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Sample records for agreement general conditions

  1. Agreement between self-reported and general practitioner-reported chronic conditions among multimorbid patients in primary care - results of the MultiCare Cohort Study

    PubMed Central

    2014-01-01

    Background Multimorbidity is a common phenomenon in primary care. Until now, no clinical guidelines for multimorbidity exist. For the development of these guidelines, it is necessary to know whether or not patients are aware of their diseases and to what extent they agree with their doctor. The objectives of this paper are to analyze the agreement of self-reported and general practitioner-reported chronic conditions among multimorbid patients in primary care, and to discover which patient characteristics are associated with positive agreement. Methods The MultiCare Cohort Study is a multicenter, prospective, observational cohort study of 3,189 multimorbid patients, ages 65 to 85. Data was collected in personal interviews with patients and GPs. The prevalence proportions for 32 diagnosis groups, kappa coefficients and proportions of specific agreement were calculated in order to examine the agreement of patient self-reported and general practitioner-reported chronic conditions. Logistic regression models were calculated to analyze which patient characteristics can be associated with positive agreement. Results We identified four chronic conditions with good agreement (e.g. diabetes mellitus κ = 0.80;PA = 0,87), seven with moderate agreement (e.g. cerebral ischemia/chronic stroke κ = 0.55;PA = 0.60), seventeen with fair agreement (e.g. cardiac insufficiency κ = 0.24;PA = 0.36) and four with poor agreement (e.g. gynecological problems κ = 0.05;PA = 0.10). Factors associated with positive agreement concerning different chronic diseases were sex, age, education, income, disease count, depression, EQ VAS score and nursing care dependency. For example: Women had higher odds ratios for positive agreement with their GP regarding osteoporosis (OR = 7.16). The odds ratios for positive agreement increase with increasing multimorbidity in almost all of the observed chronic conditions (OR = 1.22-2.41). Conclusions For multimorbidity research, the

  2. A General Agreement on Higher Education: GATS, Globalization, and Imperialism

    ERIC Educational Resources Information Center

    Collins, Christopher S.

    2007-01-01

    Through successive rounds of negotiations, the World Trade Organization (WTO) encourages countries to commit their higher education system to the mandates of the General Agreement on Trade in Services (GATS). The WTO is an organization committed to the aggressive trade liberalization of services like higher education. This ideology, known as…

  3. 7 CFR 765.207 - Conditions for severance agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Conditions for severance agreements. 765.207 Section 765.207 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS DIRECT LOAN SERVICING-REGULAR Protecting the Agency's...

  4. Health services under the General Agreement on Trade in Services.

    PubMed Central

    Adlung, R.; Carzaniga, A.

    2001-01-01

    The potential for trade in health services has expanded rapidly in recent decades. More efficient communication systems have helped to reduce distance-related barriers to trade; rising incomes and enhanced information have increased the mobility of patients; and internal cost pressures have led various governments to consider possibilities for increased private participation. As yet, however, health services have played only a modest role in the General Agreement on Trade in Services (GATS). It is possible that Members of the World Trade Organization have been discouraged from undertaking access commitments by the novelty of the Agreement, coordination problems between relevant agencies, widespread inexperience in concepts of services trade, a traditionally strong degree of government involvement in the health sector, and concerns about basic quality and social objectives. However, more than five years have passed since GATS entered into force, allowing hesitant administrations to familiarize themselves with its main elements and its operation in practice. The present paper is intended to contribute to this process. It provides an overview of the basic structure of GATS and of the patterns of current commitments in health services and of limitations frequently used in this context. The concluding section discusses possibilities of pursuing basic policy objectives in a more open environment and indicates issues that may have to be dealt with in current negotiations on services. PMID:11357215

  5. GENERAL: A New Solution to Detectable Byzantine Agreement Problem

    NASA Astrophysics Data System (ADS)

    Qin, Su-Juan; Wen, Qiao-Yan; Meng, Luo-Ming; Zhu, Fu-Chen

    2009-12-01

    We present a new quantum protocol for solving detectable Byzantine agreement problem between three parties by employing one quantum key distribution protocol. The protocol is suggested by a special four-qubit entangled state instead of singlet states, which shows that singlet states are not necessary to achieve detectable Byzantine agreement.

  6. 46 CFR 295.20 - General conditions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS AFFECTING SUBSIDIZED VESSELS AND OPERATORS MARITIME SECURITY PROGRAM (MSP) Maritime Security Program Operating Agreements § 295.20 General... in international commercial shipping or those that are deemed, after consultation with the...

  7. [General Agreement on Trade in Services and its implications for public health].

    PubMed

    Umaña-Peña, Román; Alvarez-Dardet, Carlos

    2005-01-01

    Due to the economic importance of the service sector and its trade potential, in 1995 the World Trade Organization (WTO) launched the General Agreement on Trade in Services with the objective of liberalizing trade in services worldwide and of establishing rules and disciplines to regulate it. Until now, the Agreement has produced few case laws on its rules and some of them are in the process of being developed, which makes the Agreement ambiguous and hampers accurate forecasting of its implications. Nevertheless, some analysts consider that certain characteristics and rules represent a threat to the funding mechanisms of public services and to the sovereignty of governments to generate their own rules. Moreover, the Agreement would lead to irreversible formalization of commitments, without the possibility of returning to previous conditions in the case of failure of the market and/or private participation. In addition, the Agreement acts against exclusive monopolies and providers and to a certain extent this will affect subsidies to local providers. The ability of the European Communities Court of Justice to enforce the implementation of competitive measures in public services has produced uncertainty because of the implications for health services. The Spanish Agreement with the WTO contains many questions that remain open, representing an opportunity for the participation of the health sector in the next negotiation rounds.

  8. 48 CFR 22.504 - General requirements for project labor agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Agreements for Federal Construction Projects 22.504 General requirements for project labor agreements. (a... contractors and subcontractors engaged in construction on the construction project to comply with the project... project labor agreement for a particular construction project and facilitate agreement on those terms......

  9. 48 CFR 22.504 - General requirements for project labor agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Agreements for Federal Construction Projects 22.504 General requirements for project labor agreements. (a... contractors and subcontractors engaged in construction on the construction project to comply with the project... project labor agreement for a particular construction project and facilitate agreement on those terms......

  10. 48 CFR 22.504 - General requirements for project labor agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Agreements for Federal Construction Projects 22.504 General requirements for project labor agreements. (a... contractors and subcontractors engaged in construction on the construction project to comply with the project... project labor agreement for a particular construction project and facilitate agreement on those terms......

  11. 48 CFR 22.504 - General requirements for project labor agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Agreements for Federal Construction Projects 22.504 General requirements for project labor agreements. (a... contractors and subcontractors engaged in construction on the construction project to comply with the project... project labor agreement for a particular construction project and facilitate agreement on those terms......

  12. 48 CFR 22.504 - General requirements for project labor agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Agreements for Federal Construction Projects 22.504 General requirements for project labor agreements. (a... contractors and subcontractors engaged in construction on the construction project to comply with the project... project labor agreement for a particular construction project and facilitate agreement on those terms......

  13. 10 CFR 950.11 - Terms and conditions of the Conditional Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Administrator has entered into Standby Support Contracts that cover three different reactor designs, and the Conditional Agreement is for an advanced nuclear facility of a different reactor design than those covered... if the advanced nuclear facility is one of the initial two reactors or one of the subsequent...

  14. 10 CFR 950.11 - Terms and conditions of the Conditional Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Administrator has entered into Standby Support Contracts that cover three different reactor designs, and the Conditional Agreement is for an advanced nuclear facility of a different reactor design than those covered... costs and to cover incremental costs, including a provision on whether the allocation shall be...

  15. 43 CFR 3280.3 - What is BLM's general policy regarding the formation of unit agreements?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) GEOTHERMAL RESOURCES UNIT AGREEMENTS Geothermal Resources Unit Agreements-General § 3280.3 What is BLM's... natural resources of any geothermal reservoir, field, or like area, or any part thereof, lessees and...

  16. 43 CFR 3280.3 - What is BLM's general policy regarding the formation of unit agreements?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) GEOTHERMAL RESOURCES UNIT AGREEMENTS Geothermal Resources Unit Agreements-General § 3280.3 What is BLM's... natural resources of any geothermal reservoir, field, or like area, or any part thereof, lessees and...

  17. 43 CFR 3280.3 - What is BLM's general policy regarding the formation of unit agreements?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) GEOTHERMAL RESOURCES UNIT AGREEMENTS Geothermal Resources Unit Agreements-General § 3280.3 What is BLM's... natural resources of any geothermal reservoir, field, or like area, or any part thereof, lessees and...

  18. 43 CFR 3280.3 - What is BLM's general policy regarding the formation of unit agreements?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) GEOTHERMAL RESOURCES UNIT AGREEMENTS Geothermal Resources Unit Agreements-General § 3280.3 What is BLM's... natural resources of any geothermal reservoir, field, or like area, or any part thereof, lessees and...

  19. Conditioned Fear Acquisition and Generalization in Generalized Anxiety Disorder.

    PubMed

    Tinoco-González, Daniella; Fullana, Miquel Angel; Torrents-Rodas, David; Bonillo, Albert; Vervliet, Bram; Blasco, María Jesús; Farré, Magí; Torrubia, Rafael

    2015-09-01

    Abnormal fear conditioning processes (including fear acquisition and conditioned fear-generalization) have been implicated in the pathogenesis of anxiety disorders. Previous research has shown that individuals with panic disorder present enhanced conditioned fear-generalization in comparison to healthy controls. Enhanced conditioned fear-generalization could also characterize generalized anxiety disorder (GAD), but research so far is inconclusive. An important confounding factor in previous research is comorbidity. The present study examined conditioned fear-acquisition and fear-generalization in 28 patients with GAD and 30 healthy controls using a recently developed fear acquisition and generalization paradigm assessing fear-potentiated startle and online expectancies of the unconditioned stimulus. Analyses focused on GAD patients without comorbidity but included also patients with comorbid anxiety disorders. Patients and controls did not differ as regards fear acquisition. However, contrary to our hypothesis, both groups did not differ either in most indexes of conditioned fear-generalization. Moreover, dimensional measures of GAD symptoms were not correlated with conditioned fear-generalization indexes. Comorbidity did not have a significant impact on the results. Our data suggest that conditioned fear-generalization is not enhanced in GAD. Results are discussed with special attention to the possible effects of comorbidity on fear learning abnormalities.

  20. 32 CFR 536.105 - Responsibilities generally/international agreements claims.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 3 2014-07-01 2014-07-01 false Responsibilities generally/international... THE ARMY CLAIMS AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES Claims Cognizable Under International Agreements § 536.105 Responsibilities generally/international agreements claims. (a) The Commander USARCS...

  1. 32 CFR 536.105 - Responsibilities generally/international agreements claims.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Responsibilities generally/international... THE ARMY CLAIMS AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES Claims Cognizable Under International Agreements § 536.105 Responsibilities generally/international agreements claims. (a) The Commander USARCS...

  2. 32 CFR 536.105 - Responsibilities generally/international agreements claims.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 3 2012-07-01 2009-07-01 true Responsibilities generally/international... THE ARMY CLAIMS AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES Claims Cognizable Under International Agreements § 536.105 Responsibilities generally/international agreements claims. (a) The Commander USARCS...

  3. 32 CFR 536.105 - Responsibilities generally/international agreements claims.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 3 2011-07-01 2009-07-01 true Responsibilities generally/international... THE ARMY CLAIMS AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES Claims Cognizable Under International Agreements § 536.105 Responsibilities generally/international agreements claims. (a) The Commander USARCS...

  4. 32 CFR 536.105 - Responsibilities generally/international agreements claims.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 3 2013-07-01 2013-07-01 false Responsibilities generally/international... THE ARMY CLAIMS AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES Claims Cognizable Under International Agreements § 536.105 Responsibilities generally/international agreements claims. (a) The Commander USARCS...

  5. 18 CFR 415.50 - General conditions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false General conditions. 415.50 Section 415.50 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL BASIN REGULATIONS-FLOOD PLAIN REGULATIONS Enforcement § 415.50 General conditions. On...

  6. 18 CFR 415.50 - General conditions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false General conditions. 415.50 Section 415.50 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL BASIN REGULATIONS-FLOOD PLAIN REGULATIONS Enforcement § 415.50 General conditions. On...

  7. 78 FR 45194 - General Electric Company; Analysis of Proposed Agreement Containing Consent Order To Aid Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-26

    ... General Electric Company; Analysis of Proposed Agreement Containing Consent Order To Aid Public Comment... section below. Write ``General Electric, File No. 131 0069'' on your comment and file your comment online...'') with General Electric Company (``GE''), which is designed to remedy the anticompetitive effects of...

  8. The General Agreement on Trade in Services and Educational Services: An Australian Perspective

    ERIC Educational Resources Information Center

    Tangas, Jim; Calderon, Angel J.

    2004-01-01

    This paper discusses the implications for higher education of the World Trade Organisation (WTO) negotiations towards the General Agreement on Trade in Services (GATS; see http://www.wto.org/) from the perspective of Australian educational institutions.

  9. Charge regulation: A generalized boundary condition?

    NASA Astrophysics Data System (ADS)

    Markovich, Tomer; Andelman, David; Podgornik, Rudi

    2016-01-01

    The three most commonly used boundary conditions for charged colloidal systems are constant charge (insulator), constant potential (conducting electrode) and charge regulation (ionizable groups at the surface). It is usually believed that the charge regulation is a generalized boundary condition that reduces in some specific limits to either constant-charge or constant-potential boundary conditions. By computing the disjoining pressure between two symmetric planes for these three boundary conditions, both numerically (for all inter-plate separations) and analytically (for small inter-plate separations), we show that this is not, in general, the case. In fact, the limit of charge regulation is a separate boundary condition, yielding a disjoining pressure with a different characteristic separation scaling. Our findings are supported by several examples demonstrating that the disjoining pressure at small separations for the charge regulation boundary condition depends on the details of the dissociation/association process.

  10. 34 CFR 675.20 - Eligible employers and general conditions and limitation on employment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... agreement with that agency or organization. The agreement must set forth the FWS work conditions. The... Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION FEDERAL WORK-STUDY PROGRAMS Federal Work-Study Program § 675.20 Eligible employers and general conditions and limitation on...

  11. 34 CFR 675.20 - Eligible employers and general conditions and limitation on employment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... agreement with that agency or organization. The agreement must set forth the FWS work conditions. The... Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION FEDERAL WORK-STUDY PROGRAMS Federal Work-Study Program § 675.20 Eligible employers and general conditions and limitation on...

  12. 34 CFR 675.20 - Eligible employers and general conditions and limitation on employment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... agreement with that agency or organization. The agreement must set forth the FWS work conditions. The... Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION FEDERAL WORK-STUDY PROGRAMS Federal Work-Study Program § 675.20 Eligible employers and general conditions and limitation on...

  13. 34 CFR 675.20 - Eligible employers and general conditions and limitation on employment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... agreement with that agency or organization. The agreement must set forth the FWS work conditions. The... Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION FEDERAL WORK-STUDY PROGRAMS Federal Work-Study Program § 675.20 Eligible employers and general conditions and limitation on...

  14. 44 CFR 360.5 - General provisions for State Cooperative Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false General provisions for State Cooperative Agreement. 360.5 Section 360.5 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS STATE ASSISTANCE PROGRAMS FOR TRAINING AND...

  15. 46 CFR 356.21 - General approval of standard loan or mortgage agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false General approval of standard loan or mortgage agreements. 356.21 Section 356.21 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION MISCELLANEOUS REQUIREMENTS FOR VESSELS OF 100 FEET OR GREATER IN REGISTERED LENGTH TO OBTAIN A FISHERY ENDORSEMENT TO...

  16. 46 CFR 356.21 - General approval of standard loan or mortgage agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false General approval of standard loan or mortgage agreements. 356.21 Section 356.21 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION MISCELLANEOUS REQUIREMENTS FOR VESSELS OF 100 FEET OR GREATER IN REGISTERED LENGTH TO OBTAIN A FISHERY ENDORSEMENT TO...

  17. 46 CFR 356.21 - General approval of standard loan or mortgage agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false General approval of standard loan or mortgage agreements. 356.21 Section 356.21 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION MISCELLANEOUS REQUIREMENTS FOR VESSELS OF 100 FEET OR GREATER IN REGISTERED LENGTH TO OBTAIN A FISHERY ENDORSEMENT TO...

  18. 46 CFR 356.21 - General approval of standard loan or mortgage agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false General approval of standard loan or mortgage agreements. 356.21 Section 356.21 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION MISCELLANEOUS REQUIREMENTS FOR VESSELS OF 100 FEET OR GREATER IN REGISTERED LENGTH TO OBTAIN A FISHERY ENDORSEMENT TO...

  19. 46 CFR 356.21 - General approval of standard loan or mortgage agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 8 2012-10-01 2012-10-01 false General approval of standard loan or mortgage agreements. 356.21 Section 356.21 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION MISCELLANEOUS REQUIREMENTS FOR VESSELS OF 100 FEET OR GREATER IN REGISTERED LENGTH TO OBTAIN A FISHERY ENDORSEMENT TO...

  20. Asymmetrical Stimulus Generalization following Differential Fear Conditioning

    PubMed Central

    Bang, Sun Jung; Allen, Timothy A.; Jones, Lauren K.; Boguszewski, Pawel; Brown, Thomas H.

    2008-01-01

    Rodent ultrasonic vocalizations (USVs) are ethologically critical social signals. Rats emit 22 kHz USVs and 50 kHz USVs, respectively, in conjunction with negative and positive affective states. Little is known about what controls emotional reactivity to these social signals. Using male Sprague-Dawley rats, we examined unconditional and conditional freezing behavior in response to the following auditory stimuli: three 22 kHz USVs, a discontinuous tone whose frequency and on-off pattern matched one of the USVs, a continuous tone with the same or lower frequencies, a 4 kHz discontinuous tone with an on-off pattern matched to one of the USVs, and a 50 kHz USV. There were no differences among these stimuli in terms of the unconditional elicitation of freezing behavior. Thus, the stimuli were equally neutral before conditioning. During differential fear conditioning, one of these stimuli (the CS+) always co-terminated with a footshock unconditional stimulus (US) and another stimulus (the CS−) was explicitly unpaired with the US. There were no significant differences among these cues in CS+-elicited freezing behavior. Thus, the stimuli were equally salient or effective as cues in supporting fear conditioning. When the CS+ was a 22 kHz USV or a similar stimulus, rats discriminated based on the principal frequency and/or the temporal pattern of the stimulus. However, when these same stimuli served as the CS−, discrimination failed due to generalization from the CS+. Thus, the stimuli differed markedly in the specificity of conditioning. This strikingly asymmetrical stimulus generalization is a novel bias in discrimination. PMID:18434217

  1. 46 CFR 296.30 - General conditions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... considering replacement vessels described in § 296.21(e), and for vessels eligible under the third and fourth... Eligible Vessel to be included in an MSP Operating Agreement that is on charter to the U.S. Government... MSP Operating Agreement shall be: (i) The expiration or termination date of the Government...

  2. 46 CFR 296.30 - General conditions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... considering replacement vessels described in § 296.21(e), and for vessels eligible under the third and fourth... Eligible Vessel to be included in an MSP Operating Agreement that is on charter to the U.S. Government... MSP Operating Agreement shall be: (i) The expiration or termination date of the Government...

  3. 46 CFR 296.30 - General conditions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... considering replacement vessels described in § 296.21(e), and for vessels eligible under the third and fourth... Eligible Vessel to be included in an MSP Operating Agreement that is on charter to the U.S. Government... MSP Operating Agreement shall be: (i) The expiration or termination date of the Government...

  4. Market conditions and general practitioners' referrals.

    PubMed

    Iversen, Tor; Ma, Ching-to Albert

    2011-12-01

    We study how market conditions influence referrals of patients by general practitioners (GPs). We set up a model of GP referral for the Norwegian health care system, where a GP receives capitation payment based on the number of patients in his practice, as well as fee-for-service reimbursements. A GP may accept new patients or close the practice to new patients. We model GPs as partially altruistic, and compete for patients. We show that a GP operating in a more competitive market has a higher referral rate. To compete for patients and to retain them, a GP satisfies patients' requests for referrals. Furthermore, a GP who faces a patient shortage will refer more often than a GP who does not. Tests with Norwegian GP radiology referral data support our theory. PMID:22009482

  5. General conditions for quantum adiabatic evolution

    SciTech Connect

    Comparat, Daniel

    2009-07-15

    Adiabaticity occurs when, during its evolution, a physical system remains in the instantaneous eigenstate of the Hamiltonian. Unfortunately, existing results, such as the quantum adiabatic theorem based on a slow down evolution [H({epsilon}t),{epsilon}{yields}0], are insufficient to describe an evolution driven by the Hamiltonian H(t) itself. Here we derive general criteria and exact bounds, for the state and its phase, ensuring an adiabatic evolution for any Hamiltonian H(t). As a corollary, we demonstrate that the commonly used condition of a slow Hamiltonian variation rate, compared to the spectral gap, is indeed sufficient to ensure adiabaticity but only when the Hamiltonian is real and nonoscillating (for instance, containing exponential or polynomial but no sinusoidal functions)

  6. 14 CFR 201.7 - General certificate conditions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Agreement 18900 (OST Form 4523), and a tariff (for those carriers otherwise generally required to file tariffs) that includes its terms, and that the holder comply with all other requirements of part 203....

  7. Assessment of individual agreements with repeated measurements based on generalized confidence intervals.

    PubMed

    Quiroz, Jorge; Burdick, Richard K

    2009-01-01

    Individual agreement between two measurement systems is determined using the total deviation index (TDI) or the coverage probability (CP) criteria as proposed by Lin (2000) and Lin et al. (2002). We used a variance component model as proposed by Choudhary (2007). Using the bootstrap approach, Choudhary (2007), and generalized confidence intervals, we construct bounds on TDI and CP. A simulation study was conducted to assess whether the bounds maintain the stated type I error probability of the test. We also present a computational example to demonstrate the statistical methods described in the paper.

  8. Distance health services under the general agreement on trade in services.

    PubMed

    Yeo, Matthew S

    2002-01-01

    This Article discusses the state of distance health with respect to the General Agreement on Trade in Services (GATS). After examining the various aspects of telemedicine and its place in international trade, the author looks at the structure and functioning of GATS and how telemedicine is regulated under this agreement. The author argues that the potential for telemedicine under this agreement has yet to be fulfilled and suggests a number of ways to realize its potential. Ultimately, however, the author concludes that the single most important international trade objective for the United States healthcare industry should be to get its own house in order with respect to cross-border provision of health services. From an international trade perspective, the problem of non-uniform state licensure requirements within the United States makes it very difficult for the United States to negotiate market access commitments for distance health services with other countries. Therefore, it is not realistic to expect significant progress in the liberalization of distance health services until the United States has in place a reasonably uniform domestic system of licensure and regulation for telemedicine practitioners. PMID:11974523

  9. 47 CFR 18.111 - General operating conditions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false General operating conditions. 18.111 Section 18.111 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND MEDICAL EQUIPMENT General Information § 18.111 General operating conditions. (a) Persons operating ISM...

  10. 47 CFR 18.111 - General operating conditions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false General operating conditions. 18.111 Section 18.111 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND MEDICAL EQUIPMENT General Information § 18.111 General operating conditions. (a) Persons operating ISM...

  11. 47 CFR 18.111 - General operating conditions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false General operating conditions. 18.111 Section 18.111 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND MEDICAL EQUIPMENT General Information § 18.111 General operating conditions. (a) Persons operating ISM...

  12. 47 CFR 18.111 - General operating conditions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false General operating conditions. 18.111 Section 18.111 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND MEDICAL EQUIPMENT General Information § 18.111 General operating conditions. (a) Persons operating ISM...

  13. 47 CFR 18.111 - General operating conditions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false General operating conditions. 18.111 Section 18.111 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND MEDICAL EQUIPMENT General Information § 18.111 General operating conditions. (a) Persons operating ISM...

  14. Generalization of Verbal Conditioning of Study Habits

    ERIC Educational Resources Information Center

    Miller, Susan J.; Sloane, Howard N.

    1974-01-01

    This experiment attempted to condition subject's answers to a questionnaire about study-related behaviors using verbal social reinforcement and to measure the extent to which this training affected rate of studying. For five of the six subjects, significant changes in study comments resulted. (Author)

  15. 49 CFR 229.45 - General condition.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... endanger the safety of the crew, locomotive or train. These conditions include: insecure attachment of components, including third rail shoes or beams, traction motors and motor gear cases, and fuel tanks; fuel... other structural infirmities of components, including quill drives, axles, gears, pinions,...

  16. 49 CFR 229.45 - General condition.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... endanger the safety of the crew, locomotive or train. These conditions include: insecure attachment of components, including third rail shoes or beams, traction motors and motor gear cases, and fuel tanks; fuel... other structural infirmities of components, including quill drives, axles, gears, pinions,...

  17. 49 CFR 229.45 - General condition.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... endanger the safety of the crew, locomotive or train. These conditions include: insecure attachment of components, including third rail shoes or beams, traction motors and motor gear cases, and fuel tanks; fuel... other structural infirmities of components, including quill drives, axles, gears, pinions,...

  18. 49 CFR 229.45 - General condition.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... endanger the safety of the crew, locomotive or train. These conditions include: insecure attachment of components, including third rail shoes or beams, traction motors and motor gear cases, and fuel tanks; fuel... other structural infirmities of components, including quill drives, axles, gears, pinions,...

  19. 49 CFR 229.45 - General condition.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... endanger the safety of the crew, locomotive or train. These conditions include: insecure attachment of components, including third rail shoes or beams, traction motors and motor gear cases, and fuel tanks; fuel... other structural infirmities of components, including quill drives, axles, gears, pinions,...

  20. 32 CFR 37.1100 - What are my responsibilities generally as an administrative agreements officer for a TIA?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... agreement, as described in 32 CFR 22.715. Responsibilities for TIAs include: (a) Advising agreements officers before they award TIAs on how to establish award terms and conditions that better meet research... funds. (b) Participating as the business partner to the DoD program official to ensure the...

  1. 14 CFR 67.213 - General medical condition.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false General medical condition. 67.213 Section...) AIRMEN MEDICAL STANDARDS AND CERTIFICATION Second-Class Airman Medical Certificate § 67.213 General medical condition. The general medical standards for a second-class airman medical certificate are: (a)...

  2. 14 CFR 67.113 - General medical condition.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false General medical condition. 67.113 Section...) AIRMEN MEDICAL STANDARDS AND CERTIFICATION First-Class Airman Medical Certificate § 67.113 General medical condition. The general medical standards for a first-class airman medical certificate are: (a)...

  3. 14 CFR 67.313 - General medical condition.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false General medical condition. 67.313 Section...) AIRMEN MEDICAL STANDARDS AND CERTIFICATION Third-Class Airman Medical Certificate § 67.313 General medical condition. The general medical standards for a third-class airman medical certificate are: (a)...

  4. 14 CFR 67.213 - General medical condition.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false General medical condition. 67.213 Section...) AIRMEN MEDICAL STANDARDS AND CERTIFICATION Second-Class Airman Medical Certificate § 67.213 General medical condition. The general medical standards for a second-class airman medical certificate are: (a)...

  5. 14 CFR 67.113 - General medical condition.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false General medical condition. 67.113 Section...) AIRMEN MEDICAL STANDARDS AND CERTIFICATION First-Class Airman Medical Certificate § 67.113 General medical condition. The general medical standards for a first-class airman medical certificate are: (a)...

  6. 14 CFR 67.113 - General medical condition.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false General medical condition. 67.113 Section...) AIRMEN MEDICAL STANDARDS AND CERTIFICATION First-Class Airman Medical Certificate § 67.113 General medical condition. The general medical standards for a first-class airman medical certificate are: (a)...

  7. 14 CFR 67.313 - General medical condition.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false General medical condition. 67.313 Section...) AIRMEN MEDICAL STANDARDS AND CERTIFICATION Third-Class Airman Medical Certificate § 67.313 General medical condition. The general medical standards for a third-class airman medical certificate are: (a)...

  8. 14 CFR 67.213 - General medical condition.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false General medical condition. 67.213 Section...) AIRMEN MEDICAL STANDARDS AND CERTIFICATION Second-Class Airman Medical Certificate § 67.213 General medical condition. The general medical standards for a second-class airman medical certificate are: (a)...

  9. 14 CFR 67.313 - General medical condition.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false General medical condition. 67.313 Section...) AIRMEN MEDICAL STANDARDS AND CERTIFICATION Third-Class Airman Medical Certificate § 67.313 General medical condition. The general medical standards for a third-class airman medical certificate are: (a)...

  10. 42 CFR 493.1230 - Condition: General laboratory systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 5 2012-10-01 2012-10-01 false Condition: General laboratory systems. 493.1230... SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Quality System for Nonwaived Testing General Laboratory Systems § 493.1230 Condition: General laboratory systems. Each laboratory...

  11. 42 CFR 493.1230 - Condition: General laboratory systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 5 2013-10-01 2013-10-01 false Condition: General laboratory systems. 493.1230... SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Quality System for Nonwaived Testing General Laboratory Systems § 493.1230 Condition: General laboratory systems. Each laboratory...

  12. 42 CFR 493.1230 - Condition: General laboratory systems.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 5 2014-10-01 2014-10-01 false Condition: General laboratory systems. 493.1230... SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Quality System for Nonwaived Testing General Laboratory Systems § 493.1230 Condition: General laboratory systems. Each laboratory...

  13. 42 CFR 493.1230 - Condition: General laboratory systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Condition: General laboratory systems. 493.1230... SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Quality System for Nonwaived Testing General Laboratory Systems § 493.1230 Condition: General laboratory systems. Each laboratory...

  14. 42 CFR 493.1230 - Condition: General laboratory systems.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 5 2011-10-01 2011-10-01 false Condition: General laboratory systems. 493.1230... SERVICES (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Quality System for Nonwaived Testing General Laboratory Systems § 493.1230 Condition: General laboratory systems. Each laboratory...

  15. 42 CFR 493.1208 - Condition: General immunology.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Condition: General immunology. 493.1208 Section 493....1208 Condition: General immunology. If the laboratory provides services in the subspecialty of General immunology, the laboratory must meet the requirements specified in §§ 493.1230 through 493.1256, and §§...

  16. 42 CFR 493.1208 - Condition: General immunology.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 5 2011-10-01 2011-10-01 false Condition: General immunology. 493.1208 Section 493....1208 Condition: General immunology. If the laboratory provides services in the subspecialty of General immunology, the laboratory must meet the requirements specified in §§ 493.1230 through 493.1256, and §§...

  17. 42 CFR 493.1208 - Condition: General immunology.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 5 2012-10-01 2012-10-01 false Condition: General immunology. 493.1208 Section 493....1208 Condition: General immunology. If the laboratory provides services in the subspecialty of General immunology, the laboratory must meet the requirements specified in §§ 493.1230 through 493.1256, and §§...

  18. 42 CFR 493.1208 - Condition: General immunology.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 5 2014-10-01 2014-10-01 false Condition: General immunology. 493.1208 Section 493....1208 Condition: General immunology. If the laboratory provides services in the subspecialty of General immunology, the laboratory must meet the requirements specified in §§ 493.1230 through 493.1256, and §§...

  19. 42 CFR 493.1208 - Condition: General immunology.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 5 2013-10-01 2013-10-01 false Condition: General immunology. 493.1208 Section 493....1208 Condition: General immunology. If the laboratory provides services in the subspecialty of General immunology, the laboratory must meet the requirements specified in §§ 493.1230 through 493.1256, and §§...

  20. 14 CFR 67.213 - General medical condition.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) AIRMEN MEDICAL STANDARDS AND CERTIFICATION Second-Class Airman Medical Certificate § 67.213 General medical condition. The general medical standards for a second-class airman medical certificate are: (a)...

  1. Factors Affecting the Agreement Between Emergency Psychiatrists and General Practitioners Regarding Involuntary Psychiatric Hospitalizations.

    PubMed

    Geoffroy, Pierre Alexis; Duhamel, Alain; Behal, Hélène; Zouitina-Lietaert, Nadia; Duthilleul, Julie; Marquette, Louise; Ducrocq, François; Vaiva, Guillaume; Rolland, Benjamin

    2016-06-21

    Important discrepancies exist between physicians in deciding when to perform involuntary hospitalization measures (IHMs). The factors underlying these differences are poorly known.We conducted a two-year single-center retrospective study in France on patients who were referred to the emergency department (ED) with an IHM certificate written by a private-practice General Practitioner (GP). For each consultation, the official IHM motive was categorized into four groups: Suicide; Psychosis, Mania, or Melancholia (PMM); Agitation; and Other. The alcohol status of the patient was also noted. The factors underlying the ED psychiatrists' confirmation of the use of IHMs were determined using a logistic regression model. One hundred eighty-nine cases were found (165 patients; 44.2 ± 16 years, 41.3% women). The ED psychiatrists confirmed the use of IHMs in 123 instances (65.1% agreement rate). Multivariate analyses found that IHM disagreement was significantly associated with patient alcohol status and the reason for referral. Specifically, there was an increased risk of IHM disagreement when the patient had an alcohol-positive status (OR = 15.80; 95% CI [6.45-38.67]; p < 0.0001) and when the motive for IHM was "agitation" compared with "suicide" (OR = 11.44; 95% CI[3.38-38.78]; p < 0.0001). These findings reflect significant disparities between GPs and ED psychiatrists regarding the decision to proceed to an IHM.

  2. 14 CFR 203.4 - Montreal Agreement as part of airline-passenger contract and conditions of carriage.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Montreal Agreement as part of airline-passenger contract and conditions of carriage. 203.4 Section 203.4 Aeronautics and Space OFFICE OF THE... CONVENTION LIABILITY LIMITS AND DEFENSES § 203.4 Montreal Agreement as part of airline-passenger contract...

  3. 14 CFR 203.4 - Montreal Agreement as part of airline-passenger contract and conditions of carriage.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Montreal Agreement as part of airline-passenger contract and conditions of carriage. 203.4 Section 203.4 Aeronautics and Space OFFICE OF THE... CONVENTION LIABILITY LIMITS AND DEFENSES § 203.4 Montreal Agreement as part of airline-passenger contract...

  4. 14 CFR 203.4 - Montreal Agreement as part of airline-passenger contract and conditions of carriage.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Montreal Agreement as part of airline-passenger contract and conditions of carriage. 203.4 Section 203.4 Aeronautics and Space OFFICE OF THE... CONVENTION LIABILITY LIMITS AND DEFENSES § 203.4 Montreal Agreement as part of airline-passenger contract...

  5. 14 CFR 203.4 - Montreal Agreement as part of airline-passenger contract and conditions of carriage.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Montreal Agreement as part of airline-passenger contract and conditions of carriage. 203.4 Section 203.4 Aeronautics and Space OFFICE OF THE... CONVENTION LIABILITY LIMITS AND DEFENSES § 203.4 Montreal Agreement as part of airline-passenger contract...

  6. 14 CFR 203.4 - Montreal Agreement as part of airline-passenger contract and conditions of carriage.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Montreal Agreement as part of airline-passenger contract and conditions of carriage. 203.4 Section 203.4 Aeronautics and Space OFFICE OF THE... CONVENTION LIABILITY LIMITS AND DEFENSES § 203.4 Montreal Agreement as part of airline-passenger contract...

  7. Factors Affecting the Agreement Between Emergency Psychiatrists and General Practitioners Regarding Involuntary Psychiatric Hospitalizations

    PubMed Central

    Geoffroy, Pierre Alexis; Duhamel, Alain; Behal, Hélène; Zouitina-Lietaert, Nadia; Duthilleul, Julie; Marquette, Louise; Ducrocq, François; Vaiva, Guillaume; Rolland, Benjamin

    2016-01-01

    Important discrepancies exist between physicians in deciding when to perform involuntary hospitalization measures (IHMs). The factors underlying these differences are poorly known. We conducted a two-year single-center retrospective study in France on patients who were referred to the emergency department (ED) with an IHM certificate written by a private-practice General Practitioner (GP). For each consultation, the official IHM motive was categorized into four groups: Suicide; Psychosis, Mania, or Melancholia (PMM); Agitation; and Other. The alcohol status of the patient was also noted. The factors underlying the ED psychiatrists’ confirmation of the use of IHMs were determined using a logistic regression model. One hundred eighty-nine cases were found (165 patients; 44.2 ± 16 years, 41.3% women). The ED psychiatrists confirmed the use of IHMs in 123 instances (65.1% agreement rate). Multivariate analyses found that IHM disagreement was significantly associated with patient alcohol status and the reason for referral. Specifically, there was an increased risk of IHM disagreement when the patient had an alcohol-positive status (OR = 15.80; 95% CI [6.45–38.67]; p < 0.0001) and when the motive for IHM was “agitation” compared with “suicide” (OR = 11.44; 95% CI[3.38–38.78]; p < 0.0001). These findings reflect significant disparities between GPs and ED psychiatrists regarding the decision to proceed to an IHM. PMID:27324574

  8. 18 CFR 50.11 - General conditions applicable to permits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... TO SITE INTERSTATE ELECTRIC TRANSMISSION FACILITIES § 50.11 General conditions applicable to permits... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false General conditions applicable to permits. 50.11 Section 50.11 Conservation of Power and Water Resources FEDERAL...

  9. 18 CFR 50.11 - General conditions applicable to permits.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... TO SITE INTERSTATE ELECTRIC TRANSMISSION FACILITIES § 50.11 General conditions applicable to permits... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false General conditions applicable to permits. 50.11 Section 50.11 Conservation of Power and Water Resources FEDERAL...

  10. 18 CFR 154.109 - General terms and conditions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false General terms and conditions. 154.109 Section 154.109 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... Composition of Tariff § 154.109 General terms and conditions. (a) This section of the tariff contains...

  11. 18 CFR 154.109 - General terms and conditions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false General terms and conditions. 154.109 Section 154.109 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... Composition of Tariff § 154.109 General terms and conditions. (a) This section of the tariff contains...

