Science.gov

Sample records for agreement cba classifications

  1. AO Distal Radius Fracture Classification: Global Perspective on Observer Agreement.

    PubMed

    Jayakumar, Prakash; Teunis, Teun; Giménez, Beatriz Bravo; Verstreken, Frederik; Di Mascio, Livio; Jupiter, Jesse B

    2017-02-01

    Background The primary objective of this study was to test interobserver reliability when classifying fractures by consensus by AO types and groups among a large international group of surgeons. Secondarily, we assessed the difference in inter- and intraobserver agreement of the AO classification in relation to geographical location, level of training, and subspecialty. Methods A randomized set of radiographic and computed tomographic images from a consecutive series of 96 distal radius fractures (DRFs), treated between October 2010 and April 2013, was classified using an electronic web-based portal by an invited group of participants on two occasions. Results Interobserver reliability was substantial when classifying AO type A fractures but fair and moderate for type B and C fractures, respectively. No difference was observed by location, except for an apparent difference between participants from India and Australia classifying type B fractures. No statistically significant associations were observed comparing interobserver agreement by level of training and no differences were shown comparing subspecialties. Intra-rater reproducibility was "substantial" for fracture types and "fair" for fracture groups with no difference accounting for location, training level, or specialty. Conclusion Improved definition of reliability and reproducibility of this classification may be achieved using large international groups of raters, empowering decision making on which system to utilize. Level of Evidence Level III.

  2. Divergent Aging Characteristics in CBA/J and CBA/CaJ Mouse Cochleae

    PubMed Central

    Dahl, Ashley R.; Gagnon, Patricia M.

    2010-01-01

    Two inbred mouse strains, CBA/J and CBA/CaJ, have been used nearly interchangeably as ‘good hearing’ standards for research in hearing and deafness. We recently reported, however, that these two strains diverge after 1 year of age, such that CBA/CaJ mice show more rapid elevation of compound action potential (CAP) thresholds at high frequencies (Ohlemiller, Brain Res. 1277: 70–83, 2009). One contributor is progressive decline in endocochlear potential (EP) that appears only in CBA/CaJ. Here, we explore the cellular bases of threshold and EP disparities in old CBA/J and CBA/CaJ mice. Among the major findings, both strains exhibit a characteristic age (∼18 months in CBA/J and 24 months in CBA/CaJ) when females overtake males in sensitivity decline. Strain differences in progression of hearing loss are not due to greater hair cell loss in CBA/CaJ, but instead appear to reflect greater neuronal loss, plus more pronounced changes in the lateral wall, leading to EP decline. While both male and female CBA/CaJ show these pathologies, they are more pronounced in females. A novel feature that differed sharply by strain was moderate loss of outer sulcus cells (or ‘root’ cells) in spiral ligament of the upper basal turn in old CBA/CaJ mice, giving rise to deep indentations and void spaces in the ligament. We conclude that CBA/CaJ mice differ both quantitatively and qualitatively from CBA/J in age-related cochlear pathology, and model different types of presbycusis. PMID:20706857

  3. Agreement between cranial and facial classification through clinical observation and anthropometric measurement among envigado school children

    PubMed Central

    2014-01-01

    Background To evaluate the agreement between cranial and facial classification obtained by clinical observation and anthropometric measurements among school children from the municipality of Envigado, Colombia. Methods This cross-sectional study was carried out among 8-15-year-old children. Initially, an indirect clinical observation was made to determine the skull pattern (dolichocephalic, mesocephalic or brachycephalic), based on visual equivalence of right eurion- left eurion and glabella-opisthocranion anthropometric points, as well as the facial type (leptoprosopic, mesoprosopic and euryprosopic), according to the left and right zygomatic, nasion and gnation points. Following, a direct measurement was conducted with an anthropometer using the same landmarks for cranial width and length, as well as for facial width and height. Subsequently, both the facial index [euryprosopic (≤80.9%), mesoprosopic (between 81% - 93%) and leptoprosopic (≥93.1%)] and the cranial index [dolichocephalic (index ≤ 75.9%), mesocephalic (between 76% - 81%), and brachycephalic (≥81.1%)] were determined. Concordance between the indices obtained was calculated by direct and indirect measurement using the Kappa statistic. Results A total of 313 students were enrolled; 172 (55%) were female and 141 (45%) male. The agreement between the direct and indirect facial index measurements was 0.189 (95% CI 0.117-0261), and the cranial index was 0.388 (95% CI 0.304-0.473), indicating poor concordance. Conclusions No agreement was observed between direct measurements conducted with an anthropometer and indirect measurements via visual evaluation. Therefore, the indirect visual classification method is not appropriate to calculate the cranial and facial indices. PMID:24886038

  4. Inter-Coder Agreement in One-to-Many Classification: Fuzzy Kappa

    PubMed Central

    Kirilenko, Andrei P.; Stepchenkova, Svetlana

    2016-01-01

    Content analysis involves classification of textual, visual, or audio data. The inter-coder agreement is estimated by making two or more coders to classify the same data units, with subsequent comparison of their results. The existing methods of agreement estimation, e.g., Cohen’s kappa, require that coders place each unit of content into one and only one category (one-to-one coding) from the pre-established set of categories. However, in certain data domains (e.g., maps, photographs, databases of texts and images), this requirement seems overly restrictive. The restriction could be lifted, provided that there is a measure to calculate the inter-coder agreement in the one-to-many protocol. Building on the existing approaches to one-to-many coding in geography and biomedicine, such measure, fuzzy kappa, which is an extension of Cohen’s kappa, is proposed. It is argued that the measure is especially compatible with data from certain domains, when holistic reasoning of human coders is utilized in order to describe the data and access the meaning of communication. PMID:26933956

  5. Agreement Between Deoxyribonucleic Acid Base Composition and Taxometric Classification of Gram-Positive Cocci1

    PubMed Central

    Silvestri, L. G.; Hill, L. R.

    1965-01-01

    Silvestri, L. G. (Università Statale, Milan, Italy), and L. R. Hill. Agreement between deoxyribonucleic acid base composition and taxometric classification of gram-positive cocci. J. Bacteriol. 90:136–140. 1965.—It had been previously proposed, from taxometric analyses, that gram-positive, catalase-positive cocci be divided into two subgroups. Thirteen strains, representative of both subgroups, were examined for deoxyribonucleic acid (DNA) base composition, determined from melting temperatures. Per cent GC (guanine + cytosine/total bases) values fell into two groups: 30.8 to 36.5% GC and 69 to 75% GC. Strains with low per cent GC values belonged to the Staphylococcus aureus–S. saprophyticus–S. lactis taxometric subgroups, and those with high per cent GC values belonged to the S. roseus–S. afermentans subgroup. The hypothetical nature of any classification is emphasized, and, in the present work, the hypothesis derived from taxometric analyses of division into two subgroups is confirmed by the study of DNA base ratios. The two subgroups correspond, respectively, to the genera Staphylococcus and Micrococcus. PMID:16562008

  6. Agreement between long-term neonatal background classification by conventional and amplitude-integrated EEG.

    PubMed

    Clancy, Robert R; Dicker, Lee; Cho, Sandy; Cook, Noah; Nicolson, Susan C; Wernovsky, Gil; Spray, Thomas L; Gaynor, J William

    2011-02-01

    Conventional EEG (CEEG) in neonates is considered the gold standard for evaluating EEG background and detecting electrographic seizures. However, CEEG is expensive and cumbersome for long-term monitoring. A simplified method, amplitude-integrated EEG (AEEG) has been rapidly adopted to accomplish the same goals. The purpose of this study was to measure the agreement between the methods of classification in long-term EEG background assessments by CEEG and AEEG. Infants underwent CEEG monitoring after cardiac surgery and the background during four 12-hour epochs classified as "normal" or "mildly," "moderately," or "markedly" abnormal. CEEGs were converted to a single-channel AEEG and independently interpreted as "normal," "moderately abnormal," or "markedly abnormal" by standard amplitude criteria. The distributions of CEEG and AEEG interpretations were statistically compared, and the associations between CEEG and AEEG interpretations were measured. Generalized estimating equations were used to measure the effects of seizures and patient age on the agreement between AEEG and CEEG scores. Paired CEEGs and AEEGs were available for 637 epochs recorded from 179 infants. The distribution of CEEG backgrounds included 60% normal, 22% mildly abnormal, 13% moderately abnormal, and 5% markedly abnormal. The distribution of AEEG backgrounds was significantly different from CEEG and included 22% normal, 73% moderately abnormal, and 5% markedly abnormal. Nevertheless, the two techniques exhibited a significant, moderate positive association. Generalized estimating equations focusing on those with moderately abnormal AEEGs showed that younger patients with seizures were significantly more likely to have moderately or markedly abnormal CEEGs than older patients without seizures. Although there was overall significant moderate agreement between the two techniques, the distribution of backgrounds assigned by AEEG was significantly different from CEEG. Most moderately abnormal AEEGs

  7. Classification Agreement Analysis of Cross-Battery Assessment in the Identification of Specific Learning Disorders in Children and Youth

    ERIC Educational Resources Information Center

    Kranzler, John H.; Floyd, Randy G.; Benson, Nicholas; Zaboski, Brian; Thibodaux, Lia

    2016-01-01

    The Cross-Battery Assessment (XBA) approach to identifying a specific learning disorder (SLD) is based on the postulate that deficits in cognitive abilities in the presence of otherwise average general intelligence are causally related to academic achievement weaknesses. To examine this postulate, we conducted a classification agreement analysis…

  8. Inter-observer agreement for diagnostic classification of esophageal motility disorders defined in high-resolution manometry.

    PubMed

    Fox, M R; Pandolfino, J E; Sweis, R; Sauter, M; Abreu Y Abreu, A T; Anggiansah, A; Bogte, A; Bredenoord, A J; Dengler, W; Elvevi, A; Fruehauf, H; Gellersen, S; Ghosh, S; Gyawali, C P; Heinrich, H; Hemmink, M; Jafari, J; Kaufman, E; Kessing, K; Kwiatek, M; Lubomyr, B; Banasiuk, M; Mion, F; Pérez-de-la-Serna, J; Remes-Troche, J M; Rohof, W; Roman, S; Ruiz-de-León, A; Tutuian, R; Uscinowicz, M; Valdovinos, M A; Vardar, R; Velosa, M; Waśko-Czopnik, D; Weijenborg, P; Wilshire, C; Wright, J; Zerbib, F; Menne, D

    2015-01-01

    High-resolution esophageal manometry (HRM) is a recent development used in the evaluation of esophageal function. Our aim was to assess the inter-observer agreement for diagnosis of esophageal motility disorders using this technology. Practitioners registered on the HRM Working Group website were invited to review and classify (i) 147 individual water swallows and (ii) 40 diagnostic studies comprising 10 swallows using a drop-down menu that followed the Chicago Classification system. Data were presented using a standardized format with pressure contours without a summary of HRM metrics. The sequence of swallows was fixed for each user but randomized between users to avoid sequence bias. Participants were blinded to other entries. (i) Individual swallows were assessed by 18 practitioners (13 institutions). Consensus agreement (≤ 2/18 dissenters) was present for most cases of normal peristalsis and achalasia but not for cases of peristaltic dysmotility. (ii) Diagnostic studies were assessed by 36 practitioners (28 institutions). Overall inter-observer agreement was 'moderate' (kappa 0.51) being 'substantial' (kappa > 0.7) for achalasia type I/II and no lower than 'fair-moderate' (kappa >0.34) for any diagnosis. Overall agreement was somewhat higher among those that had performed >400 studies (n = 9; kappa 0.55) and 'substantial' among experts involved in development of the Chicago Classification system (n = 4; kappa 0.66). This prospective, randomized, and blinded study reports an acceptable level of inter-observer agreement for HRM diagnoses across the full spectrum of esophageal motility disorders for a large group of clinicians working in a range of medical institutions. Suboptimal agreement for diagnosis of peristaltic motility disorders highlights contribution of objective HRM metrics.

  9. Faint CV Monitoring at CBA Pretoria

    NASA Astrophysics Data System (ADS)

    Monard, L. A. G. B.

    2006-05-01

    The regular monitoring of faint cataclysmic variables (CV) is one of five observing programs that are run at CBA Pretoria. It started off in 2002 with about 120 CVs and related objects in the program. The intention was to observe those targets as often as possible with unfiltered CCD. There were continuous additions of more CVs by digging deeper in the CV atlas, new finds, and reclassified stars while some were taken off the list. At the end of 2004 the number of CVs in the observing program exceeded 200. With only one telescope and one observer and so many other things to observe, the actual number of snapshot CV observations have been much less than hoped. Despite this, the program has shown to be very successful. Publications have been referring to reported findings from this program while even more publications resulted from observing campaigns (time resolved photometry) dedicated to CVs that were found in outburst by observations at CBA Pretoria. In most cases they were the first real-time outburst detection of that CV. The present paper will not deal with those published or alerted finds but will show observing results of other CVs from the list just to give an indication of the broader meaningfulness of such a program. A selection of fifteen light curves obtained after three years of monitoring will be shown and discussed. The choice of the 15 stars was based on their possible interest and the fact that they have been positively observed on most occasions, since they were mostly brighter than magnitude 18 CR (unfiltered with red zero-point).

  10. Sexual Agreement Classifications for Gay and Bisexual Men and Implications for Harm Reduction HIV Prevention

    ERIC Educational Resources Information Center

    Wilkerson, J. Michael; Smolenski, Derek J.; Morgan, Richard; Rosser, B. R. Simon

    2012-01-01

    HIV prevention educators frequently encourage gay and bisexual men (GBM) to negotiate condom use prior to sexual engagement. Identifying groups of GBM based on their presexual agreements can aid efforts to tailor interventions. Using cross-sectional data from 1,188 GBM who reported having sex with a nonprimary sex partner in the 90 days prior to…

  11. [Classification of allergens by positive percentage agreement and cluster analysis based on specific IgE antibodies in asthmatic children].

    PubMed

    Iwasaki, E; Baba, M

    1992-10-01

    Classification and characterization of allergens is important because allergic patients are sensitized by a variety of allergens. One hundred and sixty-one sera from asthmatic children were investigated for specific IgE antibodies against 35 allergens including 20 inhalants and 15 foods by means of the MAST method. We assessed the allergenic properties of the allergens based on positive percentage agreement and cluster analysis. There was a high positive percentage agreement of specific IgE antibodies between house dust and Dermatophagoides spp., a relatively high agreement between 5 molds, cat and dog epithelium, mugwort and wormwood and 5 grasses. Among the food allergens, the positive percentage agreements were relatively high, especially between cow's milk, casein, cheese, and between 3 cereal grains. In the cluster analysis, house dust and Dermatophagoides spp. made a big cluster; therefore 32 allergens except house dust and mites were analyzed. From the results of the cluster analysis, the major cluster consisted of (1) ragweed, (2) mugwort and wormwood, (3) timothy, sweet vernal, velvet and cultivated rye, (4) wheat, barley and rice, (5) molds, (6) cow's milk, casein, soybean and cheese, (7) shrimp and crab, (8) egg white, (9) Japanese cedar, (10) dog epithelium, (11) cat epithelium. The cluster of grass pollens and cereal grains made one cluster. These results tend to confirm the presence of species cross-reactivities within the major classes of allergens.

  12. Wheezes, crackles and rhonchi: simplifying description of lung sounds increases the agreement on their classification: a study of 12 physicians' classification of lung sounds from video recordings

    PubMed Central

    Melbye, Hasse; Garcia-Marcos, Luis; Brand, Paul; Everard, Mark; Priftis, Kostas; Pasterkamp, Hans

    2016-01-01

    Background The European Respiratory Society (ERS) lung sounds repository contains 20 audiovisual recordings of children and adults. The present study aimed at determining the interobserver variation in the classification of sounds into detailed and broader categories of crackles and wheezes. Methods Recordings from 10 children and 10 adults were classified into 10 predefined sounds by 12 observers, 6 paediatricians and 6 doctors for adult patients. Multirater kappa (Fleiss' κ) was calculated for each of the 10 adventitious sounds and for combined categories of sounds. Results The majority of observers agreed on the presence of at least one adventitious sound in 17 cases. Poor to fair agreement (κ<0.40) was usually found for the detailed descriptions of the adventitious sounds, whereas moderate to good agreement was reached for the combined categories of crackles (κ=0.62) and wheezes (κ=0.59). The paediatricians did not reach better agreement on the child cases than the family physicians and specialists in adult medicine. Conclusions Descriptions of auscultation findings in broader terms were more reliably shared between observers compared to more detailed descriptions. PMID:27158515

  13. Agreement between the SCORE and D’Agostino Scales for the Classification of High Cardiovascular Risk in Sedentary Spanish Patients

    PubMed Central

    Gómez-Marcos, Manuel A.; Grandes, Gonzalo; Iglesias-Valiente, José A.; Sánchez, Alvaro; Montoya, Imanol; García-Ortiz, Luis

    2009-01-01

    Background: To evaluate agreement between cardiovascular risk in sedentary patients as estimated by the new Framingham-D’Agostino scale and by the SCORE chart, and to describe the patient characteristics associated with the observed disagreement between the scales. Design: A cross-sectional study was undertaken involving a systematic sample of 2,295 sedentary individuals between 40–65 years of age seen for any reason in 56 primary care offices. An estimation was made of the Pearson correlation coefficient and kappa statistic for the classification of high risk subjects (≥20% according to the Framingham-D’Agostino scale, and ≥5% according to SCORE). Polytomous logistic regression models were fitted to identify the variables associated with the discordance between the two scales. Results: The mean risk in males (35%) was 19.5% ± 13% with D’Agostino scale, and 3.2% ± 3.3% with SCORE. Among females, they were 8.1% ± 6.8% and 1.2% ± 2.2%, respectively. The correlation between the two scales was 0.874 in males (95% CI: 0.857–0.889) and 0.818 in females (95% CI: 0.800–0.834), while the kappa index was 0.50 in males (95% CI: 0.44%–0.56%) and 0.61 in females (95% CI: 0.52%–0.71%). The most frequent disagreement, characterized by high risk according to D’Agostino scale but not according to SCORE, was much more prevalent among males and proved more probable with increasing age and increased LDL-cholesterol, triglyceride and systolic blood pressure values, as well as among those who used antihypertensive drugs and smokers. Conclusions: The quantitative correlation between the two scales is very high. Patient categorization as corresponding to high risk generates disagreements, mainly among males, where agreement between the two classifications is only moderate. PMID:20049225

  14. eP physics at the CBA

    SciTech Connect

    Wiss, J.E.; White, D.H.; Morse, W.M.

    1982-01-01

    In this report we have tried to demonstrate how a 20 x 400 GeV ep facility at the CBA will complement the physics of high energy e/sup -/e/sup +/ and hadron-hadron colliders. An ep collider will extend tests of the standard model by about an order of magnitude in spacelike momentum transfer, and extend our knowledge of electro-weak processes to a remarkable degree. It will be especially interesting to see if the lefthanded nature of the charged current observed at low spacelike momentum transfers persists to large, space momentum transfers. A high energy ep collider is unique in the opportunity to investigate QCD through the scale breaking at high Q/sup 2/ the high P/sub t/ QCD Compton process. In addition to probing small distance behavior in kinematic regions orthogonal to other collider facilities, an ep facility will generate data ultimately crucial to the understanding of the physics of e/sup +/e/sup -/ and hadron-hadron collisions. The current jet that is produced in the high energy ep neutral current process recoils against a single electron which can be used to predict the momentum of the quark which gives rise to the jet. The central problem in jet physics of deducing the kinematics of a quark by measurement of its hadronization jet can be studied under uniquely controlled circumstances. Finally the high Q/sup 2/ structure functions of the proton which are essential in understanding hard processes in hadron-hadron scattering can only be cleanly measured in an ep collider.

  15. eP physics at the CBA

    SciTech Connect

    Wiss, J.E.; White, D.H.; Morse, W.M.

    1982-01-01

    In this report we have tried to demonstrate how a 20 x 400 GeV eP facility at the CBA will complement the future physics of high energy e+e/sup -/ and hadron-hadron colliders. By offering the first glimpse of the physics of 17 TeV muon and neutrino beams, an eP collider will extend tests of the standard model by about an order of magnitude in spacelike momentum transfer, and thus close the final kinematic gap of knowledge about electro-weak processes. It will be especially interesting to test whether the lefthanded nature of the charged current observed at low spacelike momentum transfers persists to large, spacelike momentum transfers. A high energy eP collider also enables unique tests of QCD such as a study of high Q/sup 2/ scale breaking and the high P/sub t/ QCD Compton process. In addition to probing small distance behavior in kinematic regions orthogonal to other collider facilities, an eP facility will generate data useful to understanding the physics of e+e/sup -/ and hadron-hadron collisions. The current jet produced in the high energy eP neutral current process is produced against a single electron which can be used to predict the momentum of the quark which gives rise to the jet. Hence the central problem in jet physics of deducing the kinematics of a quark by measurement of its hadronization jet can be studied under uniquely controlled circumstances. Finally the high Q/sup 2/ structure functions of the proton which are essential in understanding hard process in hadron-hadron scattering can only be cleanly measured in an eP collider.

  16. Ultra-relativistic heavy ions and the CBA

    SciTech Connect

    McLerran, L.D.

    1982-01-01

    The study of ultra-relativistic heavy ions at an accelerator such as the CBA provides a unique glimpse of matter as it may have appeared in the early universe. This hot dense matter very probably appears as a quark-gluon plasma which expands and cools into hadronic matter. The CBA would provide data at the very highest energies, and produce matter at the highest energy densities. The possibility of using a cyclotron to inject very heavy ions into the AGS and then into the CBA would also allow the production of quark-gluon matter at higher energy densities than would light ions, and would make the matter in a larger volume where surface effects are minimized. At the highest energies with very heavy ions, there is great flexibility in the experimental signals which might be studied, as well as the nature of the matter which is produced. Some of the possibilities are discussed. (WHK)

  17. Gross Motor Function Classification System used in adults with cerebral palsy: agreement of self-reported versus professional rating.

    PubMed

    Jahnsen, Reidun; Aamodt, Geir; Rosenbaum, Peter

    2006-09-01

    The present study investigated the reliability of self-reported rating of Gross Motor Function Classification System (GMFCS) levels compared with professional rating, and changes in gross motor function over time, in adults with cerebral palsy. Twenty-nine females and 33 males aged between 18 years 5 months and 62 years 11 months (mean age 34y 7mo [SD 10y 6mo]) participated in the study. Participants rated their current gross motor function using the GMFCS and reported their judgement of their gross motor function at age 10 to 12 years. The project leader, a physical therapist, also classified participants' current GMFCS levels and conducted a chart review on all accessible medical records of participants' gross motor function when they were 10 to 12 years old, rating the GMFCS level accordingly. Intraclass correlation coefficients (ICC) between self-reported and professional ratings showed excellent agreement (ICC=0.93-0.95, 95% confidence interval [CI] 0.89-0.97). More than half the participants experienced a stable gross motor function from the age of 10 to 12 years to the present. Those at GMFCS Levels II and III at the age of 10 to 12 years (according to the professional rating) had significant change for the worse in gross motor function over time, with odds ratios of 9.30 (95% CI 1.2-73.0, p=0.03) and 7.00 (95% CI 1.1-43.0, p=0.04) respectively. Interview data on circumstances regarding changes in gross motor function since childhood are also reported. Changes in GMFCS level were mostly associated with physical or social environmental factors.

  18. A Study of Perceptional Typologies on Computer Based Assessment (CBA): Instructor and Student Perspectives

    ERIC Educational Resources Information Center

    Kim, Jin-Young

    2015-01-01

    This study explores and describes different viewpoints on Computer Based Assessment (CBA) by using Q methodology to identify perspectives of students and instructors and classify these into perceptional typologies. Thirty undergraduate students taking CBA courses and fifteen instructors adopting CBA into their curriculum at a university in Korea,…

  19. Cholesterol kinetic effects of dietary fat in CBA/J and C57BR/cdJ mice

    SciTech Connect

    Stewart, J.; Kuan, Soniu; Seagrave, R.; Patterson, L.; Koschorreck, R.; Dupont, J. )

    1990-02-26

    Small differences in dietary fats cause marked differences in cholesterol metabolism in different strains of mice. CBA/J mice adjust HMGCOA reductase activity and C57BR/cdJ mice change fecal excretion of cholesterol. Phenomenological compartmental modeling of movement of 4{sup 14}C-cholesterol in the two strains of mice fed 40 en % fat, P/S = 0.24 (SFA) or 30 en % fat, P/S = 1 (PUFA) was used to analyze rates of movement between serum, liver, heart, and carcass. The C57 mice had slower movement between all compartments than CBA. Residence times in tissues were longer in mice fed SFA than those fed PUFA diet. The kinetic results are in agreement with the organ concentrations and enzyme activities measured.

  20. Classification

    ERIC Educational Resources Information Center

    Clary, Renee; Wandersee, James

    2013-01-01

    In this article, Renee Clary and James Wandersee describe the beginnings of "Classification," which lies at the very heart of science and depends upon pattern recognition. Clary and Wandersee approach patterns by first telling the story of the "Linnaean classification system," introduced by Carl Linnacus (1707-1778), who is…

  1. Accountability under Constraint: The Relationship between Collective Bargaining Agreements and California Schools' and Districts' Performance under No Child Left Behind

    ERIC Educational Resources Information Center

    Strunk, Katharine O.; McEachin, Andrew

    2011-01-01

    The authors examine how the collective bargaining agreement (CBA) negotiated between teachers' unions and districts is associated with schools' and districts' performance under accountability pressures in California. They find that CBA restrictiveness is associated with the increased likelihood that districts will be in Program Improvement (PI)…

  2. Interobserver Agreement of the Gross Motor Function Classification System in an Ambulant Population of Children with Cerebral Palsy

    ERIC Educational Resources Information Center

    McDowell, Brona C.; Kerr, Claire; Parkes, Jackie

    2007-01-01

    Gross Motor Function Classification System (GMFCS) level was reported by three independent assessors in a population of children with cerebral palsy (CP) aged between 4 and 18 years (n=184; 112 males, 72 females; mean age 10y 10mo [SD 3y 7mo]). A software algorithm also provided a computed GMFCS level from a regional CP registry. Participants had…

  3. Computer Based Assessment (CBA): Perception of residents at Dow University of Health Sciences

    PubMed Central

    Jawaid, Masood; Moosa, Foad Ali; Jaleel, Farhat; Ashraf, Junaid

    2014-01-01

    Background and objective : During the past few years, Computer-based assessment (CBA) has gained popularkity as a testing modality. This assessment offers several advantages over paper based assessment (PBA) testing. The objective of this study was to find out residents’ perception of this method of assessment. Methods : The post graduate residents of Dow University of Health Sciences in the field of Surgery, Medicine, Gynecology and Obstetrics experienced their first formative Computer-based assessment (CBA) in year 2013.Immediately after formative CBA, an anonymous paper based questionnaire was distributed amongst the residents and response was sought for their self-perceived computer usage competence before starting residency, perceptions regarding CBA method and to determine their preference for PBA or CBA in future assessment preferences. Results: Total 173 residents completed the questionnaire. More than half of residents, 56.1% had no prior experience of CBA. Three fourth, 76.4% of the residents were less than confident before sitting in CBA, while after completing CBA, 64.8% were either confident or extremely confident for CBA. Most common problem encountered by students was logging in 28.9%. More students (53.2%) believed that paper assessment took longer to complete than CBA. Majority of the students (61.8%) rated CBA as better than PBA despite experiencing it for the first time. Conclusion: Resident’s perception for CBA is good and they recommend its use in future assessment as well. However, to take maximal advantage of this technology, faculty should be trained to develop questions not only with text and pictures but with audio and video support. PMID:25097497

  4. Using of CBA Method for Evaluation of the Investments in the Link with Social Responsible Business

    NASA Astrophysics Data System (ADS)

    Mrvová, Ľubica; Vaňová, Jaromíra

    2012-12-01

    The paper presents knowledge from the area of economic efficiency assessment of the environmental investments, in the link with environmental management with context of social responsible business and their mutual connection, on the base of CBA method. CBA method creates basis for the software CBA1.1, which was created for the needs of business practise for the small and medium enterprises in the Slovak Republic.

  5. Classification.

    PubMed

    Tuxhorn, Ingrid; Kotagal, Prakash

    2008-07-01

    In this article, we review the practical approach and diagnostic relevance of current seizure and epilepsy classification concepts and principles as a basic framework for good management of patients with epileptic seizures and epilepsy. Inaccurate generalizations about terminology, diagnosis, and treatment may be the single most important factor, next to an inadequately obtained history, that determines the misdiagnosis and mismanagement of patients with epilepsy. A stepwise signs and symptoms approach for diagnosis, evaluation, and management along the guidelines of the International League Against Epilepsy and definitions of epileptic seizures and epilepsy syndromes offers a state-of-the-art clinical approach to managing patients with epilepsy.

  6. Classification

    NASA Technical Reports Server (NTRS)

    Oza, Nikunj C.

    2011-01-01

    A supervised learning task involves constructing a mapping from input data (normally described by several features) to the appropriate outputs. Within supervised learning, one type of task is a classification learning task, in which each output is one or more classes to which the input belongs. In supervised learning, a set of training examples---examples with known output values---is used by a learning algorithm to generate a model. This model is intended to approximate the mapping between the inputs and outputs. This model can be used to generate predicted outputs for inputs that have not been seen before. For example, we may have data consisting of observations of sunspots. In a classification learning task, our goal may be to learn to classify sunspots into one of several types. Each example may correspond to one candidate sunspot with various measurements or just an image. A learning algorithm would use the supplied examples to generate a model that approximates the mapping between each supplied set of measurements and the type of sunspot. This model can then be used to classify previously unseen sunspots based on the candidate's measurements. This chapter discusses methods to perform machine learning, with examples involving astronomy.

  7. Analysis of CMM - Based Appraisal for Internal Process Improvement (CBA IPI) Assessment Feedback

    DTIC Science & Technology

    2001-11-01

    assessment team mem- bers, and Lead Assessors who are interested in learning about other assessors ’ experiences in order to improve their own...Internal Process Improvement (CBA IPI) Assessment Feedback Donna K. Dunaway, PhD Michele Baker November 2001 Pittsburgh, PA 15213...3890 Analysis of CMM®-Based Appraisal for Internal Process Improvement (CBA IPI) Assessment Feedback CMU/SEI-2001-TR-021 ESC-TR

  8. Non-epithelial uterine tumours induced in CBA mice by 1,2-dimethylhydrazine.

    PubMed

    Turusov, V S; Bazlova, L S; Lanko, N S

    1977-07-01

    In CBA mice treated with weekly subcutaneous injections of 1,2-dimethylhydrazine an unusually high incidence of uterine sarcomas was observed in two successive experiments. The tumours are easily transplantable. The description of their histological structure is presented and their histogenesis is discussed.

  9. Marinobacter adhaerens HP15 harbors two CzcCBA efflux pumps involved in zinc detoxification.

    PubMed

    Stahl, Antje; Pletzer, Daniel; Mehmood, Amna; Ullrich, Matthias S

    2015-09-01

    Several members of the ubiquitously found γ-proteobacterial genus Marinobacter were described or assumed to inhabit marine environments naturally enriched in heavy metals. However, direct studies that describe the ability of this genus to occupy such environments have not been conducted. To cope with heavy metal stress, bacteria possess specific efflux pumps as tools for detoxification, among which the CzcCBA type efflux system is one representative. Previous studies showed that this system plays an important role in resistance towards cadmium, zinc, and cobalt. Up to now, no study had focused on characterization of Czc pumps in Marinobacter sp. or other marine prokaryotes. Herein, we elucidated the function of two CzcCBA pumps encoded by Marinobacter adhaerens HP15's genome during exposure to cadmium, zinc, and cobalt. Single and double knock-out mutants lacking the corresponding two czcCBA operons were generated and analyzed in terms of their resistance profiles. Both operons appeared to be important for zinc resistance but had no role in tolerance towards cadmium or cobalt. One of the mutations was genetically complemented thereby restoring the wild type phenotype. In accordance with the resistance pattern, expression of the genes coding for both CzcCBA pumps was induced by zinc but neither by cadmium nor cobalt.

