyun

    2016-04-01

    Agitation is a common behavioral problem after traumatic brain injury (TBI), which threatens the safety of patients and caregivers and disrupts the rehabilitation process. This study aimed to evaluate the effects of a preferred music intervention on the reduction of agitation in TBI patients and to compare the effects of preferred music with those of classical "relaxation" music. A single group, within-subjects, randomized crossover trial design was formed, consisting of 14 agitated patients with cognitive impairment after severe TBI. Patients listened to preferred music and classical "relaxation" music, with a wash-out period in between. Patients listening to the preferred music reported a significantly greater reduction in agitation compared with the effect seen during the classical "relaxation" music intervention (p = .046). These findings provide preliminary evidence that the preferred music intervention may be effective as an environmental therapeutic approach for reducing agitation after TBI.

  7. Effects of Tween 80 on cellulase stability under agitated conditions.

    PubMed

    Okino, Shohei; Ikeo, Makoto; Ueno, Yoshiki; Taneda, Daisuke

    2013-08-01

    The mechanism of the increase in the hydrolysis rate and yield by the addition of Tween 80 to the hydrolysis reaction of filter paper was investigated under static and agitated conditions. The increase in the hydrolysis rate by addition of Tween 80 was observed under the agitated condition only. The effects of Tween 80 on the changes in the protein concentration of individual cellulase components were investigated in the absence of substrates. Agitation of the enzyme solution resulted in the drastic decrease of SDS-PAGE bands intensity of CBH2 (cellobiohydrolase 2). The addition of Tween 80 prevented this. Thus, the Tween 80 functions to stabilize instable cellulase components under the agitated condition. Moreover, addition of Tween 80 completely suppressed the decrease of CBH2 intensity by agitation at 30°C. Results suggest that Tween 80 stabilizes instable cellulase components not only during hydrolysis, but during enzyme production also.

  8. Effects of individualized versus classical "relaxation" music on the frequency of agitation in elderly persons with Alzheimer's disease and related disorders.

    PubMed

    Gerdner, L A

    2000-03-01

    Confusion and agitation in elderly patients are crucial problems. This study tested Gerdner's mid-range theory of individualized music intervention for agitation. An experimental repeated measures pretest-posttest crossover design compared the immediate and residual effects of individualized music to classical "relaxation" music relative to baseline on the frequency of agitated behaviors in elderly persons with Alzheimer's disease and related disorders (ADRD). Thirty-nine subjects were recruited from six long-term-care facilities in Iowa. The sample consisted of 30 women and 9 men (mean age 82 years) with severe cognitive impairment. Baseline data were collected for 3 weeks. Findings from the Modified Hartsock Music Preference Questionnaire guided the selection of individualized music. Group A (n = 16) received individualized music for 6 weeks followed by a 2-week "washout" period and 6 weeks of classical "relaxation" music. Group B (n = 23) received the same protocol but in reverse order. Music interventions were presented for 30 minutes, two times per week. The Modified Cohen-Mansfield Agitation Inventory measured the dependent variable. A repeated measures analysis of variance with Bonferroni post hoc test showed a significant reduction in agitation during and following individualized music compared to classical music. This study expands science by testing and supporting a theoretically based intervention for agitation in persons with ADRD.

  9. Inventory Management

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Known as MRO for Maintenance, Repair and Operating supplies, Tropicana Products, Inc.'s automated inventory management system is an adaptation of the Shuttle Inventory Management System (SIMS) developed by NASA to assure adequate supply of every item used in support of the Space Shuttle. The Tropicana version monitors inventory control, purchasing receiving and departmental costs for eight major areas of the company's operation.

  10. Agitated Honeybees Exhibit Pessimistic Cognitive Biases

    PubMed Central

    Bateson, Melissa; Desire, Suzanne; Gartside, Sarah E.; Wright, Geraldine A.

    2011-01-01

    Summary Whether animals experience human-like emotions is controversial and of immense societal concern [1–3]. Because animals cannot provide subjective reports of how they feel, emotional state can only be inferred using physiological, cognitive, and behavioral measures [4–8]. In humans, negative feelings are reliably correlated with pessimistic cognitive biases, defined as the increased expectation of bad outcomes [9–11]. Recently, mammals [12–16] and birds [17–20] with poor welfare have also been found to display pessimistic-like decision making, but cognitive biases have not thus far been explored in invertebrates. Here, we ask whether honeybees display a pessimistic cognitive bias when they are subjected to an anxiety-like state induced by vigorous shaking designed to simulate a predatory attack. We show for the first time that agitated bees are more likely to classify ambiguous stimuli as predicting punishment. Shaken bees also have lower levels of hemolymph dopamine, octopamine, and serotonin. In demonstrating state-dependent modulation of categorization in bees, and thereby a cognitive component of emotion, we show that the bees' response to a negatively valenced event has more in common with that of vertebrates than previously thought. This finding reinforces the use of cognitive bias as a measure of negative emotional states across species and suggests that honeybees could be regarded as exhibiting emotions. Video Abstract PMID:21636277

  11. Nanocellulose Composite Materials Synthesizes with Ultrasonic Agitation

    NASA Astrophysics Data System (ADS)

    Kidd, Timothy; Folken, Andrew; Fritch, Byron; Bradley, Derek

    We have extended current techniques in forming nanocellulose composite solids, suspensions and aerogels to enhance the breakdown of cellulose into its molecular components. Using only mechanical processing which includes ball milling, using a simple mortar and pestle, and ultrasonic agitation, we are able to create very low concentration uniform nanocellulose suspensions in water, as well as incorporate other materials such as graphite, carbon nanotubes, and magnetic materials. Of interest is that no chemical processing is necessary, nor is the use of nanoparticles, necessary for composite formation. Using both graphite and carbon nanotubes, we are able to achieve conducting nanocellulose solids and aerogels. Standard magnetic powder can also be incorporated to create magnetic solids. The technique also allows for the creation of an extremely fine nanocellulose suspension in water. Using extremely low concentrations, less than 1% cellulose by mass, along with careful control over processing parameters, we are able to achieve highly dilute, yet homogenous nanocellulose suspensions. When air dried, these suspensions have similar hardness and strength properties to those created with more typical starting cellulose concentrations (2-10%). However, when freeze-dried, these dilute suspensions form aerogels with a new morphology with much higher surface area than those with higher starting concentrations. We are currently examining the effect of this higher surface area on the properties of nanocellulose aerogel composites and how it influences the impact of incorporating nanocellulose into other polymer materials.

  12. Risk factors for agitation in critically ill patients

    PubMed Central

    de Almeida, Thiago Miranda Lopes; de Azevedo, Luciano Cesar Pontes; Nosé, Paulo Maurício Garcia; de Freitas, Flavio Geraldo Resende; Machado, Flávia Ribeiro

    2016-01-01

    Objective To evaluate the incidence of agitation in the first 7 days after intensive care unit admission, its risk factors and its associations with clinical outcomes. Methods This single-center prospective cohort study included all patients older than 18 years with a predicted stay > 48 hours within the first 24 hours of intensive care unit admission. Agitation was defined as a Richmond Agitation Sedation Scale score ≥ +2, an episode of agitation or the use of a specific medication recorded in patient charts. Results Agitation occurred in 31.8% of the 113 patients. Multivariate analysis showed that delirium [OR = 24.14; CI95% 5.15 - 113.14; p < 0.001], moderate or severe pain [OR = 5.74; CI95% 1.73 - 19.10; p = 0.004], mechanical ventilation [OR = 10.14; CI95% 2.93 - 35.10; p < 0.001], and smoking habits [OR = 4.49; CI95% 1.33 - 15.17; p = 0.015] were independent factors for agitation, while hyperlactatemia was associated with a lower risk [OR = 0.169; CI95% 0.04 - 0.77; p = 0.021]. Agitated patients had fewer mechanical ventilation-free days at day 7 (p = 0.003). Conclusion The incidence of agitation in the first 7 days after admission to the intensive care unit was high. Delirium, moderate/severe pain, mechanical ventilation, and smoking habits were independent risk factors. Agitated patients had fewer ventilator-free days in the first 7 days. PMID:28099638

  13. 91. VIEW OF PORTLAND FILTER VACUUM RECEIVER FROM NORTHWEST. AGITATORS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    91. VIEW OF PORTLAND FILTER VACUUM RECEIVER FROM NORTHWEST. AGITATORS No. 4 AND No. 5 VISIBLE IN BACKGROUND. - Bald Mountain Gold Mill, Nevada Gulch at head of False Bottom Creek, Lead, Lawrence County, SD

  14. 84. AGITATORS No. 3, No. 4 AND No. 5 FROM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    84. AGITATORS No. 3, No. 4 AND No. 5 FROM SOUTHEAST. OLD PORTLAND FILTER FLOOR IS SEEN THROUGH FRAMING, LOWER RIGHT. - Bald Mountain Gold Mill, Nevada Gulch at head of False Bottom Creek, Lead, Lawrence County, SD

  15. 6. VIEW OF BRINING TANK Older, redwood model. Paddles agitated ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. VIEW OF BRINING TANK Older, redwood model. Paddles agitated the skins while they soaked in brine. The skins were then hung to dry. - Sealing Plant, St. George Island, Pribilof Islands, Saint George, Aleutians West Census Area, AK

  16. Hydrodynamic effects on cell growth in agitated microcarrier bioreactors

    NASA Technical Reports Server (NTRS)

    Cherry, Robert S.; Papoutsakis, E. Terry

    1988-01-01

    The net growth rate of bovine embryonic kidney cells in microcarrier bioreactor is the result of a variable death rate imposed on a cell culture trying to grow at a constant intrinsic growth rate. The death rate is a function of the agitation conditions in the system, and increases at higher agitation because of increasingly energetic interactions of the cell covered microcarriers with turbulent eddies in the fluid. At very low agitation rates bead-bead bridging becomes important; the large clumps formed by bridging can interact with larger eddies than single beads, leading to a higher death rate at low agitation. The growth and death rate were correlated with a dimensionless eddy number which compares eddy forces to the buoyant force on the bead.

  17. Design of agitation systems in Bingham slurries by pilot simulation

    SciTech Connect

    Nielsen, M.G.

    1987-01-01

    A method was required to determine the optimum agitator speed needed to produce overall motion of the Defense Waste Processing Facility (DWPF) high-level waste slurries in remote process cell vessels. Project schedule and limited process space required an accurate determination of agitator horsepower and size without the benefit of full-scale testing. The small scale testing of unique clear rheologically similar fluid is described along with tests and scale-up procedures. 2 refs., 3 figs.

  18. Agitator Mixing Analysis in a HB-Line Flat Tank

    SciTech Connect

    Lee, S.Y.

    2002-07-31

    In support of the HB-Line Engineering agitator mixing project, flow pattern calculations have been made for a 45 degrees pitched three-blade agitator submerged in a flat rectangular tank. The work is intended to determine agitator speeds that provide acceptable mixing performance for various tank liquid levels based on flow rates past solids deposited on the bottom surface of the flat tank. The modeling results will help ensure the acceptable suspension of solid particles as a function of agitator speed and tank liquid level during precipitation operations. The numerical modeling and calculations have been performed using a computational fluid dynamics approach. Three-dimensional steady-state momentum and continuity equations were used as the basic equations to estimate fluid motion driven by an agitator with three 45 degrees pitched blades. Hydraulic conditions were fully turbulent (Reynolds number about 2x104). A standard two-equation turbulence model (k-e), was used to capture turbulent eddy motion. The commercial finite volume code, Fluent [7], was used to create a prototypic geometry file with a non-orthogonal mesh. Hybrid meshing was used to fill the computational region between the round-edged tank bottom and agitator regions. At high rotational speeds and low tank levels, a surface vortex can reach the agitator blades and allow air to be drawn into the solid-fluid mixing zone. This is not desirable in terms of mixing performance. The analysis results show that the lowest liquid level among the four considered, 4.5 inches, is higher than the critical liquid height for air entrainment for agitator speeds up to 600 rpm. All the analysis results demonstrate that about 600 rpm provides adequate solids mixing capability for various tank levels (12, 8.5, 7, and 4.5 inches) containing 20-micron solids with a specific gravity of 2.5.

  19. Application of hydraulically assembled shaft coupling hubs to large agitators

    SciTech Connect

    Murray, W.E.; Anderson, T.D. ); Bethmann, H.K. )

    1991-01-01

    This paper describes the basis for and implementation of hydraulically assembled shaft coupling hubs for large tank-mounted agitators. This modification to the original design was intended to minimize maintenance personnel exposure to ionizing radiation and also provide for disassembly capability without damage to shafts or hubs. In addition to realizing these objectives, test confirmed that the modified couplings reduced agitator shaft end runouts approximately 65%, thereby reducing bearing loads and increasing service life, a significant enhancement for a nuclear facility. 5 refs.

  20. Application of hydraulically assembled shaft coupling hubs to large agitators

    SciTech Connect

    Murray, W.E.; Anderson, T.D.; Bethmann, H.K.

    1991-12-31

    This paper describes the basis for and implementation of hydraulically assembled shaft coupling hubs for large tank-mounted agitators. This modification to the original design was intended to minimize maintenance personnel exposure to ionizing radiation and also provide for disassembly capability without damage to shafts or hubs. In addition to realizing these objectives, test confirmed that the modified couplings reduced agitator shaft end runouts approximately 65%, thereby reducing bearing loads and increasing service life, a significant enhancement for a nuclear facility. 5 refs.

  1. Coal storage hopper with vibrating-screen agitator

    DOEpatents

    Daw, C.S.; Lackey, M.E.; Sy, R.L.

    1982-04-27

    The present invention is directed to a vibrating screen agitator in a coal storage hopper for assuring the uniform feed of coal having sufficient moisture content to effect agglomeration and bridging thereof in the coal hopper from the latter onto a conveyer mechanism. The vibrating scrren agitator is provided by a plurality of transversely oriented and vertically spaced apart screens in the storage hopper with a plurality of vertically oriented rods attached to the screens. The rods are vibrated to effect the vibration of the screens and the breaking up of agglomerates in the coal which might impede the uniform flow of the coal from the hopper onto a conveyer.

  2. Mechanisms of cell damage in agitated microcarrier tissue culture reactors

    NASA Technical Reports Server (NTRS)

    Cherry, Robert S.; Papoutsakis, E. Terry

    1986-01-01

    Cells growing on microcarriers may be damaged by collisions of the microcarrier against another microcarrier or the reactor agitator. Bead-bead collisions are caused by small-scale turbulence, which can also cause high local shear stress on the cells. The cells are also exposed to 10-20 Hz cyclic shear stress by bead rotation.

  3. Magnetic shaft seals prevent hazardous leakage from wastewater agitators

    SciTech Connect

    Traino, F.A.

    1985-11-01

    The US Department of Energy's laboratory in Miamisburg, OH, operated by Monsanto Research Corporation, processes approximately 45,000 gallons per week of low-level radioactive wastewater to meet Federal Environmental Protection Agency quality standards. Preventing the spread of radioactive contamination throughout the operating area demands effective sealing of all process piping, valves, pumps, and agitators. Rotating shafts of pumps and agitators installed a the start of operations in 1947 were sealed by stuffing glands with graphite impregnated asbestos packing. These pumps proved to be unsatisfactory. In the mid-1970's, new process pumps with mechanical seals and some with magnetic drives were installed. Later, in January 1979, new agitator shaft drives with double tandem, spring-loaded mechanical seals were installed, maintenance of these pumps was costly. The agitator drive shafts were redesigned to accommodate magnetic seals of the type successfully used in blowers and vacuum/pressure pumps in other plant locations. One inherent advantage of the magnetic seal is that it operates with a face loading as much as 50% less than a conventional spring-loaded mechanical seal. The lower loading by a predetermined uniform magnetic force contributes to long face life. Other advantages include compactness, ease of assembly with only a few parts, and insensitivity to vibration. The magnetic shaft seals installed on the agitator shafts in February 1983 are still in service without any leakage or need for maintenance. Based on current operating data and a projected five-year meantime between failures, the estimated cost benefit of the magnetic seals over spring-loaded mechanical seals over spring-loaded mechanical seals will be $640 vs $2400 respectively per seal, with 60% less downtime for maintenance.

  4. 40 CFR 63.169 - Standards: Pumps, valves, connectors, and agitators in heavy liquid service; instrumentation...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., and agitators in heavy liquid service; instrumentation systems; and pressure relief devices in liquid...: Pumps, valves, connectors, and agitators in heavy liquid service; instrumentation systems; and pressure relief devices in liquid service. (a) Pumps, valves, connectors, and agitators in heavy liquid...

  5. 40 CFR 63.169 - Standards: Pumps, valves, connectors, and agitators in heavy liquid service; instrumentation...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., and agitators in heavy liquid service; instrumentation systems; and pressure relief devices in liquid...: Pumps, valves, connectors, and agitators in heavy liquid service; instrumentation systems; and pressure relief devices in liquid service. (a) Pumps, valves, connectors, and agitators in heavy liquid...

  6. 40 CFR 63.169 - Standards: Pumps, valves, connectors, and agitators in heavy liquid service; instrumentation...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., and agitators in heavy liquid service; instrumentation systems; and pressure relief devices in liquid...: Pumps, valves, connectors, and agitators in heavy liquid service; instrumentation systems; and pressure relief devices in liquid service. (a) Pumps, valves, connectors, and agitators in heavy liquid...

  7. 40 CFR 63.169 - Standards: Pumps, valves, connectors, and agitators in heavy liquid service; instrumentation...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., and agitators in heavy liquid service; instrumentation systems; and pressure relief devices in liquid...: Pumps, valves, connectors, and agitators in heavy liquid service; instrumentation systems; and pressure relief devices in liquid service. (a) Pumps, valves, connectors, and agitators in heavy liquid...

  8. 40 CFR 63.169 - Standards: Pumps, valves, connectors, and agitators in heavy liquid service; instrumentation...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., and agitators in heavy liquid service; instrumentation systems; and pressure relief devices in liquid...: Pumps, valves, connectors, and agitators in heavy liquid service; instrumentation systems; and pressure relief devices in liquid service. (a) Pumps, valves, connectors, and agitators in heavy liquid...

  9. [Pain, agitation and delirium in acute respiratory failure].

    PubMed

    Funk, G-C

    2016-02-01

    Avoiding pain, agitation and delirium as well as avoiding unnecessary deep sedation is a powerful yet challenging strategy in critical care medicine. A number of interactions between cerebral function and respiratory function should be regarded in patients with respiratory failure and mechanical ventilation. A cooperative sedation strategy (i.e. patient is awake and free of pain and delirium) is feasible in many patients requiring invasive mechanical ventilation. Especially patients with mild acute respiratory distress syndrome (ARDS) seem to benefit from preserved spontaneous breathing. While completely disabling spontaneous ventilation with or without neuromuscular blockade is not a standard strategy in ARDS, it might be temporarily required in patients with severe ARDS, who have substantial dyssynchrony or persistent hypoxaemia. Since pain, agitation and delirium compromise respiratory function they should also be regarded during noninvasive ventilation and during ventilator weaning. Pharmacological sedation can have favourable effects in these situations, but should not be given routinely or uncritically.

  10. Ultrasonic agitation method for accelerating batch leaching tests

    SciTech Connect

    Caldwell, R.J.; Stegemann, J.A.; Chao, C.C.

    1996-12-31

    A method has been developed which uses ultrasonic cavitation to accelerate batch leaching tests. Batch leaching tests, in which attainment of an equilibrium between the solid sample and liquid leachant is desired, usually involve particle size reduction and mixing to hasten mass transfer of soluble compounds. In the study discussed here, mixing in the form of ultrasonic cavitation was used to supply an intense level of agitation. Breaking the liquid boundary layer surrounding individual waste particles ensured a maximum concentration gradient between the solid and liquid phases and accelerated attainment of steady state concentrations. Evaluation of the acceleration technique was made through comparison of leachate quality of stabilized/solidified (S/S) residue samples tested using the Wastewater Technology Centre`s (WTC) equilibrium extraction (EE) and an ultrasonically agitated version of the same test method (UEE). The sample preparation, liquid-to-solid ratio, extraction fluid, etc., specified in the EE method were held constant for the EE and UEE samples, while the duration and method of agitation was altered for the UEE samples. To date, this evaluation has been made using five metal finishing residues, which were selected based on their elevated concentrations of regulated contaminants. The results of the evaluations are presented and suggestions are made as to the applicability of this accelerated test method.

  11. Effect of agitation of EDTA with 808-nm diode laser on dentin microhardness.

    PubMed

    Arslan, Hakan; Yeter, Kübra Y; Karatas, Ertugrul; Yilmaz, Cenk B; Ayranci, Leyla B; Ozsu, Damla

    2015-02-01

    The aim of this study is to analyze the effect of agitation of ethylenediaminetetraacetic acid (EDTA) with diode laser at different agitation times on root dentin microhardness. Eighty-four specimens were divided randomly into seven groups, as follows: (1) distilled water, (2) 17% EDTA, (3) EDTA with 60 s ultrasonic agitation, (4) EDTA with 10 s laser agitation, (5) EDTA with 20 s laser agitation, (6) EDTA with 30 s laser agitation, and (7) EDTA with 40 s laser agitation. All of the specimens were irrigated with 5% NaOCl and distilled water except the distilled water group. Microhardness values were calculated before and after the procedures. Statistical analyses were performed using one-way ANOVA and Tukey post hoc tests. Statistically significant differences were determined between the distilled water and other groups. Also, statistically significant differences were observed between EDTA with 40 s laser agitation and EDTA, and EDTA with 10 and 20 s laser agitations. Ultrasonic agitation of EDTA affected microhardness of root dentin similar to EDTA (p > .05). All applications decreased the microhardness of root dentin when compared with distilled water. Agitation of EDTA with diode laser for 40 s caused more reduction in microhardness of root dentin when compared with EDTA.

  12. Citrus Inventory

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Florida's Charlotte County Property Appraiser is using an aerial color infrared mapping system for inventorying citrus trees for valuation purposes. The ACIR system has significantly reduced the time and manpower required for appraisal. Aerial photographs are taken and interpreted by a video system which makes it possible to detect changes from previous years. Potential problems can be identified. KSC's TU Office has awarded a contract to the Citrus Research and Education Center to adapt a prototype system which would automatically count trees and report totals.

  13. Flow-induced agitations create a granular fluid.

    PubMed

    Nichol, Kiri; Zanin, Alexey; Bastien, Renaud; Wandersman, Elie; van Hecke, Martin

    2010-02-19

    We fluidize a granular medium through localized stirring and probe the mechanical response of quiescent regions far away from the main flow. In these regions the material behaves like a liquid: high-density probes sink, low-density probes float at the depth given by Archimedes' law, and drag forces on moving probes scale linearly with the velocity. The fluidlike character of the material is set by agitations generated in the stirred region, suggesting a nonlocal rheology: the relation between applied stress and observed strain rate in one location depends on the strain rate in another location.

  14. Particulate contamination removal from wafers using plasmas and mechanical agitation

    DOEpatents

    Selwyn, G.S.

    1998-12-15

    Particulate contamination removal from wafers is disclosed using plasmas and mechanical agitation. The present invention includes the use of plasmas with mechanical agitation for removing particulate matter from the surface of a wafer. The apparatus hereof comprises a mechanical activator, at least one conducting contact pin for transferring the vibration from the activator to the wafer, clamp fingers that maintain the wafer`s position, and means for generating a plasma in the vicinity of the surface of the wafer, all parts of the cleaning apparatus except the mechanical activator and part of the contact pin being contained inside the processing chamber. By exposing a wafer to a plasma and providing motion thereto in a direction perpendicular to its surface, the bonding between the particulate matter and the surface may be overcome. Once free of the wafer surface, the particulates become charged by electrons from the plasma and are drawn into the plasma by attractive forces which keep them from redepositing. The introduction of a flowing gas through the plasma sweeps the particulates away from the wafer and out of the plasma. The entire surface is cleaned during one cleaning step. The use of an rf plasma to accomplish the particulate removal was found to remove more than 90% of the particulates. 4 figs.

  15. Particulate contamination removal from wafers using plasmas and mechanical agitation

    DOEpatents

    Selwyn, Gary S.

    1998-01-01

    Particulate contamination removal from wafers using plasmas and mechanical agitation. The present invention includes the use of plasmas with mechanical agitation for removing particulate matter from the surface of a wafer. The apparatus hereof comprises a mechanical activator, at least one conducting contact pin for transferring the vibration from the activator to the wafer, clamp fingers that maintain the wafer's position, and means for generating a plasma in the vicinity of the surface of the wafer, all parts of the cleaning apparatus except the mechanical activator and part of the contact pin being contained inside the processing chamber. By exposing a wafer to a plasma and providing motion thereto in a direction perpendicular to its surface, the bonding between the particulate matter and the surface may be overcome. Once free of the wafer surface, the particulates become charged by electrons from the plasma and are drawn into the plasma by attractive forces which keep them from redepositing. The introduction of a flowing gas through the plasma sweeps the particulates away from the wafer and out of the plasma. The entire surface is cleaned during one cleaning step. The use of an rf plasma to accomplish the particulate removal was found to remove more than 90% of the particulates.

  16. Effect of viscosity on the mixing efficiency in a self-agitation anaerobic baffled reactor.

    PubMed

    Qi, Wei-Kang; Guo, Yi-Ling; Xue, Mei; Du, Jing-Ru; Li, Weicheng; Li, Yu-You

    2015-05-01

    One special self-agitation reactor, which does not require a mechanical mixer or other equipment for mixing, has been introduced. Self-agitation is affected by variation in viscosity property. To obtain and research the effect of viscosity on mixing behavior in the self-agitation reactor, Fluent® was used to create numerical simulations and to visualize the fluid flow status. The results show that when the viscosity of the liquid is 1 mPa s, the entire self-agitation results in an almost completely mixed reactor. The substrate becomes difficult to agitate, and the diffusion of the substrate and the tracer become quite after every self-agitation, as the viscosity increases. Once the viscosity is higher than 25 mPa s, the substrate and tracer could not be mixed in the entire reactor, and the reactor is recognized as the combination of several completely mixed reactors between which little exchange of liquid occurs.

  17. State of Acute Agitation at Psychiatric Emergencies in Europe: The STAGE Study

    PubMed Central

    San, Luis; Marksteiner, Josef; Zwanzger, Peter; Figuero, María Aragüés; Romero, Francisco Toledo; Kyropoulos, Grigorios; Peixoto, Alberto Bessa; Chirita, Roxana; Boldeanu, Anca

    2016-01-01

    Background: Agitation is an array of syndromes and types of behaviors that are common in patients with psychiatric disorders. In Europe, the estimation of prevalence of agitation has been difficult due to the lack of standard studies or systematic data collection done on this syndrome. Objective: An observational, cross-sectional, multicenter study aimed to assess the prevalence of agitation episodes in psychiatric emergencies in different European countries. Method: For 1 week, all episodes of acute agitation that were attended to at the psychiatric emergency room (ER) or Acute Inpatient Unit (AIU) in the 27 participating centers were registered. The clinical characteristics and management of the agitation episode were also described. A descriptive analysis was performed. Results: A total of 334 agitation episodes out of 7295 psychiatric emergencies were recorded, giving a prevalence rate of 4.6% (95% CI: 4.12-5.08). Of them, 172 [9.4% (95% CI: 8.2-10.9)] were attended at the ER and 162 [2.8% (95% CI: 2.4-3.3)] at AIU. Only data from 165 episodes of agitation (those with a signed informed consent form) was registered and described in this report. The most common psychiatric conditions associated with agitation were schizophrenia, bipolar disorder and personality disorder. The management of agitation included from non-invasive to more coercive measures (mechanical, physical restraint or seclusion) that were unavoidable in more than half of the agitation episodes (59.5%). Conclusion: The results show that agitation is a common symptom in the clinical practice, both in emergency and inpatient psychiatric departments. Further studies are warranted to better recognize (using a standardized definition) and characterize agitation episodes. PMID:27857778

  18. Risk Factors of Emergence Agitation in Adults Undergoing General Anesthesia for Nasal Surgery

    PubMed Central

    Kim, Hyo-Jin; Kim, Hyo-Yeol; Kim, Jin-Kyoung; Choi, Seung-Won

    2015-01-01

    Objectives To identify the incidence and the risk factors of emergence agitation in adults undergoing general anesthesia for nasal surgery. Methods We retrospectively examined 792 patients aged ≥18 years who underwent general anesthesia for elective nasal surgery between July 2012 and August 2013. Patients in the postanesthesia care unit with a Richmond Agitation Sedation Scale≥+1 at any time were considered to have emergence agitation. Results The overall incidence of emergence agitation is 22.2%. From multivariate regression analysis, the following six variables were found to be significantly associated with emergence agitation (P<0.05): younger age, recent smoking, sevoflurane anesthesia, postoperative pain on the numerical rating scale (NRS)≥5, presence of a tracheal tube, and presence of a urinary catheter. Presence of a tracheal tube was the greatest risk factor, increasing the risk of developing emergence agitation by approximately fivefold (odds ratio, 5.448; 95% confidence interval, 2.973 to 9.982). Younger age was also a strong risk factor (odds ratio, 0.975 for each 1-year increase; 95% confidence interval, 0.964 to 0.987). Current smoking, sevoflurane anesthesia, postoperative pain of NRS≥5, and the presence of a urinary catheter nearly doubled the risk of emergence agitation. Conclusion Emergence agitation following general anesthesia is a common complication in adult nasal surgery patients. To reduce the occurrence and consequences of agitation episodes, elimination of the associated risk factors is necessary, especially in at-risk patients. PMID:25729495

  19. Comparing the Effects of Multisensory Stimulation and Individualized Music Sessions on Elderly People with Severe Dementia: A Randomized Controlled Trial.

    PubMed

    Sánchez, Alba; Maseda, Ana; Marante-Moar, M Pilar; de Labra, Carmen; Lorenzo-López, Laura; Millán-Calenti, José Carlos

    2016-03-08

    The objective of this study was to compare the effects of a multisensory stimulation environment (MSSE) and individualized music sessions on agitation, emotional and cognitive status, and dementia severity in a sample of institutionalized patients with severe dementia. Twenty-two participants with a diagnosis of severe or very severe dementia were randomly assigned to two groups: MSSE and individualized music sessions. Both groups participated in two 30-min weekly sessions over 16 weeks. Outcomes were agitation (Cohen-Mansfield Agitation Inventory, CMAI), mood (Cornell Scale for Depression in Dementia, CSDD), anxiety (Rating Anxiety in Dementia, RAID), cognitive function (Severe Mini-Mental State Examination, SMMSE), and the overall severity of dementia (Bedford Alzheimer Nursing Severity Scale, BANS-S). They were assessed at baseline (pre-trial), in the middle (mid-trial), at the end of the intervention (post-trial), and 8 weeks after the intervention (follow-up). Patients in the MSSE group showed significant improvement in their RAID and BANS-S scores compared with the individualized music group post- versus pre-trial. With regard to agitation, there was improvement during the intervention in both the MSSE and individualized music groups in the CMAI total score after 16 weeks of intervention, with no significant differences between the groups. The results suggest that MSSE could have better effects on anxiety symptoms and dementia severity in comparison with individualized music sessions in elderly patients with severe dementia.

  20. Improved performance in viscous mycelial fermentations by agitator retrofitting.

    PubMed

    Buckland, B C; Gbewonyo, K; Dimasi, D; Hunt, G; Westerfield, G; Nienow, A W

    1988-05-01

    For viscous mycelial fermentations it was demonstrated at the pilot-plant scale that the replacement of standard radial flow Rushton turbines with larger diameter axial-flow Prochem hydrofoil impellers significantly improved oxygen transfer efficiency. It was also determined that the Streptomyces broth under evaluation is highly shear thinning. Separate experiments using a Norcardia broth with similar Theological properties demonstrated that the oxygen transfer coefficient, K(L)a, can be greatly increased by use of water additions to reduce broth viscosity. These observations are consistent with the hypothesis that the improvement in oxygen transfer by changing agitator types is primarily due to an improvement in bulk mixing. A model is presented, based on the concepts of Bajpai and Reuss, which explains this improvement in performance in terms of enlargement of the well mixed micromixer region for viscous mycelial broths.

  1. Symptoms of agitated depression and/or akathisia.

    PubMed

    Peitl, Marija Vučić; Prološčić, Joško; Blažević-Zelić, Sandra; Skarpa-Usmiani, Ivona; Peitl, Vjekoslav

    2011-03-01

    Akathisia is a syndrome characterized by the unpleasant sensation of "inner" restlessness that manifests itself in the inability of sitting still or not moving. Many types of medicaments can cause akathisia as an adverse event of their use and they include: antipsychotics, antidepressants, antiemetics, antihistamines, and psychoactive substances. We will present the case of a 50 year old patient, treated on two occasions for psychotic depression. During the second hospitalization it is possible that antipsychotic treatment combined with an antidepressant caused akathisia or there were symptoms of agitated depression and akathisia present at the same time, which is very difficult to determine in everyday clinical practice. We can conclude that in this case, as in many others, akathisia as a possible adverse effect of psychopharmacs was very hard to identify. Therefore, it is necessary to have akathisia in mind when using certain medicaments, especially when combining several that use the same enzymatic system and consequently raise levels of at least one of them.

  2. Hydrodynamic effects on cells in agitated tissue culture reactors

    NASA Technical Reports Server (NTRS)

    Cherry, R. S.; Papoutsakis, E. T.

    1986-01-01

    The mechanisms by which hydrodynamic forces can affect cells grown on microcarrier beads in agitated cell culture reactors were investigated by analyzing the motion of microcarriers relative to the surrounding fluid, to each other, and to moving or stationary solid surfaces. It was found that harmful effects on cell cultures that have been previously attributed to shear can be better explained as the effects of turbulence (of a size scale comparable to the microcarriers or the spacing between them) or collisions. The primary mechanisms of cell damage involve direct interaction between microcarriers and turbulent eddies, collisions between microcarriers in turbulent flow, and collisions against the impeller or other solid surfaces. The implications of these analytical results for the design of tissue culture reactors are discussed.

  3. A Longitudinal Examination of Agitation and Resident Characteristics in the Nursing Home

    ERIC Educational Resources Information Center

    Burgio, Louis D.; Park, Nan Sook; Hardin, J. Michael; Sun, Fei

    2007-01-01

    Purpose: Agitation frequently accompanies cognitive decline among nursing home residents. This study used cross-sectional and longitudinal (up to 18 months) methods to examine agitation among profoundly and moderately impaired residents using both staff report and direct observation methods. Design and Methods: The study included participants (N =…

  4. The Relationship between Agitated Behavior and Cognitive Functioning in Nursing Home Residents: Preliminary Results.

    ERIC Educational Resources Information Center

    Cohen-Mansfield, Jiska

    Agitation is a significant problem for nursing home residents, their families, and their caretakers. Agitation is defined as inappropriate verbal, vocal, or motor activity which is not explained by needs or confusion per se. It includes behaviors such as aimless wandering, pacing, cursing, screaming, biting, and fighting. The inappropriate nature…

  5. Behavioral Characteristics of Agitated Nursing Home Residents with Dementia at the End of Life

    ERIC Educational Resources Information Center

    Allen, Rebecca S.; Burgio, Louis D.; Fisher, Susan E.; Hardin, J. Michael; Shuster, John L., Jr.

    2005-01-01

    Purpose: The purpose of this study was to examine group differences in verbal agitation, verbal interaction, bed restraint, pain, analgesic and neuroleptic medication use, and medical comorbidity among agitated nursing home residents who died during a 6-month clinical trial compared with residents of the same gender and similar initial cognitive…

  6. System for agitating the acid in a lead-acid battery

    DOEpatents

    Weintraub, Alvin; MacCormack, Robert S.

    1987-01-01

    A system and method for agitating the acid in a large lead-sulfuric acid storage battery of the calcium type. An air-lift is utilized to provide the agitation. The air fed to the air-lift is humidified prior to being delivered to the air-lift.

  7. [Application of music therapy for managing agitated behavior in older people with dementia].

    PubMed

    Sung, Huei-Chuan; Chang, Anne M; Abbey, Jennifer

    2006-10-01

    Older people with dementia may display negative emotions, memory problems, sleep disturbance, and agitated behavior. Among these symptoms, agitated behavior has been identified by families and nursing staff as the care problem that presents the greatest challenge. Several studies have found that music therapy reduced agitated behaviors in those with dementia and recommended use of music as an effective strategy in managing this behavioral problem. Music therapy represents a lower cost, effective care approach that nursing staff can easily learn and apply to those with dementia. Furthermore, reductions in agitated behavior in dementia patients that result from music therapy can also alleviate caregiver stress and burden of care, leading to improvements in the health and quality of life of both dementia patients and their caregivers. This paper aims to introduce the principles and application of music therapy in the management of agitated behavior in those with dementia.

  8. Quetiapine reduces irritability and risk of suicide in patients with agitated depression.

    PubMed

    Nishiyama, Akiyoshi; Matsumoto, Hideo

    2013-07-20

    Patients who suffer from agitated depression accompanied by psychomotor agitation and irritability are prone to suicidal ideation and attempts and must therefore be diagnosed and treated with utmost care. Clinically, there have been more than a few cases of suicidal attempts that seemed to have been provoked by careless prescription of antidepressant medication. In the present study, administration of quetiapine to 3 patients in the acute phase of agitated depression resulted in rapid improvement in irritability and alleviation of depression. Depression in these 3 patients was caused by chronic (persistent) anxiety and tension. During the acute phase, the patients evidenced psychomotor agitation and irritability, often experiencing a sudden, overwhelming urge to commit suicide. Findings from the present study suggest that treatment with quetiapine in patients with this type of agitated depression can quickly alleviate symptoms of anxiety and irritability and reduce the risk of suicide.

  9. Do sound levels and space contribute to agitation in nursing home residents with dementia?

    PubMed

    Joosse, Laura L

    2012-07-01

    Individuals with dementia living in nursing homes may be exposed to non-therapeutic levels of sound. There is insufficient research examining the relationship between sound levels, personal space, and agitation in people with dementia. Using an observational designed study, 53 participants from four southeastern Wisconsin nursing homes were observed; data on sound levels, space, and agitation levels were obtained. Sound was a significant predictor of agitation. The accumulation of sound predicted agitated behavior and explained 16% of the variance, F(5, 47) = 4.520, p < 0.002, and adjusted R(2) = 0.253. The findings suggest agitation may be a clue that sound in the environment is causing stress for residents with dementia.

  10. Micro acoustic resonant chambers for heating/agitating/mixing (MARCHAM)

    NASA Astrophysics Data System (ADS)

    Sherrit, Stewart; Noell, Aaron C.; Fisher, Anita M.; Takano, Nobuyuki; Grunthaner, Frank

    2016-04-01

    A variety of applications require the mixing and/or heating of a slurry made from a powder/fluid mixture. One of these applications, Sub Critical Water Extraction (SCWE), is a process where water and an environmental powder sample (sieved soil, drill cuttings, etc.) are heated in a sealed chamber to temperatures greater than 200 degrees Celsius by allowing the pressure to increase, but without reaching the critical point of water. At these temperatures, the ability of water to extract organics from solid particulate increases drastically. This paper describes the modeling and experimentation on the use of an acoustic resonant chamber which is part of an amino acid detection instrument called Astrobionibbler [Noell et al. 2014, 2015]. In this instrument we use acoustics to excite a fluid- solid fines mixture in different frequency/amplitude regimes to accomplish a variety of sample processing tasks. Driving the acoustic resonant chamber at lower frequencies can create circulation patterns in the fluid and mixes the liquid and fines, while driving the chamber at higher frequencies one can agitate the fluid and powder and create a suspension. If one then drives the chamber at high amplitude at resonance heating of the slurry occurs. In the mixing and agitating cell the particle levitation force depends on the relative densities and compressibility's of the particulate and fluid and on the kinetic and potential energy densities associated with the velocity and pressure fields [Glynne-Jones, Boltryk and Hill 2012] in the cell. When heating, the piezoelectric transducer and chamber is driven at high power in resonance where the solid/fines region is modelled as an acoustic transmission line with a large loss component. In this regime, heat is pumped into the solution/fines mixture and rapidly heats the sample. We have modeled the piezoelectric transducer/chamber/ sample using Mason's equivalent circuit. In order to assess the validity of the model we have built and

  11. Agitation in nursing home residents: the role of gender and social context.

    PubMed

    Burgio, L D; Butler, F R; Roth, D L; Hardin, J M; Hsu, C C; Ung, K

    2000-12-01

    We investigated the relationship among gender of resident, staff social interaction, and agitation in 46 (31 male and 15 female) nursing home residents with clinically significant agitation. Direct observations were conducted of resident behaviors and environmental contextual events using a computer-assisted, real-time observational system. The system recorded frequency, duration, and temporal sequencing of events. Results show that female residents displayed almost three times the amount of agitation as male residents (35% vs. 13% of total observation time, respectively), although men in the study were more likely to receive psychoactive drugs for their agitation. Staff spent similar amounts of time verbally interacting and touching male and female residents. Sequential analyses were conducted to examine the likelihood of staff verbal and touch interactions both preceding and following resident agitation using Bakeman and Quera's (1995) SDIS-GSEQ program. Results suggest that staff touch and verbal interaction elicit agitation in a significant proportion of residents. Once agitation occurs, staff were likely to respond by interacting verbally, but not physically, with the resident.