  12. Enhanced Generalization of Auditory Conditioned Fear in Juvenile Mice

    ERIC Educational Resources Information Center

    Ito, Wataru; Pan, Bing-Xing; Yang, Chao; Thakur, Siddarth; Morozov, Alexei

    2009-01-01

    Increased emotionality is a characteristic of human adolescence, but its animal models are limited. Here we report that generalization of auditory conditioned fear between a conditional stimulus (CS+) and a novel auditory stimulus is stronger in 4-5-wk-old mice (juveniles) than in their 9-10-wk-old counterparts (adults), whereas nonassociative…

  13. Generalization of Extinguished Skin Conductance Responding in Human Fear Conditioning

    ERIC Educational Resources Information Center

    Vervliet, Bram; Vansteenwegen, Debora; Eelen, Paul

    2004-01-01

    In a human fear conditioning paradigm using the skin conductance response (SCR), participants were assigned to two groups. Following identical acquisition, group ABA (n = 16) was extinguished to a generalization stimulus (GS), whereas group AAB (n = 20) was extinguished to the conditioned stimulus (CS). At test, presenting the CS in group ABA…

  14. Diagnostic agreement between a primary care physician and a teledermatologist for common dermatological conditions in North India

    PubMed Central

    Patro, Binod Kumar; Tripathy, Jaya Prasad; De, Dipankar; Sinha, Smita; Singh, Amarjeet; Kanwar, Amrinder Jit

    2015-01-01

    Background: Primary care physicians (PCPs) encounter a large number of patients with dermatological diseases. However, delivering appropriate management is a challenge considering the inadequate dermatology training offered during the undergraduate medical curriculum. Teledermatology is the clinical evaluation of skin lesions by dermatologists and allows patients to be diagnosed and treated from a distant site. It is seen as a potential solution to the shortage of specialists and providing equitable service in remote areas. Aim: The study was aimed at estimating the diagnostic agreement of common dermatological conditions between a PCP and a teledermatologist. Materials and Methods: Consecutive patients with dermatological ailments who attended a primary health care clinic were recruited into the study, examined by the PCP and offered a diagnosis. The clinical images and patients’ history were collected and transferred to a dermatologist at a tertiary center who also made a diagnosis. Agreement between diagnosis made by the PCPs and the teledermatologist was measured using kappa (κ) statistics. Results: Overall agreement between the diagnoses made by a PCP and the dermatologist was found to be 56%. Poor κ agreement (<0.4) was seen in the diagnosis of psoriasis and eczema. Conclusion: Teledermatology can supplement specialist dermatology service in remote areas. There was poor agreement in the diagnosis of psoriasis, classifying various types of eczematous conditions and fungal infections. Scarce manpower in dermatology at the primary health care level compounded by the burden of skin ailments necessitates training of PCPs in common dermatological conditions. PMID:25657912

  15. A generalized conditional heteroscedastic model for temperature downscaling

    NASA Astrophysics Data System (ADS)

    Modarres, R.; Ouarda, T. B. M. J.

    2014-11-01

    This study describes a method for deriving the time varying second order moment, or heteroscedasticity, of local daily temperature and its association to large Coupled Canadian General Circulation Models predictors. This is carried out by applying a multivariate generalized autoregressive conditional heteroscedasticity (MGARCH) approach to construct the conditional variance-covariance structure between General Circulation Models (GCMs) predictors and maximum and minimum temperature time series during 1980-2000. Two MGARCH specifications namely diagonal VECH and dynamic conditional correlation (DCC) are applied and 25 GCM predictors were selected for a bivariate temperature heteroscedastic modeling. It is observed that the conditional covariance between predictors and temperature is not very strong and mostly depends on the interaction between the random process governing temporal variation of predictors and predictants. The DCC model reveals a time varying conditional correlation between GCM predictors and temperature time series. No remarkable increasing or decreasing change is observed for correlation coefficients between GCM predictors and observed temperature during 1980-2000 while weak winter-summer seasonality is clear for both conditional covariance and correlation. Furthermore, the stationarity and nonlinearity Kwiatkowski-Phillips-Schmidt-Shin (KPSS) and Brock-Dechert-Scheinkman (BDS) tests showed that GCM predictors, temperature and their conditional correlation time series are nonlinear but stationary during 1980-2000 according to BDS and KPSS test results. However, the degree of nonlinearity of temperature time series is higher than most of the GCM predictors.

  16. 20 CFR 411.321 - Under what conditions will SSA terminate an agreement with an EN due to inadequate performance?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Under what conditions will SSA terminate an agreement with an EN due to inadequate performance? 411.321 Section 411.321 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Networks § 411.321...

  17. 20 CFR 411.321 - Under what conditions will SSA terminate an agreement with an EN due to inadequate performance?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Under what conditions will SSA terminate an agreement with an EN due to inadequate performance? 411.321 Section 411.321 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Networks § 411.321...

  18. 20 CFR 411.321 - Under what conditions will SSA terminate an agreement with an EN due to inadequate performance?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Under what conditions will SSA terminate an agreement with an EN due to inadequate performance? 411.321 Section 411.321 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Networks § 411.321...

  19. 20 CFR 411.321 - Under what conditions will SSA terminate an agreement with an EN due to inadequate performance?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Under what conditions will SSA terminate an agreement with an EN due to inadequate performance? 411.321 Section 411.321 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Networks § 411.321...

  20. 20 CFR 411.321 - Under what conditions will SSA terminate an agreement with an EN due to inadequate performance?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Under what conditions will SSA terminate an agreement with an EN due to inadequate performance? 411.321 Section 411.321 Employees' Benefits SOCIAL... relating to beneficiaries achieving self-supporting employment and leaving the benefit rolls....

  1. 49 CFR 219.11 - General conditions for chemical tests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false General conditions for chemical tests. 219.11 Section 219.11 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... for chemical tests. (a) Any employee who performs covered service for a railroad is deemed to...

  2. 49 CFR 219.11 - General conditions for chemical tests.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false General conditions for chemical tests. 219.11 Section 219.11 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... for chemical tests. (a) Any employee who performs covered service for a railroad is deemed to...

  3. 49 CFR 219.11 - General conditions for chemical tests.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false General conditions for chemical tests. 219.11 Section 219.11 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... for chemical tests. (a) Any employee who performs covered service for a railroad is deemed to...

  4. 49 CFR 219.11 - General conditions for chemical tests.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false General conditions for chemical tests. 219.11 Section 219.11 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... for chemical tests. (a) Any employee who performs covered service for a railroad is deemed to...

  5. 49 CFR 219.11 - General conditions for chemical tests.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false General conditions for chemical tests. 219.11 Section 219.11 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... for chemical tests. (a) Any employee who performs covered service for a railroad is deemed to...

  6. Local conditions for the generalized covariant entropy bound

    NASA Astrophysics Data System (ADS)

    Gao, Sijie; Lemos, José P.

    2005-04-01

    A set of sufficient conditions for the generalized covariant entropy bound given by Strominger and Thompson is as follows: Suppose that the entropy of matter can be described by an entropy current sa. Let ka be any null vector along L and s≡-kasa. Then the generalized bound can be derived from the following conditions: (i) s'≤2πTabkakb, where s'=ka∇as and Tab is the stress-energy tensor; (ii) on the initial 2-surface B, s(0)≤-1/4θ(0), where θ is the expansion of ka. We prove that condition (ii) alone can be used to divide a spacetime into two regions: The generalized entropy bound holds for all light sheets residing in the region where s<-1/4θ and fails for those in the region where s>-1/4θ. We check the validity of these conditions in FRW flat universe and a scalar field spacetime. Some apparent violations of the entropy bounds in the two spacetimes are discussed. These holographic bounds are important in the formulation of the holographic principle.

  7. PRESENT CONDITION AND MEASURES TO EXPAND OF VOLUNTARY AGREEMENT ON PLASTIC SHOPPING BAGS REDUCTION AT THE PREFECTURAL LEVEL

    NASA Astrophysics Data System (ADS)

    Mori, Mayuka; Kanaya, Ken

    Purpose of this research is to clear present condition and measures to expand of voluntary agreement on plastic shopping bags reduction at the prefectural level. Methods of this research are questionnaire survey to prefectures implementing the agreement and survey by i town page to the number of stores of companies and the number of companies in the prefectures. Findings of this research are as follows: 1. The refusal rate of plastic shopping bags was 10-40% before the implementation of voluntary agreements. And the rate is approximately 70-90% after the implementation. Therefore, before and after the implementation of voluntary agreements, the refusal rate of plastic shopping bags is approximately 40-70% less. 2. It is suggested that the time and number of meetings from proposal to conclusion of the agreement are related in some way, to the ratio of stores participating. On the participation of administration, the ratio of stores participating in the case in which prefecture and cities participate is higher than in the case in which prefecture participates.

  8. Analytical solutions with Generalized Impedance Boundary Conditions (GIBC)

    NASA Technical Reports Server (NTRS)

    Syed, H. H.; Volakis, John L.

    1991-01-01

    Rigorous uniform geometrical theory of diffraction (UTD) diffraction coefficients are presented for a coated convex cylinder simulated with generalized impedance boundary conditions. In particular, ray solutions are obtained which remain valid in the transition region and reduce uniformly to those in the deep lit and shadow regions. These involve new transition functions in place of the usual Fock-type integrals, characteristics to the impedance cylinder. A uniform asymptotic solution is also presented for observations in the close vicinity of the cylinder. The diffraction coefficients for the convex cylinder are obtained via a generalization of the corresponding ones for the circular cylinder.

  9. Rényi generalizations of the conditional quantum mutual information

    SciTech Connect

    Berta, Mario; Seshadreesan, Kaushik P.; Wilde, Mark M.

    2015-02-15

    The conditional quantum mutual information I(A; B|C) of a tripartite state ρ{sub ABC} is an information quantity which lies at the center of many problems in quantum information theory. Three of its main properties are that it is non-negative for any tripartite state, that it decreases under local operations applied to systems A and B, and that it obeys the duality relation I(A; B|C) = I(A; B|D) for a four-party pure state on systems ABCD. The conditional mutual information also underlies the squashed entanglement, an entanglement measure that satisfies all of the axioms desired for an entanglement measure. As such, it has been an open question to find Rényi generalizations of the conditional mutual information, that would allow for a deeper understanding of the original quantity and find applications beyond the traditional memoryless setting of quantum information theory. The present paper addresses this question, by defining different α-Rényi generalizations I{sub α}(A; B|C) of the conditional mutual information, some of which we can prove converge to the conditional mutual information in the limit α → 1. Furthermore, we prove that many of these generalizations satisfy non-negativity, duality, and monotonicity with respect to local operations on one of the systems A or B (with it being left as an open question to prove that monotonicity holds with respect to local operations on both systems). The quantities defined here should find applications in quantum information theory and perhaps even in other areas of physics, but we leave this for future work. We also state a conjecture regarding the monotonicity of the Rényi conditional mutual informations defined here with respect to the Rényi parameter α. We prove that this conjecture is true in some special cases and when α is in a neighborhood of one.

  10. Attractive and repulsive Casimir vacuum energy with general boundary conditions

    NASA Astrophysics Data System (ADS)

    Asorey, M.; Muñoz-Castañeda, J. M.

    2013-09-01

    The infrared behaviour of quantum field theories confined in bounded domains is strongly dependent on the shape and structure of space boundaries. The most significant physical effect arises in the behaviour of the vacuum energy. The Casimir energy can be attractive or repulsive depending on the nature of the boundary. We calculate the vacuum energy for a massless scalar field confined between two homogeneous parallel plates with the most general type of boundary conditions depending on four parameters. The analysis provides a powerful method to identify which boundary conditions generate attractive or repulsive Casimir forces between the plates. In the interface between both regimes we find a very interesting family of boundary conditions which do not induce any type of Casimir force. We also show that the attractive regime holds far beyond identical boundary conditions for the two plates required by the Kenneth-Klich theorem and that the strongest attractive Casimir force appears for periodic boundary conditions whereas the strongest repulsive Casimir force corresponds to anti-periodic boundary conditions. Most of the analysed boundary conditions are new and some of them can be physically implemented with metamaterials.

  11. Categories, Concepts, and Conditioning: How Humans Generalize Fear

    PubMed Central

    Dunsmoor, Joseph E.; Murphy, Gregory L.

    2015-01-01

    During the past century, Pavlovian conditioning has served as the predominant experimental paradigm and theoretical framework to understand how humans learn to fear and avoid real or perceived dangers. Animal models for translational research offer insight into basic behavioral and neurophysiological factors mediating the acquisition, expression, inhibition, and generalization of fear. However, it is important to consider the limits of traditional animal models when applied to humans. Here, we focus on the question of how humans generalize fear. We propose that to understand fear generalization in humans requires taking into account research on higher-level cognition such as category-based induction, inferential reasoning, and representation of conceptual knowledge. Doing so will open the door for productive avenues of new research. PMID:25577706

  12. Categories, concepts, and conditioning: how humans generalize fear.

    PubMed

    Dunsmoor, Joseph E; Murphy, Gregory L

    2015-02-01

    During the past century, Pavlovian conditioning has served as the predominant experimental paradigm and theoretical framework to understand how humans learn to fear and avoid real or perceived dangers. Animal models for translational research offer insight into basic behavioral and neurophysiological factors mediating the acquisition, expression, inhibition, and generalization of fear. However, it is important to consider the limits of traditional animal models when applied to humans. Here, we focus on the question of how humans generalize fear. We propose that to understand fear generalization in humans requires taking into account research on higher-level cognition such as category-based induction, inferential reasoning, and representation of conceptual knowledge. Doing so will open the door for productive avenues of new research.

  13. Agreement Between Self-Report and Medical Record Prevalence of 16 Chronic Conditions in the Alaska EARTH Study.

    PubMed

    Koller, Kathryn R; Wilson, Amy S; Asay, Elvin D; Metzger, Jesse S; Neal, Diane E

    2014-07-01

    The gold standard for health information is the health record. Hospitalization and outpatient diagnoses provide health systems with data on which to project health costs and plan programmatic changes. Although health record information may be reliable and perceived as accurate, it may not include population-specific information and may exclude care provided outside a specific health care facility. Sole reliance on medical record information may lead to underutilization of health care services and inadequate assessment of population health status. In this study, we analyzed agreement, without assuming a gold standard, between self-reported and recorded chronic conditions in an American Indian/Alaska Native cohort. Self-reported health history was collected from 3821 adult participants of the Alaska EARTH study during 2004-2006. Participant medical records were electronically accessed and reviewed. Self-reported chronic conditions were underreported in relation to the medical record and both information sources reported the absence more reliably than the presence of conditions (across conditions, median positive predictive value = 64%, median negative predictive value = 94%). Agreement was affected by age, gender, and education. Differences between participant- and provider-based prevalence of chronic conditions demonstrate why health care administrators and policy makers should not rely exclusively on medical record-based administrative data for a comprehensive evaluation of population health.

  14. Agreement Between Self-Report and Medical Record Prevalence of 16 Chronic Conditions in the Alaska EARTH Study.

    PubMed

    Koller, Kathryn R; Wilson, Amy S; Asay, Elvin D; Metzger, Jesse S; Neal, Diane E

    2014-07-01

    The gold standard for health information is the health record. Hospitalization and outpatient diagnoses provide health systems with data on which to project health costs and plan programmatic changes. Although health record information may be reliable and perceived as accurate, it may not include population-specific information and may exclude care provided outside a specific health care facility. Sole reliance on medical record information may lead to underutilization of health care services and inadequate assessment of population health status. In this study, we analyzed agreement, without assuming a gold standard, between self-reported and recorded chronic conditions in an American Indian/Alaska Native cohort. Self-reported health history was collected from 3821 adult participants of the Alaska EARTH study during 2004-2006. Participant medical records were electronically accessed and reviewed. Self-reported chronic conditions were underreported in relation to the medical record and both information sources reported the absence more reliably than the presence of conditions (across conditions, median positive predictive value = 64%, median negative predictive value = 94%). Agreement was affected by age, gender, and education. Differences between participant- and provider-based prevalence of chronic conditions demonstrate why health care administrators and policy makers should not rely exclusively on medical record-based administrative data for a comprehensive evaluation of population health. PMID:24399443

  15. Agreement between Descriptive and Experimental Analyses of Behavior under Naturalistic Test Conditions

    ERIC Educational Resources Information Center

    Martens, Brian K.; Gertz, Lynne E.; Werder, Candace Susan de Lacy; Rymanowski, Jennifer L.

    2010-01-01

    We compared the results of a contingency space analysis (CSA) of behavior-consequence recordings to the results of functional analysis (FA) test conditions involving antecedent stimuli and verbal statements that both differed from and mimicked those in the natural environment. Three preschool children with autism spectrum disorder participated.…

  16. Neural correlates of valence generalization in an affective conditioning paradigm.

    PubMed

    Schick, Anita; Adam, Ruth; Vollmayr, Barbara; Kuehner, Christine; Kanske, Philipp; Wessa, Michèle

    2015-10-01

    In case of uncertainty, predictions that are based on prior, similar experiences guide our decision by processes of generalization. Over-generalization of negative information has been identified as an important feature of several psychopathologies, including anxiety disorders and depression, and might underlie biased interpretation of ambiguous information. Here, we investigated the neural correlates of valence generalization to ambiguous stimuli using a translational affective conditioning task during fMRI. Twenty-five healthy individuals participated in a conditioning procedure with (1) an initial acquisition phase, where participants learned the positive and negative valence of two different tones (reference tones) through their responses and subsequent feedback and (2) a test phase, where participants were presented with the previously learned reference tones and three additional tones with intermediate frequency to the learned reference tones. By recording the responses to these intermediate stimuli we were able to assess the participantsí interpretation of ambiguous tones as either positive or negative. Behavioral results revealed a graded response pattern to the three intermediate tones, which was mirrored on the neural level. More specifically, parametric analyses OF BOLD responses to all five tones revealed a linear effect in bilateral anterior insula and SMA with lowest activation to the negative reference tone and highest activation to the positive negative tone. In addition, a cluster in the SMA showed a reverse-quadratic response, i.e., the strongest response for the most ambiguous tone. These findings suggest overlapping regions in the salience network that mediate valence generalization and decision-making under ambiguity, potentially underlying biased ambiguous cue interpretation. PMID:26057359

  17. Most general AdS3 boundary conditions

    NASA Astrophysics Data System (ADS)

    Grumiller, Daniel; Riegler, Max

    2016-10-01

    We consider the most general asymptotically anti-de Sitter boundary conditions in three-dimensional Einstein gravity with negative cosmological constant. The metric contains in total twelve independent functions, six of which are interpreted as chemical potentials (or non-normalizable fluctuations) and the other half as canonical boundary charges (or normalizable fluctuations). Their presence modifies the usual Fefferman-Graham expansion. The asymptotic symmetry algebra consists of two sl{(2)}_k current algebras, the levels of which are given by k = ℓ/(4 G N ), where ℓ is the AdS radius and G N the three-dimensional Newton constant.

  18. Sufficient conditions for thermal rectification in general graded materials.

    PubMed

    Pereira, Emmanuel

    2011-03-01

    We address a fundamental problem for the advance of phononics: the search of a feasible thermal diode. We establish sufficient conditions for the existence of thermal rectification in general graded materials. By starting from simple assumptions satisfied by the usual anharmonic models that describe heat conduction in solids, we derive an expression for the rectification. The analytical formula shows how to increase the rectification, and the conditions to avoid its decay with the system size, a problem present in the recurrent model of diodes given by the sequential coupling of two or three different parts. Moreover, for these graded systems, we show that the regimes of nondecaying rectification and of normal conductivity do not overlap. Our results indicate the graded systems as optimal materials for a thermal diode, the basic component of several devices of phononics.

  19. Asymptotic boundary conditions for dissipative waves: General theory

    NASA Technical Reports Server (NTRS)

    Hagstrom, Thomas

    1990-01-01

    An outstanding issue in the computational analysis of time dependent problems is the imposition of appropriate radiation boundary conditions at artificial boundaries. Accurate conditions are developed which are based on the asymptotic analysis of wave propagation over long ranges. Employing the method of steepest descents, dominant wave groups are identified and simple approximations to the dispersion relation are considered in order to derive local boundary operators. The existence of a small number of dominant wave groups may be expected for systems with dissipation. Estimates of the error as a function of domain size are derived under general hypotheses, leading to convergence results. Some practical aspects of the numerical construction of the asymptotic boundary operators are also discussed.

  20. Invalidity of the quantitative adiabatic condition and general conditions for adiabatic approximations

    NASA Astrophysics Data System (ADS)

    Li, Dafa

    2016-05-01

    The adiabatic theorem was proposed about 90 years ago and has played an important role in quantum physics. The quantitative adiabatic condition constructed from eigenstates and eigenvalues of a Hamiltonian is a traditional tool to estimate adiabaticity and has proven to be the necessary and sufficient condition for adiabaticity. However, recently the condition has become a controversial subject. In this paper, we list some expressions to estimate the validity of the adiabatic approximation. We show that the quantitative adiabatic condition is invalid for the adiabatic approximation via the Euclidean distance between the adiabatic state and the evolution state. Furthermore, we deduce general necessary and sufficient conditions for the validity of the adiabatic approximation by different definitions.

  1. Analytical solutions with Generalized Impedance Boundary Conditions (GIBC)

    NASA Technical Reports Server (NTRS)

    Ricoy, Mark A.; Volakis, John L.

    1990-01-01

    The diffraction by a material discontinuity in a thick dielectric/ferrite layer is considered by modeling the layer as a distributed current sheet obeying generalized sheet transition conditions (GSTC's). The sheet currents are then formulated and solved via the standard dual integral equation approach. This yields the diffracted field in terms of unknown constants which underscore the non-uniqueness of the GSTC current sheet representation. The constants are dependent on the geometry and properties of the discontinuity and are determined by enforcing field continuity across the material junction. This requires the field internal to the slab which are determined from the external ones via analytic continuity. Results are given which validate the solution and demonstrate the importance of the constants.

  2. Study on plate silencer with general boundary conditions

    NASA Astrophysics Data System (ADS)

    Liu, Gongmin; Zhao, Xiaochen; Zhang, Wenping; Li, Shuaijun

    2014-09-01

    A plate silencer consists of an expansion chamber with two side-branch rigid cavities covered by plates. Previous studies showed that, in a duct, the introduction of simply supported or clamped plates into an air conveying system could achieve broadband quieting from low to medium frequencies. In this study, analytical formulation is extended to the plate silencer with general boundary conditions. A set of static beam functions, which are a combination of sine series and third-order polynomial, is employed as the trial functions of the plate vibration velocity. Greens function and Kirchhoff-Helmholtz integral are used to solve the sound radiation in the duct and the cavity, and then the vibration velocity of the plate is obtained. Having obtained the vibration velocity, the pressure perturbations induced by the plate oscillation and the transmission loss are found. Optimization is carried out in order to obtain the widest stopband. The transmission loss calculated by the analytical method agrees closely with the result of the finite element method simulation. Further studies with regard to the plate under several different classical boundary conditions based on the validated model show that a clamped-free plate silencer has the worst stopband. Attempts to release the boundary restriction of the plate are also made to study its effect on sound reflection. Results show that a softer end for a clamped-clamped plate silencer helps increase the optimal bandwidth, while the same treatment for simply supported plate silencer will result in performance degradation.

  3. Grades and Withdrawal Rates in Cell Biology and Genetics Based upon Institution Type for General Biology and Implications for Transfer Articulation Agreements

    ERIC Educational Resources Information Center

    Regier, Kimberly Fayette

    2016-01-01

    General biology courses (for majors) are often transferred from one institution to another. These courses must prepare students for upper division courses in biology. In Colorado, a Biology Transfer Articulation Agreement that includes general biology has been created across the state. An evaluation was conducted of course grades in two upper…

  4. 32 CFR 37.1100 - What are my responsibilities generally as an administrative agreements officer for a TIA?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... permission to sell or exclusively license intellectual property to entities that do not agree to manufacture... agreement, as described in 32 CFR 22.715. Responsibilities for TIAs include: (a) Advising agreements... discussed in § 37.1105(c). (e) Coordinating audit requests and reviewing audit reports for both...

  5. 32 CFR 37.1100 - What are my responsibilities generally as an administrative agreements officer for a TIA?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... permission to sell or exclusively license intellectual property to entities that do not agree to manufacture... agreement, as described in 32 CFR 22.715. Responsibilities for TIAs include: (a) Advising agreements... discussed in § 37.1105(c). (e) Coordinating audit requests and reviewing audit reports for both...

  6. 32 CFR 37.1100 - What are my responsibilities generally as an administrative agreements officer for a TIA?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... permission to sell or exclusively license intellectual property to entities that do not agree to manufacture... agreement, as described in 32 CFR 22.715. Responsibilities for TIAs include: (a) Advising agreements... discussed in § 37.1105(c). (e) Coordinating audit requests and reviewing audit reports for both...

  7. 32 CFR 37.1100 - What are my responsibilities generally as an administrative agreements officer for a TIA?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... agreement, as described in 32 CFR 22.715. Responsibilities for TIAs include: (a) Advising agreements... substantial involvement in the research project. This may involve attendance with program officials at kickoff... discussed in § 37.1105(c). (e) Coordinating audit requests and reviewing audit reports for both...

  8. 45 CFR 1180.48 - General conditions on publications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... THE ARTS AND THE HUMANITIES INSTITUTE OF MUSEUM AND LIBRARY SERVICES GRANTS REGULATIONS General... developed in whole or in part under a grant from the Institute of Museum and Library Services. However,...

  9. Generalized conditioned reinforcement with pigeons in a token economy.

    PubMed

    DeFulio, Anthony; Yankelevitz, Rachelle; Bullock, Christopher; Hackenberg, Timothy D

    2014-07-01

    Six pigeons were studied in a token economy in which tokens could be produced and exchanged for food on one side of an experimental chamber and for water on the opposite side of the chamber. Responses on one key produced tokens according to a token-production fixed ratio (FR) schedule. Responses on a second key produced an exchange period during which tokens were exchanged for water or food. In Experiment 1a, food tokens could be earned and exchanged under restricted food budgets, and water tokens could be earned and exchanged under water restricted budgets. In Experiment 1b, a third (generalized) token type could be earned and exchanged for either food or water under water restricted budgets. Across Experiments 1a and 1b, the number of tokens accumulated prior to exchange increased as the exchange-production schedule was increased. In Experiment 1b, pigeons produced more generalized than specific tokens, suggesting enhanced reinforcing efficacy of generalized tokens. In Experiment 2, the FR token-production price was manipulated under water restriction and then under food restriction. Production of each token type generally declined as a function of its own price and increased as a function of the price of the alternate type, demonstrating own-price and cross-price elasticity. Production of food and water tokens often changed together, indicating complementarity. Production of specific and generalized tokens changed in opposite directions, indicating substitutability. This is the first demonstration of sustained generalized functions of tokens in nonhumans, and illustrates a promising method for exploring economic contingencies in a controlled environment. PMID:24979723

  10. Generalized conditioned reinforcement with pigeons in a token economy.

    PubMed

    DeFulio, Anthony; Yankelevitz, Rachelle; Bullock, Christopher; Hackenberg, Timothy D

    2014-07-01

    Six pigeons were studied in a token economy in which tokens could be produced and exchanged for food on one side of an experimental chamber and for water on the opposite side of the chamber. Responses on one key produced tokens according to a token-production fixed ratio (FR) schedule. Responses on a second key produced an exchange period during which tokens were exchanged for water or food. In Experiment 1a, food tokens could be earned and exchanged under restricted food budgets, and water tokens could be earned and exchanged under water restricted budgets. In Experiment 1b, a third (generalized) token type could be earned and exchanged for either food or water under water restricted budgets. Across Experiments 1a and 1b, the number of tokens accumulated prior to exchange increased as the exchange-production schedule was increased. In Experiment 1b, pigeons produced more generalized than specific tokens, suggesting enhanced reinforcing efficacy of generalized tokens. In Experiment 2, the FR token-production price was manipulated under water restriction and then under food restriction. Production of each token type generally declined as a function of its own price and increased as a function of the price of the alternate type, demonstrating own-price and cross-price elasticity. Production of food and water tokens often changed together, indicating complementarity. Production of specific and generalized tokens changed in opposite directions, indicating substitutability. This is the first demonstration of sustained generalized functions of tokens in nonhumans, and illustrates a promising method for exploring economic contingencies in a controlled environment.

  11. 36 CFR 79.8 - Terms and conditions to include in contracts, memoranda and agreements for curatorial services.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... regulations 43 CFR part 7, 36 CFR part 296, 18 CFR part 1312, and 32 CFR part 229; (g) The term of the contract, memorandum or agreement; and procedures for modification, suspension, extension, and termination; (h) A statement of costs associated with the contract, memorandum or agreement; the funds or...

  12. Analytical performance, agreement and user-friendliness of six point-of-care testing urine analysers for urinary tract infection in general practice

    PubMed Central

    Schot, Marjolein J C; van Delft, Sanne; Kooijman-Buiting, Antoinette M J; de Wit, Niek J; Hopstaken, Rogier M

    2015-01-01

    Objective Various point-of-care testing (POCT) urine analysers are commercially available for routine urine analysis in general practice. The present study compares analytical performance, agreement and user-friendliness of six different POCT urine analysers for diagnosing urinary tract infection in general practice. Setting All testing procedures were performed at a diagnostic centre for primary care in the Netherlands. Urine samples were collected at four general practices. Primary and secondary outcome measures Analytical performance and agreement of the POCT analysers regarding nitrite, leucocytes and erythrocytes, with the laboratory reference standard, was the primary outcome measure, and analysed by calculating sensitivity, specificity, positive and negative predictive value, and Cohen's κ coefficient for agreement. Secondary outcome measures were the user-friendliness of the POCT analysers, in addition to other characteristics of the analysers. Results The following six POCT analysers were evaluated: Uryxxon Relax (Macherey Nagel), Urisys 1100 (Roche), Clinitek Status (Siemens), Aution 11 (Menarini), Aution Micro (Menarini) and Urilyzer (Analyticon). Analytical performance was good for all analysers. Compared with laboratory reference standards, overall agreement was good, but differed per parameter and per analyser. Concerning the nitrite test, the most important test for clinical practice, all but one showed perfect agreement with the laboratory standard. For leucocytes and erythrocytes specificity was high, but sensitivity was considerably lower. Agreement for leucocytes varied between good to very good, and for the erythrocyte test between fair and good. First-time users indicated that the analysers were easy to use. They expected higher productivity and accuracy when using these analysers in daily practice. Conclusions The overall performance and user-friendliness of all six commercially available POCT urine analysers was sufficient to justify routine

  13. 7 CFR 272.1 - General terms and conditions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the Social Security Act in order to assist in the administration of that program, and employees of the... benefits under titles II and XVI of the Social Security Act; (v) Employees of the Comptroller General's... Federal law enforcement officers, upon written request, for the purpose of obtaining the address,...

  14. 7 CFR 272.1 - General terms and conditions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... the Social Security Act in order to assist in the administration of that program, and employees of the... benefits under titles II and XVI of the Social Security Act; (v) Employees of the Comptroller General's... Federal law enforcement officers, upon written request, for the purpose of obtaining the address,...

  15. 7 CFR 272.1 - General terms and conditions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the Social Security Act in order to assist in the administration of that program, and employees of the... benefits under titles II and XVI of the Social Security Act; (v) Employees of the Comptroller General's... Federal law enforcement officers, upon written request, for the purpose of obtaining the address,...

  16. 7 CFR 272.1 - General terms and conditions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... the Social Security Act in order to assist in the administration of that program, and employees of the... benefits under titles II and XVI of the Social Security Act; (v) Employees of the Comptroller General's... Federal law enforcement officers, upon written request, for the purpose of obtaining the address,...

  17. 7 CFR 272.1 - General terms and conditions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the Social Security Act in order to assist in the administration of that program, and employees of the... benefits under titles II and XVI of the Social Security Act; (v) Employees of the Comptroller General's... Federal law enforcement officers, upon written request, for the purpose of obtaining the address,...

  18. Higher Education Crossing Borders. A Guide to the Implications of the General Agreement on Trade in Services (GATS) for Cross-Border Education

    ERIC Educational Resources Information Center

    Knight, Jane

    2006-01-01

    This Guide examines the different dimensions of cross-border education within the context of General Agreement on Trade in Services (GATS): the present landscape, opportunities and challenges and the implications for policy and practice in higher education. It is meant for a range of stakeholders: policymakers, senior academic leaders, faculty…

  19. Terms and Conditions of Employment in Collective Bargaining Agreements Negotiated by School Boards and Teachers Associations in Pennsylvania School Districts for 2012-2013

    ERIC Educational Resources Information Center

    Dismuke, Daniel P.

    2013-01-01

    The purpose of this study was to identify and describe the typical terms and conditions of employment in 2012-2013 negotiated agreements in Pennsylvania school districts, and to determine if there was a relationship between enrollment size and 5 selected terms and conditions of employment: base salary; highest salary; teacher contribution for one…

  20. General rule for boundary conditions from the action principle

    NASA Astrophysics Data System (ADS)

    Steiner, Roee

    2016-03-01

    We construct models where initial and boundary conditions can be found from the fundamental rules of physics, without the need to assume them, they will be derived from the action principle. Those constraints are established from physical viewpoint, and it is not in the form of Lagrange multipliers. We show some examples from the past and some new examples that can be useful, where constraint can be obtained from the action principle. Those actions represent physical models. We show that it is possible to use our rule to get those constraints directly.

  1. 77 FR 42677 - Special Conditions: General Electric CT7-2E1 Turboshaft Engine

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-20

    ... Federal Aviation Administration 14 CFR Part 33 Special Conditions: General Electric CT7-2E1 Turboshaft.... SUMMARY: This action proposes special conditions for the General Electric CT7-2E1 engine model. This.... Background On September 10, 2009, General Electric applied for an amendment to type certificate E8NE to...

  2. Breaking generalized covariance, classical renormalization, and boundary conditions from superpotentials

    NASA Astrophysics Data System (ADS)

    Livshits, Gideon I.

    2014-02-01

    Superpotentials offer a direct means of calculating conserved charges associated with the asymptotic symmetries of space-time. Yet superpotentials have been plagued with inconsistencies, resulting in nonphysical or incongruent values for the mass, angular momentum, and energy loss due to radiation. The approach of Regge and Teitelboim, aimed at a clear Hamiltonian formulation with a boundary, and its extension to the Lagrangian formulation by Julia and Silva have resolved these issues, and have resulted in a consistent, well-defined and unique variational equation for the superpotential, thereby placing it on a firm footing. A hallmark solution of this equation is the KBL superpotential obtained from the first-order Lovelock Lagrangian. Nevertheless, here we show that these formulations are still insufficient for Lovelock Lagrangians of higher orders. We present a paradox, whereby the choice of fields affects the superpotential for equivalent on-shell dynamics. We offer two solutions to this paradox: either the original Lagrangian must be effectively renormalized, or that boundary conditions must be imposed, so that space-time be asymptotically maximally symmetric. Non-metricity is central to this paradox, and we show how quadratic non-metricity in the bulk of space-time contributes to the conserved charges on the boundary, where it vanishes identically. This is a realization of the gravitational Higgs mechanism, proposed by Percacci, where the non-metricity is the analogue of the Goldstone boson.

  3. 41 CFR 302-3.514 - Under what conditions must we pay for tour renewal agreement travel?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... must we pay for tour renewal agreement travel? 302-3.514 Section 302-3.514 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES RELOCATION ALLOWANCES 3-RELOCATION ALLOWANCE BY SPECIFIC TYPE Agency Responsibilities Overseas Tour Renewal Travel § 302-3.514...

  4. 41 CFR 302-3.514 - Under what conditions must we pay for tour renewal agreement travel?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... must we pay for tour renewal agreement travel? 302-3.514 Section 302-3.514 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES RELOCATION ALLOWANCES 3-RELOCATION ALLOWANCE BY SPECIFIC TYPE Agency Responsibilities Overseas Tour Renewal Travel § 302-3.514...

  5. Second Language Acquisition of Gender Agreement in Explicit and Implicit Training Conditions: An Event-Related Potential Study

    ERIC Educational Resources Information Center

    Morgan-Short, Kara; Sanz, Cristina; Steinhauer, Karsten; Ullman, Michael T.

    2010-01-01

    This study employed an artificial language learning paradigm together with a combined behavioral/event-related potential (ERP) approach to examine the neurocognition of the processing of gender agreement, an aspect of inflectional morphology that is problematic in adult second language (L2) learning. Subjects learned to speak and comprehend an…

  6. District Self-Assessment Tool: For Modification of Collective Bargaining Agreements to Achieve Flexible Conditions for School Turnaround

    ERIC Educational Resources Information Center

    Mass Insight Education (NJ1), 2011

    2011-01-01

    The District Self-Assessment Tool is designed to support districts, unions and Lead Partners, when analyzing their existing collective bargaining agreement (CBA) with the intention of making targeted modifications to support the implementation of dramatic reform in the district's lowest-performing schools. By outlining objectives and suggested…

  7. General Considerations of the Electrostatic Boundary Conditions in Oxide Heterostructures

    SciTech Connect

    Higuchi, Takuya

    2011-08-19

    When the size of materials is comparable to the characteristic length scale of their physical properties, novel functionalities can emerge. For semiconductors, this is exemplified by the 'superlattice' concept of Esaki and Tsu, where the width of the repeated stacking of different semiconductors is comparable to the 'size' of the electrons, resulting in novel confined states now routinely used in opto-electronics. For metals, a good example is magnetic/non-magnetic multilayer films that are thinner than the spin-scattering length, from which giant magnetoresistance (GMR) emerged, used in the read heads of hard disk drives. For transition metal oxides, a similar research program is currently underway, broadly motivated by the vast array of physical properties that they host. This long-standing notion has been recently invigorated by the development of atomic-scale growth and probe techniques, which enables the study of complex oxide heterostructures approaching the precision idealized in Fig. 1(a). Taking the subset of oxides derived from the perovskite crystal structure, the close lattice match across many transition metal oxides presents the opportunity, in principle, to develop a 'universal' heteroepitaxial materials system. Hand-in-hand with the continual improvements in materials control, an increasingly relevant challenge is to understand the consequences of the electrostatic boundary conditions which arise in these structures. The essence of this issue can be seen in Fig. 1(b), where the charge sequence of the sublayer 'stacks' for various representative perovskites is shown in the ionic limit, in the (001) direction. To truly 'universally' incorporate different properties using different materials components, be it magnetism, ferroelectricity, superconductivity, etc., it is necessary to access and join different charge sequences, labelled here in analogy to the designations 'group IV, III-V, II-VI' for semiconductors. As we will review, interfaces between

  8. 20 CFR 633.305 - General benefits and working conditions for program participants.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., DEPARTMENT OF LABOR MIGRANT AND SEASONAL FARMWORKER PROGRAMS Program Design and Administrative Procedures § 633.305 General benefits and working conditions for program participants. (a) Payments for...

