Science.gov

Sample records for agreement required development

  1. 24 CFR 266.505 - Regulatory agreement requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Regulatory agreement requirements. 266.505 Section 266.505 Housing and Urban Development Regulations Relating to Housing and Urban... HOUSING AND URBAN DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND...

  2. Proposed Requirements-driven User-scenario Development Protocol for the Belmont Forum E-Infrastructure and Data Management Cooperative Research Agreement

    NASA Astrophysics Data System (ADS)

    Wee, B.; Car, N.; Percivall, G.; Allen, D.; Fitch, P. G.; Baumann, P.; Waldmann, H. C.

    2014-12-01

    The Belmont Forum E-Infrastructure and Data Management Cooperative Research Agreement (CRA) is designed to foster a global community to collaborate on e-infrastructure challenges. One of the deliverables is an implementation plan to address global data infrastructure interoperability challenges and align existing domestic and international capabilities. Work package three (WP3) of the CRA focuses on the harmonization of global data infrastructure for sharing environmental data. One of the subtasks under WP3 is the development of user scenarios that guide the development of applicable deliverables. This paper describes the proposed protocol for user scenario development. It enables the solicitation of user scenarios from a broad constituency, and exposes the mechanisms by which those solicitations are evaluated against requirements that map to the Belmont Challenge. The underlying principle of traceability forms the basis for a structured, requirements-driven approach resulting in work products amenable to trade-off analyses and objective prioritization. The protocol adopts the ISO Reference Model for Open Distributed Processing (RM-ODP) as a top level framework. User scenarios are developed within RM-ODP's "Enterprise Viewpoint". To harmonize with existing frameworks, the protocol utilizes the conceptual constructs of "scenarios", "use cases", "use case categories", and use case templates as adopted by recent GEOSS Architecture Implementation Project (AIP) deliverables and CSIRO's eReefs project. These constructs are encapsulated under the larger construct of "user scenarios". Once user scenarios are ranked by goodness-of-fit to the Belmont Challenge, secondary scoring metrics may be generated, like goodness-of-fit to FutureEarth science themes. The protocol also facilitates an assessment of the ease of implementing given user scenario using existing GEOSS AIP deliverables. In summary, the protocol results in a traceability graph that can be extended to coordinate

  3. 42 CFR 460.30 - Program agreement requirement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PACE Program Agreement § 460.30 Program agreement requirement. (a) A PACE organization...

  4. 42 CFR 460.30 - Program agreement requirement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PACE Program Agreement § 460.30 Program agreement requirement. (a) A PACE organization...

  5. 42 CFR 460.30 - Program agreement requirement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PACE Program Agreement § 460.30 Program agreement requirement. (a) A PACE organization...

  6. 42 CFR 460.30 - Program agreement requirement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PACE Program Agreement § 460.30 Program agreement requirement. (a) A PACE organization...

  7. 42 CFR 460.30 - Program agreement requirement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... (CONTINUED) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PACE Program Agreement § 460.30 Program agreement requirement. (a) A PACE organization...

  8. 42 CFR 442.12 - Provider agreement: General requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STANDARDS FOR PAYMENT TO NURSING FACILITIES AND INTERMEDIATE CARE FACILITIES FOR THE MENTALLY RETARDED Provider Agreements § 442.12 Provider agreement: General... to meet the civil rights requirements set forth in 45 CFR parts 80, 84, and 90....

  9. 40 CFR 35.6250 - Support agency Cooperative Agreement requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Support agency Cooperative Agreement requirements. 35.6250 Section 35.6250 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND... Tribes are exempt from the requirement of Intergovernmental Review in 40 CFR part 29.) An applicant...

  10. 40 CFR 35.6250 - Support agency Cooperative Agreement requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Support agency Cooperative Agreement requirements. 35.6250 Section 35.6250 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND... Tribes are exempt from the requirement of Intergovernmental Review in 40 CFR part 29.) An applicant...

  11. 40 CFR 35.6250 - Support agency Cooperative Agreement requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Support agency Cooperative Agreement requirements. 35.6250 Section 35.6250 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND... Tribes are exempt from the requirement of Intergovernmental Review in 40 CFR part 29.) An applicant...

  12. 40 CFR 35.6250 - Support agency Cooperative Agreement requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Support agency Cooperative Agreement requirements. 35.6250 Section 35.6250 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND... Tribes are exempt from the requirement of Intergovernmental Review in 40 CFR part 29.) An applicant...

  13. 40 CFR 35.6250 - Support agency Cooperative Agreement requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Support agency Cooperative Agreement requirements. 35.6250 Section 35.6250 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND... Tribes are exempt from the requirement of Intergovernmental Review in 40 CFR part 29.) An applicant...

  14. Cooperative research and development agreements at METC

    SciTech Connect

    Ludlow, J.C.; Jarr, L.A.; Anderson, R.J.

    1995-06-01

    The Federal Technology Transfer Act of 1986 (P.L. 99-502) provided a new mechanism for joint research between private parties and the Morgantown Energy Technology Center (METC). Joint projects under this law are called Cooperative Research And Development Agreements (CRADAs) and are simply agreements between METC and the private sector to work together on a mutually beneficial project. Of primary interest to METC is the development and deployment of: (1) clean, efficient power generation technologies, (2) technologies for the characterization and exploitation of the Nation`s natural gas resource, and (3) environmental remediation technologies.

  15. 24 CFR 1000.240 - When is a local cooperation agreement required for affordable housing activities?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false When is a local cooperation... ACTIVITIES Indian Housing Plan (IHP) § 1000.240 When is a local cooperation agreement required for affordable housing activities? The requirement for a local cooperation agreement applies only to rental and...

  16. 42 CFR 442.12 - Provider agreement: General requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STANDARDS FOR PAYMENT TO NURSING FACILITIES AND INTERMEDIATE CARE FACILITIES FOR INDIVIDUALS WITH INTELLECTUAL DISABILITIES Provider Agreements § 442.12... agency, if the facility fails to meet the civil rights requirements set forth in 45 CFR parts 80, 84,...

  17. 19 CFR 123.72 - Written agreement requirement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Written agreement requirement. 123.72 Section 123.72 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CUSTOMS RELATIONS WITH CANADA AND MEXICO Land Border Carrier Initiative Program §...

  18. 40 CFR 35.3550 - Specific capitalization grant agreement requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Drinking Water State Revolving Funds § 35.3550 Specific capitalization grant agreement requirements. (a) General. A State must agree to comply with this subpart, the general grant regulations at 40 CFR part 31, and specific conditions of the grant. A...

  19. 24 CFR 266.505 - Regulatory agreement requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... AUTHORITIES HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.505 Regulatory agreement requirements. (a) General. (1) The HFA... capital needs. (3) Maintain the project as affordable housing, as defined in § 266.5. (4) Continue to...

  20. 24 CFR 266.505 - Regulatory agreement requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AUTHORITIES HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.505 Regulatory agreement requirements. (a) General. (1) The HFA... capital needs. (3) Maintain the project as affordable housing, as defined in § 266.5. (4) Continue to...

  1. 24 CFR 266.505 - Regulatory agreement requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... AUTHORITIES HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.505 Regulatory agreement requirements. (a) General. (1) The HFA... capital needs. (3) Maintain the project as affordable housing, as defined in § 266.5. (4) Continue to...

  2. 24 CFR 266.505 - Regulatory agreement requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... AUTHORITIES HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.505 Regulatory agreement requirements. (a) General. (1) The HFA... capital needs. (3) Maintain the project as affordable housing, as defined in § 266.5. (4) Continue to...

  3. 40 CFR 35.3135 - Specific capitalization grant agreement requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Specific capitalization grant agreement requirements. 35.3135 Section 35.3135 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE State Water Pollution Control Revolving Funds § 35.3135 Specific capitalization...

  4. 22 CFR 124.7 - Information required in all manufacturing license agreements and technical assistance agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... defense articles to be exported, including any test and support equipment or advanced materials. They.... Only defense articles listed in the agreement will be eligible for export under the exemption in §...

  5. Development and Validation of the Sexual Agreement Investment Scale

    PubMed Central

    Neilands, Torsten B.; Chakravarty, Deepalika; Darbes, Lynae A.; Beougher, Sean C.; Hoff, Colleen C.

    2009-01-01

    Introduction Sexual agreements are ubiquitous among gay men. Lower levels of investment in these agreements may be associated with breaking them or engaging in risky sexual behavior. We developed a scale to measure agreement investment levels among gay men. Methods We analyzed qualitative data from 78 gay men in committed relationships to inform item development, followed by quantitative analyses of two larger samples (n=380; n=1001) to assess construct, convergent, and discriminant validity. Results The Sexual Agreement Investment Scale (SAIS) is a psychometrically sound measure of level of the investment in sexual agreements among gay men in relationships. Men with higher agreement investment were less likely to break agreements and to engage in unprotected intercourse with outside partners. Discussion The SAIS can be used to measure investment in sexual agreements and its impact on sexual behavior in a wide variety of settings, including research on relationships, sexuality, couples therapy, and HIV-prevention. PMID:19396645

  6. 20 CFR 603.10 - What are the requirements for agreements?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... INFORMATION Confidentiality and Disclosure Requirements § 603.10 What are the requirements for agreements? (a) Requirements. (1) For disclosures of confidential UC information under § 603.5(d)(2) (to a third party (other... agreement with any agency or entity requesting disclosure(s) of such information. The agreement must...

  7. Information System Requirements Determination: Factors Impeding Stakeholders from Reaching Common Understandings and Agreements on Requirements

    ERIC Educational Resources Information Center

    Gissel, Richard L.

    2010-01-01

    Information system implementations require developers to first know what they must create and then determine how best to create it. The requirements determination phase of the system development life cycle typically determines what functions a system must perform and how well it must accomplish required functions. Implementation success depends on…

  8. 22 CFR 124.9 - Additional clauses required only in manufacturing license agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... manufacturing license agreements. 124.9 Section 124.9 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL... Additional clauses required only in manufacturing license agreements. (a) Clauses for all manufacturing license agreements. The following clauses must be included only in manufacturing license agreements:...

  9. 22 CFR 124.9 - Additional clauses required only in manufacturing license agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... manufacturing license agreements. 124.9 Section 124.9 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL... Additional clauses required only in manufacturing license agreements. (a) Clauses for all manufacturing license agreements. The following clauses must be included only in manufacturing license agreements:...

  10. 22 CFR 124.9 - Additional clauses required only in manufacturing license agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... manufacturing license agreements. 124.9 Section 124.9 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL... Additional clauses required only in manufacturing license agreements. (a) Clauses for all manufacturing license agreements. The following clauses must be included only in manufacturing license agreements:...

  11. 22 CFR 124.9 - Additional clauses required only in manufacturing license agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... manufacturing license agreements. 124.9 Section 124.9 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL... Additional clauses required only in manufacturing license agreements. (a) Clauses for all manufacturing license agreements. The following clauses must be included only in manufacturing license agreements:...

  12. 10 CFR 150.17a - Compliance with requirements of US/IAEA Safeguards Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Compliance with requirements of US/IAEA Safeguards... Authority in Agreement States § 150.17a Compliance with requirements of US/IAEA Safeguards Agreement. (a... shall take other action as may be necessary to implement the US/IAEA Safeguards Agreement, as...

  13. FEDERAL FACILITY COMPLIANCE AGREEMENT (FFCA) STACK ISOLATION PROJECT FUNCTIONS & REQUIREMENTS

    SciTech Connect

    TRANBARGER, R.K.

    2003-12-16

    This document delineates the functions and requirements for the FFCA Stack Isolation Project for the 244-A, 244-BX, 244-5, and 244-TX DCRTs. The isolation of each ventilation system and stack includes the electrical, instrumentation, and mechanical isolation of the ventilation system and the installation of primary and annulus breather filters to provide passive ventilation to meet the FFCA requirements.

  14. Co-Development Agreements | NCI Technology Transfer Center | TTC

    Cancer.gov

    The National Cancer Institute's TTC uses three different co-development agreements to help industry and academia interact and partner with National Institutes of Health laboratories and scientists to support technology development activities.

  15. Guidebook to Developing a Collaborative Partnership Written Agreement.

    ERIC Educational Resources Information Center

    Illinois State Dept. of Human Services, East St. Louis. Head Start State Collaboration Office.

    As programs serving young children and their families increasingly work together to provide services, written agreements or contracts become more important in clarifying the roles of each partner in the collaboration. This document provides guidance in developing written agreements between Head Start programs and other programs or agencies. The…

  16. 42 CFR 442.12 - Provider agreement: General requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... agency, if the facility fails to meet the civil rights requirements set forth in 45 CFR parts 80, 84, and... SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STANDARDS FOR PAYMENT TO NURSING FACILITIES AND... nursing facility services nor make Medicaid payments to a facility for those services unless the...

  17. 42 CFR 442.12 - Provider agreement: General requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... agency, if the facility fails to meet the civil rights requirements set forth in 45 CFR parts 80, 84, and... SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STANDARDS FOR PAYMENT TO NURSING FACILITIES AND... nursing facility services nor make Medicaid payments to a facility for those services unless the...

  18. 40 CFR 35.3550 - Specific capitalization grant agreement requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... subpart, the general grant regulations at 40 CFR part 31, and specific conditions of the grant. A State... match requirements associated with subsequent capitalization grants. (h) Provide match for State program... with all applicable Federal cross-cutting authorities. (p) Comply with provisions to avoid...

  19. 48 CFR 22.504 - General requirements for project labor agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... project labor agreements. 22.504 Section 22.504 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Use of Project Labor Agreements for Federal Construction Projects 22.504 General requirements for project labor agreements....

  20. 48 CFR 22.504 - General requirements for project labor agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... project labor agreements. 22.504 Section 22.504 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Use of Project Labor Agreements for Federal Construction Projects 22.504 General requirements for project labor agreements....

  1. 48 CFR 22.504 - General requirements for project labor agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... project labor agreements. 22.504 Section 22.504 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Use of Project Labor Agreements for Federal Construction Projects 22.504 General requirements for project labor agreements....

  2. 48 CFR 22.504 - General requirements for project labor agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... project labor agreements. 22.504 Section 22.504 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Use of Project Labor Agreements for Federal Construction Projects 22.504 General requirements for project labor agreements....

  3. 26 CFR 1.367(a)-8 - Gain recognition agreement requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 4 2011-04-01 2011-04-01 false Gain recognition agreement requirements. 1.367(a)-8 Section 1.367(a)-8 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Effects on Corporation § 1.367(a)-8 Gain recognition agreement requirements. (a) Scope. This section...

  4. 26 CFR 1.367(a)-8 - Gain recognition agreement requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 4 2014-04-01 2014-04-01 false Gain recognition agreement requirements. 1.367(a)-8 Section 1.367(a)-8 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Effects on Corporation § 1.367(a)-8 Gain recognition agreement requirements. (a) Scope....

  5. 26 CFR 1.367(a)-8 - Gain recognition agreement requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 4 2012-04-01 2012-04-01 false Gain recognition agreement requirements. 1.367(a)-8 Section 1.367(a)-8 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (Continued) Effects on Corporation § 1.367(a)-8 Gain recognition agreement requirements. (a) Scope....

  6. 26 CFR 1.367(a)-8 - Gain recognition agreement requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 4 2013-04-01 2013-04-01 false Gain recognition agreement requirements. 1.367(a)-8 Section 1.367(a)-8 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Effects on Corporation § 1.367(a)-8 Gain recognition agreement requirements. (a) Scope....

  7. 47 CFR 80.161 - Operator requirements of the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Operator requirements of the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Operator Requirements Ship Station Operator Requirements § 80.161 Operator requirements of the Great Lakes Radio Agreement. Each ship subject to the...

  8. 47 CFR 80.161 - Operator requirements of the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Operator requirements of the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Operator Requirements Ship Station Operator Requirements § 80.161 Operator requirements of the Great Lakes Radio Agreement. Each ship subject to the...

  9. 47 CFR 80.161 - Operator requirements of the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Operator requirements of the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Operator Requirements Ship Station Operator Requirements § 80.161 Operator requirements of the Great Lakes Radio Agreement. Each ship subject to the...

  10. 47 CFR 80.161 - Operator requirements of the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Operator requirements of the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Operator Requirements Ship Station Operator Requirements § 80.161 Operator requirements of the Great Lakes Radio Agreement. Each ship subject to the...

  11. 47 CFR 80.161 - Operator requirements of the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Operator requirements of the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Operator Requirements Ship Station Operator Requirements § 80.161 Operator requirements of the Great Lakes Radio Agreement. Each ship subject to the...

  12. Developing country finance in a post-2020 global climate agreement

    NASA Astrophysics Data System (ADS)

    Hannam, Phillip M.; Liao, Zhenliang; Davis, Steven J.; Oppenheimer, Michael

    2015-11-01

    A central task for negotiators of the post-2020 global climate agreement is to construct a finance regime that supports low-carbon development in developing economies. As power sector investments between developing countries grow, the climate finance regime should incentivize the decarbonization of these major sources of finance by integrating them as a complement to the commitments of developed nations. The emergence of the Asian Infrastructure Investment Bank, South-South Cooperation Fund and other nascent institutions reveal the fissures that exist in rules and norms surrounding international finance in the power sector. Structuring the climate agreement in Paris to credit qualified finance from the developing world could have several advantages, including: (1) encouraging low-carbon cooperation between developing countries; (2) incentivizing emerging investors to prefer low-carbon investments; and (3) enabling more cost-effective attainment of national and global climate objectives. Failure to coordinate on standards now could hinder low-carbon development in the decades to come.

  13. FY2011 Progress Report: Agreement 8697 - NOx Sensor Development

    SciTech Connect

    Woo, L Y; Glass, R S

    2011-11-01

    Objectives are: (1) Develop an inexpensive, rapid-response, high-sensitivity and selective electrochemical sensor for oxides of nitrogen (NO{sub x}) for compression-ignition, direct-injection (CIDI) OBD II systems; (2) Explore and characterize novel, effective sensing methodologies based on impedance measurements and designs and manufacturing methods that are compatible with mass fabrication; and (3) Collaborate with industry in order to (ultimately) transfer the technology to a supplier for commercialization. Approach used is: (1) Use an ionic (O{sup 2-}) conducting ceramic as a solid electrolyte and metal or metal-oxide electrodes; (2) Correlate NO{sub x} concentration with changes in cell impedance; (3) Evaluate sensing mechanisms and aging effects on long-term performance using electrochemical techniques; and (4) Collaborate with Ford Research Center to optimize sensor performance and perform dynamometer and on-vehicle testing. Work in FY2011 focused on using an algorithm developed in FY2010 in a simplified strategy to demonstrate how data from controlled laboratory evaluation could be applied to data from real-world engine testing. The performance of a Au wire prototype sensor was evaluated in the laboratory with controlled gas compositions and in dynamometer testing with diesel exhaust. The laboratory evaluation indicated a nonlinear dependence of the NO{sub x} and O{sub 2} sensitivity with concentration. For both NO{sub x} and O{sub 2}, the prototype sensor had higher sensitivity at concentrations less than {approx}20 ppm and {approx}7%, respectively, compared to lower NO{sub x} and O{sub 2} sensitivity at concentrations greater than {approx}50 ppm and {approx}10.5%, respectively. Results in dynamometer diesel exhaust generally agreed with the laboratory results. Diesel exhaust after-treatment systems will likely require detection levels less than {approx}20 ppm in order to meet emission regulations. The relevant mathematical expressions for sensitivity in

  14. 20 CFR 410.629d - Expedited appeals process; agreement requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Expedited appeals process; agreement... HEALTH AND SAFETY ACT OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Determinations of Disability, Other... appeals process; agreement requirements. (a)(1) An authorized representative of the Commissioner shall,...

  15. 14 CFR 203.3 - Filing requirements for adherence to Montreal Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Montreal Agreement. 203.3 Section 203.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF... DEFENSES § 203.3 Filing requirements for adherence to Montreal Agreement. All direct U.S. and foreign air... liability limitations of the Warsaw Convention and Hague Protocol approved by CAB Order E-23680, dated...

  16. 14 CFR 203.3 - Filing requirements for adherence to Montreal Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Montreal Agreement. 203.3 Section 203.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF... DEFENSES § 203.3 Filing requirements for adherence to Montreal Agreement. All direct U.S. and foreign air... liability limitations of the Warsaw Convention and Hague Protocol approved by CAB Order E-23680, dated...

  17. 14 CFR 203.3 - Filing requirements for adherence to Montreal Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Montreal Agreement. 203.3 Section 203.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF... DEFENSES § 203.3 Filing requirements for adherence to Montreal Agreement. All direct U.S. and foreign air... liability limitations of the Warsaw Convention and Hague Protocol approved by CAB Order E-23680, dated...

  18. 14 CFR 203.3 - Filing requirements for adherence to Montreal Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Montreal Agreement. 203.3 Section 203.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF... DEFENSES § 203.3 Filing requirements for adherence to Montreal Agreement. All direct U.S. and foreign air... liability limitations of the Warsaw Convention and Hague Protocol approved by CAB Order E-23680, dated...

  19. 14 CFR 203.3 - Filing requirements for adherence to Montreal Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Montreal Agreement. 203.3 Section 203.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF... DEFENSES § 203.3 Filing requirements for adherence to Montreal Agreement. All direct U.S. and foreign air... liability limitations of the Warsaw Convention and Hague Protocol approved by CAB Order E-23680, dated...

  20. 43 CFR 2812.3-4 - Where no road use agreement is required.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Where no road use agreement is required. 2812.3-4 Section 2812.3-4 Public Lands: Interior Regulations Relating to Public Lands (Continued... LOGGING ROADS Over O. and C. and Coos Bay Revested Lands § 2812.3-4 Where no road use agreement...

  1. 43 CFR 2812.3-4 - Where no road use agreement is required.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Where no road use agreement is required. 2812.3-4 Section 2812.3-4 Public Lands: Interior Regulations Relating to Public Lands (Continued... LOGGING ROADS Over O. and C. and Coos Bay Revested Lands § 2812.3-4 Where no road use agreement...

  2. 43 CFR 2812.3-4 - Where no road use agreement is required.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Where no road use agreement is required. 2812.3-4 Section 2812.3-4 Public Lands: Interior Regulations Relating to Public Lands (Continued... LOGGING ROADS Over O. and C. and Coos Bay Revested Lands § 2812.3-4 Where no road use agreement...

  3. 43 CFR 2812.3-4 - Where no road use agreement is required.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Where no road use agreement is required. 2812.3-4 Section 2812.3-4 Public Lands: Interior Regulations Relating to Public Lands (Continued... LOGGING ROADS Over O. and C. and Coos Bay Revested Lands § 2812.3-4 Where no road use agreement...

  4. 10 CFR 150.31 - Requirements for Agreement State regulation of byproduct material.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... with the requirements in appendix A of 10 CFR part 40 of this chapter to the maximum extent practicable... material, an Agreement State shall require: (1) Compliance with requirements in appendix A of 10 CFR part... in appendix A of 10 CFR part 40 of this chapter adopted and enforced by the Commission for the...

  5. 10 CFR 150.31 - Requirements for Agreement State regulation of byproduct material.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... with the requirements in appendix A of 10 CFR part 40 of this chapter to the maximum extent practicable... material, an Agreement State shall require: (1) Compliance with requirements in appendix A of 10 CFR part... in appendix A of 10 CFR part 40 of this chapter adopted and enforced by the Commission for the...

  6. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Watch required by the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  7. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Watch required by the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  8. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Watch required by the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  9. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Watch required by the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  10. 47 CFR 80.308 - Watch required by the Great Lakes Radio Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Watch required by the Great Lakes Radio... SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Safety Watch Requirements and Procedures Ship Station Safety Watches § 80.308 Watch required by the Great Lakes Radio Agreement. (a) Each ship of...

  11. 10 CFR 150.31 - Requirements for Agreement State regulation of byproduct material.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... with the requirements in appendix A of 10 CFR part 40 of this chapter to the maximum extent practicable... material, an Agreement State shall require: (1) Compliance with requirements in appendix A of 10 CFR part... in appendix A of 10 CFR part 40 of this chapter adopted and enforced by the Commission for the...

  12. 10 CFR 150.31 - Requirements for Agreement State regulation of byproduct material.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... with the requirements in appendix A of 10 CFR part 40 of this chapter to the maximum extent practicable... material, an Agreement State shall require: (1) Compliance with requirements in appendix A of 10 CFR part... in appendix A of 10 CFR part 40 of this chapter adopted and enforced by the Commission for the...

  13. 10 CFR 150.31 - Requirements for Agreement State regulation of byproduct material.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... with the requirements in appendix A of 10 CFR part 40 of this chapter to the maximum extent practicable... material, an Agreement State shall require: (1) Compliance with requirements in appendix A of 10 CFR part... in appendix A of 10 CFR part 40 of this chapter adopted and enforced by the Commission for the...

  14. Reduction of Conflicts in Mining Development Using "Good Neighbor Agreements"

    NASA Astrophysics Data System (ADS)

    Masaitis, A.