  12. Managing Agitation Associated with Schizophrenia and Bipolar Disorder in the Emergency Setting

    PubMed Central

    Zeller, Scott L.; Citrome, Leslie

    2016-01-01

    Introduction Patient agitation represents a significant challenge in the emergency department (ED), a setting in which medical staff are working under pressure dealing with a diverse range of medical emergencies. The potential for escalation into aggressive behavior, putting patients, staff, and others at risk, makes it imperative to address agitated behavior rapidly and efficiently. Time constraints and limited access to specialist psychiatric support have in the past led to the strategy of “restrain and sedate,” which was believed to represent the optimal approach; however, it is increasingly recognized that more patient-centered approaches result in improved outcomes. The objective of this review is to raise awareness of best practices for the management of agitation in the ED and to consider the role of new pharmacologic interventions in this setting. Discussion The Best practices in Evaluation and Treatment of Agitation (BETA) guidelines address the complete management of agitation, including triage, diagnosis, interpersonal calming skills, and medicine choices. Since their publication in 2012, there have been further developments in pharmacologic approaches for dealing with agitation, including both new agents and new modes of delivery, which increase the options available for both patients and physicians. Newer modes of delivery that could be useful in rapidly managing agitation include inhaled, buccal/sublingual and intranasal formulations. To date, the only formulation administered via a non-intramuscular route with a specific indication for agitation associated with bipolar or schizophrenia is inhaled loxapine. Non-invasive formulations, although requiring cooperation from patients, have the potential to improve overall patient experience, thereby improving future cooperation between patients and healthcare providers. Conclusion Management of agitation in the ED should encompass a patient-centered approach, incorporating non-pharmacologic approaches

  13. Effects of ultrasonic agitation on adhesion strength of micro electroforming Ni layer on Cu substrate.

    PubMed

    Zhao, Zhong; Du, Liqun; Xu, Zheng; Shao, Ligeng

    2016-03-01

    Micro electroforming is an important technology, which is widely used for fabricating micro metal devices in MEMS. The micro metal devices have the problem of poor adhesion strength, which has dramatically influenced the dimensional accuracy of the devices and seriously limited the development of the micro electroforming technology. In order to improve the adhesion strength, ultrasonic agitation method is applied during the micro electroforming process in this paper. To explore the effect of the ultrasonic agitation, micro electroforming experiments were carried out under ultrasonic and ultrasonic-free conditions. The effects of the ultrasonic agitation on the micro electroforming process were investigated by polarization and alternating current (a.c.) impedance methods. The real surface area of the electroforming layer was measured by cyclic voltammetry method. The compressive stress and the crystallite size of the electroforming layer were measured by X-ray Diffraction (XRD) method. The adhesion strength of the electroforming layer was measured by scratch test. The experimental results show that the imposition of the ultrasonic agitation decreases the polarization overpotential and increases the charge transfer process at the electrode-electrolyte interface during the electroforming process. The ultrasonic agitation increases the crystallite size and the real surface area, and reduces the compressive stress. Then the adhesion strength is improved about 47% by the ultrasonic agitation in average. In addition, mechanisms of the ultrasonic agitation improving the adhesion strength are originally explored in this paper. The mechanisms are that the ultrasonic agitation increases the crystallite size, which reduces the compressive stress. The lower the compressive stress is, the larger the adhesion strength is. Furthermore, the ultrasonic agitation increases the real surface area, enhances the mechanical interlocking strength and consequently increases the adhesion

  14. Optimal nonpharmacological management of agitation in Alzheimer's disease: challenges and solutions.

    PubMed

    Millán-Calenti, José Carlos; Lorenzo-López, Laura; Alonso-Búa, Begoña; de Labra, Carmen; González-Abraldes, Isabel; Maseda, Ana

    2016-01-01

    Many patients with Alzheimer's disease will develop agitation at later stages of the disease, which constitutes one of the most challenging and distressing aspects of dementia. Recently, nonpharmacological therapies have become increasingly popular and have been proven to be effective in managing the behavioral symptoms (including agitation) that are common in the middle or later stages of dementia. These therapies seem to be a good alternative to pharmacological treatment to avoid unpleasant side effects. We present a systematic review of randomized controlled trials (RCTs) focused on the nonpharmacological management of agitation in Alzheimer's disease (AD) patients aged 65 years and above. Of the 754 studies found, eight met the inclusion criteria. This review suggests that music therapy is optimal for the management of agitation in institutionalized patients with moderately severe and severe AD, particularly when the intervention includes individualized and interactive music. Bright light therapy has little and possibly no clinically significant effects with respect to observational ratings of agitation but decreases caregiver ratings of physical and verbal agitation. Therapeutic touch is effective for reducing physical nonaggressive behaviors but is not superior to simulated therapeutic touch or usual care for reducing physically aggressive and verbally agitated behaviors. Melissa oil aromatherapy and behavioral management techniques are not superior to placebo or pharmacological therapies for managing agitation in AD. Further research in clinical trials is required to confirm the effectiveness and long-term effects of nonpharmacological interventions for managing agitation in AD. These types of studies may lead to the development of future intervention protocols to improve the well-being and daily functioning of these patients, thereby avoiding residential care placement.

  15. Optimal nonpharmacological management of agitation in Alzheimer’s disease: challenges and solutions

    PubMed Central

    Millán-Calenti, José Carlos; Lorenzo-López, Laura; Alonso-Búa, Begoña; de Labra, Carmen; González-Abraldes, Isabel; Maseda, Ana

    2016-01-01

    Many patients with Alzheimer’s disease will develop agitation at later stages of the disease, which constitutes one of the most challenging and distressing aspects of dementia. Recently, nonpharmacological therapies have become increasingly popular and have been proven to be effective in managing the behavioral symptoms (including agitation) that are common in the middle or later stages of dementia. These therapies seem to be a good alternative to pharmacological treatment to avoid unpleasant side effects. We present a systematic review of randomized controlled trials (RCTs) focused on the nonpharmacological management of agitation in Alzheimer’s disease (AD) patients aged 65 years and above. Of the 754 studies found, eight met the inclusion criteria. This review suggests that music therapy is optimal for the management of agitation in institutionalized patients with moderately severe and severe AD, particularly when the intervention includes individualized and interactive music. Bright light therapy has little and possibly no clinically significant effects with respect to observational ratings of agitation but decreases caregiver ratings of physical and verbal agitation. Therapeutic touch is effective for reducing physical nonaggressive behaviors but is not superior to simulated therapeutic touch or usual care for reducing physically aggressive and verbally agitated behaviors. Melissa oil aromatherapy and behavioral management techniques are not superior to placebo or pharmacological therapies for managing agitation in AD. Further research in clinical trials is required to confirm the effectiveness and long-term effects of nonpharmacological interventions for managing agitation in AD. These types of studies may lead to the development of future intervention protocols to improve the well-being and daily functioning of these patients, thereby avoiding residential care placement. PMID:26955265

  16. 40 CFR 63.1010 - Pumps, valves, connectors, and agitators in heavy liquid service; pressure relief devices in...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... agitators in heavy liquid service; pressure relief devices in liquid service; and instrumentation systems..., connectors, and agitators in heavy liquid service; pressure relief devices in liquid service; and... comply with paragraphs (b)(1) and (b)(2) of this section. Pumps, valves, connectors, and agitators...

  17. 40 CFR 63.1009 - Agitators in gas and vapor service and in light liquid service standards.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 11 2012-07-01 2012-07-01 false Agitators in gas and vapor service and... § 63.1009 Agitators in gas and vapor service and in light liquid service standards. (a) Compliance... in the referencing subpart. (b) Leak detection—(1) Monitoring method. Each agitator seal shall...

  18. 40 CFR 63.1009 - Agitators in gas and vapor service and in light liquid service standards.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 11 2014-07-01 2014-07-01 false Agitators in gas and vapor service and... § 63.1009 Agitators in gas and vapor service and in light liquid service standards. (a) Compliance... in the referencing subpart. (b) Leak detection—(1) Monitoring method. Each agitator seal shall...

  19. 40 CFR 63.1028 - Agitators in gas and vapor service and in light liquid service standards.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 10 2011-07-01 2011-07-01 false Agitators in gas and vapor service and... Standards § 63.1028 Agitators in gas and vapor service and in light liquid service standards. (a) Compliance... in the referencing subpart. (b) (c) Leak detection—(1) Monitoring method. Each agitator seal shall...

  20. 40 CFR 65.110 - Standards: Pumps, valves, connectors, and agitators in heavy liquid service; pressure relief...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., and agitators in heavy liquid service; pressure relief devices in liquid service; and instrumentation..., connectors, and agitators in heavy liquid service; pressure relief devices in liquid service; and..., valves, connectors, and agitators in heavy liquid service; pressure relief devices in light liquid...

  1. 40 CFR 65.109 - Standards: Agitators in gas/vapor service and in light liquid service.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 15 2011-07-01 2011-07-01 false Standards: Agitators in gas/vapor... Standards: Agitators in gas/vapor service and in light liquid service. (a) Compliance schedule. The owner or...) Leak detection—(1) Monitoring method. Each agitator seal shall be monitored monthly to detect leaks...

  2. 40 CFR 65.109 - Standards: Agitators in gas/vapor service and in light liquid service.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 16 2014-07-01 2014-07-01 false Standards: Agitators in gas/vapor... Standards: Agitators in gas/vapor service and in light liquid service. (a) Compliance schedule. The owner or...) Leak detection—(1) Monitoring method. Each agitator seal shall be monitored monthly to detect leaks...

  3. 40 CFR 65.110 - Standards: Pumps, valves, connectors, and agitators in heavy liquid service; pressure relief...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., and agitators in heavy liquid service; pressure relief devices in liquid service; and instrumentation..., connectors, and agitators in heavy liquid service; pressure relief devices in liquid service; and..., valves, connectors, and agitators in heavy liquid service; pressure relief devices in light liquid...

  4. 40 CFR 63.1009 - Agitators in gas and vapor service and in light liquid service standards.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 11 2013-07-01 2013-07-01 false Agitators in gas and vapor service and... § 63.1009 Agitators in gas and vapor service and in light liquid service standards. (a) Compliance... in the referencing subpart. (b) Leak detection—(1) Monitoring method. Each agitator seal shall...

  5. 40 CFR 65.110 - Standards: Pumps, valves, connectors, and agitators in heavy liquid service; pressure relief...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., and agitators in heavy liquid service; pressure relief devices in liquid service; and instrumentation..., connectors, and agitators in heavy liquid service; pressure relief devices in liquid service; and..., valves, connectors, and agitators in heavy liquid service; pressure relief devices in light liquid...

  6. 40 CFR 63.1010 - Pumps, valves, connectors, and agitators in heavy liquid service; pressure relief devices in...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... agitators in heavy liquid service; pressure relief devices in liquid service; and instrumentation systems..., connectors, and agitators in heavy liquid service; pressure relief devices in liquid service; and... comply with paragraphs (b)(1) and (b)(2) of this section. Pumps, valves, connectors, and agitators...

  7. 40 CFR 65.109 - Standards: Agitators in gas/vapor service and in light liquid service.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 16 2013-07-01 2013-07-01 false Standards: Agitators in gas/vapor... Standards: Agitators in gas/vapor service and in light liquid service. (a) Compliance schedule. The owner or...) Leak detection—(1) Monitoring method. Each agitator seal shall be monitored monthly to detect leaks...

  8. 40 CFR 65.110 - Standards: Pumps, valves, connectors, and agitators in heavy liquid service; pressure relief...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., and agitators in heavy liquid service; pressure relief devices in liquid service; and instrumentation..., connectors, and agitators in heavy liquid service; pressure relief devices in liquid service; and..., valves, connectors, and agitators in heavy liquid service; pressure relief devices in light liquid...

  9. 40 CFR 63.1028 - Agitators in gas and vapor service and in light liquid service standards.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 11 2013-07-01 2013-07-01 false Agitators in gas and vapor service and... Standards § 63.1028 Agitators in gas and vapor service and in light liquid service standards. (a) Compliance... in the referencing subpart. (b) (c) Leak detection—(1) Monitoring method. Each agitator seal shall...

  10. 40 CFR 63.173 - Standards: Agitators in gas/vapor service and in light liquid service.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 10 2013-07-01 2013-07-01 false Standards: Agitators in gas/vapor... Equipment Leaks § 63.173 Standards: Agitators in gas/vapor service and in light liquid service. (a)(1) Each agitator shall be monitored monthly to detect leaks by the methods specified in § 63.180(b) of this...

  11. 40 CFR 63.1028 - Agitators in gas and vapor service and in light liquid service standards.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 11 2012-07-01 2012-07-01 false Agitators in gas and vapor service and... Standards § 63.1028 Agitators in gas and vapor service and in light liquid service standards. (a) Compliance... in the referencing subpart. (b) (c) Leak detection—(1) Monitoring method. Each agitator seal shall...

  12. 40 CFR 63.1028 - Agitators in gas and vapor service and in light liquid service standards.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 11 2014-07-01 2014-07-01 false Agitators in gas and vapor service and... Standards § 63.1028 Agitators in gas and vapor service and in light liquid service standards. (a) Compliance... in the referencing subpart. (b) (c) Leak detection—(1) Monitoring method. Each agitator seal shall...

  13. 40 CFR 63.1009 - Agitators in gas and vapor service and in light liquid service standards.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 10 2011-07-01 2011-07-01 false Agitators in gas and vapor service and... § 63.1009 Agitators in gas and vapor service and in light liquid service standards. (a) Compliance... in the referencing subpart. (b) Leak detection—(1) Monitoring method. Each agitator seal shall...

  14. 40 CFR 63.1010 - Pumps, valves, connectors, and agitators in heavy liquid service; pressure relief devices in...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... agitators in heavy liquid service; pressure relief devices in liquid service; and instrumentation systems..., connectors, and agitators in heavy liquid service; pressure relief devices in liquid service; and... comply with paragraphs (b)(1) and (b)(2) of this section. Pumps, valves, connectors, and agitators...

  15. 40 CFR 65.110 - Standards: Pumps, valves, connectors, and agitators in heavy liquid service; pressure relief...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., and agitators in heavy liquid service; pressure relief devices in liquid service; and instrumentation..., connectors, and agitators in heavy liquid service; pressure relief devices in liquid service; and..., valves, connectors, and agitators in heavy liquid service; pressure relief devices in light liquid...

  16. 40 CFR 63.173 - Standards: Agitators in gas/vapor service and in light liquid service.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 10 2014-07-01 2014-07-01 false Standards: Agitators in gas/vapor... Equipment Leaks § 63.173 Standards: Agitators in gas/vapor service and in light liquid service. (a)(1) Each agitator shall be monitored monthly to detect leaks by the methods specified in § 63.180(b) of this...

  17. 40 CFR 65.109 - Standards: Agitators in gas/vapor service and in light liquid service.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 15 2010-07-01 2010-07-01 false Standards: Agitators in gas/vapor... Standards: Agitators in gas/vapor service and in light liquid service. (a) Compliance schedule. The owner or...) Leak detection—(1) Monitoring method. Each agitator seal shall be monitored monthly to detect leaks...

  18. 40 CFR 65.109 - Standards: Agitators in gas/vapor service and in light liquid service.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 16 2012-07-01 2012-07-01 false Standards: Agitators in gas/vapor... Standards: Agitators in gas/vapor service and in light liquid service. (a) Compliance schedule. The owner or...) Leak detection—(1) Monitoring method. Each agitator seal shall be monitored monthly to detect leaks...

  19. 40 CFR 63.1028 - Agitators in gas and vapor service and in light liquid service standards.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 10 2010-07-01 2010-07-01 false Agitators in gas and vapor service and... Standards § 63.1028 Agitators in gas and vapor service and in light liquid service standards. (a) Compliance... in the referencing subpart. (b) (c) Leak detection—(1) Monitoring method. Each agitator seal shall...

  20. 40 CFR 63.1010 - Pumps, valves, connectors, and agitators in heavy liquid service; pressure relief devices in...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... agitators in heavy liquid service; pressure relief devices in liquid service; and instrumentation systems..., connectors, and agitators in heavy liquid service; pressure relief devices in liquid service; and... comply with paragraphs (b)(1) and (b)(2) of this section. Pumps, valves, connectors, and agitators...

  1. 40 CFR 63.1010 - Pumps, valves, connectors, and agitators in heavy liquid service; pressure relief devices in...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... agitators in heavy liquid service; pressure relief devices in liquid service; and instrumentation systems..., connectors, and agitators in heavy liquid service; pressure relief devices in liquid service; and... comply with paragraphs (b)(1) and (b)(2) of this section. Pumps, valves, connectors, and agitators...

  2. 40 CFR 63.173 - Standards: Agitators in gas/vapor service and in light liquid service.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 10 2012-07-01 2012-07-01 false Standards: Agitators in gas/vapor... Equipment Leaks § 63.173 Standards: Agitators in gas/vapor service and in light liquid service. (a)(1) Each agitator shall be monitored monthly to detect leaks by the methods specified in § 63.180(b) of this...

  3. 40 CFR 63.173 - Standards: Agitators in gas/vapor service and in light liquid service.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 9 2011-07-01 2011-07-01 false Standards: Agitators in gas/vapor... Equipment Leaks § 63.173 Standards: Agitators in gas/vapor service and in light liquid service. (a)(1) Each agitator shall be monitored monthly to detect leaks by the methods specified in § 63.180(b) of this...

  4. Effect of individualized music on agitation in individuals with dementia who live at home.

    PubMed

    Park, Heeok; Pringle Specht, Janet K

    2009-08-01

    This pilot study investigated the effect of individualized music on agitation in individuals with dementia who live at home. Fifteen individuals listened to their preferred music for 30 minutes prior to peak agitation time, two times per week for 2 weeks, followed by no music intervention for 2 weeks. The process was repeated once. The findings showed that mean agitation levels were significantly lower while listening to music than before listening to the music. The findings of this pilot study suggest the importance of music intervention for individuals with dementia who live at home.

  5. NARSTO EMISSION INVENTORY ASSESSMENT

    EPA Science Inventory

    The NARSTO Ozone and Particulate Matter Assessments emphasized that emission inventories are critical to the success of air quality management programs and that emissions inventories in Canada, Mexico, and the United States need improvement to meet expectations for quality, timel...

  6. Science Inventory | US EPA

    EPA Pesticide Factsheets

    The Science Inventory is a searchable database of research products primarily from EPA's Office of Research and Development. Science Inventory records provide descriptions of the product, contact information, and links to available printed material or websites.

  7. Hydraulic characteristics simulation of an innovative self-agitation anaerobic baffled reactor (SA-ABR).

    PubMed

    Qi, Wei-Kang; Hojo, Toshimasa; Li, Yu-You

    2013-05-01

    An investigation was conducted on a self-agitation anaerobic baffled reactor (SA-ABR) with agitation caused solely by the release of stored gas. The compound in the reactor is mixed without the use of any mechanical equipment and electricity. The computational fluid dynamics (CFD) simulation used to provide details of the flow pattern and information about the agitation process and a solid basis for design and optimization purposes. Every self-agitation cycle could be separated into the pressure energy storage process, the exergonic process and the buffer stage. The reactor is regarded as the combination of continuous stirred tank reactor and a small plug flow reactor. The liquid level and diffusion varies widely depending on the length of the U-tube. The compound transition phenomenon in the 1st chamber mainly occurs during the energy exergonic process and buffer stage. The fluid-diffusion in the 3rd and 4th chambers mainly happens after the buffer period.

  8. A meta-analytic review of the association between agitation and suicide attempts.

    PubMed

    Rogers, Megan L; Ringer, Fallon B; Joiner, Thomas E

    2016-08-01

    Agitation has been implicated as an acute risk factor for suicidal behavior, yet the literature to date has not been consolidated to better understand this relationship. We conducted a meta-analysis of the association between agitation and suicidal behavior to synthesize the existing literature (k=13 studies) and point out future directions for research. Results indicated that the association between agitation and suicidal behavior is moderate (Hedge's g=0.40, p=0.007, 95% CI [0.08, 0.72]). Follow-up meta-regressions revealed that age, gender, and year of publication were not significant moderators of the magnitude of this relationship. However, there was evidence of publication bias, as shown by a funnel plot and Egger's test. These findings suggest the importance of future research that examines the nature of the association between agitation and suicidal behavior longitudinally and with novel research designs, as implications for clinical practice and suicide risk assessment may be substantial.

  9. Flocculation of colloidal sols: Diffusion-controlled vs agitation-induced flocculation

    NASA Technical Reports Server (NTRS)

    1979-01-01

    A proposal for carrying out flocculation experiments in microgravity is presented. These experiments might allow a correlation between theory and experiment. First, all particles, whether single primary particles or aggregates of primary particles would not settle or cream at any agitation rate, or even in the absence of agitation. This failure to separate would keep all aggregates active, still serving as centers for diffusion-controlled flocculation. Keeping all particles suspended would allow the possibility of determining the total number of particles as a function of time from beginning to end of flocculation. Finally, the experiments would allow a definite separation diffusion-controlled and agitation-induced flocculation by studying diffusion-controlled flocculation with and without agitation.

  10. Biological activity of insulin in GMO gels and the effect of agitation.

    PubMed

    Sadhale, Y; Shah, J C

    1999-11-25

    Glyceryl monooleate (GMO)-water cubic phase gel was previously shown to protect insulin from agitation induced aggregation. However, it is not known if insulin is biologically active in the gel and what effect agitation has on insulin in the gel. Therefore, the objective was to determine the stability of insulin in cubic phase gel in terms of its biological activity in a suitable animal model such as Sprague-Dawley rats. Effect of agitation on biological activity of insulin in cubic phase GMO gel was determined by subcutaneous injections of the agitated and non-agitated gels to two groups of previously fasted rats and measuring the effect on their blood glucose levels. Two groups of rats administered with agitated insulin solution and normal saline were used as controls. The biological activity of insulin was evaluated by comparing AAC (area above the blood glucose level-time curve, in %-h), C(max) (maximum % decrease in blood glucose levels) and t(max) (time required to attain C(max), in h) values for the four groups of rats. Since cubic phase gel is highly viscous, therapeutic equivalency of insulin in the lamellar phase gel, which converts in situ into cubic phase gel, was compared to insulin solution with normal saline as the control, using AAC, C(max) and t(max) of the blood glucose profile. Insulin was biologically active in both agitated and non-agitated gels; however, upon agitation, insulin in solution totally lost its hypoglycemic activity. Agitation of insulin in the cubic phase gel was seen to have very little deleterious effect on its biological activity. Insulin in the lamellar phase gel was not only biologically active but also therapeutically equivalent to insulin solution based on AAC (327.9+/-100.8 and 431.7+/-113.3), C(max) (57. 1+/-7.0 and 70.2+/-6.5) and t(max) (2.8+/-0.7 and 4.0+/-1.7) for the lamellar phase gel and insulin solution, respectively (no significant difference, P0.05). In summary, GMO cubic phase gel protected insulin from

  11. Caring for relatives with agitation at home: a qualitative study of positive coping strategies

    PubMed Central

    Jesnick, Leah; Turner, Rebecca; Leavey, Gerard; Livingston, Gill

    2017-01-01

    Background Trials of psychological interventions for reducing agitation in people with dementia living at home have been unsuccessful. Aims To inform future interventions by identifying successful strategies of family carers with relatives with dementia and agitation living at home. Method Qualitative in-depth individual interviews were performed with 18 family carers. We used thematic analysis to identify emerging themes. Results Carers described initial surprise and then acceptance that agitation is a dementia symptom and learned to respond flexibly. Their strategies encompassed: prevention of agitation by familiar routine; reduction of agitation by addressing underlying causes and using distraction; prevention of escalation by risk enablement, not arguing; and control of their emotional responses by ensuring their relative’s safety then walking away, carving out some time for themselves and using family and services for emotional and practical help. Conclusions These strategies can be manualised and tested in future randomised controlled trials for clinical effectiveness in reducing agitation in people with dementia living at home. Declaration of interest None. Copyright and usage © The Royal College of Psychiatrists 2017. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) license. PMID:28243464

  12. Effect of ketorolac on the prevention of emergence agitation in children after sevoflurane anesthesia

    PubMed Central

    Kim, Deokkyu; Doo, A Ram; Lim, Hyungsun; Son, Ji-Seon; Lee, Jun-Rae; Han, Young-Jin

    2013-01-01

    Background The purpose of this study was to evaluate the effects of ketorolac on the incidence and severity of emergence agitation in children recovering from sevoflurane anesthesia. Methods Eighty-five children aged 3 to 7 years were randomly assigned to the control group or the ketorolac group (1 mg/kg ketorolac). The children were evaluated by the Pediatric Anesthesia Emergence Delirium Scale and a four-point agitation scale. Results The median agitation scores did not differ significantly between the two groups. The overall incidence of emergence agitation was similar in the two groups (41% in the control group vs. 32% in the ketorolac group, P = 0.526). The number of children who received rescue drugs for treatment of emergence agitation was not significantly different between the two groups. Conclusions The administration of 1 mg/kg of ketorolac is not effective in decreasing the incidence and severity of emergence agitation in children aged 3 to 7 years after sevoflurane anesthesia. PMID:23560190

  13. Effect of agitation on ligninase activity and ligninase production by Phanerochaete chrysosporium

    SciTech Connect

    Venkatadri, R.; Irvine, R.L. )

    1990-09-01

    The white rot fungus Phanerochaete chrysosporium produces extracellular ligninases as part of its idiophasic ligninolytic system. Agitation has been widely reported to suppress both ligninase production and lignin degradation. Results show that mechanical inactivation of ligninase is possibly the reason why ligninase accumulation is low or absent in agitated shake-flask cultures. Agitation seems to affect the catalytic activity of ligninase and has no apparent effect on either the rate of ligninase production or the physiology of P. chrysosporium. The detergents Tween 20, Tween 40, Tween 60, Tween 80, and 3-((3-cholamidopropyl)dimethylammonio)-1-propanesuflonate (CHAPS) are able to protect both purified ligninase and extant ligninase in culture fluids (free of biomass) against mechanical inactivation due to agitation. Addition of Tween 80 at the end of primary growth to agitated shake flasks containing either pelleted or immobilized mycelial cultures results in production and maintenance of high levels of ligninase activity over several days under conditions of high agitation. Possible mechanisms by which the detergents could protect ligninase are discussed.

  14. Computational fluid dynamics (CFD) insights into agitation stress methods in biopharmaceutical development.

    PubMed

    Bai, Ge; Bee, Jared S; Biddlecombe, James G; Chen, Quanmin; Leach, W Thomas

    2012-02-28

    Agitation of small amounts of liquid is performed routinely in biopharmaceutical process, formulation, and packaging development. Protein degradation commonly results from agitation, but the specific stress responsible or degradation mechanism is usually not well understood. Characterization of the agitation stress methods is critical to identifying protein degradation mechanisms or specific sensitivities. In this study, computational fluid dynamics (CFD) was used to model agitation of 1 mL of fluid by four types of common laboratory agitation instruments, including a rotator, orbital shaker, magnetic stirrer and vortex mixer. Fluid stresses in the bulk liquid and near interfaces were identified, quantified and compared. The vortex mixer provides the most intense stresses overall, while the stir bar system presented locally intense shear proximal to the hydrophobic stir bar surface. The rotator provides gentler fluid stresses, but the air-water interfacial area and surface stresses are relatively high given its low rotational frequency. The orbital shaker provides intermediate-level stresses but with the advantage of a large stable platform for consistent vial-to-vial homogeneity. Selection of experimental agitation methods with targeted types and intensities of stresses can facilitate better understanding of protein degradation mechanisms and predictability for "real world" applications.

  15. Delayed egg hatching of Anopheles gambiae (Diptera: Culicidae) pending water agitation.

    PubMed

    Ebrahimi, Babak; Shakibi, Sanam; Foster, Woodbridge A

    2014-05-01

    Mosquito eggs laid on water surfaces typically hatch spontaneously soon after the embryos within them become fully formed first-instar larvae. However, we have found that Anopheles gambiae Giles, an important vector of malaria in Africa, exhibits delayed hatching until the water surface is agitated, a feature overlooked in most laboratory colonies. Agitation within 24 h postoviposition, before embryonation was complete, failed to stimulate delayed postembryonic hatching of isolated eggs on the following day (day 2), when < 1% had hatched spontaneously. However, 5 min of water agitation of these dormant pharate first-instar larvae on day 2 resulted in an almost immediate hatch of 63.3 versus 0% of nonagitated controls, plus another 3.9 versus 0.3%, respectively, during the following 24 h. With daily agitation, installment hatching occurred mainly during 2-6 d postoviposition. The mean cumulative hatch after 7 d of daily agitation was 83.1 versus 1.1% of nonagitated eggs. Experiments with eggs in groups demonstrated that egg density and activity of already-hatched larvae had no stimulatory effect. Eggs stored 1-4 wk at 25.5 or at 15.5 degrees C, and then agitated daily for 6 d at 25.5 degrees C, showed a gradual decline in viability. Viability was sustained longer at the lower temperature. Implications of agitation-induced egg hatching for rainy-season and dry-season ecology of An. gambiae are discussed. Suspended hatching and cool storage already are proving convenient for efficient mass rearing and accurate modeling of weather-based population dynamics.

  16. The effects of excipients on protein aggregation during agitation: an interfacial shear rheology study.

    PubMed

    Liu, Lu; Qi, Wei; Schwartz, Daniel K; Randolph, Theodore W; Carpenter, John F

    2013-08-01

    We investigated the effects of excipients in solutions of keratinocyte growth factor 2 (KGF-2) on protein aggregation during agitation as well as on interfacial shear rheology at the air-water interface. Samples were incubated with or without agitation, and in the presence or absence of the excipients heparin, sucrose, or polysorbate 80 (PS80). The effect of excipients on the extent of protein aggregation was determined by UV-visible spectroscopy and micro-flow imaging. Interfacial shear rheology was used to detect the gelation time and strength of protein gels at the air-water interface. During incubation, protein particles of size ≥1 μm and insoluble aggregates formed faster for KGF-2 solutions subjected to agitation. Addition of either heparin or sucrose promoted protein aggregation during agitation. In contrast, PS80 substantially inhibited agitation-induced KGF-2 aggregation but facilitated protein particulate formation in quiescent solutions. The combination of PS80 and heparin or sucrose completely prevented protein aggregation during both nonagitated and agitated incubations. Interfacial rheological measurements showed that KGF-2 in buffer alone formed an interfacial gel within a few minutes. In the presence of heparin, KGF-2 interfacial gels formed too quickly for gelation time to be determined. KGF-2 formed gels in about 10 min in the presence of sucrose. The presence of PS80 in the formulation inhibited gelation of KGF-2. Furthermore, the interfacial gels formed by the protein in the absence of PS80 were reversible when PS80 was added to the samples after gelation. Therefore, there is a correspondence between formulations that exhibited interfacial gelation and formulations that exhibited agitation-induced aggregation.

  17. CFD simulation of local and global mixing time in an agitated tank

    NASA Astrophysics Data System (ADS)

    Li, Liangchao; Xu, Bin

    2017-01-01

    The Issue of mixing efficiency in agitated tanks has drawn serious concern in many industrial processes. The turbulence model is very critical to predicting mixing process in agitated tanks. On the basis of computational fluid dynamics(CFD) software package Fluent 6.2, the mixing characteristics in a tank agitated by dual six-blade-Rushton-turbines(6-DT) are predicted using the detached eddy simulation(DES) method. A sliding mesh(SM) approach is adopted to solve the rotation of the impeller. The simulated flow patterns and liquid velocities in the agitated tank are verified by experimental data in the literature. The simulation results indicate that the DES method can obtain more flow details than Reynolds-averaged Navier-Stokes(RANS) model. Local and global mixing time in the agitated tank is predicted by solving a tracer concentration scalar transport equation. The simulated results show that feeding points have great influence on mixing process and mixing time. Mixing efficiency is the highest for the feeding point at location of midway of the two impellers. Two methods are used to determine global mixing time and get close result. Dimensionless global mixing time remains unchanged with increasing of impeller speed. Parallel, merging and diverging flow pattern form in the agitated tank, respectively, by changing the impeller spacing and clearance of lower impeller from the bottom of the tank. The global mixing time is the shortest for the merging flow, followed by diverging flow, and the longest for parallel flow. The research presents helpful references for design, optimization and scale-up of agitated tanks with multi-impeller.

  18. Effects of viewing a preferred nature image and hearing preferred music on engagement, agitation, and mental status in persons with dementia

    PubMed Central

    Eggert, Julia; Vincent, Ellen; Parker, Veronica; Daily, Shaundra B; Pham, Hiep; Watson, Alison Turner; Summey, Hollie; Roy, Tania

    2015-01-01

    Background: The purpose of the described exploratory study was to test proactive strategies for enhancing engagement and cognitive ability while diminishing dementia-related disordered behaviors of those diagnosed with Alzheimer’s disease and other dementias. Study participants resided in an Memory Care unit of an assisted living community. Method: The researchers measured the effects of exposure to music and nature images on engagement using the Individualized Dementia Engagement and Activities Scale tool, on cognitive ability using the Montreal Cognitive Assessment, and on agitation using the Cohen-Mansfield Agitation Inventory. Result: The within-subject study design revealed that use of both music and nature images hold promise for reducing undesirable behaviors and improving engagement of residents. Conclusion: The authors suggest caregivers for those with Alzheimer’s disease and other dementias can effectively use nature images and music to improve engagement and reduce disordered behaviors, thus potentially enhancing quality of life for the care recipient as well as the caregiver while possibly reducing the costs of medications used to control dementia-related undesirable behaviors. PMID:26770801

  19. Interactive inventory monitoring

    NASA Technical Reports Server (NTRS)

    Spremo, Stevan M. (Inventor); Udoh, Usen E. (Inventor)

    2009-01-01

    Method and system for monitoring present location and/or present status of a target inventory item, where the inventory items are located on one or more inventory shelves or other inventory receptacles that communicate with an inventory base station through use of responders such as RFIDs. A user operates a hand held interrogation and display (IAD) module that communicates with, or is part of, the base station, to provide an initial inquiry. Information on location(s) of the target inventory item is also indicated visibly and/or audibly on the receptacle(s) for the user. Status information includes an assessment of operation readiness and a time, if known, that the specified inventory item or class was last removed or examined or modified. Presentation of a user access level may be required for access to the target inventory item. Another embodiment provides inventory information for a stack as a sight-impaired or hearing-impaired person passes adjacent to that stack.

  20. Comparing landslide inventory maps

    NASA Astrophysics Data System (ADS)

    Galli, Mirco; Ardizzone, Francesca; Cardinali, Mauro; Guzzetti, Fausto; Reichenbach, Paola

    Landslide inventory maps are effective and easily understandable products for both experts, such as geomorphologists, and for non experts, including decision-makers, planners, and civil defense managers. Landslide inventories are essential to understand the evolution of landscapes, and to ascertain landslide susceptibility and hazard. Despite landslide maps being compiled every year in the word at different scales, limited efforts are made to critically compare landslide maps prepared using different techniques or by different investigators. Based on the experience gained in 20 years of landslide mapping in Italy, and on the limited literature on landslide inventory assessment, we propose a general framework for the quantitative comparison of landslide inventory maps. To test the proposed framework we exploit three inventory maps. The first map is a reconnaissance landslide inventory prepared for the Umbria region, in central Italy. The second map is a detailed geomorphological landslide map, also prepared for the Umbria region. The third map is a multi-temporal landslide inventory compiled for the Collazzone area, in central Umbria. Results of the experiment allow for establishing how well the individual inventories describe the location, type and abundance of landslides, to what extent the landslide maps can be used to determine the frequency-area statistics of the slope failures, and the significance of the inventory maps as predictors of landslide susceptibility. We further use the results obtained in the Collazzone area to estimate the quality and completeness of the two regional landslide inventory maps, and to outline general advantages and limitations of the techniques used to complete the inventories.

  1. The Effect on Apheresis Platelet Quality During Shipment with Continued Interruption of Agitation for 24 and 48 Hours

    DTIC Science & Technology

    2006-01-26

    The Effect on Apheresis Platelet Quality During Shipment With Continued Interruption of Agitation for 24 and 48 Hours R.R. Leslie-Holt and V. W...EFFECT ON APHERESIS PLATELET QUALITY DURING SHIPMENT WITH CONTINUED INTERRUPTION OF AGITATION FOR 24 AND 48 HOURS. 6. AUTHOR(S) CAPT LESLIEHOLT RONNI...maintaining an oxidative metabolism. Key Words: Agitation, apheresis , lactate, pH, platelet , quality 4 INTRODUCTION The Armed Services Blood Program

  2. The Preschool Interest Inventory.

    ERIC Educational Resources Information Center

    Rugg, Mary E.; Wood, Sue Sims

    The Preschool Interest Inventory (PSII) has been developed to meet the need for an informal measure of the interests, play behaviors, and communication skills of young children between the ages of 2 and 6 years, particularly those exhibiting delays in language development. The first step in the Inventory process is the Caregiver Interview. In the…

  3. Effect of agitation on removal of acetic acid from pretreated hydrolysate by activated carbon.

    PubMed

    Priddy, Sarah A; Hanley, Thomas R

    2003-01-01

    The effect of agitation on the adsorption of acetic acid by activated carbon was tested utilizing an external mass transfer-diffusion model. Simulated pretreated biomass was contacted with activated carbon under prescribed conditions of temperature and agitation. Adsorption isotherm studies are presented as well as batch kinetic rate studies. Use of these data enabled the determination of isotherm constants, an external mass transfer coefficient, and an effective diffusivity for each agitation rate studied. The external film coefficient results ranged from 33.62 microm/s to a complete absence of external mass transfer resistance, and the diffusivity results ranged from 0.8625 to 10.70 microm(2)/s. The optimum combination of no external film resistance, and highest diffusivity, 10.70 microm(2)/s, occurred at 250 rpm and 25 degrees C. The results of these models and the experimental parameters suggested an efficacious method and conditions for the removal of this undesirable chemical.

  4. Stabilization of tetanus toxoid formulation containing aluminium hydroxide adjuvant against agitation.

    PubMed

    Solanki, Vipul A; Jain, Nishant K; Roy, Ipsita

    2012-02-28

    The aggregation of tetanus toxoid leads to reduced bioavailability of the vaccine and failure of immunization programmes in many parts of the globe. One of the main reasons for denaturation and aggregation of tetanus toxoid formulations is agitation of the protein during transport. We have identified that agitation leads to collapse of the gel matrix of aluminium hydroxide which is used as an adjuvant in these preparations. This results in desorption of the toxoid from the matrix, which then loses its antigenicity due to agitation-induced denaturation of the protein. We show that incorporation of some compatible osmolytes like sorbitol, glucose and arginine, but not trehalose, is able to protect the adjuvant matrix from degradation, and retain the integrity of the vaccine preparation in terms of its antigenicity.

  5. The effects of researcher-composed music at mealtime on agitation in nursing home residents with dementia.

    PubMed

    Ho, Shu-Yuan; Lai, Hui-Ling; Jeng, Shaw-Yeu; Tang, Chih-Wei; Sung, Huei-Chuan; Chen, Pin-Wen

    2011-12-01

    This study examined the effects of music at mealtimes on agitation in 22 nursing home residents with dementia. We used a pretest-posttest research design. We played researcher-composed music to residents at each of two mealtimes daily over a consecutive 4-week period. We observed and recorded agitation 24 hours daily for the 4-week period and the following 2-week period. Results revealed a significant decline in mean agitation scores. A cumulative dose effect and a short-term linger effect were observed. Findings suggest that soothing music may be beneficial in managing agitation in nursing home residents with dementia.

  6. Study of dissolution hydrodynamic conditions versus drug release from hypromellose matrices: the influence of agitation sequence.

    PubMed

    Asare-Addo, Kofi; Levina, Marina; Rajabi-Siahboomi, Ali R; Nokhodchi, Ali

    2010-12-01

    In this article, the influence of agitation in descending and ascending sequences as a systematic method development process for potentially discriminating fed and fasted states and evaluation of its effects on the drug release from swelling gel-forming hydrophilic matrix tablets were investigated. Theophylline extended release (ER) matrices containing hypromellose (hydroxypropyl methylcellulose (HPMC)) were evaluated in media with a pH range of 1.2-7.5, using an automated USP type III, Bio-Dis dissolution apparatus at 5, 10, 15, 20, 25 and 30 dips per minute (dpm). Agitation had a profound effect on the drug release from the HPMC K100LV matrices. Drug release in pH 1.2 changed from about 40% at 5 dpm to about 80% at 30 dpm over a 60 min period alone. The matrices containing HPMC K4M, K15M and K100M however were not significantly affected by the agitation rate. The similarity factor f2 was calculated using drug release at 10 dpm as a reference. The ascending agitations of 5-30 dpm and the descending order of agitation 30-5 dpm were also evaluated. Anomalous transport was the only kinetic of release for the K4M, K15M and K100M tablet matrices. The lower viscous polymer of K100LV had some matrices exhibiting Fickian diffusion as its kinetics of release. The use of systematic change of agitation method may indicate potential fed and fasted effects on drug release from hydrophilic matrices.

  7. Time to response to citalopram treatment for agitation in Alzheimer's disease

    PubMed Central

    Weintraub, Daniel; Drye, Lea T.; Porsteinsson, Anton P.; Rosenberg, Paul B.; Pollock, Bruce G.; Devanand, D.P.; Frangakis, Constantine; Ismail, Zahinoor; Marano, Christopher; Meinert, Curtis L.; Mintzer, Jacobo E.; Munro, Cynthia A.; Pelton, Gregory; Rabins, Peter V.; Schneider, Lon S.; Shade, David M.; Yesavage, Jerome; Lyketsos, Constantine G.

    2015-01-01

    Background Agitation is a common and significant problem in Alzheimer’s disease (AD). In the recent Citalopram for Agitation in Alzheimer’s Disease (CitAD) study, citalopram was efficacious for the treatment of AD agitation. Here we examined the time course and predictors of response to treatment. Methods Response in CitAD was defined as a modified Alzheimer Disease Cooperative Study-Clinical Global Impression of Change (mADCS-CGIC) score of 1 or 2, or a Neurobehavioral Rating Scale agitation subscale (NBRS-A) score reduction ≥50% from baseline. “Stable early response” was defined as meeting the aforementioned criteria at both weeks 3 and 9, “late response” was response at week 9 but not at week 3, and “unstable response” was response at week 3 but not at week 9. Results In the primary analyses, citalopram was superior to placebo on both the CGIC and the NBRS-A response measures. There were little between-group differences in response rates in the first three weeks of the study (21% vs 19% on the CGIC). Citalopram patients were more likely than placebo patients to be a late responder (18% vs. 8% on CGIC, Fisher’s exact p=0.09; 31% vs. 15% on NBRS-A, Fisher’s exact p=0.02). Approximately half (45–56%) of citalopram responders at end-of-study achieved response later in the study, compared with 30–44% of placebo responders. Discussion Treatment with citalopram for agitation in AD needs to be at least nine weeks in duration to allow sufficient time for full response, and study duration is an important factor to consider in the design of clinical trials for agitation in Alzheimer’s disease. PMID:26238225

  8. The influence of turbulence on aggregation of small particles in agitated vessels

    NASA Astrophysics Data System (ADS)

    Kusters, Karel Antonius

    The influence of the hydrodynamics in baffled turbine agitated vessels on the turbulent coagulation of small solid particles is studied, with focus on the dependence of the aggregate size on stirrer speed, concentration of solids, destabilizer concentration, and vessel size. The following studies are presented: aggregation theory; hydrodynamics in stirred tanks; numerical particle tracking in a turbine agitated vessel; aggregation kinetics in stirred tanks; and maximum aggregate size in stirred tanks. The application of the model to describe the aggregation process in strirred tanks to experimental conditions other than those tested and to particulate systems with different physical properties is discussed.