  9. Interobserver Agreement between On-Call Radiology Resident and General Radiologist Interpretations of CT Pulmonary Angiograms and CT Venograms

    PubMed Central

    Tamjeedi, Bahar; Correa, José; Semionov, Alexandre; Mesurolle, Benoît

    2015-01-01

    Objectives To evaluate the interobserver agreement (IOA) between the initial radiology resident and the final staff radiologist reports of combined computed tomographic pulmonary angiograms (CTPA) and computed tomographic venograms (CTV) performed during on-call hours. Materials and Methods Approval by the institutional review board was obtained. Six-hundred and ninety-six consecutive studies (CTPA or CTPA with CTV) performed during on-call hours and interpreted by 30 residents were identified. Radiology residents’ reports were compared to the final staff reports. Three tests outcomes were considered (positive, P; negative, N; indeterminate, I). Discordant cases were reviews by a chest radiologist. Results CTPAs were reported by staff radiologists as positive for pulmonary embolism (PE) in 18% (126/694), with a kappa of 0.81 (95% CI 0.77-0.86) with 3 outcomes (P, N, I), and a kappa of 0.89 (95% CI 0.85-0.94) with 2 outcomes (P, N). Regarding PE location, good concordance was observed for positive studies, with a kappa of 0.86 (95% CI 0.78 – 0.95). CTVs were reported as positive by staff radiologists in 8.5% (33/388), with a kappa of 0.66 (95% CI 0.55-0.77) with 3 outcomes (P, N, I), and a kappa of 0.89 (95% CI 0.8-1.0) with 2 outcomes (P, N). The IOA between residents and staff radiologists increased with increasing residency year level for CTPAs, but did not for CTVs. Conclusions Very good and good IOA were observed between resident and staff radiologist interpretations for CTPA and CTV, respectively, with tendency towards improved IOA as residency level of training increased for CTPA, but not for CTV. PMID:25938666

  10. Processing of FRG high-temperature gas-cooled reactor fuel elements at General Atomic under the US/FRG cooperative agreement for spent fuel elements

    SciTech Connect

    Holder, N.D.; Strand, J.B.; Schwarz, F.A.; Drake, R.N.

    1981-11-01

    The Federal Republic of Germany (FRG) and the United States (US) are cooperating on certain aspects of gas-cooled reactor technology under an umbrella agreement. Under the spent fuel treatment development section of the agreement, both FRG mixed uranium/ thorium and low-enriched uranium fuel spheres have been processed in the Department of Energy-sponsored cold pilot plant for high-temperature gas-cooled reactor (HTGR) fuel processing at General Atomic Company in San Diego, California. The FRG fuel spheres were crushed and burned to recover coated fuel particles suitable for further treatment for uranium recovery. Successful completion of the tests described in this paper demonstrated certain modifications to the US HTGR fuel burining process necessary for FRG fuel treatment. Results of the tests will be used in the design of a US/FRG joint prototype headend facility for HTGR fuel.

  11. Framingham Ten-Year General Cardiovascular Disease Risk: Agreement between BMI-Based and Cholesterol-Based Estimates in a South Asian Convenience Sample

    PubMed Central

    Jones, Charlotte A.; Ross, Leanne; Surani, Nadia; Dharamshi, Narissa; Karmali, Karima

    2015-01-01

    The goal of this analysis was to determine the agreement between body mass index-based and cholesterol-based ten-year Framingham general cardiovascular disease risk scores among a convenience sample of 773 South Asian Canadian adults attending community-based screening clinics. Scores were calculated using age, systolic blood pressure, antihypertensive use, current smoking, diabetes, and total cholesterol and high density lipoprotein (for cholesterol-based risk) or height and weight (for body mass index-based risk). Mean risk score differences (body mass index-based risk minus cholesterol-based risk) were estimated using paired t-tests. Bland-Altman plots were used to assess agreement between scores. Finally, agreement across risk categories (low [<10%], moderate [10% to <20%], high [> = 20%]) was examined using the kappa statistic. Average agreement between the two risk scores was quite good overall (mean differences of 0.6% for men and 0.5% for women), but increased to about 3% among participants 60–74 years of age. However, Bland-Altman plots revealed that the differences between the two scores and the variability of the differences increased with increasing average 10-year risk. In terms of clinical importance, the limits of agreement were reasonable for women < 60 years (95% confidence interval: -3.2% to 3.1%), but of concern for women 60-74 years (95% confidence interval: -6.0% to 12.3%), men < 60 years (95% confidence interval: -7.1% to 7.3%) and men 6-074 years (95% confidence interval: -13.8% to 18.8%). Agreement across categories was moderate for most sex and age groups examined (kappa values: 0.51 for women < 60 years, 0.50 for women 60-74 years, 0.65 for men < 60 years), except for men 60-74 years, where agreement was only fair (kappa = 0.26). In light of these disagreements, evaluation of a participant’s change in cardiovascular disease risk over time will necessitate use of the same risk score (i.e., either body mass index-based or cholesterol

  12. The Impact of Instructions on Generalization of Conditioned Fear in Humans.

    PubMed

    Ahmed, Ola; Lovibond, Peter F

    2015-09-01

    Generalization of conditioned fear has been implicated in the maintenance and proliferation of fear in anxiety disorders. The role of cognitive processes in generalization of conditioning is an important yet understudied issue. Vervliet et al. (2010) tested generalization of fear to a visual stimulus of a particular color and shape paired with electric shock. Test stimuli shared either the color or shape of the CS+. Prior to conditioning, participants were instructed that either color or shape would be predictive of shock. Generalization was stronger to the stimulus containing the instructed feature, suggesting that instructions impacted generalization of fear. However, the result may also reflect the impact of instructions on attention and learning during the conditioning phase. In the present study, the instructional manipulation was given after the conditioning phase to control for any impact of instructions on learning. A similar result to that reported by Vervliet et al. was observed. On self-reported expectancy of shock, generalization was greater to the test stimulus that included the instructed stimulus feature. The same pattern was observed on skin conductance, although it did not reach statistical significance. The findings indicate that explicitly instructed information affected generalization of conditioned fear independently of any impact on learning, pointing to the role of cognitive processes in human fear generalization. They also support the utility of cognitive therapy approaches, which are employed after fear has already developed, in addressing clinical overgeneralization. PMID:26459840

  13. The Impact of Instructions on Generalization of Conditioned Fear in Humans.

    PubMed

    Ahmed, Ola; Lovibond, Peter F

    2015-09-01

    Generalization of conditioned fear has been implicated in the maintenance and proliferation of fear in anxiety disorders. The role of cognitive processes in generalization of conditioning is an important yet understudied issue. Vervliet et al. (2010) tested generalization of fear to a visual stimulus of a particular color and shape paired with electric shock. Test stimuli shared either the color or shape of the CS+. Prior to conditioning, participants were instructed that either color or shape would be predictive of shock. Generalization was stronger to the stimulus containing the instructed feature, suggesting that instructions impacted generalization of fear. However, the result may also reflect the impact of instructions on attention and learning during the conditioning phase. In the present study, the instructional manipulation was given after the conditioning phase to control for any impact of instructions on learning. A similar result to that reported by Vervliet et al. was observed. On self-reported expectancy of shock, generalization was greater to the test stimulus that included the instructed stimulus feature. The same pattern was observed on skin conductance, although it did not reach statistical significance. The findings indicate that explicitly instructed information affected generalization of conditioned fear independently of any impact on learning, pointing to the role of cognitive processes in human fear generalization. They also support the utility of cognitive therapy approaches, which are employed after fear has already developed, in addressing clinical overgeneralization.

  14. 36 CFR 79.8 - Terms and conditions to include in contracts, memoranda and agreements for curatorial services.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... regulations 43 CFR part 7, 36 CFR part 296, 18 CFR part 1312, and 32 CFR part 229; (g) The term of the... conditions for making the collection available for scientific, educational and religious uses, including... methods for conducting and documenting the inspections and inventories stipulated in § 79.11 of this...

  15. 36 CFR 79.8 - Terms and conditions to include in contracts, memoranda and agreements for curatorial services.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... regulations 43 CFR part 7, 36 CFR part 296, 18 CFR part 1312, and 32 CFR part 229; (g) The term of the... conditions for making the collection available for scientific, educational and religious uses, including... methods for conducting and documenting the inspections and inventories stipulated in § 79.11 of this...

  16. 36 CFR 79.8 - Terms and conditions to include in contracts, memoranda and agreements for curatorial services.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... regulations 43 CFR part 7, 36 CFR part 296, 18 CFR part 1312, and 32 CFR part 229; (g) The term of the... conditions for making the collection available for scientific, educational and religious uses, including... methods for conducting and documenting the inspections and inventories stipulated in § 79.11 of this...

  17. On the Ideal Boundary Condition in a General Toroidal Geometry for a Mixed Magnetic Field Representation

    SciTech Connect

    X. Z. Tang

    2000-12-18

    Subtleties of implementing the standard perfectly conducting wall boundary condition in a general toroidal geometry are clarified for a mixed scalar magnetic field representation. An iterative scheme based on Ohm's law is given.

  18. Application of generalized separation of variables to solving mixed problems with irregular boundary conditions

    NASA Astrophysics Data System (ADS)

    Gasymov, E. A.; Guseinova, A. O.; Gasanova, U. N.

    2016-07-01

    One of the methods for solving mixed problems is the classical separation of variables (the Fourier method). If the boundary conditions of the mixed problem are irregular, this method, generally speaking, is not applicable. In the present paper, a generalized separation of variables and a way of application of this method to solving some mixed problems with irregular boundary conditions are proposed. Analytical representation of the solution to this irregular mixed problem is obtained.

  19. Relating different quantum generalizations of the conditional Rényi entropy

    SciTech Connect

    Tomamichel, Marco; Berta, Mario; Hayashi, Masahito

    2014-08-15

    Recently a new quantum generalization of the Rényi divergence and the corresponding conditional Rényi entropies was proposed. Here, we report on a surprising relation between conditional Rényi entropies based on this new generalization and conditional Rényi entropies based on the quantum relative Rényi entropy that was used in previous literature. Our result generalizes the well-known duality relation H(A|B) + H(A|C) = 0 of the conditional von Neumann entropy for tripartite pure states to Rényi entropies of two different kinds. As a direct application, we prove a collection of inequalities that relate different conditional Rényi entropies and derive a new entropic uncertainty relation.

  20. 40 CFR 86.408-78 - General standards; increase in emissions; unsafe conditions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... ENGINES Emission Regulations for 1978 and Later New Motorcycles, General Provisions § 86.408-78 General... motorcycle to enable such vehicle to conform to standards imposed by this subpart: (1) Shall not in its... condition endangering the motorcycle, its rider(s), or persons or property in close proximity to the...

  1. 40 CFR 86.408-78 - General standards; increase in emissions; unsafe conditions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ENGINES Emission Regulations for 1978 and Later New Motorcycles, General Provisions § 86.408-78 General... motorcycle to enable such vehicle to conform to standards imposed by this subpart: (1) Shall not in its... condition endangering the motorcycle, its rider(s), or persons or property in close proximity to the...

  2. 40 CFR 86.408-78 - General standards; increase in emissions; unsafe conditions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... ENGINES Emission Regulations for 1978 and Later New Motorcycles, General Provisions § 86.408-78 General... motorcycle to enable such vehicle to conform to standards imposed by this subpart: (1) Shall not in its... condition endangering the motorcycle, its rider(s), or persons or property in close proximity to the...

  3. 40 CFR 86.408-78 - General standards; increase in emissions; unsafe conditions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... ENGINES Emission Regulations for 1978 and Later New Motorcycles, General Provisions § 86.408-78 General... motorcycle to enable such vehicle to conform to standards imposed by this subpart: (1) Shall not in its... condition endangering the motorcycle, its rider(s), or persons or property in close proximity to the...

  4. 40 CFR 86.408-78 - General standards; increase in emissions; unsafe conditions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ENGINES Emission Regulations for 1978 and Later New Motorcycles, General Provisions § 86.408-78 General... motorcycle to enable such vehicle to conform to standards imposed by this subpart: (1) Shall not in its... condition endangering the motorcycle, its rider(s), or persons or property in close proximity to the...

  5. Activation of dopamine neurons is critical for aversive conditioning and prevention of generalized anxiety.

    PubMed

    Zweifel, Larry S; Fadok, Jonathan P; Argilli, Emmanuela; Garelick, Michael G; Jones, Graham L; Dickerson, Tavis M K; Allen, James M; Mizumori, Sheri J Y; Bonci, Antonello; Palmiter, Richard D

    2011-05-01

    Generalized anxiety is thought to result, in part, from impairments in contingency awareness during conditioning to cues that predict aversive or fearful outcomes. Dopamine neurons of the ventral midbrain exhibit heterogeneous responses to aversive stimuli that are thought to provide a critical modulatory signal to facilitate orientation to environmental changes and assignment of motivational value to unexpected events. Here we describe a mouse model in which activation of dopamine neurons in response to an aversive stimulus is attenuated by conditional genetic inactivation of functional NMDA receptors on dopamine neurons. We discovered that altering the magnitude of excitatory responses by dopamine neurons in response to an aversive stimulus was associated with impaired conditioning to a cue that predicts an aversive outcome. Impaired conditioning by these mice was associated with the development of a persistent, generalized anxiety-like phenotype. These data are consistent with a role for dopamine in facilitating contingency awareness that is critical for the prevention of generalized anxiety.

  6. Conditional discrimination in mentally retarded adults: the development of generalized skills.

    PubMed Central

    Saunders, K J; Spradlin, J E

    1990-01-01

    The development of generalized conditional discrimination skills was examined in adults with retardation. Two subjects with histories of failure to acquire arbitrary matching under trial-and-error procedures were successful under procedures that trained one or more prerequisite skills. The successive discrimination between the sample stimuli was established by training the subjects to name the stimuli. The simultaneous discrimination between the comparison stimuli was established using either (a) standard simple discrimination training with reversals or (b) a procedure in which each of the two sample-comparison relations in the conditional discrimination was presented in blocks of trials, with the size of the blocks decreasing gradually until sample presentation was randomized. The amount of prerequisite training required varied across subjects and across successive conditional discriminations. After acquiring either two or three conditional discriminations with component training, both subjects learned new conditional discriminations under trial-and-error procedures. In general, each successive conditional discrimination was acquired more rapidly. Tests showed that conditional responding had become a generalized skill. Symmetry was shown for almost all trained relations. Symmetry trial samples were ultimately named the same as the stimuli to which they were related in training. PMID:2103584

  7. Developmental aspects of fear: Comparing the acquisition and generalization of conditioned fear in children and adults

    PubMed Central

    Schiele, Miriam A.; Reinhard, Julia; Reif, Andreas; Domschke, Katharina; Romanos, Marcel; Deckert, Jürgen

    2016-01-01

    ABSTRACT Most research on human fear conditioning and its generalization has focused on adults whereas only little is known about these processes in children. Direct comparisons between child and adult populations are needed to determine developmental risk markers of fear and anxiety. We compared 267 children and 285 adults in a differential fear conditioning paradigm and generalization test. Skin conductance responses (SCR) and ratings of valence and arousal were obtained to indicate fear learning. Both groups displayed robust and similar differential conditioning on subjective and physiological levels. However, children showed heightened fear generalization compared to adults as indexed by higher arousal ratings and SCR to the generalization stimuli. Results indicate overgeneralization of conditioned fear as a developmental correlate of fear learning. The developmental change from a shallow to a steeper generalization gradient is likely related to the maturation of brain structures that modulate efficient discrimination between danger and (ambiguous) safety cues. © 2016 The Authors. Developmental Psychobiology Published by Wiley Periodicals, Inc. Dev Psychobiol 58: 471–481, 2016. PMID:26798984

  8. Student's Research Work as the Condition of Continuity of General and Professional Education

    ERIC Educational Resources Information Center

    Vedishenkova, Marina V.; Efimova, Elena V.; Ryabova, Ekaterina V.

    2015-01-01

    The problem in question is necessitated by the contradictions between requirements of successive educational process of general and professional education and the absence of new mechanisms of providing the continuity of education which is effective under modern conditions. The aim of the article in question is to provide the potential of the…

  9. Preservation Conditions, Practices, and Needs in the General Libraries. A Report by the Preservation Committee.

    ERIC Educational Resources Information Center

    Texas Univ., Austin. General Libraries.

    The survey documented in this report was conducted in 1981 to investigate the preservation conditions, practices, and needs of the units of the University of Texas at Austin General Libraries. The report is divided into six major portions. The first five sections report the responses to questionnaires on specific formats: books and serials;…

  10. 10 CFR 72.212 - Conditions of general license issued under § 72.210.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Conditions of general license issued under § 72.210. 72.212 Section 72.212 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER...

  11. 10 CFR 72.212 - Conditions of general license issued under § 72.210.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Conditions of general license issued under § 72.210. 72.212 Section 72.212 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER...

  12. 10 CFR 72.212 - Conditions of general license issued under § 72.210.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Conditions of general license issued under § 72.210. 72.212 Section 72.212 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER...

  13. 38 CFR 1.576 - General policies, conditions of disclosure, accounting of certain disclosures, and definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false General policies, conditions of disclosure, accounting of certain disclosures, and definitions. 1.576 Section 1.576 Pensions... (including the Executive Office of the President), or any independent regulatory agency. (2) The...

  14. Generalization of Conditioned Fear along a Dimension of Increasing Fear Intensity

    ERIC Educational Resources Information Center

    Dunsmoor, Joseph E.; Mitroff, Stephen R.; LaBar, Kevin S.

    2009-01-01

    The present study investigated the extent to which fear generalization in humans is determined by the amount of fear intensity in nonconditioned stimuli relative to a perceptually similar conditioned stimulus. Stimuli consisted of graded emotionally expressive faces of the same identity morphed between neutral and fearful endpoints. Two…

  15. 42 CFR 84.99 - Man tests; testing conditions; general requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Man tests; testing conditions; general requirements. 84.99 Section 84.99 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus §...

  16. 42 CFR 84.99 - Man tests; testing conditions; general requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Man tests; testing conditions; general requirements. 84.99 Section 84.99 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus §...

  17. 42 CFR 84.99 - Man tests; testing conditions; general requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Man tests; testing conditions; general requirements. 84.99 Section 84.99 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus §...

  18. 42 CFR 84.99 - Man tests; testing conditions; general requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Man tests; testing conditions; general requirements. 84.99 Section 84.99 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus §...

  19. 42 CFR 84.99 - Man tests; testing conditions; general requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Man tests; testing conditions; general requirements. 84.99 Section 84.99 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus §...

  20. Fear generalization in humans: impact of feature learning on conditioning and extinction.

    PubMed

    Vervliet, Bram; Geens, Maarten

    2014-09-01

    Little is known about the role of discrete stimulus features in the regulation of fear. This study examined the effects of feature learning on the acquisition and extinction of fear conditioning. Human participants were fear conditioned to a yellow triangle (CS+) using an electrical shock. We manipulated feature learning through differential conditioning. The nonconditioned control stimulus (CS-) was a red triangle in one group (Color-Relevant), but a yellow circle in the other group (Shape-Relevant). Next, two generalization stimuli were tested that shared the shape- or color-feature with the CS+ (a blue triangle and a yellow square). Online shock-expectancy ratings and skin conductance responding showed that the CS- determined the pattern of fear generalization: the same-color stimulus elicited more fear in Group Color-Relevant, versus the same-shape stimulus in group Shape-Relevant. Furthermore, extinguishing these two generalization stimuli had no detectable effect on fear of the CS+. These results show that fear generalization is influenced by feature learning through differential conditioning, and that exposures to different features of a stimulus are not sufficient to extinguish fear of that stimulus as a whole.

  1. Extended slow-roll conditions and primordial fluctuations: multiple scalar fields and generalized gravity

    SciTech Connect

    Chiba, Takeshi; Yamaguchi, Masahide E-mail: gucci@phys.aoyama.ac.jp

    2009-01-15

    As an extension of our previous study, we derive slow-roll conditions for multiple scalar fields which are non-minimally coupled with gravity and for generalized gravity theories of the form f({phi}, R). We provide simple formulae of the spectral indices of scalar/tensor perturbations in terms of the slow-roll parameters.

  2. The General Necessary Condition for the Validity of Dirac's Transition Perturbation Theory

    NASA Technical Reports Server (NTRS)

    Quang, Nguyen Vinh

    1996-01-01

    For the first time, from the natural requirements for the successive approximation the general necessary condition of validity of the Dirac's method is explicitly established. It is proved that the conception of 'the transition probability per unit time' is not valid. The 'super-platinium rules' for calculating the transition probability are derived for the arbitrarily strong time-independent perturbation case.

  3. No effect of trait anxiety on differential fear conditioning or fear generalization.

    PubMed

    Torrents-Rodas, David; Fullana, Miquel A; Bonillo, Albert; Caseras, Xavier; Andión, Oscar; Torrubia, Rafael

    2013-02-01

    Previous studies have shown that individuals with anxiety disorders exhibit deficits in fear inhibition and excessive generalization of fear, but little data exist on individuals at risk from these disorders. The present study examined the role of trait anxiety in the acquisition and generalization of fear in 126 healthy participants selected on the basis of their trait-anxiety scores. Measures of conditioning included fear-potentiated startle, skin conductance response and online risk ratings for the unconditioned stimulus. Contrary to our hypotheses, trait anxiety did not have any effect either on the acquisition or the generalization of fear. Our results suggest that these fear conditioning processes are not impaired in individuals at risk from anxiety. PMID:23131617

  4. Generalization of turbojet and turbine-propeller engine performance in windmilling condition

    NASA Technical Reports Server (NTRS)

    Wallner, Ewis E; Welna, Henry J

    1951-01-01

    Windmilling characteristics of several turbojet and turbine-propeller engines were investigated individually over a wide range of flight conditions in the NACA Lewis altitude wind tunnel. A study was made of all these data and windmilling performance of gas turbine engines was generalized. Although internal-drag, air-flow, and total-pressure-drop parameters were generalized to a single curve for both the axial-flow type engines and another for the centrifugal-flow engine. The engine speed, component pressure changes, and windmilling-propeller drag were generalized to single curves for the two turbine-propeller-type engines investigated. By the use of these curves the windmilling performance can be estimated for axial-flow type gas turbine engines similar to the types investigated over a wide range of flight conditions.

  5. Graphicality conditions for general scale-free complex networks and their application to visibility graphs.

    PubMed

    Rodríguez, Miguel A

    2016-07-01

    We obtain graphicality conditions for general types of scale-free networks. The same conditions obtained for uncorrelated networks are obtained in the general case. Then an upper bound relating γ, the exponent of the degree distribution, with the cutoff exponent κ, as κ<1/γ is established. This bound is valid for all networks with a well-defined power-law degree distribution in the range γ≤2. Some recent numerical research on visibility networks arising from persistent fractional Brownian motion (fBm) processes are reviewed since they do not fulfill these conditions. As a consequence, a new relationship between the exponent γ of the degree distribution and the Hurst exponent H of the fBm process, γ⪅1/H, is postulated.

  6. Vibration analysis and transient response of a functionally graded piezoelectric curved beam with general boundary conditions

    NASA Astrophysics Data System (ADS)

    Su, Zhu; Jin, Guoyong; Ye, Tiangui

    2016-06-01

    The paper presents a unified solution for free and transient vibration analyses of a functionally graded piezoelectric curved beam with general boundary conditions within the framework of Timoshenko beam theory. The formulation is derived by means of the variational principle in conjunction with a modified Fourier series which consists of standard Fourier cosine series and supplemented functions. The mechanical and electrical properties of functionally graded piezoelectric materials (FGPMs) are assumed to vary continuously in the thickness direction and are estimated by Voigt’s rule of mixture. The convergence, accuracy and reliability of the present formulation are demonstrated by comparing the present solutions with those from the literature and finite element analysis. Numerous results for FGPM beams with different boundary conditions, geometrical parameters as well as material distributions are given. Moreover, forced vibration of the FGPM beams subjected to dynamic loads and general boundary conditions are also investigated.

  7. Graphicality conditions for general scale-free complex networks and their application to visibility graphs

    NASA Astrophysics Data System (ADS)

    Rodríguez, Miguel A.

    2016-07-01

    We obtain graphicality conditions for general types of scale-free networks. The same conditions obtained for uncorrelated networks are obtained in the general case. Then an upper bound relating γ , the exponent of the degree distribution, with the cutoff exponent κ , as κ <1 /γ is established. This bound is valid for all networks with a well-defined power-law degree distribution in the range γ ≤2 . Some recent numerical research on visibility networks arising from persistent fractional Brownian motion (fBm) processes are reviewed since they do not fulfill these conditions. As a consequence, a new relationship between the exponent γ of the degree distribution and the Hurst exponent H of the fBm process, γ ⪅1 /H , is postulated.

  8. Graphicality conditions for general scale-free complex networks and their application to visibility graphs.

    PubMed

    Rodríguez, Miguel A

    2016-07-01

    We obtain graphicality conditions for general types of scale-free networks. The same conditions obtained for uncorrelated networks are obtained in the general case. Then an upper bound relating γ, the exponent of the degree distribution, with the cutoff exponent κ, as κ<1/γ is established. This bound is valid for all networks with a well-defined power-law degree distribution in the range γ≤2. Some recent numerical research on visibility networks arising from persistent fractional Brownian motion (fBm) processes are reviewed since they do not fulfill these conditions. As a consequence, a new relationship between the exponent γ of the degree distribution and the Hurst exponent H of the fBm process, γ⪅1/H, is postulated. PMID:27575155

  9. Hybrid preconditioning for iterative diagonalization of ill-conditioned generalized eigenvalue problems in electronic structure calculations

    SciTech Connect

    Cai, Yunfeng; Bai, Zhaojun; Pask, John E.; Sukumar, N.

    2013-12-15

    The iterative diagonalization of a sequence of large ill-conditioned generalized eigenvalue problems is a computational bottleneck in quantum mechanical methods employing a nonorthogonal basis for ab initio electronic structure calculations. We propose a hybrid preconditioning scheme to effectively combine global and locally accelerated preconditioners for rapid iterative diagonalization of such eigenvalue problems. In partition-of-unity finite-element (PUFE) pseudopotential density-functional calculations, employing a nonorthogonal basis, we show that the hybrid preconditioned block steepest descent method is a cost-effective eigensolver, outperforming current state-of-the-art global preconditioning schemes, and comparably efficient for the ill-conditioned generalized eigenvalue problems produced by PUFE as the locally optimal block preconditioned conjugate-gradient method for the well-conditioned standard eigenvalue problems produced by planewave methods.

  10. Proving the achronal averaged null energy condition from the generalized second law

    SciTech Connect

    Wall, Aron C.

    2010-01-15

    A null line is a complete achronal null geodesic. It is proven that for any quantum fields minimally coupled to semiclassical Einstein gravity, the averaged null energy condition (ANEC) on null lines is a consequence of the generalized second law of thermodynamics for causal horizons. This result is shown to leading order in Planck's constant for perturbations to classical backgrounds satisfying the null energy condition. Auxiliary assumptions include CPT and the existence of a suitable renormalization scheme for the generalized entropy. Although the ANEC can be violated on general geodesics in curved spacetimes, as long as the ANEC holds on null lines there exist theorems showing that semiclassical gravity should satisfy positivity of energy, topological censorship, and should not admit closed timelike curves. It is pointed out that these theorems fail once the linearized graviton field is quantized, because then the renormalized shear-squared term in the Raychaudhuri equation can be negative. A 'shear-inclusive' generalization of the ANEC is proposed to remedy this, and is proven under an additional assumption about perturbations to horizons in classical general relativity.

  11. General conditions for proximity induced odd-frequency superconductivity in two-dimensional electronic systems

    NASA Astrophysics Data System (ADS)

    Rossi, Enrico; Triola, Christopher; Badiane, Driss; Balatsky, Alexander V.

    We obtain the general conditions for the emergence of odd-frequency superconducting pairing in a two-dimensional (2D) electronic system proximity-coupled to a superconductor, making minimal assumptions about both the 2D system and the superconductor. Using our general results we show that a simple heterostructure formed by a monolayer of a group VI transition metal dichalcogenide, such as molybdenum disulfide, and an s-wave superconductor with Rashba spin-orbit coupling will exhibit odd-frequency superconducting pairing. Work supported by US DOE BES E304, KAW, ACS-PRF-53581-DNI5, and NSF-DMR-1455233.

  12. General Conditions for Proximity-Induced Odd-Frequency Superconductivity in Two-Dimensional Electronic Systems.

    PubMed

    Triola, Christopher; Badiane, Driss M; Balatsky, Alexander V; Rossi, E

    2016-06-24

    We obtain the general conditions for the emergence of odd-frequency superconducting pairing in a two-dimensional (2D) electronic system proximity coupled to a superconductor, making minimal assumptions about both the 2D system and the superconductor. Using our general results we show that a simple heterostructure formed by a monolayer of a group VI transition metal dichalcogenide, such as molybdenum disulfide, and an s-wave superconductor with Rashba spin-orbit coupling exhibits odd-frequency superconducting pairing. Our results allow the identification of a new class of systems among van der Waals heterostructures in which odd-frequency superconductivity should be present. PMID:27391743

  13. 12 CFR 1806.300 - Award Agreement; sanctions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Award Agreement; sanctions. 1806.300 Section 1806.300 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY BANK ENTERPRISE AWARD PROGRAM Terms and Conditions of Assistance § 1806.300 Award Agreement; sanctions. (a) General. After the Fund selects...

  14. Laplace asymptotic expansions of conditional Wiener integrals and generalized Mehler kernel formulas

    NASA Astrophysics Data System (ADS)

    Davies, Ian; Truman, Aubrey

    1982-11-01

    Imitating Schilder's results for Wiener integrals rigorous Laplace asymptotic expansions are proven for conditional Wiener integrals. Applications are given for deriving generalized Mehler kernel formulas, up to arbitrarily high orders in powers of ℏ, for exp{-TH(ℏ)/ℏ}(x, y), T>0 where H(ℏ)=[(-ℏ2/2)Δ1+V], Δ1 being the one-dimensional Laplacian, V being a real-valued potential V∈C∞(R), bounded below, together with its second derivative.

  15. General conditions for scale-invariant perturbations in an expanding universe

    SciTech Connect

    Geshnizjani, Ghazal; Kinney, William H.; Dizgah, Azadeh Moradinezhad E-mail: whkinney@buffalo.edu

    2011-11-01

    We investigate the general properties of expanding cosmological models which generate scale-invariant curvature perturbations in the presence of a variable speed of sound. We show that in an expanding universe, generation of a super-Hubble, nearly scale-invariant spectrum of perturbations over a range of wavelengths consistent with observation requires at least one of three conditions: (1) accelerating expansion, (2) a speed of sound faster than the speed of light, or (3) super-Planckian energy density.

  16. Robust and general method for determining surface fluid flow boundary conditions in articular cartilage contact mechanics modeling.

    PubMed

    Pawaskar, Sainath Shrikant; Fisher, John; Jin, Zhongmin

    2010-03-01

    Contact detection in cartilage contact mechanics is an important feature of any analytical or computational modeling investigation when the biphasic nature of cartilage and the corresponding tribology are taken into account. The fluid flow boundary conditions will change based on whether the surface is in contact or not, which will affect the interstitial fluid pressurization. This in turn will increase or decrease the load sustained by the fluid phase, with a direct effect on friction, wear, and lubrication. In laboratory experiments or clinical hemiarthroplasty, when a rigid indenter or metallic prosthesis is used to apply load to the cartilage, there will not be any fluid flow normal to the surface in the contact region due to the impermeable nature of the indenter/prosthesis. In the natural joint, on the other hand, where two cartilage surfaces interact, flow will depend on the pressure difference across the interface. Furthermore, in both these cases, the fluid would flow freely in non-contacting regions. However, it should be pointed out that the contact area is generally unknown in advance in both cases and can only be determined as part of the solution. In the present finite element study, a general and robust algorithm was proposed to decide nodes in contact on the cartilage surface and, accordingly, impose the fluid flow boundary conditions. The algorithm was first tested for a rigid indenter against cartilage model. The algorithm worked well for two-dimensional four-noded and eight-noded axisymmetric element models as well as three-dimensional models. It was then extended to include two cartilages in contact. The results were in excellent agreement with the previous studies reported in the literature.

  17. [General functional state (tonus) of the brain and conditioned reflexes as the mechanisms of it's regulation].

    PubMed

    Khananashvili, M M

    2008-01-01

    The article is dedicated to P.S. Kupalov, due to his 120 Anniversary. P.S. Kupalov was the disciple of I.P. Pavlov and his nearest collaborator. Right after I.P. Pavlov, he was at the head of the Institute of Experimental Medicine in St-Petersburg, where he developed a number of new ideas, concerning conditioned reflexes. Thus, he discovered shortened conditioned reflexes--central mechanisms of regulation of general functional state of the brain, and he created, on the base of the studies of unlimited motor activity in animals using his own method of situational conditioned reflexes, the conception of situational conditioned reflexes. P.S. Kupalov found out a number of new explanations for development of experimental neuroses and determined their mechanisms, as well. He was the one among the first disciples of I.P. Pavlov, who indicated at the complex structural-functional organization of conditioned reflexes, and he played the great part for the creation of modern theory about the nature of behavior, based on conditioned reflexes. The most important theses of P.S. Kupalov's conception, which is of great cognitive significance at the moment, as well as some results of the studies by his disciples and followers, developing the ideas of P.S. Kupalov, are presented in the article. PMID:19178077

  18. Bittracker-a bitmap tracker for visual tracking under very general conditions.

    PubMed

    Leichter, Ido; Lindenbaum, Michael; Rivlin, Ehud

    2008-09-01

    This paper addresses the problem of visual tracking under very general conditions: a possibly non-rigid target whose appearance may drastically change over time; general camera motion; a 3D scene; and no a priori information except initialization. This is in contrast to the vast majority of trackers which rely on some limited model in which, for example, the target's appearance is known a priori or restricted, the scene is planar, or a pan tilt zoom camera is used. Their goal is to achieve speed and robustness, but their limited context may cause them to fail in the more general case. The proposed tracker works by approximating, in each frame, a PDF (probability distribution function) of the target's bitmap and then estimating the maximum a posteriori bitmap. The PDF is marginalized over all possible motions per pixel, thus avoiding the stage in which optical flow is determined. This is an advantage over other general-context trackers that do not use the motion cue at all or rely on the error-prone calculation of optical flow. Using a Gibbs distribution with respect to the first-order neighborhood system yields a bitmap PDF whose maximization may be transformed into that of a quadratic pseudo-Boolean function, the maximum of which is approximated via a reduction to a maximum-flow problem. Many experiments were conducted to demonstrate that the tracker is able to track under the aforementioned general context. PMID:18617716

  19. Boundary conditions for General Relativity on AdS3 and the KdV hierarchy

    NASA Astrophysics Data System (ADS)

    Pérez, Alfredo; Tempo, David; Troncoso, Ricardo

    2016-06-01

    It is shown that General Relativity with negative cosmological constant in three spacetime dimensions admits a new family of boundary conditions being labeled by a nonnegative integer k. Gravitational excitations are then described by "boundary gravitons" that fulfill the equations of the k-th element of the KdV hierarchy. In particular, k = 0 corresponds to the Brown-Henneaux boundary conditions so that excitations are described by chiral movers. In the case of k = 1, the boundary gravitons fulfill the KdV equation and the asymptotic symmetry algebra turns out to be infinite-dimensional, abelian and devoid of central extensions. The latter feature also holds for the remaining cases that describe the hierarchy ( k > 1). Our boundary conditions then provide a gravitational dual of two noninteracting left and right KdV movers, and hence, boundary gravitons possess anisotropic Lifshitz scaling with dynamical exponent z = 2 k + 1. Remarkably, despite spacetimes solving the field equations are locally AdS, they possess anisotropic scaling being induced by the choice of boundary conditions. As an application, the entropy of a rotating BTZ black hole is precisely recovered from a suitable generalization of the Cardy formula that is compatible with the anisotropic scaling of the chiral KdV movers at the boundary, in which the energy of AdS spacetime with our boundary conditions depends on z and plays the role of the central charge. The extension of our boundary conditions to the case of higher spin gravity and its link with different classes of integrable systems is also briefly addressed.

  20. Mining Agreements with Indian Tribes

    ERIC Educational Resources Information Center

    Luebben, Tom

    1976-01-01

    The article discusses aspects of negotiating agreements for exploration, development, and mining of hard minerals on Indian Reservations. The agreements discussed are typical of copper agreements, but the general points under discussion are applicable to most hard minerals except for uranium, coal, and oil which are substantially different.…

  1. Generalized adjoint consistent treatment of wall boundary conditions for compressible flows

    NASA Astrophysics Data System (ADS)

    Hartmann, Ralf; Leicht, Tobias

    2015-11-01

    In this article, we revisit the adjoint consistency analysis of Discontinuous Galerkin discretizations of the compressible Euler and Navier-Stokes equations with application to the Reynolds-averaged Navier-Stokes and k- ω turbulence equations. Here, particular emphasis is laid on the discretization of wall boundary conditions. While previously only one specific combination of discretizations of wall boundary conditions and of aerodynamic force coefficients has been shown to give an adjoint consistent discretization, in this article we generalize this analysis and provide a discretization of the force coefficients for any consistent discretization of wall boundary conditions. Furthermore, we demonstrate that a related evaluation of the cp- and cf-distributions is required. The freedom gained in choosing the discretization of boundary conditions without loosing adjoint consistency is used to devise a new adjoint consistent discretization including numerical fluxes on the wall boundary which is more robust than the adjoint consistent discretization known up to now. While this work is presented in the framework of Discontinuous Galerkin discretizations, the insight gained is also applicable to (and thus valuable for) other discretization schemes. In particular, the discretization of integral quantities, like the drag, lift and moment coefficients, as well as the discretization of local quantities at the wall like surface pressure and skin friction should follow as closely as possible the discretization of the flow equations and boundary conditions at the wall boundary.

  2. A general condition for adaptive genetic polymorphism in temporally and spatially heterogeneous environments.

    PubMed

    Svardal, Hannes; Rueffler, Claus; Hermisson, Joachim

    2015-02-01

    Both evolution and ecology have long been concerned with the impact of variable environmental conditions on observed levels of genetic diversity within and between species. We model the evolution of a quantitative trait under selection that fluctuates in space and time, and derive an analytical condition for when these fluctuations promote genetic diversification. As ecological scenario we use a generalized island model with soft selection within patches in which we incorporate generation overlap. We allow for arbitrary fluctuations in the environment including spatio-temporal correlations and any functional form of selection on the trait. Using the concepts of invasion fitness and evolutionary branching, we derive a simple and transparent condition for the adaptive evolution and maintenance of genetic diversity. This condition relates the strength of selection within patches to expectations and variances in the environmental conditions across space and time. Our results unify, clarify, and extend a number of previous results on the evolution and maintenance of genetic variation under fluctuating selection. Individual-based simulations show that our results are independent of the details of the genetic architecture and whether reproduction is clonal or sexual. The onset of increased genetic variance is predicted accurately also in small populations in which alleles can go extinct due to environmental stochasticity.

