Science.gov

Sample records for agreement ast 88-09616

  1. Aspartate aminotransferase (AST) blood test

    MedlinePlus

    ... mono") Muscle disease or trauma Swollen and inflamed pancreas ( pancreatitis ) AST level may also increase after: Burns (deep) Heart procedures Seizure Surgery Pregnancy and exercise may also cause an increased AST level.

  2. Leak prevention critical for ASTs

    SciTech Connect

    Edwards, B.

    1994-08-01

    Aboveground storage tanks can be crafted to prevent leaks caused by vandalism, overfill accidents and faulty valves. New designs and safety devices available in aboveground storage tanks (ASTs) have made ASTs viable option for owners of commercial, institutional and governmental facilities with storage needs of less than 20,000 gallons.

  3. AST Combustion Workshop: Diagnostics Working Group Report

    NASA Technical Reports Server (NTRS)

    Locke, Randy J.; Hicks, Yolanda R.; Hanson, Ronald K.

    1996-01-01

    A workshop was convened under NASA's Advanced Subsonics Technologies (AST) Program. Many of the principal combustion diagnosticians from industry, academia, and government laboratories were assembled in the Diagnostics/Testing Subsection of this workshop to discuss the requirements and obstacles to the successful implementation of advanced diagnostic techniques to the test environment of the proposed AST combustor. The participants, who represented the major relevant areas of advanced diagnostic methods currently applied to combustion and related fields, first established the anticipated AST combustor flowfield conditions. Critical flow parameters were then examined and prioritized as to their importance to combustor/fuel injector design and manufacture, environmental concerns, and computational interests. Diagnostic techniques were then evaluated in terms of current status, merits and obstacles for each flow parameter. All evaluations are presented in tabular form and recommendations are made on the best-suited diagnostic method to implement for each flow parameter in order of applicability and intrinsic value.

  4. astLib: Tools for research astronomers

    NASA Astrophysics Data System (ADS)

    Hilton, Matt; Boada, Steven

    2016-07-01

    astLib is a set of Python modules for performing astronomical plots, some statistics, common calculations, coordinate conversions, and manipulating FITS images with World Coordinate System (WCS) information through PyWCSTools, a simple wrapping of WCSTools (ascl:1109.015).

  5. ASteCA: Automated Stellar Cluster Analysis

    NASA Astrophysics Data System (ADS)

    Perren, G. I.; Vázquez, R. A.; Piatti, A. E.

    2015-04-01

    We present the Automated Stellar Cluster Analysis package (ASteCA), a suit of tools designed to fully automate the standard tests applied on stellar clusters to determine their basic parameters. The set of functions included in the code make use of positional and photometric data to obtain precise and objective values for a given cluster's center coordinates, radius, luminosity function and integrated color magnitude, as well as characterizing through a statistical estimator its probability of being a true physical cluster rather than a random overdensity of field stars. ASteCA incorporates a Bayesian field star decontamination algorithm capable of assigning membership probabilities using photometric data alone. An isochrone fitting process based on the generation of synthetic clusters from theoretical isochrones and selection of the best fit through a genetic algorithm is also present, which allows ASteCA to provide accurate estimates for a cluster's metallicity, age, extinction and distance values along with its uncertainties. To validate the code we applied it on a large set of over 400 synthetic MASSCLEAN clusters with varying degrees of field star contamination as well as a smaller set of 20 observed Milky Way open clusters (Berkeley 7, Bochum 11, Czernik 26, Czernik 30, Haffner 11, Haffner 19, NGC 133, NGC 2236, NGC 2264, NGC 2324, NGC 2421, NGC 2627, NGC 6231, NGC 6383, NGC 6705, Ruprecht 1, Tombaugh 1, Trumpler 1, Trumpler 5 and Trumpler 14) studied in the literature. The results show that ASteCA is able to recover cluster parameters with an acceptable precision even for those clusters affected by substantial field star contamination. ASteCA is written in Python and is made available as an open source code which can be downloaded ready to be used from its official site.

  6. Bridging the UST/AST gap

    SciTech Connect

    1995-10-01

    Choosing between underground and aboveground storage tank options can be a daunting--and risky--enterprise. Although USTs are conveniently out of sight, they cannot remain out of mind, and must be monitored continuously for possible unseen leaks or structural damage. ASTs provide easy access for monitoring and maintenance, but this benefit makes them open targets for vandalism, accidents and long-term effects of exposure to the elements. CON/SPAN{reg_sign} Bridge Systems, Dayton, Ohio, in association with the Dayton-based engineering firm LJB Inc., developed a unique solution to the AST/UST dilemma by adapting the company`s modular-concrete bridge construction technology to storage tank installation.

  7. AstRoMap European Astrobiology Roadmap.

    PubMed

    Horneck, Gerda; Walter, Nicolas; Westall, Frances; Grenfell, John Lee; Martin, William F; Gomez, Felipe; Leuko, Stefan; Lee, Natuschka; Onofri, Silvano; Tsiganis, Kleomenis; Saladino, Raffaele; Pilat-Lohinger, Elke; Palomba, Ernesto; Harrison, Jesse; Rull, Fernando; Muller, Christian; Strazzulla, Giovanni; Brucato, John R; Rettberg, Petra; Capria, Maria Teresa

    2016-03-01

    The European AstRoMap project (supported by the European Commission Seventh Framework Programme) surveyed the state of the art of astrobiology in Europe and beyond and produced the first European roadmap for astrobiology research. In the context of this roadmap, astrobiology is understood as the study of the origin, evolution, and distribution of life in the context of cosmic evolution; this includes habitability in the Solar System and beyond. The AstRoMap Roadmap identifies five research topics, specifies several key scientific objectives for each topic, and suggests ways to achieve all the objectives. The five AstRoMap Research Topics are • Research Topic 1: Origin and Evolution of Planetary Systems • Research Topic 2: Origins of Organic Compounds in Space • Research Topic 3: Rock-Water-Carbon Interactions, Organic Synthesis on Earth, and Steps to Life • Research Topic 4: Life and Habitability • Research Topic 5: Biosignatures as Facilitating Life Detection It is strongly recommended that steps be taken towards the definition and implementation of a European Astrobiology Platform (or Institute) to streamline and optimize the scientific return by using a coordinated infrastructure and funding system.

  8. AST Composite Wing Program: Executive Summary

    NASA Technical Reports Server (NTRS)

    Karal, Michael

    2001-01-01

    The Boeing Company demonstrated the application of stitched/resin infused (S/RFI) composite materials on commercial transport aircraft primary wing structures under the Advanced Subsonic technology (AST) Composite Wing contract. This report describes a weight trade study utilizing a wing torque box design applicable to a 220-passenger commercial aircraft and was used to verify the weight savings a S/RFI structure would offer compared to an identical aluminum wing box design. This trade study was performed in the AST Composite Wing program, and the overall weight savings are reported. Previous program work involved the design of a S/RFI-base-line wing box structural test component and its associated testing hardware. This detail structural design effort which is known as the "semi-span" in this report, was completed under a previous NASA contract. The full-scale wing design was based on a configuration for a MD-90-40X airplane, and the objective of this structural test component was to demonstrate the maturity of the S/RFI technology through the evaluation of a full-scale wing box/fuselage section structural test. However, scope reductions of the AST Composite Wing Program pre-vented the fabrication and evaluation of this wing box structure. Results obtained from the weight trade study, the full-scale test component design effort, fabrication, design development testing, and full-scale testing of the semi-span wing box are reported.

  9. AstRoMap European Astrobiology Roadmap.

    PubMed

    Horneck, Gerda; Walter, Nicolas; Westall, Frances; Grenfell, John Lee; Martin, William F; Gomez, Felipe; Leuko, Stefan; Lee, Natuschka; Onofri, Silvano; Tsiganis, Kleomenis; Saladino, Raffaele; Pilat-Lohinger, Elke; Palomba, Ernesto; Harrison, Jesse; Rull, Fernando; Muller, Christian; Strazzulla, Giovanni; Brucato, John R; Rettberg, Petra; Capria, Maria Teresa

    2016-03-01

    The European AstRoMap project (supported by the European Commission Seventh Framework Programme) surveyed the state of the art of astrobiology in Europe and beyond and produced the first European roadmap for astrobiology research. In the context of this roadmap, astrobiology is understood as the study of the origin, evolution, and distribution of life in the context of cosmic evolution; this includes habitability in the Solar System and beyond. The AstRoMap Roadmap identifies five research topics, specifies several key scientific objectives for each topic, and suggests ways to achieve all the objectives. The five AstRoMap Research Topics are • Research Topic 1: Origin and Evolution of Planetary Systems • Research Topic 2: Origins of Organic Compounds in Space • Research Topic 3: Rock-Water-Carbon Interactions, Organic Synthesis on Earth, and Steps to Life • Research Topic 4: Life and Habitability • Research Topic 5: Biosignatures as Facilitating Life Detection It is strongly recommended that steps be taken towards the definition and implementation of a European Astrobiology Platform (or Institute) to streamline and optimize the scientific return by using a coordinated infrastructure and funding system. PMID:27003862

  10. AstRoMap European Astrobiology Roadmap

    PubMed Central

    Horneck, Gerda; Westall, Frances; Grenfell, John Lee; Martin, William F.; Gomez, Felipe; Leuko, Stefan; Lee, Natuschka; Onofri, Silvano; Tsiganis, Kleomenis; Saladino, Raffaele; Pilat-Lohinger, Elke; Palomba, Ernesto; Harrison, Jesse; Rull, Fernando; Muller, Christian; Strazzulla, Giovanni; Brucato, John R.; Rettberg, Petra; Capria, Maria Teresa

    2016-01-01

    Abstract The European AstRoMap project (supported by the European Commission Seventh Framework Programme) surveyed the state of the art of astrobiology in Europe and beyond and produced the first European roadmap for astrobiology research. In the context of this roadmap, astrobiology is understood as the study of the origin, evolution, and distribution of life in the context of cosmic evolution; this includes habitability in the Solar System and beyond. The AstRoMap Roadmap identifies five research topics, specifies several key scientific objectives for each topic, and suggests ways to achieve all the objectives. The five AstRoMap Research Topics are • Research Topic 1: Origin and Evolution of Planetary Systems• Research Topic 2: Origins of Organic Compounds in Space• Research Topic 3: Rock-Water-Carbon Interactions, Organic Synthesis on Earth, and Steps to Life• Research Topic 4: Life and Habitability• Research Topic 5: Biosignatures as Facilitating Life Detection It is strongly recommended that steps be taken towards the definition and implementation of a European Astrobiology Platform (or Institute) to streamline and optimize the scientific return by using a coordinated infrastructure and funding system. Key Words: Astrobiology roadmap—Europe—Origin and evolution of life—Habitability—Life detection—Life in extreme environments. Astrobiology 16, 201–243. PMID:27003862

  11. Elements of F-ast proton decay

    NASA Astrophysics Data System (ADS)

    Li, Tianjun; Nanopoulos, Dimitri V.; Walker, Joel W.

    2011-05-01

    Gauge coupling unification in the Minimal Supersymmetric Standard Model (MSSM) strongly suggests the existence of a Grand Unified Theory (GUT), which could be probed by the observation of proton decay. Proton lifetime in the p→(π dimension six mode is proportional in the fourth power to the GUT mass scale, and inversely proportional in the fourth power to the GUT coupling. Flipped SU(5) with strict MSSM field content is known to survive existing null detection limits for proton decay approaching 10 years, and indeed, the lifetime predicted by prior studies can be so long that successful detection is not currently plausible. We provide an updated dictionary of solutions for the relevant flipped unification parameters with generic β-function coefficients, significantly upgrading the level of detail with which second order effects are treated, and correcting subtle published errors. Recently studied classes of F-theory derived GUT models postulate additional vector-like multiplets at the TeV scale which modify the renormalization group to yield a substantial increase in the SU(3×SU(2 unified coupling. In conjunction with the naturally depressed F-lipped SU(5) partial unification mass M, the F-resh analysis undertaken predicts comparatively F-ast proton decay which only narrowly evades existing detection limits, and likely falls within the observable range of proposed next generation detectors such as DUSEL and Hyper-Kamiokande. The TeV-scale vector multiplets are themselves suitable for cross correlation by the Large Hadron Collider. Their presence moreover magnifies the gap between the dual mass scales of Flipped SU(5), allowing for an elongated second stage renormalization, pushing the F-inal grand unification to the doorstep of the reduced Planck mass.

  12. DynAstVO : the Europlanet orbital asteroid database

    NASA Astrophysics Data System (ADS)

    Desmars, Josselin; Thuillot, William; Hestroffer, Daniel J.; David, Pedro

    2016-10-01

    DynAstVO is a new orbital database dedicated to Near Earth Asteroid orbits, developed within the Europlanet 2020 RI framework.It provides parameters of asteroid orbits: orbital elements, observational information, minimum distance with Earth and planets, ephemeris and in particular, orbit uncertainty and associated covariance matrix.This database is updated daily on the basis of the Minor Planet Electronic Circulars.Orbit determination and improvement is computed as soon as new observations are available or an object is discovered.This database conforms to EPN-TAP environment (Erard et al. 2015, A&C 7) and is accessible through VO protocols or classical web access. Auxiliary data such as SPICE kernels for their ephemerides are provided.Finally, we present a comparison with other classical databases such as Astorb or MPCORB.Acknowledgements: This work is done in the framework of Europlanet 2020 RI which has received fundingfrom the European Union's Horizon 2020 research and innovation programme under grant agreement No 654208.

  13. Fusarium sambucinum astA gene expressed during potato infection is a functional orthologue of Aspergillus nidulans astA.

    PubMed

    Piłsyk, Sebastian; Natorff, Renata; Gawińska-Urbanowicz, Hanna; Kruszewska, Joanna S

    2015-06-01

    Sulfate assimilation plays a vital role in prototrophic organisms. Orthologues of the alternative sulfate transporter (AstA) gene from Aspergillus nidulans were identified in the fungal plant pathogens Fusarium sambucinum and Fusarium graminearum. By physiological and biochemical analyses, the AstA orthologues were determined to be able to uptake sulfate from the environment. Similarly to astA in A. nidulans, the FsastA gene was found to be regulated by sulfur metabolite repression (SMR) in a sulfur-dependent manner. In contrast, the FgastA transcript was undetectable, however, when the FgastA gene was expressed heterologously in A. nidulans, the translated FgAstA protein acted as a sulfate transporter. Interestingly, F. sambucinum astA expression was remarkably augmented in infected potato tubers, despite the presence abundant sulfate and was found not to be correlated with plant resistance.

  14. Fusarium sambucinum astA gene expressed during potato infection is a functional orthologue of Aspergillus nidulans astA.

    PubMed

    Piłsyk, Sebastian; Natorff, Renata; Gawińska-Urbanowicz, Hanna; Kruszewska, Joanna S

    2015-06-01

    Sulfate assimilation plays a vital role in prototrophic organisms. Orthologues of the alternative sulfate transporter (AstA) gene from Aspergillus nidulans were identified in the fungal plant pathogens Fusarium sambucinum and Fusarium graminearum. By physiological and biochemical analyses, the AstA orthologues were determined to be able to uptake sulfate from the environment. Similarly to astA in A. nidulans, the FsastA gene was found to be regulated by sulfur metabolite repression (SMR) in a sulfur-dependent manner. In contrast, the FgastA transcript was undetectable, however, when the FgastA gene was expressed heterologously in A. nidulans, the translated FgAstA protein acted as a sulfate transporter. Interestingly, F. sambucinum astA expression was remarkably augmented in infected potato tubers, despite the presence abundant sulfate and was found not to be correlated with plant resistance. PMID:25986548

  15. AST: A library for modelling and manipulating coordinate systems

    NASA Astrophysics Data System (ADS)

    Berry, David S.; Warren-Smith, Rodney F.; Jenness, Tim

    2016-04-01

    In view of increased interest in object-oriented systems for describing coordinate information, we present a description of the data model used by the Starlink AST library. AST provides a comprehensive range of facilities for attaching world co-ordinate systems to astronomical data, and for retrieving and interpreting that information in a variety of formats, including FITS-WCS. AST is a mature system that has been in use for more than 17 years, and may consequently be useful as a means of informing development of similar systems in the future.

  16. Performance of the Microwave Anisotropy Probe AST-201 Star Trackers

    NASA Technical Reports Server (NTRS)

    Ward, David K.; vanBezooijen, Roelof; Bauer, Frank H. (Technical Monitor)

    2002-01-01

    The Microwave Anisotropy Probe (MAP) was launched to create a full-sky map of the cosmic microwave background. MAP incorporates two modified Lockheed Martin AST-201 (Autonomous Star Tracker) star trackers. The AST-201 employs an eight element radiation hardened lens assembly which is used to focus an image on a charge coupled device (CCD). The CCD image is then processed by a star identification algorithm which outputs a three-axis attitude. A CCD-shift algorithm called Time Delayed Integration (TDI) was also included in each star tracker. In order to provide some radiation effect filtering during MAP's three to five phasing loop passes through the Van Allen radiation belts, a simple pixel filtering scheme was implemented, rather than using a more complex, but more robust windowing algorithm. The trackers also include a fiber optic data interface. This paper details the ground testing that was accomplished on the MAP trackers.

  17. Generating a Magellanic star cluster catalog with ASteCA

    NASA Astrophysics Data System (ADS)

    Perren, G. I.; Piatti, A. E.; Vázquez, R. A.

    2016-08-01

    An increasing number of software tools have been employed in the recent years for the automated or semi-automated processing of astronomical data. The main advantages of using these tools over a standard by-eye analysis include: speed (particularly for large databases), homogeneity, reproducibility, and precision. At the same time, they enable a statistically correct study of the uncertainties associated with the analysis, in contrast with manually set errors, or the still widespread practice of simply not assigning errors. We present a catalog comprising 210 star clusters located in the Large and Small Magellanic Clouds, observed with Washington photometry. Their fundamental parameters were estimated through an homogeneous, automatized and completely unassisted process, via the Automated Stellar Cluster Analysis package ( ASteCA). Our results are compared with two types of studies on these clusters: one where the photometry is the same, and another where the photometric system is different than that employed by ASteCA.

  18. M4AST - A Tool for Asteroid Modelling

    NASA Astrophysics Data System (ADS)

    Birlan, Mirel; Popescu, Marcel; Irimiea, Lucian; Binzel, Richard

    2016-10-01

    M4AST (Modelling for asteroids) is an online tool devoted to the analysis and interpretation of reflection spectra of asteroids in the visible and near-infrared spectral intervals. It consists into a spectral database of individual objects and a set of routines for analysis which address scientific aspects such as: taxonomy, curve matching with laboratory spectra, space weathering models, and mineralogical diagnosis. Spectral data were obtained using groundbased facilities; part of these data are precompiled from the literature[1].The database is composed by permanent and temporary files. Each permanent file contains a header and two or three columns (wavelength, spectral reflectance, and the error on spectral reflectance). Temporary files can be uploaded anonymously, and are purged for the property of submitted data. The computing routines are organized in order to accomplish several scientific objectives: visualize spectra, compute the asteroid taxonomic class, compare an asteroid spectrum with similar spectra of meteorites, and computing mineralogical parameters. One facility of using the Virtual Observatory protocols was also developed.A new version of the service was released in June 2016. This new release of M4AST contains a database and facilities to model more than 6,000 spectra of asteroids. A new web-interface was designed. This development allows new functionalities into a user-friendly environment. A bridge system of access and exploiting the database SMASS-MIT (http://smass.mit.edu) allows the treatment and analysis of these data in the framework of M4AST environment.Reference:[1] M. Popescu, M. Birlan, and D.A. Nedelcu, "Modeling of asteroids: M4AST," Astronomy & Astrophysics 544, EDP Sciences, pp. A130, 2012.

  19. Coastal Atmosphere and Sea Time Series (CoASTS)

    NASA Technical Reports Server (NTRS)

    Hooker, Stanford B. (Editor); Firestone, Elaine R. (Editor); Zibordi, Giuseppe; Berthon, Jean-Francoise; Doyle, John P.; Grossi, Stefania; vanderLinde, Dirk; Targa, Cristina; Alberotanza, Luigi; McClain, Charles R. (Technical Monitor)

    2002-01-01

    The Coastal Atmosphere and Sea Time Series (CoASTS) Project aimed at supporting ocean color research and applications, from 1995 up to the time of publication of this document, has ensured the collection of a comprehensive atmospheric and marine data set from an oceanographic tower located in the northern Adriatic Sea. The instruments and the measurement methodologies used to gather quantities relevant for bio-optical modeling and for the calibration and validation of ocean color sensors, are described. Particular emphasis is placed on four items: (1) the evaluation of perturbation effects in radiometric data (i.e., tower-shading, instrument self-shading, and bottom effects); (2) the intercomparison of seawater absorption coefficients from in situ measurements and from laboratory spectrometric analysis on discrete samples; (3) the intercomparison of two filter techniques for in vivo measurement of particulate absorption coefficients; and (4) the analysis of repeatability and reproducibility of the most relevant laboratory measurements carried out on seawater samples (i.e., particulate and yellow substance absorption coefficients, and pigment and total suspended matter concentrations). Sample data are also presented and discussed to illustrate the typical features characterizing the CoASTS measurement site in view of supporting the suitability of the CoASTS data set for bio-optical modeling and ocean color calibration and validation.

  20. Submillimeter Astronomy from the South Pole (AST/RO)

    NASA Astrophysics Data System (ADS)

    Stark, Antony A.

    2013-01-01

    The Antarctic Submillimeter Telescope and Remote Observatory (AST/RO), a 1.7 m diameter offset Gregorian telescope for astronomy and aeronomy studies at wavelengths between 200 and 2000 μm, saw first light in 1995 and operated until 2005. It was the first radio telescope to operate continuously throughout the winter on the Antarctic Plateau. It served as a site testing instrument and prototype for later instruments, as well as executing a wide variety of scientific programs that resulted in six doctoral theses and more than one hundred scientific publications. The South Pole environment is unique among observatory sites for unusually low wind speeds, low absolute humidity, and the consistent clarity of the submillimeter sky. Especially significant are the exceptionally low values of sky noise found at this site, a result of the small water vapor content of the atmosphere. Multiple submillimeter-wave and Terahertz detector systems were in operation on AST/RO, including heterodyne and bolometric arrays. AST/RO's legacy includes comprehensive submillimeter-wave site testing of the South Pole, spectroscopic studies of 492 GHz and 809 GHz neutral atomic carbon and 460 GHz and 806 GHz carbon monoxide in the Milky Way and Magellanic Clouds, and the first detection of the 1.46 THz [N II] line from a ground-based observatory.

  1. Identification of antifungal compounds produced by Lactobacillus casei AST18.

    PubMed

    Li, Hongjuan; Liu, Lu; Zhang, Shuwen; Cui, Wenming; Lv, Jiaping

    2012-08-01

    Lactobacillus casei AST18 was screened as an antifungal lactic acid bacteria which we have reported before. In this research, the antifungal properties of cell-free culture filtrate (CCF) from L. casei AST18 were detected, and the antifungal compounds of CCF were prepared by ultrafiltration, and semi-preparative HPLC, and then determined by GC-MS. CCF was sensitive to pH and heat treatment but it was not affected by the treatment of trypsin and pepsin. Through the treatment of ultrafiltration and semi-preparative HPLC there were two parts of CCF which showed antifungal activities: part 1 and part 4. Lactic acid was identified as the main antifungal compound in part 1. In part 4, three small molecular substances were detected with GC-MS. The three potential antifungal substances were cyclo-(Leu-Pro), 2,6-diphenyl-piperidine, and 5,10-diethoxy-2,3,7,8-tetrahydro-1H,6H-dipyrrolo[1,2-a;1',2'-d]pyrazine. The antifungal activity of L. casei AST18 was a synergistic effect of lactic acid and cyclopeptides. PMID:22580887

  2. Expression and purification of a functional recombinant aspartate aminotransferase (AST) from Escherichia coli.

    PubMed

    Zou, Lihui; Zhao, Haijian; Wang, Daguang; Wang, Meng; Zhang, Chuanbao; Xiao, Fei

    2014-07-01

    Aspartate aminotransferase (AST; E.C. 2.6.1.1), a vitamin B6-dependent enzyme, preferentially promotes the mutual transformation of aspartate and α-ketoglutarate to oxaloacetate and glutamate. It plays a key role in amino acid metabolism and has been widely recommended as a biomarker of liver and heart damage. Our study aimed to evaluate the extensive preparation of AST and its application in quality control in clinical laboratories. We describe a scheme to express and purify the 6His-AST fusion protein. An optimized sequence coding AST was synthesized and transformed into Escherichia coli BL21 (DE3) strain for protein expression. Ideally, the fusion protein has a volumetric productivity achieving 900 mg/l cultures. After affinity chromatography, the enzyme activity of purified AST reached 150,000 U/L. Commutability assessment between the engineered AST and standard AST from Roche suggested that the engineered AST was the better candidate for the reference material. Moreover, the AST showed high stability during long-term storage at -20ºC. In conclusion, the highly soluble 6His-tagged AST can become a convenient tool for supplying a much better and cheaper standard or reference material for the clinical laboratory. PMID:24722375

  3. AST-120 Improves Microvascular Endothelial Dysfunction in End-Stage Renal Disease Patients Receiving Hemodialysis

    PubMed Central

    Ryu, Jung-Hwa; Yu, Mina; Lee, Sihna; Ryu, Dong-Ryeol; Kim, Seung-Jung; Kang, Duk-Hee

    2016-01-01

    Purpose Endothelial dysfunction (ED) is a pivotal phenomenon in the development of cardiovascular disease (CVD) in patients receiving hemodialysis (HD). Indoxyl sulfate (IS) is a known uremic toxin that induces ED in patients with chronic kidney disease. The aim of this study was to investigate whether AST-120, an absorbent of IS, improves microvascular or macrovascular ED in HD patients. Materials and Methods We conducted a prospective, case-controlled trial. Fourteen patients each were enrolled in respective AST-120 and control groups. The subjects in the AST-120 group were treated with AST-120 (6 g/day) for 6 months. Microvascular function was assessed by laser Doppler flowmetry using iontophoresis of acetylcholine (Ach) and sodium nitroprusside (SNP) at baseline and again at 3 and 6 months. Carotid arterial intima-media thickness (cIMT) and flow-mediated vasodilation were measured at baseline and 6 months. The Wilcoxon rank test was used to compare values before and after AST-120 treatment. Results Ach-induced iontophoresis (endothelium-dependent response) was dramatically ameliorated at 3 months and 6 months in the AST-120 group. SNP-induced response showed delayed improvement only at 6 months in the AST-120 group. The IS level was decreased at 3 months in the AST-120 group, but remained stable thereafter. cIMT was significantly reduced after AST-120 treatment. No significant complications in patients taking AST-120 were reported. Conclusion AST-120 ameliorated microvascular ED and cIMT in HD patients. A randomized study including a larger population will be required to establish a definitive role of AST-120 as a preventive medication for CVD in HD patients. PMID:27189289

  4. Coastal Atmosphere and Sea Time Series (CoASTS)

    NASA Technical Reports Server (NTRS)

    Hooker, Stanford B. (Editor); Firestone, Elaine R. (Editor); Berthon, Jean-Francoise; Zibordi, Giuseppe; Doyle, John P.; Grossi, Stefania; vanderLinde, Dirk; Targa, Cristina; McClain, Charles R. (Technical Monitor)

    2002-01-01

    In this document, the first three years of a time series of bio-optical marine and atmospheric measurements are presented and analyzed. These measurements were performed from an oceanographic tower in the northern Adriatic Sea within the framework of the Coastal Atmosphere and Sea Time Series (CoASTS) project, an ocean color calibration and validation activity. The data set collected includes spectral measurements of the in-water apparent (diffuse attenuation coefficient, reflectance, Q-factor, etc.) and inherent (absorption and scattering coefficients) optical properties, as well as the concentrations of the main optical components (pigment and suspended matter concentrations). Clear seasonal patterns are exhibited by the marine quantities on which an appreciable short-term variability (on the order of a half day to one day) is superimposed. This short-term variability is well correlated with the changes in salinity at the surface resulting from the southward transport of freshwater coming from the northern rivers. Concentrations of chlorophyll alpha and total suspended matter span more than two orders of magnitude. The bio-optical characteristics of the measurement site pertain to both Case-I (about 64%) and Case-II (about 36%) waters, based on a relationship between the beam attenuation coefficient at 660nm and the chlorophyll alpha concentration. Empirical algorithms relating in-water remote sensing reflectance ratios and optical components or properties of interest (chlorophyll alpha, total suspended matter, and the diffuse attenuation coefficient) are presented.

  5. The AST/ALT (De-Ritis) ratio

    PubMed Central

    Rief, Peter; Pichler, Martin; Raggam, Reinhard; Hafner, Franz; Gerger, Armin; Eller, Philipp; Brodmann, Marianne; Gary, Thomas

    2016-01-01

    Abstract The aspartat aminotransferase (AST)/alanin aminotransferase (ALT) (De-Ritis) ratio (AAR) is an easily applicable blood test. An elevated AAR on the one hand has been associated with an increase in nonalcoholic fatty liver disease (NAFLD). NAFLD on the other hand is associated with an increase in cardiovascular disease, all-cause mortality, and diabetes. As the AAR is also elevated in case of muscular damage, we investigated AAR and its association with critical limb ischemia (CLI) in peripheral arterial occlusive disease (PAOD) patients. In our cross-sectional study, we included 1782 PAOD patients treated at our institution from 2005 to 2010. Patients with chronic alcohol consumption (>20 g/day) were excluded. AAR was calculated and the cohort was categorized into tertiles according to the AAR. An optimal cut-off value for the continuous AAR was calculated by applying a receiver operating curve analysis to discriminate between CLI and non-CLI. In our cohort, occurrence of CLI significantly increased with an elevation in AAR. As an optimal cut-off value, an AAR of 1.67 (sensitivity 34.1%, specificity 81.0%) was identified. Two groups were categorized, 1st group containing 1385 patients (AAR < 1.67) and a 2nd group with 397 patients (AAR > 1.67). CLI was more frequent in AAR > 1.67 patients (166 [41.9%]) compared to AAR < 1.67 patients (329 [23.8%]) (P < 0.001), as was prior myocardial infarction (28 [7.1%] vs 54 [3.9%], P = 0.01). Regarding inflammatory parameters, C-reactive protein (median 8.1 mg/L [2.9–28.23] vs median 4.3 mg/L [2.0–11.5]) and fibrinogen (median 427.5 mg/dL [344.25–530.0] vs 388.0 mg/dL [327.0–493.0]) also significantly differed in the 2 patient groups (both P < 0.001). Finally, an AAR > 1.67 was associated with an odds ratio (OR) of 2.0 (95% confidence interval [CI] 1.7–2.3) for CLI even after adjustment for other well-established vascular risk factors. An increased AAR is significantly

  6. AST/ASTS workshop on increasing organ donation in the United States: creating an "arc of change" from removing disincentives to testing incentives.

    PubMed

    Salomon, D R; Langnas, A N; Reed, A I; Bloom, R D; Magee, J C; Gaston, R S

    2015-05-01

    The American Society of Transplantation (AST) and American Society of Transplant Surgeons (ASTS) convened a workshop on June 2-3, 2014, to explore increasing both living and deceased organ donation in the United States. Recent articles in the lay press on illegal organ sales and transplant tourism highlight the impact of the current black market in kidneys that accompanies the growing global organ shortage. We believe it important not to conflate the illegal market for organs, which we reject in the strongest possible terms, with the potential in the United States for concerted action to remove all remaining financial disincentives for donors and critically consider testing the impact and acceptability of incentives to increase organ availability in the United States. However, we do not support any trials of direct payments or valuable considerations to donors or families based on a process of market-assigned values of organs. This White Paper represents a summary by the authors of the deliberations of the Incentives Workshop Group and has been approved by both AST and ASTS Boards.

  7. AST/ASTS workshop on increasing organ donation in the United States: creating an "arc of change" from removing disincentives to testing incentives.

    PubMed

    Salomon, D R; Langnas, A N; Reed, A I; Bloom, R D; Magee, J C; Gaston, R S

    2015-05-01

    The American Society of Transplantation (AST) and American Society of Transplant Surgeons (ASTS) convened a workshop on June 2-3, 2014, to explore increasing both living and deceased organ donation in the United States. Recent articles in the lay press on illegal organ sales and transplant tourism highlight the impact of the current black market in kidneys that accompanies the growing global organ shortage. We believe it important not to conflate the illegal market for organs, which we reject in the strongest possible terms, with the potential in the United States for concerted action to remove all remaining financial disincentives for donors and critically consider testing the impact and acceptability of incentives to increase organ availability in the United States. However, we do not support any trials of direct payments or valuable considerations to donors or families based on a process of market-assigned values of organs. This White Paper represents a summary by the authors of the deliberations of the Incentives Workshop Group and has been approved by both AST and ASTS Boards. PMID:25833653

  8. [Evaluation of the VITEK 2 system (AST-YSO1 cards) for antifungal susceptibility testing against different Candida species].