  9. Interactive Inventory Monitoring

    NASA Technical Reports Server (NTRS)

    Garud, Sumedha

    2013-01-01

    Method and system for monitoring present location and/or present status of a target inventory item, where the inventory items are located on one or more inventory shelves or other inventory receptacles that communicate with an inventory base station through use of responders such as RFIDs. A user operates a hand held interrogation and display (lAD) module that communicates with, or is part of the base station to provide an initial inquiry. lnformation on location(s) of the larget invenlory item is also indicated visibly and/or audibly on the receptacle(s) for the user. Status information includes an assessment of operation readiness and a time, if known, that the specified inventory item or class was last removed or examined or modified. Presentation of a user access level may be required for access to the target inventgory item. Another embodiment provides inventory informatin for a stack as a sight-impaired or hearing-impaired person adjacent to that stack.

  10. Women, Scientists, Agitators: Magazine Portrayal of Rachel Carson and Theo Colborn.

    ERIC Educational Resources Information Center

    Corbett, Julia B.

    2001-01-01

    Utilizes a theoretical framework of the media's role in reporting conflict and uncertain science, and feminism and science in a thematic analysis of magazine coverage given Rachel Carson and "the Rachel Carson of '90s," Theo Colborn. Notes that Carson and Colborn's identities as women, scientists, and agitators led critics to charge that…

  11. The effect of agitation state on polyol synthesis of silver nanowire

    NASA Astrophysics Data System (ADS)

    Amirjani, Amirmostafa; Marashi, Pirooz; Fatmehsari, Davoud Haghshenas

    2016-11-01

    In the present work, the effect of agitation rate on the growth mechanism of silver nanowires is evaluated during polyol process. It was found that increasing the agitation rate leads to the increase in the oxygen transfer rate which in turn enhances the oxidative etching conditions leading to the formation of a variety of nanostructures (nanoparticles, nanorods and nanowires). In light of the obtained experimental results, it can be stated that agitation is not essential for synthesizing silver nanowires by polyol method and it is possible to obtain uniform nanowires with ~200 nm diameters in the length of 20-30 microns several microns length in the stagnant condition. By setting the stirring rate at 200 rpm, it is possible to reduce the nanowires diameters to ~130 nm and the obtained nanostructures are still mono-dispersed. This paper provides complete information about the effect of agitation state on the polyol synthesis of silver nanowires which is truly useful for further studies in this case.

  12. Boiling heat transfer enhancement of nanofluids on a smooth surface with agitation

    NASA Astrophysics Data System (ADS)

    Kong, Xin; Qi, Baojin; Wei, Jinjia; Li, Wei; Ding, Jie; Zhang, Yonghai

    2016-12-01

    The pool boiling heat transfer performance on a smooth silicon chip surface with agitation was experimentally investigated in this study. The nanofluids (Ag/alcohol) of 0.02 % volume concentration and ethyl alcohol with purification over 99.9 % were the two contrast working fluids. For each group, subcoolings of 40, 50 and 60 K were conducted under atmospheric pressure. To enhance the heat transfer performance, an agitating device was fixed above the top of the chip. The experimental results indicated that nanofluids could enhance the heat transfer performance especially in the nucleate boiling region. The heat transfer coefficient was significantly increased with nanofluids, while the critical heat flux (CHF) was nearly not changed. In the agitation Reynolds number of 20,300, the heat transfer performance of nanofluids was significantly enhanced in the convection region, and the CHF was increased by more than 25 % for all groups. This boiling phenomenon was observed for both nanofluids and alcohol groups. Meanwhile, the boiling curves of different liquid subcoolings in the nucleate region were quite similar to each other under agitation.

  13. 5-day storage of platelet concentrates in CLX containers: effect of type of agitation.

    PubMed

    Snyder, E L; Bookbinder, M; Kakaiya, R; Ferri, P; Kiraly, T

    1983-01-01

    To determine the degree of platelet damage produced by different modes of agitation during storage of concentrates for 5 days in CLX blood bags, we studied pH, platelet counts, release of LDH and beta thromboglobulin, morphology and osmotic recovery. Platelets were maintained at 20-24 degrees C on elliptical, 6-rpm circular, 2-rpm circular and flat bed agitators. At 72-120 h platelet concentrates stored on the flat bed shaker had significantly lower pH values than units stored on the elliptical or on either of the circular rotators (p less than 0.05). The percent LDH discharged was highest for the units stored on the elliptical rotator (p less than 0.05). Remaining tests of platelet function were not significantly different for concentrates stored on any of the four agitators. Flat bed shakers were unable to resuspend the platelet 'button' which formed after the final preparative centrifugation. Based on our in vitro studies, we conclude that due to problems with low pH values, flat bed shakers may not be optimal for storing platelet concentrates in CLX blood bags and that some other form of agitation should be used.

  14. Pharmacological Management of Agitation and Aggression in an Adolescent with Autism

    ERIC Educational Resources Information Center

    Kratochvil, Christopher J.; Findling, Robert L.; McDougle, Christopher J.; Scahill, Lawrence; Hamarman, Stephanie

    2005-01-01

    This article provides an "autism vignette" and then poses an evaluative question to several autism specialists, documenting their varied responses to the scenario and question posed. A 13-year-old boy with autism and severe mental retardation presented to the inpatient psychiatric unit due to a recent increase in agitation and physical aggression.…

  15. Using Simulation to Train Junior Psychiatry Residents to Work with Agitated Patients: A Pilot Study

    ERIC Educational Resources Information Center

    Zigman, Daniel; Young, Meredith; Chalk, Colin

    2013-01-01

    Objective: This article examines the benefit and feasibility of introducing a new, simulation-based learning intervention for junior psychiatry residents. Method: Junior psychiatry residents were invited to participate in a new simulation-based learning intervention focusing on agitated patients. Questionnaires were used to explore the success of…

  16. Escalation of Agitative Rhetoric: A Case Study of Mattachine Midwest, 1967-1970.

    ERIC Educational Resources Information Center

    Darsey, James

    This paper examines the adequacy of Bowers and Ochs' theory of social movements as applied to the escalating agitative strategies of a dissident group, the homosexual-rights organization Mattachine Midwest. The group's activities are described chronologically, in terms of the strategies employed: petition, promulgation, polarization,…

  17. Brief Report: Retrospective Case Series of Oxcarbazepine for Irritability/Agitation Symptoms in Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Douglas, Jessica F.; Sanders, Kevin B.; Benneyworth, M. Hannah; Smith, Jessica L.; DeJean, Virginia M.; McGrew, Susan G.; Veenstra-VanderWeele, Jeremy

    2013-01-01

    We examined response to oxcarbazepine prescribed for irritability/agitation symptoms in a retrospective case series of 30 patients with Autism Spectrum Disorder (ASD). The average patient was 12.0 years old (range 5-21) and taking two other psychotropic medications (range 0-4). Fourteen patients (47 %) had a clinical global impression of…

  18. Effect of agitation and storage temperature on water sorption and solubility of adhesive systems.

    PubMed

    Argolo, Saryta; Mathias, Paula; Aguiar, Thaiane; Lima, Adriano; Santos, Sara; Foxton, Richard; Cavalcanti, Andrea

    2015-01-01

    The purpose of this study was to evaluate the influence of storage temperature and flask agitation on the water sorption (WS) and solubility (SL) of simplified adhesive systems. Seventy-two disc-shaped specimens were prepared according to the adhesive system (water/ethanol-based: Adper Single Bond 2; and water-based: One Coat Bond SL) and experimental conditions tested (mechanical agitation and storage temperature). Statistical analysis (3-way ANOVA, alpha=5%) found significantly greater WS and SL means for the water/ethanol-based system when compared to the water-based. Irrespective of factors studied, significant differences in WS and SL were noted between cold and room temperatures, with greater values been obtained at 1°C, and lower ones at 20°C. Agitation provided increased WS for both materials at all temperatures, but did not affect their SL. The mechanical agitation of the flask may negatively affect the dynamics of diffusion of simplified adhesive systems, even at extremely cold or warm temperatures.

  19. Effects of hydrostatic pressure, agitation and CO2 stress on Phytophthora nicotianae zoospore survival

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Phytophthora nicotianae Breda de Haan was used as a model pathogen to investigate the effects of hydrostatic pressure, agitation, and aeration with CO2 or breathable air on the survival of Phytophthora zoospores in water. Injecting CO2 into 2 liters of zoospore-infested water for 5 min at 110.4 ml ...

  20. Health protection well inventory

    SciTech Connect

    Janssen, J.

    1989-03-01

    This report is an inventory of the wells contained in Health Protection (HP) documents since the startup of the Savannah River Plan (SRP) and includes wells monitored by special request and SRL research wells.

  1. Shuttle Inventory Management

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Inventory Management System (SIMS) consists of series of integrated support programs providing supply support for both Shuttle program and Kennedy Space Center base opeations SIMS controls all supply activities and requirements from single point. Programs written in COBOL.

  2. Inventory count strategies.

    PubMed

    Springer, W H

    1996-02-01

    An important principle of accounting is that asset inventory needs to be correctly valued to ensure that the financial statements of the institution are accurate. Errors is recording the value of ending inventory in one fiscal year result in errors to published financial statements for that year as well as the subsequent fiscal year. Therefore, it is important that accurate physical counts be periodically taken. It is equally important that any system being used to generate inventory valuation, reordering or management reports be based on consistently accurate on-hand balances. At the foundation of conducting an accurate physical count of an inventory is a comprehensive understanding of the process coupled with a written plan. This article presents a guideline of the physical count processes involved in a traditional double-count approach.

  3. 40 CFR 63.1029 - Pumps, valves, connectors, and agitators in heavy liquid service; pressure relief devices in...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... agitators in heavy liquid service; pressure relief devices in liquid service; and instrumentation systems..., connectors, and agitators in heavy liquid service; pressure relief devices in liquid service; and... shall comply with paragraphs (b)(1) and (b)(2) of this section. Pumps, valves, connectors, and...

  4. 40 CFR 63.1029 - Pumps, valves, connectors, and agitators in heavy liquid service; pressure relief devices in...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... agitators in heavy liquid service; pressure relief devices in liquid service; and instrumentation systems..., connectors, and agitators in heavy liquid service; pressure relief devices in liquid service; and... shall comply with paragraphs (b)(1) and (b)(2) of this section. Pumps, valves, connectors, and...

  5. 40 CFR 63.1029 - Pumps, valves, connectors, and agitators in heavy liquid service; pressure relief devices in...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... agitators in heavy liquid service; pressure relief devices in liquid service; and instrumentation systems..., connectors, and agitators in heavy liquid service; pressure relief devices in liquid service; and... shall comply with paragraphs (b)(1) and (b)(2) of this section. Pumps, valves, connectors, and...

  6. 40 CFR 63.1029 - Pumps, valves, connectors, and agitators in heavy liquid service; pressure relief devices in...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... agitators in heavy liquid service; pressure relief devices in liquid service; and instrumentation systems..., connectors, and agitators in heavy liquid service; pressure relief devices in liquid service; and... shall comply with paragraphs (b)(1) and (b)(2) of this section. Pumps, valves, connectors, and...

  7. 40 CFR 63.1029 - Pumps, valves, connectors, and agitators in heavy liquid service; pressure relief devices in...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... agitators in heavy liquid service; pressure relief devices in liquid service; and instrumentation systems..., connectors, and agitators in heavy liquid service; pressure relief devices in liquid service; and... shall comply with paragraphs (b)(1) and (b)(2) of this section. Pumps, valves, connectors, and...

  8. Non-biodegradable landfill leachate treatment by combined process of agitation, coagulation, SBR and filtration

    SciTech Connect

    Abood, Alkhafaji R.; Bao, Jianguo; Du, Jiangkun; Zheng, Dan; Luo, Ye

    2014-02-15

    Highlights: • A novel method of stripping (agitation) was investigated for NH{sub 3}-N removal. • PFS coagulation followed agitation process enhanced the leachate biodegradation. • Nitrification–denitrification achieved by changing operation process in SBR treatment. • A dual filter of carbon-sand is suitable as a polishing treatment of leachate. • Combined treatment success for the complete treatment of non-biodegradable leachate. - Abstract: This study describes the complete treatment of non-biodegradable landfill leachate by combined treatment processes. The processes consist of agitation as a novel stripping method used to overcome the ammonia toxicity regarding aerobic microorganisms. The NH{sub 3}-N removal ratio was 93.9% obtained at pH 11.5 and a gradient velocity (G) 150 s{sup −1} within a five-hour agitation time. By poly ferric sulphate (PFS) coagulation followed the agitation process; chemical oxygen demand (COD) and biological oxygen demand (BOD{sub 5}) were removed at 70.6% and 49.4%, respectively at an optimum dose of 1200 mg L{sup −1} at pH 5.0. The biodegradable ratio BOD{sub 5}/COD was improved from 0.18 to 0.31 during pretreatment step by agitation and PFS coagulation. Thereafter, the effluent was diluted with sewage at a different ratio before it was subjected to sequencing batch reactor (SBR) treatment. Up to 93.3% BOD{sub 5}, 95.5% COD and 98.1% NH{sub 3}-N removal were achieved by SBR operated under anoxic–aerobic–anoxic conditions. The filtration process was carried out using sand and carbon as a dual filter media as polishing process. The final effluent concentration of COD, BOD{sub 5}, suspended solid (SS), NH{sub 3}-N and total organic carbon (TOC) were 72.4 mg L{sup −1}, 22.8 mg L{sup −1}, 24.2 mg L{sup −1}, 18.4 mg L{sup −1} and 50.8 mg L{sup −1} respectively, which met the discharge standard. The results indicated that a combined process of agitation-coagulation-SBR and filtration effectively eliminated

  9. Enhancing the adhesion strength of micro electroforming layer by ultrasonic agitation method and the application.

    PubMed

    Zhao, Zhong; Du, Liqun; Tao, Yousheng; Li, Qingfeng; Luo, Lei

    2016-11-01

    Micro electroforming is widely used for fabricating micro metal devices in Micro Electro Mechanism System (MEMS). However, there is the problem of poor adhesion strength between micro electroforming layer and substrate. This dramatically influences the dimensional accuracy of the device. To solve this problem, ultrasonic agitation method is applied during the micro electroforming process. To explore the effect of the ultrasonic agitation on the adhesion strength, micro electroforming experiments were carried out under different ultrasonic power (0W, 100W, 150W, 200W, 250W) and different ultrasonic frequencies (0kHz, 40kHz, 80kHz, 120kHz, 200kHz). The effects of the ultrasonic power and the ultrasonic frequency on the micro electroforming process were investigated by polarization method and alternating current (a.c.) impedance method. The adhesion strength between the electroforming layer and the substrate was measured by scratch test. The compressive stress of the electroforming layer was measured by X-ray Diffraction (XRD) method. The crystallite size of the electroforming layer was measured by Transmission Electron Microscopy (TEM) method. The internal contact surface area of the electroforming layer was measured by cyclic voltammetry (CV) method. The experimental results indicate that the ultrasonic agitation can decrease the polarization overpotential and increase the charge transfer process. Generally, the internal contact surface area is increased and the compressive stress is reduced. And then the adhesion strength is enhanced. Due to the different depolarization effects of the ultrasonic power and the ultrasonic frequency, the effects on strengthening the adhesion strength are different. When the ultrasonic agitation is 200W and 40kHz, the effect on strengthening the adhesion strength is the best. In order to prove the effect which the ultrasonic agitation can improve the adhesion strength of the micro devices, micro pillar arrays were fabricated under

  10. Non-biodegradable landfill leachate treatment by combined process of agitation, coagulation, SBR and filtration.

    PubMed

    Abood, Alkhafaji R; Bao, Jianguo; Du, Jiangkun; Zheng, Dan; Luo, Ye

    2014-02-01

    This study describes the complete treatment of non-biodegradable landfill leachate by combined treatment processes. The processes consist of agitation as a novel stripping method used to overcome the ammonia toxicity regarding aerobic microorganisms. The NH3-N removal ratio was 93.9% obtained at pH 11.5 and a gradient velocity (G) 150 s(-1) within a five-hour agitation time. By poly ferric sulphate (PFS) coagulation followed the agitation process; chemical oxygen demand (COD) and biological oxygen demand (BOD5) were removed at 70.6% and 49.4%, respectively at an optimum dose of 1200 mg L(-1) at pH 5.0. The biodegradable ratio BOD5/COD was improved from 0.18 to 0.31 during pretreatment step by agitation and PFS coagulation. Thereafter, the effluent was diluted with sewage at a different ratio before it was subjected to sequencing batch reactor (SBR) treatment. Up to 93.3% BOD5, 95.5% COD and 98.1% NH3-N removal were achieved by SBR operated under anoxic-aerobic-anoxic conditions. The filtration process was carried out using sand and carbon as a dual filter media as polishing process. The final effluent concentration of COD, BOD5, suspended solid (SS), NH3-N and total organic carbon (TOC) were 72.4 mg L(-1), 22.8 mg L(-1), 24.2 mg L(-1), 18.4 mg L(-1) and 50.8 mg L(-1) respectively, which met the discharge standard. The results indicated that a combined process of agitation-coagulation-SBR and filtration effectively eliminated pollutant loading from landfill leachate.

  11. Swelling and erosion properties of hydroxypropylmethylcellulose (Hypromellose) matrices--influence of agitation rate and dissolution medium composition.

    PubMed

    Kavanagh, Nicole; Corrigan, Owen I

    2004-07-26

    The effect of dissolution medium variables, such as medium composition, ionic strength and agitation rate, on the swelling and erosion of Hypromellose (hydroxypropylmethylcellulose, HPMC) matrices of different molecular weights was examined. Swelling and erosion of HPMC polymers was determined by measuring the wet and subsequent dry weights of matrices. It was possible to describe the rate of dissolution medium uptake in terms of a square root relationship and the erosion of the polymer in terms of the cube root law. The extent of swelling increased with increasing molecular weight, and decreased with increasing agitation rate. The erosion rate was seen to increase with decrease in polymer molecular weight, with a decrease in ionic strength and with increasing agitation rate. The sensitivity of polymer erosion to the degree of agitation may influence the ability of these polymers to give reproducible, agitation-independent release, compared to more rigid non-eroding matrix materials, in the complex hydrodynamic environment of the gastrointestinal tract.

  12. Initial Radionuclide Inventories

    SciTech Connect

    H. Miller

    2004-09-19

    The purpose of this analysis is to provide an initial radionuclide inventory (in grams per waste package) and associated uncertainty distributions for use in the Total System Performance Assessment for the License Application (TSPA-LA) in support of the license application for the repository at Yucca Mountain, Nevada. This document is intended for use in postclosure analysis only. Bounding waste stream information and data were collected that capture probable limits. For commercially generated waste, this analysis considers alternative waste stream projections to bound the characteristics of wastes likely to be encountered using arrival scenarios that potentially impact the commercial spent nuclear fuel (CSNF) waste stream. For TSPA-LA, this radionuclide inventory analysis considers U.S. Department of Energy (DOE) high-level radioactive waste (DHLW) glass and two types of spent nuclear fuel (SNF): CSNF and DOE-owned (DSNF). These wastes are placed in two groups of waste packages: the CSNF waste package and the codisposal waste package (CDSP), which are designated to contain DHLW glass and DSNF, or DHLW glass only. The radionuclide inventory for naval SNF is provided separately in the classified ''Naval Nuclear Propulsion Program Technical Support Document'' for the License Application. As noted previously, the radionuclide inventory data presented here is intended only for TSPA-LA postclosure calculations. It is not applicable to preclosure safety calculations. Safe storage, transportation, and ultimate disposal of these wastes require safety analyses to support the design and licensing of repository equipment and facilities. These analyses will require radionuclide inventories to represent the radioactive source term that must be accommodated during handling, storage and disposition of these wastes. This analysis uses the best available information to identify the radionuclide inventory that is expected at the last year of last emplacement, currently identified as

  13. Measurement of agitation and aggression in adult and aged neuropsychiatric patients: review of definitions and frequently used measurement scales.

    PubMed

    Volicer, Ladislav; Citrome, Leslie; Volavka, Jan

    2017-02-09

    Agitation and aggression in adult psychiatric patients with psychoses and in persons with dementia increase the burden of disease and frequently cause hospitalization. The implementation of currently available management strategies and the development of new ones is hindered by inconsistent terminology that confuses agitation with aggression. This confusion is maintained by many rating scales that fail to distinguish between these two syndromes. We review the frequently used rating scales with a particular focus on their ability to separate agitation from aggression. Agitation and aggression are two different syndromes. For example, reactive aggression is often precipitated by rejection of care and may not be associated with agitation per se. We propose, in treatment studies of behavioral symptoms of dementia and challenging behaviors in psychoses, that outcomes should be evaluated separately for agitation and aggression. This is important for investigation of drug effectiveness since the medication may be effective against one syndrome but not the other. Separate assessments of agitation and aggression should be a general principle of trial design with particular salience for registration studies of medications proposed for approval by the U.S. Food and Drug Administration and other regulatory bodies.

  14. Prosthetic inventory management.

    PubMed

    Brinkman, P; Seipel, C; Juers, A

    2001-01-01

    An improved approach to inventory management in the Operating Theatre has been initiated at Princess Alexandra Hospital. A Clinical Resource Co-ordinator (CRC) position was created to provide access to expertise in purchasing and materials management at the clinical level. A review of existing inventory management practices conducted by the CRC revealed reporting inadequacies, lack of product specialisation and inadequate control over pricing, stock levels and product usage. Through liaison with key stakeholders, a competitive tendering process was introduced which resulted in a standing offer arrangement being installed for three specialty orthopaedic areas. Outcomes of this arrangement are discussed. The importance of raising the area of prosthetic inventory management for debate in the Australian literature is also highlighted.

  15. Process agitator operating problems and equipment failures, F-Canyon Reprocessing Facility

    SciTech Connect

    Durant, W.S.; Starks, J.B.; Low, J.M.; Galloway, W.D.

    1988-09-01

    The Savannah River Laboratory (SRL) maintains a compilation of operating problems and equipment failures that have occurred in the fuel reprocessing areas of the Savannah River Plant (SRP). At present, the data bank contains more than 200,000 entries ranging from minor equipment malfunctions to incidents with the potential for injury or contamination of personnel, or for economic loss. The data bank has been used extensively for a wide variety of purposes, such as failure analyses, trend analyses, and preparation of safety analyses. Typical of the data are problems associated with the F-Canyon process agitators. This report contains a compilation of the agitator operating problems and equipment failures primarily as an aid to organizations with related equipment. Publication of these data was prompted by a number of requests for this information by other Department of Energy (DOE) sites. 4 figs., 4 tabs.

  16. Highly sensitive detection and stochastic analysis of magnetization agitation induced in a single layered magnetic wire

    NASA Astrophysics Data System (ADS)

    Yamaguchi, Akinobu; Motoi, Keiichi; Miyajima, Hideki

    2016-03-01

    This study shows that broadband magnetic noise in a ferromagnetic wire can be detected over a wide frequency range between 500 MHz and 8 GHz using a lock-in detection technique. The magnetic noise spectrum from a 20 nm-thick single-layered Fe19Ni81 wire biased with a dc current is measured as functions of an external field and dc current. This noise is caused by thermal agitation in magnetization due to ambient temperature and Joule heating. The noise behaviors are well reproduced by a stochastic model. Thus, this paper presents a stochastic analysis of magnetic noise behaviors induced by thermal agitation using a highly sensitive technique for detecting the magnetic noise in a single layered ferromagnetic wire.

  17. Dispersal of Aspergillus fumigatus from Sewage Sludge Compost Piles Subjected to Mechanical Agitation in Open Air

    PubMed Central

    Millner, Patricia D.; Bassett, David A.; Marsh, Paul B.

    1980-01-01

    Aerosolization of the thermophilous fungal opportunist Aspergillus fumigatus from mechanically agitated compost piles was examined at a pilot-scale sewage sludge composting facility and two other selected test sites. Aerosols of A. fumigatus downwind from stationary compost piles were insignificant in comparison with those downwind from agitated piles. These aerosols were generated by a front-end loader moving and dropping compost. Aerial concentrations of the fungus at distances downwind from the point of emission were used to determine an emission rate for A. fumigatus associated with the moving operations. The maximum emission rate, 4.6 × 106A. fumigatus particles per s, was used to calculate predicted concentrations in an unobstructed plume with restrictive, neutral, and dispersive atmospheric mixing conditions up to 1 km downwind from the emission source. PMID:16345563

  18. Effects of Tween 20 and Tween 80 on the stability of Albutropin during agitation.

    PubMed

    Chou, Danny K; Krishnamurthy, Rajesh; Randolph, Theodore W; Carpenter, John F; Manning, Mark Cornell

    2005-06-01

    The objectives of this work were to determine the effects of nonionic surfactants (Tween 20 and Tween 80) on agitation-induced aggregation of the recombinant fusion protein, Albutropintrade mark (human growth hormone genetically fused to human albumin), and to characterize the binding interactions between the surfactants and the protein. Knowing the binding stoichiometry would allow a rational choice of surfactant concentration to protect the protein from surface-induced aggregation. Fluorescence spectroscopy and isothermal titration calorimetry (ITC) were employed to study Albutropin surfactant binding. Albutropin was agitated at 25 +/- 2 degrees C to induce aggregation, and samples were taken during a 96-h incubation. Size-exclusion chromatography (SEC-HPLC) (HPLC, high-performance liquid chromatography) was used to detect and quantify the extent of protein aggregation. The effect of surfactants on the protein's free energy of unfolding was determined using guanidine HCl as a denaturant. Tween 20 and Tween 80 had saturable binding to Albutropin with a molar binding stoichiometry of 10:1 and 9:1 (surfactant:protein), respectively. Binding of the surfactants to Albutropin increased the free energy of unfolding by over 1 and 0.6 kcal/mol, respectively. In protein samples that were agitated in the absence of surfactant, soluble aggregates were detected within 24 h, and there was almost complete loss of monomer to soluble aggregates by the end of the 96-h experiment. At the molar binding stoichiometry, Tween 20 and Tween 80 prevented the formation of soluble aggregates, even though the concentrations of surfactants were well below their critical micelle concentrations (CMC). Tween 20 and Tween 80 protected Albutropin against agitation-induced aggregation, even at concentrations below the CMC. Equilibrium unfolding data indicate that Tween confer protection by increasing the free energy of unfolding of Albutropin.

  19. Agitation and delirium at the end of life: "We couldn't manage him".

    PubMed

    Breitbart, William; Alici, Yesne

    2008-12-24

    Delirium is the most common neuropsychiatric complication experienced by patients with advanced illness, occurring in up to 85% of patients in the last weeks of life. Using the case of Mr L, a 59-year-old man with metastatic lung cancer who developed an agitated delirium in the last week of life, we review the evaluation and management of delirium near the end of life. Although some studies have identified agitation as a central feature of delirium in 13% to 46% of patients, other studies have found up to 80% of patients near the end of life develop a hypoactive, nonagitated delirium. Both the agitated (hyperactive) and nonagitated (hypoactive) forms of delirium are harbingers of impending death and are associated with increased morbidity in patients who are terminally ill, causing distress for patients, family members, and staff. Delirium is a sign of significant physiological disturbance, usually involving multiple causes, including infection, organ failure, and medication adverse effects. Often these causes of delirium are not reversible in the dying patient, and this influences the outcomes of its management. Delirium can also significantly interfere with the recognition and control of other physical and psychological symptoms, such as pain. Unfortunately, delirium is often misdiagnosed or unrecognized and thus inappropriately treated or untreated in terminally ill patients. To manage delirium in terminally ill patients, clinicians must be able to diagnose it accurately, undertake appropriate assessment of underlying causes, and understand the benefits and risks of the available pharmacological and nonpharmacological interventions.

  20. Pumping Characteristics of a Helical Screw Agitator with a Draught Tube

    NASA Astrophysics Data System (ADS)

    Hwang, Jung-Hoon; Kim, Youn-Jea

    In the use of helical type agitator, the mixing process is usually restricted to the laminar flow regime. Common examples of laminar mixing are found where the fluid has a very high viscosity, i.e., pseudoplastic fluids. It can be indicated that a helical type agitator is sufficiently suited to the creeping flow mixing. The pumping characteristic of a Helical Screw Agitator with a draught tube (HSA) is required to evaluate its capacity for the optimal configuration of the mixing chamber. It could be executed by changing some parameters such as the number of helix, the angular velocity and the rotating direction and so on. In this study, the numerical simulation was carried out with the Eulerian multiphase mixture model and the moving mesh approximation. Some of the optimum design parameters have been developed with the aid of numerical data from the Computational Fluid Dynamics (CFD) analysis. Using the commercial code, Fluent, the pumping characteristics in the HSA are investigated from the rheological properties, and the results are graphically depicted.

  1. Helically agitated mixing in dry dilute acid pretreatment enhances the bioconversion of corn stover into ethanol

    PubMed Central

    2014-01-01

    Background Dry dilute acid pretreatment at extremely high solids loading of lignocellulose materials demonstrated promising advantages of no waste water generation, less sugar loss, and low steam consumption while maintaining high hydrolysis yield. However, the routine pretreatment reactor without mixing apparatus was found not suitable for dry pretreatment operation because of poor mixing and mass transfer. In this study, helically agitated mixing was introduced into the dry dilute acid pretreatment of corn stover and its effect on pretreatment efficiency, inhibitor generation, sugar production, and bioconversion efficiency through simultaneous saccharification and ethanol fermentation (SSF) were evaluated. Results The overall cellulose conversion taking account of cellulose loss in pretreatment was used to evaluate the efficiency of pretreatment. The two-phase computational fluid dynamics (CFD) model on dry pretreatment was established and applied to analyze the mixing mechanism. The results showed that the pretreatment efficiency was significantly improved and the inhibitor generation was reduced by the helically agitated mixing, compared to the dry pretreatment without mixing: the ethanol titer and yield from cellulose in the SSF reached 56.20 g/L and 69.43% at the 30% solids loading and 15 FPU/DM cellulase dosage, respectively, corresponding to a 26.5% increase in ethanol titer and 17.2% increase in ethanol yield at the same fermentation conditions. Conclusions The advantage of helically agitated mixing may provide a prototype of dry dilute acid pretreatment processing for future commercial-scale production of cellulosic ethanol. PMID:24387051

  2. Elder-clowning in long-term dementia care: Results of a pilot study

    PubMed Central

    Kontos, Pia; Miller, Karen-Lee; Colobong, Romeo; Lazgare, Luis Ivan Palma; Binns, Malcolm; Low, Lee-Fay; Surr, Claire; Naglie, Gary

    2016-01-01

    Objectives To assess the effects of elder-clowning on moderate to severe behavioral and psychological symptoms of dementia (BPSD) in nursing home residents with dementia, primarily of the Alzheimer’s type. Design Before-after study. Setting Nursing home. Participants Twenty-three nursing home residents with moderate to severe BPSD defined by the Neuropsychiatric Inventory-Nursing Home version (NPI-NH) score of ≥10, and their care aides. Intervention A pair of elder-clowns visited all residents twice weekly (approximately 10 minutes per visit) for 12 weeks. They utilized improvisation, humor and empathy, as well as expressive modalities such as song, musical instruments, and dance to individualize resident engagement. Measurements Primary outcomes were BPSD measured by the NPI-NH, quality of life measured by Dementia Care Mapping (DCM), and nursing burden of care measured by the Modified Nursing Care Assessment Scale (M-NCAS). Secondary outcomes included occupational disruptiveness measured by the NPI-NH, agitation measured by the Cohen Mansfield Agitation Inventory (CMAI), and psychiatric medication use. Results Over 12 weeks, NPI-NH scores significantly declined (t22 = −2.68, p = 0.01) and DCM quality of life scores significantly improved (F1,50 = 23.09, p < 0.001). CMAI agitation scores decreased nominally, but was not statistically significant (t22 = −1.86, p = 0.07). The occupational disruptiveness score significantly improved (t22 = −2.58, p = 0.02), yet there was no appreciable change in M-NCAS scores of staff burden of care. Conclusion Results suggest that elder-clowning reduced moderate to severe BPSD of nursing home residents with dementia, primarily of the Alzheimer’s type. Elder-clowning is a promising intervention that may improve Alzheimer’s dementia care for nursing home residents. PMID:26889843

  3. The Bayesian Inventory Problem

    DTIC Science & Technology

    1984-05-01

    Bayesian Approach to Demand Estimation and Inventory Provisioning," Naval Research Logistics Quarterly. Vol 20, 1973, (p607-624). 4 DeGroot , Morris H...page is blank APPENDIX A SUFFICIENT STATISTICS A convenient reference for moat of this material is DeGroot (41. Su-pose that we are sampling from a

  4. Digital Collections Inventory Report.

    ERIC Educational Resources Information Center

    McClung, Patricia A.

    This report is intended to inform and stimulate discussion on digital library programs as well as the potential usefulness, scope, and desired features of future inventories of online digital collections. It describes a joint project by the Commission on Preservation and Access and the Council on Library Resources to determine the extent to which…

  5. THE PRESCHOOL INVENTORY.

    ERIC Educational Resources Information Center

    CALDWELL, BETTYE M.; SOULE, DONALD

    THE PRESCHOOL INVENTORY BEGAN AS AN ANSWER TO THE NEED FOR SOME TYPE OF INSTRUMENT THAT WOULD PROVIDE AN INDICATION OF HOW MUCH A DISADVANTAGED CHILD, PRIOR TO HIS INTRODUCTION TO HEAD START, HAD ACHIEVED IN AREAS REGARDED AS NECESSARY FOUNDATIONS FOR SUBSEQUENT SUCCESS IN SCHOOL. MEASURING BASIC INTELLIGENCE WAS NOT THE GOAL. RATHER, THE…

  6. Pricing and Inventory Policies,

    DTIC Science & Technology

    The purpose of the research was to explore the feasibility of using profit rather than cost as the criteria for solving several traditional inventory...systems. The motivation for profit optimization is basic to theory of the firm. The underlying equation for this research is: Profit = Sales

  7. Marine Education Knowledge Inventory.

    ERIC Educational Resources Information Center

    Hounshell, Paul B.; Hampton, Carolyn

    This 35-item, multiple-choice Marine Education Knowledge Inventory was developed for use in upper elementary/middle schools to measure a student's knowledge of marine science. Content of test items is drawn from oceanography, ecology, earth science, navigation, and the biological sciences (focusing on marine animals). Steps in the construction of…

  8. Seafarers Knowledge Inventory.

    ERIC Educational Resources Information Center

    Hounshell, Paul B.

    This 60-item, multiple-choice Seafarers Knowledge Inventory was developed for use in marine vocational classes (grades 9-12) to measure a student's knowledge of information that "seafarers" should know. Items measure knowledge of various aspects of boating operation, weather, safety, winds, and oceanography. Steps in the construction of…

  9. Materials inventory management manual

    NASA Technical Reports Server (NTRS)

    1992-01-01

    This NASA Materials Inventory Management Manual (NHB 4100.1) is issued pursuant to Section 203(c)(1) of the National Aeronautics and Space Act of 1958 (42 USC 2473). It sets forth policy, performance standards, and procedures governing the acquisition, management and use of materials. This Manual is effective upon receipt.

  10. Mass Producing Concept Inventories

    NASA Astrophysics Data System (ADS)

    Garvin-Doxas, K.; Klymkowsky, M.; Doxas, I.

    2005-12-01

    Concept Inventories are research based assessment instruments which derive their validity and reliability from well researched distracters that represent students' dominant misconceptions in the field. They have formed the backbone of research based reform efforts in Physics by providing valid, reliable common assessment instruments with which to evaluate different teaching approaches and materials, and many disciplines are in the process of developing large numbers of Concept Inventories for their own subject areas. Unfortunately, Concept Inventories are labour and time intensive, with instruments taking anywhere from 2-8 years to develop, and correspondingly high price tags. The time and cost is directly related to the fact that valid, reliable instruments require mapping the dominant misconceptions in a field, which is usually a time consuming and labour intensive task. This paper will describe how we use Latent Semantic Analysis (LSA) with unsupervised clustering of the LSA vectors to identify and classify misconceptions in various science disciplines, considerably speeding up the process of misconception discovery and classification. The paper will present results from Astronomy and Biology, and will describe current efforts to develop a Concept Inventory for Space Physics.

  11. Explosive inventory program

    SciTech Connect

    Lewis, L.A.; Taylor, R.S.

    1990-09-01

    This report describes the computer program used at the Tonopah Test Range to maintain the explosive inventory. The program, which uses dBASE III or dBASE III Plus and runs on an IBM PC or compatible, has the capabilities to update (add or subtract) items, edit or delete, append, and generate various reports.

  12. "Leader Attributes Inventory" Manual.

    ERIC Educational Resources Information Center

    Moss, Jerome, Jr.; And Others

    This manual, which is designed to assist potential users of the Leader Attributes Inventory (LAI) and individuals studying leadership and its measurement, presents the rationale and psychometric characteristics of the LAI and guidelines for using it. Described in chapter 1 are the context in which the LAI was developed and the conceptualization of…

  13. Inventory Control and Purchasing.

    ERIC Educational Resources Information Center

    Nelson, Mason

    1981-01-01

    An inventory control system stimulates competitive bidding, resulting in the best price for an item. Other cost savings can be achieved by specifying prepayment of freight charges by the successful bidder, seeking standardization of products, and purchasing jointly with nearby municipalities and school districts. (Author/MLF)

  14. Student Attitude Inventory - 1971.

    ERIC Educational Resources Information Center

    Gillmore, Gerald M.; Aleamoni, Lawrence M.

    This 42-item Student Attitude Inventory (SAI) was administered to entering college freshmen at the University of Illinois (see TM 001 015). The SAI items are divided into nine categories on the basis of content as follows: voting behavior, drug usage, financial, Viet Nam war, education, religious behavior, pollution, housing, and alienation. A…

  15. Union Agitators

    ERIC Educational Resources Information Center

    Honawar, Vaishali

    2006-01-01

    A decade has passed since a few union leaders formed the network known as Teacher Union Reform Network (TURN) to search for innovative ways to enhance education. Selling their message has not always been easy. Created in 1995, TURN was the brain child of Adam Urbanski, the president of the Rochester (N.Y.) Teachers Association for the past 25…

  16. Granulation of core particles suitable for film coating by agitation fluidized bed III. Effect of scale, agitator rotational speed and blade shape on granule properties and development of a high accuracy scale-up theory.

    PubMed

    Hamashita, Tomohiro; Ono, Tetsuo; Ono, Masaki; Tsunenari, Yoshinobu; Aketo, Takao; Watano, Satoru

    2009-04-01

    The preparation of core particles suitable for subsequent film coating was examined using different scales of agitation fluidized beds. Specifically, the effects of agitator rotational speed and agitator blade shape in different scales of granulators on granule properties such as mass median diameter, apparent density, friability and shape factor were studied. As the agitator rotational speed was increased or when the agitator blade height and angle were large, the mass median diameter and friability of the granules decreased, while the apparent density and shape factor increased, in a manner independent of the vessel size because the granules were subjected to greater compression, shearing and rolling effects. The same core particles could not be prepared using granulators with different vessel sizes by simply adopting a conventional scale-up theory(1,2)) based on kinetic energy similarity. Here, a novel scale-up theory that takes into account agitator blade shape factors is proposed.(3)) When the two scale-up theories were compared, our new theory was capable of predicting the granule properties more accurately than the conventional theory. By adopting this novel theory, the same core particles could be prepared under different operating conditions in any scale of granulator.

  17. Inventory Systems Laboratory. Final Report.

    ERIC Educational Resources Information Center

    Naddor, Eliezer

    Four computer programs to aid students in understanding inventory systems, constructing mathematical inventory models, and developing optimal decision rules are presented. The program series allows a user to set input levels, simulates the behavior of major variables in inventory systems, and provides performance measures as output. Inventory…

  18. Toward an understanding of the effects of agitation and aeration on growth and laccases production by Pleurotus ostreatus.

    PubMed

    Tinoco-Valencia, Raunel; Gómez-Cruz, Cristina; Galindo, Enrique; Serrano-Carreón, Leobardo

    2014-05-10

    Mycelial growth and laccase production by Pleurotus ostreatus CP50 cultured in a 10-L mechanically agitated bioreactor were assessed through a 2(3) factorial experimental design. The main effects and interactions of three factors (agitation, aeration and copper induction) over five responses (μ, αLacc, βLacc, maximal volumetric laccase activity and maximal biomass concentration) were analyzed. P. ostreatus growth was significantly improved when culturing was conducted with high agitation (5.9kW/m(3)s) and aeration flow (0.5vvm) rates. Under the experimental conditions evaluated, no evidence of hydrodynamic stress affecting fungal growth was observed. However, the high agitation and aeration conditions were detrimental for the growth-associated laccase production constant (αLacc), leading to a very complex optimization of the process. The maximal laccase volumetric activity (1.2 and 3.8U/ml for non-induced and copper-induced cultures, respectively) was observed when the culturing was performed at a low agitation rate (0.9kW/m(3)s) and a high aeration flow rate (0.5vvm). Laccase proteolysis may explain the complex interactions observed between agitation and aeration and the effects of these factors on the laccase volumetric activity observed in the cultures.

  19. Detroit River habitat inventory

    USGS Publications Warehouse

    Manny, Bruce A.

    2003-01-01

    This inventory complements a previous survey of habitat in Ontario waters of the Detroit River (OMNR,1993). It is a starting point for balanced and sustained use of the river for natural resource conservation and economic development. The objectives of the inventory were to: (1) locate candidate sites for protection and restoration of fish and wildlife habitat in Michigan waters of the Detroit River; (2) describe the ownership and size of each site, as well as its potential for habitat protection and restoration; and (3) subjectively assess the extent to which existing habitat along the river is productive of fish and wildlife and protected from land uses that have degraded or destroyed such habitat.