  3. Boundary conditions and the generalized metric formulation of the double sigma model

    NASA Astrophysics Data System (ADS)

    Ma, Chen-Te

    2015-09-01

    Double sigma model with strong constraints is equivalent to the ordinary sigma model by imposing a self-duality relation. The gauge symmetries are the diffeomorphism and one-form gauge transformation with the strong constraints. We consider boundary conditions in the double sigma model from three ways. The first way is to modify the Dirichlet and Neumann boundary conditions with a fully O (D, D) description from double gauge fields. We perform the one-loop β function for the constant background fields to find low-energy effective theory without using the strong constraints. The low-energy theory can also have O (D, D) invariance as the double sigma model. The second way is to construct different boundary conditions from the projectors. The third way is to combine the antisymmetric background field with field strength to redefine an O (D, D) generalized metric. We use this generalized metric to reconstruct a consistent double sigma model with the classical and quantum equivalence.

  4. Electromagnetic fields and boundary conditions at the interface of generalized transformation media

    SciTech Connect

    Bergamin, Luzi

    2009-12-15

    In this paper, the interface between two transformation media or between a transformation medium and vacuum is studied. Strictly from the transformation optics point of view, the consequences of the boundary conditions at such interfaces are addressed in two different ways. First, we analyze a restricted class of reflectionless interfaces, for which the tools of transformation optics allow to describe the electromagnetic fields on both sides of the interface by means of the same vacuum solution of the Maxwell equations. In a second step, we examine interfaces between two arbitrary transformation media. This analysis is extended to the recently suggested generalization of transformation optics by the author. As a basic application it is shown how the standard law of reflection and refraction at an interface between vacuum and a homogeneous and isotropic medium with arbitrary and independent permittivity and permeability can be understood in a completely geometric way by the use of generalized transformation optics.

  5. Generalization of Pain-Related Fear Using a Left-Right Hand Judgment Conditioning Task.

    PubMed

    Meulders, Ann; Harvie, Daniel S; Lorimer Moseley, G; Vlaeyen, Johan W S

    2015-09-01

    Recent research suggests that the mere intention to perform a painful movement can elicit pain-related fear. Based on these findings, the present study aimed to determine whether imagining a movement that is associated with pain (CS+) can start to elicit conditioned pain-related fear as well and whether pain-related fear elicited by imagining a painful movement can spread towards novel, similar but distinct imagined movements. We proposed a new experimental paradigm that integrates the left-right hand judgment task (HJT) with a differential fear conditioning procedure. During Acquisition, one hand posture (CS+) was consistently followed by a painful electrocutaneous stimulus (pain-US) and another hand posture (CS-) was not. Participants were instructed to make left-right judgments, which involve mentally rotating their own hand to match the displayed hand postures (i.e., motor imagery). During Generalization, participants were presented with a series of novel hand postures with six grades of perceptual similarity to the CS+ (generalization stimuli; GSs). Finally, during Extinction, the CS+ hand posture was no longer reinforced. The results showed that (1) a painful hand posture triggers fear and increased US-expectancy as compared to a nonpainful hand posture, (2) this pain-related fear spreads to similar but distinct hand postures following a generalization gradient, and subsequently, (3) it can be successfully reduced during extinction. These effects were apparent in the verbal ratings, but not in the startle measures. Because of the lack of effect in the startle measures, we cannot draw firm conclusions about whether the "imagined movements" (i.e., motor imagery of the hand postures) gained associative strength rather than the hand posture pictures itself. From a clinical perspective, basic research into generalization of pain-related fear triggered by covert CSs such as intentions, imagined movements and movement-related cognitions might further our

  6. The importance of diet and physical activity in the treatment of conditions managed in general practice.

    PubMed Central

    Little, P; Margetts, B

    1996-01-01

    Evidence from meta-analyses, physiological data and individual studies suggests that diet and exercise are important in the aetiology and treatment of many of the conditions that are managed predominantly in primary care (hypercholesterolaemia, hypertension, diabetes, obesity and excess alcohol intake). However, much of the evidence comes from outside primary care, and it is doubtful whether those studies done in primary care used optimal intervention strategies. A priority for future research should be to demonstrate the feasibility, efficacy and efficiency of lifestyle interventions in a general practice setting. PMID:8731628

  7. Generalized conditional symmetries and related solutions of the Grad-Shafranov equation

    NASA Astrophysics Data System (ADS)

    Cimpoiasu, Rodica

    2014-04-01

    The generalized conditional symmetry (GCS) method is applied to a specific case of the Grad-Shafranov (GS) equation, in cylindrical geometry assuming the existence of an axial symmetry. We investigate the conditions that yield the GS equation admitting a special class of second-order GCSs. The determining system for the unknown arbitrary functions is solved in several special cases and new exact solutions, including solitary waves, different in form and structure from the ones obtained using other nonclassical symmetry methods, are pointed out. Several plots of the level sets or flux surfaces of the new solutions as well as surfaces with vanishing flow are displayed. The obtained solutions can be useful for studying plasma equilibrium, transport phenomena, and magnetohydrodynamic stability.

  8. Generalized conditional symmetries and related solutions of the Grad-Shafranov equation

    SciTech Connect

    Cimpoiasu, Rodica

    2014-04-15

    The generalized conditional symmetry (GCS) method is applied to a specific case of the Grad–Shafranov (GS) equation, in cylindrical geometry assuming the existence of an axial symmetry. We investigate the conditions that yield the GS equation admitting a special class of second-order GCSs. The determining system for the unknown arbitrary functions is solved in several special cases and new exact solutions, including solitary waves, different in form and structure from the ones obtained using other nonclassical symmetry methods, are pointed out. Several plots of the level sets or flux surfaces of the new solutions as well as surfaces with vanishing flow are displayed. The obtained solutions can be useful for studying plasma equilibrium, transport phenomena, and magnetohydrodynamic stability.

  9. 14 CFR 1260.52 - Multiple year grant or cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Multiple year grant or cooperative... GRANTS AND COOPERATIVE AGREEMENTS General Special Conditions § 1260.52 Multiple year grant or cooperative agreement. Multiple Year Grant or Cooperative Agreement October 2000 This is a multiple year grant...

  10. Theoretical results on fractionally integrated exponential generalized autoregressive conditional heteroskedastic processes

    NASA Astrophysics Data System (ADS)

    Lopes, Sílvia R. C.; Prass, Taiane S.

    2014-05-01

    Here we present a theoretical study on the main properties of Fractionally Integrated Exponential Generalized Autoregressive Conditional Heteroskedastic (FIEGARCH) processes. We analyze the conditions for the existence, the invertibility, the stationarity and the ergodicity of these processes. We prove that, if { is a FIEGARCH(p,d,q) process then, under mild conditions, { is an ARFIMA(q,d,0) with correlated innovations, that is, an autoregressive fractionally integrated moving average process. The convergence order for the polynomial coefficients that describes the volatility is presented and results related to the spectral representation and to the covariance structure of both processes { and { are discussed. Expressions for the kurtosis and the asymmetry measures for any stationary FIEGARCH(p,d,q) process are also derived. The h-step ahead forecast for the processes {, { and { are given with their respective mean square error of forecast. The work also presents a Monte Carlo simulation study showing how to generate, estimate and forecast based on six different FIEGARCH models. The forecasting performance of six models belonging to the class of autoregressive conditional heteroskedastic models (namely, ARCH-type models) and radial basis models is compared through an empirical application to Brazilian stock market exchange index.

  11. Analysis of laminated, composite, circular cylindrical shells with general boundary conditions

    NASA Technical Reports Server (NTRS)

    Srinivas, S.

    1974-01-01

    This report develops: (1) a refined approximate theory for the static and dynamic analyses of finite, laminated, composite, circular cylindrical shells with general boundary conditions; (2) an exact three-dimensional analysis of simply supported, laminated, composite, circular cylindrical shells, and (3) a thin-shell theory for laminated, composite, circular cylindrical shells. In the refined approximate theory the displacements are assumed piecewise linear across the thickness and the effects of transverse shear deformations and transverse normal stress are included. A variational approach is followed to obtain the governing differential equations and boundary conditions. A general solution of the governing differential equations is also presented. The results obtained by using the refined approximate theory and the thin-shell theory are compared with the exact results for the case of free vibrations of simply supported, laminated, composite, circular cylindrical shells. The refined approximate theory is very accurate, even for thick shells with short nodal distances, whereas thin-shell theory is reasonably accurate only for thin shells at moderate nodal distances and wave number less than 2.

  12. Closed set of the uniqueness conditions and bifurcation criteria in generalized coupled thermoplasticity for small deformations

    NASA Astrophysics Data System (ADS)

    Śloderbach, Zdzisław

    2016-05-01

    This paper reports the results of a study into global and local conditions of uniqueness and the criteria excluding the possibility of bifurcation of the equilibrium state for small strains. The conditions and criteria are derived on the basis of an analysis of the problem of uniqueness of a solution involving the basic incremental boundary problem of coupled generalized thermo-elasto-plasticity. This work forms a follow-up of previous research (Śloderbach in Bifurcations criteria for equilibrium states in generalized thermoplasticity, IFTR Reports, 1980, Arch Mech 3(35):337-349, 351-367, 1983), but contains a new derivation of global and local criteria excluding a possibility of bifurcation of an equilibrium state regarding a comparison body dependent on the admissible fields of stress rate. The thermal elasto-plastic coupling effects, non-associated laws of plastic flow and influence of plastic strains on thermoplastic properties of a body were taken into account in this work. Thus, the mathematical problem considered here is not a self-conjugated problem.

  13. Iterative generalized synchrosqueezing transform for fault diagnosis of wind turbine planetary gearbox under nonstationary conditions

    NASA Astrophysics Data System (ADS)

    Feng, Zhipeng; Chen, Xiaowang; Liang, Ming

    2015-02-01

    The synchrosqueezing transform can effectively improve the readability of time-frequency representation of mono-component and constant frequency signals. However, for multi-component and time-variant frequency signals, it still suffers from time-frequency blurs. In order to address this issue, the synchrosqueezing transform is improved using iterative generalized demodulation. Firstly, the complex nonstationary signal is decomposed into mono-components of constant frequency by iterative generalized demodulation. Then, the instantaneous frequency of each mono-component is accurately estimated via the synchrosqueezing transform, by exploiting its merit of enhanced time-frequency resolution. Finally, the time-frequency representation of the original signal is obtained by superposing the time-frequency representations of all the mono-components with restored instantaneous frequency. This proposed method generalizes the synchrosqueezing transform to multi-component and time-variant frequency signals, and it has fine time-frequency resolution and is free of cross-term interferences. The proposed method was validated using both numerically simulated and lab experimental vibration signals of planetary gearboxes under nonstationary conditions. The time-variant planetary gearbox characteristic frequencies were effectively identified, and the gear faults were correctly diagnosed.

  14. FFTF Authorization Agreement

    SciTech Connect

    DAUTEL, W.A.

    2000-09-25

    The purpose of the Authorization Agreement is to serve as a mechanism whereby the U.S. Department of Energy, Richland Operations Office (RL) and Fluor Hanford (FH) jointly clarify and agree to key conditions for conducting work safely and efficiently in the Fast Flux Test Facility (FFTF). Work must be accomplished in a manner that achieves high levels of quality while protecting the environment and the safety and health of workers and the public, and complying with applicable contractual and regulatory requirements. It is the intent of this Agreement to address those items of significant importance in establishing and supporting the FFTF Authorization Envelope, but this Agreement in no way alters the terms and conditions of the Project Hanford Management Contract (PHMC), Contract Number DE-AC06-96RL13200.

  15. Lattice Boltzmann method for convection-diffusion equations with general interfacial conditions

    NASA Astrophysics Data System (ADS)

    Hu, Zexi; Huang, Juntao; Yong, Wen-An

    2016-04-01

    In this work, we propose an interfacial scheme accompanying the lattice Boltzmann method for convection-diffusion equations with general interfacial conditions, including conjugate conditions with or without jumps in heat and mass transfer, continuity of macroscopic variables and normal fluxes in ion diffusion in porous media with different porosity, and the Kapitza resistance in heat transfer. The construction of this scheme is based on our boundary schemes [Huang and Yong, J. Comput. Phys. 300, 70 (2015), 10.1016/j.jcp.2015.07.045] for Robin boundary conditions on straight or curved boundaries. It gives second-order accuracy for straight interfaces and first-order accuracy for curved ones. In addition, the new scheme inherits the advantage of the boundary schemes in which only the current lattice nodes are involved. Such an interfacial scheme is highly desirable for problems with complex geometries or in porous media. The interfacial scheme is numerically validated with several examples. The results show the utility of the constructed scheme and very well support our theoretical predications.

  16. The Design of Research Laboratories. Part I: A General Assessment. Part II: Air Conditioning and Conditioned Rooms.

    ERIC Educational Resources Information Center

    Legget, R. F.; Hutcheon, N. B.

    Design factors in the planning of research laboratories are described which include--(1) location, (2) future expansion, (3) internal flexibility, (4) provision of services, (5) laboratory furnishing, (6) internal traffic, (7) space requirements, and (8) building costs. A second part discusses air-conditioning and conditioned rooms--(1)…

  17. A general CFT model for antiferromagnetic spin-1/2 ladders with Mobius boundary conditions

    NASA Astrophysics Data System (ADS)

    Cristofano, Gerardo; Marotta, Vincenzo; Naddeo, Adele; Niccoli, Giuliano

    2008-12-01

    We show how the low energy properties of the two-leg XXZ spin-1/2 ladders with general anisotropy parameter Δ on closed geometries can be accounted for in the framework of the m-reduction procedure developed previously (Cristofano et al 2000 Mod. Phys. Lett. A 15 547; Cristofano et al 2000 Mod. Phys. Lett. A 15 1679; Cristofano et al 2002 Nucl. Phys. B 641 547; Cristofano et al 2004 J. High Energy Phys. JHEP06(2004) 056). In the limit of quasi-decoupled chains, a conformal field theory (CFT) with central charge c = 2 is derived and its ability to describe the model with different boundary conditions is shown. Special emphasis is given to the Mobius boundary conditions which generate a topological defect corresponding to non-trivial single-spinon excitations. Then, in the case of the two-leg XXX ladders we discuss in detail the role of various perturbations in determining the renormalization group flow starting from the ultraviolet (UV) critical point with c = 2.

  18. 13 CFR 107.1800 - Licensee's agreement to terms and conditions in §§ 107.1810 and 107.1820.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... BUSINESS ADMINISTRATION SMALL BUSINESS INVESTMENT COMPANIES Licensee's Noncompliance With Terms of Leverage... violates the terms and conditions of its Leverage is subject to SBA remedies. The terms, conditions...

  19. A generalized sine condition and performance comparison of Wolter type II and Wolter-Schwarzschild extreme ultraviolet telescopes

    NASA Astrophysics Data System (ADS)

    Saha, T. T.

    1984-01-01

    An equation similar to the Abbe sine condition is derived for a Wolter type II telescope. This equation and the sine condition are then combined to produce a so called generalized sine condition. Using the law of reflection, Fermat's principle, the generalized sine condition, and simple geometry the surface equations for a Wolter type II telescope and an equivalent Wolter-Schwarzschild telescope are calculated. The performances of the telescopes are compared in terms of rms blur circle radius at the gaussian focal plane and at best focus.

  20. Conditional Validity of E = mc2 and the Repulsive Gravitation in General Relativity

    NASA Astrophysics Data System (ADS)

    Lo, C. Y.

    Currently, the formula E = mc2 is often misinterpreted as the unconditional equivalence between inertial mass and each type of energy (i.e., m = E/c2). However, according to Einstein's general relativity, such a claim is incorrect. Clearly, a necessary condition for any type of energy (or a combination of many types of energy) to be equivalent to mass is that the combined energy results in a tensor having a non-zero trace. For instance, the energy of photons include the energy of its gravitational wave component as demanded by E = mc2. It is pointed out that the Reissner-Nordstrom metric illustrated that electromagnetic energy and mass are different in terms of gravity. The misinterpretation of E = mc2 being unconditional is responsible for overlooking the repulsive charge-mass interaction. Such an interaction of repulsive gravitation implies that the unification of electromagnetism and gravitation is necessary and correct. Moreover, this analysis shows that both the interpretations of Wilczek and 't Hooft on m = E/c2 being unconditionally true is incorrect.

  1. Generalization of Abel's mechanical problem: The extended isochronicity condition and the superposition principle

    SciTech Connect

    Kinugawa, Tohru

    2014-02-15

    This paper presents a simple but nontrivial generalization of Abel's mechanical problem, based on the extended isochronicity condition and the superposition principle. There are two primary aims. The first one is to reveal the linear relation between the transit-time T and the travel-length X hidden behind the isochronicity problem that is usually discussed in terms of the nonlinear equation of motion (d{sup 2}X)/(dt{sup 2}) +(dU)/(dX) =0 with U(X) being an unknown potential. Second, the isochronicity condition is extended for the possible Abel-transform approach to designing the isochronous trajectories of charged particles in spectrometers and/or accelerators for time-resolving experiments. Our approach is based on the integral formula for the oscillatory motion by Landau and Lifshitz [Mechanics (Pergamon, Oxford, 1976), pp. 27–29]. The same formula is used to treat the non-periodic motion that is driven by U(X). Specifically, this unknown potential is determined by the (linear) Abel transform X(U) ∝ A[T(E)], where X(U) is the inverse function of U(X), A=(1/√(π))∫{sub 0}{sup E}dU/√(E−U) is the so-called Abel operator, and T(E) is the prescribed transit-time for a particle with energy E to spend in the region of interest. Based on this Abel-transform approach, we have introduced the extended isochronicity condition: typically, τ = T{sub A}(E) + T{sub N}(E) where τ is a constant period, T{sub A}(E) is the transit-time in the Abel type [A-type] region spanning X > 0 and T{sub N}(E) is that in the Non-Abel type [N-type] region covering X < 0. As for the A-type region in X > 0, the unknown inverse function X{sub A}(U) is determined from T{sub A}(E) via the Abel-transform relation X{sub A}(U) ∝ A[T{sub A}(E)]. In contrast, the N-type region in X < 0 does not ensure this linear relation: the region is covered with a predetermined potential U{sub N}(X) of some arbitrary choice, not necessarily obeying the Abel-transform relation. In discussing

  2. 14 CFR 303.04 - General rules governing application content, procedure and conditions of approval.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) PROCEDURAL REGULATIONS REVIEW OF AIR CARRIER AGREEMENTS... CFR 302.25. (c) Each page of the application and each document submitted with the application shall be... also indicate the date of preparation and the name and corporate position of the preparer. (d)...

  3. 14 CFR 303.04 - General rules governing application content, procedure and conditions of approval.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) PROCEDURAL REGULATIONS REVIEW OF AIR CARRIER AGREEMENTS... CFR 302.25. (c) Each page of the application and each document submitted with the application shall be... also indicate the date of preparation and the name and corporate position of the preparer. (d)...

  4. 14 CFR 303.04 - General rules governing application content, procedure and conditions of approval.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) PROCEDURAL REGULATIONS REVIEW OF AIR CARRIER AGREEMENTS... CFR 302.25. (c) Each page of the application and each document submitted with the application shall be... also indicate the date of preparation and the name and corporate position of the preparer. (d)...

  5. 14 CFR 303.04 - General rules governing application content, procedure and conditions of approval.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) PROCEDURAL REGULATIONS REVIEW OF AIR CARRIER AGREEMENTS... CFR 302.25. (c) Each page of the application and each document submitted with the application shall be... also indicate the date of preparation and the name and corporate position of the preparer. (d)...

  6. 25 CFR 163.71 - Agreement funding.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Agreement funding. 163.71 Section 163.71 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Cooperative Agreements § 163.71 Agreement funding. In cooperative agreements, the Secretary is authorized to advance...

  7. 25 CFR 163.71 - Agreement funding.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Agreement funding. 163.71 Section 163.71 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Cooperative Agreements § 163.71 Agreement funding. In cooperative agreements, the Secretary is authorized to advance...

  8. 25 CFR 163.71 - Agreement funding.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Agreement funding. 163.71 Section 163.71 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Cooperative Agreements § 163.71 Agreement funding. In cooperative agreements, the Secretary is authorized to advance...

  9. 25 CFR 163.71 - Agreement funding.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Agreement funding. 163.71 Section 163.71 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Cooperative Agreements § 163.71 Agreement funding. In cooperative agreements, the Secretary is authorized to advance...

  10. 25 CFR 163.71 - Agreement funding.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Agreement funding. 163.71 Section 163.71 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Cooperative Agreements § 163.71 Agreement funding. In cooperative agreements, the Secretary is authorized to advance...

  11. Generalized quantum Fokker-Planck equation for photoinduced nonequilibrium processes with positive definiteness condition

    NASA Astrophysics Data System (ADS)

    Jang, Seogjoo

    2016-06-01

    This work provides a detailed derivation of a generalized quantum Fokker-Planck equation (GQFPE) appropriate for photo-induced quantum dynamical processes. The path integral method pioneered by Caldeira and Leggett (CL) [Physica A 121, 587 (1983)] is extended by utilizing a nonequilibrium influence functional applicable to different baths for the ground and the excited electronic states. Both nonequilibrium and non-Markovian effects are accounted for consistently by expanding the paths in the exponents of the influence functional up to the second order with respect to time. This procedure results in approximations involving only single time integrations for the exponents of the influence functional but with additional time dependent boundary terms that have been ignored in previous works. The boundary terms complicate the derivation of a time evolution equation but do not affect position dependent physical observables or the dynamics in the steady state limit. For an effective density operator with the boundary terms factored out, a time evolution equation is derived, through short time expansion of the effective action and Gaussian integration in analytically continued complex domain of space. This leads to a compact form of the GQFPE with time dependent kernels and additional terms, which renders the resulting equation to be in the Dekker form [Phys. Rep. 80, 1 (1981)]. Major terms of the equation are analyzed for the case of Ohmic spectral density with Drude cutoff, which shows that the new GQFPE satisfies the positive definiteness condition in medium to high temperature limit. Steady state limit of the GQFPE is shown to approach the well-known expression derived by CL in the high temperature and Markovian bath limit and also provides additional corrections due to quantum and non-Markovian effects of the bath.

  12. General coalescence conditions for the exact wave functions: Higher-order relations for two-particle systems

    SciTech Connect

    Kurokawa, Yusaku I.; Nakashima, Hiroyuki; Nakatsuji, Hiroshi

    2013-07-28

    We derived the necessary conditions that the non-relativistic time-independent exact wave functions for two-particle systems must satisfy at a coalescence (or cusp) point. Some of such necessary conditions are already known to be Kato's cusp condition (CC) and Rassolov and Chipman's CC. In the present study, we extended and generalized those conditions, calling them generalized coalescence conditions (GCCs). Kato's CC and Rassolov and Chipman's CC were shown to be specific cases included in the GCCs. The GCCs can be applied not only to Coulombic systems but also to any systems where the interaction between two particles is represented in a power series of the inter-particle distance. We confirmed the correctness of our derivation of these GCCs by applying the free complement wave functions of a hydrogen atom in ground and excited states, a harmonic oscillator, and a system with an interacting potential of V=r.

  13. Race and Ethnic Group Differences in Comorbid Major Depressive Disorder, Generalized Anxiety Disorder, and Chronic Medical Conditions.

    PubMed

    Watkins, Daphne C; Assari, Shervin; Johnson-Lawrence, Vicki

    2015-09-01

    This study tested whether race and ethnic group differences exist for lifetime major depressive disorder and/or general anxiety disorder with one or more chronic medical conditions. Data from the National Survey of American Life, which included 3570 African American, 1438 Caribbean Black, and 891 non-Hispanic White adults were analyzed. Outcomes included at least one and multiple chronic medical conditions, from a list of 14 medical conditions (e.g., arthritis, cancer, diabetes, kidney disease, stroke, heart disease, etc.). Logistic regressions were fitted to data to determine how the association between major depressive disorder, general anxiety disorder, and one or more chronic medical conditions vary across race and ethnicity. Lifetime major depressive disorder (but not lifetime general anxiety disorder) was associated with at least one chronic medical condition among African Americans and Caribbean Blacks, but not non-Hispanic Whites. Lifetime major depressive disorder was similarly associated with multiple chronic medical conditions among African Americans, Caribbean Blacks, and non-Hispanic Whites. For Caribbean Blacks, stronger associations were found between major depressive disorder and general anxiety disorder with one or more chronic medical conditions compared to African Americans and non-Hispanic Whites. Findings suggest that race and ethnicity may shape the links between comorbid psychiatric disorders and chronic medical conditions. Mental health screening of individuals with chronic medical conditions in primary health-care settings may benefit from tailoring based on race and ethnicity. More research is needed to understand why associations between physical and mental health vary among race and ethnic groups. PMID:26863467

  14. Race and Ethnic Group Differences in Comorbid Major Depressive Disorder, Generalized Anxiety Disorder, and Chronic Medical Conditions.

    PubMed

    Watkins, Daphne C; Assari, Shervin; Johnson-Lawrence, Vicki

    2015-09-01

    This study tested whether race and ethnic group differences exist for lifetime major depressive disorder and/or general anxiety disorder with one or more chronic medical conditions. Data from the National Survey of American Life, which included 3570 African American, 1438 Caribbean Black, and 891 non-Hispanic White adults were analyzed. Outcomes included at least one and multiple chronic medical conditions, from a list of 14 medical conditions (e.g., arthritis, cancer, diabetes, kidney disease, stroke, heart disease, etc.). Logistic regressions were fitted to data to determine how the association between major depressive disorder, general anxiety disorder, and one or more chronic medical conditions vary across race and ethnicity. Lifetime major depressive disorder (but not lifetime general anxiety disorder) was associated with at least one chronic medical condition among African Americans and Caribbean Blacks, but not non-Hispanic Whites. Lifetime major depressive disorder was similarly associated with multiple chronic medical conditions among African Americans, Caribbean Blacks, and non-Hispanic Whites. For Caribbean Blacks, stronger associations were found between major depressive disorder and general anxiety disorder with one or more chronic medical conditions compared to African Americans and non-Hispanic Whites. Findings suggest that race and ethnicity may shape the links between comorbid psychiatric disorders and chronic medical conditions. Mental health screening of individuals with chronic medical conditions in primary health-care settings may benefit from tailoring based on race and ethnicity. More research is needed to understand why associations between physical and mental health vary among race and ethnic groups.

  15. Pyknoachondrogenesis: an association of skeletal defects resembling achondrogenesis with generalized bone sclerosis. A new condition?

    PubMed

    Camera, G; Giordano, F; Mastroiacovo, P

    1986-10-01

    A stillborn male with skeletal anomalies resembling achondrogenesis with remarkably sclerotic bones is reported. The term "Pyknoachondrogenesis" is suggested for this hitherto undescribed condition. PMID:3791681

  16. General vulnerability to stuttering: The experience of stuttering and conditions bringing about invulnerability.

    PubMed

    Briley, P M; Kalinowski, J S

    2016-08-01

    General vulnerability to stuttering is the broad awareness of stuttering and the ever-present, experiential sense of a person who stutters (PWS). It is defined by stuttering in all its forms and the awareness of its presence, both in moments of stuttering and moments of perceivably fluent speech. Under the heading of general vulnerability to stuttering is specific vulnerability to stuttering, which includes the actual events of stuttering (i.e., overt symptoms, covert symptoms, subperceptual stuttering, and anticipation of stuttering). The differentiation between the two is that specific vulnerability requires a specific moment of stuttering where general vulnerability does not. PMID:27372857

  17. Generalization of verbal conditioning to verbal and nonverbal behavior: group therapy with chronic psychiatric patients1

    PubMed Central

    Tracey, Dorothy A.; Briddell, Dan W.; Wilson, G. Terence

    1974-01-01

    Twelve chronic hospitalized female patients received token reinforcement contingent on two separate classes of verbalizations: (a) positive statements about optional activities available in the hospital setting, and (b) positive statements about people. Cross-class generalization of reinforced verbal responses about activities to overt behavior was tested by actual participation in activities; within-class generalization of verbal responses about people to verbalizations in another stimulus setting was assessed in a structured interview situation. A multiple baseline design with contingency reversals was employed to demonstrate experimental control of both classes of verbalizations in the group sessions. Positive statements about activities generalized to actual participation in activities, while generalization of positive statements about people to verbalization in the extragroup setting did not occur. PMID:4465377

  18. 40 CFR 86.1810-09 - General standards; increase in emissions; unsafe condition; waivers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... conditions and at high altitude conditions, except for supplemental exhaust emission standards, cold.... Cold temperature NMHC emission standards, as described in § 86.1811-10(g), apply only at low altitude....1810-01(f) and (j), and 86.1811-04(e). (2) For vehicles that comply with the cold temperature...

  19. Derivation and application of a class of generalized impedance boundary conditions, part 2

    NASA Technical Reports Server (NTRS)

    Volakis, J. L.; Senior, T. B. A.; Jin, J.-M.

    1989-01-01

    Boundary conditions involving higher order derivatives are presented by simulating surfaces whose reflection coefficients are known analytically, numerically, or experimentally. Procedures for determining the coefficients of the derivatives are discussed, along with the effect of displacing the surface where the boundary conditions are applied. Provided the coefficients satisfy a duality relation, equivalent forms of the boundary conditions involving tangential field components are deduced, and these provide the natural extension to non-planar surfaces. As an illustration, the simulation of metal-backed uniform and three-layer dielectric coatings is given. It is shown that fourth order conditions are capable of providing an accurate simulation for the uniform coating at least a quarter of a wavelength in thickness. Provided, though, some compromise in accuracy is acceptable, it is also shown that a third order condition may be sufficient for practical purposes when simulating uniform coatings.

  20. Effects of hippocampal stimulation on acquisition, extinction and generalization of conditioned suppression in the rat.

    PubMed

    Gustafson, J W; Lidsky, T I; Schwartzbaum, J S

    1975-12-01

    Rats implanted with electrodes in the dorsal or ventral hippocampus received posttrial stimulation in training sessions with footshock reinforcement. Afterdischarges without overt seizures were consistently without effect on the rate of acquisition of suppression of licking during an auditory conditioned stimulus (CS), although conditioning was retarded by the delivery of distracting stimuli following footshock. The rate of conditioning remained insensitive to elicitation of dorsal hippocampal afterdischarges (DHAD) despite subsequent alterations of session length, intertrial interval and preexposure to the CS. However, faster extinction of suppression occurred following DHAD, suggesting a limited but essential role of the hippocampus in addressing stored information.

  1. Pigeons' demand and preference for specific and generalized conditioned reinforcers in a token economy.

    PubMed

    Tan, Lavinia; Hackenberg, Timothy D

    2015-11-01

    Pigeons' demand and preference for specific and generalized tokens was examined in a token economy. Pigeons could produce and exchange different colored tokens for food, for water, or for food or water. Token production was measured across three phases, which examined: (1) across-session price increases (typical demand curve method); (2) within-session price increases (progressive-ratio, PR, schedule); and (3) concurrent pairwise choices between the token types. Exponential demand curves were fitted to the response data and accounted for over 90% total variance. Demand curve parameter values, Pmax , Omax and α showed that demand was ordered in the following way: food tokens, generalized tokens, water tokens, both in Phase 1 and in Phase 3. This suggests that the preferences were predictable on the basis of elasticity and response output from the demand analysis. Pmax and Omax values failed to consistently predict breakpoints and peak response rates in the PR schedules in Phase 2, however, suggesting limits on a unitary conception of reinforcer efficacy. The patterns of generalized token production and exchange in Phase 3 suggest that the generalized tokens served as substitutes for the specific food and water tokens. Taken together, the present findings demonstrate the utility of behavioral economic concepts in the analysis of generalized reinforcement. PMID:26676183

  2. Pigeons' demand and preference for specific and generalized conditioned reinforcers in a token economy.

    PubMed

    Tan, Lavinia; Hackenberg, Timothy D

    2015-11-01

    Pigeons' demand and preference for specific and generalized tokens was examined in a token economy. Pigeons could produce and exchange different colored tokens for food, for water, or for food or water. Token production was measured across three phases, which examined: (1) across-session price increases (typical demand curve method); (2) within-session price increases (progressive-ratio, PR, schedule); and (3) concurrent pairwise choices between the token types. Exponential demand curves were fitted to the response data and accounted for over 90% total variance. Demand curve parameter values, Pmax , Omax and α showed that demand was ordered in the following way: food tokens, generalized tokens, water tokens, both in Phase 1 and in Phase 3. This suggests that the preferences were predictable on the basis of elasticity and response output from the demand analysis. Pmax and Omax values failed to consistently predict breakpoints and peak response rates in the PR schedules in Phase 2, however, suggesting limits on a unitary conception of reinforcer efficacy. The patterns of generalized token production and exchange in Phase 3 suggest that the generalized tokens served as substitutes for the specific food and water tokens. Taken together, the present findings demonstrate the utility of behavioral economic concepts in the analysis of generalized reinforcement.

  3. 47 CFR 3.49 - Agreement to be audited.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Agreement to be audited. 3.49 Section 3.49 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL AUTHORIZATION AND ADMINISTRATION OF ACCOUNTING... be audited. Accounting authorities accept their certifications on condition that they are subject...

  4. 47 CFR 3.49 - Agreement to be audited.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Agreement to be audited. 3.49 Section 3.49 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL AUTHORIZATION AND ADMINISTRATION OF ACCOUNTING... be audited. Accounting authorities accept their certifications on condition that they are subject...

  5. 47 CFR 3.49 - Agreement to be audited.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Agreement to be audited. 3.49 Section 3.49 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL AUTHORIZATION AND ADMINISTRATION OF ACCOUNTING... be audited. Accounting authorities accept their certifications on condition that they are subject...

  6. 47 CFR 3.49 - Agreement to be audited.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Agreement to be audited. 3.49 Section 3.49 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL AUTHORIZATION AND ADMINISTRATION OF ACCOUNTING... be audited. Accounting authorities accept their certifications on condition that they are subject...

  7. Leadership and cooperation at the general medicine department of LMU Munich: Good grades despite difficult conditions

    PubMed Central

    Schelling, Jörg; Braun, Susanne

    2011-01-01

    The relevance of general medicine at German universities will increase over the next few years. Consequently, the discussion of teaching content and even more the improvement of the structures within the still small and dependent departments of general medicine are of major importance. The example of our department at LMU Munich shows which challenges for leadership and cooperation result from lack of financial and personnel structure. The project “cooperation culture” that the department has conducted in collaboration with the LMU Center for Leadership and People Management is presented as a means to promote leadership and cooperation. This project can serve as an inspiration for the coordinators of smaller departments of general medicine at other German universities that are also striving to improve their structure and their position within the university. PMID:22205911

  8. Leadership and cooperation at the general medicine department of LMU Munich: Good grades despite difficult conditions.

    PubMed

    Schelling, Jörg; Braun, Susanne

    2011-01-01

    The relevance of general medicine at German universities will increase over the next few years. Consequently, the discussion of teaching content and even more the improvement of the structures within the still small and dependent departments of general medicine are of major importance. The example of our department at LMU Munich shows which challenges for leadership and cooperation result from lack of financial and personnel structure. The project "cooperation culture" that the department has conducted in collaboration with the LMU Center for Leadership and People Management is presented as a means to promote leadership and cooperation. This project can serve as an inspiration for the coordinators of smaller departments of general medicine at other German universities that are also striving to improve their structure and their position within the university.

  9. Evaluation of general non-reflecting boundary conditions for industrial CFD applications

    NASA Astrophysics Data System (ADS)

    Basara, Branislav; Frolov, Sergei; Lidskii, Boris; Posvyanskii, Vladimir

    2007-11-01

    The importance of having proper boundary conditions for the calculation domain is a known issue in Computational Fluid Dynamics (CFD). In many situations, it is very difficult to define a correct boundary condition. The flow may enter and leave the computational domain at the same time and at the same boundary. In such circumstances, it is important that numerical implementation of boundary conditions enforces certain physical constraints leading to correct results which then ensures a better convergence rate. The aim of this paper is to evaluate recently proposed non-reflecting boundary conditions (Frolov et al., 2001, Advances in Chemical Propulsion) on industrial CFD applications. Derivation of the local non-reflecting boundary conditions at the open boundary is based on finding the solution of linearized Euler equations vanishing at infinity for both incompressible and compressible formulations. This is implemented into the in-house CFD package AVL FIRE and some numerical details will be presented as well. The key applications in this paper are from automotive industry, e.g. an external car aerodynamics, an intake port, etc. The results will show benefits of using effective non-reflecting boundary conditions.

  10. Agreement between patients' self-report and physicians' prescriptions on nonsteroidal anti-inflammatory drugs and other drugs used in musculoskeletal disorders: the international Pharmacoepidemiologic General Research eXtension database.

    PubMed

    Grimaldi-Bensouda, Lamiae; Rossignol, Michel; Aubrun, Elodie; Benichou, Jacques; Abenhaim, Lucien

    2012-07-01

    PURPOSE: The use of prescription records for the assessment of exposure to nonsteroidal anti-inflammatory drugs (NSAIDs) does not capture over-the-counter drug use. This study compared patients' self-reported use to physician's prescriptions for NSAIDs and other drugs used to treat musculoskeletal disorders (MSDs). METHODS: The international Pharmacoepidemiologic General Research eXtension database includes a network of general practitioners recruiting patients without reference to diagnoses or prescriptions. Data on all drug use across France within the 2 years preceding the date of inclusion (index date) were obtained from both patients' self-reports (PSRs) and physicians' prescription reports (PPRs). Patients' reports were obtained using a structured telephone interview combined with an interview guide containing a list of drugs commonly used. Comparisons were made on exposure to four categories of MSD drugs and three time windows up to 24 months before the index date. RESULTS: Agreement between physician and patient reports was assessed on 4152 patient-physician pairs. Bias- and prevalence-adjusted kappa values showed fair agreement for nonaspirin NSAIDs, moderate to fair for nonnarcotic analgesics, high for osteoarthritis and moderate to substantial for muscle relaxants. Over-the-counter drug use was associated with greater disagreement (OR = 2.21, 95%CI = 1.05-1.38). Age was not associated with disagreement. CONCLUSION: Differences between PSR and PPR in estimating the prevalence of MSD drug use varied by the type of drug and the elapsed time from the index date. The patient-assisted interview method used in this study showed better agreement with PPR compared with standard interviews, especially for long time windows and patients older than 65 years. Copyright © 2012 John Wiley & Sons, Ltd.

  11. Describing Antecedent-Behavior-Consequence Relations Using Conditional Probabilities and the General Operant Contingency Space: A Preliminary Investigation

    ERIC Educational Resources Information Center

    Eckert, Tanya L.; Martens, Brian K.; DiGennaro, Florence D.