  10. Evaluation of Lassa virus vaccine immunogenicity in a CBA/J-ML29 mouse model.

    PubMed

    Goicochea, Marco A; Zapata, Juan C; Bryant, Joseph; Davis, Harry; Salvato, Maria S; Lukashevich, Igor S

    2012-02-14

    Lassa fever (LF) is one of the most prevalent viral hemorrhagic fevers in West Africa responsible for thousands of deaths annually. The BSL-4 containment requirement and lack of small animal model to evaluate Lassa virus (LASV)-specific cell-mediated immunity (CMI) complicate development of effective LF vaccines. Here we have described a CBA/J-ML29 model allowing evaluation of LASV-specific CMI responses in mice. This model is based on Mopeia virus reassortant clone ML29, an attractive immunogenic surrogate for LASV. A single intraperitoneal (i.p.) immunization of CBA/J mice with ML29 protected animals against a lethal homologous intracerebral (i.c.) challenge with 588 LD(50). The ML29-immunized mice displayed negligible levels of LASV-specific antibody titers, but LASV-specific CMI responses were detectable early and peaked on day 8-10 after immunization. A T cell cytotoxicity assay in vivo showed a correlation between LASV-specific cytotoxicity and the timing of protection induced by the ML29 immunization. Notably, CBA/J mice that received CD8+ T cell-depleted splenocytes from ML29-immunized donors all succumbed to a lethal i.c. challenge, demonstrating that CD8+ T cells are critical in protection. The CBA/J-ML29 model can be useful immunological tool for the preliminary evaluation of immunogenicity and efficacy of vaccine candidates against LASV outside of BSL-4 containment facilities.

  11. Ranking of Sudden Ionospheric Disturbances by Means of the Duration of Vlf Perturbed Signal in Agreement with Satellite X-Ray Flux Classification

    NASA Astrophysics Data System (ADS)

    Ammar, Ahmed; Ghalila, Hassen

    2016-12-01

    Ionosphere undergoes permanently solar flares that quickly change its properties inducing sometime unwanted effects. These changes, or events, are known as Sudden Ionospheric Disturbances (SIDs) and the knowledge of their magnitude may be of great interest to anticipate probable damages. Currently, there does not exist any classification of these ionospheric changes based on their amplitude due to the wide variability of its responses. The only way to surmise their importance is to study them indirectly, throughout the classification of the X-ray flux intensity recorded by satellites. An attempt of classification based on their duration was proposed by the American Association of Variable Star Observers (AAVSO) but it is not very accurate because SID's duration is measured directly from the raw signal of the Very Low Frequency (VLF) signal and/or the Low Frequency (LF) signal. The aim of this work is to investigate, through a set of simple mathematical techniques applied to VLF/LF signals recorded by ground based receivers, the best method to estimate SIDs durations and then propose a new classification based on these durations.

  12. Inconvenient Truth? Do Collective Bargaining Agreements Help Explain the Mobility of Teachers within School Districts?

    ERIC Educational Resources Information Center

    Goldhaber, Dan; Lavery, Lesley; Theobald, Roddy

    2016-01-01

    We utilize detailed teacher-level longitudinal data from Washington State to investigate patterns of teacher mobility in districts with different collective bargaining agreement (CBA) transfer provisions. Specifically, we estimate the log odds that teachers of varying experience and effectiveness levels transfer out of their schools to other…

  13. Draft genome sequence of the Chilean isolate Aeromonas salmonicida strain CBA100.

    PubMed

    Valdes, Natalia; Espinoza, Carolina; Sanhueza, Loreto; Gonzalez, Alex; Corsini, Gino; Tello, Mario

    2015-03-01

    We report the draft genome sequence from Aeromonas salmonicida sp. strain CBA100, which was characterized as an antibiotic-resistant bacterium isolated from infected rainbow trout. The total size of the genome is 4,788,109 bp, with a G + C content of 60.55%. Comparison of its open reading frames shows that the closest homologue to one third of the genes of strain CBA100 are found in A. hydrophila. The strain contains several efflux pumps and putative genes that confer resistance to multiclass antibiotics, including macrolide, β-lactamics, florfenicol and quinolones. The antibiogram profile suggests that efflux pumps are the main mechanism of resistance to non-β-lactamic antibiotics. This is the first genome of a Chilean isolate of A. salmonicida, which should shed light on the design of strain-specific vaccines against this pathogen and reduce the use of antibiotics for preventive treatment in Chilean aquaculture.

  14. Arthritis of mice induced by Mycoplasma arthritidis. Humoral antibody and lymphocyte responses of CBA mice.

    PubMed Central

    Cole, B C; Golightly-Rowland, L; Ward, J R

    1976-01-01

    Peak arthritis occurred 7 days after intravenous injection of CBA mice with Mycoplasma arthritidis and persisted in some animals for 84 days. A marked leucocytosis was apparent for the first 21 days. Complement-fixing antibodies reached a peak 14 days after injection of the organisms and persisted at high levels for 84 days. Metabolic-inhibiting and mycoplasmacidal antibodies were present but at much lower titres. PMID:1275576

  15. Bridging the gap between LCA, LCC and CBA as sustainability assessment tools

    SciTech Connect

    Hoogmartens, Rob; Van Passel, Steven; Van Acker, Karel; Dubois, Maarten

    2014-09-15

    Increasing interest in sustainability has led to the development of sustainability assessment tools such as Life Cycle Analysis (LCA), Life Cycle Costing (LCC) and Cost–Benefit Analysis (CBA). Due to methodological disparity of these three tools, conflicting assessment results generate confusion for many policy and business decisions. In order to interpret and integrate assessment results, the paper provides a framework that clarifies the connections and coherence between the included assessment methodologies. Building on this framework, the paper further focuses on key aspects to adapt any of the methodologies to full sustainability assessments. Aspects dealt with in the review are for example the reported metrics, the scope, data requirements, discounting, product- or project-related and approaches with respect to scarcity and labor requirements. In addition to these key aspects, the review shows that important connections exist: (i) the three tools can cope with social inequality, (ii) processes such as valuation techniques for LCC and CBA are common, (iii) Environmental Impact Assessment (EIA) is used as input in both LCA and CBA and (iv) LCA can be used in parallel with LCC. Furthermore, the most integrated sustainability approach combines elements of LCA and LCC to achieve the Life Cycle Sustainability Assessment (LCSA). The key aspects and the connections referred to in the review are illustrated with a case study on the treatment of end-of-life automotive glass. - Highlights: • Proliferation of assessment tools creates ambiguity and confusion. • The developed assessment framework clarifies connections between assessment tools. • Broadening LCA, key aspects are metric and data requirements. • Broadening LCC, key aspects are scope, time frame and discounting. • Broadening CBA, focus point, timespan, references, labor and scarcity are key.

  16. Analysis of Lead Assessor Feedback for CBA IPI Assessments Conducted July 1998 - October 1999

    DTIC Science & Technology

    2000-04-01

    feedback data are required of a Lead Assessor in order to monitor the consistency of use of the assessment method for quality control purposes. Data...In the Appraiser Program of the Software Engineering Institute (SEI), authorized Lead Assessors lead Capability Maturity Model-Based Appraisals for...Internal Process Improvement (CBA IPI). At the conclusion of each assessment, they are required to submit certain artifacts to the SEI. Data from

  17. Lactobacillus paracasei CBA L74 interferes with gliadin peptides entrance in Caco-2 cells.

    PubMed

    Sarno, Marco; Lania, Giuliana; Cuomo, Marialaura; Nigro, Federica; Passannanti, Francesca; Budelli, Andrea; Fasano, Francesca; Troncone, Riccardo; Auricchio, Salvatore; Barone, Maria Vittoria; Nigro, Roberto; Nanayakkara, Merlin

    2014-12-01

    Several recent reports describe a role of probiotics as a therapeutic approach for celiac disease (CD). Two undigested A-gliadin peptides, P31-43 and P57-68, are central to CD pathogenesis, inducing an innate and an adaptive immune response, respectively. They enter enterocytes and localize to vesicular compartment to induce their toxic/immunogenics effects. In this article, we tested the effect of probiotic Lactobacillus paracasei (LP) CBA L74 (International Depository Accession Number LMG P-24778), its supernatant and LP-fermented cereals on gliadin peptides, P31-43 and P57-68, entrance in Caco-2 cells. Both LP CBA L74 and its supernatant inhibit P31-43 (intensity of fluorescence; FI: 75%) and P57-68 (FI: 50%) entrance in Caco2 cells, indicating that this biological effect is due to some product included in LP CBA L74 supernatant. This effect was present also after fermentation of cereals. This study describes a novel effect of probiotics in the prevention of undigested gliadin peptides toxic effects.

  18. Chromosomal abnormalities in neutron-induced acute myeloid leukemias in CBA/H mice

    SciTech Connect

    Bouffler, S.D.; Meijne, E.I.M.; Huiskamp, R.

    1996-09-01

    Acute myeloid leukemias (AMLs) induced in CBA/H mice by 1 MeV fission neutrons have been examined for chromosomal abnormalities by G-band analysis. In common with X-ray- and {alpha}-particle-induced AMLs in CBA/H mice, more than 90% (16/17) of the myeloid leukemias had chromosome 2 abnormalities, in this case, all interstitial deletions. Chromosome 2 breakpoints were not wholly consistent, but clustering in three specific G-band regions was observed. Very distal (H-region) breakpoints were more common in the neutron AMLs than in X-ray- or {alpha}-particle-induced leukemias. These data indicate that neutron-induced AMLs in CBA/H mice are not characterized by a specific chromosome deletion but that a variety of chromosome 2 deletion types are associated with the disease. Trisomy of chromosome 1 (12.5% AMLs) and aneusomy of chromosomes 6 (31% AMLs) and Y (37.5% AMLs) were noted. While chromatid breakage was observed occasionally in neutron-induced AML, no clear indications of persistent chromosomal instability or high levels of stable chromosomal change were apparent. 19 refs., 1 fig., 1 tab.

  19. Draft genome sequence of Halapricum salinum CBA1105(T), an extremely halophilic archaeon isolated from solar salt.

    PubMed

    Song, Hye Seon; Lee, Hae-Won; Yim, Kyung June; Nam, Young-Do; Choi, Jong-Soon; Choi, Hak-Jong; Seo, Myung-Ji; Kim, Kil-Nam; Kim, Daekyung; Rhee, Jin-Kyu; Roh, Seong Woon

    2014-12-01

    Halapricum salinum CBA1105(T) (=KCTC 4202(T), JCM 19729(T)) is an extremely halophilic archaeon isolated from solar salt in the Republic of Korea. We present the draft genome of CBA1105(T), which is assembled into 3 contigs containing 3,451,492bp with a G+C content of 63.7%. This is the first genome that has been sequenced in the genus Halapricum.

  20. [Tumors in CBA line mice caused by 1,2-dimethylhydrazine].

    PubMed

    Turusov, V S; Lanko, N S; Bazlova, L S

    1977-01-01

    Female CBA mice were treated weekly with subcutaneous injections of 1,2-dimethyl-hydrazine (8 mg/Kg b. w.) for 38--40 weeks. All animals but one developed tumors, mainly of the uterus, and region and intestine. Uterine tumors were most likely endometrial sarcomas, although myometrial and vascular components were also present. Large tumors of the anal region were squamous cell or baso-squamous carcinomata, while small growths were sebaceous adenomas or basal-cell tumors. 1.2-dimethylhydrazine appears to be a more multipotent carcinogen for mice than for the rat. Uterine sarcomas are of special interest in view of their rarity in mice.

  1. District Self-Assessment Tool: For Modification of Collective Bargaining Agreements to Achieve Flexible Conditions for School Turnaround

    ERIC Educational Resources Information Center

    Mass Insight Education (NJ1), 2011

    2011-01-01

    The District Self-Assessment Tool is designed to support districts, unions and Lead Partners, when analyzing their existing collective bargaining agreement (CBA) with the intention of making targeted modifications to support the implementation of dramatic reform in the district's lowest-performing schools. By outlining objectives and suggested…

  2. A polymorphic and hypervariable locus in the pseudoautosomal region of the CBA/H mouse sex chromosomes

    SciTech Connect

    Fennelly, J.; Laval, S.; Wright, E.; Plumb, M.

    1996-04-01

    We have identified a genomic locus (DXYH1) that is polymorphic and hypervariable within the CBA/H colony. Using a panel of C57BL/6 x Mus spretus backcross offspring, it was mapped to the distal end of the X chromosome. Pseudoautosomal inheritance was demonstrated through three generations of CBA/H x CBA/H and CBA/H x C57BL/6 crosses and confirmed through linkage to the Sxr locus in X/Y Sxr x 3H1 crosses. Meiotic recombination frequencies place DXYH1 {approximately}28% into the pseudoautosomal region from the boundary. The de novo generation of CBA/H variant DXYH1 restriction fragment length polymorphisms during spermatogenesis is suggestive of the germline instability associated with hypermutable human minisatellites. The absence of DXY1-related sequences in Mus spretus provides DNA sequence evidence to support the observed failure of X-Y pairing during meiosis and consequent hybrid infertility in C57BL/6 x Mus spretus male F1 offspring. 19 refs., 4 figs.

  3. Long-Term Dietary Folate Deficiency Accelerates Progressive Hearing Loss on CBA/Ca Mice

    PubMed Central

    Martínez-Vega, Raquel; Murillo-Cuesta, Silvia; Partearroyo, Teresa; Varela-Moreiras, Gregorio; Varela-Nieto, Isabel; Pajares, María A.

    2016-01-01

    Dietary folic acid deficiency induced early hearing loss in C57BL/6J mice after 2-months, corroborates the epidemiological association previously described between vitamin deficiency and this sensory impairment. However, this strain is prone to early hearing loss, and hence we decided to analyze whether the effects exerted by folate deprivation follow the same pattern in a mouse strain such as CBA/Ca, which is resistant to hearing impairment. Here, we show results of a long-term study on hearing carried out on CBA/Ca mice subjected to dietary folate deprivation. Systemic changes included decreased serum folate levels, hyperhomocysteinemia and signs of anemia in the group fed with folate-deficient (FD) diet. Initial signs of hearing loss were detected in this strain after 8-months of vitamin deficiency, and correlated with histological damage in the cochleae. In conclusion, the data presented reinforce the importance of adequate folic acid levels for the auditory system and suggest that the impact of dietary deficiencies may depend on the genetic background. PMID:27630560

  4. Using the mouse grimace scale and behaviour to assess pain in CBA mice following vasectomy.

    PubMed

    Miller, Amy L; Kitson, Gemma L; Skalkoyannis, Benjamin; Flecknell, Paul A; Leach, Matthew C

    2016-08-01

    Mice used in biomedical research should have pain reduced to an absolute minimum through refinement of procedures or by the provision of appropriate analgesia. Vasectomy is a common and potentially painful surgical procedure carried out on male mice to facilitate the production of genetically modified mice. The aim of our study was to determine if 0.05 mg/kg buprenorphine would ameliorate pain associated changes following abdominal vasectomy and to determine if the mouse grimace scale is an appropriate tool for the assessment of pain in this model. Eight male CBA mice underwent abdominal vasectomy as part of a genetically modified mouse-breeding programme. Here we assessed pain using a previously validated behaviour-based method and the mouse grimace scale. All mice received buprenorphine (0.05 mg/kg s.c.) pre-surgery. Behaviour and grimace scores were compared between baseline (pre-surgery), 30 min, 5 h, 24 h and 25 h post surgery. Following 24 h post-op, all mice were administered 5 mg/kg meloxicam (s.c.) as additional analgesia. Significant increases in specific pain behaviours and mouse grimace scale score were found 30 min post surgery. At 5 h post surgery, scores were returning to baseline levels. Frequency of rearing was significantly decreased at both 30 min and 5 h post surgery compared to baseline, demonstrating a longer lasting change in normal exploratory behaviour. Buprenorphine (0.05 mg/kg) was ineffective at ameliorating these pain-associated changes in CBA mice and should be considered inadequate at this dose. By 24 h post surgery, pain associated behaviours, grimace scale and rearing had all returned to baseline levels. There was no change in pain behaviours or MGS following administration of meloxicam indicating that an additional dose of meloxicam does not appear to offer benefit at this point. Using the mouse grimace scale to assess pain in mice, appeared to be effective in the immediate post vasectomy period in CBA mice

  5. FRETS-VWF73 rather than CBA assay reflects ADAMTS13 proteolytic activity in acquired thrombotic thrombocytopenic purpura patients.

    PubMed

    Mancini, I; Valsecchi, C; Lotta, L A; Deforche, L; Pontiggia, S; Bajetta, M; Palla, R; Vanhoorelbeke, K; Peyvandi, F

    2014-08-01

    Collagen-binding activity (CBA) and FRETS-VWF73 assays are widely adopted methods for the measurement of the plasmatic activity of ADAMTS13, the von Willebrand factor (VWF) cleaving-protease. Accurately assessing the severe deficiency of ADAMTS13 is important in the management of thrombotic thrombocytopenic purpura (TTP). However, non-concordant results between the two assays have been reported in a small but relevant percentage of TTP cases. We investigated whether CBA or FRETS-VWF73 assay reflects ADAMTS13 proteolytic activity in acquired TTP patients with non-concordant measurements. Twenty plasma samples with non-concordant ADAMTS13 activity results, <10% using FRETS-VWF73 and ≥20% using CBA, and 11 samples with concordant results, <10% using either FRETS-VWF73 and CBA assays, were analysed. FRETS-VWF73 was performed in the presence of 1.5 M urea. ADAMTS13 activities were also measured under flow conditions and the VWF multimer pattern was defined in order to verify the presence of ultra-large VWF due to ADAMTS13 deficiency. In FRETS-VWF73 assay with 1.5 M urea, ADAMTS13 activity significantly increased in roughly 50% of the samples with non-concordant results, whereas it remained undetectable in all samples with concordant measurements. Under flow conditions, all tested samples showed reduced ADAMTS13 activity. Finally, samples with non-concordant results showed a ratio of high molecular weight VWF multimers higher than normal. Our results support the use of FRETS-VWF73 over CBA assay for the assessment of ADAMTS13 severe deficiency and indicate urea as one cause of the observed differences.

  6. Genomic Analysis of the Extremely Halophilic Archaeon Halobacterium noricense CBA1132 Isolated from Solar Salt That Is an Essential Material for Fermented Foods.

    PubMed

    Lim, Seul Ki; Kim, Joon Yong; Song, Hye Seon; Kwon, Min-Sung; Lee, Jieun; Oh, Young Jun; Nam, Young-Do; Seo, Myung-Ji; Lee, Dong-Gi; Choi, Jong-Soon; Yoon, Changmann; Sohn, Eunju; Rahman, Md Arif-Ur; Roh, Seong Woon; Choi, Hak-Jong

    2016-08-28

    The extremely halophilic archaeon Halobacterium noricense is a member of the genus Halobacterium. Strain CBA1132 (= KCCM 43183, JCM 31150) was isolated from solar salt. The genome of strain CBA1132 assembled with 4 contigs, including three rRNA genes, 44 tRNA genes, and 3,208 open reading frames. Strain CBA1132 had nine putative CRISPRs and the genome contained genes encoding metal resistance determinants: copper-translocating P-type ATPase (CtpA), arsenical pump-driving ATPase (ArsA), arsenate reductase (ArsC), and arsenical resistance operon repressor (ArsR). Strain CBA1132 was related to Halobacterium noricense, with 99.2% 16S rRNA gene sequence similarity. Based on the comparative genomic analysis, strain CBA1132 has distinctly evolved; moreover, essential genes related to nitrogen metabolism were only detected in the genome of strain CBA1132 among the reported genomes in the genus Halobacterium. This genome sequence of Halobacterium noricense CBA1132 may be of use in future molecular biological studies.

  7. Inconvenient Truth? Do Collective Bargaining Agreements Help Explain the Mobility of Teachers within School Districts? CEDR Working Paper. WP #2015-­1

    ERIC Educational Resources Information Center

    Goldhaber, Dan; Lavery, Lesley; Theobald, Roddy

    2015-01-01

    We investigate patterns of teacher mobility in districts with different collective bargaining agreement (CBA) transfer provisions. We use detailed teacher-level longitudinal data from Washington State to estimate the probability that teachers of varying experience and effectiveness levels transfer out of their schools to another school in the…

  8. Embryonic/fetal mortality and intrauterine growth restriction is not exclusive to the CBA/J sub-strain in the CBA × DBA model

    PubMed Central

    McKelvey, Kelly J.; Yenson, Vanessa M.; Ashton, Anthony W.; Morris, Jonathan M.; McCracken, Sharon A.

    2016-01-01

    Inbred strains of mice are powerful models for understanding human pregnancy complications. For example, the exclusive mating of CBA/J females to DBA/2J males increases fetal resorption to 20–35% with an associated decline in placentation and maintenance of maternal Th1 immunity. More recently other complications of pregnancy, IUGR and preeclampsia, have been reported in this model. The aim of this study was to qualify whether the CBA/CaH substrain female can substitute for CBA/J to evoke a phenotype of embryonic/fetal mortality and IUGR. (CBA/CaH × DBA/2J) F1 had significantly higher embryonic/fetal mortality mortality (p = 0.0063), smaller fetuses (p < 0.0001), and greater prevalence of IUGR (<10th percentile; 47% vs 10%) than (CBA/CaH × Balb/c) F1. Placentae from IUGR fetuses from all mating groups were significantly smaller (p < 0.0001) with evidence of thrombosis and fibrosis when compared to normal-weight fetuses ( > 10th percentile). In addition, placentae of “normal-weight” (CBA/CaH × DBA/2J) F1 were significantly smaller (p < 0.0006) with a greater proportion of labyrinth (p = 0.0128) and an 11-fold increase in F4/80 + macrophage infiltration (p < 0.0001) when compared to placentae of (CBA/CaH × Balb/c) F1. In conclusion, the embryonic/fetal mortality and IUGR phenotype is not exclusive to CBA/J female mouse, and CBA/CaH females can be substituted to provide a model for the assessment of novel therapeutics. PMID:27767070

  9. Active suppression of host-vs-graft reaction in pregnant mice. VII. Spontaneous abortion of allogeneic CBA/J x DBA/2 fetuses in the uterus of CBA/J mice correlates with deficient non-T suppressor cell activity

    SciTech Connect

    Clark, D.A.; Chaput, A.; Tutton, D.

    1986-03-01

    The mammalian fetus has been viewed as an unusually successful type of allograft and unexplained spontaneous abortion as a possible example of maternal rejection. Previous studies have shown the presence of small lymphocytic suppressor cells in the murine decidua which block the generation and reactivation of anti-paternal cytotoxic T lymphocytes (CTL) and lymphokine-activated killer cells (LAK) by elaborating a factor that inhibits the response to interleukin 2 (IL 2). A deficiency of these suppressor cells was associated with implants of xenogeneic Mus caroli embryos in the Mus musculus uterus which are infiltrated by maternal lymphoid cells and aborted. A deficiency of such suppressor cells in the lymph nodes draining the uterus of CBA/J females in the process of aborting their semi-allogeneic CBA x DBA/2 F/sub 1/ progeny has also been shown. CBA/J females possess significantly lower levels of decidua-associated non-T suppressor cells on day 8.5 to 10.5 of allopregnancy than do mothers that will produce large litters of live babies. The F/sub 1/ embryos are infiltrated by maternal lymphocytes prior to abortion, and the infiltration and abortion rate appears to be augmented by pre-immunization with paternal DBA/2 spleen cells. The CBA/J x DBA/2J mating combination provides a model of spontaneous abortion in which immunologic factors play an important role and demonstrates that the association between deficiency of decidua-associated suppressor cells and xenopregnancy failure also holds true for the failure of allopregnancies resulting from natural within-species mating.

  10. Physical and Chemical Properties of Coal Bottom Ash (CBA) from Tanjung Bin Power Plant

    NASA Astrophysics Data System (ADS)

    Izzati Raihan Ramzi, Nurul; Shahidan, Shahiron; Zulkhairi Maarof, Mohamad; Ali, Noorwirdawati

    2016-11-01

    The objective of this study is to determine the physical and chemical characteristics of Coal Bottom Ash (CBA) obtained from Tanjung Bin Power Plant Station and compare them with the characteristics of natural river sand (as a replacement of fine aggregates). Bottom ash is the by-product of coal combustion during the electricity generating process. However, excess bottom ash production due to the high production of electricity in Malaysia has caused several environmental problems. Therefore, several tests have been conducted in order to determine the physical and chemical properties of bottom ash such as specific gravity, density, particle size distribution, Scanning Electron Microscopic (SEM) and X- Ray Fluorescence (XRF) in the attempt to produce sustainable material from waste. The results indicated that the natural fine aggregate and coal bottom ash have very different physical and chemical properties. Bottom ash was classified as Class C ash. The porous structure, angular and rough texture of bottom ash affected its specific gravity and particle density. From the tests, it was found that bottom ash is recommended to be used in concrete as a replacement for fine aggregates.

  11. [Alteration of Social Behaviors in Male Mice of CBA/Lac Strain under Agonistic Interactions].

    PubMed

    Kovalenko, I L; Kudryavtseva, N N

    2015-01-01

    Ability of people to communicate with each other is a necessary component of social behavior and normal development of individuals living in community. A pronounced impairment in communication may be the result of autism which is characterized by impaired socialization, low communication and restricted and/or repetitive behaviors. It is hypothesized that genes or rare mutations play a key role in the development of autism. However a multifold increase of the cases with autistic spectrum symptoms over the last years cannot be attributed exclusively to genetic mutations or heredity. Environmental contribution to the development of autistic symptoms has to be considered. The paper aimed to analyze the social behaviors of CBA/Lac mice with repeated experience of aggression or social defeats in daily agonistic interactions with accent on searches of associations with autistic symptoms in comparison with previously studied C57BL/6J animals. It has been shown that male mice of both strains with alternative social behaviors demonstrated the changes in social behaviors; however the expression of some form of behaviors was different. The data obtained to assert that long-term hostile social environment lead to development of disturbances in social behaviors, accompanying by autistic-like symptoms.

  12. Structures of homologous composite transposons carrying cbaABC genes from Europe and North America.

    PubMed

    Di Gioia, D; Peel, M; Fava, F; Wyndham, R C

    1998-05-01

    IS1071 is a class II transposable element carrying a tnpA gene related to the transposase genes of the Tn3 family. Copies of IS1071 that are conserved with more than 99% nucleotide sequence identity have been found as direct repeats flanking a remarkable variety of catabolic gene sequences worldwide. The sequences of chlorobenzoate catabolic transposons found on pBRC60 (Tn5271) in Niagara Falls, N.Y., and on pCPE3 in Bologna, Italy, show that these transposons were formed from highly homologous IS1071 and cbaABC components (levels of identity, > 99.5 and > 99.3%, respectively). Nevertheless, the junction sequences between the IS1071L and IS1071R elements and the internal DNA differ by 41 and 927 bp, respectively, suggesting that these transposons were assembled independently on the two plasmids. The formation of the right junction in both transposons truncated an open reading frame for a putative aryl-coenzyme A ligase with sequence similarity to benzoate- and p-hydroxybenzoate-coenzyme A ligases of Rhodopseudomonas palustris.

  13. Relative biological effectiveness of tritium for induction of myeloid leukemia in CBA/H mice.

    PubMed

    Johnson, J R; Myers, D K; Jackson, J S; Dunford, D W; Gragtmans, N J; Wyatt, H M; Jones, A R; Percy, D H

    1995-10-01

    To help resolve uncertainties as to the most appropriate weighting factor for tritium beta rays, a large experiment was carried out to measure the relative biological effectiveness (RBE) of tritiated water compared to X rays for the induction of myeloid leukemia in male mice of the CBA/H strain. The study was designed to estimate the lifetime incidence of myeloid leukemia in seven groups of about 750 mice each; radiation exposures were approximately 0, 1, 2 and 3 Gy both for tritiated water and for X rays. The lifetime incidence of leukemia in these mice increased from 0.13% in the control group to 6-8% in groups exposed to higher radiation doses. The results were fitted to various equations relating leukemia incidence to radiation dose, using both the raw data and data corrected for cumulative mouse-days at risk. The calculated RBE values for tritium beta rays compared to X rays ranged from 1.0 +/- 0.5 to 1.3 +/- 0.3. A best estimate of the RBE for this experiment was about 1.2 +/- 0.3. A wR value of 1 would thus appear to be more appropriate than a wR of 2 for tritium beta rays.

  14. 14 CFR § 1274.935 - Security classification requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... COOPERATIVE AGREEMENTS WITH COMMERCIAL FIRMS Other Provisions and Special Conditions § 1274.935 Security classification requirements. Security Classification Requirements July 2002 Performance under this...

  15. Metabolic Pathway Involved in 6-Chloro-2-Benzoxazolinone Degradation by Pigmentiphaga sp. Strain DL-8 and Identification of the Novel Metal-Dependent Hydrolase CbaA

    PubMed Central

    Dong, Weiliang; Wang, Fei; Huang, Fei; Wang, Yicheng; Zhou, Jie; Ye, Xianfeng; Li, Zhoukun; Hou, Ying; Huang, Yan; Ma, Jiangfeng; Jiang, Min

    2016-01-01

    ABSTRACT 6-Chloro-2-benzoxazolinone (CDHB) is a precursor of herbicide, insecticide, and fungicide synthesis and has a broad spectrum of biological activity. Pigmentiphaga sp. strain DL-8 can transform CDHB into 2-amino-5-chlorophenol (2A5CP), which it then utilizes as a carbon source for growth. The CDHB hydrolase (CbaA) was purified from strain DL-8, which can also hydrolyze 2-benzoxazolinone (BOA), 5-chloro-2-BOA, and benzamide. The specific activity of purified CbaA was 5,900 U · mg protein−1 for CDHB, with Km and kcat values of 0.29 mM and 8,500 s−1, respectively. The optimal pH for purified CbaA was 9.0, the highest activity was observed at 55°C, and the inactive metal-free enzyme could be reactivated by Mg2+, Ni2+, Ca2+, or Zn2+. Based on the results obtained for the CbaA peptide mass fingerprinting and draft genome sequence of strain DL-8, cbaA (encoding 339 amino acids) was cloned and expressed in Escherichia coli BL21(DE3). CbaA shared 18 to 21% identity with some metal-dependent hydrolases of the PF01499 family and contained the signature metal-binding motif Q127XXXQ131XD133XXXH137. The conserved amino acid residues His288 and Glu301 served as the proton donor and acceptor. E. coli BL21(DE3-pET-cbaA) resting cells could transform 0.2 mM CDHB into 2A5CP. The mutant strain DL-8ΔcbaA lost the ability to degrade CDHB but retained the ability to degrade 2A5CP, consistent with strain DL-8. These results indicated that cbaA was the key gene responsible for CDHB degradation by strain DL-8. IMPORTANCE 2-Benzoxazolinone (BOA) derivatives are widely used as synthetic intermediates and are also an important group of allelochemicals acting in response to tissue damage or pathogen attack in gramineous plants. However, the degradation mechanism of BOA derivatives by microorganisms is not clear. In the present study, we reported the identification of CbaA and metabolic pathway responsible for the degradation of CDHB in Pigmentiphaga sp. DL-8. This will provide

  16. 37 CFR 2.85 - Classification schedules.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... international classification pursuant to § 2.85(e)(3). (b) Prior United States classification system. Section 6... pursuant to § 2.85(e)(3); or (2) The registration was issued under a classification system prior to that... application. (e) Changes to Nice Agreement. The international classification system changes...

  17. Different Cellular and Genetic Basis of Noise-Related Endocochlear Potential Reduction in CBA/J and BALB/cJ Mice

    PubMed Central

    Rosen, Allyson D.; Rellinger, Erin A.; Montgomery, Scott C.; Gagnon, Patricia M.

    2010-01-01

    The acute and permanent effects of noise exposure on the endocochlear potential (EP) and cochlear lateral wall were evaluated in BALB/cJ (BALB) inbred mice, and compared with CBA/J (CBA) and C57BL/6 (B6) mice. Two-hour exposure to broadband noise (4–45 kHz) at 110 dB SPL leads to a ~50 mV reduction in the EP in BALB and CBA, but not B6. EP reduction in BALB and CBA is reliably associated with characteristic acute cellular pathology in stria vascularis and spiral ligament. By 8 weeks after exposure, the EP in CBA mice has returned to normal. In BALBs, however, the EP remains depressed by an average ~10 mV, so that permanent EP reduction contributes to permanent threshold shifts in these mice. We recently showed that the CBA noise phenotype in part reflects the influence of a large effect quantitative trait locus on Chr. 18, termed Nirep (Ohlemiller et al., Hear Res 260:47–53, 2010b). While CBA “EP susceptibility” alleles are dominant to those in B6, examination of (B6 × BALB) F1 hybrid mice and (F1 × BALB) N2 backcross mice revealed that noise-related EP reduction and associated cell pathology in BALBs are inherited in an autosomal recessive manner, and are dependent on multiple genes. Moreover, while N2 mice formed from B6 and CBA retain strong correspondence between acute EP reduction, ligament pathology, and strial pathology, N2s formed from B6 and BALB include subsets that dissociate pathology of ligament and stria. We conclude that the genes and cascades that govern the very similar EP susceptibility phenotypes in BALB and CBA mice need not be the same. BALBs appear to carry alleles that promote more pronounced long term effects of noise on the lateral wall. Separate loci in BALBs may preferentially impact stria versus ligament. PMID:20922451

  18. Vocal development and auditory perception in CBA/CaJ mice

    NASA Astrophysics Data System (ADS)

    Radziwon, Kelly E.