    2013-05-01

    New environmental and social challenges for the mining industry in both developed and developing countries show the obvious need to implement "responsible" mining practices that include improved community involvement. Good Neighbor Agreements (GNA's) are a relatively new mechanism for improving communication and trust between a mining company and the community. The focus of a GNA will be to provide a written and enforceable agreement, negotiated between the concerned public and the respective mining company to respond to concerns from the public, and also provide a mechanism for conflict resolution, when there is mutual benefit to maintain a working relationship. Development of GNA's, a recently evolving process that promotes environmentally sound relationships between mines and the surrounding communities. Modify and apply the resulting GNA formulas to the developing countries and countries with transitional economies. This is particularly important for countries that have poorly functioning regulatory systems that cannot guarantee a healthy and safe environment for the communities. The fundamental questions addressed by this research. 1. This is a three-year research project started in August 2012 at the University of Nevada, Reno (UNR) to develop a Good Neighbor Agreements standards as well as to investigate the details of mine development. 2. Identify spheres of possible cooperation between mining companies, government organizations, and the Non-Governmental Organizations (NGO's). Use this cooperation to develop international standards for the GNA, to promote exchange of environmental information, and exchange of successful environmental, health, and safety practices between mining operations from different countries. Discussion: The Good Neighbor Agreement currently evolving will address the following: 1. Provide an economically viable mechanism for developing a partnership between mining operations and the local communities that will increase mining industry

  15. 25 CFR 84.008 - What is the effect of the Secretary's disapproval of a contract or agreement that requires...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... contract or agreement that requires Secretarial approval under this part? 84.008 Section 84.008 Indians... that requires Secretarial approval under this part? If the Secretary disapproves a contract or agreement that requires Secretarial approval under this part, the contract or agreement is invalid as...

  16. 25 CFR 84.008 - What is the effect of the Secretary's disapproval of a contract or agreement that requires...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... contract or agreement that requires Secretarial approval under this part? 84.008 Section 84.008 Indians... that requires Secretarial approval under this part? If the Secretary disapproves a contract or agreement that requires Secretarial approval under this part, the contract or agreement is invalid as...

  17. 25 CFR 84.008 - What is the effect of the Secretary's disapproval of a contract or agreement that requires...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... contract or agreement that requires Secretarial approval under this part? 84.008 Section 84.008 Indians... that requires Secretarial approval under this part? If the Secretary disapproves a contract or agreement that requires Secretarial approval under this part, the contract or agreement is invalid as...

  18. 25 CFR 84.008 - What is the effect of the Secretary's disapproval of a contract or agreement that requires...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... contract or agreement that requires Secretarial approval under this part? 84.008 Section 84.008 Indians... that requires Secretarial approval under this part? If the Secretary disapproves a contract or agreement that requires Secretarial approval under this part, the contract or agreement is invalid as...

  19. 25 CFR 84.008 - What is the effect of the Secretary's disapproval of a contract or agreement that requires...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... contract or agreement that requires Secretarial approval under this part? 84.008 Section 84.008 Indians... that requires Secretarial approval under this part? If the Secretary disapproves a contract or agreement that requires Secretarial approval under this part, the contract or agreement is invalid as...

  20. 26 CFR 1.367(a)-8 - Gain recognition agreement requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 4 2010-04-01 2010-04-01 false Gain recognition agreement requirements. 1.367(a)-8 Section 1.367(a)-8 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Effects on Corporation § 1.367(a)-8 Gain...

  1. 20 CFR 603.10 - What are the requirements for agreements?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false What are the requirements for agreements? 603.10 Section 603.10 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR FEDERAL-STATE UNEMPLOYMENT COMPENSATION (UC) PROGRAM; CONFIDENTIALITY AND DISCLOSURE OF STATE...

  2. 40 CFR Appendix C-1 to Subpart E... - Required Provisions-Consulting Engineering Agreements

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... violation of section 204(a)(6) of the Clean Water Act. This statute requires that no specification for bids.... This agreement which covers grant-eligible work is subject to regulations contained in 40 CFR 35.936...'s control. Where innovative processes or techniques (see 40 CFR 35.908) are recommended by...

  3. 40 CFR Appendix C-1 to Subpart E... - Required Provisions-Consulting Engineering Agreements

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... violation of section 204(a)(6) of the Clean Water Act. This statute requires that no specification for bids.... This agreement which covers grant-eligible work is subject to regulations contained in 40 CFR 35.936...'s control. Where innovative processes or techniques (see 40 CFR 35.908) are recommended by...

  4. 26 CFR 36.3121(l)(10)-1 - Requirements in respect of liability under agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... agreement. 36.3121(l)(10)-1 Section 36.3121(l)(10)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT... OF EMPLOYEES OF FOREIGN SUBSIDIARIES § 36.3121(l)(10)-1 Requirements in respect of liability under... provided in § 36.3121(l)(1)-1....

  5. 26 CFR 36.3121(l)(10)-1 - Requirements in respect of liability under agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... agreement. 36.3121(l)(10)-1 Section 36.3121(l)(10)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT... OF EMPLOYEES OF FOREIGN SUBSIDIARIES § 36.3121(l)(10)-1 Requirements in respect of liability under... provided in § 36.3121(l)(1)-1....

  6. 26 CFR 36.3121(l)(10)-1 - Requirements in respect of liability under agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... agreement. 36.3121(l)(10)-1 Section 36.3121(l)(10)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT... OF EMPLOYEES OF FOREIGN SUBSIDIARIES § 36.3121(l)(10)-1 Requirements in respect of liability under... provided in § 36.3121(l)(1)-1....

  7. 26 CFR 36.3121(l)(10)-1 - Requirements in respect of liability under agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... agreement. 36.3121(l)(10)-1 Section 36.3121(l)(10)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT... OF EMPLOYEES OF FOREIGN SUBSIDIARIES § 36.3121(l)(10)-1 Requirements in respect of liability under... provided in § 36.3121(l)(1)-1....

  8. 26 CFR 36.3121(l)(10)-1 - Requirements in respect of liability under agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... agreement. 36.3121(l)(10)-1 Section 36.3121(l)(10)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT... OF EMPLOYEES OF FOREIGN SUBSIDIARIES § 36.3121(l)(10)-1 Requirements in respect of liability under... provided in § 36.3121(l)(1)-1....

  9. 48 CFR 801.602-74 - Review requirements for an interagency agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION REGULATION SYSTEM Career Development... Federal agency to be awarded under authority of the Economy Act, regardless of dollar value. For VA... facility interagency agreement with another Federal agency awarded under authority of the Economy...

  10. 76 FR 78290 - Cooperative Research and Development Agreement: Usage of Biodiesel Fuel Blends Within Marine...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-16

    ... Register (73 FR 3316). Cooperative Research and Development Agreements Cooperative Research and Development... SECURITY Coast Guard Cooperative Research and Development Agreement: Usage of Biodiesel Fuel Blends Within... technology enhancements, performance, costs, and other issues associated with using biodiesel fuel blends...

  11. 25 CFR 84.003 - What types of contracts and agreements require Secretarial approval under this part?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true What types of contracts and agreements require Secretarial... and agreements require Secretarial approval under this part? Unless otherwise provided in this part... more years require Secretarial approval under this part....

  12. 25 CFR 84.006 - Under what circumstances will the Secretary disapprove a contract or agreement that requires...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... contract or agreement that requires Secretarial approval under this part? 84.006 Section 84.006 Indians... that requires Secretarial approval under this part? (a) The Secretary will disapprove a contract or agreement that requires Secretarial approval under this part if the Secretary determines that such...

  13. 25 CFR 84.006 - Under what circumstances will the Secretary disapprove a contract or agreement that requires...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... contract or agreement that requires Secretarial approval under this part? 84.006 Section 84.006 Indians... that requires Secretarial approval under this part? (a) The Secretary will disapprove a contract or agreement that requires Secretarial approval under this part if the Secretary determines that such...

  14. 25 CFR 84.006 - Under what circumstances will the Secretary disapprove a contract or agreement that requires...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... contract or agreement that requires Secretarial approval under this part? 84.006 Section 84.006 Indians... that requires Secretarial approval under this part? (a) The Secretary will disapprove a contract or agreement that requires Secretarial approval under this part if the Secretary determines that such...

  15. European Union's public fishing access agreements in developing countries.

    PubMed

    Le Manach, Frédéric; Chaboud, Christian; Copeland, Duncan; Cury, Philippe; Gascuel, Didier; Kleisner, Kristin M; Standing, André; Sumaila, U Rashid; Zeller, Dirk; Pauly, Daniel

    2013-01-01

    The imperative to increase seafood supply while dealing with its overfished local stocks has pushed the European Union (EU) and its Member States to fish in the Exclusive Economic Zones of other countries through various types of fishing agreements for decades. Although European public fishing agreements are commented on regularly and considered to be transparent, this is the first global and historical study on the fee regime that governs them. We find that the EU has subsidized these agreements at an average of 75% of their cost (financial contribution agreed upon in the agreements), while private European business interests paid the equivalent of 1.5% of the value of the fish that was eventually landed. This raises questions of fisheries benefit-sharing and resource-use equity that the EU has the potential to address during the nearly completed reform of its Common Fisheries Policy. PMID:24312191

  16. 20 CFR 411.410 - Does each referral from an EN to a State VR agency require its own agreement?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Does each referral from an EN to a State VR...' Participation Agreements Between Employment Networks and State Vr Agencies § 411.410 Does each referral from an EN to a State VR agency require its own agreement? No. The agreements between ENs and State...

  17. 25 CFR 84.006 - Under what circumstances will the Secretary disapprove a contract or agreement that requires...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... contract or agreement that requires Secretarial approval under this part? 84.006 Section 84.006 Indians...-CONTRACT APPROVALS § 84.006 Under what circumstances will the Secretary disapprove a contract or agreement that requires Secretarial approval under this part? (a) The Secretary will disapprove a contract...

  18. Planetary rover technology development requirements

    NASA Technical Reports Server (NTRS)

    Bedard, Roger J., Jr.; Muirhead, Brian K.; Montemerlo, Melvin D.; Hirschbein, Murray S.

    1989-01-01

    Planetary surface (including lunar) mobility and sampling capability is required to support proposed future National Aeronautics and Space Administration (NASA) solar system exploration missions. The NASA Office of Aeronautics and Space Technology (OAST) is addressing some of these technology needs in its base research and development program, the Civil Space Technology Initiative (CSTI) and a new technology initiative entitled Pathfinder. The Pathfinder Planetary Rover (PPR) and Sample Acquisition, Analysis and Preservation (SAAP) programs will develop and validate the technologies needed to enable both robotic and piloted rovers on various planetary surfaces. The technology requirements for a planetary roving vehicle and the development plans of the PPR and SAAP programs are discussed.

  19. 40 CFR Appendix A to Subpart E of... - Schedule for Developing Consent Agreements and Test Rules

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Agreements and Test Rules A Appendix A to Subpart E of Part 790 Protection of Environment ENVIRONMENTAL... AGREEMENTS AND TEST RULES Exemptions From Test Rules Pt. 790, Subpt. E, App. A Appendix A to Subpart E of... required under section 4(a) of TSCA but agreement cannot be reached in timely manner on a consent...

  20. 43 CFR 3137.40 - What initial development obligations must I define in a unit agreement?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... I define in a unit agreement? 3137.40 Section 3137.40 Public Lands: Interior Regulations Relating to... Reserve-Alaska Development § 3137.40 What initial development obligations must I define in a unit agreement? Your unit agreement must define— (a) The number of wells you anticipate will be necessary...

  1. 20 CFR 411.410 - Does each referral from an EN to a State VR agency require its own agreement?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Does each referral from an EN to a State VR agency require its own agreement? 411.410 Section 411.410 Employees' Benefits SOCIAL SECURITY...' Participation Agreements Between Employment Networks and State Vr Agencies § 411.410 Does each referral from...

  2. 20 CFR 411.410 - Does each referral from an EN to a State VR agency require its own agreement?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Does each referral from an EN to a State VR agency require its own agreement? 411.410 Section 411.410 Employees' Benefits SOCIAL SECURITY...' Participation Agreements Between Employment Networks and State Vr Agencies § 411.410 Does each referral from...

  3. 20 CFR 411.410 - Does each referral from an EN to a State VR agency require its own agreement?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Does each referral from an EN to a State VR agency require its own agreement? 411.410 Section 411.410 Employees' Benefits SOCIAL SECURITY...' Participation Agreements Between Employment Networks and State Vr Agencies § 411.410 Does each referral from...

  4. 20 CFR 411.410 - Does each referral from an EN to a State VR agency require its own agreement?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Does each referral from an EN to a State VR agency require its own agreement? 411.410 Section 411.410 Employees' Benefits SOCIAL SECURITY...' Participation Agreements Between Employment Networks and State Vr Agencies § 411.410 Does each referral from...

  5. 77 FR 17095 - Solicitation for a Cooperative Agreement-Development of a Core Correctional Practices Curriculum

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-23

    ... National Institute of Corrections Solicitation for a Cooperative Agreement--Development of a Core...: Solicitation for a Cooperative Agreement. SUMMARY: The National Institute of Corrections (NIC) is soliciting proposals from organizations, groups, or individuals to enter into a cooperative agreement for a...

  6. 17 CFR 240.3a69-3 - Books and records requirements for security-based swap agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Books and records requirements... § 240.3a69-3 Books and records requirements for security-based swap agreements. (a) A person registered... and regulations thereunder: (1) Shall not be required to keep and maintain additional books...

  7. 17 CFR 240.3a69-3 - Books and records requirements for security-based swap agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Books and records requirements... § 240.3a69-3 Books and records requirements for security-based swap agreements. (a) A person registered... and regulations thereunder: (1) Shall not be required to keep and maintain additional books...

  8. 48 CFR 22.504 - General requirements for project labor agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... labor agreement; (2) Allow all contractors and subcontractors to compete for contracts and subcontracts without regard to whether they are otherwise parties to collective bargaining agreements; (3) Contain... concern, including productivity, quality of work, safety, and health; and (6) Include any...

  9. 25 CFR 84.003 - What types of contracts and agreements require Secretarial approval under this part?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Secretarial approval under this part? 84.003 Section 84.003 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF... contracts and agreements require Secretarial approval under this part? Unless otherwise provided in this... of seven or more years require Secretarial approval under this part....

  10. 25 CFR 84.003 - What types of contracts and agreements require Secretarial approval under this part?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Secretarial approval under this part? 84.003 Section 84.003 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF... contracts and agreements require Secretarial approval under this part? Unless otherwise provided in this... of seven or more years require Secretarial approval under this part....

  11. 25 CFR 84.003 - What types of contracts and agreements require Secretarial approval under this part?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Secretarial approval under this part? 84.003 Section 84.003 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF... contracts and agreements require Secretarial approval under this part? Unless otherwise provided in this... of seven or more years require Secretarial approval under this part....

  12. 25 CFR 84.003 - What types of contracts and agreements require Secretarial approval under this part?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Secretarial approval under this part? 84.003 Section 84.003 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF... contracts and agreements require Secretarial approval under this part? Unless otherwise provided in this... of seven or more years require Secretarial approval under this part....

  13. Development of an energy conservation voluntary agreement pilot project in the steel sector in Shandong

    SciTech Connect

    Price, Lynn; Yun, Jiang; Worrell, Ernst; Wenwei, Du; Sinton, Jonathan E.

    2004-02-05

    China faces a significant challenge in the years ahead to continue to provide essential materials and products for a rapidly-growing economy while addressing pressing environmental concerns. Energy is a fundamental element of the national economy and the conditions of its use have a direct impact on China's ability to reach its sustainable development goals. China's industrial sector, which accounts for over 70 percent of the nation's total energy consumption each year, provides materials such as steel and cement that build the nation's roads, bridges, homes, offices and other buildings. Industrial products include bicycles, cars, buses, trains, ships, office equipment, appliances, furniture, packaging, pharmaceuticals, and many other components of everyday life in an increasingly modern society. This vital production of materials and products, however, comes with considerable problems. China's industrial sector is heavily dependent on the country's abundant, yet polluting, coal resources. Industrial production locally pollutes the air with emissions of particulates, carbon monoxide, sulfur dioxide, and nitrogen oxides, uses scarce water and oil resources, emits greenhouse gases contributing to the warming global atmosphere, and often produces hazardous and polluting wastes. Fostering innovative approaches to reduce the use of polluting energy resources and to diminish pollution from industrial production that are tailored to China's emerging market-based economy is one of the most important challenges facing the nation today. The pressures of rapid industrial production growth, continued environmental degradation, and increased competition create a situation that calls for a strategically-planned evolution of China's industries into world-class production facilities that are competitive, energy-efficient and less polluting. Such a transition requires the complete commitment of industrial enterprises and the government to work together to transform the industrial

  14. 48 CFR 52.222-33 - Notice of Requirement for Project Labor Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... collective bargaining agreements; (3) Contain guarantees against strikes, lockouts, and similar job... cooperation on matters of mutual interest and concern, including productivity, quality of work, safety, and... ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text...

  15. 48 CFR 801.602-74 - Review requirements for an interagency agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Federal agency to be awarded under authority of the Economy Act, regardless of dollar value. For VA... facility interagency agreement with another Federal agency awarded under authority of the Economy...

  16. 76 FR 25362 - Cooperative Research and Development Agreement: Butanol Fuel Blend Usage With Marine Outboard...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-04

    ... regarding our public dockets in the January 17, 2008, issue of the Federal Register (73 FR 3316... SECURITY Coast Guard Cooperative Research and Development Agreement: Butanol Fuel Blend Usage With Marine... Agreement (CRADA) to identify and investigate the use of butanol fuel blends within marine outboard...

  17. 48 CFR 552.236-83 - Requirement for a Project Labor Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    .... “Project Labor Agreement” (PLA) means an agreement between the contractor, subcontractors, and the union(s) representing workers. Under a PLA, the contractor and subcontractors on a project and the union(s) agree on... Contractor shall, after contract award, enter into a PLA for performance of . The PLA binds the...

  18. 48 CFR 552.236-83 - Requirement for a Project Labor Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    .... “Project Labor Agreement” (PLA) means an agreement between the contractor, subcontractors, and the union(s) representing workers. Under a PLA, the contractor and subcontractors on a project and the union(s) agree on... Contractor shall, after contract award, enter into a PLA for performance of . The PLA binds the...

  19. 48 CFR 552.236-83 - Requirement for a Project Labor Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    .... “Project Labor Agreement” (PLA) means an agreement between the contractor, subcontractors, and the union(s) representing workers. Under a PLA, the contractor and subcontractors on a project and the union(s) agree on... Contractor shall, after contract award, enter into a PLA for performance of . The PLA binds the...

  20. 48 CFR 552.236-83 - Requirement for a Project Labor Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .... “Project Labor Agreement” (PLA) means an agreement between the contractor, subcontractors, and the union(s) representing workers. Under a PLA, the contractor and subcontractors on a project and the union(s) agree on... Contractor shall, after contract award, enter into a PLA for performance of . The PLA binds the...

  1. 48 CFR 552.236-83 - Requirement for a Project Labor Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    .... “Project Labor Agreement” (PLA) means an agreement between the contractor, subcontractors, and the union(s) representing workers. Under a PLA, the contractor and subcontractors on a project and the union(s) agree on... Contractor shall, after contract award, enter into a PLA for performance of . The PLA binds the...

  2. 40 CFR Appendix C-1 to Subpart E... - Required Provisions-Consulting Engineering Agreements

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... This agreement which covers grant-eligible work is subject to regulations contained in 40 CFR 35.936...'s control. Where innovative processes or techniques (see 40 CFR 35.908) are recommended by the... complete the task or Step in accordance with applicable EPA regulations (40 CFR part 35, subpart E...

  3. 40 CFR Appendix C-1 to Subpart E... - Required Provisions-Consulting Engineering Agreements

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    .... This agreement which covers grant-eligible work is subject to regulations contained in 40 CFR 35.936...'s control. Where innovative processes or techniques (see 40 CFR 35.908) are recommended by the... complete the task or Step in accordance with applicable EPA regulations (40 CFR part 35, subpart E...

  4. 40 CFR Appendix C-1 to Subpart E... - Required Provisions-Consulting Engineering Agreements

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    .... This agreement which covers grant-eligible work is subject to regulations contained in 40 CFR 35.936...'s control. Where innovative processes or techniques (see 40 CFR 35.908) are recommended by the... complete the task or Step in accordance with applicable EPA regulations (40 CFR part 35, subpart E...

  5. 78 FR 6772 - Failure To File Gain Recognition Agreements and Other Required Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-31

    ... FR 17936), addressing GRAs and reporting under section 6038B (1986 temporary regulations). The 1986... Amendments to the Section 367(a) GRA Regulations Under current law, if a U.S. transferor fails to timely file... Internal Revenue Service 26 CFR Part 1 RIN 1545-BK65 Failure To File Gain Recognition Agreements and...

  6. 78 FR 50424 - NIH Cooperative Research and Development Agreement Program: Invitation To Solicit Nonclinical and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-19

    ... HUMAN SERVICES National Institutes of Health NIH Cooperative Research and Development Agreement Program: Invitation To Solicit Nonclinical and Clinical Research Proposals From NIH Intramural Research Program... organizations); public and private foundations and nonprofit organizations to solicit research proposals...

  7. 78 FR 42084 - Cooperative Agreement to Support the World Trade Organization's Standards and Trade Development...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-15

    ... HUMAN SERVICES Food and Drug Administration Cooperative Agreement to Support the World Trade...) to the World Trade Organization's (WTO) Standards and Trade Development Facility (STDF). DATES... partnership established by the Food and Agriculture Organization, World Organization for Animal Health,...

  8. 33 CFR 155.4045 - Required agreements or contracts with the salvage and marine firefighting resource providers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... with the salvage and marine firefighting resource providers. 155.4045 Section 155.4045 Navigation and... MATERIAL POLLUTION PREVENTION REGULATIONS FOR VESSELS Salvage and Marine Firefighting § 155.4045 Required agreements or contracts with the salvage and marine firefighting resource providers. (a) You may only...

  9. 33 CFR 155.4045 - Required agreements or contracts with the salvage and marine firefighting resource providers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... with the salvage and marine firefighting resource providers. 155.4045 Section 155.4045 Navigation and... MATERIAL POLLUTION PREVENTION REGULATIONS FOR VESSELS Salvage and Marine Firefighting § 155.4045 Required agreements or contracts with the salvage and marine firefighting resource providers. (a) You may only...

  10. 45 CFR 205.58 - Income and eligibility information; specific agreements required between the State agency and the...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 2 2014-10-01 2012-10-01 true Income and eligibility information; specific agreements required between the State agency and the agency supplying the information. 205.58 Section 205.58 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND...

  11. 48 CFR 52.225-12 - Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Notice of Buy American Act... CONTRACT CLAUSES Text of Provisions and Clauses 52.225-12 Notice of Buy American Act Requirement...: Notice of Buy American Act Requirement—Construction Materials Under Trade Agreements (FEB 2009)...

  12. 48 CFR 52.225-12 - Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Notice of Buy American Act... CONTRACT CLAUSES Text of Provisions and Clauses 52.225-12 Notice of Buy American Act Requirement...: Notice of Buy American Act Requirement—Construction Materials Under Trade Agreements (FEB 2009)...

  13. 48 CFR 52.225-12 - Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Notice of Buy American Act... CONTRACT CLAUSES Text of Provisions and Clauses 52.225-12 Notice of Buy American Act Requirement...: Notice of Buy American Act Requirement—Construction Materials Under Trade Agreements (FEB 2009)...

  14. 48 CFR 52.225-12 - Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Notice of Buy American Act... CONTRACT CLAUSES Text of Provisions and Clauses 52.225-12 Notice of Buy American Act Requirement...: Notice of Buy American Act Requirement—Construction Materials Under Trade Agreements (FEB 2009)...

  15. 46 CFR 281.1 - Information and procedure required under liner operating-differential subsidy agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... options (such as facsimile and Internet) for transmission of required information to MARAD, if practicable... 46 Shipping 8 2010-10-01 2010-10-01 false Information and procedure required under liner operating... TRANSPORTATION REGULATIONS AFFECTING SUBSIDIZED VESSELS AND OPERATORS INFORMATION AND PROCEDURE REQUIRED...

  16. 14 CFR 213.7 - Filing requirements for adherence to Montreal Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... scheduled air transportation that the holder have and maintain in effect and on file with the Department a... generally required to file tariffs) that includes its provisions, and comply with all other requirements of part 203 of this chapter. That form can be obtained from the Foreign Air Carrier Licensing Division...

  17. 17 CFR 1.7 - Books and records requirements for security-based swap agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Books and records requirements... FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Definitions § 1.7 Books... not be required to keep and maintain additional books and records regarding security-based...

  18. 17 CFR 1.7 - Books and records requirements for security-based swap agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 1 2014-04-01 2014-04-01 false Books and records requirements... FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Definitions § 1.7 Books... not be required to keep and maintain additional books and records regarding security-based...

  19. Assessment of MSFCs Process for the Development and Activation of Space Act Agreement

    NASA Technical Reports Server (NTRS)

    Daugherty, Rachel

    2014-01-01

    Space Act Agreements (SAAs) are contractual agreements that NASA utilizes to form partnerships with researchers, industry, and academia to stimulate cutting-edge innovation within the science and technology communities. center dot This study assessed the current SAA development and activation process at Marshall Space Flight Center (MSFC) to determine if improvements could be implemented to increase productivity, decrease time to activation, and improve the quality of deliverables.