    2005-01-01

    Antecedent-Behavior-Consequence (A-B-C) recordings are often used in school settings as part of a functional assessment. A number of limitations are associated with A-B-C recordings, and a novel approach for describing data from A-B-C recordings is to compute conditional probabilities that can be graphed in the general operant contingency space to…

  12. A Comprehensive Test of General Strain Theory: Key Strains, Situational- and Trait-Based Negative Emotions, Conditioning Factors, and Delinquency

    ERIC Educational Resources Information Center

    Moon, Byongook; Morash, Merry; McCluskey, Cynthia Perez; Hwang, Hye-Won

    2009-01-01

    Using longitudinal data on South Korean youth, the authors addressed limitations of previous tests of general strain theory (GST), focusing on the relationships among key strains, situational- and trait-based negative emotions, conditioning factors, and delinquency. Eight types of strain previously shown most likely to result in delinquency,…

  13. 7 CFR 301.76-5 - General conditions governing the issuance of any certificate or limited permit; provisions for...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Citrus Greening and Asian Citrus Psyllid § 301.76-5 General conditions governing the issuance of any certificate or limited... Act (7 U.S.C. 7714) 2 /> to prevent the spread of Asian citrus psyllid; and 2 An inspector may...

  14. 7 CFR 301.76-5 - General conditions governing the issuance of any certificate or limited permit; provisions for...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Citrus Greening and Asian Citrus Psyllid § 301.76-5 General conditions governing the issuance of any certificate or limited... Act (7 U.S.C. 7714) 2 /> to prevent the spread of Asian citrus psyllid; and 2 An inspector may...

  15. 7 CFR 301.76-5 - General conditions governing the issuance of any certificate or limited permit; provisions for...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Citrus Greening and Asian Citrus Psyllid § 301.76-5 General conditions governing the issuance of any certificate or limited... Act (7 U.S.C. 7714) 2 /> to prevent the spread of Asian citrus psyllid; and 2 An inspector may...

  16. 7 CFR 301.76-5 - General conditions governing the issuance of any certificate or limited permit; provisions for...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Citrus Greening and Asian Citrus Psyllid § 301.76-5 General conditions governing the issuance of any certificate or limited... Act (7 U.S.C. 7714) 2 to prevent the spread of Asian citrus psyllid; and 2 An inspector may hold...

  17. 10 CFR 72.212 - Conditions of general license issued under § 72.210.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... this general license, personnel searches required by § 73.55(h) of this chapter before admission to a new protected area may be performed by physical pat-down searches of persons in lieu of firearms and... performed on the cask. (ii) This record must include sufficient information to furnish documentary...

  18. 40 CFR 86.1810-01 - General standards; increase in emissions; unsafe conditions; waivers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... United States may be used to determine combined volume, at the manufacturers option. Tables S01-3, S01-4... for sale in the United States may be used to determine combined volume, at the manufacturers option... VEHICLES AND ENGINES (CONTINUED) General Compliance Provisions for Control of Air Pollution From New and...

  19. 40 CFR 86.1810-01 - General standards; increase in emissions; unsafe conditions; waivers.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... United States may be used to determine combined volume, at the manufacturers option. Tables S01-3, S01-4... for sale in the United States may be used to determine combined volume, at the manufacturers option... VEHICLES AND ENGINES (CONTINUED) General Compliance Provisions for Control of Air Pollution From New and...

  20. 40 CFR 86.1810-01 - General standards; increase in emissions; unsafe conditions; waivers.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... United States may be used to determine combined volume, at the manufacturers option. Tables S01-3, S01-4... for sale in the United States may be used to determine combined volume, at the manufacturers option... VEHICLES AND ENGINES (CONTINUED) General Compliance Provisions for Control of Air Pollution From New and...

  1. 40 CFR 86.1810-01 - General standards; increase in emissions; unsafe conditions; waivers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... United States may be used to determine combined volume, at the manufacturers option. Tables S01-3, S01-4... for sale in the United States may be used to determine combined volume, at the manufacturers option... VEHICLES AND ENGINES (CONTINUED) General Compliance Provisions for Control of Air Pollution From New and...

  2. 40 CFR 86.1810-01 - General standards; increase in emissions; unsafe conditions; waivers.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... VEHICLES AND ENGINES General Compliance Provisions for Control of Air Pollution From New and In-Use Light... United States may be used to determine combined volume, at the manufacturers option. Tables S01-3, S01-4... for sale in the United States may be used to determine combined volume, at the manufacturers...

  3. Prevalence of Chronic Medical Conditions in Adults with Mental Retardation: Comparison with the General Population.

    ERIC Educational Resources Information Center

    Kapell, Deborah; Nightingale, Beryle; Rodriguez, Ana; Lee, Joseph H.; Zigman, Warren B.; Schupf, Nicole

    1998-01-01

    A study interviewed caregivers and reviewed medical records of 278 adults with mental retardation with and without Down syndrome. The adults with mental retardation had age-related disorders comparable to those in the general population, but there was an increased frequency of thyroid disorders, nonischemic heart disorders, and sensory impairment.…

  4. Conditioning- and Time-Dependent Increases in Context Fear and Generalization

    ERIC Educational Resources Information Center

    Poulos, Andrew M.; Mehta, Nehali; Lu, Bryan; Amir, Dorsa; Livingston, Briana; Santarelli, Anthony; Zhuravka, Irina; Fanselow, Michael S.

    2016-01-01

    A prominent feature of fear memories and anxiety disorders is that they endure across extended periods of time. Here, we examine how the severity of the initial fear experience influences incubation, generalization, and sensitization of contextual fear memories across time. Adult rats were presented with either five, two, one, or zero shocks (1.2…

  5. Maladaptive behavioral consequences of conditioned fear-generalization: a pronounced, yet sparsely studied, feature of anxiety pathology.

    PubMed

    van Meurs, Brian; Wiggert, Nicole; Wicker, Isaac; Lissek, Shmuel

    2014-06-01

    Fear-conditioning experiments in the anxiety disorders focus almost exclusively on passive-emotional, Pavlovian conditioning, rather than active-behavioral, instrumental conditioning. Paradigms eliciting both types of conditioning are needed to study maladaptive, instrumental behaviors resulting from Pavlovian abnormalities found in clinical anxiety. One such Pavlovian abnormality is generalization of fear from a conditioned danger-cue (CS+) to resembling stimuli. Though lab-based findings repeatedly link overgeneralized Pavlovian-fear to clinical anxiety, no study assesses the degree to which Pavlovian overgeneralization corresponds with maladaptive, overgeneralized instrumental-avoidance. The current effort fills this gap by validating a novel fear-potentiated startle paradigm including Pavlovian and instrumental components. The paradigm is embedded in a computer game during which shapes appear on the screen. One shape paired with electric-shock serves as CS+, and other resembling shapes, presented in the absence of shock, serve as generalization stimuli (GSs). During the game, participants choose whether to behaviorally avoid shock at the cost of poorer performance. Avoidance during CS+ is considered adaptive because shock is a real possibility. By contrast, avoidance during GSs is considered maladaptive because shock is not a realistic prospect and thus unnecessarily compromises performance. Results indicate significant Pavlovian-instrumental relations, with greater generalization of Pavlovian fear associated with overgeneralization of maladaptive instrumental-avoidance.

  6. Maladaptive Behavioral Consequences of Conditioned Fear-Generalization: A Pronounced, Yet Sparsely Studied, Feature of Anxiety Pathology

    PubMed Central

    van Meurs, Brian; Wiggert, Nicole; Wicker, Isaac; Lissek, Shmuel

    2016-01-01

    Fear-conditioning experiments in the anxiety disorders focus almost exclusively on passive-emotional, Pavlovian conditioning, rather than active-behavioral, instrumental conditioning. Paradigms eliciting both types of conditioning are needed to study maladaptive, instrumental behaviors resulting from Pavlovian abnormalities found in clinical anxiety. One such Pavlovian abnormality is generalization of fear from a conditioned danger-cue (CS+) to resembling stimuli. Though lab-based findings repeatedly link overgeneralized Pavlovian-fear to clinical anxiety, no study assesses the degree to which Pavlovian overgeneralization corresponds with maladaptive, overgeneralized instrumental-avoidance. The current effort fills this gap by validating a novel fear-potentiated startle paradigm including Pavlovian and instrumental components. The paradigm is embedded in a computer game during which shapes appear on the screen. One shape paired with electric-shock serves as CS+, and other resembling shapes, presented in the absence of shock, serve as generalization stimuli (GSs). During the game, participants choose whether to behaviorally avoid shock at the cost of poorer performance. Avoidance during CS+ is considered adaptive because shock is a real possibility. By contrast, avoidance during GSs is considered maladaptive because shock is not a realistic prospect and thus unnecessarily compromises performance. Results indicate significant Pavlovian-instrumental relations, with greater generalization of Pavlovian fear associated with overgeneralization of maladaptive instrumental-avoidance. PMID:24768950

  7. Reversibility of a quantum channel: General conditions and their applications to Bosonic linear channels

    SciTech Connect

    Shirokov, M. E.

    2013-11-15

    The method of complementary channel for analysis of reversibility (sufficiency) of a quantum channel with respect to families of input states (pure states for the most part) are considered and applied to Bosonic linear (quasi-free) channels, in particular, to Bosonic Gaussian channels. The obtained reversibility conditions for Bosonic linear channels have clear physical interpretation and their sufficiency is also shown by explicit construction of reversing channels. The method of complementary channel gives possibility to prove necessity of these conditions and to describe all reversed families of pure states in the Schrodinger representation. Some applications in quantum information theory are considered. Conditions for existence of discrete classical-quantum subchannels and of completely depolarizing subchannels of a Bosonic linear channel are presented.

  8. Generalized nematohydrodynamic boundary conditions with application to bistable twisted nematic liquid-crystal displays.

    PubMed

    Fang, Angbo; Qian, Tiezheng; Sheng, Ping

    2008-12-01

    Parallel to the highly successful Ericksen-Leslie hydrodynamic theory for the bulk behavior of nematic liquid crystals (NLCs), we derive a set of coupled hydrodynamic boundary conditions to describe the NLC dynamics near NLC-solid interfaces. In our boundary conditions, translational flux (flow slippage) and rotational flux (surface director relaxation) are coupled according to the Onsager variational principle of least energy dissipation. The application of our boundary conditions to the truly bistable pi -twist NLC cell reveals a complete picture of the dynamic switching processes. It is found that the thus far overlooked translation-rotation dissipative coupling at solid surfaces can accelerate surface director relaxation and enhance the flow rate. This can be utilized to improve the performance of electro-optical nematic devices by lowering the required switching voltages and reducing the switching times.

  9. A general mechanism for conditional expression of exaggerated sexually-selected traits.

    PubMed

    Warren, Ian A; Gotoh, Hiroki; Dworkin, Ian M; Emlen, Douglas J; Lavine, Laura C

    2013-10-01

    Sexually-selected exaggerated traits tend to be unusually reliable signals of individual condition, as their expression tends to be more sensitive to nutritional history and physiological circumstance than that of other phenotypes. As such, these traits are the foundation for many models of sexual selection and animal communication, such as "handicap" and "good genes" models. Exactly how expression of these traits is linked to the bearer's condition has been a central yet unresolved question, in part because the underlying physiological mechanisms regulating their development have remained largely unknown. Recent discoveries across animals as diverse as deer, beetles, and flies now implicate the widely conserved insulin-like signaling pathway, as a common physiological mechanism regulating condition-sensitive structures with extreme growth. This raises the exciting possibility that one highly conserved pathway may underlie the evolution of trait exaggeration in a multitude of sexually-selected signal traits across the animal kingdom.

  10. The discovery of the principles of reinforcement, extinction, generalization, and differentiation of conditional reflexes in Pavlov's laboratories.

    PubMed

    Windholz, G

    1989-01-01

    The discovery of reinforcement, extinction, generalization, and differentiation with the conditional reflex method in Pavlov's laboratories is described. Modern American introductory texts show that contemporary understanding of the experimental work on conditioning in Pavlov's laboratories is derived from a 1927 English translation of Pavlov's lectures on the conditional reflexes. The lectures present the discoveries topically, not chronologically. In contrast, this article presents a chronological account of the contributions of S.G. Vul'fson, I.F. Tolochinov, and B.P. Babkin, which led to the conceptualization of reinforcement and extinction, and the work of V.N. Boldyrev and N.A. Kashereninova, which led to the formulation of the concepts of generalization and differentiation. This historical approach avoids giving the impression that the development of the Pavlovian paradigm was a highly systematic pursuit.

  11. General Bohm and Langmuir conditions for a strong double layer in space plasmas

    NASA Technical Reports Server (NTRS)

    Williams, A. C.

    1986-01-01

    The appropriate Bohm and Langmuir conditions when there are three beam-type particles passing through the double layer in addition to the usual two species of trapped particles are derived. It is shown that the Langmuir conditions, which normally imply a net current through the double layer, are consistent with zero net current when the class of accreting ions is included. It is also found that the Bohm criterion is quite different from its usual form, and that it has nothing to do with instabilities of the plasma at some critical level, as is believed to be true.

  12. Agreement between international classification of disease (ICD) and cause of death and associated conditions (CODAC) for the ascertainment of cause of stillbirth (SB) in the rural areas of north India.

    PubMed

    Kaistha, Madhvi; Kumar, Dinesh; Bhardwaj, Ashok

    2016-01-01

    International Classification of Diseases-10 th version (ICD-10) has been used to ascertain the cause of death but its use for stillbirths (SBs) is limited. Cause of Death and Associated Conditions (CODAC) as a detailed system expected to provide the exact cause of SB, so a community-based study was planned to study the level of agreement between ICD-10 and CODAC for ascertaining the cause of SB. A verbal autopsy (VA) tool was used to collect the information and then the cause of each SB was assigned using ICD-10 and CODAC separately. Each tool was used for 87 SBs and found that prolonged singleton labor, maternal pregnancy induced hypertension (PIH), and central nervous system (CNS) related congenital malformations were considered the top three causes. There was a significant agreement between ICD-10 and CODAC but the latter offers a scope to delineate the causes more precisely due to its hierarchal nature. PMID:26911221

  13. Momentum constraints as integrability conditions for the Hamiltonian constraint in general relativity.

    NASA Technical Reports Server (NTRS)

    Moncrief, V.; Teitelboim, C.

    1972-01-01

    It is shown that if the Hamiltonian constraint of general relativity is imposed as a restriction on the Hamilton principal functional in the classical theory, or on the state functional in the quantum theory, then the momentum constraints are automatically satisfied. This result holds both for closed and open spaces and it means that the full content of the theory is summarized by a single functional equation of the Tomonaga-Schwinger type.

  14. New conditions for obtaining the exact solutions of the general Riccati equation.

    PubMed

    Bougoffa, Lazhar

    2014-01-01

    We propose a direct method for solving the general Riccati equation y' = f(x) + g(x)y + h(x)y(2). We first reduce it into an equivalent equation, and then we formulate the relations between the coefficients functions f(x), g(x), and h(x) of the equation to obtain an equivalent separable equation from which the previous equation can be solved in closed form. Several examples are presented to demonstrate the efficiency of this method.

  15. The Generalization of a Conditioned Response to Deception across the Public/Private Barrier

    ERIC Educational Resources Information Center

    Tomash, J. J.; Reed, Phil

    2013-01-01

    Previous attempts at lie detection, such as the polygraph, have relied on physiological arousal to identify deception--but these responses have not proven to be as reliable as is necessary for widespread use. Conditioning procedures have been shown to increase the discriminative physiological arousal exhibited during deception, but have targeted…

  16. 40 CFR 86.1810-09 - General standards; increase in emissions; unsafe condition; waivers.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... cold temperature NMHC emission standards as described in § 86.1811-10(g) apply only at low altitude... altitude conditions for 2009 and later model year vehicles. (2) For vehicles that comply with the cold... described in § 86.1818-12, manufacturers must submit an engineering evaluation indicating that...

  17. 40 CFR 86.090-5 - General standards; increase in emissions; unsafe conditions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... light or heavy duty motor vehicle equipped with an engine certified to the nonroad provision of 40 CFR... standards; increase in emissions; unsafe conditions. (a)(1) Every new motor vehicle (or new motor vehicle... with respect to any Otto-cycle or diesel heavy-duty vehicle which uses an engine which has not...

  18. Low-Flow Liquid Desiccant Air Conditioning: General Guidance and Site Considerations

    SciTech Connect

    Kozubal, E.; Herrmann, L.; Deru, M.; Clark, J.

    2014-09-01

    Dehumidification or latent cooling in buildings is an area of growing interest that has been identified as needing more research and improved technologies for higher performance. Heating, ventilating, and air-conditioning (HVAC) systems typically expend excessive energy by using overcool-and-reheat strategies to dehumidify buildings. These systems first overcool ventilation air to remove moisture and then reheat the air to meet comfort requirements. Another common strategy incorporates solid desiccant rotors that remove moisture from the air more efficiently; however, these systems increase fan energy consumption because of the high airside pressure drop of solid desiccant rotors and can add heat of absorption to the ventilation air. Alternatively, liquid desiccant air-conditioning (LDAC) technology provides an innovative dehumidification solution that: (1) eliminates the need for overcooling and reheating from traditional cooling systems; and (2) avoids the increased fan energy and air heating from solid desiccant rotor systems.

  19. Agreement among 2 x 2 Agreement Indices.

    ERIC Educational Resources Information Center

    Conger, Anthony J.; Ward, David G.

    1984-01-01

    Sixteen measures of reliability for two-category nominal scales are compared. Upon correcting for chance agreement, there are only five distinct indices: Fleiss's modification of A-sub-1, the phi coefficient, Cohen's kappa, and two intraclass coefficients. Recommendations for choosing an agreement index are made based on definitions, magnitude,…

  20. A General Optimality Conditions for Stochastic Control Problems of Jump Diffusions

    SciTech Connect

    Bahlali, Seid; Chala, Adel

    2012-02-15

    We consider a stochastic control problem where the system is governed by a non linear stochastic differential equation with jumps. The control is allowed to enter into both diffusion and jump terms. By only using the first order expansion and the associated adjoint equation, we establish necessary as well as sufficient optimality conditions of controls for relaxed controls, who are a measure-valued processes.

  1. Generalized INF-SUP condition for Chebyshev approximation of the Navier-Stokes equations

    NASA Technical Reports Server (NTRS)

    Bernardi, Christine; Canuto, Claudio; Maday, Yvon

    1986-01-01

    An abstract mixed problem and its approximation are studied; both are well-posed if and only if several inf-sup conditions are satisfied. These results are applied to a spectral Galerkin method for the Stokes problem in a square, when it is formulated in Chebyshev weighted Sobolev spaces. Finally, a collocation method for the Navier-Stokes equations at Chebyshev nodes is analyzed.

  2. Beam wandering statistics of twin thin laser beam propagation under generalized atmospheric conditions.

    PubMed

    Pérez, Darío G; Funes, Gustavo

    2012-12-01

    Under the Geometrics Optics approximation is possible to estimate the covariance between the displacements of two thin beams after they have propagated through a turbulent medium. Previous works have concentrated in long propagation distances to provide models for the wandering statistics. These models are useful when the separation between beams is smaller than the propagation path-regardless of the characteristics scales of the turbulence. In this work we give a complete model for these covariances, behavior introducing absolute limits to the validity of former approximations. Moreover, these generalizations are established for non-Kolmogorov atmospheric models.

  3. New Conditions for Obtaining the Exact Solutions of the General Riccati Equation

    PubMed Central

    Bougoffa, Lazhar

    2014-01-01

    We propose a direct method for solving the general Riccati equation y′ = f(x) + g(x)y + h(x)y2. We first reduce it into an equivalent equation, and then we formulate the relations between the coefficients functions f(x), g(x), and h(x) of the equation to obtain an equivalent separable equation from which the previous equation can be solved in closed form. Several examples are presented to demonstrate the efficiency of this method. PMID:25202724

  4. General Anesthetic Conditions Induce Network Synchrony and Disrupt Sensory Processing in the Cortex

    PubMed Central

    Lissek, Thomas; Obenhaus, Horst A.; Ditzel, Désirée A. W.; Nagai, Takeharu; Miyawaki, Atsushi; Sprengel, Rolf; Hasan, Mazahir T.

    2016-01-01

    General anesthetics are commonly used in animal models to study how sensory signals are represented in the brain. Here, we used two-photon (2P) calcium activity imaging with cellular resolution to investigate how neuronal activity in layer 2/3 of the mouse barrel cortex is modified under the influence of different concentrations of chemically distinct general anesthetics. Our results show that a high isoflurane dose induces synchrony in local neuronal networks and these cortical activity patterns closely resemble those observed in EEG recordings under deep anesthesia. Moreover, ketamine and urethane also induced similar activity patterns. While investigating the effects of deep isoflurane anesthesia on whisker and auditory evoked responses in the barrel cortex, we found that dedicated spatial regions for sensory signal processing become disrupted. We propose that our isoflurane-2P imaging paradigm can serve as an attractive model system to dissect cellular and molecular mechanisms that induce the anesthetic state, and it might also provide important insight into sleep-like brain states and consciousness. PMID:27147963

  5. A new technique for simulating composite material. Task 2: Analytical solutions with Generalized Impedance Boundary Conditions (GIBCs)

    NASA Technical Reports Server (NTRS)

    Ricoy, M. A.; Volakis, J. L.

    1989-01-01

    The diffraction problem associated with a multilayer material slab recessed in a perfectly conducting ground plane is formulated and solved via the Generalized Scattering Matrix Formulation (GSMF) in conjunction with the dual integral equation approach. The multilayer slab is replaced by a surface obeying a generalized impedance boundary condition (GIBC) to facilitate the computation of the pertinent Wiener Hopf split functions and their zeros. Both E(sub z) and H(sub z) polarizations are considered and a number of scattering patterns are presented, some of which are compared to exact results available for a homogeneous recessed slab.

  6. Existence and stability, and discrete BB and rank conditions, for general mixed-hybrid finite elements in elasticity

    NASA Technical Reports Server (NTRS)

    Xue, W.-M.; Atluri, S. N.

    1985-01-01

    In this paper, all possible forms of mixed-hybrid finite element methods that are based on multi-field variational principles are examined as to the conditions for existence, stability, and uniqueness of their solutions. The reasons as to why certain 'simplified hybrid-mixed methods' in general, and the so-called 'simplified hybrid-displacement method' in particular (based on the so-called simplified variational principles), become unstable, are discussed. A comprehensive discussion of the 'discrete' BB-conditions, and the rank conditions, of the matrices arising in mixed-hybrid methods, is given. Some recent studies aimed at the assurance of such rank conditions, and the related problem of the avoidance of spurious kinematic modes, are presented.

  7. 19 CFR 118.3 - Written agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false Written agreement. 118.3 Section 118.3 Customs... CENTRALIZED EXAMINATION STATIONS General Provisions § 118.3 Written agreement. The applicant tentatively selected to operate a CES must sign a written agreement with CBP before commencing operations. Failure...

  8. 19 CFR 118.3 - Written agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Written agreement. 118.3 Section 118.3 Customs... CENTRALIZED EXAMINATION STATIONS General Provisions § 118.3 Written agreement. The applicant tentatively selected to operate a CES must sign a written agreement with CBP before commencing operations. Failure...

  9. 19 CFR 118.3 - Written agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false Written agreement. 118.3 Section 118.3 Customs... CENTRALIZED EXAMINATION STATIONS General Provisions § 118.3 Written agreement. The applicant tentatively selected to operate a CES must sign a written agreement with CBP before commencing operations. Failure...

  10. 19 CFR 118.3 - Written agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false Written agreement. 118.3 Section 118.3 Customs... CENTRALIZED EXAMINATION STATIONS General Provisions § 118.3 Written agreement. The applicant tentatively selected to operate a CES must sign a written agreement with CBP before commencing operations. Failure...

  11. 19 CFR 118.3 - Written agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Written agreement. 118.3 Section 118.3 Customs... CENTRALIZED EXAMINATION STATIONS General Provisions § 118.3 Written agreement. The applicant tentatively selected to operate a CES must sign a written agreement with Customs before commencing operations....

  12. 24 CFR 964.335 - Grant agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Grant agreement. 964.335 Section... § 964.335 Grant agreement. (a) General. HUD will enter into a grant agreement with the recipients of a Family Investment Centers grant which defines the legal framework for the relationship between HUD and...

  13. 24 CFR 964.215 - Grant agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Grant agreement. 964.215 Section... Grant agreement. (a) General. HUD shall enter into a grant agreement with the recipient of a technical assistance grant which defines the legal framework for the relationship between HUD and a resident council...

  14. 24 CFR 964.215 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Grant agreement. 964.215 Section... Grant agreement. (a) General. HUD shall enter into a grant agreement with the recipient of a technical assistance grant which defines the legal framework for the relationship between HUD and a resident council...

  15. 24 CFR 964.215 - Grant agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Grant agreement. 964.215 Section... Grant agreement. (a) General. HUD shall enter into a grant agreement with the recipient of a technical assistance grant which defines the legal framework for the relationship between HUD and a resident council...

  16. 24 CFR 964.335 - Grant agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Grant agreement. 964.335 Section... § 964.335 Grant agreement. (a) General. HUD will enter into a grant agreement with the recipients of a Family Investment Centers grant which defines the legal framework for the relationship between HUD and...

  17. 24 CFR 964.335 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Grant agreement. 964.335 Section... § 964.335 Grant agreement. (a) General. HUD will enter into a grant agreement with the recipients of a Family Investment Centers grant which defines the legal framework for the relationship between HUD and...

  18. Generalization peak shift in rats under conditions of positive reinforcement and avoidance.

    PubMed

    Weiss, S J; Schindler, C W

    1981-03-01

    Rats were trained to discriminate between two click frequencies. One frequency was associated with either variable-interval food reinforcement (Experiment 1) or free-operant avoidance (Experiment 2). The other frequency was associated with the absence of food in Experiment 1 and the absence of shock in Experiment 2. On a click frequency generalization test, the rats in both experiments showed positive peak shift with the shape of the relative gradients being very similar. This is the first reported instance of peak shift in rats when responding was maintained by an avoidance contingency. Nondifferentially trained controls showed that this shift was due exclusively to associative processes, with nonassociative stimulus factors in themselves apparently making no contribution to increased rates at particular stimulus values. These results show the comparability of appetitive and aversive control and support the position that gradient differences do not result from approach versus avoidance per se.

  19. Generalization peak shift in rats under conditions of positive reinforcement and avoidance

    PubMed Central

    Weiss, Stanley J.; Schindler, Charles W.

    1981-01-01

    Rats were trained to discriminate between two click frequencies. One frequency was associated with either variable-interval food reinforcement (Experiment 1) or free-operant avoidance (Experiment 2). The other frequency was associated with the absence of food in Experiment 1 and the absence of shock in Experiment 2. On a click frequency generalization test, the rats in both experiments showed positive peak shift with the shape of the relative gradients being very similar. This is the first reported instance of peak shift in rats when responding was maintained by an avoidance contingency. Nondifferentially trained controls showed that this shift was due exclusively to associative processes, with nonassociative stimulus factors in themselves apparently making no contribution to increased rates at particular stimulus values. These results show the comparability of appetitive and aversive control and support the position that gradient differences do not result from approach versus avoidance per se. PMID:16812208

  20. General coalescence conditions for the exact wave functions. II. Higher-order relations for many-particle systems

    SciTech Connect

    Kurokawa, Yusaku I. E-mail: h.nakatsuji@qcri.or.jp; Nakashima, Hiroyuki; Nakatsuji, Hiroshi E-mail: h.nakatsuji@qcri.or.jp

    2014-06-07

    We derived the necessary conditions that must be satisfied by the non-relativistic time-independent exact wave functions for many-particle systems at a two-particle coalescence (or cusp) point. Some simple conditions are known to be Kato's cusp condition (CC) and Rassolov and Chipman's CC. In a previous study, we derived an infinite number of necessary conditions that two-particle wave functions must satisfy at a coalescence point. In the present study, we extend these conditions to many-particle systems. They are called general coalescence conditions (GCCs), and Kato's CC and Rassolov and Chipman's CC are included as special conditions. GCCs can be applied not only to Coulombic systems but also to any system in which the interaction between two particles is represented in a power series of inter-particle distances. We confirmed the correctness of our derivation of the GCCs by applying the exact wave function of a harmonium in electron-electron and electron-nucleus coalescence situations. In addition, we applied the free complement (FC) wave functions of a helium atom to the GCCs to examine the accuracy of the FC wave function in the context of a coalescence situation.

  1. General rules prospected for the liquid fragility in various material groups and different thermodynamic conditions.

    PubMed

    Paluch, M; Masiewicz, E; Grzybowski, A; Pawlus, S; Pionteck, J; Wojnarowska, Z

    2014-10-01

    The fragility parameter has been acknowledged as one of the most important characteristics of glass-forming liquids. We show that the mystery of the dramatic change in molecular dynamics of systems approaching the glass transition can be better understood by the high pressure study of fragility parameters defined in different thermodynamic conditions. We formulate and experimentally confirm a few rules obeyed by the fragility parameters, which are also rationalized by the density scaling law and its modification suggested for associated liquids. In this way, we successfully explore and gain a new insight into the pressure effect on molecular dynamics of van der Waals liquids, polymer melts, ionic liquids, and hydrogen-bonded systems near the glass transition. PMID:25296821

  2. General rules prospected for the liquid fragility in various material groups and different thermodynamic conditions

    SciTech Connect

    Paluch, M.; Masiewicz, E.; Grzybowski, A.; Pawlus, S.; Wojnarowska, Z.; Pionteck, J.

    2014-10-07

    The fragility parameter has been acknowledged as one of the most important characteristics of glass-forming liquids. We show that the mystery of the dramatic change in molecular dynamics of systems approaching the glass transition can be better understood by the high pressure study of fragility parameters defined in different thermodynamic conditions. We formulate and experimentally confirm a few rules obeyed by the fragility parameters, which are also rationalized by the density scaling law and its modification suggested for associated liquids. In this way, we successfully explore and gain a new insight into the pressure effect on molecular dynamics of van der Waals liquids, polymer melts, ionic liquids, and hydrogen-bonded systems near the glass transition.

  3. Displacement Models for THUNDER Actuators having General Loads and Boundary Conditions

    NASA Technical Reports Server (NTRS)

    Wieman, Robert; Smith, Ralph C.; Kackley, Tyson; Ounaies, Zoubeida; Bernd, Jeff; Bushnell, Dennis M. (Technical Monitor)

    2001-01-01

    This paper summarizes techniques for quantifying the displacements generated in THUNDER actuators in response to applied voltages for a variety of boundary conditions and exogenous loads. The PDE (partial differential equations) models for the actuators are constructed in two steps. In the first, previously developed theory quantifying thermal and electrostatic strains is employed to model the actuator shapes which result from the manufacturing process and subsequent repoling. Newtonian principles are then employed to develop PDE models which quantify displacements in the actuator due to voltage inputs to the piezoceramic patch. For this analysis, drive levels are assumed to be moderate so that linear piezoelectric relations can be employed. Finite element methods for discretizing the models are developed and the performance of the discretized models are illustrated through comparison with experimental data.

  4. General contamination criteria for optical surfaces. [instrument performance losses in spaceborne conditions

    NASA Technical Reports Server (NTRS)

    Bremer, J. C.

    1982-01-01

    Physical models are developed for establishing criteria to decide on the acceptable contamination level of optical devices in space-borne conditions. Optical systems can be degraded in terms of decreased throughput, i.e., transmissivity or reflectivity, or increases in the total integrated scatter (TIS). Performance losses can be caused by particulate accretion, molecular film accretion, and impact cratering. A quantitative relationship is defined for film thickness and loss of throughput. Formulas are also developed for cases where induced surface defects are larger than the desired viewing wavelengths, or smaller or of the same order of the observed wavelengths. The techniques are used to quantify the degradation of a VUV solar coronagraph, a VUV stellar telescope, and a solar cell due to TIS. Applications are projected for estimating the contamination sensitivity of specific instruments, assessing the contamination hazard from known particulates, or to define clean room standards.

  5. The Relationship Between Religious Attitudes, Fear of Death and Dying with General Health Condition: A Survey in College Students.

    PubMed

    Nazarzadeh, Milad; Sarokhani, Mandana; Sayehmiri, Kourosh

    2015-10-01

    This study aims to assess the relationship between religious attitudes of Ilam universities students (west of Iran), their perspectives about the fear of self and other's death and dying, with their general health. This paper is an analytic survey in which 351 college students, who were selected by multistage sampling, participated. To measure interested variables, Persian format of standardized self-administered questionnaires was employed. Religious attitudes with odds ratio (OR) of 0.94 (95% CI 0.91-0.97) and fear of self dying with 0.88 (95% CI 0.81-0.96) were identified as a protective factors against the inappropriate general health condition. However, the fear of other's death (OR 1.16; 95% CI 1.05-1.28) was identified as a risk factor. This study showed that people who had more religious attitudes and fear of self dying had better general health as well as the fear of other's death had a significant direct relationship with inappropriate general health condition.

  6. [General condition evaluations by members of ISS missions 1 to 15].

    PubMed

    Stepanova, S I; Savchenko, E G; Lavrent'eva, I N; Nesterov, V F; Rudometkin, N M; Saraev, I F

    2009-01-01

    Traditionally crew questioning about general wellbeing is a part of their psychic monitoring. Information provided during compasses at the Earth's request is included in the neuropsychic section of the weekly crew health report prepared by the medical support group at the Moscow Mission Control Center. Purpose of the work was to analyze the structure content of comments on well-being made by the members of ISS-1-15 crews as well as emotionality of these comments excited by heavy work-rest schedule and length of space duties. Most often well-being evaluations were positive varying within the range from non-committal "all right" and reserved "It's OK" to exaggerated "terrific" "great" "fine"and "perfect"which were more common to astronauts than cosmonauts. Cosmonauts' comments had the seal of personality It was recognized that the demanding work/rest schedule had little impact on the comments and that they did not change with time during 24-wk missions. PMID:19462776

  7. Plates and shells containing a surface crack under general loading conditions

    NASA Technical Reports Server (NTRS)

    Joseph, Paul F.; Erdogan, Fazil

    1987-01-01

    Various through and part-through crack problems in plates and shells are considered. The line-spring model of Rice and Levy is generalized to the skew-symmetric case to solve surface crack problems involving mixed-mode, coplanar crack growth. Compliance functions are introduced which are valid for crack depth to thickness ratios at least up to .95. This includes expressions for tension and bending as well as expressions for in-plane shear, out-of-plane shear, and twisting. Transverse shear deformation is taken into account in the plate and shell theories and this effect is shown to be important in comparing stress intensity factors obtained from the plate theory with three-dimensional solutions. Stress intensity factors for cylinders obtained by the line-spring model also compare well with three-dimensional solution. By using the line-spring approach, stress intensity factors can be obtained for the through crack and for part-through crack of any crack front shape, without recalculation integrals that take up the bulk of the computer time. Therefore, parameter studies involving crack length, crack depth, shell type, and shell curvature are made in some detail. The results will be useful in brittle fracture and in fatigue crack propagation studies. All problems considered are of the mixed boundary value type and are reducted to strongly singular integral equations which make use of the finite-part integrals of Hadamard. The equations are solved numerically in a manner that is very efficient.

  8. Two-Sided Annihilator Condition with Generalized Derivations on Multilinear Polynomials

    PubMed Central

    De Filippis, V.; Scudo, G.; Sorrenti, L.

    2014-01-01

    Let R be a prime ring of characteristic different from 2, with extended centroid C, U its two-sided Utumi quotient ring, F a nonzero generalized derivation of R, f(x1,…, xn) a noncentral multilinear polynomial over C in n noncommuting variables, and a, b ∈ R such that a[F(f(r1,…, rn)), f(r1,…, rn)]b = 0 for any r1,…, rn ∈ R. Then one of the following holds: (1) a = 0; (2) b = 0; (3) there exists λ ∈ C such that F(x) = λx, for all x ∈ R; (4) there exist q ∈ U and λ ∈ C such that F(x) = (q + λ)x + xq, for all x ∈ R, and f(x1,…, xn)2 is central valued on R; (5) there exist q ∈ U and λ, μ ∈ C such that F(x) = (q + λ)x + xq, for all x ∈ R, and aq = μa, qb = μb. PMID:27379311

  9. A Report of Three Cases With Acquired Generalized Lipodystrophy With Distinct Autoimmune Conditions Treated With Metreleptin

    PubMed Central

    Lebastchi, Jasmin; Ajluni, Nevin; Neidert, Adam

    2015-01-01

    Context: Acquired generalized lipodystrophy (AGL) is associated with leptin deficiency as a result of adipose tissue loss and hypertriglyceridemia, insulin resistance, and hepatic steatosis. It may coexist with other autoimmune diseases such as Hashimoto's thyroiditis, rheumatoid arthritis, hemolytic anemia, and chronic active hepatitis. Metreleptin therapy has been shown to improve metabolic abnormalities in lipodystrophy, but the effect on AGL patients with active autoimmune disease is unknown. Case Description: We report 3 cases of pediatric patients with AGL and distinct active autoimmune diseases who were treated with metreleptin over a period of 4–6 years. Case 1 is a 9-year-old girl with active juvenile dermatomyositis, who was successfully treated with leptin with no worsening of her dermatomoysitis. Case 2 is a 16-year-old female with Graves' disease, who could discontinue all her antidiabetic medication completely with improved triglyceride levels. Case 3 is an 11-year-old boy with active autoimmune hepatitis and chronic urticaria, whose hyperphagia has resolved and his liver enzymes and hepatosplenomegaly have improved. Conclusion: Metreleptin therapy is of considerable clinical benefit to reduce insulin resistance and hypertriglyceridemia and did not appear to alter the clinical course of autoimmune disease nor clinical efficacy of immunosuppressive treatments. Our observations suggest that risk or presence of autoimmune disease should not lead to withholding of metreleptin treatment from patients with AGL, but should prompt close clinical follow up in light of cautionary preclinical data. PMID:26390101

  10. 47 CFR 51.3 - Applicability to negotiated agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... (CONTINUED) INTERCONNECTION General Information § 51.3 Applicability to negotiated agreements. To the extent... interconnection agreement adopted by negotiation even if the terms of the agreement do not comply with...

  11. Well-conditioning global-local analysis using stable generalized/extended finite element method for linear elastic fracture mechanics

    NASA Astrophysics Data System (ADS)

    Malekan, Mohammad; Barros, Felicio Bruzzi

    2016-07-01

    Using the locally-enriched strategy to enrich a small/local part of the problem by generalized/extended finite element method (G/XFEM) leads to non-optimal convergence rate and ill-conditioning system of equations due to presence of blending elements. The local enrichment can be chosen from polynomial, singular, branch or numerical types. The so-called stable version of G/XFEM method provides a well-conditioning approach when only singular functions are used in the blending elements. This paper combines numeric enrichment functions obtained from global-local G/XFEM method with the polynomial enrichment along with a well-conditioning approach, stable G/XFEM, in order to show the robustness and effectiveness of the approach. In global-local G/XFEM, the enrichment functions are constructed numerically from the solution of a local problem. Furthermore, several enrichment strategies are adopted along with the global-local enrichment. The results obtained with these enrichments strategies are discussed in detail, considering convergence rate in strain energy, growth rate of condition number, and computational processing. Numerical experiments show that using geometrical enrichment along with stable G/XFEM for global-local strategy improves the convergence rate and the conditioning of the problem. In addition, results shows that using polynomial enrichment for global problem simultaneously with global-local enrichments lead to ill-conditioned system matrices and bad convergence rate.