  20. National Underground Mines Inventory

    DTIC Science & Technology

    1983-10-01

    that the contents necessaZiy reflect the views and policies of the Federal Emergency Management Agency. FINAL REPORT RTI/2506/OO-O1F NATIONAL...UNDERGROUND MINES INVENTORY Prepared by: M. Wright R. Chessin K. Reeves S. York, III Prepared for: Federal Emergency Management Agency Washington , D.C. 20472...Emergency Management Agency October 1983 Washington , DC 20472 I. NUMBEROFPAGES 80 14. MONITORING AGENCY NAME A ADORESS(1lierent bum Controflhi Office

  1. One size doesn't fit all: Should we reconsider the introduction of cold-stored platelets in blood bank inventories?

    PubMed

    Berzuini, Alessandra; Spreafico, Marta; Prati, Daniele

    2017-01-01

    Platelet concentrates are universally prepared with a standard method and stored for 5 days at room temperature (20-24°C) in gentle agitation. Currently, there is a renewed interest in the possibility of storing platelet concentrates below the standard temperatures. In fact, cold platelets might be more effective in bleeding patients and have a lower risk of bacterial transmission. Inventories including platelets at different temperatures may favour patient-centred strategies for prophylactic or therapeutic transfusions.

  2. One size doesn’t fit all: Should we reconsider the introduction of cold-stored platelets in blood bank inventories?

    PubMed Central

    Berzuini, Alessandra; Spreafico, Marta; Prati, Daniele

    2017-01-01

    Platelet concentrates are universally prepared with a standard method and stored for 5 days at room temperature (20–24°C) in gentle agitation. Currently, there is a renewed interest in the possibility of storing platelet concentrates below the standard temperatures. In fact, cold platelets might be more effective in bleeding patients and have a lower risk of bacterial transmission. Inventories including platelets at different temperatures may favour patient-centred strategies for prophylactic or therapeutic transfusions. PMID:28184297

  3. Dexmedetomidine Infusion to Control Agitation due to Anticholinergic Toxidromes in Adolescents, a Case Series

    PubMed Central

    Lin, Ada; Tobias, Joseph D.

    2015-01-01

    Dexmedetomidine is an α2-adrenergic agonist approved by the US Food and Drug Administration for the sedation of adults who are intubated on mechanical ventilation and in non-intubated adults who are undergoing surgical procedures. However, it has also recently become a commonly used sedative agent in varied clinical settings for the pediatric patient as well. We present the use of dexmedetomidine for sedation in a unique clinical scenario, the severely agitated and combative patient following the intentional misuse of anticholinergic drugs. Its applications in this situation are discussed, and previous reports in the literature are reviewed. PMID:26380573

  4. Methods for determining enzymatic activity comprising heating and agitation of closed volumes

    SciTech Connect

    Thompson, David Neil; Henriksen, Emily DeCrescenzo; Reed, David William; Jensen, Jill Renee

    2016-03-15

    Methods for determining thermophilic enzymatic activity include heating a substrate solution in a plurality of closed volumes to a predetermined reaction temperature. Without opening the closed volumes, at least one enzyme is added, substantially simultaneously, to the closed volumes. At the predetermined reaction temperature, the closed volumes are agitated and then the activity of the at least one enzyme is determined. The methods are conducive for characterizing enzymes of high-temperature reactions, with insoluble substrates, with substrates and enzymes that do not readily intermix, and with low volumes of substrate and enzyme. Systems for characterizing the enzymes are also disclosed.

  5. Treatment of post-electroconvulsive therapy delirium and agitation with donepezil.

    PubMed

    Logan, Christopher J; Stewart, Jonathan T

    2007-03-01

    Delirium and agitation are commonly encountered after administration of electroconvulsive therapy (ECT). Management is generally fairly straightforward, although some patients may have a severe, prolonged, or refractory course. We recently cared for a 65-year-old man who consistently developed severe and very prolonged post-ECT delirium that did not respond to typical pharmacological agents; the duration of delirium was dramatically shortened by the addition of donepezil. Cholinesterase inhibitors may have a place in mitigating severe and prolonged post-ECT delirium.

  6. Persistent genital arousal disorder: confluent patient history of agitated depression, paroxetine cessation, and a tarlov cyst.

    PubMed

    Eibye, Simone; Jensen, Hans Mørch

    2014-01-01

    We report a case of a woman suffering from persistent genital arousal disorder (PGAD) after paroxetine cessation. She was admitted to a psychiatric department and diagnosed with agitated depression. Physical investigation showed no gynaecological or neurological explanation; however, a pelvic MRI scan revealed a Tarlov cyst. Size and placement of the cyst could not explain the patient's symptoms; thus neurosurgical approach would not be helpful. Her depression was treated with antidepressant with little effect. Electroconvulsive therapy improved the patient's symptoms though they did not fully resolve. More awareness of PGAD and thorough interdisciplinary conferences are necessary to insure an unequivocal treatment strategy.

  7. Persistent Genital Arousal Disorder: Confluent Patient History of Agitated Depression, Paroxetine Cessation, and a Tarlov Cyst

    PubMed Central

    Jensen, Hans Mørch

    2014-01-01

    We report a case of a woman suffering from persistent genital arousal disorder (PGAD) after paroxetine cessation. She was admitted to a psychiatric department and diagnosed with agitated depression. Physical investigation showed no gynaecological or neurological explanation; however, a pelvic MRI scan revealed a Tarlov cyst. Size and placement of the cyst could not explain the patient's symptoms; thus neurosurgical approach would not be helpful. Her depression was treated with antidepressant with little effect. Electroconvulsive therapy improved the patient's symptoms though they did not fully resolve. More awareness of PGAD and thorough interdisciplinary conferences are necessary to insure an unequivocal treatment strategy. PMID:25525548

  8. Shear and mixing effects on cells in agitated microcarrier tissue culture reactors

    NASA Technical Reports Server (NTRS)

    Cherry, Robert S.; Papoutsakis, E. Terry

    1987-01-01

    Tissue cells are known to be sensitive to mechanical stresses imposed on them by agitation in bioreactors. The amount of agitation provided in a microcarrier or suspension bioreactor should be only enough to provide effective homogeneity. Three distinct flow regions can be identified in the reactor: bulk turbulent flow, bulk laminar flow and boundary-layer flows. Possible mechanisms of cell damage are examined by analyzing the motion of microcarriers or free cells relative to the surrounding fluid, to each other and to moving or stationary solid surfaces. The primary mechanisms of cell damage appear to result from: (1) direct interaction between microcarriers and turbulent eddies; (2) collisions between microcarriers in turbulent flow; and (3) collisions against the impeller or other stationary surfaces. If the smallest eddies of turbulent flow are of the same size as the microcarrier beads, they may cause high shear stresses on the cells. Eddies the size of the average interbead spacing may cause bead-bead collisions which damage cells. The severity of the collisions increases when the eddies are also of the same size as the beads. Impeller collisions occur when beads cannot avoid the impeller leading edge as it advances through the liquid. The implications of the results of this analysis on the design and operation of tissue culture reactors are discussed.

  9. [Current treatment of depression and agitation in the elderly -- clinical use of trazodone].

    PubMed

    Osváth, Péter

    2013-09-01

    Due to their increasing frequency, mental disorders among the elderly have special importance in the clinical practice. In this article we summarize the characteristics, diagnostic problems and modern treatments of mental disorders (especially depression) in old age. As this period of life means special somatic and psychic features in people's condition, it may be difficult to find the most effective and well-tolerated treatment, especially in case of comorbid dementia or agitated behaviour. In this article we review the therapeutic experience with the SARI antidepressant trazodone. Clinical studies and everyday practice indicate that trazodone due to its special multifunctional receptorprofile can be particularly effective in the treatment of depression accompanied by severe insomnia and anxiety. Due to its special anxiolytic and sleep normalising effect and well-tolerated side effect profile trazodone is found to be clinically useful not only in the treatment of depression in the elderly, but also in the case of serious comorbidity with dementia or agitated behaviour. We also illustrate the possibilities of using trazodone in the everyday practice with the presentation of two case reports. Furthermore we review the viewpoints of complex therapy which facilitates the successful treatment of depression in the elderly and the restoration of quality of life.

  10. Experimental study on agitated drying characteristics of sewage sludge under the effects of different additive agents.

    PubMed

    Deng, Wenyi; Su, Yaxin

    2014-07-01

    Drying experiments of dewatered sewage sludge (DSS) were conducted on a agitated paddle dryer, and the effects of additive agents, i.e., CaO, pulverized coal (PC), heavy oil (HO), and dried sludge ("DS" through back mixing) on the agitated drying characteristics of DSS were investigated. The results indicated that CaO can significantly increase the drying rate of DSS. The drying rate at CaO/DSS (mass ratio)=1/100 was 135% higher than that of CaO/DSS=0. Pulverized coal has no obvious effect on drying rate, but the increase of PC/DSS can promote breaking up of sludge lump. Heavy oil was found to be slightly effective in improving the drying rate of DSS in the examined experimental range of HO/DSS=0-1/20. It is also found that HO can reduce the torque of the dryer shaft, due to its lubrication effect. Back mixing of DS was found to be effective in alleviating the unfavorable effect of the lumpy phase by improving the mixing effect of the paddle dryer. There was a marked increase of drying rate with an increase of the DS/DSS in the experimental range of DS/DSS=0-1/3.

  11. Properties of a calicivirus isolated from cats dying in an agitated state.

    PubMed

    Sato, Y; Ohe, K; Fukuyama, M; Furuhata, K; Kishikawa, S; Sakai, S; Kiuchi, A; Hara, M; Watanabe, T; Ishikawa, Y; Taneno, A

    In June 1993, two of five pet cats kept in Yokohama city in Japan suddenly became agitated and died. Feline calicivirus (FCV) was isolated from them. One strain (FCV-S) was isolated from the spinal cord, lung and tonsil of cat 1, another (FCV-B) from the ileum, medulla oblongata and cervical spinal cord of cat 2, and a third (FCV-SAKURA) from the oral cavity of one of the three surviving cats which showed no clinical signs. These three strains were equally resistant to pH 3.0 and serologically similar to each other, but distinct from strain F9. A genetic analysis, using a 208 base pair fragment from region E of the capsid, showed that FCV-Ari had a 70.4 per cent nucleotide and 77.3 per cent amino acid homology and FCV-F9 had a 68.6 per cent nucleotide and 73.9 per cent amino acid homology with the three strains, indicating that these two strains were genetically distinct from the three new isolates. Unvaccinated cats and cats which had been vaccinated against FCV-F9 developed watery diarrhoea but did not become agitated after the administration of FCV-S. The FCV-S strain did not induce signs of excitability after it was administered orally to specific pathogen-free cats.

  12. Clinical monitoring scales in acute brain injury: assessment of coma, pain, agitation, and delirium.

    PubMed

    Riker, Richard R; Fugate, Jennifer E

    2014-12-01

    Serial clinical examination represents the most fundamental and basic form of neurological monitoring, and is often the first and only form of such monitoring in patients. Even in patients subjected to physiological monitoring using a range of technologies, the clinical examination remains an essential tool to follow neurological progress. Key aspects of the clinical examination have now been systematized into scoring schemes, and address consciousness, pain, agitation, and delirium (PAD). The Glasgow Coma Scale has been the traditional tool to measure consciousness, but the full outline of unresponsiveness (FOUR) score has recently been validated in a variety of settings, and at present, both represent clinically useful tools. Assessment of PAD in neurologically compromised patients present special challenges. For pain, the Numeric Rating Scale is the preferred initial approach, with either the Behavioral Pain Scale or the Critical Care Pain Observation Tool in subjects who are not able to respond. The Nociception Coma Scale-Revised may be useful in patients with severe disorders of consciousness. Conventional sedation scoring tools for critical care, such as the Richmond Area Sedation Scale (RASS) and Sedation-Agitation Scale (SAS) may provide reasonable tools in some neurocritical care patients. The use of sedative drugs and neuromuscular blockers may invalidate the use of some clinical examination tools in others. The use of sedation interruption to assess neurological status can result in physiological derangement in unstable patients (such as those with uncontrolled intracranial hypertension), and is not recommended.

  13. Hyperactivity with Agitative-Like Behavior in a Mouse Tauopathy Model.

    PubMed

    Jul, Pia; Volbracht, Christiane; de Jong, Inge E M; Helboe, Lone; Elvang, Anders Brandt; Pedersen, Jan Torleif

    2016-01-01

    Tauopathies, such as Alzheimer's disease (AD) and frontotemporal dementia (FTD), are characterized by formation of neurofibrillary tangles consisting of hyperphosphorylated tau. In addition to memory loss, patients experience behavioral symptoms such as agitation, aggression, depression, and insomnia. We explored the behavioral phenotype of a mouse model (rTg4510) carrying the human tau P301L mutation found in a familial form of FTD. We tested these mice in locomotor activity assays as well as in the Morris water maze to access spatial memory. In addition to cognitive impairments, rTg4510 mice exhibited a hyperactivity phenotype which correlated with progression of tau pathology and was dependent on P301L tau transgene expression. The hyperactive phenotype was characterized by significantly increased locomotor activity in a novel and in a simulated home cage environment together with a disturbed day/night cycle. The P301L-tau-dependent hyperactivity and agitative-like phenotype suggests that these mice may form a correlate to some of the behavioral disturbances observed in advanced AD and FTD.

  14. Rapid Tranquilization for Psychiatric Patients with Psychomotor Agitation: What is Known About it?

    PubMed

    de Almeida, Clayton Gonçalves; Del Grossi Moura, Mariana; Barberato-Filho, Silvio; de Sá Del Fiol, Fernando; Motta, Rogério Heládio Lopes; de Cássia Bergamaschi, Cristiane

    2017-03-09

    Rapid tranquilization is an intervention used in control of agitation or aggression in patients with mental disorders. This study synthesized the available evidence regarding efficacy and safety of drugs used for rapid tranquilization in psychiatric patients with psychomotor agitation. It is an overview study of systematic reviews and meta-analysis of randomized controlled trials (RCT) identified in the database MEDLINE, EMBASE, CINAHL, Web of Science, Cochrane Library and LILACS until April 2015. A team of reviewers, in pairs and independently, identified eligible studies and assessed methodological quality using AMSTAR. Data were extracted from four studies (61 RCT, 8021 participants). The association of haloperidol with promethazine (H + P) promoted tranquilization and presented better safety profile, with moderate quality evidence. Olanzapine demonstrated benefit towards tranquilization and good safety profile, but needed additional administration to keep tranquilization. There was no benefit in the use of haloperidol alone or associated to another psychotropic to most outcomes evaluated. The evidence was of low quality to most of the interventions. H + P was considered a good option for rapid tranquilization, however, more RCT are necessary to confirm the efficacy and safety of the available interventions.

  15. Effects of agitation on particle-size distribution and enzymatic hydrolysis of pretreated spruce and giant reed

    PubMed Central

    2014-01-01

    Background Mixing is an energy demanding process which has been previously shown to affect enzymatic hydrolysis. Concentrated biomass slurries are associated with high and non-Newtonian viscosities and mixing in these systems is a complex task. Poor mixing can lead to mass and/or heat transfer problems as well as inhomogeneous enzyme distribution, both of which can cause possible yield reduction. Furthermore the stirring energy dissipation may impact the particle size which in turn may affect the enzymatic hydrolysis. The objective of the current work was to specifically quantify the effects of mixing on particle-size distribution (PSD) and relate this to changes in the enzymatic hydrolysis. Two rather different materials were investigated, namely pretreated Norway spruce and giant reed. Results Changes in glucan hydrolysis and PSD were measured as a function of agitation during enzymatic hydrolysis at fiber loadings of 7 or 13% water-insoluble solids (WIS). Enzymatic conversion of pretreated spruce was strongly affected by agitation rates at the higher WIS content. However, at low WIS content the agitation had almost no effect on hydrolysis. There was some effect of agitation on the hydrolysis of giant reed at high WIS loading, but it was smaller than that for spruce, and there was no measurable effect at low WIS loading. In the case of spruce, intense agitation clearly affected the PSD and resulted in a reduced mean particle size, whereas for giant reed the decrease in particle size was mainly driven by enzymatic action. However, the rate of enzymatic hydrolysis was not increased after size reduction by agitation. Conclusions The impact of agitation on the enzymatic hydrolysis clearly depends not only on feedstock but also on the solids loading. Agitation was found to affect the PSD differently for the examined pretreated materials spruce and giant reed. The fact that the reduced mean particle diameter could not explain the enhanced hydrolysis rates found for

  16. Effect of Agitation on Acidogenesis Stage of Two-Stage Anaerobic Digestion of Palm Oil Mill Effluent (POME) into Biogas

    NASA Astrophysics Data System (ADS)

    Trisakti, B.; Irvan; Adipasah, H.; Taslim; Turmuzi, M.

    2017-03-01

    The acidogenesis stage in two-stage anaerobic digestion of palm oil mill effluent (POME) was studied in a continuous stirred tank reactor (CSTR). This research investigated the effect of agitation rate on the growth of microorganisms, the degradation of organic substances, and volatile fatty acids (VFA) production and composition. Initially, the suitable loading up was determined by varying the HRT 6.7, 5.0, and 4.0 days in a 2 L CSTR with agitation rate 50 rpm, pH 6.0 ± 0.2, at room temperature. Next, effect of agitation on the process was determined by varying agitation rate at 25, 50, 100, and 200 rpm. Analysis of total solids (TS), volatile solids (VS), total suspended solids (TSS), volatile suspended solids (VSS), chemical oxygen demand (COD), and volatile fatty acids (VFA) were conducted in order to study the growth of microorganisms and their abilities in converting organic compound to produce VFA. The highest growth of microorganisms was achieved at HRT 4.0 day with microorganism concentration was 20.62 mg VSS/L and COD reduction was 15.7%. The highest production of total VFA achieved was 5,766.61 mg/L mg/L at agitation rate 200 rpm, with concentration of acetic acid, propionic acid and butyric acid were 1,889.23; 1,161.43; and 2,725.95 mg/L, respectively. While degradation VS and COD were 16.61 and 38.79%.

  17. Six ways to reduce inventory.

    PubMed

    Lunn, T

    1996-05-01

    The purpose of this presentation is to help you reduce the inventory in your operation. We will accomplish that task by discussing six specific methods that companies have used successfully to reduce their inventory. One common attribute of these successes is that they also build teamwork among the people. Every business operation today is concerned with methods to improve customer service. The real trick is to accomplish that task without increasing inventory. We are all concerned with improving our skills at keeping inventory low.

  18. Inventory auditing: a manufacturing perspective.

    PubMed

    Swartley, J A; Hall, J D

    1990-08-01

    Despite the mystery that usually surrounds the annual audit program, its plan is easy to understand if you learn the basic concerns of the auditor. A five-step inventory audit plan usually consists of proving that the inventory exists, is completely represented, belongs to the firm, is properly valued, and is properly classified. To develop the inventory audit plan, an auditor must verify a firm's system of internal controls, in addition to verifying management's financial assertions by obtaining evidence about them. The time, cost, and frequency of the inventory audit with even the best plans may vary because of changing factors.

  19. Inventory of miscellaneous streams

    SciTech Connect

    Haggard, R.D.

    1998-08-14

    Miscellaneous streams discharging to the soil column on the Hanford Site are subject to requirements of several milestones identified in Consent Order No. DE 9INM-177 (Ecology and DOE 1991). The Plan and Schedule for Disposition and Regulatory Compliance for Miscellaneous Stream (DOE/RL-93-94) provides a plan and schedule for the disposition of miscellaneous streams to satisfy one of the Section 6.0 requirements of the Consent Order. One of the commitments (Activity 6-2.2) established in the plan and schedule is to annually update, the miscellaneous streams inventory. This document constitutes the 1998 revision of the miscellaneous streams inventory. Miscellaneous stream discharges were grouped into four permitting categories (Table 1). The first miscellaneous streams Permit (ST 4508) was issued May 30, 1997, to cover wastewater discharges from hydrotesting, maintenance, and construction activities. The second miscellaneous streams Permit (ST4509) covers discharges from cooling water and condensate discharges. The third permit application for category three waste streams was eliminated by recategorizing waste streams into an existing miscellaneous streams permit or eliminating stream discharges. Elimination of the third categorical permit application was approved by Ecology in January 1997 (Ecology 1997). The fourth permit application, to cover storm water, is due to Ecology in September 1998. Table 1 provides a history of the miscellaneous streams permitting activities.

  20. A simple collapse, agitation and pathological crying in a young woman? - Atypical onset of a basilar thrombosis

    PubMed Central

    Etgen, Thorleif; Milankovic-Eberl, Dragana; Rieder, Georg

    2014-01-01

    Background A collapse and agitation in a young person comprises many differential diagnoses, but usually does not include a life-threatening basilar thrombosis. Methods and Results We report the case of a 19-year old woman who presented mainly with a collapse and agitation. CT and CT-angiography yielded distal basilar thrombosis which was successfully treated by intraarterial thrombolysis. MRI confirmed multiple small ischemic lesions in the vertebrobasilar territory. The patient improved quickly and returned to her normal daily activities of life after a few months. Conclusions Posterior circulation ischemia should be included among the possible differential diagnoses of any acute onset of an agitated or confusional state. Conflicts of interest/Disclosures None to declare. Ethics Written informed consent of the patient has been obtained. PMID:25422712

  1. Paradoxical severe agitation induced by add-on high-doses quetiapine in schizo-affective disorder.

    PubMed

    Fond, Guillaume; MacGregor, Alexandra; Ducasse, Deborah; Brittner, Marie

    2014-05-15

    We report the case of a 35-year-old patient suffering from schizo-affective disorder since the age of 19 years, treated by a combination of first-generation antipsychotics, zuclopenthixol (100 mg/day) and lithium (1200 mg/day) (serum lithium=0.85 mEq/l). This patient had no associated personality disorder (particularly no antisocial disorder) and no substance abuse disorder. Within the 48 h following the gradual introduction of quetiapine (up to 600 mg/day), the patient presented severe agitation without an environmental explanation, contrasting with the absence of a history of aggressiveness or personality disorder. The diagnoses of manic shift and akathisia were dismissed. The withdrawal and the gradual reintroduction of quetiapine 2 weeks later, which led to another severe agitation, enabled us to attribute the agitation specifically to quetiapine.

  2. Effects of agitation speed on the ex vivo expansion of cord blood hematopoietic stem/progenitor cells in stirred suspension culture.

    PubMed

    Jing, Qiang; Cai, Haibo; Du, Zheng; Ye, Zhaoyang; Tan, Wen-song

    2013-04-01

    The mononuclear cells were cultivated in stirred flasks at different agitation speeds of 30 rpm, 45 rpm, 60 rpm and 80 rpm. At the agitation speed of 30 rpm, total cells achieved higher expansion folds and the CFC density increased. When at higher agitation speed of 60 rpm or 80 rpm, the number of cells dropped rapidly and characteristics of hematopoietic stem/progenitor cells (HSPCs) were not maintained. Moreover, the culture duration of 6-9 days was better for HSPCs ex vivo expansion. These data indicated that HSPCs should be cultured at relatively low agitation speed and for a short-term period when cultured in stirred suspension system.

  3. Controlling Inventory: Real-World Mathematical Modeling

    ERIC Educational Resources Information Center

    Edwards, Thomas G.; Özgün-Koca, S. Asli; Chelst, Kenneth R.

    2013-01-01

    Amazon, Walmart, and other large-scale retailers owe their success partly to efficient inventory management. For such firms, holding too little inventory risks losing sales, whereas holding idle inventory wastes money. Therefore profits hinge on the inventory level chosen. In this activity, students investigate a simplified inventory-control…

  4. 27 CFR 19.312 - Physical inventories.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Physical inventories. 19... Inventories § 19.312 Physical inventories. A proprietor must take a physical inventory of the spirits and... quarter. A proprietor must record the results of the inventory as provided in subpart V of this part...

  5. Dexmedetomidine Injection during Strabismus Surgery Reduces Emergence Agitation without Increasing the Oculocardiac Reflex in Children: A Randomized Controlled Trial

    PubMed Central

    Oh, Ah-Young; Baik, Ji-Seok; Kim, Jin Hee; Hwang, Jung- Won; Jeon, Young-Tae

    2016-01-01

    Objective Dexmedetomidine is known to reduce the incidence of emergence agitation, which is a common complication after inhalational anesthesia like sevoflurane or desflurane in children. However, the dose of dexmedetomidine used for this purpose is reported variously and the most effective dose is not known. In this study, we tried to find the most effective dose of dexmedetomidine to reduce the incidence of emergence agitation in children undergoing strabismus surgery without the complications like oculocardiac reflex (OCR) or postoperative vomiting. Methods We randomized 103 pediatric patients aged 2–6 years and undergoing elective strabismus surgery into four groups. Anesthesia was induced with sevoflurane and maintained with desflurane. At the start of induction, dexmedetomidine, delivered at 0.25, 0.5, or 1 μg/kg, or saline was infused intravenously in the D0.25, D0.5, D1 groups, respectively. The primary outcome measure was the incidence of emergence agitation and the secondary outcome measure was the incidence of intraoperative OCR, postoperative vomiting, and desaturation events. Results The incidence of emergence agitation was 60, 48, 44, and 21% (P = 0.005) and the incidence of intraoperative OCR was 36, 36, 36, and 37% (P = 0.988) in the control, D0.25, D0.5, and D1 groups, respectively. And, postoperative vomiting rate and desaturation events were low in the all groups. Conclusion Dexmedetomidine decreased the incidence of emergence agitation without increasing intraoperative oculocardiac reflex. Dexmedetomidine delivered at 1 μg/kg was more effective at reducing emergence agitation than lower doses in children undergoing strabismus surgery under desflurane anesthesia. Trial Registration Clinical Research Information Service KCT0000141 PMID:27617832

  6. The Role of Inhaled Loxapine in the Treatment of Acute Agitation in Patients with Psychiatric Disorders: A Clinical Review

    PubMed Central

    de Berardis, Domenico; Fornaro, Michele; Orsolini, Laura; Iasevoli, Felice; Tomasetti, Carmine; de Bartolomeis, Andrea; Serroni, Nicola; Valchera, Alessandro; Carano, Alessandro; Vellante, Federica; Marini, Stefano; Piersanti, Monica; Perna, Giampaolo; Martinotti, Giovanni; Di Giannantonio, Massimo

    2017-01-01

    Loxapine is a first generation antipsychotic, belonging to the dibenzoxazepine class. Recently, loxapine has been reformulated at a lower dose, producing an inhaled powder that can be directly administered to the lungs to treat the agitation associated with psychiatric disorders, such as schizophrenia and bipolar disorder. Thus, the aim of this narrative and clinical mini-review was to evaluate the efficacy and tolerability of inhaled loxapine in the treatment of acute agitation in patients with psychiatric disorders. The efficacy of inhaled loxapine has been evaluated in one Phase II trial on patients with schizophrenia, and in two Phase III trials in patients with schizophrenia and bipolar disorder. Moreover, there are two published case series on patients with borderline personality disorder and dual diagnosis patients. Inhaled loxapine has proven to be effective and generally well tolerated when administered to agitated patients with schizophrenia and bipolar disorder. Two case series have suggested that inhaled loxapine may also be useful to treat agitation in patients with borderline personality disorder and with dual diagnosis, but further studies are needed to clarify this point. However, the administration of inhaled loxapine requires at least some kind of patient collaboration, and is not recommended in the treatment of severe agitation in totally uncooperative patients. Moreover, the drug-related risk of bronchospasm must always be kept in mind when planning to use inhaled loxapine, leading to a careful patient assessment prior to, and after, administration. Also, the higher costs of inhaled loxapine, when compared to oral and intramuscular medications, should be taken into account when selecting it for the treatment of agitation. PMID:28208695

  7. Electroless deposition of nickel-boron coatings using low frequency ultrasonic agitation: Effect of ultrasonic frequency on the coatings.

    PubMed

    Bonin, L; Bains, N; Vitry, V; Cobley, A J

    2017-01-30

    The effect of ultrasound on the properties of Nickel-Boron (NiB) coatings was investigated. NiB coatings were fabricated by electroless deposition using either ultrasonic or mechanical agitation. The deposition of Ni occurred in an aqueous bath containing a reducible metal salt (nickel chloride), reducing agent (sodium borohydride), complexing agent (ethylenediamine) and stabilizer (lead tungstate). Due to the instability of the borohydride in acidic, neutral and slightly alkaline media, pH was controlled at pH 12±1 in order to avoid destabilizing the bath. Deposition was performed in three different configurations: one with a classical mechanical agitation at 300rpm and the other two employing ultrasound at a frequency of either 20 or 35kHz. The microstructures of the electroless coatings were characterized by a combination of optical Microscopy and Scanning Electron Microscope (SEM). The chemistry of the coatings was determined by ICP-AES (Inductively Coupled Plasma - Atomic Emission Spectrometry) after dissolution in aqua regia. The mechanical properties of the coatings were established by a combination of roughness measurements, Vickers microhardness and pin-on-disk tribology tests. Lastly, the corrosion properties were analysed by potentiodynamic polarization. The results showed that low frequency ultrasonic agitation could be used to produce coatings from an alkaline NiB bath and that the thickness of coatings obtained could be increased by over 50% compared to those produced using mechanical agitation. Although ultrasonic agitation produced a smoother coating and some alteration of the deposit morphology was observed, the mechanical and corrosion properties were very similar to those found when using mechanical agitation.

  8. Characterization of a continuous agitated cell reactor for oxygen dependent biocatalysis.

    PubMed

    Toftgaard Pedersen, Asbjørn; de Carvalho, Teresa Melo; Sutherland, Euan; Rehn, Gustav; Ashe, Robert; Woodley, John M

    2017-02-10

    Biocatalytic oxidation reactions employing molecular oxygen as the electron acceptor are difficult to conduct in a continuous flow reactor because of the requirement for high oxygen transfer rates. In this paper, the oxidation of glucose to glucono-1,5-lactone by glucose oxidase was used as a model reaction to study a novel continuous agitated cell reactor (ACR). The ACR consists of ten cells interconnected by small channels. An agitator is placed in each cell, which mixes the content of the cell when the reactor body is shaken by lateral movement. Based on tracer experiments, a hydrodynamic model for the ACR was developed. The model consisted of ten tanks-in-series with back-mixing occurring within and between each cell. The back-mixing was a necessary addition to the model in order to explain the observed phenomenon that the ACR behaved as two continuous stirred tank reactors (CSTRs) at low flow rates, while it at high flow rates behaved as the expected ten CSTRs in series. The performance of the ACR was evaluated by comparing the steady state conversion at varying residence times with the conversion observed in a stirred batch reactor of comparable size. It was found that the ACR could more than double the overall reaction rate, which was solely due to an increased oxygen transfer rate in the ACR caused by the intense mixing as a result of the spring agitators. The volumetric oxygen transfer coefficient, kL a, was estimated to be 344 h(-1) in the 100 mL ACR, opposed to only 104 h(-1) in a batch reactor of comparable working volume. Interestingly, the large deviation from plug flow behavior seen in the tracer experiments was found to have little influence on the conversion in the ACR, since both a plug flow reactor (PFR) model and the backflow cell model described the data sufficiently well. Biotechnol. Bioeng. 2017;9999: 1-9. © 2017 Wiley Periodicals, Inc.

  9. Successful treatment for psychomotor agitation in neuromyelitis optica spectrum disorder with trazodone-risperidone combination: a case report.

    PubMed

    Narita, Zui; Takano, Harumasa; Sumiyoshi, Tomiki

    2017-01-01

    Neuromyelitis optica (NMO) is a relapsing disease that typically affects the spinal cord and optic nerves. So far, a few studies have reported pharmacologic treatment for psychiatric symptoms in patients with NMO spectrum disorder (NMOSD). However, no literature has described psychomotor agitation associated with the disease and its treatment. We report an 84-year-old woman with NMOSD whose psychomotor agitation was effectively treated with a combination of trazodone and risperidone. Our observation suggests the ability of augmentation of antipsychotic drugs with antidepressants to ameliorate psychotic symptoms associated with NMOSD.

  10. The Effects of Nutrient Concentration, Addition of Thickeners, and Agitation Speed on Liquid Fermentation of Steinernema feltiae

    PubMed Central

    Leite, Luis G.; Shapiro-Ilan, David I.; Hazir, Selcuk; Jackson, Mark A.

    2016-01-01

    Entomopathogenic nematode production in liquid fermentation still requires improvements to maximize efficiency, yield, and nematode quality. Therefore, this study was aimed at developing a more suitable liquid medium for mass production of Steinernema feltiae, by assessing the effects of nutrient concentration, thickeners (primarily agar), and agitation speed on infective juvenile (IJ) yield. Base medium (BM) contained yeast extract (2.3%), egg yolk (1.25%), NaCl (0.5%), and corn oil (4%). All media were inoculated with Xenorhabdus bovienii, and 2 d later, with 2-d-old S. feltiae juveniles. For the nutrient concentration experiment, we evaluated the base medium versus a modified base medium containing all the components, but with 3× concentrations of yeast extract (6.9%), egg yolk (3.75%), and corn oil (12%). The nematodes and bacteria were cultured in 150-ml Erlenmeyer flasks containing 50 ml of liquid medium at (25°C) and 180 rpm on a rotary shaker incubator. To assess the effect of thickeners, IJs were inoculated in BM with agar (0.2%), carrageen (0.2%), and carboxymethyl cellulose (0.2% and 0.5%). The addition of 3× more nutrients relative to the BM resulted in a significantly lower yield of nematodes. For agar and agitation speed experiments, five levels of agar in the BM (0%, 0.2%, 0.4%, 0.6%, and 0.8% agar) and two agitation speeds (180 and 280 rpm) were evaluated for production. Increasing agitation speed from 180 to 280 rpm and higher levels of agar in the medium (> 0.2%) significantly increased the yield of bacteria. At the lower agitation speed, media amended with 0.4% and 0.6% agar produced higher nematode yields compared to media without agar. Media with 0.2% and 0.8% agar resulted in intermediate levels of nematode production. At the higher agitation speed, media supplemented with 0.8% agar resulted in the lowest yield of nematodes when compared to the other media tested. Results indicated that increasing nutrient concentration levels was

  11. Successful treatment for psychomotor agitation in neuromyelitis optica spectrum disorder with trazodone–risperidone combination: a case report

    PubMed Central

    Narita, Zui; Takano, Harumasa; Sumiyoshi, Tomiki

    2017-01-01

    Neuromyelitis optica (NMO) is a relapsing disease that typically affects the spinal cord and optic nerves. So far, a few studies have reported pharmacologic treatment for psychiatric symptoms in patients with NMO spectrum disorder (NMOSD). However, no literature has described psychomotor agitation associated with the disease and its treatment. We report an 84-year-old woman with NMOSD whose psychomotor agitation was effectively treated with a combination of trazodone and risperidone. Our observation suggests the ability of augmentation of antipsychotic drugs with antidepressants to ameliorate psychotic symptoms associated with NMOSD. PMID:28331329

  12. The Geist Picture Interest Inventory.

    ERIC Educational Resources Information Center

    Geist, Harold

    The purposes of this inventory are to: 1) assess quantitatively eleven male and twelve female general interest areas; 2) identify motivating forces behind occupational choice; 3) provide an interest inventory for working with those having limited verbal abilities; 4) provide possible additional information through projective uses; 5) further…

  13. Inventory behavior at remote sites

    NASA Technical Reports Server (NTRS)

    Lewis, William C., Jr.

    1987-01-01

    An operations research study was conducted concerning inventory behavior on the space station. Historical data from the Space Shuttle was used. The results demonstrated a high logistics burden if Space Shuttle reliability technology were to be applied without modification to space station design (which it was not). Effects of rapid resupply and on board repair capabilities on inventory behavior were investigated.

  14. NARSTO EMISSION INVENTORY WORKSHOP & ASSESSMENT

    EPA Science Inventory

    This presentation summarizes the NARSTO activities related to emission inventories in 2003-2005. The NARSTO Particulate Matter Assessment, issued in 2003, identified emission inventories as one of the critical elements of the air quality program which needs improvement if it i...

  15. Task Analysis Inventories. Series II.

    ERIC Educational Resources Information Center

    Wesson, Carl E.

    This second in a series of task analysis inventories contains checklists of work performed in twenty-two occupations. Each inventory is a comprehensive list of work activities, responsibilities, educational courses, machines, tools, equipment, and work aids used and the products produced or services rendered in a designated occupational area. The…

  16. Automation of Space Inventory Management

    NASA Technical Reports Server (NTRS)

    Fink, Patrick W.; Ngo, Phong; Wagner, Raymond; Barton, Richard; Gifford, Kevin

    2009-01-01

    This viewgraph presentation describes the utilization of automated space-based inventory management through handheld RFID readers and BioNet Middleware. The contents include: 1) Space-Based INventory Management; 2) Real-Time RFID Location and Tracking; 3) Surface Acoustic Wave (SAW) RFID; and 4) BioNet Middleware.

  17. Computer program determines inventory size

    NASA Technical Reports Server (NTRS)

    Kaspar, H.

    1966-01-01

    FORTRAN 4 computer program calculates optimum size of a small inventory of relatively complex or expensive items. This program can be used in situations where the initial cost of purchase is large or when there is a need for a balanced inventory on a short production run.

  18. Student-Life Stress Inventory.

    ERIC Educational Resources Information Center

    Gadzella, Bernadette M.; And Others

    The reliability of the Student-Life Stress Inventory of B. M. Gadzella (1991) was studied. The inventory consists of 51 items listed in 9 sections indicating different types of stressors (frustrations, conflicts, pressures, changes, and self-imposed stressors) and reactions to the stressors (physiological, emotional, behavioral, and cognitive) as…

  19. National Mobile Inventory Model (NMIM)

    EPA Pesticide Factsheets

    The National Mobile Inventory Model (NMIM) is a free, desktop computer application developed by EPA to help you develop estimates of current and future emission inventories for on-road motor vehicles and nonroad equipment. To learn more search the archive

  20. Indian scales and inventories

    PubMed Central

    Venkatesan, S.

    2010-01-01

    This conceptual, perspective and review paper on Indian scales and inventories begins with clarification on the historical and contemporary meanings of psychometry before linking itself to the burgeoning field of clinimetrics in their applications to the practice of clinical psychology and psychiatry. Clinimetrics is explained as a changing paradigm in the design, administration, and interpretation of quantitative tests, techniques or procedures applied to measurement of clinical variables, traits and processes. As an illustrative sample, this article assembles a bibliographic survey of about 105 out of 2582 research papers (4.07%) scanned through 51 back dated volumes covering 185 issues related to clinimetry as reviewed across a span of over fifty years (1958-2009) in the Indian Journal of Psychiatry. A content analysis of the contributions across distinct categories of mental measurements is explained before linkages are proposed for future directions along these lines. PMID:21836709

  1. National Wetlands Inventory products

    USGS Publications Warehouse

    ,

    1998-01-01

    control. These predominantly wet areas, or wetlands as they are commonly called, now represent only about 5 percent of the land surface of the lower 48 States. Out of 221 million acres of wetlands that once existed in the conterminous United States, the U.S. Fish and Wildlife Service (FWS) estimates that only about 103.3 million acres remain. Each year, development, drainage, and agriculture eliminate another 290,000 acres-an area a little less than half the size of Rhode Island. From the 1950's to the 1970's, conversion of wetlands to farmland caused 87 percent of all wetland losses. The FWS has long recognized the importance of America's wetlands because they form breeding and wintering grounds for great numbers of migratory birds. In 1977, the FWS began the National Wetlands Inventory (NWI), a systematic effort to classify and map America's remaining wetlands.

  2. Assessment of Electromagnetic Stirrer Agitated Liquid Metal Flows by Dynamic Neutron Radiography

    NASA Astrophysics Data System (ADS)

    Ščepanskis, Mihails; Sarma, Mārtiņš; Vontobel, Peter; Trtik, Pavel; Thomsen, Knud; Jakovičs, Andris; Beinerts, Toms

    2017-01-01

    This paper presents qualitative and quantitative characterization of two-phase liquid metal flows agitated by the stirrer on rotating permanent magnets. The stirrer was designed to fulfill various eddy flows, which may have different rates of solid particle entrapment from the liquid surface and their homogenization. The flow was characterized by visualization of the tailored tracer particles by means of dynamic neutron radiography, an experimental method well suited for liquid metal flows due to low opacity of some metals for neutrons. The rather high temporal resolution of the image acquisition (32 Hz image acquisition rate) allows for the quantitative investigation of the flows up to 30 cm/s using neutron particle image velocimetry. In situ visualization of the two-phase liquid metal flow is also demonstrated.

  3. Assessment of Electromagnetic Stirrer Agitated Liquid Metal Flows by Dynamic Neutron Radiography

    NASA Astrophysics Data System (ADS)

    Ščepanskis, Mihails; Sarma, Mārtiņš; Vontobel, Peter; Trtik, Pavel; Thomsen, Knud; Jakovičs, Andris; Beinerts, Toms

    2017-04-01

    This paper presents qualitative and quantitative characterization of two-phase liquid metal flows agitated by the stirrer on rotating permanent magnets. The stirrer was designed to fulfill various eddy flows, which may have different rates of solid particle entrapment from the liquid surface and their homogenization. The flow was characterized by visualization of the tailored tracer particles by means of dynamic neutron radiography, an experimental method well suited for liquid metal flows due to low opacity of some metals for neutrons. The rather high temporal resolution of the image acquisition (32 Hz image acquisition rate) allows for the quantitative investigation of the flows up to 30 cm/s using neutron particle image velocimetry. In situ visualization of the two-phase liquid metal flow is also demonstrated.

  4. Remediating agitation-induced antibody aggregation by eradicating exposed hydrophobic motifs

    PubMed Central

    Clark, Rutilio H; Latypov, Ramil F; De Imus, Cyr; Carter, Jane; Wilson, Zien; Manchulenko, Kathy; Brown, Michael E; Ketchem, Randal R

    2014-01-01

    Therapeutic antibodies must encompass drug product suitable attributes to be commercially marketed. An undesirable antibody characteristic is the propensity to aggregate. Although there are computational algorithms that predict the propensity of a protein to aggregate from sequence information alone, few consider the relevance of the native structure. The Spatial Aggregation Propensity (SAP) algorithm developed by Chennamsetty et. al. incorporates structural and sequence information to identify motifs that contribute to protein aggregation. We have utilized the algorithm to design variants of a highly aggregation prone IgG2. All variants were tested in a variety of high-throughput, small-scale assays to assess the utility of the method described herein. Many variants exhibited improved aggregation stability whether induced by agitation or thermal stress while still retaining bioactivity. PMID:25484048

  5. Genetic transformation of Platymonas ( Tetraselmis) subcordiformis (Prasinophyceae, Chlorophyta) using particle bombardment and glass-bead agitation

    NASA Astrophysics Data System (ADS)

    Cui, Yulin; Jiang, Peng; Wang, Jinfeng; Li, Fuchao; Chen, Yingjie; Zheng, Guoting; Qin, Song

    2012-05-01

    Platymonas ( Tetraselmis) subcordiformis is a unicellular marine green alga. It was found to be very sensitive to the herbicide Basta through a sensitivity test indicating it could be employed as a selective agent. The bar gene is a practicable and selectable marker gene. The vector containing the expression cassette of the bar gene was transferred to P. subcordiformis by both particle bombardment and glass-bead agitation and transformants were then selected using Basta. Finally, Southern blotting analysis indicated that the bar gene had been successfully integrated into the nuclear genome of P. subcordiformis using both of the transgenic techniques, with the transformation efficiency of the glass-bead method being slightly higher than that of particle bombardment. This is the first report on stable transformation of P. subcordiformis, and will improve fundamental research and enlarge application of this alga.