  20. 48 CFR 970.5235-1 - Federally funded research and development center sponsoring agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Sponsoring Agreement (DEC 2010) (a) Pursuant to 48 CFR 35.017-1, this contract constitutes the sponsoring... provided by the contract, the Contractor may accept work from a nonsponsor (as defined in 48 CFR 35.017) in accordance with the requirements and limitations of the clause 48 CFR 970.5217-1 Work for Others Program....

  1. 48 CFR 970.5235-1 - Federally funded research and development center sponsoring agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Sponsoring Agreement (DEC 2010) (a) Pursuant to 48 CFR 35.017-1, this contract constitutes the sponsoring... provided by the contract, the Contractor may accept work from a nonsponsor (as defined in 48 CFR 35.017) in accordance with the requirements and limitations of the clause 48 CFR 970.5217-1 Work for Others Program....

  2. 48 CFR 970.5235-1 - Federally funded research and development center sponsoring agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Sponsoring Agreement (DEC 2010) (a) Pursuant to 48 CFR 35.017-1, this contract constitutes the sponsoring... provided by the contract, the Contractor may accept work from a nonsponsor (as defined in 48 CFR 35.017) in accordance with the requirements and limitations of the clause 48 CFR 970.5217-1 Work for Others Program....

  3. 48 CFR 970.5235-1 - Federally funded research and development center sponsoring agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Sponsoring Agreement (DEC 2010) (a) Pursuant to 48 CFR 35.017-1, this contract constitutes the sponsoring... provided by the contract, the Contractor may accept work from a nonsponsor (as defined in 48 CFR 35.017) in accordance with the requirements and limitations of the clause 48 CFR 970.5217-1 Work for Others Program....

  4. Development and implementation of the Good Neighbor Agreement (GNA) practice in the USA sustainable mining development.

    NASA Astrophysics Data System (ADS)

    Masaitis, Alexandra

    2014-05-01

    New economic, environmental and social challenges for the mining industry in the USA show the need to implement "responsible" mining practices that include improved community involvement. Conflicts which occur in the US territory and with US mining companies around the world are now common between the mining proponents, NGO's and communities. These conflicts can sometimes be alleviated by early development of modes of communication, and a formal discussion format that allows airing of concerns and potential resolution of problems. One of the methods that can formalize this process is to establish a Good Neighbor Agreement (GNA), which deals specifically with challenges in relationships between mining operations and the local communities. It is a new practice related to mining operations that are oriented toward social needs and concerns of local communities that arise during the normal life of a mine, which can achieve sustainable mining practices. The GNA project being currently developed at the University of Nevada, USA in cooperation with the Newmont Mining Corporation has a goal of creating an open company/community dialog that will help identify and address sociological and environmental concerns associated with mining. Discussion: The Good Neighbor Agreement currently evolving will address the following: 1. Identify spheres of possible cooperation between mining companies, government organizations, and NGO's. 2. Provide an economically viable mechanism for developing a partnership between mining operations and the local communities that will increase mining industry's accountability and provide higher levels of confidence for the community that a mine is operated in a safe and sustainable manner. Implementation of the GNA can help identify and evaluate conflict criteria in mining/community relationships; determine the status of concerns; determine the role and responsibilities of stakeholders; analyze problem resolution feasibility; maintain the community

  5. Development of a multi-party cooperative agreement at a Formerly Used Defense Site

    SciTech Connect

    Bilington, T.L.; Snowdon, J.P.; Mitchell, J.

    1994-12-31

    This paper presents a case study of the development of a multiple party cooperative agreement for a Formerly Used Defense Site (FUDS). The FUDS is located in the California Central Valley and was used as an Army Air Corps facility during World War II. Ground water contamination has been found in nearby public drinking water supply wells and the extent of contamination is currently being investigated. This paper will discuss various perspectives on the Cooperative Agreement. Those perspectives will include that of the California Department of Toxic Substances Control (Department), the lead state regulatory agency; the US Army Corps of Engineers Omaha District (USACE-Omaha), responsible for the Department of Defense (DOD) FUDS program for this site; and the City of Fresno, the current landowner. Further, this paper will discuss the site history, the regulatory history, the current status of the agreement, the current status of the site investigation, and plans for future activities at the site. The key issues of the Cooperative Agreement will also be discussed. Those key issues include: (1) the main points of contention between the various parties to the Cooperative Agreement; (2) problems encountered during the development of the Cooperative Agreement; and (3) how those points or problems were resolved. Finally, this paper summarizes the lessons learned with a brief retrospective of the parties` involvement in the process.

  6. Learning Agreements and Socially Responsible Approaches to Professional and Human Resource Development in the United Kingdom

    ERIC Educational Resources Information Center

    Wallis, Emma

    2008-01-01

    This article draws upon original qualitative data to present an initial assessment of the significance of learning agreements for the development of socially responsible approaches to professional and human resource development within the workplace. The article suggests that the adoption of a partnership-based approach to learning is more…

  7. 77 FR 19678 - Cooperative Research and Development Agreement: Asset Tracking and Reporting Technology

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-02

    ... Register (73 FR 3316). Cooperative Research and Development Agreements Cooperative Research and Development... (CRADA) with General Dynamics C4 Systems, Inc. (General Dynamics), to test, evaluate, and document the... participants would test, evaluate, and document the strengths and weaknesses of at least one technical...

  8. 77 FR 1708 - Cooperative Research and Development Agreement: Technology To Provide Wireless Precise Time...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-11

    ... Register (73 FR 3316). Cooperative Research and Development Agreements Cooperative Research and Development... conducting live, on-air tests that will be broadcast from former Long Range Navigation (LORAN) sites, using... these test broadcasts are planned at both on-shore and off-shore locations. The testing will...

  9. 10 CFR 150.17a - Compliance with requirements of US/IAEA Safeguards Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... information on DOC/NRC Form AP-A and associated forms; (2) As required by the Additional Protocol, shall submit location information described in § 75.11 of this chapter on DOC/NRC Form AP-1 and associated... associated forms, and site information on DOC/NRC Form AP-A and associated forms; shall submit...

  10. 10 CFR 150.17a - Compliance with requirements of US/IAEA Safeguards Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... information on DOC/NRC Form AP-A and associated forms; (2) As required by the Additional Protocol, shall submit location information described in § 75.11 of this chapter on DOC/NRC Form AP-1 and associated... associated forms, and site information on DOC/NRC Form AP-A and associated forms; shall submit...

  11. 10 CFR 150.17a - Compliance with requirements of US/IAEA Safeguards Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... information on DOC/NRC Form AP-A and associated forms; (2) As required by the Additional Protocol, shall submit location information described in § 75.11 of this chapter on DOC/NRC Form AP-1 and associated... associated forms, and site information on DOC/NRC Form AP-A and associated forms; shall submit...

  12. 10 CFR 150.17a - Compliance with requirements of US/IAEA Safeguards Agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... information on DOC/NRC Form AP-A and associated forms; (2) As required by the Additional Protocol, shall submit location information described in § 75.11 of this chapter on DOC/NRC Form AP-1 and associated... associated forms, and site information on DOC/NRC Form AP-A and associated forms; shall submit...

  13. 43 CFR 414.4 - Reporting requirements and accounting under Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Relating to Public Lands BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF INTENTIONALLY CREATED UNUSED APPORTIONMENT IN THE...

  14. 43 CFR 414.4 - Reporting requirements and accounting under Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Relating to Public Lands BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF INTENTIONALLY CREATED UNUSED APPORTIONMENT IN THE...

  15. 43 CFR 414.4 - Reporting requirements and accounting under Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... to Public Lands BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF INTENTIONALLY CREATED UNUSED APPORTIONMENT IN THE LOWER...

  16. 43 CFR 414.4 - Reporting requirements and accounting under Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Relating to Public Lands BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF INTENTIONALLY CREATED UNUSED APPORTIONMENT IN THE...

  17. 43 CFR 414.4 - Reporting requirements and accounting under Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Relating to Public Lands BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF INTENTIONALLY CREATED UNUSED APPORTIONMENT IN THE...

  18. 25 CFR 84.007 - What is the status of a contract or agreement that requires Secretarial approval under this part...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... requires Secretarial approval under this part but has not yet been approved? 84.007 Section 84.007 Indians...-CONTRACT APPROVALS § 84.007 What is the status of a contract or agreement that requires Secretarial approval under this part but has not yet been approved? A contract or agreement that requires...

  19. 25 CFR 84.007 - What is the status of a contract or agreement that requires Secretarial approval under this part...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... requires Secretarial approval under this part but has not yet been approved? 84.007 Section 84.007 Indians...-CONTRACT APPROVALS § 84.007 What is the status of a contract or agreement that requires Secretarial approval under this part but has not yet been approved? A contract or agreement that requires...

  20. 25 CFR 84.007 - What is the status of a contract or agreement that requires Secretarial approval under this part...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... requires Secretarial approval under this part but has not yet been approved? 84.007 Section 84.007 Indians...-CONTRACT APPROVALS § 84.007 What is the status of a contract or agreement that requires Secretarial approval under this part but has not yet been approved? A contract or agreement that requires...

  1. 25 CFR 84.007 - What is the status of a contract or agreement that requires Secretarial approval under this part...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... requires Secretarial approval under this part but has not yet been approved? 84.007 Section 84.007 Indians...-CONTRACT APPROVALS § 84.007 What is the status of a contract or agreement that requires Secretarial approval under this part but has not yet been approved? A contract or agreement that requires...

  2. 25 CFR 84.007 - What is the status of a contract or agreement that requires Secretarial approval under this part...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... requires Secretarial approval under this part but has not yet been approved? 84.007 Section 84.007 Indians...-CONTRACT APPROVALS § 84.007 What is the status of a contract or agreement that requires Secretarial approval under this part but has not yet been approved? A contract or agreement that requires...

  3. Space Act Agreement Maker (SAAM) With Electronic Routing System (ERouter) Developed

    NASA Technical Reports Server (NTRS)

    Stauber, Laurel J.

    2003-01-01

    Members of the Commercial Technology Office at the NASA Glenn Research Center have developed an exciting new tool that greatly reduces the lead time in creating and routing Space Act Agreements. The Space Act Agreement Maker (SAAM) is an e-government Web-based system that automates the initial drafting of Space Act Agreements by technical and program personnel. SAAM also is used for editing and will be used later for maintaining electronic copies of all Space Act Agreements. During the initial drafting, the software prompts NASA personnel proposing an agreement to answer questions regarding the agreement. On the basis of the answers, the software selects from a matrix of NASA standard clauses to produce a first draft of the agreement. The draft agreement and information submitted by the NASA personnel are electronically routed to Glenn s Commercial Technology Office for review and, where necessary, editing. The final version of the agreement, along with any supporting documentation, is then routed for electronic concurrence/approval to the necessary internal review participants using the electronic routing system (e-router). SAAM was developed cooperatively by Glenn s Commercial Technology Office and Glenn s Office of Chief Counsel. Currently, SAAM is being evaluated by the NASA Headquarters General Counsel Office for use at all NASA centers. This system allows for the effective processing of Space Act Agreements for NASA s internal and external customers. Document control is maintained by a database. With SAAM s electronic routing, review times can be reduced significantly, allowing Glenn to more rapidly establish partnerships with industry. Prior to the creation of SAAM, it took several hours to draft a Space Act Agreement. With SAAM in place, the document can be written in about 30 min. Using the e-router also saves time in determining where the agreement is in the routing process. The document can be tracked easily, and delays can be avoided. Important research

  4. 77 FR 39741 - Solicitation for a Cooperative Agreement-Curricula Review and Revision: NIC Trainer Development...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-05

    ...The National Institute of Corrections' (NIC) Academy Division is soliciting proposals from organizations, groups, or individuals to enter into a cooperative agreement for the review, revision, and/or development of competency-based, blended modality training curricula with the aim of providing corrections agencies and professionals with the knowledge, skills, and abilities needed to train and......

  5. 34 CFR 363.50 - What collaborative agreements must the State develop?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false What collaborative agreements must the State develop? 363.50 Section 363.50 Education Regulations of the Offices of the Department of Education (Continued... EMPLOYMENT SERVICES PROGRAM What Post-Award Conditions Must Be Met by a State? § 363.50 What...

  6. 34 CFR 363.50 - What collaborative agreements must the State develop?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true What collaborative agreements must the State develop? 363.50 Section 363.50 Education Regulations of the Offices of the Department of Education (Continued... EMPLOYMENT SERVICES PROGRAM What Post-Award Conditions Must Be Met by a State? § 363.50 What...

  7. 34 CFR 363.50 - What collaborative agreements must the State develop?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true What collaborative agreements must the State develop? 363.50 Section 363.50 Education Regulations of the Offices of the Department of Education (Continued... EMPLOYMENT SERVICES PROGRAM What Post-Award Conditions Must Be Met by a State? § 363.50 What...

  8. 34 CFR 363.50 - What collaborative agreements must the State develop?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false What collaborative agreements must the State develop? 363.50 Section 363.50 Education Regulations of the Offices of the Department of Education (Continued... EMPLOYMENT SERVICES PROGRAM What Post-Award Conditions Must Be Met by a State? § 363.50 What...

  9. 34 CFR 363.50 - What collaborative agreements must the State develop?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false What collaborative agreements must the State develop? 363.50 Section 363.50 Education Regulations of the Offices of the Department of Education (Continued... EMPLOYMENT SERVICES PROGRAM What Post-Award Conditions Must Be Met by a State? § 363.50 What...

  10. 77 FR 31008 - Enforceable Consent Agreement Development for Two Cyclic Siloxanes; Solicitation of Interested...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-24

    .... Final Rule. 54 FR 818, January 10, 1989. 3. SEHSC. Memorandum from Karluss Thomas. Executive Director... the Dow Corning Corporation; Notice of Receipt and Availability of the MOU Data. 74 FR 38013, July 30... AGENCY Enforceable Consent Agreement Development for Two Cyclic Siloxanes; Solicitation of...

  11. 75 FR 56112 - Integrated Food Safety System Online Collaboration Development-Cooperative Agreement With the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... HUMAN SERVICES Food and Drug Administration Integrated Food Safety System Online Collaboration Development-- Cooperative Agreement With the National Center for Food Protection and Defense (U18) AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA)...

  12. The Development of a Revised Written Agreement Between Affiliated Clinical Sites and Spartanburg Technical College.

    ERIC Educational Resources Information Center

    Atkins, Karen B.

    In 1968, an affiliation agreement was developed between Spartanburg Technical College (STC) and the first clinical site that provided the medical and health laboratory facilities necessary for the on-site training of STC's allied health science students. By 1978, a number of administrative and policy changes that had taken place at Spartanburg and…

  13. 48 CFR 970.5235-1 - Federally funded research and development center sponsoring agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Sponsoring Agreement (DEC 2000) (a) Pursuant to 48 CFR 35.017-1, this contract constitutes the sponsoring... the operation of a Department of Energy sponsored Federally Funded Research and Development Center... provided by the contract, the Contractor may accept work from a nonsponsor (as defined in 48 CFR 35.017)...

  14. 77 FR 25488 - Cooperative Research and Development Agreement: Federally Integrated Communications System

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-30

    ...The Coast Guard is announcing its intent to enter into a Cooperative Research and Development Agreement (CRADA) with General Dynamics C4 Systems, Inc. to lab demonstrate, field test, evaluate, and document at least one technical approach to show interoperability, with end-to-end encryption, for disparate Federal communications systems at the Internet Protocol level. The Coast Guard invites......

  15. 77 FR 48165 - Cooperative Research and Development Agreement (CRADA) Opportunity With the Department of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Cooperative Research and Development Agreement (CRADA) Opportunity With the Department of Homeland Security for the Efficacy Testing of Vaporous Hydrogen Peroxide (VHP) and Chlorine Dioxide (ClO 2 )...

  16. Assessing implementation mechanisms for an international agreement on research and development for health products.

    PubMed

    Hoffman, Steven J; Røttingen, John-Arne

    2012-11-01

    The Member States of the World Health Organization (WHO) are currently debating the substance and form of an international agreement to improve the financing and coordination of research and development (R&D) for health products that meet the needs of developing countries. In addition to considering the content of any possible legal or political agreement, Member States may find it helpful to reflect on the full range of implementation mechanisms available to bring any agreement into effect. These include mechanisms for states to make commitments, administer activities, manage financial contributions, make subsequent decisions, monitor each other's performance and promote compliance. States can make binding or non-binding commitments through conventions, contracts, declarations or institutional reforms. States can administer activities to implement their agreements through international organizations, sub-agencies, joint ventures or self-organizing processes. Finances can be managed through specialized multilateral funds, financial institutions, membership organizations or coordinated self-management. Decisions can be made through unanimity, consensus, equal voting, modified voting or delegation. Oversight can be provided by peer review, expert review, self-reports or civil society. Together, states should select their preferred options across categories of implementation mechanisms, each of which has advantages and disadvantages. The challenge lies in choosing the most effective combinations of mechanisms for supporting an international agreement (or set of agreements) that achieves collective aspirations in a way and at a cost that are both sustainable and acceptable to those involved. In making these decisions, WHO's Member States can benefit from years of experience with these different mechanisms in health and its related sectors. PMID:23226898

  17. Assessing implementation mechanisms for an international agreement on research and development for health products

    PubMed Central

    Røttingen, John-Arne

    2012-01-01

    Abstract The Member States of the World Health Organization (WHO) are currently debating the substance and form of an international agreement to improve the financing and coordination of research and development (R&D) for health products that meet the needs of developing countries. In addition to considering the content of any possible legal or political agreement, Member States may find it helpful to reflect on the full range of implementation mechanisms available to bring any agreement into effect. These include mechanisms for states to make commitments, administer activities, manage financial contributions, make subsequent decisions, monitor each other’s performance and promote compliance. States can make binding or non-binding commitments through conventions, contracts, declarations or institutional reforms. States can administer activities to implement their agreements through international organizations, sub-agencies, joint ventures or self-organizing processes. Finances can be managed through specialized multilateral funds, financial institutions, membership organizations or coordinated self-management. Decisions can be made through unanimity, consensus, equal voting, modified voting or delegation. Oversight can be provided by peer review, expert review, self-reports or civil society. Together, states should select their preferred options across categories of implementation mechanisms, each of which has advantages and disadvantages. The challenge lies in choosing the most effective combinations of mechanisms for supporting an international agreement (or set of agreements) that achieves collective aspirations in a way and at a cost that are both sustainable and acceptable to those involved. In making these decisions, WHO’s Member States can benefit from years of experience with these different mechanisms in health and its related sectors. PMID:23226898

  18. Uniform administrative requirements for grants and agreements with institutions of higher education, hospitals, other non-profit, and commercial organizations--Department of Commerce. Interim final rule.

    PubMed

    1998-09-01

    This interim final rule implements the revisions to the Office of Management and Budget (OMB) Circular A-110, "Uniform Administrative Requirements for Grants and Agreements With Institutions of Higher Education, Hospitals, and Other Non-Profit Organizations" which was published in the Federal Register on November 29, 1993. The revised Circular was developed by an interagency task force for governmentwide use in a model rule format to facilitate regulatory adoption by executive departments and agencies. In the published revised Circular, OMB specified as "required action" that Federal agencies responsible for awarding and administering grants and other agreements to recipients described therein, shall adopt the language of the Circular unless other provisions are required by Federal statute or exceptions or deviations are approved by OMB. This interim final rule adopts the provisions of the Circular and its language to the maximum extent feasible. However, minor changes were made to update the procedures, clarify the language, and make the language apply specifically to the DoC and its operating units. No changes are intended to deviate from the substance of Circular A-110. The Circular covers both grants and cooperative agreements made by Federal agencies and subawards, unless sections of the Circular specifically exclude subrecipients from coverage. Consistent with guidance provided in the Circular, DoC will apply its provisions to grants and agreements with institutions of higher education, hospitals, other nonprofit, and commercial organizations. The provisions of the interim final rule will also apply to foreign governments, organizations under the jurisdiction of foreign governments, and international organizations when appropriate. PMID:10182710

  19. 77 FR 4363 - Solicitation for a Cooperative Agreement-Curriculum Development: Thinking for a Change 3.1...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-27

    ... National Institute of Corrections Solicitation for a Cooperative Agreement--Curriculum Development.... Department of Justice. ACTION: Solicitation for a Cooperative Agreement. SUMMARY: The National Institute of... curriculum for T4C 3.1 Training for Facilitators. Scope of Work: At the end of this cooperative agreement,...

  20. A national laboratory/private industry cooperative research and development agreement (CRADA)

    SciTech Connect

    Pritchard, D.A.; MacEachin, J.

    1996-09-01

    This paper provides an overview of the history and process of establishing a cooperative research and development agreement (CRADA) between Sandia National Laboratories and Magnavox Electronic Systems Company for the design, development, and testing of a 360-degree scanning, imaging, intrusion detection sensor. The subject of the CRADA is the Advanced Exterior Sensor (AES). It is intended for exterior use at ranges from 50 to 1,500 meters and uses a combination of three sensing technologies (infrared, visible, and radar) and a new data processing method to provide low false-alarm intrusion detection and tracking combined with immediate visual assessment. The establishment of this CRADA represents a new paradigm in the cooperation between the Department of Defense, the Department of Energy, the National Laboratories and Private Industry. Although a formal document has now been executed, a CRADA is, nonetheless, primarily an agreement to work with each other to achieve goals that might otherwise be unattainable.

  1. Space power development impact on technology requirements

    NASA Technical Reports Server (NTRS)

    Cassidy, J. F.; Fitzgerald, T. J.; Gilje, R. I.; Gordon, J. D.

    1986-01-01

    The paper is concerned with the selection of a specific spacecraft power technology and the identification of technology development to meet system requirements. Requirements which influence the selection of a given technology include the power level required, whether the load is constant or transient in nature, and in the case of transient loads, the time required to recover the power, and overall system safety. Various power technologies, such as solar voltaic power, solar dynamic power, nuclear power systems, and electrochemical energy storage, are briefly described.

  2. Advanced Extravehicular Activity Pressure Garment Requirements Development

    NASA Technical Reports Server (NTRS)

    Ross, Amy

    2014-01-01

    The NASA Johnson Space Center advanced pressure garment technology development team is addressing requirements development for exploration missions. Lessons learned from the Z-2 high fidelity prototype development have reiterated that clear low-level requirements and verification methods reduce risk to the government, improve efficiency in pressure garment design efforts, and enable the government to be a smart buyer. The expectation is to provide requirements at the specification level that are validated so that their impact on pressure garment design is understood. Additionally, the team will provide defined verification protocols for the requirements. However, in reviewing exploration space suit high level requirements there are several gaps in the team's ability to define and verify related lower level requirements. This paper addresses the efforts in requirement areas such as mobility/fit/comfort and environmental protection (dust, radiation, plasma, secondary impacts) to determine the by what method the requirements can be defined and use of those methods for verification. Gaps exist at various stages. In some cases component level work is underway, but no system level effort has begun, in other cases no effort has been initiated to close the gap. Status of ongoing efforts and potential approaches to open gaps are discussed.

  3. A Best Practice for Developing Availability Guarantee Language in Photovoltaic (PV) O&M Agreements.

    SciTech Connect

    Klise, Geoffrey Taylor; Balfour, John

    2015-11-01

    This document outlines the foundation for developing language that can be utilized in an Equipment Availability Guarantee, typically included in an O&M services agreement between a PV system or plant owner and an O&M services provider, or operator. Many of the current PV O&M service agreement Availability Guarantees are based on contracts used for traditional power generation, which create challenges for owners and operators due to the variable nature of grid-tied photovoltaic generating technologies. This report documents language used in early PV availability guarantees and presents best practices and equations that can be used to more openly communicate how the reliability of the PV system and plant equipment can be expressed in an availability guarantee. This work will improve the bankability of PV systems by providing greater transparency into the equipment reliability state to all parties involved in an O&M services contract.

  4. Requirements development for a patient computing system.

    PubMed Central

    Wald, J. S.; Pedraza, L. A.; Reilly, C. A.; Murphy, M. E.; Kuperman, G. J.

    2001-01-01

    Critical parts of the software development life cycle are concerned with eliciting, understanding, and managing requirements. Though the literature on this subject dates back for several decades, practicing effective requirements development remains a current and challenging area. Some projects flourish with a requirements development process (RDP) that is implicit and informal, but this approach may be overly risky, particularly for large projects that involve multiple individuals, groups, and systems over time. At Partners HealthCare System in Boston, Massachusetts, we have applied a more formal approach for requirements development to the Patient Computing Project. The goal of the project is to create web-based software that connects patients electronically with their physician's offices and has the potential to improve care efficiency and quality. It is a large project, with over 500 function points. Like most technological innovation, the successful introduction of this system requires as much attention to understanding the business needs and workflow details as it does to technical design and implementation. This paper describes our RDP approach, and key business requirements discovered through this process. We believe that a formal RDP is essential, and that informatics as a field must include proficiencies in this area. PMID:11825282

  5. Projected uranium requirements of developing countries

    SciTech Connect

    1990-02-01

    The objective of this paper is to examine the uranium requirements of developing countries both in aggregate and individually. Although the cumulative uranium requirements of these countries are expected to account for less than eight percent of total requirements, the fact that many of these countries are expressing renewed interest in nuclear is, in itself, encouraging. The countries analyzed in this paper are Argentina, Brazil, Egypt, India, Israel, Mexico, Pakistan, South Africa, South Korea and Taiwan. For each country, the existing and planned nuclear capacity levels have been identified and capacity factors have been projected. For countries with no previous nuclear power, the world weighted average capacity factor for the specific reactor type is utilized. Other factors influencing nuclear power demand and operations of these developing countries will be discussed, and finally, uranium requirements based on a calculated optimal tails assay of .30 will be provided.