    PubMed

    Ochiuzzi, María E; Arechavala, Alicia; Guelfand, Liliana; Maldonado, Ivana; Soloaga, Rolando

    2014-01-01

    The aim of this investigation was to evaluate the results of antifungal susceptibility for various Candida species using the Vitek 2 semi-automated system (AST-YSO1 cards, bioMérieux), and to compare them with those obtained by the CLSI (Clinical and Laboratory Standards Institute) broth microdilution reference method (Document M27-A3,2008). The essential agreement (EA) was > 90%, except for Candida glabrata against voriconazole (VCZ); and for Candida krusei against fluconazole (FCZ). The overall categorical agreement (CA) was > 90% when FCZ was evaluated and 89.5% at 24h and 80.7% at 48 h for VCZ. The average time for obtaining results was 15.5h. Minor errors were 7.8% at 24h and 6.1% at 48 h for FCZ, and 10.5% at 24h and 19.3% at 48 h for VCZ. There was only one very major error for FCZ against Candida parapsilosis and no major errors were observed. For amphotericin B, only three isolates showed MICs ≥ 2 μg/ml. The Vitek 2 system detected the MIC value for various Candida species and showed excellent agreement with the reference method proposed by the CLSI.

  9. Advanced Supersonic Technology concept AST-100 characteristics developed in a baseline-update study

    NASA Technical Reports Server (NTRS)

    Baber, H. T., Jr.; Swanson, E. E.

    1976-01-01

    The advanced supersonic technology configuration, AST-100, is described. The combination of wing thickness reduction, nacelle recontouring for minimum drag at cruise, and the use of the horizontal tail to produce lift during climb and cruise resulted in an increase in maximum lift-to-drag ratio. Lighter engines and lower fuel weight associated with this resizing result in a six percent reduction in takeoff gross weight. The AST-100 takeoff maximum effective perceived noise at the runway centerline and sideline measurement stations was 114.4 decibels. Since 1.5-decibels tradeoff is available from the approach noise, the required engine noise supression is 4.9 decibels. The AST-100 largest maximum overpressure would occur during transonic climb acceleration when the aircraft was at relatively low altitude. Calculated standard +8 C day range of the AST-100, with a 292 passenger payload, is 7348 km (3968 n.mi). Fuel price is the largest contributor to direct operating cost. However, if the AST-100 were flown subsonically (M = 0.9), direct operating costs would increase approximately 50 percent because of time related costs.

  10. Report of the second joint meeting of ESOT and AST: current pipelines in biotech and pharma.

    PubMed

    van Gelder, Teun; Baan, Carla; Vincenti, Flavio; Mannon, Roslyn B

    2013-09-01

    Following the first joint meeting organized by the European (ESOT) and American (AST) Societies of Transplantation in 2010, a second joint meeting was held in Nice, France, on October 12-14, 2012 at the Palais de la Mediterannee. Co-chairs of the scientific advisory committee were Dr. Flavio Vincenti (AST) and Dr. Teun Van Gelder (ESOT). The goal was to discuss the key unmet needs in solid organ transplantation with the opportunity to interrelate current basic research efforts with clinical translation. Thus, the topic of this second meeting "Transformational therapies and diagnostics in transplantation" was devised and a summary of this meeting follows.

  11. Evaluation of the Alfred 60/AST Device as a Screening Test for Urinary Tract Infections

    PubMed Central

    Stathopoulos, George; Chan, Raymond C.; van Hal, Sebastiaan J.

    2013-01-01

    The performance of the Alfred 60/AST device, an automated bacterial culture device which uses laser nephelometry to detect and quantify bacterial growth, was evaluated. The instrument is effective at screening negative samples and is more reliable at detecting bacteria than yeasts. Microscopy can be used to reduce the false-negative numbers. PMID:23885005

  12. 21 CFR 862.1100 - Aspartate amino transferase (AST/SGOT) test system.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Aspartate amino transferase (AST/SGOT) test system. 862.1100 Section 862.1100 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY AND CLINICAL TOXICOLOGY DEVICES Clinical...

  13. 21 CFR 862.1100 - Aspartate amino transferase (AST/SGOT) test system.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Aspartate amino transferase (AST/SGOT) test system. 862.1100 Section 862.1100 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY AND CLINICAL TOXICOLOGY DEVICES Clinical...

  14. 21 CFR 862.1100 - Aspartate amino transferase (AST/SGOT) test system.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Aspartate amino transferase (AST/SGOT) test system. 862.1100 Section 862.1100 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY AND CLINICAL TOXICOLOGY DEVICES Clinical...

  15. 21 CFR 862.1100 - Aspartate amino transferase (AST/SGOT) test system.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Aspartate amino transferase (AST/SGOT) test system. 862.1100 Section 862.1100 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY AND CLINICAL TOXICOLOGY DEVICES Clinical...

  16. 21 CFR 862.1100 - Aspartate amino transferase (AST/SGOT) test system.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Aspartate amino transferase (AST/SGOT) test system. 862.1100 Section 862.1100 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY AND CLINICAL TOXICOLOGY DEVICES Clinical...

  17. The genetic architecture of liver enzyme levels: GGT, ALT and AST.

    PubMed

    van Beek, Jenny H D A; de Moor, Marleen H M; de Geus, Eco J C; Lubke, Gitta H; Vink, Jacqueline M; Willemsen, Gonneke; Boomsma, Dorret I

    2013-07-01

    High levels of liver enzymes GGT, ALT and AST are predictive of disease and all-cause mortality and can reflect liver injury, fatty liver and/or oxidative stress. Variation in GGT, ALT and AST levels is heritable. Moderation of the heritability of these liver enzymes by age and sex has not often been explored, and it is not clear to what extent non-additive genetic and shared environmental factors may play a role. To examine the genetic architecture of GGT, ALT and AST, plasma levels were assessed in a large sample of twins, their siblings, parents and spouses (N = 8,371; age range 18-90). For GGT and ALT, but not for AST, genetic structural equation modeling showed evidence for quantitative sex differences in the genetic architecture. There was no evidence for qualitative sex differences, i.e. the same genes were expressed in males and females. Both additive and non-additive genetic factors were important for GGT in females (total heritability h(2) 60 %) and AST in both sexes (total h(2) 43 %). The heritability of GGT in males and ALT for both sexes was due to additive effects only (GGT males 30 %; ALT males 40 %, females 22 %). Evidence emerged for shared environmental factors influencing GGT in the male offspring generation (variance explained 28 %). Thus, the same genes influence liver enzyme levels across sex and age, but their relative contribution to the variation in GGT and ALT differs in males and females and for GGT across age. Given adequate sample sizes these results suggest that genome-wide association studies may result in the detection of new susceptibility loci for liver enzyme levels when pooling results over sex and age. PMID:23580007

  18. Randomized Placebo-Controlled EPPIC Trials of AST-120 in CKD

    PubMed Central

    Berl, Tomas; Beck, Gerald J.; Remuzzi, Giuseppe; Ritz, Eberhard; Arita, Kiyoshi; Kato, Akira; Shimizu, Miho

    2015-01-01

    Reduced GFR in patients with CKD causes systemic accumulation of uremic toxins, which has been correlated with disease progression and increased morbidity. The orally administered spherical carbon adsorbent AST-120 reduces systemic toxin absorption through gastrointestinal sequestration, which may slow disease progression in these patients. The multinational, randomized, double-blind, placebo-controlled Evaluating Prevention of Progression in CKD (EPPIC)-1 and EPPIC-2 trials evaluated the effects of AST-120 on the progression of CKD when added to standard therapy. We randomly assigned 2035 adults with moderate to severe disease (serum creatinine at screening, 2.0–5.0 mg/dl for men and 1.5–5.0 mg/dl for women) to receive either placebo or AST-120 (9 g/d). The primary end point was a composite of dialysis initiation, kidney transplantation, and serum creatinine doubling. Each trial continued until accrual of 291 primary end points. The time to primary end point was similar between the AST-120 and the placebo groups in both trials (EPPIC-1: hazard ratio, 1.03; 95% confidence interval, 0.84 to 1.27; P=0.78) (EPPIC-2: hazard ratio, 0.91; 95% confidence interval, 0.74 to 1.12; P=0.37); a pooled analysis of both trials showed similar results. The estimated median time to primary end points for the placebo groups was 124 weeks for power calculations, but actual times were 189.0 and 170.3 weeks for EPPIC-1 and EPPIC-2, respectively. Thus, disease progression was more gradual than expected in the trial populations. In conclusion, the benefit of adding AST-120 to standard therapy in patients with moderate to severe CKD is not supported by these data. PMID:25349205

  19. Academic careers and lifestyle characteristics of 171 transplant surgeons in the ASTS.

    PubMed

    Florence, L S; Feng, S; Foster, C E; Fryer, J P; Olthoff, K M; Pomfret, E; Sheiner, P A; Sanfey, H; Bumgardner, G L

    2011-02-01

    This manuscript reports the demographics, education and training, professional activities and lifestyle characteristics of 171 members of the American Society of Transplant Surgeons (ASTS). ASTS members were sent a comprehensive survey by electronic mail. There were 171 respondents who were 49 ± 8 years of age and predominantly Caucasian males. Female transplant surgeons comprised 10% of respondents. ASTS respondents underwent 15.6 ± 1.0 years of education and training (including college, medical school, residency and transplantation fellowship) and had practiced for 14.7 ± 9.2 years. Clinical practice included kidney, pancreas and liver organ transplantation, living donor surgery, organ procurement, vascular access procedures and general surgery. Transplant surgeons also devote a significant amount of time to nonsurgical patient care, research, education and administration. Transplant surgeons, both male and female, reported working approximately 70 h/week and a median of 195 operative cases per year. The anticipated retirement age for men was 64.6 ± 8.6 and for women was 62.2 ± 4.2 years. This is the largest study to date assessing professional and lifestyle characteristics of abdominal transplant surgeons.

  20. On the N={1}^{ast } gauge theory on a circle and elliptic integrable systems

    NASA Astrophysics Data System (ADS)

    Bourget, Antoine; Troost, Jan

    2016-01-01

    We continue our study of the N={1}^{ast } supersymmetric gauge theory on R^{2,1}× {S}^1 and its relation to elliptic integrable systems. Upon compactification on a circle, we show that the semi-classical analysis of the massless and massive vacua depends on the classification of nilpotent orbits, as well as on the conjugacy classes of the component group of their centralizer. We demonstrate that semi-classically massless vacua can be lifted by Wilson lines in unbroken discrete gauge groups. The pseudo-Levi subalgebras that play a classifying role in the nilpotent orbit theory are also key in defining generalized Inozemtsev limits of (twisted) elliptic integrable systems. We illustrate our analysis in the N={1}^{ast } theories with gauge algebras su(3), su(4), so(5) and for the exceptional gauge algebra G 2. We map out modular duality diagrams of the massive and massless vacua. Moreover, we provide an analytic description of the branches of massless vacua in the case of the su(3) and the so(5) theory. The description of these branches in terms of the complexified Wilson lines on the circle invokes the Eichler-Zagier technique for inverting the elliptic Weierstrass function. After fine-tuning the coupling to elliptic points of order three, we identify the Argyres-Douglas singularities of the su(3) N={1}^{ast } theory.

  1. Peculiarities of vaporization of vitreous alloys of the As-Te system. Heat of formation of gaseous arsenic tellurides

    SciTech Connect

    Alikhanyan, A.S.; Steblevskii, A.V.; Gorgoraki, V.I.; Pashinkin, A.S.; Malyusov, V.A.

    1986-11-01

    Interpretation of the mass spectrum of the gas phase above vitreous alloys of the system As-Te showed virtual absence of AsTe molecules in the saturated vapor; to be precise, the content of these molecules does not exceed 5 x 10/sup -5/ Pa at 550 K. Taking this value as the upper limit of the partial pressure of AsTe, they determined, on the basis of the third law of thermodynamics, the limiting values of the enthalpy of formation and the energy of atomization of AsTe. The requisite values of the entropy of gaseous AsTe and the enthalpy of formation of As/sub (g)/ and Te/sub (g)/ were taken. The calculated results referred to 298.15 K are given. The energy of atomization of the AsTe molecule estimated thus agrees well with the value D/sub 298//sup 0/ (AsTe) = 307.2 kJ/mole calculated by the Pauling's equation with allowance for the electronegativities of arsenic and tellurium.

  2. Incremental Predictive Value of Serum AST-to-ALT Ratio for Incident Metabolic Syndrome: The ARIRANG Study

    PubMed Central

    Ahn, Song Vogue; Baik, Soon Koo; Cho, Youn zoo; Koh, Sang Baek; Huh, Ji Hye; Chang, Yoosoo; Sung, Ki-Chul; Kim, Jang Young

    2016-01-01

    Aims The ratio of aspartate aminotransferase (AST) to alanine aminotransferase (ALT) is of great interest as a possible novel marker of metabolic syndrome. However, longitudinal studies emphasizing the incremental predictive value of the AST-to-ALT ratio in diagnosing individuals at higher risk of developing metabolic syndrome are very scarce. Therefore, our study aimed to evaluate the AST-to-ALT ratio as an incremental predictor of new onset metabolic syndrome in a population-based cohort study. Material and Methods The population-based cohort study included 2276 adults (903 men and 1373 women) aged 40–70 years, who participated from 2005–2008 (baseline) without metabolic syndrome and were followed up from 2008–2011. Metabolic syndrome was defined according to the harmonized definition of metabolic syndrome. Serum concentrations of AST and ALT were determined by enzymatic methods. Results During an average follow-up period of 2.6-years, 395 individuals (17.4%) developed metabolic syndrome. In a multivariable adjusted model, the odds ratio (95% confidence interval) for new onset of metabolic syndrome, comparing the fourth quartile to the first quartile of the AST-to-ALT ratio, was 0.598 (0.422–0.853). The AST-to-ALT ratio also improved the area under the receiver operating characteristic curve (AUC) for predicting new cases of metabolic syndrome (0.715 vs. 0.732, P = 0.004). The net reclassification improvement of prediction models including the AST-to-ALT ratio was 0.23 (95% CI: 0.124–0.337, P<0.001), and the integrated discrimination improvement was 0.0094 (95% CI: 0.0046–0.0143, P<0.001). Conclusions The AST-to-ALT ratio independently predicted the future development of metabolic syndrome and had incremental predictive value for incident metabolic syndrome. PMID:27560931

  3. Influence of Preoperative Serum Aspartate Aminotransferase (AST) Level on the Prognosis of Patients with Non-Small Cell Lung Cancer

    PubMed Central

    Chen, Shu-Lin; Xue, Ning; Wu, Mian-Tao; Chen, Hao; He, Xia; Li, Jian-Pei; Liu, Wan-Li; Dai, Shu-Qin

    2016-01-01

    The purpose of this work is to analyze preoperative serum aspartate aminotransferase (AST) levels and their effect on the prognosis of patients with non-small cell lung cancer (NSCLC) after surgical operation. These analyses were performed retrospectively in patients with NSCLC followed by surgery; participants were recruited between January 2004 and January 2008. All clinical information and laboratory results were collected from medical records. We explored the association between preoperative serum AST and recurrence-free survival (RFS), and the overall survival (OS) of NSCLC patients. Kaplan–Meier analysis and Cox multivariate analysis, stratified by the AST median value, were used to evaluate the prognostic effect. A chi-squared test was performed to compare clinical characteristics in different subgroups. A p-value of ≤0.05 was considered to be statistically significant. A total of 231 patients were enrolled. The median RFS and OS were 22 and 59 months, respectively. The AST levels were divided into two groups, using a cut-off value of 19 U/L: High AST (>19 U/L), n = 113 vs. low AST (≤19 U/L), n = 118. Multivariate analysis indicated that preoperative serum AST > 19 U/L (hazard ratio (HR) = 0.685, 95% confidence interval (CI): 0.493–0.994, p = 0.046 for RFS, HR = 0.646, 95% CI: 0.438–0.954, p = 0.028 for OS) was an independent prognostic factor for both RFS and OS. High preoperative serum AST levels may serve as a valuable marker to predict the prognosis of NSCLC after operation. PMID:27598151

  4. Detection of Carbapenemases in Clinical Enterobacteriaceae Isolates Using the VITEK AST-N202 Card

    PubMed Central

    Bae, Il Kwon; Kang, Hyun-Kyung; Jang, In-Ho; Lee, Woonhyoung; Kim, Keonhan; Jeong, Seok Hoon; Lee, Kyungwon

    2015-01-01

    Background The rapid and accurate detection of carbapenemase-producing Enterobacteriaceae (CPE) in clinical microbiology laboratories is essential for the treatment and control of infections caused by these microorganisms. This study was performed to evaluate the ability of the VITEK AST-N202 card to detect CPE isolates. Materials and Methods A total of 43 (Klebsiella pneumoniae, n = 37; Escherichia coli, n = 3; and Enterobacter cloacae, n = 3) CPE isolates and 79 carbapenemase-non-producing Enterobacteriaceae (CNE) isolates were included in this study. The CPE isolates harbored KPC-2 (n = 11), KPC-3 (n = 20), GES-5 (n = 5), VIM-2 (n = 2), IMP-1 (n = 1), NDM-1 (n = 2), or OXA-232 (n = 2). Of the 79 CNE isolates, eight K. pneumoniae isolates were resistant to ertapenem, imipenem, and meropenem, while the remaining 71 isolates were susceptible to the carbapenems. Antimicrobial susceptibilities were tested using the VITEK AST-N202 card, and the results were interpreted as positive when the isolates showed resistant or intermediate results. Modified-Hodge tests (MHTs) were performed using ertapenem or meropenem disks for the screening of carbapenemase production. Polymerase chain reaction (PCR) and direct sequencing were used to identify β-lactamase genes. Results Sensitivity of MHT with ertapenem and meropenem disks for the detection of carbapenemase was 81.4% (35/43) and 81.4% (35/43), respectively, and a combination with both antibiotic disks increased the sensitivity to 88.4% (38/43). Specificity of the MHT was 100% (79/79) for the CNE isolates. Sensitivity of ertapenem, imipenem, and meropenem as assessed by the VITEK AST-N202 card was 100% (43/43), 93% (40/43), and 95.3% (41/43), respectively. Specificity (89.8%, 71/79) of the test with each carbapenem was improved to 100% (71/71) when eight carbapenem-resistant CNE isolates were excluded from the testing. Conclusion The VITEK AST-N202 card showed high sensitivity for the detection of carbapenemases in

  5. AST: Activity-Security-Trust driven modeling of time varying networks.

    PubMed

    Wang, Jian; Xu, Jiake; Liu, Yanheng; Deng, Weiwen

    2016-02-18

    Network modeling is a flexible mathematical structure that enables to identify statistical regularities and structural principles hidden in complex systems. The majority of recent driving forces in modeling complex networks are originated from activity, in which an activity potential of a time invariant function is introduced to identify agents' interactions and to construct an activity-driven model. However, the new-emerging network evolutions are already deeply coupled with not only the explicit factors (e.g. activity) but also the implicit considerations (e.g. security and trust), so more intrinsic driving forces behind should be integrated into the modeling of time varying networks. The agents undoubtedly seek to build a time-dependent trade-off among activity, security, and trust in generating a new connection to another. Thus, we reasonably propose the Activity-Security-Trust (AST) driven model through synthetically considering the explicit and implicit driving forces (e.g. activity, security, and trust) underlying the decision process. AST-driven model facilitates to more accurately capture highly dynamical network behaviors and figure out the complex evolution process, allowing a profound understanding of the effects of security and trust in driving network evolution, and improving the biases induced by only involving activity representations in analyzing the dynamical processes.

  6. AST: Activity-Security-Trust driven modeling of time varying networks

    PubMed Central

    Wang, Jian; Xu, Jiake; Liu, Yanheng; Deng, Weiwen

    2016-01-01

    Network modeling is a flexible mathematical structure that enables to identify statistical regularities and structural principles hidden in complex systems. The majority of recent driving forces in modeling complex networks are originated from activity, in which an activity potential of a time invariant function is introduced to identify agents’ interactions and to construct an activity-driven model. However, the new-emerging network evolutions are already deeply coupled with not only the explicit factors (e.g. activity) but also the implicit considerations (e.g. security and trust), so more intrinsic driving forces behind should be integrated into the modeling of time varying networks. The agents undoubtedly seek to build a time-dependent trade-off among activity, security, and trust in generating a new connection to another. Thus, we reasonably propose the Activity-Security-Trust (AST) driven model through synthetically considering the explicit and implicit driving forces (e.g. activity, security, and trust) underlying the decision process. AST-driven model facilitates to more accurately capture highly dynamical network behaviors and figure out the complex evolution process, allowing a profound understanding of the effects of security and trust in driving network evolution, and improving the biases induced by only involving activity representations in analyzing the dynamical processes. PMID:26888717

  7. AST: Activity-Security-Trust driven modeling of time varying networks.

    PubMed

    Wang, Jian; Xu, Jiake; Liu, Yanheng; Deng, Weiwen

    2016-01-01

    Network modeling is a flexible mathematical structure that enables to identify statistical regularities and structural principles hidden in complex systems. The majority of recent driving forces in modeling complex networks are originated from activity, in which an activity potential of a time invariant function is introduced to identify agents' interactions and to construct an activity-driven model. However, the new-emerging network evolutions are already deeply coupled with not only the explicit factors (e.g. activity) but also the implicit considerations (e.g. security and trust), so more intrinsic driving forces behind should be integrated into the modeling of time varying networks. The agents undoubtedly seek to build a time-dependent trade-off among activity, security, and trust in generating a new connection to another. Thus, we reasonably propose the Activity-Security-Trust (AST) driven model through synthetically considering the explicit and implicit driving forces (e.g. activity, security, and trust) underlying the decision process. AST-driven model facilitates to more accurately capture highly dynamical network behaviors and figure out the complex evolution process, allowing a profound understanding of the effects of security and trust in driving network evolution, and improving the biases induced by only involving activity representations in analyzing the dynamical processes. PMID:26888717

  8. Agreement among 2 x 2 Agreement Indices.

    ERIC Educational Resources Information Center

    Conger, Anthony J.; Ward, David G.

    1984-01-01

    Sixteen measures of reliability for two-category nominal scales are compared. Upon correcting for chance agreement, there are only five distinct indices: Fleiss's modification of A-sub-1, the phi coefficient, Cohen's kappa, and two intraclass coefficients. Recommendations for choosing an agreement index are made based on definitions, magnitude,…

  9. Advanced Subsonic Technology (AST) 22-Inch Low Noise Research Fan Rig Preliminary Design of ADP-Type Fan 3

    NASA Technical Reports Server (NTRS)

    Jeracki, Robert J. (Technical Monitor); Topol, David A.; Ingram, Clint L.; Larkin, Michael J.; Roche, Charles H.; Thulin, Robert D.

    2004-01-01

    This report presents results of the work completed on the preliminary design of Fan 3 of NASA s 22-inch Fan Low Noise Research project. Fan 3 was intended to build on the experience gained from Fans 1 and 2 by demonstrating noise reduction technology that surpasses 1992 levels by 6 dB. The work was performed as part of NASA s Advanced Subsonic Technology (AST) program. Work on this task was conducted in the areas of CFD code validation, acoustic prediction and validation, rotor parametric studies, and fan exit guide vane (FEGV) studies up to the time when a NASA decision was made to cancel the design, fabrication and testing phases of the work. The scope of the program changed accordingly to concentrate on two subtasks: (1) Rig data analysis and CFD code validation and (2) Fan and FEGV optimization studies. The results of the CFD code validation work showed that this tool predicts 3D flowfield features well from the blade trailing edge to about a chord downstream. The CFD tool loses accuracy as the distance from the trailing edge increases beyond a blade chord. The comparisons of noise predictions to rig test data showed that both the tone noise tool and the broadband noise tool demonstrated reasonable agreement with the data to the degree that these tools can reliably be used for design work. The section on rig airflow and inlet separation analysis describes the method used to determine total fan airflow, shows the good agreement of predicted boundary layer profiles to measured profiles, and shows separation angles of attack ranging from 29.5 to 27deg for the range of airflows tested. The results of the rotor parametric studies were significant in leading to the decision not to pursue a new rotor design for Fan 3 and resulted in recommendations to concentrate efforts on FEGV stator designs. The ensuing parametric study on FEGV designs showed the potential for 8 to 10 EPNdB noise reduction relative to the baseline.

  10. Next challenges for the NEODyS and AstDyS data processing systems

    NASA Astrophysics Data System (ADS)

    Bernardi, Fabrizio

    2015-08-01

    NEODyS and AstDyS are systems that provide asteroid dynamical data through dedicated web services. In particular, NEODyS is devoted to the Near Earth Objects orbital data computations and impact monitoring activities on a hourly basis, while AstDyS computes orbits and dynamical information (such as the asteroid family membership) of all numbered and multi-opposition asteroids on a monthly basis. Both systems are operational for more than 15 years.During the last years the major NEO surveys such as CSS, Pan-STARRS and so on and so forth increased the rate of discovery of new NEOs passing the threshold of 1000 discoveries/year. In particular, in 2014 there was a relative increase of about 42% wtrt 2013, mostly thanks to the full availability of the Pan-STARRS telescope for the NEO survey.In this framework is important to notice that the NEO population characterization is near to be complete for objects brighter that 18th, while the big majority of new discoveries are smaller and smaller objects.The major consequence is that we should expect a higher and higher number of discoveries of the so-called possible imminent impactors, that is small objects (from the Tunguska class and less) which are going to impact the Earth within the next days or hours.It is foreseen that in the next decade new dedicated surveys such as the American ATLAS and the European Fly-Eye telescopes will scan the sky just with the purpose of detecting such possible imminent impactors. The amount of data from the already operative surveys and the new ones will increase dramatically, while the time for processing such amount of data must be necessary shorten than in the past. Moreover, this huge quantity of astrometric data will increase also the knowledge of the dynamics of all known asteroids of the Solar System.In this panel we discuss the next decades new challenges for the NEODyS and AstDyS systems and for the NEO system as a whole. The major players of the NEO system will be the observers

  11. A Metabolomic Approach to Clarifying the Effect of AST-120 on 5/6 Nephrectomized Rats by Capillary Electrophoresis with Mass Spectrometry (CE-MS)

    PubMed Central

    Akiyama, Yasutoshi; Takeuchi, Yoichi; Kikuchi, Koichi; Mishima, Eikan; Yamamoto, Yasuaki; Suzuki, Chitose; Toyohara, Takafumi; Suzuki, Takehiro; Hozawa, Atsushi; Ito, Sadayoshi; Soga, Tomoyoshi; Abe, Takaaki

    2012-01-01

    The oral adsorbent AST-120 is composed of spherical carbon particles and has an adsorption ability for certain small-molecular-weight compounds that accumulate in patients with chronic kidney disease (CKD). So far, very few compounds are known to be adsorbed by AST-120 in vivo. To examine the effect of AST-120 in vivo, we comprehensively evaluated the plasma concentrations of 146 compounds (61 anions and 85 cations) in CKD model rats, with or without four weeks of treatment with AST-120. By capillary electrophoresis with mass spectrometry, we identified 6 anions and 17 cations that were significantly decreased by AST-120 treatment. In contrast, we also identified 2 cations that were significantly increased by AST-120. Among them, 4 anions, apart from indoxyl sulfate and hippurate, and 19 cations were newly identified in this study. The plasma levels of N-acetyl-neuraminate, 4-pyridoxate, 4-oxopentanoate, glycine, γ-guanidinobutyrate, N-γ-ethylglutamine, allantoin, cytosine, 5-methylcytosine and imidazole-4-acetate were significantly increased in the CKD model compared with the sham-operated group, and were significantly decreased by AST-120 treatment. Therefore, these 10 compounds could be added as uremic compounds that indicate the effect of AST-120 treatment. This study provides useful information not only for identifying the indicators of AST-120, but also for clarifying changes in the metabolic profile by AST-120 treatment in the clinical setting. PMID:23202318

  12. Characterization of (As.Te)1-xSex thin films

    NASA Astrophysics Data System (ADS)

    Hafiz, M. M.; Moharram, A. H.; Abu-Sehly, A. A.

    Optical absorption at room temperature and electrical resistivity at temperatures between 200 and 320 K for (As.Te)1-xSex thin films (where x=0.20, 0.23, 0.27, 0.32 and 0.44) have been studied. Increasing the Se content was found to increase the optical energy gap and the activation energy for conduction of the investigated films. The optical energy gap of the As0.40Te0.40Se0.20 films was increased up to 1.21 eV by increasing the film thickness to 120 nm, while thermal annealing at 480 K reduced it down to 0.83 eV. The decrease of the optical gap is discussed on the basis of amorphous-crystalline transformations.

  13. Distribution of C-type allatostatin (C-AST)-like immunoreactivity in the central nervous system of the copepod Calanus finmarchicus

    PubMed Central

    Wilson, Caroline H.; Christie, Andrew E.

    2010-01-01

    The C-type Allatostatins (C-ASTs) are a family of highly pleiotropic arthropod neuropeptides. In crustaceans, transcriptomic/mass spectral studies have identified C-ASTs in the nervous systems of many species; the cellular distributions of these peptides remain unknown. Here, the distribution of C-AST was mapped in the nervous system of the copepod Calanus finmarchicus, the major contributor to the North Atlantic’s zooplanktonic biomass; C-AST-immunopositive neurons were identified in the protocerebrum, in several peripheral ganglia associated with feeding appendages, and in the ganglia controlling the swimming legs, with immunopositive axons present throughout the ventral nerve cord. In addition, axons innervating the dorsal longitudinal and ventral longitudinal muscles of the body wall of the metasome were labeled by the C-AST antibody. While the distribution of C-AST-like immunoreactivity was similar between sexes, several differences were noted, i.e. two pair of somata located at the deutocerebral/tritocerbral border in males and immunopositive fibers that surround the genital opening in females. To place the C-AST-like labeling into context with those of several previously mapped peptides, i.e. A-type allatostatin (A-AST) and tachykinin-related peptide (TRP), we conducted double-labeling studies; the C-AST-like immunopositive neurons appear distinct from those expressing either A-AST or TRP (and through extrapolation, pigment dispersing hormone). Collectively, our data represent the first mapping of C-AST in crustacean neural tissue, show that sex-specific differences in the distribution of C-AST exist in the C. finmarchicus CNS, and suggest that the peptide may be involved in the modulation of both feeding and postural control/locomotion. PMID:20338176

  14. Exact partition functions for the Ω-deformed {N}={2}^{ast } SU(2) gauge theory

    NASA Astrophysics Data System (ADS)

    Beccaria, Matteo; Macorini, Guido

    2016-07-01

    We study the low energy effective action of the Ω-deformed {N}={2}^{ast } SU(2) gauge theory. It depends on the deformation parameters ɛ 1, ɛ 2, the scalar field expectation value a, and the hypermultiplet mass m. We explore the plane (m/ɛ_1,ɛ_2/ɛ_1) looking for special features in the multi-instanton contributions to the prepotential, motivated by what happens in the Nekrasov-Shatashvili limit ɛ 2 → 0. We propose a simple condition on the structure of poles of the k-instanton prepotential and show that it is admissible at a finite set of points in the above plane. At these special points, the prepotential has poles at fixed positions independent on the instanton number. Besides and remarkably, both the instanton partition function and the full prepotential, including the perturbative contribution, may be given in closed form as functions of the scalar expectation value a and the modular parameter q appearing in special combinations of Eisenstein series and Dedekind η function. As a byproduct, the modular anomaly equation can be tested at all orders at these points. We discuss these special features from the point of view of the AGT correspondence and provide explicit toroidal 1-blocks in non-trivial closed form. The full list of solutions with 1, 2, 3, and 4 poles is determined and described in details.

  15. Test and Commissioning of the AST3-1 Control System

    NASA Astrophysics Data System (ADS)

    Li, Xiaoyan; Wang, Daxing

    2013-01-01

    The first of three Antarctic Survey Telescopes (AST3-1), a 50/68cm Schmidt-like equatorial-mount telescope, is the first trackable Chinese telescope operating on the Antarctic plateau. It was installed at Dome A (80°22', 77°21'E, 4,093m), the highest place on the Antarctic plateau, in 2012. The telescope is unmanned during night-time operations through the Austral winter. The telescope optics and mechanics, as well as the motors and position sensors, are exposed to a harsh environment. The mechanics is enclosed with a foldable tent-like dome to prevent snow, diamond dust and ice. While the control cabinet containing drive boxes, circuit board boxes, power converters and the Telescope Control Computer (TCC) is located inside the warm instrumental module. In about 15 weeks remote testing and commissioning, from January 24 when the expedition team left there to May 8, when the communication failed, we obtained images with the best FWHM of less than 2''. We also recorded the telescope movement performance and fine-tuned the dynamic properties of the telescope control system. Some experiences and lessons will be disscussed in this paper.

  16. A European Roadmap for Research in Astrobiology - The AstRoMap Roadmap

    NASA Astrophysics Data System (ADS)

    Gómez, F.; Walter, N.; Horneck, G.; Muller, C.; Rettberg, P.; Capria, M.; Palomba, E.