  6. Reactor concepts for atomic layer deposition on agitated particles: A review

    SciTech Connect

    Longrie, Delphine Deduytsche, Davy; Detavernier, Christophe

    2014-01-15

    The number of possible applications for nanoparticles has strongly increased in the last decade. For many applications, nanoparticles with different surface and bulk properties are necessary. A popular surface modification technique is coating the particle surface with a nanometer thick layer. Atomic layer deposition (ALD) is known as a reliable method for depositing ultrathin and conformal coatings. In this article, agitation or fluidization of the particles is necessary for performing ALD on (nano)particles. The principles of gas fluidization of particles will be outlined, and a classification of the gas fluidization behavior of particles based on their size and density will be given. Following different reactor concepts that have been designed to conformally coat (nano)particles with ALD will be described, and a concise overview will be presented of the work that has been performed with each of them ending with a concept reactor for performing spatial ALD on fluidized particles.

  7. Theoretical estimate of the effect of thermal agitation on ribosome motion generated by stochastic microswimming.

    PubMed

    González-García, José S

    2016-11-04

    The effect of thermal agitation on ribosome motion is evaluated through the Péclet number, assuming that the ribosome is self-propelled along the mRNA during protein synthesis by a swimming stroke consisting of a cycle of stochastically-generated ribosome configurations involving its two subunits. The ribosome velocity probability distribution function is obtained, giving an approximately normal distribution. Its mean and variance together with an estimate of the in vivo free diffusion coefficient of the ribosome and using only configuration changes of small size, give a Péclet number similar to motor proteins and microorganisms. These results suggest the feasibility of the stochastic microswimming hypothesis to explain ribosome motion.

  8. Reducing fischer-tropsch catalyst attrition losses in high agitation reaction systems

    DOEpatents

    Singleton, Alan H.; Oukaci, Rachid; Goodwin, James G.

    2001-01-01

    A method for reducing catalyst attrition losses in hydrocarbon synthesis processes conducted in high agitation reaction systems; a method of producing an attrition-resistant catalyst; a catalyst produced by such method; a method of producing an attrition-resistant catalyst support; and a catalyst support produced by such method. The inventive method of reducing catalyst attrition losses comprises the step of reacting a synthesis gas in a high agitation reaction system in the presence of a catalyst. In one aspect, the catalyst preferably comprises a .gamma.-alumina support including an amount of titanium effective for increasing the attrition resistance of the catalyst. In another aspect, the catalyst preferably comprises a .gamma.-alumina support which has been treated, after calcination, with an acidic, aqueous solution. The acidic aqueous solution preferably has a pH of not more than about 5. In another aspect, the catalyst preferably comprises cobalt on a .gamma.-alumina support wherein the cobalt has been applied to the .gamma.-alumina support by totally aqueous, incipient wetness-type impregnation. In another aspect, the catalyst preferably comprises cobalt on a .gamma.-alumina support with an amount of a lanthana promoter effective for increasing the attrition resistance of the catalyst. In another aspect, the catalyst preferably comprises a .gamma.-alumina support produced from boehmite having a crystallite size, in the 021 plane, in the range of from about 30 to about 55 .ANG.ngstrons. In another aspect, the inventive method of producing an attrition-resistant catalyst comprises the step of treating a .gamma.-alumina support, after calcination of and before adding catalytic material to the support, with an acidic solution effective for increasing the attrition resistance of the catalyst. In another aspect, the inventive method of producing an attrition-resistant catalyst support comprises the step of treating calcined .gamma.-alumina with an acidic, aqueous

  9. A comparison of postoperative emergence agitation between sevoflurane and thiopental anesthesia induction in pediatric patients

    PubMed Central

    Son, Ji-Seon; Jang, Eunjoo; Oh, Min Wook; Lee, Ji-Hye; Han, Young Jin

    2015-01-01

    Background This study was performed to compare the incidence of emergence agitation (EA) between inhalation and intravenous anesthesia induction in children after sevoflurane anesthesia. Methods In this prospective and double-blind study, 100 children aged 3 to 7 years were enrolled. Subjects were randomly assigned to the sevoflurane (Group S) or thiopental (Group T) anesthesia induction groups. Anesthesia was induced using 8% sevoflurane and 4-6 mg/kg thiopental in Groups S and T, respectively. Anesthesia was maintained with nitrous oxide and sevoflurane. The children were evaluated at 5 and 20 min after arrival in the postanesthesia care unit (PACU) with a four-point agitation scale and the Pediatric Anesthesia Emergence Delirium scale. The incidence of EA and administration of the rescue agent were recorded. Results The incidence of EA was significantly lower in Group T compared to Group S at 5 min after PACU arrival (3/49 patients, 6% vs. 12/47 patients, 26%, P = 0.019). However, there was no difference between the two groups at 20 min after PACU arrival (23/49 vs. 19/47 patients in Group T vs. Group S, P = 0.425). The overall incidence of EA was 60% (28/47 patients) in Group S and 41% (20/49 patients) in Group T (P = 0.102). The number of children who received propofol as a rescue agent was significantly lower in Group T (Group S: 14/47 vs. Group T: 5/49, P = 0.031). Conclusions Intravenous anesthesia induction with thiopental reduced the incidence of EA in the early PACU period compared to inhalation induction with sevoflurane in 3- to 7-year-old children undergoing sevoflurane anesthesia. PMID:26257850

  10. Impact of pharmaceutical care on pain and agitation in a medical intensive care unit in Thailand.

    PubMed

    Dilokpattanamongkol, Pitchaya; Tangsujaritvijit, Viratch; Suansanae, Thanarat; Suthisisang, Chuthamanee

    2017-03-29

    Background Currently, a lack of pharmaceutical care exists concerning pain and agitation in medical intensive care units (MICU) in Thailand. Pharmaceutical care focusing on analgesics/sedatives would improve clinical outcomes. Objective To investigate the impact of pharmaceutical care of pain and agitation on ICU length of stay (LOS), hospital LOS, ventilator days and mortality. Setting The MICU of a university hospital. Method A before/after study was conducted on mechanically ventilated patients receiving analgesics/sedatives. Medical chart reviews and data collection were conducted in the retrospective group (no pharmacists involved). In the prospective group, pharmacists involved with the critical care team helped select analgesics/sedatives for individual patients. Main outcome measure ICU LOS Results In total, 90 and 66 patients were enrolled in retrospective and prospective groups, respectively. The median duration of ICU LOS was reduced from 10.00 (2.00-72.00) in the retrospective group to 6.50 days (2.00-30.00) in the prospective group (p = 0.002). The median hospital stay was reduced from 30.50 days (2.00-119.00) in the retrospective group to 17.50 days (2.00-110.00) in the prospective group (p < 0.001). Also, the median ventilator days was reduced from 14.00 days (2.00-90.00) to 8.50 days (1.00-45.00), p = 0.008. Mortality was 53.03% in the prospective group and 46.67% in the retrospective group (p = 0.432). Conclusion Pharmacist participation in a critical care team resulted in a significant reduction in the duration of ICU LOS, hospital LOS and ventilator days, but not mortality.

  11. Entropy correlates with Richmond Agitation Sedation Scale in mechanically ventilated critically ill patients.

    PubMed

    Sharma, Ankur; Singh, Preet Mohinder; Trikha, Anjan; Rewari, Vimi; Chandralekha

    2014-04-01

    Sedation is routinely used in intensive care units. However due to absence of objective scoring systems like Bispectral Index and entropy our ability to regulate the degree of sedation is limited. This deficiency is further highlighted by the fact that agitation scores used in intensive care units (ICU) have no role in paralyzed patients. The present study compares entropy as a sedation scoring modality with Richmond Agitation Sedation Scale (RASS) in mechanically ventilated, critically ill patients in an ICU. Twenty-seven, mechanically ventilated, critically ill patients of either sex, 16-65 years of age, were studied over a period of 24 h. They received a standard sedation regimen consisting of a bolus dose of propofol 0.5 mg/kg and fentanyl 1 lg/kg followed by infusions of propofol and fentanyl ranging from 1.5 to 5 mg/kg/h and 0.5 to 2.0 lg/kg/h, respectively. Clinically relevant values of RASS for optimal ICU sedation (between 0 and -3) in non-paralyzed patients were compared to corresponding entropy values, to find if any significant correlation exists between the two. These entropy measurements were obtained using the Datex-Ohmeda-M-EntropyTM module. This module is presently not approved by Food and Drug Administration (FDA) for monitoring sedation in ICU. A total of 527 readings were obtained. There was a statistically significant correlation between the state entropy (SE) and RASS [Spearman's rho/rs = 0.334, p\\0.0001]; response entropy (RE) and RASS [Spearman's rho/rs = 0.341, p\\0.0001]). For adequate sedation as judged by a RASS value of 0 to -3, the mean SE was 57.86 ± 16.50 and RE was 67.75 ± 15.65. The present study illustrates that entropy correlates with RASS (between scores 0 and -3) when assessing the level of sedation in mechanically ventilated critically ill patients.

  12. Nonthermal microwave effects revisited: on the importance of internal temperature monitoring and agitation in microwave chemistry.

    PubMed

    Herrero, M Antonia; Kremsner, Jennifer M; Kappe, C Oliver

    2008-01-04

    The concept of nonthermal microwave effects has received considerable attention in recent years and is the subject of intense debate in the scientific community. Nonthermal microwave effects have been postulated to result from a direct stabilizing interaction of the electric field with specific (polar) molecules in the reaction medium that is not related to a macroscopic temperature effect. In order to probe the existence of nonthermal microwave effects, four synthetic transformations (Diels-Alder cycloaddition, alkylation of triphenylphosphine and 1,2,4-triazole, direct amide bond formation) were reevaluated under both microwave dielectric heating and conventional thermal heating. In all four cases, previous studies have claimed the existence of nonthermal microwave effects in these reactions. Experimentally, significant differences in conversion and/or product distribution comparing the conventionally and microwave-heated experiments performed at the same measured reaction temperature were found. The current reevaluation of these reactions was performed in a dedicated reactor setup that allowed accurate internal reaction temperature measurements using a multiple fiber-optic probe system. Using this technology, the importance of efficient stirring and internal temperature measurement in microwave-heated reactions was made evident. Inefficient agitation leads to temperature gradients within the reaction mixture due to field inhomogeneities in the microwave cavity. Using external infrared temperature sensors in some cases results in significant inaccuracies in the temperature measurement. Applying the fiber-optic probe temperature monitoring device, a critical reevaluation of all four reactions has provided no evidence for the existence of nonthermal microwave effects. Ensuring efficient agitation of the reaction mixture via magnetic stirring, no significant differences in terms of conversion and selectivity between experiments performed under microwave or oil bath

  13. 48 CFR 245.606 - Inventory schedules.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Inventory schedules. 245.606 Section 245.606 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... Contractor Inventory 245.606 Inventory schedules....

  14. Effect of thermal agitation on the switching field distributions of CoPtCr-SiO2 perpendicular recording media

    NASA Astrophysics Data System (ADS)

    Shimatsu, T.; Kondo, T.; Mitsuzuka, K.; Watanabe, S.; Aoi, H.; Muraoka, H.; Nakamura, Y.

    2006-04-01

    The effect of thermal agitations on the switching field distribution (SFD) of CoPtCr-SiO2 perpendicular media was investigated. Dc demagnetizing (DCD) magnetization curves and minor dc demagnetizing (M-DCD) magnetization curves were measured at applied field sweep rates of ~10 and ~108 Oe/s. We estimated the SFD from the difference between the DCD and M-DCD curves, and defined them as ΔHr/Hr (at ~10 Oe/s) and ΔHrP/HrP (at ~108 Oe/s). The values of ΔHrP/HrP were found to be 60%-70% of ΔHr/Hr. The difference between ΔHrP/HrP and ΔHr/Hr should be caused by thermal agitation of the magnetization. The influence of the distribution of the thermal agitation on SFD was calculated using the distribution of the grain volumes. It is concluded that the SFD measured at vibrating-sample magnetometer (VSM) time scales is significantly influenced by thermal agitation of the magnetization, and reduction of the grain size distribution is the most effective way to reduce the SFD at VSM time scales.

  15. Music therapy: A nonpharmacological approach to the care of agitation and depressive symptoms for nursing home residents with dementia.

    PubMed

    Ray, Kendra D; Mittelman, Mary S

    2015-10-29

    Depression, agitation, and wandering are common behaviors associated with dementia and frequently observed among nursing home residents. Even with pharmacological treatment, behaviors often persist, hindering quality of life for elders, their family, and paid caregivers. This study examined the use of music therapy for treatment of these symptoms among 132 people with moderate to severe dementia in nursing homes. Participants were evaluated for depressive symptoms, agitation, and wandering to determine their predominate behavior. There were two assessments, two weeks apart, prior to intervention, followed by a two-week intervention, and two follow-up assessments, also two weeks apart. A repeated measures ANOVA determined that after two weeks of music therapy, symptoms of depression and agitation were significantly reduced; there was no change for wandering. Multivariate analyses confirmed a relationship between music therapy and change in neuropsychiatric symptoms associated with dementia. Results suggest widespread use of music therapy in long-term care settings may be effective in reducing symptoms of depression and agitation.

  16. How to Radicalize Graduate Students: Take These Simple Steps to Intimidate, Alienate, and Agitate Your Own Flock of Graduate Students

    ERIC Educational Resources Information Center

    Steffen, Heather

    2011-01-01

    As the recession, budget cuts, endowment losses, and Republican governors gut university funding, campuses across the country have become host to occupations, union actions, and demonstrations. One can take steps to intimidate, alienate, and agitate a flock of graduate students. The author discusses steps that offer simple ways to rile up and…

  17. Investigating the influence of pH, temperature and agitation speed on yellow pigment production by Penicillium aculeatum ATCC 10409.

    PubMed

    Afshari, Majid; Shahidi, Fakhri; Mortazavi, Seyed Ali; Tabatabai, Farideh; Es'haghi, Zarin

    2015-01-01

    In this study, the combined effect of pH, temperature and agitation speed on yellow pigment production and mycelial growth of Penicillium aculeatum ATCC 10409 was investigated in whey media. Different pH levels (5, 6.5 and 8), temperatures (25, 30 and 35°C) and agitation speed levels (100 and 150 rpm) were tested to determine the best conditions to produce a fungal yellow pigment under submerged fermentation. The best production of yellow pigment (1.38 g/L) was obtained with a pH value of 6.5, a temperature of 30°C and an agitation speed of 150 rpm. In contrast, the maximal biomass concentration (11.12 g/L) was obtained at pH value of 8, a temperature of 30°C and an agitation speed of 100 rpm. These results demonstrated that biomass and yellow pigment production were not directly associated. The identification of the structure of unknown P. aculeatum yellow pigment was detected using UV absorption spectrum and FT-IR spectroscopy.

  18. The effects of nutrient concentration, addition of thickeners, and agitation speed on liquid fermentation of Steinernema feltiae

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Therefore, this study was aimed at developing a more suitable liquid media for mass production of Steinernema feltiae, by assessing the effects of nutrient concentration, media viscosity, and agitation speed on infective juvenile (IJ) yield. For all the experiments, the base medium contained yeast ...

  19. Communication Capacity Scale and Agitation Distress Scale to measure the severity of delirium in terminally ill cancer patients: a validation study.

    PubMed

    Morita, T; Tsunoda, J; Inoue, S; Chihara, S; Oka, K

    2001-05-01

    Although valid measurement of the severity of terminal delirium is of great importance in palliative care settings, existing instruments have considerable limitations. In order to quantify patients' communication capacity and agitated behaviour, two new operational observer-rating scales, the Communication Capacity Scale (Communication Scale) and Agitation Distress Scale (Agitation Scale), were validated. Thirty terminally ill cancer patients diagnosed with delirium were evaluated simultaneously by two palliative care physicians blinded to each other's coding using the Communication Scale and Agitation Scale. In addition, the Memorial Delirium Assessment Scale (MDAS), Delirium Rating Scale (DRS) and Sedation Scale were rated by one researcher. Both scales achieved high internal consistency and inter-rater reliability with Cronbach's alpha coefficients of 0.91 and 0.96, and Cohen's kappa values on each item of 0.72-1.00. The principal components analysis resulted in the emergence of only one component for each scale. The total score on the Communication Scale was highly associated with that of the MDAS (rho = 0.78), Sedation Scale (rho = 0.86), and cognitive items from the MDAS and DRS (rho = 0.83). The whole score on the Agitation Scale was significantly correlated with that of the DRS (rho = 0.61) and agitation items from the MDAS and DRS (rho = 0.61). In conclusion, the Communication Scale and Agitation Scale have acceptable reliability and validity to quantify patients' communication capacity and agitation symptoms of terminally ill cancer patients with delirium.

  20. INEEL Liquid Effluent Inventory

    SciTech Connect

    Major, C.A.

    1997-06-01

    The INEEL contractors and their associated facilities are required to identify all liquid effluent discharges that may impact the environment at the INEEL. This liquid effluent information is then placed in the Liquid Effluent Inventory (LEI) database, which is maintained by the INEEL prime contractor. The purpose of the LEI is to identify and maintain a current listing of all liquid effluent discharge points and to identify which discharges are subject to federal, state, or local permitting or reporting requirements and DOE order requirements. Initial characterization, which represents most of the INEEL liquid effluents, has been performed, and additional characterization may be required in the future to meet regulations. LEI information is made available to persons responsible for or concerned with INEEL compliance with liquid effluent permitting or reporting requirements, such as the National Pollutant Discharge Elimination System, Wastewater Land Application, Storm Water Pollution Prevention, Spill Prevention Control and Countermeasures, and Industrial Wastewater Pretreatment. The State of Idaho Environmental Oversight and Monitoring Program also needs the information for tracking liquid effluent discharges at the INEEL. The information provides a baseline from which future liquid discharges can be identified, characterized, and regulated, if appropriate. The review covered new and removed buildings/structures, buildings/structures which most likely had new, relocated, or removed LEI discharge points, and at least 10% of the remaining discharge points.

  1. Inventory of miscellaneous streams

    SciTech Connect

    Lueck, K.J.

    1995-09-01

    On December 23, 1991, the US Department of Energy, Richland Operations Office (RL) and the Washington State Department of Ecology (Ecology) agreed to adhere to the provisions of the Department of Ecology Consent Order. The Consent Order lists the regulatory milestones for liquid effluent streams at the Hanford Site to comply with the permitting requirements of Washington Administrative Code. The RL provided the US Congress a Plan and Schedule to discontinue disposal of contaminated liquid effluent into the soil column on the Hanford Site. The plan and schedule document contained a strategy for the implementation of alternative treatment and disposal systems. This strategy included prioritizing the streams into two phases. The Phase 1 streams were considered to be higher priority than the Phase 2 streams. The actions recommended for the Phase 1 and 2 streams in the two reports were incorporated in the Hanford Federal Facility Agreement and Consent Order. Miscellaneous Streams are those liquid effluents streams identified within the Consent Order that are discharged to the ground but are not categorized as Phase 1 or Phase 2 Streams. This document consists of an inventory of the liquid effluent streams being discharged into the Hanford soil column.

  2. National Wetlands Inventory products

    USGS Publications Warehouse

    ,

    1999-01-01

    Marshes, swamps, ponds, and bogs are teeming biological nurseries for migratory birds, fish, and aquatic plants. They also provide natural flood and erosion control. These predominantly wet areas, or wetlands as they are commonly called, now represent only about 5 percent of the land surface of the lower 48 States. Out of 221 million acres of wetlands that once existed in the conterminous United States, the U.S. Fish and Wildlife Service (FWS) estimates that only about 103.3 million acres remain. Each year, development, drainage, and agriculture eliminate another 290,000 acres - an area a little less than half the size of Rhode Island. From the 1950's to the 1970's, conversion of wetlands to farmland caused 87 percent of all wetland losses. The FWS has long recognized the importance of America's wetlands because they form breeding and wintering grounds for great numbers of migratory birds. In 1977, the FWS began the National Wetlands Inventory (NWI), a systematic effort to classify and map America's remaining wetlands.

  3. Utilizing the Advisor Perception Inventory.

    ERIC Educational Resources Information Center

    Ford, Jerry

    1985-01-01

    In order to help assess the effectiveness of the academic advising system at Houston Baptist University, an "Advisor Perception Inventory" was used to add information to the computer data bank. The two summary reports generated are discussed. (MLW)

  4. Biogenic Emission Inventory System (BEIS)

    EPA Pesticide Factsheets

    Biogenic Emission Inventory System (BEIS) estimates volatile organic compound (VOC) emissions from vegetation and nitric oxide (NO) emission from soils. Recent BEIS development has been restricted to the SMOKE system

  5. Use of seagrass meadows as an adaptation measure to climate change for reducing port agitation

    NASA Astrophysics Data System (ADS)

    Sánchez-Arcilla, Agustín; Lin, Jue; Pau Sierra, Joan; Gracia, Vicenç; Casas-Prat, Merce; Virgili, Marc

    2014-05-01

    One of the best-known consequences of the greenhouse effect and the resulting global warming is sea-level rise. However, sea level rise is not the only process of concern to coastal communities. The greenhouse effect and the complex interactions in atmospheric processes is expected to produce changes in near-surface wind and pressure patterns, which in turn can affect the pattern of another important coastal driver: the wave field. Changes in wave conditions can affect the wave pattern within harbours as shown by Casas-Prat and Sierra (2012), increasing port agitation and, as a consequence, reducing the safety and comfort of the users, decreasing operation performance or even generating port inactivity. This effect will be enhanced by an increase in mean sea level. To avoid costly structural measure there are "green" options such as sea-grass that can attenuate wave energy (Koftis et al., 2013), since their roots induce sea bottom roughness and their stems and leaves increase the drag coefficient. The combined effect of vegetation is, thus, to create drag forces that dissipate part of the energy from incoming waves. Casas-Prat and Sierra (2013) showed that wave patterns may change in the future in certain areas of the Catalan Coast (northwestern Mediterranean) and as a consequence port agitation could be affected by changes in wave height or direction as well in those areas. The suggested "green" measures can help to prevent potential negative effects on port operations. The adaptive approach, depending on the downscaled climatic projections, would combine vegetation (as for example the existence of a sea-grass meadow in the vicinity of the harbour entrance) with some structural reinforcement if required. In this paper, the wave projections of Casas-Prat and Sierra (2013) are used together with a Boussinesq-type model to study wave propagation in several harbours of the Catalan Coast. This analysis of harbour oscillations is carried out for present conditions and

  6. Predictors of Nursing Home Admission among Alzheimer's Disease Patients with Psychosis and/or Agitation

    PubMed Central

    Miller, Edward Alan; Schneider, Lon S.; Rosenheck, Robert A.

    2014-01-01

    Background The purpose of this study is to identify factors that predict nursing home placement among community-dwelling Alzheimer's Disease (AD) patients with psychosis or agitation in a randomized clinical trial. Methods 418 participants with AD enrolled in the CATIE-AD trial of anti-psychotic medications and having no evidence of nursing home use at baseline were followed 9 months post-random assignment using data provided by caregiver proxy. χ2 tests, t-tests and Cox proportional hazard modeling were used to examine the baseline correlates of nursing home use. Results Of outpatients with no prior nursing home use, 15.0% were placed in a nursing home in the 9 months following baseline, with the average time to placement being 122 days. Bivariate analyses indicate that those with prior outpatient mental health use at study entry were more likely to be admitted; so too were those with worse physical functioning—lower scores on the AD Cooperative Study Activities of Daily Living Scale (ADCS-ADL), lower utility scores on the Health Utility Index (HUI)-III, and worse cognition on the Mini-Mental State Examination. Controlling for other factors, non-Hispanic white race (hazard ratio [HR]=2.16) and prior mental health use (HR=1.87) increased the likelihood of admission. Those with higher ADCS-ADL scores were less likely to be placed (HR=0.97). Conclusion Factors leading to nursing home entry among psychotic/agitated AD patients are similar to the general population, though high incidence of nursing home entry highlights the importance of accounting for such utilization in health economic studies of AD outcomes. It also highlights the importance of using information on ADLs and other characteristics to develop profiles identifying those at greater or lesser risk of nursing home entry and, in so doing inform population planning associated with AD and identification of those patients and caregivers who might benefit most from interventions to prevent eventual placement

  7. 27 CFR 40.523 - Inventories.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2011-04-01 2011-04-01 false Inventories. 40.523... Inventories. Every manufacturer of processed tobacco must provide a true and accurate inventory on TTB F 5210.9 in accordance with instructions for the form. The manufacturer must make such an inventory at...

  8. 27 CFR 19.353 - Storage inventories.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Storage inventories. 19..., DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Storage Inventories § 19.353 Storage inventories. Each warehouseman shall take a physical inventory of all spirits and wines held in the storage...

  9. 10 CFR 39.37 - Physical inventory.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Physical inventory. 39.37 Section 39.37 Energy NUCLEAR... inventory. Each licensee shall conduct a semi-annual physical inventory to account for all licensed material received and possessed under the license. The licensee shall retain records of the inventory for 3...

  10. 27 CFR 40.201 - Inventories.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Inventories. 40.201... PROCESSED TOBACCO Operations by Manufacturers of Tobacco Products Inventories and Reports § 40.201 Inventories. Every manufacturer of tobacco products shall make true and accurate inventories on Form...

  11. 27 CFR 20.170 - Physical inventory.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Physical inventory. 20.170... Users of Specially Denatured Spirits Inventory and Records § 20.170 Physical inventory. Once in each... physical inventory of each formula of new and recovered specially denatured spirits. (Approved by...

  12. 27 CFR 20.170 - Physical inventory.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Physical inventory. 20.170... Users of Specially Denatured Spirits Inventory and Records § 20.170 Physical inventory. Once in each... physical inventory of each formula of new and recovered specially denatured spirits. (Approved by...

  13. 27 CFR 40.201 - Inventories.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2011-04-01 2011-04-01 false Inventories. 40.201... PROCESSED TOBACCO Operations by Manufacturers of Tobacco Products Inventories and Reports § 40.201 Inventories. Every manufacturer of tobacco products shall make true and accurate inventories on Form...

  14. 10 CFR 39.37 - Physical inventory.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Physical inventory. 39.37 Section 39.37 Energy NUCLEAR... inventory. Each licensee shall conduct a semi-annual physical inventory to account for all licensed material received and possessed under the license. The licensee shall retain records of the inventory for 3...

  15. 27 CFR 19.981 - Inventories.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Inventories. 19.981... Spirits § 19.981 Inventories. Proprietors shall take actual physical inventory of all spirits (including... § 19.988. The results of the inventory shall be posted in the applicable records required by §...

  16. 27 CFR 40.523 - Inventories.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Inventories. 40.523... Inventories. Every manufacturer of processed tobacco must provide a true and accurate inventory on TTB F 5210.9 in accordance with instructions for the form. The manufacturer must make such an inventory at...

  17. Removal of copper powder from aqueous solution by cementation using an agitated vessel.

    PubMed

    Amin, N K; El-Ashtouky, E-S Z; Abdelwahab, O

    2014-01-01

    The present study is concerned with the removal of copper powder from aqueous solution by cementation on a stationary disc placed inside an agitated vessel. The influence of several parameters on the rate of cementation, such as initial copper sulphate concentration, impeller rotational speed, presence of surfactant (Triton X-100), distance between the disc and the impeller, type of blade turbine and presence of baffles, has been investigated. The rate of cementation was found to increase with increasing impeller rotational speed and initial copper sulphate concentration. On the other hand, the rate decreases with increasing distance between the disc and the impeller. The rate of cementation was inhibited in solutions containing Triton X-100. Performance of a four-blade 90 degree turbine with regard to the rate of copper cementation was superior to the performance of a four-blade 45 degree pitched turbine. The present data can be correlated in terms of mass transfer coefficient of cementation as Sh = 0.905 Sc0.33 Re0.89 (d/l)0.41 (four-blade 90 degree turbine); Sh = 0.815 Sc0.33Re0.79 (d/l)0.47 (four-blade 45 degree pitched turbine), for the conditions 2035 < Sc < 2810 and 35,000 < Re < 179,000.

  18. Critical review and meta-analysis of serial agitated dilutions in experimental toxicology.

    PubMed

    Linde, K; Jonas, W B; Melchart, D; Worku, F; Wagner, H; Eitel, F

    1994-07-01

    1. We conducted an overview and quantitative meta-analysis of all experimental literature on the protective effects of serial agitated dilutions (SADs) of toxin preparations. 2. Articles were systematically collected and evaluated for scientific quality using pre-defined methodological criteria and then independently analysed for validity. 3. We found 105 publications exploring the effects of SAD preparations in toxicological systems. 4. The quality of evidence in these studies was low with only 43% achieving one half of the maximum possible quality score and only 31% reported in a fashion that permitted reevaluation of the data. 5. Very few studies were independently replicated using comparable models. 6. Among the high quality studies, positive effects were reported 50% more often than negative effects. 7. Four of 5 outcomes meeting quality and comparability criteria for meta-analysis showed positive effects from SAD preparations. 8. Average percent protection over controls in these preparations was 19.7 (95%Cl 6.2-33.2). 9. Further research with special attention to methodological detail and independent replication should be done.

  19. Recovery of Copper from Effluents by Cementation on Aluminum in a Multirotating Cylinder-Agitated Vessel

    NASA Astrophysics Data System (ADS)

    Abdel-Aziz, M. H.; El-Ashtoukhy, E.-S. Z.; Bassyouni, M.

    2016-02-01

    Recovery of copper from synthetic waste solution using cementation technique in a new agitated vessel employing multirotating aluminum cylinders impeller was investigated. Parameters studied are cylinder diameter, rotation speed, initial copper ion concentrations, and effect of surfactants. Solution analysis and scanning electron microscopy were employed to investigate the kinetic and mechanism of the process. The rate of recovery was found to be at its maximum value at the operating conditions of 350 rpm rotation speed, 5000 ppm initial CuSO4 concentration, and 1.2 cm cylinder diameter. All data were correlated by the dimensionless equation: {Sh} = 1.16 {Sc}^{0.33} {Re}^{0.63} ( {{d_{{c}} }/L} )^{0.54}, with an average deviation of ±8.5 pct and a standard deviation of 5.88 pct. Presence of nonylphenol ethoxylate surfactant in the solution decreased the rate of recovery by an amount ranging from 2.94 to 38.57 pct depending on the operating conditions. The present geometry gave higher rates of recovery compared to both the single rotating cylinder and rotating disc reactor.

  20. Stabilization of bovine insulin against agitation-induced aggregation using RNA aptamers.

    PubMed

    Malik, Ravinder; Roy, Ipsita

    2013-08-16

    Stabilization of monomeric insulin is a primary requirement for preserving the efficacy of the final formulation. Degraded and/or aggregated protein as well as the presence of any of the conventional excipients can result in immunogenic or anaphylactic reactions, and reduced bioavailability of the protein drug. The aim of this work was to select novel RNA-based stabilizers of bovine insulin which would recognize and bind to the monomeric protein and help retain its bioactivity. RNA aptamers were selected by an in vitro selection method. They were screened for their ability to inhibit insulin fibrillation using agitation as a stress condition. The in vitro activity of insulin was determined by phosphorylation of downstream proteins in the cell. In vivo bioactivity was determined in a diabetic rat model. RNA aptamers, which bound to insulin with very low dissociation constants and high specificity, were selected. These sequences were aligned and consensus regions were found. The RNA sequences had no effect on the signalling cascade initiated by insulin. The bioactivity of insulin, as measured by its ability to lower plasma glucose level in a diabetic rat model, also remained unchanged. RNA aptamers are a novel class of protein stabilizers which have the ability to disrupt protein-protein interactions and hence inhibit protein aggregation. Their non-toxic and non-immunogenic nature makes such formulations safe for use.

  1. Successful child psychotherapy of attention deficit/hyperactive disorder: an agitated depression explanation.

    PubMed

    Seitler, Burton Norman

    2008-09-01

    Science tries to explain phenomena in ways that are demonstrable and replicable to develop logical, coherent, parsimonious, and predictive theoretical systems. Yet hyperactive children are given stimulants to "calm" them down, despite the fact that science would predict stimulants would increase hyperactivity. Bradley (1937, 1950) observed that half of the behavior-problem children to whom he administered a stimulant for one week became subdued. He called this finding paradoxical, speculating that inhibitory centers of the central nervous system were stimulated. While Bradley's assertion of a paradoxical reverse effect in children may be an empirical observation, it is not an explanation. The Attention Deficit/Hyperactive Disorder (ADHD) is inferred to exist from hyperactive behavior, which in turn, is inferred to be neurological in origin, a circular argument. An inevitable consequence of the belief in the hypothetical neurological etiology of ADHD is that children are typically given stimulants. Using the case of a seven-year old child, described as experiencing ADHD, who was treated successfully without medication as an illustration, the author provides an alternative, more parsimonious explanation of the etiology, suggesting that ADHD is related to agitated depression.

  2. Drying process optimization for an API solvate using heat transfer model of an agitated filter dryer.

    PubMed

    Nere, Nandkishor K; Allen, Kimberley C; Marek, James C; Bordawekar, Shailendra V

    2012-10-01

    Drying an early stage active pharmaceutical ingredient candidate required excessively long cycle times in a pilot plant agitated filter dryer. The key to faster drying is to ensure sufficient heat transfer and minimize mass transfer limitations. Designing the right mixing protocol is of utmost importance to achieve efficient heat transfer. To this order, a composite model was developed for the removal of bound solvent that incorporates models for heat transfer and desolvation kinetics. The proposed heat transfer model differs from previously reported models in two respects: it accounts for the effects of a gas gap between the vessel wall and solids on the overall heat transfer coefficient, and headspace pressure on the mean free path length of the inert gas and thereby on the heat transfer between the vessel wall and the first layer of solids. A computational methodology was developed incorporating the effects of mixing and headspace pressure to simulate the drying profile using a modified model framework within the Dynochem software. A dryer operational protocol was designed based on the desolvation kinetics, thermal stability studies of wet and dry cake, and the understanding gained through model simulations, resulting in a multifold reduction in drying time.

  3. Studies on heat transfer to Newtonian and non-Newtonian fluids in agitated vessel

    NASA Astrophysics Data System (ADS)

    Triveni, B.; Vishwanadham, B.; Venkateshwar, S.

    2008-09-01

    Heat transfer studies to Newtonian and non-Newtonian fluids are carried out in a stirred vessel fitted with anchor/turbine impeller and a coil for heating/cooling with an objective of determining experimentally the heat transfer coefficient of few industrially important systems namely castor oil and its methyl esters, soap solution, CMC and chalk slurries. The effect of impeller geometry, speed and aeration is investigated. Generalized Reynolds and Prandtl numbers are calculated using an apparent viscosity for non-Newtonian fluids. The data is correlated using a Sieder-Tate type equation. A trend of increase in heat transfer coefficient with RPM in presence and absence of solids has been observed. Relatively high values of Nusselt numbers are obtained for non-Newtonian fluids when aeration is coupled with agitation. The contribution of natural convection to heat transfer has been accounted for by incorporating the Grashof number. The correlations developed based on these studies are applied for design of commercial scale soponification reactor. Power per unit volume resulted in reliable design of a reactor.

  4. Phosphorus recovery from urine with different magnesium resources in an air-agitated reactor.

    PubMed

    Liu, Xiaoning; Hu, Zhengyi; Mu, Jing; Zang, Haixing; Liu, Li

    2014-01-01

    Phosphorus (P) recovery through struvite formation from urine has gained increasing attention as an approach to alleviate the potential shortage of P. The concentration of magnesium (Mg) is lower than those of ammonium and ortho-phosphate in urine, so the cost of adding Mg is a major economic constraint for P recovery. This study aims at evaluating the potential of seawater and bittern as Mg resources to recover P from urine in an air-agitated reactor. Results indicate that effects of seawater and bittern on P recovery from urine are comparable to that of magnesium chloride, with an average crystal size of around 34 μm under an Mg/P molar ratio of 1.3. The average crystal size of the struvite crystals obtained from high P concentration urine with different Mg resources showed no significant difference, whereas larger crystal size was obtained from low P concentration urine with bittern as Mg resource. Analysis of mainly rod-like crystals produced in the reactor indicates the presence of pure struvite (>98.0% by weight) with small amounts of calcium (<1.39% by weight). Bittern is recommended as a suitable Mg resource for P recovery because of its high Mg content and the convenience it offers in terms of transportation and storage.

  5. Mechanical agitation induces counterintuitive aggregation of pre-dispersed carbon nanotubes.

    PubMed

    Fernandes, Ricardo M F; Buzaglo, Matat; Regev, Oren; Furó, István; Marques, Eduardo F

    2017-05-01

    Mechanical agitation is commonly used to fragment and disperse insoluble materials in liquids. However, here we show that when pristine single-walled carbon nanotubes pre-dispersed in water are subject to vortex-shaking for very short periods (typically 10-60s, power density ∼0.002WmL(-1)), re-aggregation counterintuitively occurs. The initial dispersions are produced using surfactants as dispersants and powerful tip sonication (∼1WmL(-1)) followed by centrifugation. Detailed imaging by light and electron microscopies shows that the vortex-induced aggregates consist of loose networks (1-10(2)μm in size) of intertwined tubes and thin bundles. The average aggregate size increases with vortexing time in an apparently logarithmic manner and depends on the dispersant used, initial concentration of nanotubes and size distribution of bundles. The aggregation is, nonetheless, reversible: if the vortex-shaken dispersions are mildly bath-sonicated (∼0.03WmL(-1)), the flocs break down and re-dispersal occurs. Molecular insight for the mechanism behind this surprising phenomenon is put forth.

  6. Peru Mercury Inventory 2006

    USGS Publications Warehouse

    Brooks, William E.; Sandoval, Esteban; Yepez, Miguel A.; Howard, Howell

    2007-01-01

    In 2004, a specific need for data on mercury use in South America was indicated by the United Nations Environmental Programme-Chemicals (UNEP-Chemicals) at a workshop on regional mercury pollution that took place in Buenos Aires, Argentina. Mercury has long been mined and used in South America for artisanal gold mining and imported for chlor-alkali production, dental amalgam, and other uses. The U.S. Geological Survey (USGS) provides information on domestic and international mercury production, trade, prices, sources, and recycling in its annual Minerals Yearbook mercury chapter. Therefore, in response to UNEP-Chemicals, the USGS, in collaboration with the Economic Section of the U.S. Embassy, Lima, has herein compiled data on Peru's exports, imports, and byproduct production of mercury. Peru was selected for this inventory because it has a 2000-year history of mercury production and use, and continues today as an important source of mercury for the global market, as a byproduct from its gold mines. Peru is a regional distributor of imported mercury and user of mercury for artisanal gold mining and chlor-alkali production. Peruvian customs data showed that 22 metric tons (t) of byproduct mercury was exported to the United States in 2006. Transshipped mercury was exported to Brazil (1 t), Colombia (1 t), and Guyana (1 t). Mercury was imported from the United States (54 t), Spain (19 t), and Kyrgyzstan (8 t) in 2006 and was used for artisanal gold mining, chlor-alkali production, dental amalgam, or transshipment to other countries in the region. Site visits and interviews provided information on the use and disposition of mercury for artisanal gold mining and other uses. Peru also imports mercury-containing batteries, electronics and computers, fluorescent lamps, and thermometers. In 2006, Peru imported approximately 1,900 t of a wide variety of fluorescent lamps; however, the mercury contained in these lamps, a minimum of approximately 76 kilograms (kg), and in

  7. Cradle-to-gate life cycle inventory of vancomycin hydrochloride.

    PubMed

    Ponder, Celia; Overcash, Michael

    2010-02-15

    A life cycle analysis on the cradle-to-gate production of vancomycin hydrochloride, which begins at natural resource extraction and spans through factory (gate) production, not only shows all inputs, outputs, and energy usage to manufacture the product and all related supply chain chemicals, but can highlight where process changes would have the greatest impact on raw material and energy consumption and emissions. Vancomycin hydrochloride is produced by a low-yield fermentation process that accounts for 47% of the total cradle-to-gate energy. The fermentation step consumes the most raw materials and energy cradle-to-gate. Over 75% of the total cradle-to-gate energy consumption is due to steam use; sterilization within fermentation is the largest user of steam. Aeration and agitation in the fermentation vessels use 65% of the cradle-to-gate electrical energy. To reduce raw materials, energy consumption, and the associated environmental footprint of producing vancomycin hydrochloride, other sterilization methods, fermentation media, nutrient sources, or synthetic manufacture should be investigated. The reported vancomycin hydrochloride life cycle inventory is a part of a larger life cycle study of the environmental consequences of the introduction of biocide-coated medical textiles for the prevention of MRSA (methicillin-resistant Staphylococcus aureus) nosocomial infections.

  8. Serum high-sensitivity C-reactive protein: A delicate sentinel elevated in drug-free acutely agitated patients with schizophrenia.

    PubMed

    Pan, Shujuan; Tan, Yunlong; Yao, Shangwu; Zhao, Xiaoyan; Xiong, Jing

    2016-12-30

    Increased levels of high-sensitivity C reactive protein (hsCRP) have been reported in schizophrenia, but to date, no study is designed to examine serum hsCRP in acutely agitated patients with schizophrenia, an extreme state that requires immediate diagnosis and medical treatment. Serum hsCRP levels were assessed in 32 clinically acutely agitated patients and 42 healthy control subjects matched for demographic properties. Further, serum hsCRP levels in acutely agitated patients were compared with control subjects and with the levels after the patients were treated with anti-psychiatric medications. Meanwhile, the influence of clinical subtypes, family history, and gender, as well as the levels of white blood cell (WBC) counts were also considered. In results, serum hsCRP levels were significantly higher in acutely agitated patients with schizophrenia than in healthy subjects. The elevation of serum hsCRP in patients was not affected by gender, family history (P>0.05), and clinical classification of schizophrenia (P>0.05). However, the elevation of hsCRP was suppressed by the medical treatment for schizophrenia with acute agitation (P<0.05). In addition, WBC counts, another inflammation-related indicator, were also increased significantly in acutely agitated patients compared with healthy subjects, consistent with the elevation of serum hsCRP. In conclusion, hsCRP is an important indicator of immune alterations in the pathogenesis of schizophrenia and has potential to be developed into a sensitive marker for the acute agitation in schizophrenia.