  6. Nondestructive testing of ceramic components: Cooperative research and development agreement completion report

    SciTech Connect

    Carpenter, D.A.; Dews, T.W.; Moyer, M.W.; Oakes, R.E.

    1994-12-22

    In a joint Cooperative Research and Development Agreement (CRADA) between Martin Marietta Energy Systems (MMES) and an industrial partner, Y-12 has been evaluating nondestructive evaluation (NDE) techniques to identify the quality of high strength aluminum oxide tubes used in laser applications. In Phase I, several NDE techniques were developed to inspect the tubes. In Phase II a correlation between detected defects, actual failure mode and strength of the tubes was developed. In Phase II the industrial partner supplied tubes manufactured under a variety of conditions and containing material defects expected from process control variations. The tubes were inspected at MMES utilizing a variety of available acoustic techniques. After inspection, ring tensile specimens were fabricated to determine the tensile strength. The data were evaluated utilizing Weibull statistics to determine the statistical impact of the defects upon strength and correlate the data with the nondestructive evaluations of the tubes and observed defect distribution.

  7. Technology Cooperation Agreement Pilot Project development-friendly greenhouse gas reduction, May 1999 update

    SciTech Connect

    Benioff, R.

    1999-05-11

    The Technology Cooperation Agreement Pilot Project (TCAPP) was launched by several U.S. Government agencies (USAID, EPA and DOE) in August 1997 to establish a model for climate change technology cooperation with developing and transition countries. TCAPP is currently facilitating voluntary partnerships between the governments of Brazil, China, Kazakhstan, Korea, Mexico, and the Philippines, the private sector, and the donor community on a common set of actions that will advance implementation of clean energy technologies. The six participating countries have been actively engaged in shaping this initiative along with international donors and the private sector. This program helps fulfill the US obligation to support technology transfer to developing countries under Article 4.5 of the United Nations Framework Convention on Climate Change. TCAPP also provides a mechanism to focus resources across international donor programs on the technology cooperation needs of developing and transition countries.

  8. Developing communications requirements for Agile Product Realization

    SciTech Connect

    Forsythe, C.; Ashby, M.R.

    1994-03-01

    Sandia National Laboratories has undertaken the Agile Product Realization for Innovative electroMEchanical Devices (A-PRIMED) pilot project to develop and implement technologies for agile design and manufacturing of electrochemical components. Emphasis on information-driven processes, concurrent engineering and multi-functional team communications makes computer-supported cooperative work critical to achieving significantly faster product development cycles. This report describes analyses conducted in developing communications requirements and a communications plan that addresses the unique communications demands of an agile enterprise.

  9. Framework Requirements for MDO Application Development

    NASA Technical Reports Server (NTRS)

    Salas, A. O.; Townsend, J. C.

    1999-01-01

    Frameworks or problem solving environments that support application development form an active area of research. The Multidisciplinary Optimization Branch at NASA Langley Research Center is investigating frameworks for supporting multidisciplinary analysis and optimization research. The Branch has generated a list of framework requirements, based on the experience gained from the Framework for Interdisciplinary Design Optimization project and the information acquired during a framework evaluation process. In this study, four existing frameworks are examined against these requirements. The results of this examination suggest several topics for further framework research.

  10. 78 FR 43923 - Solicitation for a Cooperative Agreement-Executive Excellence a Training and Development Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-22

    ... National Institute of Corrections Solicitation for a Cooperative Agreement--Executive Excellence a Training.... Department of Justice. ACTION: Solicitation for a Cooperative Agreement. SUMMARY: The National Institute of... cooperative agreement for a 15-month period to begin no later than September 15, 2013. This project will be...

  11. 78 FR 43925 - Solicitation for a Cooperative Agreement-Executive Excellence a Training and Development Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-22

    ... National Institute of Corrections Solicitation for a Cooperative Agreement--Executive Excellence a Training.... Department of Justice. ACTION: Solicitation for a Cooperative Agreement. SUMMARY: The National Institute of... cooperative agreement for a 15-month period to begin no later than September 15, 2013. This project will be...

  12. Development of a cost-effectiveness analysis of leafy green marketing agreement irrigation water provisions.

    PubMed

    Jensen, Helen H; Pouliot, Sébastien; Wang, Tong; Jay-Russell, Michele T

    2014-06-01

    An analysis of the effectiveness of meeting the irrigation water provisions of the Leafy Green Marketing Agreement (LGMA) relative to its costs provides an approach to evaluating the cost-effectiveness of good agricultural practices that uses available data. A case example for lettuce is used to evaluate data requirements and provide a methodological example to determine the cost-effectiveness of the LGMA water quality provision. Both cost and field data on pathogen or indicator bacterial levels are difficult and expensive to obtain prospectively. Therefore, methods to use existing field and experimental data are required. Based on data from current literature and experimental studies, we calculate a cost-efficiency ratio that expresses the reduction in E. coli concentration per dollar expenditure on testing of irrigation water. With appropriate data, the same type of analysis can be extended to soil amendments and other practices and to evaluation of public benefits of practices used in production. Careful use of existing and experimental data can lead to evaluation of an expanded set of practices. PMID:24853531

  13. 25 CFR 84.004 - Are there types of contracts and agreements that do not require Secretarial approval under this...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... law or regulation. See, for example, 25 CFR parts 152 (patents in fee, certificates or competency... tribal laws or custom; (e) Contracts or agreements that do not convey exclusive or nearly exclusive...-Governance Act, 25 U.S.C. 458aa. (i) Contracts or agreements that are subject to approval by the...

  14. 25 CFR 84.004 - Are there types of contracts and agreements that do not require Secretarial approval under this...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... law or regulation. See, for example, 25 CFR parts 152 (patents in fee, certificates or competency... tribal laws or custom; (e) Contracts or agreements that do not convey exclusive or nearly exclusive...-Governance Act, 25 U.S.C. 458aa. (i) Contracts or agreements that are subject to approval by the...

  15. 25 CFR 84.004 - Are there types of contracts and agreements that do not require Secretarial approval under this...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... law or regulation. See, for example, 25 CFR parts 152 (patents in fee, certificates or competency... tribal laws or custom; (e) Contracts or agreements that do not convey exclusive or nearly exclusive...-Governance Act, 25 U.S.C. 458aa. (i) Contracts or agreements that are subject to approval by the...

  16. 75 FR 61503 - Cooperative Agreement With the World Health Organization for a Plan to Develop a Global...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-05

    ... HUMAN SERVICES Food and Drug Administration Cooperative Agreement With the World Health Organization for a Plan to Develop a Global Integrated Food Safety Information Platform AGENCY: Food and Drug... accept and consider a single source application for awarding a cooperative agreement to the World...

  17. 28 CFR 56.2 - Maintenance of records with respect to meetings held to develop voluntary agreements or plans of...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Maintenance of records with respect to meetings held to develop voluntary agreements or plans of action pursuant to the Agreement on an International Energy Program. 56.2 Section 56.2 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) INTERNATIONAL ENERGY PROGRAM § 56.2...

  18. 28 CFR 56.2 - Maintenance of records with respect to meetings held to develop voluntary agreements or plans of...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Maintenance of records with respect to meetings held to develop voluntary agreements or plans of action pursuant to the Agreement on an International Energy Program. 56.2 Section 56.2 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) INTERNATIONAL ENERGY PROGRAM § 56.2...

  19. Assessment of MSFCs Process for the Development and Activation of Space Act Agreements

    NASA Technical Reports Server (NTRS)

    Daugherty, Rachel A.

    2014-01-01

    A Space Act Agreement (SAA) is a contractual vehicle that NASA utilizes to form partnerships with non-NASA entities to stimulate cutting-edge innovation within the science and technology communities while concurrently supporting the NASA missions. SAAs are similar to traditional contracts in that they involve the commitment of Agency resources but allow more flexibility and are more cost effective to implement than traditional contracts. Consequently, the use of SAAs to develop partnerships has greatly increased over the past several years. To facilitate this influx of SAAs, Marshall Space Flight Center (MSFC) developed a process during a kaizen event to streamline and improve the quality of SAAs developed at the Center level. This study assessed the current SAA process to determine if improvements could be implemented to increase productivity, decrease time to activation, and improve the quality of deliverables. Using a combination of direct procedural observation, personnel interviews, and statistical analysis, elements of the process in need of remediation were identified and potential solutions developed. The findings focus primarily on the difficulties surrounding tracking and enforcing process adherence and communication issues among stakeholders. Potential solutions include utilizing customer relationship management (CRM) software to facilitate process coordination and co-locating or potentially merging the two separate organizations involved in SAA development and activation at MSFC.

  20. Development of a National Agreement on Human Papillomavirus Vaccination in Japan: An Infodemiology Study

    PubMed Central

    Yuji, Koichiro; Tsubokura, Masaharu; Ohsawa, Yukio; Kami, Masahiro

    2014-01-01

    Background A national agreement on human papillomavirus (HPV) vaccination was achieved relatively quickly in Japan as compared to the United States and India. Objective The objective was to identify the role of print and online media references, including references to celebrities or other informants, as factors potentially responsible for the relatively rapid national acceptance of HPV vaccination in Japan. Methods A method of text mining was performed to select keywords, representing the context of the target documents, from articles relevant to the promotion of HPV vaccination appearing in major Japanese newspapers and Web pages between January 2009 and July 2010. The selected keywords were classified as positive, negative, or neutral, and the transition of the frequency of their appearance was analyzed. Results The number of positive and neutral keywords appearing in newspaper articles increased sharply in early 2010 while the number of negative keywords remained low. The numbers of positive, neutral, and negative keywords appearing in Web pages increased gradually and did not significantly differ by category. Neutral keywords, such as “vaccine” and “prevention,” appeared more frequently in newspaper articles, whereas negative keywords, such as “infertility” and “side effect,” appeared more frequently in Web pages. The extraction of the positive keyword “signature campaign” suggests that vaccine beneficiaries cooperated with providers in promoting HPV vaccination. Conclusions The rapid development of a national agreement regarding HPV vaccination in Japan may be primarily attributed to the advocacy of vaccine beneficiaries, supported by advocacy by celebrities and positive reporting by print and online media. PMID:24834471

  1. Distinct requirements for Wntless in habenular development.

    PubMed

    Kuan, Yung-Shu; Roberson, Sara; Akitake, Courtney M; Fortuno, Lea; Gamse, Joshua; Moens, Cecilia; Halpern, Marnie E

    2015-10-15

    Secreted Wnt proteins play pivotal roles in development, including regulation of cell proliferation, differentiation, progenitor maintenance and tissue patterning. The transmembrane protein Wntless (Wls) is necessary for secretion of most Wnts and essential for effective Wnt signaling. During a mutagenesis screen to identify genes important for development of the habenular nuclei in the dorsal forebrain, we isolated a mutation in the sole wls gene of zebrafish and confirmed its identity with a second, independent allele. Early embryonic development appears normal in homozygous wls mutants, but they later lack the ventral habenular nuclei, form smaller dorsal habenulae and otic vesicles, have truncated jaw and fin cartilages and lack swim bladders. Activation of a reporter for β-catenin-dependent transcription is decreased in wls mutants, indicative of impaired signaling by the canonical Wnt pathway, and expression of Wnt-responsive genes is reduced in the dorsal diencephalon. Wnt signaling was previously implicated in patterning of the zebrafish brain and in the generation of left-right (L-R) differences between the bilaterally paired dorsal habenular nuclei. Outside of the epithalamic region, development of the brain is largely normal in wls mutants and, despite their reduced size, the dorsal habenulae retain L-R asymmetry. We find that homozygous wls mutants show a reduction in two cell populations that contribute to the presumptive dorsal habenulae. The results support distinct temporal requirements for Wls in habenular development and reveal a new role for Wnt signaling in the regulation of dorsal habenular progenitors. PMID:26116173

  2. 75 FR 61502 - Cooperative Agreement With the Pan American Health Organization for the Development of an...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-05

    ... HUMAN SERVICES Food and Drug Administration Cooperative Agreement With the Pan American Health... application to award a cooperative agreement to the Pan American Health Organization (PAHO) for the... efforts, such as the Pan American Network for Drug Regulatory Harmonization (PANDRH), the ICH...

  3. Agreement and Null Subjects in German L2 Development: New Evidence from Reaction-Time Experiments.

    ERIC Educational Resources Information Center

    Clahsen, Harald; Hong, Upyong

    1995-01-01

    Reports on reaction time experiments investigating subject-verb agreement and null subjects in 33 Korean learners of German and a control group of 20 German native speakers. Results found that the two phenomena do not covary in the Korean learners, indicating that properties of agreement and null subjects are acquired separately from one another.…

  4. 48 CFR 52.225-12 - Notice of Buy American Requirement-Construction Materials Under Trade Agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Notice of Buy American... CONTRACT CLAUSES Text of Provisions and Clauses 52.225-12 Notice of Buy American Requirement—Construction... Buy American Requirement—Construction Materials Under Trade Agreements (MAY 2014) (a)...

  5. 78 FR 57215 - Waiver of Requirement To Enter Into a Reciprocal Waiver of Claims Agreement With All Customers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-17

    ... Launch Activities, Notice of Proposed Rulemaking, 61 FR 38992, 39011 (Jul. 25, 1996). The FAA's... Waiver of Claims Agreement With All Customers, Notice of Waiver, 77 FR 63221 (Oct. 16, 2012). Issued in... NanoRacks, LLC, and NanoRacks locker insert and student experiments created under NASA's...

  6. 25 CFR 84.004 - Are there types of contracts and agreements that do not require Secretarial approval under this...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... law or regulation. See, for example, 25 CFR parts 152 (patents in fee, certificates or competency... are exempt from Secretarial approval under the terms of a corporate charter authorized by 25 U.S.C...-Governance Act, 25 U.S.C. 458aa. (i) Contracts or agreements that are subject to approval by the...

  7. 78 FR 70392 - Waiver of Requirement To Enter Into a Reciprocal Waiver of Claims Agreement With All Customers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-25

    ... Reciprocal Waiver of Claims Agreement With All Customers, Notice of Waiver, 77 FR 63221 (Oct. 16, 2012). \\7... Licensed Launch Activities, Notice of Proposed Rulemaking, 61 FR 38992, 39011 (Jul. 25, 1996). The FAA's... Customers for Orbital Sciences Corporation, Notice of Waiver, 78 FR 57215, 57216 (Sept. 17, 2013). The...

  8. Laser-communication cooperative research and development agreement between Air Force Phillips Lab and Ball Aerospace

    NASA Astrophysics Data System (ADS)

    Begley, David L.; Kehr, Robert L.; Sarto, Anthony W.; Casey, William; Coffelt, Everett L.; Goodrich, Alan; Thompson, William E.

    1997-04-01

    This paper presents an overview of a cooperative research and development program between Ball Aerospace and Technologies Corp. and the Air Force Phillips Laboratory for laser communications. This effort employs hardware and equipment originally developed to support the crosslinking between geostationary Defense Support Program surveillance satellites. This joint activity modifies the existing hardware for ground based demonstrations and simulations focuses at risk reduction for future applications and technology insertion into operational architectures meeting future commercial, civil, and DOD communications requirements. The ultimate goal of the program is to produce hardware for a near term flight demonstration. A brief overview of the capabilities of the existing hardware will be presented followed by a status of the development efforts and future plans.

  9. 76 FR 44956 - Solicitation for a Cooperative Agreement; Correctional Health Care Executive Curriculum Development

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-27

    ... National Institute of Corrections Solicitation for a Cooperative Agreement; Correctional Health Care... care, restorative therapy, health information management, and medical specialty services, including... personnel, correctional health care executives must judiciously contract with community-based facilities...

  10. European Union’s Public Fishing Access Agreements in Developing Countries

    PubMed Central

    Le Manach, Frédéric; Chaboud, Christian; Copeland, Duncan; Cury, Philippe; Gascuel, Didier; Kleisner, Kristin M.; Standing, André; Sumaila, U. Rashid; Zeller, Dirk; Pauly, Daniel

    2013-01-01

    The imperative to increase seafood supply while dealing with its overfished local stocks has pushed the European Union (EU) and its Member States to fish in the Exclusive Economic Zones of other countries through various types of fishing agreements for decades. Although European public fishing agreements are commented on regularly and considered to be transparent, this is the first global and historical study on the fee regime that governs them. We find that the EU has subsidized these agreements at an average of 75% of their cost (financial contribution agreed upon in the agreements), while private European business interests paid the equivalent of 1.5% of the value of the fish that was eventually landed. This raises questions of fisheries benefit-sharing and resource-use equity that the EU has the potential to address during the nearly completed reform of its Common Fisheries Policy. PMID:24312191

  11. 22 CFR Appendix A to Part 201 - Supplier's Certificate and Agreement With the Agency for International Development (AID 282)

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Agency for International Development (AID 282) A Appendix A to Part 201 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES AND PROCEDURES APPLICABLE TO COMMODITY TRANSACTIONS FINANCED BY USAID Pt. 201, App. A Appendix A to Part 201—Supplier's Certificate and Agreement With the Agency for...

  12. 22 CFR Appendix A to Part 201 - Supplier's Certificate and Agreement With the Agency for International Development (AID 282)

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Agency for International Development (AID 282) A Appendix A to Part 201 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES AND PROCEDURES APPLICABLE TO COMMODITY TRANSACTIONS FINANCED BY USAID Pt. 201, App. A Appendix A to Part 201—Supplier's Certificate and Agreement With the Agency for...

  13. 77 FR 63221 - Waiver of Requirement To Enter Into a Reciprocal Waiver of Claims Agreement With All Customers

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-16

    ... Requirements for Licensed Launch Activities, Notice of Proposed Rulemaking, 61 FR 38992, 39011 (Jul. 25, 1996... Rulemaking, 71 FR 62061 (Oct. 23, 2006). In the context of a customer assuming responsibility for its own.... Financial Responsibility Requirements for Licensed Launch Activities, Final Rule, 63 FR 45592, 45601-06...

  14. 42 CFR 403.910 - Delayed publication for payments made under product research or development agreements and...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 2 2014-10-01 2014-10-01 false Delayed publication for payments made under product research or development agreements and clinical investigations. 403.910 Section 403.910 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS SPECIAL PROGRAMS AND PROJECTS...

  15. Cooperative Research and Development Agreement between the California Air Resources Board and Lockheed Martin Idaho Technologies Company. Final report

    SciTech Connect

    Cole, G.H.

    1998-04-01

    This report summarizes the activities under a Cooperative Research and Development Agreement (CRADA) between Lockheed-Martin Idaho Technologies Company (LMITCO) and the California Air Resources Board (CARB). The activities were performed at the Idaho National Engineering and Environmental Laboratory (INEEL) between June 1995 and December 1997. Work under this agreement was concentrated in two task areas as defined in the California Air Resources Board`s contract number 94-908 having an approval date of June 9, 1995: Task 1--EV and HEV Vehicle Testing and Assessment and Task 4--Advanced Battery Testing.

  16. Participating in commercial space ventures: Introduction to NASA Centers for the Commercial Development of Space and the Cooperative Agreements Programs

    NASA Technical Reports Server (NTRS)

    1990-01-01

    In response to a Presidential directive, NASA has implemented a space policy which actively supports and encourages U.S. industry investment and participation in commercial space ventures. NASA's Office of Commercial Programs (OCP) has played a significant role in stimulating the growth of commercial space activity. Through a variety of programs, OCP encourages commercial interest and involvement in space endeavors by providing access to NASA resources and opportunities for the emerging space industry to reduce the technical, financial, and business risks associated with space-related activities. This manual describes NASA's Commercial Uses of Space Program and introduces participants to four major OCP Commercial programs: Technology Utilization (TU), Small Business Innovation Research (SBIR), Centers for the Commercial Development of Space Flight Agreement (CCDSFA), and Cooperative Agreements Programs. The objective of this manual is to assist U.S. industry identify and pursue the appropriate agreement for participation in a commercial space venture.

  17. 22 CFR 1509.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Cooperative agreement. 1509.620 Section 1509.620 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE... award. The term does not include cooperative research and development agreements as defined in 15...

  18. [Language development: psychosocial requirements for communication].

    PubMed

    Clemente, R A; Villanueva, L

    1999-02-01

    This work describes the social and psychological characteristics of attachment adults. These features are considered as sociopsychological prerequisites for the child language development. The focus is put on the so-called no formal education, suitable for these attachment adults who are involved affectively and emotionally. Some educational strategies to be practised at home are also presented. PMID:10778497

  19. Developing IVHM Requirements for Aerospace Systems

    NASA Technical Reports Server (NTRS)

    Rajamani, Ravi; Saxena, Abhinav; Kramer, Frank; Augustin, Mike; Schroeder, John B.; Goebel, Kai; Shao, Ginger; Roychoudhury, Indranil; Lin, Wei

    2013-01-01

    The term Integrated Vehicle Health Management (IVHM) describes a set of capabilities that enable sustainable and safe operation of components and subsystems within aerospace platforms. However, very little guidance exists for the systems engineering aspects of design with IVHM in mind. It is probably because of this that designers have to use knowledge picked up exclusively by experience rather than by established process. This motivated a group of leading IVHM practitioners within the aerospace industry under the aegis of SAE's HM-1 technical committee to author a document that hopes to give working engineers and program managers clear guidance on all the elements of IVHM that they need to consider before designing a system. This proposed recommended practice (ARP6883 [1]) will describe all the steps of requirements generation and management as it applies to IVHM systems, and demonstrate these with a "real-world" example related to designing a landing gear system. The team hopes that this paper and presentation will help start a dialog with the larger aerospace community and that the feedback can be used to improve the ARP and subsequently the practice of IVHM from a systems engineering point-of-view.

  20. Application Agreement and Integration Services

    NASA Technical Reports Server (NTRS)

    Driscoll, Kevin R.; Hall, Brendan; Schweiker, Kevin

    2013-01-01

    Application agreement and integration services are required by distributed, fault-tolerant, safety critical systems to assure required performance. An analysis of distributed and hierarchical agreement strategies are developed against the backdrop of observed agreement failures in fielded systems. The documented work was performed under NASA Task Order NNL10AB32T, Validation And Verification of Safety-Critical Integrated Distributed Systems Area 2. This document is intended to satisfy the requirements for deliverable 5.2.11 under Task 4.2.2.3. This report discusses the challenges of maintaining application agreement and integration services. A literature search is presented that documents previous work in the area of replica determinism. Sources of non-deterministic behavior are identified and examples are presented where system level agreement failed to be achieved. We then explore how TTEthernet services can be extended to supply some interesting application agreement frameworks. This document assumes that the reader is familiar with the TTEthernet protocol. The reader is advised to read the TTEthernet protocol standard [1] before reading this document. This document does not re-iterate the content of the standard.

  1. IT roadmap requirements for research and development

    SciTech Connect

    Geyer, Leslie J; Kinkead, Susan F

    2010-01-01

    In 2009, members representing the programmatic community of the Laboratory presented a request to the Information Architecture Steering Committee (IASC) to form a committee within the Information Architecture Program (IAP) to review and consider the needs of researchers. In response, a Research and Development Subteam under the Infrastructure Team was created. Members included volunteer representatives of groups performing research and development throughout the Laboratory. This paper represents the product of this review. The R&D computing environment has languished while Los Alamos has been very compliance driven for the past few years under a set of directives that have eliminated our ability to innovate and to push the envelope of R&D computing. The appeal for outside collaborations is rapidly becoming tarnished, as colleagues from outside the NNSA environment view our restrictions as increasingly oppressive. We are losing the ability to conduct cutting-edge research and losing money to competitors who are able to quickly react and pursue program dollars while we are still creating compliant but less than useful computing solutions. Research programs depend on collaboration, employees, foreign nationals, and frequent travel, including travel to foreign countries. Solutions need to facilitate these activities and be based on the risk that the activities actually pose to the infrastructure and data at LANL. Furthermore, when problems are solved, it is essential that the solutions are evaluated for cost/benefit to the programs, that programmatic impact is well identified, and that solutions have sufficient long term resource for collaborations.

  2. 78 FR 35321 - Solicitation for a Cooperative Agreement-IBM Instructional Guide and Assessment Tool Development

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE... Assessment Tool Development AGENCY: National Institute of Corrections, U.S. Department of Justice. ACTION... development of an instructional guide and assessment tool(s) that will help jail practitioners improve...

  3. 75 FR 1814 - Solicitation for a Cooperative Agreement-Curriculum Development: Training for Correctional...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-13

    ...The National Institute of Corrections' (NIC) Transition and Offender Workforce Development (T/OWD) and Academy Divisions are seeking applications for the development of a competency based, blended modality training curriculum that will provide Correctional Industries Directors with the knowledge, skills and abilities needed to set organizational priorities, identify strategic objectives,......

  4. 24 CFR 3288.110 - Alternative Process agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false Alternative Process agreements... HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME DISPUTE RESOLUTION PROGRAM Alternative Process in HUD-Administered States § 3288.110 Alternative Process agreements. (a) Required agreement. To use the...

  5. 24 CFR 3288.110 - Alternative Process agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 5 2014-04-01 2014-04-01 false Alternative Process agreements... HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME DISPUTE RESOLUTION PROGRAM Alternative Process in HUD-Administered States § 3288.110 Alternative Process agreements. (a) Required agreement. To use the...

