Science.gov

Sample records for agreement required development

  1. 22 CFR 124.7 - Information required in all manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Information required in all manufacturing license agreements and technical assistance agreements. 124.7 Section 124.7 Foreign Relations DEPARTMENT... DEFENSE SERVICES § 124.7 Information required in all manufacturing license agreements and...

  2. 42 CFR 460.30 - Program agreement requirement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PACE Program Agreement § 460.30 Program agreement requirement. (a) A PACE organization...

  3. 42 CFR 460.30 - Program agreement requirement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PACE Program Agreement § 460.30 Program agreement requirement. (a) A PACE organization...

  4. 42 CFR 460.30 - Program agreement requirement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PACE Program Agreement § 460.30 Program agreement requirement. (a) A PACE organization...

  5. 42 CFR 460.30 - Program agreement requirement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PACE Program Agreement § 460.30 Program agreement requirement. (a) A PACE organization...

  6. 42 CFR 460.30 - Program agreement requirement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PACE Program Agreement § 460.30 Program agreement requirement. (a) A PACE organization...

  7. 22 CFR 124.8 - Clauses required both in manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Clauses required both in manufacturing license agreements and technical assistance agreements. 124.8 Section 124.8 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS AGREEMENTS, OFF-SHORE PROCUREMENT AND OTHER DEFENSE SERVICES §...

  8. 42 CFR 442.12 - Provider agreement: General requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STANDARDS FOR PAYMENT TO NURSING FACILITIES AND INTERMEDIATE CARE FACILITIES FOR THE MENTALLY RETARDED Provider Agreements § 442.12 Provider agreement: General... 42 Public Health 4 2010-10-01 2010-10-01 false Provider agreement: General requirements....

  9. 5 CFR 334.106 - Requirement for written agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Requirement for written agreement. 334... TEMPORARY ASSIGNMENTS UNDER THE INTERGOVERNMENTAL PERSONNEL ACT (IPA) § 334.106 Requirement for written... a written agreement recording the obligations and responsibilities of the parties, as specified in...

  10. 5 CFR 334.106 - Requirement for written agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Requirement for written agreement. 334... TEMPORARY ASSIGNMENTS UNDER THE INTERGOVERNMENTAL PERSONNEL ACT (IPA) § 334.106 Requirement for written... a written agreement recording the obligations and responsibilities of the parties, as specified in...

  11. Agreements with the Asian Development Bank

    EPA Pesticide Factsheets

    EPA and the Asian Development Bank cooperate to reinforce Asian countries which are now strengthening their environmental laws, ministries, and compliance mechanisms. Download agreements with the Asian Development Bank on this page.

  12. Cooperative research and development agreements at METC

    SciTech Connect

    Ludlow, J.C.; Jarr, L.A.; Anderson, R.J.

    1995-06-01

    The Federal Technology Transfer Act of 1986 (P.L. 99-502) provided a new mechanism for joint research between private parties and the Morgantown Energy Technology Center (METC). Joint projects under this law are called Cooperative Research And Development Agreements (CRADAs) and are simply agreements between METC and the private sector to work together on a mutually beneficial project. Of primary interest to METC is the development and deployment of: (1) clean, efficient power generation technologies, (2) technologies for the characterization and exploitation of the Nation`s natural gas resource, and (3) environmental remediation technologies.

  13. 24 CFR 266.505 - Regulatory agreement requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... AUTHORITIES HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.505 Regulatory agreement requirements. (a) General. (1) The HFA... capital needs. (3) Maintain the project as affordable housing, as defined in § 266.5. (4) Continue to...

  14. 24 CFR 266.505 - Regulatory agreement requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AUTHORITIES HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.505 Regulatory agreement requirements. (a) General. (1) The HFA... capital needs. (3) Maintain the project as affordable housing, as defined in § 266.5. (4) Continue to...

  15. 24 CFR 266.505 - Regulatory agreement requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... AUTHORITIES HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.505 Regulatory agreement requirements. (a) General. (1) The HFA... capital needs. (3) Maintain the project as affordable housing, as defined in § 266.5. (4) Continue to...

  16. 24 CFR 266.505 - Regulatory agreement requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... AUTHORITIES HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.505 Regulatory agreement requirements. (a) General. (1) The HFA... capital needs. (3) Maintain the project as affordable housing, as defined in § 266.5. (4) Continue to...

  17. 24 CFR 266.505 - Regulatory agreement requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... AUTHORITIES HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.505 Regulatory agreement requirements. (a) General. (1) The HFA... capital needs. (3) Maintain the project as affordable housing, as defined in § 266.5. (4) Continue to...

  18. 40 CFR 35.3135 - Specific capitalization grant agreement requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Specific capitalization grant agreement requirements. 35.3135 Section 35.3135 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE State Water Pollution Control Revolving Funds §...

  19. 40 CFR 35.3135 - Specific capitalization grant agreement requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Specific capitalization grant agreement requirements. 35.3135 Section 35.3135 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE State Water Pollution Control Revolving Funds §...

  20. 40 CFR 35.3135 - Specific capitalization grant agreement requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Specific capitalization grant agreement requirements. 35.3135 Section 35.3135 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE State Water Pollution Control Revolving Funds §...

  1. 40 CFR 35.3135 - Specific capitalization grant agreement requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Specific capitalization grant agreement requirements. 35.3135 Section 35.3135 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE State Water Pollution Control Revolving Funds §...

  2. 40 CFR 35.3135 - Specific capitalization grant agreement requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Specific capitalization grant agreement requirements. 35.3135 Section 35.3135 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE State Water Pollution Control Revolving Funds §...

  3. 20 CFR 416.1910 - Requirements for interim assistance agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... part on payment of benefits if the State cannot pay it to you (for example, you die or you move and the... effect between us and the State if we are to repay the State for interim assistance. The following requirements must be part of the agreement: (a) SSA to repay the State. We must agree to repay the State...

  4. 20 CFR 416.1910 - Requirements for interim assistance agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... part on payment of benefits if the State cannot pay it to you (for example, you die or you move and the... effect between us and the State if we are to repay the State for interim assistance. The following requirements must be part of the agreement: (a) SSA to repay the State. We must agree to repay the State...

  5. 20 CFR 416.1910 - Requirements for interim assistance agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... part on payment of benefits if the State cannot pay it to you (for example, you die or you move and the... effect between us and the State if we are to repay the State for interim assistance. The following requirements must be part of the agreement: (a) SSA to repay the State. We must agree to repay the State...

  6. 20 CFR 416.1910 - Requirements for interim assistance agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... part on payment of benefits if the State cannot pay it to you (for example, you die or you move and the... effect between us and the State if we are to repay the State for interim assistance. The following requirements must be part of the agreement: (a) SSA to repay the State. We must agree to repay the State...

  7. 20 CFR 416.1910 - Requirements for interim assistance agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... part on payment of benefits if the State cannot pay it to you (for example, you die or you move and the... effect between us and the State if we are to repay the State for interim assistance. The following requirements must be part of the agreement: (a) SSA to repay the State. We must agree to repay the State...

  8. 42 CFR 423.552 - Novation agreement requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 3 2013-10-01 2013-10-01 false Novation agreement requirements. 423.552 Section 423.552 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM (CONTINUED) VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Effect...

  9. 42 CFR 423.552 - Novation agreement requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 3 2014-10-01 2014-10-01 false Novation agreement requirements. 423.552 Section 423.552 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM (CONTINUED) VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Effect...

  10. 42 CFR 423.552 - Novation agreement requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Novation agreement requirements. 423.552 Section 423.552 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Effect of Change...

  11. 42 CFR 423.552 - Novation agreement requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 3 2011-10-01 2011-10-01 false Novation agreement requirements. 423.552 Section 423.552 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Effect of Change...

  12. 42 CFR 423.552 - Novation agreement requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 3 2012-10-01 2012-10-01 false Novation agreement requirements. 423.552 Section 423.552 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM (CONTINUED) VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Effect...

  13. 42 CFR 431.107 - Required provider agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... facilities, providers of home health care and personal care services, hospices, and HMOs specified in part... 42 Public Health 4 2010-10-01 2010-10-01 false Required provider agreement. 431.107 Section 431... (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STATE ORGANIZATION AND GENERAL ADMINISTRATION...

  14. 40 CFR 35.6250 - Support agency Cooperative Agreement requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Support Agency Cooperative Agreements § 35.6250 Support agency... submit a non-site-specific budget for support agency activities. (b) Cooperative Agreement...

  15. 40 CFR 35.6250 - Support agency Cooperative Agreement requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Support Agency Cooperative Agreements § 35.6250 Support agency... submit a non-site-specific budget for support agency activities. (b) Cooperative Agreement...

  16. 40 CFR 35.6250 - Support agency Cooperative Agreement requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Support Agency Cooperative Agreements § 35.6250 Support agency... submit a non-site-specific budget for support agency activities. (b) Cooperative Agreement...

  17. 40 CFR 35.6250 - Support agency Cooperative Agreement requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Support Agency Cooperative Agreements § 35.6250 Support agency... submit a non-site-specific budget for support agency activities. (b) Cooperative Agreement...

  18. 40 CFR 35.6250 - Support agency Cooperative Agreement requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Support Agency Cooperative Agreements § 35.6250 Support agency... submit a non-site-specific budget for support agency activities. (b) Cooperative Agreement...

  19. 22 CFR 124.8 - Clauses required both in manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... subject to all United States laws and regulations relating to exports and to all administrative acts of the U.S. Government pursuant to such laws and regulations.” (3) “The parties to this agreement agree that the obligations contained in this agreement shall not affect the performance of any...

  20. 22 CFR 124.9 - Additional clauses required only in manufacturing license agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... manufacturing license agreements. 124.9 Section 124.9 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL... Additional clauses required only in manufacturing license agreements. (a) Clauses for all manufacturing license agreements. The following clauses must be included only in manufacturing license agreements:...

  1. 22 CFR 124.9 - Additional clauses required only in manufacturing license agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... manufacturing license agreements. 124.9 Section 124.9 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL... Additional clauses required only in manufacturing license agreements. (a) Clauses for all manufacturing license agreements. The following clauses must be included only in manufacturing license agreements:...

  2. 22 CFR 124.9 - Additional clauses required only in manufacturing license agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... manufacturing license agreements. 124.9 Section 124.9 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL... Additional clauses required only in manufacturing license agreements. (a) Clauses for all manufacturing license agreements. The following clauses must be included only in manufacturing license agreements:...

  3. 22 CFR 124.9 - Additional clauses required only in manufacturing license agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... manufacturing license agreements. 124.9 Section 124.9 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL... Additional clauses required only in manufacturing license agreements. (a) Clauses for all manufacturing license agreements. The following clauses must be included only in manufacturing license agreements:...

  4. Information System Requirements Determination: Factors Impeding Stakeholders from Reaching Common Understandings and Agreements on Requirements

    ERIC Educational Resources Information Center

    Gissel, Richard L.

    2010-01-01

    Information system implementations require developers to first know what they must create and then determine how best to create it. The requirements determination phase of the system development life cycle typically determines what functions a system must perform and how well it must accomplish required functions. Implementation success depends on…

  5. 46 CFR 535.502 - Agreements subject to the Information Form requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 9 2011-10-01 2011-10-01 false Agreements subject to the Information Form requirements... OF 1984 Information Form Requirements § 535.502 Agreements subject to the Information Form... losses; or (5) The discussion of, or agreement on, any service contract matter; and (c)...

  6. 46 CFR 535.502 - Agreements subject to the Information Form requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 9 2014-10-01 2014-10-01 false Agreements subject to the Information Form requirements... OF 1984 Information Form Requirements § 535.502 Agreements subject to the Information Form... losses; or (5) The discussion of, or agreement on, any service contract matter; and (c)...

  7. 26 CFR 1.367(a)-8 - Gain recognition agreement requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... of gain subject to the gain recognition agreement at the time of the gain recognition event; (ii) The... 26 Internal Revenue 4 2013-04-01 2013-04-01 false Gain recognition agreement requirements. 1.367(a... recognition agreement requirements. (a) Scope. This section provides the terms and conditions for a...

  8. 26 CFR 1.367(a)-8 - Gain recognition agreement requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... of gain subject to the gain recognition agreement at the time of the gain recognition event; (ii) The... 26 Internal Revenue 4 2014-04-01 2014-04-01 false Gain recognition agreement requirements. 1.367(a... recognition agreement requirements. (a) Scope. This section provides the terms and conditions for a...

  9. Against Permitted Exploitation in Developing World Research Agreements.

    PubMed

    Wenner, Danielle M

    2016-04-01

    This paper examines the moral force of exploitation in developing world research agreements. Taking for granted that some clinical research which is conducted in the developing world but funded by developed world sponsors is exploitative, it asks whether a third party would be morally justified in enforcing limits on research agreements in order to ensure more fair and less exploitative outcomes. This question is particularly relevant when such exploitative transactions are entered into voluntarily by all relevant parties, and both research sponsors and host communities benefit from the resulting agreements. I show that defenders of the claim that exploitation ought to be permitted rely on a mischaracterization of certain forms of interference as unjustly paternalistic and two dubious empirical assumptions about the results of regulation. The view I put forward is that by evaluating a system of constraints on international research agreements, rather than individual transaction-level interference, we can better assess the alternatives to permitting exploitative research agreements.

  10. 44 CFR 332.2 - Developing voluntary agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Developing voluntary agreements. 332.2 Section 332.2 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS VOLUNTARY AGREEMENTS UNDER SECTION 708 OF THE DEFENSE...

  11. 40 CFR 35.3550 - Specific capitalization grant agreement requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... requirements. 35.3550 Section 35.3550 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND... payments. A State must agree to accept capitalization grant payments in accordance with a payment schedule... made in an amount equal to the amount of each capitalization grant payment and accompanying State...

  12. Co-Development Agreements | NCI Technology Transfer Center | TTC

    Cancer.gov

    The National Cancer Institute's TTC uses three different co-development agreements to help industry and academia interact and partner with National Institutes of Health laboratories and scientists to support technology development activities. | [google6f4cd5334ac394ab.html

  13. 47 CFR 80.161 - Operator requirements of the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Operator requirements of the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Operator Requirements Ship Station Operator Requirements § 80.161 Operator requirements of the Great Lakes Radio Agreement. Each ship subject to the...

  14. 47 CFR 80.161 - Operator requirements of the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Operator requirements of the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Operator Requirements Ship Station Operator Requirements § 80.161 Operator requirements of the Great Lakes Radio Agreement. Each ship subject to the...

  15. 47 CFR 80.161 - Operator requirements of the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Operator requirements of the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Operator Requirements Ship Station Operator Requirements § 80.161 Operator requirements of the Great Lakes Radio Agreement. Each ship subject to the...

  16. 47 CFR 80.161 - Operator requirements of the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Operator requirements of the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Operator Requirements Ship Station Operator Requirements § 80.161 Operator requirements of the Great Lakes Radio Agreement. Each ship subject to the...

  17. 47 CFR 80.161 - Operator requirements of the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Operator requirements of the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Operator Requirements Ship Station Operator Requirements § 80.161 Operator requirements of the Great Lakes Radio Agreement. Each ship subject to the...

  18. Developing country finance in a post-2020 global climate agreement

    NASA Astrophysics Data System (ADS)

    Hannam, Phillip M.; Liao, Zhenliang; Davis, Steven J.; Oppenheimer, Michael

    2015-11-01

    A central task for negotiators of the post-2020 global climate agreement is to construct a finance regime that supports low-carbon development in developing economies. As power sector investments between developing countries grow, the climate finance regime should incentivize the decarbonization of these major sources of finance by integrating them as a complement to the commitments of developed nations. The emergence of the Asian Infrastructure Investment Bank, South-South Cooperation Fund and other nascent institutions reveal the fissures that exist in rules and norms surrounding international finance in the power sector. Structuring the climate agreement in Paris to credit qualified finance from the developing world could have several advantages, including: (1) encouraging low-carbon cooperation between developing countries; (2) incentivizing emerging investors to prefer low-carbon investments; and (3) enabling more cost-effective attainment of national and global climate objectives. Failure to coordinate on standards now could hinder low-carbon development in the decades to come.

  19. FY2011 Progress Report: Agreement 8697 - NOx Sensor Development

    SciTech Connect

    Woo, L Y; Glass, R S

    2011-11-01

    Objectives are: (1) Develop an inexpensive, rapid-response, high-sensitivity and selective electrochemical sensor for oxides of nitrogen (NO{sub x}) for compression-ignition, direct-injection (CIDI) OBD II systems; (2) Explore and characterize novel, effective sensing methodologies based on impedance measurements and designs and manufacturing methods that are compatible with mass fabrication; and (3) Collaborate with industry in order to (ultimately) transfer the technology to a supplier for commercialization. Approach used is: (1) Use an ionic (O{sup 2-}) conducting ceramic as a solid electrolyte and metal or metal-oxide electrodes; (2) Correlate NO{sub x} concentration with changes in cell impedance; (3) Evaluate sensing mechanisms and aging effects on long-term performance using electrochemical techniques; and (4) Collaborate with Ford Research Center to optimize sensor performance and perform dynamometer and on-vehicle testing. Work in FY2011 focused on using an algorithm developed in FY2010 in a simplified strategy to demonstrate how data from controlled laboratory evaluation could be applied to data from real-world engine testing. The performance of a Au wire prototype sensor was evaluated in the laboratory with controlled gas compositions and in dynamometer testing with diesel exhaust. The laboratory evaluation indicated a nonlinear dependence of the NO{sub x} and O{sub 2} sensitivity with concentration. For both NO{sub x} and O{sub 2}, the prototype sensor had higher sensitivity at concentrations less than {approx}20 ppm and {approx}7%, respectively, compared to lower NO{sub x} and O{sub 2} sensitivity at concentrations greater than {approx}50 ppm and {approx}10.5%, respectively. Results in dynamometer diesel exhaust generally agreed with the laboratory results. Diesel exhaust after-treatment systems will likely require detection levels less than {approx}20 ppm in order to meet emission regulations. The relevant mathematical expressions for sensitivity in

  20. 14 CFR 203.3 - Filing requirements for adherence to Montreal Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Montreal Agreement. 203.3 Section 203.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF... DEFENSES § 203.3 Filing requirements for adherence to Montreal Agreement. All direct U.S. and foreign air... liability limitations of the Warsaw Convention and Hague Protocol approved by CAB Order E-23680, dated...

  1. 14 CFR 203.3 - Filing requirements for adherence to Montreal Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Montreal Agreement. 203.3 Section 203.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF... DEFENSES § 203.3 Filing requirements for adherence to Montreal Agreement. All direct U.S. and foreign air... liability limitations of the Warsaw Convention and Hague Protocol approved by CAB Order E-23680, dated...

  2. 14 CFR 203.3 - Filing requirements for adherence to Montreal Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Montreal Agreement. 203.3 Section 203.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF... DEFENSES § 203.3 Filing requirements for adherence to Montreal Agreement. All direct U.S. and foreign air... liability limitations of the Warsaw Convention and Hague Protocol approved by CAB Order E-23680, dated...

  3. 14 CFR 203.3 - Filing requirements for adherence to Montreal Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Montreal Agreement. 203.3 Section 203.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF... DEFENSES § 203.3 Filing requirements for adherence to Montreal Agreement. All direct U.S. and foreign air... liability limitations of the Warsaw Convention and Hague Protocol approved by CAB Order E-23680, dated...

  4. 14 CFR 203.3 - Filing requirements for adherence to Montreal Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Montreal Agreement. 203.3 Section 203.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF... DEFENSES § 203.3 Filing requirements for adherence to Montreal Agreement. All direct U.S. and foreign air... liability limitations of the Warsaw Convention and Hague Protocol approved by CAB Order E-23680, dated...

  5. 26 CFR 1.367(a)-8 - Gain recognition agreement requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... filing Form 8838 “Consent to Extend the Time to Assess Tax Under Section 367—Gain Recognition Agreement... time of the gain recognition event; (ii) The amount of gain recognized under the gain recognition... 26 Internal Revenue 4 2010-04-01 2010-04-01 false Gain recognition agreement requirements....

  6. 26 CFR 1.367(a)-8 - Gain recognition agreement requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... filing Form 8838 “Consent to Extend the Time to Assess Tax Under Section 367—Gain Recognition Agreement... time of the gain recognition event; (ii) The amount of gain recognized under the gain recognition... 26 Internal Revenue 4 2012-04-01 2012-04-01 false Gain recognition agreement requirements....

  7. 26 CFR 1.367(a)-8 - Gain recognition agreement requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... filing Form 8838 “Consent to Extend the Time to Assess Tax Under Section 367—Gain Recognition Agreement... time of the gain recognition event; (ii) The amount of gain recognized under the gain recognition... 26 Internal Revenue 4 2011-04-01 2011-04-01 false Gain recognition agreement requirements....

  8. 40 CFR 790.22 - Procedures for developing consent agreements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 33 2013-07-01 2013-07-01 false Procedures for developing consent agreements. 790.22 Section 790.22 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC... other respects. (9) Where a consensus exists, as described in paragraph (b)(8) of this...

  9. 48 CFR 552.236-83 - Requirement for a Project Labor Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... substantially the same as the following: Requirement for a Project Labor Agreement (SEP 1999) (a) Definition... mechanisms for labor-management cooperation on matters of mutual interest and concern, including...

  10. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Watch required by the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  11. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Watch required by the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  12. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Watch required by the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  13. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Watch required by the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  14. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Watch required by the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  15. Parent-teacher agreement on ADHD symptoms across development.

    PubMed

    Narad, Megan E; Garner, Annie A; Peugh, James L; Tamm, Leanne; Antonini, Tanya N; Kingery, Kathleen M; Simon, John O; Epstein, Jeffery N

    2015-03-01

    Parent-teacher agreement on attention-deficit/hyperactivity disorder (ADHD) symptom ratings ranges from low to moderate. Most studies evaluating parent-teacher agreement have not assessed measurement invariance across raters. Hence, it is unclear whether discordance across raters is due to differing ADHD constructs across raters or other factors (e.g., subjective differences across raters). Additionally, the effect of development on parent-teacher agreement is relatively unknown. To address these limitations, the present study used parent and teacher ADHD ratings from a large (N = 6,659) developmentally diverse (ages 4-17) sample. Using exploratory structural equation modeling on half the sample, and then confirmatory factor analysis (CFA) on the other half of the sample, confirmed a 2-factor structure with significant cross-loadings for the 18 ADHD symptoms. CFA invariance analyses demonstrated that the 2-factor symptom structure was similar across raters and age groups. After confirming measurement invariance, the correlation between latent factors within and across raters was examined for each age group as well as across age groups. Parents reported greater severity of ADHD symptoms than did teachers, and both parents and teachers reported higher levels of hyperactivity/impulsivity in younger children than in older children and consistent levels of inattention across development. Finally, correlations between parent-teacher ratings of like factors were weak for inattention and moderate-strong for hyperactivity/impulsivity, and the magnitude of parent-teacher agreement did not vary across development. In conclusion, while parent and teacher ratings of ADHD behaviors are only weakly to moderately correlated, each reporter provides unique and valid clinical information as it relates to ADHD symptom presentation.

  16. Recommendations and Privacy Requirements for a Bring-Your-Own-Device User Policy and Agreement

    DTIC Science & Technology

    2015-03-01

    establishes the USMC’s policy regarding acceptable use of personally-owned mobile devices within the BYOD program. This BYOD agreement aims to...AND PRIVACY REQUIREMENTS FOR A BRING-YOUR-OWN-DEVICE USER POLICY AND AGREEMENT by Chad R. Wedel Andrew T. Michalowicz March 2015 Thesis...author and do not reflect the official policy or position of the Department of Defense or the U.S. Govemment. IRB Protocol number NIA 12a

  17. Reduction of Conflicts in Mining Development Using "Good Neighbor Agreements"

    NASA Astrophysics Data System (ADS)

    Masaitis, A.

    2013-05-01

    New environmental and social challenges for the mining industry in both developed and developing countries show the obvious need to implement "responsible" mining practices that include improved community involvement. Good Neighbor Agreements (GNA's) are a relatively new mechanism for improving communication and trust between a mining company and the community. The focus of a GNA will be to provide a written and enforceable agreement, negotiated between the concerned public and the respective mining company to respond to concerns from the public, and also provide a mechanism for conflict resolution, when there is mutual benefit to maintain a working relationship. Development of GNA's, a recently evolving process that promotes environmentally sound relationships between mines and the surrounding communities. Modify and apply the resulting GNA formulas to the developing countries and countries with transitional economies. This is particularly important for countries that have poorly functioning regulatory systems that cannot guarantee a healthy and safe environment for the communities. The fundamental questions addressed by this research. 1. This is a three-year research project started in August 2012 at the University of Nevada, Reno (UNR) to develop a Good Neighbor Agreements standards as well as to investigate the details of mine development. 2. Identify spheres of possible cooperation between mining companies, government organizations, and the Non-Governmental Organizations (NGO's). Use this cooperation to develop international standards for the GNA, to promote exchange of environmental information, and exchange of successful environmental, health, and safety practices between mining operations from different countries. Discussion: The Good Neighbor Agreement currently evolving will address the following: 1. Provide an economically viable mechanism for developing a partnership between mining operations and the local communities that will increase mining industry

  18. 26 CFR 36.3121(l)(10)-1 - Requirements in respect of liability under agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... agreement. 36.3121(l)(10)-1 Section 36.3121(l)(10)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT... OF EMPLOYEES OF FOREIGN SUBSIDIARIES § 36.3121(l)(10)-1 Requirements in respect of liability under... provided in § 36.3121(l)(1)-1....

  19. 26 CFR 36.3121(l)(10)-1 - Requirements in respect of liability under agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... agreement. 36.3121(l)(10)-1 Section 36.3121(l)(10)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT... OF EMPLOYEES OF FOREIGN SUBSIDIARIES § 36.3121(l)(10)-1 Requirements in respect of liability under... provided in § 36.3121(l)(1)-1....

  20. 26 CFR 36.3121(l)(10)-1 - Requirements in respect of liability under agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... agreement. 36.3121(l)(10)-1 Section 36.3121(l)(10)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT... OF EMPLOYEES OF FOREIGN SUBSIDIARIES § 36.3121(l)(10)-1 Requirements in respect of liability under... provided in § 36.3121(l)(1)-1....

  1. 26 CFR 36.3121(l)(10)-1 - Requirements in respect of liability under agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... agreement. 36.3121(l)(10)-1 Section 36.3121(l)(10)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT... OF EMPLOYEES OF FOREIGN SUBSIDIARIES § 36.3121(l)(10)-1 Requirements in respect of liability under... provided in § 36.3121(l)(1)-1....

  2. 26 CFR 36.3121(l)(10)-1 - Requirements in respect of liability under agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... agreement. 36.3121(l)(10)-1 Section 36.3121(l)(10)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT... OF EMPLOYEES OF FOREIGN SUBSIDIARIES § 36.3121(l)(10)-1 Requirements in respect of liability under... provided in § 36.3121(l)(1)-1....

  3. 14 CFR 213.7 - Filing requirements for adherence to Montreal Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Filing requirements for adherence to Montreal Agreement. 213.7 Section 213.7 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF... part 203 of this chapter. That form can be obtained from the Foreign Air Carrier Licensing Division...

  4. 32 CFR 720.6 - Agreement required prior to delivery to State authorities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 5 2011-07-01 2011-07-01 false Agreement required prior to delivery to State authorities. 720.6 Section 720.6 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL DELIVERY OF PERSONNEL; SERVICE OF PROCESS AND SUBPOENAS; PRODUCTION OF OFFICIAL RECORDS Delivery of Personnel § 720.6...

  5. 48 CFR 801.602-74 - Review requirements for an interagency agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Review requirements for an interagency agreement. 801.602-74 Section 801.602-74 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION REGULATION SYSTEM Career...

  6. 43 CFR 414.4 - Reporting requirements and accounting under Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true Reporting requirements and accounting under Storage and Interstate Release Agreements. 414.4 Section 414.4 Public Lands: Interior Regulations Relating to Public Lands BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO...

  7. 25 CFR 84.004 - Are there types of contracts and agreements that do not require Secretarial approval under this...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Are there types of contracts and agreements that do not... there types of contracts and agreements that do not require Secretarial approval under this part? Yes, the following types of contracts or agreements do not require Secretarial approval under this part:...

  8. 25 CFR 84.004 - Are there types of contracts and agreements that do not require Secretarial approval under this...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Are there types of contracts and agreements that do not... there types of contracts and agreements that do not require Secretarial approval under this part? Yes, the following types of contracts or agreements do not require Secretarial approval under this part:...

  9. 25 CFR 84.004 - Are there types of contracts and agreements that do not require Secretarial approval under this...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Are there types of contracts and agreements that do not... there types of contracts and agreements that do not require Secretarial approval under this part? Yes, the following types of contracts or agreements do not require Secretarial approval under this part:...

  10. 25 CFR 84.004 - Are there types of contracts and agreements that do not require Secretarial approval under this...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Are there types of contracts and agreements that do not... there types of contracts and agreements that do not require Secretarial approval under this part? Yes, the following types of contracts or agreements do not require Secretarial approval under this part:...

  11. 25 CFR 84.004 - Are there types of contracts and agreements that do not require Secretarial approval under this...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Are there types of contracts and agreements that do not... there types of contracts and agreements that do not require Secretarial approval under this part? Yes, the following types of contracts or agreements do not require Secretarial approval under this part:...

  12. 40 CFR Appendix A to Subpart E of... - Schedule for Developing Consent Agreements and Test Rules

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Agreements and Test Rules A Appendix A to Subpart E of Part 790 Protection of Environment ENVIRONMENTAL... AGREEMENTS AND TEST RULES Exemptions From Test Rules Pt. 790, Subpt. E, App. A Appendix A to Subpart E of... required under section 4(a) of TSCA but agreement cannot be reached in timely manner on a consent...

  13. 42 CFR 433.151 - Cooperative agreements and incentive payments-State plan requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) A State plan must provide for entering into written cooperative agreements for enforcement of rights... 42 Public Health 4 2010-10-01 2010-10-01 false Cooperative agreements and incentive payments-State... Third Party Liability Cooperative Agreements and Incentive Payments § 433.151 Cooperative agreements...

  14. Dual Shell Pressure Balanced Reactor Vessel cooperative research and development agreement with Innotek, Inc., Final report

    SciTech Connect

    Robertus, R.J.; Fassbender, A.G.; Deverman, G.S.

    1995-04-01

    The Department of Energy`s Office of Energy Research (OER) has provided support for the development of several chemical processes, including supercritical water oxidation, liquefaction, and aqueous hazardous waste destruction, where chemical and phase transformations are conducted at high pressure and temperature. These and many other commercial processes require a pressure vessel capable of operating in a corrosive environment where safety and economy are important requirements. This document details a cooperative research and development agreement for a novel Dual Shell Pressure Balanced Vessel (DSPBV) which could solve a number of these problems. The Technology could be immediately useful in continuing commercialization of an R&D 100 award-winning technology, Sludge-to-oil Reactor System (STORS), originally developed through funding by OER.

  15. 48 CFR 52.225-12 - Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...: Notice of Buy American Act Requirement—Construction Materials Under Trade Agreements (FEB 2009) (a... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements. 52.225-12 Section 52.225-12 Federal...