    Mice are useful laboratory subjects because of their small size, their modest cost, and the fact that researchers have created many different strains to study a variety of disorders. In particular, researchers have found nearly 100 naturally occurring mouse mutations with hearing impairments. For these reasons, mice have become an important model for studies of human deafness. Although much is known about the genetic makeup and physiology of the laboratory mouse, far less is known about mouse auditory behavior. To fully understand the effects of genetic mutations on hearing, it is necessary to determine the hearing abilities of these mice. Two experiments here examined various aspects of mouse auditory perception using CBA/CaJ mice, a commonly used mouse strain. The frequency difference limens experiment tested the mouse's ability to discriminate one tone from another based solely on the frequency of the tone. The mice had similar thresholds as wild mice and gerbils but needed a larger change in frequency than humans and cats. The second psychoacoustic experiment sought to determine which cue, frequency or duration, was more salient when the mice had to identify various tones. In this identification task, the mice overwhelmingly classified the tones based on frequency instead of duration, suggesting that mice are using frequency when differentiating one mouse vocalization from another. The other two experiments were more naturalistic and involved both auditory perception and mouse vocal production. Interest in mouse vocalizations is growing because of the potential for mice to become a model of human speech disorders. These experiments traced mouse vocal development from infant to adult, and they tested the mouse's preference for various vocalizations. This was the first known study to analyze the vocalizations of individual mice across development. Results showed large variation in calling rates among the three cages of adult mice but results were highly

  19. Selection of clc, cba, and fcb chlorobenzoate-catabolic genotypes from groundwater and surface waters adjacent to the Hyde Park, Niagara Falls, chemical landfill

    SciTech Connect

    Peel, M.C.; Wyndham, R.C.

    1999-04-01

    The frequency of isolation of three nonhomologous chlorobenzoate catabolic genotypes (clc, cba, and fbc) was determined for 464 isolates from freshwater sediments and groundwater in the vicinity of the Hyde Park industrial landfill site in the Niagara watershed. Samples were collected from both contaminated and noncontaminated sites during spring, summer, and fall and enriched at 4, 22, or 32 C with micromolar to millimolar concentrations of chlorobenzoates and 3-chlorobiphenyl. Hybridization at moderate stringency to restriction-digested genomic DNA with DNA probes revealed the chlorocatechol 1,2-dioxygenase operon (clcABD), the 3-chlorobenzoate 3,4-(4,5)-dioxygenase operon (cbaABC), and the 4-chlorobenzoate dehalogenase (fcbB) gene in isolates enriched from all contaminated sites in the vicinity of the industrial landfill. Nevertheless, the known genes were found in less than 10% of the isolates from the contaminated sites, indicating a high level of genetic diversity in the microbial community. The known genotypes were not enriched from the noncontaminated control sites nearby. The clc, cba, and fcb isolates were distributed across five phenotypically distinct groups based on Biolog carbon source utilization, with the breadth of the host range decreasing in the order clc > cba > fcb. Restriction fragment length polymorphism (RFLP) patterns showed that the cba genes were conserved in all isolates whereas the clc and fcb genes exhibited variation in RFLP patterns.

  20. Functional components of the bacterial CzcCBA efflux system reduce cadmium uptake and accumulation in transgenic tobacco plants.

    PubMed

    Nesler, Andrea; DalCorso, Giovanni; Fasani, Elisa; Manara, Anna; Di Sansebastiano, Gian Pietro; Argese, Emanuele; Furini, Antonella

    2017-03-25

    Cadmium (Cd) is a toxic trace element released into the environment by industrial and agricultural practices, threatening the health of plants and contaminating the food/feed chain. Biotechnology can be used to develop plant varieties with a higher capacity for Cd accumulation (for use in phytoremediation programs) or a lower capacity for Cd accumulation (to reduce Cd levels in food and feed). Here we generated transgenic tobacco plants expressing components of the Pseudomonas putida CzcCBA efflux system. Plants were transformed with combinations of the CzcC, CzcB and CzcA genes, and the impact on Cd mobilization was analysed. Plants expressing PpCzcC showed no differences in Cd accumulation, whereas those expressing PpCzcB or PpCzcA accumulated less Cd in the shoots, but more Cd in the roots. Plants expressing both PpCzcB and PpCzcA accumulated less Cd in the shoots and roots compared to controls, whereas plants expressing all three genes showed a significant reduction in Cd levels only in shoots. These results show that components of the CzcCBA system can be expressed in plants and may be useful for developing plants with a reduced capacity to accumulate Cd in the shoots, potentially reducing the toxicity of food/feed crops cultivated in Cd-contaminated soils.

  1. Loss of Myh14 Increases Susceptibility to Noise-Induced Hearing Loss in CBA/CaJ Mice

    PubMed Central

    Fu, Xiaolong; Zhang, Linqing; Jin, Yecheng; Sun, Xiaoyang; Zhang, Aizhen; Wen, Zongzhuang; Zhou, Yichen; Xia, Ming

    2016-01-01

    MYH14 is a member of the myosin family, which has been implicated in many motile processes such as ion-channel gating, organelle translocation, and the cytoskeleton rearrangement. Mutations in MYH14 lead to a DFNA4-type hearing impairment. Further evidence also shows that MYH14 is a candidate noise-induced hearing loss (NIHL) susceptible gene. However, the specific roles of MYH14 in auditory function and NIHL are not fully understood. In the present study, we used CRISPR/Cas9 technology to establish a Myh14 knockout mice line in CBA/CaJ background (now referred to as Myh14−/− mice) and clarify the role of MYH14 in the cochlea and NIHL. We found that Myh14−/− mice did not exhibit significant hearing loss until five months of age. In addition, Myh14−/− mice were more vulnerable to high intensity noise compared to control mice. More significant outer hair cell loss was observed in Myh14−/− mice than in wild type controls after acoustic trauma. Our findings suggest that Myh14 may play a beneficial role in the protection of the cochlea after acoustic overstimulation in CBA/CaJ mice. PMID:28101381

  2. Genomic and Functional Characterization of the Unusual pLOCK 0919 Plasmid Harboring the spaCBA Pili Cluster in Lactobacillus casei LOCK 0919

    PubMed Central

    Aleksandrzak-Piekarczyk, Tamara; Koryszewska-Bagińska, Anna; Grynberg, Marcin; Nowak, Adriana; Cukrowska, Bożena; Kozakova, Hana; Bardowski, Jacek

    2016-01-01

    Here, we report the extensive bioinformatic and functional analyses of the unusual pLOCK 0919, a plasmid originating from the probiotic Lactobacillus casei LOCK 0919 strain. This plasmid is atypical because it harbors the spaCBA-srtC gene cluster encoding SpaCBA pili. We show that all other spaCBA-srtC sequences of the Lactobacillus genus that have been previously described and deposited in GenBank are present in the chromosomal DNA. Another important observation for pLOCK 0919 is that the spaCBA-srtC gene cluster and its surrounding genes are highly similar to the respective DNA region that is present in the most well-known and active SpaCBA pili producer, the probiotic Lactobacillus rhamnosus GG strain. Our results demonstrate that the spaCBA-srtC clusters of pLOCK 0919 and L. rhamnosus GG are genealogically similar, located in DNA regions that are rich in transposase genes and are poorly conserved among the publicly available sequences of Lactobacillus sp. In contrast to chromosomally localized pilus gene clusters from L. casei and Lactobacillus paracasei, the plasmidic spaC of L. casei LOCK 0919 is expressed and undergoes a slight glucose-induced repression. Moreover, results of series of in vitro tests demonstrate that L. casei LOCK 0919 has an adhesion potential, which is largely determined by the presence of the pLOCK 0919 plasmid. In particular, the plasmid occurrence positively influenced the hydrophobicity and aggregation abilities of L. casei LOCK 0919. Moreover, in vivo studies indicate that among the three Lactobacillus strains used to colonize the gastrointestinal tract of germ-free mice, already after 2 days of colonization, L. casei LOCK 0919 became the dominant strain and persisted there for at least 48 days. PMID:26637469

  3. Successful associateship agreements.

    PubMed

    Crafton, B C

    1997-08-01

    When evaluating potential associateship agreements, dentists need to recognize and understand how status, noncompete clauses, scheduling and compensation affect the strength of an associateship agreement. Dentists should not enter an associateship agreement without fully understanding the agreement and its obligations or without the help of an accountant and an attorney.

  4. Variability of cytometric parameters in various clusters of interstitial endocrine cells of testicles in CBA × C57Bl6 mice during experimental chrome-benzene intoxication.

    PubMed

    Bokov, D A; Shevlyuk, N N; Abdil'danova, A M

    2014-05-01

    Chromium-benzene intoxication was associated with not only damage to tissue elements of the testicles, but also realization of the adaptive mechanisms protecting endocrine active structures in male CBA × C57Bl6 mice. Quantitative substantiation of the transformation processes, their direction, relationships, and attained levels were obtained.

  5. [Effect of age, castration and pregnancy on carcinogenesis, induced by 1,2-dimethylhydrazine, in CBA mice].

    PubMed

    Turusov, V S; Bazlova, L S; Krutovskikh, V A

    1979-05-01

    Subcutaneous injection of 1,2-dimethylhydrazine into female CBA mice once a week resulted in the development of tumours of the colon, anal region, uterus and liver. In 12-13-month-old mice treated with DMH an earlier appearance (week 8) of uterine sarcomas and more rapid increase in the incidence of tumours of the anal region were noted as compared to 3-month-old mice. In pregnant females treated with DMH a statistically significant decrease in the uterine sarcoma incidence was observed (10.3% versus 48.3% in nonpregnant). Pregnancy exerted no effect on the incidence of tumours at other sites. Castration did not affect the time of appearance and the incidence of tumours of any site.

  6. [The study of exploratory behavior in CBA/Lac male mice under influence of positive and negative social interactions].

    PubMed

    Lipina, T V; Kudriavtseva, N N

    2008-01-01

    The exploratory activity towards a new object placed in the home cage was studied in CBA/Lac male mice after their repeated daily social victories and defeats. After 10 daily social defeats, submissive mice displayed a significantly declined exploration of a new object, whereas aggressive mice with experience of 10 daily victories expressed only a mild decrease in exploratory activity (as compared to control). Twenty daily social defeats almost completely abolished exploratory behavior in submissive mice, whereas 20 daily victories resulted in the increased exploration of a new object in aggressive mice. It is suggested that repeated social defeats associated with the negative psychoemotional state lead to the development of a pronounced exploratory motivational deficit. On the other hand, the experience of repeated daily aggression forms the enhanced motivational excitement that prevents a relevant response to a neutral stimulus.

  7. Dose Optimization Study of AEOL 10150 as a Mitigator of Radiation-Induced Lung Injury in CBA/J Mice

    PubMed Central

    Murigi, Francis N.; Mohindra, Pranshu; Hung, Chiwei; Salimi, Shabnam; Goetz, Wilfried; Pavlovic, Radmila; Jackson, Isabel L.; Vujaskovic, Zeljko

    2015-01-01

    AEOL 10150 is a catalytic metalloporphyrin superoxide dismutase mimic being developed as a medical countermeasure for radiation-induced lung injury (RILI). The efficacy of AEOL 10150 against RILI through a reduction of oxidative stress, hypoxia and pro-apoptotic signals has been previously reported. The goal of this study was to determine the most effective dose of AEOL 10150 (daily subcutaneous injections, day 1–28) in improving 180-day survival in CBA/J mice after whole-thorax lung irradiation (WTLI) to a dose of 14.6 Gy. Functional and histopathological assessments were performed as secondary end points. Estimated 180-day survival improved from 10% in WTLI alone to 40% with WTLI-AEOL 10150 at 25 mg/kg (P = 0.065) and to 30% at 40 mg/kg (P = 0.023). No significant improvement was seen at doses of 5 and 10 mg/kg or at doses between 25 and 40 mg/kg. AEOL 10150 treatment at 25 mg/kg lowered the respiratory function parameter of enhanced pause (Penh) significantly, especially at week 16 and 18 (P = 0.044 and P = 0.025, respectively) compared to vehicle and other doses. Pulmonary edema/congestion were also significantly reduced at the time of necropsy among mice treated with 25 and 40 mg/kg AEOL 10150 compared to WTLI alone (P < 0.02). In conclusion, treatment with AEOL 10150 at a dose of 25 mg/kg/day for a total of 28 days starting 24 h after WTLI in CBA/J mice was found to be the optimal dose with improvement in survival and lung function. Future studies will be required to determine the optimal duration and therapeutic window for drug delivery at this dose. PMID:26414508

  8. The effect of isoflurane anaesthesia and buprenorphine on the mouse grimace scale and behaviour in CBA and DBA/2 mice.

    PubMed

    Miller, Amy; Kitson, Gemma; Skalkoyannis, Benjamin; Leach, Matthew

    2015-11-01

    Prevention or alleviation of pain in laboratory mice is a fundamental requirement of in vivo research. The mouse grimace scale (MGS) has the potential to be an effective and rapid means of assessing pain and analgesic efficacy in laboratory mice. Preliminary studies have demonstrated its potential utility for assessing pain in mouse models that involve potentially painful procedures. The next step in validation is to determine if the other procedures that are integral to these models, i.e. anaesthesia or analgesia, result in any changes in MGS score which would need to be taken into account when using this tool to assess post-procedural pain. Here, spontaneous behaviour and MGS data for CBA and DBA/2 mice were recorded at baseline and following either isoflurane anaesthesia (suitable to perform abdominal surgery) or 0.05 mg/kg s.c. buprenorphine. In line with previous studies, isoflurane anaesthesia alone had limited effects on the spontaneous behaviour in either strain of mice. Administration of buprenorphine resulted in increased periods of activity e.g. walking and chewing bedding in CBA mice. These effects were not demonstrated in DBA/2 mice. In comparison, buprenorphine alone had no impact on MGS score in either strain of mice, however DBA/2 mice showed a significant increase in MGS score following isoflurane anaesthesia. The presence of this increased MGS score must be taken into account when attempting to use the MGS to assess pain in DBA/2 mice. Further work should be carried out to establish the presence of this isoflurane effect in other strains and the potential influence of gender on the MGS. This further validation is necessary prior to implementation of this technique in clinical scenarios.

  9. Effects of chronic jet lag on the central and peripheral circadian clocks in CBA/N mice.

    PubMed

    Iwamoto, Ayaka; Kawai, Misato; Furuse, Mitsuhiro; Yasuo, Shinobu

    2014-03-01

    The disruption of the circadian clock by frequent shifts in the light-dark cycle, such as shift-work or frequent jet lag, increases the risk of many diseases, including cancer. Experimental disruption of the circadian clock also increases tumor development in mice, although most studies used the strains that are genetically impaired in melatonin synthesis and secretion. Here, we examined the effects of experimental chronic jet lag with 8 h advances of the light-dark cycle every 2 days for 10 days on the central and peripheral clocks of CBA/N mice, the strain with normal profiles of melatonin synthesis and secretion. Mice were exposed to constant darkness after the 10 days of chronic jet lag. In the suprachiasmatic nucleus (SCN), chronic jet lag shifted the temporal expression of most clock genes examined without causing total disturbance of circadian oscillations. In the liver, the temporal patterns of Per1, Bmal1, and Dbp expression were phase-shifted, and Per2 expression was significantly upregulated by chronic jet lag. Further, the expression of cell cycle-related genes, c-Myc and p53 in the liver was significantly activated by the chronic jet lag schedule with a significant positive correlation between Per2 and p53 expression. We determined the plasma concentrations of melatonin and corticosterone as candidate hormonal messengers of chronic jet lag, but their overall levels were not affected by chronic jet lag. Moreover, the expression of the MT1 melatonin and glucocorticoid receptors in the liver was suppressed by chronic jet lag. These data suggest that in CBA/N mice, frequent advances of light-dark cycles modify the phases of central clock in the SCN and disturb the peripheral clock in the liver and apoptotic functions, which may be associated with the suppression of hormone receptors.

  10. Interactions of hearing loss and Diabetes Mellitus in the middle age CBA/CaJ mouse model of presbycusis

    PubMed Central

    Vasilyeva, Olga N.; Frisina, Susan T.; Zhu, Xiaoxia; Walton, Joseph P.; Frisina, Robert D.

    2009-01-01

    Recently, we characterized the more severe nature of hearing loss in aged Type 2 diabetic human subjects. The current study prospectively assessed hearing abilities in middle age CBA/CaJ mice with Type 1 diabetes mellitus (T1DM) (STZ injection) or Type 2 diabetes mellitus (T2DM) (high fat diet), for a period of 6 months. Blood glucose, body weight and auditory tests (Auditory Brainstem Response-ABR, Distortion Product Otoacoustic Emissions-DPOAE) were evaluated at baseline and every 2 months. Tone and broadband noise-burst responses in the inferior colliculus were obtained at 6 months. Body weights of controls did not change over 6 months (~32g), but there was a significant (~5g) decline in the T1DM, while T2DM exhibited ~10g weight gain. Blood glucose levels significantly increased: 3 fold for T1DM, 1.3 fold for T2DM; with no significant changes in controls. ABR threshold elevations were found for both types of diabetes, but were most pronounced in the T2DM, starting as early as 2 months after induction of diabetes. A decline of mean DPOAE amplitudes was observed in both diabetic groups at high frequencies, and for the T2DM at low frequencies. In contrast to ABR thresholds, tone and noise thresholds in the inferior colliculus were lower for both diabetic groups. Induction of diabetes in middle-aged CBA/CaJ mice promotes amplification of age-related peripheral hearing loss which makes it a suitable model for studying the interaction of age-related hearing loss and diabetes. On the other hand, initial results of effects from very high blood glucose level (T1DM) on the auditory midbrain showed disruption of central inhibition, increased response synchrony or enhanced excitation in the inferior colliculus. PMID:19271313

  11. Selection of clc, cba, and fcb chlorobenzoate-catabolic genotypes from groundwater and surface waters adjacent to the Hyde park, Niagara Falls, chemical landfill.

    PubMed

    Peel, M C; Wyndham, R C

    1999-04-01

    The frequency of isolation of three nonhomologous chlorobenzoate catabolic genotypes (clc, cba, and fcb) was determined for 464 isolates from freshwater sediments and groundwater in the vicinity of the Hyde Park industrial landfill site in the Niagara watershed. Samples were collected from both contaminated and noncontaminated sites during spring, summer, and fall and enriched at 4, 22, or 32 degrees C with micromolar to millimolar concentrations of chlorobenzoates and 3-chlorobiphenyl (M. C. Peel and R. C. Wyndham, Microb. Ecol: 33:59-68, 1997). Hybridization at moderate stringency to restriction-digested genomic DNA with DNA probes revealed the chlorocatechol 1,2-dioxygenase operon (clcABD), the 3-chlorobenzoate 3,4-(4,5)-dioxygenase operon (cbaABC), and the 4-chlorobenzoate dehalogenase (fcbB) gene in isolates enriched from all contaminated sites in the vicinity of the industrial landfill. Nevertheless, the known genes were found in less than 10% of the isolates from the contaminated sites, indicating a high level of genetic diversity in the microbial community. The known genotypes were not enriched from the noncontaminated control sites nearby. The clc, cba, and fcb isolates were distributed across five phenotypically distinct groups based on Biolog carbon source utilization, with the breadth of the host range decreasing in the order clc > cba > fcb. Restriction fragment length polymorphism (RFLP) patterns showed that the cba genes were conserved in all isolates whereas the clc and fcb genes exhibited variation in RFLP patterns. These observations are consistent with the recent spread of the cba genes by horizontal transfer as part of transposon Tn5271 in response to contaminant exposure at Hyde Park. Consistent with this hypothesis, IS1071, the flanking element in Tn5271, was found in all isolates that carried the cba genes. Interestingly, IS1071 was also found in a high proportion of isolates from Hyde Park carrying the clc and fcb genes, as well as in type

  12. Mining agreements III

    SciTech Connect

    Not Available

    1991-01-01

    This book cover the following: Forms of mining agreements; Preliminary letter agreements; Acquisition of mineral interests involving securities; Partnership tax treatment in mining agreements; Non-tax consequences of partnerships under state law; Protection against joint venturers' liabilities; Joint venture decision making; Mining royalties; Commingling and unitization provisions; Indemnification and insurance provisions; Area of interest provision; Dispute resolution; and Non-participation and default provisions.

  13. 46 CFR 8.330 - Termination of classification society authority.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Termination of classification society authority. 8.330... classification society authority. (a) The Coast Guard may terminate an authorization agreement with a classification society if: (1) The Commandant revokes the classification society's recognition, as specified...

  14. 46 CFR 8.330 - Termination of classification society authority.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 1 2014-10-01 2014-10-01 false Termination of classification society authority. 8.330... classification society authority. (a) The Coast Guard may terminate an authorization agreement with a classification society if: (1) The Commandant revokes the classification society's recognition, as specified...

  15. 46 CFR 8.330 - Termination of classification society authority.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Termination of classification society authority. 8.330... classification society authority. (a) The Coast Guard may terminate an authorization agreement with a classification society if: (1) The Commandant revokes the classification society's recognition, as specified...

  16. 46 CFR 8.330 - Termination of classification society authority.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 1 2013-10-01 2013-10-01 false Termination of classification society authority. 8.330... classification society authority. (a) The Coast Guard may terminate an authorization agreement with a classification society if: (1) The Commandant revokes the classification society's recognition, as specified...

  17. 46 CFR 8.330 - Termination of classification society authority.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 1 2012-10-01 2012-10-01 false Termination of classification society authority. 8.330... classification society authority. (a) The Coast Guard may terminate an authorization agreement with a classification society if: (1) The Commandant revokes the classification society's recognition, as specified...

  18. Peripheral cell loss related to calcium binding protein immunocytochemistry in the dorsal cochlear nucleus in CBA/CaJ mice during aging.

    PubMed

    Idrizbegovic, E; Viberg, A; Bogdanovic, N; Canlon, B

    2001-01-01

    The influence of cochlear hair cell and spiral ganglia neuron loss on calcium binding protein immunoreactivity (calretinin, parvalbumin and calbindin) in the dorsal and posteroventral cochlear nuclei (DCN and PVCN) in CBA/CaJ (CBA) mice during aging (1-39 months) was determined. Since calcium binding proteins have buffering properties against calcium overload, they may have a protective role during aging. It is shown that the percentage of calretinin- and parvalbumin-immunopositive neurons in the DCN showed a statistically significant positive correlation with inner hair cell loss, outer hair cell loss, and spiral ganglion cell loss. A correlation was also found between aging and the auditory periphery, and calcium binding proteins in the DCN. These findings imply that the pathophysiological state of the auditory periphery may influence the neuronal homeostasis in the dorsal cochlear nucleus.

  19. Cutting Balloon Angioplasty (CBA) Versus Conventional Balloon Angioplasty (PTA) in the Pre-Dilatation of Carotid Artery Stenosis: Our Preliminary Experience

    SciTech Connect

    Cotroneo, Antonio Raffaele Iezzi, Roberto

    2007-11-15

    A retrospective study was carried out to evaluate the efficacy and safety of cutting-balloon angioplasty (CBA) for the predilatation of tight fibrocalcified carotid stenosis before carotid artery stenting (CAS). We also compared the intraprocedural results of CBA with those of conventional percutaneous transluminal angioplasty (PTA) in terms of postdilatation rate. The study population was composed of 32 patients who underwent CAS requiring predilatation before stent implantation. In detail, predilatation was performed by using a conventional balloon (PTA) in 14 patients (group A) and a cutting balloon (CBA) in 18 patients (group B). Intraprocedural and periprocedural mortality, major and minor procedural and neurologic complications, arterial damage, and embolic debris found in the distal filter were recorded. We statistically compared the rate of postdilatation obtained in the two groups. Technical success was obtained in 100% of the cases. No death, major neurologic or periprocedural complications, or arterial damage were recorded in either group. Minor neurologic reactions were recorded in 1 patient from group A (4%) and in 1 patient from group B (3%). Embolic debris was found in the distal filter in 2 patients from group A (8%) and in 3 patients from group B (10%). Postdilatation was necessary in 14 patients from group A (100%) and in 9 patients from group B (50%) (p < 0.05). Although limited to a small number of patients, compared with PTA, CBA seems to be a safe and effective procedure for the predilatation of tight fibrocalcified carotid stenoses before stent placement and may decrease the need for postdilatation in this patient population.

  20. Crystallization and X-ray Crystallographic Analysis of the Adhesive SpaC Pilin Subunit in the SpaCBA Pilus of Gut-adapted Lactobacillus rhamnosus GG.

    PubMed

    Kant, Abhiruchi; von Ossowski, Ingemar; Palva, Airi; Krishnan, Vengadesan

    2016-01-01

    Gram-positive Lactobacillus rhamnosus GG, a gut-adapted commensalic (and probiotic) strain, is known to express sortase-assembled pili on its cell surface. These SpaCBA-called pili consist of three different types of building blocks; the SpaA backbone-pilin subunit and the SpaB and SpaC ancillary pilins. SpaC is a relatively large (~90kDa) multi-domain fimbrial adhesin, and while it is located primarily at the SpaCBA pilus tip, occasionally, it can also be detected throughout the length of pilus backbone. Functionally, SpaC mainly accounts for SpaCBA pilus-mediated interactions with intestinal mucus, collagen, and human gut epithelial cells. Moreover, SpaC adhesiveness is also perceived to have a causal relationship with SpaCBA pilus-induced host-cell immune responses. In order to improve the mechanistic understanding of SpaC and its adhesive properties by structural investigation, we purified and successfully crystallized a recombinant construct of the near full-length SpaC protein (residues 36-856) in the presence of magnesium ions. X-ray diffraction data were collected to 2.6 Å resolution. The SpaC crystal belongs to the space group P21212 with unit cell parameters a = 116.5, b = 128.3, c = 136.5 Å and contains two molecules in the asymmetric unit. Presence of conserved metal ion-dependent adhesion site containing von Willebrand factor type A domain suggests its likely role in the function of SpaC.

  1. Pb-Pb dating of individual chondrules from the CBa chondrite Gujba: Assessment of the impact plume formation model

    PubMed Central

    Bollard, Jean; Connelly, James N.; Bizzarro, Martin

    2016-01-01

    The CB chondrites are metal-rich meteorites with characteristics that sharply distinguish them from other chondrite groups. Their unusual chemical and petrologic features and a young formation age of bulk chondrules dated from the CBa chondrite Gujba are interpreted to reflect a single-stage impact origin. Here, we report high-precision internal isochrons for four individual chondrules of the Gujba chondrite to probe the formation history of CB chondrites and evaluate the concordancy of relevant short-lived radionuclide chronometers. All four chondrules define a brief formation interval with a weighted mean age of 4562.49 ± 0.21 Myr, consistent with its origin from the vapor-melt impact plume generated by colliding planetesimals. Formation in a debris disk mostly devoid of nebular gas and dust sets an upper limit for the solar protoplanetary disk lifetime at 4.8 ± 0.3 Myr. Finally, given the well-behaved Pb-Pb systematics of all four chondrules, a precise formation age and the concordancy of the Mn-Cr, Hf-W, and I-Xe short-lived radionuclide relative chronometers, we propose that Gujba may serve as a suitable time anchor for these systems. PMID:27429545

  2. Economic evaluation of Australian acute care accreditation (ACCREDIT-CBA (Acute)): study protocol for a mixed-method research project

    PubMed Central

    Mumford, Virginia; Greenfield, David; Hinchcliff, Reece; Moldovan, Max; Forde, Kevin; Westbrook, Johanna I; Braithwaite, Jeffrey

    2013-01-01

    Introduction The Accreditation Collaborative for the Conduct of Research, Evaluation and Designated Investigations through Teamwork—Cost–Benefit Analysis (ACCREDIT-CBA (Acute)) study is designed to determine and make explicit the costs and benefits of Australian acute care accreditation and to determine the effectiveness of acute care accreditation in improving patient safety and quality of care. The cost–benefit analysis framework will be provided in the form of an interactive model for industry partners, health regulators and policy makers, accreditation agencies and acute care service providers. Methods and design The study will use a mixed-method approach to identify, quantify and monetise the costs and benefits of accreditation. Surveys, expert panels, focus groups, interviews and primary and secondary data analysis will be used in cross-sectional and case study designs. Ethics and dissemination The University of New South Wales Human Research Ethics Committee has approved this project (approval number HREC 10274). The results of the study will be reported via peer-reviewed publications, conferences and seminar resentations and will form part of a doctoral thesis. PMID:23396564

  3. DNA damage, cell kinetics and ODC activities studied in CBA mice exposed to electromagnetic fields generated by transmission lines.

    PubMed

    Svedenstål, B M; Johanson, K J; Mattsson, M O; Paulsson, L E

    1999-01-01

    CBA mice were exposed outdoors to 50 Hz electromagnetic fields (EMF), with a flux density of about 8 microT rms (root mean square), generated by a 220 kV transmission line. Assays were performed in order to investigate, the possible genotoxic effects after 11, 20 and 32 days of exposure, as well as the effects on body weight, leukocytes, erythrocytes, and the level of ornithine decarboxylase (ODC) activity in spleen and testis. DNA migration was studied on brain cells by single cell electrophoresis (comet assay). After 32 days of exposure a highly significant change of the tail/head ratio of the comets was observed (p < 0.001), showing DNA-damage. Further, a decreased number of mononuclear leukocytes (0.02 < p < 0.05) was observed in mice EMF-exposed for 20 days. In summary, our data indicate that transmission lines of this type may induce genotoxic effects in mice, seen as changes in the DNA migration. These results might have an important implication for health effects.

  4. Canadian Seismic Agreement

    SciTech Connect

    Wetmiller, R.J.; Lyons, J.A.; Shannon, W.E.; Munro, P.S.; Thomas, J.T.; Andrew, M.D.; Lapointe, S.P.; Lamontagne, M.; Wong, C.; Anglin, F.M.; Adams, J.; Cajka, M.G.; McNeil, W.; Drysdale, J.A. )

    1992-05-01

    This is a progress report of work carried out under the terms of a research agreement entitled the Canadian Seismic Agreement'' between the US Nuclear Regulatory Commission (USNRC), the Canadian Commercial Corporation and the Geophysics Division of the Geological Survey of Canada (GD/GSC) during the period from July 01, 1989 to June 30, 1990. The Canadian Seismic Agreement'' supports generally the operation of various seismograph stations in eastern Canada and the collection and analysis of earthquake data for the purpose of mitigating seismic hazards in eastern Canada and the northeastern US. The specific activities carried out in this one-year period are summarized below under four headings; Eastern Canada Telemetred Network and local network developments, Datalab developments, strong-motion network developments and earthquake activity. During this period the first surface fault unequivocably determined to have accompanied a historic earthquake in eastern North America, occurred in northern Quebec.

  5. FFTF Authorization Agreement

    SciTech Connect

    DAUTEL, W.A.

    2000-09-25

    The purpose of the Authorization Agreement is to serve as a mechanism whereby the U.S. Department of Energy, Richland Operations Office (RL) and Fluor Hanford (FH) jointly clarify and agree to key conditions for conducting work safely and efficiently in the Fast Flux Test Facility (FFTF). Work must be accomplished in a manner that achieves high levels of quality while protecting the environment and the safety and health of workers and the public, and complying with applicable contractual and regulatory requirements. It is the intent of this Agreement to address those items of significant importance in establishing and supporting the FFTF Authorization Envelope, but this Agreement in no way alters the terms and conditions of the Project Hanford Management Contract (PHMC), Contract Number DE-AC06-96RL13200.

  6. Classification of mental disorders*

    PubMed Central

    Stengel, E.