  6. 22 CFR 1008.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Cooperative agreement. 1008.620 Section 1008.620 Foreign Relations INTER-AMERICAN FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL... term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  7. Brandon Research, Inc. Orthopedic Implant Cooperative Research and Development Agreement (CRADA) Final Report

    SciTech Connect

    Freeman, W.R.

    1999-04-22

    The project was a joint research effort between the U. S. Department of Energy's (DOE) Kansas City Plant (KCP) and Brandon Research, Inc. to develop ways to improve implants used for orthopedic surgery for joint replacement. The primary product produced by this study is design information, which may be used to develop implants that will improve long-term fixation and durability in the host bone environment.

  8. Constituencies, Clients, and Agreement in Rural Development: A Preliminary Statement for Project S-120.

    ERIC Educational Resources Information Center

    Voth, Donald E.

    Objective B of the Regional Project Statement for Project S-120 is "to determine perceptions toward development in activities, agency representatives, and clientele affected by organizational and agency activities". This paper addresses Objective B and presents a perspective which "suggests an answer to the inevitable 'so what' question when…

  9. 75 FR 52552 - Solicitation for a Cooperative Agreement-Curriculum Development: Implementing and Sustaining an...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-26

    .... The curriculum must adhere to NIC's Instructional Theory into Practice (ITIP) model, which applicants... should be developed using NIC's Instructional Theory into Practice (ITIP) model. The curriculum should... corrections supervisors and managers with the knowledge, skills, and abilities needed to model,...

  10. 78 FR 28866 - Cooperative Research and Development Agreement (CRADA) Opportunity With the Department of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-16

    ...The Department of Homeland Security Science and Technology Directorate (DHS S&T), through its Plum Island Animal Disease Center (PIADC), is seeking industry collaborators to aid DHS S&T in developing an ELISA diagnostic test that it capable of obtaining a U.S. regulatory license to detect antibodies to at least one of the Foot and Mouth Disease virus (FMDV) non-structural proteins (NSP): 3A,......

  11. Requirements Development for the NASA Advanced Engineering Environment (AEE)

    NASA Technical Reports Server (NTRS)

    Rogers, Eric; Hale, Joseph P.; Zook, Keith; Gowda, Sanjay; Salas, Andrea O.

    2003-01-01

    The requirements development process for the Advanced Engineering Environment (AEE) is presented. This environment has been developed to allow NASA to perform independent analysis and design of space transportation architectures and technologies. Given the highly collaborative and distributed nature of AEE, a variety of organizations are involved in the development, operations and management of the system. Furthermore, there are additional organizations involved representing external customers and stakeholders. Thorough coordination and effective communication is essential to translate desired expectations of the system into requirements. Functional, verifiable requirements for this (and indeed any) system are necessary to fulfill several roles. Requirements serve as a contractual tool, configuration management tool, and as an engineering tool, sometimes simultaneously. The role of requirements as an engineering tool is particularly important because a stable set of requirements for a system provides a common framework of system scope and characterization among team members. Furthermore, the requirements provide the basis for checking completion of system elements and form the basis for system verification. Requirements are at the core of systems engineering. The AEE Project has undertaken a thorough process to translate the desires and expectations of external customers and stakeholders into functional system-level requirements that are captured with sufficient rigor to allow development planning, resource allocation and system-level design, development, implementation and verification. These requirements are maintained in an integrated, relational database that provides traceability to governing Program requirements and also to verification methods and subsystem-level requirements.

  12. Perceived Requirements of MIS Curriculum Implementation in Bilingual Developing Countries

    ERIC Educational Resources Information Center

    Kabeil, Magdy M.

    2005-01-01

    This paper addresses additional requirements associated with implementing a standard curriculum of Management Information Systems (MIS) in bilingual developing countries where both students and workplace users speak English as a second language. In such countries, MIS graduates are required to develop bilingual computer applications and to…

  13. Developing sorbent standards for spill response: Effects of the Oil Pollution Act of 1990 and the Free Trade Agreement

    NASA Astrophysics Data System (ADS)

    Schrader, E. L.; Westover, E. S.

    1993-09-01

    For the past five years the Millsaps Sorbent Laboratory has been actively engaged in developing standards for initial and long-term oil spill remedial technologies. As a voting member of the American Society of Testing Materials (ASTM) F-20 Committee, Canadian General Standards Board, and the US Coast Guard Sorbents Task Force, the laboratory has been engaged in developing useful, pragmatic protocols for various chemical and physical sorbent and filtration technologies driven by the deadlines imposed by the Oil Pollution Act of 1990 (OPA 90). The “open border” approach to certification of technologies and products promulgated by the US/Canadian Free Trade Agreement has placed the US users and producers of such products and systems in a unique and tenuous position. Canadian standards and goals are grandfathered into the United States under this agreement and products have official US government certification based on Canadian regulations. This situation is unfavorable to the US domestic environment and economy for several specific scenarios. Included in these scenarios are: abundant warmwater zones and inland waters of the US versus Canada, the basic chemical variation between Canadian and US crude oils, the different generally accepted remediation technologies in the US versus Canadian, and the technology validation procedures prior to purchase inherent to both countries.

  14. Follow-On Cooperative Research and Development Agreement: MFIX to FLUENT Technology Transfer and Validation Studies Final Report

    SciTech Connect

    Madhava Syamlal; Guenther, Chris; O'Brien, Thomas J.; Benyahia, Sofiane; Shi, Shaoping

    2005-03-01

    This report summarizes the effort by NETL and Fluent on the Cooperative Research and Development Agreement No. 00-F039 signed in May 2000. The objective of the CRADA was to transfer technology from NETL's MFIX code into the commercial software FLUENT so as to increase the computational speed, accuracy, and utility of FLUENT. During the period of this CRADA MFIX was used to develop granular flow theories and used for simulating gas-solids chemical reactors. The FLUENT and MFIX predictions were compared with each other and with experimental data generated at NETL. The granular kinetic theory in FLUENT was improved as a result of this work, and a gas-solids reaction (ozone decomposition) was used as a test case for the gas-solids chemical reaction capability in FLUENT. Also, under a separate project, work has begun to transfer the coal combustion and gasification model in MFIX to FLUENT.

  15. 7 CFR 247.4 - Agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.4 Agreements. (a) What agreements are..., sex, or disability. (d) What is the duration of required agreements? Agreements between FNS and...

  16. 7 CFR 247.4 - Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.4 Agreements. (a) What agreements are..., sex, or disability. (d) What is the duration of required agreements? Agreements between FNS and...

  17. 7 CFR 247.4 - Agreements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.4 Agreements. (a) What agreements are..., sex, or disability. (d) What is the duration of required agreements? Agreements between FNS and...

  18. Agreement Execution Process Study: CRADAs and NF-WFO Agreements and the Speed of Business

    SciTech Connect

    Harrer, Bruce J.; Cejka, Cheryl L.; Macklin, Richard; Miksovic, Ann

    2011-02-01

    This report summarizes the findings of a study on the execution of Cooperative Research and Development Agreements (CRADAs) and Non-Federal Work for Others (NF-WFO) agreements across the U.S. Department of Energy (DOE) laboratory complex. The study provides quantitiative estimates of times required to negotiate and execute these agreements across the DOE complex. It identifies factors impacting on cycle times and describes best practicies used at various laboratories and site offices that reduce cycle times.

  19. JouleLabs Cooperative Research and Development Agreement: Cooperative Research and Development Final Report, CRADA Number CRD-08-00301

    SciTech Connect

    Bilello, D.

    2010-08-01

    The National Renewable Energy Laboratory (NREL) and Joule Labs Inc. (Joule Labs) will collaborate on creating a software platform for the development and distribution of renewable energy and energy efficiency analysis tools.

  20. Technology and development requirements for advanced coal conversion systems

    NASA Technical Reports Server (NTRS)

    1981-01-01

    A compendium of coal conversion process descriptions is presented. The SRS and MC data bases were utilized to provide information paticularly in the areas of existing process designs and process evaluations. Additional information requirements were established and arrangements were made to visit process developers, pilot plants, and process development units to obtain information that was not otherwise available. Plant designs, process descriptions and operating conditions, and performance characteristics were analyzed and requirements for further development identified and evaluated to determine the impact of these requirements on the process commercialization potential from the standpoint of economics and technical feasibility. A preliminary methodology was established for the comparative technical and economic assessment of advanced processes.

  1. 7 CFR Exhibit B to Subpart B of... - Grant Agreement (Public Bodies) for Site Development and/or Site Acquisition for Housing and/or...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...—Grant Agreement (Public Bodies) for Site Development and/or Site Acquisition for Housing and/or Public... costs of housing or public facilities. This Grant Agreement covers the following described real property... Copeland “Anti-Kick Back” Act (18 USC 874) as supplemented in Department of Labor regulations (29 CFR,...

  2. 7 CFR Exhibit B to Subpart B of... - Grant Agreement (Public Bodies) for Site Development and/or Site Acquisition for Housing and/or...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...—Grant Agreement (Public Bodies) for Site Development and/or Site Acquisition for Housing and/or Public... costs of housing or public facilities. This Grant Agreement covers the following described real property... Copeland “Anti-Kick Back” Act (18 USC 874) as supplemented in Department of Labor regulations (29 CFR,...

  3. 7 CFR Exhibit B to Subpart B of... - Grant Agreement (Public Bodies) for Site Development and/or Site Acquisition for Housing and/or...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...—Grant Agreement (Public Bodies) for Site Development and/or Site Acquisition for Housing and/or Public... costs of housing or public facilities. This Grant Agreement covers the following described real property... Copeland “Anti-Kick Back” Act (18 USC 874) as supplemented in Department of Labor regulations (29 CFR,...

  4. 7 CFR Exhibit B to Subpart B of... - Grant Agreement (Public Bodies) for Site Development and/or Site Acquisition for Housing and/or...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...—Grant Agreement (Public Bodies) for Site Development and/or Site Acquisition for Housing and/or Public... costs of housing or public facilities. This Grant Agreement covers the following described real property... Copeland “Anti-Kick Back” Act (18 USC 874) as supplemented in Department of Labor regulations (29 CFR,...

  5. Knowledge-based requirements analysis for automating software development

    NASA Technical Reports Server (NTRS)

    Markosian, Lawrence Z.

    1988-01-01

    We present a new software development paradigm that automates the derivation of implementations from requirements. In this paradigm, informally-stated requirements are expressed in a domain-specific requirements specification language. This language is machine-understable and requirements expressed in it are captured in a knowledge base. Once the requirements are captured, more detailed specifications and eventually implementations are derived by the system using transformational synthesis. A key characteristic of the process is that the required human intervention is in the form of providing problem- and domain-specific engineering knowledge, not in writing detailed implementations. We describe a prototype system that applies the paradigm in the realm of communication engineering: the prototype automatically generates implementations of buffers following analysis of the requirements on each buffer.

  6. Development and analysis of SCR requirements tables for system scenarios

    NASA Technical Reports Server (NTRS)

    Callahan, John R.; Morrison, Jeffery L.

    1995-01-01

    We describe the use of scenarios to develop and refine requirement tables for parts of the Earth Observing System Data and Information System (EOSDIS). The National Aeronautics and Space Administration (NASA) is developing EOSDIS as part of its Mission-To-Planet-Earth (MTPE) project to accept instrument/platform observation requests from end-user scientists, schedule and perform requested observations of the Earth from space, collect and process the observed data, and distribute data to scientists and archives. Current requirements for the system are managed with tools that allow developers to trace the relationships between requirements and other development artifacts, including other requirements. In addition, the user community (e.g., earth and atmospheric scientists), in conjunction with NASA, has generated scenarios describing the actions of EOSDIS subsystems in response to user requests and other system activities. As part of a research effort in verification and validation techniques, this paper describes our efforts to develop requirements tables from these scenarios for the EOSDIS Core System (ECS). The tables specify event-driven mode transitions based on techniques developed by the Naval Research Lab's (NRL) Software Cost Reduction (SCR) project. The SCR approach has proven effective in specifying requirements for large systems in an unambiguous, terse format that enhance identification of incomplete and inconsistent requirements. We describe development of SCR tables from user scenarios and identify the strengths and weaknesses of our approach in contrast to the requirements tracing approach. We also evaluate the capabilities of both approach to respond to the volatility of requirements in large, complex systems.

  7. Advance crew procedures development techniques: Procedures generation program requirements document

    NASA Technical Reports Server (NTRS)

    Arbet, J. D.; Benbow, R. L.; Hawk, M. L.

    1974-01-01

    The Procedures Generation Program (PGP) is described as an automated crew procedures generation and performance monitoring system. Computer software requirements to be implemented in PGP for the Advanced Crew Procedures Development Techniques are outlined.

  8. Ground Systems Development Environment (GSDE) interface requirements analysis

    NASA Technical Reports Server (NTRS)

    Church, Victor E.; Philips, John; Hartenstein, Ray; Bassman, Mitchell; Ruskin, Leslie; Perez-Davila, Alfredo

    1991-01-01

    A set of procedural and functional requirements are presented for the interface between software development environments and software integration and test systems used for space station ground systems software. The requirements focus on the need for centralized configuration management of software as it is transitioned from development to formal, target based testing. This concludes the GSDE Interface Requirements study. A summary is presented of findings concerning the interface itself, possible interface and prototyping directions for further study, and results of the investigation of the Cronus distributed applications environment.

  9. Advanced Extra-Vehicular Activity Pressure Garment Requirements Development

    NASA Technical Reports Server (NTRS)

    Ross, Amy; Aitchison, Lindsay; Rhodes, Richard

    2015-01-01

    The NASA Johnson Space Center advanced pressure garment technology development team is addressing requirements development for exploration missions. Lessons learned from the Z-2 high fidelity prototype development have reiterated that clear low-level requirements and verification methods reduce risk to the government, improve efficiency in pressure garment design efforts, and enable the government to be a smart buyer. The expectation is to provide requirements at the specification level that are validated so that their impact on pressure garment design is understood. Additionally, the team will provide defined verification protocols for the requirements. However, in reviewing exploration space suit high level requirements there are several gaps in the team's ability to define and verify related lower level requirements. This paper addresses the efforts in requirement areas such as mobility/fit/comfort and environmental protection (dust, radiation, plasma, secondary impacts) to determine the method by which the requirements can be defined and use of those methods for verification. Gaps exist at various stages. In some cases component level work is underway, but no system level effort has begun; in other cases no effort has been initiated to close the gap. Status of on-going efforts and potential approaches to open gaps are discussed.

  10. Section 508 Electronic Information Accessibility Requirements for Software Development

    NASA Technical Reports Server (NTRS)

    Ellis, Rebecca

    2014-01-01

    Section 508 Subpart B 1194.21 outlines requirements for operating system and software development in order to create a product that is accessible to users with various disabilities. This portion of Section 508 contains a variety of standards to enable those using assistive technology and with visual, hearing, cognitive and motor difficulties to access all information provided in software. The focus on requirements was limited to the Microsoft Windows® operating system as it is the predominant operating system used at this center. Compliance with this portion of the requirements can be obtained by integrating the requirements into the software development cycle early and by remediating issues in legacy software if possible. There are certain circumstances with software that may arise necessitating an exemption from these requirements, such as design or engineering software using dynamically changing graphics or numbers to convey information. These exceptions can be discussed with the Section 508 Coordinator and another method of accommodation used.

  11. Requirements Development for Interoperability Simulation Capability for Law Enforcement

    SciTech Connect

    Holter, Gregory M.

    2004-05-19

    The National Counterdrug Center (NCC) was initially authorized by Congress in FY 1999 appropriations to create a simulation-based counterdrug interoperability training capability. As the lead organization for Research and Analysis to support the NCC, the Pacific Northwest National Laboratory (PNNL) was responsible for developing the requirements for this interoperability simulation capability. These requirements were structured to address the hardware and software components of the system, as well as the deployment and use of the system. The original set of requirements was developed through a process of conducting a user-based survey of requirements for the simulation capability, coupled with an analysis of similar development efforts. The user-based approach ensured that existing concerns with respect to interoperability within the law enforcement community would be addressed. Law enforcement agencies within the designated pilot area of Cochise County, Arizona, were surveyed using interviews and ride-alongs during actual operations. The results of this survey were then accumulated, organized, and validated with the agencies to ensure the accuracy of the results. These requirements were then supplemented by adapting operational requirements from existing systems to ensure system reliability and operability. The NCC adopted a development approach providing incremental capability through the fielding of a phased series of progressively more capable versions of the system. This allowed for feedback from system users to be incorporated into subsequent revisions of the system requirements, and also allowed the addition of new elements as needed to adapt the system to broader geographic and geopolitical areas, including areas along the southwest and northwest U.S. borders. This paper addresses the processes used to develop and refine requirements for the NCC interoperability simulation capability, as well as the response of the law enforcement community to the use of

  12. 77 FR 43118 - Solicitation for a Cooperative Agreement-Development of a Series of Publications for the Evidence...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-23

    ...The National Institute of Corrections (NIC) Community Services Division is soliciting proposals from organizations, groups, or individuals to enter into a cooperative agreement with NIC for up to 18 months beginning in October 2012. Work under this cooperative agreement is part of a larger NIC initiative, Evidence-Based Decision Making (EBDM) in Local Criminal Justice Systems. Work under this......

  13. Ground Systems Development Environment (GSDE) interface requirements and prototyping plan

    NASA Technical Reports Server (NTRS)

    Church, Victor E.; Philips, John; Bassman, Mitchell; Williams, C.

    1990-01-01

    This report describes the data collection and requirements analysis effort of the Ground System Development Environment (GSDE) Interface Requirements study. It identifies potential problems in the interfaces among applications and processors in the heterogeneous systems that comprises the GSDE. It describes possible strategies for addressing those problems. It also identifies areas for further research and prototyping to demonstrate the capabilities and feasibility of those strategies and defines a plan for building the necessary software prototypes.

  14. Development of flight experiment task requirements. Volume 1: Summary

    NASA Technical Reports Server (NTRS)

    Hatterick, G. R.

    1972-01-01

    A study was conducted to develop the means to identify skills required of scientist passengers on advanced missions related to the space shuttle and RAM programs. The scope of the study was defined to include only the activities of on-orbit personnel which are directly related to, or required by, on-orbit experimentation and scientific investigations conducted on or supported by the shuttle orbiter. A program summary is presented which provides a description of the methodology developed, an overview of the activities performed during the study, and the results obtained through application of the methodology.

  15. Cooperative monitoring of regional security agreements

    SciTech Connect

    Pregenzer, A.L.; Vannoni, M.; Biringer, K.L.

    1996-11-01

    This paper argues that cooperative monitoring plays a critical role in the implementation of regional security agreements and confidence building measures. A framework for developing cooperative monitoring options is proposed and several possibilities for relating bilateral and regional monitoring systems to international monitoring systems are discussed. Three bilateral or regional agreements are analyzed briefly to illustrate different possibilities. These examples illustrate that the relationship of regional or bilateral arms control or security agreements to international agreements depends on a number of factors: the overlap of provisions between regional and international agreements; the degree of interest in a regional agreement among the international community; efficiency in implementing the agreement; and numerous political considerations. Given the importance of regional security to the international community, regions should be encouraged to develop their own infrastructure for implementing regional arms control and other security agreements. A regional infrastructure need not preclude participation in an international regime. On the contrary, establishing regional institutions for arms control and nonproliferation could result in more proactive participation of regional parties in developing solutions for regional and international problems, thereby strengthening existing and future international regimes. Possible first steps for strengthening regional infrastructures are identified and potential technical requirements are discussed.

  16. Higher Education Development Training. Agreement Between the United States of America and Indonesia. Signed at Jakarta, October 28, 1976. Treaties and Other International Acts Series 8759.

    ERIC Educational Resources Information Center

    Department of State, Washington, DC.

    An agreement for a loan granted by the United States to Indonesia through the Agency for International Development (AID) for higher education development training is described. The assistance to certain educational institutions is designed to assist in the financing of advanced training, upgrading and development of the faculties, administrations,…

  17. Structured interview for mild traumatic brain injury after military blast: inter-rater agreement and development of diagnostic algorithm.

    PubMed

    Walker, William C; Cifu, David X; Hudak, Anne M; Goldberg, Gary; Kunz, Richard D; Sima, Adam P

    2015-04-01

    The existing gold standard for diagnosing a suspected previous mild traumatic brain injury (mTBI) is clinical interview. But it is prone to bias, especially for parsing the physical versus psychological effects of traumatic combat events, and its inter-rater reliability is unknown. Several standardized TBI interview instruments have been developed for research use but have similar limitations. Therefore, we developed the Virginia Commonwealth University (VCU) retrospective concussion diagnostic interview, blast version (VCU rCDI-B), and undertook this cross-sectional study aiming to 1) measure agreement among clinicians' mTBI diagnosis ratings, 2) using clinician consensus develop a fully structured diagnostic algorithm, and 3) assess accuracy of this algorithm in a separate sample. Two samples (n = 66; n = 37) of individuals within 2 years of experiencing blast effects during military deployment underwent semistructured interview regarding their worst blast experience. Five highly trained TBI physicians independently reviewed and interpreted the interview content and gave blinded ratings of whether or not the experience was probably an mTBI. Paired inter-rater reliability was extremely variable, with kappa ranging from 0.194 to 0.825. In sample 1, the physician consensus prevalence of probable mTBI was 84%. Using these diagnosis ratings, an algorithm was developed and refined from the fully structured portion of the VCU rCDI-B. The final algorithm considered certain symptom patterns more specific for mTBI than others. For example, an isolated symptom of "saw stars" was deemed sufficient to indicate mTBI, whereas an isolated symptom of "dazed" was not. The accuracy of this algorithm, when applied against the actual physician consensus in sample 2, was almost perfect (correctly classified = 97%; Cohen's kappa = 0.91). In conclusion, we found that highly trained clinicians often disagree on historical blast-related mTBI determinations. A fully structured interview

  18. FGF signaling is required for initiation of feather placode development.

    PubMed

    Mandler, Markus; Neubüser, Annette

    2004-07-01

    Morphogenesis of hairs and feathers is initiated by an as yet unknown dermal signal that induces placode formation in the overlying ectoderm. To determine whether FGF signals are required for this process we over-expressed soluble versions of FGFR1 or FGFR2 in the skin of chicken embryos. This produced a complete failure of feather formation prior to any morphological or molecular signs of placode development. We further show that Fgf10 is expressed in the dermis of nascent feather primordia, and that anti-FGF10 antibodies block feather placode development in skin explants. In addition we show that FGF10 can induce expression of positive and negative regulators of feather development and can induce its own expression under conditions of low BMP signaling. Together these results demonstrate that FGF signaling is required for the initiation of feather placode development and implicate FGF10 as an early dermal signal involved in this process. PMID:15201222

  19. Supersonic HLFC: Potential benefits and technology development requirements

    NASA Technical Reports Server (NTRS)

    Neumann, Frank

    1992-01-01

    The viewgraphs and discussion of the potential benefits and technology development requirements of supersonic Hybrid Laminar Flow Control (HLFC) are reviewed. For the last three years, Boeing has performed studies on the application of laminar flow control to High Speed Civil Transport (HSCT) configurations. Large potential net benefits were identified for laminar flow control, even after accounting for the significant implementation penalties. However, the technical risks are high at this time, and an early, aggressive technology development program is required if laminar flow control (LFC) is to be incorporated in a year 2005 HSCT program. The benefits and required development effort are addressed. Of all the aerodynamic advances that are being considered for the HSCT, LFC has the largest potential for improving the supersonic lift drag ratio of a given configuration. The work accomplished to date, sponsored by NASA Langley, is summarized. This work includes studies on HLFC application to HSCT, cruise HLFC/low speed boundary layer control (BLC) compatibility, and impact of M 0.9 HLFC and high lift BLC. Requirements for production committments are listed. The need for a HSCT-HLFC Risk Reduction Program is addressed. Supersonic HLFC development planning and future applications are addressed. Laminar flow/high-lift integration is addressed.

  20. Nuclear thermal propulsion test facility requirements and development strategy

    NASA Technical Reports Server (NTRS)

    Allen, George C.; Warren, John; Clark, J. S.

    1991-01-01

    The Nuclear Thermal Propulsion (NTP) subpanel of the Space Nuclear Propulsion Test Facilities Panel evaluated facility requirements and strategies for nuclear thermal propulsion systems development. High pressure, solid core concepts were considered as the baseline for the evaluation, with low pressure concepts an alternative. The work of the NTP subpanel revealed that a wealth of facilities already exists to support NTP development, and that only a few new facilities must be constructed. Some modifications to existing facilities will be required. Present funding emphasis should be on long-lead-time items for the major new ground test facility complex and on facilities supporting nuclear fuel development, hot hydrogen flow test facilities, and low power critical facilities.

  1. Adoption of Requirements Engineering Practices in Malaysian Software Development Companies

    NASA Astrophysics Data System (ADS)

    Solemon, Badariah; Sahibuddin, Shamsul; Ghani, Abdul Azim Abd

    This paper presents exploratory survey results on Requirements Engineering (RE) practices of some software development companies in Malaysia. The survey attempted to identify patterns of RE practices the companies are implementing. Information required for the survey was obtained through a survey, mailed self-administered questionnaires distributed to project managers and software developers who are working at software development companies operated across the country. The results showed that the overall adoption of the RE practices in these companies is strong. However, the results also indicated that fewer companies in the survey have use appropriate CASE tools or software to support their RE process and practices, define traceability policies and maintain traceability manual in their projects.