    2015-10-01

    AstRoMap (Astrobiology Road Mapping activity-www.astromap-eu.org) is a collaborative project which will provide the European Planetary Science Community with a road map in astrobiology. The goals of the project have been: (i) to pose big questions related to astrobiology; and (ii) the identification of experiments, new technology and/or those space missions to be developed in future programs and which could answer those big questions. This collaborative infrastructure includes the organization of expert panels and international workshops in order to discuss about those big questions and the science objectives by the community to be addressed. The main deliverable will be a Roadmap document. The project is steered by a consortium of six European and national research institutes and associations: -­- Centro de Astrobiologica (INTACSIC), Spain -­- European Science Foundation, France -­- Association pour un Réseau Européen d'Exo/Astrobiology (EANA), France -­- B-USOC, Belgium -­- Deutsches Zentrum für Luft- und Raumfahrt (DLR), Germany -­- National Institute for Astrophysics (INAF), ItalyOrigin and evolution of planetary systems -­- Origin of organic compounds in space -­- Rock-water-carbon interactions, organic synthesis, and steps to life -­- Life and habitability on Earth and in Space -­- -­- Biosignatures as facilitating life detection The key topics will focus on a limited number of strategic scientific objectives to be addressed in the next 20 years by European astrobiologists, and suggest research activities for future development.

  17. Agreement, Shells, and Focus.

    ERIC Educational Resources Information Center

    Simpson, Andrew; Wu, Zoe

    2002-01-01

    Reconsiders development and licensing of agreement as a syntactic projection and argues for a productive developmental relation between agreement and the category of focus. Suggests that focus projections are initially selected by a variety of functional heads with real semantic content, then, over time decays into a simple concord shell. Upon…

  18. Non-Proliferation Agreements.

    ERIC Educational Resources Information Center

    Swalec, John J.

    1981-01-01

    Discusses five kinds of cooperative agreements established by the College of Lake County (IL): those with other community colleges/technical institutes; the military; business, industry, and organizations; secondary schools; and community and special interest groups. Pays particular attention to two kinds of agreements with other colleges. (CAM)

  19. Cooperative Agreements Study Report.

    ERIC Educational Resources Information Center

    Lawton, R. E.; Magruder, D.

    During the 1983 meeting of the Florida Legislature, action was taken to begin a systematic study of the level of cooperation between the Florida public schools K-12 program and the community and junior colleges. The goals and objectives of the Cooperative Agreements Study were to review and compile a list of the cooperative agreements and identify…

  20. The Helsinki Agreement

    ERIC Educational Resources Information Center

    Babel: Journal of the Australian Federation of Modern Language Teachers' Associations, 1977

    1977-01-01

    A reprint of sections of the Helsinki agreement dealing with foreign languages and civilization, and cooperation and exchanges in the field of education. The agreement supports wider knowledge of foreign languages and promotes exchanges, cooperation, lexicography, and specialized programs in adult education. (AMH)

  1. Suicide inactivation of rat liver aryl sulfotransferase IV (AST IV) by the sulfuric acid ester of N-hydroxy-2-acetylaminofluorene (NOH-AAF)

    SciTech Connect

    Ringer, D.P.; Norton, T.R.; Self, R.R. )

    1991-03-11

    Rat liver NOH-AAf sulfotransferase activity is mediated by AST IV and causes the bioactivation of NOH-AAF to a highly reactive, mutagenic sulfuric acid ester form which putatively has a role in inducing liver cancer. Unexpectedly, AAF has been found to decrease liver NOH-AAF sulfotransferase activity in dietary protocols used to induce hepatocarcinogenesis. The authors have thus examined reaction-product, suicide inactivation of AST IV as a possible mechanism for the loss in sulfotransferase activity. In initial experiments, purified AST IV was found to undergo a PAPS-dependent binding with ({sup 14}C)-NOH-AAF. Alkaline hydrolysis and C18-HPLC analysis of the AST IV:AAF conjugates revealed that linkage primarily involved cysteine and methionine residues of AST IV. Experiments testing the effect of pretreatment of AST IV with NOH-AAF upon subsequent assay of sulfotransferase activity, showed that there was a NOH-AAF and PAPS dependent loss in AST IV sulfotransferase activity. These results demonstrate the highly reactive, sulfuric acid ester of NOH-AAF can covalently link with AST IV causing suicide inactivation of the enzyme, and suggests that it deserves consideration as an in vivo mechanism for loss of NOH-AAF sulfotransferase activity.

  2. Astrobiology Road Mapping (AstRoMap) - A project within FP7 of the European Commission: First results

    NASA Astrophysics Data System (ADS)

    Gomez-Gomez, Felipe; Capria, Maria Teresa; Palomba, Ernesto; Walter, Nicolas; Rettberg, Petra; Muller, Christian; Horneck, Gerda

    AstRoMap (Astrobiology and Planetary Exploration Road Mapping) is a funded project formulated in the 5th Call of the European Commission FP7 framework. The main objectives of the AstRoMap are: 1. Identify the main astrobiology issues to be addressed by Europe in the next decades in relation with space exploration 2. Identify potential mission concepts that would allow addressing these issues 3. Identify the technology developments required to enable these missions 4. Provide a prioritized roadmap integrating science and technology activities as well as ground-based approach 5. Map scientific knowledge related to astrobiology in Europe To reach those objectives, AstRoMap is executed within the following steps: 1. Community consultation. In order to map the European astrobiology landscape and to provide a collaborative networking platform for this community, the AstRoMap project hosts a database of scientists (European and beyond) interested in astrobiology and planetary exploration (see: http://www.astromap.eu/database.html). It reflects the demography and the research and teaching activities of the astrobiology community, as well as their professional profiles and involvement in astrobiology projects. Considering future aspects of astrobiology in Europe, the need for more astrobiology-dedicated funding programmes at the EU level, especially for cross-disciplinary groups, was stressed. This might eventually lead to the creation of a European laboratory of Astrobiology, or even of a European Astrobiology Institute. 2. Workshops organisation. On the basis of the feedbacks from the community consultation, the potential participants and interesting topics are being identified to take part in the following workshops: 1-. Origin of organic compounds, steps to life; 2. Physico-chemical boundary conditions for habitability 3. Biosignatures as facilitating life detection 4. Origin of the Solar system 3. Astrobiology road-mapping. Based on the results and major conclusions

  3. Conceptual study of an advanced supersonic technology transport (AST-107) for transpacific range using low-bypass-ratio turbofan engines

    NASA Technical Reports Server (NTRS)

    Morris, S. J., Jr.; Foss, W. E., Jr.; Neubauer, M. J., Jr.

    1980-01-01

    An advanced supersonic technology configuration concept designated the AST-107, using a low bypass ratio turbofan engine, is described and analyzed. The aircraft had provisions for 273 passengers arranged five abreast. The cruise Mach number was 2.62. The mission range for the AST-107 was 8.48 Mm (4576 n.mi.) and an average lift drag ratio of 9.15 during cruise was achieved. The available lateral control was not sufficient for the required 15.4 m/s (30 kt) crosswind landing condition, and a crosswind landing gear or a significant reduction in dihedral effect would be necessary to meet this requirement. The lowest computed noise levels, including a mechanical suppressor noise reduction of 3 EPNdB at the flyover and sideline monitoring stations, were 110.3 EPNdB (sideline noise), 113.1 EPNdB (centerline noise) and 110.5 EPNdB (approach noise).

  4. Continuous Reduction of Protein-Bound Uraemic Toxins with Improved Oxidative Stress by Using the Oral Charcoal Adsorbent AST-120 in Haemodialysis Patients.

    PubMed

    Yamamoto, Suguru; Kazama, Junichiro J; Omori, Kentaro; Matsuo, Koji; Takahashi, Yoshimitsu; Kawamura, Kazuko; Matsuto, Takayuki; Watanabe, Hiroshi; Maruyama, Toru; Narita, Ichiei

    2015-09-23

    Accumulation of protein-bound uraemic toxins (PBUTs) is one of the reasons for the development of uraemia-related complications including cardiovascular disease; however, conventional haemodialysis is limited in its ability to remove PBUTs. We aimed to examine whether the oral charcoal adsorbent AST-120 has an additive effect on PBUT removal in haemodialysis patients. During the 4-week study, anuric patients undergoing haemodialysis received AST-120 (6 g/day) in the last 2 weeks (n = 10) or the first 2 weeks (n = 10). Serum levels of total and free PBUTs such as indoxyl sulfate, p-cresyl sulfate, and phenyl sulfate at the pre- and postdialysis sessions were measured before and after AST-120 use and after discontinuation. Levels of the oxidative stress markers oxidized albumin and 8-isoprostane were also measured. AST-120 use induced dramatic reduction of indoxyl sulfate (total, 45.7% [33.2-50.5%]; free, 70.4% [44.8-79.8%]), p-cresyl sulfate (total, 31.1% [25.0-48.0%]; free, 63.5% [49.3-70.9%]), and phenyl sulfate (free, 50.6% [32.3-71.2%]) levels; however, this effect disappeared after the discontinuation of AST-120. AST-120 use also induced substantial reduction of the oxidized albumin and 8-isoprostane levels. In conclusion, oral administration of AST-120 had additive effects on the continuous reduction of some PBUTs in anuric patients undergoing haemodialysis.

  5. FFTF Authorization Agreement

    SciTech Connect

    DAUTEL, W.A.

    2000-09-25

    The purpose of the Authorization Agreement is to serve as a mechanism whereby the U.S. Department of Energy, Richland Operations Office (RL) and Fluor Hanford (FH) jointly clarify and agree to key conditions for conducting work safely and efficiently in the Fast Flux Test Facility (FFTF). Work must be accomplished in a manner that achieves high levels of quality while protecting the environment and the safety and health of workers and the public, and complying with applicable contractual and regulatory requirements. It is the intent of this Agreement to address those items of significant importance in establishing and supporting the FFTF Authorization Envelope, but this Agreement in no way alters the terms and conditions of the Project Hanford Management Contract (PHMC), Contract Number DE-AC06-96RL13200.

  6. Agreements in Virtual Organizations

    NASA Astrophysics Data System (ADS)

    Pankowska, Malgorzata

    This chapter is an attempt to explain the important impact that contract theory delivers with respect to the concept of virtual organization. The author believes that not enough research has been conducted in order to transfer theoretical foundations for networking to the phenomena of virtual organizations and open autonomic computing environment to ensure the controllability and management of them. The main research problem of this chapter is to explain the significance of agreements for virtual organizations governance. The first part of this chapter comprises explanations of differences among virtual machines and virtual organizations for further descriptions of the significance of the first ones to the development of the second. Next, the virtual organization development tendencies are presented and problems of IT governance in highly distributed organizational environment are discussed. The last part of this chapter covers analysis of contracts and agreements management for governance in open computing environments.

  7. Countries renew rescue agreement

    NASA Astrophysics Data System (ADS)

    Bush, Susan M.

    To insure long-term continuity for the international satellite search and rescue system, COSPAS/SARSAT, an intergovernmental agreement binding the four sponsoring nations to cooperate was signed July 1 in Paris. According to Russell Vollmers of the National Oceanic and Atmospheric Administration, the agreement is binding for 15 years, with an automatic extension.The system marked the fifth anniversary of its first rescue last year, when on September 10, 1982, three persons were rescued. Begun in the 1970s by NASA as an experiment, COSPAS/SARSAT (a Russian-English acronym) is now a cooperative project among the United States, Canada, France, and the Soviet Union. Its goal is to reduce the time required to rescue air and maritime distress victims and also to locate victims who otherwise may not be found, thus using the satellite system as a life-saving device.

  8. Evaluation of the Effect of Passive Smoking on Lactoferrin and AST on 12 - 15 Years Old Children and Adolescents

    PubMed Central

    Jenabian, Niloofar; Pouramir, Mahdi; Motallebnejad, Mina; Bamdadian, Jale; Rahimi-Rad, Morteza

    2015-01-01

    Background: Passive smokers are involuntarily exposed to cigarette or tobacco smoke and as known, inhalation of environmental tobacco smoke is a serious threat. There is little information about the effect of passive smoking on salivary markers and periodontal indices. Objectives: This study investigated the effect of passive smoking on lactoferrin and AST in 12 - 15 years old children and adolescents. Patients and Methods: This case-control analytic correlation type study with no-convenience random sampling method was performed on 160 children aged 12 - 15 who had smokers in their families. The eligible children were divided into two equal groups; 80 cot+ children as case group and 80 cot– children as control group, matched according to age, sex and plaque index. Plaque index was obtained from all subjects. 2 cc unstimulated salivary samples were collected by spitting method. The collected specimens were tested by lactoferrin and AST kits in biochemistry were measured on the day of sampling laboratory. Gingival index Loe and Silness (GI) and Probing Pocket Depth (PPD). Results: Mean and Standard Deviation of PPD and GI was 2.01 ± 0.077 and 1.53 ± 0.055 in experimental group and 1.93 ± 0.073 and 1.49 ± 0.046 in control group respectively (P < 0.001). The Mean and Standard Deviation parameters of lactoferrin and AST, in the experimental group was 38.66 ± 25.15 and 13.45 ± 6.33 and in the control group 10.18 ± 6.82 and 6.53 ± 2.65 group, respectively (P < 0.001). Conclusions: Passive smoking can be effective on inflammatory process of periodontal and salivary biomarkers related to inflammation. Lactoferrin was 11 - 104 in case group and 0.5 - 38 in control group. Aspartat aminotransferase in case group was 2.64 - 30.43 and in control group it was 2.16 - 12.02. PMID:26495095

  9. Advanced Subsonic Technology (AST) Area of Interest (AOI) 6: Develop and Validate Aeroelastic Codes for Turbomachinery

    NASA Technical Reports Server (NTRS)

    Gardner, Kevin D.; Liu, Jong-Shang; Murthy, Durbha V.; Kruse, Marlin J.; James, Darrell

    1999-01-01

    AlliedSignal Engines, in cooperation with NASA GRC (National Aeronautics and Space Administration Glenn Research Center), completed an evaluation of recently-developed aeroelastic computer codes using test cases from the AlliedSignal Engines fan blisk and turbine databases. Test data included strain gage, performance, and steady-state pressure information obtained for conditions where synchronous or flutter vibratory conditions were found to occur. Aeroelastic codes evaluated included quasi 3-D UNSFLO (MIT Developed/AE Modified, Quasi 3-D Aeroelastic Computer Code), 2-D FREPS (NASA-Developed Forced Response Prediction System Aeroelastic Computer Code), and 3-D TURBO-AE (NASA/Mississippi State University Developed 3-D Aeroelastic Computer Code). Unsteady pressure predictions for the turbine test case were used to evaluate the forced response prediction capabilities of each of the three aeroelastic codes. Additionally, one of the fan flutter cases was evaluated using TURBO-AE. The UNSFLO and FREPS evaluation predictions showed good agreement with the experimental test data trends, but quantitative improvements are needed. UNSFLO over-predicted turbine blade response reductions, while FREPS under-predicted them. The inviscid TURBO-AE turbine analysis predicted no discernible blade response reduction, indicating the necessity of including viscous effects for this test case. For the TURBO-AE fan blisk test case, significant effort was expended getting the viscous version of the code to give converged steady flow solutions for the transonic flow conditions. Once converged, the steady solutions provided an excellent match with test data and the calibrated DAWES (AlliedSignal 3-D Viscous Steady Flow CFD Solver). However, efforts expended establishing quality steady-state solutions prevented exercising the unsteady portion of the TURBO-AE code during the present program. AlliedSignal recommends that unsteady pressure measurement data be obtained for both test cases examined

  10. PhyloToAST: Bioinformatics tools for species-level analysis and visualization of complex microbial datasets.

    PubMed

    Dabdoub, Shareef M; Fellows, Megan L; Paropkari, Akshay D; Mason, Matthew R; Huja, Sarandeep S; Tsigarida, Alexandra A; Kumar, Purnima S

    2016-01-01

    The 16S rRNA gene is widely used for taxonomic profiling of microbial ecosystems; and recent advances in sequencing chemistry have allowed extremely large numbers of sequences to be generated from minimal amounts of biological samples. Analysis speed and resolution of data to species-level taxa are two important factors in large-scale explorations of complex microbiomes using 16S sequencing. We present here new software, Phylogenetic Tools for Analysis of Species-level Taxa (PhyloToAST), that completely integrates with the QIIME pipeline to improve analysis speed, reduce primer bias (requiring two sequencing primers), enhance species-level analysis, and add new visualization tools. The code is free and open source, and can be accessed at http://phylotoast.org. PMID:27357721

  11. Optics characterization of a 900-GHz HEB receiver for the ASTE telescope: design, measurement and tolerance analysis

    NASA Astrophysics Data System (ADS)

    Gonzalez, A.; Soma, T.; Shiino, T.; Kaneko, K.; Uzawa, Y.; Yamamoto, S.

    2014-09-01

    The optics of a 900-GHz HEB receiver for the ASTE telescope have been analyzed by quasi-optical analysis and Physical Optics simulations in combination with beam pattern measurements. The disagreement between simulations and measurements has motivated an extensive campaign of Monte Carlo analyses to find out the cause of such a difference in results. Monte Carlo analyses have considered fabrication and assembly tolerances in all components in the RF chain, as well as some non-expected fabrication errors. This strategy has allowed determining the defective component. In short, the use of all available analyses techniques together with measurements has allowed singling out an underperforming element in an astronomical receiver. The change of this component will improve the optical efficiency and ease astronomical observations. These ideas can be of interest for any quasi-optical receiver at THz frequencies.

  12. PhyloToAST: Bioinformatics tools for species-level analysis and visualization of complex microbial datasets

    PubMed Central

    Dabdoub, Shareef M.; Fellows, Megan L.; Paropkari, Akshay D.; Mason, Matthew R.; Huja, Sarandeep S.; Tsigarida, Alexandra A.; Kumar, Purnima S.

    2016-01-01

    The 16S rRNA gene is widely used for taxonomic profiling of microbial ecosystems; and recent advances in sequencing chemistry have allowed extremely large numbers of sequences to be generated from minimal amounts of biological samples. Analysis speed and resolution of data to species-level taxa are two important factors in large-scale explorations of complex microbiomes using 16S sequencing. We present here new software, Phylogenetic Tools for Analysis of Species-level Taxa (PhyloToAST), that completely integrates with the QIIME pipeline to improve analysis speed, reduce primer bias (requiring two sequencing primers), enhance species-level analysis, and add new visualization tools. The code is free and open source, and can be accessed at http://phylotoast.org. PMID:27357721

  13. AST to Platelet Index Correlates with Hepatic Cirrhosis But Not with Fibrosis in Pediatric Patients with Intestinal Failure

    PubMed Central

    Díaz, Juan J; Gura, Kathleen M.; Roda, Juliamna; Perez-Atayde, Antonio R.; Duggan, Christopher; Jaksic, Tom; Lo, Clifford W.

    2013-01-01

    Patients with Intestinal failure (IF) require parenteral nutrition (PN) support to obtain enough nutrients to sustain growth. long-term PN use is associated with significant liver damage. Objective To analyze the utility of a non-invasive test, the aspartate aminotransferase (AST) to platelet ratio index (APRI), in the diagnosis of liver disease in pediatric patients with IF. Methods Medical records of all Boston Children’s Hospital patients who received PN and underwent a liver biopsy from January 2006 until November 2010 were reviewed. Patients with a clinical diagnosis with IF were selected. APRI was calculated as follows (AST (U/L)/ upper normal limit) × 100/ platelets (109/L). Presence of fibrosis and cirrhosis was estimated using the METAVIR score in liver biopsies. Results 62 liver biopsies from 48 patients (22 female) were studied. Mean APRI values in the different METAVIR categories (0-1; 2-3; 4) were: 1.80, 1.17, and 4.24 respectively (ANOVA; P=0.053; Bonferroni test for cirrhosis versus fibrosis P=0.048). APRI could significantly predict cirrhosis (OR 1.2.; 95% CI 1.001-1.43) but not significant fibrosis (METAVIR 2-3, OR 1.00; 95% CI =0.86-1.18). Area under the receiver operating characteristic curve for cirrhosis was 0.67 (95% CI= 0.45-0.89; p=0.13). Conclusion APRI, a non invasive, easy to obtain bedside test significantly predicts cirrhosis but not fibrosis in pediatric patients with IFALD. As the clinicians need a non invasive test to differentiate among different stages of liver fibrosis rather than differentiating cirrhosis from normal, we cannot recommend the use of this test in pediatric patients with IFALD for this purpose. PMID:23666459

  14. Assessment of pharmacogenomic agreement.

    PubMed

    Safikhani, Zhaleh; El-Hachem, Nehme; Quevedo, Rene; Smirnov, Petr; Goldenberg, Anna; Juul Birkbak, Nicolai; Mason, Christopher; Hatzis, Christos; Shi, Leming; Aerts, Hugo Jwl; Quackenbush, John; Haibe-Kains, Benjamin

    2016-01-01

    In 2013 we published an analysis demonstrating that drug response data and gene-drug associations reported in two independent large-scale pharmacogenomic screens, Genomics of Drug Sensitivity in Cancer (GDSC) and Cancer Cell Line Encyclopedia (CCLE), were inconsistent. The GDSC and CCLE investigators recently reported that their respective studies exhibit reasonable agreement and yield similar molecular predictors of drug response, seemingly contradicting our previous findings. Reanalyzing the authors' published methods and results, we found that their analysis failed to account for variability in the genomic data and more importantly compared different drug sensitivity measures from each study, which substantially deviate from our more stringent consistency assessment. Our comparison of the most updated genomic and pharmacological data from the GDSC and CCLE confirms our published findings that the measures of drug response reported by these two groups are not consistent. We believe that a principled approach to assess the reproducibility of drug sensitivity predictors is necessary before envisioning their translation into clinical settings. PMID:27408686

  15. Assessment of pharmacogenomic agreement

    PubMed Central

    Safikhani, Zhaleh; El-Hachem, Nehme; Quevedo, Rene; Smirnov, Petr; Goldenberg, Anna; Juul Birkbak, Nicolai; Mason, Christopher; Hatzis, Christos; Shi, Leming; Aerts, Hugo JWL; Quackenbush, John; Haibe-Kains, Benjamin

    2016-01-01

    In 2013 we published an analysis demonstrating that drug response data and gene-drug associations reported in two independent large-scale pharmacogenomic screens, Genomics of Drug Sensitivity in Cancer (GDSC) and Cancer Cell Line Encyclopedia (CCLE), were inconsistent. The GDSC and CCLE investigators recently reported that their respective studies exhibit reasonable agreement and yield similar molecular predictors of drug response, seemingly contradicting our previous findings. Reanalyzing the authors’ published methods and results, we found that their analysis failed to account for variability in the genomic data and more importantly compared different drug sensitivity measures from each study, which substantially deviate from our more stringent consistency assessment. Our comparison of the most updated genomic and pharmacological data from the GDSC and CCLE confirms our published findings that the measures of drug response reported by these two groups are not consistent. We believe that a principled approach to assess the reproducibility of drug sensitivity predictors is necessary before envisioning their translation into clinical settings. PMID:27408686

  16. Agreement with Subjects in Lubukusu

    ERIC Educational Resources Information Center

    Diercks, Michael J. K.

    2010-01-01

    This dissertation examines three topics in the morphosyntax of Lubukusu (Bantu, Kenya), all of which are concerned with agreement with subjects: locative inversion, complementizer agreement, and alternative agreement effects in subject extraction. Each topic reports novel Lubukusu data which are both typologically interesting and theoretically…

  17. Mining Agreements with Indian Tribes

    ERIC Educational Resources Information Center

    Luebben, Tom

    1976-01-01

    The article discusses aspects of negotiating agreements for exploration, development, and mining of hard minerals on Indian Reservations. The agreements discussed are typical of copper agreements, but the general points under discussion are applicable to most hard minerals except for uranium, coal, and oil which are substantially different.…

  18. Characteristics of the advanced supersonic technology AST-105-1 configured for transpacific range with Pratt and Whitney aircraft variable stream control engines

    NASA Technical Reports Server (NTRS)

    Baber, H. T., Jr.

    1979-01-01

    Credence to systems weights and assurance that the noise study AST concept can be balanced were studied. Current titanium structural technology is assumed. A duct-burning turbofan variable stream control engine (VSCE), with noise reduction potential through use of a coannular nozzle was used. With 273 passengers, range of the AST-105-1 for a cruise Mach number of 2.62 is essentially transpacific. Lift-to-drag ratio is slightly higher than for previous AST configurations. It is trimmable over a center-of-gravity range of 4.7m (15.5 ft). Inherent high positive effective dihedral, typical of arrow-wing configurations in high-lift approach, would limit AST-105-1 to operating in crosswinds of 11.6 m/sec (22.4 kt), or less, with 75 percent of available lateral control. Normal power takeoff with cutback results in noise in excess of Federal Aviation Regulation Part 36 but less than for conventional procedure takeoff. Results of advanced (noncertificated) programmed throttle takeoff and approach procedures, not yet optimized, indicate that such can be an important additional method noise reduction.

  19. Wide-field Imaging Survey of Dust Continuum Emissions at lambda = 1.1 mm toward the Chamaeleon and Lupus Regions with AzTEC on ASTE

    SciTech Connect

    Momose, Munetake; Hiramatsu, Masaaki; Tsukagoshi, Takashi; Shimajiri, Yoshito; Ezawa, Hajime; Kawabe, Ryohei; Ikeda, Norio; Kitamura, Yoshimi; Kamegai, Kazuhisa; Saito, Masao

    2009-08-05

    We carried out an imaging survey of dust continuum emissions toward the Chamaeleon and Lupus regions. Observations were made with the 144-element bolometer array camera AzTEC mounted on the 10-meter sub-millimeter telescope ASTE during 2007-2008. The preliminary results of disk search and the cloud structure of Lupus III are presented.

  20. 75 FR 40837 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-14

    ....gov . Agreement No.: 011279-027. Title: Latin America Agreement. Parties: ABC Discussion Agreement; Caribbean Shipowners Association; Central America Discussion Agreement; Compania Libra de Navegacion Uruguay... America Discussion Agreement; and Zim Integrated Shipping Services, Ltd. Filing Party: Wayne R. Rohde,...

  1. Byzantine agreement method without authentication

    SciTech Connect

    Reischuk, R.K.

    1983-12-01

    This invention relates to a method for achieving Byzantine agreement without authentication among n 100 communicating processors using event counting and thresholding rather than message exchanges and evaluations.

  2. Experience and grammatical agreement: Statistical learning shapes number agreement production

    PubMed Central

    Haskell, Todd R.; Thornton, Robert; MacDonald, Maryellen C.

    2009-01-01

    A robust result in research on the production of grammatical agreement is that speakers are more likely to produce an erroneous verb with phrases such as the key to the cabinets, with a singular noun followed by a plural one, than with phrases such as the keys to the cabinet, where a plural noun is followed by a singular. These asymmetries are thought to reflect core language production processes. Previous accounts have attributed error patterns to a syntactic number feature present on plurals but not singulars. An alternative approach is presented in which a process similar to structural priming contributes to the error asymmetry via speakers' past experiences with related agreement constructions. A corpus analysis and two agreement production studies test this account. The results suggest that agreement production is shaped by statistical learning from past language experience. Implications for accounts of agreement are discussed. PMID:19942213

  3. Skills agreement. Recipe for success.

    PubMed

    Nolan, Alexis

    2007-06-21

    The aims of the national health Sector Skills Agreement need regional and local implementation by stakeholders to become reality. Work in the East of England will produce a first regional skills agreement later this year. The Harlow Project is producing award winning process on recuitment and retention. PMID:17847967

  4. AST Launch Vehicle Acoustics

    NASA Technical Reports Server (NTRS)

    Houston, Janice; Counter, D.; Giacomoni, D.

    2015-01-01

    The liftoff phase induces acoustic loading over a broad frequency range for a launch vehicle. These external acoustic environments are then used in the prediction of internal vibration responses of the vehicle and components which result in the qualification levels. Thus, predicting these liftoff acoustic (LOA) environments is critical to the design requirements of any launch vehicle. If there is a significant amount of uncertainty in the predictions or if acoustic mitigation options must be implemented, a subscale acoustic test is a feasible pre-launch test option to verify the LOA environments. The NASA Space Launch System (SLS) program initiated the Scale Model Acoustic Test (SMAT) to verify the predicted SLS LOA environments and to determine the acoustic reduction with an above deck water sound suppression system. The SMAT was conducted at Marshall Space Flight Center and the test article included a 5% scale SLS vehicle model, tower and Mobile Launcher. Acoustic and pressure data were measured by approximately 250 instruments. The SMAT liftoff acoustic results are presented, findings are discussed and a comparison is shown to the Ares I Scale Model Acoustic Test (ASMAT) results.

  5. Federal Facility Agreement progress report

    SciTech Connect

    Not Available

    1993-10-01

    The (SRS) Federal Facility Agreement (FFA) was made effective by the US. Environmental Protection Agency Region IV (EPA) on August 16, 1993. To meet the reporting requirements in Section XXV of the Agreement, the FFA Progress Report was developed. The FFA Progress Report is the first of a series of quarterly progress reports to be prepared by the SRS. As such this report describes the information and action taken to September 30, 1993 on the SRS units identified for investigation and remediation in the Agreement. This includes; rubble pits, runoff basins, retention basin, seepage basin, burning pits, H-Area Tank 16, and spill areas.

  6. Suspension agreements: The status quota

    SciTech Connect

    1996-01-01

    Since the initial filing of anti-dumping actions uranium imports from the former Soviet Union, a maze of filings, agreements, amendments, bills, measures, and deals have emerged on which only the closest observers remain current. Even with all the actions that have taken place, none of the parties appear content with the status quo and changes to the agreements are ongoing. Given this dynamic state of affairs, a recap of events and a summary of the current agreements is helpful for understanding the concerns of the involved parties and digesting future events.

  7. Spectral Line Survey toward RCrA IRS7B in the 345 GHz Window with ASTE

    NASA Astrophysics Data System (ADS)

    Watanabe, Y.; Sakai, N.; Lindberg, J.; Jorgensen, J.; Bisschopi, S.; Yamamoto, S.

    2011-05-01

    Recently, it has been pointed out that the chemical composition in the low-mass protostars varies from source to source. Two extreme cases are the hot corinos where various complex organic molecules are abundant, and the WCCC (Warm Carbon-Chain Chemistry) sources where carbon-chain molecules are abundant. Understanding an origin of such chemical diversity is an important target for astrochemistry. We have conducted a spectral line survey in the 332 - 364 GHz band (figure 1) with ASTE toward a low mass class 0 protostar in the Corona Australis (R CrA IRS7B), which have been recognized as a hot corino candidate because of its bright emissions of H_2CO and CH_3OH. We have also performed a supplementary observations in the 450 GHz band. In total, 16 molecular species including CO, CS, CN, NO, CCH, c-C3H2, HCO+, H2CO and CH3OH are identified. Strong emissions of CN, and CCH are observed, whereas, complex organic molecules and long carbon-chain molecules were not detected. The rotation temperature of CH3OH is evaluated to be ˜ 16 K, which is much lower than that in the typical hot corino IRAS 16293-2422 (˜85 K). The deuterium fractionation ratio for CCH and H2CO are obtained to be 0.06-0.01, which are an order of magnitude lower than that found in the hot corino. Furthermore c-C3H2, whose production pathway is related to carbon-chain molecules, is abundant, and its rotation temperature is similar to that of CH3OH. From these results, it is likely that the RCrA IRS7B is a borderline source between the hot corinos and the WCCC sources. A related survey in the 230 GHz band is in progress for full characterization of the chemical composition of this low-mass protostellar source (Lindberg et al. 2011).

  8. Static and Wind Tunnel Aero-Performance Tests of NASA AST Separate Flow Nozzle Noise Reduction Configurations

    NASA Technical Reports Server (NTRS)

    Mikkelsen, Kevin L.; McDonald, Timothy J.; Saiyed, Naseem (Technical Monitor)

    2001-01-01

    This report presents the results of cold flow model tests to determine the static and wind tunnel performance of several NASA AST separate flow nozzle noise reduction configurations. The tests were conducted by Aero Systems Engineering, Inc., for NASA Glenn Research Center. The tests were performed in the Channels 14 and 6 static thrust stands and the Channel 10 transonic wind tunnel at the FluiDyne Aerodynamics Laboratory in Plymouth, Minnesota. Facility checkout tests were made using standard ASME long-radius metering nozzles. These tests demonstrated facility data accuracy at flow conditions similar to the model tests. Channel 14 static tests reported here consisted of 21 ASME nozzle facility checkout tests and 57 static model performance tests (including 22 at no charge). Fan nozzle pressure ratio varied from 1.4 to 2.0, and fan to core total pressure ratio varied from 1.0 to 1.19. Core to fan total temperature ratio was 1.0. Channel 10 wind tunnel tests consisted of 15 tests at Mach number 0.28 and 31 tests at Mach 0.8. The sting was checked out statically in Channel 6 before the wind tunnel tests. In the Channel 6 facility, 12 ASME nozzle data points were taken and 7 model data points were taken. In the wind tunnel, fan nozzle pressure ratio varied from 1.73 to 2.8, and fan to core total pressure ratio varied from 1.0 to 1.19. Core to fan total temperature ratio was 1.0. Test results include thrust coefficients, thrust vector angle, core and fan nozzle discharge coefficients, total pressure and temperature charging station profiles, and boat-tail static pressure distributions in the wind tunnel.