    1959-01-01

    One of the fundamental difficulties in devising a classification of mental disorders is the lack of agreement among psychiatrists regarding the concepts upon which it should be based: diagnoses can rarely be verified objectively and the same or similar conditions are described under a confusing variety of names. This situation militates against the ready exchange of ideas and experiences and hampers progress. As a first step towards remedying this state of affairs, the author of the article below has undertaken a critical survey of existing classifications. He shows how some of the difficulties created by lack of knowledge regarding pathology and etiology may be overcome by the use of “operational definitions” and outlines the basic principles on which he believes a generally acceptable international classification might be constructed. If this can be done it should lead to a greater measure of agreement regarding the value of specific treatments for mental disorders and greatly facilitate a broad epidemiological approach to psychiatric research. PMID:13834299

  7. The total number of neurons and calcium binding protein positive neurons during aging in the cochlear nucleus of CBA/CaJ mice: a quantitative study.

    PubMed

    Idrizbegovic, E; Canlon, B; Bross, L S; Willott, J F; Bogdanovic, N

    2001-08-01

    The quantitative stereological method, the optical fractionator, was used for determining the total number of neurons and the total number of neurons immunostained with parvalbumin, calbindin-D28k (calbindin), and calretinin in the dorsal and posteroventral cochlear nucleus (DCN and PVCN) in CBA/CaJ (CBA) mice during aging (1-39 months old). CBA mice have only a modest sensorineural pathology late in life. An age-related decrease of the total number of neurons was demonstrated in the DCN (r=-0.54, P<0.03), while the total number of neurons in the PVCN did not show any significant age-related differences (r=0.16, P=0.57). In the DCN 5.5% of neurons were parvalbumin positive in the very old (30-39 months) mice, vs. 2.2% in the 1 month old mice. In the DCN 3% of the neurons were calbindin immunopositive in the 30-39 months mice compared to 1.9% in the 1 month old group. In the PVCN, 20% of the neurons in the very old mice were parvalbumin immunopositive, compared to 12% in the young mice. Calbindin did not show any significant age-related differences in the PVCN. The total number of calretinin immunopositive neurons both in the DCN and PVCN did not show any significant change with increasing age. In conclusion, the total neuronal number in the DCN and PVCN was age-related and region-specific. While the neuronal number in the DCN and PVCN was decreased or unchanged, respectively, the calcium binding protein positive neuronal number showed a graded increase during aging in a region-specific and protein-specific manner.

  8. Discrimination between Weaned and Unweaned Atlantic Cod (Gadus morhua) in Capture-Based Aquaculture (CBA) by X-Ray Imaging and Radio-Frequency Metal Detector

    PubMed Central

    Misimi, Ekrem; Martinsen, Svein; Mathiassen, John Reidar; Erikson, Ulf

    2014-01-01

    The aim of this study was to investigate the feasibility of two detection methods for use in discrimination and sorting of adult Atlantic cod (about 2 kg) in the small scale capture-based aquaculture (CBA). Presently, there is no established method for discrimination of weaned and unweaned cod in CBA. Generally, 60–70% of the wild-caught cod in the CBA are weaned into commercial dry feed. To increase profitability for the fish farmers, unweaned cod must be separated from the stock, meaning the fish must be sorted into two groups – unweaned and weaned from moist feed. The challenges with handling of large numbers of fish in cages, defined the limits of the applied technology. As a result, a working model was established, focusing on implementing different marking materials added to the fish feed, and different technology for detecting the feed presence in the fish gut. X-ray imaging in two modes (planar and dual energy band) and sensitive radio-frequency metal detection were the detection methods that were chosen for the investigations. Both methods were tested in laboratory conditions using dead fish with marked feed inserted into the gut cavity. In particular, the sensitive radio-frequency metal detection method with carbonyl powder showed very promising results in detection of marked feed. Results show also that Dual energy band X-ray imaging may have potential for prediction of fat content in the feed. Based on the investigations it can be concluded that both X-ray imaging and sensitive radio-frequency metal detector technology have the potential for detecting cod having consumed marked feed. These are all technologies that may be adapted to large scale handling of fish from fish cages. Thus, it may be possible to discriminate between unweaned and weaned cod in a large scale grading situation. Based on the results of this study, a suggestion for evaluation of concept for in-situ sorting system is presented. PMID:24743448

  9. Discrimination between weaned and unweaned Atlantic cod (Gadus morhua) in capture-based aquaculture (CBA) by X-ray imaging and radio-frequency metal detector.

    PubMed

    Misimi, Ekrem; Martinsen, Svein; Mathiassen, John Reidar; Erikson, Ulf

    2014-01-01

    The aim of this study was to investigate the feasibility of two detection methods for use in discrimination and sorting of adult Atlantic cod (about 2 kg) in the small scale capture-based aquaculture (CBA). Presently, there is no established method for discrimination of weaned and unweaned cod in CBA. Generally, 60-70% of the wild-caught cod in the CBA are weaned into commercial dry feed. To increase profitability for the fish farmers, unweaned cod must be separated from the stock, meaning the fish must be sorted into two groups - unweaned and weaned from moist feed. The challenges with handling of large numbers of fish in cages, defined the limits of the applied technology. As a result, a working model was established, focusing on implementing different marking materials added to the fish feed, and different technology for detecting the feed presence in the fish gut. X-ray imaging in two modes (planar and dual energy band) and sensitive radio-frequency metal detection were the detection methods that were chosen for the investigations. Both methods were tested in laboratory conditions using dead fish with marked feed inserted into the gut cavity. In particular, the sensitive radio-frequency metal detection method with carbonyl powder showed very promising results in detection of marked feed. Results show also that Dual energy band X-ray imaging may have potential for prediction of fat content in the feed. Based on the investigations it can be concluded that both X-ray imaging and sensitive radio-frequency metal detector technology have the potential for detecting cod having consumed marked feed. These are all technologies that may be adapted to large scale handling of fish from fish cages. Thus, it may be possible to discriminate between unweaned and weaned cod in a large scale grading situation. Based on the results of this study, a suggestion for evaluation of concept for in-situ sorting system is presented.

  10. CD5 (Ly-1)-negative, conventional splenic B cells make a substantial contribution to the bromelain plaque-forming cell response in CBA and BW mice.

    PubMed Central

    Andrew, E M; Annis, W; Kahan, M; Maini, R N

    1990-01-01

    CD5 (Ly-1) B cells are a minor subpopulation in mouse spleen and are thought to be responsible for the production of natural autoantibodies to bromelain-treated autologous erythrocytes (Br-RBC). Here it is shown that substantial numbers of conventional, CD5-negative, splenic B cells also secrete these antibodies in CBA and (NZB x NZW)F1 mice, whereas in NZB and BALB/c mice they are all produced by the CD5 B-cell population. However, stimulation with bacterial lipopolysaccharide in vivo preferentially activates the CD5 B-cell group to anti-Br-RBC antibody secretion. PMID:1692301

  11. Countries renew rescue agreement

    NASA Astrophysics Data System (ADS)

    Bush, Susan M.

    To insure long-term continuity for the international satellite search and rescue system, COSPAS/SARSAT, an intergovernmental agreement binding the four sponsoring nations to cooperate was signed July 1 in Paris. According to Russell Vollmers of the National Oceanic and Atmospheric Administration, the agreement is binding for 15 years, with an automatic extension.The system marked the fifth anniversary of its first rescue last year, when on September 10, 1982, three persons were rescued. Begun in the 1970s by NASA as an experiment, COSPAS/SARSAT (a Russian-English acronym) is now a cooperative project among the United States, Canada, France, and the Soviet Union. Its goal is to reduce the time required to rescue air and maritime distress victims and also to locate victims who otherwise may not be found, thus using the satellite system as a life-saving device.

  12. An edit script for taxonomic classifications

    PubMed Central

    Page, Roderic DM; Valiente, Gabriel

    2005-01-01

    Background The NCBI taxonomy provides one of the most powerful ways to navigate sequence data bases but currently users are forced to formulate queries according to a single taxonomic classification. Given that there is not universal agreement on the classification of organisms, providing a single classification places constraints on the questions biologists can ask. However, maintaining multiple classifications is burdensome in the face of a constantly growing NCBI classification. Results In this paper, we present a solution to the problem of generating modifications of the NCBI taxonomy, based on the computation of an edit script that summarises the differences between two classification trees. Our algorithms find the shortest possible edit script based on the identification of all shared subtrees, and only take time quasi linear in the size of the trees because classification trees have unique node labels. Conclusion These algorithms have been recently implemented, and the software is freely available for download from . PMID:16122379

  13. 7 CFR 1007.44 - Classification of producer milk.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Classification of producer milk. 1007.44 Section 1007... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE SOUTHEAST MARKETING AREA Order Regulating Handling Classification of Milk § 1007.44 Classification of producer milk....

  14. 7 CFR 1032.44 - Classification of producer milk.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Classification of producer milk. 1032.44 Section 1032... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE CENTRAL MARKETING AREA Order Regulating Handling Classification of Milk § 1032.44 Classification of producer milk....

  15. 7 CFR 1033.44 - Classification of producer milk.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Classification of producer milk. 1033.44 Section 1033... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE MIDEAST MARKETING AREA Order Regulating Handling Classification of Milk § 1033.44 Classification of producer milk....

  16. 7 CFR 1033.44 - Classification of producer milk.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Classification of producer milk. 1033.44 Section 1033... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE MIDEAST MARKETING AREA Order Regulating Handling Classification of Milk § 1033.44 Classification of producer milk....

  17. 7 CFR 1006.44 - Classification of producer milk.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Classification of producer milk. 1006.44 Section 1006... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE FLORIDA MARKETING AREA Order Regulating Handling Classification of Milk § 1006.44 Classification of producer milk....

  18. 7 CFR 1033.44 - Classification of producer milk.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Classification of producer milk. 1033.44 Section 1033... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE MIDEAST MARKETING AREA Order Regulating Handling Classification of Milk § 1033.44 Classification of producer milk....

  19. 7 CFR 1000.44 - Classification of producer milk.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Classification of producer milk. 1000.44 Section 1000... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Classification of Milk § 1000.44 Classification of producer milk. For each...

  20. 7 CFR 1007.44 - Classification of producer milk.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Classification of producer milk. 1007.44 Section 1007... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE SOUTHEAST MARKETING AREA Order Regulating Handling Classification of Milk § 1007.44 Classification of producer milk....

  1. 7 CFR 1007.44 - Classification of producer milk.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Classification of producer milk. 1007.44 Section 1007... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE SOUTHEAST MARKETING AREA Order Regulating Handling Classification of Milk § 1007.44 Classification of producer milk....

  2. 7 CFR 1001.44 - Classification of producer milk.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Classification of producer milk. 1001.44 Section 1001... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE NORTHEAST MARKETING AREA Order Regulating Handling Classification of Milk § 1001.44 Classification of producer milk....

  3. 7 CFR 1005.44 - Classification of producer milk.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Classification of producer milk. 1005.44 Section 1005... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE APPALACHIAN MARKETING AREA Order Regulating Handling Classification of Milk § 1005.44 Classification of producer...

  4. 7 CFR 1001.44 - Classification of producer milk.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Classification of producer milk. 1001.44 Section 1001... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE NORTHEAST MARKETING AREA Order Regulating Handling Classification of Milk § 1001.44 Classification of producer milk....

  5. 7 CFR 1030.44 - Classification of producer milk.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Classification of producer milk. 1030.44 Section 1030... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE UPPER MIDWEST MARKETING AREA Order Regulating Handling Classification of Milk § 1030.44 Classification of producer...

  6. 7 CFR 1126.44 - Classification of producer milk.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Classification of producer milk. 1126.44 Section 1126... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE SOUTHWEST MARKETING AREA Order Regulating Handling Classification of Milk § 1126.44 Classification of producer milk....

  7. 7 CFR 1124.44 - Classification of producer milk.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Classification of producer milk. 1124.44 Section 1124... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE PACIFIC NORTHWEST MARKETING AREA Order Regulating Handling Classification of Milk § 1124.44 Classification of producer...

  8. 7 CFR 1124.44 - Classification of producer milk.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Classification of producer milk. 1124.44 Section 1124... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE PACIFIC NORTHWEST MARKETING AREA Order Regulating Handling Classification of Milk § 1124.44 Classification of producer...

  9. 7 CFR 1000.44 - Classification of producer milk.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Classification of producer milk. 1000.44 Section 1000... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Classification of Milk § 1000.44 Classification of producer milk. For each...

  10. 7 CFR 1131.44 - Classification of producer milk.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Classification of producer milk. 1131.44 Section 1131... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE ARIZONA MARKETING AREA Order Regulating Handling Classification of Milk § 1131.44 Classification of producer milk....

  11. 7 CFR 1131.44 - Classification of producer milk.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Classification of producer milk. 1131.44 Section 1131... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE ARIZONA MARKETING AREA Order Regulating Handling Classification of Milk § 1131.44 Classification of producer milk....

  12. 7 CFR 1005.44 - Classification of producer milk.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Classification of producer milk. 1005.44 Section 1005... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE APPALACHIAN MARKETING AREA Order Regulating Handling Classification of Milk § 1005.44 Classification of producer...

  13. 7 CFR 1032.44 - Classification of producer milk.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Classification of producer milk. 1032.44 Section 1032... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE CENTRAL MARKETING AREA Order Regulating Handling Classification of Milk § 1032.44 Classification of producer milk....

  14. 7 CFR 1030.44 - Classification of producer milk.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Classification of producer milk. 1030.44 Section 1030... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE UPPER MIDWEST MARKETING AREA Order Regulating Handling Classification of Milk § 1030.44 Classification of producer...

  15. 7 CFR 1030.44 - Classification of producer milk.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Classification of producer milk. 1030.44 Section 1030... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE UPPER MIDWEST MARKETING AREA Order Regulating Handling Classification of Milk § 1030.44 Classification of producer...

  16. 7 CFR 1126.44 - Classification of producer milk.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Classification of producer milk. 1126.44 Section 1126... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE SOUTHWEST MARKETING AREA Order Regulating Handling Classification of Milk § 1126.44 Classification of producer milk....

  17. 7 CFR 1001.44 - Classification of producer milk.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Classification of producer milk. 1001.44 Section 1001... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE NORTHEAST MARKETING AREA Order Regulating Handling Classification of Milk § 1001.44 Classification of producer milk....

  18. 7 CFR 1126.44 - Classification of producer milk.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Classification of producer milk. 1126.44 Section 1126... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE SOUTHWEST MARKETING AREA Order Regulating Handling Classification of Milk § 1126.44 Classification of producer milk....

  19. 7 CFR 1124.44 - Classification of producer milk.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Classification of producer milk. 1124.44 Section 1124... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE PACIFIC NORTHWEST MARKETING AREA Order Regulating Handling Classification of Milk § 1124.44 Classification of producer...

  20. 7 CFR 1006.44 - Classification of producer milk.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false Classification of producer milk. 1006.44 Section 1006... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE FLORIDA MARKETING AREA Order Regulating Handling Classification of Milk § 1006.44 Classification of producer milk....

  1. 7 CFR 1131.44 - Classification of producer milk.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Classification of producer milk. 1131.44 Section 1131... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE ARIZONA MARKETING AREA Order Regulating Handling Classification of Milk § 1131.44 Classification of producer milk....

  2. 7 CFR 1005.44 - Classification of producer milk.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true Classification of producer milk. 1005.44 Section 1005... SERVICE (MARKETING AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE MILK IN THE APPALACHIAN MARKETING AREA Order Regulating Handling Classification of Milk § 1005.44 Classification of producer...

  3. 7 CFR 1032.44 - Classification of producer milk.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Classification of producer milk. 1032.44 Section 1032... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE CENTRAL MARKETING AREA Order Regulating Handling Classification of Milk § 1032.44 Classification of producer milk....

  4. 7 CFR 1006.44 - Classification of producer milk.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Classification of producer milk. 1006.44 Section 1006... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE FLORIDA MARKETING AREA Order Regulating Handling Classification of Milk § 1006.44 Classification of producer milk....

  5. 7 CFR 1000.44 - Classification of producer milk.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false Classification of producer milk. 1000.44 Section 1000... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Classification of Milk § 1000.44 Classification of producer milk. For each...

  6. 46 CFR 8.450 - Termination of classification society authority.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 1 2013-10-01 2013-10-01 false Termination of classification society authority. 8.450... VESSEL INSPECTION ALTERNATIVES Alternate Compliance Program § 8.450 Termination of classification society authority. (a) The Coast Guard may terminate an authorization agreement with a classification society...

  7. 46 CFR 8.450 - Termination of classification society authority.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 1 2012-10-01 2012-10-01 false Termination of classification society authority. 8.450... VESSEL INSPECTION ALTERNATIVES Alternate Compliance Program § 8.450 Termination of classification society authority. (a) The Coast Guard may terminate an authorization agreement with a classification society...

  8. 46 CFR 8.450 - Termination of classification society authority.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 1 2014-10-01 2014-10-01 false Termination of classification society authority. 8.450... VESSEL INSPECTION ALTERNATIVES Alternate Compliance Program § 8.450 Termination of classification society authority. (a) The Coast Guard may terminate an authorization agreement with a classification society...

  9. 46 CFR 8.450 - Termination of classification society authority.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Termination of classification society authority. 8.450... VESSEL INSPECTION ALTERNATIVES Alternate Compliance Program § 8.450 Termination of classification society authority. (a) The Coast Guard may terminate an authorization agreement with a classification society...

  10. 46 CFR 8.450 - Termination of classification society authority.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Termination of classification society authority. 8.450... VESSEL INSPECTION ALTERNATIVES Alternate Compliance Program § 8.450 Termination of classification society authority. (a) The Coast Guard may terminate an authorization agreement with a classification society...

  11. 7 CFR 1005.44 - Classification of producer milk.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Classification of producer milk. 1005.44 Section 1005... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE APPALACHIAN MARKETING AREA Order Regulating Handling Classification of Milk § 1005.44 Classification of producer...

  12. 7 CFR 1007.44 - Classification of producer milk.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Classification of producer milk. 1007.44 Section 1007... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE SOUTHEAST MARKETING AREA Order Regulating Handling Classification of Milk § 1007.44 Classification of producer milk....

  13. 7 CFR 1006.44 - Classification of producer milk.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Classification of producer milk. 1006.44 Section 1006... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE FLORIDA MARKETING AREA Order Regulating Handling Classification of Milk § 1006.44 Classification of producer milk....

  14. 7 CFR 1030.44 - Classification of producer milk.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Classification of producer milk. 1030.44 Section 1030... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE UPPER MIDWEST MARKETING AREA Order Regulating Handling Classification of Milk § 1030.44 Classification of producer...

  15. 7 CFR 1131.44 - Classification of producer milk.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Classification of producer milk. 1131.44 Section 1131... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE ARIZONA MARKETING AREA Order Regulating Handling Classification of Milk § 1131.44 Classification of producer milk....

  16. 7 CFR 1124.44 - Classification of producer milk.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Classification of producer milk. 1124.44 Section 1124... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE PACIFIC NORTHWEST MARKETING AREA Order Regulating Handling Classification of Milk § 1124.44 Classification of producer...

  17. 7 CFR 1126.44 - Classification of producer milk.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Classification of producer milk. 1126.44 Section 1126... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE SOUTHWEST MARKETING AREA Order Regulating Handling Classification of Milk § 1126.44 Classification of producer milk....

  18. 7 CFR 1001.44 - Classification of producer milk.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Classification of producer milk. 1001.44 Section 1001... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE NORTHEAST MARKETING AREA Order Regulating Handling Classification of Milk § 1001.44 Classification of producer milk....

  19. 7 CFR 1033.44 - Classification of producer milk.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Classification of producer milk. 1033.44 Section 1033... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE MIDEAST MARKETING AREA Order Regulating Handling Classification of Milk § 1033.44 Classification of producer milk....

  20. 7 CFR 1032.44 - Classification of producer milk.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Classification of producer milk. 1032.44 Section 1032... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE CENTRAL MARKETING AREA Order Regulating Handling Classification of Milk § 1032.44 Classification of producer milk....

  1. 7 CFR 1000.44 - Classification of producer milk.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Classification of producer milk. 1000.44 Section 1000... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Classification of Milk § 1000.44 Classification of producer milk. For each...

  2. 7 CFR 1000.43 - General classification rules.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... protein equivalent basis. (d) Skim milk and butterfat contained in receipts of bulk concentrated fluid... Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Classification of Milk § 1000.43 General classification rules. In determining the classification of producer...

  3. 7 CFR 1126.44 - Classification of producer milk.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Classification of producer milk. 1126.44 Section 1126... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE SOUTHWEST MARKETING AREA Order Regulating Handling Classification of Milk § 1126.44 Classification of producer milk....

  4. 7 CFR 1033.44 - Classification of producer milk.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Classification of producer milk. 1033.44 Section 1033... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE MIDEAST MARKETING AREA Order Regulating Handling Classification of Milk § 1033.44 Classification of producer milk....

  5. 7 CFR 1131.44 - Classification of producer milk.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Classification of producer milk. 1131.44 Section 1131... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE ARIZONA MARKETING AREA Order Regulating Handling Classification of Milk § 1131.44 Classification of producer milk....

  6. 7 CFR 1000.44 - Classification of producer milk.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Classification of producer milk. 1000.44 Section 1000... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Classification of Milk § 1000.44 Classification of producer milk. For each...

  7. 7 CFR 1032.44 - Classification of producer milk.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Classification of producer milk. 1032.44 Section 1032... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE CENTRAL MARKETING AREA Order Regulating Handling Classification of Milk § 1032.44 Classification of producer milk....

  8. 7 CFR 1030.44 - Classification of producer milk.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Classification of producer milk. 1030.44 Section 1030... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE UPPER MIDWEST MARKETING AREA Order Regulating Handling Classification of Milk § 1030.44 Classification of producer...

  9. 7 CFR 1001.44 - Classification of producer milk.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Classification of producer milk. 1001.44 Section 1001... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE NORTHEAST MARKETING AREA Order Regulating Handling Classification of Milk § 1001.44 Classification of producer milk....

  10. 7 CFR 1005.44 - Classification of producer milk.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Classification of producer milk. 1005.44 Section 1005... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE APPALACHIAN MARKETING AREA Order Regulating Handling Classification of Milk § 1005.44 Classification of producer...

  11. 7 CFR 1006.44 - Classification of producer milk.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Classification of producer milk. 1006.44 Section 1006... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE FLORIDA MARKETING AREA Order Regulating Handling Classification of Milk § 1006.44 Classification of producer milk....

  12. 7 CFR 1007.44 - Classification of producer milk.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Classification of producer milk. 1007.44 Section 1007... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE SOUTHEAST MARKETING AREA Order Regulating Handling Classification of Milk § 1007.44 Classification of producer milk....

  13. 7 CFR 1124.44 - Classification of producer milk.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false Classification of producer milk. 1124.44 Section 1124... SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE PACIFIC NORTHWEST MARKETING AREA Order Regulating Handling Classification of Milk § 1124.44 Classification of producer...

  14. 7 CFR 1000.43 - General classification rules.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... protein equivalent basis. (d) Skim milk and butterfat contained in receipts of bulk concentrated fluid... AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Classification of Milk § 1000.43 General classification rules. In determining the classification of producer...

  15. 7 CFR 1000.43 - General classification rules.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... protein equivalent basis. (d) Skim milk and butterfat contained in receipts of bulk concentrated fluid... Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Classification of Milk § 1000.43 General classification rules. In determining the classification of producer...

  16. 7 CFR 1000.43 - General classification rules.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... protein equivalent basis. (d) Skim milk and butterfat contained in receipts of bulk concentrated fluid... AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Classification of Milk § 1000.43 General classification rules. In determining the classification of producer...

  17. Toxicological assessment of P-9801091 plant mixture extract after chronic administration in CBA/HZg mice--a biochemical and histological study.

    PubMed

    Petlevski, Roberta; Hadzija, Mirko; Slijepcević, Milivoj; Juretić, Dubravka

    2008-06-01

    Acute, subchronic and chronic effects of the P-9801091 plant mixture extract at a dose of 20 mg/kg body mass were assessed in serum of healthy CBA/HZg mice at 24 hours, 7 days, 3 months and 6 months of treatment (experimental group), and compared with the values obtained in the control group of untreated healthy CBA/HZg mice. The P-9801091 plant mixture extract is an antihyperglycemic preparation containing Myrtilli folium (Vaccinium myrtillus L.), Taraxaci radix (Taraxacum officinale Web.), Cichorii radix (Cichorium intybus L.), Juniperi fructus (Juniperus communis L.), Centaurii herba (Centaurium umbellatum Gilib.), Phaseoli fructus sine semine (Phaseolus vulgaris L.), Millefolii herba (Achillea millefolium L.), Mori folium (Morus nigra L.), Valerianae radix (Valeriana officinalis L.) and Urticae herba et radix (Urtica dioica L). Toxic effect of the P-9801091 plant mixture extract was assessed by the following biochemical parameters: urea, creatinine, aspartate aminotransferase (AST), alanine aminotransferase (ALT) and cholesterol. Also, histopathological examination of the kidneys, liver, spleen, pancreas, testes and lungs was performed. Results of biochemical testing performed at specified time points generally showed no statistically significant differences from control values, with the only exception of the catalytic concentration of AST in the experimental group measured on day 7, which was significantly increased as compared with the control group (p<0.05). Pathohistological examination including characteristic organ and tissue structure, and parenchyma relationship to the adjacent blood vessels and connective tissue in the examined organs revealed no major pathologic changes.

  18. Influence of Ganoderma lucidum (Curt.: Fr.) P. Karst. on T-cell-mediated immunity in normal and immunosuppressed mice line CBA/Ca.

    PubMed

    Nizhenkovska, Iryna V; Pidchenko, Vitalii T; Bychkova, Nina G; Bisko, Nina A; Rodnichenko, Angela Y; Kozyko, Natalya O

    2015-09-01

    The article presents the results of the investigation of the effect of biomass powder of the fungus Ganoderma lucidum on T-cell-mediated immunity in normal and immunosuppressed mice CBA/Ca. Delayed-type hypersensitivity assay was used. Experimental immunodeficiency was established with intraperitoneal injection of the immunosuppressant cyclophosphamide at a single dose of 150 mg/kg on the first day of the experiment. Results of the study show that the administration of biomass powder of Ganoderma lucidum in a dose of 0.5 mg/kg orally for 10 days increases the delayed-type hypersensitivity response in normal mice CBA/Ca. Administration of 0.5 mg/kg of biomass powder of the fungus Ganoderma lucidum for 10 days blocked the development of the T-cell-mediated immunosuppression, induced by administration of cyclophosphamide and restored the delayed-type hypersensitivity response in immunosuppressed mice. Key words: fungus Ganoderma lucidum cyclophosphamide immunodeficiency T-cell-mediated immunity delayed-type hypersensitivity.

  19. Fast rule-based bioactivity prediction using associative classification mining

    PubMed Central

    2012-01-01

    Relating chemical features to bioactivities is critical in molecular design and is used extensively in the lead discovery and optimization process. A variety of techniques from statistics, data mining and machine learning have been applied to this process. In this study, we utilize a collection of methods, called associative classification mining (ACM), which are popular in the data mining community, but so far have not been applied widely in cheminformatics. More specifically, classification based on predictive association rules (CPAR), classification based on multiple association rules (CMAR) and classification based on association rules (CBA) are employed on three datasets using various descriptor sets. Experimental evaluations on anti-tuberculosis (antiTB), mutagenicity and hERG (the human Ether-a-go-go-Related Gene) blocker datasets show that these three methods are computationally scalable and appropriate for high speed mining. Additionally, they provide comparable accuracy and efficiency to the commonly used Bayesian and support vector machines (SVM) methods, and produce highly interpretable models. PMID:23176548

  20. Automated classification of mouse pup isolation syllables: from cluster analysis to an Excel-based "mouse pup syllable classification calculator".

    PubMed

    Grimsley, Jasmine M S; Gadziola, Marie A; Wenstrup, Jeffrey J

    2012-01-01

    Mouse pups vocalize at high rates when they are cold or isolated from the nest. The proportions of each syllable type produced carry information about disease state and are being used as behavioral markers for the internal state of animals. Manual classifications of these vocalizations identified 10 syllable types based on their spectro-temporal features. However, manual classification of mouse syllables is time consuming and vulnerable to experimenter bias. This study uses an automated cluster analysis to identify acoustically distinct syllable types produced by CBA/CaJ mouse pups, and then compares the results to prior manual classification methods. The cluster analysis identified two syllable types, based on their frequency bands, that have continuous frequency-time structure, and two syllable types featuring abrupt frequency transitions. Although cluster analysis computed fewer syllable types than manual classification, the clusters represented well the probability distributions of the acoustic features within syllables. These probability distributions indicate that some of the manually classified syllable types are not statistically distinct. The characteristics of the four classified clusters were used to generate a Microsoft Excel-based mouse syllable classifier that rapidly categorizes syllables, with over a 90% match, into the syllable types determined by cluster analysis.

  1. Classification Analysis.

    ERIC Educational Resources Information Center

    Ball, Geoffrey H.

    Sorting things into groups is a basic intellectual task that allows people to simplify with minimal reduction in information. Classification techniques, which include both clustering and discrimination, provide step-by-step computer-based procedures for sorting things based on notions of generalized similarity and on the "class description"…

  2. Validation of a Systems-Actuarial Computer Process for Multidimensional Classification of Child Psychopathology.

    ERIC Educational Resources Information Center

    McDermott, Paul A.; Hale, Robert L.

    1982-01-01

    Tested diagnostic classifications of child psychopathology produced by a computerized technique known as multidimensional actuarial classification (MAC), against the criterion of expert psychological opinion. Experts' agreement with MAC was significant for all classification areas, as was MAC's agreement with the experts held as a conjoint…

  3. Mining Agreements with Indian Tribes

    ERIC Educational Resources Information Center

    Luebben, Tom

    1976-01-01

    The article discusses aspects of negotiating agreements for exploration, development, and mining of hard minerals on Indian Reservations. The agreements discussed are typical of copper agreements, but the general points under discussion are applicable to most hard minerals except for uranium, coal, and oil which are substantially different.…

  4. Agreement and Attraction in Russian

    ERIC Educational Resources Information Center

    Lorimor, Heidi; Bock, Kathryn; Zalkind, Ekaterina; Sheyman, Alina; Beard, Robert

    2008-01-01

    We assessed whether and under what conditions noncanonical agreement patterns occur in Russian, with the goal of understanding the factors involved in normal agreement. Russian is a morphosyntactically rich language in which agreement involves features for number, gender, and case. If consistent, overt specification of number and gender agreement…

  5. Agreement with Subjects in Lubukusu

    ERIC Educational Resources Information Center

    Diercks, Michael J. K.

    2010-01-01

    This dissertation examines three topics in the morphosyntax of Lubukusu (Bantu, Kenya), all of which are concerned with agreement with subjects: locative inversion, complementizer agreement, and alternative agreement effects in subject extraction. Each topic reports novel Lubukusu data which are both typologically interesting and theoretically…

  6. Roles of the espin actin-bundling proteins in the morphogenesis and stabilization of hair cell stereocilia revealed in CBA/CaJ congenic jerker mice.

    PubMed

    Sekerková, Gabriella; Richter, Claus-Peter; Bartles, James R

    2011-03-01

    Hearing and vestibular function depend on mechanosensory staircase collections of hair cell stereocilia, which are produced from microvillus-like precursors as their parallel actin bundle scaffolds increase in diameter and elongate or shorten. Hair cell stereocilia contain multiple classes of actin-bundling protein, but little is known about what each class contributes. To investigate the roles of the espin class of actin-bundling protein, we used a genetic approach that benefited from a judicious selection of mouse background strain and an examination of the effects of heterozygosity. A congenic jerker mouse line was prepared by repeated backcrossing into the inbred CBA/CaJ strain, which is known for excellent hearing and minimal age-related hearing loss. We compared stereocilia in wild-type CBA/CaJ mice, jerker homozygotes that lack espin proteins owing to a frameshift mutation in the espin gene, and jerker heterozygotes that contain reduced espin levels. The lack of espins radically impaired stereociliary morphogenesis, resulting in stereocilia that were abnormally thin and short, with reduced differential elongation to form a staircase. Mean stereociliary diameter did not increase beyond ∼0.10-0.14 µm, making stereocilia ∼30%-60% thinner than wild type and suggesting that they contained ∼50%-85% fewer actin filaments. These characteristics indicate a requirement for espins in the appositional growth and differential elongation of the stereociliary parallel actin bundle and fit the known biological activities of espins in vitro and in transfected cells. The stereocilia of jerker heterozygotes showed a transient proximal-distal tapering suggestive of haploinsufficiency and a slowing of morphogenesis that revealed previously unrecognized assembly steps and intermediates. The lack of espins also led to a region-dependent degeneration of stereocilia involving shortening and collapse. We conclude that the espin actin-bundling proteins are required for the

  7. The influence of sex on life shortening and tumor induction in CBA/Cne mice exposed to x rays or fission neutrons

    SciTech Connect

    Di Majo, V.; Coppola, M.; Rebessi, S.; Saran, A.