  16. 20 CFR 411.410 - Does each referral from an EN to a State VR agency require its own agreement?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Does each referral from an EN to a State VR agency require its own agreement? 411.410 Section 411.410 Employees' Benefits SOCIAL SECURITY...' Participation Agreements Between Employment Networks and State Vr Agencies § 411.410 Does each referral from...

  17. 20 CFR 411.410 - Does each referral from an EN to a State VR agency require its own agreement?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Does each referral from an EN to a State VR agency require its own agreement? 411.410 Section 411.410 Employees' Benefits SOCIAL SECURITY...' Participation Agreements Between Employment Networks and State Vr Agencies § 411.410 Does each referral from...

  18. 17 CFR 240.3a69-3 - Books and records requirements for security-based swap agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Books and records requirements... § 240.3a69-3 Books and records requirements for security-based swap agreements. (a) A person registered... and regulations thereunder: (1) Shall not be required to keep and maintain additional books...

  19. 17 CFR 240.3a69-3 - Books and records requirements for security-based swap agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Books and records requirements... § 240.3a69-3 Books and records requirements for security-based swap agreements. (a) A person registered... and regulations thereunder: (1) Shall not be required to keep and maintain additional books...

  20. Energy requirements of development projects

    SciTech Connect

    Jones, D.W.; Samuels, G. Jr.

    1988-01-01

    This report focuses on the energy requirements of pumped irrigation and cement plants as examples of the energy operating requirements of large development projects. Based on conservative assumptions about the nearness of the water table to the surface and the efficiency of operating pumping systems, using pumped irrigation to increase by 5% the arable land area of the countries studied would require energy equivalent to 4-1/2% to 8-1/2% of 1980 energy imports or commercial energy consumption of four of the countries; Somalia and Chad would require 15% and 22% of their 1980 oil import or consumption levels - partly because of relatively large, marginally arable land areas and partly because of low energy imports (commercial consumption). The introduction of one or (at most) two moderate-sized cement plants into five West African countries and Sudan requires from 12% to 40% of those countries' 1980 national commercial energy consumption for their operation. These calculations assume high levels of maintenance and developed country standards of fuel efficient operation; therefore actual fuel requirements are likely to be higher. The countries studied have few or no domestic fuel supply options other than imports. 2 figs., 2 tabs.

  1. 40 CFR 35.1615 - Substate agreements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... agencies. The agreement shall be developed, administered and approved in accordance with the provisions of... this subchapter. The agreement shall specify outputs, milestone schedule, and the budget required...

  2. Development of an energy conservation voluntary agreement pilot project in the steel sector in Shandong

    SciTech Connect

    Price, Lynn; Yun, Jiang; Worrell, Ernst; Wenwei, Du; Sinton, Jonathan E.

    2004-02-05

    China faces a significant challenge in the years ahead to continue to provide essential materials and products for a rapidly-growing economy while addressing pressing environmental concerns. Energy is a fundamental element of the national economy and the conditions of its use have a direct impact on China's ability to reach its sustainable development goals. China's industrial sector, which accounts for over 70 percent of the nation's total energy consumption each year, provides materials such as steel and cement that build the nation's roads, bridges, homes, offices and other buildings. Industrial products include bicycles, cars, buses, trains, ships, office equipment, appliances, furniture, packaging, pharmaceuticals, and many other components of everyday life in an increasingly modern society. This vital production of materials and products, however, comes with considerable problems. China's industrial sector is heavily dependent on the country's abundant, yet polluting, coal resources. Industrial production locally pollutes the air with emissions of particulates, carbon monoxide, sulfur dioxide, and nitrogen oxides, uses scarce water and oil resources, emits greenhouse gases contributing to the warming global atmosphere, and often produces hazardous and polluting wastes. Fostering innovative approaches to reduce the use of polluting energy resources and to diminish pollution from industrial production that are tailored to China's emerging market-based economy is one of the most important challenges facing the nation today. The pressures of rapid industrial production growth, continued environmental degradation, and increased competition create a situation that calls for a strategically-planned evolution of China's industries into world-class production facilities that are competitive, energy-efficient and less polluting. Such a transition requires the complete commitment of industrial enterprises and the government to work together to transform the industrial

  3. 40 CFR Appendix C-1 to Subpart E... - Required Provisions-Consulting Engineering Agreements

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Engineering Agreements C Appendix C-1 to Subpart E of Part 35 Protection of Environment ENVIRONMENTAL... Provisions—Consulting Engineering Agreements 1. General 2. Responsibility of the Engineer 3. Scope of Work 4... drawings, designs, specifications, reports, and incidental engineering work or materials...

  4. 40 CFR Appendix C-1 to Subpart E... - Required Provisions-Consulting Engineering Agreements

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Engineering Agreements C Appendix C-1 to Subpart E of Part 35 Protection of Environment ENVIRONMENTAL... Provisions—Consulting Engineering Agreements 1. General 2. Responsibility of the Engineer 3. Scope of Work 4... drawings, designs, specifications, reports, and incidental engineering work or materials...

  5. 10 CFR 150.31 - Requirements for Agreement State regulation of byproduct material.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... REGULATORY AUTHORITY IN AGREEMENT STATES AND IN OFFSHORE WATERS UNDER SECTION 274 Enforcement § 150.31...) Excavation; (6) Erection of support buildings (e.g., construction equipment storage sheds, warehouse and...

  6. 10 CFR 150.31 - Requirements for Agreement State regulation of byproduct material.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... REGULATORY AUTHORITY IN AGREEMENT STATES AND IN OFFSHORE WATERS UNDER SECTION 274 Enforcement § 150.31...) Excavation; (6) Erection of support buildings (e.g., construction equipment storage sheds, warehouse and...

  7. 10 CFR 150.31 - Requirements for Agreement State regulation of byproduct material.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... REGULATORY AUTHORITY IN AGREEMENT STATES AND IN OFFSHORE WATERS UNDER SECTION 274 Enforcement § 150.31...) Excavation; (6) Erection of support buildings (e.g., construction equipment storage sheds, warehouse and...

  8. 48 CFR 801.602-74 - Review requirements for an interagency agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... officer or a contracting officer at the VA National Acquisition Center or the Denver Acquisition and Logistics Center may sign an interagency agreement if the dollar threshold is within the contracting...

  9. 48 CFR 801.602-74 - Review requirements for an interagency agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... officer or a contracting officer at the VA National Acquisition Center or the Denver Acquisition and Logistics Center may sign an interagency agreement if the dollar threshold is within the contracting...

  10. 48 CFR 801.602-74 - Review requirements for an interagency agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... officer or a contracting officer at the VA National Acquisition Center or the Denver Acquisition and Logistics Center may sign an interagency agreement if the dollar threshold is within the contracting...

  11. 48 CFR 801.602-74 - Review requirements for an interagency agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... officer or a contracting officer at the VA National Acquisition Center or the Denver Acquisition and Logistics Center may sign an interagency agreement if the dollar threshold is within the contracting...

  12. 48 CFR 52.222-33 - Notice of Requirement for Project Labor Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) Definitions. “Labor organization” and “project labor agreement,” as used in this provision, are defined in the... cooperation on matters of mutual interest and concern, including productivity, quality of work, safety,...

  13. 76 FR 25362 - Cooperative Research and Development Agreement: Butanol Fuel Blend Usage With Marine Outboard...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-04

    ... SECURITY Coast Guard Cooperative Research and Development Agreement: Butanol Fuel Blend Usage With Marine... Agreement (CRADA) to identify and investigate the use of butanol fuel blends within marine outboard engines... butanol fuel blends with marine outboard engines, with the overarching goal of reducing their...

  14. Global trade requirements and compliance with World Trade Organization agreements: the role of tracing animals and animal products.

    PubMed

    Wilson, D W; Beers, P T

    2001-08-01

    The use of a measure incorporating traceability that directly or indirectly affects international trade is permitted under the World Trade Organization Agreement on the Application of Sanitary and Phytosanitary Measures, provided that the measure is applied in accordance with the provisions of the Agreement. These provisions state that the measure must be necessary, scientifically justified, no more trade restrictive than required and consistent with the appropriate level of protection of the importing country. If requested, importing countries are required to assess claims by exporting countries regarding an alternative measure(s) providing an equivalent level of protection or with regard to regionalisation.

  15. 77 FR 74634 - Department of Commerce Pre-Award Notification Requirements for Grants and Cooperative Agreements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-17

    ... telecommunications and information. It is the policy of the DOC to seek full and open competition for awards of... agreements: ] 1. Federal Policies and Procedures. Applicants, recipients and subrecipients are subject to all Federal laws and Federal and DOC policies, regulations, and procedures applicable to Federal...

  16. 12 CFR 269.7 - Approval of agreement and required contents.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    .... 269.7 Section 269.7 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) POLICY ON LABOR RELATIONS FOR THE FEDERAL RESERVE BANKS § 269.7... provisions of applicable laws and Federal Reserve System rules and regulations, and the agreement shall...

  17. 12 CFR 269.7 - Approval of agreement and required contents.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    .... 269.7 Section 269.7 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM POLICY ON LABOR RELATIONS FOR THE FEDERAL RESERVE BANKS § 269.7 Approval of... Federal Reserve System rules and regulations, and the agreement shall at all times be applied subject...

  18. 12 CFR 269.7 - Approval of agreement and required contents.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .... 269.7 Section 269.7 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) POLICY ON LABOR RELATIONS FOR THE FEDERAL RESERVE BANKS § 269.7... provisions of applicable laws and Federal Reserve System rules and regulations, and the agreement shall...

  19. 12 CFR 269.7 - Approval of agreement and required contents.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .... 269.7 Section 269.7 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) POLICY ON LABOR RELATIONS FOR THE FEDERAL RESERVE BANKS § 269.7... provisions of applicable laws and Federal Reserve System rules and regulations, and the agreement shall...

  20. 12 CFR 269.7 - Approval of agreement and required contents.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... 269.7 Section 269.7 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM POLICY ON LABOR RELATIONS FOR THE FEDERAL RESERVE BANKS § 269.7 Approval of... Federal Reserve System rules and regulations, and the agreement shall at all times be applied subject...

  1. 77 FR 63221 - Waiver of Requirement To Enter Into a Reciprocal Waiver of Claims Agreement With All Customers

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-16

    ... Claims Agreement With All Customers AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of... the licensee implement a cross-waiver with each customer applies to all launches and reentries under... litigation, Congress required that all launch participants agree to waive claims against each other for...

  2. 78 FR 70392 - Waiver of Requirement To Enter Into a Reciprocal Waiver of Claims Agreement With All Customers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-25

    ... Agreement With All Customers for Orbital Sciences Corporation AGENCY: Federal Aviation Administration (FAA... cross-waiver with each customer applies to each of the NASA-sponsored CubeSat operators, all of whom... of catastrophic loss and litigation, Congress required that all launch participants agree to...

  3. 78 FR 57215 - Waiver of Requirement To Enter Into a Reciprocal Waiver of Claims Agreement With All Customers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-17

    ... Agreement With All Customers for Orbital Sciences Corporation AGENCY: Federal Aviation Administration (FAA... liability. Other than the NanoRacks and SSEP customers, all other customers as defined by 14 CFR 440.3 will execute the cross-waivers required by 14 CFR 440.17. The cross-waivers among Orbital and all...

  4. 45 CFR 205.58 - Income and eligibility information; specific agreements required between the State agency and the...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Income and eligibility information; specific agreements required between the State agency and the agency supplying the information. 205.58 Section 205.58 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND...

  5. 78 FR 42084 - Cooperative Agreement to Support the World Trade Organization's Standards and Trade Development...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-15

    ... HUMAN SERVICES Food and Drug Administration Cooperative Agreement to Support the World Trade...) to the World Trade Organization's (WTO) Standards and Trade Development Facility (STDF). DATES... partnership established by the Food and Agriculture Organization, World Organization for Animal Health,...

  6. 78 FR 3450 - Solicitation for a Cooperative Agreement: Development of Materials Specific to Lesbian, Gay...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE National Institute of Corrections Solicitation for a Cooperative Agreement: Development of Materials Specific to Lesbian, Gay, Bisexual, Transgender and Intersex (LGBTI) Offenders in Corrections...

  7. 78 FR 43925 - Solicitation for a Cooperative Agreement-Executive Excellence a Training and Development Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-22

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF JUSTICE.... Department of Justice. ACTION: Solicitation for a Cooperative Agreement. SUMMARY: The National Institute of... justice/corrections executive development program. In addition the applicant should demonstrate...

  8. 77 FR 25488 - Cooperative Research and Development Agreement: Federally Integrated Communications System

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-30

    ... Federal wireless system partner. This integrated communications system should provide for interoperability... SECURITY Coast Guard Cooperative Research and Development Agreement: Federally Integrated Communications System AGENCY: Coast Guard, DHS. ACTION: Notice of intent; request for public comments. SUMMARY:...

  9. 76 FR 44956 - Solicitation for a Cooperative Agreement; Correctional Health Care Executive Curriculum Development

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-27

    ... Cooperative Agreement; Correctional Health Care Executive Curriculum Development AGENCY: U.S. Department of... of a competency- based correctional health care executive curriculum to train two-person teams..., pharmaceutical, radiographic, infection control, long-term care, restorative therapy, health...

  10. 78 FR 57401 - Cooperative Research and Development Agreement (CRADA) Opportunity With the Department of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-18

    ... SECURITY Cooperative Research and Development Agreement (CRADA) Opportunity With the Department of Homeland Security for the Production and Associated Research of Purpose Bred Explosive Detection Canines AGENCY..., collection and analysis of quantitative behavior trait measurement; application of quantitative techniques...

  11. Requirement Development Process and Tools

    NASA Technical Reports Server (NTRS)

    Bayt, Robert

    2017-01-01

    Requirements capture the system-level capabilities in a set of complete, necessary, clear, attainable, traceable, and verifiable statements of need. Requirements should not be unduly restrictive, but should set limits that eliminate items outside the boundaries drawn, encourage competition (or alternatives), and capture source and reason of requirement. If it is not needed by the customer, it is not a requirement. They establish the verification methods that will lead to product acceptance. These must be reproducible assessment methods.

  12. Assessment of MSFCs Process for the Development and Activation of Space Act Agreement

    NASA Technical Reports Server (NTRS)

    Daugherty, Rachel

    2014-01-01

    Space Act Agreements (SAAs) are contractual agreements that NASA utilizes to form partnerships with researchers, industry, and academia to stimulate cutting-edge innovation within the science and technology communities. center dot This study assessed the current SAA development and activation process at Marshall Space Flight Center (MSFC) to determine if improvements could be implemented to increase productivity, decrease time to activation, and improve the quality of deliverables.

  13. 17 CFR 1.7 - Books and records requirements for security-based swap agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 1 2014-04-01 2014-04-01 false Books and records requirements... FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Definitions § 1.7 Books... not be required to keep and maintain additional books and records regarding security-based...

  14. 17 CFR 1.7 - Books and records requirements for security-based swap agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Books and records requirements... FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Definitions § 1.7 Books... not be required to keep and maintain additional books and records regarding security-based...

  15. 46 CFR 281.1 - Information and procedure required under liner operating-differential subsidy agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... paragraph (f)(7) of this section and consistent with the allocation bases provided in paragraph (f)(6) of... requirements for sub-schedules 3002 of the Maritime Administration Form 172. (6) Allocation bases. The allocation bases to be applied in preparation of vessel performance reports required by paragraph (f)(5)...

  16. 42 CFR 403.910 - Delayed publication for payments made under product research or development agreements and...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... medical supply. (b) Research or development agreement. The research or development agreement must include... research or development agreements and clinical investigations. 403.910 Section 403.910 Public Health... Interests § 403.910 Delayed publication for payments made under product research or development...

  17. Development and implementation of the Good Neighbor Agreement (GNA) practice in the USA sustainable mining development.

    NASA Astrophysics Data System (ADS)

    Masaitis, Alexandra

    2014-05-01

    New economic, environmental and social challenges for the mining industry in the USA show the need to implement "responsible" mining practices that include improved community involvement. Conflicts which occur in the US territory and with US mining companies around the world are now common between the mining proponents, NGO's and communities. These conflicts can sometimes be alleviated by early development of modes of communication, and a formal discussion format that allows airing of concerns and potential resolution of problems. One of the methods that can formalize this process is to establish a Good Neighbor Agreement (GNA), which deals specifically with challenges in relationships between mining operations and the local communities. It is a new practice related to mining operations that are oriented toward social needs and concerns of local communities that arise during the normal life of a mine, which can achieve sustainable mining practices. The GNA project being currently developed at the University of Nevada, USA in cooperation with the Newmont Mining Corporation has a goal of creating an open company/community dialog that will help identify and address sociological and environmental concerns associated with mining. Discussion: The Good Neighbor Agreement currently evolving will address the following: 1. Identify spheres of possible cooperation between mining companies, government organizations, and NGO's. 2. Provide an economically viable mechanism for developing a partnership between mining operations and the local communities that will increase mining industry's accountability and provide higher levels of confidence for the community that a mine is operated in a safe and sustainable manner. Implementation of the GNA can help identify and evaluate conflict criteria in mining/community relationships; determine the status of concerns; determine the role and responsibilities of stakeholders; analyze problem resolution feasibility; maintain the community

  18. 40 CFR Appendix C-1 to Subpart E... - Required Provisions-Consulting Engineering Agreements

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... practicable, provide for maximum use of structures, machines, products, materials, construction methods, and... require the use of structures, machines, products, materials, construction methods, equipment, or... PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction...

  19. 10 CFR 150.17a - Compliance with requirements of US/IAEA Safeguards Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... information on DOC/NRC Form AP-A and associated forms; (2) As required by the Additional Protocol, shall submit location information described in § 75.11 of this chapter on DOC/NRC Form AP-1 and associated... associated forms, and site information on DOC/NRC Form AP-A and associated forms; shall submit...

  20. 10 CFR 150.17a - Compliance with requirements of US/IAEA Safeguards Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... information on DOC/NRC Form AP-A and associated forms; (2) As required by the Additional Protocol, shall submit location information described in § 75.11 of this chapter on DOC/NRC Form AP-1 and associated... associated forms, and site information on DOC/NRC Form AP-A and associated forms; shall submit...

  1. 10 CFR 150.17a - Compliance with requirements of US/IAEA Safeguards Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... information on DOC/NRC Form AP-A and associated forms; (2) As required by the Additional Protocol, shall submit location information described in § 75.11 of this chapter on DOC/NRC Form AP-1 and associated... associated forms, and site information on DOC/NRC Form AP-A and associated forms; shall submit...

  2. 10 CFR 150.17a - Compliance with requirements of US/IAEA Safeguards Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... information on DOC/NRC Form AP-A and associated forms; (2) As required by the Additional Protocol, shall submit location information described in § 75.11 of this chapter on DOC/NRC Form AP-1 and associated... associated forms, and site information on DOC/NRC Form AP-A and associated forms; shall submit...

  3. 10 CFR 150.17a - Compliance with requirements of US/IAEA Safeguards Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... information on DOC/NRC Form AP-A and associated forms; (2) As required by the Additional Protocol, shall submit location information described in § 75.11 of this chapter on DOC/NRC Form AP-1 and associated... associated forms, and site information on DOC/NRC Form AP-A and associated forms; shall submit...

  4. 20 CFR 603.10 - What are the requirements for agreements?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Requirements. (1) For disclosures of confidential UC information under § 603.5(d)(2) (to a third party (other... met. (2) In the case of disclosures under § 603.5(d)(2) (to a third party (other than an agent) or... Department has determined, by notice published in the Federal Register, to have in place safeguards...

  5. Energy requirements for rural development

    SciTech Connect

    Jones, D.W.

    1988-06-01

    This study on the role of energy in the development of rural areas was originally conducted in the spring and summer of 1985. It was intended to serve as a background paper for the preparation of a program plan for the Office of Energy of the United States Agency for International Development. As such it begins with a brief overview of how rural development fits into national development, then offers a comprehensive framework for thinking about rural development in particular and the energy implications of the various components of rural development. Agriculture naturally comes to mind when rural areas are mentioned, but industry is an important component of rural activity as well. Consequently, both agricultural and nonagricultural energy use is discussed. Modernization of rural areas will change household, as well as production, energy use. However, household energy use is a veritable subject in its own right, with a large literature. Consequently, that topic is discussed in less detail than the production energy topics.

  6. 43 CFR 414.4 - Reporting requirements and accounting under Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Relating to Public Lands BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF INTENTIONALLY CREATED UNUSED APPORTIONMENT IN THE...

  7. 43 CFR 414.4 - Reporting requirements and accounting under Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Relating to Public Lands BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF INTENTIONALLY CREATED UNUSED APPORTIONMENT IN THE...

  8. 43 CFR 414.4 - Reporting requirements and accounting under Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Relating to Public Lands BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF INTENTIONALLY CREATED UNUSED APPORTIONMENT IN THE...

  9. 43 CFR 414.4 - Reporting requirements and accounting under Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Relating to Public Lands BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF INTENTIONALLY CREATED UNUSED APPORTIONMENT IN THE...

  10. Agreement that the PSD Regulations Require a Source to Commence Construction

    EPA Pesticide Factsheets

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  11. Space Act Agreement Maker (SAAM) With Electronic Routing System (ERouter) Developed

    NASA Technical Reports Server (NTRS)

    Stauber, Laurel J.

    2003-01-01

    Members of the Commercial Technology Office at the NASA Glenn Research Center have developed an exciting new tool that greatly reduces the lead time in creating and routing Space Act Agreements. The Space Act Agreement Maker (SAAM) is an e-government Web-based system that automates the initial drafting of Space Act Agreements by technical and program personnel. SAAM also is used for editing and will be used later for maintaining electronic copies of all Space Act Agreements. During the initial drafting, the software prompts NASA personnel proposing an agreement to answer questions regarding the agreement. On the basis of the answers, the software selects from a matrix of NASA standard clauses to produce a first draft of the agreement. The draft agreement and information submitted by the NASA personnel are electronically routed to Glenn s Commercial Technology Office for review and, where necessary, editing. The final version of the agreement, along with any supporting documentation, is then routed for electronic concurrence/approval to the necessary internal review participants using the electronic routing system (e-router). SAAM was developed cooperatively by Glenn s Commercial Technology Office and Glenn s Office of Chief Counsel. Currently, SAAM is being evaluated by the NASA Headquarters General Counsel Office for use at all NASA centers. This system allows for the effective processing of Space Act Agreements for NASA s internal and external customers. Document control is maintained by a database. With SAAM s electronic routing, review times can be reduced significantly, allowing Glenn to more rapidly establish partnerships with industry. Prior to the creation of SAAM, it took several hours to draft a Space Act Agreement. With SAAM in place, the document can be written in about 30 min. Using the e-router also saves time in determining where the agreement is in the routing process. The document can be tracked easily, and delays can be avoided. Important research

  12. 77 FR 31008 - Enforceable Consent Agreement Development for Two Cyclic Siloxanes; Solicitation of Interested...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-24

    ... proceeding with the negotiation of a consent agreement is an efficient means of developing the data, and now solicits additional persons with an interest in participating in the negotiations to notify EPA and announces a public meeting to initiate negotiations. DATES: The meeting to initiate ECA negotiations for...

  13. 34 CFR 363.50 - What collaborative agreements must the State develop?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false What collaborative agreements must the State develop? 363.50 Section 363.50 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION THE STATE...

  14. Assessing implementation mechanisms for an international agreement on research and development for health products.

    PubMed

    Hoffman, Steven J; Røttingen, John-Arne

    2012-11-01

    The Member States of the World Health Organization (WHO) are currently debating the substance and form of an international agreement to improve the financing and coordination of research and development (R&D) for health products that meet the needs of developing countries. In addition to considering the content of any possible legal or political agreement, Member States may find it helpful to reflect on the full range of implementation mechanisms available to bring any agreement into effect. These include mechanisms for states to make commitments, administer activities, manage financial contributions, make subsequent decisions, monitor each other's performance and promote compliance. States can make binding or non-binding commitments through conventions, contracts, declarations or institutional reforms. States can administer activities to implement their agreements through international organizations, sub-agencies, joint ventures or self-organizing processes. Finances can be managed through specialized multilateral funds, financial institutions, membership organizations or coordinated self-management. Decisions can be made through unanimity, consensus, equal voting, modified voting or delegation. Oversight can be provided by peer review, expert review, self-reports or civil society. Together, states should select their preferred options across categories of implementation mechanisms, each of which has advantages and disadvantages. The challenge lies in choosing the most effective combinations of mechanisms for supporting an international agreement (or set of agreements) that achieves collective aspirations in a way and at a cost that are both sustainable and acceptable to those involved. In making these decisions, WHO's Member States can benefit from years of experience with these different mechanisms in health and its related sectors.

  15. Uniform administrative requirements for grants and agreements with institutions of higher education, hospitals, other non-profit, and commercial organizations--Department of Commerce. Interim final rule.

    PubMed

    1998-09-04

    This interim final rule implements the revisions to the Office of Management and Budget (OMB) Circular A-110, "Uniform Administrative Requirements for Grants and Agreements With Institutions of Higher Education, Hospitals, and Other Non-Profit Organizations" which was published in the Federal Register on November 29, 1993. The revised Circular was developed by an interagency task force for governmentwide use in a model rule format to facilitate regulatory adoption by executive departments and agencies. In the published revised Circular, OMB specified as "required action" that Federal agencies responsible for awarding and administering grants and other agreements to recipients described therein, shall adopt the language of the Circular unless other provisions are required by Federal statute or exceptions or deviations are approved by OMB. This interim final rule adopts the provisions of the Circular and its language to the maximum extent feasible. However, minor changes were made to update the procedures, clarify the language, and make the language apply specifically to the DoC and its operating units. No changes are intended to deviate from the substance of Circular A-110. The Circular covers both grants and cooperative agreements made by Federal agencies and subawards, unless sections of the Circular specifically exclude subrecipients from coverage. Consistent with guidance provided in the Circular, DoC will apply its provisions to grants and agreements with institutions of higher education, hospitals, other nonprofit, and commercial organizations. The provisions of the interim final rule will also apply to foreign governments, organizations under the jurisdiction of foreign governments, and international organizations when appropriate.

  16. 2 CFR 200.24 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Cooperative agreement. 200.24 Section 200.24... REQUIREMENTS FOR FEDERAL AWARDS Acronyms and Definitions Acronyms § 200.24 Cooperative agreement. Cooperative... include: (1) A cooperative research and development agreement as defined in 15 U.S.C. 3710a; or (2)...

  17. A Best Practice for Developing Availability Guarantee Language in Photovoltaic (PV) O&M Agreements.

    SciTech Connect

    Klise, Geoffrey Taylor; Balfour, John

    2015-11-01

    This document outlines the foundation for developing language that can be utilized in an Equipment Availability Guarantee, typically included in an O&M services agreement between a PV system or plant owner and an O&M services provider, or operator. Many of the current PV O&M service agreement Availability Guarantees are based on contracts used for traditional power generation, which create challenges for owners and operators due to the variable nature of grid-tied photovoltaic generating technologies. This report documents language used in early PV availability guarantees and presents best practices and equations that can be used to more openly communicate how the reliability of the PV system and plant equipment can be expressed in an availability guarantee. This work will improve the bankability of PV systems by providing greater transparency into the equipment reliability state to all parties involved in an O&M services contract.

  18. Paris Agreement on Climate Change: A Booster to Enable Sustainable Global Development and Beyond.

    PubMed

    Bhore, Subhash Janardhan

    2016-11-14

    The global warming and its adverse effects on the atmosphere, the biosphere, the lithosphere, and the hydrosphere are obvious. Based on this fact, the international community is fully convinced that we need to fix the problem urgently for our survival, good health, and wellbeing. The aim of this article is to promote the awareness about the United Nations (UN) historic 'Paris Agreement on Climate Change (PACC)' which entered into-force on 4 November 2016. The expected impact of PACC on the global average temperature rise by 2100 as well as its role in enabling accomplishment of global sustainable development goals (SDGs) for the people and planet is also highlighted.

  19. Space power development impact on technology requirements

    NASA Technical Reports Server (NTRS)

    Cassidy, J. F.; Fitzgerald, T. J.; Gilje, R. I.; Gordon, J. D.

    1986-01-01

    The paper is concerned with the selection of a specific spacecraft power technology and the identification of technology development to meet system requirements. Requirements which influence the selection of a given technology include the power level required, whether the load is constant or transient in nature, and in the case of transient loads, the time required to recover the power, and overall system safety. Various power technologies, such as solar voltaic power, solar dynamic power, nuclear power systems, and electrochemical energy storage, are briefly described.

  20. Advanced Extravehicular Activity Pressure Garment Requirements Development

    NASA Technical Reports Server (NTRS)

    Ross, Amy

    2014-01-01

    The NASA Johnson Space Center advanced pressure garment technology development team is addressing requirements development for exploration missions. Lessons learned from the Z-2 high fidelity prototype development have reiterated that clear low-level requirements and verification methods reduce risk to the government, improve efficiency in pressure garment design efforts, and enable the government to be a smart buyer. The expectation is to provide requirements at the specification level that are validated so that their impact on pressure garment design is understood. Additionally, the team will provide defined verification protocols for the requirements. However, in reviewing exploration space suit high level requirements there are several gaps in the team's ability to define and verify related lower level requirements. This paper addresses the efforts in requirement areas such as mobility/fit/comfort and environmental protection (dust, radiation, plasma, secondary impacts) to determine the by what method the requirements can be defined and use of those methods for verification. Gaps exist at various stages. In some cases component level work is underway, but no system level effort has begun, in other cases no effort has been initiated to close the gap. Status of ongoing efforts and potential approaches to open gaps are discussed.

  1. SE Requirements Development Tool User Guide

    SciTech Connect

    Benson, Faith Ann

    2016-05-13

    The LANL Systems Engineering Requirements Development Tool (SERDT) is a data collection tool created in InfoPath for use with the Los Alamos National Laboratory’s (LANL) SharePoint sites. Projects can fail if a clear definition of the final product requirements is not performed. For projects to be successful requirements must be defined early in the project and those requirements must be tracked during execution of the project to ensure the goals of the project are met. Therefore, the focus of this tool is requirements definition. The content of this form is based on International Council on Systems Engineering (INCOSE) and Department of Defense (DoD) process standards and allows for single or collaborative input. The “Scoping” section is where project information is entered by the project team prior to requirements development, and includes definitions and examples to assist the user in completing the forms. The data entered will be used to define the requirements and once the form is filled out, a “Requirements List” is automatically generated and a Word document is created and saved to a SharePoint document library. SharePoint also includes the ability to download the requirements data defined in the InfoPath from into an Excel spreadsheet. This User Guide will assist you in navigating through the data entry process.

  2. 24 CFR 21.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Cooperative agreement. 21.620... Development GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) Definitions § 21.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  3. 24 CFR 21.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Cooperative agreement. 21.620... Development GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) Definitions § 21.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  4. 34 CFR 304.31 - Requirements for obtaining an exception or deferral to performance or repayment under an agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION SERVICE OBLIGATIONS UNDER SPECIAL EDUCATION-PERSONNEL DEVELOPMENT TO IMPROVE SERVICES AND RESULTS... 34 Education 2 2010-07-01 2010-07-01 false Requirements for obtaining an exception or deferral...