  2. A software framework for developing measurement applications under variable requirements

    NASA Astrophysics Data System (ADS)

    Arpaia, Pasquale; Buzio, Marco; Fiscarelli, Lucio; Inglese, Vitaliano

    2012-11-01

    A framework for easily developing software for measurement and test applications under highly and fast-varying requirements is proposed. The framework allows the software quality, in terms of flexibility, usability, and maintainability, to be maximized. Furthermore, the development effort is reduced and finalized, by relieving the test engineer of development details. The framework can be configured for satisfying a large set of measurement applications in a generic field for an industrial test division, a test laboratory, or a research center. As an experimental case study, the design, the implementation, and the assessment inside the application to a measurement scenario of magnet testing at the European Organization for Nuclear Research is reported.

  3. Generic Safety Requirements for Developing Safe Insulin Pump Software

    PubMed Central

    Zhang, Yi; Jetley, Raoul; Jones, Paul L; Ray, Arnab

    2011-01-01

    Background The authors previously introduced a highly abstract generic insulin infusion pump (GIIP) model that identified common features and hazards shared by most insulin pumps on the market. The aim of this article is to extend our previous work on the GIIP model by articulating safety requirements that address the identified GIIP hazards. These safety requirements can be validated by manufacturers, and may ultimately serve as a safety reference for insulin pump software. Together, these two publications can serve as a basis for discussing insulin pump safety in the diabetes community. Methods In our previous work, we established a generic insulin pump architecture that abstracts functions common to many insulin pumps currently on the market and near-future pump designs. We then carried out a preliminary hazard analysis based on this architecture that included consultations with many domain experts. Further consultation with domain experts resulted in the safety requirements used in the modeling work presented in this article. Results Generic safety requirements for the GIIP model are presented, as appropriate, in parameterized format to accommodate clinical practices or specific insulin pump criteria important to safe device performance. Conclusions We believe that there is considerable value in having the diabetes, academic, and manufacturing communities consider and discuss these generic safety requirements. We hope that the communities will extend and revise them, make them more representative and comprehensive, experiment with them, and use them as a means for assessing the safety of insulin pump software designs. One potential use of these requirements is to integrate them into model-based engineering (MBE) software development methods. We believe, based on our experiences, that implementing safety requirements using MBE methods holds promise in reducing design/implementation flaws in insulin pump development and evolutionary processes, therefore improving

  4. Development of Airport Surface Required Navigation Performance (RNP)

    NASA Technical Reports Server (NTRS)

    Cassell, Rick; Smith, Alex; Hicok, Dan

    1999-01-01

    The U.S. and international aviation communities have adopted the Required Navigation Performance (RNP) process for defining aircraft performance when operating the en-route, approach and landing phases of flight. RNP consists primarily of the following key parameters - accuracy, integrity, continuity, and availability. The processes and analytical techniques employed to define en-route, approach and landing RNP have been applied in the development of RNP for the airport surface. To validate the proposed RNP requirements several methods were used. Operational and flight demonstration data were analyzed for conformance with proposed requirements, as were several aircraft flight simulation studies. The pilot failure risk component was analyzed through several hypothetical scenarios. Additional simulator studies are recommended to better quantify crew reactions to failures as well as additional simulator and field testing to validate achieved accuracy performance, This research was performed in support of the NASA Low Visibility Landing and Surface Operations Programs.

  5. HLLV avionics requirements study and electronic filing system database development

    NASA Technical Reports Server (NTRS)

    1994-01-01

    This final report provides a summary of achievements and activities performed under Contract NAS8-39215. The contract's objective was to explore a new way of delivering, storing, accessing, and archiving study products and information and to define top level system requirements for Heavy Lift Launch Vehicle (HLLV) avionics that incorporate Vehicle Health Management (VHM). This report includes technical objectives, methods, assumptions, recommendations, sample data, and issues as specified by DPD No. 772, DR-3. The report is organized into two major subsections, one specific to each of the two tasks defined in the Statement of Work: the Index Database Task and the HLLV Avionics Requirements Task. The Index Database Task resulted in the selection and modification of a commercial database software tool to contain the data developed during the HLLV Avionics Requirements Task. All summary information is addressed within each task's section.

  6. Quality functions for requirements engineering in system development methods.

    PubMed

    Johansson, M; Timpka, T

    1996-01-01

    Based on a grounded theory framework, this paper analyses the quality characteristics for methods to be used for requirements engineering in the development of medical decision support systems (MDSS). The results from a Quality Function Deployment (QFD) used to rank functions connected to user value and a focus group study were presented to a validation focus group. The focus group studies take advantage of a group process to collect data for further analyses. The results describe factors considered by the participants as important in the development of methods for requirements engineering in health care. Based on the findings, the content which, according to the user a MDSS method should support is established. PMID:8947891

  7. Cooperative monitoring of regional security agreements

    SciTech Connect

    Pregenzer, A.L.; Vannoni, M.; Biringer, K.L.

    1995-08-01

    This paper argues that cooperative monitoring plays a critical role in the implementation of regional security agreements and confidence building measures. A framework for developing cooperative monitoring options is proposed and several possibilities for relating bilateral and regional monitoring systems to international monitoring systems are discussed. Three bilateral or regional agreements are analyzed briefly to illustrate different possibilities: (1) the demilitarization of the Sinai region between Israel and Egypt in the 1970s; (2) the 1991 quadripartite agreement for monitoring nuclear facilities among Brazil, Argentina, The Argentine-Brazilian Agency for Accounting and Control of Nuclear Materials and the International Atomic Energy Agency; and (3) a bilateral Open Skies agreement between Hungary and Romania in 1991. These examples illustrate that the relationship of regional or bilateral arms control or security agreements to international agreements depends on a number of factors: the overlap of provisions between regional and international agreements; the degree of interest in a regional agreement among the international community; efficiency in implementing the agreement; and numerous political considerations.Given the importance of regional security to the international community, regions should be encouraged to develop their own infrastructure for implementing regional arms control and other security agreements. A regional infrastructure need not preclude participation in an international regime. On the contrary, establishing regional institutions for arms control and nonproliferation could result in more proactive participation of regional parties in developing solutions for regional and international problems, thereby strengthening existing and future international regimes. Possible first steps for strengthening regional infrastructures are identified and potential technical requirements are discussed.

  8. The actual development of European Aviation Safety Requirements in Aviation Medicine: Prospects of Future EASA Requirements

    PubMed Central

    Siedenburg, J

    2009-01-01

    Common Rules for Aviation Safety had been developed under the aegis of the Joint Aviation Authorities in the 1990ies. In 2002 the Basic Regulation 1592/2002 was the founding document of a new entity, the European Aviation Safety Agency. Areas of activity were Certification and Maintenance of aircraft. On 18 March the new Basic Regulation 216/2008, repealing the original Basic Regulation was published and applicable from 08 April on. The included Essential Requirements extended the competencies of EASA inter alia to Pilot Licensing and Flight Operations. The future aeromedical requirements will be included as Annex II in another Implementing Regulation on Personnel Licensing. The detailed provisions will be published as guidance material. The proposals for these provisions have been published on 05 June 2008 as NPA 2008- 17c. After public consultation, processing of comments and final adoption the new proposals may be applicable form the second half of 2009 on. A transition period of four year will apply. Whereas the provisions are based on Joint Awiation Requirement - Flight Crew Licensing (JAR-FCL) 3, a new Light Aircraft Pilot Licence (LAPL) project and the details of the associated medical certification regarding general practitioners will be something new in aviation medicine. This paper consists of 6 sections. The introduction outlines the idea of international aviation safety. The second section describes the development of the Joint Aviation Authorities (JAA), the first step to common rules for aviation safety in Europe. The third section encompasses a major change as next step: the foundation of the European Aviation Safety Agency (EASA) and the development of its rules. In the following section provides an outline of the new medical requirements. Section five emphasizes the new concept of a Leisure Pilot Licence. The last section gives an outlook on ongoing rulemaking activities and the opportunities of the public to participate in them. PMID:19561781

  9. TWRS privatization Phase I site development design requirements document

    SciTech Connect

    Shord, A.L.

    1997-01-21

    The DOE-RL is pursuing a strategy of hiring private contractors for treatment of Hanford Site tank wastes. This strategy is called privatization and includes design, permitting,construction, operation, and deactivation of facilities for tank waste treatment. The TWRS Privatization Infrastructure Project consists of several sub- projects which will provide key services needed to support the privatization mission. This document identifies the design requirements for the site development sub-project, including construction, power, water, and road modifications. It will be used in development of the project`s conceptual design.

  10. Research requirements for development of improved helicopter rotor efficiency

    NASA Technical Reports Server (NTRS)

    Davis, S. J.

    1976-01-01

    The research requirements for developing an improved-efficiency rotor for a civil helicopter are documented. The various design parameters affecting the hover and cruise efficiency of a rotor are surveyed, and the parameters capable of producing the greatest potential improvement are identified. Research and development programs to achieve these improvements are defined, and estimated costs and schedules are presented. Interaction of the improved efficiency rotor with other technological goals for an advanced civil helicopter is noted, including its impact on engine noise, hover and cruise performance, one-engine-inoperative hover capability, and maintenance and reliability.

  11. Developing Tools and Technologies to Meet MSR Planetary Protection Requirements

    NASA Technical Reports Server (NTRS)

    Lin, Ying

    2013-01-01

    This paper describes the tools and technologies that need to be developed for a Caching Rover mission in order to meet the overall Planetary Protection requirements for future Mars Sample Return (MSR) campaign. This is the result of an eight-month study sponsored by the Mars Exploration Program Office. The goal of this study is to provide a future MSR project with a focused technology development plan for achieving the necessary planetary protection and sample integrity capabilities for a Mars Caching Rover mission.

  12. Mask substrate requirements and development for extreme ultraviolet lithography (EUVL)

    SciTech Connect

    Hector, S D; Shell, M; Taylor, J S; Tong, W M

    1999-09-28

    The mask is deemed one of the areas that require significant research and development in EUVL. Silicon wafers will be used for mask substrates for an alpha-class EUVL exposure tool due to their low-defect levels and high quality surface finish. However, silicon has a large coefficient of thermal expansion that leads to unacceptable image distortion due to absorption of EUV light. A low thermal expansion glass or glass-ceramic is likely to be required in order to meet error budgets for the 70nm node and beyond. Since EUVL masks are used in reflection, they are coated with multilayers prior to patterning. Surface imperfections, such as polishing marks, particles, scratches, or digs, are potential nucleation sites for defects in the multilayer coating, which could result in the printed defects. Therefore we are accelerating developments in the defect reduction and surface finishing of low thermal expansion mask substrates in order to understand long-term issues in controlling printable defects, and to establish the infrastructure for supplying masks. In this paper, we explain the technical requirements for EUVL mask substrates and describe our efforts in establishing a SEMI standard for EUVL masks. We will also report on the early progress of our suppliers in producing low thermal-expansion mask substrates for our development activities.

  13. Differential requirement for Nfil3 during NK cell development.

    PubMed

    Seillet, Cyril; Huntington, Nicholas D; Gangatirkar, Pradnya; Axelsson, Elin; Minnich, Martina; Brady, Hugh J M; Busslinger, Meinrad; Smyth, Mark J; Belz, Gabrielle T; Carotta, Sebastian

    2014-03-15

    NK cells can be grouped into distinct subsets that are localized to different organs and exhibit a different capacity to secrete cytokines and mediate cytotoxicity. Despite these hallmarks that reflect tissue-specific specialization in NK cells, little is known about the factors that control the development of these distinct subsets. The basic leucine zipper transcription factor Nfil3 (E4bp4) is essential for bone marrow-derived NK cell development, but it is not clear whether Nfil3 is equally important for all NK cell subsets or how it induces NK lineage commitment. In this article, we show that Nfil3 is required for the formation of Eomes-expressing NK cells, including conventional medullary and thymic NK cells, whereas TRAIL(+) Eomes(-) NK cells develop independently of Nfil3. Loss of Nfil3 during the development of bone marrow-derived NK cells resulted in reduced expression of Eomes and, conversely, restoration of Eomes expression in Nfil3(-/-) progenitors rescued NK cell development and maturation. Collectively, these findings demonstrate that Nfil3 drives the formation of mature NK cells by inducing Eomes expression and reveal the differential requirements of NK cell subsets for Nfil3. PMID:24532575

  14. Canadian seismic agreement

    SciTech Connect

    Wetmiller, R.J.; Lyons, J.A.; Shannon, W.E.; Munro, P.S.; Thomas, J.T.; Andrew, M.D.; Lamontagne, M.; Wong, C., Anglin, F.M.; Plouffe, M.; Lapointe, S.P.; Adams, J.; Drysdale, J.A. . Geophysics Div.)

    1990-04-01

    This is the twenty-first progress report under the agreement entitled Canadian Seismic Agreement between the US Nuclear Regulatory Commission (NRC) and the Canadian Commercial Corporation. Activities undertaken by the Geophysics Division of the Geological Survey of Canada (GD/GSC) during the period from July 01, 1988 to June 30, 1989 and supported in part by the NRC agreement are described below under four headings; Eastern Canada Telemetred Network and local network developments, Datalab developments, strong motion network developments and earthquake activity. In this time period eastern Canada experienced its largest earthquake in over 50 years. This earthquake, which has been christened the Saguenay earthquake, has provided a wealth of new data pertinent to earthquake engineering studies in eastern North America and is the subject of many continuing studies, which are presently being carried out at GD and elsewhere. 41 refs., 21 figs., 7 tabs.

  15. Canadian Seismic Agreement

    SciTech Connect

    Wetmiller, R.J.; Lyons, J.A.; Shannon, W.E.; Munro, P.S.; Thomas, J.T.; Andrew, M.D.; Lapointe, S.P.; Lamontagne, M.; Wong, C.; Anglin, F.M.; Adams, J.; Cajka, M.G.; McNeil, W.; Drysdale, J.A. )

    1992-05-01

    This is a progress report of work carried out under the terms of a research agreement entitled the Canadian Seismic Agreement'' between the US Nuclear Regulatory Commission (USNRC), the Canadian Commercial Corporation and the Geophysics Division of the Geological Survey of Canada (GD/GSC) during the period from July 01, 1989 to June 30, 1990. The Canadian Seismic Agreement'' supports generally the operation of various seismograph stations in eastern Canada and the collection and analysis of earthquake data for the purpose of mitigating seismic hazards in eastern Canada and the northeastern US. The specific activities carried out in this one-year period are summarized below under four headings; Eastern Canada Telemetred Network and local network developments, Datalab developments, strong-motion network developments and earthquake activity. During this period the first surface fault unequivocably determined to have accompanied a historic earthquake in eastern North America, occurred in northern Quebec.

  16. FFTF Authorization Agreement

    SciTech Connect

    DAUTEL, W.A.

    2000-09-25

    The purpose of the Authorization Agreement is to serve as a mechanism whereby the U.S. Department of Energy, Richland Operations Office (RL) and Fluor Hanford (FH) jointly clarify and agree to key conditions for conducting work safely and efficiently in the Fast Flux Test Facility (FFTF). Work must be accomplished in a manner that achieves high levels of quality while protecting the environment and the safety and health of workers and the public, and complying with applicable contractual and regulatory requirements. It is the intent of this Agreement to address those items of significant importance in establishing and supporting the FFTF Authorization Envelope, but this Agreement in no way alters the terms and conditions of the Project Hanford Management Contract (PHMC), Contract Number DE-AC06-96RL13200.

  17. Basic Requirements for Systems Software Research and Development

    NASA Technical Reports Server (NTRS)

    Kuszmaul, Chris; Nitzberg, Bill

    1996-01-01

    Our success over the past ten years evaluating and developing advanced computing technologies has been due to a simple research and development (R/D) model. Our model has three phases: (a) evaluating the state-of-the-art, (b) identifying problems and creating innovations, and (c) developing solutions, improving the state- of-the-art. This cycle has four basic requirements: a large production testbed with real users, a diverse collection of state-of-the-art hardware, facilities for evalua- tion of emerging technologies and development of innovations, and control over system management on these testbeds. Future research will be irrelevant and future products will not work if any of these requirements is eliminated. In order to retain our effectiveness, the numerical aerospace simulator (NAS) must replace out-of-date production testbeds in as timely a fashion as possible, and cannot afford to ignore innovative designs such as new distributed shared memory machines, clustered commodity-based computers, and multi-threaded architectures.

  18. Mining Agreements with Indian Tribes

    ERIC Educational Resources Information Center

    Luebben, Tom

    1976-01-01

    The article discusses aspects of negotiating agreements for exploration, development, and mining of hard minerals on Indian Reservations. The agreements discussed are typical of copper agreements, but the general points under discussion are applicable to most hard minerals except for uranium, coal, and oil which are substantially different.…

  19. Requirements and Techniques for Developing and Measuring Simulant Materials

    NASA Technical Reports Server (NTRS)

    Rickman, Doug; Owens, Charles; Howard, Rick

    2006-01-01

    The 1989 workshop report entitled Workshop on Production and Uses of Simulated Lunar Materials and the Lunar Regolith Simulant Materials: Recommendations for Standardization, Production, and Usage, NASA Technical Publication identify and reinforced a need for a set of standards and requirements for the production and usage of the lunar simulant materials. As NASA need prepares to return to the moon, a set of requirements have been developed for simulant materials and methods to produce and measure those simulants have been defined. Addressed in the requirements document are: 1) a method for evaluating the quality of any simulant of a regolith, 2) the minimum Characteristics for simulants of lunar regolith, and 3) a method to produce lunar regolith simulants needed for NASA's exploration mission. A method to evaluate new and current simulants has also been rigorously defined through the mathematics of Figures of Merit (FoM), a concept new to simulant development. A single FoM is conceptually an algorithm defining a single characteristic of a simulant and provides a clear comparison of that characteristic for both the simulant and a reference material. Included as an intrinsic part of the algorithm is a minimum acceptable performance for the characteristic of interest. The algorithms for the FoM for Standard Lunar Regolith Simulants are also explicitly keyed to a recommended method to make lunar simulants.

  20. A software framework for developing measurement applications under variable requirements.

    PubMed

    Arpaia, Pasquale; Buzio, Marco; Fiscarelli, Lucio; Inglese, Vitaliano

    2012-11-01

    A framework for easily developing software for measurement and test applications under highly and fast-varying requirements is proposed. The framework allows the software quality, in terms of flexibility, usability, and maintainability, to be maximized. Furthermore, the development effort is reduced and finalized, by relieving the test engineer of development details. The framework can be configured for satisfying a large set of measurement applications in a generic field for an industrial test division, a test laboratory, or a research center. As an experimental case study, the design, the implementation, and the assessment inside the application to a measurement scenario of magnet testing at the European Organization for Nuclear Research is reported. PMID:23206094

  1. Ground Systems Development Environment (GSDE) interface requirements analysis: Operations scenarios

    NASA Technical Reports Server (NTRS)

    Church, Victor E.; Phillips, John

    1991-01-01

    This report is a preliminary assessment of the functional and data interface requirements to the link between the GSDE GS/SPF (Amdahl) and the Space Station Control Center (SSCC) and Space Station Training Facility (SSTF) Integration, Verification, and Test Environments (IVTE's). These interfaces will be involved in ground software development of both the control center and the simulation and training systems. Our understanding of the configuration management (CM) interface and the expected functional characteristics of the Amdahl-IVTE interface is described. A set of assumptions and questions that need to be considered and resolved in order to complete the interface functional and data requirements definitions are presented. A listing of information items defined to describe software configuration items in the GSDE CM system is included. It also includes listings of standard reports of CM information and of CM-related tools in the GSDE.

  2. Developing Earth Observations Requirements for Global Agricultural Monitoring

    NASA Astrophysics Data System (ADS)

    Whitcraft, A. K.; Becker-Reshef, I.; Vermote, E.; Justice, C. O.

    2013-12-01

    Recognizing the dynamic nature of agricultural cultivation both within and between years and across the globe, the Group on Earth Observations (GEO) is developing an agricultural monitoring (GEO-GLAM) system with the goal of enhancing the availability and use of satellite and in situ Earth observations (EO) for the generation of timely and accurate information on national, regional, and global food supply. One of the key components of the GEO-GLAM system is the coordination of satellite observations so as to ensure sufficient and appropriate data volume and quality for agricultural monitoring. Therefore, it is essential that we develop EO requirements which articulate in a spatially explicit way where, when, how frequently, and at what spatial resolution satellite imagery must be acquired to meet the needs of a variety of agricultural monitoring applications. Accordingly, best-available cropland location information ('where?') in conjunction with ten years of MODIS surface reflectance data have been used to characterize the timing and duration of the agricultural growing season ('when?') in the form of agricultural growing season calendars (GSCs) for all major agricultural areas of the Earth. With respect to temporal resolution, we must first identify the frequency with which we require imagery inputs for monitoring applications such as crop condition, crop type, crop yield estimation, and planted and harvested area estimation. Members of the GEO Agriculture Monitoring Community of Practice - a group of international scientists - have combined their knowledge and expertise to articulate these general requirements. Second, we must determine how cloud cover impacts the ability of optical sensing systems to meet these established temporal resolution requirements. To this end, MODIS Terra (morning; 2000-2011) and Aqua (afternoon; 2002-2011) observations have been analyzed to derive probabilities of a cloud free clear view at different times of day throughout the

  3. 7 CFR Exhibit B to Subpart B of... - Grant Agreement (Public Bodies) for Site Development and/or Site Acquisition for Housing and/or...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 13 2013-01-01 2013-01-01 false Grant Agreement (Public Bodies) for Site Development and/or Site Acquisition for Housing and/or Public Facilities and/or Services B Exhibit B to Subpart B of Part 1948 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE,...

  4. Miz1 Is Required for Early Embryonic Development during Gastrulation

    PubMed Central

    Adhikary, Sovana; Peukert, Karen; Karsunky, Holger; Beuger, Vincent; Lutz, Werner; Elsässer, Hans-Peter; Möröy, Tarik; Eilers, Martin

    2003-01-01

    Miz1 is a member of the POZ domain/zinc finger transcription factor family. In vivo, Miz1 forms a complex with the Myc oncoprotein and recruits Myc to core promoter elements. Myc represses transcription through Miz1 binding sites. We now show that the Miz1 gene is ubiquitously expressed during mouse embryogenesis. In order to elucidate the physiological function of Miz1, we have deleted the mouse Miz1 gene by homologous recombination. Miz1+/− mice are indistinguishable from wild-type animals; in contrast, Miz1−/− embryos are not viable. They are severely retarded in early embryonic development and do not undergo normal gastrulation. Expression of Goosecoid and Brachyury is detectable in Miz1−/− embryos, suggesting that Miz1 is not required for signal transduction by Nodal. Expression of p21Cip1, a target gene of Miz1 is unaltered; in contrast, expression of p57Kip2, another target gene of Miz1 is absent in Miz1−/− embryos. Miz1−/− embryos succumb to massive apoptosis of ectodermal cells around day 7.5 of embryonic development. Our results show that Miz1 is required for early embryonic development during gastrulation. PMID:14560010

  5. Software requirements: Guidance and control software development specification

    NASA Technical Reports Server (NTRS)

    Withers, B. Edward; Rich, Don C.; Lowman, Douglas S.; Buckland, R. C.

    1990-01-01

    The software requirements for an implementation of Guidance and Control Software (GCS) are specified. The purpose of the GCS is to provide guidance and engine control to a planetary landing vehicle during its terminal descent onto a planetary surface and to communicate sensory information about that vehicle and its descent to some receiving device. The specification was developed using the structured analysis for real time system specification methodology by Hatley and Pirbhai and was based on a simulation program used to study the probability of success of the 1976 Viking Lander missions to Mars. Three versions of GCS are being generated for use in software error studies.

  6. 14 CFR 437.35 - Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... TRANSPORTATION LICENSING EXPERIMENTAL PERMITS Requirements to Obtain an Experimental Permit Operational Safety Documentation § 437.35 Agreements. An applicant must enter into the agreements required by § 437.63, and...

  7. 14 CFR 437.35 - Agreements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... TRANSPORTATION LICENSING EXPERIMENTAL PERMITS Requirements to Obtain an Experimental Permit Operational Safety Documentation § 437.35 Agreements. An applicant must enter into the agreements required by § 437.63, and...