    1996-07-01

    An experimental study of male and female CBA/Cne mice was set up at Casaccia primarily to investigate the influence of sex on long-term survival and tumor induction after exposure to high- and low-LET radiation. Mice were whole-body-irradiated at 3 months of age with fission-neutron doses of 0.1, 0.2, 0.4, 0.8, 1.2 and 1.8 Gy at the RSV-TAPIRO reactor (mean neutron energy 0.4 MeV, in terms of kerma, y{sub D} = 51.5 KeV/{mu}m), or with 250 KVp X-ray doses of 1, 3, 5 and 7 Gy. Control and irradiated animals were then followed for their entire life span. As a general finding, male CBA/Cne mice appear more susceptible to tumori-genesis than females. In particular, the incidences of induced acute myeloid leukemia and malignant lymphomas are significant only in male mice. Benign and malignant solid tumors of many types are observed in mice of both sexes, the most frequent being in the lung, liver and ovary. However, evidence for a radiation response is limited to the case of Harderian gland neoplasms. In addition, a comparison of the observed frequency of all irradiated compared to unirradiated animals bearing solid tumors shows that the total tumor occurrence is not altered markedly by radiation exposure. A decrease in survival time is observed for both sexes and radiation types and correlates well with increasing dose. Moreover, both sex and radiation quality appear to influence the life shortening. A similar dose dependence of survival time is found when tumor-free animals alone are considered, suggesting a non-specific component of life-shortening. 18 refs., 3 figs., 5 tabs.

  8. 22 CFR 41.59 - Professionals under the North American Free Trade Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Professionals under the North American Free Trade Agreement. (a) Requirements for classification as a NAFTA... requiring employment of a person in a professional capacity consistent with NAFTA Chapter 16 Annex...

  9. 77 FR 28904 - Product Change-First-Class Package Service Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-16

    ...The Postal Service gives notice of filing a request with the Postal Regulatory Commission to add a domestic shipping services contract to the list of Negotiated Service Agreements in the Mail Classification Schedule's Competitive Products...

  10. 77 FR 28903 - Product Change-First-Class Package Service Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-16

    ...The Postal Service gives notice of filing a request with the Postal Regulatory Commission to add a domestic shipping services contract to the list of Negotiated Service Agreements in the Mail Classification Schedule's Competitive Products...

  11. Development of CAD/CAM Based Brace Models for the Treatment of Patients with Scoliosis-Classification Based Approach versus Finite Element Modelling

    PubMed Central

    Kleban, Alexander

    2015-01-01

    Study Design Retrospective controlled cohort study comparing the in-brace correction of two samples of scoliosis patients with braces of different computer aided design (CAD). Purpose In-brace correction and compliance correlate with outcome. The more standardized CAD braces that are available should enable improved in-brace correction and outcome. This study compared recent CAD brace developments with respect to in-brace corrections. Overview of Literature A 2013 randomized controlled trial demonstrated that 72% of a population complying to Scoliosis Research Society inclusion criteria on bracing did not progress using braces (mainly Boston braces) used in the United States and Canada with moderate corrective effect. Methods In-brace corrections achieved in a sample of patients fulfilling the inclusion criteria for studies on bracing using the classification based approach (CBA) were compared to the recent individual CAD/computer aided manufacturing bracing based on finite element modelling approach (FEMA). Results In-brace corrections using the different approaches differed widely. CBA in-brace corrections were 66% of the initial value. FEMA in-brace correction was 42% of the initial value. Conclusions Considering the fact that in-brace correction (and compliance) determines the end result of bracing in the treatment of scoliosis, scoliosis braces based on CBA are superior to the FEMA and the standard plaster based brace applications. PMID:26435781

  12. Analysis of thematic map classification error matrices.

    USGS Publications Warehouse

    Rosenfield, G.H.

    1986-01-01

    The classification error matrix expresses the counts of agreement and disagreement between the classified categories and their verification. Thematic mapping experiments compare variables such as multiple photointerpretation or scales of mapping, and produce one or more classification error matrices. This paper presents a tutorial to implement a typical problem of a remotely sensed data experiment for solution by the linear model method.-from Author

  13. Agreements at the Pharmaceutical/University Interface.

    ERIC Educational Resources Information Center

    Ku, Katherine

    1987-01-01

    Specific agreements that arise at the interface between universities and pharmaceutical companies are described including sponsored research agreements, license agreements, clinical study agreements, material transfer agreements, and patient consent forms with respect to commercialization rights. (Author/MLW)

  14. International Grants and Cooperative Agreements

    EPA Pesticide Factsheets

    EPA provides grants and enters into cooperative agreements that support protecting human health and the environment while advancing U.S. national interests through international environmental collaboration.

  15. Experience and grammatical agreement: statistical learning shapes number agreement production.

    PubMed

    Haskell, Todd R; Thornton, Robert; Macdonald, Maryellen C

    2010-02-01

    A robust result in research on the production of grammatical agreement is that speakers are more likely to produce an erroneous verb with phrases such as the key to the cabinets, with a singular noun followed by a plural one, than with phrases such as the keys to the cabinet, where a plural noun is followed by a singular. These asymmetries are thought to reflect core language production processes. Previous accounts have attributed error patterns to a syntactic number feature present on plurals but not singulars. An alternative approach is presented in which a process similar to structural priming contributes to the error asymmetry via speakers' past experiences with related agreement constructions. A corpus analysis and two agreement production studies test this account. The results suggest that agreement production is shaped by statistical learning from past language experience. Implications for accounts of agreement are discussed.

  16. Experience and grammatical agreement: Statistical learning shapes number agreement production

    PubMed Central

    Haskell, Todd R.; Thornton, Robert; MacDonald, Maryellen C.

    2009-01-01

    A robust result in research on the production of grammatical agreement is that speakers are more likely to produce an erroneous verb with phrases such as the key to the cabinets, with a singular noun followed by a plural one, than with phrases such as the keys to the cabinet, where a plural noun is followed by a singular. These asymmetries are thought to reflect core language production processes. Previous accounts have attributed error patterns to a syntactic number feature present on plurals but not singulars. An alternative approach is presented in which a process similar to structural priming contributes to the error asymmetry via speakers' past experiences with related agreement constructions. A corpus analysis and two agreement production studies test this account. The results suggest that agreement production is shaped by statistical learning from past language experience. Implications for accounts of agreement are discussed. PMID:19942213

  17. Agrobacterium tumefaciens Zur Regulates the High-Affinity Zinc Uptake System TroCBA and the Putative Metal Chaperone YciC, along with ZinT and ZnuABC, for Survival under Zinc-Limiting Conditions

    PubMed Central

    Chaoprasid, Paweena; Dokpikul, Thanittra; Johnrod, Jaruwan; Sirirakphaisarn, Sirin; Nookabkaew, Sumontha; Mongkolsuk, Skorn

    2016-01-01

    ABSTRACT Agrobacterium tumefaciens has a cluster of genes (Atu3178, Atu3179, and Atu3180) encoding an ABC-type transporter, here named troA, troB, and troC, respectively, which is shown here to be a zinc-specific uptake system. Reverse transcription (RT)-PCR analysis confirmed that troA, troB, and troC are cotranscribed, with troC as the first gene of the operon. The yciC (Atu3181) gene is transcribed in the opposite orientation to that of the troCBA operon and belongs to a metal-binding GTPase family. Expression of troCBA and yciC was inducible under zinc-limiting conditions and was controlled by the zinc uptake regulator, Zur. Compared to the wild type, the mutant strain lacking troC was hypersensitive to a metal chelator, EDTA, and the phenotype could be rescued by the addition of zinc, while the strain with a single yciC mutation showed no phenotype. However, yciC was important for survival under zinc limitation when either troC or zinT was inactivated. The periplasmic zinc-binding protein, ZinT, could not function when TroC was inactivated, suggesting that ZinT may interact with TroCBA in zinc uptake. Unlike many other bacteria, the ABC-type transporter ZnuABC was not the major zinc uptake system in A. tumefaciens. However, the important role of A. tumefaciens ZnuABC was revealed when TroCBA was impaired. The strain containing double mutations in the znuA and troC genes exhibited a growth defect in minimal medium. A. tumefaciens requires cooperation of zinc uptake systems and zinc chaperones, including TroCBA, ZnuABC, ZinT, and YciC, for survival under a wide range of zinc-limiting conditions. IMPORTANCE Both host and pathogen battle over access to essential metals, including zinc. In low-zinc environments, physiological responses that make it possible to acquire enough zinc are important for bacterial survival and could determine the outcome of host-pathogen interactions. A. tumefaciens was found to operate a novel pathway for zinc uptake in which Zin

  18. 78 FR 39344 - Product Change-Priority Mail Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-01

    ... Doc No: 2013-15649] POSTAL SERVICE Product Change--Priority Mail Negotiated Service Agreement AGENCY... Service Agreements in the Mail Classification Schedule's Competitive Products List. DATES: Effective date... States Postal Service to Add Priority Mail Contract 60 to Competitive Product List. Documents...

  19. 75 FR 62896 - Product Change-Priority Mail Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-13

    ... Change--Priority Mail Negotiated Service Agreement AGENCY: Postal Service. TM ACTION: Notice. SUMMARY... domestic shipping services contract to the list of Negotiated Service Agreements in the Mail Classification... Regulatory Commission a Request of the United States Postal Service to Add Priority Mail Contract 28...

  20. 78 FR 70971 - Product Change-Priority Mail Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ... Change--Priority Mail Negotiated Service Agreement AGENCY: Postal Service\\TM\\. ACTION: Notice. SUMMARY... domestic shipping services contract to the list of Negotiated Service Agreements in the Mail Classification... the Postal Regulatory Commission a Request of the United States Postal Service to Add Priority...

  1. 78 FR 70971 - Product Change-Priority Mail Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ... Change--Priority Mail Negotiated Service Agreement AGENCY: Postal Service TM . ACTION: Notice. SUMMARY... domestic shipping services contract to the list of Negotiated Service Agreements in the Mail Classification... the Postal Regulatory Commission a Request of the United States Postal Service to Add Priority...

  2. 77 FR 49032 - Product Change-Priority Mail Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ... Change--Priority Mail Negotiated Service Agreement AGENCY: Postal Service TM . ACTION: Notice. SUMMARY... domestic shipping services contract to the list of Negotiated Service Agreements in the Mail Classification... Commission a Request of the United States Postal Service to Add Priority Mail Contract 41 to...

  3. 78 FR 6360 - Product Change-Express Mail Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-30

    ... Change--Express Mail Negotiated Service Agreement AGENCY: Postal Service TM . ACTION: Notice. SUMMARY... domestic shipping services contract to the list of Negotiated Service Agreements in the Mail Classification... the Postal Regulatory Commission a Request of the United States Postal Service to Add Express...

  4. 78 FR 20361 - Product Change-Priority Mail Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-04

    ... Change--Priority Mail Negotiated Service Agreement AGENCY: Postal Service TM . ACTION: Notice. SUMMARY... domestic shipping services contract to the list of Negotiated Service Agreements in the Mail Classification... Regulatory Commission a Request of the United States Postal Service to Add Priority Mail Contract 56...

  5. 78 FR 43249 - Product Change-Priority Mail Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-19

    ... Change--Priority Mail Negotiated Service Agreement AGENCY: Postal Service TM . ACTION: Notice. SUMMARY... domestic shipping services contract to the list of Negotiated Service Agreements in the Mail Classification... Regulatory Commission a Request of the United States Postal Service to Add Priority Mail Contract 61...

  6. 77 FR 48179 - Product Change-Express Mail Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-13

    ... Change--Express Mail Negotiated Service Agreement AGENCY: Postal Service.\\TM\\ ACTION: Notice. SUMMARY... domestic shipping services contract to the list of Negotiated Service Agreements in the Mail Classification... Postal Regulatory Commission a Request of the United States Postal Service To Add Express Mail...

  7. 77 FR 48179 - Product Change-Priority Mail Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-13

    ... Change--Priority Mail Negotiated Service Agreement AGENCY: Postal Service.\\TM\\ ACTION: Notice. SUMMARY... domestic shipping services contract to the list of Negotiated Service Agreements in the Mail Classification... Postal Regulatory Commission a Request of the United States Postal Service To Add Priority Mail...

  8. 78 FR 6361 - Product Change-Priority Mail Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-30

    ... Change--Priority Mail Negotiated Service Agreement AGENCY: Postal Service TM . ACTION: Notice. SUMMARY... domestic shipping services contract to the list of Negotiated Service Agreements in the Mail Classification... the Postal Regulatory Commission a Request of the United States Postal Service to Add Priority...

  9. Remote Sensing Information Classification

    NASA Technical Reports Server (NTRS)

    Rickman, Douglas L.

    2008-01-01

    This viewgraph presentation reviews the classification of Remote Sensing data in relation to epidemiology. Classification is a way to reduce the dimensionality and precision to something a human can understand. Classification changes SCALAR data into NOMINAL data.

  10. Classification and knowledge

    NASA Technical Reports Server (NTRS)

    Kurtz, Michael J.

    1989-01-01

    Automated procedures to classify objects are discussed. The classification problem is reviewed, and the relation of epistemology and classification is considered. The classification of stellar spectra and of resolved images of galaxies is addressed.

  11. Late-occurring chromosome aberrations and global DNA methylation in hematopoietic stem/progenitor cells of CBA/CaJ mice exposed to silicon ((28)Si) ions.

    PubMed

    Rithidech, Kanokporn Noy; Honikel, Louise M; Reungpathanaphong, Paiboon; Tungjai, Montree; Jangiam, Witawat; Whorton, Elbert B

    2015-11-01

    Although myeloid leukemia (ML) is one of the major health concerns from exposure to space radiation, the risk prediction for developing ML is unsatisfactory. To increase the reliability of predicting ML risk, a much improved understanding of space radiation-induced changes in the target cells, i.e. hematopoietic stem/progenitor cells (HSPCs), is important. We focused on the in vivo induction of late-occurring damage in HSPCs of mice exposed to (28)Si ions since such damage is associated with radiation-induced genomic instability (a key event of carcinogenesis). We gave adult male CBA/CaJ mice, known to be sensitive to radiation-induced ML, a whole-body exposure (2 fractionated exposures, 15 days apart, that totaled each selected dose, delivered at the dose-rate of 1 cGy/min) to various doses of 300 MeV/n (28)Si ions, i.e. 0 (sham controls), 0.1, 0.25, or 0.5 Gy. At 6 months post-irradiation, we collected bone marrow cells from each mouse (five mice per treatment-group) for obtaining the myeloid-lineage of HSPC-derived clones for analyses. We measured the frequencies of late-occurring chromosome aberrations (CAs), using the genome-wide multicolor fluorescence in situ hybridization method. The measurement of CAs was coupled with the characterization of the global DNA methylation patterns, i.e. 5-methylcytosine (5 mC) and 5-hydroxymethylcytosine (5 hmC). A dose-dependent increase in the frequencies of CAs was detected (Analysis of Variance or ANOVA, p<0.01), indicating the induction of genomic instability after exposure of mice to 300 MeV/n (28)Si ions. Slight increases in the levels of 5 mC were observed in all treatment groups, as compared to the sham-control level. In contrast, there was a significant reduction in levels of 5 hmC (ANOVA, p<0.01). Since these endpoints were evaluated in the same mouse, our data suggested for the first time a link between a reduction in 5 hmC and genomic instability in HSPC-derived myeloid colonies of CBA/CaJ mice exposed to 300 Me

  12. Suspension agreements: The status quota

    SciTech Connect

    1996-01-01

    Since the initial filing of anti-dumping actions uranium imports from the former Soviet Union, a maze of filings, agreements, amendments, bills, measures, and deals have emerged on which only the closest observers remain current. Even with all the actions that have taken place, none of the parties appear content with the status quo and changes to the agreements are ongoing. Given this dynamic state of affairs, a recap of events and a summary of the current agreements is helpful for understanding the concerns of the involved parties and digesting future events.

  13. Federal Facility Agreement progress report

    SciTech Connect

    Not Available

    1993-10-01

    The (SRS) Federal Facility Agreement (FFA) was made effective by the US. Environmental Protection Agency Region IV (EPA) on August 16, 1993. To meet the reporting requirements in Section XXV of the Agreement, the FFA Progress Report was developed. The FFA Progress Report is the first of a series of quarterly progress reports to be prepared by the SRS. As such this report describes the information and action taken to September 30, 1993 on the SRS units identified for investigation and remediation in the Agreement. This includes; rubble pits, runoff basins, retention basin, seepage basin, burning pits, H-Area Tank 16, and spill areas.

  14. Agreement in cardiovascular risk rating based on anthropometric parameters

    PubMed Central

    Dantas, Endilly Maria da Silva; Pinto, Cristiane Jordânia; Freitas, Rodrigo Pegado de Abreu; de Medeiros, Anna Cecília Queiroz

    2015-01-01

    Objective To investigate the agreement in evaluation of risk of developing cardiovascular diseases based on anthropometric parameters in young adults. Methods The study included 406 students, measuring weight, height, and waist and neck circumferences. Waist-to-height ratio and the conicity index. The kappa coefficient was used to assess agreement in risk classification for cardiovascular diseases. The positive and negative specific agreement values were calculated as well. The Pearson chi-square (χ2) test was used to assess associations between categorical variables (p<0.05). Results The majority of the parameters assessed (44%) showed slight (k=0.21 to 0.40) and/or poor agreement (k<0.20), with low values of negative specific agreement. The best agreement was observed between waist circumference and waist-to-height ratio both for the general population (k=0.88) and between sexes (k=0.93 to 0.86). There was a significant association (p<0.001) between the risk of cardiovascular diseases and females when using waist circumference and conicity index, and with males when using neck circumference. This resulted in a wide variation in the prevalence of cardiovascular disease risk (5.5%-36.5%), depending on the parameter and the sex that was assessed. Conclusion The results indicate variability in agreement in assessing risk for cardiovascular diseases, based on anthropometric parameters, and which also seems to be influenced by sex. Further studies in the Brazilian population are required to better understand this issue. PMID:26466060

  15. 14 CFR 1274.935 - Security classification requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... requirements. Security Classification Requirements July 2002 Performance under this Cooperative Agreement will... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Security classification requirements. 1274.935 Section 1274.935 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION...

  16. 14 CFR 1274.935 - Security classification requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... requirements. Security Classification Requirements July 2002 Performance under this Cooperative Agreement will... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Security classification requirements. 1274.935 Section 1274.935 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION...

  17. Quick Guide: Power Purchase Agreements

    SciTech Connect

    2010-06-25

    Introduction to Federal power purchase agreements (PPAs), including available FEMP services and technical assistance as well as questions to ask when evaluating PPAs for a Federal renewable energy project.

  18. Pesticide Worker Safety Cooperative Agreements

    EPA Pesticide Factsheets

    The worker safety program cooperative agreements fund projects to educate pesticide applicators, handlers, and farmworkers on working safely with, and around, pesticides. Read about pesticide related grant opportunities and reports from previous grants.

  19. Good Agreements Make Good Friends

    PubMed Central

    Han, The Anh; Pereira, Luís Moniz; Santos, Francisco C.; Lenaerts, Tom

    2013-01-01

    When starting a new collaborative endeavor, it pays to establish upfront how strongly your partner commits to the common goal and what compensation can be expected in case the collaboration is violated. Diverse examples in biological and social contexts have demonstrated the pervasiveness of making prior agreements on posterior compensations, suggesting that this behavior could have been shaped by natural selection. Here, we analyze the evolutionary relevance of such a commitment strategy and relate it to the costly punishment strategy, where no prior agreements are made. We show that when the cost of arranging a commitment deal lies within certain limits, substantial levels of cooperation can be achieved. Moreover, these levels are higher than that achieved by simple costly punishment, especially when one insists on sharing the arrangement cost. Not only do we show that good agreements make good friends, agreements based on shared costs result in even better outcomes. PMID:24045873

  20. Morbidity and mortality reduction by supplemental vitamin A or beta-carotene in CBA mice given total-body gamma-radiation

    SciTech Connect

    Seifter, E.; Rettura, G.; Padawer, J.; Stratford, F.; Weinzweig, J.; Demetriou, A.A.; Levenson, S.M.

    1984-11-01

    Male CBA mice received graded doses (450-750 rad) of total-body gamma-radiation (TBR) from a dual-beam /sup 137/Cs irradiator. Commencing directly after TBR, 2 days later, or 6 days later, groups of mice received supplemental vitamin A (Vit A) or beta-carotene (beta-Car), compounds previously found to reduce radiation disease in mice subjected to partial-body X-irradiation. Given directly after TBR, supplemental Vit A decreased mortality, evidenced by increases in the radiation dose required to kill 50% of the mice within 30 days (LD50/30). In one experiment, Vit A increased the LD50/30 from 555 to 620 rad; in another experiment, Vit A increased the dose from 505 to 630 rad. Similarly, in a third experiment, supplemental beta-Car increased the LD50/30 from 510 to 645 rad. Additionally, each compound increased the survival times, even of those mice that died within 30 days. In addition to reduction of mortality and prolongation of survival time, supplemental Vit A moderated weight loss, adrenal gland hyperemia, thymus involution, and lymphopenia--all signs of radiation toxicity. Delaying the supplementation for 2 days after irradiation did not greatly reduce the efficacy of Vit A; however, delaying supplementation for 6 days decreased its effect almost completely.

  1. GolS controls the response to gold by the hierarchical induction of Salmonella-specific genes that include a CBA efflux-coding operon.

    PubMed

    Pontel, Lucas B; Audero, María E Pérez; Espariz, Martín; Checa, Susana K; Soncini, Fernando C

    2007-11-01

    Salmonella employs a specific set of proteins that allows it to detect the presence of gold salts in the environment and to mount the appropriate resistance response. This includes a P-type ATPase, GolT, and a small cytoplasmic metal binding protein, GolB. Their expression is controlled by a MerR-like sensor, GolS, which is highly selective for Au ions. Here, we identify a new GolS-controlled operon named gesABC which codes for a CBA efflux system, and establish its role in Au resistance. GesABC can also mediate drug resistance when induced by Au in a GolS-dependent manner, in a strain deleted in the main drug transporter acrAB. The GolS-controlled transcription of gesABC differs from the other GolS-regulated loci. It is activated by gold, but not induced by copper, even in a strain deleted of the main Cu transporter gene copA, which triggers a substantial GolS-dependent induction of golTS and golB. We demonstrate that the Au-dependent induction of gesABC transcription requires higher GolS levels than for the other members of the gol regulon. This correlates with a divergent GolS operator in the gesABC promoter. We propose that the hierarchical induction within the gol regulon allows Salmonella to cope with Au-contaminated environments.

  2. Leishmania amazonensis: participation of regulatory T and B cells in the in vitro priming (PIV) of CBA/J spleen cells susceptible response.

    PubMed

    Veras, Patrícia Sampaio Tavares; Welby-Borges, Marcus; de Santana, Cláudia Dias; Nihei, Jorge; Cardillo, Fabiola; de Freitas, Luiz Antônio Rodrigues

    2006-07-01

    CBA/J mice are resistant to Leishmania major and susceptible to Leishmania amazonensis. Early events determine infection outcome. Until now, PIV (in vitro priming) immune response to L. amazonensis has not been assessed. Herein, we have shown that compared to L. major, L. amazonensis induced higher parasite burden associated to similar IL-4, IFN-gamma, and TNF-alpha mRNA expressions and IFN-gamma and IL-10 levels. Although similar amounts of IL-10 were detected, the frequency of intracellular IL-10 positive B cells was enhanced in spleen cells stimulated with anti-CD3/anti-CD28, or anti-CD3/anti-CD28 and L. amazonensis, compared to L. major-stimulation. Interestingly, IL-10- producing B cells were reduced in response to anti-CD3/anti-CD28 stimulation combined with L. major compared to the other groups. L. amazonensis may favor T regulatory cell development, since 40% of all the CD4+CD25+ were CD25(high) cells. These data suggest that in PIV, susceptibility to L. amazonensis is not related to Th cell polarization, but to the presence and activity of regulatory T and B cells.

  3. Empirical agreement in model validation.

    PubMed

    Jebeile, Julie; Barberousse, Anouk

    2016-04-01

    Empirical agreement is often used as an important criterion when assessing the validity of scientific models. However, it is by no means a sufficient criterion as a model can be so adjusted as to fit available data even though it is based on hypotheses whose plausibility is known to be questionable. Our aim in this paper is to investigate into the uses of empirical agreement within the process of model validation.

  4. Classification systems for natural resource management

    USGS Publications Warehouse

    Kleckner, Richard L.

    1981-01-01

    Resource managers employ various types of resource classification systems in their management activities such as inventory, mapping, and data analysis. Classification is the ordering or arranging of objects into groups or sets on the basis of their relationships, and as such, provide the resource managers with a structure for organizing their needed information. In addition of conforming to certain logical principles, resource classifications should be flexible, widely applicable to a variety of environmental conditions, and useable with minimal training. The process of classification may be approached from the bottom up (aggregation) or the top down (subdivision) or a combination of both, depending on the purpose of the classification. Most resource classification systems in use today focus on a single resource and are used for a single, limited purpose. However, resource managers now must employ the concept of multiple use in their management activities. What they need is an integrated, ecologically based approach to resource classification which would fulfill multiple-use mandates. In an effort to achieve resource-data compatibility and data sharing among Federal agencies, and interagency agreement has been signed by five Federal agencies to coordinate and cooperate in the area of resource classification and inventory.

  5. Application Agreement and Integration Services

    NASA Technical Reports Server (NTRS)

    Driscoll, Kevin R.; Hall, Brendan; Schweiker, Kevin

    2013-01-01

    Application agreement and integration services are required by distributed, fault-tolerant, safety critical systems to assure required performance. An analysis of distributed and hierarchical agreement strategies are developed against the backdrop of observed agreement failures in fielded systems. The documented work was performed under NASA Task Order NNL10AB32T, Validation And Verification of Safety-Critical Integrated Distributed Systems Area 2. This document is intended to satisfy the requirements for deliverable 5.2.11 under Task 4.2.2.3. This report discusses the challenges of maintaining application agreement and integration services. A literature search is presented that documents previous work in the area of replica determinism. Sources of non-deterministic behavior are identified and examples are presented where system level agreement failed to be achieved. We then explore how TTEthernet services can be extended to supply some interesting application agreement frameworks. This document assumes that the reader is familiar with the TTEthernet protocol. The reader is advised to read the TTEthernet protocol standard [1] before reading this document. This document does not re-iterate the content of the standard.

  6. 15 CFR 2008.9 - Classification guides.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 3 2011-01-01 2011-01-01 false Classification guides. 2008.9 Section 2008.9 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE REGULATIONS TO IMPLEMENT E.O. 12065; OFFICE OF THE UNITED STATES...

  7. 15 CFR 2008.9 - Classification guides.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 3 2014-01-01 2014-01-01 false Classification guides. 2008.9 Section 2008.9 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE REGULATIONS TO IMPLEMENT E.O. 12065; OFFICE OF THE UNITED STATES...

  8. 15 CFR 2008.9 - Classification guides.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 3 2012-01-01 2012-01-01 false Classification guides. 2008.9 Section 2008.9 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE REGULATIONS TO IMPLEMENT E.O. 12065; OFFICE OF THE UNITED STATES...

  9. 15 CFR 2008.9 - Classification guides.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 3 2013-01-01 2013-01-01 false Classification guides. 2008.9 Section 2008.9 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE REGULATIONS TO IMPLEMENT E.O. 12065; OFFICE OF THE UNITED STATES...

  10. 15 CFR 2008.9 - Classification guides.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Classification guides. 2008.9 Section 2008.9 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE REGULATIONS TO IMPLEMENT E.O. 12065; OFFICE OF THE UNITED STATES...

  11. Lactobacillus paracasei CBA L74 Metabolic Products and Fermented Milk for Infant Formula Have Anti-Inflammatory Activity on Dendritic Cells In Vitro and Protective Effects against Colitis and an Enteric Pathogen In Vivo

    PubMed Central

    Zagato, Elena; Mileti, Erika; Massimiliano, Lucia; Fasano, Francesca; Budelli, Andrea; Penna, Giuseppe; Rescigno, Maria

    2014-01-01

    The rapid expansion of commercially available fermented food products raises important safety issues particularly when infant food is concerned. In many cases, the activity of the microorganisms used for fermentation as well as what will be the immunological outcome of fermented food intake is not known. In this manuscript we used complex in vitro, ex-vivo and in vivo systems to study the immunomodulatory properties of probiotic-fermented products (culture supernatant and fermented milk without live bacteria to be used in infant formula). We found in vitro and ex-vivo that fermented products of Lactobacillus paracasei CBA L74 act via the inhibition of proinflammatory cytokine release leaving anti-inflammatory cytokines either unaffected or even increased in response to Salmonella typhimurium. These activities are not dependent on the inactivated bacteria but to metabolic products released during the fermentation process. We also show that our in vitro systems are predictive of an in vivo efficacy by the fermented products. Indeed CBA L74 fermented products (both culture medium and fermented milk) could protect against colitis and against an enteric pathogen infection (Salmonella typhimurium). Hence we found that fermented products can act via the inhibition of immune cell inflammation and can protect the host from pathobionts and enteric pathogens. These results open new perspectives in infant nutrition and suggest that L. paracasei CBA L74 fermented formula can provide immune benefits to formula-fed infants, without carrying live bacteria that may be potentially dangerous to an immature infant immune system. PMID:24520333

  12. Lactobacillus paracasei CBA L74 metabolic products and fermented milk for infant formula have anti-inflammatory activity on dendritic cells in vitro and protective effects against colitis and an enteric pathogen in vivo.

    PubMed

    Zagato, Elena; Mileti, Erika; Massimiliano, Lucia; Fasano, Francesca; Budelli, Andrea; Penna, Giuseppe; Rescigno, Maria

    2014-01-01

    The rapid expansion of commercially available fermented food products raises important safety issues particularly when infant food is concerned. In many cases, the activity of the microorganisms used for fermentation as well as what will be the immunological outcome of fermented food intake is not known. In this manuscript we used complex in vitro, ex-vivo and in vivo systems to study the immunomodulatory properties of probiotic-fermented products (culture supernatant and fermented milk without live bacteria to be used in infant formula). We found in vitro and ex-vivo that fermented products of Lactobacillus paracasei CBA L74 act via the inhibition of proinflammatory cytokine release leaving anti-inflammatory cytokines either unaffected or even increased in response to Salmonella typhimurium. These activities are not dependent on the inactivated bacteria but to metabolic products released during the fermentation process. We also show that our in vitro systems are predictive of an in vivo efficacy by the fermented products. Indeed CBA L74 fermented products (both culture medium and fermented milk) could protect against colitis and against an enteric pathogen infection (Salmonella typhimurium). Hence we found that fermented products can act via the inhibition of immune cell inflammation and can protect the host from pathobionts and enteric pathogens. These results open new perspectives in infant nutrition and suggest that L. paracasei CBA L74 fermented formula can provide immune benefits to formula-fed infants, without carrying live bacteria that may be potentially dangerous to an immature infant immune system.

  13. Gender agreement and multiple referents.

    PubMed

    Finocchiaro, Chiara; Mahon, Bradford Z; Caramazza, Alfonso

    2008-01-01

    We report a new pattern of usage in current, spoken Italian that has implications for both psycholinguistic models of language production and linguistic theories of language change. In Italian, gender agreement is mandatory for both singular and plural nouns. However, when two or more nouns of different grammatical gender appear in a conjoined noun phrase (NP), masculine plural agreement is required. In this study, we combined on-line and off-line methodologies in order to assess the mechanisms involved in gender marking in the context of multiple referents. The results of two pronoun production tasks showed that plural feminine agreement was significantly more difficult than plural masculine agreement. In a separate study using offline judgements of acceptability, we found that agreement violations in Italian are tolerated more readily in the case of feminine conjoined noun phrases (e.g., la mela e la banana 'the:fem apple:fem and the: fem banana: fem') than masculine conjoined noun phrases (e.g., il fiore e il libro 'the:mas flower: mas and the:mas book:mas'). Implications of these results are discussed both at the level of functional architecture within the language production system and at the level of changes in language use.