  5. 34 CFR 304.31 - Requirements for obtaining an exception or deferral to performance or repayment under an agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION SERVICE OBLIGATIONS UNDER SPECIAL EDUCATION-PERSONNEL DEVELOPMENT TO IMPROVE SERVICES AND RESULTS... 34 Education 2 2012-07-01 2012-07-01 false Requirements for obtaining an exception or deferral...

  6. 34 CFR 304.31 - Requirements for obtaining an exception or deferral to performance or repayment under an agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION SERVICE OBLIGATIONS UNDER SPECIAL EDUCATION-PERSONNEL DEVELOPMENT TO IMPROVE SERVICES AND RESULTS... 34 Education 2 2011-07-01 2010-07-01 true Requirements for obtaining an exception or deferral...

  7. Requirements development for a patient computing system.

    PubMed Central

    Wald, J. S.; Pedraza, L. A.; Reilly, C. A.; Murphy, M. E.; Kuperman, G. J.

    2001-01-01

    Critical parts of the software development life cycle are concerned with eliciting, understanding, and managing requirements. Though the literature on this subject dates back for several decades, practicing effective requirements development remains a current and challenging area. Some projects flourish with a requirements development process (RDP) that is implicit and informal, but this approach may be overly risky, particularly for large projects that involve multiple individuals, groups, and systems over time. At Partners HealthCare System in Boston, Massachusetts, we have applied a more formal approach for requirements development to the Patient Computing Project. The goal of the project is to create web-based software that connects patients electronically with their physician's offices and has the potential to improve care efficiency and quality. It is a large project, with over 500 function points. Like most technological innovation, the successful introduction of this system requires as much attention to understanding the business needs and workflow details as it does to technical design and implementation. This paper describes our RDP approach, and key business requirements discovered through this process. We believe that a formal RDP is essential, and that informatics as a field must include proficiencies in this area. PMID:11825282

  8. 76 FR 46849 - Solicitation for a Cooperative Agreement: Curriculum Development for Women Offenders; Developing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ... to agency leaders with roles in developing and/or implementing policy within their organizations. The... settings. The impact of these legislative changes is often not well understood by correctional policymakers... of risk. With the emergence of gender-informed research and knowledge, identifying areas of risk...

  9. Development of a cost-effectiveness analysis of leafy green marketing agreement irrigation water provisions.

    PubMed

    Jensen, Helen H; Pouliot, Sébastien; Wang, Tong; Jay-Russell, Michele T

    2014-06-01

    An analysis of the effectiveness of meeting the irrigation water provisions of the Leafy Green Marketing Agreement (LGMA) relative to its costs provides an approach to evaluating the cost-effectiveness of good agricultural practices that uses available data. A case example for lettuce is used to evaluate data requirements and provide a methodological example to determine the cost-effectiveness of the LGMA water quality provision. Both cost and field data on pathogen or indicator bacterial levels are difficult and expensive to obtain prospectively. Therefore, methods to use existing field and experimental data are required. Based on data from current literature and experimental studies, we calculate a cost-efficiency ratio that expresses the reduction in E. coli concentration per dollar expenditure on testing of irrigation water. With appropriate data, the same type of analysis can be extended to soil amendments and other practices and to evaluation of public benefits of practices used in production. Careful use of existing and experimental data can lead to evaluation of an expanded set of practices.

  10. 22 CFR Appendix A to Part 201 - Supplier's Certificate and Agreement With the Agency for International Development (AID 282)

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Supplier's Certificate and Agreement With the Agency for International Development (AID 282) A Appendix A to Part 201 Foreign Relations AGENCY FOR..., App. A Appendix A to Part 201—Supplier's Certificate and Agreement With the Agency for...

  11. Assessment of MSFCs Process for the Development and Activation of Space Act Agreements

    NASA Technical Reports Server (NTRS)

    Daugherty, Rachel A.

    2014-01-01

    A Space Act Agreement (SAA) is a contractual vehicle that NASA utilizes to form partnerships with non-NASA entities to stimulate cutting-edge innovation within the science and technology communities while concurrently supporting the NASA missions. SAAs are similar to traditional contracts in that they involve the commitment of Agency resources but allow more flexibility and are more cost effective to implement than traditional contracts. Consequently, the use of SAAs to develop partnerships has greatly increased over the past several years. To facilitate this influx of SAAs, Marshall Space Flight Center (MSFC) developed a process during a kaizen event to streamline and improve the quality of SAAs developed at the Center level. This study assessed the current SAA process to determine if improvements could be implemented to increase productivity, decrease time to activation, and improve the quality of deliverables. Using a combination of direct procedural observation, personnel interviews, and statistical analysis, elements of the process in need of remediation were identified and potential solutions developed. The findings focus primarily on the difficulties surrounding tracking and enforcing process adherence and communication issues among stakeholders. Potential solutions include utilizing customer relationship management (CRM) software to facilitate process coordination and co-locating or potentially merging the two separate organizations involved in SAA development and activation at MSFC.

  12. Paris Agreement on Climate Change: A Booster to Enable Sustainable Global Development and Beyond

    PubMed Central

    Bhore, Subhash Janardhan

    2016-01-01

    The global warming and its adverse effects on the atmosphere, the biosphere, the lithosphere, and the hydrosphere are obvious. Based on this fact, the international community is fully convinced that we need to fix the problem urgently for our survival, good health, and wellbeing. The aim of this article is to promote the awareness about the United Nations (UN) historic ‘Paris Agreement on Climate Change (PACC)’ which entered into-force on 4 November 2016. The expected impact of PACC on the global average temperature rise by 2100 as well as its role in enabling accomplishment of global sustainable development goals (SDGs) for the people and planet is also highlighted. PMID:27854248

  13. Development of a National Agreement on Human Papillomavirus Vaccination in Japan: An Infodemiology Study

    PubMed Central

    Yuji, Koichiro; Tsubokura, Masaharu; Ohsawa, Yukio; Kami, Masahiro

    2014-01-01

    Background A national agreement on human papillomavirus (HPV) vaccination was achieved relatively quickly in Japan as compared to the United States and India. Objective The objective was to identify the role of print and online media references, including references to celebrities or other informants, as factors potentially responsible for the relatively rapid national acceptance of HPV vaccination in Japan. Methods A method of text mining was performed to select keywords, representing the context of the target documents, from articles relevant to the promotion of HPV vaccination appearing in major Japanese newspapers and Web pages between January 2009 and July 2010. The selected keywords were classified as positive, negative, or neutral, and the transition of the frequency of their appearance was analyzed. Results The number of positive and neutral keywords appearing in newspaper articles increased sharply in early 2010 while the number of negative keywords remained low. The numbers of positive, neutral, and negative keywords appearing in Web pages increased gradually and did not significantly differ by category. Neutral keywords, such as “vaccine” and “prevention,” appeared more frequently in newspaper articles, whereas negative keywords, such as “infertility” and “side effect,” appeared more frequently in Web pages. The extraction of the positive keyword “signature campaign” suggests that vaccine beneficiaries cooperated with providers in promoting HPV vaccination. Conclusions The rapid development of a national agreement regarding HPV vaccination in Japan may be primarily attributed to the advocacy of vaccine beneficiaries, supported by advocacy by celebrities and positive reporting by print and online media. PMID:24834471

  14. Developing communications requirements for Agile Product Realization

    SciTech Connect

    Forsythe, C.; Ashby, M.R.

    1994-03-01

    Sandia National Laboratories has undertaken the Agile Product Realization for Innovative electroMEchanical Devices (A-PRIMED) pilot project to develop and implement technologies for agile design and manufacturing of electrochemical components. Emphasis on information-driven processes, concurrent engineering and multi-functional team communications makes computer-supported cooperative work critical to achieving significantly faster product development cycles. This report describes analyses conducted in developing communications requirements and a communications plan that addresses the unique communications demands of an agile enterprise.

  15. Framework Requirements for MDO Application Development

    NASA Technical Reports Server (NTRS)

    Salas, A. O.; Townsend, J. C.

    1999-01-01

    Frameworks or problem solving environments that support application development form an active area of research. The Multidisciplinary Optimization Branch at NASA Langley Research Center is investigating frameworks for supporting multidisciplinary analysis and optimization research. The Branch has generated a list of framework requirements, based on the experience gained from the Framework for Interdisciplinary Design Optimization project and the information acquired during a framework evaluation process. In this study, four existing frameworks are examined against these requirements. The results of this examination suggest several topics for further framework research.

  16. Audit of Administration of Cooperative Research and Development Agreements at DOE National Laboratories

    SciTech Connect

    1995-05-19

    DOE established policies to ensure that Cooperative Research and Development Agreements (CRADAS) enhance US competitiveness in the world economy, provide a reasonable return on resources invested, and enable successful commercialization of technologies developed. DOE`s Office of Technology Partnerships issued a General Guidance Memorandum to DOE operations offices establishing policy goals for technology transfer programs, including CRADAS. Our audit disclosed that efforts to manage CRADAs at three national laboratories did not fully achieve DOE`s policy goals outlined in the General Guidance Memorandum. Specifically, the audit showed that: (1) joint work statements did not always contain clearly defined information that allowed DOE to facilitate technology transfer or to evaluate CRADAs potential benefits; (2) CRADA statements of work did not always contain adequate documentation or address potential benefits; (3) the national laboratories reviewed did not have effective mechanisms for continuous self-appraisal or measures of overall program success; and (4) CRADA provisions did not exist to ensure an accurate evaluation of partner contributions.

  17. 75 FR 61503 - Cooperative Agreement With the World Health Organization for a Plan to Develop a Global...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-05

    ... a Plan to Develop a Global Integrated Food Safety Information Platform AGENCY: Food and Drug... Organization (WHO), Department of Food Safety and Zoonoses, to develop a plan for a global integrated food... for awarding a cooperative agreement to the WHO, Department of Food Safety and Zoonoses to develop...

  18. 75 FR 1814 - Solicitation for a Cooperative Agreement-Curriculum Development: Training for Correctional...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE... Justice. ACTION: Solicitation for a cooperative agreement. SUMMARY: The National Institute of Corrections... Correctional Industries Directors with the knowledge, skills and abilities needed to set...

  19. 78 FR 43923 - Solicitation for a Cooperative Agreement-Executive Excellence a Training and Development Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE.... Department of Justice. ACTION: Solicitation for a Cooperative Agreement. SUMMARY: The National Institute of... correctional or criminal justice chief executive officer, completed the current curriculum of...

  20. European Union’s Public Fishing Access Agreements in Developing Countries

    PubMed Central

    Le Manach, Frédéric; Chaboud, Christian; Copeland, Duncan; Cury, Philippe; Gascuel, Didier; Kleisner, Kristin M.; Standing, André; Sumaila, U. Rashid; Zeller, Dirk; Pauly, Daniel

    2013-01-01

    The imperative to increase seafood supply while dealing with its overfished local stocks has pushed the European Union (EU) and its Member States to fish in the Exclusive Economic Zones of other countries through various types of fishing agreements for decades. Although European public fishing agreements are commented on regularly and considered to be transparent, this is the first global and historical study on the fee regime that governs them. We find that the EU has subsidized these agreements at an average of 75% of their cost (financial contribution agreed upon in the agreements), while private European business interests paid the equivalent of 1.5% of the value of the fish that was eventually landed. This raises questions of fisheries benefit-sharing and resource-use equity that the EU has the potential to address during the nearly completed reform of its Common Fisheries Policy. PMID:24312191

  1. Distinct requirements for Wntless in habenular development

    PubMed Central

    Akitake, Courtney M.; Fortuno, Lea; Gamse, Joshua; Moens, Cecilia; Halpern, Marnie E.

    2015-01-01

    Secreted Wnt proteins play pivotal roles in development, including regulation of cell proliferation, differentiation, progenitor maintenance and tissue patterning. The transmembrane protein Wntless (Wls) is necessary for secretion of most Wnts and essential for effective Wnt signaling. During a mutagenesis screen to identify genes important for development of the habenular nuclei in the dorsal forebrain, we isolated a mutation in the sole wls gene of zebrafish and confirmed its identity with a second, independent allele. Early embryonic development appears normal in homozygous wls mutants, but they later lack the ventral habenular nuclei, form smaller dorsal habenulae and otic vesicles, have truncated jaw and fin cartilages and lack swim bladders. Activation of a reporter for β-catenin-dependent transcription is decreased in wls mutants, indicative of impaired signaling by the canonical Wnt pathway, and expression of Wnt-responsive genes is reduced in the dorsal diencephalon. Wnt signaling was previously implicated in patterning of the zebrafish brain and in the generation of left–right (L–R) differences between the bilaterally paired dorsal habenular nuclei. Outside of the epithalamic region, development of the brain is largely normal in wls mutants and, despite their reduced size, the dorsal habenulae retain L–R asymmetry. We find that homozygous wls mutants show a reduction in two cell populations that contribute to the presumptive dorsal habenulae. The results support distinct temporal requirements for Wls in habenular development and reveal a new role for Wnt signaling in the regulation of dorsal habenular progenitors. PMID:26116173

  2. Distinct requirements for Wntless in habenular development.

    PubMed

    Kuan, Yung-Shu; Roberson, Sara; Akitake, Courtney M; Fortuno, Lea; Gamse, Joshua; Moens, Cecilia; Halpern, Marnie E

    2015-10-15

    Secreted Wnt proteins play pivotal roles in development, including regulation of cell proliferation, differentiation, progenitor maintenance and tissue patterning. The transmembrane protein Wntless (Wls) is necessary for secretion of most Wnts and essential for effective Wnt signaling. During a mutagenesis screen to identify genes important for development of the habenular nuclei in the dorsal forebrain, we isolated a mutation in the sole wls gene of zebrafish and confirmed its identity with a second, independent allele. Early embryonic development appears normal in homozygous wls mutants, but they later lack the ventral habenular nuclei, form smaller dorsal habenulae and otic vesicles, have truncated jaw and fin cartilages and lack swim bladders. Activation of a reporter for β-catenin-dependent transcription is decreased in wls mutants, indicative of impaired signaling by the canonical Wnt pathway, and expression of Wnt-responsive genes is reduced in the dorsal diencephalon. Wnt signaling was previously implicated in patterning of the zebrafish brain and in the generation of left-right (L-R) differences between the bilaterally paired dorsal habenular nuclei. Outside of the epithalamic region, development of the brain is largely normal in wls mutants and, despite their reduced size, the dorsal habenulae retain L-R asymmetry. We find that homozygous wls mutants show a reduction in two cell populations that contribute to the presumptive dorsal habenulae. The results support distinct temporal requirements for Wls in habenular development and reveal a new role for Wnt signaling in the regulation of dorsal habenular progenitors.

  3. Mineral supply for sustainable development requires resource governance

    NASA Astrophysics Data System (ADS)

    Ali, Saleem H.; Giurco, Damien; Arndt, Nicholas; Nickless, Edmund; Brown, Graham; Demetriades, Alecos; Durrheim, Ray; Enriquez, Maria Amélia; Kinnaird, Judith; Littleboy, Anna; Meinert, Lawrence D.; Oberhänsli, Roland; Salem, Janet; Schodde, Richard; Schneider, Gabi; Vidal, Olivier; Yakovleva, Natalia

    2017-03-01

    Successful delivery of the United Nations sustainable development goals and implementation of the Paris Agreement requires technologies that utilize a wide range of minerals in vast quantities. Metal recycling and technological change will contribute to sustaining supply, but mining must continue and grow for the foreseeable future to ensure that such minerals remain available to industry. New links are needed between existing institutional frameworks to oversee responsible sourcing of minerals, trajectories for mineral exploration, environmental practices, and consumer awareness of the effects of consumption. Here we present, through analysis of a comprehensive set of data and demand forecasts, an interdisciplinary perspective on how best to ensure ecologically viable continuity of global mineral supply over the coming decades.

  4. 34 CFR 363.50 - What collaborative agreements must the State develop?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION THE STATE SUPPORTED EMPLOYMENT SERVICES PROGRAM What Post-Award Conditions Must Be Met by a State? § 363.50 What collaborative... 34 Education 2 2011-07-01 2010-07-01 true What collaborative agreements must the State...

  5. 76 FR 43726 - Solicitation for a Cooperative Agreement: Developing a Method for Conducting an Internal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE... Corrections, U.S. Department of Justice. ACTION: Solicitation for a Cooperative Agreement. SUMMARY: The... well who are recognized for their expertise and practical experience in working with justice-...

  6. 77 FR 39511 - Solicitation for a Cooperative Agreement: Development of a Guide for Correctional Agencies To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-03

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE... of Corrections, U.S. Department of Justice. ACTION: Solicitation for a cooperative agreement. SUMMARY... Bureau of Justice Statistics report (Mumola, C.J. NCJ 182335, 8/30/2000), of the nearly 2 million men...

  7. Federal Facility Agreement progress report

    SciTech Connect

    Not Available

    1993-10-01

    The (SRS) Federal Facility Agreement (FFA) was made effective by the US. Environmental Protection Agency Region IV (EPA) on August 16, 1993. To meet the reporting requirements in Section XXV of the Agreement, the FFA Progress Report was developed. The FFA Progress Report is the first of a series of quarterly progress reports to be prepared by the SRS. As such this report describes the information and action taken to September 30, 1993 on the SRS units identified for investigation and remediation in the Agreement. This includes; rubble pits, runoff basins, retention basin, seepage basin, burning pits, H-Area Tank 16, and spill areas.

  8. 78 FR 40191 - Solicitation for a Cooperative Agreement-Development and Pilot Training of a Curriculum for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-03

    ... of a Curriculum for Pretrial Justice System Stakeholders AGENCY: National Institute of Corrections, U... this cooperative agreement will involve the development and pilot of a training curriculum targeted... maintaining the pretrial justice system within their jurisdiction. This curriculum is intended to...

  9. 48 CFR 52.225-12 - Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... submission of offers. The offeror shall include the information and applicable supporting data required by... received a response to a previous request, the offeror shall include the information and supporting data in... conducted by sealed bidding; or (ii) May be accepted if revised during negotiations. (End of...

  10. 48 CFR 52.225-12 - Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... submission of offers. The offeror shall include the information and applicable supporting data required by... received a response to a previous request, the offeror shall include the information and supporting data in... conducted by sealed bidding; or (ii) May be accepted if revised during negotiations. (End of...

  11. 48 CFR 52.225-12 - Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... submission of offers. The offeror shall include the information and applicable supporting data required by... received a response to a previous request, the offeror shall include the information and supporting data in... conducted by sealed bidding; or (ii) May be accepted if revised during negotiations. (End of...

  12. Application Agreement and Integration Services

    NASA Technical Reports Server (NTRS)

    Driscoll, Kevin R.; Hall, Brendan; Schweiker, Kevin

    2013-01-01

    Application agreement and integration services are required by distributed, fault-tolerant, safety critical systems to assure required performance. An analysis of distributed and hierarchical agreement strategies are developed against the backdrop of observed agreement failures in fielded systems. The documented work was performed under NASA Task Order NNL10AB32T, Validation And Verification of Safety-Critical Integrated Distributed Systems Area 2. This document is intended to satisfy the requirements for deliverable 5.2.11 under Task 4.2.2.3. This report discusses the challenges of maintaining application agreement and integration services. A literature search is presented that documents previous work in the area of replica determinism. Sources of non-deterministic behavior are identified and examples are presented where system level agreement failed to be achieved. We then explore how TTEthernet services can be extended to supply some interesting application agreement frameworks. This document assumes that the reader is familiar with the TTEthernet protocol. The reader is advised to read the TTEthernet protocol standard [1] before reading this document. This document does not re-iterate the content of the standard.

  13. Audit of economic development grants and a cooperative agreement with East Tennessee not-for-profit organizations

    SciTech Connect

    1996-10-22

    As a result of the end of the Cold War, the Department of Energy (Department) has downsized many of its facilities. This may have a negative impact on many communities that were heavily dependent on Departmental operations for economic stability. To lessen the negative effects on these communities, the Department has encouraged the formation of community reuse organizations that are responsible for acting on behalf of the community to determine and sponsor initiatives to offset the consequences of the Department`s downsizing. One such initiative has been the award of economic development grants and cooperative agreements. The objective of the audit was to determine whether economic development grants and a cooperative agreement with East Tennessee not-for-profit organizations were achieving the Department`s intended purposes.

  14. Adapting veterinary infrastructures to meet the challenges of globalisation and the requirements of the World Trade Organization Agreement on Sanitary and Phytosanitary Measures.

    PubMed

    Thiermann, A

    2004-04-01

    To maximise the benefits of globalisation, countries and their stakeholders must become familiar with and adhere to the rights and obligations set out by the World Trade Organization under the Agreement on Sanitary and Phytosanitary Measures. Furthermore, for trade in animals and animal products, they must adhere to the standards, guidelines and recommendations established by the OIE (World organisation for animal health), which also encourages participation of countries in the standard-setting process. Only after implementing these requirements and strengthening veterinary infrastructures and surveillance and monitoring systems, will countries be able to fully benefit from the new international trade rules.

  15. 75 FR 56112 - Integrated Food Safety System Online Collaboration Development-Cooperative Agreement With the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... HUMAN SERVICES Food and Drug Administration Integrated Food Safety System Online Collaboration... information sharing in the development of an integrated food safety system, and the development and... House Food Safety Working Group Objectives to integrate the food safety system at all levels....

  16. Brandon Research, Inc. Orthopedic Implant Cooperative Research and Development Agreement (CRADA) Final Report

    SciTech Connect

    Freeman, W.R.

    1999-04-22

    The project was a joint research effort between the U. S. Department of Energy's (DOE) Kansas City Plant (KCP) and Brandon Research, Inc. to develop ways to improve implants used for orthopedic surgery for joint replacement. The primary product produced by this study is design information, which may be used to develop implants that will improve long-term fixation and durability in the host bone environment.

  17. 78 FR 71632 - Cooperative Research and Development Agreement (CRADA) Opportunity With the Department of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-29

    ... with a common data management system in the following Government operations (described in detail later... intended to serve as a data point for the standard under development for reusable electronic conveyance...). Submit electronic comments and other data with the subject line ``RECONS Notice of Intent'' to...

  18. HVDC control developments - addressing system requirements

    SciTech Connect

    Hauth, R.L.; Patel, H.S.; Piwko, R.J.

    1984-01-01

    This article describes typical high voltage direct current (HVDC) control systems and some of the new developments in the control area. HVDC control systems are showing their flexible characteristics as demonstrated, for example, by the new modulation, torsional damping, and alternating current voltage and reactive power controllers. Extensive studies are conducted to design and integrate such controllers into HVDC systems and to assure against any detrimental interactions within the total control system. 8 figures.

  19. Developing IVHM Requirements for Aerospace Systems

    NASA Technical Reports Server (NTRS)

    Rajamani, Ravi; Saxena, Abhinav; Kramer, Frank; Augustin, Mike; Schroeder, John B.; Goebel, Kai; Shao, Ginger; Roychoudhury, Indranil; Lin, Wei

    2013-01-01

    The term Integrated Vehicle Health Management (IVHM) describes a set of capabilities that enable sustainable and safe operation of components and subsystems within aerospace platforms. However, very little guidance exists for the systems engineering aspects of design with IVHM in mind. It is probably because of this that designers have to use knowledge picked up exclusively by experience rather than by established process. This motivated a group of leading IVHM practitioners within the aerospace industry under the aegis of SAE's HM-1 technical committee to author a document that hopes to give working engineers and program managers clear guidance on all the elements of IVHM that they need to consider before designing a system. This proposed recommended practice (ARP6883 [1]) will describe all the steps of requirements generation and management as it applies to IVHM systems, and demonstrate these with a "real-world" example related to designing a landing gear system. The team hopes that this paper and presentation will help start a dialog with the larger aerospace community and that the feedback can be used to improve the ARP and subsequently the practice of IVHM from a systems engineering point-of-view.

  20. IT roadmap requirements for research and development

    SciTech Connect

    Geyer, Leslie J; Kinkead, Susan F

    2010-01-01

    In 2009, members representing the programmatic community of the Laboratory presented a request to the Information Architecture Steering Committee (IASC) to form a committee within the Information Architecture Program (IAP) to review and consider the needs of researchers. In response, a Research and Development Subteam under the Infrastructure Team was created. Members included volunteer representatives of groups performing research and development throughout the Laboratory. This paper represents the product of this review. The R&D computing environment has languished while Los Alamos has been very compliance driven for the past few years under a set of directives that have eliminated our ability to innovate and to push the envelope of R&D computing. The appeal for outside collaborations is rapidly becoming tarnished, as colleagues from outside the NNSA environment view our restrictions as increasingly oppressive. We are losing the ability to conduct cutting-edge research and losing money to competitors who are able to quickly react and pursue program dollars while we are still creating compliant but less than useful computing solutions. Research programs depend on collaboration, employees, foreign nationals, and frequent travel, including travel to foreign countries. Solutions need to facilitate these activities and be based on the risk that the activities actually pose to the infrastructure and data at LANL. Furthermore, when problems are solved, it is essential that the solutions are evaluated for cost/benefit to the programs, that programmatic impact is well identified, and that solutions have sufficient long term resource for collaborations.

  1. Developing sorbent standards for spill response: Effects of the Oil Pollution Act of 1990 and the Free Trade Agreement

    NASA Astrophysics Data System (ADS)

    Schrader, E. L.; Westover, E. S.

    1993-09-01

    For the past five years the Millsaps Sorbent Laboratory has been actively engaged in developing standards for initial and long-term oil spill remedial technologies. As a voting member of the American Society of Testing Materials (ASTM) F-20 Committee, Canadian General Standards Board, and the US Coast Guard Sorbents Task Force, the laboratory has been engaged in developing useful, pragmatic protocols for various chemical and physical sorbent and filtration technologies driven by the deadlines imposed by the Oil Pollution Act of 1990 (OPA 90). The “open border” approach to certification of technologies and products promulgated by the US/Canadian Free Trade Agreement has placed the US users and producers of such products and systems in a unique and tenuous position. Canadian standards and goals are grandfathered into the United States under this agreement and products have official US government certification based on Canadian regulations. This situation is unfavorable to the US domestic environment and economy for several specific scenarios. Included in these scenarios are: abundant warmwater zones and inland waters of the US versus Canada, the basic chemical variation between Canadian and US crude oils, the different generally accepted remediation technologies in the US versus Canadian, and the technology validation procedures prior to purchase inherent to both countries.

  2. Agreement Execution Process Study: CRADAs and NF-WFO Agreements and the Speed of Business

    SciTech Connect

    Harrer, Bruce J.; Cejka, Cheryl L.; Macklin, Richard; Miksovic, Ann

    2011-02-01

    This report summarizes the findings of a study on the execution of Cooperative Research and Development Agreements (CRADAs) and Non-Federal Work for Others (NF-WFO) agreements across the U.S. Department of Energy (DOE) laboratory complex. The study provides quantitiative estimates of times required to negotiate and execute these agreements across the DOE complex. It identifies factors impacting on cycle times and describes best practicies used at various laboratories and site offices that reduce cycle times.

  3. Follow-On Cooperative Research and Development Agreement: MFIX to FLUENT Technology Transfer and Validation Studies Final Report

    SciTech Connect

    Madhava Syamlal; Guenther, Chris; O'Brien, Thomas J.; Benyahia, Sofiane; Shi, Shaoping

    2005-03-01

    This report summarizes the effort by NETL and Fluent on the Cooperative Research and Development Agreement No. 00-F039 signed in May 2000. The objective of the CRADA was to transfer technology from NETL's MFIX code into the commercial software FLUENT so as to increase the computational speed, accuracy, and utility of FLUENT. During the period of this CRADA MFIX was used to develop granular flow theories and used for simulating gas-solids chemical reactors. The FLUENT and MFIX predictions were compared with each other and with experimental data generated at NETL. The granular kinetic theory in FLUENT was improved as a result of this work, and a gas-solids reaction (ozone decomposition) was used as a test case for the gas-solids chemical reaction capability in FLUENT. Also, under a separate project, work has begun to transfer the coal combustion and gasification model in MFIX to FLUENT.

  4. Requirements Development for the NASA Advanced Engineering Environment (AEE)

    NASA Technical Reports Server (NTRS)

    Rogers, Eric; Hale, Joseph P.; Zook, Keith; Gowda, Sanjay; Salas, Andrea O.

    2003-01-01

    The requirements development process for the Advanced Engineering Environment (AEE) is presented. This environment has been developed to allow NASA to perform independent analysis and design of space transportation architectures and technologies. Given the highly collaborative and distributed nature of AEE, a variety of organizations are involved in the development, operations and management of the system. Furthermore, there are additional organizations involved representing external customers and stakeholders. Thorough coordination and effective communication is essential to translate desired expectations of the system into requirements. Functional, verifiable requirements for this (and indeed any) system are necessary to fulfill several roles. Requirements serve as a contractual tool, configuration management tool, and as an engineering tool, sometimes simultaneously. The role of requirements as an engineering tool is particularly important because a stable set of requirements for a system provides a common framework of system scope and characterization among team members. Furthermore, the requirements provide the basis for checking completion of system elements and form the basis for system verification. Requirements are at the core of systems engineering. The AEE Project has undertaken a thorough process to translate the desires and expectations of external customers and stakeholders into functional system-level requirements that are captured with sufficient rigor to allow development planning, resource allocation and system-level design, development, implementation and verification. These requirements are maintained in an integrated, relational database that provides traceability to governing Program requirements and also to verification methods and subsystem-level requirements.

  5. 14 CFR 152.111 - Application requirements: Airport development.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Application requirements: Airport... TRANSPORTATION (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Eligibility Requirements and Application Procedures § 152.111 Application requirements: Airport development. (a) An eligible sponsor that desires to...

  6. 14 CFR 152.111 - Application requirements: Airport development.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Application requirements: Airport... TRANSPORTATION (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Eligibility Requirements and Application Procedures § 152.111 Application requirements: Airport development. (a) An eligible sponsor that desires to...

  7. 24 CFR 585.402 - Grant agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 3 2011-04-01 2010-04-01 true Grant agreement. 585.402 Section 585.402 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... recipient will provide education and job training in accordance with the requirements of this part...

  8. JouleLabs Cooperative Research and Development Agreement: Cooperative Research and Development Final Report, CRADA Number CRD-08-00301

    SciTech Connect

    Bilello, D.

    2010-08-01

    The National Renewable Energy Laboratory (NREL) and Joule Labs Inc. (Joule Labs) will collaborate on creating a software platform for the development and distribution of renewable energy and energy efficiency analysis tools.

  9. Perceived Requirements of MIS Curriculum Implementation in Bilingual Developing Countries

    ERIC Educational Resources Information Center

    Kabeil, Magdy M.