  12. Well-conditioning global-local analysis using stable generalized/extended finite element method for linear elastic fracture mechanics

    NASA Astrophysics Data System (ADS)

    Malekan, Mohammad; Barros, Felicio Bruzzi

    2016-11-01

    Using the locally-enriched strategy to enrich a small/local part of the problem by generalized/extended finite element method (G/XFEM) leads to non-optimal convergence rate and ill-conditioning system of equations due to presence of blending elements. The local enrichment can be chosen from polynomial, singular, branch or numerical types. The so-called stable version of G/XFEM method provides a well-conditioning approach when only singular functions are used in the blending elements. This paper combines numeric enrichment functions obtained from global-local G/XFEM method with the polynomial enrichment along with a well-conditioning approach, stable G/XFEM, in order to show the robustness and effectiveness of the approach. In global-local G/XFEM, the enrichment functions are constructed numerically from the solution of a local problem. Furthermore, several enrichment strategies are adopted along with the global-local enrichment. The results obtained with these enrichments strategies are discussed in detail, considering convergence rate in strain energy, growth rate of condition number, and computational processing. Numerical experiments show that using geometrical enrichment along with stable G/XFEM for global-local strategy improves the convergence rate and the conditioning of the problem. In addition, results shows that using polynomial enrichment for global problem simultaneously with global-local enrichments lead to ill-conditioned system matrices and bad convergence rate.

  13. 44 CFR 206.44 - FEMA-State Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Agreement imposes binding obligations on FEMA, States, their local governments, and private nonprofit... Households Program. (b) Terms and conditions. This Agreement describes the incident and the incident...

  14. A General Model of Distant Hybridization Reveals the Conditions for Extinction in Atlantic Salmon and Brown Trout

    PubMed Central

    Quilodrán, Claudio S.; Currat, Mathias; Montoya-Burgos, Juan I.

    2014-01-01

    Interspecific hybridization is common in nature but can be increased in frequency or even originated by human actions, such as species introduction or habitat modification, which may threaten species persistence. When hybridization occurs between distantly related species, referred to as “distant hybridization,” the resulting hybrids are generally infertile or fertile but do not undergo chromosomal recombination during gametogenesis. Here, we present a model describing this frequent but poorly studied interspecific hybridization to assess its consequences on parental species and to anticipate the conditions under which they can reach extinction. Our general model fully incorporates three important processes: density-dependent competition, dominance/recessivity inheritance of traits and assortative mating. We demonstrate its use and flexibility by assessing population extinction risk between Atlantic salmon and brown trout in Norway, whose interbreeding has recently increased due to farmed fish releases into the wild. We identified the set of conditions under which hybridization may threaten salmonid species. Thanks to the flexibility of our model, we evaluated the effect of an additional risk factor, a parasitic disease, and showed that the cumulative effects dramatically increase the extinction risk. The consequences of distant hybridization are not genetically, but demographically mediated. Our general model is useful to better comprehend the evolution of such hybrid systems and we demonstrated its importance in the field of conservation biology to set up management recommendations when this increasingly frequent type of hybridization is in action. PMID:25003336

  15. A general model of distant hybridization reveals the conditions for extinction in Atlantic salmon and brown trout.

    PubMed

    Quilodrán, Claudio S; Currat, Mathias; Montoya-Burgos, Juan I

    2014-01-01

    Interspecific hybridization is common in nature but can be increased in frequency or even originated by human actions, such as species introduction or habitat modification, which may threaten species persistence. When hybridization occurs between distantly related species, referred to as "distant hybridization," the resulting hybrids are generally infertile or fertile but do not undergo chromosomal recombination during gametogenesis. Here, we present a model describing this frequent but poorly studied interspecific hybridization to assess its consequences on parental species and to anticipate the conditions under which they can reach extinction. Our general model fully incorporates three important processes: density-dependent competition, dominance/recessivity inheritance of traits and assortative mating. We demonstrate its use and flexibility by assessing population extinction risk between Atlantic salmon and brown trout in Norway, whose interbreeding has recently increased due to farmed fish releases into the wild. We identified the set of conditions under which hybridization may threaten salmonid species. Thanks to the flexibility of our model, we evaluated the effect of an additional risk factor, a parasitic disease, and showed that the cumulative effects dramatically increase the extinction risk. The consequences of distant hybridization are not genetically, but demographically mediated. Our general model is useful to better comprehend the evolution of such hybrid systems and we demonstrated its importance in the field of conservation biology to set up management recommendations when this increasingly frequent type of hybridization is in action.

  16. 10 CFR 950.10 - Conditional agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... docketed by the Commission pursuant to 10 CFR part 52, and if applicable, an electronic copy of the design... including the credit structure and all sources and uses of funds for the project, the most recent private..., effective Sept. 11, 2006. Paragraph (b) of this text contains information collection and...

  17. 10 CFR 950.10 - Conditional agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... docketed by the Commission pursuant to 10 CFR part 52, and if applicable, an electronic copy of the design... including the credit structure and all sources and uses of funds for the project, the most recent private..., effective Sept. 11, 2006. Paragraph (b) of this text contains information collection and...

  18. 10 CFR 950.10 - Conditional agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... docketed by the Commission pursuant to 10 CFR part 52, and if applicable, an electronic copy of the design... including the credit structure and all sources and uses of funds for the project, the most recent private..., effective Sept. 11, 2006. Paragraph (b) of this text contains information collection and...

  19. 10 CFR 950.10 - Conditional agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... docketed by the Commission pursuant to 10 CFR part 52, and if applicable, an electronic copy of the design... including the credit structure and all sources and uses of funds for the project, the most recent private..., effective Sept. 11, 2006. Paragraph (b) of this text contains information collection and...

  20. 10 CFR 950.10 - Conditional agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... docketed by the Commission pursuant to 10 CFR part 52, and if applicable, an electronic copy of the design... including the credit structure and all sources and uses of funds for the project, the most recent private..., effective Sept. 11, 2006. Paragraph (b) of this text contains information collection and...

  1. 46 CFR 8.130 - Agreement conditions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... certificates issued by, an authorized classification society will be accepted as functions performed by, or certificates issued by, the Coast Guard, provided that the classification society maintains compliance with all... classification society authorizing the performance of delegated functions will be written and will require...

  2. 46 CFR 8.130 - Agreement conditions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... certificates issued by, an authorized classification society will be accepted as functions performed by, or certificates issued by, the Coast Guard, provided that the classification society maintains compliance with all... classification society authorizing the performance of delegated functions will be written and will require...

  3. 46 CFR 8.130 - Agreement conditions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... function in the English language. (2) Maintain a corporate office in the United States that has adequate... English language, on all vessels for which the classification society has performed any delegated function....S. supplement to class rules. (14) Make available to the Coast Guard all records, in the...

  4. Sexual Agreements among Gay Male Couples

    PubMed Central

    Hoff, Colleen H.; Beougher, Sean C.

    2009-01-01

    Many gay male couples make agreements about whether or not to permit sex with outside partners, yet little is known about the development and maintenance of these agreements, their impact on relationships, and whether they are an effective HIV prevention strategy. Using semi-structured, qualitative interviews, 39 gay male couples were asked about their sexual agreements and about other relationship dynamics that might affect their agreements. Analysis revealed a wide range of agreement types, all of which are presented along a continuum rather than as discrete categories. For couples with open agreements, most placed rules or conditions limiting when, where, how often, and with whom outside sex was permitted. Although motivations for having agreements varied, HIV prevention did not rank as a primary factor for any couple. Most couples had congruous agreements; however, a small number reported discrepancies which may increase HIV transmission risk. How couples handled breaks in their agreements also varied, depending on what condition was broken, whether it was disclosed, and the partner's reaction. Additional results include differences in agreement type and motivations for having an agreement based on couple serostatus. Overall, agreements benefited couples by providing boundaries for the relationship, supporting a non-heteronormative identity, and fulfilling the sexual needs of the couple. Future prevention efforts involving gay couples must address the range of agreement types and the meanings couples ascribe to them, in addition to tempering safety messages with the relationship issues that are important to and faced by gay couples. PMID:18686027

  5. Charging free energy calculations using the Generalized Solvent Boundary Potential (GSBP) and periodic boundary condition: a comparative analysis using ion solvation and oxidation free energy in proteins.

    PubMed

    Lu, Xiya; Cui, Qiang

    2013-02-21

    Free energy simulations using a finite sphere boundary condition rather than a periodic boundary condition (PBC) are attractive in the study of very large biomolecular systems. To understand the quantitative impact of various approximations in such simulations, we compare charging free energies in both solution and protein systems calculated in a linear response framework with the Generalized Solvent Boundary Potential (GSBP) and PBC simulations. For simple ions in solution, we find good agreements between GSBP and PBC charging free energies, once the relevant correction terms are taken into consideration. For PBC simulations with the particle-mesh-Ewald for long-range electrostatics, the contribution (ΔG(P-M)) due to the use of a particle rather than molecule based summation scheme in real space is found to be significant, as pointed out by Hünenberger and co-workers. For GSBP, when the inner region is close to be charge neutral, the key correction is the overpolarization of water molecules at the inner/outer dielectric boundary; the magnitude of the correction (ΔG(s-pol)), however, is relatively small. For charging (oxidation) free energy in proteins, the situation is more complex, although good agreement between GSBP and PBC can still be obtained when care is exercised. The smooth dielectric boundary approximation inherent to GSBP tends to make significant errors when the inner region is featured with a high net charge. However, the error can be corrected with Poisson-Boltzmann calculations using snapshots from GSBP simulations in a straightforward and robust manner. Because of the more complex charge and solvent distributions, the magnitudes of ΔG(P-M) and ΔG(s-pol) in protein simulations appear to be different from those derived for solution simulations, leading to uncertainty in directly comparing absolute charging free energies from PBC and GSBP simulations for protein systems. The relative charging/oxidation free energies, however, are robust. With the

  6. Consistency between kinetics and thermodynamics: general scaling conditions for reaction rates of nonlinear chemical systems without constraints far from equilibrium.

    PubMed

    Vlad, Marcel O; Popa, Vlad T; Ross, John

    2011-02-01

    We examine the problem of consistency between the kinetic and thermodynamic descriptions of reaction networks. We focus on reaction networks with linearly dependent (but generally kinetically independent) reactions for which only some of the stoichiometric vectors attached to the different reactions are linearly independent. We show that for elementary reactions without constraints preventing the system from approaching equilibrium there are general scaling relations for nonequilibrium rates, one for each linearly dependent reaction. These scaling relations express the ratios of the forward and backward rates of the linearly dependent reactions in terms of products of the ratios of the forward and backward rates of the linearly independent reactions raised to different scaling powers; the scaling powers are elements of the transformation matrix, which relates the linearly dependent stoichiometric vectors to the linearly independent stoichiometric vectors. These relations are valid for any network of elementary reactions without constraints, linear or nonlinear kinetics, far from equilibrium or close to equilibrium. We show that similar scaling relations for the reaction routes exist for networks of nonelementary reactions described by the Horiuti-Temkin theory of reaction routes where the linear dependence of the mechanistic (elementary) reactions is transferred to the overall (route) reactions. However, in this case, the scaling conditions are valid only at the steady state. General relationships between reaction rates of the two levels of description are presented. These relationships are illustrated for a specific complex reaction: radical chlorination of ethylene.

  7. Parametrization of 2,2,2-trifluoroethanol based on the generalized AMBER force field provides realistic agreement between experimental and calculated properties of pure liquid as well as water-mixed solutions.

    PubMed

    Vymětal, Jiří; Vondrášek, Jiří

    2014-09-01

    We present a novel force field model of 2,2,2-trifluoroethanol (TFE) based on the generalized AMBER force field. The model was exhaustively parametrized to reproduce liquid-state properties of pure TFE, namely, density, enthalpy of vaporization, self-diffusion coefficient, and population of trans and gauche conformers. The model predicts excellently other liquid-state properties such as shear viscosity, thermal expansion coefficient, and isotropic compressibility. The resulting model describes unexpectedly well the state equation of the liquid region in the range of 100 K and 10 MPa. More importantly, the proposed TFE model was optimized for use in combination with the TIP4P/Ew and TIP4P/2005 water models. It does not manifest excessive aggregation, which is known for other models, and therefore, it is supposed to more realistically describe the behavior of TFE/water mixtures. This was demonstrated by means of the Kirkwood-Buff theory of solutions and reasonable agreement with experimental data. We explored a considerable part of the parameter space and systematically tested individual combinations of parameters for performance in combination with the TIP4P/Ew and TIP4P/2005 water models. We observed ambiguity in parameters describing pure liquid TFE; however, most of them failed for TFE/water mixtures. We clearly demonstrated the necessity for balanced TFE-TFE, TFE-water, and water-water interactions which can be acquired only by employing implicit polarization correction in the course of parametrization.

  8. Satellite-based characterization of climatic conditions before large-scale general flowering events in Peninsular Malaysia.

    PubMed

    Azmy, Muna Maryam; Hashim, Mazlan; Numata, Shinya; Hosaka, Tetsuro; Noor, Nur Supardi Md; Fletcher, Christine

    2016-01-01

    General flowering (GF) is a unique phenomenon wherein, at irregular intervals, taxonomically diverse trees in Southeast Asian dipterocarp forests synchronize their reproduction at the community level. Triggers of GF, including drought and low minimum temperatures a few months previously has been limitedly observed across large regional scales due to lack of meteorological stations. Here, we aim to identify the climatic conditions that trigger large-scale GF in Peninsular Malaysia using satellite sensors, Tropical Rainfall Measuring Mission (TRMM) and Moderate Resolution Imaging Spectroradiometer (MODIS), to evaluate the climatic conditions of focal forests. We observed antecedent drought, low temperature and high photosynthetic radiation conditions before large-scale GF events, suggesting that large-scale GF events could be triggered by these factors. In contrast, we found higher-magnitude GF in forests where lower precipitation preceded large-scale GF events. GF magnitude was also negatively influenced by land surface temperature (LST) for a large-scale GF event. Therefore, we suggest that spatial extent of drought may be related to that of GF forests, and that the spatial pattern of LST may be related to that of GF occurrence. With significant new findings and other results that were consistent with previous research we clarified complicated environmental correlates with the GF phenomenon. PMID:27561887

  9. Satellite-based characterization of climatic conditions before large-scale general flowering events in Peninsular Malaysia

    PubMed Central

    Azmy, Muna Maryam; Hashim, Mazlan; Numata, Shinya; Hosaka, Tetsuro; Noor, Nur Supardi Md.; Fletcher, Christine

    2016-01-01

    General flowering (GF) is a unique phenomenon wherein, at irregular intervals, taxonomically diverse trees in Southeast Asian dipterocarp forests synchronize their reproduction at the community level. Triggers of GF, including drought and low minimum temperatures a few months previously has been limitedly observed across large regional scales due to lack of meteorological stations. Here, we aim to identify the climatic conditions that trigger large-scale GF in Peninsular Malaysia using satellite sensors, Tropical Rainfall Measuring Mission (TRMM) and Moderate Resolution Imaging Spectroradiometer (MODIS), to evaluate the climatic conditions of focal forests. We observed antecedent drought, low temperature and high photosynthetic radiation conditions before large-scale GF events, suggesting that large-scale GF events could be triggered by these factors. In contrast, we found higher-magnitude GF in forests where lower precipitation preceded large-scale GF events. GF magnitude was also negatively influenced by land surface temperature (LST) for a large-scale GF event. Therefore, we suggest that spatial extent of drought may be related to that of GF forests, and that the spatial pattern of LST may be related to that of GF occurrence. With significant new findings and other results that were consistent with previous research we clarified complicated environmental correlates with the GF phenomenon. PMID:27561887

  10. Satellite-based characterization of climatic conditions before large-scale general flowering events in Peninsular Malaysia

    NASA Astrophysics Data System (ADS)

    Azmy, Muna Maryam; Hashim, Mazlan; Numata, Shinya; Hosaka, Tetsuro; Noor, Nur Supardi Md.; Fletcher, Christine

    2016-08-01

    General flowering (GF) is a unique phenomenon wherein, at irregular intervals, taxonomically diverse trees in Southeast Asian dipterocarp forests synchronize their reproduction at the community level. Triggers of GF, including drought and low minimum temperatures a few months previously has been limitedly observed across large regional scales due to lack of meteorological stations. Here, we aim to identify the climatic conditions that trigger large-scale GF in Peninsular Malaysia using satellite sensors, Tropical Rainfall Measuring Mission (TRMM) and Moderate Resolution Imaging Spectroradiometer (MODIS), to evaluate the climatic conditions of focal forests. We observed antecedent drought, low temperature and high photosynthetic radiation conditions before large-scale GF events, suggesting that large-scale GF events could be triggered by these factors. In contrast, we found higher-magnitude GF in forests where lower precipitation preceded large-scale GF events. GF magnitude was also negatively influenced by land surface temperature (LST) for a large-scale GF event. Therefore, we suggest that spatial extent of drought may be related to that of GF forests, and that the spatial pattern of LST may be related to that of GF occurrence. With significant new findings and other results that were consistent with previous research we clarified complicated environmental correlates with the GF phenomenon.

  11. Satellite-based characterization of climatic conditions before large-scale general flowering events in Peninsular Malaysia.

    PubMed

    Azmy, Muna Maryam; Hashim, Mazlan; Numata, Shinya; Hosaka, Tetsuro; Noor, Nur Supardi Md; Fletcher, Christine

    2016-08-26

    General flowering (GF) is a unique phenomenon wherein, at irregular intervals, taxonomically diverse trees in Southeast Asian dipterocarp forests synchronize their reproduction at the community level. Triggers of GF, including drought and low minimum temperatures a few months previously has been limitedly observed across large regional scales due to lack of meteorological stations. Here, we aim to identify the climatic conditions that trigger large-scale GF in Peninsular Malaysia using satellite sensors, Tropical Rainfall Measuring Mission (TRMM) and Moderate Resolution Imaging Spectroradiometer (MODIS), to evaluate the climatic conditions of focal forests. We observed antecedent drought, low temperature and high photosynthetic radiation conditions before large-scale GF events, suggesting that large-scale GF events could be triggered by these factors. In contrast, we found higher-magnitude GF in forests where lower precipitation preceded large-scale GF events. GF magnitude was also negatively influenced by land surface temperature (LST) for a large-scale GF event. Therefore, we suggest that spatial extent of drought may be related to that of GF forests, and that the spatial pattern of LST may be related to that of GF occurrence. With significant new findings and other results that were consistent with previous research we clarified complicated environmental correlates with the GF phenomenon.

  12. Agreement, Shells, and Focus.

    ERIC Educational Resources Information Center

    Simpson, Andrew; Wu, Zoe

    2002-01-01

    Reconsiders development and licensing of agreement as a syntactic projection and argues for a productive developmental relation between agreement and the category of focus. Suggests that focus projections are initially selected by a variety of functional heads with real semantic content, then, over time decays into a simple concord shell. Upon…

  13. Non-Proliferation Agreements.

    ERIC Educational Resources Information Center

    Swalec, John J.

    1981-01-01

    Discusses five kinds of cooperative agreements established by the College of Lake County (IL): those with other community colleges/technical institutes; the military; business, industry, and organizations; secondary schools; and community and special interest groups. Pays particular attention to two kinds of agreements with other colleges. (CAM)

  14. Cooperative Agreements Study Report.

    ERIC Educational Resources Information Center

    Lawton, R. E.; Magruder, D.

    During the 1983 meeting of the Florida Legislature, action was taken to begin a systematic study of the level of cooperation between the Florida public schools K-12 program and the community and junior colleges. The goals and objectives of the Cooperative Agreements Study were to review and compile a list of the cooperative agreements and identify…

  15. The Helsinki Agreement

    ERIC Educational Resources Information Center

    Babel: Journal of the Australian Federation of Modern Language Teachers' Associations, 1977

    1977-01-01

    A reprint of sections of the Helsinki agreement dealing with foreign languages and civilization, and cooperation and exchanges in the field of education. The agreement supports wider knowledge of foreign languages and promotes exchanges, cooperation, lexicography, and specialized programs in adult education. (AMH)

  16. Examining General Versus Condition-Specific Health-Related Quality of Life Across Weight Categories in an Adolescent Sample.

    PubMed

    Dalton, Autumn G; Smith, Courtney; Dalton Iii, William T; Slawson, Deborah L

    2015-01-01

    This study examined health-related quality of life (HRQoL) across weight categories in adolescents using both a general and a condition-specific measure sensitive to fatigue symptoms. Participants (N = 918) completed the Pediatric Quality of Life (PedsQL) Inventory and PedsQL Multidimensional Fatigue Scale measures. Actual height and weight were used to calculate body mass index for age and sex percentiles and assign weight categories. No interaction effects between total HRQoL and weight category and gender were found; however, main effects were found for both weight category and gender. Future research should examine the impact of using different measures to assess HRQoL outcomes across weight categories.

  17. Shannon's, mutual, conditional and joint entropy information indices: generalization of global indices defined from local vertex invariants.

    PubMed

    Barigye, Stephen J; Marrero-Ponce, Yovani; Santiago, Oscar Martinez; López, Yoan Martinez; Pérez-Giménez, Facundo; Torrens, Francisco

    2013-06-01

    A new mathematical approach is proposed in the definition of molecular descriptors (MDs) based on the application of information theory concepts. This approach stems from a new matrix representation of a molecular graph (G) which is derived from the generalization of an incidence matrix whose row entries correspond to connected subgraphs of a given G, and the calculation of the Shannon's entropy, the negentropy and the standardized information content, plus for the first time, the mutual, conditional and joint entropy-based MDs associated with G. We also define strategies that generalize the definition of global or local invariants from atomic contributions (local vertex invariants, LOVIs), introducing related metrics (norms), means and statistical invariants. These invariants are applied to a vector whose components express the atomic information content calculated using the Shannon's, mutual, conditional and joint entropybased atomic information indices. The novel information indices (IFIs) are implemented in the program TOMOCOMDCARDD. A principal component analysis reveals that the novel IFIs are capable of capturing structural information not codified by IFIs implemented in the software DRAGON. A comparative study of the different parameters (e.g. subgraph orders and/or types, invariants and class of MDs) used in the definition of these IFIs reveals several interesting results. The mutual entropy-based indices give the best correlation results in modeling of a physicochemical property, namely the partition coefficient of the 34 derivatives of 2-furylethylenes, among the classes of indices investigated in this study. In a comparison with classical MDs it is demonstrated that the new IFIs give good results for various QSPR models.

  18. 48 CFR 49.109 - Settlement agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Settlement agreements. 49.109 Section 49.109 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS General Principles 49.109 Settlement agreements....

  19. 14 CFR 141.26 - Training agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Training agreements. 141.26 Section 141.26... OTHER CERTIFICATED AGENCIES PILOT SCHOOLS General § 141.26 Training agreements. A training center certificated under part 142 of this chapter may provide the training, testing, and checking for pilot...

  20. 14 CFR 142.33 - Training agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Training agreements. 142.33 Section 142.33... OTHER CERTIFICATED AGENCIES TRAINING CENTERS General § 142.33 Training agreements. A pilot school certificated under part 141 of this chapter may provide training, testing, and checking for a training...

  1. 26 CFR 601.802 - Cooperative agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... STATEMENT OF PROCEDURAL RULES Tax Counseling for the Elderly § 601.802 Cooperative agreements. (a) General. Tax Counseling for the Elderly programs will be administered by sponsor organizations under... agreements. If appropriations to implement the Tax Counseling for the Elderly program are received at a...

  2. 26 CFR 601.802 - Cooperative agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... STATEMENT OF PROCEDURAL RULES Tax Counseling for the Elderly § 601.802 Cooperative agreements. (a) General. Tax Counseling for the Elderly programs will be administered by sponsor organizations under... agreements. If appropriations to implement the Tax Counseling for the Elderly program are received at a...

  3. 26 CFR 601.802 - Cooperative agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... STATEMENT OF PROCEDURAL RULES Tax Counseling for the Elderly § 601.802 Cooperative agreements. (a) General. Tax Counseling for the Elderly programs will be administered by sponsor organizations under... agreements. If appropriations to implement the Tax Counseling for the Elderly program are received at a...

  4. 26 CFR 601.202 - Closing agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 20 2013-04-01 2013-04-01 false Closing agreements. 601.202 Section 601.202 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INTERNAL REVENUE PRACTICE STATEMENT OF PROCEDURAL RULES Rulings and Other Specific Matters § 601.202 Closing agreements. (a) General. (1) Under section 7121 of the...

  5. 24 CFR 280.30 - Grant agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Grant agreement. 280.30 Section 280... DEVELOPMENT GRANT PROGRAMS NEHEMIAH HOUSING OPPORTUNITY GRANTS PROGRAM Program Operation § 280.30 Grant agreement. (a) General. The recipient's responsibilities under NHOP will be incorporated in a...

  6. 24 CFR 280.30 - Grant agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Grant agreement. 280.30 Section 280... DEVELOPMENT GRANT PROGRAMS NEHEMIAH HOUSING OPPORTUNITY GRANTS PROGRAM Program Operation § 280.30 Grant agreement. (a) General. The recipient's responsibilities under NHOP will be incorporated in a...

  7. 24 CFR 280.30 - Grant agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Grant agreement. 280.30 Section 280... DEVELOPMENT GRANT PROGRAMS NEHEMIAH HOUSING OPPORTUNITY GRANTS PROGRAM Program Operation § 280.30 Grant agreement. (a) General. The recipient's responsibilities under NHOP will be incorporated in a...

  8. 26 CFR 601.202 - Closing agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 20 2014-04-01 2014-04-01 false Closing agreements. 601.202 Section 601.202 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INTERNAL REVENUE PRACTICE STATEMENT OF PROCEDURAL RULES Rulings and Other Specific Matters § 601.202 Closing agreements. (a) General. (1) Under section 7121 of the...

  9. 30 CFR 208.9 - Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Agreements. 208.9 Section 208.9 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT SALE OF FEDERAL ROYALTY OIL General Provisions § 208.9 Agreements. (a) A purchaser must submit to MMS two...

  10. Ionospheric data assimilation with thermosphere-ionosphere-electrodynamics general circulation model and GPS-TEC during geomagnetic storm conditions

    NASA Astrophysics Data System (ADS)

    Chen, C. H.; Lin, C. H.; Matsuo, T.; Chen, W. H.; Lee, I. T.; Liu, J. Y.; Lin, J. T.; Hsu, C. T.

    2016-06-01

    The main purpose of this paper is to investigate the effects of rapid assimilation-forecast cycling on the performance of ionospheric data assimilation during geomagnetic storm conditions. An ensemble Kalman filter software developed by the National Center for Atmospheric Research (NCAR), called Data Assimilation Research Testbed, is applied to assimilate ground-based GPS total electron content (TEC) observations into a theoretical numerical model of the thermosphere and ionosphere (NCAR thermosphere-ionosphere-electrodynamics general circulation model) during the 26 September 2011 geomagnetic storm period. Effects of various assimilation-forecast cycle lengths: 60, 30, and 10 min on the ionospheric forecast are examined by using the global root-mean-squared observation-minus-forecast (OmF) TEC residuals. Substantial reduction in the global OmF for the 10 min assimilation-forecast cycling suggests that a rapid cycling ionospheric data assimilation system can greatly improve the quality of the model forecast during geomagnetic storm conditions. Furthermore, updating the thermospheric state variables in the coupled thermosphere-ionosphere forecast model in the assimilation step is an important factor in improving the trajectory of model forecasting. The shorter assimilation-forecast cycling (10 min in this paper) helps to restrain unrealistic model error growth during the forecast step due to the imbalance among model state variables resulting from an inadequate state update, which in turn leads to a greater forecast accuracy.

  11. Cross-sectional survey of older patients' views regarding multidisciplinary care for chronic conditions in general practice.

    PubMed

    Bonney, Andrew; Magee, Christopher; Pearson, Russell

    2014-01-01

    The ageing population and increasing prevalence of chronic illness have contributed to the need for significant primary care reform, including increased use of multidisciplinary care and task substitution. This cross-sectional study explores conditions under which older patients would accept having health professionals other than their general practitioner (GP) involved in their care for chronic disease management (CDM). Ten practices were randomly sampled from a contiguous major city and inner regional area. Questionnaires were distributed to consecutive patients aged 60 years and over in each practice. Agency theory was used to inform analyses. Statistical analysis was undertaken using Wald's test, growth modelling and linear regression, controlling for the clustered design. The response rate was 53% (n=272). Most respondents (79%) had at least one chronic health condition. Respondents were more comfortable with GP than with practice nurse management in the CDM scenario (Wald's test=105.49, P<0.001). Comfort with practice nurse CDM was positively associated with increased contact with their GP at the time of the visit (β=0.41, P<0.001), negatively associated with the number of the respondent's chronic conditions (β=-0.13, P=0.030) and not associated with the frequency of other health professional visits. Agency theory suggests that patients employ continuity of care to optimise factors important in CDM: information symmetry and goal alignment. Our findings are consistent with the theory and lend support to ensuring that interpersonal continuity of care is not lost in health care reform. Further research exploring patients' acceptance of differing systems of care is required.

  12. Industry Agreement Acts and environmental management in Australia

    NASA Astrophysics Data System (ADS)

    Hollick, Malcolm

    1983-05-01

    In Australia many major developments are authorized by agreements negotiated between companies and the state government and ratified by Parliament as Agreement Acts The means by which these are negotiated and ratified, their terms, and their legal status are thus of great importance to Australian resource and environmental management These aspects are examined, revealing a lessening of the tendency to provide special rights and privileges and a trend towards the inclusion of more resource and environmental management provisions in the Acts It is argued that major developments require special conditions beyond the scope of general laws in order to control their social and environmental side effects, and that Agreements Acts could be a valuable means to this end Ways of improving them from this point of view are discussed

  13. 29 CFR 215.6 - The Model Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 2 2014-07-01 2014-07-01 false The Model Agreement. 215.6 Section 215.6 Labor Regulations...), FEDERAL TRANSIT LAW § 215.6 The Model Agreement. The Model (or National) Agreement mentioned in paragraphs... agreement provides fair and equitable arrangements to protect the interests of employees in general...

  14. 29 CFR 215.6 - The Model Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 2 2013-07-01 2013-07-01 false The Model Agreement. 215.6 Section 215.6 Labor Regulations...), FEDERAL TRANSIT LAW § 215.6 The Model Agreement. The Model (or National) Agreement mentioned in paragraphs... agreement provides fair and equitable arrangements to protect the interests of employees in general...

  15. 29 CFR 215.6 - The Model Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 2 2012-07-01 2012-07-01 false The Model Agreement. 215.6 Section 215.6 Labor Regulations...), FEDERAL TRANSIT LAW § 215.6 The Model Agreement. The Model (or National) Agreement mentioned in paragraphs... agreement provides fair and equitable arrangements to protect the interests of employees in general...

  16. 29 CFR 215.6 - The Model Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 2 2011-07-01 2011-07-01 false The Model Agreement. 215.6 Section 215.6 Labor Regulations...), FEDERAL TRANSIT LAW § 215.6 The Model Agreement. The Model (or National) Agreement mentioned in paragraphs... agreement provides fair and equitable arrangements to protect the interests of employees in general...

  17. 32 CFR 21.680 - Technology investment agreements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... assistance transaction. Technology investment agreements are described more fully in 32 CFR part 37. ... 32 National Defense 1 2011-07-01 2011-07-01 false Technology investment agreements. 21.680 Section... AGREEMENT REGULATIONS DoD GRANTS AND AGREEMENTS-GENERAL MATTERS Definitions § 21.680 Technology...

  18. 32 CFR 21.680 - Technology investment agreements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... assistance transaction. Technology investment agreements are described more fully in 32 CFR part 37. ... 32 National Defense 1 2014-07-01 2014-07-01 false Technology investment agreements. 21.680 Section... AGREEMENT REGULATIONS DoD GRANTS AND AGREEMENTS-GENERAL MATTERS Definitions § 21.680 Technology...

  19. 32 CFR 21.680 - Technology investment agreements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... assistance transaction. Technology investment agreements are described more fully in 32 CFR part 37. ... 32 National Defense 1 2013-07-01 2013-07-01 false Technology investment agreements. 21.680 Section... AGREEMENT REGULATIONS DoD GRANTS AND AGREEMENTS-GENERAL MATTERS Definitions § 21.680 Technology...

  20. 32 CFR 21.680 - Technology investment agreements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... assistance transaction. Technology investment agreements are described more fully in 32 CFR part 37. ... 32 National Defense 1 2012-07-01 2012-07-01 false Technology investment agreements. 21.680 Section... AGREEMENT REGULATIONS DoD GRANTS AND AGREEMENTS-GENERAL MATTERS Definitions § 21.680 Technology...

  1. 32 CFR 21.680 - Technology investment agreements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... assistance transaction. Technology investment agreements are described more fully in 32 CFR part 37. ... 32 National Defense 1 2010-07-01 2010-07-01 false Technology investment agreements. 21.680 Section... AGREEMENT REGULATIONS DoD GRANTS AND AGREEMENTS-GENERAL MATTERS Definitions § 21.680 Technology...

  2. Timoshenko beam-column with generalized end conditions on elastic foundation: Dynamic-stiffness matrix and load vector

    NASA Astrophysics Data System (ADS)

    Arboleda-Monsalve, Luis G.; Zapata-Medina, David G.; Aristizabal-Ochoa, J. Darío

    2008-03-01

    The dynamic-stiffness matrix and load vector of a Timoshenko beam-column resting on a two-parameter elastic foundation with generalized end conditions are presented. The proposed model includes the frequency effects on the stiffness matrix and load vector as well as the coupling effects of: (1) bending and shear deformations along the member; (2) translational and rotational lumped masses at both ends; (3) translational and rotational masses uniformly distributed along its span; (3) axial load (tension or compression) applied at both ends; and (4) shear forces along the span induced by the applied axial load as the beam deforms according to the "modified shear equation" proposed by Timoshenko. The dynamic analyses of framed structures can be performed by including the effects of the imposed frequency ( ω>0) on the dynamic-stiffness matrix and load vector while the static and stability analyses can be carried out by making the frequency ω=0. The proposed model and corresponding dynamic-stiffness matrix and load vector represent a general solution capable to solve, just by using a single segment per element, the static, dynamic and stability analyses of any elastic framed structure made of prismatic beam-columns with semi-rigid connections resting on two-parameter elastic foundations. Analytical results indicate that the elastic behavior of framed structures made of beam-columns is frequency dependent and highly sensitive to the coupling effects just mentioned. Three comprehensive examples are presented to show the capacities and validity of the proposed method and the obtained results are compared with the finite element method and other analytical approaches.

  3. Expected changes in future agro-climatological conditions in Northeast Thailand and their differences between general circulation models

    NASA Astrophysics Data System (ADS)

    Masaki, Yoshimitsu; Ishigooka, Yasushi; Kuwagata, Tsuneo; Goto, Shinkichi; Sawano, Shinji; Hasegawa, Toshihiro

    2011-12-01

    We have studied future changes in the atmospheric and hydrological environments in Northeast Thailand from the viewpoint of risk assessment of future cultural environments in crop fields. To obtain robust and reliable estimation for future climate, ten general circulation models under three warming scenarios, B1, A1B, and A2, were used in this study. The obtained change trends show that daily maximum air temperature and precipitation will increase by 2.6°C and 4.0%, respectively, whereas soil moisture will decrease by c.a. 1% point in volumetric water content at the end of this century under the A1B scenario. Seasonal contrasts in precipitation will intensify: precipitation increases in the rainy season and precipitation decreases in the dry season. Soil moisture will slightly decrease almost throughout the year. Despite a homogeneous increase in the air temperature over Northeast Thailand, a future decrease in soil water content will show a geographically inhomogeneous distribution: Soil will experience a relative larger decrease in wetness at a shallow depth on the Khorat plateau than in the surrounding mountainous area, reflecting vegetation cover and soil texture. The predicted increase in air temperature is relatively consistent between general circulation models. In contrast, relatively large intermodel differences in precipitation, especially in long-term trends, produce unwanted bias errors in the estimation of other hydrological elements, such as soil moisture and evaporation, and cause uncertainties in projection of the agro-climatological environment. Offline hydrological simulation with a wide precipitation range is one strategy to compensate for such uncertainties and to obtain reliable risk assessment of future cultural conditions in rainfed paddy fields in Northeast Thailand.

  4. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... acquisitions, including hardship acquisition and protective buying (see 23 CFR 710.503). The STD must prepare a project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on an..., donations, or other contributions applied to the project provided conditions in 23 U.S.C. 323 and 23 CFR...

  5. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... acquisitions, including hardship acquisition and protective buying (see 23 CFR 710.503). The STD must prepare a project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on an..., donations, or other contributions applied to the project provided conditions in 23 U.S.C. 323 and 23 CFR...

  6. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... acquisitions, including hardship acquisition and protective buying (see 23 CFR 710.503). The STD must prepare a project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on an..., donations, or other contributions applied to the project provided conditions in 23 U.S.C. 323 and 23 CFR...

  7. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... acquisitions, including hardship acquisition and protective buying (see 23 CFR 710.503). The STD must prepare a project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on an..., donations, or other contributions applied to the project provided conditions in 23 U.S.C. 323 and 23 CFR...

  8. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... acquisitions, including hardship acquisition and protective buying (see 23 CFR 710.503). The STD must prepare a project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on an..., donations, or other contributions applied to the project provided conditions in 23 U.S.C. 323 and 23 CFR...

  9. 12 CFR 1807.900 - Assistance agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 7 2011-01-01 2011-01-01 false Assistance agreement. 1807.900 Section 1807.900 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY CAPITAL MAGNET FUND Terms and Conditions of Assistance § 1807.900 Assistance agreement. (a) Each Applicant...

  10. 12 CFR 1807.900 - Assistance agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 9 2012-01-01 2012-01-01 false Assistance agreement. 1807.900 Section 1807.900 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY CAPITAL MAGNET FUND Terms and Conditions of Assistance § 1807.900 Assistance agreement. (a) Each Applicant...

  11. 12 CFR 1807.900 - Assistance agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Assistance agreement. 1807.900 Section 1807.900 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY CAPITAL MAGNET FUND Terms and Conditions of Assistance § 1807.900 Assistance agreement. (a) Each...

  12. 12 CFR 1807.900 - Assistance agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 9 2013-01-01 2013-01-01 false Assistance agreement. 1807.900 Section 1807.900 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY CAPITAL MAGNET FUND Terms and Conditions of Assistance § 1807.900 Assistance agreement. (a) Each Applicant...