  14. Gender agreement and multiple referents

    PubMed Central

    Finocchiaro, Chiara; Mahon, Bradford Z.; Caramazza, Alfonso

    2010-01-01

    We report a new pattern of usage in current, spoken Italian that has implications for both psycholinguistic models of language production and linguistic theories of language change. In Italian, gender agreement is mandatory for both singular and plural nouns. However, when two or more nouns of different grammatical gender appear in a conjoined noun phrase (NP), masculine plural agreement is required. In this study, we combined on-line and off-line methodologies in order to assess the mechanisms involved in gender marking in the context of multiple referents. The results of two pronoun production tasks showed that plural feminine agreement was significantly more difficult than plural masculine agreement. In a separate study using offline judgements of acceptability, we found that agreement violations in Italian are tolerated more readily in the case of feminine conjoined noun phrases (e.g., la mela e la banana ‘the:fem apple:fem and the: fem banana: fem’) than masculine conjoined noun phrases (e.g., il fiore e il libro ‘the:mas flower: mas and the:mas book:mas’). Implications of these results are discussed both at the level of functional architecture within the language production system and at the level of changes in language use.* PMID:21037930

  15. Care management: agreement between nursing prescriptions and patients' care needs

    PubMed Central

    Faeda, Marília Silveira; Perroca, Márcia Galan

    2016-01-01

    ABSTRACT Objectives: analyze agreement between nursing prescriptions recorded in medical files and patients' care needs; investigate the correlation between the nurses' professional background and agreement of prescriptions. Method: descriptive study with quantitative and documentary approach conducted in the medical clinic, surgical, and specialized units of a university hospital in the interior of São Paulo, Brazil. The new validated version of a Patient Classification Instrument was used and 380 nursing prescriptions written at the times of hospital admission and discharge were assessed. Results: 75% of the nursing prescriptions items were compatible with the patients' care needs. Only low correlation between nursing prescription agreement and professional background was found. Conclusion: the nursing prescriptions did not fully meet the care needs of patients. The care context and work process should be analyzed to enable more effective prescriptions, while strategies to assess the care needs of patients are recommended. PMID:27508902

  16. Experience and Grammatical Agreement: Statistical Learning Shapes Number Agreement Production

    ERIC Educational Resources Information Center

    Haskell, Todd R.; Thornton, Robert; MacDonald, Maryellen C.

    2010-01-01

    A robust result in research on the production of grammatical agreement is that speakers are more likely to produce an erroneous verb with phrases such as "the key to the cabinets", with a singular noun followed by a plural one, than with phrases such as "the keys to the cabinet", where a plural noun is followed by a singular. These asymmetries are…

  17. Bayesian inference for agreement measures.

    PubMed

    Vidal, Ignacio; de Castro, Mário

    2016-08-25

    The agreement of different measurement methods is an important issue in several disciplines like, for example, Medicine, Metrology, and Engineering. In this article, some agreement measures, common in the literature, were analyzed from a Bayesian point of view. Posterior inferences for such agreement measures were obtained based on well-known Bayesian inference procedures for the bivariate normal distribution. As a consequence, a general, simple, and effective method is presented, which does not require Markov Chain Monte Carlo methods and can be applied considering a great variety of prior distributions. Illustratively, the method was exemplified using five objective priors for the bivariate normal distribution. A tool for assessing the adequacy of the model is discussed. Results from a simulation study and an application to a real dataset are also reported.

  18. River Sinuosity Classification - The method

    NASA Astrophysics Data System (ADS)

    Petrovszki, J.; Székely, B.; Timár, G.

    2012-04-01

    We introduced a new evaluation method, the classification of multiple window-size based sinuosity spectrum. If the river is long enough for the analysis, the classification could be as useful, as the sinuosity spectrum, but sometimes it is more straightforward. Furthermore, for the classification, we did not need the main parameters of the river, e.g. the bankfull discharge. Each sinuosity calculation that was performed for a given window size, has been considered as one band (one channel) of a multichannel "image". Then, the sinuosity spectrums became multichannel images are of size 1 X N where N represents the length of the actual river in pixels. Using this multichannel input unsupervised ISOCLASS classification was carried out on these data, using ER Mapper software. The requested number of classes was set to 5. The results of the sinuosity calculations are scalars. Earlier, it was a subjective decision to divide the sinuosity values into the categories (low, medium-low, medium, medium-high, and high), while the new method provides integer numbers (1 to 5) itself. These numbers are calculated from the sinuosity values, but are not equal to them. Analysing the results of the classification, it is important to note that the method typically splits the river course into contiguous sections that belong to the same class. Boundaries of these classes can be considered as points of considerable change in the river course, because the method uses statistically relevant amount of data of the river course in a robust way to detect changes. Some specific classes or their boundaries seem to be correlated to tectonically active zones. The research is made in the frame of project OTKA-NK83400 (SourceSink Hungary). The European Union and the European Social Fund also have provided financial support to the project under the grant agreement no. TÁMOP 4.2.1./B-09/1/KMR-2010-0003.

  19. Interrater agreement for Critical Care EEG Terminology

    PubMed Central

    Gaspard, Nicolas; Hirsch, Lawrence J.; LaRoche, Suzette M.; Hahn, Cecil D.; Westover, M. Brandon

    2016-01-01

    Summary Objective The interpretation of critical care electroencephalography (EEG) studies is challenging because of the presence of many periodic and rhythmic patterns of uncertain clinical significance. Defining the clinical significance of these patterns requires standardized terminology with high interrater agreement (IRA). We sought to evaluate IRA for the final, published American Clinical Neurophysiology Society (ACNS)–approved version of the critical care EEG terminology (2012 version). Our evaluation included terms not assessed previously and incorporated raters with a broad range of EEG reading experience. Methods After reviewing a set of training slides, 49 readers independently completed a Web-based test consisting of 11 identical questions for each of 37 EEG samples (407 questions). Questions assessed whether a pattern was an electrographic seizure; pattern location (main term 1), pattern type (main term 2); and presence and classification of eight other key features (“plus” modifiers, sharpness, absolute and relative amplitude, frequency, number of phases, fluctuation/evolution, and the presence of “triphasic” morphology). Results IRA statistics (κ values) were almost perfect (90–100%) for seizures, main terms 1 and 2, the +S modifier (superimposed spikes/sharp waves or sharply contoured rhythmic delta activity), sharpness, absolute amplitude, frequency, and number of phases. Agreement was substantial for the +F (superimposed fast activity) and +R (superimposed rhythmic delta activity) modifiers (66% and 67%, respectively), moderate for triphasic morphology (58%), and fair for evolution (21%). Significance IRA for most terms in the ACNS critical care EEG terminology is high. These terms are suitable for multicenter research on the clinical significance of critical care EEG patterns. PMID:24888711

  20. Unilateral T cell maturation arrest in the thymus of CBA/H mice as a long-term effect after neutron irradiation

    SciTech Connect

    Huiskamp, R.; van Ewijk, W.

    1987-04-01

    Thymuses of CBA/H mice were investigated up to 570 days after whole-body irradiation with 2.5 Gy fast fission neutrons or 6.0 Gy X rays. A number of these thymuses, observed 220-270 days after neutron irradiation, have two equal sized lobes, one of which has an abnormal T cell distribution. The present paper reports on the distribution of lymphoid and stromal cell types in these thymuses. For this purpose, we employed immunohistology using the indirect immunoperoxidase method. We incubated frozen sections of these aberrant thymuses with monoclonal antibodies directed to cell surface differentiation antigens on lymphoid cells, such as Thy-1, T-200, MT-4, Lyt-1, Lyt-2, and MEL-14; monoclonal antibodies directed to major histocompatibility complex (MHC) antigens, such as I-A and H-2K; and monoclonal antibodies directed to determinants in various thymic stromal cell types. The results of this study show a T cell differentiation arrest in only one of the two thymic lobes. T cells in the aberrant lobe express Thy-1, T-200, and MEL-14 antigens but are MT-4- and Lyt-1-. In some lobes, a weak Lyt-2 expression was observed. The observed T cell maturation arrest is mainly restricted to the cortex since in the medulla, in addition to cells with an aberrant cortical phenotype, normal T cell phenotypes are observed. This indicates that cortex and medulla have independent generation kinetics in T cell maturation. The stromal cell composition in these abnormal lobes is not different from that in the normal lobe, but the size of the medulla tends to be smaller. Furthermore, the I-A expression on the cortical epithelial cells does not reveal the characteristic reticular staining pattern that is observed in the normal lobe, since the I-A determinants are not strictly confined to the epithelial cells.

  1. University of Scranton: Master Agreement.

    ERIC Educational Resources Information Center

    Scranton Univ., PA.

    This document is the collective bargaining agreement between the University of Scranton and its faculty effective September 1, 1975 until August 31, 1976. Its provisions include all full-time faculty members associated with the Reading Clinic and Counseling Center, full-time faculty assigned to the Department of Physical Education, full-time…

  2. Block Transfer Agreement Evaluation Project

    ERIC Educational Resources Information Center

    Bastedo, Helena

    2010-01-01

    The objective of this project is to evaluate for the British Columbia Council on Admissions and Transfer (BCCAT) the effectiveness of block transfer agreements (BTAs) in the BC Transfer System and recommend steps to be taken to improve their effectiveness. Findings of this study revealed that institutions want to expand block credit transfer;…

  3. Form 6 - gas balancing agreement

    SciTech Connect

    Not Available

    1990-01-01

    In 1988, a special Committee of the Rocky Mountain Mineral Law Foundation undertook a project to draft a model from gas balancing agreement. This project was initiated at the request of a number of Foundation members who felt that a model form gas balancing agreement would facilitate the negotiation of operating agreement, since gas balancing issues had become sticking points in the process. The Committee was composed of attorneys representing a wide cross-section of the oil and gas industry including both major and independent oil companies, production companies with interstate pipeline affiliates, and private practitioners. The Committee attempted to address the more controversial issues in gas balancing with optional provisions in the Form. To facilitate the negotiation process, the number of optional provisions was minimized. This form may be used as an Appendix to the new A.A.P.L. Form 610-1989 Model Form Operating Agreement. This book includes provision of this Form which are: Ownership of gas production; Balancing of production accounts; Cash balancing upon depletion; Deliverability tests; Nominations; Statements; Payment of taxes; Operating expenses; Overproducing allowable; Payment of leasehold burdens; Operator's liability; Successors and assigns; Audits; Arbitration; and Operator's fees.

  4. 29 CFR 1908.10 - Cooperative Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 5 2010-07-01 2010-07-01 false Cooperative Agreements. 1908.10 Section 1908.10 Labor... CONSULTATION AGREEMENTS § 1908.10 Cooperative Agreements. (a) Who may make Agreements. The Assistant Secretary may make a Cooperative Agreement under this part with the Governor of a State or with any State...

  5. 29 CFR 1908.10 - Cooperative Agreements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 5 2012-07-01 2012-07-01 false Cooperative Agreements. 1908.10 Section 1908.10 Labor... CONSULTATION AGREEMENTS § 1908.10 Cooperative Agreements. (a) Who may make Agreements. The Assistant Secretary may make a Cooperative Agreement under this part with the Governor of a State or with any State...

  6. 29 CFR 1908.10 - Cooperative Agreements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 5 2011-07-01 2011-07-01 false Cooperative Agreements. 1908.10 Section 1908.10 Labor... CONSULTATION AGREEMENTS § 1908.10 Cooperative Agreements. (a) Who may make Agreements. The Assistant Secretary may make a Cooperative Agreement under this part with the Governor of a State or with any State...

  7. 2 CFR 1401.220 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Cooperative agreement. 1401.220 Section 1401....220 Cooperative agreement. Cooperative agreement means an award of financial assistance that... include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  8. 29 CFR 1908.10 - Cooperative Agreements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 5 2014-07-01 2014-07-01 false Cooperative Agreements. 1908.10 Section 1908.10 Labor... CONSULTATION AGREEMENTS § 1908.10 Cooperative Agreements. (a) Who may make Agreements. The Assistant Secretary may make a Cooperative Agreement under this part with the Governor of a State or with any State...

  9. 29 CFR 1908.10 - Cooperative Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 5 2013-07-01 2013-07-01 false Cooperative Agreements. 1908.10 Section 1908.10 Labor... CONSULTATION AGREEMENTS § 1908.10 Cooperative Agreements. (a) Who may make Agreements. The Assistant Secretary may make a Cooperative Agreement under this part with the Governor of a State or with any State...

  10. 2 CFR 182.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Cooperative agreement. 182.620 Section 182... § 182.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  11. Retrospective observational study comparing the international hip dysplasia institute classification with the Tonnis classification of developmental dysplasia of the hip

    PubMed Central

    Miao, Mingyuan; Cai, Haiqing; Hu, Liwei; Wang, Zhigang

    2017-01-01

    Abstract The Tonnis radiographic classification of developmental dysplasia of the hip (DDH) has been widely used. The International Hip Dysplasia Institute (IHDI) classification, a new classification system recently developed by the IHDI, is beginning to be applied to evaluate DDH with the absence of an ossification center. This study aimed to validate its reliability in evaluating DDH with an ossification center and compared the 2 classifications in evaluating all DDH hips. In addition, the prediction values of the 2 classifications on clinical management selection were compared. In total, the pelvic radiographs of 212 DDH patients (318 hips) between the ages of 6 and 48 months admitted to Shanghai Children's Medical Center between 2007 and 2014 were assessed by 3 observers retrospectively using the 2 classifications. Intraobserver and interobserver agreements were evaluated using the kappa method. We also assessed the correlation of the 2 radiographic classifications in terms of treatment selection. In total, 216 hips received closed reduction, 61 hips received open reduction, and 41 hips received pelvic osteotomy. Both classifications showed excellent intraobserver and interobserver reliability. However, the IHDI demonstrated more interobserver reliability, especially for evaluating DDH without an ossification center. Both classifications were found to be relevant in detecting the DDH treatment type (P < 0.01). The Tonnis classification was also relevant, especially for evaluating DDH with an ossification center. The IHDI classification exhibited good practicability in classifying the radiographic severity of DDH compared to the Tonnis classification, particularly in hips without an ossification center. Like the Tonnis classification, the IHDI classification can predict treatment plans. Therefore, the IHDI classification seems to be the upgraded version of the Tonnis classification. PMID:28099350

  12. Classification Shell Game.

    ERIC Educational Resources Information Center

    Etzold, Carol

    1983-01-01

    Discusses shell classification exercises. Through keying students advanced from the "I know what a shell looks like" stage to become involved in the classification process: observing, labeling, making decisions about categories, and identifying marine animals. (Author/JN)

  13. Limiting technology by negotiated agreement

    SciTech Connect

    Carnesale, A.

    1983-01-01

    The author concentrates on anti-ballistic missile (ABM) systems as an example of a continuing effort to limit technology by negotiated agreement. He first discusses the ABM treaty of 1972, ratified by both the US and the USSR. Afterwards, he briefly treats each of the following: ballistic missile defense (BMD) dilemmas; nature of the BMD choice; technology; economics; deterrence; nuclear warfighting; relations with allies; arms control; Star Wars; and on limiting technology.

  14. 77 FR 32115 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ... Agreement Western Mediterranean-U.S. East Coast. Parties: CMA CGM, S.A. and A.P. Moller-Maersk A/S. Filing.... Synopsis: The amendment would add Morocco to the geographic scope of the agreement. Agreement No.:...

  15. 48 CFR 842.1203 - Processing agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Novation and Change-of-Name Agreements 842.1203 Processing agreements. Before execution of novation and change-of-name agreements, contracting officers...

  16. 48 CFR 842.1203 - Processing agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Novation and Change-of-Name Agreements 842.1203 Processing agreements. Before execution of novation and change-of-name agreements, contracting officers...

  17. 78 FR 15951 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-13

    ... agreement. Agreement No.: 012196. Title: MSC/CSAV Ecuador--North Europe Vessel Sharing Agreement. Parties... on the U.S. East Coast on the one hand, and from ports on the U.S. East Coast to Panama and...

  18. 76 FR 20668 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    ... amendment deletes Hanjin Shipping as a party to the Agreement. Agreement No.: 012105-001. Title: SCM Lines Transportes/CCNI Agreement. Parties: Compania Chilena de Navegacion Interoceanica S.A. and SCM...

  19. Gastritis staging: interobserver agreement by applying OLGA and OLGIM systems.

    PubMed

    Isajevs, Sergejs; Liepniece-Karele, Inta; Janciauskas, Dainius; Moisejevs, Georgijs; Putnins, Viesturs; Funka, Konrads; Kikuste, Ilze; Vanags, Aigars; Tolmanis, Ivars; Leja, Marcis

    2014-04-01

    Atrophic gastritis remains a difficult histopathological diagnosis with low interobserver agreement. The aim of our study was to compare gastritis staging and interobserver agreement between general and expert gastrointestinal (GI) pathologists using Operative Link for Gastritis Assessment (OLGA) and Operative Link on Gastric Intestinal Metaplasia (OLGIM). We enrolled 835 patients undergoing upper endoscopy in the study. Two general and two expert gastrointestinal pathologists graded biopsy specimens according to the Sydney classification, and the stage of gastritis was assessed by OLGA and OLGIM system. Using OLGA, 280 (33.4 %) patients had gastritis (stage I-IV), whereas with OLGIM this was 167 (19.9 %). OLGA stage III- IV gastritis was observed in 25 patients, whereas by OLGIM stage III-IV was found in 23 patients. Interobserver agreement between expert GI pathologists for atrophy in the antrum, incisura angularis, and corpus was moderate (kappa = 0.53, 0.57 and 0.41, respectively, p < 0.0001), but almost perfect for intestinal metaplasia (kappa = 0.82, 0.80 and 0.81, respectively, p < 0.0001). However, interobserver agreement between general pathologists was poor for atrophy, but moderate for intestinal metaplasia. OLGIM staging provided the highest interobserver agreement, but a substantial proportion of potentially high-risk individuals would be missed if only OLGIM staging is applied. Therefore, we recommend to use a combination of OLGA and OLGIM for staging of chronic gastritis.

  20. Contracting for professional service agreements.

    PubMed

    Berman, M L

    1995-08-01

    A review of several professional service agreements (PSA) of managed care organizations which contract with gynecologic oncologists in the Southern California area demonstrates several distinct patterns of practice restrictions and financial benefits which can help guide the physician who is considering signing such an agreement. These contracts must be evaluated in a manner similar to any business transaction as they are legally binding and can enhance or adversely impact one's clinical practice. Their advantages include increased numbers of referrals resulting in higher practice income; however, their disadvantages include practice restrictions which can adversely impact office overhead, practice efficiency, and the ability to deliver quality medical care. General guidelines to physicians evaluating a PSA include (1) avoiding "hold harmless" clauses, (2) avoiding contracts which tie enrollment in one plan to others, (3) the need to enter any verbal agreements by managed care administrators into the contract language, and (4) avoidance of actions which might be construed as being in violation of antitrust activities. Furthermore, physicians must avoid contracts which will result in the uncontrolled growth of a practice beyond its capabilities for expansion.

  1. 40 CFR 35.1615 - Substate agreements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... agencies. The agreement shall be developed, administered and approved in accordance with the provisions of... this subchapter. The agreement shall specify outputs, milestone schedule, and the budget required...

  2. 46 CFR 8.130 - Agreement conditions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... certificates issued by, an authorized classification society will be accepted as functions performed by, or certificates issued by, the Coast Guard, provided that the classification society maintains compliance with all... classification society authorizing the performance of delegated functions will be written and will require...

  3. 46 CFR 8.130 - Agreement conditions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... certificates issued by, an authorized classification society will be accepted as functions performed by, or certificates issued by, the Coast Guard, provided that the classification society maintains compliance with all... classification society authorizing the performance of delegated functions will be written and will require...

  4. Citrate utilization by Corynebacterium glutamicum is controlled by the CitAB two-component system through positive regulation of the citrate transport genes citH and tctCBA.

    PubMed

    Brocker, Melanie; Schaffer, Steffen; Mack, Christina; Bott, Michael

    2009-06-01

    In this work, the molecular basis of aerobic citrate utilization by the gram-positive bacterium Corynebacterium glutamicum was studied. Genome analysis revealed the presence of two putative citrate transport systems. The permease encoded by citH belongs to the citrate-Mg(2+):H(+)/citrate-Ca(2+):H(+) symporter family, whereas the permease encoded by the tctCBA operon is a member of the tripartite tricarboxylate transporter family. The expression of citH or tctCBA in Escherichia coli enabled this species to utilize citrate aerobically, indicating that both CitH and TctABC are functional citrate transporters. Growth tests with the recombinant E. coli strains indicated that CitH is active with Ca(2+) or Sr(2+) but not with Mg(2+) and that TctABC is active with Ca(2+) or Mg(2+) but not with Sr(2+). We could subsequently show that, with 50 mM citrate as the sole carbon and energy source, the C. glutamicum wild type grew best when the minimal medium was supplemented with CaCl(2) but that MgCl(2) and SrCl(2) also supported growth. Each of the two transporters alone was sufficient for growth on citrate. The expression of citH and tctCBA was activated by citrate in the growth medium, independent of the presence or absence of glucose. This activation was dependent on the two-component signal transduction system CitAB, composed of the sensor kinase CitA and the response regulator CitB. CitAB belongs to the CitAB/DcuSR family of two-component systems, whose members control the expression of genes that are involved in the transport and catabolism of tricarboxylates or dicarboxylates. C. glutamicum CitAB is the first member of this family studied in Actinobacteria.

  5. Induction of Chronic Inflammation and Altered Levels of DNA Hydroxymethylation in Somatic and Germinal Tissues of CBA/CaJ Mice Exposed to 48Ti Ions

    PubMed Central

    Rithidech, Kanokporn Noy; Jangiam, Witawat; Tungjai, Montree; Gordon, Chris; Honikel, Louise; Whorton, Elbert B.

    2016-01-01

    Although the lung is one of the target organs at risk for cancer induction from exposure to heavy ions found in space, information is insufficient on cellular/molecular responses linked to increased cancer risk. Knowledge of such events may aid in the development of new preventive measures. Furthermore, although it is known that germinal cells are sensitive to X- or γ-rays, there is little information on the effects of heavy ions on germinal cells. Our goal was to investigate in vivo effects of 1 GeV/n 48Ti ions (one of the important heavy ions found in the space environment) on somatic (lung) and germinal (testis) tissues collected at various times after a whole body irradiation of CBA/CaJ mice (0, 0.1, 0.25, or 0.5 Gy, delivered at 1 cGy/min). We hypothesized that 48Ti-ion-exposure induced damage in both tissues. Lung tissue was collected from each mouse from each treatment group at 1 week, 1 month, and 6 months postirradiation. For the testis, we collected samples at 6 months postirradiation. Hence, only late-occurring effects of 48Ti ions in the testis were studied. There were five mice per treatment group at each harvest time. We investigated inflammatory responses after exposure to 48Ti ions by measuring the levels of activated nuclear factor kappa B and selected pro-inflammatory cytokines in both tissues of the same mouse. These measurements were coupled with the quantitation of the levels of global 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC). Our data clearly showed the induction of chronic inflammation in both tissues of exposed mice. A dose-dependent reduction in global 5hmC was found in the lung at all time-points and in testes collected at 6 months postirradiation. In contrast, significant increases in global 5mC were found only in lung and testes collected at 6 months postirradiation from mice exposed to 0.5 Gy of 1 GeV/n 48Ti ions. Overall, our data showed that 48Ti ions may create health risks in both lung and

  6. Relative toxicity of chronic irradiation by 45Ca beta particles and 242Cm alpha particles with respect to the production of lung tumors in CBA/Ca mice.

    PubMed

    Priest, N D; Hoel, D G; Brooks, P N

    2006-11-01

    Approximately 1800 female CBA/Ca mice were exposed by inhalation at three dose levels to beta particles from (45)Ca-labeled fused aluminosilicate particles (FAP), to alpha particles from (242)Cm-labeled FAP, or to carrier control FAP. Another group of mice inhaled no FAP and were designated as untreated cage controls. The FAP in combination with these radionuclides was used to achieve the same spatial and temporal distribution of alpha- and beta-particle dose within the irradiated mice. Some mice were killed to determine the clearance of radiolabeled FAP from their lungs, and the remainder were allocated to a life-span study. All animals were subjected to a detailed necropsy. To facilitate the identification of small tumors, the lungs were rendered transparent in methyl salicylate and examined under back illumination for the presence of lesions. Lung nodules and other microscopic lesions were excised for histological examination. The median survival of mice in all groups was approximately 910 days. The control animals lived longer than those that were irradiated, but it was difficult to determine a dose-response relationship for survival among the exposed mice. Benign adenomas and, less frequently, malignant adenocarcinomas were identified in all animal groups. The prevalence of these tumors was approximately 28.8% in the control mice, which is consistent with the results of other studies using the same strain of mouse. After exposure to radionuclide-labeled FAP, there was a significant dose-related increase in the prevalence of lung tumors in (242)Cm- (peak prevalence 55%) and (45)Ca-exposed (peak prevalence 48.6%) mice. The prevalence of tumors in the mice that received (242)Cm-labeled FAP was approximately twice that in the mice that inhaled (45)Ca-labeled FAP within the range of doses employed (0.55-4.69 Gy). Using the ratio of the slope of the linear component of the dose-response curves, the toxicity of the alpha particles relative to the beta particles was 1

  7. 7 CFR 1948.98 - Grant agreements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 13 2013-01-01 2013-01-01 false Grant agreements. 1948.98 Section 1948.98 Agriculture... § 1948.98 Grant agreements. The following Grant Agreements are a part of this regulation. (a) Exhibit A of this subpart is a Grant Agreement for Growth Management and Housing Planning Grants for...

  8. 7 CFR 1948.98 - Grant agreements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 13 2011-01-01 2009-01-01 true Grant agreements. 1948.98 Section 1948.98 Agriculture... § 1948.98 Grant agreements. The following Grant Agreements are a part of this regulation. (a) Exhibit A of this subpart is a Grant Agreement for Growth Management and Housing Planning Grants for...

  9. 25 CFR 163.71 - Agreement funding.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Agreement funding. 163.71 Section 163.71 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Cooperative Agreements § 163.71 Agreement funding. In cooperative agreements, the Secretary is authorized to advance...

  10. 25 CFR 163.71 - Agreement funding.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Agreement funding. 163.71 Section 163.71 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Cooperative Agreements § 163.71 Agreement funding. In cooperative agreements, the Secretary is authorized to advance...

  11. 25 CFR 163.71 - Agreement funding.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Agreement funding. 163.71 Section 163.71 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Cooperative Agreements § 163.71 Agreement funding. In cooperative agreements, the Secretary is authorized to advance...

  12. 25 CFR 163.71 - Agreement funding.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Agreement funding. 163.71 Section 163.71 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Cooperative Agreements § 163.71 Agreement funding. In cooperative agreements, the Secretary is authorized to advance...

  13. 25 CFR 163.71 - Agreement funding.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Agreement funding. 163.71 Section 163.71 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Cooperative Agreements § 163.71 Agreement funding. In cooperative agreements, the Secretary is authorized to advance...

  14. 78 FR 63474 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-24

    ... under the Shipping Act of 1984. Interested parties may submit comments on the agreements to the....gov . Agreement No.: 012204-001. Title: ELJSA-Hanjin Shipping Slot Exchange Agreement. Parties: Evergreen Line Joint Service Agreement and Hanjin Shipping Co. Ltd. Filing Party: Paul M. Keane,...

  15. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Project agreement. 710.307 Section 710.307 Highways... REAL ESTATE Project Development § 710.307 Project agreement. As a condition of Federal-aid, the STD... project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on...

  16. 46 CFR 356.41 - Management agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Management agreements. 356.41 Section 356.41 Shipping..., Management Agreements and Exclusive or Long-Term Contracts § 356.41 Management agreements. (a) An owner or bareboat charterer of a Fishing Industry Vessel may enter into a management agreement with a Non-Citizen...

  17. 46 CFR 356.41 - Management agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Management agreements. 356.41 Section 356.41 Shipping..., Management Agreements and Exclusive or Long-Term Contracts § 356.41 Management agreements. (a) An owner or bareboat charterer of a Fishing Industry Vessel may enter into a management agreement with a Non-Citizen...

  18. 7 CFR 947.111 - Marketing agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Marketing agreement. 947.111 Section 947.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Definitions § 947.111 Marketing agreement. Marketing agreement means Marketing Agreement No. 114, as amended....

  19. 7 CFR 947.111 - Marketing agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Marketing agreement. 947.111 Section 947.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Definitions § 947.111 Marketing agreement. Marketing agreement means Marketing Agreement No. 114, as amended....

  20. 7 CFR 947.111 - Marketing agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Marketing agreement. 947.111 Section 947.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... Definitions § 947.111 Marketing agreement. Marketing agreement means Marketing Agreement No. 114, as amended....

  1. 7 CFR 947.111 - Marketing agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Marketing agreement. 947.111 Section 947.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Definitions § 947.111 Marketing agreement. Marketing agreement means Marketing Agreement No. 114, as amended....

  2. 7 CFR 947.111 - Marketing agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Marketing agreement. 947.111 Section 947.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... Definitions § 947.111 Marketing agreement. Marketing agreement means Marketing Agreement No. 114, as amended....

  3. 46 CFR 356.41 - Management agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false Management agreements. 356.41 Section 356.41 Shipping..., Management Agreements and Exclusive or Long-Term Contracts § 356.41 Management agreements. (a) An owner or bareboat charterer of a Fishing Industry Vessel may enter into a management agreement with a Non-Citizen...

  4. 46 CFR 356.41 - Management agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 8 2012-10-01 2012-10-01 false Management agreements. 356.41 Section 356.41 Shipping..., Management Agreements and Exclusive or Long-Term Contracts § 356.41 Management agreements. (a) An owner or bareboat charterer of a Fishing Industry Vessel may enter into a management agreement with a Non-Citizen...

  5. 46 CFR 356.41 - Management agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false Management agreements. 356.41 Section 356.41 Shipping..., Management Agreements and Exclusive or Long-Term Contracts § 356.41 Management agreements. (a) An owner or bareboat charterer of a Fishing Industry Vessel may enter into a management agreement with a Non-Citizen...

  6. 40 CFR 46.170 - Fellowship agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Fellowship agreement. 46.170 Section 46... FELLOWSHIPS Award § 46.170 Fellowship agreement. (a) The “Fellowship Agreement” (EPA Form 5770-8) is the written agreement, including amendments, between EPA and you. The fellowship agreement will state...

  7. 40 CFR 46.170 - Fellowship agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Fellowship agreement. 46.170 Section 46... FELLOWSHIPS Award § 46.170 Fellowship agreement. (a) The “Fellowship Agreement” (EPA Form 5770-8) is the written agreement, including amendments, between EPA and you. The fellowship agreement will state...

  8. 40 CFR 46.170 - Fellowship agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Fellowship agreement. 46.170 Section 46... FELLOWSHIPS Award § 46.170 Fellowship agreement. (a) The “Fellowship Agreement” (EPA Form 5770-8) is the written agreement, including amendments, between EPA and you. The fellowship agreement will state...

  9. 40 CFR 46.170 - Fellowship agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Fellowship agreement. 46.170 Section 46... FELLOWSHIPS Award § 46.170 Fellowship agreement. (a) The “Fellowship Agreement” (EPA Form 5770-8) is the written agreement, including amendments, between EPA and you. The fellowship agreement will state...

  10. 40 CFR 46.170 - Fellowship agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Fellowship agreement. 46.170 Section 46... FELLOWSHIPS Award § 46.170 Fellowship agreement. (a) The “Fellowship Agreement” (EPA Form 5770-8) is the written agreement, including amendments, between EPA and you. The fellowship agreement will state...

  11. 45 CFR 1155.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Cooperative agreement. 1155.620 Section 1155.620... ASSISTANCE) Definitions § 1155.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  12. 22 CFR 312.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Cooperative agreement. 312.620 Section 312.620...) Definitions § 312.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  13. 22 CFR 1008.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Cooperative agreement. 1008.620 Section 1008.620... ASSISTANCE) Definitions § 1008.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  14. 36 CFR 1212.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false Cooperative agreement. 1212... § 1212.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  15. 36 CFR 1212.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Cooperative agreement. 1212... § 1212.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  16. 22 CFR 133.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Cooperative agreement. 133.620 Section 133.620... (FINANCIAL ASSISTANCE) Definitions § 133.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  17. 2 CFR 1401.220 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Cooperative agreement. 1401.220 Section 1401... INTERIOR REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1401.220 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  18. 34 CFR 84.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 1 2014-07-01 2014-07-01 false Cooperative agreement. 84.620 Section 84.620 Education... (FINANCIAL ASSISTANCE) Definitions § 84.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C....