    2005-01-01

    This paper addresses additional requirements associated with implementing a standard curriculum of Management Information Systems (MIS) in bilingual developing countries where both students and workplace users speak English as a second language. In such countries, MIS graduates are required to develop bilingual computer applications and to…

  10. Development of physiotherapy inherent requirement statements – an Australian experience

    PubMed Central

    2013-01-01

    Background The United Nations Convention on the Rights of People with Disabilities promotes equal rights of people with a disability in all aspects of their life including their education. In Australia, Disability Discrimination legislation underpins this Convention. It mandates that higher education providers must demonstrate that no discrimination has occurred and all reasonable accommodations have been considered and implemented, to facilitate access and inclusion for a student with a disability. The first step to meeting legislative requirements is to provide students with information on the inherent requirements of a course. This paper describes the steps which were taken to develop inherent requirement statements for a 4-year entry-level physiotherapy program at one Australian university. Case presentation Inherent requirement statements were developed using an existing framework, which was endorsed and mandated by the University. Items which described inherencies were extracted from Australian physiotherapy professional standards and statutory regulatory requirements, and units contained in the physiotherapy program. Data were integrated into the 8 prescribed domains: ethical behaviour, behavioural stability, legal, communication, cognition, sensory abilities, strength and mobility, and sustainable performance. Statements for each domain were developed using a 5-level framework (introductory statement, description of the inherent requirement, justification for inherency, characteristics of reasonable adjustments and exemplars) and reviewed by a University Review Panel. Refinement of statements continued until no further changes were required. Fifteen physiotherapy inherent requirement statements were developed. The eight domains identified in the existing framework, developed for Nursing, were relevant to the study of physiotherapy. Conclusions The inherent requirement statements developed in this study provide a transparent, defensible position on the

  11. Technology and development requirements for advanced coal conversion systems

    NASA Technical Reports Server (NTRS)

    1981-01-01

    A compendium of coal conversion process descriptions is presented. The SRS and MC data bases were utilized to provide information paticularly in the areas of existing process designs and process evaluations. Additional information requirements were established and arrangements were made to visit process developers, pilot plants, and process development units to obtain information that was not otherwise available. Plant designs, process descriptions and operating conditions, and performance characteristics were analyzed and requirements for further development identified and evaluated to determine the impact of these requirements on the process commercialization potential from the standpoint of economics and technical feasibility. A preliminary methodology was established for the comparative technical and economic assessment of advanced processes.

  12. Cooperative monitoring of regional security agreements

    SciTech Connect

    Pregenzer, A.L.; Vannoni, M.; Biringer, K.L.

    1996-11-01

    This paper argues that cooperative monitoring plays a critical role in the implementation of regional security agreements and confidence building measures. A framework for developing cooperative monitoring options is proposed and several possibilities for relating bilateral and regional monitoring systems to international monitoring systems are discussed. Three bilateral or regional agreements are analyzed briefly to illustrate different possibilities. These examples illustrate that the relationship of regional or bilateral arms control or security agreements to international agreements depends on a number of factors: the overlap of provisions between regional and international agreements; the degree of interest in a regional agreement among the international community; efficiency in implementing the agreement; and numerous political considerations. Given the importance of regional security to the international community, regions should be encouraged to develop their own infrastructure for implementing regional arms control and other security agreements. A regional infrastructure need not preclude participation in an international regime. On the contrary, establishing regional institutions for arms control and nonproliferation could result in more proactive participation of regional parties in developing solutions for regional and international problems, thereby strengthening existing and future international regimes. Possible first steps for strengthening regional infrastructures are identified and potential technical requirements are discussed.

  13. Development and analysis of SCR requirements tables for system scenarios

    NASA Technical Reports Server (NTRS)

    Callahan, John R.; Morrison, Jeffery L.

    1995-01-01

    We describe the use of scenarios to develop and refine requirement tables for parts of the Earth Observing System Data and Information System (EOSDIS). The National Aeronautics and Space Administration (NASA) is developing EOSDIS as part of its Mission-To-Planet-Earth (MTPE) project to accept instrument/platform observation requests from end-user scientists, schedule and perform requested observations of the Earth from space, collect and process the observed data, and distribute data to scientists and archives. Current requirements for the system are managed with tools that allow developers to trace the relationships between requirements and other development artifacts, including other requirements. In addition, the user community (e.g., earth and atmospheric scientists), in conjunction with NASA, has generated scenarios describing the actions of EOSDIS subsystems in response to user requests and other system activities. As part of a research effort in verification and validation techniques, this paper describes our efforts to develop requirements tables from these scenarios for the EOSDIS Core System (ECS). The tables specify event-driven mode transitions based on techniques developed by the Naval Research Lab's (NRL) Software Cost Reduction (SCR) project. The SCR approach has proven effective in specifying requirements for large systems in an unambiguous, terse format that enhance identification of incomplete and inconsistent requirements. We describe development of SCR tables from user scenarios and identify the strengths and weaknesses of our approach in contrast to the requirements tracing approach. We also evaluate the capabilities of both approach to respond to the volatility of requirements in large, complex systems.

  14. Ground Systems Development Environment (GSDE) interface requirements analysis

    NASA Technical Reports Server (NTRS)

    Church, Victor E.; Philips, John; Hartenstein, Ray; Bassman, Mitchell; Ruskin, Leslie; Perez-Davila, Alfredo

    1991-01-01

    A set of procedural and functional requirements are presented for the interface between software development environments and software integration and test systems used for space station ground systems software. The requirements focus on the need for centralized configuration management of software as it is transitioned from development to formal, target based testing. This concludes the GSDE Interface Requirements study. A summary is presented of findings concerning the interface itself, possible interface and prototyping directions for further study, and results of the investigation of the Cronus distributed applications environment.

  15. Advanced Extra-Vehicular Activity Pressure Garment Requirements Development

    NASA Technical Reports Server (NTRS)

    Ross, Amy; Aitchison, Lindsay; Rhodes, Richard

    2015-01-01

    The NASA Johnson Space Center advanced pressure garment technology development team is addressing requirements development for exploration missions. Lessons learned from the Z-2 high fidelity prototype development have reiterated that clear low-level requirements and verification methods reduce risk to the government, improve efficiency in pressure garment design efforts, and enable the government to be a smart buyer. The expectation is to provide requirements at the specification level that are validated so that their impact on pressure garment design is understood. Additionally, the team will provide defined verification protocols for the requirements. However, in reviewing exploration space suit high level requirements there are several gaps in the team's ability to define and verify related lower level requirements. This paper addresses the efforts in requirement areas such as mobility/fit/comfort and environmental protection (dust, radiation, plasma, secondary impacts) to determine the method by which the requirements can be defined and use of those methods for verification. Gaps exist at various stages. In some cases component level work is underway, but no system level effort has begun; in other cases no effort has been initiated to close the gap. Status of on-going efforts and potential approaches to open gaps are discussed.

  16. Section 508 Electronic Information Accessibility Requirements for Software Development

    NASA Technical Reports Server (NTRS)

    Ellis, Rebecca

    2014-01-01

    Section 508 Subpart B 1194.21 outlines requirements for operating system and software development in order to create a product that is accessible to users with various disabilities. This portion of Section 508 contains a variety of standards to enable those using assistive technology and with visual, hearing, cognitive and motor difficulties to access all information provided in software. The focus on requirements was limited to the Microsoft Windows® operating system as it is the predominant operating system used at this center. Compliance with this portion of the requirements can be obtained by integrating the requirements into the software development cycle early and by remediating issues in legacy software if possible. There are certain circumstances with software that may arise necessitating an exemption from these requirements, such as design or engineering software using dynamically changing graphics or numbers to convey information. These exceptions can be discussed with the Section 508 Coordinator and another method of accommodation used.

  17. Remote Sensing System Requirements Development: A Simulation-Based Approach

    NASA Technical Reports Server (NTRS)

    Zanoni, Vicki; Davis, Bruce; Ryan, Robert; Blonski, Slavomir; Gasser, Gerald

    2002-01-01

    Earth science research and application requirements for multispectral data have often been driven by currently available remote sensing technology. Few parametric studies exist that specify data required for certain applications. Consequently, data requirements are often defined based on the best data available or on what has worked successfully in the past. Since properites such as spatial resolution, swath width, spectral bands, signal-to-noise ratio (SNR), data quantization, and band-to-band registration drive sensor platform and spaceraft system architecture and cost, analysis of these criteria is important to objectively optimize system design. Remote sensing data requirements are also linked to calibration and characterization methods. Parameters such as spatial resolution, radiometric accuracy, and geopositional accuracy affect the complexity and cost of calibration methods. However, there are few studies that quantify the true accuracies required for specific problems. As calibration methods and standards are proposed, it is important that they be tied to well-known data requirements. The Application Research Toolbox (ART) developed at Stennis Space Center provides a simulation-based method for multispectral data requirements development. The ART produces simulated data sets from hyperspectral data through band synthesis. Parameters such as spectral band shape and width, SNR, data quantization, spatial resolution, and band-to-band registration can be varied to create many different simulated data products. Simulated data utility can then be assessed for different applications so that requirements can be better understood. This paper describes the ART and its applicability for rigorously deriving remote sensing data requirements.

  18. Structured interview for mild traumatic brain injury after military blast: inter-rater agreement and development of diagnostic algorithm.

    PubMed

    Walker, William C; Cifu, David X; Hudak, Anne M; Goldberg, Gary; Kunz, Richard D; Sima, Adam P

    2015-04-01

    The existing gold standard for diagnosing a suspected previous mild traumatic brain injury (mTBI) is clinical interview. But it is prone to bias, especially for parsing the physical versus psychological effects of traumatic combat events, and its inter-rater reliability is unknown. Several standardized TBI interview instruments have been developed for research use but have similar limitations. Therefore, we developed the Virginia Commonwealth University (VCU) retrospective concussion diagnostic interview, blast version (VCU rCDI-B), and undertook this cross-sectional study aiming to 1) measure agreement among clinicians' mTBI diagnosis ratings, 2) using clinician consensus develop a fully structured diagnostic algorithm, and 3) assess accuracy of this algorithm in a separate sample. Two samples (n = 66; n = 37) of individuals within 2 years of experiencing blast effects during military deployment underwent semistructured interview regarding their worst blast experience. Five highly trained TBI physicians independently reviewed and interpreted the interview content and gave blinded ratings of whether or not the experience was probably an mTBI. Paired inter-rater reliability was extremely variable, with kappa ranging from 0.194 to 0.825. In sample 1, the physician consensus prevalence of probable mTBI was 84%. Using these diagnosis ratings, an algorithm was developed and refined from the fully structured portion of the VCU rCDI-B. The final algorithm considered certain symptom patterns more specific for mTBI than others. For example, an isolated symptom of "saw stars" was deemed sufficient to indicate mTBI, whereas an isolated symptom of "dazed" was not. The accuracy of this algorithm, when applied against the actual physician consensus in sample 2, was almost perfect (correctly classified = 97%; Cohen's kappa = 0.91). In conclusion, we found that highly trained clinicians often disagree on historical blast-related mTBI determinations. A fully structured interview

  19. Requirement to Provide Estimates of Outcomes and To Track Progress for Proposed Grant and Cooperative Agreement Projects Frequently Asked Questions (FAQs)

    EPA Pesticide Factsheets

    The following FAQs were compiled to benefit prospective applicants seeking to apply for grants or cooperative agreements under the Pollution Prevention Division's Grant Programs (CFDA 66.708 and CFDA 66.717).

  20. Remote Sensing Requirements Development: A Simulation-Based Approach

    NASA Technical Reports Server (NTRS)

    Zanoni, Vicki; Davis, Bruce; Ryan, Robert; Gasser, Gerald; Blonski, Slawomir

    2002-01-01

    Earth science research and application requirements for multispectral data have often been driven by currently available remote sensing technology. Few parametric studies exist that specify data required for certain applications. Consequently, data requirements are often defined based on the best data available or on what has worked successfully in the past. Since properties such as spatial resolution, swath width, spectral bands, signal-to-noise ratio (SNR), data quantization and band-to-band registration drive sensor platform and spacecraft system architecture and cost, analysis of these criteria is important to optimize system design objectively. Remote sensing data requirements are also linked to calibration and characterization methods. Parameters such as spatial resolution, radiometric accuracy and geopositional accuracy affect the complexity and cost of calibration methods. However, few studies have quantified the true accuracies required for specific problems. As calibration methods and standards are proposed, it is important that they be tied to well-known data requirements. The Application Research Toolbox (ART) developed at the John C. Stennis Space Center provides a simulation-based method for multispectral data requirements development. The ART produces simulated datasets from hyperspectral data through band synthesis. Parameters such as spectral band shape and width, SNR, data quantization, spatial resolution and band-to-band registration can be varied to create many different simulated data products. Simulated data utility can then be assessed for different applications so that requirements can be better understood.

  1. Requirements Development for Interoperability Simulation Capability for Law Enforcement

    SciTech Connect

    Holter, Gregory M.

    2004-05-19

    The National Counterdrug Center (NCC) was initially authorized by Congress in FY 1999 appropriations to create a simulation-based counterdrug interoperability training capability. As the lead organization for Research and Analysis to support the NCC, the Pacific Northwest National Laboratory (PNNL) was responsible for developing the requirements for this interoperability simulation capability. These requirements were structured to address the hardware and software components of the system, as well as the deployment and use of the system. The original set of requirements was developed through a process of conducting a user-based survey of requirements for the simulation capability, coupled with an analysis of similar development efforts. The user-based approach ensured that existing concerns with respect to interoperability within the law enforcement community would be addressed. Law enforcement agencies within the designated pilot area of Cochise County, Arizona, were surveyed using interviews and ride-alongs during actual operations. The results of this survey were then accumulated, organized, and validated with the agencies to ensure the accuracy of the results. These requirements were then supplemented by adapting operational requirements from existing systems to ensure system reliability and operability. The NCC adopted a development approach providing incremental capability through the fielding of a phased series of progressively more capable versions of the system. This allowed for feedback from system users to be incorporated into subsequent revisions of the system requirements, and also allowed the addition of new elements as needed to adapt the system to broader geographic and geopolitical areas, including areas along the southwest and northwest U.S. borders. This paper addresses the processes used to develop and refine requirements for the NCC interoperability simulation capability, as well as the response of the law enforcement community to the use of

  2. Ground Systems Development Environment (GSDE) interface requirements and prototyping plan

    NASA Technical Reports Server (NTRS)

    Church, Victor E.; Philips, John; Bassman, Mitchell; Williams, C.

    1990-01-01

    This report describes the data collection and requirements analysis effort of the Ground System Development Environment (GSDE) Interface Requirements study. It identifies potential problems in the interfaces among applications and processors in the heterogeneous systems that comprises the GSDE. It describes possible strategies for addressing those problems. It also identifies areas for further research and prototyping to demonstrate the capabilities and feasibility of those strategies and defines a plan for building the necessary software prototypes.

  3. Cooperative monitoring of regional security agreements

    SciTech Connect

    Pregenzer, A.L.; Vannoni, M.; Biringer, K.L.

    1995-08-01

    This paper argues that cooperative monitoring plays a critical role in the implementation of regional security agreements and confidence building measures. A framework for developing cooperative monitoring options is proposed and several possibilities for relating bilateral and regional monitoring systems to international monitoring systems are discussed. Three bilateral or regional agreements are analyzed briefly to illustrate different possibilities: (1) the demilitarization of the Sinai region between Israel and Egypt in the 1970s; (2) the 1991 quadripartite agreement for monitoring nuclear facilities among Brazil, Argentina, The Argentine-Brazilian Agency for Accounting and Control of Nuclear Materials and the International Atomic Energy Agency; and (3) a bilateral Open Skies agreement between Hungary and Romania in 1991. These examples illustrate that the relationship of regional or bilateral arms control or security agreements to international agreements depends on a number of factors: the overlap of provisions between regional and international agreements; the degree of interest in a regional agreement among the international community; efficiency in implementing the agreement; and numerous political considerations.Given the importance of regional security to the international community, regions should be encouraged to develop their own infrastructure for implementing regional arms control and other security agreements. A regional infrastructure need not preclude participation in an international regime. On the contrary, establishing regional institutions for arms control and nonproliferation could result in more proactive participation of regional parties in developing solutions for regional and international problems, thereby strengthening existing and future international regimes. Possible first steps for strengthening regional infrastructures are identified and potential technical requirements are discussed.

  4. Development of flight experiment task requirements. Volume 1: Summary

    NASA Technical Reports Server (NTRS)

    Hatterick, G. R.

    1972-01-01

    A study was conducted to develop the means to identify skills required of scientist passengers on advanced missions related to the space shuttle and RAM programs. The scope of the study was defined to include only the activities of on-orbit personnel which are directly related to, or required by, on-orbit experimentation and scientific investigations conducted on or supported by the shuttle orbiter. A program summary is presented which provides a description of the methodology developed, an overview of the activities performed during the study, and the results obtained through application of the methodology.

  5. Canadian Seismic Agreement

    SciTech Connect

    Wetmiller, R.J.; Lyons, J.A.; Shannon, W.E.; Munro, P.S.; Thomas, J.T.; Andrew, M.D.; Lapointe, S.P.; Lamontagne, M.; Wong, C.; Anglin, F.M.; Adams, J.; Cajka, M.G.; McNeil, W.; Drysdale, J.A. )

    1992-05-01

    This is a progress report of work carried out under the terms of a research agreement entitled the Canadian Seismic Agreement'' between the US Nuclear Regulatory Commission (USNRC), the Canadian Commercial Corporation and the Geophysics Division of the Geological Survey of Canada (GD/GSC) during the period from July 01, 1989 to June 30, 1990. The Canadian Seismic Agreement'' supports generally the operation of various seismograph stations in eastern Canada and the collection and analysis of earthquake data for the purpose of mitigating seismic hazards in eastern Canada and the northeastern US. The specific activities carried out in this one-year period are summarized below under four headings; Eastern Canada Telemetred Network and local network developments, Datalab developments, strong-motion network developments and earthquake activity. During this period the first surface fault unequivocably determined to have accompanied a historic earthquake in eastern North America, occurred in northern Quebec.

  6. FFTF Authorization Agreement

    SciTech Connect

    DAUTEL, W.A.

    2000-09-25

    The purpose of the Authorization Agreement is to serve as a mechanism whereby the U.S. Department of Energy, Richland Operations Office (RL) and Fluor Hanford (FH) jointly clarify and agree to key conditions for conducting work safely and efficiently in the Fast Flux Test Facility (FFTF). Work must be accomplished in a manner that achieves high levels of quality while protecting the environment and the safety and health of workers and the public, and complying with applicable contractual and regulatory requirements. It is the intent of this Agreement to address those items of significant importance in establishing and supporting the FFTF Authorization Envelope, but this Agreement in no way alters the terms and conditions of the Project Hanford Management Contract (PHMC), Contract Number DE-AC06-96RL13200.

  7. Mining Agreements with Indian Tribes

    ERIC Educational Resources Information Center

    Luebben, Tom

    1976-01-01

    The article discusses aspects of negotiating agreements for exploration, development, and mining of hard minerals on Indian Reservations. The agreements discussed are typical of copper agreements, but the general points under discussion are applicable to most hard minerals except for uranium, coal, and oil which are substantially different.…

  8. Development of water requirement factors for biomass conversion pathway.

    PubMed

    Singh, Shikhar; Kumar, Amit

    2011-01-01

    Published data were used to develop an integrated spreadsheet-based model to estimate total water requirement for 12 biomass conversion pathways. The water requirement for crop production was attributed only to the grains in the estimates since agricultural residues are produced irrespective of their use for fuel or electricity. Corn stover- and wheat straw-based ethanol production pathways are water efficient, requiring only 0.3 l, whereas biopower production pathways (i.e. direct combustion and bio-oil production) require about 0.8-0.9 l of water per MJ. Wheat- and corn-based ethanol production pathways consume 77 and 108 l of water per MJ, respectively. Utilization of switchgrass for production of ethanol, biopower through the direct combustion, and pyrolysis consume 128, 187 and 229 l of water per MJ, respectively. Biodiesel production from canola seed consumes 124 l of water per MJ. Corn stover- and wheat straw-based conversion pathways are most water efficient.

  9. Supersonic HLFC: Potential benefits and technology development requirements

    NASA Technical Reports Server (NTRS)

    Neumann, Frank

    1992-01-01

    The viewgraphs and discussion of the potential benefits and technology development requirements of supersonic Hybrid Laminar Flow Control (HLFC) are reviewed. For the last three years, Boeing has performed studies on the application of laminar flow control to High Speed Civil Transport (HSCT) configurations. Large potential net benefits were identified for laminar flow control, even after accounting for the significant implementation penalties. However, the technical risks are high at this time, and an early, aggressive technology development program is required if laminar flow control (LFC) is to be incorporated in a year 2005 HSCT program. The benefits and required development effort are addressed. Of all the aerodynamic advances that are being considered for the HSCT, LFC has the largest potential for improving the supersonic lift drag ratio of a given configuration. The work accomplished to date, sponsored by NASA Langley, is summarized. This work includes studies on HLFC application to HSCT, cruise HLFC/low speed boundary layer control (BLC) compatibility, and impact of M 0.9 HLFC and high lift BLC. Requirements for production committments are listed. The need for a HSCT-HLFC Risk Reduction Program is addressed. Supersonic HLFC development planning and future applications are addressed. Laminar flow/high-lift integration is addressed.

  10. Prioritization Methodology for Development of Required Operational Capabilities

    DTIC Science & Technology

    2010-04-01

    Cours d’économie politique professé à l’université de Lausanne, 3 vol., 1896-7. 4 Pareto, V., (1935), The Mind and Society [Trattato Di Sociologia ...and Applications: A State-of-the- Art Survey, Springer-Verlag, New York. Prioritization Methodology for Development of Required Operational

  11. Nuclear thermal propulsion test facility requirements and development strategy

    NASA Technical Reports Server (NTRS)

    Allen, George C.; Warren, John; Clark, J. S.

    1991-01-01

    The Nuclear Thermal Propulsion (NTP) subpanel of the Space Nuclear Propulsion Test Facilities Panel evaluated facility requirements and strategies for nuclear thermal propulsion systems development. High pressure, solid core concepts were considered as the baseline for the evaluation, with low pressure concepts an alternative. The work of the NTP subpanel revealed that a wealth of facilities already exists to support NTP development, and that only a few new facilities must be constructed. Some modifications to existing facilities will be required. Present funding emphasis should be on long-lead-time items for the major new ground test facility complex and on facilities supporting nuclear fuel development, hot hydrogen flow test facilities, and low power critical facilities.

  12. Developing operational requirements for the design of law enforcement technologies

    NASA Astrophysics Data System (ADS)

    Overlin, Trudy K.; Marts, Donna J.

    1995-05-01

    The Idaho National Engineering Laboratory (INEL) was awarded a two-year project to design and develop an air bag restraint for use in law enforcement patrol vehicles. The work has successfully proven the concept and is in the final stages of prototype development. The end product will be the design and delivery of one prototype unit to the National Institute of Justice for evaluation. The INEL also assessed possible technologies that could be used to halt suspects in fleeing vehicles and safely put an end to high-speed pursuits. During the assessment of these technologies, a set of operational requirements were developed that were useful in determining the appropriateness of the technologies for the law enforcement application. This paper discusses the importance of operational requirements in their application to the technologies assessment conducted in the laboratory. The paper discusses the law enforcement and pursuit environment in terms of liability, safety of operation, social acceptance, and effectiveness of technology.

  13. Generic Safety Requirements for Developing Safe Insulin Pump Software

    PubMed Central

    Zhang, Yi; Jetley, Raoul; Jones, Paul L; Ray, Arnab

    2011-01-01

    Background The authors previously introduced a highly abstract generic insulin infusion pump (GIIP) model that identified common features and hazards shared by most insulin pumps on the market. The aim of this article is to extend our previous work on the GIIP model by articulating safety requirements that address the identified GIIP hazards. These safety requirements can be validated by manufacturers, and may ultimately serve as a safety reference for insulin pump software. Together, these two publications can serve as a basis for discussing insulin pump safety in the diabetes community. Methods In our previous work, we established a generic insulin pump architecture that abstracts functions common to many insulin pumps currently on the market and near-future pump designs. We then carried out a preliminary hazard analysis based on this architecture that included consultations with many domain experts. Further consultation with domain experts resulted in the safety requirements used in the modeling work presented in this article. Results Generic safety requirements for the GIIP model are presented, as appropriate, in parameterized format to accommodate clinical practices or specific insulin pump criteria important to safe device performance. Conclusions We believe that there is considerable value in having the diabetes, academic, and manufacturing communities consider and discuss these generic safety requirements. We hope that the communities will extend and revise them, make them more representative and comprehensive, experiment with them, and use them as a means for assessing the safety of insulin pump software designs. One potential use of these requirements is to integrate them into model-based engineering (MBE) software development methods. We believe, based on our experiences, that implementing safety requirements using MBE methods holds promise in reducing design/implementation flaws in insulin pump development and evolutionary processes, therefore improving

  14. Development of Airport Surface Required Navigation Performance (RNP)

    NASA Technical Reports Server (NTRS)

    Cassell, Rick; Smith, Alex; Hicok, Dan

    1999-01-01

    The U.S. and international aviation communities have adopted the Required Navigation Performance (RNP) process for defining aircraft performance when operating the en-route, approach and landing phases of flight. RNP consists primarily of the following key parameters - accuracy, integrity, continuity, and availability. The processes and analytical techniques employed to define en-route, approach and landing RNP have been applied in the development of RNP for the airport surface. To validate the proposed RNP requirements several methods were used. Operational and flight demonstration data were analyzed for conformance with proposed requirements, as were several aircraft flight simulation studies. The pilot failure risk component was analyzed through several hypothetical scenarios. Additional simulator studies are recommended to better quantify crew reactions to failures as well as additional simulator and field testing to validate achieved accuracy performance, This research was performed in support of the NASA Low Visibility Landing and Surface Operations Programs.

  15. HLLV avionics requirements study and electronic filing system database development

    NASA Technical Reports Server (NTRS)

    1994-01-01

    This final report provides a summary of achievements and activities performed under Contract NAS8-39215. The contract's objective was to explore a new way of delivering, storing, accessing, and archiving study products and information and to define top level system requirements for Heavy Lift Launch Vehicle (HLLV) avionics that incorporate Vehicle Health Management (VHM). This report includes technical objectives, methods, assumptions, recommendations, sample data, and issues as specified by DPD No. 772, DR-3. The report is organized into two major subsections, one specific to each of the two tasks defined in the Statement of Work: the Index Database Task and the HLLV Avionics Requirements Task. The Index Database Task resulted in the selection and modification of a commercial database software tool to contain the data developed during the HLLV Avionics Requirements Task. All summary information is addressed within each task's section.

  16. The actual development of European aviation safety requirements in aviation medicine: prospects of future EASA requirements.

    PubMed

    Siedenburg, J

    2009-04-01

    Common Rules for Aviation Safety had been developed under the aegis of the Joint Aviation Authorities in the 1990s. In 2002 the Basic Regulation 1592/2002 was the founding document of a new entity, the European Aviation Safety Agency. Areas of activity were Certification and Maintenance of aircraft. On 18 March the new Basic Regulation 216/2008, repealing the original Basic Regulation was published and applicable from 08 April on. The included Essential Requirements extended the competencies of EASA inter alia to Pilot Licensing and Flight Operations. The future aeromedical requirements will be included as Annex II in another Implementing Regulation on Personnel Licensing. The detailed provisions will be published as guidance material. The proposals for these provisions have been published on 05 June 2008 as NPA 2008- 17c. After public consultation, processing of comments and final adoption the new proposals may be applicable form the second half of 2009 on. A transition period of four year will apply. Whereas the provisions are based on Joint Aviation Requirement-Flight Crew Licensing (JAR-FCL) 3, a new Light Aircraft Pilot Licence (LAPL) project and the details of the associated medical certification regarding general practitioners will be something new in aviation medicine. This paper consists of 6 sections. The introduction outlines the idea of international aviation safety. The second section describes the development of the Joint Aviation Authorities (JAA), the first step to common rules for aviation safety in Europe. The third section encompasses a major change as next step: the foundation of the European Aviation Safety Agency (EASA) and the development of its rules. In the following section provides an outline of the new medical requirements. Section five emphasizes the new concept of a Leisure Pilot Licence. The last section gives an outlook on ongoing rulemaking activities and the opportunities of the public to participate in them.

  17. The actual development of European Aviation Safety Requirements in Aviation Medicine: Prospects of Future EASA Requirements

    PubMed Central

    Siedenburg, J

    2009-01-01

    Common Rules for Aviation Safety had been developed under the aegis of the Joint Aviation Authorities in the 1990ies. In 2002 the Basic Regulation 1592/2002 was the founding document of a new entity, the European Aviation Safety Agency. Areas of activity were Certification and Maintenance of aircraft. On 18 March the new Basic Regulation 216/2008, repealing the original Basic Regulation was published and applicable from 08 April on. The included Essential Requirements extended the competencies of EASA inter alia to Pilot Licensing and Flight Operations. The future aeromedical requirements will be included as Annex II in another Implementing Regulation on Personnel Licensing. The detailed provisions will be published as guidance material. The proposals for these provisions have been published on 05 June 2008 as NPA 2008- 17c. After public consultation, processing of comments and final adoption the new proposals may be applicable form the second half of 2009 on. A transition period of four year will apply. Whereas the provisions are based on Joint Awiation Requirement - Flight Crew Licensing (JAR-FCL) 3, a new Light Aircraft Pilot Licence (LAPL) project and the details of the associated medical certification regarding general practitioners will be something new in aviation medicine. This paper consists of 6 sections. The introduction outlines the idea of international aviation safety. The second section describes the development of the Joint Aviation Authorities (JAA), the first step to common rules for aviation safety in Europe. The third section encompasses a major change as next step: the foundation of the European Aviation Safety Agency (EASA) and the development of its rules. In the following section provides an outline of the new medical requirements. Section five emphasizes the new concept of a Leisure Pilot Licence. The last section gives an outlook on ongoing rulemaking activities and the opportunities of the public to participate in them. PMID:19561781

  18. Developing Tools and Technologies to Meet MSR Planetary Protection Requirements

    NASA Technical Reports Server (NTRS)

    Lin, Ying

    2013-01-01

    This paper describes the tools and technologies that need to be developed for a Caching Rover mission in order to meet the overall Planetary Protection requirements for future Mars Sample Return (MSR) campaign. This is the result of an eight-month study sponsored by the Mars Exploration Program Office. The goal of this study is to provide a future MSR project with a focused technology development plan for achieving the necessary planetary protection and sample integrity capabilities for a Mars Caching Rover mission.

  19. Mask substrate requirements and development for extreme ultraviolet lithography (EUVL)

    SciTech Connect

    Hector, S D; Shell, M; Taylor, J S; Tong, W M

    1999-09-28

    The mask is deemed one of the areas that require significant research and development in EUVL. Silicon wafers will be used for mask substrates for an alpha-class EUVL exposure tool due to their low-defect levels and high quality surface finish. However, silicon has a large coefficient of thermal expansion that leads to unacceptable image distortion due to absorption of EUV light. A low thermal expansion glass or glass-ceramic is likely to be required in order to meet error budgets for the 70nm node and beyond. Since EUVL masks are used in reflection, they are coated with multilayers prior to patterning. Surface imperfections, such as polishing marks, particles, scratches, or digs, are potential nucleation sites for defects in the multilayer coating, which could result in the printed defects. Therefore we are accelerating developments in the defect reduction and surface finishing of low thermal expansion mask substrates in order to understand long-term issues in controlling printable defects, and to establish the infrastructure for supplying masks. In this paper, we explain the technical requirements for EUVL mask substrates and describe our efforts in establishing a SEMI standard for EUVL masks. We will also report on the early progress of our suppliers in producing low thermal-expansion mask substrates for our development activities.