  9. Agitation Rate and Time for Complete Dissolution in BCS Biowaivers Based on Investigation of a BCS Biowaiver for Dexketoprofen Tablets.

    PubMed

    Garcia-Arieta, Alfredo; Gordon, John; Gwaza, Luther; Mangas-Sanjuan, V; Álvarez, Covadonga; Torrado, Juan J

    2015-09-08

    The objective of the present work is to investigate the validity of the existing requirements for BCS biowaivers of immediate release products containing a class I drug in relation to the agitation rate (50 or 75 rpm in the paddle apparatus) and the time limit for complete dissolution (30 min) in the current biowaivers in vitro dissolution tests. Further, the possibility of extensions will be examined since it has been proposed that the time limit for complete dissolution should be revised to 60 min, and also, if cone formation occurs with apparatus 2 at 50 rpm, then a higher agitation rate is acceptable to eliminate it. The development of four generic dexketoprofen immediate release tablets is described. Dexketoprofen is the eutomer of ketoprofen. According to the BCS, dexketoprofen is a class I drug. Three out of the four products failed to show bioequivalence for Cmax in the initial bioequivalence study conducted with the product despite similar but nonrapid dissolution profiles at 50 rpm in the paddle apparatus, or similar and very rapid dissolution profiles at 75 rpm. In conclusion, these data indicate that BCS biowaivers for class I drugs should be granted only when dissolution with the paddle apparatus is complete in 30 min at 50 rpm. The time limit for complete dissolution should not be extended to 60 min. Furthermore, the agitation rate should not be increased to 75 rpm, even in the case of a coning effect.

  10. The Closing Group: Therapeutic recreation for nursing home residents with dementia and accompanying agitation and/or anxiety.

    PubMed

    Putman, Laraine; Wang, Jen-Ting

    2007-01-01

    Long-term care residents who have a dementia diagnosis could account for as much 50% of a nursing home's population. Often residents with dementia experience a distressing behavioral symptom that affects the resident experiencing the symptom(s), other nursing home residents, visitors, and staff. The Closing Group intervention was developed as a nonpharmacological alternative that aims to reduce agitation and anxiety, increase socialization, decrease restraint use, and decrease antipsychotic drug use for selected residents with a dementia diagnosis. The program was based on an understanding of the contributing factors to agitation and anxiety, the nursing home environment as it relates to behavior, and the offering of resident-driven recreational activities. The purpose of this 2-year study was, with use of multiple measures, to examine the extent to which the Closing Group intervention has met its goals. A sample of 16 long-term care residents was offered attendance at the group. Findings in the area of reducing agitation and anxiety were encouraging to the extent that further study with larger samples is needed.

  11. Do Bartonella Infections Cause Agitation, Panic Disorder, and Treatment-Resistant Depression?

    PubMed Central

    Schaller, James L.; Burkland, Glenn A.; Langhoff, P.J.

    2007-01-01

    Introduction Bartonella is an emerging infection found in cities, suburbs, and rural locations. Routine national labs offer testing for only 2 species, but at least 9 have been discovered as human infections within the last 15 years. Some authors discuss Bartonella cases having atypical presentations, with serious morbidity considered uncharacteristic of more routine Bartonella infections. Some atypical findings include distortion of vision, abdominal pain, severe liver and spleen tissue abnormalities, thrombocytopenic purpura, bone infection, arthritis, abscesses, heart tissue and heart valve problems. While some articles discuss Bartonella as a cause of neurologic illnesses, psychiatric illnesses have received limited attention. Case reports usually do not focus on psychiatric symptoms and typically only as incidental comorbid findings. In this article, we discuss patients exhibiting new-onset agitation, panic attacks, and treatment-resistant depression, all of which may be attributed to Bartonella. Methods Three patients receiving care in an outpatient clinical setting developed acute onset personality changes and agitation, depression, and panic attacks. They were retrospectively examined for evidence of Bartonella infections. The medical and psychiatric treatment progress of each patient was tracked until both were significantly resolved and the Bartonella was cured. Results The patients generally seemed to require higher dosing of antidepressants, benzodiazepines, or antipsychotics in order to function normally. Doses were reduced following antibiotic treatment and as the presumed signs of Bartonella infection remitted. All patients improved significantly following treatment and returned to their previously healthy or near-normal baseline mental health status. Discussion New Bartonella species are emerging as human infections. Most do not have antibody or polymerase chain reaction (PCR) diagnostic testing at this time. Manual differential examinations are of

  12. Hypnotic Depth and the Incidence of Emergence Agitation and Negative Postoperative Behavioral Changes

    PubMed Central

    Faulk, Debra J.; Twite, Mark D.; Zuk, Jeannie; Pan, Zhaoxing; Wallen, Brett; Friesen, Robert H.

    2011-01-01

    Background Emergence agitation (EA) and negative postoperative behavioral changes (NPOBC) are common in children, though the etiology remains unclear. We investigated whether longer times under deep hypnosis as measured by Bispectral Index™ (BIS) monitoring would positively correlate with a greater incidence of EA in the post anesthesia care unit (PACU) and a greater occurrence of NPOBC in children after discharge. Methods We enrolled 400 children, ages 1–12 years old, scheduled for dental procedures under general anesthesia. All children were induced with high concentration sevoflurane and BIS monitoring was continuous from induction through recovery in the PACU. A BIS reading <45 was considered deep hypnosis. The presence of EA was assessed in the PACU using the Pediatric Anesthesia Emergence Delirium Scale (PAED). NPOBC were assessed using the Post-Hospital Behavior Questionnaire (PHBQ), completed by parents 3–5 days post-operatively. Data were analyzed using logistic regression, with a p<0.05 considered statistically significant. Results The incidence of EA was 27% (99/369) and the incidence of NPOBC was 8.8% (28/318). No significant differences in the incidence of EA or NPOBC were seen with respect to length of time under deep hypnosis as measured by a BIS value of less than 45. Conclusion Our data revealed no significant correlation between the length of time under deep hypnosis (BIS<45) and the incidence of EA or NPOBC. Within this population, these behavioral disturbances do not appear to be related to the length of time under a deep hypnotic state as measured by the BIS. PMID:19968807

  13. Flow-induced agitations create a granular fluid: effective viscosity and fluctuations.

    PubMed

    Nichol, Kiri; van Hecke, Martin

    2012-06-01

    We fluidize a granular medium with localized stirring in a split-bottom shear cell. We probe the mechanical response of quiescent regions far from the main flow by observing the vertical motion of cylindrical probes rising, sinking, and floating in the grains. First, we find that the probe motion suggests that the granular material behaves in a liquid-like manner: high-density probes sink and low-density probes float at the depth given by Archimedes' law. Second, we observe that the drag force on moving probes scales linearly with their velocity, which allows us to define an effective viscosity for the system. This effective viscosity is inversely proportional to the rotation rate of the disk which drives the split bottom flow. Moreover, the apparent viscosity depends on radius and mass of the probe: despite the linear dependence of the drag forces on sinking speed of the probe, the granular medium is not simply Newtonian, but exhibits a more complex rheology. The decrease of viscosity with filling height of the cell, combined with the poor correlation between local strain rate and viscosity, suggests that the fluid-like character of the material is set by agitations generated in the stirred region: the relation between applied stress and observed strain rate in one location depends on the strain rate in another location. We probe the nature of the granular fluctuations that we believe mediates these nonlocal interactions by characterizing the small and random up and down motion that the probe experiences. These Gaussian fluctuations exhibit a mix of diffusive and subdiffusive behavior at short times and saturate at a value of roughly 1/10th of a grain diameter longer times, consistent with the picture of a random walker in a potential well. The product of crossover time and effective viscosity is constant, evidencing a direct link between fluctuations and viscosity.

  14. The effect of impeller type on silica sol formation in laboratory scale agitated tank

    NASA Astrophysics Data System (ADS)

    Nurtono, Tantular; Suprana, Yayang Ade; Latif, Abdul; Dewa, Restu Mulya; Machmudah, Siti; Widiyastuti, Winardi, Sugeng

    2016-02-01

    The multiphase polymerization reaction of the silica sol formation produced from silicic acid and potassium hydroxide solutions in laboratory scale agitated tank was studied. The reactor is equipped with four segmental baffle and top entering impeller. The inside diameter of reactor is 9 cm, the baffle width is 0.9 cm, and the impeller position is 3 cm from tank bottom. The diameter of standard six blades Rushton and three blades marine propeller impellers are 5 cm. The silicic acid solution was made from 0.2 volume fraction of water glass (sodium silicate) solution in which the sodium ion was exchanged by hydrogen ion from cation resin. The reactor initially filled with 286 ml silicic acid solution was operated in semi batch mode and the temperature was kept constant in 60 °C. The 3 ml/minute of 1 M potassium hydroxide solution was added into stirred tank and the solution was stirred. The impeller rotational speed was varied from 100 until 700 rpm. This titration was stopped if the solution in stirred tank had reached the pH of 10-The morphology of the silica particles in the silica sol product was analyzed by Scanning Electron Microscope (SEM). The size of silica particles in silica sol was measured based on the SEM image. The silica particle obtained in this research was amorphous particle and the shape was roughly cylinder. The flow field generated by different impeller gave significant effect on particle size and shape. The smallest geometric mean of length and diameter of particle (4.92 µm and 2.42 µm, respectively) was generated in reactor with marine propeller at 600 rpm. The reactor with Rushton impeller produced particle which the geometric mean of length and diameter of particle was 4.85 µm and 2.36 µm, respectively, at 150 rpm.

  15. Effect of ketamine combined with butorphanol on emergence agitation of postoperative patients with gastric cancer

    PubMed Central

    Lin, Liang; Liu, Shuncui; Chen, Zhenyi; Lin, Shaoli

    2016-01-01

    Background This study aimed to investigate the effect of ketamine combined with butorphanol on emergence agitation (EA) in postoperative gastric cancer patients. Materials and methods A total of 150 patients with gastric cancer were included and divided into group B (1 mg butorphanol before anesthesia induction, n=50), group K (1 mg/kg ketamine, n=50), and group C (1 mg butorphanol combined with 1 mg/kg ketamine, n=50). Mean arterial pressure (MAP) and heart rate (HR) at the end of operation, just before extubation (T0) and at 0 minute (T1), 5 minutes (T2), and 30 minutes (T3) after extubation were compared. Statistical analysis of recovery time, extubation time, time in postanesthesia care unit, and EA incidence and adverse reactions were performed. Results There were no differences among groups with respect to MAP and HR at T0 and T1 (P>0.05). Compared with patients in group C, significant reduction of MAP and HR were observed in groups K and B at T2 and T3 (P<0.05), while no differences were found between group K and group B (P>0.05). Recovery time, extubation time, time in postanesthesia care unit, and incidence of EA in group C were significantly less than those in groups K and B (P<0.05), but no differences were observed between group K and group B (P>0.05). Total incidence of adverse reactions were significantly increased in group K compared to those in groups C and B (P<0.05). Conclusion Injection of ketamine combined with butorphanol before anesthesia induction was more effective than injection of ketamine or butorphanol separately in the prevention of EA. PMID:27217761

  16. Effects of physical agitation on yield of greenhouse-grown soybean

    NASA Technical Reports Server (NTRS)

    Jones, R. S.; Mitchell, C. A.

    1992-01-01

    Agronomic and horticultural crop species experience reductions in growth and harvestable yield after exposure to physical agitation (also known as mechanical stress), as by wind or rain. A greenhouse study was conducted to test the influence of mechanical stress on soybean yield and to determine if exposure to mechanical stress during discrete growth periods has differential effects on seed yield. A modified rotatory shaker was used to apply seismic (i.e., shaking) stress. Brief, periodic episodes of seismic stress reduced stem length, total seed dry weight, and seed number of soybean [Glycine max (L.) Merr.]. Lodging resistance was greater for plants stressed during vegetative growth or throughout vegetative and reproductive growth than during reproductive growth only. Seed dry weight yield was reduced regardless of the timing or duration of stress application, but was lowest when applied during reproductive development. Seismic stress applied during reproductive growth stages R1 to R2 (Days 3 to 4) was as detrimental to seed dry weight accumulation as was stress applied during growth stages R1 to R6 (Days 39 to 42). Seed dry weight per plant was highly correlated with seed number per plant, and seed number was correlated with the seed number of two- and three-seeded pods. Dry weight per 100 seeds was unaffected by seismic-stress treatment. Growth and yield reductions resulting from treatments applied only during the vegetative stage imply that long-term mechanical effects were induced, from which the plants did not fully recover. It is unclear which yield-controlling physiological processes were affected by mechanical stress. Both transient and long-term effects on yield-controlling processes remain to be elucidated.

  17. Barbiturate Induction for the Prevention of Emergence Agitation after Pediatric Sevoflurane Anesthesia

    PubMed Central

    Nakahara, Haruna; Kimoto, Ayako; Beppu, Yuki; Yoshimura, Maki; Kojima, Toshiyuki; Fukano, Taku

    2015-01-01

    OBJECTIVES: Emergence agitation (EA) is a common and troublesome problem in pediatric patients recovering from general anesthesia. The incidence of EA is reportedly higher after general anesthesia maintained with sevoflurane, a popular inhalational anesthetic agent for pediatric patients. We conducted this prospective, randomized, double-blind study to test the effect of an intravenous ultra-short–acting barbiturate, thiamylal, administered during induction of general anesthesia on the incidence and severity of EA in pediatric patients recovering from Sevoflurane anesthesia. METHODS: Fifty-four pediatric patients (1 to 6 years of age) undergoing subumbilical surgeries were randomized into 2 groups. Patients received either intravenous thiamylal 5mg/kg (Group T) or inhalational Sevoflurane 5% (Group S) as an anesthetic induction agent. Following induction, general anesthesia was maintained with Sevoflurane and nitrous oxide (N2O) in both groups. To control the intra- and post-operative pain, caudal block or ilioinguinal/iliohypogastric block was performed. The incidence and severity of EA were evaluated by using the Modified Objective Pain Scale (MOPS: 0 to 6) at 15 and 30 min after arrival in the post-anesthesia care unit (PACU). RESULTS: Fifteen minutes after arrival in the PACU, the incidence of EA in Group T (28%) was significantly lower than in Group S (64%; p = 0.023) and the MOPS in Group T (median 0, range 0 to 6) was significantly lower than in Group S (median 4, range 0 to 6; p = 0.005). The interval from discontinuation of Sevoflurane to emergence from anesthesia was not significantly different between the 2 groups. CONCLUSIONS: Thiamylal induction reduced the incidence and severity of EA in pediatric patients immediately after Sevoflurane anesthesia. PMID:26472953

  18. Pacific Northwest Resources Inventory Demonstration

    NASA Technical Reports Server (NTRS)

    Nichols, J. D.

    1976-01-01

    The Pacific Northwest Land Resource Inventory Demonstration project is designed to demonstrate to users from state and local agencies in Washington, Oregon, and Idaho the cost effective role that Landsat derived information can play in natural resource planning and management when properly supported by ground and aircraft data. The project has been organized into five main phases: (1) maps and overlays, (2) early digital image analysis, (3) demonstration of applications using interactive image analysis, (4) Landsat products and land resources information systems, and (5) documentation. The demonstration project has been applied to Washington forestry, water inventory in southern Idaho, and monitoring of tansy ragwort in western Oregon.

  19. Global National Qualifications Framework Inventory

    ERIC Educational Resources Information Center

    Bjornavold, Jens; Pevec-Grm, Slava; Graham, Michael; Deij, Arjen; Singh, Madhu; Charkoun, Borhène; Agrawal, Shivani

    2013-01-01

    This publication is a global, country-by-country, inventory of National Qualifications Frameworks (NQFs). It is a copublication, prepared by two EU agencies, the European Training Foundation (ETF) and the Centre for the Development of Vocational Training (Cedefop); and UNESCO's Institute for Lifelong Learning (UIL) and the Section for TVET at…

  20. RFID Technology for Inventory Management

    SciTech Connect

    2012-05-01

    The Pacific Northwest National Laboratory is leveraging the use and application of radio frequency identification (RFID) technology to a variety of markets. Tagging and tracking of individual items for inventory control is revealing rich rewards through increased time efficiency and reduced human intervention.

  1. Narratives Validate Communicative Development Inventories.

    ERIC Educational Resources Information Center

    Eriksson, Marten

    2001-01-01

    Explores the criterion-related validity of the Swedish version of the Communicative Development Inventories--Words & Sentences (SECDI-W&S). In two follow-up procedures, SECDI-W&S was used to assess vocabulary and grammar skills in 32 children. Overall results confirm that the criterion-related validity of the SECDI is sound. (Author/VWL)

  2. Developing an Action Concept Inventory

    ERIC Educational Resources Information Center

    McGinness, Lachlan P.; Savage, C. M.

    2016-01-01

    We report on progress towards the development of an Action Concept Inventory (ACI), a test that measures student understanding of action principles in introductory mechanics and optics. The ACI also covers key concepts of many-paths quantum mechanics, from which classical action physics arises. We used a multistage iterative development cycle for…

  3. Sourcing Life Cycle Inventory Data

    EPA Science Inventory

    The collection and validation of quality lifecycle inventory (LCI) data can be the most difficult and time-consuming aspect of developing a life cycle assessment (LCA). Large amounts of process and production data are needed to complete the LCI. For many studies, the LCA analyst ...

  4. Children's Perception of Support Inventory.

    ERIC Educational Resources Information Center

    Rosen, Robert H.

    The Children's Perception of Support Inventory (CPSI) which assesses the extent to which children perceive their families and peer networks as understanding, responsive, and supportive is described. This measure was constructed (1) to differentiate children on family and peer-support scales and to demonstrate the relationship between the…

  5. RFID Technology for Inventory Management

    ScienceCinema

    None

    2016-07-12

    The Pacific Northwest National Laboratory is leveraging the use and application of radio frequency identification (RFID) technology to a variety of markets. Tagging and tracking of individual items for inventory control is revealing rich rewards through increased time efficiency and reduced human intervention.

  6. Influence of apheresis container size on the maintenance of platelet in vitro storage properties after a 30-h interruption of agitation.

    PubMed

    Wagner, Stephen J; Skripchenko, Andrey; Seetharaman, Shalini; Myrup, Andrew; Kurtz, James; Thomas-Montgomery, Dedeene; Awatefe, Helen; Moroff, Gary

    2010-08-01

    We have previously conducted studies investigating maintenance of apheresis platelet in vitro quality measures during storage under simulated shipping conditions in which agitation was interrupted. This study examines the effect of increasing bag surface area on the preservation of in vitro platelet properties during storage with continuous agitation and with a 30 h interruption of agitation. Apheresis platelets were collected in 100% plasma with the Amicus separator to provide two identical platelet products, each with approximately 4-5 x 10(11) platelets. After collection, the volume was divided equally between 1.0 and 1.3 L PL2410 containers. In an initial study, both products were continuously agitated. In a second study, both products were subjected to a single 30-h period of interrupted agitation between Days 2 and 3 of storage by placement in a standard shipping box at room temperature. In each study, units were assayed during storage for standard in vitro platelet quality measures. Platelets stored in the 1.3 L container maintained slightly greater mean pH during 7 day storage with either continuous agitation (n=6) or with a 30-h interruption of agitation (n=12) than those of similarly treated identical platelets stored in the 1.0 L container. Most noteworthy, in experiments with products stored in the 1.0 L container in which there was a large decrease in pH to levels <6.7 or <6.3 on days 5 or 7, respectively, the pH in the matched product stored in the 1.3 L container was substantially greater (0.17+/-06 and 0.37+/-0.09 pH units greater, n=4, respectively). Other measures showed either small differences or comparability of platelet in vitro parameters with storage in the two containers after an interruption of agitation.

  7. 1064-nm Nd:YAG and 980-nm Diode Laser EDTA Agitation on the Retention of an Epoxy-Based Sealer to Root Dentin.

    PubMed

    Macedo, Helena Suleiman de; Messias, Danielle Cristine Furtado; Rached-Júnior, Fuad Jacob; Oliveira, Ligia Teixeira de; Silva-Sousa, Yara Teresinha Correa; Raucci-Neto, Walter

    2016-01-01

    Root canal irrigants are used to minimize the negative effects of smear layer on endodontic sealer retention. The aim of this study was to evaluate the efficacy of agitation of 17% ethylenediaminetetraacetic acid (EDTA) with ultrasonic, 1064-nm Nd:YAG and 980-nm diode laser on the retention of an epoxy-based sealer to the root canal walls. Forty single-rooted bovine teeth were instrumented with ProTaper rotary system and divided into four groups according to the final irrigation protocol (n = 10): (1) 17% EDTA (control); (2) 17% EDTA with 50-s ultrasonic agitation; (3) 17% EDTA with 50-s diode laser (2-W) agitation; and (4) 17% EDTA with 50-s Nd:YAG (1.5-W) laser agitation. After endodontic filling with gutta-percha F5 master cone and Sealer 26, the roots were sectioned at the cervical, middle, and apical root thirds to obtain 1.5-mm slices. Push-out tests were performed using a universal testing machine at a 1 mm/min crosshead speed. Data were analyzed using two-way ANOVA and Tukey's tests (α=0.05). Apical root thirds had significant higher retention values than cervical and middle thirds (p < 0.05). EDTA with 1064-nm Nd:YAG or 980-nm diode laser presented the highest retention values and was significantly different from EDTA with ultrasonic agitation and EDTA only (p < 0.05). Adhesive failures were predominant to EDTA only group. Mixed failures were predominant to all agitation groups. 1064-nm Nd:YAG and 980-nm diode laser EDTA agitation enhanced the retention of the epoxy-based sealer to the root canal walls compared with that due to EDTA only or EDTA with ultrasonic agitation.

  8. Cooperative forestry inventory project for Nevada

    NASA Technical Reports Server (NTRS)

    Thornhill, R.

    1981-01-01

    A forest inventory project employing computerized classification of LANDSAT data to inventory vegetation types in western Nevada is described. The methodology and applicability of the resulting survey are summarized.

  9. Inventory and Billing Systems for Multiple Users.

    ERIC Educational Resources Information Center

    Frazier, Lavon

    1985-01-01

    Washington State University developed a comprehensive supplies inventory system and a generalized billing system with multiple users in mind. The inventory management system and the service center billing system are described. (Author/MLW)

  10. Color Coding Organic Chemicals for Inventory Control.

    ERIC Educational Resources Information Center

    Wystrach, V. P.; George, Babu

    1985-01-01

    Describes a system in which organic chemicals are recoded for inventory control and reshelving purposes. The system works well in undergraduate organic chemistry or biology laboratories but can be expanded to handle a larger and more complicated inventory. (JN)

  11. 40 CFR 52.1533 - Emission inventories.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...). Subsequent revisions to the State's 1990 inventories were made, the last of which occurred on August 29, 1996... which are volatile organic compounds, nitrogen oxides, and carbon monoxide. The inventory covers...

  12. 40 CFR 52.1533 - Emission inventories.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...). Subsequent revisions to the State's 1990 inventories were made, the last of which occurred on August 29, 1996... which are volatile organic compounds, nitrogen oxides, and carbon monoxide. The inventory covers...

  13. Optimization of aeration and agitation rate for lipid and gamma linolenic acid production by Cunninghamella bainieri 2A1 in submerged fermentation using response surface methodology.

    PubMed

    Saad, Normah; Abdeshahian, Peyman; Kalil, Mohd Sahaid; Yusoff, Wan Mohtar Wan; Hamid, Aidil Abdul

    2014-01-01

    The locally isolated filamentous fungus Cunninghamella bainieri 2A1 was cultivated in a 5 L bioreactor to produce lipid and gamma-linolenic acid (GLA). The optimization was carried out using response surface methodology based on a central composite design. A statistical model, second-order polynomial model, was adjusted to the experimental data to evaluate the effect of key operating variables, including aeration rate and agitation speed on lipid production. Process analysis showed that linear and quadratic effect of agitation intensity significantly influenced lipid production process (P < 0.01). The quadratic model also indicated that the interaction between aeration rate and agitation speed had a highly significant effect on lipid production (P < 0.01). Experimental results showed that a lipid content of 38.71% was produced in optimum conditions using an airflow rate and agitation speed of 0.32 vvm and 599 rpm, respectively. Similar results revealed that 0.058(g/g) gamma-linolenic acid was produced in optimum conditions where 1.0 vvm aeration rate and 441.45 rpm agitation rate were used. The regression model confirmed that aeration and agitation were of prime importance for optimum production of lipid in the bioreactor.

  14. The effect of impeller type on silica sol formation in laboratory scale agitated tank

    SciTech Connect

    Nurtono, Tantular; Suprana, Yayang Ade; Latif, Abdul; Dewa, Restu Mulya; Machmudah, Siti; Widiyastuti, Winardi, Sugeng

    2016-02-08

    The multiphase polymerization reaction of the silica sol formation produced from silicic acid and potassium hydroxide solutions in laboratory scale agitated tank was studied. The reactor is equipped with four segmental baffle and top entering impeller. The inside diameter of reactor is 9 cm, the baffle width is 0.9 cm, and the impeller position is 3 cm from tank bottom. The diameter of standard six blades Rushton and three blades marine propeller impellers are 5 cm. The silicic acid solution was made from 0.2 volume fraction of water glass (sodium silicate) solution in which the sodium ion was exchanged by hydrogen ion from cation resin. The reactor initially filled with 286 ml silicic acid solution was operated in semi batch mode and the temperature was kept constant in 60 °C. The 3 ml/minute of 1 M potassium hydroxide solution was added into stirred tank and the solution was stirred. The impeller rotational speed was varied from 100 until 700 rpm. This titration was stopped if the solution in stirred tank had reached the pH of 10-The morphology of the silica particles in the silica sol product was analyzed by Scanning Electron Microscope (SEM). The size of silica particles in silica sol was measured based on the SEM image. The silica particle obtained in this research was amorphous particle and the shape was roughly cylinder. The flow field generated by different impeller gave significant effect on particle size and shape. The smallest geometric mean of length and diameter of particle (4.92 µm and 2.42 µm, respectively) was generated in reactor with marine propeller at 600 rpm. The reactor with Rushton impeller produced particle which the geometric mean of length and diameter of particle was 4.85 µm and 2.36 µm, respectively, at 150 rpm.

  15. Effect of aripiprazole lauroxil on agitation and hostility in patients with schizophrenia.

    PubMed

    Citrome, Leslie; Du, Yangchun; Risinger, Robert; Stankovic, Srdjan; Claxton, Amy; Zummo, Jacqueline; Bose, Anjana; Silverman, Bernard L; Ehrich, Elliot W

    2016-03-01

    This study aimed to evaluate the effects of aripiprazole lauroxil on hostility and aggressive behavior in patients with schizophrenia. Patients aged 18-70 years with a diagnosis of schizophrenia and currently experiencing an acute exacerbation or relapse were randomized to intramuscular (IM) aripiprazole lauroxil 441 mg (n=207), 882 mg (n=208), or placebo (n=207) for 12 weeks. In post-hoc analyses, hostility and aggression were assessed by the Positive and Negative Syndrome Scale (PANSS) Hostility item (P7) and a specific antihostility effect was assessed by adjusting for positive symptoms of schizophrenia, somnolence, and akathisia. The PANSS excited component score [P4 (Excitement), P7 (Hostility), G4 (Tension), G8 (Uncooperativeness), and G14 (Poor impulse control)], and the Personal and Social Performance scale disturbing and aggressive behavior domain were also assessed. Of the 147 patients who received aripiprazole lauroxil 882 mg and with a baseline PANSS Hostility item P7 more than 1, there was a significant (P<0.05) improvement versus placebo on the PANSS Hostility item P7 score by mixed-model repeated-measures at the end of the study, which remained significant when PANSS-positive symptoms and somnolence or akathisia were included as additional covariates. The proportion with PANSS Hostility item P7 more than 1 at endpoint was significantly (P<0.05) lower with aripiprazole lauroxil versus placebo (53.6, 46.1, and 66.3% for 441, 882 mg, and placebo). A significant (P<0.05) improvement was found with aripiprazole lauroxil versus placebo for change from baseline in the PANSS excited component score. The proportion of patients with aggressive behavior on the Personal and Social Performance scale was significantly (P<0.05) lower for aripiprazole lauroxil: 30.0% for 441 mg versus 44.1% for placebo (P=0.006) and 22.2% for 881 mg (P<0.001 versus placebo). Treatment with aripiprazole lauroxil resulted in decreases in agitation and hostility in patients

  16. 10 CFR 39.37 - Physical inventory.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Physical inventory. 39.37 Section 39.37 Energy NUCLEAR REGULATORY COMMISSION LICENSES AND RADIATION SAFETY REQUIREMENTS FOR WELL LOGGING Equipment § 39.37 Physical inventory. Each licensee shall conduct a semi-annual physical inventory to account for all licensed...

  17. 10 CFR 39.37 - Physical inventory.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Physical inventory. 39.37 Section 39.37 Energy NUCLEAR REGULATORY COMMISSION LICENSES AND RADIATION SAFETY REQUIREMENTS FOR WELL LOGGING Equipment § 39.37 Physical inventory. Each licensee shall conduct a semi-annual physical inventory to account for all licensed...

  18. 10 CFR 39.37 - Physical inventory.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Physical inventory. 39.37 Section 39.37 Energy NUCLEAR REGULATORY COMMISSION LICENSES AND RADIATION SAFETY REQUIREMENTS FOR WELL LOGGING Equipment § 39.37 Physical inventory. Each licensee shall conduct a semi-annual physical inventory to account for all licensed...

  19. 40 CFR 52.993 - Emissions inventories.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Emissions inventories. 52.993 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Louisiana § 52.993 Emissions inventories. (a) The Governor of the State of Louisiana submitted the 1990 base year emission inventories for the Baton...

  20. 40 CFR 52.2350 - Emission inventories.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 5 2014-07-01 2014-07-01 false Emission inventories. 52.2350 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Utah § 52.2350 Emission inventories. (a) The Governor of the State of Utah submitted the 1990 base year emission inventory of ozone precursors,...

  1. 40 CFR 52.1125 - Emission inventories.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 4 2012-07-01 2012-07-01 false Emission inventories. 52.1125 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Massachusetts § 52.1125 Emission inventories... emission inventories for the Springfield nonattainment area and the Massachusetts portion of the...

  2. 40 CFR 52.384 - Emission inventories.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Emission inventories. 52.384 Section 52...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Connecticut § 52.384 Emission inventories. (a) The Governor's designee for the State of Connecticut submitted the 1990 base year emission inventories for...

  3. 40 CFR 52.993 - Emissions inventories.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Emissions inventories. 52.993 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Louisiana § 52.993 Emissions inventories. (a) The Governor of the State of Louisiana submitted the 1990 base year emission inventories for the Baton...

  4. 40 CFR 52.348 - Emission inventories.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Emission inventories. 52.348 Section 52...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Colorado § 52.348 Emission inventories. (a) The Governor of the State of Colorado submitted the 1990 carbon monoxide base year emission inventories for...

  5. 40 CFR 52.1125 - Emission inventories.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 4 2013-07-01 2013-07-01 false Emission inventories. 52.1125 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Massachusetts § 52.1125 Emission inventories... emission inventories for the Springfield nonattainment area and the Massachusetts portion of the...

  6. 40 CFR 52.1125 - Emission inventories.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 4 2014-07-01 2014-07-01 false Emission inventories. 52.1125 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Massachusetts § 52.1125 Emission inventories... emission inventories for the Springfield nonattainment area and the Massachusetts portion of the...

  7. 40 CFR 52.384 - Emission inventories.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Emission inventories. 52.384 Section 52...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Connecticut § 52.384 Emission inventories. (a) The Governor's designee for the State of Connecticut submitted the 1990 base year emission inventories for...

  8. 40 CFR 52.384 - Emission inventories.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Emission inventories. 52.384 Section 52...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Connecticut § 52.384 Emission inventories. (a) The Governor's designee for the State of Connecticut submitted the 1990 base year emission inventories for...

  9. 40 CFR 52.1036 - Emission inventories.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 4 2012-07-01 2012-07-01 false Emission inventories. 52.1036 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Maine § 52.1036 Emission inventories. (a) The Governor's designee for the State of Maine submitted 1990 base year emission inventories for the Knox...

  10. 40 CFR 52.348 - Emission inventories.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Emission inventories. 52.348 Section 52...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Colorado § 52.348 Emission inventories. (a) The Governor of the State of Colorado submitted the 1990 carbon monoxide base year emission inventories for...

  11. 40 CFR 52.2350 - Emission inventories.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 5 2013-07-01 2013-07-01 false Emission inventories. 52.2350 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Utah § 52.2350 Emission inventories. (a) The Governor of the State of Utah submitted the 1990 base year emission inventory of ozone precursors,...

  12. 40 CFR 52.993 - Emissions inventories.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 3 2011-07-01 2011-07-01 false Emissions inventories. 52.993 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Louisiana § 52.993 Emissions inventories. (a) The Governor of the State of Louisiana submitted the 1990 base year emission inventories for the Baton...

  13. 40 CFR 52.2350 - Emission inventories.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Emission inventories. 52.2350 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Utah § 52.2350 Emission inventories. (a) The Governor of the State of Utah submitted the 1990 base year emission inventory of ozone precursors,...

  14. 40 CFR 52.1125 - Emission inventories.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Emission inventories. 52.1125 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Massachusetts § 52.1125 Emission inventories... emission inventories for the Springfield nonattainment area and the Massachusetts portion of the...

  15. 40 CFR 52.2350 - Emission inventories.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 5 2012-07-01 2012-07-01 false Emission inventories. 52.2350 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Utah § 52.2350 Emission inventories. (a) The Governor of the State of Utah submitted the 1990 base year emission inventory of ozone precursors,...

  16. 40 CFR 52.2350 - Emission inventories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Emission inventories. 52.2350 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Utah § 52.2350 Emission inventories. (a) The Governor of the State of Utah submitted the 1990 base year emission inventory of ozone precursors,...

  17. 40 CFR 52.348 - Emission inventories.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 3 2011-07-01 2011-07-01 false Emission inventories. 52.348 Section 52...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Colorado § 52.348 Emission inventories. (a) The Governor of the State of Colorado submitted the 1990 carbon monoxide base year emission inventories for...

  18. 40 CFR 52.384 - Emission inventories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Emission inventories. 52.384 Section 52...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Connecticut § 52.384 Emission inventories. (a) The Governor's designee for the State of Connecticut submitted the 1990 base year emission inventories for...

  19. 40 CFR 52.384 - Emission inventories.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 3 2011-07-01 2011-07-01 false Emission inventories. 52.384 Section 52...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Connecticut § 52.384 Emission inventories. (a) The Governor's designee for the State of Connecticut submitted the 1990 base year emission inventories for...

  20. 40 CFR 52.993 - Emissions inventories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Emissions inventories. 52.993 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Louisiana § 52.993 Emissions inventories. (a) The Governor of the State of Louisiana submitted the 1990 base year emission inventories for the Baton...

  1. 40 CFR 52.348 - Emission inventories.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Emission inventories. 52.348 Section 52...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Colorado § 52.348 Emission inventories. (a) The Governor of the State of Colorado submitted the 1990 carbon monoxide base year emission inventories for...

  2. 40 CFR 52.348 - Emission inventories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Emission inventories. 52.348 Section 52...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Colorado § 52.348 Emission inventories. (a) The Governor of the State of Colorado submitted the 1990 carbon monoxide base year emission inventories for...

  3. 40 CFR 52.993 - Emissions inventories.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Emissions inventories. 52.993 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Louisiana § 52.993 Emissions inventories. (a) The Governor of the State of Louisiana submitted the 1990 base year emission inventories for the Baton...

  4. 40 CFR 52.1125 - Emission inventories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Emission inventories. 52.1125 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Massachusetts § 52.1125 Emission inventories... emission inventories for the Springfield nonattainment area and the Massachusetts portion of the...

  5. 40 CFR 52.1036 - Emission inventories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Implementation Plan (SIP). The 2002 base year emission inventory requirement of 40 CFR 51.915 has been satisfied... Governor's designee for the State of Maine submitted 1990 base year emission inventories for the Knox and... base year emission inventory for the Portland area was submitted on June 9, 2005. The 1990 base...

  6. 40 CFR 52.1036 - Emission inventories.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Implementation Plan (SIP). The 2002 base year emission inventory requirement of 40 CFR 51.915 has been satisfied... Governor's designee for the State of Maine submitted 1990 base year emission inventories for the Knox and... base year emission inventory for the Portland area was submitted on June 9, 2005. The 1990 base...

  7. 40 CFR 52.1036 - Emission inventories.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Implementation Plan (SIP). The 2002 base year emission inventory requirement of 40 CFR 51.915 has been satisfied... Governor's designee for the State of Maine submitted 1990 base year emission inventories for the Knox and... base year emission inventory for the Portland area was submitted on June 9, 2005. The 1990 base...

  8. Readability of the Personality Inventory for Children.

    ERIC Educational Resources Information Center

    Barad, Susan J.; Hughes, Honore M.

    1984-01-01

    Applied three readability formulas differing in criterion for comprehension (50-100 percent) to the Personality Inventory for Children (PIC), Revised Format, and to abbreviated forms of the inventory. Results showed that for each method of analysis, readability of abbreviated forms approximates readability of the entire inventory. (LLL)

  9. 75 FR 82095 - Service Contracts Inventory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-29

    ... Doc No: 2010-32828] NUCLEAR REGULATORY COMMISSION [NRC-2010-0394] Service Contracts Inventory AGENCY... Regulatory Commission (NRC) is providing for public information its Inventory of Contracts for Services for Fiscal Year (FY) 2010. The inventory includes service contract actions over $25,000 that were awarded...

  10. 77 FR 5280 - Service Contracts Inventory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-02

    ... COMMISSION Service Contracts Inventory AGENCY: Nuclear Regulatory Commission. ACTION: Notice of availability... Contracts for Services for Fiscal Year (FY) 2011. The inventory includes service contract actions over $25... . The Inventory of Contracts for Services for FY 2011 can be accessed under ADAMS accession...

  11. 78 FR 10642 - Service Contracts Inventory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-14

    ... COMMISSION Service Contracts Inventory AGENCY: Nuclear Regulatory Commission. ACTION: Notice of availability... Contracts for Services for Fiscal Year (FY) 2012. The inventory includes service contract actions over $25... document is referenced. The Inventory of Contracts for Services for FY 2012 can be accessed under...

  12. 48 CFR 1845.508 - Physical inventories.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Physical inventories. 1845.508 Section 1845.508 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... Contractors 1845.508 Physical inventories. NASA contractors shall reconcile inventories with the...

  13. Psychometric Analysis of the Appreciative Advising Inventory

    ERIC Educational Resources Information Center

    Crone, Nancy J.

    2013-01-01

    The Appreciative Advising Inventory is an instrument created for use in academic advising. The inventory helps the advisor get to know and understand the student, which in turn allows the advisor to better assist the student. This research provides a psychometric analysis of the Appreciative Advising Inventory to measure its validity and…

  14. 27 CFR 17.167 - Inventories.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Inventories. 17.167... PRODUCTS Records § 17.167 Inventories. (a) Distilled spirits. The “on hand” figures reported in Part II of TTB Form 5154.2 shall be verified by physical inventories taken as of the end of each quarter in...

  15. 42 CFR 35.41 - Inventory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Inventory. 35.41 Section 35.41 Public Health PUBLIC... STATION MANAGEMENT Disposal of Money and Effects of Deceased Patients § 35.41 Inventory. Promptly after the death of a patient in a station or hospital of the Service, an inventory of his money and...

  16. 30 CFR 220.032 - Inventories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Inventories. 220.032 Section 220.032 Mineral... Inventories. (a) The lessee is responsible for NPSL materiel and shall make proper and timely cost and credit... operations. The accumulation of surplus stocks shall be avoided by proper materiel control, inventory...

  17. 27 CFR 17.167 - Inventories.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Inventories. 17.167... PRODUCTS Records § 17.167 Inventories. (a) Distilled spirits. The “on hand” figures reported in Part II of TTB Form 5154.2 shall be verified by physical inventories taken as of the end of each quarter in...

  18. 27 CFR 22.162 - Inventories.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Inventories. 22.162... Inventories. Each permittee shall take a physical inventory of the tax-free and recovered alcohol in its possession semi-annually for the periods ending June 30 and December 31 of each year; or other...

  19. 26 CFR 1.1374-7 - Inventory.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Inventory. 1.1374-7 Section 1.1374-7 Internal... TAXES Small Business Corporations and Their Shareholders § 1.1374-7 Inventory. (a) Valuation. The fair market value of the inventory of an S corporation on the first day of the recognition period equals...

  20. 21 CFR 1303.24 - Inventory allowance.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Inventory allowance. 1303.24 Section 1303.24 Food... Quotas § 1303.24 Inventory allowance. (a) For the purpose of determining individual manufacturing quotas... sufficient to maintain an inventory equal to, (1) For current manufacturers, 50 percent of his...

  1. 27 CFR 22.162 - Inventories.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Inventories. 22.162... Inventories. Each permittee shall take a physical inventory of the tax-free and recovered alcohol in its possession semi-annually for the periods ending June 30 and December 31 of each year; or other...

  2. 42 CFR 35.41 - Inventory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Inventory. 35.41 Section 35.41 Public Health PUBLIC... STATION MANAGEMENT Disposal of Money and Effects of Deceased Patients § 35.41 Inventory. Promptly after the death of a patient in a station or hospital of the Service, an inventory of his money and...

  3. 21 CFR 1303.24 - Inventory allowance.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Inventory allowance. 1303.24 Section 1303.24 Food... Quotas § 1303.24 Inventory allowance. (a) For the purpose of determining individual manufacturing quotas... sufficient to maintain an inventory equal to, (1) For current manufacturers, 50 percent of his...

  4. 30 CFR 1220.032 - Inventories.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Inventories. 1220.032 Section 1220.032 Mineral... GAS LEASES § 1220.032 Inventories. (a) The lessee is responsible for NPSL materiel and shall make... proper materiel control, inventory and purchasing. The lessee shall make timely disposition of idle...