  9. Investigating the relation between CO (3-2) and far-infrared luminosities for nearby merging galaxies using ASTE

    NASA Astrophysics Data System (ADS)

    Michiyama, Tomonari; Iono, Daisuke; Nakanishi, Kouichiro; Ueda, Junko; Saito, Toshiki; Ando, Misaki; Kaneko, Hiroyuki; Yamashita, Takuji; Matsuda, Yuichi; Hatsukade, Bunyo; Kikuchi, Kenichi; Komugi, Shinya; Muto, Takayuki

    2016-09-01

    We present the new single-dish CO (3-2) emission data obtained toward 19 early-stage and 7 late-stage nearby merging galaxies using the Atacama Submillimeter Telescope Experiment (ASTE). Combining with the single-dish and interferometric data of galaxies observed in previous studies, we investigate the relation between the CO (3-2) luminosity (L^' }_CO(3-2)) and the far-infrared luminosity (LFIR) in a sample of 29 early-stage and 31 late-stage merging galaxies, and 28 nearby isolated spiral galaxies. We find that normal isolated spiral galaxies and merging galaxies have different slopes (α) in the log L^' }_CO(3-2)-log LFIR plane (α ˜ 0.79 for spirals and ˜1.12 for mergers). The large slope (α > 1) for merging galaxies can be interpreted as evidence for increasing star formation efficiency (SFE = L_FIR/L^' }_CO(3-2)) as a function of LFIR. Comparing our results with sub-kpc-scale local star formation and global starburst activity in the high-z universe, we find deviations from the linear relationship in the log L^' }_CO(3-2)-log LFIR plane for the late-stage mergers and high-z star-forming galaxies. Finally, we find that the average SFE gradually increases from isolated galaxies to merging galaxies and to high-z submillimeter galaxies/quasi-stellar objects. By comparing our findings with results from numerical simulations, we suggest that: (1) inefficient starbursts triggered by disk-wide dense clumps occur in the early stage of interaction, and (2) efficient starbursts triggered by central concentration of gas occur in the final stage. A systematic high spatial resolution survey of diffuse- and dense-gas tracers is the key to confirming this scenario.

  10. Good Agreements Make Good Friends

    PubMed Central

    Han, The Anh; Pereira, Luís Moniz; Santos, Francisco C.; Lenaerts, Tom

    2013-01-01

    When starting a new collaborative endeavor, it pays to establish upfront how strongly your partner commits to the common goal and what compensation can be expected in case the collaboration is violated. Diverse examples in biological and social contexts have demonstrated the pervasiveness of making prior agreements on posterior compensations, suggesting that this behavior could have been shaped by natural selection. Here, we analyze the evolutionary relevance of such a commitment strategy and relate it to the costly punishment strategy, where no prior agreements are made. We show that when the cost of arranging a commitment deal lies within certain limits, substantial levels of cooperation can be achieved. Moreover, these levels are higher than that achieved by simple costly punishment, especially when one insists on sharing the arrangement cost. Not only do we show that good agreements make good friends, agreements based on shared costs result in even better outcomes. PMID:24045873

  11. Quick Guide: Power Purchase Agreements

    SciTech Connect

    2010-06-25

    Introduction to Federal power purchase agreements (PPAs), including available FEMP services and technical assistance as well as questions to ask when evaluating PPAs for a Federal renewable energy project.

  12. Empirical agreement in model validation.

    PubMed

    Jebeile, Julie; Barberousse, Anouk

    2016-04-01

    Empirical agreement is often used as an important criterion when assessing the validity of scientific models. However, it is by no means a sufficient criterion as a model can be so adjusted as to fit available data even though it is based on hypotheses whose plausibility is known to be questionable. Our aim in this paper is to investigate into the uses of empirical agreement within the process of model validation.

  13. Plasma aspartate aminotransferase (AST), glutamate dehydrogenase (GLDH) and gamma-glutamyl transpeptidase (GGT) activities in water buffaloes with experimental subclinical fasciolosis.

    PubMed

    Yang, Q; Mao, W H; Ferre, I; Bayón, J E; Mao, X Z; González-Gallego, J

    1998-07-31

    The effect of chronic Fasciola hepatica infection on the activity of plasma aspartate aminotransferase (AST), glutamate dehydrogenase (GLDH) and gamma-glutamyl transpeptidase (GGT) was investigated in water buffaloes dosed daily with 60 F. hepatica metacercariae over 20 days. Experimental fluke infection caused no clinical signs but provoked an increase in plasma level of IgG directed against F. hepatica from 4 weeks after infection. There was a significant increase in plasma AST from 6 weeks post-infection. Maximal values were reached at 14 weeks and remained significantly elevated by 23 weeks. Plasma GLDH was significantly elevated from 6 to 21 weeks post-infection. Significant increases in plasma GGT occurred from 8 to 26 weeks post-infection, reaching maximal values at 15 weeks. This study shows that plasma enzyme activities may be useful in studies of fluke-induced liver damage in water buffaloes.

  14. Application Agreement and Integration Services

    NASA Technical Reports Server (NTRS)

    Driscoll, Kevin R.; Hall, Brendan; Schweiker, Kevin

    2013-01-01

    Application agreement and integration services are required by distributed, fault-tolerant, safety critical systems to assure required performance. An analysis of distributed and hierarchical agreement strategies are developed against the backdrop of observed agreement failures in fielded systems. The documented work was performed under NASA Task Order NNL10AB32T, Validation And Verification of Safety-Critical Integrated Distributed Systems Area 2. This document is intended to satisfy the requirements for deliverable 5.2.11 under Task 4.2.2.3. This report discusses the challenges of maintaining application agreement and integration services. A literature search is presented that documents previous work in the area of replica determinism. Sources of non-deterministic behavior are identified and examples are presented where system level agreement failed to be achieved. We then explore how TTEthernet services can be extended to supply some interesting application agreement frameworks. This document assumes that the reader is familiar with the TTEthernet protocol. The reader is advised to read the TTEthernet protocol standard [1] before reading this document. This document does not re-iterate the content of the standard.

  15. 7 CFR 247.4 - Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.4 Agreements. (a) What agreements are..., sex, or disability. (d) What is the duration of required agreements? Agreements between FNS and...

  16. 7 CFR 247.4 - Agreements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.4 Agreements. (a) What agreements are..., sex, or disability. (d) What is the duration of required agreements? Agreements between FNS and...

  17. Crystal Structure of N-succinylarginine Dihydrolase AstB, Bound to Substrate and Product, an Enzyme from the Arginine Catabolic Pathway of Escherichia Coli

    SciTech Connect

    Tocilj,A.; Schrag, J.; Li, Y.; Schneider, B.; Reitzer, L.; Matte, A.; Cygler, M.

    2005-01-01

    The ammonia-producing arginine succinyltransferase pathway is the major pathway in Escherichia coli and related bacteria for arginine catabolism as a sole nitrogen source. This pathway consists of five steps, each catalyzed by a distinct enzyme. Here we report the crystal structure of N-succinylarginine dihydrolase AstB, the second enzyme of the arginine succinyltransferase pathway, providing the first structural insight into enzymes from this pathway. The enzyme exhibits a pseudo 5-fold symmetric {alpha}/{beta} propeller fold of circularly arranged {beta}{beta}{alpha}{beta} modules enclosing the active site. The crystal structure indicates clearly that this enzyme belongs to the amidinotransferase (AT) superfamily and that the active site contains a Cys-His-Glu triad characteristic of the AT superfamily. Structures of the complexes of AstB with the reaction product and a C365S mutant with bound the N-succinylarginine substrate suggest a catalytic mechanism that consists of two cycles of hydrolysis and ammonia release, with each cycle utilizing a mechanism similar to that proposed for arginine deiminases. Like other members of the AT superfamily of enzymes, AstB possesses a flexible loop that is disordered in the absence of substrate and assumes an ordered conformation upon substrate binding, shielding the ligand from the bulk solvent, thereby controlling substrate access and product release.

  18. Gender agreement and multiple referents.

    PubMed

    Finocchiaro, Chiara; Mahon, Bradford Z; Caramazza, Alfonso

    2008-01-01

    We report a new pattern of usage in current, spoken Italian that has implications for both psycholinguistic models of language production and linguistic theories of language change. In Italian, gender agreement is mandatory for both singular and plural nouns. However, when two or more nouns of different grammatical gender appear in a conjoined noun phrase (NP), masculine plural agreement is required. In this study, we combined on-line and off-line methodologies in order to assess the mechanisms involved in gender marking in the context of multiple referents. The results of two pronoun production tasks showed that plural feminine agreement was significantly more difficult than plural masculine agreement. In a separate study using offline judgements of acceptability, we found that agreement violations in Italian are tolerated more readily in the case of feminine conjoined noun phrases (e.g., la mela e la banana 'the:fem apple:fem and the: fem banana: fem') than masculine conjoined noun phrases (e.g., il fiore e il libro 'the:mas flower: mas and the:mas book:mas'). Implications of these results are discussed both at the level of functional architecture within the language production system and at the level of changes in language use. PMID:21037930

  19. Gender agreement and multiple referents.

    PubMed

    Finocchiaro, Chiara; Mahon, Bradford Z; Caramazza, Alfonso

    2008-01-01

    We report a new pattern of usage in current, spoken Italian that has implications for both psycholinguistic models of language production and linguistic theories of language change. In Italian, gender agreement is mandatory for both singular and plural nouns. However, when two or more nouns of different grammatical gender appear in a conjoined noun phrase (NP), masculine plural agreement is required. In this study, we combined on-line and off-line methodologies in order to assess the mechanisms involved in gender marking in the context of multiple referents. The results of two pronoun production tasks showed that plural feminine agreement was significantly more difficult than plural masculine agreement. In a separate study using offline judgements of acceptability, we found that agreement violations in Italian are tolerated more readily in the case of feminine conjoined noun phrases (e.g., la mela e la banana 'the:fem apple:fem and the: fem banana: fem') than masculine conjoined noun phrases (e.g., il fiore e il libro 'the:mas flower: mas and the:mas book:mas'). Implications of these results are discussed both at the level of functional architecture within the language production system and at the level of changes in language use.

  20. Gender agreement and multiple referents

    PubMed Central

    Finocchiaro, Chiara; Mahon, Bradford Z.; Caramazza, Alfonso

    2010-01-01

    We report a new pattern of usage in current, spoken Italian that has implications for both psycholinguistic models of language production and linguistic theories of language change. In Italian, gender agreement is mandatory for both singular and plural nouns. However, when two or more nouns of different grammatical gender appear in a conjoined noun phrase (NP), masculine plural agreement is required. In this study, we combined on-line and off-line methodologies in order to assess the mechanisms involved in gender marking in the context of multiple referents. The results of two pronoun production tasks showed that plural feminine agreement was significantly more difficult than plural masculine agreement. In a separate study using offline judgements of acceptability, we found that agreement violations in Italian are tolerated more readily in the case of feminine conjoined noun phrases (e.g., la mela e la banana ‘the:fem apple:fem and the: fem banana: fem’) than masculine conjoined noun phrases (e.g., il fiore e il libro ‘the:mas flower: mas and the:mas book:mas’). Implications of these results are discussed both at the level of functional architecture within the language production system and at the level of changes in language use.* PMID:21037930

  1. Fibroscan Compared to FIB-4, APRI, and AST/ALT Ratio for Assessment of Liver Fibrosis in Saudi Patients With Nonalcoholic Fatty Liver Disease

    PubMed Central

    Fallatah, Hind I.; Akbar, Hisham O.; Fallatah, Alyaa M.

    2016-01-01

    Background Nonalcoholic fatty liver disease (NAFLD) is being increasingly recognized as a cause of chronic liver disease. It has also been associated with devastating outcomes such as decompensated liver cirrhosis and hepatocellular carcinoma, as well as diabetes and metabolic syndrome. Objectives This study was conducted in order to assess liver fibrosis using Fibroscan, and to compare these results to the use of Fibrosis-4 (FIB-4) scores, AST platelet ratio index (APRI scores), and the AST/ALT ratios on NAFLD patients. Patients and Methods A cross sectional study was conducted on NAFLD patients who underwent Fibroscan examinations between September 1, 2011 and June 30, 2014. Demographic data was collected, including sex, age, and nationality; serum alanine aminotransferase levels (ALT, 30 - 65 U/L), serum aspartate aminotransferase levels (AST, 15 - 37 U/L), and platelet counts (150 - 400 k/μL) were also determined. The stages of fibrosis (F0 1 - 6, F1 6.1 - 7, F2 7 - 9, F3 9.1 - 10.3, and F4 ≥ 10.4) were defined in kPa. For each patient, the AST/ALT ratio was also measured. The results of APRI and FIB-4 were compared with the Fibroscan fibrosis scores. Results The results of 122 patients were analyzed, including 65 (53.3%) males with a mean age of 50.2 years (SD: 13.7; range: 18 - 86). The males were significantly younger than the females (48.7 years (SD: 16.03) versus 51.8 years (SD: 10.3 P = 0.05), respectively). The mean stiffness score was 12.02 (SD: 12.7) kPa. Forty-four patients (36%) had advanced fibrosis. The mean platelet and serum ALT levels were normal. There was a significant positive correlation between the Fibroscan results and the AST/ALT ratios, the APRI scores, and the FIB-4 results. Similarly, there was a significant positive correlation between age and fibrosis score, and a significant negative correlation between platelet count and stiffness score. Conclusions The data showed that more than one-third of the cohort exhibited advanced

  2. Experience and Grammatical Agreement: Statistical Learning Shapes Number Agreement Production

    ERIC Educational Resources Information Center

    Haskell, Todd R.; Thornton, Robert; MacDonald, Maryellen C.

    2010-01-01

    A robust result in research on the production of grammatical agreement is that speakers are more likely to produce an erroneous verb with phrases such as "the key to the cabinets", with a singular noun followed by a plural one, than with phrases such as "the keys to the cabinet", where a plural noun is followed by a singular. These asymmetries are…

  3. Authenticated algorithms for Byzantine agreement

    SciTech Connect

    Dolev, D.; Strong, H.R.

    1983-11-01

    Reaching agreement in a distributed system in the presence of fault processors is a central issue for reliable computer systems. Using an authentication protocol, one can limit the undetected behavior of faulty processors to a simple failure to relay messages to all intended targets. In this paper the authors show that, in spite of such an ability to limit faulty behavior, and no matter what message types or protocols are allowed, reaching (Byzantine) agreement requires at least t+1 phases or rounds of information exchange, where t is an upper bound on the number of faulty processors. They present algorithms for reaching agreement based on authentication that require a total number of messages sent by correctly operating processors that is polynomial in both t and the number of processors, n. The best algorithm uses only t+1 phases and o(nt) messages. 9 references.

  4. Articulation Agreements Ease the Way.

    ERIC Educational Resources Information Center

    Reese, Susan

    2002-01-01

    Articulation agreements between secondary and postsecondary institutions often provide for granting college credit for course work completed at another institution. They have been described as programs designed to create pathways of learning that ease the transition of students from secondary to postsecondary levels. (JOW)

  5. Block Transfer Agreement Evaluation Project

    ERIC Educational Resources Information Center

    Bastedo, Helena

    2010-01-01

    The objective of this project is to evaluate for the British Columbia Council on Admissions and Transfer (BCCAT) the effectiveness of block transfer agreements (BTAs) in the BC Transfer System and recommend steps to be taken to improve their effectiveness. Findings of this study revealed that institutions want to expand block credit transfer;…

  6. 48 CFR 16.702 - Basic agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Basic agreements. 16.702... AND CONTRACT TYPES TYPES OF CONTRACTS Agreements 16.702 Basic agreements. (a) Description. A basic... attachment the required and applicable clauses agreed upon in the basic agreement. A basic agreement is not...

  7. 48 CFR 16.702 - Basic agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Basic agreements. 16.702... AND CONTRACT TYPES TYPES OF CONTRACTS Agreements 16.702 Basic agreements. (a) Description. A basic... attachment the required and applicable clauses agreed upon in the basic agreement. A basic agreement is not...

  8. 48 CFR 16.702 - Basic agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Basic agreements. 16.702... AND CONTRACT TYPES TYPES OF CONTRACTS Agreements 16.702 Basic agreements. (a) Description. A basic... attachment the required and applicable clauses agreed upon in the basic agreement. A basic agreement is not...

  9. 48 CFR 16.702 - Basic agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Basic agreements. 16.702... AND CONTRACT TYPES TYPES OF CONTRACTS Agreements 16.702 Basic agreements. (a) Description. A basic... attachment the required and applicable clauses agreed upon in the basic agreement. A basic agreement is not...

  10. 48 CFR 16.702 - Basic agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Basic agreements. 16.702... AND CONTRACT TYPES TYPES OF CONTRACTS Agreements 16.702 Basic agreements. (a) Description. A basic... attachment the required and applicable clauses agreed upon in the basic agreement. A basic agreement is not...

  11. 78 FR 15951 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-13

    ... agreement. Agreement No.: 012196. Title: MSC/CSAV Ecuador--North Europe Vessel Sharing Agreement. Parties... on the U.S. East Coast on the one hand, and from ports on the U.S. East Coast to Panama and...

  12. 75 FR 11180 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ....gov . Agreement No.: 011730-003. Title: GWF/Dole Space Charter and Sailing Agreement. Parties: Dole... China-US Pacific Coast Two-Loop Space Charter, Sailing and Cooperative Working Agreement. Parties:...

  13. 40 CFR 35.1615 - Substate agreements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 CFR 33.240 (Intergovernmental agreements). A State may enter into an agreement with a substate... STATE AND LOCAL ASSISTANCE Cooperative Agreements for Protecting and Restoring Publicly Owned...

  14. 40 CFR 35.1615 - Substate agreements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 CFR 33.240 (Intergovernmental agreements). A State may enter into an agreement with a substate... STATE AND LOCAL ASSISTANCE Cooperative Agreements for Protecting and Restoring Publicly Owned...

  15. 40 CFR 35.1615 - Substate agreements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 CFR 33.240 (Intergovernmental agreements). A State may enter into an agreement with a substate... STATE AND LOCAL ASSISTANCE Cooperative Agreements for Protecting and Restoring Publicly Owned...

  16. 40 CFR 35.1615 - Substate agreements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 CFR 33.240 (Intergovernmental agreements). A State may enter into an agreement with a substate... STATE AND LOCAL ASSISTANCE Cooperative Agreements for Protecting and Restoring Publicly Owned...

  17. 40 CFR 35.1615 - Substate agreements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 CFR 33.240 (Intergovernmental agreements). A State may enter into an agreement with a substate... STATE AND LOCAL ASSISTANCE Cooperative Agreements for Protecting and Restoring Publicly Owned...

  18. 77 FR 61751 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-11

    ... Agreement. Parties: Crowley Latin America Services, LLC and A.P. Moller-Maersk A/S Filing Party: Wayne R... . Agreement No.: 012155-001. Title: MSC/Zim South America East Coast Vessel Sharing Agreement....

  19. Limiting technology by negotiated agreement

    SciTech Connect

    Carnesale, A.

    1983-01-01

    The author concentrates on anti-ballistic missile (ABM) systems as an example of a continuing effort to limit technology by negotiated agreement. He first discusses the ABM treaty of 1972, ratified by both the US and the USSR. Afterwards, he briefly treats each of the following: ballistic missile defense (BMD) dilemmas; nature of the BMD choice; technology; economics; deterrence; nuclear warfighting; relations with allies; arms control; Star Wars; and on limiting technology.

  20. Measurement Challenges in International Agreements

    NASA Astrophysics Data System (ADS)

    Luke, John

    2006-10-01

    Making measurements in support of international agreements can pose many challenges both from a policy and science point of view. Policy issues may arise because physics measurements made in the area of arms control or disarmament may be deemed too intrusive since they could possibly reveal sensitive information about the material that is being interrogated. Therefore, agreements must include a framework for safeguarding against the potential release of this information. Most of the scientific issues center around the fact that it is desirable to make high quality measurements without any operator interaction. This leads to the development of instrumentation and software that are very stable and robust. Due to different concerns, policy and science priorities may be at odds with one another. Therefore, it is the scientist's challenge - in this field - to keep policy makers informed by conveying what is technically possible and what is not in a manner that is easily understood and also negotiable. In this paper we will discuss some of the technology that has been developed to address some of these challenges in various international and model agreements. We will discuss the principle of informational barrier used in these measurement technologies to safeguard the release of sensitive information. We will also discuss some of the pitfalls that may arise when policy is ill informed about the physical constraints in the making of measurements of nuclear materials.

  1. 32 CFR 78.7 - Standard agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Standard agreement. 78.7 Section 78.7 National... VOLUNTARY STATE TAX WITHHOLDING FROM RETIRED PAY § 78.7 Standard agreement. Standard Agreement For Voluntary..., hereafter referred to as the “Standard Agreement,” establishes administrative procedures and...

  2. 48 CFR 3416.702 - Basic agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Basic agreements. 3416.702... CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Agreements 3416.702 Basic agreements. (a)-(d) (e) Negotiated overhead rates. Basic agreements may include negotiated overhead rates for...

  3. 78 FR 26779 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-08

    ... reflects the suspension of the agreement, effective May 1, 2013 through April 14, 2015. Agreement No... the fact that the parties have agreed to charter and rationalize vessel space among themselves and...). Agreement No.: 012206. Title: Industria Armamento Meridionale S.P.A./K-Line Space Charter Agreement....

  4. 2 CFR 182.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C. 6305... development agreements as defined in 15 U.S.C. 3710a. ... MANAGEMENT AND BUDGET GOVERNMENTWIDE GUIDANCE FOR GRANTS AND AGREEMENTS NATIONAL POLICY...

  5. 5 CFR 2421.20 - Election agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Election agreement. 2421.20 Section 2421... Election agreement. Election agreement means an agreement under part 2422 of this subchapter signed by all... representation election in an appropriate unit....

  6. 5 CFR 2421.20 - Election agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 3 2012-01-01 2012-01-01 false Election agreement. 2421.20 Section 2421... Election agreement. Election agreement means an agreement under part 2422 of this subchapter signed by all... representation election in an appropriate unit....

  7. 5 CFR 2421.20 - Election agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Election agreement. 2421.20 Section 2421... Election agreement. Election agreement means an agreement under part 2422 of this subchapter signed by all... representation election in an appropriate unit....

  8. 5 CFR 2421.20 - Election agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 3 2014-01-01 2014-01-01 false Election agreement. 2421.20 Section 2421... Election agreement. Election agreement means an agreement under part 2422 of this subchapter signed by all... representation election in an appropriate unit....

  9. 5 CFR 2421.20 - Election agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Election agreement. 2421.20 Section 2421... Election agreement. Election agreement means an agreement under part 2422 of this subchapter signed by all... representation election in an appropriate unit....

  10. 7 CFR 1948.98 - Grant agreements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 13 2013-01-01 2013-01-01 false Grant agreements. 1948.98 Section 1948.98 Agriculture... § 1948.98 Grant agreements. The following Grant Agreements are a part of this regulation. (a) Exhibit A of this subpart is a Grant Agreement for Growth Management and Housing Planning Grants for...

  11. 7 CFR 1948.98 - Grant agreements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 13 2011-01-01 2009-01-01 true Grant agreements. 1948.98 Section 1948.98 Agriculture... § 1948.98 Grant agreements. The following Grant Agreements are a part of this regulation. (a) Exhibit A of this subpart is a Grant Agreement for Growth Management and Housing Planning Grants for...

  12. 7 CFR 1415.11 - Restoration agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Restoration agreements. 1415.11 Section 1415.11... Restoration agreements. (a) Restoration agreements are only authorized to be used in conjunction with... a restoration agreement is needed. Such a determination is also subject to the availability...

  13. 7 CFR 1415.11 - Restoration agreements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Restoration agreements. 1415.11 Section 1415.11... Restoration agreements. (a) Restoration agreements are only authorized to be used in conjunction with... a restoration agreement is needed. Such a determination is also subject to the availability...

  14. 7 CFR 947.111 - Marketing agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Marketing agreement. 947.111 Section 947.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Definitions § 947.111 Marketing agreement. Marketing agreement means Marketing Agreement No. 114, as amended....

  15. 7 CFR 947.111 - Marketing agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Marketing agreement. 947.111 Section 947.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Definitions § 947.111 Marketing agreement. Marketing agreement means Marketing Agreement No. 114, as amended....

  16. 46 CFR 356.41 - Management agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Management agreements. 356.41 Section 356.41 Shipping..., Management Agreements and Exclusive or Long-Term Contracts § 356.41 Management agreements. (a) An owner or bareboat charterer of a Fishing Industry Vessel may enter into a management agreement with a Non-Citizen...

  17. 25 CFR 163.71 - Agreement funding.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Agreement funding. 163.71 Section 163.71 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Cooperative Agreements § 163.71 Agreement funding. In cooperative agreements, the Secretary is authorized to advance...

  18. 25 CFR 163.71 - Agreement funding.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Agreement funding. 163.71 Section 163.71 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Cooperative Agreements § 163.71 Agreement funding. In cooperative agreements, the Secretary is authorized to advance...

  19. 25 CFR 163.71 - Agreement funding.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Agreement funding. 163.71 Section 163.71 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Cooperative Agreements § 163.71 Agreement funding. In cooperative agreements, the Secretary is authorized to advance...

  20. 25 CFR 163.71 - Agreement funding.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Agreement funding. 163.71 Section 163.71 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Cooperative Agreements § 163.71 Agreement funding. In cooperative agreements, the Secretary is authorized to advance...

  1. 25 CFR 163.71 - Agreement funding.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Agreement funding. 163.71 Section 163.71 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Cooperative Agreements § 163.71 Agreement funding. In cooperative agreements, the Secretary is authorized to advance...

  2. 77 FR 10743 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-23

    ... . Agreement No.: 011353-036. Title: The Credit Agreement. Parties: Crowley Latin America Services, LLC; Dole..., DC 20006-4007. Synopsis: The amendment deletes Crowley Latin American Services, LLC and a King Ocean entity as a party to the Agreement. Agreement No.: 012155. Title: MSC/Zim South America East Coast...

  3. 7 CFR 947.111 - Marketing agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Marketing agreement. 947.111 Section 947.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... Definitions § 947.111 Marketing agreement. Marketing agreement means Marketing Agreement No. 114, as amended....

  4. 7 CFR 947.111 - Marketing agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Marketing agreement. 947.111 Section 947.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... Definitions § 947.111 Marketing agreement. Marketing agreement means Marketing Agreement No. 114, as amended....

  5. 7 CFR 947.111 - Marketing agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Marketing agreement. 947.111 Section 947.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Definitions § 947.111 Marketing agreement. Marketing agreement means Marketing Agreement No. 114, as amended....

  6. 27 CFR 70.485 - Closing agreements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2012-04-01 2011-04-01 true Closing agreements. 70.485... Relating to Alcohol, Tobacco, Firearms, and Explosives Administrative Remedies § 70.485 Closing agreements... taxable period ending prior or subsequent to the date of such agreement. A closing agreement may...

  7. 27 CFR 70.485 - Closing agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2013-04-01 2013-04-01 false Closing agreements. 70.485... Relating to Alcohol, Tobacco, Firearms, and Explosives Administrative Remedies § 70.485 Closing agreements... taxable period ending prior or subsequent to the date of such agreement. A closing agreement may...

  8. 27 CFR 70.485 - Closing agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Closing agreements. 70.485... Relating to Alcohol, Tobacco, Firearms, and Explosives Administrative Remedies § 70.485 Closing agreements... taxable period ending prior or subsequent to the date of such agreement. A closing agreement may...

  9. 27 CFR 70.485 - Closing agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2011-04-01 2011-04-01 false Closing agreements. 70.485... Relating to Alcohol, Tobacco, Firearms, and Explosives Administrative Remedies § 70.485 Closing agreements... taxable period ending prior or subsequent to the date of such agreement. A closing agreement may...

  10. 27 CFR 70.485 - Closing agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2014-04-01 2014-04-01 false Closing agreements. 70.485... Relating to Alcohol, Tobacco, Firearms, and Explosives Administrative Remedies § 70.485 Closing agreements... taxable period ending prior or subsequent to the date of such agreement. A closing agreement may...

  11. 40 CFR 46.170 - Fellowship agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Fellowship agreement. 46.170 Section 46... FELLOWSHIPS Award § 46.170 Fellowship agreement. (a) The “Fellowship Agreement” (EPA Form 5770-8) is the written agreement, including amendments, between EPA and you. The fellowship agreement will state...

  12. 40 CFR 46.170 - Fellowship agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Fellowship agreement. 46.170 Section 46... FELLOWSHIPS Award § 46.170 Fellowship agreement. (a) The “Fellowship Agreement” (EPA Form 5770-8) is the written agreement, including amendments, between EPA and you. The fellowship agreement will state...

  13. 40 CFR 46.170 - Fellowship agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Fellowship agreement. 46.170 Section 46... FELLOWSHIPS Award § 46.170 Fellowship agreement. (a) The “Fellowship Agreement” (EPA Form 5770-8) is the written agreement, including amendments, between EPA and you. The fellowship agreement will state...

  14. 40 CFR 46.170 - Fellowship agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Fellowship agreement. 46.170 Section 46... FELLOWSHIPS Award § 46.170 Fellowship agreement. (a) The “Fellowship Agreement” (EPA Form 5770-8) is the written agreement, including amendments, between EPA and you. The fellowship agreement will state...

  15. 40 CFR 46.170 - Fellowship agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Fellowship agreement. 46.170 Section 46... FELLOWSHIPS Award § 46.170 Fellowship agreement. (a) The “Fellowship Agreement” (EPA Form 5770-8) is the written agreement, including amendments, between EPA and you. The fellowship agreement will state...

  16. International Agreement on Planetary Protection

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The maintenance of a NASA policy, is consistent with international agreements. The planetary protection policy management in OSS, with Field Center support. The advice from internal and external advisory groups (NRC, NAC/Planetary Protection Task Force). The technology research and standards development in bioload characterization. The technology research and development in bioload reduction/sterilization. This presentation focuses on: forward contamination - research on the potential for Earth life to exist on other bodies, improved strategies for planetary navigation and collision avoidance, and improved procedures for sterile spacecraft assembly, cleaning and/or sterilization; and backward contamination - development of sample transfer and container sealing technologies for Earth return, improvement in sample return landing target assessment and navigation strategy, planning for sample hazard determination requirements and procedures, safety certification, (liaison to NEO Program Office for compositional data on small bodies), facility planning for sample recovery system, quarantine, and long-term curation of 4 returned samples.

  17. Sexual Agreements among Gay Male Couples

    PubMed Central

    Hoff, Colleen H.; Beougher, Sean C.

    2009-01-01

    Many gay male couples make agreements about whether or not to permit sex with outside partners, yet little is known about the development and maintenance of these agreements, their impact on relationships, and whether they are an effective HIV prevention strategy. Using semi-structured, qualitative interviews, 39 gay male couples were asked about their sexual agreements and about other relationship dynamics that might affect their agreements. Analysis revealed a wide range of agreement types, all of which are presented along a continuum rather than as discrete categories. For couples with open agreements, most placed rules or conditions limiting when, where, how often, and with whom outside sex was permitted. Although motivations for having agreements varied, HIV prevention did not rank as a primary factor for any couple. Most couples had congruous agreements; however, a small number reported discrepancies which may increase HIV transmission risk. How couples handled breaks in their agreements also varied, depending on what condition was broken, whether it was disclosed, and the partner's reaction. Additional results include differences in agreement type and motivations for having an agreement based on couple serostatus. Overall, agreements benefited couples by providing boundaries for the relationship, supporting a non-heteronormative identity, and fulfilling the sexual needs of the couple. Future prevention efforts involving gay couples must address the range of agreement types and the meanings couples ascribe to them, in addition to tempering safety messages with the relationship issues that are important to and faced by gay couples. PMID:18686027

  18. 22 CFR 124.1 - Manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Manufacturing license agreements and technical... ARMS REGULATIONS AGREEMENTS, OFF-SHORE PROCUREMENT AND OTHER DEFENSE SERVICES § 124.1 Manufacturing... manufacturing license agreements, technical assistance agreements, distribution agreements, or...

  19. 22 CFR 124.1 - Manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Manufacturing license agreements and technical... ARMS REGULATIONS AGREEMENTS, OFF-SHORE PROCUREMENT AND OTHER DEFENSE SERVICES § 124.1 Manufacturing... manufacturing license agreements, technical assistance agreements, distribution agreements, or...

  20. 22 CFR 124.1 - Manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Manufacturing license agreements and technical... ARMS REGULATIONS AGREEMENTS, OFF-SHORE PROCUREMENT, AND OTHER DEFENSE SERVICES § 124.1 Manufacturing... manufacturing license agreements, technical assistance agreements, distribution agreements, or...

  1. 22 CFR 124.1 - Manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Manufacturing license agreements and technical... ARMS REGULATIONS AGREEMENTS, OFF-SHORE PROCUREMENT AND OTHER DEFENSE SERVICES § 124.1 Manufacturing... manufacturing license agreements, technical assistance agreements, distribution agreements, or...

  2. 22 CFR 124.1 - Manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Manufacturing license agreements and technical... ARMS REGULATIONS AGREEMENTS, OFF-SHORE PROCUREMENT AND OTHER DEFENSE SERVICES § 124.1 Manufacturing... manufacturing license agreements, technical assistance agreements, distribution agreements, or...