  20. 2 CFR 1401.220 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Cooperative agreement. 1401.220 Section 1401....220 Cooperative agreement. Cooperative agreement means an award of financial assistance that... include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  1. 2 CFR 182.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Cooperative agreement. 182.620 Section 182... § 182.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  2. Safety and regulatory requirements and challenge for CNS drug development.

    PubMed

    Gad, Shayne C

    2014-01-01

    As our recognition and understanding of diseases and disorders of the central nervous system (CNS) become more insightful, and society's concerns for the safety, efficacy, and use of such drugs become more acute, the regulatory requirements and expectations around assessing potential safety of the drug have continued to become more complex. Currently, these concerns and requirements are addressed in a time phased manner, attempting to match the advance of spending rate on assessing safety issues in alignment with advancing the moiety through development of the therapeutics. This article seeks to communicate all the critical but frequently overlooked aspects of current and pending regulatory requirements including the lesser known parts associated with impurities, active metabolites, and distribution of active components to (and subsequent clearance from) the population brain. While there are some exciting developments in treating CNS diseases with stem cells and some protein based therapies (Aboody et al., 2011), drugs meant to favorably effect, prevent, or cure a disease process within the central nervous system (CNS) are primarily small molecule and must meet a number of regulatory and scientifically mandated criteria to establish that their safety in clinical use is acceptable. This is initially done in in vivo animals or in in vitro preparations. The starting place for such nonclinical safety assessment requires some fundamental assumptions about the potential therapeutic (Ball et al., 2007; Gad, 2009; ICH S6, 2004; ICH M3 (R2), 2008). The first assumption is that the primary intended route of therapeutic administration is oral, as is indeed the case for the vast majority of both current and for most potential new drugs. Most aspects of nonclinical safety assessment do not depend on route, and we will consider the situations where the use of other routes influences requirements for nonclinical safety assessment, and why. A second general case assumption in the

  3. Basic Requirements for Systems Software Research and Development

    NASA Technical Reports Server (NTRS)

    Kuszmaul, Chris; Nitzberg, Bill

    1996-01-01

    Our success over the past ten years evaluating and developing advanced computing technologies has been due to a simple research and development (R/D) model. Our model has three phases: (a) evaluating the state-of-the-art, (b) identifying problems and creating innovations, and (c) developing solutions, improving the state- of-the-art. This cycle has four basic requirements: a large production testbed with real users, a diverse collection of state-of-the-art hardware, facilities for evalua- tion of emerging technologies and development of innovations, and control over system management on these testbeds. Future research will be irrelevant and future products will not work if any of these requirements is eliminated. In order to retain our effectiveness, the numerical aerospace simulator (NAS) must replace out-of-date production testbeds in as timely a fashion as possible, and cannot afford to ignore innovative designs such as new distributed shared memory machines, clustered commodity-based computers, and multi-threaded architectures.

  4. Unique spatiotemporal requirements for intraflagellar transport genes during forebrain development

    PubMed Central

    Chang, Ching-Fang; Cionni, Megan; Brugmann, Samantha A.

    2017-01-01

    Primary cilia are organelles extended from virtually all cells and are required for the proper regulation of a number of canonical developmental pathways. The role in cortical development of proteins important for ciliary form and function is a relatively understudied area. Here we have taken a genetic approach to define the role in forebrain development of three intraflagellar transport proteins known to be important for primary cilia function. We have genetically ablated Kif3a, Ift88, and Ttc21b in a series of specific spatiotemporal domains. The resulting phenotypes allow us to draw several conclusions. First, we conclude that the Ttc21b cortical phenotype is not due to the activity of Ttc21b within the brain itself. Secondly, some of the most striking phenotypes are from ablations in the neural crest cells and the adjacent surface ectoderm indicating that cilia transduce critical tissue—tissue interactions in the developing embryonic head. Finally, we note striking differences in phenotypes from ablations only one embryonic day apart, indicating very discrete spatiotemporal requirements for these three genes in cortical development. PMID:28291836

  5. Requirements and Techniques for Developing and Measuring Simulant Materials

    NASA Technical Reports Server (NTRS)

    Rickman, Doug; Owens, Charles; Howard, Rick

    2006-01-01

    The 1989 workshop report entitled Workshop on Production and Uses of Simulated Lunar Materials and the Lunar Regolith Simulant Materials: Recommendations for Standardization, Production, and Usage, NASA Technical Publication identify and reinforced a need for a set of standards and requirements for the production and usage of the lunar simulant materials. As NASA need prepares to return to the moon, a set of requirements have been developed for simulant materials and methods to produce and measure those simulants have been defined. Addressed in the requirements document are: 1) a method for evaluating the quality of any simulant of a regolith, 2) the minimum Characteristics for simulants of lunar regolith, and 3) a method to produce lunar regolith simulants needed for NASA's exploration mission. A method to evaluate new and current simulants has also been rigorously defined through the mathematics of Figures of Merit (FoM), a concept new to simulant development. A single FoM is conceptually an algorithm defining a single characteristic of a simulant and provides a clear comparison of that characteristic for both the simulant and a reference material. Included as an intrinsic part of the algorithm is a minimum acceptable performance for the characteristic of interest. The algorithms for the FoM for Standard Lunar Regolith Simulants are also explicitly keyed to a recommended method to make lunar simulants.

  6. PTBP1 is required for embryonic development before gastrulation.

    PubMed

    Suckale, Jakob; Wendling, Olivia; Masjkur, Jimmy; Jäger, Melanie; Münster, Carla; Anastassiadis, Konstantinos; Stewart, A Francis; Solimena, Michele

    2011-02-17

    Polypyrimidine-tract binding protein 1 (PTBP1) is an important cellular regulator of messenger RNAs influencing the alternative splicing profile of a cell as well as its mRNA stability, location and translation. In addition, it is diverted by some viruses to facilitate their replication. Here, we used a novel PTBP1 knockout mouse to analyse the tissue expression pattern of PTBP1 as well as the effect of its complete removal during development. We found evidence of strong PTBP1 expression in embryonic stem cells and throughout embryonic development, especially in the developing brain and spinal cord, the olfactory and auditory systems, the heart, the liver, the kidney, the brown fat and cartilage primordia. This widespread distribution points towards a role of PTBP1 during embryonic development. Homozygous offspring, identified by PCR and immunofluorescence, were able to implant but were arrested or retarded in growth. At day 7.5 of embryonic development (E7.5) the null mutants were about 5x smaller than the control littermates and the gap in body size widened with time. At mid-gestation, all homozygous embryos were resorbed/degraded. No homozygous mice were genotyped at E12 and the age of weaning. Embryos lacking PTBP1 did not display differentiation into the 3 germ layers and cavitation of the epiblast, which are hallmarks of gastrulation. In addition, homozygous mutants displayed malformed ectoplacental cones and yolk sacs, both early supportive structure of the embryo proper. We conclude that PTBP1 is not required for the earliest isovolumetric divisions and differentiation steps of the zygote up to the formation of the blastocyst. However, further post-implantation development requires PTBP1 and stalls in homozygous null animals with a phenotype of dramatically reduced size and aberration in embryonic and extra-embryonic structures.

  7. PTBP1 Is Required for Embryonic Development before Gastrulation

    PubMed Central

    Suckale, Jakob; Wendling, Olivia; Masjkur, Jimmy; Jäger, Melanie; Münster, Carla; Anastassiadis, Konstantinos; Stewart, A. Francis; Solimena, Michele

    2011-01-01

    Polypyrimidine-tract binding protein 1 (PTBP1) is an important cellular regulator of messenger RNAs influencing the alternative splicing profile of a cell as well as its mRNA stability, location and translation. In addition, it is diverted by some viruses to facilitate their replication. Here, we used a novel PTBP1 knockout mouse to analyse the tissue expression pattern of PTBP1 as well as the effect of its complete removal during development. We found evidence of strong PTBP1 expression in embryonic stem cells and throughout embryonic development, especially in the developing brain and spinal cord, the olfactory and auditory systems, the heart, the liver, the kidney, the brown fat and cartilage primordia. This widespread distribution points towards a role of PTBP1 during embryonic development. Homozygous offspring, identified by PCR and immunofluorescence, were able to implant but were arrested or retarded in growth. At day 7.5 of embryonic development (E7.5) the null mutants were about 5x smaller than the control littermates and the gap in body size widened with time. At mid-gestation, all homozygous embryos were resorbed/degraded. No homozygous mice were genotyped at E12 and the age of weaning. Embryos lacking PTBP1 did not display differentiation into the 3 germ layers and cavitation of the epiblast, which are hallmarks of gastrulation. In addition, homozygous mutants displayed malformed ectoplacental cones and yolk sacs, both early supportive structure of the embryo proper. We conclude that PTBP1 is not required for the earliest isovolumetric divisions and differentiation steps of the zygote up to the formation of the blastocyst. However, further post-implantation development requires PTBP1 and stalls in homozygous null animals with a phenotype of dramatically reduced size and aberration in embryonic and extra-embryonic structures. PMID:21423341

  8. 2 CFR 1401.220 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Cooperative agreement. 1401.220 Section 1401... INTERIOR REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1401.220 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  9. 2 CFR 182.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Cooperative agreement. 182.620 Section 182... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 182.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  10. 2 CFR 182.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Cooperative agreement. 182.620 Section 182... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 182.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  11. 2 CFR 1401.220 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Cooperative agreement. 1401.220 Section 1401... INTERIOR REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1401.220 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  12. 2 CFR 1401.220 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Cooperative agreement. 1401.220 Section 1401... INTERIOR REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1401.220 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  13. Ground Systems Development Environment (GSDE) interface requirements analysis: Operations scenarios

    NASA Technical Reports Server (NTRS)

    Church, Victor E.; Phillips, John

    1991-01-01

    This report is a preliminary assessment of the functional and data interface requirements to the link between the GSDE GS/SPF (Amdahl) and the Space Station Control Center (SSCC) and Space Station Training Facility (SSTF) Integration, Verification, and Test Environments (IVTE's). These interfaces will be involved in ground software development of both the control center and the simulation and training systems. Our understanding of the configuration management (CM) interface and the expected functional characteristics of the Amdahl-IVTE interface is described. A set of assumptions and questions that need to be considered and resolved in order to complete the interface functional and data requirements definitions are presented. A listing of information items defined to describe software configuration items in the GSDE CM system is included. It also includes listings of standard reports of CM information and of CM-related tools in the GSDE.

  14. Countries renew rescue agreement

    NASA Astrophysics Data System (ADS)

    Bush, Susan M.

    To insure long-term continuity for the international satellite search and rescue system, COSPAS/SARSAT, an intergovernmental agreement binding the four sponsoring nations to cooperate was signed July 1 in Paris. According to Russell Vollmers of the National Oceanic and Atmospheric Administration, the agreement is binding for 15 years, with an automatic extension.The system marked the fifth anniversary of its first rescue last year, when on September 10, 1982, three persons were rescued. Begun in the 1970s by NASA as an experiment, COSPAS/SARSAT (a Russian-English acronym) is now a cooperative project among the United States, Canada, France, and the Soviet Union. Its goal is to reduce the time required to rescue air and maritime distress victims and also to locate victims who otherwise may not be found, thus using the satellite system as a life-saving device.

  15. Differential requirements for survivin in hematopoietic cell development.

    PubMed

    Gurbuxani, Sandeep; Xu, Yanfei; Keerthivasan, Ganesan; Wickrema, Amittha; Crispino, John D

    2005-08-09

    Although erythroid cells and megakaryocytes arise from a common progenitor, their terminal maturation follows very different paths; erythroid cells undergo cell-cycle exit and enucleation, whereas megakaryocytes continue to progress through the cell cycle but skip late stages of mitosis to become polyploid cells. In our efforts to identify genes that participate in this process, we discovered that survivin, a member of the inhibitor of apoptosis family that also has an essential role in cytokinesis, is differentially expressed during erythroid versus megakaryocyte development. Erythroid cells express survivin throughout their maturation, whereas megakaryocytes express approximately 4-fold lower levels of survivin mRNA and no detectable protein. To investigate the role of survivin in these lineages, we overexpressed or knocked down survivin from mouse bone marrow cells and then examined erythroid and megakaryocyte development. These studies revealed that overexpression of survivin antagonized megakaryocyte growth, maturation, and polyploidization but had no effect on erythroid development. This block in polyploidization was accompanied by increased expression of p21 and decreased expression of megakaryocyte genes such as von Willebrand factor and beta(1)-tubulin. In contrast, a reduction in survivin expression interfered with the formation of erythroid cells but not megakaryocytes. Last, consistent with the requirement for survivin in the survival of proliferating cells, survivin-deficient hematopoietic progenitors failed to give rise to either erythroid or megakaryocytic colonies. Together, these studies show that whereas survivin expression is essential for megakaryocyte and erythroid progenitors, its down-regulation is required for terminal differentiation of megakaryocytes.

  16. Uniform administrative requirements for grants and agreements with institutions of higher education, hospitals and other non-profit organizations--OMB. Final revision to OMB circular A-110.

    PubMed

    1993-11-29

    Office of Management and Budget (OMB) Circular A-110 provides standards for obtaining consistency and uniformity among Federal agencies in the administration of grants and agreements with institutions of higher education, hospitals, and other non-profit organizations. OMB issued Circular A-110 in 1976 and, except for a minor revision in February 1987, the Circular contains its original provisions. To update the Circular, OMB established an interagency task force to review the Circular. The task force solicited suggestions for changes to the Circular from university groups, non-profit organizations and other interested parties and compared, for consistency, the provisions of similar provisions applied to State and local governments. The revised Circular reflects the results of these efforts.

  17. Software requirements: Guidance and control software development specification

    NASA Technical Reports Server (NTRS)

    Withers, B. Edward; Rich, Don C.; Lowman, Douglas S.; Buckland, R. C.

    1990-01-01

    The software requirements for an implementation of Guidance and Control Software (GCS) are specified. The purpose of the GCS is to provide guidance and engine control to a planetary landing vehicle during its terminal descent onto a planetary surface and to communicate sensory information about that vehicle and its descent to some receiving device. The specification was developed using the structured analysis for real time system specification methodology by Hatley and Pirbhai and was based on a simulation program used to study the probability of success of the 1976 Viking Lander missions to Mars. Three versions of GCS are being generated for use in software error studies.

  18. Advanced Environmental Monitoring and Control Program: Technology Development Requirements

    NASA Technical Reports Server (NTRS)

    Jan, Darrell (Editor); Seshan, Panchalam (Editor); Ganapathi, Gani (Editor); Schmidt, Gregory (Editor); Doarn, Charles (Editor)

    1996-01-01

    Human missions in space, from the International Space Station on towards potential human exploration of the moon, Mars and beyond into the solar system, will require advanced systems to maintain an environment that supports human life. These systems will have to recycle air and water for many months or years at a time, and avoid harmful chemical or microbial contamination. NASA's Advanced Environmental Monitoring and Control program has the mission of providing future spacecraft with advanced, integrated networks of microminiaturized sensors to accurately determine and control the physical, chemical and biological environment of the crew living areas. This document sets out the current state of knowledge for requirements for monitoring the crew environment, based on (1) crew health, and (2) life support monitoring systems. Both areas are updated continuously through research and space mission experience. The technologies developed must meet the needs of future life support systems and of crew health monitoring. These technologies must be inexpensive and lightweight, and use few resources. Using these requirements to continue to push the state of the art in miniaturized sensor and control systems will produce revolutionary technologies to enable detailed knowledge of the crew environment.

  19. Manned remote work station development article. Volume 1, book 1: Flight article requirements. Appendix A: Mission requirements

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The requirements for several configurations of flight articles are presented. These requirements provide the basis to design manned remote work station development test articles and establish tests and simulation objectives for the resolution of development issues. Mission system and subsystem requirements for four MRWS configurations included: open cherry picker; closed cherry picker; crane turret; and free flyer.

  20. Development of photovoltaic array and module safety requirements

    NASA Technical Reports Server (NTRS)

    1982-01-01

    Safety requirements for photovoltaic module and panel designs and configurations likely to be used in residential, intermediate, and large-scale applications were identified and developed. The National Electrical Code and Building Codes were reviewed with respect to present provisions which may be considered to affect the design of photovoltaic modules. Limited testing, primarily in the roof fire resistance field was conducted. Additional studies and further investigations led to the development of a proposed standard for safety for flat-plate photovoltaic modules and panels. Additional work covered the initial investigation of conceptual approaches and temporary deployment, for concept verification purposes, of a differential dc ground-fault detection circuit suitable as a part of a photovoltaic array safety system.

  1. A new market risk model for cogeneration project financing---combined heat and power development without a power purchase agreement

    NASA Astrophysics Data System (ADS)

    Lockwood, Timothy A.

    Federal legislative changes in 2006 no longer entitle cogeneration project financings by law to receive the benefit of a power purchase agreement underwritten by an investment-grade investor-owned utility. Consequently, this research explored the need for a new market-risk model for future cogeneration and combined heat and power (CHP) project financing. CHP project investment represents a potentially enormous energy efficiency benefit through its application by reducing fossil fuel use up to 55% when compared to traditional energy generation, and concurrently eliminates constituent air emissions up to 50%, including global warming gases. As a supplemental approach to a comprehensive technical analysis, a quantitative multivariate modeling was also used to test the statistical validity and reliability of host facility energy demand and CHP supply ratios in predicting the economic performance of CHP project financing. The resulting analytical models, although not statistically reliable at this time, suggest a radically simplified CHP design method for future profitable CHP investments using four easily attainable energy ratios. This design method shows that financially successful CHP adoption occurs when the average system heat-to-power-ratio supply is less than or equal to the average host-convertible-energy-ratio, and when the average nominally-rated capacity is less than average host facility-load-factor demands. New CHP investments can play a role in solving the world-wide problem of accommodating growing energy demand while preserving our precious and irreplaceable air quality for future generations.

  2. Medicare and Medicaid programs; changes in provider and supplier enrollment, ordering and referring, and documentation requirements; and changes in provider agreements. Interim final rule with comment period.

    PubMed

    2010-05-05

    This interim final rule with comment period implements several provisions set forth in the Patient Protection and Affordable Care Act (Affordable Care Act). It implements the provision which requires all providers of medical or other items or services and suppliers that qualify for a National Provider Identifier (NPI) to include their NPI on all applications to enroll in the Medicare and Medicaid programs and on all claims for payment submitted under the Medicare and Medicaid programs. This interim final rule with comment period also requires physicians and eligible professionals to order and refer covered items and services for Medicare beneficiaries to be enrolled in Medicare. In addition, it adds requirements for providers, physicians, and other suppliers participating in the Medicare program to provide documentation on referrals to programs at high risk of waste and abuse, to include durable medical equipment, prosthetics, orthotics and supplies (DMEPOS), home health services, and other items or services specified by the Secretary.

  3. Medicare and Medicaid programs; changes in provider and supplier enrollment, ordering and referring, and documentation requirements; and changes in provider agreements. Final rule.

    PubMed

    2012-04-27

    This final rule finalizes several provisions of the Affordable Care Act implemented in the May 5, 2010 interim final rule with comment period. It requires all providers of medical or other items or services and suppliers that qualify for a National Provider Identifier (NPI) to include their NPI on all applications to enroll in the Medicare and Medicaid programs and on all claims for payment submitted under the Medicare and Medicaid programs. In addition, it requires physicians and other professionals who are permitted to order and certify covered items and services for Medicare beneficiaries to be enrolled in Medicare. Finally, it mandates document retention and provision requirements on providers and supplier that order and certify items and services for Medicare beneficiaries.

  4. Critical Requirement of GABPα for Normal T Cell Development*

    PubMed Central

    Yu, Shuyang; Zhao, Dong-Mei; Jothi, Raja; Xue, Hai-Hui

    2010-01-01

    GA binding protein (GABP) consists of GABPα and GABPβ subunits. GABPα is a member of Ets family transcription factors and binds DNA via its conserved Ets domain, whereas GABPβ does not bind DNA but possesses transactivation activity. In T cells, GABP has been demonstrated to regulate the gene expression of interleukin-7 receptor α chain (IL-7Rα) and postulated to be critical in T cell development. To directly investigate its function in early thymocyte development, we used GABPα conditional knock-out mice where the exons encoding the Ets DNA-binding domain are flanked with LoxP sites. Ablation of GABPα with the Lck-Cre transgene greatly diminished thymic cellularity, blocked thymocyte development at the double negative 3 (DN3) stage, and resulted in reduced expression of T cell receptor (TCR) β chain in DN4 thymocytes. By chromatin immunoprecipitation, we demonstrated in DN thymocytes that GABPα is associated with transcription initiation sites of genes encoding key molecules in TCR rearrangements. Among these GABP-associated genes, knockdown of GABPα expression by RNA interference diminished expression of DNA ligase IV, Artemis, and Ku80 components in DNA-dependent protein kinase complex. Interestingly, forced expression of prearranged TCR but not IL-7Rα can alleviate the DN3 block in GABPα-targeted mice. Our observations collectively indicate that in addition to regulating IL-7Rα expression, GABP is critically required for TCR rearrangements and hence normal T cell development. PMID:20139079

  5. Schedule for developing Baywide Resource Management Strategies: an agreement commitment report from the Chesapeake Executive Council. Final report

    SciTech Connect

    Not Available

    1988-07-01

    Schedules development of resource-management strategies to ensure that appropriate short- and long-term efforts for restoration and protection are under way Baywide. Includes target dates for developing resource-management strategies for submerged aquatic vegetation, tidal and non-tidal wetlands, waterfowl, finfish, shellfish, and other ecologically-valuable species.

  6. Developing an operational rangeland water requirement satisfaction index

    USGS Publications Warehouse

    Senay, Gabriel B.; Verdin, James P.; Rowland, James

    2011-01-01

    Developing an operational water requirement satisfaction index (WRSI) for rangeland monitoring is an important goal of the famine early warning systems network. An operational WRSI has been developed for crop monitoring, but until recently a comparable WRSI for rangeland was not successful because of the extremely poor performance of the index when based on published crop coefficients (K c) for rangelands. To improve the rangeland WRSI, we developed a simple calibration technique that adjusts the K c values for rangeland monitoring using long-term rainfall distribution and reference evapotranspiration data. The premise for adjusting the K c values is based on the assumption that a viable rangeland should exhibit above-average WRSI (values >80%) during a normal year. The normal year was represented by a median dekadal rainfall distribution (satellite rainfall estimate from 1996 to 2006). Similarly, a long-term average for potential evapotranspiration was used as input to the famine early warning systems network WRSI model in combination with soil-water-holding capacity data. A dekadal rangeland WRSI has been operational for east and west Africa since 2005. User feedback has been encouraging, especially with regard to the end-of-season WRSI anomaly products that compare the index's performance to ‘normal’ years. Currently, rangeland WRSI products are generated on a dekadal basis and posted for free distribution on the US Geological Survey early warning website at http://earlywarning.usgs.gov/adds/

  7. Software requirements specification document for the AREST code development

    SciTech Connect

    Engel, D.W.; McGrail, B.P.; Whitney, P.D.; Gray, W.J.; Williford, R.E.; White, M.D.; Eslinger, P.W.; Altenhofen, M.K.

    1993-11-01

    The Analysis of the Repository Source Term (AREST) computer code was selected in 1992 by the U.S. Department of Energy. The AREST code will be used to analyze the performance of an underground high level nuclear waste repository. The AREST code is being modified by the Pacific Northwest Laboratory (PNL) in order to evaluate the engineered barrier and waste package designs, model regulatory compliance, analyze sensitivities, and support total systems performance assessment modeling. The current version of the AREST code was developed to be a very useful tool for analyzing model uncertainties and sensitivities to input parameters. The code has also been used successfully in supplying source-terms that were used in a total systems performance assessment. The current version, however, has been found to be inadequate for the comparison and selection of a design for the waste package. This is due to the assumptions and simplifications made in the selection of the process and system models. Thus, the new version of the AREST code will be designed to focus on the details of the individual processes and implementation of more realistic models. This document describes the requirements of the new models that will be implemented. Included in this document is a section describing the near-field environmental conditions for this waste package modeling, description of the new process models that will be implemented, and a description of the computer requirements for the new version of the AREST code.

  8. Development of a Thrust Stand to Meet LISA Mission Requirements

    NASA Technical Reports Server (NTRS)

    Willis, William D., III; Zakrzwski, Charles M.; Merkowitz, Stephen M.

    2002-01-01

    A thrust stand has been built to measure the force-noise produced by electrostatic micro-Newton (muN) thrusters. The LISA mission's Disturbance Reduction System (DRS) requires thrusters that are capable of producing continuous thrust levels between 1-100 muN with a resolution of 0.1 muN. The stationary force-noise produced by these thrusters must not exceed 0.1 muN/dHz in the measurement bandwidth 10(exp -4) to 1 Hz. The LISA Thrust Stand (LTS) is a torsion-balance type thrust stand designed to meet the following requirements: stationary force-noise measurements from l0( -4) to 1 Hz with 0.1 muN/dHz sensitivity, absolute thrust measurements from 1-100 muN with better than 0.1 muN resolution, and dynamic thruster response from to 10 Hz. The LTS employs a unique vertical configuration, autocollimator for angular position measurements, and electrostatic actuators that are used for dynamic pendulum control and null-mode measurements. Force-noise levels are measured indirectly by characterizing the thrust stand as a spring-mass system. The LTS was initially designed to test the indium FEEP thruster developed by the Austrian Research Center in Seibersdorf (ARCS), but can be modified for testing other thrusters of this type.

  9. Developing operational safety requirements for non-nuclear facilities

    SciTech Connect

    Mahn, J.A.

    1997-11-01

    Little guidance has been provided by the DOE for developing appropriate Operational Safety Requirements (OSR) for non-nuclear facility safety documents. For a period of time, Chapter 2 of DOE/AL Supplemental Order 5481.lB provided format guidance for non-reactor nuclear facility OSRs when this supplemental order applied to both nuclear and non-nuclear facilities. Thus, DOE Albuquerque Operations Office personnel still want to see non-nuclear facility OSRs in accordance with the supplemental order (i.e., in terms of Safety Limits, Limiting Conditions for Operation, and Administrative Controls). Furthermore, they want to see a clear correlation between the OSRs and the results of a facility safety analysis. This paper demonstrates how OSRs can be rather simply derived from the results of a risk assessment performed using the ``binning`` methodology of SAND95-0320.

  10. Fgf19 is required for zebrafish lens and retina development.

    PubMed

    Nakayama, Yoshiaki; Miyake, Ayumi; Nakagawa, Yu; Mido, Tomotaka; Yoshikawa, Maya; Konishi, Morichika; Itoh, Nobuyuki

    2008-01-15

    Fgf signaling plays crucial roles in morphogenesis. Fgf19 is required for zebrafish forebrain development. Here, we examined the roles of Fgf19 in the formation of the lens and retina in zebrafish. Knockdown of Fgf19 caused a size reduction of the lens and the retina, failure of closure of the choroids fissure, and a progressive expansion of the retinal tissue to the midline of the forebrain. Fgf19 expressed in the nasal retina and lens was involved in cell survival but not cell proliferation during embryonic lens and retina development. Fgf19 was essential for the differentiation of lens fiber cells in the lens but not for the neuronal differentiation and lamination in the retina. Loss of nasal fate in the retina caused by the knockdown of Fgf19, expansion of nasal fate in the retina caused by the overexpression of Fgf19 and eye transplantation indicated that Fgf19 in the retina was crucial for the nasal-temporal patterning of the retina that is critical for the guidance of retinal ganglion cell axons. Knockdown of Fgf19 also caused incorrect axon pathfinding. The present findings indicate that Fgf19 positively regulates the patterning and growth of the retina, and the differentiation and growth of the lens in zebrafish.

  11. Developing Metadata Requirements for NASA Airborne Field Campaigns

    NASA Astrophysics Data System (ADS)

    Parker, L.; Rinsland, P. L.; Kusterer, J.; Chen, G.; Early, A. B.; Beach, A. L., III; Wang, D.; Typanski, N. D.; Rutherford, M.; Rieflin, E.

    2014-12-01

    The common definition of metadata is "data about data". NASA has developed metadata formats to meet the needs of its satellite missions and emerging users. Coverage of satellite missions is highly predictable based on orbit characteristics. Airborne missions feature complicated flight patterns to maximize science return and changes in the instrument suites. More relevant to the airborne science data holding, the metadata describes the airborne measurements, in terms of measurement location, time, platform, and instruments. The metadata organizes the data holdings and facilitates the data ordering process from the DAAC. Therefore, the metadata requirements will need to fit the type of airborne measurements and sampling strategies as well as leverage current Earth Science and Data Information System infrastructure (ECHO/Reverb, GCMD). Current airborne data is generated/produced in a variety of formats (ICARRT, ASCII, etc) with the metadata information embedded in the data file. Special readers are needed to parse data file to generate metadata needed for search and discovery. With loosely defined standards within the airborne community this process poses challenges to the data providers. It is necessary to assess the suitability of current metadata standards, which have been mostly developed for satellite observations. To be presented are the use case-based assessments of the current airborne metadata standards and suggestions for future changes.

  12. Asterless is required for centriole length control and sperm development

    PubMed Central

    Galletta, Brian J.; Jacobs, Katherine C.; Fagerstrom, Carey J.

    2016-01-01

    Centrioles are the foundation of two organelles, centrosomes and cilia. Centriole numbers and functions are tightly controlled, and mutations in centriole proteins are linked to a variety of diseases, including microcephaly. Loss of the centriole protein Asterless (Asl), the Drosophila melanogaster orthologue of Cep152, prevents centriole duplication, which has limited the study of its nonduplication functions. Here, we identify populations of cells with Asl-free centrioles in developing Drosophila tissues, allowing us to assess its duplication-independent function. We show a role for Asl in controlling centriole length in germline and somatic tissue, functioning via the centriole protein Cep97. We also find that Asl is not essential for pericentriolar material recruitment or centrosome function in organizing mitotic spindles. Lastly, we show that Asl is required for proper basal body function and spermatid axoneme formation. Insights into the role of Asl/Cep152 beyond centriole duplication could help shed light on how Cep152 mutations lead to the development of microcephaly. PMID:27185836

  13. Ferritin Is Required in Multiple Tissues during Drosophila melanogaster Development

    PubMed Central

    Blowes, Liisa M.; Missirlis, Fanis; Riesgo-Escovar, Juan R.

    2015-01-01

    In Drosophila melanogaster, iron is stored in the cellular endomembrane system inside a protein cage formed by 24 ferritin subunits of two types (Fer1HCH and Fer2LCH) in a 1:1 stoichiometry. In larvae, ferritin accumulates in the midgut, hemolymph, garland, pericardial cells and in the nervous system. Here we present analyses of embryonic phenotypes for mutations in Fer1HCH, Fer2LCH and in both genes simultaneously. Mutations in either gene or deletion of both genes results in a similar set of cuticular embryonic phenotypes, ranging from non-deposition of cuticle to defects associated with germ band retraction, dorsal closure and head involution. A fraction of ferritin mutants have embryonic nervous systems with ventral nerve cord disruptions, misguided axonal projections and brain malformations. Ferritin mutants die with ectopic apoptotic events. Furthermore, we show that ferritin maternal contribution, which varies reflecting the mother’s iron stores, is used in early development. We also evaluated phenotypes arising from the blockage of COPII transport from the endoplasmic reticulum to the Golgi apparatus, feeding the secretory pathway, plus analysis of ectopically expressed and fluorescently marked Fer1HCH and Fer2LCH. Overall, our results are consistent with insect ferritin combining three functions: iron storage, intercellular iron transport, and protection from iron-induced oxidative stress. These functions are required in multiple tissues during Drosophila embryonic development. PMID:26192321

  14. FGF-16 is required for embryonic heart development

    PubMed Central

    Lu, Shun Yan; Sheikh, Farah; Sheppard, Patricia C.; Fresnoza, Agnes; Duckworth, Mary Lynn; Detillieux, Karen A.; Cattini, Peter A.