  5. 41 CFR 109-27.5007 - Physical inventories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Physical inventories...-INVENTORY MANAGEMENT 27.50-Inventory Management Policies, Procedures, and Guidelines § 109-27.5007 Physical inventories....

  6. 41 CFR 109-27.5007 - Physical inventories.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Physical inventories...-INVENTORY MANAGEMENT 27.50-Inventory Management Policies, Procedures, and Guidelines § 109-27.5007 Physical inventories....

  7. Solution-dispersed CuO nanoparticles anode buffer layer: Effect of ultrasonic agitation duration on photovoltaic performance

    NASA Astrophysics Data System (ADS)

    Sabri, Nasehah Syamin; Yap, Chi Chin; Yahaya, Muhammad; Salleh, Muhamad Mat; Jumali, Mohammad Hafizuddin Haji

    2016-11-01

    The performance of inverted type hybrid organic solar cell based on poly(3-hexyltheopene):[6,6]-phenyl C61-butyric acid methyl ester (P3HT:PCBM) can be improved by adding an anode buffer layer of copper oxide (CuO). CuO that serves as an electron blocking layer which could effectively reduce the charge recombination at the photoactive layer (P3HT:PCBM)/silver (Ag) interfaces. At the same time, Cuo anode buffer layer could accelerate the holes collection from the photoactive layer to the top electrode. In this study we investigated the effects of ultrasonic agitation duration in preparation of solution-dispersed CuO anode buffer layer on the performance of the devices with a configuration of fluorine tin oxide (FTO)/zinc oxide (ZnO) nanorod arrays/P3HT:PCBM/ CuO/Ag. Different durations of ultrasonic agitation (0, 5, 15 and 25 min) were used for CuO nanoparticles solution dispersion to obtain the optimum particle size distribution of CuO. It was found that the smallest average particle size of CuO was obtained by applying the ultrasonic agitation for longest duration of 25 min. The highest power conversion efficiency of 1.22% was recorded from the device incorporating with CuO anode buffer layer with the smallest average particle size. It is believed that CuO anode buffer layer with the smallest average particle size had the least agglomerates, thus leading to better film formation and contact surface area.

  8. Changes in QTc Interval in the Citalopram for Agitation in Alzheimer's Disease (CitAD) Randomized Trial

    PubMed Central

    Drye, Lea T.; Spragg, David; Devanand, D. P.; Frangakis, Constantine; Marano, Christopher; Meinert, Curtis L.; Mintzer, Jacobo E.; Munro, Cynthia A.; Pelton, Gregory; Pollock, Bruce G.; Porsteinsson, Anton P.; Rabins, Peter V.; Rosenberg, Paul B.; Schneider, Lon S.; Shade, David M.; Weintraub, Daniel; Yesavage, Jerome; Lyketsos, Constantine G.

    2014-01-01

    Background A Food and Drug Administration (FDA) safety communication in August 2011 warned that citalopram was associated with a dose dependent risk of QT prolongation and recommended dose restriction in patients over the age of 60 but did not provide data for this age group. Methods CitAD was a randomized, double-masked, placebo-controlled, multicenter clinical trial for agitation in Alzheimer's disease (AD). Participants were assigned to citalopram (target dose of 30 mg/day) or placebo in a 1∶1 ratio. 186 people, 181 of whom were over the age of 60, having probable AD with clinically significant agitation were recruited from September 2009 to January 2013. After the FDA safety communication about citalopram, ECG was added to the required study procedures before enrollment and repeated at week 3 to monitor change in QTc interval. Forty-eight participants were enrolled after enhanced monitoring began. Results Citalopram treatment was associated with a larger increase in QTc interval than placebo (difference in week 3 QTc adjusting for baseline QTc: 18.1 ms [95% CI: 6.1, 30.1]; p = 0.004). More participants in the citalopram group had an increase ≥30 ms from baseline to week 3 (7 in citalopram versus 1 in placebo; Fisher's exact p = 0.046), but only slightly more in the citalopram group met a gender-specific threshold for prolonged QTc (450 ms for males; 470 ms for females) at any point during follow-up (3 in citalopram versus 1 in placebo, Fisher's exact p = 0.611). One of the citalopram participants who developed prolonged QTc also displayed ventricular bigeminy. No participants in either group had a cardiovascular-related death. Conclusion Citalopram at 30 mg/day was associated with improvement in agitation in patients with AD but was also associated with QT prolongation. Trial Registration ClinicalTrials.gov NCT00898807 PMID:24914549

  9. Dependence of penicillium chrysogenum growth, morphology, vacuolation, and productivity in fed-batch fermentations on impeller type and agitation intensity

    PubMed

    J sten P; Paul; Nienow; Thomas

    1998-09-20

    The influence of the agitation conditions on the growth, morphology, vacuolation, and productivity of Penicillium chrysogenum has been examined in 6 L fed-batch fermentations. A standard Rushton turbine, a four-bladed paddle, and a six-bladed pitched blade impeller were compared. Power inputs per unit volume of liquid, P/VL, ranged from 0.35 to 7.4 kW/m3. The same fermentation protocol was used in each fermentation, including holding the dissolved oxygen concentration above 40% air saturation by gas blending. The mean projected area (for all dispersed types, including clumps) and the clump roughness were used to characterize the morphology. Consideration of clumps was vital as these were the predominant morphological form. For a given impeller, the batch-phase specific growth rates and the overall biomass concentrations increased with agitation intensity. Higher fragmentation at higher speeds was assumed to have promoted growth through increased formation of new growing tips. The mean projected area increased during the rapid growth phase followed by a sharp decrease to a relatively constant value dependent on the agitation conditions. The higher the speed, the lower the projected area for a given impeller type. The proportion by volume of hyphal vacuoles and empty regions decreased with speed, possibly due to fragmentation in the vacuolated regions. The specific penicillin production rate was generally higher with lower impeller speed for a given impeller type. The highest value of penicillin production as well as its rate was obtained using the Rushton turbine impeller at the lowest speed. At given P/VL, changes in morphology, specific growth rate, and specific penicillin production rate depended on impeller geometry. The morphological data could be correlated with either tip speed or the "energy dissipation/circulation function," but a reasonable correlation of the specific growth rate and specific production rate was only possible with the latter. Copyright

  10. Insights into Kinetics of Agitation-Induced Aggregation of Hen Lysozyme under Heat and Acidic Conditions from Various Spectroscopic Methods

    PubMed Central

    Chaari, Ali; Fahy, Christine; Chevillot-Biraud, Alexandre; Rholam, Mohamed

    2015-01-01

    Protein misfolding and amyloid formation are an underlying pathological hallmark in a number of prevalent diseases of protein aggregation ranging from Alzheimer’s and Parkinson’s diseases to systemic lysozyme amyloidosis. In this context, we have used complementary spectroscopic methods to undertake a systematic study of the self-assembly of hen egg-white lysozyme under agitation during a prolonged heating in acidic pH. The kinetics of lysozyme aggregation, monitored by Thioflavin T fluorescence, dynamic light scattering and the quenching of tryptophan fluorescence by acrylamide, is described by a sigmoid curve typical of a nucleation-dependent polymerization process. Nevertheless, we observe significant differences between the values deduced for the kinetic parameters (lag time and aggregation rate). The fibrillation process of lysozyme, as assessed by the attenuated total reflection-Fourier transform infrared spectroscopy, is accompanied by an increase in the β-sheet conformation at the expense of the α-helical conformation but the time-dependent variation of the content of these secondary structures does not evolve as a gradual transition. Moreover, the tryptophan fluorescence-monitored kinetics of lysozyme aggregation is described by three phases in which the temporal decrease of the tryptophan fluorescence quantum yield is of quasilinear nature. Finally, the generated lysozyme fibrils exhibit a typical amyloid morphology with various lengths (observed by atomic force microscopy) and contain exclusively the full-length protein (analyzed by highly performance liquid chromatography). Compared to the data obtained by other groups for the formation of lysozyme fibrils in acidic pH without agitation, this work provides new insights into the structural changes (local, secondary, oligomeric/fibrillar structures) undergone by the lysozyme during the agitation-induced formation of fibrils. PMID:26571264

  11. Influence of intergrain interactions and thermal agitation on microwave-assisted magnetization switching behavior of granular magnetic film

    NASA Astrophysics Data System (ADS)

    Okamoto, Satoshi; Kikuchi, Nobuaki; Kitakami, Osamu; Shimatsu, Takehito

    2017-02-01

    Microwave-assisted magnetization switching (MAS) in a granular magnetic film is examined by computer simulation. Contrary to the macrospin calculation and the experiments on single magnetic dots reported so far, in which the switching field linearly decreases with increasing rf frequency and then sharply increases at the critical frequency, the granular film exhibits considerably broad MAS behavior against the rf frequency. This broad MAS behavior is mainly caused by the dispersion of magnetic properties and thermal agitation. On the other hand, intergrain dipolar and exchange interactions enhance the MAS effect in the granular film and suppress the MAS broadening.

  12. Developing an action concept inventory

    NASA Astrophysics Data System (ADS)

    McGinness, Lachlan P.; Savage, C. M.

    2016-06-01

    We report on progress towards the development of an Action Concept Inventory (ACI), a test that measures student understanding of action principles in introductory mechanics and optics. The ACI also covers key concepts of many-paths quantum mechanics, from which classical action physics arises. We used a multistage iterative development cycle for incorporating expert and student feedback into successive revisions of the ACI. The student feedback, including think-aloud interviews, enabled us to identify their misconceptions about action physics.

  13. Waste management and chemical inventories

    SciTech Connect

    Gleckler, B.P.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report summarizes the classification and handling of waste at the Hanford Site. Waste produced at the Hanford Site is classified as either radioactive, nonradioactive, or mixed waste. Radioactive wastes are further categorized as transuranic, high-level, and low-level. Mixed waste may contain both radioactive and hazardous nonradioactive substances. This section describes waste management practices and chemical inventories at the site.

  14. A Methodology for Developing Diagnostic Concept Inventories

    NASA Astrophysics Data System (ADS)

    Lindell, Rebecca

    2006-12-01

    Since the development of the Force Concept Inventory, there as been a heightened interest in developing other concept inventories that not only assess if students understand a phenomena, but also diagnose specific alternative understandings. Unfortunately, there is no clear-cut methodology on how to construct such inventories. One of the difficulties is that only some parts of test development theory are appropriate for such concept inventories. This is due to the concept inventories being distracter driven, where test-takers do not randomly choose an incorrect answer. In this poster, I will present a methodology for developing diagnostic concept inventories, which combines traditional psychometric theory with modern theories of concentration and model analysis. An example of how this methodology was utilized to develop the successful Lunar Phases Concept Inventory (LPCI) will also be given.

  15. Monitoring the progress of emission inventories

    SciTech Connect

    Levy, J.A. Jr.; Solomon, D.; Husk, M.; Irving, B.; Kruger, D.; Levin. L.

    2006-12-15

    This issue of EM contains three articles which focus on the latest improvements on the emissions inventory process. The first, 'Building the national emissions inventory: challenges and plans for improvements' by Doug Solomon and Martin Husk (pages 8-11), looks at the US national emissions inventory. The next, 'Greenhouse gas inventories - a historical perspective and assessment of improvements since 1990' by Bill Irving and Dina Kruger (pages 12-19) assesses improvements in national and international greenhouse gas emissions inventories over the last 15 years. The third article, 'The global mercury emissions inventory' by Leonard Levin (pages 20-25) gives an overview of the challenges associated with conducting a worldwide inventory of mercury emissions.

  16. Galantamine Response Associates with Agitation and the Prefrontal Cortex in Patients with Alzheimer's Disease.

    PubMed

    Nakayama, Sachiko; Suda, Akimitsu; Nakanishi, Atsushi; Motoi, Yumiko; Hattori, Nobutaka

    2017-01-01

    Behavioral and psychological symptoms of dementia (BPSD) occur in up to 80% of AD patients and represent one of the largest factors contributing to caregiver burden. To analyze the effect of galantamine on BPSD and caregiver burden, we treated a total of 50 patients with mild AD for 12 weeks and evaluated them using the Neuropsychiatric Inventory (NPI) and Japanese version of the Zarit Caregiver Burden Interview (ZBI). We also performed regional cerebral blood flow single photon emission computed tomography (rCBF SPECT) at baseline using three-dimensional sterotatic surface projections. Total NPI and ZBI scores did not significantly change after 12-week galantamine treatment. To identify the characteristics of patients who showed improvement after galantamine treatment, we divided patients into two groups, those with and those without sub-items on the NPI. Patients with aggression showed improvement in ZBI scores (p < 0.05). A comparison of rCBF SPECT between these two groups indicated that patients with aggression exhibited increased rCBF in the right prefrontal cortex compared with those without aggression. In a patient with aggression, 20-month treatment with galantamine inhibited increases in the rCBF area in the right prefrontal lobe. These results suggest that galantamine response may be related to aggression and dysfunction of the prefrontal cortex.

  17. The glass is not yet half empty: agitation but not Varroa treatment causes cognitive bias in honey bees.

    PubMed

    Schlüns, Helge; Welling, Helena; Federici, Julian René; Lewejohann, Lars

    2017-03-01

    Honey bees (Apis mellifera) are prone to judge an ambiguous stimulus negatively if they had been agitated through shaking which simulates a predator attack. Such a cognitive bias has been suggested to reflect an internal emotional state analogous to humans who judge more pessimistically when they do not feel well. In order to test cognitive bias experimentally, an animal is conditioned to respond to two different stimuli, where one is punished while the other is rewarded. Subsequently a third, ambiguous stimulus is presented and it is measured whether the subject responds as if it expects a reward or a punishment. Generally, it is assumed that negative experiences lower future expectations, rendering the animals more pessimistic. Here we tested whether a most likely negatively experienced formic acid treatment against the parasitic mite Varroa destructor also affects future expectations of honey bees. We applied an olfactory learning paradigm (i.e., conditioned proboscis extension response) using two odorants and blends of these odorants as the ambiguous stimuli. Unlike agitating honey bees, exposure to formic acid did not significantly change the response to the ambiguous stimuli in comparison with untreated bees. Overall evidence suggests that the commonest treatment against one of the most harmful bee pests has no detrimental effects on cognitive bias in honey bees.

  18. The effect of additives and mechanical agitation in surface modification of acrylic fibres by cutinase and esterase.

    PubMed

    Matamá, Teresa; Vaz, Filipe; Gübitz, Georg M; Cavaco-Paulo, Artur

    2006-01-01

    The surface of an acrylic fibre containing about 7% of vinyl acetate was modified using Fusarium solani pisi cutinase and a commercial esterase, Texazym PES. The effect of acrylic solvents and stabilising polyols on cutinase operational stability was studied. The half-life time of cutinase increased by 3.5-fold with the addition of 15% N,N-dimethylacetamide (DMA) and by 3-fold with 1M glycerol. The impact of additives and mechanical agitation in the protein adsorption and in the hydrolysis of vinyl acetate from acrylic fabric was investigated. The hydroxyl groups produced on the surface of the fibre were able to react specifically with Remazol Brilliant Blue R (cotton reactive dye) and to increase the colour of the acrylic-treated fabric. The best staining level was obtained with a high level of mechanical agitation and with the addition of 1% DMA. Under these conditions, the raise in the acrylic fabric colour depth was 30% for cutinase and 25% for Texazym. The crystallinity degree, determined by X-ray diffraction, was not significantly changed between control samples and samples treated with cutinase. The results showed that the outcome of the application of these enzymes depends closely on the reaction media conditions.

  19. Comparison of the Effect of Thiopental Sodium with Midazolam-ketamine on Post-tonsillectomy Agitation in Children.

    PubMed

    Toliyat, Maryam; Zangoee, Maliheh; Ahrari, Shahnaz; Zangoee, Reza

    2015-10-01

    The aim of this study was to determine the effect of thiopental sodium with that of midazolam-ketamine on relieving agitation after tonsillectomy in children. In a clinical trial, 50 children aged 5-10 years, candidates for tonsillectomy, were randomly divided into two 25-member groups. In the first group, thiopental sodium 5mg/kg/IV, and in the second group combination of midazolam 0.01 mg/kg/IV and ketamine 1 mg/kg/IV were used to induce anesthesia. The level of sedation was assessed after surgery with the Ramsay scale. There were no significant differences between the two groups in terms of heart rate, arterial oxygen pressure (PO2), and duration of anesthesia. The Ramsay sedation score was significantly higher in the thiopental sodium group than in the midazolam-ketamine group (P=0.01). Thiopental sodium can be more effective than the combination of midazolam-ketamine for controlling agitation after tonsillectomy in children.

  20. Progress in Treatment Development for Neuropsychiatric Symptoms in Alzheimer’s Disease: Focus on Agitation and Aggression. A Report from the EU/US/CTAD Task Force

    PubMed Central

    Soto, M.; Abushakra, S.; Cummings, J.; Siffert, J.; Robert, P.; Vellas, B.; Lyketsos, C.G.

    2015-01-01

    BACKGROUND The management of neuropsychiatric symptoms (NPS) such as agitation and aggression is a major priority in caring for people with Alzheimer’s disease (AD). Agitation and aggression (A/A) are among the most disruptive symptoms, and given their impact, they are increasingly an important target for development of effective treatments. Considerable progress has been made in the last years with a growing number of randomized controlled trials (RCTs) of drugs for NPS. The limited benefits reported in some RCTs may be accounted for by the absence of a biological link of the tested molecule to NPS and also by key methodological issues. In recent RCTs of A/A, a great heterogeneity design was found. Designing trials for dementia populations with NPS presents many challenges, including identification of appropriate participants for such trials, engagement and compliance of patients and caregivers in the trials and the choice of optimal outcome measures to demonstrate treatment effectiveness. The EU/US -CTAD Task Force, an international collaboration of investigators from academia, industry, non-profit foundations, and regulatory agencies met in Philadelphia on November 19, 2014 to address some of these challenges. Despite potential heterogeneity in clinical manifestations and neurobiology, agitation and aggression seems to be accepted as an entity for drug development. The field appears to be reaching a consensus in using both agitation and aggression (or other NPS)-specific quantitative measures plus a global rating of change for agitation outcomes based on clinician judgment as the main outcomes. PMID:26413494

  1. Managing Inventories of Heavy Actinides

    SciTech Connect

    Wham, Robert M; Patton, Bradley D

    2011-01-01

    The Department of Energy (DOE) has stored a limited inventory of heavy actinides contained in irradiated targets, some partially processed, at the Savannah River Site (SRS) and Oak Ridge National Laboratory (ORNL). The 'heavy actinides' of interest include plutonium, americium, and curium isotopes; specifically 242Pu and 244Pu, 243Am, and 244/246/248Cm. No alternate supplies of these heavy actinides and no other capabilities for producing them are currently available. Some of these heavy actinide materials are important for use as feedstock for producing heavy isotopes and elements needed for research and commercial application. The rare isotope 244Pu is valuable for research, environmental safeguards, and nuclear forensics. Because the production of these heavy actinides was made possible only by the enormous investment of time and money associated with defense production efforts, the remaining inventories of these rare nuclear materials are an important part of the legacy of the Nuclear Weapons Program. Significant unique heavy actinide inventories reside in irradiated Mark-18A and Mark-42 targets at SRS and ORNL, with no plans to separate and store the isotopes for future use. Although the costs of preserving these heavy actinide materials would be considerable, for all practical purposes they are irreplaceable. The effort required to reproduce these heavy actinides today would likely cost billions of dollars and encompass a series of irradiation and chemical separation cycles for at least 50 years; thus, reproduction is virtually impossible. DOE has a limited window of opportunity to recover and preserve these heavy actinides before they are disposed of as waste. A path forward is presented to recover and manage these irreplaceable National Asset materials for future use in research, nuclear forensics, and other potential applications.

  2. OSSA Space Station waste inventory

    NASA Technical Reports Server (NTRS)

    Rasmussen, Daryl N.; Johnson, Catherine C.; Bosley, John J.; Curran, George L.; Mains, Richard

    1987-01-01

    NASA's Office of Space Science and Applications has compiled an inventory of the types and quantities of the wastes that will be generated by the Space Station's initial operational phase in 35 possible mission scenarios. The objective of this study was the definition of waste management requirements for both the Space Station and the Space Shuttles servicing it. All missions, when combined, will produce about 5350 kg of gaseous, liquid and solid wastes every 90 days. A characterization has been made of the wastes in terms of toxicity, corrosiveness, and biological activity.

  3. Propagated fixed-bed mixed-acid fermentation: Part I: Effect of volatile solid loading rate and agitation at high pH.

    PubMed

    Golub, Kristina W; Forrest, Andrea K; Mercy, Kevin L; Holtzapple, Mark T

    2011-11-01

    Countercurrent fermentation is a high performing process design for mixed-acid fermentation. However, there are high operating costs associated with moving solids, which is an integral component of this configuration. This study investigated the effect of volatile solid loading rate (VSLR) and agitation in propagated fixed-bed fermentation, a configuration which may be more commercially viable. To evaluate the role of agitation on fixed-bed configuration performance, continuous mixing was compared with periodic mixing. VSLR was also varied and not found to affect acid yields. However, increased VSLR and liquid retention time did result in higher conversions, productivity, acid concentrations, but lower selectivities. Agitation was demonstrated to be important for this fermentor configuration, the periodically-mixed fermentation had the lowest conversion and yields. Operating at a high pH (∼9) contributed to the high selectivity to acetic acid, which might be industrially desirable but at the cost of lower yield compared to a neutral pH.

  4. Hanford inventory program user`s manual

    SciTech Connect

    Hinkelman, K.C.

    1994-09-12

    Provides users with instructions and information about accessing and operating the Hanford Inventory Program (HIP) system. The Hanford Inventory Program is an integrated control system that provides a single source for the management and control of equipment, parts, and material warehoused by Westinghouse Hanford Company in various site-wide locations. The inventory is comprised of spare parts and equipment, shop stock, special tools, essential materials, and convenience storage items. The HIP replaced the following systems; ACA, ASP, PICS, FSP, WSR, STP, and RBO. In addition, HIP manages the catalog maintenance function for the General Supplies inventory stocked in the 1164 building and managed by WIMS.

  5. Advanced Data Collection for Inventory Management

    NASA Technical Reports Server (NTRS)

    Opresko, G. A.; Leet, J. H.; Mcgrath, D. F.; Eidson, J.

    1987-01-01

    Bar-coding, radio-frequency, and voice-operated systems selected. Report discusses study of state-of-the-art in automated collection of data for management of large inventories. Study included comprehensive search of literature on data collection and inventory management, visits to existing automated inventory systems, and tours of selected supply and transportation facilities at Kennedy Space Center. Information collected analyzed in view of needs of conceptual inventory-management systems for Kennedy Space Center and for manned space station and other future space projects.

  6. Inventory accuracy in 60 days!

    PubMed

    Miller, G J

    1997-08-01

    Despite great advances in manufacturing technology and management science, thousands of organizations still don't have a handle on basic inventory accuracy. Many companies don't even measure it properly, or at all, and lack corrective action programs to improve it. This article offers an approach that has proven successful a number of times, when companies were quite serious about making improvements. Not only can it be implemented, but also it can likely be implemented within 60 days per area, if properly managed. The hardest part is selling people on the need to improve and then keeping them motivated. The net cost of such a program? Probably less than nothing, since the benefits gained usually far exceed the costs. Improved inventory accuracy can aid in enhancing customer service, determining purchasing and manufacturing priorities, reducing operating costs, and increasing the accuracy of financial records. This article also addresses the gap in contemporary literature regarding accuracy program features for repetitive, JIT, cellular, and process- and project-oriented environments.

  7. 10 CFR 75.32 - Initial inventory report.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Initial inventory report. 75.32 Section 75.32 Energy... AGREEMENT Reports § 75.32 Initial inventory report. (a) The initial inventory reporting date shall be the... inventory report is required. (b) The initial inventory report, to be submitted to the Commission...

  8. 26 CFR 1.1013-1 - Property included in inventory.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 11 2011-04-01 2011-04-01 false Property included in inventory. 1.1013-1... included in inventory. The basis of property required to be included in inventory is the last inventory... an inventory are stated in subpart D (section 471 and following), part II, subchapter E, chapter 1...

  9. 26 CFR 1.1013-1 - Property included in inventory.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Property included in inventory. 1.1013-1 Section... inventory. The basis of property required to be included in inventory is the last inventory value of such property in the hands of the taxpayer. The requirements with respect to the valuation of an inventory...

  10. 10 CFR 75.32 - Initial inventory report.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Initial inventory report. 75.32 Section 75.32 Energy... AGREEMENT Reports § 75.32 Initial inventory report. (a) The initial inventory reporting date shall be the... inventory report is required. (b) The initial inventory report, to be submitted to the Commission...

  11. 41 CFR 109-27.5007-2 - Inventory adjustments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Inventory adjustments... PROCUREMENT 27-INVENTORY MANAGEMENT 27.50-Inventory Management Policies, Procedures, and Guidelines § 109-27.5007-2 Inventory adjustments. Discrepancies between physical inventories and stock records shall...

  12. Accumulation of dibenzocyclooctadiene lignans in agar cultures and in stationary and agitated liquid cultures of Schisandra chinensis (Turcz.) Baill.

    PubMed

    Szopa, Agnieszka; Kokotkiewicz, Adam; Marzec-Wróblewska, Urszula; Bucinski, Adam; Luczkiewicz, Maria; Ekiert, Halina

    2016-05-01

    Schisandra chinensis plant in vitro cultures were maintained on Murashige and Skoog (MS) medium supplemented with 3 mg/l 6-benzyladenine (BA) and 1 mg/l 1-naphthaleneacetic acid (NAA) in an agar system and also in two different liquid systems: stationary and agitated. Liquid cultures were grown in batch (30 and 60 days) and fed-batch modes. In the methanolic extracts from lyophilized biomasses and in the media, quantification of fourteen dibenzocyclooctadiene lignans identified based on co-chromatography with authentic standards using high-performance liquid chromatography with diode array detection (HPLC-DAD) and/or liquid chromatography with diode array detection and electrospray ionization mass spectrometry (LC-DAD-ESI-MS) methods. For comparison purposes, phytochemical analyses were performed of lignans in the leaves and fruits of the parent plant. The main lignans detected in the biomass extracts from all the tested systems were schisandrin (max. 65.62 mg/100 g dry weight (DW)), angeloyl-/tigloylgomisin Q (max. 49.73 mg/100 g DW), deoxyschisandrin (max. 43.65 mg/100 g DW), and gomisin A (max. 34.36 mg/100 g DW). The highest total amounts of lignans in the two tested stationary systems were found in extracts from the biomass harvested after 30 days of batch cultivation: 237.86 mg/100 g DW and 274.65 mg/100 g DW, respectively. In the agitated culture, the total content reached a maximum value of 244.80 mg/100 g DW after 60 days of the fed-batch mode of cultivation. The lignans were not detected in the media. This is the first report which documents the potential usefulness of S. chinensis shoot cultures cultivated in liquid systems for practical purposes.

  13. Effect of Mechanical Agitation on Cationic Liposome Transport across an Unstirred Water Layer in Caco-2 Cells.

    PubMed

    Kono, Yusuke; Iwasaki, Ayu; Matsuoka, Kenta; Fujita, Takuya

    2016-01-01

    To develop an effective oral delivery system for plasmid DNA (pDNA) using cationic liposomes, it is necessary to clarify the characteristics of uptake and transport of cationic liposome/pDNA complexes into the intestinal epithelium. In particular, evaluation of the involvement of an unstirred water layer (UWL), which is a considerable permeability barrier, in cationic liposome transport is very important. Here, we investigated the effects of a UWL on the transfection efficiency of cationic liposome/pDNA complexes into a Caco-2 cell monolayer. When Caco-2 cells were transfected with cationic liposome/pDNA complexes in shaking cultures to reduce the thickness of the UWL, gene expression was significantly higher in Caco-2 cells compared with static cultures. We also found that this enhancement of gene expression by shaking was not attributable to activation of transcription factors such as activator protein-1 and nuclear factor-kappaB (NF-κB). In addition, the increase in gene expression by mechanical agitation was observed at all charge ratios (1.5, 2.3, 3.1, 4.5) of cationic liposome/pDNA complexes. Transport experiments using Transwells demonstrated that mechanical agitation increased the uptake of cationic liposome/pDNA complexes by Caco-2 cells, whereas transport of the complexes across a Caco-2 cell monolayer did not occurr. Moreover, the augmentation of the gene expression of cationic liposome/pDNA complexes by shaking was observed in Madin-Darby canine kidney cells. These results indicate that a UWL greatly affects the uptake and transfection efficiency of cationic liposome/pDNA complexes into an epithelial monolayer in vitro.

  14. Tandem air-agitated liquid-liquid microextraction as an efficient method for determination of acidic drugs in complicated matrices.

    PubMed

    Bazregar, Mohammad; Rajabi, Maryam; Yamini, Yadollah; Asghari, Alireza; Hemmati, Maryam

    2016-04-21

    A rapid and simple microextraction method with a high sample clean-up, termed as tandem air-agitated liquid-liquid microextraction (TAALLME), is described. This method is based upon the tandem implementation of the air-agitated liquid-liquid microextraction (AALLME), and this approach improves the applicability of the dispersive liquid-liquid microextraction (DLLME) methods in complicated matrices. With very simple tools, the three non-steroidal anti-inflammatory drugs diclofenac, ibuprofen, and mefenamic acid were efficiently extracted, with an overall extraction time of 7 min. By performing the first AALLME, these acidic analytes, contained in an aqueous sample solution (donor phase, 8.0 mL), were extracted into the organic solvent (1,2-dichloroethane, 37 μL), and their simple back-extraction into the aqueous acceptor solution (pH, 10.01, 51 μL) was obtained in 2 min by a second implementation of AALLME. Response surface methodology (RSM) was used for optimization of the experimental parameters. The pH values 2.94 and 10.01 were obtained for the donor and acceptor phases, respectively, and the volumes 99.5 and 51 μL were obtained for the organic solvent and the acceptor phase, respectively, as the optimal extraction conditions. Under the optimized conditions, tandem AALLME-HPLC-UV provided a good linearity in the range of 0.5-4000 ng mL(-1), limits of detection (0.1-0.3 ng mL(-1)), extraction repeatabilities (relative standard deviations (RSDs) below 7.7%, n = 5), and the enrichment factors (EFs) of 80-104. Finally, the applicability of the proposed method was evaluated by the extraction and determination of the drugs under study in the wastewater and human plasma samples.

  15. Global emissions inventories to aid atmospheric modelers

    NASA Astrophysics Data System (ADS)

    Graedel, T. E.

    Computer projections of changes in global atmospheric chemistry could become more accurate and more easily compared with the availability of standard global emissions inventories. Starting in 1994, the Global Emissions Inventory Activity (GEIA) began to finalize gridded global emissions inventories and distribute them to atmospheric scientists. GEIA operates under the auspices of the International Global Atmospheric Chemistry (IGAC) Project, a cooperative effort of several hundred atmospheric scientists from more than 30 countries. The purpose of the IGAC Project is to measure, understand, and predict changes in global atmospheric chemistry, particularly those contributing to global problems such as acid rain, depletion of stratospheric ozone, greenhouse warming, and increased oxidant levels that damage biota.A 1992 survey by participants in the GEIA project [Graedel et al., 1993] showed that suitable emissions inventories are rarely available. The chlorofluorocarbon inventory, regarded as well quantified, was unavailable in gridded form. Inventories for CO2, CH4, NOx, SO2, reduced sulfur, and radon were regarded as having excess uncertainty, inadequate spatial resolution, or both; inventories for other chemical species were sketchy or nonexistent. Temporal resolution was almost uniformly poor. The survey made it clear that internally consistent, rigorously developed, gridded inventories with adequate spatial and temporal resolution would be valuable.

  16. 27 CFR 24.266 - Inventory losses.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... fermentation; or the loss exceeds six percent of the sparkling wine produced by fermentation in bottles; or the... OF THE TREASURY LIQUORS WINE Losses of Wine § 24.266 Inventory losses. (a) General. The proprietor shall take a physical inventory of all untaxpaid wine on-hand on bonded wine premises as of the close...

  17. 27 CFR 24.266 - Inventory losses.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... fermentation; or the loss exceeds six percent of the sparkling wine produced by fermentation in bottles; or the... OF THE TREASURY ALCOHOL WINE Losses of Wine § 24.266 Inventory losses. (a) General. The proprietor shall take a physical inventory of all untaxpaid wine on-hand on bonded wine premises as of the close...

  18. 27 CFR 24.266 - Inventory losses.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... fermentation; or the loss exceeds six percent of the sparkling wine produced by fermentation in bottles; or the... OF THE TREASURY LIQUORS WINE Losses of Wine § 24.266 Inventory losses. (a) General. The proprietor shall take a physical inventory of all untaxpaid wine on-hand on bonded wine premises as of the close...

  19. 27 CFR 24.266 - Inventory losses.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... fermentation; or the loss exceeds six percent of the sparkling wine produced by fermentation in bottles; or the... OF THE TREASURY ALCOHOL WINE Losses of Wine § 24.266 Inventory losses. (a) General. The proprietor shall take a physical inventory of all untaxpaid wine on-hand on bonded wine premises as of the close...

  20. 27 CFR 24.266 - Inventory losses.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... fermentation; or the loss exceeds six percent of the sparkling wine produced by fermentation in bottles; or the... OF THE TREASURY LIQUORS WINE Losses of Wine § 24.266 Inventory losses. (a) General. The proprietor shall take a physical inventory of all untaxpaid wine on-hand on bonded wine premises as of the close...

  1. 27 CFR 19.329 - Production inventories.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Production inventories. 19..., DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Production Inventories § 19.329 Production... other vessels in the production account at the close of each calendar quarter and at such other times...

  2. U.S. Emissions Inventory 1997

    EPA Pesticide Factsheets

    View the 1997 U.S. Greenhouse Gas Inventory developed by the U.S. Government to meet U.S. commitments under the Framework Convention on Climate Change (UNFCCC). This version of the inventory covers the period from 1990 to 1995.

  3. 27 CFR 19.333 - Physical inventories.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Physical inventories. 19.333 Section 19.333 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU... part. TTB may require additional inventories at any time. (26 U.S.C. 5201)...

  4. 27 CFR 19.312 - Physical inventories.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Physical inventories. 19.312 Section 19.312 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU... additional inventories be taken at any time. (26 U.S.C. 5201) Rules for Redistillation...

  5. 27 CFR 19.333 - Physical inventories.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Physical inventories. 19.333 Section 19.333 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU... part. TTB may require additional inventories at any time. (26 U.S.C. 5201)...

  6. Psychometric Properties of the HEXACO Personality Inventory

    ERIC Educational Resources Information Center

    Lee, Kibeom; Ashton, Michael C.

    2004-01-01

    We introduce a personality inventory designed to measure six major dimensions of personality derived from lexical studies of personality structure. The HEXACO Personality Inventory (HEXACO-PI) consists of 24 facet-level personality trait scales that define the six personality factors named Honesty-Humility (H), Emotionality (E), Extraversion (X),…

  7. 10 CFR 34.29 - Quarterly inventory.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Quarterly inventory. 34.29 Section 34.29 Energy NUCLEAR REGULATORY COMMISSION LICENSES FOR INDUSTRIAL RADIOGRAPHY AND RADIATION SAFETY REQUIREMENTS FOR INDUSTRIAL... physical inventory to account for all sealed sources and for devices containing depleted uranium...

  8. 10 CFR 34.29 - Quarterly inventory.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Quarterly inventory. 34.29 Section 34.29 Energy NUCLEAR REGULATORY COMMISSION LICENSES FOR INDUSTRIAL RADIOGRAPHY AND RADIATION SAFETY REQUIREMENTS FOR INDUSTRIAL... physical inventory to account for all sealed sources and for devices containing depleted uranium...

  9. 10 CFR 34.29 - Quarterly inventory.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Quarterly inventory. 34.29 Section 34.29 Energy NUCLEAR REGULATORY COMMISSION LICENSES FOR INDUSTRIAL RADIOGRAPHY AND RADIATION SAFETY REQUIREMENTS FOR INDUSTRIAL... physical inventory to account for all sealed sources and for devices containing depleted uranium...

  10. 10 CFR 34.29 - Quarterly inventory.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Quarterly inventory. 34.29 Section 34.29 Energy NUCLEAR REGULATORY COMMISSION LICENSES FOR INDUSTRIAL RADIOGRAPHY AND RADIATION SAFETY REQUIREMENTS FOR INDUSTRIAL... physical inventory to account for all sealed sources and for devices containing depleted uranium...

  11. 10 CFR 34.29 - Quarterly inventory.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Quarterly inventory. 34.29 Section 34.29 Energy NUCLEAR REGULATORY COMMISSION LICENSES FOR INDUSTRIAL RADIOGRAPHY AND RADIATION SAFETY REQUIREMENTS FOR INDUSTRIAL... physical inventory to account for all sealed sources and for devices containing depleted uranium...

  12. 40 CFR 52.1533 - Emission inventories.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Emission inventories. 52.1533 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New Hampshire § 52.1533 Emission inventories. (a) The Governor's designee for the State of New Hampshire submitted a 1990 base year...

  13. 40 CFR 52.1391 - Emission inventories.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Emission inventories. 52.1391 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Montana § 52.1391 Emission inventories. (a) The Governor of the State of Montana submitted the 1990 carbon monoxide base year emission...

  14. 40 CFR 52.2086 - Emission inventories.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 5 2013-07-01 2013-07-01 false Emission inventories. 52.2086 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Rhode Island § 52.2086 Emission inventories. (a) The Governor's designee for the State of Rhode Island submitted the 1990 base year...

  15. 40 CFR 52.1391 - Emission inventories.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 4 2014-07-01 2014-07-01 false Emission inventories. 52.1391 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Montana § 52.1391 Emission inventories. (a) The Governor of the State of Montana submitted the 1990 carbon monoxide base year emission...

  16. 40 CFR 52.2086 - Emission inventories.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 5 2012-07-01 2012-07-01 false Emission inventories. 52.2086 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Rhode Island § 52.2086 Emission inventories. (a) The Governor's designee for the State of Rhode Island submitted the 1990 base year...

  17. 40 CFR 52.2086 - Emission inventories.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Emission inventories. 52.2086 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Rhode Island § 52.2086 Emission inventories. (a) The Governor's designee for the State of Rhode Island submitted the 1990 base year...

  18. 40 CFR 52.1533 - Emission inventories.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 4 2012-07-01 2012-07-01 false Emission inventories. 52.1533 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New Hampshire § 52.1533 Emission inventories. (a) The Governor's designee for the State of New Hampshire submitted a 1990 base year...

  19. 40 CFR 52.1391 - Emission inventories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Emission inventories. 52.1391 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Montana § 52.1391 Emission inventories. (a) The Governor of the State of Montana submitted the 1990 carbon monoxide base year emission...

  20. 40 CFR 52.2086 - Emission inventories.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 5 2014-07-01 2014-07-01 false Emission inventories. 52.2086 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Rhode Island § 52.2086 Emission inventories. (a) The Governor's designee for the State of Rhode Island submitted the 1990 base year...

  1. 40 CFR 52.1391 - Emission inventories.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 4 2012-07-01 2012-07-01 false Emission inventories. 52.1391 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Montana § 52.1391 Emission inventories. (a) The Governor of the State of Montana submitted the 1990 carbon monoxide base year emission...

  2. 40 CFR 52.2086 - Emission inventories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Emission inventories. 52.2086 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Rhode Island § 52.2086 Emission inventories. (a) The Governor's designee for the State of Rhode Island submitted the 1990 base year...

  3. 40 CFR 52.1533 - Emission inventories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Emission inventories. 52.1533 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) New Hampshire § 52.1533 Emission inventories. (a) The Governor's designee for the State of New Hampshire submitted a 1990 base year...

  4. 40 CFR 52.1391 - Emission inventories.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 4 2013-07-01 2013-07-01 false Emission inventories. 52.1391 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Montana § 52.1391 Emission inventories. (a) The Governor of the State of Montana submitted the 1990 carbon monoxide base year emission...

  5. Validity of the Decisional Process Inventory.

    ERIC Educational Resources Information Center

    Marco, Cynthia D.; Hartung, Paul J.; Newman, Isadore; Parr, Patricia

    2003-01-01

    The Gestalt-based Decisional Process Inventory and measures of career indecision and vocational identity were completed by 201 subjects. Results supported the inventory's ability to differentiate by career choice states. Concurrent validity was supported, but confirmatory factor analysis did not support the factor structure regarding measurement…

  6. Inventory and Billing Systems for Multiple Users.

    ERIC Educational Resources Information Center

    Frazier, Lavon

    Washington State University developed a comprehensive supplies inventory system and a generalized billing system with multiple users in mind. The supplies inventory control system developed for Central Stores, a self-sustaining service center that purchases and warehouses office, laboratory, and hardware supplies, was called AIMS, An Inventory…

  7. Construct Validation of the Physics Metacognition Inventory

    ERIC Educational Resources Information Center

    Taasoobshirazi, Gita; Farley, John

    2013-01-01

    The 24-item Physics Metacognition Inventory was developed to measure physics students' metacognition for problem solving. Items were classified into eight subcomponents subsumed under two broader components: knowledge of cognition and regulation of cognition. The students' scores on the inventory were found to be reliable and related to students'…

  8. 23 CFR 650.315 - Inventory.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., STRUCTURES, AND HYDRAULICS National Bridge Inspection Standards § 650.315 Inventory. (a) Each State or... for the Structure Inventory and Appraisal of the Nation's Bridges.” (b) For routine, in-depth... after the change in status of the structure for State or Federal agency bridges and within 180...

  9. 23 CFR 650.315 - Inventory.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., STRUCTURES, AND HYDRAULICS National Bridge Inspection Standards § 650.315 Inventory. (a) Each State or... for the Structure Inventory and Appraisal of the Nation's Bridges.” (b) For routine, in-depth... after the change in status of the structure for State or Federal agency bridges and within 180...

  10. 23 CFR 650.315 - Inventory.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., STRUCTURES, AND HYDRAULICS National Bridge Inspection Standards § 650.315 Inventory. (a) Each State or... for the Structure Inventory and Appraisal of the Nation's Bridges.” (b) For routine, in-depth... after the change in status of the structure for State or Federal agency bridges and within 180...

  11. 23 CFR 650.315 - Inventory.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., STRUCTURES, AND HYDRAULICS National Bridge Inspection Standards § 650.315 Inventory. (a) Each State or... for the Structure Inventory and Appraisal of the Nation's Bridges.” (b) For routine, in-depth... after the change in status of the structure for State or Federal agency bridges and within 180...