  3. AzTEC/ASTE Millimeter-wave Monitoring and Target-of-opportunity Observations of Selected Radio-bright Fermi-detected Gamma-ray Blazars and GRBs

    NASA Astrophysics Data System (ADS)

    Stacy, J. Gregory; Wilson, G.; AzTEC/ASTE Collaboration

    2010-11-01

    We report on correlative millimeter-wave radio observations at 1.1 mm of high-priority Fermi-detected gamma-ray blazars using the AzTEC bolometer-array camera mounted on the 10-m ASTE radio telescope in northern Chile. These observations were carried out during the latter part of the 2008 observing season, overlapping with the first months of operation of the Fermi Observatory. High-priority blazars were monitored and we responded as well to Fermi alerts of elevated gamma-ray emission or flaring activity. We also report on the upper limits obtained to millimeter-wave emission in the early afterglow from GRB 081121. These correlative measurements constituted a pilot observing program that will be extended and expanded to include numerous additional gamma-ray targets for the Large Millimeter Telescope as part of its commissioning operations over the coming year. This work is supported in part by the National Science Foundation.

  4. Measurement of CP violation parameters and polarisation fractions in {B}s^0to J/ψ {overline{K}}^{ast 0} decays

    NASA Astrophysics Data System (ADS)

    Aaij, R.; Adeva, B.; Adinolfi, M.; Affolder, A.; Ajaltouni, Z.; Akar, S.; Albrecht, J.; Alessio, F.; Alexander, M.; Ali, S.; Alkhazov, G.; Alvarez Cartelle, P.; Alves, A. A.; Amato, S.; Amerio, S.; Amhis, Y.; An, L.; Anderlini, L.; Anderson, J.; Andreassi, G.; Andreotti, M.; Andrews, J. E.; Appleby, R. B.; Aquines Gutierrez, O.; Archilli, F.; d'Argent, P.; Artamonov, A.; Artuso, M.; Aslanides, E.; Auriemma, G.; Baalouch, M.; Bachmann, S.; Back, J. J.; Badalov, A.; Baesso, C.; Baldini, W.; Barlow, R. J.; Barschel, C.; Barsuk, S.; Barter, W.; Batozskaya, V.; Battista, V.; Bay, A.; Beaucourt, L.; Beddow, J.; Bedeschi, F.; Bediaga, I.; Bel, L. J.; Bellee, V.; Belloli, N.; Belyaev, I.; Ben-Haim, E.; Bencivenni, G.; Benson, S.; Benton, J.; Berezhnoy, A.; Bernet, R.; Bertolin, A.; Bettler, M.-O.; van Beuzekom, M.; Bien, A.; Bifani, S.; Billoir, P.; Bird, T.; Birnkraut, A.; Bizzeti, A.; Blake, T.; Blanc, F.; Blouw, J.; Blusk, S.; Bocci, V.; Bondar, A.; Bondar, N.; Bonivento, W.; Borghi, S.; Borsato, M.; Bowcock, T. J. V.; Bowen, E.; Bozzi, C.; Braun, S.; Britsch, M.; Britton, T.; Brodzicka, J.; Brook, N. H.; Buchanan, E.; Bursche, A.; Buytaert, J.; Cadeddu, S.; Calabrese, R.; Calvi, M.; Calvo Gomez, M.; Campana, P.; Campora Perez, D.; Capriotti, L.; Carbone, A.; Carboni, G.; Cardinale, R.; Cardini, A.; Carniti, P.; Carson, L.; Carvalho Akiba, K.; Casse, G.; Cassina, L.; Castillo Garcia, L.; Cattaneo, M.; Cauet, Ch.; Cavallero, G.; Cenci, R.; Charles, M.; Charpentier, Ph.; Chefdeville, M.; Chen, S.; Cheung, S.-F.; Chiapolini, N.; Chrzaszcz, M.; Cid Vidal, X.; Ciezarek, G.; Clarke, P. E. L.; Clemencic, M.; Cliff, H. V.; Closier, J.; Coco, V.; Cogan, J.; Cogneras, E.; Cogoni, V.; Cojocariu, L.; Collazuol, G.; Collins, P.; Comerma-Montells, A.; Contu, A.; Cook, A.; Coombes, M.; Coquereau, S.; Corti, G.; Corvo, M.; Couturier, B.; Cowan, G. A.; Craik, D. C.; Crocombe, A.; Cruz Torres, M.; Cunliffe, S.; Currie, R.; D'Ambrosio, C.; Dall'Occo, E.; Dalseno, J.; David, P. N. Y.; Davis, A.; De Bruyn, K.; De Capua, S.; De Cian, M.; De Miranda, J. M.; De Paula, L.; De Simone, P.; Dean, C.-T.; Decamp, D.; Deckenhoff, M.; Del Buono, L.; Déléage, N.; Demmer, M.; Derkach, D.; Deschamps, O.; Dettori, F.; Dey, B.; Di Canto, A.; Di Ruscio, F.; Dijkstra, H.; Donleavy, S.; Dordei, F.; Dorigo, M.; Dosil Suárez, A.; Dossett, D.; Dovbnya, A.; Dreimanis, K.; Dufour, L.; Dujany, G.; Dupertuis, F.; Durante, P.; Dzhelyadin, R.; Dziurda, A.; Dzyuba, A.; Easo, S.; Egede, U.; Egorychev, V.; Eidelman, S.; Eisenhardt, S.; Eitschberger, U.; Ekelhof, R.; Eklund, L.; El Rifai, I.; Elsasser, Ch.; Ely, S.; Esen, S.; Evans, H. M.; Evans, T.; Falabella, A.; Färber, C.; Farley, N.; Farry, S.; Fay, R.; Ferguson, D.; Fernandez Albor, V.; Ferrari, F.; Ferreira Rodrigues, F.; Ferro-Luzzi, M.; Filippov, S.; Fiore, M.; Fiorini, M.; Firlej, M.; Fitzpatrick, C.; Fiutowski, T.; Fohl, K.; Fol, P.; Fontana, M.; Fontanelli, F.; Forty, R.; Francisco, O.; Frank, M.; Frei, C.; Frosini, M.; Fu, J.; Furfaro, E.; Gallas Torreira, A.; Galli, D.; Gallorini, S.; Gambetta, S.; Gandelman, M.; Gandini, P.; Gao, Y.; García Pardiñas, J.; Garra Tico, J.; Garrido, L.; Gascon, D.; Gaspar, C.; Gauld, R.; Gavardi, L.; Gazzoni, G.; Gerick, D.; Gersabeck, E.; Gersabeck, M.; Gershon, T.; Ghez, Ph.; Gianì, S.; Gibson, V.; Girard, O. G.; Giubega, L.; Gligorov, V. V.; Göbel, C.; Golubkov, D.; Golutvin, A.; Gomes, A.; Gotti, C.; Grabalosa Gándara, M.; Graciani Diaz, R.; Granado Cardoso, L. A.; Graugés, E.; Graverini, E.; Graziani, G.; Grecu, A.; Greening, E.; Gregson, S.; Griffith, P.; Grillo, L.; Grünberg, O.; Gui, B.; Gushchin, E.; Guz, Yu.; Gys, T.; Hadavizadeh, T.; Hadjivasiliou, C.; Haefeli, G.; Haen, C.; Haines, S. C.; Hall, S.; Hamilton, B.; Han, X.; Hansmann-Menzemer, S.; Harnew, N.; Harnew, S. T.; Harrison, J.; He, J.; Head, T.; Heijne, V.; Hennessy, K.; Henrard, P.; Henry, L.; van Herwijnen, E.; Heß, M.; Hicheur, A.; Hill, D.; Hoballah, M.; Hombach, C.; Hulsbergen, W.; Humair, T.; Hussain, N.; Hutchcroft, D.; Hynds, D.; Idzik, M.; Ilten, P.; Jacobsson, R.; Jaeger, A.; Jalocha, J.; Jans, E.; Jawahery, A.; Jing, F.; John, M.; Johnson, D.; Jones, C. R.; Joram, C.; Jost, B.; Jurik, N.; Kandybei, S.; Kanso, W.; Karacson, M.; Karbach, T. M.; Karodia, S.; Kecke, M.; Kelsey, M.; Kenyon, I. R.; Kenzie, M.; Ketel, T.; Khanji, B.; Khurewathanakul, C.; Klaver, S.; Klimaszewski, K.; Kochebina, O.; Kolpin, M.; Komarov, I.; Koopman, R. F.; Koppenburg, P.; Kozeiha, M.; Kravchuk, L.; Kreplin, K.; Kreps, M.; Krocker, G.; Krokovny, P.; Kruse, F.; Krzemien, W.; Kucewicz, W.; Kucharczyk, M.; Kudryavtsev, V.; Kuonen, A. K.; Kurek, K.; Kvaratskheliya, T.; Lacarrere, D.; Lafferty, G.; Lai, A.; Lambert, D.; Lanfranchi, G.; Langenbruch, C.; Langhans, B.; Latham, T.; Lazzeroni, C.; Le Gac, R.; van Leerdam, J.; Lees, J.-P.; Lefèvre, R.; Leflat, A.; Lefrançois, J.; Lemos Cid, E.; Leroy, O.; Lesiak, T.; Leverington, B.; Li, Y.; Likhomanenko, T.; Liles, M.; Lindner, R.; Linn, C.; Lionetto, F.; Liu, B.; Liu, X.; Loh, D.; Longstaff, I.; Lopes, J. H.; Lucchesi, D.; Lucio Martinez, M.; Luo, H.; Lupato, A.; Luppi, E.; Lupton, O.; Lusiani, A.; Machefert, F.; Maciuc, F.; Maev, O.; Maguire, K.; Malde, S.; Malinin, A.; Manca, G.; Mancinelli, G.; Manning, P.; Mapelli, A.; Maratas, J.; Marchand, J. F.; Marconi, U.; Marin Benito, C.; Marino, P.; Marks, J.; Martellotti, G.; Martin, M.; Martinelli, M.; Martinez Santos, D.; Martinez Vidal, F.; Martins Tostes, D.; Massafferri, A.; Matev, R.; Mathad, A.; Mathe, Z.; Matteuzzi, C.; Mauri, A.; Maurin, B.; Mazurov, A.; McCann, M.; McCarthy, J.; McNab, A.; McNulty, R.; Meadows, B.; Meier, F.; Meissner, M.; Melnychuk, D.; Merk, M.; Michielin, E.; Milanes, D. A.; Minard, M.-N.; Mitzel, D. S.; Molina Rodriguez, J.; Monroy, I. A.; Monteil, S.; Morandin, M.; Morawski, P.; Mordà, A.; Morello, M. J.; Moron, J.; Morris, A. B.; Mountain, R.; Muheim, F.; Müller, D.; Müller, J.; Müller, K.; Müller, V.; Mussini, M.; Muster, B.; Naik, P.; Nakada, T.; Nandakumar, R.; Nandi, A.; Nasteva, I.; Needham, M.; Neri, N.; Neubert, S.; Neufeld, N.; Neuner, M.; Nguyen, A. D.; Nguyen, T. D.; Nguyen-Mau, C.; Niess, V.; Niet, R.; Nikitin, N.; Nikodem, T.; Novoselov, A.; O'Hanlon, D. P.; Oblakowska-Mucha, A.; Obraztsov, V.; Ogilvy, S.; Okhrimenko, O.; Oldeman, R.; Onderwater, C. J. G.; Osorio Rodrigues, B.; Otalora Goicochea, J. M.; Otto, A.; Owen, P.; Oyanguren, A.; Palano, A.; Palombo, F.; Palutan, M.; Panman, J.; Papanestis, A.; Pappagallo, M.; Pappalardo, L. L.; Pappenheimer, C.; Parkes, C.; Passaleva, G.; Patel, G. D.; Patel, M.; Patrignani, C.; Pearce, A.; Pellegrino, A.; Penso, G.; Pepe Altarelli, M.; Perazzini, S.; Perret, P.; Pescatore, L.; Petridis, K.; Petrolini, A.; Petruzzo, M.; Picatoste Olloqui, E.; Pietrzyk, B.; Pilař, T.; Pinci, D.; Pistone, A.; Piucci, A.; Playfer, S.; Plo Casasus, M.; Poikela, T.; Polci, F.; Poluektov, A.; Polyakov, I.; Polycarpo, E.; Popov, A.; Popov, D.; Popovici, B.; Potterat, C.; Price, E.; Price, J. D.; Prisciandaro, J.; Pritchard, A.; Prouve, C.; Pugatch, V.; Puig Navarro, A.; Punzi, G.; Qian, W.; Quagliani, R.; Rachwal, B.; Rademacker, J. H.; Rama, M.; Rangel, M. S.; Raniuk, I.; Rauschmayr, N.; Raven, G.; Redi, F.; Reichert, S.; Reid, M. M.; dos Reis, A. C.; Ricciardi, S.; Richards, S.; Rihl, M.; Rinnert, K.; Rives Molina, V.; Robbe, P.; Rodrigues, A. B.; Rodrigues, E.; Rodriguez Lopez, J. A.; Rodriguez Perez, P.; Roiser, S.; Romanovsky, V.; Romero Vidal, A.; Ronayne, J. W.; Rotondo, M.; Rouvinet, J.; Ruf, T.; Ruiz Valls, P.; Saborido Silva, J. J.; Sagidova, N.; Sail, P.; Saitta, B.; Salustino Guimaraes, V.; Sanchez Mayordomo, C.; Sanmartin Sedes, B.; Santacesaria, R.; Santamarina Rios, C.; Santimaria, M.; Santovetti, E.; Sarti, A.; Satriano, C.; Satta, A.; Saunders, D. M.; Savrina, D.; Schiller, M.; Schindler, H.; Schlupp, M.; Schmelling, M.; Schmelzer, T.; Schmidt, B.; Schneider, O.; Schopper, A.; Schubiger, M.; Schune, M.-H.; Schwemmer, R.; Sciascia, B.; Sciubba, A.; Semennikov, A.; Serra, N.; Serrano, J.; Sestini, L.; Seyfert, P.; Shapkin, M.; Shapoval, I.; Shcheglov, Y.; Shears, T.; Shekhtman, L.; Shevchenko, V.; Shires, A.; Siddi, B. G.; Silva Coutinho, R.; Silva de Oliveira, L.; Simi, G.; Sirendi, M.; Skidmore, N.; Skwarnicki, T.; Smith, E.; Smith, E.; Smith, I. T.; Smith, J.; Smith, M.; Snoek, H.; Sokoloff, M. D.; Soler, F. J. P.; Soomro, F.; Souza, D.; Souza De Paula, B.; Spaan, B.; Spradlin, P.; Sridharan, S.; Stagni, F.; Stahl, M.; Stahl, S.; Stefkova, S.; Steinkamp, O.; Stenyakin, O.; Stevenson, S.; Stoica, S.; Stone, S.; Storaci, B.; Stracka, S.; Straticiuc, M.; Straumann, U.; Sun, L.; Sutcliffe, W.; Swientek, K.; Swientek, S.; Syropoulos, V.; Szczekowski, M.; Szczypka, P.; Szumlak, T.; T'Jampens, S.; Tayduganov, A.; Tekampe, T.; Teklishyn, M.; Tellarini, G.; Teubert, F.; Thomas, C.; Thomas, E.; van Tilburg, J.; Tisserand, V.; Tobin, M.; Todd, J.; Tolk, S.; Tomassetti, L.; Tonelli, D.; Topp-Joergensen, S.; Torr, N.; Tournefier, E.; Tourneur, S.; Trabelsi, K.; Tran, M. T.; Tresch, M.; Trisovic, A.; Tsaregorodtsev, A.; Tsopelas, P.; Tuning, N.; Ukleja, A.; Ustyuzhanin, A.; Uwer, U.; Vacca, C.; Vagnoni, V.; Valenti, G.; Vallier, A.; Vazquez Gomez, R.; Vazquez Regueiro, P.; Vázquez Sierra, C.; Vecchi, S.; Velthuis, J. J.; Veltri, M.; Veneziano, G.; Vesterinen, M.; Viaud, B.; Vieira, D.; Vieites Diaz, M.; Vilasis-Cardona, X.; Volkov, V.; Vollhardt, A.; Volyanskyy, D.; Voong, D.; Vorobyev, A.; Vorobyev, V.; Voß, C.; de Vries, J. A.; Waldi, R.; Wallace, C.; Wallace, R.; Walsh, J.; Wandernoth, S.; Wang, J.; Ward, D. R.; Watson, N. K.; Websdale, D.; Weiden, A.; Whitehead, M.; Wilkinson, G.; Wilkinson, M.; Williams, M.; Williams, M. P.; Williams, M.; Williams, T.; Wilson, F. F.; Wimberley, J.; Wishahi, J.; Wislicki, W.; Witek, M.; Wormser, G.; Wotton, S. A.; Wright, S.; Wyllie, K.; Xie, Y.; Xu, Z.; Yang, Z.; Yu, J.; Yuan, X.; Yushchenko, O.; Zangoli, M.; Zavertyaev, M.; Zhang, L.; Zhang, Y.; Zhelezov, A.; Zhokhov, A.; Zhong, L.; Zucchelli, S.

    2015-11-01

    The first measurement of CP asymmetries in the decay {B}_s^0to J/ψ {overline{K}}^{ast }{(892)}^0 and an updated measurement of its branching fraction and polarisation fractions are presented. The results are obtained using data corresponding to an integrated luminosity of 3 .0 fb -1 of proton-proton collisions recorded with the LHCb detector at centre-of-mass energies of 7 and 8 TeV. Together with constraints from B 0 → J/ψ ρ 0, the results are used to constrain additional contributions due to penguin diagrams in the CP -violating phase ϕ s , measured through B s 0 decays to charmonium. [Figure not available: see fulltext.

  5. Perceptions of patient provider agreements

    PubMed Central

    Albrecht, Jennifer S.; Khokhar, Bilal; Pradel, Françoise; Campbell, Michelle; Palmer, Jacqueline; Harris, Ilene; Palumbo, Francis

    2016-01-01

    Objectives Use of patient provider agreements (PPAs) is increasing, yet there is limited evidence on the effectiveness of PPAs to prevent prescription opioid misuse and diversion, and few guidelines for providers. We conducted eight focus groups to understand patient and prescriber perceptions of PPAs. Methods We recruited 40 patients who had been asked to sign a PPA and 40 prescribers who had administered at least one PPA. We developed topic guides for the two groups based on prior literature. Focus groups were audio-recorded and transcribed verbatim. Two investigators independently performed the content analysis of the transcripts and reached consensus on recurring themes. Key findings PPA use varied according to physician specialty. General practitioners used PPAs the least but reported increasing pressure from liability insurers to use them. Many patients reported signing a PPA in the emergency room of a hospital. Prescribers and patients reported a lack of understanding among patients concerning the purpose and content of the PPA. Prescribers questioned the legal status of the PPA, while patients believed that the PPA was a legal document intended to protect prescribers. Patients and prescribers valued PPA content items differently, although both groups agreed that signing a PPA would not prevent opioid misuse. Conclusions We identified several themes concerning the administration, content, effectiveness and utility of PPAs that highlight areas of research to improve PPAs. We also describe trends requiring further investigation. Understanding content of importance to patients will facilitate the development of a patient-centred PPA. PMID:27293486

  6. Monitoring of Biomedical License Agreements

    PubMed Central

    Keller, George H.; Ferguson, Steven M.; Pan, Percy

    2009-01-01

    Because technology licensed from research organizations can play a significant role in drug innovation and the generation of novel biomedical products, licensee performance under such agreements must be effectively monitored. This is necessary so that resultant benefits, including public health improvement, may be returned to the innovator(s) as well as society at large. The tasks that comprise monitoring are varied, but all come under the general heading of ‘enforcement of license provisions’. Since 1996, the license monitoring and enforcement program established by the US National Institutes of Health (NIH) Group has collected about $US17 million in unpaid and underpaid license royalties through formal financial audits and other investigative activities. During the same period, the Office of Technology Transfer (OTT) settled more than 60 cases of suspected patent infringement, generating around 60 new licenses and collected both back and ongoing royalties. As these numbers show, an active and effective monitoring program is an essential part of any technology transfer or biomedical licensing program. PMID:19960074

  7. Elevated Preoperative Serum Alanine Aminotransferase/Aspartate Aminotransferase (ALT/AST) Ratio Is Associated with Better Prognosis in Patients Undergoing Curative Treatment for Gastric Adenocarcinoma

    PubMed Central

    Chen, Shu-Lin; Li, Jian-Pei; Li, Lin-Fang; Zeng, Tao; He, Xia

    2016-01-01

    The level of anine aminotransferase/aspartate aminotransferase (ALT/AST) ratio in the serum was often used to assess liver injury. Whether the ALT/AST ratio (LSR) was associated with prognosis for gastric adenocarcinoma (GA) has not been reported in the literature. Our aim was to investigate the prognostic value of the preoperative LSR in patients with GA. A retrospective study was performed in 231 patients with GA undergoing curative resection. The medical records collected include clinical information and laboratory results. We investigated the correlations between the preoperative LSR and overall survival (OS). Survival analysis was conducted with the Kaplan–Meier method, and Cox regression analysis was used to determine significant independent prognostic factors for predicting survival. A p value of <0.05 was considered to be statistically significant. A total of 231 patients were finally enrolled. The median overall survival was 47 months. Multivariate analysis indicated that preoperative LSR was an independent prognostic factor in GA. Patients with LSR ≤ 0.80 had a greater risk of death than those with LSR > 0.80. The LSR was independently associated with OS in patients with GA (hazard ratio: 0.610; 95% confidence interval: 0.388–0.958; p = 0.032), along with tumor stages (hazard ratio: 3.118; 95% confidence interval: 2.044–4.756; p < 0.001) and distant metastases (hazard ratio: 1.957; 95% confidence interval: 1.119–3.422; p = 0.019). Our study first established a connection between the preoperative LSR and patients undergoing curative resection for GA, suggesting that LSR was a simple, inexpensive, and easily measurable marker as a prognostic factor, and may help to identify high-risk patients for treatment decisions. PMID:27294917

  8. 14 CFR 437.35 - Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... TRANSPORTATION LICENSING EXPERIMENTAL PERMITS Requirements to Obtain an Experimental Permit Operational Safety Documentation § 437.35 Agreements. An applicant must enter into the agreements required by § 437.63, and...

  9. 14 CFR 437.35 - Agreements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... TRANSPORTATION LICENSING EXPERIMENTAL PERMITS Requirements to Obtain an Experimental Permit Operational Safety Documentation § 437.35 Agreements. An applicant must enter into the agreements required by § 437.63, and...

  10. 75 FR 61757 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-06

    ....: 012071-001. Title: APL/Hanjin Reciprocal Space Charter Agreement. Parties: American President Lines, Ltd... Agreement. Parties: Eagle Marine Services, Ltd.; Ports of America Outer Harbor Terminal, LLC; Port...

  11. 75 FR 150 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-04

    ... the members to address issues relating to environmental initiatives and the reduction of air and water pollution. Agreement No.: 012008-004. Title: The 360 Quality Association Agreement. Parties: NYKCool AB...

  12. 76 FR 12962 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-09

    ....gov . Agreement No.: 011885-002. Title: CMA CGM/MSC Reciprocal Space Charter, Sailing and Cooperative... Coast Two-Loop Space Charter, Sailing and Cooperative Working Agreement. Parties: A.P. Moller-Maersk...

  13. 37 CFR 42.409 - Settlement agreements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... OF COMMERCE TRIAL PRACTICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Derivation After Institution of Derivation Proceeding § 42.409 Settlement agreements. An agreement or understanding under 35 U.S.C. 135(e)...

  14. 75 FR 31438 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-03

    ... Lines Joint Service Agreement. Filing Party: Tara L. Leiter, Esq.; Blank Rome, LLP; Watergate; 600 New... Service Agreement. Filing Party: Tara L. Leiter, Esq.; Blank Rome, LLP; Watergate; 600 New...

  15. 47 CFR 51.303 - Preexisting agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) INTERCONNECTION... interconnection agreements between an incumbent LEC and a telecommunications carrier, including those negotiated... approval pursuant to section 252(e) of the Act. (b) Interconnection agreements negotiated before February...

  16. 77 FR 71001 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-28

    ..., updates both parties address, and various other changes. Agreement No.: 012187-000. Title: Siem Car Carrier Pacific AS/Hoegh Autoliners, Inc. Space Charter Agreement. Parties: Siem Car Carrier Pacific...

  17. 32 CFR 37.1260 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Definitions of Terms Used in This Part § 37.1260 Cooperative... the cooperative agreement. The term does not include “cooperative research and development...

  18. 77 FR 1689 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-11

    ... . Agreement No.: 012150. Title: COSCON/POS Space Charter and Sailing Agreement. Parties: COSCO Container Lines... COSCO to charter space to Hainan POS in the trade between U.S. West Coast ports and ports in China...

  19. 75 FR 20849 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-21

    .... Agreement No.: 011075-073. Title: Central America Discussion Agreement. Parties: APL Co. PTE Ltd.; Crowley Latin America Services, LLC.; Dole Ocean Cargo Express; Great White Fleet; King Ocean Services...

  20. Legal issues critical in software license agreements.

    PubMed

    Manfredi, M J; Peterson, D M

    1989-05-01

    The complex legal aspects of software license agreements are addressed in this final part of a three-part series. A healthcare organization that has selected a software vendor and has reviewed the central provisions of a licensing agreement must then take a close look at the other provisions of the agreement. These include numerous legal provisions, regulatory requirements, and ancillary agreements related to maintenance and access to the software.

  1. 34 CFR 84.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Cooperative agreement. 84.620 Section 84.620 Education Office of the Secretary, Department of Education GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 84.620 Cooperative agreement. Cooperative agreement means an award...

  2. 23 CFR 633.206 - Project agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Project agreements. 633.206 Section 633.206 Highways... CONTRACT PROVISIONS Federal-Aid Contracts (Appalachian Contracts) § 633.206 Project agreements. (a) Project agreements executed for projects under the Appalachian program shall contain the following paragraphs:...

  3. 23 CFR 633.206 - Project agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Project agreements. 633.206 Section 633.206 Highways... CONTRACT PROVISIONS Federal-Aid Contracts (Appalachian Contracts) § 633.206 Project agreements. (a) Project agreements executed for projects under the Appalachian program shall contain the following paragraphs:...

  4. 23 CFR 633.206 - Project agreements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Project agreements. 633.206 Section 633.206 Highways... CONTRACT PROVISIONS Federal-Aid Contracts (Appalachian Contracts) § 633.206 Project agreements. (a) Project agreements executed for projects under the Appalachian program shall contain the following paragraphs:...

  5. 23 CFR 633.206 - Project agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Project agreements. 633.206 Section 633.206 Highways... CONTRACT PROVISIONS Federal-Aid Contracts (Appalachian Contracts) § 633.206 Project agreements. (a) Project agreements executed for projects under the Appalachian program shall contain the following paragraphs:...

  6. 19 CFR 118.3 - Written agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false Written agreement. 118.3 Section 118.3 Customs... CENTRALIZED EXAMINATION STATIONS General Provisions § 118.3 Written agreement. The applicant tentatively selected to operate a CES must sign a written agreement with CBP before commencing operations. Failure...

  7. 5 CFR 370.105 - Written agreements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Written agreements. 370.105 Section 370... TECHNOLOGY EXCHANGE PROGRAM § 370.105 Written agreements. Before the detail begins, the agency and private sector organization must enter into a written agreement with the individual(s) detailed. The...

  8. 19 CFR 118.3 - Written agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Written agreement. 118.3 Section 118.3 Customs... CENTRALIZED EXAMINATION STATIONS General Provisions § 118.3 Written agreement. The applicant tentatively selected to operate a CES must sign a written agreement with CBP before commencing operations. Failure...

  9. 5 CFR 370.105 - Written agreements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Written agreements. 370.105 Section 370... TECHNOLOGY EXCHANGE PROGRAM § 370.105 Written agreements. Before the detail begins, the agency and private sector organization must enter into a written agreement with the individual(s) detailed. The...

  10. 19 CFR 118.3 - Written agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false Written agreement. 118.3 Section 118.3 Customs... CENTRALIZED EXAMINATION STATIONS General Provisions § 118.3 Written agreement. The applicant tentatively selected to operate a CES must sign a written agreement with CBP before commencing operations. Failure...

  11. 19 CFR 118.3 - Written agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false Written agreement. 118.3 Section 118.3 Customs... CENTRALIZED EXAMINATION STATIONS General Provisions § 118.3 Written agreement. The applicant tentatively selected to operate a CES must sign a written agreement with CBP before commencing operations. Failure...

  12. 5 CFR 370.105 - Written agreements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Written agreements. 370.105 Section 370... TECHNOLOGY EXCHANGE PROGRAM § 370.105 Written agreements. Before the detail begins, the agency and private sector organization must enter into a written agreement with the individual(s) detailed. The...

  13. 5 CFR 370.105 - Written agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Written agreements. 370.105 Section 370... TECHNOLOGY EXCHANGE PROGRAM § 370.105 Written agreements. Before the detail begins, the agency and private sector organization must enter into a written agreement with the individual(s) detailed. The...

  14. 78 FR 75345 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-11

    ...@fmc.gov . Agreement No.; 011314-002. Title: CSAV/Trans Global Cooperative Working Agreement. Parties: Compania Sud Americana de Vapores S.A. and Trans Global Shipping NV. Filing Party: Walter H. Lion Esq.; Mc... party Swordfish Shipping Inc. to Trans Global Shipping NV and changes the agreement's termination...

  15. 48 CFR 519.7010 - Agreement contents.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Agreement contents. 519... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS GSA Mentor-Protégé Program 519.7010 Agreement contents. The contents of the Agreement must contain: (a) Names, addresses (including facsimile, e-mail, and...

  16. 48 CFR 519.7010 - Agreement contents.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Agreement contents. 519... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS GSA Mentor-Protégé Program 519.7010 Agreement contents. The contents of the Agreement must contain: (a) Names, addresses (including facsimile, e-mail, and...

  17. 48 CFR 1819.7209 - Credit agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Credit agreements. 1819... ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7209 Credit agreements. (a) The credit permits the mentor to include the cost it expends on a mentor-protégé agreement...

  18. 48 CFR 1819.7209 - Credit agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Credit agreements. 1819... ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7209 Credit agreements. (a) The credit permits the mentor to include the cost it expends on a mentor-protégé agreement...

  19. 49 CFR 1325.2 - Credit agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Credit agreements. 1325.2 Section 1325.2... OF TRANSPORTATION (CONTINUED) CARRIER RATES AND SERVICE TERMS EXTENSION OF CREDIT TO CANDIDATES FOR FEDERAL OFFICE OR THEIR REPRESENTATIVES § 1325.2 Credit agreements. (a) All agreements to extend credit...

  20. 49 CFR 1325.2 - Credit agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Credit agreements. 1325.2 Section 1325.2... OF TRANSPORTATION (CONTINUED) CARRIER RATES AND SERVICE TERMS EXTENSION OF CREDIT TO CANDIDATES FOR FEDERAL OFFICE OR THEIR REPRESENTATIVES § 1325.2 Credit agreements. (a) All agreements to extend credit...

  1. 49 CFR 1325.2 - Credit agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Credit agreements. 1325.2 Section 1325.2... OF TRANSPORTATION (CONTINUED) CARRIER RATES AND SERVICE TERMS EXTENSION OF CREDIT TO CANDIDATES FOR FEDERAL OFFICE OR THEIR REPRESENTATIVES § 1325.2 Credit agreements. (a) All agreements to extend credit...

  2. 49 CFR 1325.2 - Credit agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Credit agreements. 1325.2 Section 1325.2... OF TRANSPORTATION (CONTINUED) CARRIER RATES AND SERVICE TERMS EXTENSION OF CREDIT TO CANDIDATES FOR FEDERAL OFFICE OR THEIR REPRESENTATIVES § 1325.2 Credit agreements. (a) All agreements to extend credit...

  3. 48 CFR 1819.7209 - Credit agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Credit agreements. 1819... ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7209 Credit agreements. (a) The credit permits the mentor to include the cost it expends on a mentor-protégé agreement...

  4. 48 CFR 1819.7209 - Credit agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Credit agreements. 1819... ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7209 Credit agreements. (a) The credit permits the mentor to include the cost it expends on a mentor-protégé agreement...

  5. 49 CFR 1325.2 - Credit agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Credit agreements. 1325.2 Section 1325.2... OF TRANSPORTATION (CONTINUED) CARRIER RATES AND SERVICE TERMS EXTENSION OF CREDIT TO CANDIDATES FOR FEDERAL OFFICE OR THEIR REPRESENTATIVES § 1325.2 Credit agreements. (a) All agreements to extend credit...

  6. 48 CFR 1819.7209 - Credit agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Credit agreements. 1819... ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7209 Credit agreements. (a) The credit permits the mentor to include the cost it expends on a mentor-protégé agreement...

  7. 77 FR 42310 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-18

    ... . Agreement No.: 012119-001. Title: Maersk Line/CMA CGM TP5 Space Charter Agreement. Parties: A.P. Moller... Glovis Co., Ltd. Space Charter Agreement. Parties: Siem Car Carrier Pacific AS; Hyundai Glovis Co., Ltd..., Japan, Philippines, Singapore, and China), and authorizes the mutual chartering of space between...