    2016-01-01

    Fibroblast growth factor 16 (FGF-16) expression has previously been detected in mouse heart at mid-gestation in the endocardium and epicardium, suggesting a role in embryonic heart development. More specifically, exogenously applied FGF-16 has been shown to stimulate growth of embryonic myocardial cells in tissue explants. We have generated mice lacking FGF-16 by targeting the Fgf16 locus on the X chromosome. Elimination of Fgf16 expression resulted in embryonic death as early as day 11.5 (E11.5). External abnormalities, including hemorrhage in the heart and ventral body region as well as facial defects, began to appear in null embryos from E11.5. Morphological analysis of FGF-16 null hearts revealed cardiac defects including chamber dilation, thinning of the atrial and ventricular walls, and poor trabeculation, which were visible at E10.5 and more pronounced at E11.5. These findings indicate FGF-16 is required for embryonic heart development in mid-gestation through its positive effect on myocardial growth. PMID:18565327

  15. Ferritin Is Required in Multiple Tissues during Drosophila melanogaster Development.

    PubMed

    González-Morales, Nicanor; Mendoza-Ortíz, Miguel Ángel; Blowes, Liisa M; Missirlis, Fanis; Riesgo-Escovar, Juan R

    2015-01-01

    In Drosophila melanogaster, iron is stored in the cellular endomembrane system inside a protein cage formed by 24 ferritin subunits of two types (Fer1HCH and Fer2LCH) in a 1:1 stoichiometry. In larvae, ferritin accumulates in the midgut, hemolymph, garland, pericardial cells and in the nervous system. Here we present analyses of embryonic phenotypes for mutations in Fer1HCH, Fer2LCH and in both genes simultaneously. Mutations in either gene or deletion of both genes results in a similar set of cuticular embryonic phenotypes, ranging from non-deposition of cuticle to defects associated with germ band retraction, dorsal closure and head involution. A fraction of ferritin mutants have embryonic nervous systems with ventral nerve cord disruptions, misguided axonal projections and brain malformations. Ferritin mutants die with ectopic apoptotic events. Furthermore, we show that ferritin maternal contribution, which varies reflecting the mother's iron stores, is used in early development. We also evaluated phenotypes arising from the blockage of COPII transport from the endoplasmic reticulum to the Golgi apparatus, feeding the secretory pathway, plus analysis of ectopically expressed and fluorescently marked Fer1HCH and Fer2LCH. Overall, our results are consistent with insect ferritin combining three functions: iron storage, intercellular iron transport, and protection from iron-induced oxidative stress. These functions are required in multiple tissues during Drosophila embryonic development.

  16. 40 CFR 790.60 - Contents of consent agreements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... which testing will be required. (3) The names and addresses of each manufacturer and/or processor who will sign the agreement. (4) The name and address of the manufacturer, processor or other entity who... development of test data. (7) A requirement that testing will be conducted in accordance with the EPA...

  17. 28 CFR 56.2 - Maintenance of records with respect to meetings held to develop voluntary agreements or plans of...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... to the Department of Energy. The Department of Energy may, upon written notice to potential... International Energy Program. 56.2 Section 56.2 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) INTERNATIONAL ENERGY PROGRAM § 56.2 Maintenance of records with respect to meetings held to develop...

  18. Proline is required for male gametophyte development in Arabidopsis

    PubMed Central

    2012-01-01

    . Conclusions Our data show that the development of the male gametophyte carrying mutations in both P5CS1 and P5CS2 is severely compromised, and indicate that proline is required for pollen development and transmission. PMID:23234543

  19. Successful associateship agreements.

    PubMed

    Crafton, B C

    1997-08-01

    When evaluating potential associateship agreements, dentists need to recognize and understand how status, noncompete clauses, scheduling and compensation affect the strength of an associateship agreement. Dentists should not enter an associateship agreement without fully understanding the agreement and its obligations or without the help of an accountant and an attorney.

  20. 2 CFR 782.500 - Who in USAID determines that a recipient other than an individual violated the requirements of...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Agreements Federal Agency Regulations for Grants and Agreements AGENCY FOR INTERNATIONAL DEVELOPMENT REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Violations of This Part and Consequences §...

  1. 2 CFR 782.500 - Who in USAID determines that a recipient other than an individual violated the requirements of...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Agreements Federal Agency Regulations for Grants and Agreements AGENCY FOR INTERNATIONAL DEVELOPMENT REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Violations of This Part and Consequences §...

  2. 2 CFR 782.500 - Who in USAID determines that a recipient other than an individual violated the requirements of...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Agreements Federal Agency Regulations for Grants and Agreements AGENCY FOR INTERNATIONAL DEVELOPMENT REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Violations of This Part and Consequences §...

  3. Spacelab user implementation assessment study. Volume 3: Resource requirements development

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The resources requirements for the integration and checkout of spacelab payloads are presented in three categories: mission-unique, sustaining, and non-recurring. The requirements are identified by concept and by center. Cost estimates for the resource requirements are also presented.

  4. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Project agreement. 710.307 Section 710.307 Highways... REAL ESTATE Project Development § 710.307 Project agreement. As a condition of Federal-aid, the STD... project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on...

  5. 45 CFR 1155.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Cooperative agreement. 1155.620 Section 1155.620... ASSISTANCE) Definitions § 1155.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  6. 22 CFR 312.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Cooperative agreement. 312.620 Section 312.620...) Definitions § 312.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  7. 22 CFR 1008.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Cooperative agreement. 1008.620 Section 1008.620... ASSISTANCE) Definitions § 1008.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  8. 36 CFR 1212.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false Cooperative agreement. 1212... § 1212.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  9. 36 CFR 1212.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Cooperative agreement. 1212... § 1212.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  10. 22 CFR 133.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Cooperative agreement. 133.620 Section 133.620... (FINANCIAL ASSISTANCE) Definitions § 133.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  11. 34 CFR 84.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 1 2014-07-01 2014-07-01 false Cooperative agreement. 84.620 Section 84.620 Education... (FINANCIAL ASSISTANCE) Definitions § 84.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C....

  12. 45 CFR 1155.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Cooperative agreement. 1155.620 Section 1155.620... ASSISTANCE) Definitions § 1155.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  13. 34 CFR 84.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 1 2012-07-01 2012-07-01 false Cooperative agreement. 84.620 Section 84.620 Education... (FINANCIAL ASSISTANCE) Definitions § 84.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C....

  14. 22 CFR 312.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Cooperative agreement. 312.620 Section 312.620...) Definitions § 312.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  15. 22 CFR 1509.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Cooperative agreement. 1509.620 Section 1509.620... (FINANCIAL ASSISTANCE) Definitions § 1509.620 Cooperative agreement. Cooperative agreement means an award of... award. The term does not include cooperative research and development agreements as defined in 15...

  16. 20 CFR 439.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Cooperative agreement. 439.620 Section 439... WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 439.620 Cooperative agreement. Cooperative agreement means an... contemplated by the award. The term does not include cooperative research and development agreements as...

  17. 22 CFR 1008.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Cooperative agreement. 1008.620 Section 1008.620... ASSISTANCE) Definitions § 1008.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  18. 22 CFR 1008.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Cooperative agreement. 1008.620 Section 1008.620... ASSISTANCE) Definitions § 1008.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  19. 45 CFR 1155.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Cooperative agreement. 1155.620 Section 1155.620... ASSISTANCE) Definitions § 1155.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  20. 49 CFR 32.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 1 2012-10-01 2012-10-01 false Cooperative agreement. 32.620 Section 32.620... (FINANCIAL ASSISTANCE) Definitions § 32.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  1. 29 CFR 94.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Cooperative agreement. 94.620 Section 94.620 Labor Office...) Definitions § 94.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  2. 45 CFR 1173.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Cooperative agreement. 1173.620 Section 1173.620... (FINANCIAL ASSISTANCE) Definitions § 1173.620 Cooperative agreement. Cooperative agreement means an award of... award. The term does not include cooperative research and development agreements as defined in 15...

  3. 21 CFR 1405.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Cooperative agreement. 1405.620 Section 1405.620... WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1405.620 Cooperative agreement. Cooperative agreement means... contemplated by the award. The term does not include cooperative research and development agreements as...

  4. 49 CFR 32.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Cooperative agreement. 32.620 Section 32.620... (FINANCIAL ASSISTANCE) Definitions § 32.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  5. 22 CFR 312.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Cooperative agreement. 312.620 Section 312.620...) Definitions § 312.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  6. 36 CFR 1212.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false Cooperative agreement. 1212... § 1212.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  7. 45 CFR 1155.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Cooperative agreement. 1155.620 Section 1155.620... ASSISTANCE) Definitions § 1155.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  8. 21 CFR 1405.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Cooperative agreement. 1405.620 Section 1405.620... WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1405.620 Cooperative agreement. Cooperative agreement means... contemplated by the award. The term does not include cooperative research and development agreements as...

  9. 28 CFR 83.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Cooperative agreement. 83.620 Section 83...-FREE WORKPLACE (GRANTS) Definitions § 83.620 Cooperative agreement. Cooperative agreement means an... by the award. The term does not include cooperative research and development agreements as defined...

  10. 29 CFR 94.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 1 2013-07-01 2013-07-01 false Cooperative agreement. 94.620 Section 94.620 Labor Office...) Definitions § 94.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  11. 22 CFR 133.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Cooperative agreement. 133.620 Section 133.620... (FINANCIAL ASSISTANCE) Definitions § 133.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  12. 45 CFR 1155.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Cooperative agreement. 1155.620 Section 1155.620... ASSISTANCE) Definitions § 1155.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  13. 36 CFR 1212.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true Cooperative agreement. 1212... § 1212.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  14. 21 CFR 1405.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Cooperative agreement. 1405.620 Section 1405.620... WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1405.620 Cooperative agreement. Cooperative agreement means... contemplated by the award. The term does not include cooperative research and development agreements as...

  15. 22 CFR 210.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Cooperative agreement. 210.620 Section 210.620... (FINANCIAL ASSISTANCE) Definitions § 210.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  16. 28 CFR 83.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Cooperative agreement. 83.620 Section 83...-FREE WORKPLACE (GRANTS) Definitions § 83.620 Cooperative agreement. Cooperative agreement means an... by the award. The term does not include cooperative research and development agreements as defined...

  17. 49 CFR 32.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false Cooperative agreement. 32.620 Section 32.620... (FINANCIAL ASSISTANCE) Definitions § 32.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  18. 22 CFR 133.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Cooperative agreement. 133.620 Section 133.620... (FINANCIAL ASSISTANCE) Definitions § 133.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  19. 28 CFR 83.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Cooperative agreement. 83.620 Section 83...-FREE WORKPLACE (GRANTS) Definitions § 83.620 Cooperative agreement. Cooperative agreement means an... by the award. The term does not include cooperative research and development agreements as defined...

  20. 22 CFR 312.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Cooperative agreement. 312.620 Section 312.620...) Definitions § 312.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  1. 22 CFR 1509.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Cooperative agreement. 1509.620 Section 1509.620... (FINANCIAL ASSISTANCE) Definitions § 1509.620 Cooperative agreement. Cooperative agreement means an award of... award. The term does not include cooperative research and development agreements as defined in 15...

  2. 22 CFR 133.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Cooperative agreement. 133.620 Section 133.620... (FINANCIAL ASSISTANCE) Definitions § 133.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  3. 7 CFR 3021.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 15 2011-01-01 2011-01-01 false Cooperative agreement. 3021.620 Section 3021.620...) Definitions § 3021.620 Cooperative agreement. Cooperative agreement means an award of financial assistance... not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  4. 49 CFR 32.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false Cooperative agreement. 32.620 Section 32.620... (FINANCIAL ASSISTANCE) Definitions § 32.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  5. 36 CFR 1212.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Cooperative agreement. 1212... § 1212.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  6. 29 CFR 94.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Cooperative agreement. 94.620 Section 94.620 Labor Office of...) Definitions § 94.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  7. 49 CFR 32.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 1 2014-10-01 2014-10-01 false Cooperative agreement. 32.620 Section 32.620... (FINANCIAL ASSISTANCE) Definitions § 32.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  8. 21 CFR 1405.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Cooperative agreement. 1405.620 Section 1405.620... WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1405.620 Cooperative agreement. Cooperative agreement means... contemplated by the award. The term does not include cooperative research and development agreements as...

  9. 22 CFR 1509.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Cooperative agreement. 1509.620 Section 1509.620... (FINANCIAL ASSISTANCE) Definitions § 1509.620 Cooperative agreement. Cooperative agreement means an award of... award. The term does not include cooperative research and development agreements as defined in 15...

  10. 22 CFR 312.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Cooperative agreement. 312.620 Section 312.620...) Definitions § 312.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  11. 28 CFR 83.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Cooperative agreement. 83.620 Section 83...-FREE WORKPLACE (GRANTS) Definitions § 83.620 Cooperative agreement. Cooperative agreement means an... by the award. The term does not include cooperative research and development agreements as defined...

  12. 22 CFR 133.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Cooperative agreement. 133.620 Section 133.620... (FINANCIAL ASSISTANCE) Definitions § 133.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  13. 28 CFR 83.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Cooperative agreement. 83.620 Section 83...-FREE WORKPLACE (GRANTS) Definitions § 83.620 Cooperative agreement. Cooperative agreement means an... by the award. The term does not include cooperative research and development agreements as defined...

  14. 34 CFR 84.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 1 2013-07-01 2013-07-01 false Cooperative agreement. 84.620 Section 84.620 Education... (FINANCIAL ASSISTANCE) Definitions § 84.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C....

  15. 29 CFR 94.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Cooperative agreement. 94.620 Section 94.620 Labor Office of...) Definitions § 94.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  16. 22 CFR 210.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Cooperative agreement. 210.620 Section 210.620... (FINANCIAL ASSISTANCE) Definitions § 210.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  17. 22 CFR 1509.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Cooperative agreement. 1509.620 Section 1509.620... (FINANCIAL ASSISTANCE) Definitions § 1509.620 Cooperative agreement. Cooperative agreement means an award of... award. The term does not include cooperative research and development agreements as defined in 15...

  18. 29 CFR 94.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 1 2012-07-01 2012-07-01 false Cooperative agreement. 94.620 Section 94.620 Labor Office...) Definitions § 94.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that... cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  19. 22 CFR 1008.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Cooperative agreement. 1008.620 Section 1008.620... ASSISTANCE) Definitions § 1008.620 Cooperative agreement. Cooperative agreement means an award of financial... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  20. 34 CFR 84.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Cooperative agreement. 84.620 Section 84.620 Education... (FINANCIAL ASSISTANCE) Definitions § 84.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C....

  1. 34 CFR 84.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 1 2011-07-01 2011-07-01 false Cooperative agreement. 84.620 Section 84.620 Education... (FINANCIAL ASSISTANCE) Definitions § 84.620 Cooperative agreement. Cooperative agreement means an award of... term does not include cooperative research and development agreements as defined in 15 U.S.C....

  2. 7 CFR 3021.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Cooperative agreement. 3021.620 Section 3021.620...) Definitions § 3021.620 Cooperative agreement. Cooperative agreement means an award of financial assistance... not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  3. 7 CFR 3021.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false Cooperative agreement. 3021.620 Section 3021.620...) Definitions § 3021.620 Cooperative agreement. Cooperative agreement means an award of financial assistance... not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  4. 22 CFR 1008.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Cooperative agreement. 1008.620 Section 1008... (FINANCIAL ASSISTANCE) Definitions § 1008.620 Cooperative agreement. Cooperative agreement means an award of... award. The term does not include cooperative research and development agreements as defined in 15...

  5. 22 CFR 1509.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Cooperative agreement. 1509.620 Section 1509... WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1509.620 Cooperative agreement. Cooperative agreement means... contemplated by the award. The term does not include cooperative research and development agreements as...

  6. 21 CFR 1405.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Cooperative agreement. 1405.620 Section 1405.620... WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1405.620 Cooperative agreement. Cooperative agreement means... contemplated by the award. The term does not include cooperative research and development agreements as...

  7. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Project agreement. 710.307 Section 710.307 Highways... REAL ESTATE Project Development § 710.307 Project agreement. As a condition of Federal-aid, the STD... project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on...

  8. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Project agreement. 710.307 Section 710.307 Highways... REAL ESTATE Project Development § 710.307 Project agreement. As a condition of Federal-aid, the STD... project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on...

  9. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Project agreement. 710.307 Section 710.307 Highways... REAL ESTATE Project Development § 710.307 Project agreement. As a condition of Federal-aid, the STD... project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on...

  10. 23 CFR 710.307 - Project agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Project agreement. 710.307 Section 710.307 Highways... REAL ESTATE Project Development § 710.307 Project agreement. As a condition of Federal-aid, the STD... project agreement in accordance with 23 CFR part 630, subpart C. The agreement shall be based on...

  11. 30 CFR 948.30 - State-Federal Cooperative Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 3 2012-07-01 2012-07-01 false State-Federal Cooperative Agreement. 948.30... State-Federal Cooperative Agreement. Cooperative Agreement This is a Cooperative Agreement (Agreement...: Requirements for Cooperative Agreement The Governor and the Secretary affirm that they will comply with all...

  12. 30 CFR 934.30 - State-Federal Cooperative Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 3 2012-07-01 2012-07-01 false State-Federal Cooperative Agreement. 934.30... State-Federal Cooperative Agreement. Cooperative Agreement This is a Cooperative Agreement (Agreement... Hearings and Appeals. Article IV: Requirements for Cooperative Agreement The Commission and the...

  13. 30 CFR 948.30 - State-Federal Cooperative Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 3 2013-07-01 2013-07-01 false State-Federal Cooperative Agreement. 948.30... State-Federal Cooperative Agreement. Cooperative Agreement This is a Cooperative Agreement (Agreement...: Requirements for Cooperative Agreement The Governor and the Secretary affirm that they will comply with all...

  14. 30 CFR 948.30 - State-Federal Cooperative Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 3 2014-07-01 2014-07-01 false State-Federal Cooperative Agreement. 948.30... State-Federal Cooperative Agreement. Cooperative Agreement This is a Cooperative Agreement (Agreement...: Requirements for Cooperative Agreement The Governor and the Secretary affirm that they will comply with all...

  15. 30 CFR 948.30 - State-Federal Cooperative Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 3 2011-07-01 2011-07-01 false State-Federal Cooperative Agreement. 948.30... State-Federal Cooperative Agreement. Cooperative Agreement This is a Cooperative Agreement (Agreement...: Requirements for Cooperative Agreement The Governor and the Secretary affirm that they will comply with all...

  16. 30 CFR 946.30 - State-Federal Cooperative Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 3 2012-07-01 2012-07-01 false State-Federal Cooperative Agreement. 946.30...-Federal Cooperative Agreement. This is a Cooperative Agreement (Agreement) between the Commonwealth of... lands with cooperative agreement. Article V: Requirements for Cooperative Agreement The Governor and...

  17. 30 CFR 946.30 - State-Federal Cooperative Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 3 2013-07-01 2013-07-01 false State-Federal Cooperative Agreement. 946.30...-Federal Cooperative Agreement. This is a Cooperative Agreement (Agreement) between the Commonwealth of... lands with cooperative agreement. Article V: Requirements for Cooperative Agreement The Governor and...

  18. 30 CFR 946.30 - State-Federal Cooperative Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 3 2014-07-01 2014-07-01 false State-Federal Cooperative Agreement. 946.30...-Federal Cooperative Agreement. This is a Cooperative Agreement (Agreement) between the Commonwealth of... lands with cooperative agreement. Article V: Requirements for Cooperative Agreement The Governor and...

  19. 30 CFR 934.30 - State-Federal Cooperative Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 3 2013-07-01 2013-07-01 false State-Federal Cooperative Agreement. 934.30... State-Federal Cooperative Agreement. Cooperative Agreement This is a Cooperative Agreement (Agreement... Hearings and Appeals. Article IV: Requirements for Cooperative Agreement The Commission and the...

  20. The Development of Project Orion Ground Safety Requirements

    NASA Technical Reports Server (NTRS)

    Kirkpatrick, Paul; Condzella, Bill; Williams, Jeff

    2011-01-01

    In spite of a very compressed schedule, Project Orion's AFT safety team was able to pull together a comprehensive set of ground safety requirements using existing requirements and subject matter experts. These requirements will serve as the basis for the design of GSE and ground operations. Using the above lessons as a roadmap, new Projects can produce the same results. A rigorous set of ground safety requirements is required to assure ground support equipment (GSE) and associated flight hardware ground operations are conducted safety

  1. Deciphering animal development through proteomics: requirements and prospects.

    PubMed

    Reintsch, Wolfgang E; Mandato, Craig A

    2008-07-24

    In recent years proteomic techniques have started to become very useful tools in a variety of model systems of developmental biology. Applications cover many different aspects of development, including the characterization of changes in the proteome during early embryonic stages. During early animal development the embryo becomes patterned through the temporally and spatially controlled activation of distinct sets of genes. Patterning information is then translated, from gastrulation onwards, into regional specific morphogenetic cell and tissue movements that give the embryo its characteristic shape. On the molecular level, patterning is the outcome of intercellular communication via signaling molecules and the local activation or repression of transcription factors. Genetic approaches have been used very successfully to elucidate the processes behind these events. Morphogenetic movements, on the other hand, have to be orchestrated through regional changes in the mechanical properties of cells. The molecular mechanisms that govern these changes have remained much more elusive, at least in part due to the fact that they are more under translational/posttranslational control than patterning events. However, recent studies indicate that proteomic approaches can provide the means to finally unravel the mechanisms that link patterning to the generation of embryonic form. To intensify research in this direction will require close collaboration between proteome scientists and developmental researchers. It is with this aim in mind that we first give an outline of the classical questions of patterning and morphogenesis. We then summarize the proteomic approaches that have been applied in developmental model systems and describe the pioneering studies that have been done to study morphogenesis. Finally we discuss current and future strategies that will allow characterizing the changes in the embryonic proteome and ultimately lead to a deeper understanding of the cellular

  2. Deciphering animal development through proteomics: requirements and prospects

    PubMed Central

    Reintsch, Wolfgang E; Mandato, Craig A

    2008-01-01

    In recent years proteomic techniques have started to become very useful tools in a variety of model systems of developmental biology. Applications cover many different aspects of development, including the characterization of changes in the proteome during early embryonic stages. During early animal development the embryo becomes patterned through the temporally and spatially controlled activation of distinct sets of genes. Patterning information is then translated, from gastrulation onwards, into regional specific morphogenetic cell and tissue movements that give the embryo its characteristic shape. On the molecular level, patterning is the outcome of intercellular communication via signaling molecules and the local activation or repression of transcription factors. Genetic approaches have been used very successfully to elucidate the processes behind these events. Morphogenetic movements, on the other hand, have to be orchestrated through regional changes in the mechanical properties of cells. The molecular mechanisms that govern these changes have remained much more elusive, at least in part due to the fact that they are more under translational/posttranslational control than patterning events. However, recent studies indicate that proteomic approaches can provide the means to finally unravel the mechanisms that link patterning to the generation of embryonic form. To intensify research in this direction will require close collaboration between proteome scientists and developmental researchers. It is with this aim in mind that we first give an outline of the classical questions of patterning and morphogenesis. We then summarize the proteomic approaches that have been applied in developmental model systems and describe the pioneering studies that have been done to study morphogenesis. Finally we discuss current and future strategies that will allow characterizing the changes in the embryonic proteome and ultimately lead to a deeper understanding of the cellular

  3. Agreement with the Department of Defense model provisions for CERCLA Federal facilities agreements. Final report

    SciTech Connect

    Not Available

    1988-06-17

    The directive provides model language for inclusion in CERCLA section 120 agreements with the Department of Defense (DOD). The provisions deal primarily with policy issues that require agreement between EPA and DOD before site-specific agreements can be finalized. CERCLA section 120 agreements should be utilized for National Priorities List sites where CERCLA is selected as the lead remedial authority.

  4. Developing Formal Correctness Properties from Natural Language Requirements

    NASA Technical Reports Server (NTRS)

    Nikora, Allen P.

    2006-01-01

    This viewgraph presentation reviews the rationale of the program to transform natural language specifications into formal notation.Specifically, automate generation of Linear Temporal Logic (LTL)correctness properties from natural language temporal specifications. There are several reasons for this approach (1) Model-based techniques becoming more widely accepted, (2) Analytical verification techniques (e.g., model checking, theorem proving) significantly more effective at detecting types of specification design errors (e.g., race conditions, deadlock) than manual inspection, (3) Many requirements still written in natural language, which results in a high learning curve for specification languages, associated tools and increased schedule and budget pressure on projects reduce training opportunities for engineers, and (4) Formulation of correctness properties for system models can be a difficult problem. This has relevance to NASA in that it would simplify development of formal correctness properties, lead to more widespread use of model-based specification, design techniques, assist in earlier identification of defects and reduce residual defect content for space mission software systems. The presentation also discusses: potential applications, accomplishments and/or technological transfer potential and the next steps.

  5. Innovative Approach for Developing Spacecraft Interior Acoustic Requirement Allocation

    NASA Technical Reports Server (NTRS)

    Chu, S. Reynold; Dandaroy, Indranil; Allen, Christopher S.

    2016-01-01

    The Orion Multi-Purpose Crew Vehicle (MPCV) is an American spacecraft for carrying four astronauts during deep space missions. This paper describes an innovative application of Power Injection Method (PIM) for allocating Orion cabin continuous noise Sound Pressure Level (SPL) limits to the sound power level (PWL) limits of major noise sources in the Environmental Control and Life Support System (ECLSS) during all mission phases. PIM is simulated using both Statistical Energy Analysis (SEA) and Hybrid Statistical Energy Analysis-Finite Element (SEA-FE) models of the Orion MPCV to obtain the transfer matrix from the PWL of the noise sources to the acoustic energies of the receivers, i.e., the cavities associated with the cabin habitable volume. The goal of the allocation strategy is to control the total energy of cabin habitable volume for maintaining the required SPL limits. Simulations are used to demonstrate that applying the allocated PWLs to the noise sources in the models indeed reproduces the SPL limits in the habitable volume. The effects of Noise Control Treatment (NCT) on allocated noise source PWLs are investigated. The measurement of source PWLs of involved fan and pump development units are also discussed as it is related to some case-specific details of the allocation strategy discussed here.

  6. U.S. Geological Survey and Microsoft Cooperative Research and Development Agreement: Geospatial Data Browsing and Retrieval Site on the World Wide Web

    USGS Publications Warehouse

    ,

    1998-01-01

    In May 1997, the U.S. Geological Survey (USGS) and the Microsoft Corporation of Redmond, Wash., entered into a cooperative research and development agreement (CRADA) to make vast amounts of geospatial data available to the general public through the Internet. The CRADA is a 36-month joint effort to develop a general, public-oriented browsing and retrieval site for geospatial data on the Internet. Specifically, Microsoft plans to (1) modify a large volume of USGS geospatial data so the images can be displayed quickly and easily over the Internet, (2) implement an easy-to-use interface for low-speed connections, and (3) develop an Internet Web site capable of servicing millions of users per day.

  7. U.S. Geological Survey and Microsoft Cooperative Research and Development Agreement: Geospatial Data Browsing and Retrieval Site on the World Wide Web

    USGS Publications Warehouse

    ,

    1999-01-01

    In May 1997, the U.S. Geological Survey (USGS) and the Microsoft Corporation of Redmond, Wash., entered into a cooperative research and development agreement (CRADA) to make vast amounts of geospatial data available to the general public through the Internet. The CRADA is a 36-month joint effort to develop a general, public-oriented browsing and retrieval site for geospatial data on the Internet. Specifically, Microsoft plans to (1) modify a large volume of USGS geospatial data so the images can be displayed quickly and easily over the Internet, (2) implement an easy-to-use interface for low-speed connections, and (3) develop an Internet Web site capable of servicing millions of users per day.

  8. 38 CFR 48.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Cooperative agreement. 48...) GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 48.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  9. 29 CFR 1472.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 4 2014-07-01 2014-07-01 false Cooperative agreement. 1472.620 Section 1472.620 Labor... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1472.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C. 6305, is used...

  10. 29 CFR 1472.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 4 2013-07-01 2013-07-01 false Cooperative agreement. 1472.620 Section 1472.620 Labor... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1472.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C. 6305, is used...

  11. 14 CFR 1267.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Cooperative agreement. 1267.620 Section... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1267.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C. 6305, is used...

  12. 29 CFR 1472.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 4 2012-07-01 2012-07-01 false Cooperative agreement. 1472.620 Section 1472.620 Labor... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1472.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C. 6305, is used...

  13. 29 CFR 1472.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 4 2011-07-01 2011-07-01 false Cooperative agreement. 1472.620 Section 1472.620 Labor... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1472.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C. 6305, is used...

  14. 45 CFR 630.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Cooperative agreement. 630.620 Section 630.620... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 630.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  15. 45 CFR 630.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Cooperative agreement. 630.620 Section 630.620... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 630.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  16. 38 CFR 48.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Cooperative agreement. 48...) GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 48.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  17. 29 CFR 1472.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Cooperative agreement. 1472.620 Section 1472.620 Labor... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1472.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C. 6305, is used...

  18. 14 CFR 1267.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Cooperative agreement. 1267.620 Section... REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1267.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C. 6305, is used...

  19. 45 CFR 630.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Cooperative agreement. 630.620 Section 630.620... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 630.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  20. 38 CFR 48.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Cooperative agreement. 48...) GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 48.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  1. 38 CFR 48.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Cooperative agreement. 48...) GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 48.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  2. 40 CFR 36.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Cooperative agreement. 36.620 Section... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 36.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  3. 45 CFR 630.620 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Cooperative agreement. 630.620 Section 630.620... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 630.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  4. 45 CFR 630.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Cooperative agreement. 630.620 Section 630.620... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 630.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  5. 38 CFR 48.620 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Cooperative agreement. 48...) GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 48.620 Cooperative agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C....

  6. 14 CFR 1274.207 - Extended agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... as new cooperative agreements. Continued performance within a period specified under a multiple year....207 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION COOPERATIVE AGREEMENTS WITH COMMERCIAL FIRMS Pre-Award Requirements § 1274.207 Extended agreements. (a) Multiple year...

  7. 14 CFR 1274.207 - Extended agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... as new cooperative agreements. Continued performance within a period specified under a multiple year....207 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION COOPERATIVE AGREEMENTS WITH COMMERCIAL FIRMS Pre-Award Requirements § 1274.207 Extended agreements. (a) Multiple year...

  8. 10 CFR 607.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Cooperative agreement. 607.620 Section 607.620 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 607.620 Cooperative agreement. Cooperative agreement means an award...