  13. Glutamic acid decarboxylase 65: a link between GABAergic synaptic plasticity in the lateral amygdala and conditioned fear generalization.

    PubMed

    Lange, Maren D; Jüngling, Kay; Paulukat, Linda; Vieler, Marc; Gaburro, Stefano; Sosulina, Ludmila; Blaesse, Peter; Sreepathi, Hari K; Ferraguti, Francesco; Pape, Hans-Christian

    2014-08-01

    An imbalance of the gamma-aminobutyric acid (GABA) system is considered a major neurobiological pathomechanism of anxiety, and the amygdala is a key brain region involved. Reduced GABA levels have been found in anxiety patients, and genetic variations of glutamic acid decarboxylase (GAD), the rate-limiting enzyme of GABA synthesis, have been associated with anxiety phenotypes in both humans and mice. These findings prompted us to hypothesize that a deficiency of GAD65, the GAD isoform controlling the availability of GABA as a transmitter, affects synaptic transmission and plasticity in the lateral amygdala (LA), and thereby interferes with fear responsiveness. Results indicate that genetically determined GAD65 deficiency in mice is associated with (1) increased synaptic length and release at GABAergic connections, (2) impaired efficacy of GABAergic synaptic transmission and plasticity, and (3) reduced spillover of GABA to presynaptic GABAB receptors, resulting in a loss of the associative nature of long-term synaptic plasticity at cortical inputs to LA principal neurons. (4) In addition, training with high shock intensities in wild-type mice mimicked the phenotype of GAD65 deficiency at both the behavioral and synaptic level, indicated by generalization of conditioned fear and a loss of the associative nature of synaptic plasticity in the LA. In conclusion, GAD65 is required for efficient GABAergic synaptic transmission and plasticity, and for maintaining extracellular GABA at a level needed for associative plasticity at cortical inputs in the LA, which, if disturbed, results in an impairment of the cue specificity of conditioned fear responses typifying anxiety disorders.

  14. Joint envelope and frequency order spectrum analysis based on iterative generalized demodulation for planetary gearbox fault diagnosis under nonstationary conditions

    NASA Astrophysics Data System (ADS)

    Feng, Zhipeng; Chen, Xiaowang; Liang, Ming

    2016-08-01

    Planetary gearbox vibration signals under nonstationary conditions are characterized by time-varying nature and complex multi-components, making it very difficult to extract features for fault diagnosis. Order spectrum analysis is one of the effective approaches for nonstationary signal analysis of rotating machinery. The main idea of order analysis is to map the time-varying frequency components into constant ones. Inspired by this idea, we propose a new order spectrum analysis method to exploit the unique property of iterative generalized demodulation in converting arbitrary instantaneous frequency trajectories of multi-component signals into constant frequency lines on the time-frequency plane. This new method is completely algorithm-based and tachometer/encoder-free, thus easy to implement. It does not involve equi-angular resampling commonly required by most order tracking methods and is hence free from the decimation and/or interpolation error. The proposed order analysis method can eliminate the time-variation effect of frequency and thus can effectively reveal the harmonic order constituents of nonstationary multi-component signals. However, the planetary gearbox vibration signals also lead to complex sideband orders. As such, we further propose to analyze the order spectrum of amplitude envelope. This will eliminate the complex sideband orders in the order spectrum of original signals, leading to a substantially simplified and more reliable gear characteristic frequency identification process. Nevertheless, the gear and/or planet carrier rotating frequency orders, which are irrelevant to gear fault, may still exist. To avoid possible misleading results due to such frequency orders, we also propose to analyze the order spectrum of instantaneous frequency. Theoretically, the peaks present in frequency order spectrum directly correspond to the gear characteristic frequency orders, which can be used to extract gear fault signature more explicitly. The proposed

  15. Time-frequency demodulation analysis based on iterative generalized demodulation for fault diagnosis of planetary gearbox under nonstationary conditions

    NASA Astrophysics Data System (ADS)

    Feng, Zhipeng; Chen, Xiaowang; Liang, Ming; Ma, Fei

    2015-10-01

    The vibration signal of planetary gearboxes exhibits the characteristics of both amplitude modulation (AM) and frequency modulation (FM), and thus has a complex sideband structure. Time-varying speed and/or load will result in time variant characteristic frequency components. Since the modulating frequency is related to the gear fault characteristic frequency, the AM and FM parts each alone contains the information of the gear fault. We propose a time-frequency amplitude and frequency demodulation analysis metbhod to avoid the complex time-variant sideband analysis, and thereby identify the time-variant gear fault characteristic frequency. We enhance the time-frequency analysis via iterative generalized demodulation (IGD). The time-varying amplitude and frequency demodulated spectra have fine time-frequency resolution and are free of cross term interferences. They do not involve complex time-variant sidebands, thus considerably facilitating fault diagnosis of planetary gearboxes under nonstationary conditions. The method is validated using both numerically simulated data and experimental signals.

  16. Ultrafine particle concentrations in the surroundings of an urban area: comparing downwind to upwind conditions using Generalized Additive Models (GAMs).

    PubMed

    Sartini, Claudio; Zauli Sajani, Stefano; Ricciardelli, Isabella; Delgado-Saborit, Juana Mari; Scotto, Fabiana; Trentini, Arianna; Ferrari, Silvia; Poluzzi, Vanes

    2013-10-01

    The aim of this study was to investigate the influence of an urban area on ultrafine particle (UFP) concentration in nearby surrounding areas. We assessed how downwind and upwind conditions affect the UFP concentration at a site placed a few kilometres from the city border. Secondarily, we investigated the relationship among other meteorological factors, temporal variables and UFP. Data were collected for 44 days during 2008 and 2009 at a rural site placed about 3 kilometres from Bologna, in northern Italy. Measurements were performed using a spectrometer (FMPS TSI 3091). The average UFP number concentration was 11 776 (±7836) particles per cm(3). We analysed the effect of wind direction in a multivariate Generalized Additive Model (GAM) adjusted for the principal meteorological parameters and temporal trends. An increase of about 25% in UFP levels was observed when the site was downwind of the urban area, compared with the levels observed when wind blew from rural areas. The size distribution of particles was also affected by the wind direction, showing higher concentration of small size particles when the wind blew from the urban area. The GAM showed a good fit to the data (R(2) = 0.81). Model choice was via Akaike Information Criteria (AIC). The analysis also revealed that an approach based on meteorological data plus temporal trends improved the goodness of the fit of the model. In addition, the findings contribute to evidence on effects of exposure to ultrafine particles on a population living in city surroundings. PMID:24077061

  17. 45 CFR 1640.3 - Contractual agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OF FEDERAL LAW TO LSC RECIPIENTS § 1640.3 Contractual agreement. As a condition of receiving LSC... respect to its LSC funds, it will be subject to the Federal laws listed in § 1640.2(a)(1). The...

  18. Making the best of corporate integrity agreements.

    PubMed

    Henderson, W M; Imperato, G L

    2001-07-01

    Corporate integrity agreements (CIAs) imposed by the Office of Inspector General (OIG) of HHS have increased dramatically in the past five years. Healthcare organizations that enter into a CIA face burdensome monitoring and reporting requirements. However, it may be possible to lessen these burdens by negotiating modifications to the CIA's requirements. Organizations that have compliance programs in place can negotiate with the OIG to integrate elements of their existing compliance programs into the CIA. The organization also should attempt to negotiate limiting the scope of the monitoring to include only the area that was originally investigated. In addition, it may be valuable to negotiate insertion of a clause in the CIA allowing the organization to request renegotiation of the terms and duration of certain elements of the agreement after the first year, if conditions are met. An organized CIA negotiation process may be valuable in obtaining a reduced scope of the procedures required by the CIA and preparing the organization to meet its obligations. PMID:11467232

  19. Making the best of corporate integrity agreements.

    PubMed

    Henderson, W M; Imperato, G L

    2001-07-01

    Corporate integrity agreements (CIAs) imposed by the Office of Inspector General (OIG) of HHS have increased dramatically in the past five years. Healthcare organizations that enter into a CIA face burdensome monitoring and reporting requirements. However, it may be possible to lessen these burdens by negotiating modifications to the CIA's requirements. Organizations that have compliance programs in place can negotiate with the OIG to integrate elements of their existing compliance programs into the CIA. The organization also should attempt to negotiate limiting the scope of the monitoring to include only the area that was originally investigated. In addition, it may be valuable to negotiate insertion of a clause in the CIA allowing the organization to request renegotiation of the terms and duration of certain elements of the agreement after the first year, if conditions are met. An organized CIA negotiation process may be valuable in obtaining a reduced scope of the procedures required by the CIA and preparing the organization to meet its obligations.

  20. Non-healing foot ulcers in diabetic patients: general and local interfering conditions and management options with advanced wound dressings.

    PubMed

    Uccioli, Luigi; Izzo, Valentina; Meloni, Marco; Vainieri, Erika; Ruotolo, Valeria; Giurato, Laura

    2015-04-01

    Medical knowledge about wound management has improved as recent studies have investigated the healing process and its biochemical background. Despite this, foot ulcers remain an important clinical problem, often resulting in costly, prolonged treatment. A non-healing ulcer is also a strong risk factor for major amputation. Many factors can interfere with wound healing, including the patient's general health status (i.e., nutritional condition indicated by albumin levels) or drugs such as steroids that can interfere with normal healing. Diabetic complications (i.e., renal insufficiency) may delay healing and account for higher amputation rates observed in diabetic patients under dialysis treatment. Wound environment (e.g., presence of neuropathy, ischaemia, and infection) may significantly influence healing by interfering with the physiological healing cascade and adding local release of factors that may worsen the wound. The timely and well-orchestrated release of factors regulating the healing process, observed in acute wounds, is impaired in non-healing wounds that are blocked in a chronic inflammatory phase without progressing to healing. This chronic phase is characterised by elevated protease activity (EPA) of metalloproteinases (MMPs) and serine proteases (e.g., human neutrophil elastase) that interfere with collagen synthesis, as well as growth factor release and action. EPA (mainly MMP 9, MMP-8 and elastase) and inflammatory factors present in the wound bed (such as IL-1, IL-6, and TNFa) account for the catabolic state of non-healing ulcers. The availability of wound dressings that modulate EPA has added new therapeutic options for treating non-healing ulcers. The literature confirms advantages obtained by reducing protease activity in the wound bed, with better outcomes achieved by using these dressings compared with traditional ones. New technologies also allow a physician to know the status of the wound bed environment, particularly EPA, in a clinical

  1. Stability and free vibration analyses of an orthotropic singly symmetric Timoshenko beam-column with generalized end conditions

    NASA Astrophysics Data System (ADS)

    Monsalve-Cano, J. F.; Darío Aristizábal-Ochoa, J.

    2009-12-01

    The stability and free vibration analyses (i.e., buckling, natural frequencies and modal shapes) of an orthotropic singly symmetric 3D Timoshenko beam-column with generalized boundary conditions (i.e., with bending and torsional semirigid restraints and lateral bracings as well as lumped masses at both ends) subjected to an eccentric end axial load are presented in a classical manner. The five governing equations of dynamic equilibrium (i.e., two transverse shear equations, two bending moment equations and pure torsional moment equation) are sufficient to determine the natural frequencies and the corresponding modal shapes of the beam-column in the two principal planes of bending and torsion about its longitudinal axis. The proposed model includes the coupling effects among: (1) the deformations due to bending, shear and pure torsion; (2) inertias (translational, rotational and torsional) of all masses considered; (3) eccentric axial loads applied at the ends, and (4) restraints at the supports (bending, torsional and lateral bracings at both ends of the member). However, the effects of axial deformations and warping torsion produced by the axial load are not included; consequently the proposed model is not capable of capturing the phenomena of torsional buckling or combined lateral bending-torsional buckling. The proposed analytical model indicates that the stability and dynamic response of beam-columns are highly sensitive to the coupling effects, particularly in members with both ends free to rotate. The natural frequencies and modal shapes can be determined from the eigenvalues of a full 4×4 matrix for vibration in the plane of symmetry (using the uncoupled equations of transverse force and moment equilibrium at both ends) and from a full 6×6 matrix for the coupled shear-bending-torsional vibration (using the coupled equations of transverse shear, bending and torsional moment equilibrium at both ends). Also, it is shown that the proposed method reproduces the

  2. Agreements in Virtual Organizations

    NASA Astrophysics Data System (ADS)

    Pankowska, Malgorzata

    This chapter is an attempt to explain the important impact that contract theory delivers with respect to the concept of virtual organization. The author believes that not enough research has been conducted in order to transfer theoretical foundations for networking to the phenomena of virtual organizations and open autonomic computing environment to ensure the controllability and management of them. The main research problem of this chapter is to explain the significance of agreements for virtual organizations governance. The first part of this chapter comprises explanations of differences among virtual machines and virtual organizations for further descriptions of the significance of the first ones to the development of the second. Next, the virtual organization development tendencies are presented and problems of IT governance in highly distributed organizational environment are discussed. The last part of this chapter covers analysis of contracts and agreements management for governance in open computing environments.

  3. Countries renew rescue agreement

    NASA Astrophysics Data System (ADS)

    Bush, Susan M.

    To insure long-term continuity for the international satellite search and rescue system, COSPAS/SARSAT, an intergovernmental agreement binding the four sponsoring nations to cooperate was signed July 1 in Paris. According to Russell Vollmers of the National Oceanic and Atmospheric Administration, the agreement is binding for 15 years, with an automatic extension.The system marked the fifth anniversary of its first rescue last year, when on September 10, 1982, three persons were rescued. Begun in the 1970s by NASA as an experiment, COSPAS/SARSAT (a Russian-English acronym) is now a cooperative project among the United States, Canada, France, and the Soviet Union. Its goal is to reduce the time required to rescue air and maritime distress victims and also to locate victims who otherwise may not be found, thus using the satellite system as a life-saving device.

  4. [Innovative medicines and market access agreements].

    PubMed

    Toumi, M; Zard, J; Duvillard, R; Jommi, C

    2013-09-01

    Market Access Agreements (MAA) for drugs have emerged in response to the need to control health expenditures, as well as to the uncertainty about the true benefit of a drug. It is possible to group MAA in two types of agreements: financial agreements and outcome-based agreements. MAA is a growing trend and is shifting towards conditional access. However, the willingness to use these contracts and their implementation differ across countries, and some are still resistant to put them in place. The MAA challenges to overcome encompass the complexity of the schemes, the administrative burden and the difficulty of evaluating MAA. It is likely that these agreements might experience further evolution in the future to become a faster pathway for therapeutic innovations, at a fair price.

  5. Trade agreements on know-how discussed

    NASA Astrophysics Data System (ADS)

    Melnikov, A.

    1983-10-01

    Under the conditions of the present scientific and technical revolution the thirst for possessing advanced production experience and knowledge has led to a significant increase in the number of agreements on the transmission of know-how as compared with license agreements, whose objects are patented scientific and technical achievements. As a rule, the All-Union Litsenzintorg Association concludes agreements on the transmission of know-how in the USSR. A number of other foreign trade associations also conclude such agreements. In accordance with their charters operations are performed for the transmission of know-how, when the latter form an integral part of agreements on the export or import of goods based on the products list of these associations. An analysis of the terms of agreements on the transmission of know-how shows that the rights and duties of the parties to the agreement coincide in large measure with the rights and duties of the licensor and licensee according to the license agreement.

  6. 29 CFR Appendix B to Subpart I of... - General Testing Conditions and Additional Guidelines for Personal Fall Protection Systems (Non...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... Positioning device systems—(a) Test Conditions. (1) The fixed anchorage should be rigid and should not have a..., nor exceed 1,000 pounds (4.45 Kn) for the remainder of the arrest time. (4) All other...

  7. Endogenous Depression in the Elderly: Prevalence and Agreement among Measures.

    ERIC Educational Resources Information Center

    Gallagher-Thompson, Dolores; And Others

    1992-01-01

    Examined agreement among diagnoses made according to 5 definitions of endogenous depression in 99 depressed elders. Poor to fair agreement was generally demonstrated, except for Research Diagnostic Criteria and Diagnostic and Statistical Manual of Mental Disorders, which demonstrated excellent agreement. Mostly, demographic and clinical variables…

  8. 34 CFR 686.12 - Agreement to serve.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) GRANT PROGRAM Application Procedures § 686.12 Agreement to serve. (a) General. A student who meets the... agreement to serve. The agreement provides that, for each TEACH Grant-eligible program for which the student... enrolled in the program for which the recipient received the TEACH Grant— (i) In a low-income school;...

  9. 24 CFR 700.155 - Grant agreement and administration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Grant agreement and administration... ASSISTANCE PROGRAMS AND PUBLIC AND INDIAN HOUSING PROGRAMS) CONGREGATE HOUSING SERVICES PROGRAM § 700.155 Grant agreement and administration. (a) General. HUD will enter into grant agreements with grantees,...

  10. 24 CFR 700.155 - Grant agreement and administration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Grant agreement and administration... ASSISTANCE PROGRAMS AND PUBLIC AND INDIAN HOUSING PROGRAMS) CONGREGATE HOUSING SERVICES PROGRAM § 700.155 Grant agreement and administration. (a) General. HUD will enter into grant agreements with grantees,...

  11. 34 CFR 682.405 - Loan rehabilitation agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Loan rehabilitation agreement. 682.405 Section 682.405... Federal Family Education Loan Programs by a Guaranty Agency § 682.405 Loan rehabilitation agreement. (a) General. (1) A guaranty agency that has a basic program agreement must enter into a loan...

  12. 24 CFR 266.15 - Risk-Sharing Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Risk-Sharing Agreement. 266.15... HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS General Provisions § 266.15 Risk-Sharing Agreement. Execution of a Risk-Sharing Agreement is a prerequisite...

  13. Conditions that Promote Generalization: Suggestions to Increase the Transfer of Skills Learned in the Resource Room to the Regular Classroom.

    ERIC Educational Resources Information Center

    Schmidt, John L.

    1983-01-01

    Resource teachers can help learning disabled students generalize skills to a mainstream setting with three types of procedures: transfer activities; self control procedures (in which a behavior contract is developed and contingencies for self reinforcement are specified); and cooperative planning (in which resource teachers and regular teachers…

  14. 78 FR 5148 - Special Conditions: Embraer S.A., Model EMB-550 Airplanes; Flight Envelope Protection: General...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-24

    ... April 11, 2000 (65 FR 19477-19478), as well as at http://DocketsInfo.dot.gov/ . Docket: Background...; Flight Envelope Protection: General Limiting Requirements AGENCY: Federal Aviation Administration (FAA...(s), specifically new control architecture and a full digital flight control system which...

  15. 78 FR 31838 - Special Conditions: Embraer S.A., Model EMB-550 Airplanes; Flight Envelope Protection: General...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-28

    ... published in the Federal Register on January 24, 2013 (78 FR 5148). No comments were received, and the...; Flight Envelope Protection: General Limiting Requirements AGENCY: Federal Aviation Administration (FAA... new control architecture and a full digital flight control system which provides flight...

  16. Mixed boundary conditions in ocean general circulation models and their influence on the stability of the model`s conveyor belt

    SciTech Connect

    Mikolajewicz, U.; Maier-reimer, E.

    1994-11-01

    When driven under `mixed boundary conditions` coarse resolution ocean general circulation models (OGCMs) generally show a high sensitivity of the present-day thermohaline circulation against perturbations. We will show that an alternative formulation of the boundary condition for temperature, a mixture of prescribed heat fluxes and additional restoring of the sea surface temperature to a climatological boundary temperature with a longer time constant, drastically alters the stability of the modes of the thermohaline circulation. The results from simulations with the Hamburg large-scale geostrophic OGCM indicate that the stability of the mode of the thermohaline circulation with formation of North Atlantic deepwater increases, if the damping of sea surface temperature anomalies is reduced, whereas the opposite is true for the mode without North Atlantic deep water formation. It turns out that the formulation of the temperature boundary condition also affects the variability of the model.

  17. Matrix Norms and the Condition Number: A General Framework to Improve Mesh Quality via Node-Movement

    SciTech Connect

    KNUPP,PATRICK

    1999-09-27

    Objective functions for unstructured hexahedral and tetrahedral mesh optimization are analyzed using matrices and matrix norms. Mesh untangling objective functions that create valid meshes are used to initialize the optimization process. Several new objective functions to achieve element invertibility and quality are investigated, the most promising being the ''condition number''. The condition number of the Jacobian matrix of an element forms the basis of a barrier-based objective function that measures the distance to the set of singular matrices and has the ideal matrix as a stationary point. The method was implemented in the Cubit code, with promising results.

  18. Validity of generalized scattering equations and corresponding inelastic-cross-section expressions for comprehensive electron diffraction conditions

    NASA Astrophysics Data System (ADS)

    Allen, L. J.; Josefsson, T. W.

    1996-05-01

    Generalized scattering equations for electron diffraction in a crystalline environment have recently been derived with the assumption that the zeroth-order Laue zone (ZOLZ) lies parallel to the crystal surface (or alternatively that the zone axis is parallel to the crystal surface normal) [L. J. Allen and T. W. Josefsson, Phys. Rev. B 52, 3184 (1995)]. The contribution from higher-order Laue zones (HOLZ's) was not considered. We show that these scattering equations are in fact valid for general orientations of the ZOLZ with respect to the crystal surface, except for the specific case where the ZOLZ lies perpendicular to the surface. Furthermore, a widely applicable expression for the cross section for any type of inelastic scattering in a crystal is shown to be valid for any orientation of the ZOLZ and allows the inclusion of reflections in the HOLZ's.

  19. 22 CFR 211.3 - Cooperating sponsor agreements; program procedure.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the terms and conditions set forth in Regulation 11. (b) Host Country Food for Peace Program Agreement... Agreement, enter into a separate written Host Country Food for Peace Agreement with the foreign government of each country for which title II commodities are transferred to the cooperating sponsor....

  20. 49 CFR 605.15 - Content of agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., DEPARTMENT OF TRANSPORTATION SCHOOL BUS OPERATIONS School Bus Agreements § 605.15 Content of agreement. (a... bus operations shall, as a condition of assistance, enter into a written agreement required by § 605... equipment agrees that it will not engage in school bus operations in competition with private school...

  1. 48 CFR 31.109 - Advance agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... sampling methodologies at 31.201-6(c). However, an advance agreement is not an absolute requirement and the...) Precontract costs; (5) Independent research and development and bid and proposal costs; (6) Royalties and...) Professional services (e.g., legal, accounting, and engineering); (13) General and administrative costs...

  2. 24 CFR 200.1525 - Settlement agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... URBAN DEVELOPMENT GENERAL INTRODUCTION TO FHA PROGRAMS Multifamily Accelerated Processing (MAP): MAP... negotiate a settlement agreement with a MAP lender before or after the issuance of a warning letter or referral to the MAP Lender Review Board. Once a matter has been referred to the MAP Lender Review...

  3. 45 CFR 96.132 - Additional agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... and treatment of substance abuse, the requirement involved is unnecessary for maintaining quality in... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION BLOCK GRANTS Substance Abuse Prevention and Treatment Block Grant § 96.132 Additional agreements. (a) With respect...

  4. 45 CFR 96.132 - Additional agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... and treatment of substance abuse, the requirement involved is unnecessary for maintaining quality in... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION BLOCK GRANTS Substance Abuse Prevention and Treatment Block Grant § 96.132 Additional agreements. (a) With respect...

  5. 45 CFR 96.132 - Additional agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... and treatment of substance abuse, the requirement involved is unnecessary for maintaining quality in... Public Welfare Department of Health and Human Services GENERAL ADMINISTRATION BLOCK GRANTS Substance Abuse Prevention and Treatment Block Grant § 96.132 Additional agreements. (a) With respect...

  6. 45 CFR 96.132 - Additional agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... and treatment of substance abuse, the requirement involved is unnecessary for maintaining quality in... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION BLOCK GRANTS Substance Abuse Prevention and Treatment Block Grant § 96.132 Additional agreements. (a) With respect...

  7. 45 CFR 96.132 - Additional agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... and treatment of substance abuse, the requirement involved is unnecessary for maintaining quality in... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION BLOCK GRANTS Substance Abuse Prevention and Treatment Block Grant § 96.132 Additional agreements. (a) With respect...

  8. Assessment of pharmacogenomic agreement.

    PubMed

    Safikhani, Zhaleh; El-Hachem, Nehme; Quevedo, Rene; Smirnov, Petr; Goldenberg, Anna; Juul Birkbak, Nicolai; Mason, Christopher; Hatzis, Christos; Shi, Leming; Aerts, Hugo Jwl; Quackenbush, John; Haibe-Kains, Benjamin

    2016-01-01

    In 2013 we published an analysis demonstrating that drug response data and gene-drug associations reported in two independent large-scale pharmacogenomic screens, Genomics of Drug Sensitivity in Cancer (GDSC) and Cancer Cell Line Encyclopedia (CCLE), were inconsistent. The GDSC and CCLE investigators recently reported that their respective studies exhibit reasonable agreement and yield similar molecular predictors of drug response, seemingly contradicting our previous findings. Reanalyzing the authors' published methods and results, we found that their analysis failed to account for variability in the genomic data and more importantly compared different drug sensitivity measures from each study, which substantially deviate from our more stringent consistency assessment. Our comparison of the most updated genomic and pharmacological data from the GDSC and CCLE confirms our published findings that the measures of drug response reported by these two groups are not consistent. We believe that a principled approach to assess the reproducibility of drug sensitivity predictors is necessary before envisioning their translation into clinical settings. PMID:27408686

  9. Assessment of pharmacogenomic agreement

    PubMed Central

    Safikhani, Zhaleh; El-Hachem, Nehme; Quevedo, Rene; Smirnov, Petr; Goldenberg, Anna; Juul Birkbak, Nicolai; Mason, Christopher; Hatzis, Christos; Shi, Leming; Aerts, Hugo JWL; Quackenbush, John; Haibe-Kains, Benjamin

    2016-01-01

    In 2013 we published an analysis demonstrating that drug response data and gene-drug associations reported in two independent large-scale pharmacogenomic screens, Genomics of Drug Sensitivity in Cancer (GDSC) and Cancer Cell Line Encyclopedia (CCLE), were inconsistent. The GDSC and CCLE investigators recently reported that their respective studies exhibit reasonable agreement and yield similar molecular predictors of drug response, seemingly contradicting our previous findings. Reanalyzing the authors’ published methods and results, we found that their analysis failed to account for variability in the genomic data and more importantly compared different drug sensitivity measures from each study, which substantially deviate from our more stringent consistency assessment. Our comparison of the most updated genomic and pharmacological data from the GDSC and CCLE confirms our published findings that the measures of drug response reported by these two groups are not consistent. We believe that a principled approach to assess the reproducibility of drug sensitivity predictors is necessary before envisioning their translation into clinical settings. PMID:27408686

  10. Agreement with Subjects in Lubukusu

    ERIC Educational Resources Information Center

    Diercks, Michael J. K.

    2010-01-01

    This dissertation examines three topics in the morphosyntax of Lubukusu (Bantu, Kenya), all of which are concerned with agreement with subjects: locative inversion, complementizer agreement, and alternative agreement effects in subject extraction. Each topic reports novel Lubukusu data which are both typologically interesting and theoretically…

  11. A semi analytical method for electro-thermo-mechanical nonlinear vibration analysis of nanobeam resting on the Winkler-Pasternak foundations with general elastic boundary conditions

    NASA Astrophysics Data System (ADS)

    Zarepour, Misagh; Amirhosein Hosseini, Seyed

    2016-08-01

    This study presents an examination of nonlinear free vibration of a nanobeam under electro-thermo-mechanical loading with elastic medium and various boundary conditions, especially the elastic boundary condition. The nanobeam is modeled as an Euler–Bernoulli beam. The von Kármán strain-displacement relationship together with Hamilton’s principle and Eringen’s theory are employed to derive equations of motion. The nonlinear free vibration frequency is obtained for simply supported (S-S) and elastic supported (E-E) boundary conditions. E-E boundary condition is a general and actual form of boundary conditions and it is chosen because of more realistic behavior. By applying the differential transform method (DTM), the nanobeam’s natural frequencies can be easily obtained for the two different boundary conditions mentioned above. Performing a precise study led to investigation of the influences of nonlocal parameter, temperature change, spring constants (either for elastic medium or boundary condition) and imposed electric potential on the nonlinear free vibration characteristics of nanobeam. The results for S-S and E-E nanobeams are compared with each other. In order to validate the results, some comparisons are presented between DTM results and open literature to show the accuracy of this new approach. It has been discovered that DTM solves the equations with minimum calculation cost.

  12. A semi analytical method for electro-thermo-mechanical nonlinear vibration analysis of nanobeam resting on the Winkler-Pasternak foundations with general elastic boundary conditions

    NASA Astrophysics Data System (ADS)

    Zarepour, Misagh; Amirhosein Hosseini, Seyed

    2016-08-01

    This study presents an examination of nonlinear free vibration of a nanobeam under electro-thermo-mechanical loading with elastic medium and various boundary conditions, especially the elastic boundary condition. The nanobeam is modeled as an Euler-Bernoulli beam. The von Kármán strain-displacement relationship together with Hamilton’s principle and Eringen’s theory are employed to derive equations of motion. The nonlinear free vibration frequency is obtained for simply supported (S-S) and elastic supported (E-E) boundary conditions. E-E boundary condition is a general and actual form of boundary conditions and it is chosen because of more realistic behavior. By applying the differential transform method (DTM), the nanobeam’s natural frequencies can be easily obtained for the two different boundary conditions mentioned above. Performing a precise study led to investigation of the influences of nonlocal parameter, temperature change, spring constants (either for elastic medium or boundary condition) and imposed electric potential on the nonlinear free vibration characteristics of nanobeam. The results for S-S and E-E nanobeams are compared with each other. In order to validate the results, some comparisons are presented between DTM results and open literature to show the accuracy of this new approach. It has been discovered that DTM solves the equations with minimum calculation cost.

  13. Using General-Head Boundary Condition in Groundwater Flow Model Eddy Teasdale, PG; Jim Zhang, PhD, PE; and Liz Elliot, PG

    NASA Astrophysics Data System (ADS)

    Teasdale, E.

    2010-12-01

    : In groundwater flow model development, setting appropriate boundary conditions is difficult if the edges of the model domain are not natural groundwater or known hydraulic boundaries (i.e., rivers, faults). Often the prescribed-head or prescribed-flux boundary condition does not apply to these non-natural boundaries, and a general-head boundary (GHB) condition has to be implemented. GHB allows groundwater to move either into or out of the model domain (depending on groundwater elevation changes along the boundary). GHB conditions can approximate the hydraulic response of the boundaries to the groundwater condition variations if it is specified appropriately. Although hydraulic conductance and the reference head are the only two parameters used in GHB, determing these two parameters is always a challenging task, especially if little is known about the regional flow system. This paper presents the main issues in the application of GHB conditions and provides some guidance in determing the hydraulic conductance and the reference head values. Numerical test runs have been conducted to illustrate the effects varying GHB conditions have on the flow simulation results.

  14. Histidine-functionalized water-soluble nanoparticles for biomimetic nucleophilic/general-base catalysis under acidic conditions.

    PubMed

    Chadha, Geetika; Zhao, Yan

    2013-10-21

    Cross-linking the micelles of 4-dodecyloxybenzyltripropargylammonium bromide by 1,4-diazidobutane-2,3-diol in the presence of azide-functionalized imidazole derivatives yielded surface-cross-linked micelles (SCMs) with imidazole groups on the surface. The resulting water-soluble nanoparticles were found, by fluorescence spectroscopy, to contain hydrophobic binding sites. The imidazole groups promoted the photo-deprotonation of 2-naphthol at pH 6 and catalyzed the hydrolysis of p-nitrophenylacetate (PNPA) in aqueous solution at pH ≥ 4. Although the overall hydrolysis rate slowed down with decreasing solution pH, the catalytic effect of the imidazole became stronger because the reactions catalyzed by unfunctionalized SCMs slowed down much more. The unusual ability of the imidazole–SCMs to catalyze the hydrolysis of PNPA under acidic conditions was attributed to the local hydrophobicity and the positive nature of the SCMs.

  15. STUDIES IN RESUSCITATION: I. THE GENERAL CONDITIONS AFFECTING RESUSCITATION, AND THE RESUSCITATION OF THE BLOOD AND OF THE HEART

    PubMed Central

    Pike, F. H.; Guthrie, C. C.; Stewart, G. N.

    1908-01-01

    Our results may be briefly summarized: 1. Blood, when defibrinated, soon loses its power to maintain the activity of the higher nervous centers, and its nutritive properties for all tissues quickly diminish. 2. Artificial fluids, as a substitute for blood, are not satisfactory. 3. The proper oxygenation of the blood is an indispensable adjunct in the resuscitation of an animal. 4. The heart usually continues to beat for some minutes after it ceases to affect a mercury manometer, and resuscitation of it within this period by extra-thoracic massage and artificial respiration is sometimes successful. 5. Resuscitation of the heart by direct massage is the most certain method at our command. 6. A proper blood-pressure is an indispensable condition for the continued normal activity of the heart. 7. Anæsthetics, hemorrhage and induced currents applied to the heart render resuscitation more difficult than asphyxia alone. PMID:19867138

  16. Reducing indoor air pollution by air conditioning is associated with improvements in cardiovascular health among the general population.

    PubMed

    Lin, Lian-Yu; Chuang, Hsiao-Chi; Liu, I-Jung; Chen, Hua-Wei; Chuang, Kai-Jen

    2013-10-01

    Indoor air pollution is associated with cardiovascular effects, however, little is known about the effects of improving indoor air quality on cardiovascular health. The aim of this study was to explore whether improving indoor air quality through air conditioning can improve cardiovascular health in human subjects. We recruited a panel of 300 healthy subjects from Taipei, aged 20 and over, to participate in six home visits each, to measure a variety of cardiovascular endpoints, including high sensitivity-C-reactive protein (hs-CRP), 8-hydroxy-2'-deoxyguanosine (8-OHdG), fibrinogen in plasma and heart rate variability (HRV). Indoor particles and total volatile organic compounds (VOCs) were measured simultaneously at the participant's home during each visit. Three exposure conditions were investigated in this study: participants were requested to keep their windows open during the first two visits, close their windows during the next two visits, and close the windows and turn on their air conditioners during the last two visits. We used linear mixed-effects models to associate the cardiovascular endpoints with individual indoor air pollutants. The results showed that increases in hs-CRP, 8-OHdG and fibrinogen, and decreases in HRV indices were associated with increased levels of indoor particles and total VOCs in single-pollutant and two-pollutant models. The effects of indoor particles and total VOCs on cardiovascular endpoints were greatest during visits with the windows open. During visits with the air conditioners turned on, no significant changes in cardiovascular endpoints were observed. In conclusion, indoor air pollution is associated with inflammation, oxidative stress, blood coagulation and autonomic dysfunction. Reductions in indoor air pollution and subsequent improvements in cardiovascular health can be achieved by closing windows and turning on air conditioners at home.

  17. SFTG international collaborative study on in vitro micronucleus test I. General conditions and overall conclusions of the study.

    PubMed

    Lorge, Elisabeth; Thybaud, Veronique; Aardema, Marilyn J; Oliver, Jo; Wakata, Akihiro; Lorenzon, Giocondo; Marzin, Daniel

    2006-08-01

    This study, coordinated by the SFTG (French branch of European Environmental Mutagen Society), included 38 participants from Europe, Japan and America. Clastogens (bleomycin, urethane), including base and nucleoside analogs (5-fluorouracil and cytosine arabinoside), aneugens and/or polyploidy inducers (colchicine, diethylstilboestrol, griseofulvin and thiabendazole), as well as non-genotoxic compounds (mannitol and clofibrate), were tested. Four cell types were used, i.e. human lymphocytes in the presence of cytochalasin B and CHO, CHL and L5178Y cell lines, in the presence or absence of cytochalasin B, with various treatment-recovery schedules. Mitomycin C was used as a positive control for all cell types. Mannitol and clofibrate were consistently negative in all cell types and with all treatment-recovery conditions. Urethane, known to induce questionable clastogenicity, was not found as positive. Bleomycin and mitomycin C were found positive in all treatment-recovery conditions. The base and nucleoside analogs were less easy to detect, especially 5-fluorouracil due to the interference with cytotoxicity, while cytosine arabinoside was detected in all cell types depending on the treatment-recovery schedule. Aneugens (colchicine, diethylstilboestrol and griseofulvin) were all detected in all cell types. In this study, the optimal detection was ensured when a short treatment followed by a long recovery was associated with a long continuous treatment without recovery. There was no impact of the presence or absence of cytochalasin B on the detection of micronucleated cells on cell lines. Scoring micronucleated cells in both mononucleated and binucleated cells when using cytochalasin B was confirmed to be useful for the detection and the identification of aneugens. In conclusion, these results, together with previously published validation studies, provide a useful contribution to the optimisation of a study protocol for the detection of both clastogens and aneugens in

  18. 19 CFR 10.560 - General.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false General. 10.560 Section 10.560 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. United States-Singapore Free Trade Agreement Penalties §...

  19. 19 CFR 10.560 - General.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false General. 10.560 Section 10.560 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. United States-Singapore Free Trade Agreement Penalties §...

  20. 19 CFR 10.560 - General.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false General. 10.560 Section 10.560 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. United States-Singapore Free Trade Agreement Penalties §...

  1. 19 CFR 10.560 - General.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false General. 10.560 Section 10.560 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. United States-Singapore Free Trade Agreement Penalties §...

  2. 19 CFR 10.560 - General.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false General. 10.560 Section 10.560 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. United States-Singapore Free Trade Agreement Penalties §...

  3. 19 CFR 10.480 - General.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false General. 10.480 Section 10.480 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. United States-Chile Free Trade Agreement Penalties §...

  4. 19 CFR 10.930 - General.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false General. 10.930 Section 10.930 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. United States-Peru Trade Promotion Agreement Penalties §...

  5. 19 CFR 10.930 - General.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false General. 10.930 Section 10.930 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. United States-Peru Trade Promotion Agreement Penalties §...

  6. 19 CFR 10.930 - General.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false General. 10.930 Section 10.930 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. United States-Peru Trade Promotion Agreement Penalties §...

  7. 14 CFR 431.75 - Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... TRANSPORTATION LICENSING LAUNCH AND REENTRY OF A REUSABLE LAUNCH VEHICLE (RLV) Post-Licensing Requirements-Reusable Launch Vehicle Mission License Terms and Conditions § 431.75 Agreements. (a) Launch and reentry... launch range or licensed launch or reentry site operator, a licensee or applicant shall enter into...

  8. 14 CFR 431.75 - Agreements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... TRANSPORTATION LICENSING LAUNCH AND REENTRY OF A REUSABLE LAUNCH VEHICLE (RLV) Post-Licensing Requirements-Reusable Launch Vehicle Mission License Terms and Conditions § 431.75 Agreements. (a) Launch and reentry... launch range or licensed launch or reentry site operator, a licensee or applicant shall enter into...