  8. 7 CFR 247.4 - Agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Agreements. 247.4 Section 247.4 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.4 Agreements. (a) What agreements are necessary for agencies to administer...

  9. 7 CFR 247.4 - Agreements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Agreements. 247.4 Section 247.4 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.4 Agreements. (a) What agreements are necessary for agencies to administer...

  10. 7 CFR 247.4 - Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Agreements. 247.4 Section 247.4 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.4 Agreements. (a) What agreements are necessary for agencies to administer...

  11. 46 CFR Sec. 3 - Standby agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false Standby agreements. Sec. 3 Section 3 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION B-CONTROL AND UTILIZATION OF PORTS FEDERAL PORT CONTROLLERS Sec. 3 Standby agreements. The Director, NSA, may negotiate the standard form of service agreement, specified...

  12. 46 CFR Sec. 3 - Standby agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false Standby agreements. Sec. 3 Section 3 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION B-CONTROL AND UTILIZATION OF PORTS FEDERAL PORT CONTROLLERS Sec. 3 Standby agreements. The Director, NSA, may negotiate the standard form of service agreement, specified...

  13. 46 CFR Sec. 3 - Standby agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Standby agreements. Sec. 3 Section 3 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION B-CONTROL AND UTILIZATION OF PORTS FEDERAL PORT CONTROLLERS Sec. 3 Standby agreements. The Director, NSA, may negotiate the standard form of service agreement, specified...

  14. 76 FR 38177 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ... space in the trade from Vietnam to U.S. West Coast. Agreement No.: 012132. Title: Crowley/King Ocean Charter and Sailing Agreement. Parties: Crowley Latin America Services, LLC and King Ocean Services..., DC 20006. Synopsis: The agreement authorizes King Ocean to charter space to Crowley in the...

  15. 77 FR 28880 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-16

    ... geographic scope of the agreement. Agreement No.: 012170. Title: Crowley/SC Line Space Charter and Sailing Agreement. Parties: Crowley Latin America Services, LLC and SC Line. Filing Party: Wayne R. Rohde, Esquire... authorizes SC Line to charter space to Crowley in the trade between the U.S. Atlantic Coast and ports...

  16. 77 FR 5013 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreements Filed The Commission hereby gives notice of the filing of the following agreements under the Shipping Act of 1984. Interested parties may submit comments on the agreements to...

  17. 77 FR 45610 - Notice of Agreement Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-01

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreement Filed The Commission hereby gives notice of the filing of the following agreement under the Shipping Act of 1984. Interested parties may submit comments on the agreement to the...

  18. 78 FR 25443 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreements Filed The Commission hereby gives notice of the filing of the following agreements under the Shipping Act of 1984. Interested parties may submit comments on the agreements to...

  19. 78 FR 23251 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-18

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreements Filed The Commission hereby gives notice of the filing of the following agreements under the Shipping Act of 1984. Interested parties may submit comments on the agreements to...

  20. 76 FR 51033 - Notice of Agreement Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-17

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreement Filed The Commission hereby gives notice of the filing of the following agreement under the Shipping Act of 1984. Interested parties may submit comments on the agreement to the...

  1. 76 FR 52954 - Notice of Agreement Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-24

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreement Filed The Commission hereby gives notice of the filing of the following agreement under the Shipping Act of 1984. Interested parties may submit comments on the agreement to the...

  2. 77 FR 40881 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-11

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreements Filed The Commission hereby gives notice of the filing of the following agreements under the Shipping Act of 1984. Interested parties may submit comments on the agreements to...

  3. 76 FR 31962 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-02

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreements Filed The Commission hereby gives notice of the filing of the following agreements under the Shipping Act of 1984. Interested parties may submit comments on the agreements to...

  4. 76 FR 34992 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-15

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreements Filed The Commission hereby gives notice of the filing of the following agreements under the Shipping Act of 1984. Interested parties may submit comments on the agreements to...

  5. 77 FR 50688 - Notice of Agreement Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreement Filed The Commission hereby gives notice of the filing of the following agreement under the Shipping Act of 1984. Interested parties may submit comments on the agreement to the...

  6. 77 FR 54911 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreements Filed The Commission hereby gives notice of the filing of the following agreements under the Shipping Act of 1984. Interested parties may submit comments on the agreements to...

  7. 78 FR 30302 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-22

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreements Filed The Commission hereby gives notice of the filing of the following agreements under the Shipping Act of 1984. Interested parties may submit comments on the agreements to...

  8. 76 FR 81933 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreements Filed The Commission hereby gives notice of the filing of the following agreements under the Shipping Act of 1984. Interested parties may submit comments on the agreements to...

  9. 46 CFR 535.404 - Agreement provisions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Agreement provisions. 535.404 Section 535.404 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AFFECTING OCEAN SHIPPING IN FOREIGN COMMERCE OCEAN COMMON CARRIER AND MARINE TERMINAL OPERATOR AGREEMENTS SUBJECT TO THE SHIPPING ACT OF 1984 Filing of Agreements §...

  10. 48 CFR 416.702 - Basic agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Basic agreements. 416.702... CONTRACT TYPES TYPES OF CONTRACTS Agreements 416.702 Basic agreements. Promptly after execution by the Government, the HCA shall furnish to the Senior Procurement Executive a copy of each basic...

  11. 48 CFR 416.702 - Basic agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Basic agreements. 416.702... CONTRACT TYPES TYPES OF CONTRACTS Agreements 416.702 Basic agreements. Promptly after execution by the Government, the HCA shall furnish to the Senior Procurement Executive a copy of each basic...

  12. 48 CFR 416.702 - Basic agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Basic agreements. 416.702... CONTRACT TYPES TYPES OF CONTRACTS Agreements 416.702 Basic agreements. Promptly after execution by the Government, the HCA shall furnish to the Senior Procurement Executive a copy of each basic...

  13. 48 CFR 416.702 - Basic agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Basic agreements. 416.702... CONTRACT TYPES TYPES OF CONTRACTS Agreements 416.702 Basic agreements. Promptly after execution by the Government, the HCA shall furnish to the Senior Procurement Executive a copy of each basic...

  14. 48 CFR 416.702 - Basic agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Basic agreements. 416.702... CONTRACT TYPES TYPES OF CONTRACTS Agreements 416.702 Basic agreements. Promptly after execution by the Government, the HCA shall furnish to the Senior Procurement Executive a copy of each basic...

  15. 48 CFR 519.7010 - Agreement contents.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Agreement contents. 519... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS GSA Mentor-Protégé Program 519.7010 Agreement contents. The contents of the Agreement must contain: (a) Names, addresses (including facsimile, e-mail, and...

  16. The Pros and Cons of Petroleum Agreements.

    ERIC Educational Resources Information Center

    Lipton, Charles J.

    1980-01-01

    A mineral agreements expert discusses the options open to tribes, from the most standard lease form to arrangements as yet untried by Indian Nations. Discussion covers 18 basic provisions for inclusion in agreements, tax considerations, and basic forms of petroleum agreements (leases, joint ventures, production sharing, and service contracts).…

  17. 5 CFR 370.105 - Written agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Written agreements. 370.105 Section 370... TECHNOLOGY EXCHANGE PROGRAM § 370.105 Written agreements. Before the detail begins, the agency and private sector organization must enter into a written agreement with the individual(s) detailed. The...

  18. 19 CFR 118.3 - Written agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Written agreement. 118.3 Section 118.3 Customs... CENTRALIZED EXAMINATION STATIONS General Provisions § 118.3 Written agreement. The applicant tentatively selected to operate a CES must sign a written agreement with Customs before commencing operations....

  19. 78 FR 35649 - Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-13

    ... Commission is noticing a recent Postal Service filing concerning an amendment to the 2013 Singapore Post... inbound market dominant services with Singapore Post Limited (2013 Agreement).\\1\\ The 2013 Agreement... Foreign Postal Operators 1 Negotiated Service Agreement (with Singapore Post Limited), June 4,...

  20. 29 CFR 102.62 - Election agreements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 2 2012-07-01 2012-07-01 false Election agreements. 102.62 Section 102.62 Labor... Act § 102.62 Election agreements. (a) Consent election agreements with final regional director determinations of post-election disputes. Where a petition has been duly filed, the employer and any...

  1. 29 CFR 102.62 - Election agreements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 2 2013-07-01 2013-07-01 false Election agreements. 102.62 Section 102.62 Labor... Act § 102.62 Election agreements. (a) Consent election agreements with final regional director determinations of post-election disputes. Where a petition has been duly filed, the employer and any...

  2. 10 CFR 607.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Cooperative agreement. 607.620 Section 607.620 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 607.620 Cooperative agreement. Cooperative agreement means an award...

  3. 75 FR 3466 - Notice of Agreement Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreement Filed The Commission hereby gives notice of the filing of the following agreement under the Shipping Act of 1984. Interested parties may submit comments on the agreement to the Secretary, Federal Maritime Commission,...

  4. 33 CFR 385.16 - Design agreements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Design agreements. 385.16 Section... Processes § 385.16 Design agreements. (a) The Corps of Engineers shall execute a design agreement with each non-Federal sponsor for the projects of the Plan prior to initiation of design activities with...

  5. 33 CFR 385.16 - Design agreements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Design agreements. 385.16 Section... Processes § 385.16 Design agreements. (a) The Corps of Engineers shall execute a design agreement with each non-Federal sponsor for the projects of the Plan prior to initiation of design activities with...

  6. 23 CFR 633.206 - Project agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Project agreements. 633.206 Section 633.206 Highways... CONTRACT PROVISIONS Federal-Aid Contracts (Appalachian Contracts) § 633.206 Project agreements. (a) Project agreements executed for projects under the Appalachian program shall contain the following paragraphs:...

  7. 23 CFR 140.606 - Project agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... projects. 1 The text of FHWA Form PR-2 is found in 23 CFR part 630, subpart C, appendix A. ... 23 Highways 1 2010-04-01 2010-04-01 false Project agreements. 140.606 Section 140.606 Highways... Reimbursement for Bond Issue Projects § 140.606 Project agreements. Project Agreements, Form PR-2, shall...

  8. 24 CFR 964.335 - Grant agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Grant agreement. 964.335 Section... § 964.335 Grant agreement. (a) General. HUD will enter into a grant agreement with the recipients of a Family Investment Centers grant which defines the legal framework for the relationship between HUD and...

  9. 24 CFR 964.215 - Grant agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Grant agreement. 964.215 Section... Grant agreement. (a) General. HUD shall enter into a grant agreement with the recipient of a technical assistance grant which defines the legal framework for the relationship between HUD and a resident council...

  10. 76 FR 76411 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-07

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreements Filed The Commission hereby gives notice of the filing of the following agreements under the Shipping Act of 1984. Interested parties may submit comments on the agreements to the Secretary, Federal Maritime Commission,...

  11. 78 FR 14546 - Notice of Agreement Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-06

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreement Filed The Commission hereby gives notice of the filing of the following agreement under the Shipping Act of 1984. Interested parties may submit comments on the agreement to the Secretary, Federal Maritime Commission,...

  12. 76 FR 54235 - Notice of Agreement Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-31

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreement Filed The Commission hereby gives notice of the filing of the following agreement under the Shipping Act of 1984. Interested parties may submit comments on the agreement to the Secretary, Federal Maritime Commission,...

  13. 49 CFR 605.14 - Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... TRANSPORTATION SCHOOL BUS OPERATIONS School Bus Agreements § 605.14 Agreement. Except as provided in § 605.11 no... entered into a written agreement that the applicant will not engage in school bus operations exclusively for the transportation of students and school personnel in competition with private school...

  14. 49 CFR 605.14 - Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... TRANSPORTATION SCHOOL BUS OPERATIONS School Bus Agreements § 605.14 Agreement. Except as provided in § 605.11 no... entered into a written agreement that the applicant will not engage in school bus operations exclusively for the transportation of students and school personnel in competition with private school...

  15. 7 CFR 1775.13 - Grant agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 12 2013-01-01 2013-01-01 false Grant agreement. 1775.13 Section 1775.13 Agriculture... (CONTINUED) TECHNICAL ASSISTANCE GRANTS Grant Application Processing § 1775.13 Grant agreement. Applicants selected for funding will complete a grant agreement, RUS Guide 1775-1, which outlines the terms...

  16. 7 CFR 1775.13 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 12 2012-01-01 2012-01-01 false Grant agreement. 1775.13 Section 1775.13 Agriculture... (CONTINUED) TECHNICAL ASSISTANCE GRANTS Grant Application Processing § 1775.13 Grant agreement. Applicants selected for funding will complete a grant agreement, RUS Guide 1775-1, which outlines the terms...

  17. 24 CFR 964.215 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Grant agreement. 964.215 Section... Grant agreement. (a) General. HUD shall enter into a grant agreement with the recipient of a technical assistance grant which defines the legal framework for the relationship between HUD and a resident council...

  18. 24 CFR 964.215 - Grant agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Grant agreement. 964.215 Section... Grant agreement. (a) General. HUD shall enter into a grant agreement with the recipient of a technical assistance grant which defines the legal framework for the relationship between HUD and a resident council...

  19. 24 CFR 964.335 - Grant agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Grant agreement. 964.335 Section... § 964.335 Grant agreement. (a) General. HUD will enter into a grant agreement with the recipients of a Family Investment Centers grant which defines the legal framework for the relationship between HUD and...

  20. 24 CFR 964.335 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Grant agreement. 964.335 Section... § 964.335 Grant agreement. (a) General. HUD will enter into a grant agreement with the recipients of a Family Investment Centers grant which defines the legal framework for the relationship between HUD and...

  1. 7 CFR 1776.10 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 12 2012-01-01 2012-01-01 false Grant agreement. 1776.10 Section 1776.10 Agriculture... (CONTINUED) HOUSEHOLD WATER WELL SYSTEM GRANT PROGRAM HWWS Grants § 1776.10 Grant agreement. (a) RUS and the... grant award. RUS will furnish the form of grant agreement. No funds awarded under this part shall...

  2. 7 CFR 1776.10 - Grant agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 12 2013-01-01 2013-01-01 false Grant agreement. 1776.10 Section 1776.10 Agriculture... (CONTINUED) HOUSEHOLD WATER WELL SYSTEM GRANT PROGRAM HWWS Grants § 1776.10 Grant agreement. (a) RUS and the... grant award. RUS will furnish the form of grant agreement. No funds awarded under this part shall...

  3. 7 CFR 946.101 - Marketing agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Marketing agreement. 946.101 Section 946.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... WASHINGTON Rules and Regulations Definitions § 946.101 Marketing agreement. Marketing agreement...

  4. 7 CFR 966.111 - Marketing Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Marketing Agreement. 966.111 Section 966.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... and Regulations Definitions § 966.111 Marketing Agreement. Marketing Agreement means...

  5. 7 CFR 917.101 - Marketing agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Marketing agreement. 917.101 Section 917.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... CALIFORNIA Rules and Regulations Definitions § 917.101 Marketing agreement. Marketing agreement...

  6. 7 CFR 946.101 - Marketing agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Marketing agreement. 946.101 Section 946.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... WASHINGTON Rules and Regulations Definitions § 946.101 Marketing agreement. Marketing agreement...

  7. 7 CFR 917.101 - Marketing agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Marketing agreement. 917.101 Section 917.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... CALIFORNIA Rules and Regulations Definitions § 917.101 Marketing agreement. Marketing agreement...

  8. 7 CFR 966.111 - Marketing Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Marketing Agreement. 966.111 Section 966.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... and Regulations Definitions § 966.111 Marketing Agreement. Marketing Agreement means...

  9. 10 CFR 611.105 - Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Agreement. 611.105 Section 611.105 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS ADVANCED TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Direct Loan Program § 611.105 Agreement. (a) Only an Agreement executed by a duly authorized...

  10. 10 CFR 611.105 - Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Agreement. 611.105 Section 611.105 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS ADVANCED TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Direct Loan Program § 611.105 Agreement. (a) Only an Agreement executed by a duly authorized...

  11. 10 CFR 611.105 - Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Agreement. 611.105 Section 611.105 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS ADVANCED TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Direct Loan Program § 611.105 Agreement. (a) Only an Agreement executed by a duly authorized...

  12. 10 CFR 611.105 - Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Agreement. 611.105 Section 611.105 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS ADVANCED TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Direct Loan Program § 611.105 Agreement. (a) Only an Agreement executed by a duly authorized...

  13. 10 CFR 611.105 - Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Agreement. 611.105 Section 611.105 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS ADVANCED TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Direct Loan Program § 611.105 Agreement. (a) Only an Agreement executed by a duly authorized...

  14. 48 CFR 519.7010 - Agreement contents.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Agreement contents. 519... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS GSA Mentor-Protégé Program 519.7010 Agreement contents. The contents of the Agreement must contain: (a) Names, addresses (including facsimile, e-mail, and...

  15. 49 CFR 605.14 - Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... entered into a written agreement that the applicant will not engage in school bus operations exclusively for the transportation of students and school personnel in competition with private school bus... TRANSPORTATION SCHOOL BUS OPERATIONS School Bus Agreements § 605.14 Agreement. Except as provided in § 605.11...

  16. 49 CFR 605.14 - Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... entered into a written agreement that the applicant will not engage in school bus operations exclusively for the transportation of students and school personnel in competition with private school bus... TRANSPORTATION SCHOOL BUS OPERATIONS School Bus Agreements § 605.14 Agreement. Except as provided in § 605.11...

  17. 49 CFR 605.14 - Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... entered into a written agreement that the applicant will not engage in school bus operations exclusively for the transportation of students and school personnel in competition with private school bus... TRANSPORTATION SCHOOL BUS OPERATIONS School Bus Agreements § 605.14 Agreement. Except as provided in § 605.11...

  18. 28 CFR 83.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Cooperative agreement. 83.620 Section 83.620 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GOVERNMENT-WIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) Definitions § 83.620 Cooperative agreement. Cooperative agreement means...

  19. 46 CFR Sec. 3 - Standby agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 8 2012-10-01 2012-10-01 false Standby agreements. Sec. 3 Section 3 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION B-CONTROL AND UTILIZATION OF PORTS FEDERAL PORT CONTROLLERS Sec. 3 Standby agreements. The Director, NSA, may negotiate the standard form of service agreement, specified...

  20. 77 FR 58140 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-19

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreements Filed The Commission hereby gives notice of the filing of the following agreements under the Shipping Act of 1984. Interested parties may submit comments on the agreements to the Secretary, Federal Maritime Commission,...

  1. 48 CFR 519.7010 - Agreement contents.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Agreement contents. 519... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS GSA Mentor-Protégé Program 519.7010 Agreement contents. The contents of the Agreement must contain: (a) Names, addresses (including facsimile, e-mail, and...

  2. 78 FR 54646 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-05

    .../America Cruise Ferries, Inc. Space Charter and Sailing Agreement. Parties: Crowley Latin America Services... America, Inc.; 6009 Bethlehem Road; Preston, MD 21655. Synopsis: The Amendment would add the U.S. Pacific.... Agreement No.: 012220. Title: Crowley/Seaboard Space Charter and Sailing Agreement. Parties: Crowley...

  3. 48 CFR 41.206 - Interagency agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CATEGORIES OF CONTRACTING ACQUISITION OF UTILITY SERVICES Acquiring Utility Services 41.206 Interagency agreements. Agencies shall use interagency agreements (e.g., consolidated purchase, joint use, or cross-service agreements) when acquiring utility service or facilities from other Government agencies and...

  4. 48 CFR 41.206 - Interagency agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... CATEGORIES OF CONTRACTING ACQUISITION OF UTILITY SERVICES Acquiring Utility Services 41.206 Interagency agreements. Agencies shall use interagency agreements (e.g., consolidated purchase, joint use, or cross-service agreements) when acquiring utility service or facilities from other Government agencies and...

  5. 7 CFR 1599.5 - Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) After FAS approves an applicant's proposal, FAS will develop an agreement in consultation with the... certain countries that will be specified in the agreement. Any violation of this provision of the... transshipment of the donated commodities to a country not specified in the agreement for as long as such...

  6. 7 CFR 1499.5 - Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... FAS approves an applicant's proposal, FAS will develop an agreement in consultation with the applicant... certain countries that will be specified in the agreement. Any violation of this provision of the... transshipment of the donated commodities to a country not specified in the agreement for as long as such...

  7. 7 CFR 966.111 - Marketing Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Marketing Agreement. 966.111 Section 966.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... and Regulations Definitions § 966.111 Marketing Agreement. Marketing Agreement means...

  8. 7 CFR 966.111 - Marketing Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Marketing Agreement. 966.111 Section 966.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... and Regulations Definitions § 966.111 Marketing Agreement. Marketing Agreement means...

  9. 7 CFR 966.111 - Marketing Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Marketing Agreement. 966.111 Section 966.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... and Regulations Definitions § 966.111 Marketing Agreement. Marketing Agreement means...

  10. 7 CFR 946.101 - Marketing agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Marketing agreement. 946.101 Section 946.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... WASHINGTON Rules and Regulations Definitions § 946.101 Marketing agreement. Marketing agreement...

  11. 7 CFR 946.101 - Marketing agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Marketing agreement. 946.101 Section 946.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... WASHINGTON Rules and Regulations Definitions § 946.101 Marketing agreement. Marketing agreement...

  12. 7 CFR 946.101 - Marketing agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Marketing agreement. 946.101 Section 946.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... WASHINGTON Rules and Regulations Definitions § 946.101 Marketing agreement. Marketing agreement...

  13. 77 FR 43599 - Notice of Agreement Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-25

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreement Filed The Commission hereby gives notice of the filing of the following agreement under the Shipping Act of 1984. Interested parties may submit comments on the agreement to the Secretary, Federal Maritime Commission,...

  14. 26 CFR 601.802 - Cooperative agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... writing by mutual agreement between the Internal Revenue Service and the program sponsor at any time... program of an eligible applicant does not warrant award of an agreement, the Internal Revenue Service may... 26 Internal Revenue 20 2010-04-01 2010-04-01 false Cooperative agreements. 601.802 Section...

  15. 7 CFR 900.109 - Mediation agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Mediation agreement. 900.109 Section 900.109 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Mediation agreement. An agreement arrived at by mediation shall not become effective until approved by...

  16. 46 CFR 298.38 - Partnership agreements and limited liability company agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Partnership agreements and limited liability company... FINANCING ASSISTANCE OBLIGATION GUARANTEES Documentation § 298.38 Partnership agreements and limited liability company agreements. Partnership and limited liability company agreements must be in form...

  17. 22 CFR 124.6 - Termination of manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Termination of manufacturing license agreements... Termination of manufacturing license agreements and technical assistance agreements. The U.S. party to a manufacturing license or a technical assistance agreement must inform the Directorate of Defense Trade...

  18. 22 CFR 124.6 - Termination of manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Termination of manufacturing license agreements... Termination of manufacturing license agreements and technical assistance agreements. The U.S. party to a manufacturing license or a technical assistance agreement must inform the Directorate of Defense Trade...

  19. 22 CFR 124.6 - Termination of manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Termination of manufacturing license agreements... Termination of manufacturing license agreements and technical assistance agreements. The U.S. party to a manufacturing license or a technical assistance agreement must inform the Directorate of Defense Trade...

  20. 22 CFR 124.6 - Termination of manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Termination of manufacturing license agreements... Termination of manufacturing license agreements and technical assistance agreements. The U.S. party to a manufacturing license or a technical assistance agreement must inform the Directorate of Defense Trade...

  1. An agreement coefficient for image comparison

    USGS Publications Warehouse

    Ji, L.; Gallo, K.

    2006-01-01

    Combination of datasets acquired from different sensor systems is necessary to construct a long time-series dataset for remotely sensed land-surface variables. Assessment of the agreement of the data derived from various sources is an important issue in understanding the data continuity through the time-series. Some traditional measures, including correlation coefficient, coefficient of determination, mean absolute error, and root mean square error, are not always optimal for evaluating the data agreement. For this reason, we developed a new agreement coefficient for comparing two different images. The agreement coefficient has the following properties: non-dimensional, bounded, symmetric, and distinguishable between systematic and unsystematic differences. The paper provides examples of agreement analyses for hypothetical data and actual remotely sensed data. The results demonstrate that the agreement coefficient does include the above properties, and therefore is a useful tool for image comparison. ?? 2006 American Society for Photogrammetry and Remote Sensing.

  2. Evaluation of the Phoenix 100 ID/AST System and NID Panel for Identification of Enterobacteriaceae, Vibrionaceae, and Commonly Isolated Nonenteric Gram-Negative Bacilli

    PubMed Central

    O'Hara, Caroline M.

    2006-01-01

    The Phoenix 100 ID/AST system (Becton Dickinson Co., Sparks, Md.) is an automated system for the identification and antimicrobial susceptibility testing of bacterial isolates. This system with its negative identification (NID) panel was evaluated for its accuracy in the identification of 507 isolates of the family Enterobacteriaceae, 57 other nonenteric gram-negative isolates that are commonly isolated in clinical microbiology laboratories, and 138 isolates of the family Vibrionaceae. All of the isolates had been characterized by using approximately 48 conventional tube biochemicals. Of the 507 isolates of the Enterobacteriaceae, 456 (89.9%) were correctly identified to the genus and species levels. The five isolates of Proteus penneri required an off-line indole test, as suggested by the system to differentiate them from Proteus vulgaris. The identifications of 20 (3.9%) isolates were correct to the genus level but incorrect at the species level. Two (0.4%) isolates were reported as “no identification.” Misidentifications to the genus and species levels occurred for 29 (5.7%) isolates of the Enterobacteriaceae. These incorrect identifications were spread over 14 different genera. The most common error was the misidentification of Salmonella species. The shortest time for a correct identification was 2 h 8 min. The longest time was 12 h 27 min, for the identification of a Serratia marcescens isolate. Of the 57 isolates of nonenteric gram-negative bacilli (Acinetobacter, Aeromonas, Burkholderia, Plesiomonas, Pseudomonas, and Stenotrophomonas spp.), 48 (84.2%) were correctly identified to the genus and species levels and 7 (12.3%) were correctly identified to the genus level but not to the species level. The average time for a correct identification was 5 h 11 min. Of the Vibrionaceae spp., 123 (89.1%) were correctly identified at the end of the initial incubation period, which averaged 4 h. Based on the findings of this study, the Phoenix 100 ID/AST system NID

  3. AST IV inhibits H₂O₂-induced human umbilical vein endothelial cell apoptosis by suppressing Nox4 expression through the TGF-β1/Smad2 pathway.

    PubMed

    Ma, Yuhong; Li, Weizu; Yin, Yanyan; Li, Weiping

    2015-06-01

    Endothelial cell apoptosis plays an important role in the pathophysiological mechanisms of vascular complications in diabetes mellitus (DM). NADPH oxidase 4 (Nox4)-dependent reactive oxygen species (ROS) aggregation is the main cause of vascular endothelial cell apoptosis. The transforming growth factor-β1 (TGF-β1)/Smad2 signaling pathway is involved in the apoptosis of several types of cells. However, the association between vascular endothelial cell apoptosis and Nox4, and the involvement of the TGF-β1/Smad2 signaling pathway in vascular endothelial cell apoptosis remain unclear. In the present study, we aimed to investigate the role of Nox4-dependent ROS production and to determine the involvement of the TGF-β1/Smad2 signaling pathway in endothelial cell apoptosis induced by oxidative stress which causes vascular injury in DM. We demonstrated that hydrogen peroxide (H2O2) increased Nox4-dependent-ROS aggregation, as well as the expression of TGF-β1, Smad2, Bax and caspase-3, decreased Bcl-2 expression and increased the apoptosis of human umbilical vein endothelial cells (HUVECs). Treatment with diphenyliodonium (DPI), a specific inhibitor of Nox4 or astragaloside IV (AST IV), a monomer located in an extract of astragaloside, decreased Nox4 expression and the levels of ROS, decreased TGF-β1 and Smad2 expression, altered the expression of apoptosis-related genes and decreased the apoptosis of HUVECs. Treatment with LY2109761, a selective inhibitor of the TGF-β1/Smad2 pathway, produced results similar to those of DPI; however, LY2109761 had no effect on Nox4 expression and ROS levels. Taken together, the findings of the present study suggest that H2O2 contributes to HUVEC apoptosis by inducing Nox4-dependent ROS aggregation and activating the TGF-β1/Smad2 signaling pathway. Our data indicate that the protective effects of AST IV against vascular endothelial cell apoptosis in DM are mainly associated with the decrease in Nox4 expression through the TGF-β1

  4. 7 CFR 3431.18 - Service agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., AND EXTENSION SERVICE, DEPARTMENT OF AGRICULTURE VETERINARY MEDICINE LOAN REPAYMENT PROGRAM Administration of the Veterinary Medicine Loan Repayment Program § 3431.18 Service agreement. (a) The...

  5. 7 CFR 1720.9 - Guarantee Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... the guarantee; (6) Limitation on acceleration of guaranteed bonds; (7) Calculation and manner of..., indemnification, multiple bond issues; (19) Governing law; (20) Notices; (21) Benefit of agreement; (22)...

  6. 7 CFR 1720.9 - Guarantee Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the guarantee; (6) Limitation on acceleration of guaranteed bonds; (7) Calculation and manner of..., indemnification, multiple bond issues; (19) Governing law; (20) Notices; (21) Benefit of agreement; (22)...

  7. 7 CFR 1720.9 - Guarantee Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... the guarantee; (6) Limitation on acceleration of guaranteed bonds; (7) Calculation and manner of..., indemnification, multiple bond issues; (19) Governing law; (20) Notices; (21) Benefit of agreement; (22)...

  8. 7 CFR 1720.9 - Guarantee Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the guarantee; (6) Limitation on acceleration of guaranteed bonds; (7) Calculation and manner of..., indemnification, multiple bond issues; (19) Governing law; (20) Notices; (21) Benefit of agreement; (22)...

  9. 7 CFR 1720.9 - Guarantee Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the guarantee; (6) Limitation on acceleration of guaranteed bonds; (7) Calculation and manner of..., indemnification, multiple bond issues; (19) Governing law; (20) Notices; (21) Benefit of agreement; (22)...

  10. 76 FR 64944 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-19

    ...: Hamburg-Sud (``HSDG''); Alianca Navegacao e Logistica Ltda. e CIA (``Alianca''); Compania Sud Americana de...-010. Title: Maritime Credit Agreement. Parties: Alianca Navegacao e Logistica Ltda. & Cia.;...

  11. Synthesis, biophysical, and pharmacological evaluation of the melanocortin agonist AST3-88: modifications of peptide backbone at Trp 7 position lead to a potent, selective, and stable ligand of the melanocortin 4 receptor (MC4R).

    PubMed

    Singh, Anamika; Dirain, Marvin L; Wilczynski, Andrzej; Chen, Chi; Gosnell, Blake A; Levine, Allen S; Edison, Arthur S; Haskell-Luevano, Carrie

    2014-10-15

    The melanocortin-3 (MC3R) and melanocortin-4 (MC4R) receptors are expressed in the brain and are implicated in the regulation of food intake and energy homeostasis. The endogenous agonist ligands for these receptors (α-, β-, γ-MSH and ACTH) are linear peptides with limited receptor subtype selectivity and metabolic stability, thus minimizing their use as probes to characterize the overlapping pharmacological and physiological functions of the melanocortin receptor subtypes. In the present study, an engineered template, in which the peptide backbone was modified by a heterocyclic reverse turn mimetic at the Trp(7) residue, was synthesized using solid phase peptide synthesis and characterized by a β-galactosidase cAMP based reporter gene assay. The functional assay identified a ∼5 nM mouse MC4R agonist (AST3-88) with more than 50-fold selectivity over the mMC3R. Biophysical studies (2D (1)H NMR spectroscopy and molecular dynamics) of AST3-88 identified a type VIII β-turn secondary structure spanning the pharmacophore domain stabilized by the intramolecular interactions between the side chains of the His and Trp residues. Enzymatic studies of AST3-88 revealed enhanced stability of AST3-88 over the α-MSH endogenous peptide in rat serum. Upon central administration of AST3-88 into rats, a decreased food intake response was observed. This is the first study to probe the in vivo physiological activity of this engineered peptide-heterocycle template. These findings advance the present knowledge of pharmacophore design for potent, selective, and metabolically stable melanocortin ligands. PMID:25141170

  12. Close linkage of a blast resistance gene, Pias(t), with a bacterial leaf blight resistance gene, Xa1-as(t), in a rice cultivar 'Asominori'.