  19. 45 CFR 1155.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Cooperative agreement. 1155.620 Section 1155.620... ASSISTANCE) Definitions § 1155.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  20. 34 CFR 84.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 1 2012-07-01 2012-07-01 false Cooperative agreement. 84.620 Section 84.620 Education... (FINANCIAL ASSISTANCE) Definitions § 84.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C....

  1. 22 CFR 312.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Cooperative agreement. 312.620 Section 312.620...) Definitions § 312.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  2. 22 CFR 1509.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Cooperative agreement. 1509.620 Section 1509.620... (FINANCIAL ASSISTANCE) Definitions § 1509.620 Cooperative agreement. Cooperative agreement means an award of... award. The term does not include cooperative research and development agreements as defined in 15...

  3. 20 CFR 439.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Cooperative agreement. 439.620 Section 439... WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 439.620 Cooperative agreement. Cooperative agreement means an... contemplated by the award. The term does not include cooperative research and development agreements as...

  4. 2 CFR 200.24 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Cooperative agreement. 200.24 Section 200.24... REQUIREMENTS FOR FEDERAL AWARDS Acronyms and Definitions Acronyms § 200.24 Cooperative agreement. Cooperative... include: (1) A cooperative research and development agreement as defined in 15 U.S.C. 3710a; or (2)...

  5. 22 CFR 1008.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Cooperative agreement. 1008.620 Section 1008.620... ASSISTANCE) Definitions § 1008.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  6. 26 CFR 601.802 - Cooperative agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 20 2011-04-01 2011-04-01 false Cooperative agreements. 601.802 Section 601.802... STATEMENT OF PROCEDURAL RULES Tax Counseling for the Elderly § 601.802 Cooperative agreements. (a) General... cooperative agreements with the Internal Revenue Service. Use of cooperative agreements is in accordance...

  7. 22 CFR 1008.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Cooperative agreement. 1008.620 Section 1008.620... ASSISTANCE) Definitions § 1008.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  8. 45 CFR 1155.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Cooperative agreement. 1155.620 Section 1155.620... ASSISTANCE) Definitions § 1155.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  9. 49 CFR 32.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 1 2012-10-01 2012-10-01 false Cooperative agreement. 32.620 Section 32.620... (FINANCIAL ASSISTANCE) Definitions § 32.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  10. 29 CFR 94.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Cooperative agreement. 94.620 Section 94.620 Labor Office...) Definitions § 94.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  11. 45 CFR 1173.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Cooperative agreement. 1173.620 Section 1173.620... (FINANCIAL ASSISTANCE) Definitions § 1173.620 Cooperative agreement. Cooperative agreement means an award of... award. The term does not include cooperative research and development agreements as defined in 15...

  12. 2 CFR 182.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Cooperative agreement. 182.620 Section 182... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 182.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  13. 21 CFR 1405.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Cooperative agreement. 1405.620 Section 1405.620... WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1405.620 Cooperative agreement. Cooperative agreement means... contemplated by the award. The term does not include cooperative research and development agreements as...

  14. 2 CFR 182.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Cooperative agreement. 182.620 Section 182... FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 182.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C. 6305, is used...

  15. 26 CFR 601.802 - Cooperative agreements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 20 2012-04-01 2012-04-01 false Cooperative agreements. 601.802 Section 601.802... STATEMENT OF PROCEDURAL RULES Tax Counseling for the Elderly § 601.802 Cooperative agreements. (a) General... cooperative agreements with the Internal Revenue Service. Use of cooperative agreements is in accordance...

  16. 49 CFR 32.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Cooperative agreement. 32.620 Section 32.620... (FINANCIAL ASSISTANCE) Definitions § 32.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  17. 22 CFR 312.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Cooperative agreement. 312.620 Section 312.620...) Definitions § 312.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  18. 36 CFR 1212.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false Cooperative agreement. 1212... § 1212.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  19. 45 CFR 1155.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Cooperative agreement. 1155.620 Section 1155.620... ASSISTANCE) Definitions § 1155.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  20. 21 CFR 1405.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Cooperative agreement. 1405.620 Section 1405.620... WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1405.620 Cooperative agreement. Cooperative agreement means... contemplated by the award. The term does not include cooperative research and development agreements as...

  1. 28 CFR 83.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Cooperative agreement. 83.620 Section 83...-FREE WORKPLACE (GRANTS) Definitions § 83.620 Cooperative agreement. Cooperative agreement means an... by the award. The term does not include cooperative research and development agreements as defined...

  2. 29 CFR 94.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 1 2013-07-01 2013-07-01 false Cooperative agreement. 94.620 Section 94.620 Labor Office...) Definitions § 94.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  3. 22 CFR 133.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Cooperative agreement. 133.620 Section 133.620... (FINANCIAL ASSISTANCE) Definitions § 133.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  4. 45 CFR 1155.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Cooperative agreement. 1155.620 Section 1155.620... ASSISTANCE) Definitions § 1155.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  5. 36 CFR 1212.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true Cooperative agreement. 1212... § 1212.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  6. 21 CFR 1405.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Cooperative agreement. 1405.620 Section 1405.620... WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1405.620 Cooperative agreement. Cooperative agreement means... contemplated by the award. The term does not include cooperative research and development agreements as...

  7. 22 CFR 210.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Cooperative agreement. 210.620 Section 210.620... (FINANCIAL ASSISTANCE) Definitions § 210.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  8. 28 CFR 83.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Cooperative agreement. 83.620 Section 83...-FREE WORKPLACE (GRANTS) Definitions § 83.620 Cooperative agreement. Cooperative agreement means an... by the award. The term does not include cooperative research and development agreements as defined...

  9. 49 CFR 32.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false Cooperative agreement. 32.620 Section 32.620... (FINANCIAL ASSISTANCE) Definitions § 32.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  10. 7 CFR 1491.20 - Cooperative agreements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Cooperative agreements. 1491.20 Section 1491.20... Cooperative Agreements and Conservation Easement Deeds § 1491.20 Cooperative agreements. (a) NRCS, on behalf of CCC, shall enter into a cooperative agreement with those entities selected for funding. Once...

  11. 22 CFR 133.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Cooperative agreement. 133.620 Section 133.620... (FINANCIAL ASSISTANCE) Definitions § 133.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  12. 28 CFR 83.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Cooperative agreement. 83.620 Section 83...-FREE WORKPLACE (GRANTS) Definitions § 83.620 Cooperative agreement. Cooperative agreement means an... by the award. The term does not include cooperative research and development agreements as defined...

  13. 2 CFR 182.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Cooperative agreement. 182.620 Section 182... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 182.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  14. 22 CFR 312.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Cooperative agreement. 312.620 Section 312.620...) Definitions § 312.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  15. 22 CFR 1509.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Cooperative agreement. 1509.620 Section 1509.620... (FINANCIAL ASSISTANCE) Definitions § 1509.620 Cooperative agreement. Cooperative agreement means an award of... award. The term does not include cooperative research and development agreements as defined in 15...

  16. 22 CFR 133.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Cooperative agreement. 133.620 Section 133.620... (FINANCIAL ASSISTANCE) Definitions § 133.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  17. 26 CFR 601.802 - Cooperative agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 20 2014-04-01 2014-04-01 false Cooperative agreements. 601.802 Section 601.802... STATEMENT OF PROCEDURAL RULES Tax Counseling for the Elderly § 601.802 Cooperative agreements. (a) General... cooperative agreements with the Internal Revenue Service. Use of cooperative agreements is in accordance...

  18. 7 CFR 3021.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 15 2011-01-01 2011-01-01 false Cooperative agreement. 3021.620 Section 3021.620...) Definitions § 3021.620 Cooperative agreement. Cooperative agreement means an award of financial assistance... not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  19. 49 CFR 32.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false Cooperative agreement. 32.620 Section 32.620... (FINANCIAL ASSISTANCE) Definitions § 32.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  20. 36 CFR 1212.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Cooperative agreement. 1212... § 1212.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  1. 29 CFR 94.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Cooperative agreement. 94.620 Section 94.620 Labor Office of...) Definitions § 94.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  2. 2 CFR 1401.220 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Cooperative agreement. 1401.220 Section 1401... INTERIOR REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1401.220 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  3. 49 CFR 32.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 1 2014-10-01 2014-10-01 false Cooperative agreement. 32.620 Section 32.620... (FINANCIAL ASSISTANCE) Definitions § 32.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  4. 21 CFR 1405.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Cooperative agreement. 1405.620 Section 1405.620... WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1405.620 Cooperative agreement. Cooperative agreement means... contemplated by the award. The term does not include cooperative research and development agreements as...

  5. 22 CFR 1509.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Cooperative agreement. 1509.620 Section 1509.620... (FINANCIAL ASSISTANCE) Definitions § 1509.620 Cooperative agreement. Cooperative agreement means an award of... award. The term does not include cooperative research and development agreements as defined in 15...

  6. 22 CFR 312.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Cooperative agreement. 312.620 Section 312.620...) Definitions § 312.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  7. 28 CFR 83.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Cooperative agreement. 83.620 Section 83...-FREE WORKPLACE (GRANTS) Definitions § 83.620 Cooperative agreement. Cooperative agreement means an... by the award. The term does not include cooperative research and development agreements as defined...

  8. 22 CFR 133.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Cooperative agreement. 133.620 Section 133.620... (FINANCIAL ASSISTANCE) Definitions § 133.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  9. 28 CFR 83.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Cooperative agreement. 83.620 Section 83...-FREE WORKPLACE (GRANTS) Definitions § 83.620 Cooperative agreement. Cooperative agreement means an... by the award. The term does not include cooperative research and development agreements as defined...

  10. 34 CFR 84.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 1 2013-07-01 2013-07-01 false Cooperative agreement. 84.620 Section 84.620 Education... (FINANCIAL ASSISTANCE) Definitions § 84.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C....

  11. 29 CFR 94.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Cooperative agreement. 94.620 Section 94.620 Labor Office of...) Definitions § 94.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  12. 22 CFR 210.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Cooperative agreement. 210.620 Section 210.620... (FINANCIAL ASSISTANCE) Definitions § 210.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  13. 22 CFR 1509.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Cooperative agreement. 1509.620 Section 1509.620... (FINANCIAL ASSISTANCE) Definitions § 1509.620 Cooperative agreement. Cooperative agreement means an award of... award. The term does not include cooperative research and development agreements as defined in 15...

  14. 29 CFR 94.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 1 2012-07-01 2012-07-01 false Cooperative agreement. 94.620 Section 94.620 Labor Office...) Definitions § 94.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  15. 22 CFR 1008.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Cooperative agreement. 1008.620 Section 1008.620... ASSISTANCE) Definitions § 1008.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  16. 34 CFR 84.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Cooperative agreement. 84.620 Section 84.620 Education... (FINANCIAL ASSISTANCE) Definitions § 84.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C....

  17. 34 CFR 84.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 1 2011-07-01 2011-07-01 false Cooperative agreement. 84.620 Section 84.620 Education... (FINANCIAL ASSISTANCE) Definitions § 84.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C....

  18. 2 CFR 1401.220 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Cooperative agreement. 1401.220 Section 1401... INTERIOR REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1401.220 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  19. 7 CFR 3021.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Cooperative agreement. 3021.620 Section 3021.620...) Definitions § 3021.620 Cooperative agreement. Cooperative agreement means an award of financial assistance... not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  20. 7 CFR 3021.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false Cooperative agreement. 3021.620 Section 3021.620...) Definitions § 3021.620 Cooperative agreement. Cooperative agreement means an award of financial assistance... not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  1. 22 CFR 1008.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Cooperative agreement. 1008.620 Section 1008... (FINANCIAL ASSISTANCE) Definitions § 1008.620 Cooperative agreement. Cooperative agreement means an award of... award. The term does not include cooperative research and development agreements as defined in 15...

  2. 22 CFR 1509.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Cooperative agreement. 1509.620 Section 1509... WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1509.620 Cooperative agreement. Cooperative agreement means... contemplated by the award. The term does not include cooperative research and development agreements as...

  3. 21 CFR 1405.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Cooperative agreement. 1405.620 Section 1405.620... WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1405.620 Cooperative agreement. Cooperative agreement means... contemplated by the award. The term does not include cooperative research and development agreements as...

  4. 5 CFR 2421.20 - Election agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Election agreement. 2421.20 Section 2421... Election agreement. Election agreement means an agreement under part 2422 of this subchapter signed by all... representation election in an appropriate unit....

  5. 76 FR 16420 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-23

    ....gov . Agreement No.: 011790-001. Title: Dole Ocean Cargo Express/King Ocean Services Limited Space Charter Agreement. Parties: Dole Ocean Cargo Express, Inc., and King Ocean Services Limited. Filing Party... of King Ocean, and restate the Agreement. Agreement No.: 012088-001. Title: Hanjin and...

  6. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Project agreement. 710.307 Section 710.307 Highways... REAL ESTATE Project Development § 710.307 Project agreement. As a condition of Federal-aid, the STD... project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on...

  7. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Project agreement. 710.307 Section 710.307 Highways... REAL ESTATE Project Development § 710.307 Project agreement. As a condition of Federal-aid, the STD... project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on...

  8. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Project agreement. 710.307 Section 710.307 Highways... REAL ESTATE Project Development § 710.307 Project agreement. As a condition of Federal-aid, the STD... project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on...

  9. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Project agreement. 710.307 Section 710.307 Highways... REAL ESTATE Project Development § 710.307 Project agreement. As a condition of Federal-aid, the STD... project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on...

  10. 75 FR 19402 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-14

    .... Agreement No.: 012042-002. Title: MOL/ELJSA Slot Exchange Agreement. Parties: Evergreen Line Joint Service.... Title: MOL/APL/HMM Asia/USWC Slot Charter Agreement. Parties: American President Lines, Ltd.; APL Co... sold, and updates party addresses. Agreement No.: 012044-003. Title: MOL/CMA CGM Slot Charter...

  11. 7 CFR 1948.98 - Grant agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 13 2012-01-01 2012-01-01 false Grant agreements. 1948.98 Section 1948.98 Agriculture... § 1948.98 Grant agreements. The following Grant Agreements are a part of this regulation. (a) Exhibit A of this subpart is a Grant Agreement for Growth Management and Housing Planning Grants for...

  12. The repeatability of vegetation classification and mapping.

    PubMed

    Hearn, S M; Healey, J R; McDonald, M A; Turner, A J; Wong, J L G; Stewart, G B

    2011-04-01

    The mapping of habitats as defined by plant communities is a common component of the planning and monitoring of conservation management. However, there are major concerns about the subjectivity and risk of observer bias in most commonly used plant community mapping protocols. This study provides the first test of the consistency of habitat maps based on the mapping units defined by the National Vegetation Classification (NVC), the most widely used classification of plant communities used for habitat mapping on conservation sites in the UK. Seven surveyors mapped the same upland site within five weeks in summer 2008 and the spatial correspondence of the resulting maps was assessed. The NVC is a hierarchical classification and pair-wise spatial agreement between maps decreased with lower levels of sub-classification. The average area of agreement between maps was 77.6% at the habitat level, 34.2% at the community level and 18.5% at the sub-community level. Spatial disparity in the location of mapped boundaries between vegetation types only made a small contribution to overall differences; the majority of variation between maps was due to discrepancies in classification, with vegetation types containing similar species composition most often confused. Factors relating to surveyor effort (cost, time taken and length of route) were not able to explain the substantial differences between maps. However, the methods used to assign areas to vegetation type did seem to have an effect, with surveyors who relied primarily on their own experience having the highest levels of mean agreement with other maps. The study raises serious concerns with current practice of using the NVC for site description and monitoring/surveillance. Since this is just a single case study, we recommend that further work is carried out with the aim of determining the degree and source of variation between surveyors and how consistency can be increased.

  13. New classification system for long-bone fractures supplementing the AO/OTA classification.

    PubMed

    Garnavos, Christos; Kanakaris, Nikolaos K; Lasanianos, Nikolaos G; Tzortzi, Paraskevi; West, Robert M

    2012-05-01

    This article describes a novel, clinically oriented classification system for long-bone fractures that is simple, reliable, and useful to predict treatment method, complications, and outcome. The reliability and memorability of the new classification were statistically tested and compared with the AO-Müller/Orthopaedic Trauma Association (AO/OTA) long-bone fracture classification. The proposed classification system was also clinically validated with a targeted pilot study designed for content and clinical outcome retrospectively reviewing 122 closed tibial shaft fractures, which were used as a representative paradigm of long-bone fractures. Statistical evaluation showed that the proposed classification system had improved inter- and intraobserver variation agreement and easier memorability compared with the AO/OTA classification system. The clinical validation study showed its predictive value regarding selection of treatment method, complication rate, and injury outcome.The proposed classification system proved simple, reliable, and memorable. Its clinical value appeared strong enough to justify the organization of larger studies for a complete assessment of its clinical usefulness for all long-bone fractures.

  14. Unsupervised classification of remote multispectral sensing data

    NASA Technical Reports Server (NTRS)

    Su, M. Y.

    1972-01-01

    The new unsupervised classification technique for classifying multispectral remote sensing data which can be either from the multispectral scanner or digitized color-separation aerial photographs consists of two parts: (a) a sequential statistical clustering which is a one-pass sequential variance analysis and (b) a generalized K-means clustering. In this composite clustering technique, the output of (a) is a set of initial clusters which are input to (b) for further improvement by an iterative scheme. Applications of the technique using an IBM-7094 computer on multispectral data sets over Purdue's Flight Line C-1 and the Yellowstone National Park test site have been accomplished. Comparisons between the classification maps by the unsupervised technique and the supervised maximum liklihood technique indicate that the classification accuracies are in agreement.

  15. The oil and gas joint operating agreement

    SciTech Connect

    Not Available

    1990-01-01

    This book covers the following topics: introduction to the AAPL model form operating agreement; property provisions of the operating agreement; Article 6---the drilling and development article; duties and obligations revisited---who bear what risk of loss; operator's liens; accounting procedure joint operations; insurance; taking gas in kind absent a balancing agreement; RMMLF Form 5 Gas Balancing Agreement; tax partnerships for nontax professionals; alternative agreement forms.

  16. Security classification of information

    SciTech Connect

    Quist, A.S.

    1993-04-01

    This document is the second of a planned four-volume work that comprehensively discusses the security classification of information. The main focus of Volume 2 is on the principles for classification of information. Included herein are descriptions of the two major types of information that governments classify for national security reasons (subjective and objective information), guidance to use when determining whether information under consideration for classification is controlled by the government (a necessary requirement for classification to be effective), information disclosure risks and benefits (the benefits and costs of classification), standards to use when balancing information disclosure risks and benefits, guidance for assigning classification levels (Top Secret, Secret, or Confidential) to classified information, guidance for determining how long information should be classified (classification duration), classification of associations of information, classification of compilations of information, and principles for declassifying and downgrading information. Rules or principles of certain areas of our legal system (e.g., trade secret law) are sometimes mentioned to .provide added support to some of those classification principles.

  17. Recursive heuristic classification

    NASA Technical Reports Server (NTRS)

    Wilkins, David C.

    1994-01-01

    The author will describe a new problem-solving approach called recursive heuristic classification, whereby a subproblem of heuristic classification is itself formulated and solved by heuristic classification. This allows the construction of more knowledge-intensive classification programs in a way that yields a clean organization. Further, standard knowledge acquisition and learning techniques for heuristic classification can be used to create, refine, and maintain the knowledge base associated with the recursively called classification expert system. The method of recursive heuristic classification was used in the Minerva blackboard shell for heuristic classification. Minerva recursively calls itself every problem-solving cycle to solve the important blackboard scheduler task, which involves assigning a desirability rating to alternative problem-solving actions. Knowing these ratings is critical to the use of an expert system as a component of a critiquing or apprenticeship tutoring system. One innovation of this research is a method called dynamic heuristic classification, which allows selection among dynamically generated classification categories instead of requiring them to be prenumerated.

  18. The clinical utility of pain classification in non-specific arm pain.

    PubMed

    Moloney, Niamh A; Hall, Toby M; Leaver, Andrew M; Doody, Catherine M

    2015-02-01

    Mechanisms-based pain classification has received considerable attention recently for its potential use in clinical decision making. A number of algorithms for pain classification have been proposed. Non-specific arm pain (NSAP) is a poorly defined condition, which could benefit from classification according to pain mechanisms to improve treatment selection. This study used three published classification algorithms (hereafter called NeuPSIG, Smart, Schafer) to investigate the frequency of different pain classifications in NSAP and the clinical utility of these systems in assessing NSAP. Forty people with NSAP underwent a clinical examination and quantitative sensory testing. Findings were used to classify participants according to three classification algorithms. Frequency of pain classification including number unclassified was analysed using descriptive statistics. Inter-rater agreement was analysed using kappa coefficients. NSAP was primarily classified as 'unlikely neuropathic pain' using NeuPSIG criteria, 'peripheral neuropathic pain' using the Smart classification and 'peripheral nerve sensitisation' using the Schafer algorithm. Two of the three algorithms allowed classification of all but one participant; up to 45% of participants (n = 18) were categorised as mixed by the Smart classification. Inter-rater agreement was good for the Schafer algorithm (к = 0.78) and moderate for the Smart classification (к = 0.40). A kappa value was unattainable for the NeuPSIG algorithm but agreement was high. Pain classification was achievable with high inter-rater agreement for two of the three algorithms assessed. The Smart classification may be useful but requires further direction regarding the use of clinical criteria included. The impact of adding a pain classification to clinical assessment on patient outcomes needs to be evaluated.

  19. Classification of Stellar Spectra

    NASA Astrophysics Data System (ADS)

    Garrison, R.; Murdin, P.

    2000-11-01

    How does a scientist approach the problem of trying to understand countless billions of objects? One of the first steps is to organize the data and set up a classification scheme which can provide the best insights into the nature of the objects. Perception and insight are the main purposes of classification. In astronomy, where there are `billions and billions' of stars, classification is an ong...

  20. Classiology and soil classification

    NASA Astrophysics Data System (ADS)

    Rozhkov, V. A.

    2012-03-01

    Classiology can be defined as a science studying the principles and rules of classification of objects of any nature. The development of the theory of classification and the particular methods for classifying objects are the main challenges of classiology; to a certain extent, they are close to the challenges of pattern recognition. The methodology of classiology integrates a wide range of methods and approaches: from expert judgment to formal logic, multivariate statistics, and informatics. Soil classification assumes generalization of available data and practical experience, formalization of our notions about soils, and their representation in the form of an information system. As an information system, soil classification is designed to predict the maximum number of a soil's properties from the position of this soil in the classification space. The existing soil classification systems do not completely satisfy the principles of classiology. The violation of logical basis, poor structuring, low integrity, and inadequate level of formalization make these systems verbal schemes rather than classification systems sensu stricto. The concept of classification as listing (enumeration) of objects makes it possible to introduce the notion of the information base of classification. For soil objects, this is the database of soil indices (properties) that might be applied for generating target-oriented soil classification system. Mathematical methods enlarge the prognostic capacity of classification systems; they can be applied to assess the quality of these systems and to recognize new soil objects to be included in the existing systems. The application of particular principles and rules of classiology for soil classification purposes is discussed in this paper.

  1. 77 FR 60730 - Product Change-Express Mail and Priority Mail Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-04

    ... Change--Express Mail and Priority Mail Negotiated Service Agreement AGENCY: Postal Service\\TM\\. ACTION... Mail Classification Schedule's Competitive Products List. DATES: Effective date: October 4, 2012. FOR... Express Mail & Priority Mail Contract 10 to Competitive Product List. Documents are available at...

  2. 77 FR 64150 - Product Change-Express Mail and Priority Mail Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-18

    ... Change--Express Mail and Priority Mail Negotiated Service Agreement AGENCY: Postal Service\\TM\\. ACTION... Mail Classification Schedule's Competitive Products List. DATES: Effective date: October 18, 2012. FOR... Express Mail & Priority Mail Contract 11 to Competitive Product List. Documents are available at...

  3. 77 FR 38684 - Product Change-Express Mail & Priority Mail Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-28

    ... Change--Express Mail & Priority Mail Negotiated Service Agreement AGENCY: Postal Service. TM ACTION... Mail Classification Schedule's Competitive Products List. DATES: June 28, 2012. FOR FURTHER INFORMATION... Postal Regulatory Commission a Request of the United States Postal Service to Add Express Mail &...

  4. 78 FR 6361 - Product Change-Express Mail and Priority Mail Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-30

    ... Change--Express Mail and Priority Mail Negotiated Service Agreement AGENCY: Postal Service TM . ACTION... Mail Classification Schedule's Competitive Products List. DATES: Effective date: January 30, 2013. FOR... Express Mail & Priority Mail Contract 13 to Competitive Product List. Documents are available at...

  5. 22 CFR 41.59 - Professionals under the North American Free Trade Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Professionals under the North American Free Trade Agreement. (a) Requirements for classification as a NAFTA... NAFTA Professional to the alien or official confirmation of such petition approval, or DHS confirmation... United States requiring employment of a person in a professional capacity consistent with NAFTA...

  6. 22 CFR 41.59 - Professionals under the North American Free Trade Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Professionals under the North American Free Trade Agreement. (a) Requirements for classification as a NAFTA... NAFTA Professional to the alien or official confirmation of such petition approval, or DHS confirmation... United States requiring employment of a person in a professional capacity consistent with NAFTA...

  7. 22 CFR 41.59 - Professionals under the North American Free Trade Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Professionals under the North American Free Trade Agreement. (a) Requirements for classification as a NAFTA... NAFTA Professional to the alien or official confirmation of such petition approval, or DHS confirmation... United States requiring employment of a person in a professional capacity consistent with NAFTA...

  8. 22 CFR 41.59 - Professionals under the North American Free Trade Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Professionals under the North American Free Trade Agreement. (a) Requirements for classification as a NAFTA... NAFTA Professional to the alien or official confirmation of such petition approval, or DHS confirmation... United States requiring employment of a person in a professional capacity consistent with NAFTA...

  9. Proteomic Profiling of Hematopoietic Stem/Progenitor Cells after a Whole Body Exposure of CBA/CaJ Mice to Titanium ((48)Ti) Ions.

    PubMed

    Rithidech, Kanokporn Noy; Tungjai, Montree; Jangiam, Witawat; Honikel, Louise; Gordon, Chris; Lai, Xianyin; Witzmann, Frank

    2015-07-21

    Myeloid leukemia (ML) is one of the major health concerns from exposure to radiation. However, the risk assessment for developing ML after exposure to space radiation remains uncertain. To reduce the uncertainty in risk prediction for ML, a much increased understanding of space radiation-induced changes in the target cells, i.e., hematopoietic stem/progenitor cells (HSPCs), is critically important. We used the label-free quantitative mass spectrometry (LFQMS) proteomic approach to determine the expression of protein in HSPC-derived myeloid colonies obtained at an early time-point (one week) and a late time-point (six months) after an acute whole body exposure of CBA/CaJ mice to a total dose of 0, 0.1, 0.25, or 0.5 Gy of heavy-ion titanium ((48)Ti ions), which are the important component of radiation found in the space environment. Mice exposed to 0 Gy of (48)Ti ions served as non-irradiated sham controls. There were five mice per treatment groups at each harvest time. The Trans-Proteomic Pipeline (TPP) was used to assign a probability of a particular protein being in the sample. A proof-of-concept based Ingenuity Pathway Analysis (IPA) was used to characterize the functions, pathways, and networks of the identified proteins. Alterations of expression levels of proteins detected in samples collected at one week (wk) post-irradiation reflects acute effects of exposure to (48)Ti ions, while those detected in samples collected at six months (mos) post-irradiation represent protein expression profiles involved in the induction of late-occurring damage (normally referred to as genomic instability). Our results obtained by using the IPA analyses indicate a wide array of signaling pathways involved in response to 1 GeV/n (48)Ti ions at both harvest times. Our data also demonstrate that the patterns of protein expression profiles are dose and time dependent. The majority of proteins with altered expression levels are involved in cell cycle control, cellular growth and

  10. Proteomic Profiling of Hematopoietic Stem/Progenitor Cells after a Whole Body Exposure of CBA/CaJ Mice to Titanium (48Ti) Ions

    PubMed Central

    Rithidech, Kanokporn Noy; Tungjai, Montree; Jangiam, Witawat; Honikel, Louise; Gordon, Chris; Lai, Xianyin; Witzmann, Frank

    2015-01-01

    Myeloid leukemia (ML) is one of the major health concerns from exposure to radiation. However, the risk assessment for developing ML after exposure to space radiation remains uncertain. To reduce the uncertainty in risk prediction for ML, a much increased understanding of space radiation-induced changes in the target cells, i.e., hematopoietic stem/progenitor cells (HSPCs), is critically important. We used the label-free quantitative mass spectrometry (LFQMS) proteomic approach to determine the expression of protein in HSPC-derived myeloid colonies obtained at an early time-point (one week) and a late time-point (six months) after an acute whole body exposure of CBA/CaJ mice to a total dose of 0, 0.1, 0.25, or 0.5 Gy of heavy-ion titanium (48Ti ions), which are the important component of radiation found in the space environment. Mice exposed to 0 Gy of 48Ti ions served as non-irradiated sham controls. There were five mice per treatment groups at each harvest time. The Trans-Proteomic Pipeline (TPP) was used to assign a probability of a particular protein being in the sample. A proof-of-concept based Ingenuity Pathway Analysis (IPA) was used to characterize the functions, pathways, and networks of the identified proteins. Alterations of expression levels of proteins detected in samples collected at one week (wk) post-irradiation reflects acute effects of exposure to 48Ti ions, while those detected in samples collected at six months (mos) post-irradiation represent protein expression profiles involved in the induction of late-occurring damage (normally referred to as genomic instability). Our results obtained by using the IPA analyses indicate a wide array of signaling pathways involved in response to 1 GeV/n 48Ti ions at both harvest times. Our data also demonstrate that the patterns of protein expression profiles are dose and time dependent. The majority of proteins with altered expression levels are involved in cell cycle control, cellular growth and proliferation

  11. Sexual Agreements among Gay Male Couples

    PubMed Central

    Hoff, Colleen H.; Beougher, Sean C.

    2009-01-01

    Many gay male couples make agreements about whether or not to permit sex with outside partners, yet little is known about the development and maintenance of these agreements, their impact on relationships, and whether they are an effective HIV prevention strategy. Using semi-structured, qualitative interviews, 39 gay male couples were asked about their sexual agreements and about other relationship dynamics that might affect their agreements. Analysis revealed a wide range of agreement types, all of which are presented along a continuum rather than as discrete categories. For couples with open agreements, most placed rules or conditions limiting when, where, how often, and with whom outside sex was permitted. Although motivations for having agreements varied, HIV prevention did not rank as a primary factor for any couple. Most couples had congruous agreements; however, a small number reported discrepancies which may increase HIV transmission risk. How couples handled breaks in their agreements also varied, depending on what condition was broken, whether it was disclosed, and the partner's reaction. Additional results include differences in agreement type and motivations for having an agreement based on couple serostatus. Overall, agreements benefited couples by providing boundaries for the relationship, supporting a non-heteronormative identity, and fulfilling the sexual needs of the couple. Future prevention efforts involving gay couples must address the range of agreement types and the meanings couples ascribe to them, in addition to tempering safety messages with the relationship issues that are important to and faced by gay couples. PMID:18686027

  12. 22 CFR 124.1 - Manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Manufacturing license agreements and technical... ARMS REGULATIONS AGREEMENTS, OFF-SHORE PROCUREMENT AND OTHER DEFENSE SERVICES § 124.1 Manufacturing... manufacturing license agreements, technical assistance agreements, distribution agreements, or...

  13. 22 CFR 124.1 - Manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Manufacturing license agreements and technical... ARMS REGULATIONS AGREEMENTS, OFF-SHORE PROCUREMENT AND OTHER DEFENSE SERVICES § 124.1 Manufacturing... manufacturing license agreements, technical assistance agreements, distribution agreements, or...

  14. 22 CFR 124.1 - Manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Manufacturing license agreements and technical... ARMS REGULATIONS AGREEMENTS, OFF-SHORE PROCUREMENT, AND OTHER DEFENSE SERVICES § 124.1 Manufacturing... manufacturing license agreements, technical assistance agreements, distribution agreements, or...