  9. 14 CFR 431.75 - Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... TRANSPORTATION LICENSING LAUNCH AND REENTRY OF A REUSABLE LAUNCH VEHICLE (RLV) Post-Licensing Requirements-Reusable Launch Vehicle Mission License Terms and Conditions § 431.75 Agreements. (a) Launch and reentry... launch range or licensed launch or reentry site operator, a licensee or applicant shall enter into...

  10. 14 CFR 431.75 - Agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... TRANSPORTATION LICENSING LAUNCH AND REENTRY OF A REUSABLE LAUNCH VEHICLE (RLV) Post-Licensing Requirements-Reusable Launch Vehicle Mission License Terms and Conditions § 431.75 Agreements. (a) Launch and reentry... launch range or licensed launch or reentry site operator, a licensee or applicant shall enter into...

  11. A master-slave parallel hybrid multi-objective evolutionary algorithm for groundwater remediation design under general hydrogeological conditions

    NASA Astrophysics Data System (ADS)

    Wu, J.; Yang, Y.; Luo, Q.; Wu, J.

    2012-12-01

    This study presents a new hybrid multi-objective evolutionary algorithm, the niched Pareto tabu search combined with a genetic algorithm (NPTSGA), whereby the global search ability of niched Pareto tabu search (NPTS) is improved by the diversification of candidate solutions arose from the evolving nondominated sorting genetic algorithm II (NSGA-II) population. Also, the NPTSGA coupled with the commonly used groundwater flow and transport codes, MODFLOW and MT3DMS, is developed for multi-objective optimal design of groundwater remediation systems. The proposed methodology is then applied to a large-scale field groundwater remediation system for cleanup of large trichloroethylene (TCE) plume at the Massachusetts Military Reservation (MMR) in Cape Cod, Massachusetts. Furthermore, a master-slave (MS) parallelization scheme based on the Message Passing Interface (MPI) is incorporated into the NPTSGA to implement objective function evaluations in distributed processor environment, which can greatly improve the efficiency of the NPTSGA in finding Pareto-optimal solutions to the real-world application. This study shows that the MS parallel NPTSGA in comparison with the original NPTS and NSGA-II can balance the tradeoff between diversity and optimality of solutions during the search process and is an efficient and effective tool for optimizing the multi-objective design of groundwater remediation systems under complicated hydrogeologic conditions.

  12. Perceptions of patient provider agreements

    PubMed Central

    Albrecht, Jennifer S.; Khokhar, Bilal; Pradel, Françoise; Campbell, Michelle; Palmer, Jacqueline; Harris, Ilene; Palumbo, Francis

    2016-01-01

    Objectives Use of patient provider agreements (PPAs) is increasing, yet there is limited evidence on the effectiveness of PPAs to prevent prescription opioid misuse and diversion, and few guidelines for providers. We conducted eight focus groups to understand patient and prescriber perceptions of PPAs. Methods We recruited 40 patients who had been asked to sign a PPA and 40 prescribers who had administered at least one PPA. We developed topic guides for the two groups based on prior literature. Focus groups were audio-recorded and transcribed verbatim. Two investigators independently performed the content analysis of the transcripts and reached consensus on recurring themes. Key findings PPA use varied according to physician specialty. General practitioners used PPAs the least but reported increasing pressure from liability insurers to use them. Many patients reported signing a PPA in the emergency room of a hospital. Prescribers and patients reported a lack of understanding among patients concerning the purpose and content of the PPA. Prescribers questioned the legal status of the PPA, while patients believed that the PPA was a legal document intended to protect prescribers. Patients and prescribers valued PPA content items differently, although both groups agreed that signing a PPA would not prevent opioid misuse. Conclusions We identified several themes concerning the administration, content, effectiveness and utility of PPAs that highlight areas of research to improve PPAs. We also describe trends requiring further investigation. Understanding content of importance to patients will facilitate the development of a patient-centred PPA. PMID:27293486

  13. Monitoring of Biomedical License Agreements

    PubMed Central

    Keller, George H.; Ferguson, Steven M.; Pan, Percy

    2009-01-01

    Because technology licensed from research organizations can play a significant role in drug innovation and the generation of novel biomedical products, licensee performance under such agreements must be effectively monitored. This is necessary so that resultant benefits, including public health improvement, may be returned to the innovator(s) as well as society at large. The tasks that comprise monitoring are varied, but all come under the general heading of ‘enforcement of license provisions’. Since 1996, the license monitoring and enforcement program established by the US National Institutes of Health (NIH) Group has collected about $US17 million in unpaid and underpaid license royalties through formal financial audits and other investigative activities. During the same period, the Office of Technology Transfer (OTT) settled more than 60 cases of suspected patent infringement, generating around 60 new licenses and collected both back and ongoing royalties. As these numbers show, an active and effective monitoring program is an essential part of any technology transfer or biomedical licensing program. PMID:19960074

  14. 75 FR 40837 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-14

    ....gov . Agreement No.: 011279-027. Title: Latin America Agreement. Parties: ABC Discussion Agreement; Caribbean Shipowners Association; Central America Discussion Agreement; Compania Libra de Navegacion Uruguay... America Discussion Agreement; and Zim Integrated Shipping Services, Ltd. Filing Party: Wayne R. Rohde,...

  15. Byzantine agreement method without authentication

    SciTech Connect

    Reischuk, R.K.

    1983-12-01

    This invention relates to a method for achieving Byzantine agreement without authentication among n 100 communicating processors using event counting and thresholding rather than message exchanges and evaluations.

  16. Experience and grammatical agreement: Statistical learning shapes number agreement production

    PubMed Central

    Haskell, Todd R.; Thornton, Robert; MacDonald, Maryellen C.

    2009-01-01

    A robust result in research on the production of grammatical agreement is that speakers are more likely to produce an erroneous verb with phrases such as the key to the cabinets, with a singular noun followed by a plural one, than with phrases such as the keys to the cabinet, where a plural noun is followed by a singular. These asymmetries are thought to reflect core language production processes. Previous accounts have attributed error patterns to a syntactic number feature present on plurals but not singulars. An alternative approach is presented in which a process similar to structural priming contributes to the error asymmetry via speakers' past experiences with related agreement constructions. A corpus analysis and two agreement production studies test this account. The results suggest that agreement production is shaped by statistical learning from past language experience. Implications for accounts of agreement are discussed. PMID:19942213

  17. Conditions for the cosmological viability of the most general scalar-tensor theories and their applications to extended Galileon dark energy models

    SciTech Connect

    Felice, Antonio De; Tsujikawa, Shinji E-mail: shinji@rs.kagu.tus.ac.jp

    2012-02-01

    In the Horndeski's most general scalar-tensor theories with second-order field equations, we derive the conditions for the avoidance of ghosts and Laplacian instabilities associated with scalar, tensor, and vector perturbations in the presence of two perfect fluids on the flat Friedmann-Lemaître-Robertson-Walker (FLRW) background. Our general results are useful for the construction of theoretically consistent models of dark energy. We apply our formulas to extended Galileon models in which a tracker solution with an equation of state smaller than -1 is present. We clarify the allowed parameter space in which the ghosts and Laplacian instabilities are absent and we numerically confirm that such models are indeed cosmologically viable.

  18. [Condition of patients after surgical wisdom tooth extraction under general anesthesia with different premedication variants--a prospective study based on a post-anesthesia questionnaire].

    PubMed

    Markus, H; Schwarz, A

    2001-01-01

    Evaluation of the modified "postanaesthesiological questionnaire" pointed to a subtle influencing of the condition of patients who had undergone 3rd molar surgery in general anaesthesia by using different premedication variants: "Atropine, Pethidine and Midazolam" (group A) and "Atropine, Midazolam and S-Ketamin" (group B). The combination in group B seems to be more suitable. On the one hand, a lower incidence of unwanted side-effects was found and, on the other hand, remarkable positive effects were observed. Of particular significance with this combination was also the more effective suppression of postoperative pain. The Propofol-supplemented general anaesthesia prepared in this way and administered using a nasal intubation technique found the full approval of the patients. Postoperative pain therapy was effective and also inexpensive, costing just 8.20 DM per patient, according to current prices calculated by Magdeburg University Hospital.

  19. [Condition of patients after surgical wisdom tooth extraction under general anesthesia with different premedication variants--a prospective study based on a post-anesthesia questionnaire].

    PubMed

    Markus, H; Schwarz, A

    2001-01-01

    Evaluation of the modified "postanaesthesiological questionnaire" pointed to a subtle influencing of the condition of patients who had undergone 3rd molar surgery in general anaesthesia by using different premedication variants: "Atropine, Pethidine and Midazolam" (group A) and "Atropine, Midazolam and S-Ketamin" (group B). The combination in group B seems to be more suitable. On the one hand, a lower incidence of unwanted side-effects was found and, on the other hand, remarkable positive effects were observed. Of particular significance with this combination was also the more effective suppression of postoperative pain. The Propofol-supplemented general anaesthesia prepared in this way and administered using a nasal intubation technique found the full approval of the patients. Postoperative pain therapy was effective and also inexpensive, costing just 8.20 DM per patient, according to current prices calculated by Magdeburg University Hospital. PMID:11799850

  20. Skills agreement. Recipe for success.

    PubMed

    Nolan, Alexis

    2007-06-21

    The aims of the national health Sector Skills Agreement need regional and local implementation by stakeholders to become reality. Work in the East of England will produce a first regional skills agreement later this year. The Harlow Project is producing award winning process on recuitment and retention. PMID:17847967

  1. Effects of parallel planning on agreement production.

    PubMed

    Veenstra, Alma; Meyer, Antje S; Acheson, Daniel J

    2015-11-01

    An important issue in current psycholinguistics is how the time course of utterance planning affects the generation of grammatical structures. The current study investigated the influence of parallel activation of the components of complex noun phrases on the generation of subject-verb agreement. Specifically, the lexical interference account (Gillespie & Pearlmutter, 2011b; Solomon & Pearlmutter, 2004) predicts more agreement errors (i.e., attraction) for subject phrases in which the head and local noun mismatch in number (e.g., the apple next to the pears) when nouns are planned in parallel than when they are planned in sequence. We used a speeded picture description task that yielded sentences such as the apple next to the pears is red. The objects mentioned in the noun phrase were either semantically related or unrelated. To induce agreement errors, pictures sometimes mismatched in number. In order to manipulate the likelihood of parallel processing of the objects and to test the hypothesized relationship between parallel processing and the rate of agreement errors, the pictures were either placed close together or far apart. Analyses of the participants' eye movements and speech onset latencies indicated slower processing of the first object and stronger interference from the related (compared to the unrelated) second object in the close than in the far condition. Analyses of the agreement errors yielded an attraction effect, with more errors in mismatching than in matching conditions. However, the magnitude of the attraction effect did not differ across the close and far conditions. Thus, spatial proximity encouraged parallel processing of the pictures, which led to interference of the associated conceptual and/or lexical representation, but, contrary to the prediction, it did not lead to more attraction errors. PMID:26454618

  2. Non-Markovian reduced propagator, multiple-time correlation functions, and master equations with general initial conditions in the weak-coupling limit

    SciTech Connect

    Vega, Ines de; Alonso, Daniel

    2006-02-15

    In this paper we derive the evolution equation for the reduced propagator, an object that evolves vectors of the Hilbert space of a system S interacting with an environment B in a non-Markovian way. This evolution is conditioned to certain initial and final states of the environment. Once an average over these environmental states is made, reduced propagators permit the evaluation of multiple-time correlation functions of system observables. When this average is done stochastically the reduced propagator evolves according to a stochastic Schroedinger equation. In addition, it is possible to obtain the evolution equations of the multiple-time correlation functions which generalize the well-known quantum regression theorem to the non-Markovian case. Here, both methods, stochastic and evolution equations, are described by assuming a weak coupling between system and environment. Finally, we show that reduced propagators can be used to obtain a master equation with general initial conditions, and not necessarily an initial vacuum state for the environment. We illustrate the theory with several examples.

  3. 20 CFR 404.1903 - Negotiating totalization agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Section 404.1903 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Totalization Agreements General Provisions § 404.1903 Negotiating totalization... entire country. However, agreements may only be negotiated with foreign countries that have a...

  4. 15 CFR 296.8 - Joint venture agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Joint venture agreement. 296.8 Section... PROGRAM General § 296.8 Joint venture agreement. NIST shall not issue a TIP award to a joint venture and no costs shall be incurred under a TIP project by the joint venture members until such time as...

  5. 15 CFR 296.8 - Joint venture agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Joint venture agreement. 296.8 Section... PROGRAM General § 296.8 Joint venture agreement. NIST shall not issue a TIP award to a joint venture and no costs shall be incurred under a TIP project by the joint venture members until such time as...

  6. 19 CFR 114.2 - Customs Conventions and Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Customs Conventions and Agreements. 114.2 Section 114.2 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CARNETS General Provisions § 114.2 Customs Conventions and Agreements....

  7. 49 CFR 604.4 - Charter service agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 7 2011-10-01 2011-10-01 false Charter service agreement. 604.4 Section 604.4 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL TRANSIT ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CHARTER SERVICE General provisions. § 604.4 Charter service agreement. (a) A recipient seeking Federal assistance...

  8. 46 CFR 390.6 - Administration of the agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Administration of the agreement. 390.6 Section 390.6 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS UNDER PUBLIC LAW 91-469 CAPITAL CONSTRUCTION FUND § 390.6 Administration of the agreement. (a) In general. The Maritime Administrator...

  9. 46 CFR 390.6 - Administration of the agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Administration of the agreement. 390.6 Section 390.6 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS UNDER PUBLIC LAW 91-469 CAPITAL CONSTRUCTION FUND § 390.6 Administration of the agreement. (a) In general. The Maritime Administrator...

  10. 32 CFR 505.13 - Computer Matching Agreement Program.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 3 2013-07-01 2013-07-01 false Computer Matching Agreement Program. 505.13... AUTHORITIES AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.13 Computer Matching Agreement Program. (a) General provisions. (1) Pursuant to the Privacy Act and this part, DA records may be subject to...

  11. 32 CFR 505.13 - Computer Matching Agreement Program.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 3 2014-07-01 2014-07-01 false Computer Matching Agreement Program. 505.13... AUTHORITIES AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.13 Computer Matching Agreement Program. (a) General provisions. (1) Pursuant to the Privacy Act and this part, DA records may be subject to...

  12. 32 CFR 505.13 - Computer Matching Agreement Program.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 3 2012-07-01 2009-07-01 true Computer Matching Agreement Program. 505.13... AUTHORITIES AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.13 Computer Matching Agreement Program. (a) General provisions. (1) Pursuant to the Privacy Act and this part, DA records may be subject to...

  13. 32 CFR 505.13 - Computer Matching Agreement Program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Computer Matching Agreement Program. 505.13... AUTHORITIES AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.13 Computer Matching Agreement Program. (a) General provisions. (1) Pursuant to the Privacy Act and this part, DA records may be subject to...

  14. 32 CFR 505.13 - Computer Matching Agreement Program.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 3 2011-07-01 2009-07-01 true Computer Matching Agreement Program. 505.13... AUTHORITIES AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.13 Computer Matching Agreement Program. (a) General provisions. (1) Pursuant to the Privacy Act and this part, DA records may be subject to...

  15. 48 CFR 227.676 - Foreign patent interchange agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Foreign patent interchange... SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Foreign License and Technical Assistance Agreements 227.676 Foreign patent interchange agreements. (a)...

  16. 48 CFR 227.676 - Foreign patent interchange agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Foreign patent interchange... SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Foreign License and Technical Assistance Agreements 227.676 Foreign patent interchange agreements. (a)...

  17. 48 CFR 227.676 - Foreign patent interchange agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Foreign patent interchange... SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Foreign License and Technical Assistance Agreements 227.676 Foreign patent interchange agreements. (a)...

  18. 48 CFR 227.676 - Foreign patent interchange agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Foreign patent interchange... SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Foreign License and Technical Assistance Agreements 227.676 Foreign patent interchange agreements. (a)...

  19. 48 CFR 227.676 - Foreign patent interchange agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Foreign patent interchange... SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Foreign License and Technical Assistance Agreements 227.676 Foreign patent interchange agreements. (a)...

  20. 20 CFR 322.5 - Payments under vacation agreements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false Payments under vacation agreements. 322.5 Section 322.5 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD UNEMPLOYMENT INSURANCE ACT REMUNERATION § 322.5 Payments under vacation agreements. (a) General. In ascertaining...

  1. 20 CFR 322.5 - Payments under vacation agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true Payments under vacation agreements. 322.5 Section 322.5 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD UNEMPLOYMENT INSURANCE ACT REMUNERATION § 322.5 Payments under vacation agreements. (a) General. In ascertaining...

  2. 20 CFR 322.5 - Payments under vacation agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Payments under vacation agreements. 322.5 Section 322.5 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD UNEMPLOYMENT INSURANCE ACT REMUNERATION § 322.5 Payments under vacation agreements. (a) General. In ascertaining...

  3. 20 CFR 322.5 - Payments under vacation agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false Payments under vacation agreements. 322.5 Section 322.5 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD UNEMPLOYMENT INSURANCE ACT REMUNERATION § 322.5 Payments under vacation agreements. (a) General. In ascertaining...

  4. 20 CFR 322.5 - Payments under vacation agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true Payments under vacation agreements. 322.5 Section 322.5 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD UNEMPLOYMENT INSURANCE ACT REMUNERATION § 322.5 Payments under vacation agreements. (a) General. In ascertaining...

  5. 18 CFR 35.10a - Forms of service agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Application § 35.10a Forms of service agreements. (a) To the extent a public utility adopts a standard form of service agreement for a service other than market-based power sales, the public utility shall include as... for each category of generally applicable service offered by the public utility under its...

  6. 18 CFR 35.10a - Forms of service agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Application § 35.10a Forms of service agreements. (a) To the extent a public utility adopts a standard form of service agreement for a service other than market-based power sales, the public utility shall include as... for each category of generally applicable service offered by the public utility under its...

  7. 18 CFR 35.10a - Forms of service agreements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Application § 35.10a Forms of service agreements. (a) To the extent a public utility adopts a standard form of service agreement for a service other than market-based power sales, the public utility shall include as... for each category of generally applicable service offered by the public utility under its...

  8. 18 CFR 35.10a - Forms of service agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Application § 35.10a Forms of service agreements. (a) To the extent a public utility adopts a standard form of service agreement for a service other than market-based power sales, the public utility shall include as... for each category of generally applicable service offered by the public utility under its...

  9. 41 CFR 60-250.62 - Conciliation agreements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Conciliation agreements. 60-250.62 Section 60-250.62 Public Contracts and Property Management Other Provisions Relating to... PROTECTED VETERANS General Enforcement and Complaint Procedures § 60-250.62 Conciliation agreements. If...

  10. 41 CFR 60-300.62 - Conciliation agreements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Conciliation agreements. 60-300.62 Section 60-300.62 Public Contracts and Property Management Other Provisions Relating to... MEDAL VETERANS General Enforcement and Complaint Procedures § 60-300.62 Conciliation agreements. If...

  11. 30 CFR 207.5 - Contract and sales agreement retention.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Contract and sales agreement retention. 207.5 Section 207.5 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT SALES AGREEMENTS OR CONTRACTS GOVERNING THE DISPOSAL OF LEASE PRODUCTS General Provisions §...

  12. Body Condition Scores and Evaluation of Feeding Habits of Dogs and Cats at a Low Cost Veterinary Clinic and a General Practice

    PubMed Central

    2016-01-01

    This study assessed body condition scores (BCS) and feeding habits for dogs and cats. Eighty-six cats and 229 dogs (and their owners) were enrolled from 2 clinics: a low cost clinic (n = 149) and a general practice (n = 166). BCS and body weight were recorded. Owners completed a survey which included animal age, sex, and breed; owner demographics; and feeding practices (e.g., diet, rationale for feeding practices). Owners from the low cost clinic had a significantly lower income (P < 0.001) and education (P < 0.001) compared to those from the general practice. Animals from the low cost clinic were younger (P < 0.001) and dogs were less likely to be neutered (P < 0.001). Overweight prevalence was 55% overall (P = 0.083), with a significantly higher prevalence in the general practice for cats (44% versus 66%; P = 0.046), but not for dogs (58% versus 53%; P = 0.230). Multivariate analysis showed that only neuter status was significantly associated with BCS (P = 0.004). Veterinarians were the most common source of nutritional information, though lack of accurate nutrition knowledge was common among all participants. These findings support the need for enhanced communication about optimal BCS and nutrition regardless of socioeconomic status. PMID:27722198

  13. The relative odds of lifetime health conditions and infectious diseases among men who have sex with men compared with a matched general population sample.

    PubMed

    Swartz, James A

    2015-03-01

    To address the understudy of health conditions and infectious diseases that are not strictly related to sexual transmission among men who have sex with men (MSM), this study examined the relative odds of 10 health conditions and two infectious diseases in a sample of MSM compared with a matched general population sample. MSM (N = 653) living mainly in Chicago were sampled through successive administrations of an Internet-based survey (2008-2010) that assessed physical and mental health, substance use, and HIV status. Propensity score matching was used to obtain a demographically comparable sample of men (N = 653) from aggregated administrations (2008-2012) of the National Survey on Drug Use and Health. Multivariate Firth logistic regressions compared the odds of ever having been diagnosed with each condition or disease, controlling for demographics, substance use, psychological distress, and HIV/AIDS status. MSM were more likely (p < .01) to have experienced: ulcers (odds ratio [OR] = 2.3), hypertension (OR = 2.1), liver disease (OR = 5.7), and sexually transmitted infections other than HIV/AIDS (OR = 8.9). Two other conditions, pneumonia and pancreatitis, as well as tuberculosis, were significant at p < .05 but below the statistical threshold used to reduce alpha error. The findings suggest that relative to non-sexual-minority men, MSM are more likely to experience a range of health conditions not specifically attributable to HIV/AIDS, sexual behavior, psychological distress, or substance use. The implications for research on the health status and provision of health care to MSM in light of the study findings are considered.

  14. 40 CFR 35.6220 - General.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Core Program Cooperative Agreements § 35.6220 General. The recipient of a Core Program Cooperative Agreement must...

  15. Federal Facility Agreement progress report

    SciTech Connect

    Not Available

    1993-10-01

    The (SRS) Federal Facility Agreement (FFA) was made effective by the US. Environmental Protection Agency Region IV (EPA) on August 16, 1993. To meet the reporting requirements in Section XXV of the Agreement, the FFA Progress Report was developed. The FFA Progress Report is the first of a series of quarterly progress reports to be prepared by the SRS. As such this report describes the information and action taken to September 30, 1993 on the SRS units identified for investigation and remediation in the Agreement. This includes; rubble pits, runoff basins, retention basin, seepage basin, burning pits, H-Area Tank 16, and spill areas.

  16. Suspension agreements: The status quota

    SciTech Connect

    1996-01-01

    Since the initial filing of anti-dumping actions uranium imports from the former Soviet Union, a maze of filings, agreements, amendments, bills, measures, and deals have emerged on which only the closest observers remain current. Even with all the actions that have taken place, none of the parties appear content with the status quo and changes to the agreements are ongoing. Given this dynamic state of affairs, a recap of events and a summary of the current agreements is helpful for understanding the concerns of the involved parties and digesting future events.

  17. 42 CFR 442.12 - Provider agreement: General requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... agency, if the facility fails to meet the civil rights requirements set forth in 45 CFR parts 80, 84, and... SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STANDARDS FOR PAYMENT TO NURSING FACILITIES AND... nursing facility services nor make Medicaid payments to a facility for those services unless the...

  18. 42 CFR 442.12 - Provider agreement: General requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... agency, if the facility fails to meet the civil rights requirements set forth in 45 CFR parts 80, 84, and... SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STANDARDS FOR PAYMENT TO NURSING FACILITIES AND... nursing facility services nor make Medicaid payments to a facility for those services unless the...

  19. Assessing agreement with multiple raters on correlated kappa statistics.

    PubMed

    Cao, Hongyuan; Sen, Pranab K; Peery, Anne F; Dellon, Evan S

    2016-07-01

    In clinical studies, it is often of interest to see the diagnostic agreement among clinicians on certain symptoms. Previous work has focused on the agreement between two clinicians under two different conditions or the agreement among multiple clinicians under one condition. Few have discussed the agreement study with a design where multiple clinicians examine the same group of patients under two different conditions. In this paper, we use the intraclass kappa statistic for assessing nominal scale agreement with such a design. We derive an explicit variance formula for the difference of correlated kappa statistics and conduct hypothesis testing for the equality of kappa statistics. Simulation studies show that the method performs well with realistic sample sizes and may be superior to a method that did not take into account the measurement dependence structure. The practical utility of the method is illustrated on data from an eosinophilic esophagitis (EoE) study.

  20. 77 FR 70527 - Request for Comments Concerning Compliance With Telecommunications Trade Agreements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-26

    ... States: The World Trade Organization (``WTO'') General Agreement on Trade in Services; The North American... practice of a country that has entered into a trade agreement or other telecommunications trade agreement...-agreements for links to U.S. FTAs); (5) Whether any country has failed to comply with its obligations...

  1. Good Agreements Make Good Friends

    PubMed Central

    Han, The Anh; Pereira, Luís Moniz; Santos, Francisco C.; Lenaerts, Tom

    2013-01-01

    When starting a new collaborative endeavor, it pays to establish upfront how strongly your partner commits to the common goal and what compensation can be expected in case the collaboration is violated. Diverse examples in biological and social contexts have demonstrated the pervasiveness of making prior agreements on posterior compensations, suggesting that this behavior could have been shaped by natural selection. Here, we analyze the evolutionary relevance of such a commitment strategy and relate it to the costly punishment strategy, where no prior agreements are made. We show that when the cost of arranging a commitment deal lies within certain limits, substantial levels of cooperation can be achieved. Moreover, these levels are higher than that achieved by simple costly punishment, especially when one insists on sharing the arrangement cost. Not only do we show that good agreements make good friends, agreements based on shared costs result in even better outcomes. PMID:24045873

  2. Quick Guide: Power Purchase Agreements

    SciTech Connect

    2010-06-25

    Introduction to Federal power purchase agreements (PPAs), including available FEMP services and technical assistance as well as questions to ask when evaluating PPAs for a Federal renewable energy project.

  3. Empirical agreement in model validation.

    PubMed

    Jebeile, Julie; Barberousse, Anouk

    2016-04-01

    Empirical agreement is often used as an important criterion when assessing the validity of scientific models. However, it is by no means a sufficient criterion as a model can be so adjusted as to fit available data even though it is based on hypotheses whose plausibility is known to be questionable. Our aim in this paper is to investigate into the uses of empirical agreement within the process of model validation.

  4. Application Agreement and Integration Services

    NASA Technical Reports Server (NTRS)

    Driscoll, Kevin R.; Hall, Brendan; Schweiker, Kevin

    2013-01-01

    Application agreement and integration services are required by distributed, fault-tolerant, safety critical systems to assure required performance. An analysis of distributed and hierarchical agreement strategies are developed against the backdrop of observed agreement failures in fielded systems. The documented work was performed under NASA Task Order NNL10AB32T, Validation And Verification of Safety-Critical Integrated Distributed Systems Area 2. This document is intended to satisfy the requirements for deliverable 5.2.11 under Task 4.2.2.3. This report discusses the challenges of maintaining application agreement and integration services. A literature search is presented that documents previous work in the area of replica determinism. Sources of non-deterministic behavior are identified and examples are presented where system level agreement failed to be achieved. We then explore how TTEthernet services can be extended to supply some interesting application agreement frameworks. This document assumes that the reader is familiar with the TTEthernet protocol. The reader is advised to read the TTEthernet protocol standard [1] before reading this document. This document does not re-iterate the content of the standard.

  5. Optimism about safety and group-serving interpretations of safety among pedestrians and cyclists in relation to road use in general and under low light conditions.

    PubMed

    King, M J; Wood, J M; Lacherez, P F; Marszalek, R P

    2012-01-01

    Drivers are known to be optimistic about their risk of crash involvement, believing that they are less likely to be involved in a crash than other drivers. However, little comparative research has been conducted among other road users. In addition, optimism about crash risk is conceptualised as applying only to an individual's assessment of his or her personal risk of crash involvement. The possibility that the self-serving nature of optimism about safety might be generalised to the group-level as a cyclist or a pedestrian, i.e., becoming group-serving rather than self-serving, has been overlooked in relation to road safety. This study analysed a subset of data collected as part of a larger research project on the visibility of pedestrians, cyclists and road workers, focusing on a set of questionnaire items administered to 406 pedestrians, 838 cyclists and 622 drivers. The items related to safety in various scenarios involving drivers, pedestrians and cyclists, allowing predictions to be derived about group differences in agreement with items based on the assumption that the results would exhibit group-serving bias. Analysis of the responses indicated that specific hypotheses about group-serving interpretations of safety and responsibility were supported in 22 of the 26 comparisons. When the nine comparisons relevant to low lighting conditions were considered separately, seven were found to be supported. The findings of the research have implications for public education and for the likely acceptance of messages which are inconsistent with current assumptions and expectations of pedestrians and cyclists. They also suggest that research into group-serving interpretations of safety, even for temporary roles rather than enduring groups, could be fruitful. Further, there is an implication that gains in safety can be made by better educating road users about the limitations of their visibility and the ramifications of this for their own road safety, particularly in low

  6. 7 CFR 247.4 - Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.4 Agreements. (a) What agreements are..., sex, or disability. (d) What is the duration of required agreements? Agreements between FNS and...

  7. 7 CFR 247.4 - Agreements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.4 Agreements. (a) What agreements are..., sex, or disability. (d) What is the duration of required agreements? Agreements between FNS and...

  8. 12 CFR 1805.802 - Assistance Agreement; sanctions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Assistance Agreement; sanctions. 1805.802 Section 1805.802 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS PROGRAM Terms and Conditions of Assistance § 1805.802 Assistance Agreement; sanctions. (a)...

  9. From surface to volume plasmons in hyperbolic metamaterials: General existence conditions for bulk high-k waves in metal-dielectric and graphene-dielectric multilayers

    NASA Astrophysics Data System (ADS)

    Zhukovsky, Sergei V.; Andryieuski, Andrei; Sipe, J. E.; Lavrinenko, Andrei V.

    2014-10-01

    We theoretically investigate general existence conditions for broadband bulk large-wave-vector (high-k) propagating waves (such as volume plasmon polaritons in hyperbolic metamaterials) in subwavelength periodic multilayer structures. Describing the elementary excitation in the unit cell of the structure by a generalized resonance pole of a reflection coefficient and using Bloch's theorem, we derive analytical expressions for the band of large-wave-vector propagating solutions. We apply our formalism to determine the high-k band existence in two important cases: the well-known metal-dielectric and recently introduced graphene-dielectric stacks. We confirm that short-range surface plasmons in thin metal layers can give rise to hyperbolic metamaterial properties and demonstrate that long-range surface plasmons cannot. We also show that graphene-dielectric multilayers tend to support high-k waves and explore the range of parameteres for which this is possible, confirming the prospects of using graphene for materials with hyperbolic dispersion. The approach is applicable to a large variety of structures, such as continuous or structured microwave, terahertz, and optical metamaterials.

  10. Two decades of change in European general practice service profiles: conditions associated with the developments in 28 countries between 1993 and 2012

    PubMed Central

    Schäfer, Willemijn L. A.; Boerma, Wienke G. W.; Spreeuwenberg, Peter; Schellevis, François G.; Groenewegen, Peter P.

    2016-01-01

    Objective Evidence regarding the benefits of strong primary care has influenced health policy and practice. This study focuses on changes in the breadth of services provided by general practitioners (GPs) in Europe between 1993 and 2012 and offers possible explanations for these changes. Design Data on the breadth of service profiles were used from two cross-sectional surveys in 28 countries: the 1993 European GP Task Profile study (6321 GPs) and the 2012 QUALICOPC study (6044 GPs). GPs’ involvement in four areas of clinical activity (first contact care, treatment of diseases, medical procedures, and prevention) was established using ecometric analyses. The changes were measured by the relative increase in the breadth of service profiles. Associations between changes and national-level conditions were examined though regression analyses. Data on the national conditions were used from various other public databases including the World Databank and the PHAMEU (Primary Health care Activity Monitor) database. Setting A total of 28 European countries. Subjects GPs. Main outcome measure Changes in the breadth of GP service profiles. Results A general trend of increased involvement of European GPs in treatment of diseases and decreased involvement in preventive activities was observed. Conditions at the national level were associated with changes in the involvement of GPs in first contact care, treatment of diseases and, to a limited extent, prevention. Especially in countries with stronger growth of health care expenditures between 1993 and 2012 the service profiles have expanded. In countries where family values are more dominant the breadth in service profiles decreased. A stronger professional status of GPs was positively associated with the change in first contact care. Conclusions GPs in former communist countries and Turkey have increased their involvement in the provision of services. Developments in Western Europe were less evident. The developments in the

  11. 44 CFR 206.44 - FEMA-State Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Households Program. (b) Terms and conditions. This Agreement describes the incident and the incident period... close or amend the incident period, to add forms of assistance not originally authorized, or...

  12. Gender agreement and multiple referents.

    PubMed

    Finocchiaro, Chiara; Mahon, Bradford Z; Caramazza, Alfonso

    2008-01-01

    We report a new pattern of usage in current, spoken Italian that has implications for both psycholinguistic models of language production and linguistic theories of language change. In Italian, gender agreement is mandatory for both singular and plural nouns. However, when two or more nouns of different grammatical gender appear in a conjoined noun phrase (NP), masculine plural agreement is required. In this study, we combined on-line and off-line methodologies in order to assess the mechanisms involved in gender marking in the context of multiple referents. The results of two pronoun production tasks showed that plural feminine agreement was significantly more difficult than plural masculine agreement. In a separate study using offline judgements of acceptability, we found that agreement violations in Italian are tolerated more readily in the case of feminine conjoined noun phrases (e.g., la mela e la banana 'the:fem apple:fem and the: fem banana: fem') than masculine conjoined noun phrases (e.g., il fiore e il libro 'the:mas flower: mas and the:mas book:mas'). Implications of these results are discussed both at the level of functional architecture within the language production system and at the level of changes in language use. PMID:21037930

  13. Gender agreement and multiple referents.

    PubMed

    Finocchiaro, Chiara; Mahon, Bradford Z; Caramazza, Alfonso

    2008-01-01

    We report a new pattern of usage in current, spoken Italian that has implications for both psycholinguistic models of language production and linguistic theories of language change. In Italian, gender agreement is mandatory for both singular and plural nouns. However, when two or more nouns of different grammatical gender appear in a conjoined noun phrase (NP), masculine plural agreement is required. In this study, we combined on-line and off-line methodologies in order to assess the mechanisms involved in gender marking in the context of multiple referents. The results of two pronoun production tasks showed that plural feminine agreement was significantly more difficult than plural masculine agreement. In a separate study using offline judgements of acceptability, we found that agreement violations in Italian are tolerated more readily in the case of feminine conjoined noun phrases (e.g., la mela e la banana 'the:fem apple:fem and the: fem banana: fem') than masculine conjoined noun phrases (e.g., il fiore e il libro 'the:mas flower: mas and the:mas book:mas'). Implications of these results are discussed both at the level of functional architecture within the language production system and at the level of changes in language use.

  14. Gender agreement and multiple referents

    PubMed Central

    Finocchiaro, Chiara; Mahon, Bradford Z.; Caramazza, Alfonso

    2010-01-01

    We report a new pattern of usage in current, spoken Italian that has implications for both psycholinguistic models of language production and linguistic theories of language change. In Italian, gender agreement is mandatory for both singular and plural nouns. However, when two or more nouns of different grammatical gender appear in a conjoined noun phrase (NP), masculine plural agreement is required. In this study, we combined on-line and off-line methodologies in order to assess the mechanisms involved in gender marking in the context of multiple referents. The results of two pronoun production tasks showed that plural feminine agreement was significantly more difficult than plural masculine agreement. In a separate study using offline judgements of acceptability, we found that agreement violations in Italian are tolerated more readily in the case of feminine conjoined noun phrases (e.g., la mela e la banana ‘the:fem apple:fem and the: fem banana: fem’) than masculine conjoined noun phrases (e.g., il fiore e il libro ‘the:mas flower: mas and the:mas book:mas’). Implications of these results are discussed both at the level of functional architecture within the language production system and at the level of changes in language use.* PMID:21037930

  15. Experience and Grammatical Agreement: Statistical Learning Shapes Number Agreement Production

    ERIC Educational Resources Information Center

    Haskell, Todd R.; Thornton, Robert; MacDonald, Maryellen C.

    2010-01-01

    A robust result in research on the production of grammatical agreement is that speakers are more likely to produce an erroneous verb with phrases such as "the key to the cabinets", with a singular noun followed by a plural one, than with phrases such as "the keys to the cabinet", where a plural noun is followed by a singular. These asymmetries are…

  16. Authenticated algorithms for Byzantine agreement

    SciTech Connect

    Dolev, D.; Strong, H.R.

    1983-11-01

    Reaching agreement in a distributed system in the presence of fault processors is a central issue for reliable computer systems. Using an authentication protocol, one can limit the undetected behavior of faulty processors to a simple failure to relay messages to all intended targets. In this paper the authors show that, in spite of such an ability to limit faulty behavior, and no matter what message types or protocols are allowed, reaching (Byzantine) agreement requires at least t+1 phases or rounds of information exchange, where t is an upper bound on the number of faulty processors. They present algorithms for reaching agreement based on authentication that require a total number of messages sent by correctly operating processors that is polynomial in both t and the number of processors, n. The best algorithm uses only t+1 phases and o(nt) messages. 9 references.

  17. 76 FR 20372 - Notice of Lodging of Consent Decree and Settlement Agreement Regarding Natural Resource Damage...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-12

    ... of Lodging of Consent Decree and Settlement Agreement Regarding Natural Resource Damage Claims... St. Regis Mohawk Tribe. The NRD Settlement Agreement resolves claims for natural resource damages and... be addressed to the Assistant Attorney General, Environment and Natural Resources Division,...

  18. 42 CFR 485.616 - Condition of participation: Agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... State law, which categories of practitioners are eligible candidates for appointment to the medical... such information for use in the periodic appraisal of the individual distant-site physician or...-site telemedicine entity such information for use in the periodic appraisal of the...

  19. 14 CFR 1260.51 - Cooperative agreement special condition.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Recipient mutually agree to the following statement of anticipated cooperative interactions which may occur... description of the work and insert a concise statement of the exact nature of the cooperative...

  20. 42 CFR 485.616 - Condition of participation: Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Section 485.616 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... development and use of communications systems of the network, including the network's system for the... system; and (3) The provision of emergency and nonemergency transportation between the facility and...