  8. Requirements for the adenylyl cyclases in the development of Dictyostelium.

    PubMed

    Anjard, C; Söderbom, F; Loomis, W F

    2001-09-01

    It has been suggested that all intracellular signaling by cAMP during development of Dictyostelium is mediated by the cAMP-dependent protein kinase, PKA, since cells carrying null mutations in the acaA gene that encodes adenylyl cyclase can develop so as to form fruiting bodies under some conditions if PKA is made constitutive by overexpressing the catalytic subunit. However, a second adenylyl cyclase encoded by acrA has recently been found that functions in a cell autonomous fashion during late development. We have found that expression of a modified acaA gene rescues acrA- mutant cells indicating that the only role played by ACR is to produce cAMP. To determine whether cells lacking both adenylyl cyclase genes can develop when PKA is constitutive we disrupted acrA in a acaA- PKA-C(over) strain. When developed at high cell densities, acrA- acaA- PKA-C(over) cells form mounds, express cell type-specific genes at reduced levels and secrete cellulose coats but do not form fruiting bodies or significant numbers of viable spores. Thus, it appears that synthesis of cAMP is required for spore differentiation in Dictyostelium even if PKA activity is high. PMID:11566867

  9. Advanced Environmental Monitoring and Control Program: Technology Development Requirements

    NASA Technical Reports Server (NTRS)

    Jan, Darrell (Editor); Seshan, Panchalam (Editor); Ganapathi, Gani (Editor); Schmidt, Gregory (Editor); Doarn, Charles (Editor)

    1996-01-01

    Human missions in space, from the International Space Station on towards potential human exploration of the moon, Mars and beyond into the solar system, will require advanced systems to maintain an environment that supports human life. These systems will have to recycle air and water for many months or years at a time, and avoid harmful chemical or microbial contamination. NASA's Advanced Environmental Monitoring and Control program has the mission of providing future spacecraft with advanced, integrated networks of microminiaturized sensors to accurately determine and control the physical, chemical and biological environment of the crew living areas. This document sets out the current state of knowledge for requirements for monitoring the crew environment, based on (1) crew health, and (2) life support monitoring systems. Both areas are updated continuously through research and space mission experience. The technologies developed must meet the needs of future life support systems and of crew health monitoring. These technologies must be inexpensive and lightweight, and use few resources. Using these requirements to continue to push the state of the art in miniaturized sensor and control systems will produce revolutionary technologies to enable detailed knowledge of the crew environment.

  10. Development of photovoltaic array and module safety requirements

    NASA Technical Reports Server (NTRS)

    1982-01-01

    Safety requirements for photovoltaic module and panel designs and configurations likely to be used in residential, intermediate, and large-scale applications were identified and developed. The National Electrical Code and Building Codes were reviewed with respect to present provisions which may be considered to affect the design of photovoltaic modules. Limited testing, primarily in the roof fire resistance field was conducted. Additional studies and further investigations led to the development of a proposed standard for safety for flat-plate photovoltaic modules and panels. Additional work covered the initial investigation of conceptual approaches and temporary deployment, for concept verification purposes, of a differential dc ground-fault detection circuit suitable as a part of a photovoltaic array safety system.

  11. Eyelid Closure in Embryogenesis Is Required for Ocular Adnexa Development

    PubMed Central

    Meng, Qinghang; Mongan, Maureen; Carreira, Vinicius; Kurita, Hisaka; Liu, Chia-yang; Kao, Winston W.-Y.; Xia, Ying

    2014-01-01

    Purpose. Mammalian eye development requires temporary fusion of the upper and lower eyelids in embryogenesis. Failure of lid closure in mice leads to an eye open at birth (EOB) phenotype. Many genetic mutant strains develop this phenotype and studies of the mutants lead to a better understanding of the signaling mechanisms of morphogenesis. The present study investigates the roles of lid closure in eye development. Methods. Seven mutant mouse strains were generated by different gene ablation strategies that inactivated distinct signaling pathways. These mice, including systemic ablation of Map3k1 and Dkk2, ocular surface epithelium (OSE) knockout of c-Jun and Egfr, conditional knockout of Shp2 in stratified epithelium (SE), as well as the Map3k1/Jnk1 and Map3k1/Rhoa compound mutants, all exhibited defective eyelid closure. The embryonic and postnatal eyes in these mice were characterized by histology and immunohistochemistry. Results. Some eye abnormalities, such as smaller lens in the Map3k1-null mice and Harderian gland hypoplasia in the Dkk2-null mice, appeared to be mutant strain–specific, whereas other abnormalities were seen in all mutants examined. The common defects included corneal erosion/ulceration, meibomian gland hypoplasia, truncation of the eyelid tarsal muscles, failure of levator palpebrae superioris (LPS) extension into the upper eyelid and misplacement of the inferior oblique (IO) muscle and inferior rectus (IR) muscle. The muscle defects were traced to the prenatal fetuses. Conclusions. In addition to providing a protective barrier for the ocular surface, eyelid closure in embryogenesis is required for the development of ocular adnexa, including eyelid and extraocular muscles. PMID:25377219

  12. Linking Goal-Oriented Requirements and Model-Driven Development

    NASA Astrophysics Data System (ADS)

    Pastor, Oscar; Giachetti, Giovanni

    In the context of Goal-Oriented Requirement Engineering (GORE) there are interesting modeling approaches for the analysis of complex scenarios that are oriented to obtain and represent the relevant requirements for the development of software products. However, the way to use these GORE models in an automated Model-Driven Development (MDD) process is not clear, and, in general terms, the translation of these models into the final software products is still manually performed. Therefore, in this chapter, we show an approach to automatically link GORE models and MDD processes, which has been elaborated by considering the experience obtained from linking the i * framework with an industrially applied MDD approach. The linking approach proposed is formulated by means of a generic process that is based on current modeling standards and technologies in order to facilitate its application for different MDD and GORE approaches. Special attention is paid to how this process generates appropriate model transformation mechanisms to automatically obtain MDD conceptual models from GORE models, and how it can be used to specify validation mechanisms to assure the correct model transformations.

  13. Manned remote work station development article. Volume 1, book 1: Flight article requirements. Appendix A: Mission requirements

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The requirements for several configurations of flight articles are presented. These requirements provide the basis to design manned remote work station development test articles and establish tests and simulation objectives for the resolution of development issues. Mission system and subsystem requirements for four MRWS configurations included: open cherry picker; closed cherry picker; crane turret; and free flyer.

  14. Developing an operational rangeland water requirement satisfaction index

    USGS Publications Warehouse

    Senay, G.B.; Verdin, J.P.; Rowland, J.

    2011-01-01

    Developing an operational water requirement satisfaction index (WRSI) for range-land monitoring is an important goal of the famine early warning systems network. An operational WRSI has been developed for crop monitoring, but until recently a comparable WRSI for rangeland was not successful because of the extremely poor performance of the index when based on published crop coefficients (Kc) for rangelands. To improve the rangeland WRSI, we developed a simple calibration technique that adjusts the Kc values for rangeland monitoring using long-term rainfall distribution and reference evapotranspiration data. The premise for adjusting the Kc values is based on the assumption that a viable rangeland should exhibit above-average WRSI (values >80%) during a normal year. The normal year was represented by a median dekadal rainfall distribution (satellite rainfall estimate from 1996 to 2006). Similarly, a long-term average for potential evapotranspiration was used as input to the famine early warning systems network WRSI model in combination with soil-water-holding capacity data. A dekadal rangeland WRSI has been operational for east and west Africa since 2005. User feedback has been encouraging, especially with regard to the end-of-season WRSI anomaly products that compare the index's performance to 'normal' years. Currently, rangeland WRSI products are generated on a dekadal basis and posted for free distribution on the US Geological Survey early warning website at http://earlywarning.usgs.gov/adds/.

  15. Pkd1 is Required for Male Reproductive tract Development

    PubMed Central

    Nie, Xuguang; Arend, Lois J.

    2016-01-01

    Reproductive tract abnormalities and male infertility have higher incidence in autosomal dominant polycystic kidney disease (ADPKD) patients than in general population. In this work, we revealed that Pkd1, whose mutations account for 85% of ADPKD cases, is essential for male reproductive tract development. Disruption of Pkd1 caused a spectrum of defects in the murine male reproductive tract. The earliest visible defect in Pkd1-/- reproductive tract was cystic dilation of the efferent ducts, which are derivatives of the mesonephric tubules. Epididymis development was delayed or arrested in the Pkd1-/- mice. No sign of epididymal coiling was seen in the Pkd1 null mice. Disruption of Pkd1 in epithelia alone using the Pax2-cre mice was sufficient to cause efferent duct dilation and coiling defect in the epididymis, suggesting that Pkd1 is critical for epithelial development and maintenance in male reproductive tract. In-depth analysis showed that Pkd1 is required to maintain tubulin cytoskeleton and important for Tgf-β/Bmp signal transduction in the epithelia of male reproductive tract. Altogether, our results provide the first direct evidence for developmental roles of Pkd1 in male reproductive tract and provide new insights in reproductive tract abnormalities and infertility in ADPKD patients. PMID:23933588

  16. Development of a Thrust Stand to Meet LISA Mission Requirements

    NASA Technical Reports Server (NTRS)

    Willis, William D., III; Zakrzwski, Charles M.; Merkowitz, Stephen M.

    2002-01-01

    A thrust stand has been built to measure the force-noise produced by electrostatic micro-Newton (muN) thrusters. The LISA mission's Disturbance Reduction System (DRS) requires thrusters that are capable of producing continuous thrust levels between 1-100 muN with a resolution of 0.1 muN. The stationary force-noise produced by these thrusters must not exceed 0.1 muN/dHz in the measurement bandwidth 10(exp -4) to 1 Hz. The LISA Thrust Stand (LTS) is a torsion-balance type thrust stand designed to meet the following requirements: stationary force-noise measurements from l0( -4) to 1 Hz with 0.1 muN/dHz sensitivity, absolute thrust measurements from 1-100 muN with better than 0.1 muN resolution, and dynamic thruster response from to 10 Hz. The LTS employs a unique vertical configuration, autocollimator for angular position measurements, and electrostatic actuators that are used for dynamic pendulum control and null-mode measurements. Force-noise levels are measured indirectly by characterizing the thrust stand as a spring-mass system. The LTS was initially designed to test the indium FEEP thruster developed by the Austrian Research Center in Seibersdorf (ARCS), but can be modified for testing other thrusters of this type.

  17. Software requirements specification document for the AREST code development

    SciTech Connect

    Engel, D.W.; McGrail, B.P.; Whitney, P.D.; Gray, W.J.; Williford, R.E.; White, M.D.; Eslinger, P.W.; Altenhofen, M.K.

    1993-11-01

    The Analysis of the Repository Source Term (AREST) computer code was selected in 1992 by the U.S. Department of Energy. The AREST code will be used to analyze the performance of an underground high level nuclear waste repository. The AREST code is being modified by the Pacific Northwest Laboratory (PNL) in order to evaluate the engineered barrier and waste package designs, model regulatory compliance, analyze sensitivities, and support total systems performance assessment modeling. The current version of the AREST code was developed to be a very useful tool for analyzing model uncertainties and sensitivities to input parameters. The code has also been used successfully in supplying source-terms that were used in a total systems performance assessment. The current version, however, has been found to be inadequate for the comparison and selection of a design for the waste package. This is due to the assumptions and simplifications made in the selection of the process and system models. Thus, the new version of the AREST code will be designed to focus on the details of the individual processes and implementation of more realistic models. This document describes the requirements of the new models that will be implemented. Included in this document is a section describing the near-field environmental conditions for this waste package modeling, description of the new process models that will be implemented, and a description of the computer requirements for the new version of the AREST code.

  18. Development of A Thrust Stand to Meet LISA Mission Requirements

    NASA Technical Reports Server (NTRS)

    Willis, William D., III; Zakrzwski, C. M.; Bauer, Frank H. (Technical Monitor)

    2002-01-01

    A thrust stand has been built and tested that is capable of measuring the force-noise produced by electrostatic micro-Newton (micro-Newton) thrusters. The LISA mission's Disturbance Reduction System (DRS) requires thrusters that are capable of producing continuous thrust levels between 1-100 micro-Newton with a resolution of 0.1 micro-Newton. The stationary force-noise produced by these thrusters must not exceed 0.1 pN/4Hz in a 10 Hz bandwidth. The LISA Thrust Stand (LTS) is a torsion-balance type thrust stand designed to meet the following requirements: stationary force-noise measurements from 10(exp-4) to 1 Hz with 0.1 micro-Newton resolution, absolute thrust measurements from 1-100 micro-Newton with better than 0.1 micro-Newton resolution, and dynamic thruster response from 10(exp -4) to 10 Hz. The ITS employs a unique vertical configuration, autocollimator for angular position measurements, and electrostatic actuators that are used for dynamic pendulum control and null-mode measurements. Force-noise levels are measured indirectly by characterizing the thrust stand as a spring-mass system. The LTS was initially designed to test the indium FEEP thruster developed by the Austrian Research Center in Seibersdorf (ARCS), but can be modified for testing other thrusters of this type.

  19. Developing operational safety requirements for non-nuclear facilities

    SciTech Connect

    Mahn, J.A.

    1997-11-01

    Little guidance has been provided by the DOE for developing appropriate Operational Safety Requirements (OSR) for non-nuclear facility safety documents. For a period of time, Chapter 2 of DOE/AL Supplemental Order 5481.lB provided format guidance for non-reactor nuclear facility OSRs when this supplemental order applied to both nuclear and non-nuclear facilities. Thus, DOE Albuquerque Operations Office personnel still want to see non-nuclear facility OSRs in accordance with the supplemental order (i.e., in terms of Safety Limits, Limiting Conditions for Operation, and Administrative Controls). Furthermore, they want to see a clear correlation between the OSRs and the results of a facility safety analysis. This paper demonstrates how OSRs can be rather simply derived from the results of a risk assessment performed using the ``binning`` methodology of SAND95-0320.

  20. MSC p43 required for axonal development in motor neurons

    PubMed Central

    Zhu, Xiaodong; Liu, Yang; Yin, Yanqing; Shao, Aiyun; Zhang, Bo; Kim, Sunghoon; Zhou, Jiawei

    2009-01-01

    Neuron connectivity and correct neural function largely depend on axonal integrity. Neurofilaments (NFs) constitute the main cytoskeletal network maintaining the structural integrity of neurons and exhibit dynamic changes during axonal and dendritic growth. However, the mechanisms underlying axonal development and maintenance remain poorly understood. Here, we identify that multisynthetase complex p43 (MSC p43) is essential for NF assembly and axon maintenance. The MSC p43 protein was predominantly expressed in central neurons and interacted with NF light subunit in vivo. Mice lacking MSC p43 exhibited axon degeneration in motor neurons, defective neuromuscular junctions, muscular atrophy, and motor dysfunction. Furthermore, MSC p43 depletion in mice caused disorganization of the axonal NF network. Mechanistically, MSC p43 is required for maintaining normal phosphorylation levels of NFs. Thus, MSC p43 is indispensable in maintaining axonal integrity. Its dysfunction may underlie the NF disorganization and axon degeneration associated with motor neuron degenerative diseases. PMID:19717447

  1. International Agreement on Planetary Protection

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The maintenance of a NASA policy, is consistent with international agreements. The planetary protection policy management in OSS, with Field Center support. The advice from internal and external advisory groups (NRC, NAC/Planetary Protection Task Force). The technology research and standards development in bioload characterization. The technology research and development in bioload reduction/sterilization. This presentation focuses on: forward contamination - research on the potential for Earth life to exist on other bodies, improved strategies for planetary navigation and collision avoidance, and improved procedures for sterile spacecraft assembly, cleaning and/or sterilization; and backward contamination - development of sample transfer and container sealing technologies for Earth return, improvement in sample return landing target assessment and navigation strategy, planning for sample hazard determination requirements and procedures, safety certification, (liaison to NEO Program Office for compositional data on small bodies), facility planning for sample recovery system, quarantine, and long-term curation of 4 returned samples.

  2. Ferritin Is Required in Multiple Tissues during Drosophila melanogaster Development

    PubMed Central

    Blowes, Liisa M.; Missirlis, Fanis; Riesgo-Escovar, Juan R.

    2015-01-01

    In Drosophila melanogaster, iron is stored in the cellular endomembrane system inside a protein cage formed by 24 ferritin subunits of two types (Fer1HCH and Fer2LCH) in a 1:1 stoichiometry. In larvae, ferritin accumulates in the midgut, hemolymph, garland, pericardial cells and in the nervous system. Here we present analyses of embryonic phenotypes for mutations in Fer1HCH, Fer2LCH and in both genes simultaneously. Mutations in either gene or deletion of both genes results in a similar set of cuticular embryonic phenotypes, ranging from non-deposition of cuticle to defects associated with germ band retraction, dorsal closure and head involution. A fraction of ferritin mutants have embryonic nervous systems with ventral nerve cord disruptions, misguided axonal projections and brain malformations. Ferritin mutants die with ectopic apoptotic events. Furthermore, we show that ferritin maternal contribution, which varies reflecting the mother’s iron stores, is used in early development. We also evaluated phenotypes arising from the blockage of COPII transport from the endoplasmic reticulum to the Golgi apparatus, feeding the secretory pathway, plus analysis of ectopically expressed and fluorescently marked Fer1HCH and Fer2LCH. Overall, our results are consistent with insect ferritin combining three functions: iron storage, intercellular iron transport, and protection from iron-induced oxidative stress. These functions are required in multiple tissues during Drosophila embryonic development. PMID:26192321

  3. Histone Deacetylase 3 Is Required for Efficient T Cell Development

    PubMed Central

    Stengel, Kristy R.; Zhao, Yue; Klus, Nicholas J.; Kaiser, Jonathan F.; Gordy, Laura E.; Joyce, Sebastian

    2015-01-01

    Hdac3 is a key target for Hdac inhibitors that are efficacious in cutaneous T cell lymphoma. Moreover, the regulation of chromatin structure is critical as thymocytes transition from an immature cell with open chromatin to a mature T cell with tightly condensed chromatin. To define the phenotypes controlled by Hdac3 during T cell development, we conditionally deleted Hdac3 using the Lck-Cre transgene. This strategy inactivated Hdac3 in the double-negative stages of thymocyte development and caused a significant impairment at the CD8 immature single-positive (ISP) stage and the CD4/CD8 double-positive stage, with few mature CD4+ or CD8+ single-positive cells being produced. When Hdac3−/− mice were crossed with Bcl-xL-, Bcl2-, or TCRβ-expressing transgenic mice, a modest level of complementation was found. However, when the null mice were crossed with mice expressing a fully rearranged T cell receptor αβ transgene, normal levels of CD4 single-positive cells were produced. Thus, Hdac3 is required for the efficient transit from double-negative stage 4 through positive selection. PMID:26324326

  4. Histone Deacetylase 3 Is Required for Efficient T Cell Development.

    PubMed

    Stengel, Kristy R; Zhao, Yue; Klus, Nicholas J; Kaiser, Jonathan F; Gordy, Laura E; Joyce, Sebastian; Hiebert, Scott W; Summers, Alyssa R

    2015-11-01

    Hdac3 is a key target for Hdac inhibitors that are efficacious in cutaneous T cell lymphoma. Moreover, the regulation of chromatin structure is critical as thymocytes transition from an immature cell with open chromatin to a mature T cell with tightly condensed chromatin. To define the phenotypes controlled by Hdac3 during T cell development, we conditionally deleted Hdac3 using the Lck-Cre transgene. This strategy inactivated Hdac3 in the double-negative stages of thymocyte development and caused a significant impairment at the CD8 immature single-positive (ISP) stage and the CD4/CD8 double-positive stage, with few mature CD4(+) or CD8(+) single-positive cells being produced. When Hdac3(-/-) mice were crossed with Bcl-xL-, Bcl2-, or TCRβ-expressing transgenic mice, a modest level of complementation was found. However, when the null mice were crossed with mice expressing a fully rearranged T cell receptor αβ transgene, normal levels of CD4 single-positive cells were produced. Thus, Hdac3 is required for the efficient transit from double-negative stage 4 through positive selection. PMID:26324326

  5. Developing Metadata Requirements for NASA Airborne Field Campaigns

    NASA Astrophysics Data System (ADS)

    Parker, L.; Rinsland, P. L.; Kusterer, J.; Chen, G.; Early, A. B.; Beach, A. L., III; Wang, D.; Typanski, N. D.; Rutherford, M.; Rieflin, E.

    2014-12-01

    The common definition of metadata is "data about data". NASA has developed metadata formats to meet the needs of its satellite missions and emerging users. Coverage of satellite missions is highly predictable based on orbit characteristics. Airborne missions feature complicated flight patterns to maximize science return and changes in the instrument suites. More relevant to the airborne science data holding, the metadata describes the airborne measurements, in terms of measurement location, time, platform, and instruments. The metadata organizes the data holdings and facilitates the data ordering process from the DAAC. Therefore, the metadata requirements will need to fit the type of airborne measurements and sampling strategies as well as leverage current Earth Science and Data Information System infrastructure (ECHO/Reverb, GCMD). Current airborne data is generated/produced in a variety of formats (ICARRT, ASCII, etc) with the metadata information embedded in the data file. Special readers are needed to parse data file to generate metadata needed for search and discovery. With loosely defined standards within the airborne community this process poses challenges to the data providers. It is necessary to assess the suitability of current metadata standards, which have been mostly developed for satellite observations. To be presented are the use case-based assessments of the current airborne metadata standards and suggestions for future changes.

  6. Countries renew rescue agreement

    NASA Astrophysics Data System (ADS)

    Bush, Susan M.

    To insure long-term continuity for the international satellite search and rescue system, COSPAS/SARSAT, an intergovernmental agreement binding the four sponsoring nations to cooperate was signed July 1 in Paris. According to Russell Vollmers of the National Oceanic and Atmospheric Administration, the agreement is binding for 15 years, with an automatic extension.The system marked the fifth anniversary of its first rescue last year, when on September 10, 1982, three persons were rescued. Begun in the 1970s by NASA as an experiment, COSPAS/SARSAT (a Russian-English acronym) is now a cooperative project among the United States, Canada, France, and the Soviet Union. Its goal is to reduce the time required to rescue air and maritime distress victims and also to locate victims who otherwise may not be found, thus using the satellite system as a life-saving device.

  7. 48 CFR 16.702 - Basic agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    .... Basic agreements may need to be revised before the annual review due to mandatory statutory requirements... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Basic agreements. 16.702... AND CONTRACT TYPES TYPES OF CONTRACTS Agreements 16.702 Basic agreements. (a) Description. A...

  8. Proline is required for male gametophyte development in Arabidopsis

    PubMed Central

    2012-01-01

    . Conclusions Our data show that the development of the male gametophyte carrying mutations in both P5CS1 and P5CS2 is severely compromised, and indicate that proline is required for pollen development and transmission. PMID:23234543

  9. A new market risk model for cogeneration project financing---combined heat and power development without a power purchase agreement

    NASA Astrophysics Data System (ADS)

    Lockwood, Timothy A.

    Federal legislative changes in 2006 no longer entitle cogeneration project financings by law to receive the benefit of a power purchase agreement underwritten by an investment-grade investor-owned utility. Consequently, this research explored the need for a new market-risk model for future cogeneration and combined heat and power (CHP) project financing. CHP project investment represents a potentially enormous energy efficiency benefit through its application by reducing fossil fuel use up to 55% when compared to traditional energy generation, and concurrently eliminates constituent air emissions up to 50%, including global warming gases. As a supplemental approach to a comprehensive technical analysis, a quantitative multivariate modeling was also used to test the statistical validity and reliability of host facility energy demand and CHP supply ratios in predicting the economic performance of CHP project financing. The resulting analytical models, although not statistically reliable at this time, suggest a radically simplified CHP design method for future profitable CHP investments using four easily attainable energy ratios. This design method shows that financially successful CHP adoption occurs when the average system heat-to-power-ratio supply is less than or equal to the average host-convertible-energy-ratio, and when the average nominally-rated capacity is less than average host facility-load-factor demands. New CHP investments can play a role in solving the world-wide problem of accommodating growing energy demand while preserving our precious and irreplaceable air quality for future generations.

  10. Spacelab user implementation assessment study. Volume 3: Resource requirements development

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The resources requirements for the integration and checkout of spacelab payloads are presented in three categories: mission-unique, sustaining, and non-recurring. The requirements are identified by concept and by center. Cost estimates for the resource requirements are also presented.