  15. 22 CFR 124.1 - Manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Manufacturing license agreements and technical... ARMS REGULATIONS AGREEMENTS, OFF-SHORE PROCUREMENT AND OTHER DEFENSE SERVICES § 124.1 Manufacturing... manufacturing license agreements, technical assistance agreements, distribution agreements, or...

  16. 22 CFR 124.1 - Manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Manufacturing license agreements and technical... ARMS REGULATIONS AGREEMENTS, OFF-SHORE PROCUREMENT AND OTHER DEFENSE SERVICES § 124.1 Manufacturing... manufacturing license agreements, technical assistance agreements, distribution agreements, or...

  17. Automated feature extraction and classification from image sources

    USGS Publications Warehouse

    ,

    1995-01-01

    The U.S. Department of the Interior, U.S. Geological Survey (USGS), and Unisys Corporation have completed a cooperative research and development agreement (CRADA) to explore automated feature extraction and classification from image sources. The CRADA helped the USGS define the spectral and spatial resolution characteristics of airborne and satellite imaging sensors necessary to meet base cartographic and land use and land cover feature classification requirements and help develop future automated geographic and cartographic data production capabilities. The USGS is seeking a new commercial partner to continue automated feature extraction and classification research and development.

  18. 78 FR 44563 - Notice of Agreement Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-24

    ....: 012213. Title: Simatech/ELJSA Slot Purchase Agreement. Parties: Simatech Americas S.A. and Evergreen Line..., LLP; 61 Broadway, Suite 3000, New York, NY 10006- 2802. Synopsis: The agreement authorizes...

  19. 75 FR 61757 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-06

    ....: 012071-001. Title: APL/Hanjin Reciprocal Space Charter Agreement. Parties: American President Lines, Ltd... Agreement. Parties: Eagle Marine Services, Ltd.; Ports of America Outer Harbor Terminal, LLC; Port...

  20. 37 CFR 42.409 - Settlement agreements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... OF COMMERCE TRIAL PRACTICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Derivation After Institution of Derivation Proceeding § 42.409 Settlement agreements. An agreement or understanding under 35 U.S.C. 135(e)...

  1. 76 FR 72408 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-23

    ....S. East coast. Agreement No.: 012146. Title: HLAG/HSDG USWC-Mediterranean Vessel Sharing Agreement..., Morocco, Panama, Colombia, the Dominican Republic, Canada, and Mexico. By Order of the Federal...

  2. 48 CFR 1542.1203 - Processing agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MANAGEMENT CONTRACT ADMINISTRATION Novation and Change of Name Agreements 1542.1203 Processing agreements. (a... covering all applicable outstanding and incomplete contracts affected by the transfer of assets or...

  3. 48 CFR 1542.1203 - Processing agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CONTRACT MANAGEMENT CONTRACT ADMINISTRATION Novation and Change of Name Agreements 1542.1203 Processing... assets or change of name. A supplemental agreement number need not be obtained for contracts other...

  4. 78 FR 68444 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-14

    ... . Agreement No.: 010071-040. Title: Cruise Lines International Association Agreement. Parties: AMA Waterways; American Cruise Lines, Inc.; Avalon Waterways; Azamara Cruises; Carnival Cruise Lines; Celebrity Cruises, Inc.; Costa Cruise Lines; Crystal Cruises; Cunard Line; Disney Cruise Line; Holland America...

  5. 75 FR 2141 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-14

    ....gov . Agreement No.: 010071-037. ] Title: Cruise Lines International Association Agreement. Parties: AMA Waterways; American Cruise Lines, Inc.; Azamara Cruises; Carnival Cruise Lines; Celebrity Cruises, Inc.; Costa Cruise Lines; Crystal Cruises; Cunard Line; Disney Cruise Line; Holland America...

  6. 32 CFR 37.1260 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Definitions of Terms Used in This Part § 37.1260 Cooperative... the cooperative agreement. The term does not include “cooperative research and development...

  7. 77 FR 33459 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-06

    ... Agreement and to share the cost of same. Agreement No.: 012173. Title: Hyundai/MOL/APL Asia/Latin America/U... authorizes Hyundai to charter space to MOL and APL in the relevant trade and to authorize the parties...

  8. 75 FR 8719 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ....gov . Agreement No.: 011346-020. Title: Israel Trade Conference Agreement. Parties: American President.... Filing Party: Howard A. Levy, Esq.; Chairman; Israel Trade Conference; 80 Wall Street, Suite 1117;...

  9. 75 FR 6397 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-09

    ....gov . Agreement No.: 011346-019. Title: Israel Trade Conference Agreement. Parties: A.P. Moller-Maersk..., Esq.; Chairman; Israel Trade Conference; 80 Wall Street, Suite 1117; New York, NY 10005-3602....

  10. 76 FR 63618 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... Singapore. Agreement No.: 012138. Title: CSAV/CCNI Venezuela Space Charter Agreement. Parties: Compana Sud... Venezuela. Dated: October 7, 2011. By Order of the Federal Maritime Commission. Karen V. Gregory,...

  11. Multilayer Perceptrons for Classification

    DTIC Science & Technology

    1992-03-01

    retention/ separation rates fu, input to force projection models. The second application concerns the classification of Armor Piercing Incendiary (API...Air Force pilot reten- tion/ separation rates for input to force projection models. The second application concerns the classification of Armor...methodologies for predicting pilot retention/ separation rates for input to personnel inventory projection models were e::plored. Specifically, the multilayer

  12. ANALYSIS OF A CLASSIFICATION ERROR MATRIX USING CATEGORICAL DATA TECHNIQUES.

    USGS Publications Warehouse

    Rosenfield, George H.; Fitzpatrick-Lins, Katherine

    1984-01-01

    Summary form only given. A classification error matrix typically contains tabulation results of an accuracy evaluation of a thematic classification, such as that of a land use and land cover map. The diagonal elements of the matrix represent the counts corrected, and the usual designation of classification accuracy has been the total percent correct. The nondiagonal elements of the matrix have usually been neglected. The classification error matrix is known in statistical terms as a contingency table of categorical data. As an example, an application of these methodologies to a problem of remotely sensed data concerning two photointerpreters and four categories of classification indicated that there is no significant difference in the interpretation between the two photointerpreters, and that there are significant differences among the interpreted category classifications. However, two categories, oak and cottonwood, are not separable in classification in this experiment at the 0. 51 percent probability. A coefficient of agreement is determined for the interpreted map as a whole, and individually for each of the interpreted categories. A conditional coefficient of agreement for the individual categories is compared to other methods for expressing category accuracy which have already been presented in the remote sensing literature.

  13. Italy-Japan agreement and discrepancies in diagnosis of superficial gastric lesions.

    PubMed

    Vindigni, Carla; Marini, Mario; Cevenini, Gabriele; Raffaella Ambrosio, Maria; Onorati, Monica; Frosini, Giorgio; Gotoda, Takuji; Taniguchi, Hirokazu; Tosi, Piero

    2010-01-01

    The agreement between Italian and Japanese endoscopists and pathologists on endoscopic and histopathological diagnoses of superficial gastric lesions is verified with the use of Paris and Vienna classifications. The correlations between Paris endoscopic types and Vienna histopathological categories is high in both the independent Italian and Japanese evaluations. However, the agreement between Italian and Japanese endoscopists is moderate due to the difficult evaluation of the height of the lesions, in particular when they are mixed. The agreement on the size of the lesions is fairly good. The probability of the same allocation to the Vienna categories of a single case is 87 per cent, disagreements remaining in dysplasia grading, between dysplasia, not only high-grade but also low-grade, and in situ carcinoma, and on cancer invasion of the lamina propria. The results indicate that use of the Paris and Vienna classifications has reduced the discrepancies between Western and Japanese endoscopists and pathologists in the diagnosis of these lesions.

  14. 77 FR 58592 - Modified Norway Post Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-21

    ... Modified Norway Post Agreement AGENCY: Postal Regulatory Commission. ACTION: Notice. SUMMARY: The Commission is noticing a recently-filed Postal Service request to include a modified Norway Post Agreement... existing bilateral agreement for inbound competitive services with Posten Norge AS (Modified Norway...

  15. 22 CFR 120.23 - Distribution agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Distribution agreement. 120.23 Section 120.23 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS PURPOSE AND DEFINITIONS § 120.23 Distribution agreement. An agreement (e.g., a contract) to establish a warehouse...

  16. 22 CFR 120.23 - Distribution agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Distribution agreement. 120.23 Section 120.23 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS PURPOSE AND DEFINITIONS § 120.23 Distribution agreement. An agreement (e.g., a contract) to establish a warehouse...

  17. 22 CFR 120.23 - Distribution agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Distribution agreement. 120.23 Section 120.23 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS PURPOSE AND DEFINITIONS § 120.23 Distribution agreement. An agreement (e.g., a contract) to establish a warehouse...

  18. 22 CFR 120.23 - Distribution agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Distribution agreement. 120.23 Section 120.23 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS PURPOSE AND DEFINITIONS § 120.23 Distribution agreement. An agreement (e.g., a contract) to establish a warehouse...

  19. 22 CFR 120.23 - Distribution agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Distribution agreement. 120.23 Section 120.23 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS PURPOSE AND DEFINITIONS § 120.23 Distribution agreement. An agreement (e.g., a contract) to establish a warehouse...

  20. 75 FR 44261 - Notice of Agreement Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-28

    ... agreement under the Shipping Act of 1984. Interested parties may submit comments on the agreement to the... Agreement. Parties: COSCO Container Lines Company, Limited; Kawasaki Kisen Kaisha, Ltd.; Yangming (UK) Ltd.; and Hanjin Shipping Co., Ltd. Filing Party: Amy Cano; Nixon Peabody LLP; 555 West Fifth Street,...

  1. 78 FR 36781 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-19

    ... under the Shipping Act of 1984. Interested parties may submit comments on the agreements to the... . Agreement No.: 012211. Title: COSCON/Zim Slot Charter Agreement. Parties: COSCO Container Lines Co, Ltd. and Zim Integrated Shipping Services, Ltd. Filing Party: Wayne R. Rohde, Esq.; Cozen O'Connor; 1627...

  2. 78 FR 53455 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-29

    ... . Agreement No.: 011689-015. Title: Zim/CSCL Slot Charter Agreement. Parties: Zim Integrated Shipping Services, Ltd.; China Shipping Container Line Co., Ltd. and China Shipping Container Lines (Hong Kong) Co., Ltd... under the Shipping Act of 1984. Interested parties may submit comments on the agreements to...

  3. 76 FR 76411 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-07

    ....gov . Agreement No.: 012148. Title: CSCL/POS Slot Charter Agreement. Parties: China Shipping Container Lines Co., Ltd., China Shipping Container Lines (Hong Kong) Co., Ltd., and Hainan P O Shipping Co., Ltd... under the Shipping Act of 1984. Interested parties may submit comments on the agreements to...

  4. 43 CFR 24.5 - International agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... shall be to recommend that the United States negotiate and accede to only those international agreements... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.5 International agreements. (a) International conventions... boundaries. The authority to enter into such agreements is reserved to the President by and with the...

  5. 43 CFR 24.5 - International agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... shall be to recommend that the United States negotiate and accede to only those international agreements... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.5 International agreements. (a) International conventions... boundaries. The authority to enter into such agreements is reserved to the President by and with the...

  6. The Pros and Cons of Petroleum Agreements.

    ERIC Educational Resources Information Center

    Lipton, Charles J.

    1980-01-01

    A mineral agreements expert discusses the options open to tribes, from the most standard lease form to arrangements as yet untried by Indian Nations. Discussion covers 18 basic provisions for inclusion in agreements, tax considerations, and basic forms of petroleum agreements (leases, joint ventures, production sharing, and service contracts).…

  7. 50 CFR 81.6 - Project Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Project Agreement. 81.6 Section 81.6... SPECIES OF FISH, WILDLIFE, AND PLANTS-COOPERATION WITH THE STATES § 81.6 Project Agreement. (a) Subsequent... projects for the conservation of endangered and threatened species. Financial agreements will consist of...

  8. 23 CFR 140.606 - Project agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Project agreements. 140.606 Section 140.606 Highways... Reimbursement for Bond Issue Projects § 140.606 Project agreements. Project Agreements, Form PR-2, shall be... projects. 1 The text of FHWA Form PR-2 is found in 23 CFR part 630, subpart C, appendix A....

  9. 23 CFR 633.206 - Project agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Project agreements. 633.206 Section 633.206 Highways... CONTRACT PROVISIONS Federal-Aid Contracts (Appalachian Contracts) § 633.206 Project agreements. (a) Project agreements executed for projects under the Appalachian program shall contain the following paragraphs:...

  10. 75 FR 3466 - Notice of Agreement Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Notice of Agreement Filed The Commission hereby gives notice of the filing of the following agreement under the Shipping Act of 1984. Interested parties may submit comments on the agreement to the Secretary, Federal Maritime Commission,...

  11. 48 CFR 519.7010 - Agreement contents.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Agreement contents. 519.7010 Section 519.7010 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS GSA Mentor-Protégé Program 519.7010 Agreement contents. The contents of the Agreement must contain: (a)...

  12. 48 CFR 1819.7206 - Agreement contents.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Agreement contents. 1819.7206 Section 1819.7206 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7206 Agreement contents. Each mentor-protégé agreement...

  13. 48 CFR 519.7010 - Agreement contents.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Agreement contents. 519.7010 Section 519.7010 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS GSA Mentor-Protégé Program 519.7010 Agreement contents. The contents of the Agreement must contain: (a)...

  14. 48 CFR 519.7010 - Agreement contents.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Agreement contents. 519.7010 Section 519.7010 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS GSA Mentor-Protégé Program 519.7010 Agreement contents. The contents of the Agreement must contain: (a)...

  15. 48 CFR 519.7010 - Agreement contents.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Agreement contents. 519.7010 Section 519.7010 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS GSA Mentor-Protégé Program 519.7010 Agreement contents. The contents of the Agreement must contain: (a)...

  16. 48 CFR 1819.7206 - Agreement contents.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Agreement contents. 1819.7206 Section 1819.7206 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7206 Agreement contents. Each mentor-protégé agreement...

  17. 48 CFR 1819.7206 - Agreement contents.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Agreement contents. 1819.7206 Section 1819.7206 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7206 Agreement contents. Each mentor-protégé agreement...

  18. 48 CFR 1819.7206 - Agreement contents.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Agreement contents. 1819.7206 Section 1819.7206 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7206 Agreement contents. Each mentor-protégé agreement...

  19. 48 CFR 1819.7206 - Agreement contents.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Agreement contents. 1819.7206 Section 1819.7206 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7206 Agreement contents. Each mentor-protégé agreement...

  20. 76 FR 67440 - Market Access Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-01

    ... Market Access Agreement AGENCY: Farm Credit Administration. ACTION: Notice of Draft Second Amended and Restated Market Access Agreement; request for comments. SUMMARY: The Farm Credit Administration (FCA or we) is publishing for comment the Draft Second Amended and Restated Market Access Agreement (Draft...

  1. 76 FR 77998 - Market Access Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-15

    ... Market Access Agreement AGENCY: Farm Credit Administration. ACTION: Notice of approval of the Draft Second Amended and Restated Market Access Agreement. SUMMARY: The Farm Credit Administration (FCA) announces that it has approved the Draft Second Amended and Restated Market Access Agreement (Draft...

  2. 76 FR 30360 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ... No: 2011-12970] FEDERAL MARITIME COMMISSION Notice of Agreements Filed The Commission hereby gives... submit comments on the agreements to the Secretary, Federal Maritime Commission, Washington, DC 20573... Discussion Agreement. Parties: BBC Chartering & Logistic GMBH & Co. KG; Industrial Maritime Carriers...

  3. 7 CFR 966.111 - Marketing Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Marketing Agreement. 966.111 Section 966.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... and Regulations Definitions § 966.111 Marketing Agreement. Marketing Agreement means...

  4. 7 CFR 966.111 - Marketing Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Marketing Agreement. 966.111 Section 966.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... and Regulations Definitions § 966.111 Marketing Agreement. Marketing Agreement means...

  5. 7 CFR 946.101 - Marketing agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Marketing agreement. 946.101 Section 946.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... WASHINGTON Rules and Regulations Definitions § 946.101 Marketing agreement. Marketing agreement...

  6. 7 CFR 917.101 - Marketing agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Marketing agreement. 917.101 Section 917.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... CALIFORNIA Rules and Regulations Definitions § 917.101 Marketing agreement. Marketing agreement...

  7. 7 CFR 946.101 - Marketing agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Marketing agreement. 946.101 Section 946.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... WASHINGTON Rules and Regulations Definitions § 946.101 Marketing agreement. Marketing agreement...

  8. 7 CFR 966.111 - Marketing Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Marketing Agreement. 966.111 Section 966.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... and Regulations Definitions § 966.111 Marketing Agreement. Marketing Agreement means...

  9. 7 CFR 966.111 - Marketing Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Marketing Agreement. 966.111 Section 966.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... and Regulations Definitions § 966.111 Marketing Agreement. Marketing Agreement means...

  10. 7 CFR 917.101 - Marketing agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Marketing agreement. 917.101 Section 917.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... CALIFORNIA Rules and Regulations Definitions § 917.101 Marketing agreement. Marketing agreement...

  11. 7 CFR 917.101 - Marketing agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Marketing agreement. 917.101 Section 917.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... CALIFORNIA Rules and Regulations Definitions § 917.101 Marketing agreement. Marketing agreement...

  12. 7 CFR 946.101 - Marketing agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Marketing agreement. 946.101 Section 946.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... WASHINGTON Rules and Regulations Definitions § 946.101 Marketing agreement. Marketing agreement...

  13. 7 CFR 946.101 - Marketing agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Marketing agreement. 946.101 Section 946.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... WASHINGTON Rules and Regulations Definitions § 946.101 Marketing agreement. Marketing agreement...

  14. 7 CFR 917.101 - Marketing agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Marketing agreement. 917.101 Section 917.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... CALIFORNIA Rules and Regulations Definitions § 917.101 Marketing agreement. Marketing agreement...

  15. 7 CFR 917.101 - Marketing agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Marketing agreement. 917.101 Section 917.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... CALIFORNIA Rules and Regulations Definitions § 917.101 Marketing agreement. Marketing agreement...

  16. 7 CFR 946.101 - Marketing agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Marketing agreement. 946.101 Section 946.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... WASHINGTON Rules and Regulations Definitions § 946.101 Marketing agreement. Marketing agreement...

  17. 7 CFR 966.111 - Marketing Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Marketing Agreement. 966.111 Section 966.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... and Regulations Definitions § 966.111 Marketing Agreement. Marketing Agreement means...

  18. 78 FR 33864 - Negotiated Service Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-05

    ...\\ The Modification pertains to rates for an inbound product the Agreement referred to as ``yet to be launched.'' Notice at 1. Pursuant to the Agreement, prior to launching the anticipated product, the Postal... Postal Service Multi-Product Bilateral Negotiated Service Agreement, May 29, 2013 (Notice); see...

  19. 49 CFR 605.14 - Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... TRANSPORTATION SCHOOL BUS OPERATIONS School Bus Agreements § 605.14 Agreement. Except as provided in § 605.11 no... entered into a written agreement that the applicant will not engage in school bus operations exclusively for the transportation of students and school personnel in competition with private school...

  20. 49 CFR 605.14 - Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... TRANSPORTATION SCHOOL BUS OPERATIONS School Bus Agreements § 605.14 Agreement. Except as provided in § 605.11 no... entered into a written agreement that the applicant will not engage in school bus operations exclusively for the transportation of students and school personnel in competition with private school...

  1. 49 CFR 605.14 - Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... TRANSPORTATION SCHOOL BUS OPERATIONS School Bus Agreements § 605.14 Agreement. Except as provided in § 605.11 no... entered into a written agreement that the applicant will not engage in school bus operations exclusively for the transportation of students and school personnel in competition with private school...

  2. 49 CFR 605.14 - Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... TRANSPORTATION SCHOOL BUS OPERATIONS School Bus Agreements § 605.14 Agreement. Except as provided in § 605.11 no... entered into a written agreement that the applicant will not engage in school bus operations exclusively for the transportation of students and school personnel in competition with private school...

  3. 49 CFR 605.14 - Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... TRANSPORTATION SCHOOL BUS OPERATIONS School Bus Agreements § 605.14 Agreement. Except as provided in § 605.11 no... entered into a written agreement that the applicant will not engage in school bus operations exclusively for the transportation of students and school personnel in competition with private school...

  4. 10 CFR 603.1240 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Cooperative agreement. 603.1240 Section 603.1240 Energy... Used in this Part § 603.1240 Cooperative agreement. A legal instrument which, consistent with 31 U.S.C... carrying out the activity contemplated by the cooperative agreement. The term does not include...

  5. 32 CFR 21.640 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Cooperative agreement. 21.640 Section 21.640... REGULATIONS DoD GRANTS AND AGREEMENTS-GENERAL MATTERS Definitions § 21.640 Cooperative agreement. A legal... of Defense and the recipient when carrying out the activity contemplated by the cooperative...

  6. 38 CFR 48.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Cooperative agreement. 48...) GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 48.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  7. 29 CFR 1472.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 4 2014-07-01 2014-07-01 false Cooperative agreement. 1472.620 Section 1472.620 Labor... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1472.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C. 6305, is used...

  8. 29 CFR 1472.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 4 2013-07-01 2013-07-01 false Cooperative agreement. 1472.620 Section 1472.620 Labor... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1472.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C. 6305, is used...

  9. 14 CFR 1267.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Cooperative agreement. 1267.620 Section... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1267.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C. 6305, is used...

  10. 32 CFR 26.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Cooperative agreement. 26.620 Section 26.620... Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U... recipient when carrying out the activity contemplated by the award. The term does not include...

  11. 29 CFR 1472.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 4 2012-07-01 2012-07-01 false Cooperative agreement. 1472.620 Section 1472.620 Labor... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1472.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C. 6305, is used...

  12. 32 CFR 21.640 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false Cooperative agreement. 21.640 Section 21.640... REGULATIONS DoD GRANTS AND AGREEMENTS-GENERAL MATTERS Definitions § 21.640 Cooperative agreement. A legal... of Defense and the recipient when carrying out the activity contemplated by the cooperative...

  13. 29 CFR 1472.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 4 2011-07-01 2011-07-01 false Cooperative agreement. 1472.620 Section 1472.620 Labor... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1472.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C. 6305, is used...

  14. 2 CFR 182.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Cooperative agreement. 182.620 Section 182...-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 182.620 Cooperative agreement. Cooperative... activity contemplated by the award. The term does not include cooperative research and...

  15. 7 CFR 1491.20 - Cooperative agreements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Cooperative agreements. 1491.20 Section 1491.20... OF AGRICULTURE EXPORT PROGRAMS FARM AND RANCH LANDS PROTECTION PROGRAM Cooperative Agreements and Conservation Easement Deeds § 1491.20 Cooperative agreements. (a) NRCS, on behalf of the CCC, will enter into...

  16. 45 CFR 630.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Cooperative agreement. 630.620 Section 630.620... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 630.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  17. 32 CFR 21.640 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false Cooperative agreement. 21.640 Section 21.640... REGULATIONS DoD GRANTS AND AGREEMENTS-GENERAL MATTERS Definitions § 21.640 Cooperative agreement. A legal... of Defense and the recipient when carrying out the activity contemplated by the cooperative...

  18. 45 CFR 630.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Cooperative agreement. 630.620 Section 630.620... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 630.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  19. 43 CFR 24.6 - Cooperative agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false Cooperative agreements. 24.6 Section 24.6... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.6 Cooperative agreements. (a) By reason of the... cooperative agreements for a variety of fish and wildlife programs on Federal lands. This practice shall...

  20. 38 CFR 48.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Cooperative agreement. 48...) GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 48.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  1. 29 CFR 1472.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Cooperative agreement. 1472.620 Section 1472.620 Labor... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1472.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C. 6305, is used...

  2. 7 CFR 1491.20 - Cooperative agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Cooperative agreements. 1491.20 Section 1491.20... OF AGRICULTURE EXPORT PROGRAMS FARM AND RANCH LANDS PROTECTION PROGRAM Cooperative Agreements and Conservation Easement Deeds § 1491.20 Cooperative agreements. (a) NRCS, on behalf of the CCC, will enter into...

  3. 43 CFR 24.6 - Cooperative agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true Cooperative agreements. 24.6 Section 24.6... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.6 Cooperative agreements. (a) By reason of the... cooperative agreements for a variety of fish and wildlife programs on Federal lands. This practice shall...

  4. 14 CFR 1267.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Cooperative agreement. 1267.620 Section... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1267.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C. 6305, is used...

  5. 32 CFR 37.1260 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 1 2014-07-01 2014-07-01 false Cooperative agreement. 37.1260 Section 37.1260... REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Definitions of Terms Used in This Part § 37.1260 Cooperative... the cooperative agreement. The term does not include “cooperative research and development...

  6. 10 CFR 603.1240 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Cooperative agreement. 603.1240 Section 603.1240 Energy... Used in this Part § 603.1240 Cooperative agreement. A legal instrument which, consistent with 31 U.S.C... carrying out the activity contemplated by the cooperative agreement. The term does not include...

  7. 32 CFR 21.640 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Cooperative agreement. 21.640 Section 21.640... REGULATIONS DoD GRANTS AND AGREEMENTS-GENERAL MATTERS Definitions § 21.640 Cooperative agreement. A legal... of Defense and the recipient when carrying out the activity contemplated by the cooperative...

  8. 32 CFR 21.640 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 1 2014-07-01 2014-07-01 false Cooperative agreement. 21.640 Section 21.640... REGULATIONS DoD GRANTS AND AGREEMENTS-GENERAL MATTERS Definitions § 21.640 Cooperative agreement. A legal... of Defense and the recipient when carrying out the activity contemplated by the cooperative...

  9. 32 CFR 37.1260 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false Cooperative agreement. 37.1260 Section 37.1260... REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Definitions of Terms Used in This Part § 37.1260 Cooperative... the cooperative agreement. The term does not include “cooperative research and development...

  10. 43 CFR 24.6 - Cooperative agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 1 2013-10-01 2013-10-01 false Cooperative agreements. 24.6 Section 24.6... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.6 Cooperative agreements. (a) By reason of the... cooperative agreements for a variety of fish and wildlife programs on Federal lands. This practice shall...

  11. 32 CFR 26.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false Cooperative agreement. 26.620 Section 26.620... Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U... recipient when carrying out the activity contemplated by the award. The term does not include...

  12. 45 CFR 630.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Cooperative agreement. 630.620 Section 630.620... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 630.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  13. 32 CFR 26.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Cooperative agreement. 26.620 Section 26.620... Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U... recipient when carrying out the activity contemplated by the award. The term does not include...

  14. 38 CFR 48.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Cooperative agreement. 48...) GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 48.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  15. 38 CFR 48.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Cooperative agreement. 48...) GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 48.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  16. 32 CFR 26.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false Cooperative agreement. 26.620 Section 26.620... Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U... recipient when carrying out the activity contemplated by the award. The term does not include...

  17. 24 CFR 21.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Cooperative agreement. 21.620... Development GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) Definitions § 21.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  18. 32 CFR 37.1260 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Cooperative agreement. 37.1260 Section 37.1260... REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Definitions of Terms Used in This Part § 37.1260 Cooperative... the cooperative agreement. The term does not include “cooperative research and development...

  19. 32 CFR 37.1260 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false Cooperative agreement. 37.1260 Section 37.1260... REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Definitions of Terms Used in This Part § 37.1260 Cooperative... the cooperative agreement. The term does not include “cooperative research and development...

  20. 10 CFR 603.1240 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Cooperative agreement. 603.1240 Section 603.1240 Energy... Used in this Part § 603.1240 Cooperative agreement. A legal instrument which, consistent with 31 U.S.C... carrying out the activity contemplated by the cooperative agreement. The term does not include...

  1. 40 CFR 36.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Cooperative agreement. 36.620 Section... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 36.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  2. 32 CFR 26.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 1 2014-07-01 2014-07-01 false Cooperative agreement. 26.620 Section 26.620... Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U... recipient when carrying out the activity contemplated by the award. The term does not include...

  3. 45 CFR 630.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Cooperative agreement. 630.620 Section 630.620... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 630.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  4. 24 CFR 21.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Cooperative agreement. 21.620... Development GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) Definitions § 21.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  5. 45 CFR 630.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Cooperative agreement. 630.620 Section 630.620... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 630.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  6. 43 CFR 24.6 - Cooperative agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Cooperative agreements. 24.6 Section 24.6... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.6 Cooperative agreements. (a) By reason of the... cooperative agreements for a variety of fish and wildlife programs on Federal lands. This practice shall...

  7. 38 CFR 48.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Cooperative agreement. 48...) GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 48.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  8. 14 CFR 1274.207 - Extended agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... as new cooperative agreements. Continued performance within a period specified under a multiple year....207 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION COOPERATIVE AGREEMENTS WITH COMMERCIAL FIRMS Pre-Award Requirements § 1274.207 Extended agreements. (a) Multiple year...

  9. 14 CFR 1274.207 - Extended agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... as new cooperative agreements. Continued performance within a period specified under a multiple year....207 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION COOPERATIVE AGREEMENTS WITH COMMERCIAL FIRMS Pre-Award Requirements § 1274.207 Extended agreements. (a) Multiple year...

  10. 19 CFR 118.3 - Written agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Written agreement. 118.3 Section 118.3 Customs... CENTRALIZED EXAMINATION STATIONS General Provisions § 118.3 Written agreement. The applicant tentatively selected to operate a CES must sign a written agreement with CBP before commencing operations. Failure...

  11. 19 CFR 118.3 - Written agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false Written agreement. 118.3 Section 118.3 Customs... CENTRALIZED EXAMINATION STATIONS General Provisions § 118.3 Written agreement. The applicant tentatively selected to operate a CES must sign a written agreement with CBP before commencing operations. Failure...

  12. 19 CFR 118.3 - Written agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false Written agreement. 118.3 Section 118.3 Customs... CENTRALIZED EXAMINATION STATIONS General Provisions § 118.3 Written agreement. The applicant tentatively selected to operate a CES must sign a written agreement with CBP before commencing operations. Failure...

  13. 19 CFR 118.3 - Written agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false Written agreement. 118.3 Section 118.3 Customs... CENTRALIZED EXAMINATION STATIONS General Provisions § 118.3 Written agreement. The applicant tentatively selected to operate a CES must sign a written agreement with CBP before commencing operations. Failure...

  14. 19 CFR 118.3 - Written agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Written agreement. 118.3 Section 118.3 Customs... CENTRALIZED EXAMINATION STATIONS General Provisions § 118.3 Written agreement. The applicant tentatively selected to operate a CES must sign a written agreement with Customs before commencing operations....

  15. 76 FR 38177 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ... Street, 46th Floor; Los Angeles, CA 90013. Synopsis: The agreement authorizes the parties to charter space in the trade from Vietnam to U.S. West Coast. Agreement No.: 012132. Title: Crowley/King Ocean Charter and Sailing Agreement. Parties: Crowley Latin America Services, LLC and King Ocean...

  16. 24 CFR 964.335 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Grant agreement. 964.335 Section... § 964.335 Grant agreement. (a) General. HUD will enter into a grant agreement with the recipients of a Family Investment Centers grant which defines the legal framework for the relationship between HUD and...

  17. 7 CFR 1776.10 - Grant agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 12 2014-01-01 2013-01-01 true Grant agreement. 1776.10 Section 1776.10 Agriculture... (CONTINUED) HOUSEHOLD WATER WELL SYSTEM GRANT PROGRAM HWWS Grants § 1776.10 Grant agreement. (a) RUS and the... grant award. RUS will furnish the form of grant agreement. No funds awarded under this part shall...

  18. 24 CFR 964.215 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Grant agreement. 964.215 Section... Grant agreement. (a) General. HUD shall enter into a grant agreement with the recipient of a technical assistance grant which defines the legal framework for the relationship between HUD and a resident council...

  19. 7 CFR 1775.13 - Grant agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 12 2014-01-01 2013-01-01 true Grant agreement. 1775.13 Section 1775.13 Agriculture... (CONTINUED) TECHNICAL ASSISTANCE GRANTS Grant Application Processing § 1775.13 Grant agreement. Applicants selected for funding will complete a grant agreement, RUS Guide 1775-1, which outlines the terms...

  20. 24 CFR 964.335 - Grant agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Grant agreement. 964.335 Section... § 964.335 Grant agreement. (a) General. HUD will enter into a grant agreement with the recipients of a Family Investment Centers grant which defines the legal framework for the relationship between HUD and...