    PubMed

    Endo, Takashi; Yamaguchi, Masayuki; Kaji, Ryota; Nakagomi, Koji; Kataoka, Tomomori; Yokogami, Narifumi; Nakamura, Toshiki; Ishikawa, Goro; Yonemaru, Jun-Ichi; Nishio, Takeshi

    2012-12-01

    It has long been known that a bacterial leaf blight-resistant line in rice obtained from a crossing using 'Asominori' as a resistant parent also has resistance to blast, but a blast resistance gene in 'Asominori' has not been investigated in detail. In the present study, a blast resistance gene in 'Asominori', tentatively named Pias(t), was revealed to be located within 162-kb region between DNA markers YX4-3 and NX4-1 on chromosome 4 and to be linked with an 'Asominori' allele of the bacterial leaf blight resistance gene Xa1, tentatively named Xa1-as(t). An 'Asominori' allele of Pias(t) was found to be dominant and difference of disease severity between lines having the 'Asominori' allele of Pias(t) and those without it was 1.2 in disease index from 0 to 10. Pias(t) was also closely linked with the Ph gene controlling phenol reaction, suggesting the possibility of successful selection of blast resistance using the phenol reaction. Since blast-resistant commercial cultivars have been developed using 'Asominori' as a parent, Pias(t) is considered to be a useful gene in rice breeding for blast resistance. PMID:23341747

  13. The Identification of Novel Diagnostic Marker Genes for the Detection of Beer Spoiling Pediococcus damnosus Strains Using the BlAst Diagnostic Gene findEr

    PubMed Central

    Schmid, Jonas; Zehe, Anja; Vogel, Rudi F.

    2016-01-01

    As the number of bacterial genomes increases dramatically, the demand for easy to use tools with transparent functionality and comprehensible output for applied comparative genomics grows as well. We present BlAst Diagnostic Gene findEr (BADGE), a tool for the rapid prediction of diagnostic marker genes (DMGs) for the differentiation of bacterial groups (e.g. pathogenic / nonpathogenic). DMG identification settings can be modified easily and installing and running BADGE does not require specific bioinformatics skills. During the BADGE run the user is informed step by step about the DMG finding process, thus making it easy to evaluate the impact of chosen settings and options. On the basis of an example with relevance for beer brewing, being one of the oldest biotechnological processes known, we show a straightforward procedure, from phenotyping, genome sequencing, assembly and annotation, up to a discriminant marker gene PCR assay, making comparative genomics a means to an end. The value and the functionality of BADGE were thoroughly examined, resulting in the successful identification and validation of an outstanding novel DMG (fabZ) for the discrimination of harmless and harmful contaminations of Pediococcus damnosus, which can be applied for spoilage risk determination in breweries. Concomitantly, we present and compare five complete P. damnosus genomes sequenced in this study, finding that the ability to produce the unwanted, spoilage associated off-flavor diacetyl is a plasmid encoded trait in this important beer spoiling species. PMID:27028007

  14. The Identification of Novel Diagnostic Marker Genes for the Detection of Beer Spoiling Pediococcus damnosus Strains Using the BlAst Diagnostic Gene findEr.

    PubMed

    Behr, Jürgen; Geissler, Andreas J; Schmid, Jonas; Zehe, Anja; Vogel, Rudi F

    2016-01-01

    As the number of bacterial genomes increases dramatically, the demand for easy to use tools with transparent functionality and comprehensible output for applied comparative genomics grows as well. We present BlAst Diagnostic Gene findEr (BADGE), a tool for the rapid prediction of diagnostic marker genes (DMGs) for the differentiation of bacterial groups (e.g. pathogenic / nonpathogenic). DMG identification settings can be modified easily and installing and running BADGE does not require specific bioinformatics skills. During the BADGE run the user is informed step by step about the DMG finding process, thus making it easy to evaluate the impact of chosen settings and options. On the basis of an example with relevance for beer brewing, being one of the oldest biotechnological processes known, we show a straightforward procedure, from phenotyping, genome sequencing, assembly and annotation, up to a discriminant marker gene PCR assay, making comparative genomics a means to an end. The value and the functionality of BADGE were thoroughly examined, resulting in the successful identification and validation of an outstanding novel DMG (fabZ) for the discrimination of harmless and harmful contaminations of Pediococcus damnosus, which can be applied for spoilage risk determination in breweries. Concomitantly, we present and compare five complete P. damnosus genomes sequenced in this study, finding that the ability to produce the unwanted, spoilage associated off-flavor diacetyl is a plasmid encoded trait in this important beer spoiling species.

  15. Molecular cloning, sequencing and expression in Escherichia coli of the capsid protein gene from rabbit haemorrhagic disease virus (Spanish isolate AST/89).

    PubMed

    Boga, J A; Casais, R; Marin, M S; Martin-Alonso, J M; Carmenes, R S; Prieto, M; Parra, F

    1994-09-01

    We describe the cloning, nucleotide sequencing and expression in Escherichia coli of the major capsid component (VP60) from the Spanish field isolate AST/89 of rabbit haemorrhagic disease virus (RHDV). The sequence of the 3'-terminal 2483 nucleotides of the genome was found to be 95.4% identical to the German RHDV strain, showing ten changes in the deduced VP60 amino acid sequence. The gene coding for this structural polypeptide has been expressed in bacteria as a beta-galactosidase fusion protein or using a T7 RNA polymerase-based system. The VP60 fusion protein showed only partial antigenic similarity with native VP60 and did not confer protective immunity. The recombinant VP60 produced in the T7 RNA polymerase-based system was antigenically similar to the viral polypeptide as determined using polyclonal and monoclonal antibodies. When used to immunize rabbits the recombinant VP60 was able to protect the animals against a lethal challenge using purified RHDV.

  16. AST Critical Propulsion and Noise Reduction Technologies for Future Commercial Subsonic Engines Area of Interest 1.0: Reliable and Affordable Control Systems

    NASA Technical Reports Server (NTRS)

    Myers, William; Winter, Steve

    2006-01-01

    The General Electric Reliable and Affordable Controls effort under the NASA Advanced Subsonic Technology (AST) Program has designed, fabricated, and tested advanced controls hardware and software to reduce emissions and improve engine safety and reliability. The original effort consisted of four elements: 1) a Hydraulic Multiplexer; 2) Active Combustor Control; 3) a Variable Displacement Vane Pump (VDVP); and 4) Intelligent Engine Control. The VDVP and Intelligent Engine Control elements were cancelled due to funding constraints and are reported here only to the state they progressed. The Hydraulic Multiplexing element developed and tested a prototype which improves reliability by combining the functionality of up to 16 solenoids and servo-valves into one component with a single electrically powered force motor. The Active Combustor Control element developed intelligent staging and control strategies for low emission combustors. This included development and tests of a Controlled Pressure Fuel Nozzle for fuel sequencing, a Fuel Multiplexer for individual fuel cup metering, and model-based control logic. Both the Hydraulic Multiplexer and Controlled Pressure Fuel Nozzle system were cleared for engine test. The Fuel Multiplexer was cleared for combustor rig test which must be followed by an engine test to achieve full maturation.

  17. The Identification of Novel Diagnostic Marker Genes for the Detection of Beer Spoiling Pediococcus damnosus Strains Using the BlAst Diagnostic Gene findEr.

    PubMed

    Behr, Jürgen; Geissler, Andreas J; Schmid, Jonas; Zehe, Anja; Vogel, Rudi F

    2016-01-01

    As the number of bacterial genomes increases dramatically, the demand for easy to use tools with transparent functionality and comprehensible output for applied comparative genomics grows as well. We present BlAst Diagnostic Gene findEr (BADGE), a tool for the rapid prediction of diagnostic marker genes (DMGs) for the differentiation of bacterial groups (e.g. pathogenic / nonpathogenic). DMG identification settings can be modified easily and installing and running BADGE does not require specific bioinformatics skills. During the BADGE run the user is informed step by step about the DMG finding process, thus making it easy to evaluate the impact of chosen settings and options. On the basis of an example with relevance for beer brewing, being one of the oldest biotechnological processes known, we show a straightforward procedure, from phenotyping, genome sequencing, assembly and annotation, up to a discriminant marker gene PCR assay, making comparative genomics a means to an end. The value and the functionality of BADGE were thoroughly examined, resulting in the successful identification and validation of an outstanding novel DMG (fabZ) for the discrimination of harmless and harmful contaminations of Pediococcus damnosus, which can be applied for spoilage risk determination in breweries. Concomitantly, we present and compare five complete P. damnosus genomes sequenced in this study, finding that the ability to produce the unwanted, spoilage associated off-flavor diacetyl is a plasmid encoded trait in this important beer spoiling species. PMID:27028007

  18. 48 CFR 49.109 - Settlement agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Settlement agreements. 49.109 Section 49.109 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS General Principles 49.109 Settlement agreements....

  19. 77 FR 33459 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-06

    .... Title: Hoegh/Liberty Middle East Space Charter Agreement. Parties: Hoegh Autoliners AS and Liberty....S. East Coast Slot Charter Agreement. Parties: Hyundai Merchant Marine Co., Ltd., Mistsui O.S.K... to/from one another on an ``as needed, as available'' basis in the trade from ports on the U.S....

  20. 14 CFR 141.26 - Training agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Training agreements. 141.26 Section 141.26... OTHER CERTIFICATED AGENCIES PILOT SCHOOLS General § 141.26 Training agreements. A training center certificated under part 142 of this chapter may provide the training, testing, and checking for pilot...

  1. 14 CFR 142.33 - Training agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Training agreements. 142.33 Section 142.33... OTHER CERTIFICATED AGENCIES TRAINING CENTERS General § 142.33 Training agreements. A pilot school certificated under part 141 of this chapter may provide training, testing, and checking for a training...

  2. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... acquisitions, including hardship acquisition and protective buying (see 23 CFR 710.503). The STD must prepare a project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on an..., donations, or other contributions applied to the project provided conditions in 23 U.S.C. 323 and 23 CFR...

  3. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... acquisitions, including hardship acquisition and protective buying (see 23 CFR 710.503). The STD must prepare a project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on an..., donations, or other contributions applied to the project provided conditions in 23 U.S.C. 323 and 23 CFR...

  4. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... acquisitions, including hardship acquisition and protective buying (see 23 CFR 710.503). The STD must prepare a project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on an..., donations, or other contributions applied to the project provided conditions in 23 U.S.C. 323 and 23 CFR...

  5. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... acquisitions, including hardship acquisition and protective buying (see 23 CFR 710.503). The STD must prepare a project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on an..., donations, or other contributions applied to the project provided conditions in 23 U.S.C. 323 and 23 CFR...

  6. 32 CFR 241.5 - Written agreements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Written agreements. 241.5 Section 241.5 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.5 Written agreements....

  7. 32 CFR 241.5 - Written agreements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Written agreements. 241.5 Section 241.5 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS... Written agreements. (a) Before an assignment begins, the head of the DoD Component, private...

  8. 32 CFR 241.5 - Written agreements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 2 2013-07-01 2013-07-01 false Written agreements. 241.5 Section 241.5 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.5 Written agreements....

  9. 32 CFR 241.5 - Written agreements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Written agreements. 241.5 Section 241.5 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.5 Written agreements....

  10. 48 CFR 1819.7206 - Agreement contents.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Agreement contents. 1819.7206 Section 1819.7206 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... contents. Each mentor-protégé agreement will contain the following elements: (a) The name, address,...

  11. 48 CFR 1819.7206 - Agreement contents.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Agreement contents. 1819.7206 Section 1819.7206 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... contents. Each mentor-protégé agreement will contain the following elements: (a) The name, address,...

  12. 77 FR 32115 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    .... Title: CMA CGM/SSL Puerto Rico-Leeward Islands Space Charter Agreement. Parties: CMA CGM S.A. and Sea Star Line LLC. Filing Party: Wayne R. Rohde, Esquire; Cozen O'Connor; 1627 I Street NW., Suite 1100; Washington, DC 20006-4007. Synopsis: The agreement authorizes CMA to charter space to Sea Star in the...

  13. 39 CFR 963.12 - Settlement agreements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 39 Postal Service 1 2012-07-01 2012-07-01 false Settlement agreements. 963.12 Section 963.12 Postal Service UNITED STATES POSTAL SERVICE PROCEDURES RULES OF PRACTICE IN PROCEEDINGS RELATIVE TO... rules do not preclude the disposition of any matter by agreement between the parties at any stage of...

  14. 39 CFR 963.12 - Settlement agreements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 39 Postal Service 1 2014-07-01 2014-07-01 false Settlement agreements. 963.12 Section 963.12 Postal Service UNITED STATES POSTAL SERVICE PROCEDURES RULES OF PRACTICE IN PROCEEDINGS RELATIVE TO... rules do not preclude the disposition of any matter by agreement between the parties at any stage of...

  15. 7 CFR 1424.5 - Agreement process.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... basis. (b) Sign-up each FY will be held for 30 calendar days beginning for: (1) FY 2003 on the date of... participate, an eligible producer must submit a signed agreement during the FY sign-up period. Agreements may... production estimate reports during each applicable FY sign-up period. Such reports must comply with the...

  16. Your EHR license agreement: critical issues.

    PubMed

    Shay, Daniel F

    2014-01-01

    This article discusses several key provisions and concepts in software license agreements for electronic health records. It offers insight into what physician practices can expect to find in their license agreements, as well as practical advice on beneficial provisions. The article examines contractual language relating to term and termination, technical specifications and support, and compliance with governmental programs. PMID:25241452

  17. 40 CFR 2.215 - Confidentiality agreements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Confidentiality of Business Information § 2.215 Confidentiality agreements. (a) No EPA officer, employee, contractor, or subcontractor shall enter into any agreement with any affected business to keep business..., contractor, or subcontractor shall promise any affected business that business information will be...

  18. 34 CFR 675.48 - Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., DEPARTMENT OF EDUCATION FEDERAL WORK-STUDY PROGRAMS Work-Colleges Program § 675.48 Agreement. To participate in the Work-Colleges program, an institution shall enter into an agreement with the Secretary. The... that it satisfies the definition of “work-college” in § 675.41(a); (c) Assure that it will match...

  19. 46 CFR 535.201 - Subject agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Subject agreements. 535.201 Section 535.201 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AFFECTING OCEAN SHIPPING IN FOREIGN COMMERCE OCEAN COMMON CARRIER AND MARINE TERMINAL OPERATOR AGREEMENTS SUBJECT TO THE SHIPPING ACT OF 1984 Scope § 535.201...

  20. 7 CFR 1424.5 - Agreement process.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Agreement process. 1424.5 Section 1424.5 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOENERGY PROGRAM § 1424.5 Agreement process. (a)...

  1. 7 CFR 1424.5 - Agreement process.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Agreement process. 1424.5 Section 1424.5 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOENERGY PROGRAM § 1424.5 Agreement process. (a)...

  2. 7 CFR 1424.5 - Agreement process.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Agreement process. 1424.5 Section 1424.5 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOENERGY PROGRAM § 1424.5 Agreement process. (a)...

  3. 7 CFR 1424.5 - Agreement process.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Agreement process. 1424.5 Section 1424.5 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOENERGY PROGRAM § 1424.5 Agreement process. (a)...

  4. 26 CFR 601.802 - Cooperative agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... STATEMENT OF PROCEDURAL RULES Tax Counseling for the Elderly § 601.802 Cooperative agreements. (a) General. Tax Counseling for the Elderly programs will be administered by sponsor organizations under... agreements. If appropriations to implement the Tax Counseling for the Elderly program are received at a...

  5. 26 CFR 601.802 - Cooperative agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... STATEMENT OF PROCEDURAL RULES Tax Counseling for the Elderly § 601.802 Cooperative agreements. (a) General. Tax Counseling for the Elderly programs will be administered by sponsor organizations under... agreements. If appropriations to implement the Tax Counseling for the Elderly program are received at a...

  6. 26 CFR 601.802 - Cooperative agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... STATEMENT OF PROCEDURAL RULES Tax Counseling for the Elderly § 601.802 Cooperative agreements. (a) General. Tax Counseling for the Elderly programs will be administered by sponsor organizations under... agreements. If appropriations to implement the Tax Counseling for the Elderly program are received at a...

  7. 8 CFR 217.6 - Carrier agreements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Carrier agreements. 217.6 Section 217.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS VISA WAIVER PROGRAM § 217... may notify a carrier of the existence of a basis for termination of a carrier agreement under...

  8. 8 CFR 217.6 - Carrier agreements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Carrier agreements. 217.6 Section 217.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS VISA WAIVER PROGRAM § 217... may notify a carrier of the existence of a basis for termination of a carrier agreement under...

  9. 8 CFR 217.6 - Carrier agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Carrier agreements. 217.6 Section 217.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS VISA WAIVER PROGRAM § 217... may notify a carrier of the existence of a basis for termination of a carrier agreement under...

  10. 8 CFR 217.6 - Carrier agreements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Carrier agreements. 217.6 Section 217.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS VISA WAIVER PROGRAM § 217... may notify a carrier of the existence of a basis for termination of a carrier agreement under...

  11. 8 CFR 217.6 - Carrier agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Carrier agreements. 217.6 Section 217.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS VISA WAIVER PROGRAM § 217... may notify a carrier of the existence of a basis for termination of a carrier agreement under...

  12. 48 CFR 842.1203 - Processing agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Processing agreements. 842.1203 Section 842.1203 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS CONTRACT... submit all supporting agreements and documentation to the OGC for review as to legal sufficiency....

  13. 26 CFR 601.202 - Closing agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 20 2013-04-01 2013-04-01 false Closing agreements. 601.202 Section 601.202 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INTERNAL REVENUE PRACTICE STATEMENT OF PROCEDURAL RULES Rulings and Other Specific Matters § 601.202 Closing agreements. (a) General. (1) Under section 7121 of the...

  14. 26 CFR 601.202 - Closing agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Approval. (1) Closing agreements relating to alcohol, tobacco, and firearms, taxes in respect of any... approved by the Director, Bureau of Alcohol, Tobacco, and Firearms. (2) Closing agreements relating to... or accounts are not includable in gross income until maturity or termination, whichever...

  15. 26 CFR 601.202 - Closing agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) Approval. (1) Closing agreements relating to alcohol, tobacco, and firearms, taxes in respect of any... approved by the Director, Bureau of Alcohol, Tobacco, and Firearms. (2) Closing agreements relating to... or accounts are not includable in gross income until maturity or termination, whichever...

  16. 26 CFR 601.202 - Closing agreements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) Approval. (1) Closing agreements relating to alcohol, tobacco, and firearms, taxes in respect of any... approved by the Director, Bureau of Alcohol, Tobacco, and Firearms. (2) Closing agreements relating to... or accounts are not includable in gross income until maturity or termination, whichever...

  17. 39 CFR 963.12 - Settlement agreements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Settlement agreements. 963.12 Section 963.12 Postal Service UNITED STATES POSTAL SERVICE PROCEDURES RULES OF PRACTICE IN PROCEEDINGS RELATIVE TO VIOLATIONS OF THE PANDERING ADVERTISEMENTS STATUTE, 39 U.S.C. 3008 § 963.12 Settlement agreements....

  18. 48 CFR 1819.7206 - Agreement contents.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Agreement contents. 1819.7206 Section 1819.7206 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... contents. Each mentor-protégé agreement will contain the following elements: (a) The name, address,...

  19. 76 FR 2114 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-12

    ... Integrated Shipping Services, Ltd. Filing Party: Eric C. Jeffrey, Esq.; Goodwin Procter LLP; 901 New York...; New York Container Terminal, Inc.; and Port Newark Container Terminal LLC. Filing Party: Carol N....gov . ] Agreement No.: 011743-006. Title: Global Transportation Network Agreement. Parties: APL...

  20. 5 CFR 537.107 - Service agreements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... STUDENT LOANS § 537.107 Service agreements. (a) Before an employing agency makes any loan payments for an... period of service with the agency and to reimburse the agency for the student loan repayment benefit when... student loan repayment benefits in addition to those fixed in the agreement based on contingencies...

  1. 5 CFR 537.107 - Service agreements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... STUDENT LOANS § 537.107 Service agreements. (a) Before an employing agency makes any loan payments for an... period of service with the agency and to reimburse the agency for the student loan repayment benefit when... student loan repayment benefits in addition to those fixed in the agreement based on contingencies...

  2. 5 CFR 537.107 - Service agreements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... STUDENT LOANS § 537.107 Service agreements. (a) Before an employing agency makes any loan payments for an... period of service with the agency and to reimburse the agency for the student loan repayment benefit when... student loan repayment benefits in addition to those fixed in the agreement based on contingencies...

  3. 5 CFR 537.107 - Service agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... STUDENT LOANS § 537.107 Service agreements. (a) Before an employing agency makes any loan payments for an... period of service with the agency and to reimburse the agency for the student loan repayment benefit when... student loan repayment benefits in addition to those fixed in the agreement based on contingencies...

  4. 5 CFR 537.107 - Service agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... STUDENT LOANS § 537.107 Service agreements. (a) Before an employing agency makes any loan payments for an... period of service with the agency and to reimburse the agency for the student loan repayment benefit when... student loan repayment benefits in addition to those fixed in the agreement based on contingencies...

  5. Trade agreements on know-how discussed

    NASA Astrophysics Data System (ADS)

    Melnikov, A.

    1983-10-01

    Under the conditions of the present scientific and technical revolution the thirst for possessing advanced production experience and knowledge has led to a significant increase in the number of agreements on the transmission of know-how as compared with license agreements, whose objects are patented scientific and technical achievements. As a rule, the All-Union Litsenzintorg Association concludes agreements on the transmission of know-how in the USSR. A number of other foreign trade associations also conclude such agreements. In accordance with their charters operations are performed for the transmission of know-how, when the latter form an integral part of agreements on the export or import of goods based on the products list of these associations. An analysis of the terms of agreements on the transmission of know-how shows that the rights and duties of the parties to the agreement coincide in large measure with the rights and duties of the licensor and licensee according to the license agreement.

  6. 36 CFR 222.28 - Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Management of Wild Free-Roaming Horses and Burros § 222.28 Agreements. The Chief, Forest Service, may enter into agreements as he deems necessary to further the protection, management, and control of wild free-roaming horses and burros....

  7. 36 CFR 222.68 - Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Management of Wild Free-Roaming Horses and Burros § 222.68 Agreements. The Chief, Forest Service, may enter into agreements as he deems necessary to further the protection, management, and control of wild free-roaming horses and burros....

  8. 36 CFR 222.28 - Agreements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Management of Wild Free-Roaming Horses and Burros § 222.28 Agreements. The Chief, Forest Service, may enter into agreements as he deems necessary to further the protection, management, and control of wild free-roaming horses and burros....

  9. 36 CFR 222.28 - Agreements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Management of Wild Free-Roaming Horses and Burros § 222.28 Agreements. The Chief, Forest Service, may enter into agreements as he deems necessary to further the protection, management, and control of wild free-roaming horses and burros....

  10. 36 CFR 222.68 - Agreements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Management of Wild Free-Roaming Horses and Burros § 222.68 Agreements. The Chief, Forest Service, may enter into agreements as he deems necessary to further the protection, management, and control of wild free-roaming horses and burros....

  11. Measures of Agreement for Incompletely Ranked Data.

    ERIC Educational Resources Information Center

    Iachan, Ronaldo

    1984-01-01

    Measures of agreement for ordinal-scaled data are suggested that make use of the k categories with the highest ranks. The proposed measures are applied to the Self-Directed Search in order to evaluate its agreement with self-assessment (translation ability) or with the work environment (congruence). (Author)

  12. 46 CFR 390.5 - Agreement vessels.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... in the waterborne carriage of men, materials, goods or wares; and (v) Designated in the agreement as... water-borne carriage of men, materials, goods or wares between: (i) Two points in the United States; (ii... water-borne carriage of men, materials, goods or wares; and (v) Designated in the agreement as...

  13. 78 FR 21364 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-10

    ... removes Hyundai Merchant Marine Co., Ltd from the agreement. Agreement No.: 012199. Title: NYK/Hanjin... Co., Ltd.; and Hyundai Merchant Marine Co., Ltd. Filing Party: Jacob K. Lee; NYK Line (North America... as one Party); Hapag-Lloyd AG; Hyundai Merchant Marine Co., Ltd.; Mitsui O.S.K. Lines, Ltd.;...

  14. 77 FR 48983 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ...-Lloyd AG; Hyundai Merchant Marine Co. Ltd.; Kawasaki Kisen Kaisha, Ltd.; Nippon Yusen Kaisha Line; Orient Overseas Container Line Limited; and Yangming Marine Transport Corp. Filing Party: David F. Smith... expedited review. Agreement No.: 201218. Title: Bi-State Marine Terminal Discussion Agreement....

  15. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... acquisitions, including hardship acquisition and protective buying (see 23 CFR 710.503). The STD must prepare a project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on an..., donations, or other contributions applied to the project provided conditions in 23 U.S.C. 323 and 23 CFR...

  16. 32 CFR 536.63 - Settlement agreements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Settlement agreements. 536.63 Section 536.63 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY CLAIMS AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES Investigation and Processing of Claims § 536.63 Settlement agreements. (a)...

  17. 30 CFR 725.16 - Grant agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Grant agreement. 725.16 Section 725.16 Mineral... REGULATIONS REIMBURSEMENTS TO STATES § 725.16 Grant agreement. (a) If a Director or his authorized designee approves an agency's grant application, the Director or his authorized designee shall prepare a...

  18. 23 CFR 630.112 - Agreement provisions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... appendix A to 49 CFR part 29. (5) Lobbying certification. By signing the project agreement, the STD agrees... 49 CFR part 29, subpart F. In signing the project agreement, the State is providing the certification required in appendix C to 49 CFR part 29, unless the State provides an annual certification. (4)...

  19. 18 CFR 807.3 - Administrative agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Administrative agreements. 807.3 Section 807.3 Conservation of Power and Water Resources SUSQUEHANNA RIVER BASIN COMMISSION WATER WITHDRAWAL REGISTRATION § 807.3 Administrative agreements. The Commission may complete...

  20. 18 CFR 807.3 - Administrative agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Administrative agreements. 807.3 Section 807.3 Conservation of Power and Water Resources SUSQUEHANNA RIVER BASIN COMMISSION WATER WITHDRAWAL REGISTRATION § 807.3 Administrative agreements. The Commission may complete...

  1. Your EHR license agreement: critical issues.

    PubMed

    Shay, Daniel F

    2014-01-01

    This article discusses several key provisions and concepts in software license agreements for electronic health records. It offers insight into what physician practices can expect to find in their license agreements, as well as practical advice on beneficial provisions. The article examines contractual language relating to term and termination, technical specifications and support, and compliance with governmental programs.

  2. 24 CFR 280.30 - Grant agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Grant agreement. 280.30 Section 280... DEVELOPMENT GRANT PROGRAMS NEHEMIAH HOUSING OPPORTUNITY GRANTS PROGRAM Program Operation § 280.30 Grant agreement. (a) General. The recipient's responsibilities under NHOP will be incorporated in a...

  3. 24 CFR 280.30 - Grant agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Grant agreement. 280.30 Section 280... DEVELOPMENT GRANT PROGRAMS NEHEMIAH HOUSING OPPORTUNITY GRANTS PROGRAM Program Operation § 280.30 Grant agreement. (a) General. The recipient's responsibilities under NHOP will be incorporated in a...

  4. 30 CFR 735.19 - Grant agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Grant agreement. 735.19 Section 735.19 Mineral... REGULATORY PROGRAMS FOR NON-FEDERAL AND NON-INDIAN LANDS GRANTS FOR PROGRAM DEVELOPMENT AND ADMINISTRATION AND ENFORCEMENT § 735.19 Grant agreement. (a) If the Director or his authorized designee approves...

  5. 7 CFR 1290.8 - Grant agreements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Grant agreements. 1290.8 Section 1290.8 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SPECIALTY CROP BLOCK GRANT PROGRAM § 1290.8 Grant agreements. (a) After review and approval of a grant application, AMS will enter into...

  6. 7 CFR 1291.8 - Grant agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Grant agreements. 1291.8 Section 1291.8 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SPECIALTY CROP BLOCK GRANT PROGRAM-FARM BILL § 1291.8 Grant agreements. (a) After approval of a grant application, AMS will enter into...

  7. 7 CFR 1291.8 - Grant agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Grant agreements. 1291.8 Section 1291.8 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SPECIALTY CROP BLOCK GRANT PROGRAM-FARM BILL § 1291.8 Grant agreements. (a) After approval of a grant application, AMS will enter into...

  8. 30 CFR 725.16 - Grant agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Grant agreement. 725.16 Section 725.16 Mineral... REGULATIONS REIMBURSEMENTS TO STATES § 725.16 Grant agreement. (a) If a Director or his authorized designee approves an agency's grant application, the Director or his authorized designee shall prepare a...

  9. 30 CFR 735.19 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Grant agreement. 735.19 Section 735.19 Mineral... REGULATORY PROGRAMS FOR NON-FEDERAL AND NON-INDIAN LANDS GRANTS FOR PROGRAM DEVELOPMENT AND ADMINISTRATION AND ENFORCEMENT § 735.19 Grant agreement. (a) If the Director or his authorized designee approves...

  10. 7 CFR 1290.8 - Grant agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Grant agreements. 1290.8 Section 1290.8 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SPECIALTY CROP BLOCK GRANT PROGRAM § 1290.8 Grant agreements. (a) After review and approval of a grant application, AMS will enter into...

  11. 24 CFR 280.30 - Grant agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Grant agreement. 280.30 Section 280... DEVELOPMENT GRANT PROGRAMS NEHEMIAH HOUSING OPPORTUNITY GRANTS PROGRAM Program Operation § 280.30 Grant agreement. (a) General. The recipient's responsibilities under NHOP will be incorporated in a...

  12. 30 CFR 725.16 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Grant agreement. 725.16 Section 725.16 Mineral... REGULATIONS REIMBURSEMENTS TO STATES § 725.16 Grant agreement. (a) If a Director or his authorized designee approves an agency's grant application, the Director or his authorized designee shall prepare a...

  13. 7 CFR 1291.8 - Grant agreements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Grant agreements. 1291.8 Section 1291.8 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SPECIALTY CROP BLOCK GRANT PROGRAM-FARM BILL § 1291.8 Grant agreements. (a) After approval of a grant application, AMS will enter into...

  14. 7 CFR 1290.8 - Grant agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Grant agreements. 1290.8 Section 1290.8 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SPECIALTY CROP BLOCK GRANT PROGRAM § 1290.8 Grant agreements. (a) After review and approval of a grant application, AMS will enter into...

  15. 48 CFR 1542.1203 - Processing agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MANAGEMENT CONTRACT ADMINISTRATION Novation and Change of Name Agreements 1542.1203 Processing agreements. (a... required documentary evidence. (2) Verify the accuracy of the list of contracts through the Contract... to the Director, Policy, Training and Oversight Division, and to each affected contract office....

  16. 40 CFR 35.3010 - Delegation agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Delegation agreement. 35.3010 Section 35.3010 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE... by year for the term of the delegation agreement; (6) Identify an accounting system, acceptable...

  17. 40 CFR 35.3010 - Delegation agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Delegation agreement. 35.3010 Section 35.3010 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE... by year for the term of the delegation agreement; (6) Identify an accounting system, acceptable...

  18. 40 CFR 35.3010 - Delegation agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Delegation agreement. 35.3010 Section 35.3010 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE... by year for the term of the delegation agreement; (6) Identify an accounting system, acceptable...

  19. 26 CFR 601.202 - Closing agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 20 2014-04-01 2014-04-01 false Closing agreements. 601.202 Section 601.202 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INTERNAL REVENUE PRACTICE STATEMENT OF PROCEDURAL RULES Rulings and Other Specific Matters § 601.202 Closing agreements. (a) General. (1) Under section 7121 of the...

  20. 75 FR 34138 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-16

    ... appears in the Federal Register. Copies of the agreements are available through the Commission's Web site.... Synopsis: The agreement authorizes K-Line to charter space to CSAV in the trade from Mexico to the U.S... parties to sell or exchange slots to one another in the trades between U.S. ports and ports in......

  1. 43 CFR 24.5 - International agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false International agreements. 24.5 Section 24... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.5 International agreements. (a) International conventions... shall be to recommend that the United States negotiate and accede to only those international...

  2. 13 CFR 147.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Cooperative agreement. 147.620 Section 147.620 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (NONPROCUREMENT) Definitions § 147.620 Cooperative agreement....

  3. 47 CFR 73.1650 - International agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false International agreements. 73.1650 Section 73... BROADCAST SERVICES Rules Applicable to All Broadcast Stations § 73.1650 International agreements. (a) The... international obligations and undertakings of the United States. Accordingly, all provisions in this part 73...

  4. 47 CFR 73.1650 - International agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 4 2013-10-01 2013-10-01 false International agreements. 73.1650 Section 73... BROADCAST SERVICES Rules Applicable to All Broadcast Stations § 73.1650 International agreements. (a) The... international obligations and undertakings of the United States. Accordingly, all provisions in this part 73...

  5. 43 CFR 24.5 - International agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true International agreements. 24.5 Section 24.5... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.5 International agreements. (a) International conventions... shall be to recommend that the United States negotiate and accede to only those international...

  6. 47 CFR 73.1650 - International agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 4 2014-10-01 2014-10-01 false International agreements. 73.1650 Section 73... BROADCAST SERVICES Rules Applicable to All Broadcast Stations § 73.1650 International agreements. (a) The... international obligations and undertakings of the United States. Accordingly, all provisions in this part 73...

  7. 43 CFR 24.5 - International agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false International agreements. 24.5 Section 24... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.5 International agreements. (a) International conventions... shall be to recommend that the United States negotiate and accede to only those international...