  9. Child Development Functionality Assessment Guide: Standards and Requirements for Developing Most Efficient Organizations.

    ERIC Educational Resources Information Center

    Department of the Army, Washington, DC.

    As part of its cost containment efforts, the U.S. Navy continues to evaluate its child development program to expand availability without compromising the high quality standards required by the 1989 Military Child Care Act. This manual provides guidelines for conducting Functionality Assessments (FA) and delineates the standards and requirements…

  10. The oil and gas joint operating agreement

    SciTech Connect

    Not Available

    1990-01-01

    This book covers the following topics: introduction to the AAPL model form operating agreement; property provisions of the operating agreement; Article 6---the drilling and development article; duties and obligations revisited---who bear what risk of loss; operator's liens; accounting procedure joint operations; insurance; taking gas in kind absent a balancing agreement; RMMLF Form 5 Gas Balancing Agreement; tax partnerships for nontax professionals; alternative agreement forms.

  11. Oligopeptidase A is required for normal phage P22 development.

    PubMed Central

    Conlin, C A; Vimr, E R; Miller, C G

    1992-01-01

    The opdA gene of Salmonella typhimurium encodes an endoprotease, oligopeptidase A (OpdA). Strains carrying opdA mutations were deficient as hosts for phage P22. P22 and the closely related phages L and A3 formed tiny plaques on an opdA host. Salmonella phages 9NA, KB1, and ES18.h1 were not affected by opdA mutations. Although opdA strains displayed normal doubling times and were infected by P22 as efficiently as opdA+ strains, the burst size of infectious particles from an opdA host was less than 1/10 of that from an opdA+ host. This decrease resulted from a reduced efficiency of plating of particles from an opdA infection. In the absence of a functional opdA gene, most of the P22 particles are defective. To identify the target of OpdA action, P22 mutants which formed plaques larger than wild-type plaques on an opdA mutant lawn were isolated. Marker rescue experiments using cloned fragments of P22 DNA localized these mutations to a 1-kb fragment. The nucleotide sequence of this fragment and a contiguous region (including all of both P22 gene 7 and gene 14) was determined. The mutations leading to opdA independence affected the region of gene 7 coding for the amino terminus of gp7, a protein required for DNA injection by the phage. Comparison of the nucleotide sequence with the N-terminal amino acid sequence of gp7 suggested that a 20-amino-acid peptide is removed from gp7 during phage development. Further experiments showed that this processing was opdA dependent and rapid (half-life, less than 2 min) and occurred in the absence of other phage proteins. The opdA-independent mutations lead to mutant forms of gp7 which function without processing. Images PMID:1522065

  12. Development of requirements for environmental specimen banking in ecological monitoring (exemplified by the Chernobyl NPP accident area).

    PubMed

    Borzilov, V A

    1993-11-01

    Development of requirements for a data bank for natural media as a system of intercorrelated parameters to estimate system states are determined. The problems of functional agreement between experimental and calculation methods are analysed when organizing the ecological monitoring. The methods of forming the environmental specimen bank to estimate and forecast radioactive contamination and exposure dose are considered to be exemplified by the peculiarities of the spatial distribution of radioactive contamination in fields. Analysed is the temporal dynamics of contamination for atmospheric air, soil and water.

  13. 32 CFR 37.1260 - Cooperative agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Definitions of Terms Used in This Part § 37.1260 Cooperative... the cooperative agreement. The term does not include “cooperative research and development...

  14. Exploration Requirements Development Utilizing the Strategy-to-Task-to-Technology Development Approach

    NASA Technical Reports Server (NTRS)

    Drake, Bret G.; Josten, B. Kent; Monell, Donald W.

    2004-01-01

    The Vision for Space Exploration provides direction for the National Aeronautics and Space Administration to embark on a robust space exploration program that will advance the Nation s scientific, security, and economic interests. This plan calls for a progressive expansion of human capabilities beyond low earth orbit seeking to answer profound scientific and philosophical questions while responding to discoveries along the way. In addition, the Vision articulates the strategy for developing the revolutionary new technologies and capabilities required for the future exploration of the solar system. The National Aeronautics and Space Administration faces new challenges in successfully implementing the Vision. In order to implement a sustained and affordable exploration endeavor it is vital for NASA to do business differently. This paper provides an overview of the strategy-to-task-to-technology process being used by NASA s Exploration Systems Mission Directorate to develop the requirements and system acquisition details necessary for implementing a sustainable exploration vision.

  15. 14 CFR 152.111 - Application requirements: Airport development.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... to comply with applicable air and water quality standards. (6) A statement whether any building... TRANSPORTATION (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Eligibility Requirements and Application Procedures § 152... Transportation (49 CFR 25.57 and 25.59), whether or not reimbursement is being requested for the costs...

  16. Student Performance Requirements: Minitary Service. Continuation Education System Development Project.

    ERIC Educational Resources Information Center

    La Puente Union High School District, CA.

    Funded under Title III of the Elementary and Secondary Education Act of 1965, the La Puente, California, continuation education project investigated (1) attitudes of former students concerning the success of the school in preparing them for entry into military service, (2) the minimal skills and knowledge required by each of the armed forces, (3)…

  17. 2 CFR 782.505 - Who in USAID determines that a recipient who is an individual violated the requirements of this...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Agreements Federal Agency Regulations for Grants and Agreements AGENCY FOR INTERNATIONAL DEVELOPMENT REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Violations of This Part and Consequences §...

  18. 2 CFR 782.505 - Who in USAID determines that a recipient who is an individual violated the requirements of this...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Agreements Federal Agency Regulations for Grants and Agreements AGENCY FOR INTERNATIONAL DEVELOPMENT REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Violations of This Part and Consequences §...

  19. 2 CFR 782.505 - Who in USAID determines that a recipient who is an individual violated the requirements of this...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Agreements Federal Agency Regulations for Grants and Agreements AGENCY FOR INTERNATIONAL DEVELOPMENT REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Violations of This Part and Consequences §...

  20. Operon required for fruiting body development in Myxococcus xanthus.

    PubMed

    Kim, Dohee; Chung, Jinwoo; Hyun, Hyesook; Lee, Chayul; Lee, Kyoung; Cho, Kyungyun

    2009-11-01

    We have used mutational analysis to identify four genes, MXAN3553, MXAN3554, MXAN3555, and MXAN3556, constituting an operon that is essential for normal fruiting body development in Myxococcus xanthus. Deletion of MXAN3553, which encoded a hypothetical protein, resulted in delayed fruiting body development. MXAN3554 was predicted to encode a metallopeptidase, and its deletion caused fruiting body formation to fail. Inactivation of MXAN3555, which encoded a putative NtrC-type response regulator, resulted in delayed aggregation and a severe reduction in sporulation. Fruiting bodies also failed to develop with the deletion of MXAN3556, another gene encoding a hypothetical protein.

  1. Geothermal power development in Hawaii. Volume II. Infrastructure and community-services requirements, Island of Hawaii

    SciTech Connect

    Chapman, G.A.; Buevens, W.R.

    1982-06-01

    The requirements of infrastructure and community services necessary to accommodate the development of geothermal energy on the Island of Hawaii for electricity production are identified. The following aspects are covered: Puna District-1981, labor resources, geothermal development scenarios, geothermal land use, the impact of geothermal development on Puna, labor resource requirments, and the requirements for government activity.

  2. Mining agreements III

    SciTech Connect

    Not Available

    1991-01-01

    This book cover the following: Forms of mining agreements; Preliminary letter agreements; Acquisition of mineral interests involving securities; Partnership tax treatment in mining agreements; Non-tax consequences of partnerships under state law; Protection against joint venturers' liabilities; Joint venture decision making; Mining royalties; Commingling and unitization provisions; Indemnification and insurance provisions; Area of interest provision; Dispute resolution; and Non-participation and default provisions.

  3. Osteogenic protein-1 is required for mammalian eye development.

    PubMed

    Solursh, M; Langille, R M; Wood, J; Sampath, T K

    1996-01-17

    Osteogenic Protein-1 (OP-1/BMP-7) is a bone morphogenetic protein in the transforming growth factor-beta superfamily and has been shown to be expressed temporally and spatially during epithelial-mesenchymal interactions mediating tissue morphogenesis in early embryogenesis. In order to identify the primary role(s) for OP-1 in development, we carried out whole rat embryo cultures, over a 72-h period from primitive streak stages to early limb bud stages, in rat sera containing either OP-1 blocking antibodies (10 micrograms/ml) or nonreactive IgG. Rat embryos cultured with control antibodies developed normally, while those cultured with anti-OP-1 antibodies consistently exhibited over-all reduced size and absence of eyes. Histological sections revealed a greater reduction in neural retina development in the embryos treated with anti-OP-1 blocking antibodies. In situ hybridization and immunolocalization analyses indicate that OP-1 is expressed in the neuroepithelium of the optic vesicle at E11.5, is limited to the presumptive neural retina and developing lens placode, and is subsequently expressed in the neural retina, lens and developing cornea at E12.5-E13.5. Our results indicate that OP-1 mediates the inductive signals involved in mammalian eye development.

  4. Requirement of proline synthesis during Arabidopsis reproductive development

    PubMed Central

    2012-01-01

    Background Gamete and embryo development are crucial for successful reproduction and seed set in plants, which is often the determining factor for crop yield. Proline accumulation was largely viewed as a specific reaction to overcome stress conditions, while recent studies suggested important functions of proline metabolism also in reproductive development. Both the level of free proline and proline metabolism were proposed to influence the transition to flowering, as well as pollen and embryo development. Results In this study, we performed a detailed analysis of the contribution of individual proline biosynthetic enzymes to vegetative development and reproductive success in Arabidopsis. In contrast to previous reports, we found that pyrroline-5-carboxylate (P5C) synthetase 2 (P5CS2) is not essential for sexual reproduction although p5cs2 mutant plants were retarded in vegetative development and displayed reduced fertility under long-day conditions. Single mutant plants devoid of P5CS1 did not show any developmental defects. Simultaneous absence of both P5CS isoforms resulted in pollen sterility, while fertile egg cells could still be produced. Expression of P5C reductase (P5CR) was indispensable for embryo development but surprisingly not needed for pollen or egg cell fertility. The latter observation could be explained by an extreme stability of P5CR activity, which had a half-life time of greater than 3 weeks in vitro. Expression of P5CR-GFP under the control of the endogenous P5CR promoter was able to restore growth of homozygous p5cr mutant embryos. The analysis of P5CR-GFP-fluorescence in planta supported an exclusively cytoplasmatic localisation of P5CR. Conclusions Our results demonstrate that potential alternative pathways for proline synthesis or inter-generation transfer of proline are not sufficient to overcome a defect in proline biosynthesis from glutamate during pollen development. Proline biosynthesis through P5CS2 and P5CR is limiting for

  5. Review and Analysis of Development of "Safety by Design" Requirements

    SciTech Connect

    Vance, Scott A.; Hockert, John

    2009-10-20

    This report, the deliverable for Task 4 of the NA-243 Safeguards by Design Work Plan for Fiscal Year 2009, develops the lessons to be learned for the institutionalization of Safeguards By Design (SBD) from the Department of Energy (DOE) experience developing and implementing DOE-STD-1189, Integration of Safety into the Design Process. This experience was selected for study because of the similarity of the challenges of integrating safety and safeguards into the design process. Development of DOE-STD-1189 began in January 2006 and the standard was issued for implementation in March 2008. The process was much more time consuming than originally anticipated and might not have come to fruition had senior DOE management been less committed to its success. Potentially valuable lessons can be learned from both the content and presentation of the integration approach in DOE-STD-1189 and from the DOE experience in developing and implementing DOE-STD-1189. These lessons are important because the instutionalization of SBD does not yet appear to have the level of senior management commitment afforded development and implementation of DOE-STD-1189.

  6. Bayesian inference for agreement measures.

    PubMed

    Vidal, Ignacio; de Castro, Mário

    2016-08-25

    The agreement of different measurement methods is an important issue in several disciplines like, for example, Medicine, Metrology, and Engineering. In this article, some agreement measures, common in the literature, were analyzed from a Bayesian point of view. Posterior inferences for such agreement measures were obtained based on well-known Bayesian inference procedures for the bivariate normal distribution. As a consequence, a general, simple, and effective method is presented, which does not require Markov Chain Monte Carlo methods and can be applied considering a great variety of prior distributions. Illustratively, the method was exemplified using five objective priors for the bivariate normal distribution. A tool for assessing the adequacy of the model is discussed. Results from a simulation study and an application to a real dataset are also reported.

  7. Environmental management for dredging sediments - the requirement of developing nations.

    PubMed

    Manap, Norpadzlihatun; Voulvoulis, Nikolaos

    2015-01-01

    Scientific research has characterized the effects of dredging, an underwater excavation process for navigational purposes or material extraction, and has shown its association with a number of chemical, physical and biological impacts. Due to this, much environmental management has been applied in the dredging industry in order to manage its detrimental effects. However, developing nations may have different approaches towards their dredging environmental management to compare to their companions with higher economic strength. Moreover, scientific evidence to make an informed decision is often lacking, hence affecting the number of research executed at these nations, limiting their efforts to preserve the environment. This paper reviews the dredging environmental impacts and its two important factors, dredging technology and sediment characteristic, that determine the magnitude of impacts through literature review, and discusses the need for a more integrated dredging environmental management to be developed for developing nations.

  8. 32 CFR 37.1260 - Cooperative agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 1 2014-07-01 2014-07-01 false Cooperative agreement. 37.1260 Section 37.1260... REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Definitions of Terms Used in This Part § 37.1260 Cooperative... the cooperative agreement. The term does not include “cooperative research and development...

  9. 32 CFR 37.1260 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false Cooperative agreement. 37.1260 Section 37.1260... REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Definitions of Terms Used in This Part § 37.1260 Cooperative... the cooperative agreement. The term does not include “cooperative research and development...

  10. 32 CFR 37.1260 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Cooperative agreement. 37.1260 Section 37.1260... REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Definitions of Terms Used in This Part § 37.1260 Cooperative... the cooperative agreement. The term does not include “cooperative research and development...

  11. 32 CFR 37.1260 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false Cooperative agreement. 37.1260 Section 37.1260... REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Definitions of Terms Used in This Part § 37.1260 Cooperative... the cooperative agreement. The term does not include “cooperative research and development...

  12. 24 CFR 964.335 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Grant agreement. 964.335 Section... § 964.335 Grant agreement. (a) General. HUD will enter into a grant agreement with the recipients of a Family Investment Centers grant which defines the legal framework for the relationship between HUD and...

  13. 24 CFR 964.215 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Grant agreement. 964.215 Section... Grant agreement. (a) General. HUD shall enter into a grant agreement with the recipient of a technical assistance grant which defines the legal framework for the relationship between HUD and a resident council...

  14. 24 CFR 964.335 - Grant agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Grant agreement. 964.335 Section... § 964.335 Grant agreement. (a) General. HUD will enter into a grant agreement with the recipients of a Family Investment Centers grant which defines the legal framework for the relationship between HUD and...

  15. 24 CFR 964.215 - Grant agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Grant agreement. 964.215 Section... Grant agreement. (a) General. HUD shall enter into a grant agreement with the recipient of a technical assistance grant which defines the legal framework for the relationship between HUD and a resident council...

  16. 24 CFR 964.215 - Grant agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Grant agreement. 964.215 Section... Grant agreement. (a) General. HUD shall enter into a grant agreement with the recipient of a technical assistance grant which defines the legal framework for the relationship between HUD and a resident council...

  17. 24 CFR 964.335 - Grant agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Grant agreement. 964.335 Section... § 964.335 Grant agreement. (a) General. HUD will enter into a grant agreement with the recipients of a Family Investment Centers grant which defines the legal framework for the relationship between HUD and...

  18. 7 CFR 1951.877 - Loan agreements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 14 2014-01-01 2014-01-01 false Loan agreements. 1951.877 Section 1951.877...) PROGRAM REGULATIONS (CONTINUED) SERVICING AND COLLECTIONS Rural Development Loan Servicing § 1951.877 Loan agreements. (a) A loan agreement will have been executed by the RDLF intermediary and OCS or HHS for...

  19. 7 CFR 1951.877 - Loan agreements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 14 2013-01-01 2013-01-01 false Loan agreements. 1951.877 Section 1951.877...) PROGRAM REGULATIONS (CONTINUED) SERVICING AND COLLECTIONS Rural Development Loan Servicing § 1951.877 Loan agreements. (a) A loan agreement will have been executed by the RDLF intermediary and OCS or HHS for...

  20. 7 CFR 1951.877 - Loan agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true Loan agreements. 1951.877 Section 1951.877 Agriculture... REGULATIONS (CONTINUED) SERVICING AND COLLECTIONS Rural Development Loan Servicing § 1951.877 Loan agreements. (a) A loan agreement will have been executed by the RDLF intermediary and OCS or HHS for each...

  1. 24 CFR 964.335 - Grant agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Grant agreement. 964.335 Section... § 964.335 Grant agreement. (a) General. HUD will enter into a grant agreement with the recipients of a Family Investment Centers grant which defines the legal framework for the relationship between HUD and...

  2. 24 CFR 964.215 - Grant agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Grant agreement. 964.215 Section... Grant agreement. (a) General. HUD shall enter into a grant agreement with the recipient of a technical assistance grant which defines the legal framework for the relationship between HUD and a resident council...

  3. Resource Requirements and Costs of Developing and Delivering MOOCs

    ERIC Educational Resources Information Center

    Hollands, Fiona M.; Tirthali, Devayani

    2014-01-01

    Given the ongoing alarm regarding uncontrollable costs of higher education, it would be reasonable to expect not only concern about the impact of MOOCs on educational outcomes, but also systematic efforts to document the resources expended on their development and delivery. However, there is little publicly available information on MOOC costs that…

  4. YY1 Is Required for Germinal Center B Cell Development

    PubMed Central

    Vuyyuru, Raja; Jha, Vibha; Hodewadekar, Suchita; Manser, Tim; Atchison, Michael L.

    2016-01-01

    YY1 has been implicated as a master regulator of germinal center B cell development as YY1 binding sites are frequently present in promoters of germinal center-expressed genes. YY1 is known to be important for other stages of B cell development including the pro-B and pre-B cells stages. To determine if YY1 plays a critical role in germinal center development, we evaluated YY1 expression during B cell development, and used a YY1 conditional knock-out approach for deletion of YY1 in germinal center B cells (CRE driven by the immunoglobulin heavy chain γ1 switch region promoter; γ1-CRE). We found that YY1 is most highly expressed in germinal center B cells and is increased 3 fold in splenic B cells activated by treatment with anti-IgM and anti-CD40. In addition, deletion of the yy1 gene by action of γ1-CRE recombinase resulted in significant loss of GC cells in both un-immunized and immunized contexts with corresponding loss of serum IgG1. Our results show a crucial role for YY1 in the germinal center reaction. PMID:27167731

  5. YY1 Is Required for Germinal Center B Cell Development.

    PubMed

    Banerjee, Anupam; Sindhava, Vishal; Vuyyuru, Raja; Jha, Vibha; Hodewadekar, Suchita; Manser, Tim; Atchison, Michael L

    2016-01-01

    YY1 has been implicated as a master regulator of germinal center B cell development as YY1 binding sites are frequently present in promoters of germinal center-expressed genes. YY1 is known to be important for other stages of B cell development including the pro-B and pre-B cells stages. To determine if YY1 plays a critical role in germinal center development, we evaluated YY1 expression during B cell development, and used a YY1 conditional knock-out approach for deletion of YY1 in germinal center B cells (CRE driven by the immunoglobulin heavy chain γ1 switch region promoter; γ1-CRE). We found that YY1 is most highly expressed in germinal center B cells and is increased 3 fold in splenic B cells activated by treatment with anti-IgM and anti-CD40. In addition, deletion of the yy1 gene by action of γ1-CRE recombinase resulted in significant loss of GC cells in both un-immunized and immunized contexts with corresponding loss of serum IgG1. Our results show a crucial role for YY1 in the germinal center reaction.

  6. Why a True Account of Human Development Requires Exemplar Research

    ERIC Educational Resources Information Center

    Damon, William; Colby, Anne

    2013-01-01

    This chapter uses moral psychology to illustrate why exemplar methods are essential for building a valid, complete understanding of key domains of human development. Social psychological, economic, and biological-evolutionary paradigms for studying morality rely on samples drawn from the general population. This research reveals a bleak picture of…

  7. Commercialization is Required for Sustainable Space Exploration and Development

    NASA Technical Reports Server (NTRS)

    Martin, Gary L.; Olson, John M.

    2009-01-01

    The U.S. Space Exploration policy outlines an exciting new direction in space for human and robotic exploration and development beyond low Earth orbit. Pressed by this new visionary guidance, human civilization will be able to methodically build capabilities to move off Earth and into the solar system in a step-by-step manner, gradually increasing the capability for humans to stay longer in space and move further away from Earth. The new plans call for an implementation that would create an affordable and sustainable program in order to span over generations of explorers, each new generation pushing back the boundaries and building on the foundations laid by the earlier. To create a sustainable program it is important to enable and encourage the development of a selfsupporting commercial space industry leveraging both traditional and non-traditional segments of the industrial base. Governments will not be able to open the space frontier on their own because their goals change over relatively short timescales and because the large costs associated with human spaceflight cannot be sustained. A strong space development industrial sector is needed that can one day support the needs of commercial space enterprises as well as provide capabilities that the National Aeronautics and Space Administration (NASA) and other national space agencies can buy to achieve their exploration goals. This new industrial space sector will someday provide fundamental capabilities like communications, power, logistics, and even cargo and human space transportation, just as commercial companies are able to provide these services on Earth today. To help develop and bolster this new space industrial sector, NASA and other national space agencies can enable and facilitate it in many ways, including reducing risk by developing important technologies necessary for commercialization of space, and as a paying customer, partner, or anchor tenant. This transition from all or mostly government

  8. Specific requirement for CD3ɛ in T cell development

    PubMed Central

    DeJarnette, Jan B.; Sommers, Connie L.; Huang, Kun; Woodside, Kenneth J.; Emmons, Rebecca; Katz, Kenneth; Shores, Elizabeth W.; Love, Paul E.

    1998-01-01

    T cell antigen receptor (TCR) and pre-TCR complexes are composed of clonotypic heterodimers in association with dimers of signal transducing invariant subunits (CD3γ, -δ, -ɛ, and ζ). The role of individual invariant subunits in T cell development has been investigated by generating gene-specific mutations in mice. Mutation of CD3γ, -δ, or ζ results in an incomplete block in development, characterized by reduced numbers of mature T cells that express low levels of TCR. In contrast, mature T cells are absent from CD3ɛ−/− mice, and thymocyte development is arrested at the early CD4−CD8− stage. Although these results suggest that CD3ɛ is essential for pre-TCR and TCR expression/function, their interpretation is complicated by the fact that expression of the CD3γ and CD3δ genes also is reduced in CD3ɛ−/− mice. Thus, it is unclear whether the phenotype of CD3ɛ−/− mice reflects the collective effects of CD3γ, -δ, and -ɛ deficiency. By removing the selectable marker (PGK-NEO) from the targeted CD3ɛ gene via Cre/loxP-mediated recombination, we generated mice that lack CD3ɛ yet retain normal expression of the closely linked CD3γ and CD3δ genes. These (CD3ɛΔ/Δ) mice exhibited an early arrest in T cell development, similar to that of CD3ɛ−/− mice. Moreover, the developmental defect could be rescued by expression of a CD3ɛ transgene. These results identify an essential role for CD3ɛ in T cell development not shared by the CD3γ, CD3δ, or ζ-family proteins and provide further evidence that PGK-NEO can influence the expression of genes in its proximity. PMID:9843989

  9. 43 CFR 414.3 - Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF... of the requirements of this section. (1) The agreement must specify the quantity of Colorado River... that the Storing State's consumptive use of Colorado River water will be decreased by a...

  10. 43 CFR 414.3 - Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF... of the requirements of this section. (1) The agreement must specify the quantity of Colorado River... that the Storing State's consumptive use of Colorado River water will be decreased by a...

  11. 43 CFR 414.3 - Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF... of the requirements of this section. (1) The agreement must specify the quantity of Colorado River... that the Storing State's consumptive use of Colorado River water will be decreased by a...

  12. 43 CFR 414.3 - Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF... of the requirements of this section. (1) The agreement must specify the quantity of Colorado River... that the Storing State's consumptive use of Colorado River water will be decreased by a...

  13. 43 CFR 414.3 - Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF... of the requirements of this section. (1) The agreement must specify the quantity of Colorado River... that the Storing State's consumptive use of Colorado River water will be decreased by a...

  14. Affiliate Agreements in Community Mental Health: Shotgun Weddings?

    ERIC Educational Resources Information Center

    Kane, Thomas J.; Meyer, James, Jr.

    1980-01-01

    The development of affiliate agreements requires an organized and planned approach with specific goals and strategies, taking into account the complex dynamics that operate in inter-organizational relationships. Successful negotiation leads to decisions in the best interest of each partner, not just preservation of the relationship. (JAC)

  15. The Bottom-up Move within Vygotsky's Zone of Proximal Development: A Pedagogical Application for Teaching Agreement in Spanish as a Foreign Language

    ERIC Educational Resources Information Center

    Escandon, Arturo; Sanz, Montserrat

    2011-01-01

    This paper presents the findings of a longitudinal study in which two instructional methods to teach agreement features to first-year university students specializing in Spanish in Japan are compared. On the one hand, the control group was exposed to the traditional top-down teaching of agreement paradigms and were instructed to practice them…

  16. Development of extraocular muscles require early signals from periocular neural crest and the developing eye

    PubMed Central

    Bohnsack, Brenda L.; Gallina, Donika; Thompson, Hannah; Kasprick, Daniel; Lucarelli, Mark J.; Dootz, Gregory; Nelson, Christine; McGonnell, Imelda M.; Kahana, Alon

    2011-01-01

    Purpose Identify and explain morphologic changes of the extraocular muscles (EOMs) in anophthalmic patients. Methods Retrospective chart review of patients with congenital anophthalmia, using MRI and intraoperative findings to characterize EOM morphology. We then employ molecular biology techniques in zebrafish and chick embryos to determine the relationships among the developing eye, periocular neural crest, and EOMs. Results In three human patients with bilateral congenital anophthalmia and preoperative orbital imaging, we observed a spectrum of EOM morphologies ranging from indiscernible muscle tissue to well-formed, organized EOMs. Timing of eye loss in zebrafish and chick embryos correlated with the morphology of EOM organization in the orbit (“eye socket”). In congenitally eyeless Rx3 zebrafish mutants, or following genetic ablation of the cranial neural crest cells, EOMs failed to organize, which was independent of other craniofacial muscle development. Conclusions Orbital development is dependent on interactions between the eye, neural crest, and developing EOMs. Timing of the ocular insult, in relation to neural crest migration and EOM development, is a key determinant of aberrant EOM organization. Additional research will be required to study patients with unilateral and syndromic anophthalmia, and assess for possible differences in clinical outcomes among patients with varied EOM morphology. Clinical relevance The presence and organization of EOMs in anophthalmic sockets may serve as a marker for the timing of genetic or teratogenic insults, improving genetic counseling, and assisting with surgical reconstruction and family counseling efforts. PMID:21482859

  17. Gender agreement and multiple referents.

    PubMed

    Finocchiaro, Chiara; Mahon, Bradford Z; Caramazza, Alfonso

    2008-01-01

    We report a new pattern of usage in current, spoken Italian that has implications for both psycholinguistic models of language production and linguistic theories of language change. In Italian, gender agreement is mandatory for both singular and plural nouns. However, when two or more nouns of different grammatical gender appear in a conjoined noun phrase (NP), masculine plural agreement is required. In this study, we combined on-line and off-line methodologies in order to assess the mechanisms involved in gender marking in the context of multiple referents. The results of two pronoun production tasks showed that plural feminine agreement was significantly more difficult than plural masculine agreement. In a separate study using offline judgements of acceptability, we found that agreement violations in Italian are tolerated more readily in the case of feminine conjoined noun phrases (e.g., la mela e la banana 'the:fem apple:fem and the: fem banana: fem') than masculine conjoined noun phrases (e.g., il fiore e il libro 'the:mas flower: mas and the:mas book:mas'). Implications of these results are discussed both at the level of functional architecture within the language production system and at the level of changes in language use.

  18. Gender agreement and multiple referents

    PubMed Central

    Finocchiaro, Chiara; Mahon, Bradford Z.; Caramazza, Alfonso

    2010-01-01

    We report a new pattern of usage in current, spoken Italian that has implications for both psycholinguistic models of language production and linguistic theories of language change. In Italian, gender agreement is mandatory for both singular and plural nouns. However, when two or more nouns of different grammatical gender appear in a conjoined noun phrase (NP), masculine plural agreement is required. In this study, we combined on-line and off-line methodologies in order to assess the mechanisms involved in gender marking in the context of multiple referents. The results of two pronoun production tasks showed that plural feminine agreement was significantly more difficult than plural masculine agreement. In a separate study using offline judgements of acceptability, we found that agreement violations in Italian are tolerated more readily in the case of feminine conjoined noun phrases (e.g., la mela e la banana ‘the:fem apple:fem and the: fem banana: fem’) than masculine conjoined noun phrases (e.g., il fiore e il libro ‘the:mas flower: mas and the:mas book:mas’). Implications of these results are discussed both at the level of functional architecture within the language production system and at the level of changes in language use.* PMID:21037930

  19. Development of a Stochastic Inversion Tool To Optimize Agreement Between The Observed And Predicted Seismic Response To CO2 Injection/Migration in the Weyburn-Midale Project

    SciTech Connect

    Ramirez, A L; Hao, Y; White, D; Carle, S; Dyer, K; Yang, X; Mcnab, W; Foxall, W; Johnson, J

    2009-12-02

    During Phase 1 of the Weyburn Project (2000-2004), 4D reflection seismic data were used to map CO{sub 2} migration within the Midale reservoir, while an extensive fluid sampling program documented the geochemical evolution triggered by CO{sub 2}-brine-oil-mineral interactions. The aim of this task (3b.11) is to exploit these existing seismic and geochemical data sets, augmented by CO{sub 2}/H{sub 2}O injection and HC/H{sub 2}O production data toward optimizing the reservoir model and thereby improving site characterization and dependent predictions of long-term CO{sub 2} storage in the Weyburn-Midale reservoir. Our initial project activities have concentrated on developing a stochastic inversion method that will identify reservoir models that optimize agreement between the observed and predicted seismic response. This report describes the technical approach we have followed, the data that supports it, and associated implementation activities. The report fulfills deliverable D1 in the project's statement of work. Future deliverables will describe the development of the stochastic inversion tool that uses geochemical data to optimize the reservoir model.