  12. 23 CFR 650.315 - Inventory.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., STRUCTURES, AND HYDRAULICS National Bridge Inspection Standards § 650.315 Inventory. (a) Each State or... for the Structure Inventory and Appraisal of the Nation's Bridges.” (b) For routine, in-depth... after the change in status of the structure for State or Federal agency bridges and within 180...

  13. Consultant/Linker Knowledge and Skills Inventory.

    ERIC Educational Resources Information Center

    Smink, Jay

    The Consultant/Linker Knowledge and Skills Inventory is used to assess both existing and needed levels of knowledge and skills for consulting with school staff. The inventory is self-administered, and requires 20 to 30 minutes to complete. For each item, knowledge and skill are rated low, medium, or high; and need for improvement is rated none,…

  14. The Padua Inventory: Do Revisions Need Revision?

    ERIC Educational Resources Information Center

    Gonner, Sascha; Ecker, Willi; Leonhart, Rainer

    2010-01-01

    The purpose of the present study was to examine the psychometric properties, factorial structure, and validity of the Padua Inventory-Washington State University Revision and of the Padua Inventory-Revised in a large sample of patients with obsessive-compulsive disorder (n = 228) and with anxiety disorders and/or depression (n = 213). The…

  15. Achieve inventory reduction and improve customer service?

    PubMed

    Moody, M C

    2000-05-01

    Is it really possible to achieve significant reductions in your manufacturing inventories while improving customer service? If you really want to achieve significant inventory reductions, focus on the root causes, and develop countermeasures and a work plan, to execute your countermeasures. Include measurements for recording your progress, and deploy your countermeasures until they are no longer required, or until new ones are needed.

  16. 48 CFR 3045.508 - Physical inventories.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Physical inventories. 3045.508 Section 3045.508 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND... Property in the Possession of Contractors 3045.508 Physical inventories....

  17. Relativity Concept Inventory: Development, Analysis, and Results

    ERIC Educational Resources Information Center

    Aslanides, J. S.; Savage, C. M.

    2013-01-01

    We report on a concept inventory for special relativity: the development process, data analysis methods, and results from an introductory relativity class. The Relativity Concept Inventory tests understanding of relativistic concepts. An unusual feature is confidence testing for each question. This can provide additional information; for example,…

  18. Purdue Elementary Problem-Solving Inventory.

    ERIC Educational Resources Information Center

    Purdue Univ., Lafayette, IN. Educational Research Center.

    This inventory was designed to assess the general problem solving ability of disadvantaged elementary school children from various ethnic backgrounds and grade levels. Twelve tasks are included in the inventory: sensing the problem, identifying the problem, asking questions, guessing causes, clarification of goals, judging if more information is…

  19. 27 CFR 25.294 - Inventories.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... physical inventory of beer and cereal beverage at least once each calendar month. The brewer may take this... record of inventories of beer or cereal beverage which will show the following: (1) Date taken; (2) Quantity of beer and cereal beverage on hand; (3) Losses, gains, and shortages; and (4) Signature,...

  20. 27 CFR 25.294 - Inventories.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... physical inventory of beer and cereal beverage at least once each calendar month. The brewer may take this... record of inventories of beer or cereal beverage which will show the following: (1) Date taken; (2) Quantity of beer and cereal beverage on hand; (3) Losses, gains, and shortages; and (4) Signature,...

  1. 27 CFR 25.294 - Inventories.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... physical inventory of beer and cereal beverage at least once each calendar month. The brewer may take this... record of inventories of beer or cereal beverage which will show the following: (1) Date taken; (2) Quantity of beer and cereal beverage on hand; (3) Losses, gains, and shortages; and (4) Signature,...

  2. 21 CFR 1315.24 - Inventory allowance.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Inventory allowance. 1315.24 Section 1315.24 Food... EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Individual Manufacturing Quotas § 1315.24 Inventory... registered manufacturer shall be allowed as a part of the quota an amount sufficient to maintain an...

  3. 48 CFR 3045.508 - Physical inventories.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Physical inventories. 3045.508 Section 3045.508 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND... Property in the Possession of Contractors 3045.508 Physical inventories....

  4. 21 CFR 1315.24 - Inventory allowance.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Inventory allowance. 1315.24 Section 1315.24 Food... EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLPROPANOLAMINE Individual Manufacturing Quotas § 1315.24 Inventory... registered manufacturer shall be allowed as a part of the quota an amount sufficient to maintain an...

  5. Postsecondary Education Facilities Inventory and Classification Manual.

    ERIC Educational Resources Information Center

    Korb, Roslyn

    This publication is intended to supersede the Higher Education and Facilities Inventory and Classification Manual (FICM) first published in December 1972. Like the earlier manual, this revised and updated version provides a common framework and coding structure to be used in collecting and reporting inventory data on college and university…

  6. 47 CFR 32.1220 - Inventories.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Inventories. 32.1220 Section 32.1220 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES UNIFORM SYSTEM OF ACCOUNTS FOR TELECOMMUNICATIONS COMPANIES Instructions for Balance Sheet Accounts § 32.1220 Inventories....

  7. The Automation Inventory of Research Libraries, 1989.

    ERIC Educational Resources Information Center

    Fayen, Emily Gallup

    This inventory provides profiles, tables, and listings describing automated library activities at 103 Association of Research Libraries (ARL) institutions. The inventory includes analyses of aggregate information from individual library profiles which are then divided into three categories that reflect primarily bibliographic functions: (1)…

  8. 27 CFR 25.294 - Inventories.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... physical inventory of beer and cereal beverage at least once each calendar month. The brewer may take this... record of inventories of beer or cereal beverage which will show the following: (1) Date taken; (2) Quantity of beer and cereal beverage on hand; (3) Losses, gains, and shortages; and (4) Signature,...

  9. 27 CFR 25.294 - Inventories.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... physical inventory of beer and cereal beverage at least once each calender month. The brewer may take this... record of inventories of beer or cereal beverage which will show the following: (1) Date taken; (2) Quantity of beer and cereal beverage on hand; (3) Losses, gains, and shortages; and (4) Signature,...

  10. Inventory Data Package for Hanford Assessments

    SciTech Connect

    Kincaid, Charles T.; Eslinger, Paul W.; Aaberg, Rosanne L.; Miley, Terri B.; Nelson, Iral C.; Strenge, Dennis L.; Evans, John C.

    2006-06-01

    This document presents the basis for a compilation of inventory for radioactive contaminants of interest by year for all potentially impactive waste sites on the Hanford Site for which inventory data exist in records or could be reasonably estimated. This document also includes discussions of the historical, current, and reasonably foreseeable (1944 to 2070) future radioactive waste and waste sites; the inventories of radionuclides that may have a potential for environmental impacts; a description of the method(s) for estimating inventories where records are inadequate; a description of the screening method(s) used to select those sites and contaminants that might make a substantial contribution to impacts; a listing of the remedial actions and their completion dates for waste sites; and tables showing the best estimate inventories available for Hanford assessments.

  11. 78 FR 47273 - Information Collection; Inventory Property Management

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-05

    ... Farm Service Agency Information Collection; Inventory Property Management AGENCY: Farm Service Agency... Inventory Property Management. The information is used to evaluate applicant requests to purchase inventory... Desk Officer for Agriculture, Office of Information and Regulatory Affairs, Office of Management...

  12. Use of microcomputers for inventory management with uncertain demand

    SciTech Connect

    Meadows, B F

    1984-01-01

    This paper describes how a microcomputer is used for analysis of inventory trends to optimize inventory investment and customer service level in a distribution environment with uncertain demand, and to support an inventory subsystem resident on a main computer.

  13. 48 CFR 645.608 - Screening of contractor inventory.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... inventory. 645.608 Section 645.608 Federal Acquisition Regulations System DEPARTMENT OF STATE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Redistribution, and Disposal of Contractor Inventory 645.608 Screening of contractor inventory....

  14. 48 CFR 645.608 - Screening of contractor inventory.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... inventory. 645.608 Section 645.608 Federal Acquisition Regulations System DEPARTMENT OF STATE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Reporting, Redistribution, and Disposal of Contractor Inventory 645.608 Screening of contractor inventory....

  15. Smear layer removal efficacy of combination of herbal extracts in two different ratios either alone or supplemented with sonic agitation: An in vitro scanning electron microscope study

    PubMed Central

    Chhabra, Naveen; Gyanani, Hitesh; Kamatagi, Laxmikant

    2015-01-01

    Objectives: The study aimed to evaluate the effectiveness of the combination of two natural extracts in varying ratios for removal of smear layer either alone or supplemented with sonic agitation. Materials and Methods: Fifty extracted single-rooted teeth were collected, disinfected and decoronated below the cementoenamel junction to obtain standardized root length of 10 mm. Root canals were instrumented using rotary files at working length 1 mm short of the apex. Specimens were divided into six groups according to the irrigation protocol as follows: Group A – Distilled water, Group B – 17% ethylenediaminetetraacetic acid, Group C – Herbal extracts in 1:1 ratio, Group D – Herbal extracts in 1:1 ratio supplemented with sonic agitation, Group E – Herbal extracts in 2:1 ratio, Group F – Herbal extracts in 2:1 ratio supplemented with sonic agitation. Specimens were longitudinally sectioned and evaluated under scanning electron microscope for smear layer removal efficacy. Obtained scores were statistically analyzed using one-way analysis of variance and post-hoc test. Results: Among all, Group B showed the best results followed by Group F. Remaining other groups showed inferior outcome (P < 0.05). Conclusion: The combination of two extracts in 2:1 ratio was slightly better than 1:1 ratio and the smear layer removal efficacy was further improved when accompanied with sonic agitation. PMID:26430300

  16. Effects of heat, pH, antioxidant, agitation and light on betacyanin stability using red-fleshed dragon fruit (Hylocereus polyrhizus) juice and concentrate as models.

    PubMed

    Wong, Yen-Ming; Siow, Lee-Fong

    2015-05-01

    Red-fleshed dragon fruit (Hylocereus polyrhizus) is rich in antioxidants. The aim of this study was to determine the effects of heat pasteurization, pH adjustment, ascorbic acid addition as well as storage under agitation and light or dark condition on betacyanin content in red-fleshed dragon fruit (Hylocereus polyrhizus) juice and concentrate. The concentrate was produced by concentrating clarified red-fleshed dragon fruit juice in a rotary evaporator at 40 °C. UV-Visible spectrophotometer was used for analyzing betacyanin content. Addition of 0.25 % ascorbic acid, pH 4.0, and pasteurization at 65 °C for 30 min were selected as the best processing conditions to retain betacyanin content in red-fleshed dragon fruit juice. Storage at the agitation speed of 220 rpm showed that the concentrated samples had higher betacyanin stability compared to juice, while both juice and concentrate had almost similar betacyanin stability when tested for storage in the presence of light. In summary, ascorbic acid stabilized betacyanin in both juice and concentrate at agitated or non-agitated conditions. In contrast, light degraded betacyanin in both juice and concentrate models.

  17. Rages or Temper Tantrums? The Behavioral Organization, Temporal Characteristics, and Clinical Significance of Angry-Agitated Outbursts in Child Psychiatry Inpatients

    ERIC Educational Resources Information Center

    Potegal, Michael; Carlson, Gabrielle; Margulies, David; Gutkovitch, Zinoviy; Wall, Melanie

    2009-01-01

    Angry, agitated outbursts (AAOs) are a common precipitant of children's psychiatric hospitalization. In the hospital, AAOs present both management and diagnostic challenges, e.g., while they have recently been described as manic "rages", older studies suggest that they may be exacerbated temper tantrums. Factor analyses of 109 AAOs had by 46…

  18. Influence of milk pretreatment on production of free fatty acids and volatile compounds in hard cheeses: heat treatment and mechanical agitation.

    PubMed

    Vélez, M A; Perotti, M C; Wolf, I V; Hynes, E R; Zalazar, C A

    2010-10-01

    This work aimed to identify technological steps that can increase fat hydrolysis and volatile compounds production in hard cheeses; these biochemical events have been related with improved piquant taste and development of genuine flavor during cheese ripening. For that purpose, 2 different pretreatments of cheese milk were tested: heat treatment and mechanical agitation. Both factors were assayed at 2 levels: milk was either batch pasteurized or nonthermally treated, and mechanical agitation was either applied or not applied. For all combinations, hard cheeses (Reggianito type) were produced in a pilot plant and ripened for 90 d. In all cheeses the degree of lipolysis, assessed by gas chromatography, increased similarly during ripening. However, the proportion of short-chain fatty acids was higher in the cheeses made with unpasteurized milk, suggesting a higher activity of lipases with positional specificity toward the sn-3 position of the triglyceride, among which milk lipoprotein lipase is found. Similar results were found for most of the volatile compounds, determined by solid-phase microextraction-gas chromatography flame-ionization detector/mass spectrometry, which constitute the groups of ketones, alcohols, esters, and the group of acids. On the contrary, no effect of mechanical agitation was observed, although some interactions between factors were found. In the conditions of the study, results suggest that heat treatment had a higher effect on cheese lipolysis and volatile compounds production than partial destabilization of the fat emulsion produced by the agitation method applied.

  19. Impact of aeration and agitation on metabolic heat and protease secretion of Aspergillus tamarii in a real-time biological reaction calorimeter.

    PubMed

    Dhandapani, Balaji; Mahadevan, Surianarayanan; Dhilipkumar, Sathish Sundar; Rajkumar, Suseela; Mandal, Asit Baran

    2012-06-01

    The effects of aeration and agitation on metabolic heat, alkaline protease production and morphology for Aspergillus tamarii MTCC5152 are reported in this manuscript. Measurement of metabolic heat has been attempted by the continuous and dynamic heat balance method in a biological real-time reaction calorimeter. At lower agitation intensities, growth-related processes were dominating. As a result the protease activity and the product heat yields were lower than those for 350 and 450 rpm. Although biomass growth was necessary to obtain maximum protease yield, agitation seemed to play a vital role in the protease production process. Energy dissipation per circulation function of the process is also deduced from power input. At optimal conditions, 350 rpm and 1 vvm, the gassed power required was 0.133 W. Pellet morphology and protease production were studied under different aeration and agitation intensities of A. tamarii. Pellet structure was considerably influenced by DO, a higher DO level resulted in denser pellets (1,018.4 kg/m(3)) leading to higher protease activity. Coupling of hydrodynamics and bio-reaction highlighted the complex relationship between energy dissipation, substrate uptake rate and fungal physiology. This study emphasised the potential of biocalorimetry as a reliable monitoring and robust control tool for aerobic fermentation of A. tamarii, using agricultural by-products.

  20. The effect of magnesium sulphate infusion on the incidence and severity of emergence agitation in children undergoing adenotonsillectomy using sevoflurane anaesthesia.

    PubMed

    Abdulatif, M; Ahmed, A; Mukhtar, A; Badawy, S

    2013-10-01

    This randomised, controlled, double-blind study investigated the effects of intra-operative magnesium sulphate administration on the incidence of emergence agitation in children undergoing adenotonsillectomy using sevoflurane anaesthesia. Seventy children were randomly allocated to receive a 30 mg.kg(-1) bolus of intravenous magnesium sulphate after induction of anaesthesia followed by a continuous infusion of 10 mg.kg(-1).h(-1) or an equal volume of saline 0.9%. All children received titrated sevoflurane anaesthesia adjusted to maintain haemodynamic stability. The Pediatric Anesthesia Emergence Delirium scale and the Children's Hospital of Eastern Ontario Score were used for the assessment of postoperative emergence agitation and pain, respectively. Emergence agitation was more common in the control group than in the magnesium group (23 (72%) and 12 (36%), respectively (p = 0.004)), with a relative risk of 0.51 (95% CI 0.31-0.84), an absolute risk reduction of 0.35 (95% CI 0.10-0.54), and number needed to treat of 3 (95% CI 2-9). Postoperative pain scores were comparable in the two groups. Magnesium sulphate reduces the incidence and severity of emergence agitation in children undergoing adenotonsillectomy using sevoflurane anaesthesia and is not associated with increased postoperative side-effects or delayed recovery.

  1. Comparison of calcium hydroxide removal by self-adjusting file, EndoVac, and CanalBrush agitation techniques: An in vitro study

    PubMed Central

    Türker, Sevinç Aktemur; Koçak, Mustafa Murat; Koçak, Sibel; Sağlam, Baran Can

    2013-01-01

    Objectives: This study comparatively evaluated the efficacy of self-adjusting file (SAF), Endovac, and CanalBrush irrigant agitation protocols in removing calcium hydroxide (Ca(OH)2) from the root canals. Materials and Methods: Sixty extracted human mandibular canine teeth were instrumented with ProTaper rotary instruments to size #40 and dressed with Ca(OH)2. The roots were randomly assigned to four groups according to irrigant agitation protocol used (n = 15). In Group 1: Conventional syringe irrigation (no activation, control); Group 2: Rotary brush agitation (CanalBrush); Group 3: Apical negative pressure irrigation (EndoVac system); and Group 4: Sonic agitation (SAF) were used. Scanning electron microscopic (SEM) evaluation was done for assessment of Ca(OH)2 removal in the coronal and apical thirds. Statistical analysis was performed by Wilcoxon and Kruskal-Wallis tests. Results: There were statistically significant differences among the groups (P = 0.218). A statistically significant difference was seen between the test groups in Ca(OH)2 removal from the apical third of the canal (P < 0.05). In the coronal third, there was no difference between the groups (P > 0.05). The most efficient Ca(OH)2 removal in apical third was recorded in Group 3 (EndoVac) and Group 4 (SAF) (P < 0.05). In Group 4 (sonic agitation), there was no significantly difference between Ca(OH)2 removal in coronal and apical thirds. Conclusions: SAF and EndoVac showed significantly better performance than CanalBrush and conventional syringe irrigation in removing Ca(OH)2 from apical third of the root canals. PMID:24082574

  2. Effect of impeller type and agitation on the performance of pilot scale ASBR and AnSBBR applied to sanitary wastewater treatment.

    PubMed

    de Novaes, Luciano Farias; Saratt, Bruna Luckmann; Rodrigues, José Alberto Domingues; Ratusznei, Suzana Maria; de Moraes, Deovaldo; Ribeiro, Rogers; Zaiat, Marcelo; Foresti, Eugenio

    2010-08-01

    The objective of this work was to assess the effect of agitation rate and impeller type in two mechanically stirred sequencing batch reactors: one containing granulated biomass (denominated ASBR) and the other immobilized biomass on polyurethane foam (denominated AnSBBR). Each configuration, with total volume of 1 m(3), treated 0.65 m(3) sanitary wastewater at ambient temperature in 8-h cycles. Three impeller types were assessed for each reactor configuration: flat-blade turbine impeller, 45 degrees -inclined-blade turbine impeller and helix impeller, as well as two agitation rates: 40 and 80 rpm, resulting in a combination of six experimental conditions. In addition, the ASBR was also operated at 20 rpm with a flat-blade turbine impeller and the AnSBBR was operated with a draft tube and helix impeller at 80 and 120 rpm. To quantify how impeller type and agitation rate relate to substrate consumption rate, results obtained during monitoring at the end of the cycle, as well as the time profiles during a cycle were analyzed. Increasing agitation rate from 40 rpm to 80 rpm in the AnSBBR improved substrate consumption rate whereas in the ASBR this increase destabilized the system, likely due to granule rupture caused by the higher agitation. The AnSBBR showed highest solids and substrate removal, highest kinetic constant and highest alkalinity production when using a helix impeller, 80 rpm, and no draft tube. The best condition for the ASBR was achieved with a flat-blade turbine impeller at 20 rpm. The presence of the draft tube in the AnSBBR did not show significant improvement in reactor efficiency. Furthermore, power consumption studies in these pilot scale reactors showed that power transfer required to improve mass transfer might be technically and economically feasible.

  3. How to conduct an emissions inventory

    SciTech Connect

    Topazio, R.J.

    1994-07-01

    An inventory will quantify emissions through source identification, extensive data gathering, research, process investigation, emission rate calculation and control equipment efficiency determination. For most facilities, a proper inventory will take six months to complete. Add that to the time it will take to prepare the permit application and it becomes evident that action needs to be taken now. Deadlines for submitting Title V operating permit applications to state agencies are right around the corner. This paper describes the process of conducting an emissions inventory.

  4. SCIS. Small Container Storage Inventory System

    SciTech Connect

    Esworthy, S.

    1988-09-01

    SCIS, the Small Container Inventory System, was developed to track the chemical inventory in the Small Container Storage Facility. Running totals of the amounts of stored chemicals can be extracted daily, with reports generated at the close of business on the last working day of each month. SCIS is designed to provide complete logging of all chemical transactions of the Facility. Records can be retrieved based on key information in any of the 14 fields in the system. Eight reports are available by division, cabinet number, and chemical name; for chemicals removed and chemicals remaining; for all transactions occurring during a specified month; and a current inventory by chemical name and cabinet number.

  5. Relativity concept inventory: Development, analysis, and results

    NASA Astrophysics Data System (ADS)

    Aslanides, J. S.; Savage, C. M.

    2013-06-01

    We report on a concept inventory for special relativity: the development process, data analysis methods, and results from an introductory relativity class. The Relativity Concept Inventory tests understanding of relativistic concepts. An unusual feature is confidence testing for each question. This can provide additional information; for example, high confidence correlated with incorrect answers suggests a misconception. A novel aspect of our data analysis is the use of Monte Carlo simulations to determine the significance of correlations. This approach is particularly useful for small sample sizes, such as ours. Our results show a gender bias that was not present in course assessment, similar to that reported for the Force Concept Inventory.

  6. Inventory of state energy models

    SciTech Connect

    Melcher, A.G.; Gist, R.L.; Underwood, R.G.; Weber, J.C.

    1980-03-31

    These models address a variety of purposes, such as supply or demand of energy or of certain types of energy, emergency management of energy, conservation in end uses of energy, and economic factors. Fifty-one models are briefly described as to: purpose; energy system; applications;status; validation; outputs by sector, energy type, economic and physical units, geographic area, and time frame; structure and modeling techniques; submodels; working assumptions; inputs; data sources; related models; costs; references; and contacts. Discussions in the report include: project purposes and methods of research, state energy modeling in general, model types and terminology, and Federal legislation to which state modeling is relevant. Also, a state-by-state listing of modeling efforts is provided and other model inventories are identified. The report includes a brief encylopedia of terms used in energy models. It is assumed that many readers of the report will not be experienced in the technical aspects of modeling. The project was accomplished by telephone conversations and document review by a team from the Colorado School of Mines Research Institute and the faculty of the Colorado School of Mines. A Technical Committee (listed in the report) provided advice during the course of the project.

  7. National Coal Quality Inventory (NACQI)

    SciTech Connect

    Robert Finkelman

    2005-09-30

    The U.S. Geological Survey (USGS) conducted the National Coal Quality Inventory (NaCQI) between 1999 and 2005 to address a need for quality information on coals that will be mined during the next 20-30 years. Collaboration between the USGS, State geological surveys, universities, coal burning utilities, and the coal mining industry plus funding support from the Electric Power Research Institute (EPRI) and the U.S. Department of Energy (DOE) permitted collection and submittal of coal samples for analysis. The chemical data (proximate and ultimate analyses; major, minor and trace element concentrations) for 729 samples of raw or prepared coal, coal associated shale, and coal combustion products (fly ash, hopper ash, bottom ash and gypsum) from nine coal producing States are included. In addition, the project identified a new coal reference analytical standard, to be designated CWE-1 (West Elk Mine, Gunnison County, Colorado) that is a high-volatile-B or high-volatile-A bituminous coal with low contents of ash yield and sulfur, and very low, but detectable contents of chlorine, mercury and other trace elements.

  8. Automatic water inventory, collecting, and dispensing unit

    NASA Technical Reports Server (NTRS)

    Hall, J. B., Jr.; Williams, E. F.

    1972-01-01

    Two cylindrical tanks with piston bladders and associated components for automatic filling and emptying use liquid inventory readout devices in control of water flow. Unit provides for adaptive water collection, storage, and dispensation in weightlessness environment.

  9. 47 CFR 32.1220 - Inventories.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... FOR TELECOMMUNICATIONS COMPANIES Instructions for Balance Sheet Accounts § 32.1220 Inventories. (a... retirement units shall be included in this account at current prices new. (3) The cost of repairing...

  10. 47 CFR 32.1220 - Inventories.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... FOR TELECOMMUNICATIONS COMPANIES Instructions for Balance Sheet Accounts § 32.1220 Inventories. (a... retirement units shall be included in this account at current prices new. (3) The cost of repairing...

  11. 47 CFR 32.1220 - Inventories.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... FOR TELECOMMUNICATIONS COMPANIES Instructions for Balance Sheet Accounts § 32.1220 Inventories. (a... retirement units shall be included in this account at current prices new. (3) The cost of repairing...

  12. NASA's Education Program Inventory FY 91

    NASA Technical Reports Server (NTRS)

    1992-01-01

    In 1988, the Education Division produced an inventory of NASA-supported education programs. Since then, mathematics, science, and technology education has taken on a more visible role, not only as part of NASA's mission, but as part of the National Education Goals and other Federal initiatives. Therefore, it became important to update the 1988 inventory in order to achieve a more accurate and comprehensive look at NASA's educational programs. The data collected is summarized and descriptions of each program are provided.

  13. How to leverage a bad inventory situation.

    PubMed

    Horsfall, G A

    1998-11-01

    Small manufacturing companies have a hard time taking advantage of the price breaks that result from large purchase orders. Besides the greater amount of money involved, purchasing large quantities of items demands additional space for storing the items. This article describes a company that created separate inventory management and finance company to provide inventory management services to itself and to market these services to other small companies in its area.

  14. Impact of vibration and agitation speed on dissolution of USP prednisone tablets RS and various IR tablet formulations.

    PubMed

    Seeger, Nicole; Lange, Sigrid; Klein, Sandra

    2015-08-01

    Dissolution testing is an in vitro procedure which is widely used in quality control (QC) of solid oral dosage forms and, given that real biorelevant test conditions are applied, can also be used as a predictive tool for the in vivo performance of such formulations. However, if a dissolution method is intended to be used for such purposes, it has to deliver results that are only determined by the quality of the test product, but not by other variables. In the recent past, more and more questions were arising on how to address the effects of vibration on dissolution test results. The present study was performed to screen for the correlation of prednisone dissolution of USP Prednisone Tablets RS with vibration caused by a commercially available vibration source as well as to investigate how drug release from a range of immediate release formulations containing class 1-4 drugs of the biopharmaceutical classification scheme is affected by vibration when performing dissolution experiments at different agitation rates. Results of the present study show that the dissolution process of oral drug formulations can be affected by vibration. However, it also becomes clear that the degree of which a certain level of vibration impacts dissolution is strongly dependent on several factors such as drug properties, formulation parameters, and the design of the dissolution method. To ensure the establishment of robust and predictive dissolution test methods, the impact of variation should thus be considered in method design and validation.

  15. Mushroom polysaccharides and lipids synthesized in liquid agitated and static cultures. Part I: screening various mushroom species.

    PubMed

    Diamantopoulou, Panagiota; Papanikolaou, Seraphim; Kapoti, Maria; Komaitis, Michael; Aggelis, George; Philippoussis, Antonios

    2012-06-01

    The effect of four synthetic media containing glucose (initial concentration 30 g l(-1)) on mycelial growth, exopolysaccharides (EPS) and cellular lipids production was examined in 11 mushroom species after 12 and 16 days of culture in static- and shake-flasks. Fatty acid analysis of cellular lipids produced was also performed. Agitation had a positive effect on biomass production, glucose consumption and lipid biosynthesis. Media that favoured the production of biomass were not suitable for EPS biosynthesis and vice versa. Biomass values varied from ~1.0 g l(-1) (Lentinula edodes) to ~19 g l(-1) (Pleurotus ostreatus), while the highest EPS quantity achieved ranged between 1.6 and 1.8 g l(-1) (for Ganoderma lucidum and L. edodes, respectively). Quantities of total cellular lipids varied between 2.5 and 18.5 % w/w, in dry mycelial mass for the fungi tested. Lipid in dry weight values were influenced by the medium composition. Cellular lipids presented noticeable quantities of poly-unsaturated fatty acids like linoleic acid. Compared to most of the mushrooms tested, lipids of Volvariella volvacea were more saturated. The ability of several mushroom species of our study to produce in notable quantities the above-mentioned added-value compounds renders these fungi worthy for further investigations.

  16. Storage of platelets on flatbed agitators in polyvinyl chloride blood bags plasticized with tri(2-ethylhexyl) trimellitate.

    PubMed

    Champion, A B; Chong, C; Carmen, R A

    1987-01-01

    Data are presented showing that platelets in polyvinyl chloride blood bags plasticized with tri(2-ethylhexyl) trimellitate can be stored on flatbed agitators (shakers) without the pH falling below 6.0. The lowest pH seen after 7 days of storage in 46 units with platelet yields ranging from 3.6 to 13.3 X 10(10) per unit was 6.43. These bags have a O2 transmission rate of 13.3 mumol per hour per bag. Platelet bags with a O2 transmission rate of 7.9 mumol per hour per bag experience a pH fall after 5 days of storage on the shaker in units whose platelet yield on average exceeds 10 X 10(10). Platelets can be stored on first-generation shakers (70 cycles/min, stroke = 1 inch) without an attempt at manual resuspension of the platelet button. The count after 30 minutes on the shaker averaged 89 +/- 15 percent of the expected count, indicating that resuspension was nearly complete after a relatively short period. Red cells, but not platelets, settled out during storage on the shaker.

  17. An efficient approach for phosphorus recovery from wastewater using series-coupled air-agitated crystallization reactors.

    PubMed

    Dai, Hongliang; Lu, Xiwu; Peng, Yonghong; Zou, Haiming; Shi, Jing

    2016-12-01

    Homogeneous nucleation of hydroxyapatite (HAP) crystallization in high levels of supersaturation solution has a negative effect on phosphorus recovery efficiency because of the poor settleability of the generated HAP microcrystalline. In this study, a new high-performance approach for phosphorus recovery from anaerobic supernatant using three series-coupled air-agitated crystallization reactors was developed and characterized. During 30-day operation, the proposed process showed a high recovery efficiency (∼95.82%) and low microcrystalline ratio (∼3.11%). Particle size analysis showed that the microcrystalline size was successively increased (from 5.81 to 26.32 μm) with the sequence of series-coupled reactors, confirming the conjectural mechanism that a multistage-induced crystallization system provided an appropriate condition for the growth, aggregation, and precipitation of crystallized products. Furthermore, the new process showed a broad spectrum of handling ability for different concentrations of phosphorus-containing solution in the range of 5-350 mg L(-1), and the obtained results of phosphorus conversion ratio and recovery efficiency were more than 92% and 80%, respectively. Overall, these results showed that the new process exhibited an excellent ability of efficient phosphorus recovery as well as wide application scope, and might be used as an effective approach for phosphorus removal and recovery from wastewater.

  18. Smoking-Related Correlates of Psychomotor Restlessness and Agitation in a Community Sample of Daily Cigarette Smokers

    PubMed Central

    Wong, Jordan A.; Leventhal, Adam M.

    2015-01-01

    Background and Objectives Psychomotor restlessness and agitation (PMA) is a putatively important, yet understudied, psychopathologic correlate of smoking. The scant smoking research on PMA previously conducted has been narrow in scope and conducted among psychiatric patients. To examine the generalizability and relevance of PMA to smoking, this cross-sectional study investigated associations between PMA and a variety of smoking processes in a community sample. Methods Participants in this study were non-treatment-seeking smokers (N = 254, ≥10 cig/day, M age = 44 years) from the community without an active mood disorder. At baseline, they completed a PMA symptom checklist, a composite depressive symptom index, and a battery of smoking questionnaires. Results Linear regression models adjusting for depressive symptoms and demographics indicated that PMA level was positively associated with severity of nicotine withdrawal symptoms during prior quit attempts (β = .18, p < .05), anticipated likelihood of withdrawal in a future quit attempt (β = .19, p < .05), motivation to smoke for negative reinforcement (β = .14, p < .05), and smoking expectancies for negative reinforcement (β = .17, p < .05), negative consequences (β = .22, p < .01), and positive reinforcement (β = .14, p < .05). PMA was not significantly associated with smoking chronicity, frequency, or dependence severity. Conclusion and Scientific Significance Smokers with elevated PMA appear to experience greater smoking-induced affect modulation and nicotine withdrawal than the average smoker, regardless of other depressive symptoms. Given that PMA differentiates a qualitatively unique profile of smoking characteristics, PMA warrants consideration in tobacco addiction research and practice. PMID:25864606

  19. Technical Basis for PNNL Beryllium Inventory

    SciTech Connect

    Johnson, Michelle Lynn

    2014-07-09

    The Department of Energy (DOE) issued Title 10 of the Code of Federal Regulations Part 850, “Chronic Beryllium Disease Prevention Program” (the Beryllium Rule) in 1999 and required full compliance by no later than January 7, 2002. The Beryllium Rule requires the development of a baseline beryllium inventory of the locations of beryllium operations and other locations of potential beryllium contamination at DOE facilities. The baseline beryllium inventory is also required to identify workers exposed or potentially exposed to beryllium at those locations. Prior to DOE issuing 10 CFR 850, Pacific Northwest Nuclear Laboratory (PNNL) had documented the beryllium characterization and worker exposure potential for multiple facilities in compliance with DOE’s 1997 Notice 440.1, “Interim Chronic Beryllium Disease.” After DOE’s issuance of 10 CFR 850, PNNL developed an implementation plan to be compliant by 2002. In 2014, an internal self-assessment (ITS #E-00748) of PNNL’s Chronic Beryllium Disease Prevention Program (CBDPP) identified several deficiencies. One deficiency is that the technical basis for establishing the baseline beryllium inventory when the Beryllium Rule was implemented was either not documented or not retrievable. In addition, the beryllium inventory itself had not been adequately documented and maintained since PNNL established its own CBDPP, separate from Hanford Site’s program. This document reconstructs PNNL’s baseline beryllium inventory as it would have existed when it achieved compliance with the Beryllium Rule in 2001 and provides the technical basis for the baseline beryllium inventory.

  20. Wildlife Inventory, Craig Mountain, Idaho.

    SciTech Connect

    Cassirer, E. Frances

    1995-06-01

    Wildlife distribution/abundance were studied at this location during 1993 and 1994 to establish the baseline as part of the wildlife mitigation agreement for construction of Dworshak reservoir. Inventory efforts were designed to (1) document distribution/abundance of 4 target species: pileated woodpecker, yellow warbler, black-capped chickadee, and river otter, (2) determine distribution/abundance of rare animals, and (3) determine presence and relative abundance of all other species except deer and elk. 201 wildlife species were observed during the survey period; most were residents or used the area seasonally for breeding or wintering. New distribution or breeding records were established for at least 6 species. Pileated woodpeckers were found at 35% of 134 survey points in upland forests; estimated densities were 0-0.08 birds/ha, averaging 0.02 birds/ha. Yellow warblers were found in riparian areas and shrubby draws below 3500 ft elev., and were most abundant in white alder plant communities (ave. est. densities 0.2-2. 1 birds/ha). Black-capped chickadees were found in riparian and mixed tall shrub vegetation at all elevations (ave. est. densities 0-0.7 birds/ha). River otters and suitable otter denning and foraging habitat were observed along the Snake and Salmon rivers. 15 special status animals (threatened, endangered, sensitive, state species of special concern) were observed at Craig Mt: 3 amphibians, 1 reptile, 8 birds, 3 mammals. Another 5 special status species potentially occur (not documented). Ecosystem-based wildlife management issues are identified. A monitoring plant is presented for assessing effects of mitigation activities.

  1. 25 CFR 170.442 - What is the IRR Inventory?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What is the IRR Inventory? 170.442 Section 170.442... PROGRAM Planning, Design, and Construction of Indian Reservation Roads Program Facilities Irr Inventory § 170.442 What is the IRR Inventory? (a) The IRR Inventory is a comprehensive database of...

  2. 25 CFR 170.442 - What is the IRR Inventory?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What is the IRR Inventory? 170.442 Section 170.442... PROGRAM Planning, Design, and Construction of Indian Reservation Roads Program Facilities Irr Inventory § 170.442 What is the IRR Inventory? (a) The IRR Inventory is a comprehensive database of...

  3. 26 CFR 1.471-8 - Inventories of retail merchants.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 6 2010-04-01 2010-04-01 false Inventories of retail merchants. 1.471-8 Section... (CONTINUED) INCOME TAXES Inventories § 1.471-8 Inventories of retail merchants. (a) Retail merchants who employ what is known as the “retail method” of pricing inventories may make their returns upon...

  4. 27 CFR 46.203 - Record (book) inventory requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2013-04-01 2013-04-01 false Record (book) inventory... Cigarette Tubes Held for Sale on April 1, 2009 Inventories § 46.203 Record (book) inventory requirements. (a) The dealer may use a record (book) inventory if the dealer has source records that show: (1)...

  5. 27 CFR 46.203 - Record (book) inventory requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2011-04-01 2011-04-01 false Record (book) inventory... Cigarette Tubes Held for Sale on April 1, 2009 Inventories § 46.203 Record (book) inventory requirements. (a) The dealer may use a record (book) inventory if the dealer has source records that show: (1)...

  6. 27 CFR 46.203 - Record (book) inventory requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2014-04-01 2014-04-01 false Record (book) inventory... Cigarette Tubes Held for Sale on April 1, 2009 Inventories § 46.203 Record (book) inventory requirements. (a) The dealer may use a record (book) inventory if the dealer has source records that show: (1)...

  7. 7 CFR 767.101 - Leasing real estate inventory property.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Leasing real estate inventory property. 767.101..., DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS INVENTORY PROPERTY MANAGEMENT Lease of Real Estate Inventory Property § 767.101 Leasing real estate inventory property. (a) The Agency may lease real estate...

  8. 77 FR 8818 - Publication of FY 2011 Service Contract Inventory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-15

    ... PROTECTION Publication of FY 2011 Service Contract Inventory AGENCY: Bureau of Consumer Financial Protection. ACTION: Notice of public availability of FY 2011 Service Contract Inventory. SUMMARY: In accordance with... of the FY 2011 service contract inventory. This inventory provides information on service...

  9. 7 CFR 1435.401 - CCC sugar inventory disposition.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false CCC sugar inventory disposition. 1435.401 Section... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Disposition of CCC Inventory § 1435.401 CCC sugar inventory disposition. (a) CCC will dispose of inventory in the...

  10. System to maximize inventory performance in a small hospital.

    PubMed

    VanDerLinde, L P

    1983-01-01

    A computerized system to maximize inventory performance in a small hospital is described. An inventory control system, which integrates economic order quantity (EOQ) and ABC inventory models was implemented in a 146-bed hospital. The perpetual inventory control data base, supported by the hospital's mainframe computer, generates monthly inventory statistics that are segregated into A, B, and C reports. Using a hand-held computer that interfaces with the perpetual inventory system, a series of inventory management reports were developed. These reports, which are based on the EOQ model, provide the following information for each drug line item: EOQ, EOQ proposed carrying cost, actual inventory carrying costs, safety stock, order point, average inventory, and the "on hand/on order" point. Several supplemental inventory management reports were also developed. While implementing the computerized inventory system, the pharmacy also changed its purchasing strategy from predominantly direct accounts to a progressive prime-vendor wholesaler. From December 1980 to December 1981, the ABC/EOQ system with progressive prime-vendor involvement essentially doubled total aggregate inventory turnover. A 46.5% reduction in standing inventory levels occurred. The drug cost per line item dispersed remained relatively constant over the one-year period, despite price increases. The application of the computerized ABC/EOQ inventory model to an online perpetual inventory control data base effectively reduced the inventory operation costs.

  11. 48 CFR 49.602-2 - Inventory forms.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Inventory forms. 49.602-2... TERMINATION OF CONTRACTS Contract Termination Forms and Formats 49.602-2 Inventory forms. Standard Form (SF) 1428, Inventory Disposal Schedule, and SF 1429, Inventory Disposal Schedule—Continuation Sheet,...

  12. 41 CFR 109-1.5108-3 - Stores inventories.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Stores inventories. 109....51-Personal Property Management Standards and Practices § 109-1.5108-3 Stores inventories. Perpetual inventory records are to be maintained for stores inventory items....

  13. 41 CFR 109-27.5104-3 - Perpetual inventory records.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Perpetual inventory... PROCUREMENT 27-INVENTORY MANAGEMENT 27.51-Management of Precious Metals § 109-27.5104-3 Perpetual inventory records. Perpetual inventory records shall be maintained as specified in Chapter V of DOE Order...

  14. 27 CFR 19.250 - Inventory reserve account.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Inventory reserve account....250 Inventory reserve account. (a) The proprietor may establish an inventory reserve account for any eligible distilled spirits product by maintaining an inventory reserve record as prescribed by §...

  15. 41 CFR 101-27.208 - Inventory analyses.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Inventory analyses. 101... Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 27-INVENTORY MANAGEMENT 27.2-Management of Shelf-Life Materials § 101-27.208 Inventory analyses. (a) An inventory analysis shall...

  16. 27 CFR 19.394 - Inventory of denatured spirits.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Inventory of denatured... of Articles Rules for Restoration and Redenaturation, Inventories, and Manufacture of Articles; Records Required § 19.394 Inventory of denatured spirits. A proprietor must take a physical inventory...

  17. 48 CFR 1245.508-2 - Reporting results of inventories.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... inventories. 1245.508-2 Section 1245.508-2 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION... 1245.508-2 Reporting results of inventories. The inventory report shall also include the following: (a) Name and title of the individual(s) that performed the physical inventory; (b) An itemized,...

  18. 48 CFR 3045.508-2 - Reporting results of inventories.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... inventories. 3045.508-2 Section 3045.508-2 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND... inventories. The inventory report shall also include the following: (a) Name and title of the individual(s) that performed the physical inventory; (b) An itemized, categorized listing of all property...

  19. 27 CFR 46.202 - Physical inventory requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Physical inventory... Cigarette Tubes Held for Sale on April 1, 2009 Inventories § 46.202 Physical inventory requirements. The dealer's physical inventory must result in a written record of: (a) The quantity and type of each...

  20. 48 CFR 49.602-2 - Inventory forms.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Inventory forms. 49.602-2... TERMINATION OF CONTRACTS Contract Termination Forms and Formats 49.602-2 Inventory forms. Standard Form (SF) 1428, Inventory Disposal Schedule, and SF 1429, Inventory Disposal Schedule—Continuation Sheet,...