  8. 47 CFR 73.1650 - International agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false International agreements. 73.1650 Section 73... BROADCAST SERVICES Rules Applicable to All Broadcast Stations § 73.1650 International agreements. (a) The... international obligations and undertakings of the United States. Accordingly, all provisions in this part 73...

  9. 43 CFR 24.5 - International agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 1 2013-10-01 2013-10-01 false International agreements. 24.5 Section 24... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.5 International agreements. (a) International conventions... shall be to recommend that the United States negotiate and accede to only those international...

  10. 43 CFR 24.5 - International agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false International agreements. 24.5 Section 24... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.5 International agreements. (a) International conventions... shall be to recommend that the United States negotiate and accede to only those international...

  11. 48 CFR 1819.7206 - Agreement contents.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Agreement contents. 1819.7206 Section 1819.7206 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... contents. Each mentor-protégé agreement will contain the following elements: (a) The name, address,...

  12. 46 CFR 390.5 - Agreement vessels.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Agreement vessels. 390.5 Section 390.5 Shipping MARITIME... interest in an eligible agreement vessel if the party has the right to use the vessel to generate income or a right to the proceeds or a portion of the proceeds from its use even if the party does not have...

  13. 12 CFR 1807.900 - Assistance agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 7 2011-01-01 2011-01-01 false Assistance agreement. 1807.900 Section 1807.900 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY CAPITAL MAGNET FUND Terms and Conditions of Assistance § 1807.900 Assistance agreement. (a) Each Applicant...

  14. 12 CFR 1807.900 - Assistance agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 9 2012-01-01 2012-01-01 false Assistance agreement. 1807.900 Section 1807.900 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY CAPITAL MAGNET FUND Terms and Conditions of Assistance § 1807.900 Assistance agreement. (a) Each Applicant...

  15. 12 CFR 1807.900 - Assistance agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Assistance agreement. 1807.900 Section 1807.900 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY CAPITAL MAGNET FUND Terms and Conditions of Assistance § 1807.900 Assistance agreement. (a) Each...

  16. 12 CFR 1807.900 - Assistance agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 9 2013-01-01 2013-01-01 false Assistance agreement. 1807.900 Section 1807.900 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY CAPITAL MAGNET FUND Terms and Conditions of Assistance § 1807.900 Assistance agreement. (a) Each Applicant...

  17. 24 CFR 583.400 - Grant agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 3 2011-04-01 2010-04-01 true Grant agreement. 583.400 Section 583.400 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... DEVELOPMENT COMMUNITY FACILITIES SUPPORTIVE HOUSING PROGRAM Administration § 583.400 Grant agreement....

  18. 24 CFR 583.400 - Grant agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 3 2013-04-01 2013-04-01 false Grant agreement. 583.400 Section 583.400 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... DEVELOPMENT COMMUNITY FACILITIES SUPPORTIVE HOUSING PROGRAM Administration § 583.400 Grant agreement....

  19. 24 CFR 583.400 - Grant agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Grant agreement. 583.400 Section 583.400 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... DEVELOPMENT COMMUNITY FACILITIES SUPPORTIVE HOUSING PROGRAM Administration § 583.400 Grant agreement....

  20. 24 CFR 583.400 - Grant agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 3 2014-04-01 2013-04-01 true Grant agreement. 583.400 Section 583.400 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... DEVELOPMENT COMMUNITY FACILITIES SUPPORTIVE HOUSING PROGRAM Administration § 583.400 Grant agreement....

  1. Agreement between Two Independent Groups of Raters

    ERIC Educational Resources Information Center

    Vanbelle, Sophie; Albert, Adelin

    2009-01-01

    We propose a coefficient of agreement to assess the degree of concordance between two independent groups of raters classifying items on a nominal scale. This coefficient, defined on a population-based model, extends the classical Cohen's kappa coefficient for quantifying agreement between two raters. Weighted and intraclass versions of the…

  2. 7 CFR 917.101 - Marketing agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Marketing agreement. 917.101 Section 917.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE FRESH PEARS AND PEACHES GROWN...

  3. 7 CFR 917.101 - Marketing agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Marketing agreement. 917.101 Section 917.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE FRESH PEARS AND PEACHES GROWN...

  4. 7 CFR 917.101 - Marketing agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Marketing agreement. 917.101 Section 917.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE FRESH PEARS AND PEACHES GROWN...

  5. 78 FR 33864 - Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-05

    ... From the Federal Register Online via the Government Publishing Office POSTAL REGULATORY COMMISSION Negotiated Service Agreement AGENCY: Postal Regulatory Commission. ACTION: Notice. SUMMARY: The Commission is noticing a recent Postal Service filing concerning an amendment to the 2013 China Post Agreement....

  6. Cooperative monitoring of regional security agreements

    SciTech Connect

    Pregenzer, A.L.; Vannoni, M.; Biringer, K.L.

    1996-11-01

    This paper argues that cooperative monitoring plays a critical role in the implementation of regional security agreements and confidence building measures. A framework for developing cooperative monitoring options is proposed and several possibilities for relating bilateral and regional monitoring systems to international monitoring systems are discussed. Three bilateral or regional agreements are analyzed briefly to illustrate different possibilities. These examples illustrate that the relationship of regional or bilateral arms control or security agreements to international agreements depends on a number of factors: the overlap of provisions between regional and international agreements; the degree of interest in a regional agreement among the international community; efficiency in implementing the agreement; and numerous political considerations. Given the importance of regional security to the international community, regions should be encouraged to develop their own infrastructure for implementing regional arms control and other security agreements. A regional infrastructure need not preclude participation in an international regime. On the contrary, establishing regional institutions for arms control and nonproliferation could result in more proactive participation of regional parties in developing solutions for regional and international problems, thereby strengthening existing and future international regimes. Possible first steps for strengthening regional infrastructures are identified and potential technical requirements are discussed.

  7. 14 CFR 1274.207 - Extended agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Extended agreements. 1274.207 Section 1274.207 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION COOPERATIVE AGREEMENTS WITH..., period of performance and funding levels; therefore, new proposals, certifications, and...

  8. 14 CFR 1274.207 - Extended agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Extended agreements. 1274.207 Section 1274.207 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION COOPERATIVE AGREEMENTS WITH..., period of performance and funding levels; therefore, new proposals, certifications, and...

  9. 14 CFR 1274.207 - Extended agreements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Extended agreements. 1274.207 Section 1274.207 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION COOPERATIVE AGREEMENTS WITH..., period of performance and funding levels; therefore, new proposals, certifications, and...

  10. 23 CFR 635.115 - Agreement estimate.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... submitted by the STD for each force account project (see 23 CFR part 635, subpart B) when the plans and... 23 Highways 1 2010-04-01 2010-04-01 false Agreement estimate. 635.115 Section 635.115 Highways... CONSTRUCTION AND MAINTENANCE Contract Procedures § 635.115 Agreement estimate. (a) Following the award...

  11. 48 CFR 1819.7206 - Agreement contents.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Agreement contents. 1819.7206 Section 1819.7206 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... contents. Each mentor-protégé agreement will contain the following elements: (a) The name, address,...

  12. 77 FR 27227 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-09

    ... Agreement. Parties: Crowley Latin America Services, LLC and Evergreen Line Joint Service Agreement. Filing... Between Port of Houston Authority and Cosco Container Lines Americas, Inc. Parties: Port of Houston Authority and Cosco Container Lines Americas, Inc. Filing Party: Linda Henry, Esq., Port of...

  13. 30 CFR 208.9 - Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Agreements. 208.9 Section 208.9 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT SALE OF FEDERAL ROYALTY OIL General Provisions § 208.9 Agreements. (a) A purchaser must submit to MMS two...

  14. Determination of Agreement Between Laboratory Instruments.

    PubMed

    Gray, Tonya E.; Pratt, Manley C.; Cusick, Patrick K.

    1999-03-01

    The present study was conducted to illustrate the utility of Bland-Altman plots for use by our laboratory staff and other non-statisticians in assessing the agreement between values measured by using two different laboratory instruments. A high degree of agreement reflects acceptable interchangeability of equipment and minimal effect on clinical decision-making. We have summarized literature that suggests that the regression line and correlation coefficient used with regression analysis, although commonly employed, are not appropriate first choices for evaluating agreement. Using the ABL 500 Radiometer and i-STAT Portable Chemistry Analyzer, we evaluated pH, PCO2, and TCO2. Bland-Altman plots were simple to produce, were not mathematics-intensive, and provided an easily interpreted, graphical answer to the question of agreement between instruments. For purposes of clinical decision-making, the ABL and i-STAT machines were found to be in good agreement for the tests evaluated.

  15. [Innovative medicines and market access agreements].

    PubMed

    Toumi, M; Zard, J; Duvillard, R; Jommi, C

    2013-09-01

    Market Access Agreements (MAA) for drugs have emerged in response to the need to control health expenditures, as well as to the uncertainty about the true benefit of a drug. It is possible to group MAA in two types of agreements: financial agreements and outcome-based agreements. MAA is a growing trend and is shifting towards conditional access. However, the willingness to use these contracts and their implementation differ across countries, and some are still resistant to put them in place. The MAA challenges to overcome encompass the complexity of the schemes, the administrative burden and the difficulty of evaluating MAA. It is likely that these agreements might experience further evolution in the future to become a faster pathway for therapeutic innovations, at a fair price.

  16. Cooperative monitoring of regional security agreements

    SciTech Connect

    Pregenzer, A.L.; Vannoni, M.; Biringer, K.L.

    1995-08-01

    This paper argues that cooperative monitoring plays a critical role in the implementation of regional security agreements and confidence building measures. A framework for developing cooperative monitoring options is proposed and several possibilities for relating bilateral and regional monitoring systems to international monitoring systems are discussed. Three bilateral or regional agreements are analyzed briefly to illustrate different possibilities: (1) the demilitarization of the Sinai region between Israel and Egypt in the 1970s; (2) the 1991 quadripartite agreement for monitoring nuclear facilities among Brazil, Argentina, The Argentine-Brazilian Agency for Accounting and Control of Nuclear Materials and the International Atomic Energy Agency; and (3) a bilateral Open Skies agreement between Hungary and Romania in 1991. These examples illustrate that the relationship of regional or bilateral arms control or security agreements to international agreements depends on a number of factors: the overlap of provisions between regional and international agreements; the degree of interest in a regional agreement among the international community; efficiency in implementing the agreement; and numerous political considerations.Given the importance of regional security to the international community, regions should be encouraged to develop their own infrastructure for implementing regional arms control and other security agreements. A regional infrastructure need not preclude participation in an international regime. On the contrary, establishing regional institutions for arms control and nonproliferation could result in more proactive participation of regional parties in developing solutions for regional and international problems, thereby strengthening existing and future international regimes. Possible first steps for strengthening regional infrastructures are identified and potential technical requirements are discussed.

  17. 22 CFR 124.8 - Clauses required both in manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Clauses required both in manufacturing license agreements and technical assistance agreements. 124.8 Section 124.8 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS AGREEMENTS, OFF-SHORE PROCUREMENT AND OTHER DEFENSE SERVICES §...

  18. 22 CFR 124.7 - Information required in all manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Information required in all manufacturing license agreements and technical assistance agreements. 124.7 Section 124.7 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS AGREEMENTS, OFF-SHORE PROCUREMENT AND...

  19. 48 CFR 25.403 - World Trade Organization Government Procurement Agreement and Free Trade Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false World Trade Organization Government Procurement Agreement and Free Trade Agreements. 25.403 Section 25.403 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Trade Agreements 25.403 World Trade...

  20. 48 CFR 225.403 - World Trade Organization Government Procurement Agreement and Free Trade Agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false World Trade Organization... FOREIGN ACQUISITION Trade Agreements 225.403 World Trade Organization Government Procurement Agreement and Free Trade Agreements. (c) For acquisitions of supplies covered by the World Trade...

  1. 48 CFR 225.403 - World Trade Organization Government Procurement Agreement and Free Trade Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false World Trade Organization... FOREIGN ACQUISITION Trade Agreements 225.403 World Trade Organization Government Procurement Agreement and Free Trade Agreements. (c) For acquisitions of supplies covered by the World Trade...

  2. 48 CFR 225.403 - World Trade Organization Government Procurement Agreement and Free Trade Agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false World Trade Organization... FOREIGN ACQUISITION Trade Agreements 225.403 World Trade Organization Government Procurement Agreement and Free Trade Agreements. (c) For acquisitions of supplies covered by the World Trade...

  3. 48 CFR 225.403 - World Trade Organization Government Procurement Agreement and Free Trade Agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false World Trade Organization... FOREIGN ACQUISITION Trade Agreements 225.403 World Trade Organization Government Procurement Agreement and Free Trade Agreements. (c) For acquisitions of supplies covered by the World Trade...

  4. Elevated AST-to-platelet ratio index is associated with increased all-cause mortality among HIV-infected adults in Zambia

    PubMed Central

    Vinikoor, Michael J.; Sinkala, Edford; Mweemba, Aggrey; Zanolini, Arianna; Mulenga, Lloyd; Sikazwe, Izukanji; Fried, Michael W.; Eron, Joseph J.; Wandeler, Gilles; Chi, Benjamin H.

    2015-01-01

    Background and Aims We investigated the association between significant liver fibrosis, determined by AST-to-platelet ratio index (APRI), and all-cause mortality among HIV-infected patients prescribed antiretroviral therapy (ART) in Zambia Methods Among HIV-infected adults who initiated ART, we categorized baseline APRI scores according to established thresholds for significant hepatic fibrosis (APRI ≥1.5) and cirrhosis (APRI ≥2.0). Using multivariable logistic regression we identified risk factors for elevated APRI including demographic characteristics, body mass index (BMI), HIV clinical and immunologic status, and tuberculosis. In the subset tested for hepatitis B surface antigen (HBsAg), we investigated the association of hepatitis B virus co-infection with APRI score. Using Kaplan-Meier analysis and Cox proportional hazards regression we determined the association of elevated APRI with death during ART. Results Among 20,308 adults in the analysis cohort, 1,027 (5.1%) had significant liver fibrosis at ART initiation including 616 (3.0%) with cirrhosis. Risk factors for significant fibrosis or cirrhosis included male sex, BMI <18, WHO clinical stage 3 or 4, CD4+ count <200 cells/mm3, and tuberculosis. Among the 237 (1.2%) who were tested, HBsAg-positive patients had four times the odds (adjusted odds ratio, 4.15; 95% CI, 1.71–10.04) of significant fibrosis compared HBsAg-negatives. Both significant fibrosis (adjusted hazard ratio 1.41, 95% CI, 1.21–1.64) and cirrhosis (adjusted hazard ratio 1.57, 95% CI, 1.31–1.89) were associated with increased all-cause mortality. Conclusion Liver fibrosis may be a risk factor for mortality during ART among HIV-infected individuals in Africa. APRI is an inexpensive and potentially useful test for liver fibrosis in resource-constrained settings. PMID:25581487

  5. 78 FR 78956 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... on vessels operated by one another in the trade from the U.S. East and Gulf Coasts to ports in the Caribbean, South America, Central America, Mediterranean, and Middle East. Agreement No.: 201212-001....

  6. 78 FR 59359 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-26

    ....; Tropical Shipping and Construction Company Limited; and Zim Integrated Shipping Services, Ltd. Filing Party... Company Tower, 555 West Fifth Street 46th Floor, Los Angeles, CA 90013. Synopsis: The agreement...

  7. Appendix G: Peer review nondisclosure agreement

    SciTech Connect

    None, None

    2009-01-18

    This peer review nondisclosure agreement should be signed by each reviewer prior to the program sending review materials if sensitive or proprietary information will be provided reviewers or discussed during the review, and to everyone attending a review.

  8. 77 FR 68121 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-15

    ... trade between Puerto Rico and the Dominican Republic. Agreement No.: 012186. Title: Crowley/Priority Ro... trade between Puerto Rico and the Dominican Republic for cargo originating in Puerto Rico as well as...

  9. Quick Guide: Power Purchase Agreements (Fact Sheet)

    SciTech Connect

    Not Available

    2010-06-01

    Introduction to Federal power purchase agreements (PPAs), including available FEMP services and technical assistance as well as questions to ask when evaluating PPAs for a Federal renewable energy project.

  10. 77 FR 65886 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-31

    ... Lines, Ltd. and Crowley Liner Services/Crowley Caribbean Services, LLC as parties to the agreement... amendment reflects the resignation of Bernuth Lines, Ltd. and Crowley Liner Services, Inc./Crowley...

  11. 24 CFR 700.140 - Participatory agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... agreement. (a) Before actual acceptance into CHSP, potential participants must work with the PAC and the... accepting any of the services under the case plan. (b) Once the plan is approved by the PAC and the...

  12. 7 CFR 1944.259 - Participatory agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... agreement. (a) Before actual acceptance into CHSP, potential participants must work with the PAC and the... accepting any of the services under the case plan. (b) Once the plan is approved by the PAC and the...

  13. 24 CFR 700.140 - Participatory agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... agreement. (a) Before actual acceptance into CHSP, potential participants must work with the PAC and the... accepting any of the services under the case plan. (b) Once the plan is approved by the PAC and the...

  14. 7 CFR 1944.259 - Participatory agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... agreement. (a) Before actual acceptance into CHSP, potential participants must work with the PAC and the... accepting any of the services under the case plan. (b) Once the plan is approved by the PAC and the...

  15. 32 CFR 1656.8 - Employment agreements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM ALTERNATIVE..., Selective Service and the employer shall enter into an employment agreement that specifies their respective duties and responsibilities under the Alternative Service Program. (b) Restrictions on Selective...

  16. 32 CFR 1656.8 - Employment agreements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM ALTERNATIVE..., Selective Service and the employer shall enter into an employment agreement that specifies their respective duties and responsibilities under the Alternative Service Program. (b) Restrictions on Selective...

  17. 32 CFR 1656.8 - Employment agreements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM ALTERNATIVE..., Selective Service and the employer shall enter into an employment agreement that specifies their respective duties and responsibilities under the Alternative Service Program. (b) Restrictions on Selective...

  18. 32 CFR 1656.8 - Employment agreements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM ALTERNATIVE..., Selective Service and the employer shall enter into an employment agreement that specifies their respective duties and responsibilities under the Alternative Service Program. (b) Restrictions on Selective...

  19. 32 CFR 1656.8 - Employment agreements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM ALTERNATIVE..., Selective Service and the employer shall enter into an employment agreement that specifies their respective duties and responsibilities under the Alternative Service Program. (b) Restrictions on Selective...

  20. 14 CFR 420.31 - Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Airmen prior to a launch and for closing of air routes during the launch window and other such measures... shall complete an agreement with the FAA Air Traffic Control (ATC) office having jurisdiction over...

  1. 77 FR 72349 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-05

    ... & Logistic GMBH & Co. KG; Industrial Maritime Carriers LLC; Seaboard Marine, Ltd.; and West Coast Industrial... amendment removes BBC Chartering & Logistic GMBH & Co. KG as a party to the agreement. By Order of...

  2. 24 CFR 7.43 - Settlement agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... and/or their designees; and (4) Otherwise comply with 29 CFR part 1614. (b) Any settlement agreement... Regard to Race, Color Religion, Sex, National Origin, Age, Disability or Reprisal Remedies,...

  3. 75 FR 12748 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-17

    ....: 012092. Title: MOL/``K'' Line Space Charter and Sailing Agreement. Parties: Kawasaki Kisen Kaisha, Ltd... exchange slots and to coordinate sailings in the trades between the U.S. Pacific Coast and Japan,...

  4. 77 FR 23248 - Notice of Agreement Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-18

    ....: 012164. Title: KL/WHS Space Charter and Sailing Agreement. Parties: Kawasaki Kisen Kaisha, Ltd. and Wan... Line and Wan Hai to charter space on their respective vessels, coordinate their sailings, and...

  5. 34 CFR 675.35 - Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., DEPARTMENT OF EDUCATION FEDERAL WORK-STUDY PROGRAMS Job Location and Development Program § 675.35 Agreement... institution uses Federal funds to contract with another institution, suitable performance standards will...

  6. Quick Guide: Power Purchase Agreements (Fact Sheet)

    SciTech Connect

    Not Available

    2011-07-01

    Introduction to Federal power purchase agreements (PPAs), including available FEMP services and technical assistance as well as questions to ask when evaluating PPAs for a Federal renewable energy project.

  7. 77 FR 76482 - Notice of Agreement Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-28

    ...; Evergreen Line Joint Service Agreement; Hanjin Shipping Co., Ltd.; Hapag-Lloyd AG; Hyundai Merchant Marine... Overseas Container Line Limited; Yangming Marine Transport Corp.; and Zim Integrated Shipping Services,...

  8. 75 FR 51073 - Notice of Agreement Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ...; Evergreen Line Joint Service Agreement; Gold Star Line, Ltd.; Hanjin Shipping Co., Ltd.; Hyundai Merchant Marine Co. Ltd; Kawasaki Kisen Kaisha, Ltd.; MISC Berhad; Mitsui O.S.K. lines Ltd.; Nippon Yusen...

  9. 75 FR 78245 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-15

    ... Shipping Container Lines Co. Ltd., China Shipping Container Lines (Hong Kong) Co. Ltd., and Compania Sud..., including China, Hong Kong, and Korea. Agreement No.: 012114. Title: POS/TSL Vessel Sharing...

  10. 24 CFR 7.43 - Settlement agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... and/or their designees; and (4) Otherwise comply with 29 CFR part 1614. (b) Any settlement agreement... Regard to Race, Color Religion, Sex, National Origin, Age, Disability or Reprisal Remedies,...

  11. 24 CFR 7.43 - Settlement agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... and/or their designees; and (4) Otherwise comply with 29 CFR part 1614. (b) Any settlement agreement... Regard to Race, Color Religion, Sex, National Origin, Age, Disability or Reprisal Remedies,...

  12. 24 CFR 7.43 - Settlement agreements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... and/or their designees; and (4) Otherwise comply with 29 CFR part 1614. (b) Any settlement agreement... Regard to Race, Color Religion, Sex, National Origin, Age, Disability or Reprisal Remedies,...

  13. 24 CFR 7.43 - Settlement agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... and/or their designees; and (4) Otherwise comply with 29 CFR part 1614. (b) Any settlement agreement... Regard to Race, Color Religion, Sex, National Origin, Age, Disability or Reprisal Remedies,...

  14. 78 FR 70300 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-25

    ... agreement authorizes the parties to share vessels and engage in related cooperative activities in the trades between each of Asia, North Europe, and the Mediterranean on the one hand and the U.S. on the other...

  15. 78 FR 64940 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-30

    ... agreement authorizes the parties to share vessels and engage in related cooperative activities in the trades between each of Asia, North Europe, and the Mediterranean on the one hand and the U.S. on the other...

  16. 45 CFR 1640.3 - Contractual agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OF FEDERAL LAW TO LSC RECIPIENTS § 1640.3 Contractual agreement. As a condition of receiving LSC... respect to its LSC funds, it will be subject to the Federal laws listed in § 1640.2(a)(1). The...

  17. 42 CFR 460.154 - Enrollment agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) Participant Enrollment and Disenrollment § 460.154 Enrollment agreement. If the...

  18. 75 FR 74732 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-01

    .... Slot Charter Agreement. Parties: Hainan PO Shipping Co., Ltd. and T.S. Lines Ltd. Filing Party: Neal M. Mayer, Esq.; Hoppel, Mayer & Coleman; 1050 Connecticut Avenue, NW., Tenth Floor; Washington, DC...

  19. 42 CFR 460.154 - Enrollment agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) Participant Enrollment and Disenrollment § 460.154 Enrollment agreement. If the...

  20. 42 CFR 460.154 - Enrollment agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) Participant Enrollment and Disenrollment § 460.154 Enrollment agreement. If the...

  1. 42 CFR 460.154 - Enrollment agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) Participant Enrollment and Disenrollment § 460.154 Enrollment agreement. If the...

  2. 78 FR 17234 - Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-20

    ... From the Federal Register Online via the Government Publishing Office POSTAL REGULATORY COMMISSION Negotiated Service Agreement AGENCY: Postal Regulatory Commission. ACTION: Notice SUMMARY: The Commission is noticing a recent Postal Service filing concerning an amendment to Discover Financial Services...

  3. 76 FR 28778 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-18

    ... Company Tower; 555 West Fifth Street, 46th Floor; Los Angeles, CA 90013. Synopsis: The amendment removes... coast and Guatemala and Honduras. Agreement No.: 012127. Title: Hoegh/Liberty Space Charter...

  4. 76 FR 41794 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-15

    ... Services Limited; and King Ocean Service de Venezuela, S.A. Filing Party: Wayne Rohde, Esq.; Cozen O'Connor... address of Hamburg Sud, and removes King Ocean Service de Venezuela, S.A. as a participant. Agreement...

  5. 34 CFR 675.35 - Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., DEPARTMENT OF EDUCATION FEDERAL WORK-STUDY PROGRAMS Job Location and Development Program § 675.35 Agreement... to the Secretary an annual report on the use of the funds and an evaluation of the effectiveness...

  6. 34 CFR 675.35 - Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., DEPARTMENT OF EDUCATION FEDERAL WORK-STUDY PROGRAMS Job Location and Development Program § 675.35 Agreement... to the Secretary an annual report on the use of the funds and an evaluation of the effectiveness...

  7. 34 CFR 675.35 - Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., DEPARTMENT OF EDUCATION FEDERAL WORK-STUDY PROGRAMS Job Location and Development Program § 675.35 Agreement... to the Secretary an annual report on the use of the funds and an evaluation of the effectiveness...

  8. 34 CFR 675.35 - Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., DEPARTMENT OF EDUCATION FEDERAL WORK-STUDY PROGRAMS Job Location and Development Program § 675.35 Agreement... to the Secretary an annual report on the use of the funds and an evaluation of the effectiveness...

  9. 78 FR 68444 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-14

    ... European Continent-US East Coast Service Space Charter Agreement. Parties: MSC Mediterranean Shipping... the trade between the North West European Continent and the U.S. East Coast. Dated: November 8,...

  10. Managed entry agreements for pharmaceuticals in Australia.

    PubMed

    Vitry, Agnes; Roughead, Elizabeth

    2014-09-01

    In Australia, a number of managed entry agreements have been developed to enable national coverage of new medicines. Non-outcome based agreements are usually pricing arrangements that involve price or volume rebate agreements. In February 2013, there were at least 71 special pricing arrangements in place, including 26 for medicines restricted to use in hospitals. Health outcome based agreements can be made at the individual or population level. At the individual level, there were 28 medicines funded subject to continuation rules involving documentation of adequate benefit within the individual; some of these medicines also had price agreements in place. At the population level, only one outcome-based agreement has been implemented so far, for bosentan, a medicine marketed for pulmonary hypertension. In May 2010, a memorandum of understanding signed between the Australian Government and Medicines Australia, the peak pharmaceutical industry organisation, included the possibility for industry to request consideration of a 'Managed Entry Scheme' as part of the funding submission process for medicines with high clinical needs. It includes the possibility of a randomised controlled trial (RCT)-based entry scheme. Although this form of managed entry has yet not been trialed in Australia, several 2012/2013 funding recommendations included requests by the decision making committee for further evidence development.

  11. Detection of virulence factors of Escherichia coli focused on prevalence of EAST1 toxin in stool of diarrheic and non-diarrheic piglets and presence of adhesion involving virulence factors in astA positive strains.

    PubMed

    Zajacova, Zuzana Sramkova; Konstantinova, Lucie; Alexa, Pavel

    2012-01-27

    Between 2005 and 2009, a total of 800 Escherichia coli strains isolated from piglets with diarrhea were tested for the presence of enteroaggregative heat-stable enterotoxin EAST1, heat-labile (LT) and heat-stable enterotoxins (STa) and shigatoxin (Stx2e) by PCR with the purpose of investigating the present distribution of virulence factors on swine farms in the Czech Republic. The isolates were analyzed for their O-serogroup, fimbrial (K88, K99, 987P, F41, F18) and nonfimbrial adhesins (adhesin involved in diffuse adherence AIDA and porcine attaching and effacing-associated factor PAA). The detection rates of ETEC and STEC isolates were 36.5% and 7.75%, respectively, which implies that ETEC play the major role in E. coli infections in Czech herds. Generally, the most common serotype was O149:K88 which possessed genetic determinants for LT and EAST1. None of the tested E. coli isolates was positive for genes K99, 987P and F41. It was shown that out of 800 E. coli strains isolated from pigs, 277 were EAST1 positive and 74% from the latter were identified as ETEC. Of the fimbrial adhesins, K88 and F18 were commonly detected. Over 80% of K88/EAST1 positive strains possessed the gene for paa. We detected no EAE isolate positive for fimbrial adhesins or PAA and AIDA. The AIDA was more often associated with F18 than with K88. The gene astA was also identified among E. coli isolates of non-diarrheic piglets. We tested rectal swab samples collected from apparently healthy piglets on three farms. On all farms, E. coli astA positive strains (26.66%, 90.00% and 46.66% astA positive animals) were isolated. Our results showed a significantly higher prevalence of astA positive E. coli isolates among apparently healthy piglets in comparison with diarrheic piglets. The question remains as to what is the role of the astA gene in the pathogenesis of porcine colibacillosis and as a virulence factor. PMID:21864997

  12. Clock Agreement Among Parallel Supercomputer Nodes

    DOE Data Explorer

    Jones, Terry R.; Koenig, Gregory A.

    2014-04-30

    This dataset presents measurements that quantify the clock synchronization time-agreement characteristics among several high performance computers including the current world's most powerful machine for open science, the U.S. Department of Energy's Titan machine sited at Oak Ridge National Laboratory. These ultra-fast machines derive much of their computational capability from extreme node counts (over 18000 nodes in the case of the Titan machine). Time-agreement is commonly utilized by parallel programming applications and tools, distributed programming application and tools, and system software. Our time-agreement measurements detail the degree of time variance between nodes and how that variance changes over time. The dataset includes empirical measurements and the accompanying spreadsheets.

  13. Agreement Execution Process Study: CRADAs and NF-WFO Agreements and the Speed of Business

    SciTech Connect

    Harrer, Bruce J.; Cejka, Cheryl L.; Macklin, Richard; Miksovic, Ann

    2011-02-01

    This report summarizes the findings of a study on the execution of Cooperative Research and Development Agreements (CRADAs) and Non-Federal Work for Others (NF-WFO) agreements across the U.S. Department of Energy (DOE) laboratory complex. The study provides quantitiative estimates of times required to negotiate and execute these agreements across the DOE complex. It identifies factors impacting on cycle times and describes best practicies used at various laboratories and site offices that reduce cycle times.

  14. Cooperative research and development agreements at METC

    SciTech Connect

    Ludlow, J.C.; Jarr, L.A.; Anderson, R.J.

    1995-06-01

    The Federal Technology Transfer Act of 1986 (P.L. 99-502) provided a new mechanism for joint research between private parties and the Morgantown Energy Technology Center (METC). Joint projects under this law are called Cooperative Research And Development Agreements (CRADAs) and are simply agreements between METC and the private sector to work together on a mutually beneficial project. Of primary interest to METC is the development and deployment of: (1) clean, efficient power generation technologies, (2) technologies for the characterization and exploitation of the Nation`s natural gas resource, and (3) environmental remediation technologies.

  15. An Efficient Byzantine Fault Tolerant Agreement

    NASA Astrophysics Data System (ADS)

    Saini, Poonam; Singh, Awadhesh Kumar

    2010-11-01

    Most of the distributed transaction protocols rely on atomic commitment. Dealing with arbitrary failures effectively is a major operational challenge to be faced with. In the contemporary literature, protocols such as BFTDC [3] and PBFT [5] run an effective agreement protocol. The drawback with these protocols is that they incur increased message overhead as well as latency into the protocol execution. The paper presents an efficient byzantine fault tolerant distributed commit protocol. The proposed agreement protocol helps in achieving faster execution results using an effective view change mechanism. The protocol is computationally more efficient. It has lower message complexity and reduces the time overhead incurred in transaction processing.

  16. 78 FR 66713 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-06

    ....; Tropical Shipping and Construction Company Limited; and Zim Integrated Shipping Services, Ltd. Filing Party... Container Lines Company Limited; Evergreen Line Joint Service Agreement; Hamburg-S d; Hapag-Lloyd AG; Hapag....; Mediterranean Shipping Company, S.A.; Mitsui O.S.K. Lines Ltd.; Nippon Yusen Kaisha Line; Norasia...

  17. 23 CFR 140.606 - Project agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Project agreements. 140.606 Section 140.606 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT... projects. 1 The text of FHWA Form PR-2 is found in 23 CFR part 630, subpart C, appendix A....

  18. 23 CFR 140.606 - Project agreements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Project agreements. 140.606 Section 140.606 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT... projects. 1 The text of FHWA Form PR-2 is found in 23 CFR part 630, subpart C, appendix A....

  19. 23 CFR 140.606 - Project agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Project agreements. 140.606 Section 140.606 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT... projects. 1 The text of FHWA Form PR-2 is found in 23 CFR part 630, subpart C, appendix A....

  20. 23 CFR 140.606 - Project agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Project agreements. 140.606 Section 140.606 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT... projects. 1 The text of FHWA Form PR-2 is found in 23 CFR part 630, subpart C, appendix A....