  20. The mitochondrial thioredoxin is required for liver development in zebrafish.

    PubMed

    Zhang, J; Cui, X; Wang, L; Liu, F; Jiang, T; Li, C; Li, D; Huang, M; Liao, S; Wang, J; Chen, J; Jia, H; He, J; Tang, Z; Yin, Z; Liu, M

    2014-01-01

    Thioredoxins (Trxs) are a class of small molecular redox proteins that play an important role in scavenging abnormally accumulated reactive oxygen species (ROS). Thioredoxin 2 (Trx2) is one member of this family located in mitochondria. Trx2 protects cells from increased oxidative stress and has anti-apoptosis function. Knockout of Trx2 in mice led to early embryonic lethality. However, the essential role of Trx2 during embryogenesis remains unclear. To further investigate the role of Trx2 during embryonic development, we performed Trx2 knockdown in zebrafish and investigated the regulation role of Trx2 during embryonic development. Our results indicate that Trx2 had a high expression in early zebrafish embryos and its knockdown in zebrafish led to defective liver development mainly due to increased hepatic cell death. The increased ROS and the imbalance of members of the Bcl-2 family were involved in cell death induced by Trx2 suppression in zebrafish. The dysregulation of Bax, puma and Bcl-xl promoted the reduction of mitochondrial trans-membrane potential and the mitochondria membrane permeabilization (MMP), which initiated the mitochondrial apoptosis pathway. Additionally, we found that the increase of relocated GAPDH in mitochondria may be another factor responsible for the mitochondrial catastrophe.

  1. Developing doctoral scientists for drug discovery: pluridimensional education required.

    PubMed

    Janero, David R

    2013-02-01

    Research universities continue to produce new scientists capable of generating knowledge with the potential to inform disease etiology and treatment. Mounting interest of doctoral-level experimental science students in therapeutics-related research careers is discordant with the widespread lack of direct drug-discovery and development experience, let alone commercialization success, among university faculty and administrators. Likewise, the archetypical publication- and grant-fueled, principal investigator (PI)-focused academic system ("PI-stan") risks commoditization of science students pursuing their doctorates as a labor source, rendering them ill-prepared for career options related to therapeutics innovation by marginalizing their development of "beyond-the-bench" professional skills foundational to modern drug-discovery campaigns and career fluency. To militate against professionalization deficits in doctoral drug-discovery researchers, the author--a scientist-administrator-consultant with decades of discovery research and development (R&D), business, and educator experience in commercial and university settings--posits a critical need for pluridimensionality in graduate education and mentorship that extends well beyond thesis-related scientific domains/laboratory techniques to instill transferable operational-intelligence, project/people-management, and communication competencies. Specific initiatives are advocated to help enhance the doctoral science student's market competitiveness, adaptability, and navigation of the significant research, commercial, and occupational challenges associated with contemporary preclinical drug-discovery R&D.

  2. Hematopoietic progenitors are required for proper development of coronary vasculature

    PubMed Central

    Lluri, Gentian; Huang, Vincent; Touma, Marlin; Liu, Xiaoqian; Harmon, Andrew W.; Nakano, Atsushi

    2015-01-01

    Rationale During embryogenesis, hematopoietic cells appear in the myocardium prior to the initiation of coronary formation. However, their role is unknown. Objective Here we investigate whether pre-existing hematopoietic cells are required for the formation of coronary vasculature. Methods and Results As a model of for hematopoietic cell deficient animals, we used Runx1 knockout embryos and Vav1-cre; R26-DTA embryos, latter of which genetically ablates 2/3 of CD45+ hematopoietic cells. Both Runx1 knockout embryos and Vav1-cre; R26-DTA embryos revealed disorganized, hypoplastic microvasculature of coronary vessels on section and whole-mount stainings. Furthermore, coronary explant experiments showed that the mouse heart explants from Runx1 and Vav1-cre; R26-DTA embryos exhibited impaired coronary formation ex vivo. Interestingly, in both models it appears that epicardial to mesenchymal transition is adversely affected in the absence of hematopoietic progenitors. Conclusion Hematopoietic cells are not merely passively transported via coronary vessel, but substantially involved in the induction of the coronary growth. Our findings suggest a novel mechanism of coronary growth. PMID:26241844

  3. Long bone development requires a threshold of Hox function.

    PubMed

    González-Martín, Ma Carmen; Mallo, Moises; Ros, Marian A

    2014-08-15

    The Hoxd(Del(11-13)) mutant is one of the animal models for human synpolydactyly, characterized by short and syndactylous digits. Here we have characterized in detail the cartilage and bone defects in these mutants. We report two distinct phenotypes: (i) a delay and change in pattern of chondrocyte maturation of metacarpals/metatarsals and (ii) formation of a poor and not centrally positioned primary ossification center in the proximal-intermediate phalanx. In the metacarpals of Hoxd(Del(11-13)) mutants, ossification occurs postnataly, in the absence of significant Ihh expression and without the establishment of growth plates, following patterns similar to those of short bones. The strong downregulation in Ihh expression is associated with a corresponding increase of the repressor form of Gli3. To evaluate the contribution of this alteration to the phenotype, we generated double Hoxd(Del(11-13));Gli3 homozygous mutants. Intriguingly, these double mutants showed a complete rescue of the phenotype in metatarsals but only partial phenotypic rescue in metacarpals. Our results support Hox genes being required in a dose-dependent manner for long bone cartilage maturation and suggest that and excess of Gli3R mediates a significant part of the Hoxd(Del(11-13)) chondrogenic phenotype.

  4. 46 CFR 298.38 - Partnership agreements and limited liability company agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false Partnership agreements and limited liability company... liability company agreements. Partnership and limited liability company agreements must be in form and...) Duration of the entity; (b) Adequate partnership or limited liability company funding requirements...

  5. 46 CFR 298.38 - Partnership agreements and limited liability company agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false Partnership agreements and limited liability company... liability company agreements. Partnership and limited liability company agreements must be in form and...) Duration of the entity; (b) Adequate partnership or limited liability company funding requirements...

  6. 46 CFR 298.38 - Partnership agreements and limited liability company agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Partnership agreements and limited liability company... liability company agreements. Partnership and limited liability company agreements must be in form and...) Duration of the entity; (b) Adequate partnership or limited liability company funding requirements...

  7. 46 CFR 298.38 - Partnership agreements and limited liability company agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Partnership agreements and limited liability company... liability company agreements. Partnership and limited liability company agreements must be in form and...) Duration of the entity; (b) Adequate partnership or limited liability company funding requirements...

  8. 49 CFR 605.15 - Content of agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL TRANSIT ADMINISTRATION... avoiding the requirements of this agreement, part 605 of the Federal Mass Transit Regulations, or section... avoiding the requirements of this agreement, part 605 of the Federal Transit Administration regulations...

  9. 49 CFR 605.15 - Content of agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL TRANSIT ADMINISTRATION... avoiding the requirements of this agreement, part 605 of the Federal Mass Transit Regulations, or section... avoiding the requirements of this agreement, part 605 of the Federal Transit Administration regulations...

  10. 49 CFR 605.15 - Content of agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL TRANSIT ADMINISTRATION... avoiding the requirements of this agreement, part 605 of the Federal Mass Transit Regulations, or section... avoiding the requirements of this agreement, part 605 of the Federal Transit Administration regulations...

  11. 49 CFR 605.15 - Content of agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL TRANSIT ADMINISTRATION... avoiding the requirements of this agreement, part 605 of the Federal Mass Transit Regulations, or section... avoiding the requirements of this agreement, part 605 of the Federal Transit Administration regulations...

  12. 49 CFR 605.15 - Content of agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL TRANSIT ADMINISTRATION... avoiding the requirements of this agreement, part 605 of the Federal Mass Transit Regulations, or section... avoiding the requirements of this agreement, part 605 of the Federal Transit Administration regulations...

  13. Why a true account of human development requires exemplar research.

    PubMed

    Damon, William; Colby, Anne

    2013-01-01

    This chapter uses moral psychology to illustrate why exemplar methods are essential for building a valid, complete understanding of key domains of human development. Social psychological, economic, and biological-evolutionary paradigms for studying morality rely on samples drawn from the general population. This research reveals a bleak picture of morality, highlighting its irrational, self-interested, externally controlled aspects. If the subjects in these studies are confused, pliable, or profit-maximizing, these studies conclude that people in general are morally irrational and self-interested. In contrast, studies that investigate morally exceptional individuals reveal a more thoughtful, ideal-driven, self-reflective, creative version of moral functioning. Any account that neglects this high-functioning segment of the range is seriously misleading and cannot provide the basis for aspiration or education.

  14. Nuclear Data for Medical Applications - Recent Developments and Future Requirements

    NASA Astrophysics Data System (ADS)

    Nichols, A. L.; Capote, R.

    2014-06-01

    Cancer treatment represents a major economic and medical issue because of the extensive incidence of the disease worldwide, with a particularly large rate of increase to be found in developing countries. Over the previous twenty years, the International Atomic Energy Agency (IAEA) has dedicated a series of investigations towards identifying and quantifying the production routes and decay characteristics of radioisotopes judged to be of existing and emerging importance in nuclear medicine and radiotherapy. Both the recommendations formulated during the course of these technical debates and the results of recently completed and on-going IAEA coordinated research projects are focused towards the successful evolution of improvements in nuclear data for medical applications throughout the early 21st century.

  15. Sexual Agreements among Gay Male Couples

    PubMed Central

    Hoff, Colleen H.; Beougher, Sean C.

    2009-01-01

    Many gay male couples make agreements about whether or not to permit sex with outside partners, yet little is known about the development and maintenance of these agreements, their impact on relationships, and whether they are an effective HIV prevention strategy. Using semi-structured, qualitative interviews, 39 gay male couples were asked about their sexual agreements and about other relationship dynamics that might affect their agreements. Analysis revealed a wide range of agreement types, all of which are presented along a continuum rather than as discrete categories. For couples with open agreements, most placed rules or conditions limiting when, where, how often, and with whom outside sex was permitted. Although motivations for having agreements varied, HIV prevention did not rank as a primary factor for any couple. Most couples had congruous agreements; however, a small number reported discrepancies which may increase HIV transmission risk. How couples handled breaks in their agreements also varied, depending on what condition was broken, whether it was disclosed, and the partner's reaction. Additional results include differences in agreement type and motivations for having an agreement based on couple serostatus. Overall, agreements benefited couples by providing boundaries for the relationship, supporting a non-heteronormative identity, and fulfilling the sexual needs of the couple. Future prevention efforts involving gay couples must address the range of agreement types and the meanings couples ascribe to them, in addition to tempering safety messages with the relationship issues that are important to and faced by gay couples. PMID:18686027

  16. Novel INHAT repressor (NIR) is required for early lymphocyte development.

    PubMed

    Ma, Chi A; Pusso, Antonia; Wu, Liming; Zhao, Yongge; Hoffmann, Victoria; Notarangelo, Luigi D; Fowlkes, B J; Jain, Ashish

    2014-09-23

    Novel inhibitor of histone acetyltransferase repressor (NIR) is a transcriptional corepressor with inhibitor of histone acetyltransferase activity and is a potent suppressor of p53. Although NIR deficiency in mice leads to early embryonic lethality, lymphoid-restricted deletion resulted in the absence of double-positive CD4(+)CD8(+) thymocytes, whereas bone-marrow-derived B cells were arrested at the B220(+)CD19(-) pro-B-cell stage. V(D)J recombination was preserved in NIR-deficient DN3 double-negative thymocytes, suggesting that NIR does not affect p53 function in response to physiologic DNA breaks. Nevertheless, the combined deficiency of NIR and p53 provided rescue of DN3L double-negative thymocytes and their further differentiation to double- and single-positive thymocytes, whereas B cells in the marrow further developed to the B220(+)CD19(+) pro-B-cell stage. Our results show that NIR cooperate with p53 to impose checkpoint for the generation of mature B and T lymphocytes.

  17. Tissue homogeneity requires inhibition of unequal gene silencing during development

    PubMed Central

    Le, Hai H.; Looney, Monika; Strauss, Benjamin; Bloodgood, Michael

    2016-01-01

    Multicellular organisms can generate and maintain homogenous populations of cells that make up individual tissues. However, cellular processes that can disrupt homogeneity and how organisms overcome such disruption are unknown. We found that ∼100-fold differences in expression from a repetitive DNA transgene can occur between intestinal cells in Caenorhabditis elegans. These differences are caused by gene silencing in some cells and are actively suppressed by parental and zygotic factors such as the conserved exonuclease ERI-1. If unsuppressed, silencing can spread between some cells in embryos but can be repeat specific and independent of other homologous loci within each cell. Silencing can persist through DNA replication and nuclear divisions, disrupting uniform gene expression in developed animals. Analysis at single-cell resolution suggests that differences between cells arise during early cell divisions upon unequal segregation of an initiator of silencing. Our results suggest that organisms with high repetitive DNA content, which include humans, could use similar developmental mechanisms to achieve and maintain tissue homogeneity. PMID:27458132

  18. 77 FR 25143 - Announcement of Meeting on “Developing Standard Requirements for Fatigue Performance of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-27

    ... Requirements for Fatigue Performance of Transvenous Cardiac Pacing and Defibrillation Leads'' AGENCY: National... on ``Developing Standard Requirements for Fatigue Performance of Transvenous Cardiac Pacing and... INFORMATION: The goal of the consortium will include determining methods that best measure the...

  19. Agreement in cardiovascular risk rating based on anthropometric parameters

    PubMed Central

    Dantas, Endilly Maria da Silva; Pinto, Cristiane Jordânia; Freitas, Rodrigo Pegado de Abreu; de Medeiros, Anna Cecília Queiroz

    2015-01-01

    Objective To investigate the agreement in evaluation of risk of developing cardiovascular diseases based on anthropometric parameters in young adults. Methods The study included 406 students, measuring weight, height, and waist and neck circumferences. Waist-to-height ratio and the conicity index. The kappa coefficient was used to assess agreement in risk classification for cardiovascular diseases. The positive and negative specific agreement values were calculated as well. The Pearson chi-square (χ2) test was used to assess associations between categorical variables (p<0.05). Results The majority of the parameters assessed (44%) showed slight (k=0.21 to 0.40) and/or poor agreement (k<0.20), with low values of negative specific agreement. The best agreement was observed between waist circumference and waist-to-height ratio both for the general population (k=0.88) and between sexes (k=0.93 to 0.86). There was a significant association (p<0.001) between the risk of cardiovascular diseases and females when using waist circumference and conicity index, and with males when using neck circumference. This resulted in a wide variation in the prevalence of cardiovascular disease risk (5.5%-36.5%), depending on the parameter and the sex that was assessed. Conclusion The results indicate variability in agreement in assessing risk for cardiovascular diseases, based on anthropometric parameters, and which also seems to be influenced by sex. Further studies in the Brazilian population are required to better understand this issue. PMID:26466060

  20. 26 CFR 1.1248-5 - Stock ownership requirements for less developed country corporations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Stock ownership requirements for less developed... Gains and Losses § 1.1248-5 Stock ownership requirements for less developed country corporations. (a... foreign corporation X, a less developed country corporation. On December 31, 1964, N recognizes gain...

  1. 24 CFR 972.115 - Relationship between required conversions and HOPE VI developments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... conversions and HOPE VI developments. 972.115 Section 972.115 Housing and Urban Development Regulations... Relationship between required conversions and HOPE VI developments. HUD actions to approve or deny proposed HOPE VI revitalization plans must be consistent with the requirements of this subpart....

  2. Latent Structure Agreement Analysis. A RAND Note.

    ERIC Educational Resources Information Center

    Uebersax, John; Grove, Will

    Methods of probability modeling to analyze rater agreement are described, emphasizing their basic similarities and viewing them as variants of a common methodology. Statistical techniques for analyzing agreement data are described to address questions such as how many opinions are required to make a medical diagnosis with necessary accuracy. Kappa…

  3. 7 CFR 247.4 - Agreements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.4 Agreements. (a) What agreements are... provide, or cause to be provided, nutrition education to participants, as required in § 247.18; (2)...

  4. 7 CFR 247.4 - Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.4 Agreements. (a) What agreements are... provide, or cause to be provided, nutrition education to participants, as required in § 247.18; (2)...

  5. 7 CFR 247.4 - Agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.4 Agreements. (a) What agreements are... provide, or cause to be provided, nutrition education to participants, as required in § 247.18; (2)...

  6. 7 CFR 247.4 - Agreements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.4 Agreements. (a) What agreements are... provide, or cause to be provided, nutrition education to participants, as required in § 247.18; (2)...

  7. 7 CFR 247.4 - Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.4 Agreements. (a) What agreements are... provide, or cause to be provided, nutrition education to participants, as required in § 247.18; (2)...

  8. 5 CFR 1655.12 - Loan agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 3 2012-01-01 2012-01-01 false Loan agreement. 1655.12 Section 1655.12 Administrative Personnel FEDERAL RETIREMENT THRIFT INVESTMENT BOARD LOAN PROGRAM § 1655.12 Loan agreement. (a) Upon determining that a loan application meets the requirements of this part, the TSP record...

  9. 5 CFR 1655.12 - Loan agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Loan agreement. 1655.12 Section 1655.12 Administrative Personnel FEDERAL RETIREMENT THRIFT INVESTMENT BOARD LOAN PROGRAM § 1655.12 Loan agreement. (a) Upon determining that a loan application meets the requirements of this part, the TSP record...

  10. Uniform administrative requirements for grants and agreements with institutions of higher education, hospitals and other non-profit organizations, and with commercial organizations, foreign governments, organizations under the jurisdiction of foreign governments, and international organizations--DOL. Final rule.

    PubMed

    1994-07-27

    The Department of Labor is issuing these regulations pursuant to the requirements of the Office of Management and Budget (OMB) Circular No. A-110 (Revised), which provides standards for obtaining consistency and uniformity among Federal agencies in the administration of grants and agreements with institutions of higher education, hospitals, and other non-profit organizations. This rule also applies to the Department of Labor's grants to commercial organizations, foreign governments, organizations under the jurisdiction of foreign governments and international organizations. OMB issued Circular A-110 in 1976 and, except for a minor revision in February 1987, the Circular remained unchanged until revised in 1993. To update the Circular, OMB established an interagency task force to review the Circular. The task force solicited suggestions for changes to the Circular from university groups, non-profit organizations and other interested parties and compared for consistency the provisions of similar provisions applied to State and local governments. The revised Circular and these regulations reflect the results of these efforts.

  11. The study on knowledge transferring incentive for information system requirement development

    SciTech Connect

    Li, Yang

    2015-03-10

    Information system requirement development is a process of users’ knowledge sharing and transferring. However the tacit requirements developing is a main problem during requirement development process, for the reason of difficult to encoding, express, and communicate. Knowledge fusion and corporate effort is needed to finding tacit requirements. Under this background, our paper try to find out the rule of effort dynamic evolutionary of software developer and user by building an evolutionary game model on the condition of incentive system. And in addition this paper provides an in depth discussion at the end of this paper.

  12. 40 CFR 256.62 - Requirements for public participation in State regulatory development.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Public Participation § 256.62 Requirements for public participation in State...

  13. 40 CFR 256.62 - Requirements for public participation in State regulatory development.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Public Participation § 256.62 Requirements for public participation in State...

  14. 40 CFR 256.62 - Requirements for public participation in State regulatory development.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Public Participation § 256.62 Requirements for public participation in State...

  15. 40 CFR 256.62 - Requirements for public participation in State regulatory development.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Public Participation § 256.62 Requirements for public participation in State...

  16. 40 CFR 256.62 - Requirements for public participation in State regulatory development.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Public Participation § 256.62 Requirements for public participation in State...

  17. Program management plan for development, demonstration, testing, and evaluation efforts associated with Oak Ridge Reservation`s Land Disposal Restrictions Federal Facility Compliance Agreement

    SciTech Connect

    Conley, T.B.

    1994-04-01

    This program management plan covers the development, demonstration, testing, and evaluation efforts necessary to identify treatment methods for all the waste listed in Appendix B of the ORR`s LDR/FFCA as well as any new wastes which meet Appendix B criteria. To successfully identify a treatment method, at least a proof-of-principle level of understanding must be obtained: that is, the candidate processes must be demonstrated as effective in treating the wastes to the LDR; however, an optimized process is not required. Where applicable and deemed necessary and where the budgets will support them, pilot-scale demonstrations will be pursued. The overall strategy being adopted in this program will be composed of the following activities: Scoping of the study; characterization; development and screening of alternatives; treatability investigations; and detailed analysis of alternatives.

  18. Review of the SOR Development Process and the Requirement for SOR-Spec Maker Software

    DTIC Science & Technology

    1998-04-01

    I DCIEM No. 98-CR- 55 REVIEW OF THE SOR DEVELOPMENT PROCESS AND THE REQUIREMENT FOR SOR-SPEC MAKER SOFTWARE by Michael P. Greenley and David...I Statement of Operational Requirement I I For I SOR-Spec Maker I Requirements Management Tool I I DRAFT I by I Mike Greenley April1998 I

  19. 22 CFR 19.7-4 - Form of agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Form of agreement. 19.7-4 Section 19.7-4... THE FOREIGN SERVICE RETIREMENT AND DISABILITY SYSTEM § 19.7-4 Form of agreement. (a) A spousal agreement is any legal agreement between the parties accepted by PER/ER/RET as meeting the requirements...

  20. 14 CFR 1274.213 - Distribution of cooperative agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Distribution of cooperative agreements... COOPERATIVE AGREEMENTS WITH COMMERCIAL FIRMS Pre-Award Requirements § 1274.213 Distribution of cooperative agreements. Copies of cooperative agreements and modifications will be provided to: payment office,...

  1. 14 CFR 1274.213 - Distribution of cooperative agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Distribution of cooperative agreements... COOPERATIVE AGREEMENTS WITH COMMERCIAL FIRMS Pre-Award Requirements § 1274.213 Distribution of cooperative agreements. Copies of cooperative agreements and modifications will be provided to: payment office,...

  2. 14 CFR § 1274.213 - Distribution of cooperative agreements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Distribution of cooperative agreements. Â... COOPERATIVE AGREEMENTS WITH COMMERCIAL FIRMS Pre-Award Requirements § 1274.213 Distribution of cooperative agreements. Copies of cooperative agreements and modifications will be provided to: payment office,...

  3. 14 CFR 1274.203 - Solicitations/cooperative agreement notices.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Solicitations/cooperative agreement notices... COOPERATIVE AGREEMENTS WITH COMMERCIAL FIRMS Pre-Award Requirements § 1274.203 Solicitations/cooperative agreement notices. (a) Agreement officers should use every effort to issue draft pre-award...

  4. 24 CFR 280.30 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Grant agreement. 280.30 Section 280... DEVELOPMENT GRANT PROGRAMS NEHEMIAH HOUSING OPPORTUNITY GRANTS PROGRAM Program Operation § 280.30 Grant agreement. (a) General. The recipient's responsibilities under NHOP will be incorporated in a...

  5. 24 CFR 280.30 - Grant agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Grant agreement. 280.30 Section 280... DEVELOPMENT GRANT PROGRAMS NEHEMIAH HOUSING OPPORTUNITY GRANTS PROGRAM Program Operation § 280.30 Grant agreement. (a) General. The recipient's responsibilities under NHOP will be incorporated in a...

  6. 34 CFR 675.35 - Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 3 2014-07-01 2014-07-01 false Agreement. 675.35 Section 675.35 Education Regulations..., DEPARTMENT OF EDUCATION FEDERAL WORK-STUDY PROGRAMS Job Location and Development Program § 675.35 Agreement... institution will not use program funds to locate and develop jobs at an eligible institution; (ii)...

  7. 34 CFR 675.35 - Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false Agreement. 675.35 Section 675.35 Education Regulations..., DEPARTMENT OF EDUCATION FEDERAL WORK-STUDY PROGRAMS Job Location and Development Program § 675.35 Agreement... institution will not use program funds to locate and develop jobs at an eligible institution; (ii)...

  8. 34 CFR 675.35 - Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false Agreement. 675.35 Section 675.35 Education Regulations..., DEPARTMENT OF EDUCATION FEDERAL WORK-STUDY PROGRAMS Job Location and Development Program § 675.35 Agreement... institution will not use program funds to locate and develop jobs at an eligible institution; (ii)...

  9. 34 CFR 675.35 - Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false Agreement. 675.35 Section 675.35 Education Regulations..., DEPARTMENT OF EDUCATION FEDERAL WORK-STUDY PROGRAMS Job Location and Development Program § 675.35 Agreement... institution will not use program funds to locate and develop jobs at an eligible institution; (ii)...

  10. 24 CFR 280.30 - Grant agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Grant agreement. 280.30 Section 280... DEVELOPMENT GRANT PROGRAMS NEHEMIAH HOUSING OPPORTUNITY GRANTS PROGRAM Program Operation § 280.30 Grant agreement. (a) General. The recipient's responsibilities under NHOP will be incorporated in a...

  11. 24 CFR 280.30 - Grant agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Grant agreement. 280.30 Section 280... DEVELOPMENT GRANT PROGRAMS NEHEMIAH HOUSING OPPORTUNITY GRANTS PROGRAM Program Operation § 280.30 Grant agreement. (a) General. The recipient's responsibilities under NHOP will be incorporated in a...

  12. Requirements Development Issues for Advanced Life Support Systems: Solid Waste Management

    NASA Technical Reports Server (NTRS)

    Levri, Julie A.; Fisher, John W.; Alazraki, Michael P.; Hogan, John A.

    2002-01-01

    Long duration missions pose substantial new challenges for solid waste management in Advanced Life Support (ALS) systems. These possibly include storing large volumes of waste material in a safe manner, rendering wastes stable or sterilized for extended periods of time, and/or processing wastes for recovery of vital resources. This is further complicated because future missions remain ill-defined with respect to waste stream quantity, composition and generation schedule. Without definitive knowledge of this information, development of requirements is hampered. Additionally, even if waste streams were well characterized, other operational and processing needs require clarification (e.g. resource recovery requirements, planetary protection constraints). Therefore, the development of solid waste management (SWM) subsystem requirements for long duration space missions is an inherently uncertain, complex and iterative process. The intent of this paper is to address some of the difficulties in writing requirements for missions that are not completely defined. This paper discusses an approach and motivation for ALS SWM requirements development, the characteristics of effective requirements, and the presence of those characteristics in requirements that are developed for uncertain missions. Associated drivers for life support system technological capability are also presented. A general means of requirements forecasting is discussed, including successive modification of requirements and the need to consider requirements integration among subsystems.

  13. 76 FR 61597 - Grants and Cooperative Agreements to State and Local Governments: DOT Amendments on Regulations...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ... and Agreements With Institutions of Higher Education, Hospitals and Other Non-Profit Organizations... Agreements to State and Local Governments; Grants and Agreements with Institutions of Higher Education... uniform administrative requirements for grants and agreements with Institutions of Higher...

  14. Requirements and Methods for Management Development Programmes in the Least Developed Countries in Africa.

    ERIC Educational Resources Information Center

    Perry, Chad

    1993-01-01

    Management development is essential for the economic development of least developed countries (LDCs) in Africa. The collectivist culture of LDCs necessitates development of behavior skills and attitudes and a cyclic, experiential learning approach. (SK)

  15. 13 CFR 303.7 - Requirements for Comprehensive Economic Development Strategies.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Economic Development Strategies. 303.7 Section 303.7 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT OF COMMERCE PLANNING INVESTMENTS AND COMPREHENSIVE ECONOMIC DEVELOPMENT STRATEGIES § 303.7 Requirements for Comprehensive Economic Development Strategies. (a) General. CEDS are...

  16. Canadian seismic agreement

    SciTech Connect

    Wetmiller, R.J.; Lyons, J.A.; Shannon, W.E.; Munro, P.S.; Thomas, J.T.; Andrew, M.D.; Lamontagne, M.; Wong, C.; Anglin, F.M.; Plouffe, M.; Adams, J.; Drysdale, J.A. . Geophysics Div.)

    1990-04-01

    During the period of this report, the contract resources were spent on operation and maintenance of the Eastern Canada Telemetred Network (ECTN), development of special purpose local network systems, servicing and maintenance of the strong-motion seismograph network in eastern Canada, operation of the Ottawa data lab and earthquake monitoring and reporting. Of special note in this period was the final completion of the Sudbury (SLTN) and Charlevoix (CLTN) local networks and the integration of their data processing and analysis requirements in the regular analysis stream for ECTN data. These networks now acquire high quality digital data for detailed analysis of seismic activity and source properties from these two areas, thus effectively doubling the amount of seismic data being received by the Ottawa data lab. 37 refs., 17 figs., 2 tabs.

  17. Designing eHealth that Matters via a Multidisciplinary Requirements Development Approach

    PubMed Central

    Wentzel, Jobke; Van Gemert-Pijnen, Julia EWC

    2013-01-01

    Background Requirements development is a crucial part of eHealth design. It entails all the activities devoted to requirements identification, the communication of requirements to other developers, and their evaluation. Currently, a requirements development approach geared towards the specifics of the eHealth domain is lacking. This is likely to result in a mismatch between the developed technology and end user characteristics, physical surroundings, and the organizational context of use. It also makes it hard to judge the quality of eHealth design, since it makes it difficult to gear evaluations of eHealth to the main goals it is supposed to serve. Objective In order to facilitate the creation of eHealth that matters, we present a practical, multidisciplinary requirements development approach which is embedded in a holistic design approach for eHealth (the Center for eHealth Research roadmap) that incorporates both human-centered design and business modeling. Methods Our requirements development approach consists of five phases. In the first, preparatory, phase the project team is composed and the overall goal(s) of the eHealth intervention are decided upon. Second, primary end users and other stakeholders are identified by means of audience segmentation techniques and our stakeholder identification method. Third, the designated context of use is mapped and end users are profiled by means of requirements elicitation methods (eg, interviews, focus groups, or observations). Fourth, stakeholder values and eHealth intervention requirements are distilled from data transcripts, which leads to phase five, in which requirements are communicated to other developers using a requirements notation template we developed specifically for the context of eHealth technologies. Results The end result of our requirements development approach for eHealth interventions is a design document which includes functional and non-functional requirements, a list of stakeholder values, and end

  18. 32 CFR Attachment 5 to Part 855 - Sample Temporary Agreement

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Agreement Letter of Agreement for Temporary Civil Aircraft Operations at Warbucks AFB, USA This letter of... Warbucks AFB, USA, (WAFB) for the period (date)through(date) Military requirements will take...

  19. An agreement coefficient for image comparison

    USGS Publications Warehouse

    Ji, L.; Gallo, K.

    2006-01-01

    Combination of datasets acquired from different sensor systems is necessary to construct a long time-series dataset for remotely sensed land-surface variables. Assessment of the agreement of the data derived from various sources is an important issue in understanding the data continuity through the time-series. Some traditional measures, including correlation coefficient, coefficient of determination, mean absolute error, and root mean square error, are not always optimal for evaluating the data agreement. For this reason, we developed a new agreement coefficient for comparing two different images. The agreement coefficient has the following properties: non-dimensional, bounded, symmetric, and distinguishable between systematic and unsystematic differences. The paper provides examples of agreement analyses for hypothetical data and actual remotely sensed data. The results demonstrate that the agreement coefficient does include the above properties, and therefore is a useful tool for image comparison. ?? 2006 American Society for Photogrammetry and Remote Sensing.

  20. Addressing the Barriers to Agile Development in the Department of Defense: Program Structure, Requirements, and Contracting

    DTIC Science & Technology

    2015-04-30

    with the IT Box requirements concept, and thus cannot take advantage of its flexibilities to enable Agile development. In addition, long contracting...place. Many DoD IT acquisition programs are unfamiliar with the IT Box requirements concept, and thus cannot take advantage of its flexibilities to...requirements, and contracting. The DoD can address these barriers by utilizing a proactively tailored Agile acquisition model, implementing an IT Box