  11. The Development of Project Orion Ground Safety Requirements

    NASA Technical Reports Server (NTRS)

    Kirkpatrick, Paul; Condzella, Bill; Williams, Jeff

    2011-01-01

    In spite of a very compressed schedule, Project Orion's AFT safety team was able to pull together a comprehensive set of ground safety requirements using existing requirements and subject matter experts. These requirements will serve as the basis for the design of GSE and ground operations. Using the above lessons as a roadmap, new Projects can produce the same results. A rigorous set of ground safety requirements is required to assure ground support equipment (GSE) and associated flight hardware ground operations are conducted safety

  12. Thermal requirements and development of Herpetogramma phaeopteralis (Lepidoptera: Crambidae: Spilomelinae).

    PubMed

    Tofangsazi, Nastaran; Buss, Eileen A; Meagher, Robert; Mascarin, Gabriel M; Arthurs, Steven P

    2012-10-01

    ABSTRACT The tropical sod webworm, Herpetogramma phaeopteralis Guenée is a major turfgrass pest in the southeastern United States. We evaluated larval development on five artificial diets and at six temperatures (15, 20, 25, 30, 32.5, 35 +/- 1 degree C) on St. Augustinegrass (Stenotaphrum secundatum (Walter) Kuntze). Only larvae fed St. Augustinegrass and soy-wheat germ diets completed their lifecycles. None of the artificial diets tested (corn-based, soy-wheat germ, corn cob-wheat germ, corn cob-soy flour, or pinto bean) were suitable for rearing this species, because of high mortality and slower developmental time. Total developmental time (oviposition to adult) on S. secundatum significantly decreased from 47.8 d at 20 degrees C to 21.1 d at 30 degrees C, and then increased to 32.6 d at 32.5 degrees C. Tropical sod webworm failed to complete larval development at 15 and 35 degrees C. The relationship between temperature and developmental rate was described using linear (common and polynomial) and nonlinear models (Briere-1, Briere-2, and Lactin-2). The estimated lower temperature thresholds using a linear model for eggs, first, second, third, fourth, fifth, and sixth instars, prepupa, pupa, and total development were 10.1, 6.9, 12.3, 10.5, 15.3, 13.9, 9.1, 13.1, 12.0, and 13.1 degrees C, and the thermal constant of these stages were 62.9, 66.2, 38.2, 40.3, 24.9, 32.3, 51.9, 106.4, 109.9, and 370.4 degree-days, respectively. The Briere-1 model provided the best fit with estimated lower, upper, and optimum thresholds for total development of 14.9, 34.3, and 29.4 degrees C, respectively. The developmental requirements of H. phaeopteralis can be used to help predict the distribution and seasonal phenology of this pest. PMID:23156152

  13. Deciphering animal development through proteomics: requirements and prospects

    PubMed Central

    Reintsch, Wolfgang E; Mandato, Craig A

    2008-01-01

    In recent years proteomic techniques have started to become very useful tools in a variety of model systems of developmental biology. Applications cover many different aspects of development, including the characterization of changes in the proteome during early embryonic stages. During early animal development the embryo becomes patterned through the temporally and spatially controlled activation of distinct sets of genes. Patterning information is then translated, from gastrulation onwards, into regional specific morphogenetic cell and tissue movements that give the embryo its characteristic shape. On the molecular level, patterning is the outcome of intercellular communication via signaling molecules and the local activation or repression of transcription factors. Genetic approaches have been used very successfully to elucidate the processes behind these events. Morphogenetic movements, on the other hand, have to be orchestrated through regional changes in the mechanical properties of cells. The molecular mechanisms that govern these changes have remained much more elusive, at least in part due to the fact that they are more under translational/posttranslational control than patterning events. However, recent studies indicate that proteomic approaches can provide the means to finally unravel the mechanisms that link patterning to the generation of embryonic form. To intensify research in this direction will require close collaboration between proteome scientists and developmental researchers. It is with this aim in mind that we first give an outline of the classical questions of patterning and morphogenesis. We then summarize the proteomic approaches that have been applied in developmental model systems and describe the pioneering studies that have been done to study morphogenesis. Finally we discuss current and future strategies that will allow characterizing the changes in the embryonic proteome and ultimately lead to a deeper understanding of the cellular

  14. Chronic itch development in sensory neurons requires BRAF signaling pathways

    PubMed Central

    Zhao, Zhong-Qiu; Huo, Fu-Quan; Jeffry, Joseph; Hampton, Lori; Demehri, Shadmehr; Kim, Seungil; Liu, Xian-Yu; Barry, Devin M.; Wan, Li; Liu, Zhong-Chun; Li, Hui; Turkoz, Ahu; Ma, Kaijie; Cornelius, Lynn A.; Kopan, Raphael; Battey, James F.; Zhong, Jian; Chen, Zhou-Feng

    2013-01-01

    Chronic itch, or pruritus, is associated with a wide range of skin abnormalities. The mechanisms responsible for chronic itch induction and persistence remain unclear. We developed a mouse model in which a constitutively active form of the serine/threonine kinase BRAF was expressed in neurons gated by the sodium channel Nav1.8 (BRAFNav1.8 mice). We found that constitutive BRAF pathway activation in BRAFNav1.8 mice results in ectopic and enhanced expression of a cohort of itch-sensing genes, including gastrin-releasing peptide (GRP) and MAS-related GPCR member A3 (MRGPRA3), in nociceptors expressing transient receptor potential vanilloid 1 (TRPV1). BRAFNav1.8 mice showed de novo neuronal responsiveness to pruritogens, enhanced pruriceptor excitability, and heightened evoked and spontaneous scratching behavior. GRP receptor expression was increased in the spinal cord, indicating augmented coding capacity for itch subsequent to amplified pruriceptive inputs. Enhanced GRP expression and sustained ERK phosphorylation were observed in sensory neurons of mice with allergic contact dermatitis– or dry skin–elicited itch; however, spinal ERK activation was not required for maintaining central sensitization of itch. Inhibition of either BRAF or GRP signaling attenuated itch sensation in chronic itch mouse models. These data uncover RAF/MEK/ERK signaling as a key regulator that confers a subset of nociceptors with pruriceptive properties to initiate and maintain long-lasting itch sensation. PMID:24216512

  15. Innovative Approach for Developing Spacecraft Interior Acoustic Requirement Allocation

    NASA Technical Reports Server (NTRS)

    Chu, S. Reynold; Dandaroy, Indranil; Allen, Christopher S.

    2016-01-01

    The Orion Multi-Purpose Crew Vehicle (MPCV) is an American spacecraft for carrying four astronauts during deep space missions. This paper describes an innovative application of Power Injection Method (PIM) for allocating Orion cabin continuous noise Sound Pressure Level (SPL) limits to the sound power level (PWL) limits of major noise sources in the Environmental Control and Life Support System (ECLSS) during all mission phases. PIM is simulated using both Statistical Energy Analysis (SEA) and Hybrid Statistical Energy Analysis-Finite Element (SEA-FE) models of the Orion MPCV to obtain the transfer matrix from the PWL of the noise sources to the acoustic energies of the receivers, i.e., the cavities associated with the cabin habitable volume. The goal of the allocation strategy is to control the total energy of cabin habitable volume for maintaining the required SPL limits. Simulations are used to demonstrate that applying the allocated PWLs to the noise sources in the models indeed reproduces the SPL limits in the habitable volume. The effects of Noise Control Treatment (NCT) on allocated noise source PWLs are investigated. The measurement of source PWLs of involved fan and pump development units are also discussed as it is related to some case-specific details of the allocation strategy discussed here.

  16. spib is required for primitive myeloid development in Xenopus.

    PubMed

    Costa, Ricardo M B; Soto, Ximena; Chen, Yaoyao; Zorn, Aaron M; Amaya, Enrique

    2008-09-15

    Vertebrate blood formation occurs in 2 spatially and temporally distinct waves, so-called primitive and definitive hematopoiesis. Although definitive hematopoiesis has been extensively studied, the development of primitive myeloid blood has received far less attention. In Xenopus, primitive myeloid cells originate in the anterior ventral blood islands, the equivalent of the mammalian yolk sac, and migrate out to colonize the embryo. Using fluorescence time-lapse video microscopy, we recorded the migratory behavior of primitive myeloid cells from their birth. We show that these cells are the first blood cells to differentiate in the embryo and that they are efficiently recruited to embryonic wounds, well before the establishment of a functional vasculature. Furthermore, we isolated spib, an ETS transcription factor, specifically expressed in primitive myeloid precursors. Using spib antisense morpholino knockdown experiments, we show that spib is required for myeloid specification, and, in its absence, primitive myeloid cells retain hemangioblast-like characteristics and fail to migrate. Thus, we conclude that spib sits at the top of the known genetic hierarchy that leads to the specification of primitive myeloid cells in amphibians. PMID:18594023

  17. Developing Formal Correctness Properties from Natural Language Requirements

    NASA Technical Reports Server (NTRS)

    Nikora, Allen P.

    2006-01-01

    This viewgraph presentation reviews the rationale of the program to transform natural language specifications into formal notation.Specifically, automate generation of Linear Temporal Logic (LTL)correctness properties from natural language temporal specifications. There are several reasons for this approach (1) Model-based techniques becoming more widely accepted, (2) Analytical verification techniques (e.g., model checking, theorem proving) significantly more effective at detecting types of specification design errors (e.g., race conditions, deadlock) than manual inspection, (3) Many requirements still written in natural language, which results in a high learning curve for specification languages, associated tools and increased schedule and budget pressure on projects reduce training opportunities for engineers, and (4) Formulation of correctness properties for system models can be a difficult problem. This has relevance to NASA in that it would simplify development of formal correctness properties, lead to more widespread use of model-based specification, design techniques, assist in earlier identification of defects and reduce residual defect content for space mission software systems. The presentation also discusses: potential applications, accomplishments and/or technological transfer potential and the next steps.

  18. Child Development Functionality Assessment Guide: Standards and Requirements for Developing Most Efficient Organizations.

    ERIC Educational Resources Information Center

    Department of the Army, Washington, DC.

    As part of its cost containment efforts, the U.S. Navy continues to evaluate its child development program to expand availability without compromising the high quality standards required by the 1989 Military Child Care Act. This manual provides guidelines for conducting Functionality Assessments (FA) and delineates the standards and requirements…

  19. 48 CFR 1542.1203 - Processing agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MANAGEMENT CONTRACT ADMINISTRATION Novation and Change of Name Agreements 1542.1203 Processing agreements. (a... required documentary evidence. (2) Verify the accuracy of the list of contracts through the...

  20. 76 FR 61704 - Notice of Agreements Filed

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ... requirement. Agreement No.: 012136. Title: HSDG/ML/MSC Space Charter Agreement. Parties: Hamburg-Sud, A.P... authorizes Hamburg-Sud and Maersk to charter space to Med Shipping in the trade between U.S. Atlantic...

  1. The Development of Suppletive and Affixal Tense and Agreement Morphemes in the L3 English of Basque-Spanish Bilinguals

    ERIC Educational Resources Information Center

    Garcia Mayo, Maria del Pilar; Villarreal Olaizola, Izaskun

    2011-01-01

    This article examines the third language (L3) developing morphology of 78 Basque-Spanish bilinguals following a Content and Language Integrated Learning (CLIL) program and a mainstream English as a foreign language (non-CLIL) program. The analysis of cross-sectional and longitudinal oral data shows that (1) the omission of inflection in the L3…

  2. 28 CFR 56.2 - Maintenance of records with respect to meetings held to develop voluntary agreements or plans of...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... to the Department of Energy. The Department of Energy may, upon written notice to potential... International Energy Program. 56.2 Section 56.2 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) INTERNATIONAL ENERGY PROGRAM § 56.2 Maintenance of records with respect to meetings held to develop...

  3. 28 CFR 56.2 - Maintenance of records with respect to meetings held to develop voluntary agreements or plans of...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... to the Department of Energy. The Department of Energy may, upon written notice to potential... International Energy Program. 56.2 Section 56.2 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) INTERNATIONAL ENERGY PROGRAM § 56.2 Maintenance of records with respect to meetings held to develop...

  4. 28 CFR 56.2 - Maintenance of records with respect to meetings held to develop voluntary agreements or plans of...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... to the Department of Energy. The Department of Energy may, upon written notice to potential... International Energy Program. 56.2 Section 56.2 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) INTERNATIONAL ENERGY PROGRAM § 56.2 Maintenance of records with respect to meetings held to develop...

  5. Oligopeptidase A is required for normal phage P22 development.

    PubMed Central

    Conlin, C A; Vimr, E R; Miller, C G

    1992-01-01

    The opdA gene of Salmonella typhimurium encodes an endoprotease, oligopeptidase A (OpdA). Strains carrying opdA mutations were deficient as hosts for phage P22. P22 and the closely related phages L and A3 formed tiny plaques on an opdA host. Salmonella phages 9NA, KB1, and ES18.h1 were not affected by opdA mutations. Although opdA strains displayed normal doubling times and were infected by P22 as efficiently as opdA+ strains, the burst size of infectious particles from an opdA host was less than 1/10 of that from an opdA+ host. This decrease resulted from a reduced efficiency of plating of particles from an opdA infection. In the absence of a functional opdA gene, most of the P22 particles are defective. To identify the target of OpdA action, P22 mutants which formed plaques larger than wild-type plaques on an opdA mutant lawn were isolated. Marker rescue experiments using cloned fragments of P22 DNA localized these mutations to a 1-kb fragment. The nucleotide sequence of this fragment and a contiguous region (including all of both P22 gene 7 and gene 14) was determined. The mutations leading to opdA independence affected the region of gene 7 coding for the amino terminus of gp7, a protein required for DNA injection by the phage. Comparison of the nucleotide sequence with the N-terminal amino acid sequence of gp7 suggested that a 20-amino-acid peptide is removed from gp7 during phage development. Further experiments showed that this processing was opdA dependent and rapid (half-life, less than 2 min) and occurred in the absence of other phage proteins. The opdA-independent mutations lead to mutant forms of gp7 which function without processing. Images PMID:1522065

  6. Agreement among 2 x 2 Agreement Indices.

    ERIC Educational Resources Information Center

    Conger, Anthony J.; Ward, David G.

    1984-01-01

    Sixteen measures of reliability for two-category nominal scales are compared. Upon correcting for chance agreement, there are only five distinct indices: Fleiss's modification of A-sub-1, the phi coefficient, Cohen's kappa, and two intraclass coefficients. Recommendations for choosing an agreement index are made based on definitions, magnitude,…

  7. U.S. Geological Survey and Microsoft Cooperative Research and Development Agreement: Geospatial Data Browsing and Retrieval Site on the World Wide Web

    USGS Publications Warehouse

    U.S. Geological Survey

    1998-01-01

    In May 1997, the U.S. Geological Survey (USGS) and the Microsoft Corporation of Redmond, Wash., entered into a cooperative research and development agreement (CRADA) to make vast amounts of geospatial data available to the general public through the Internet. The CRADA is a 36-month joint effort to develop a general, public-oriented browsing and retrieval site for geospatial data on the Internet. Specifically, Microsoft plans to (1) modify a large volume of USGS geospatial data so the images can be displayed quickly and easily over the Internet, (2) implement an easy-to-use interface for low-speed connections, and (3) develop an Internet Web site capable of servicing millions of users per day.

  8. U.S. Geological Survey and Microsoft Cooperative Research and Development Agreement: Geospatial Data Browsing and Retrieval Site on the World Wide Web

    USGS Publications Warehouse

    U.S. Geological Survey

    1999-01-01

    In May 1997, the U.S. Geological Survey (USGS) and the Microsoft Corporation of Redmond, Wash., entered into a cooperative research and development agreement (CRADA) to make vast amounts of geospatial data available to the general public through the Internet. The CRADA is a 36-month joint effort to develop a general, public-oriented browsing and retrieval site for geospatial data on the Internet. Specifically, Microsoft plans to (1) modify a large volume of USGS geospatial data so the images can be displayed quickly and easily over the Internet, (2) implement an easy-to-use interface for low-speed connections, and (3) develop an Internet Web site capable of servicing millions of users per day.

  9. 2 CFR 182.620 - Cooperative agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... agreement. Cooperative agreement means an award of financial assistance that, consistent with 31 U.S.C. 6305... development agreements as defined in 15 U.S.C. 3710a. ... MANAGEMENT AND BUDGET GOVERNMENTWIDE GUIDANCE FOR GRANTS AND AGREEMENTS NATIONAL POLICY...

  10. Exploration Requirements Development Utilizing the Strategy-to-Task-to-Technology Development Approach

    NASA Technical Reports Server (NTRS)

    Drake, Bret G.; Josten, B. Kent; Monell, Donald W.

    2004-01-01

    The Vision for Space Exploration provides direction for the National Aeronautics and Space Administration to embark on a robust space exploration program that will advance the Nation s scientific, security, and economic interests. This plan calls for a progressive expansion of human capabilities beyond low earth orbit seeking to answer profound scientific and philosophical questions while responding to discoveries along the way. In addition, the Vision articulates the strategy for developing the revolutionary new technologies and capabilities required for the future exploration of the solar system. The National Aeronautics and Space Administration faces new challenges in successfully implementing the Vision. In order to implement a sustained and affordable exploration endeavor it is vital for NASA to do business differently. This paper provides an overview of the strategy-to-task-to-technology process being used by NASA s Exploration Systems Mission Directorate to develop the requirements and system acquisition details necessary for implementing a sustainable exploration vision.

  11. Development and Modification of a Required Family Medicine Clerkship.

    ERIC Educational Resources Information Center

    Michener, J. Lloyd; And Others

    1985-01-01

    A new required clinical clerkship in family medicine at Duke University School of Medicine is described in terms of planning, implementation, and modification in response to students' evaluations. The data demonstrate that family medicine can be taught effectively as a core clinical rotation. (Author/MLW)

  12. Student Performance Requirements: Minitary Service. Continuation Education System Development Project.

    ERIC Educational Resources Information Center

    La Puente Union High School District, CA.

    Funded under Title III of the Elementary and Secondary Education Act of 1965, the La Puente, California, continuation education project investigated (1) attitudes of former students concerning the success of the school in preparing them for entry into military service, (2) the minimal skills and knowledge required by each of the armed forces, (3)…

  13. 14 CFR 152.111 - Application requirements: Airport development.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Transportation (49 CFR 25.57 and 25.59), whether or not reimbursement is being requested for the costs of... Act (40 CFR part 15). (7) The assurances on Civil Rights required by § 21.7 of the Regulations of the Office of the Secretary of Transportation (49 CFR 21.7) and § 152.405. (8) Plans and specifications...

  14. 14 CFR 152.111 - Application requirements: Airport development.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Transportation (49 CFR 25.57 and 25.59), whether or not reimbursement is being requested for the costs of... Act (40 CFR part 15). (7) The assurances on Civil Rights required by § 21.7 of the Regulations of the Office of the Secretary of Transportation (49 CFR 21.7) and § 152.405. (8) Plans and specifications...

  15. 10 CFR 607.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Cooperative agreement. 607.620 Section 607.620 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 607.620 Cooperative agreement. Cooperative agreement means an award...

  16. 45 CFR 630.620 - Cooperative agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Cooperative agreement. 630.620 Section 630.620 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 630.620 Cooperative agreement. Cooperative agreement means an award...

  17. 20 CFR 439.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Cooperative agreement. 439.620 Section 439.620 Employees' Benefits SOCIAL SECURITY ADMINISTRATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 439.620 Cooperative agreement. Cooperative agreement means...

  18. 46 CFR 390.5 - Agreement vessels.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Agreement vessels. 390.5 Section 390.5 Shipping MARITIME....5 Agreement vessels. (a) In general. 46 U.S.C. 53501 states the requirements for eligible, qualified and agreement vessels. The rules in this section further define such terms and state how vessels...

  19. 46 CFR 390.5 - Agreement vessels.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false Agreement vessels. 390.5 Section 390.5 Shipping MARITIME....5 Agreement vessels. (a) In general. 46 U.S.C. 53501 states the requirements for eligible, qualified and agreement vessels. The rules in this section further define such terms and state how vessels...

  20. 46 CFR 390.5 - Agreement vessels.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false Agreement vessels. 390.5 Section 390.5 Shipping MARITIME....5 Agreement vessels. (a) In general. 46 U.S.C. 53501 states the requirements for eligible, qualified and agreement vessels. The rules in this section further define such terms and state how vessels...

  1. 46 CFR 390.5 - Agreement vessels.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 8 2012-10-01 2012-10-01 false Agreement vessels. 390.5 Section 390.5 Shipping MARITIME....5 Agreement vessels. (a) In general. 46 U.S.C. 53501 states the requirements for eligible, qualified and agreement vessels. The rules in this section further define such terms and state how vessels...

  2. Requirements to the procedure and stages of innovative fuel development

    NASA Astrophysics Data System (ADS)

    Troyanov, V.; Zabudko, L.; Grachyov, A.; Zhdanova, O.

    2016-04-01

    According to the accepted current understanding under the nuclear fuel we will consider the assembled active zone unit (Fuel assembly) with its structural elements, fuel rods, pellet column, structural materials of fuel rods and fuel assemblies. The licensing process includes justification of safe application of the proposed modifications, including design-basis and experimental justification of the modified items under normal operating conditions and in violation of normal conditions, including accidents as well. Besides the justification of modified units itself, it is required to show the influence of modifications on the performance and safety of the other Reactor Unit’ and Nuclear Plant’ elements (e.g. burst can detection system, transportation and processing operations during fuel handling), as well as to justify the new standards of fuel storage etc. Finally, the modified fuel should comply with the applicable regulations, which often becomes a very difficult task, if only because those regulations, such as the NP-082-07, are not covered modification issues. Making amendments into regulations can be considered as the only solution, but the process is complicated and requires deep grounds for amendments. Some aspects of licensing new nuclear fuel are considered the example of mixed nitride uranium -plutonium fuel application for the BREST reactor unit.

  3. The oil and gas joint operating agreement

    SciTech Connect

    Not Available

    1990-01-01

    This book covers the following topics: introduction to the AAPL model form operating agreement; property provisions of the operating agreement; Article 6---the drilling and development article; duties and obligations revisited---who bear what risk of loss; operator's liens; accounting procedure joint operations; insurance; taking gas in kind absent a balancing agreement; RMMLF Form 5 Gas Balancing Agreement; tax partnerships for nontax professionals; alternative agreement forms.

  4. Geothermal power development in Hawaii. Volume II. Infrastructure and community-services requirements, Island of Hawaii

    SciTech Connect

    Chapman, G.A.; Buevens, W.R.

    1982-06-01

    The requirements of infrastructure and community services necessary to accommodate the development of geothermal energy on the Island of Hawaii for electricity production are identified. The following aspects are covered: Puna District-1981, labor resources, geothermal development scenarios, geothermal land use, the impact of geothermal development on Puna, labor resource requirments, and the requirements for government activity.

  5. Requirement of proline synthesis during Arabidopsis reproductive development

    PubMed Central

    2012-01-01

    Background Gamete and embryo development are crucial for successful reproduction and seed set in plants, which is often the determining factor for crop yield. Proline accumulation was largely viewed as a specific reaction to overcome stress conditions, while recent studies suggested important functions of proline metabolism also in reproductive development. Both the level of free proline and proline metabolism were proposed to influence the transition to flowering, as well as pollen and embryo development. Results In this study, we performed a detailed analysis of the contribution of individual proline biosynthetic enzymes to vegetative development and reproductive success in Arabidopsis. In contrast to previous reports, we found that pyrroline-5-carboxylate (P5C) synthetase 2 (P5CS2) is not essential for sexual reproduction although p5cs2 mutant plants were retarded in vegetative development and displayed reduced fertility under long-day conditions. Single mutant plants devoid of P5CS1 did not show any developmental defects. Simultaneous absence of both P5CS isoforms resulted in pollen sterility, while fertile egg cells could still be produced. Expression of P5C reductase (P5CR) was indispensable for embryo development but surprisingly not needed for pollen or egg cell fertility. The latter observation could be explained by an extreme stability of P5CR activity, which had a half-life time of greater than 3 weeks in vitro. Expression of P5CR-GFP under the control of the endogenous P5CR promoter was able to restore growth of homozygous p5cr mutant embryos. The analysis of P5CR-GFP-fluorescence in planta supported an exclusively cytoplasmatic localisation of P5CR. Conclusions Our results demonstrate that potential alternative pathways for proline synthesis or inter-generation transfer of proline are not sufficient to overcome a defect in proline biosynthesis from glutamate during pollen development. Proline biosynthesis through P5CS2 and P5CR is limiting for

  6. HIV testing in developing countries: what is required?

    PubMed

    Alemnji, George; Nkengasong, John N; Parekh, Bharat S

    2011-12-01

    HIV diagnostic and follow up testing are usually done in laboratory settings. However, in developing countries there is a need to decentralize testing as the majority of the population lives in rural settings. In developing countries stringent quality assurance (QA) practices, which include appropriate training, development of standard operating procedures, maintenance of operator proficiency, routine use of quality control (QC) specimens, standardized data management, equipment calibration and maintenance, and biohazard safety with proper disinfection/disposal procedures are not routinely followed to ensure reliability of results and a safe work environment. The introduction of point-of-care testing technologies involving the use of non-laboratorians in routine testing has further increased the complexity of QA. Therefore, a careful approach towards improvement of laboratories that encourages best practices, coupled with incentives, and review of government policies in point-of-care testing is needed to improve quality of testing as decentralization takes place. Development of a functional laboratory tiered network that facilitates communication, referral, training and problem solving could further enhance confidence in laboratory testing. There is also a need for special considerations in implementing a step-wise approach towards quality improvement, strengthening of the supply chain management, human capacity development, infrastructure upgrade, and strong public private partnerships to ensure long term sustainability of these efforts. PMID:22310813

  7. Review and Analysis of Development of "Safety by Design" Requirements

    SciTech Connect

    Vance, Scott A.; Hockert, John

    2009-10-20

    This report, the deliverable for Task 4 of the NA-243 Safeguards by Design Work Plan for Fiscal Year 2009, develops the lessons to be learned for the institutionalization of Safeguards By Design (SBD) from the Department of Energy (DOE) experience developing and implementing DOE-STD-1189, Integration of Safety into the Design Process. This experience was selected for study because of the similarity of the challenges of integrating safety and safeguards into the design process. Development of DOE-STD-1189 began in January 2006 and the standard was issued for implementation in March 2008. The process was much more time consuming than originally anticipated and might not have come to fruition had senior DOE management been less committed to its success. Potentially valuable lessons can be learned from both the content and presentation of the integration approach in DOE-STD-1189 and from the DOE experience in developing and implementing DOE-STD-1189. These lessons are important because the instutionalization of SBD does not yet appear to have the level of senior management commitment afforded development and implementation of DOE-STD-1189.

  8. A Putative Rhamnogalacturonase Required for Sexual Development of Neurospora Crassa

    PubMed Central

    Nelson, M. A.; Merino, S. T.; Metzenberg, R. L.

    1997-01-01

    In previous work, the asd-1 (ascus development) gene of the filamentous fungus Neurospora crassa was identified as a gene expressed preferentially during the sexual cycle and shown to be essential for normal sexual development. The asd-1 gene has been sequenced and further characterized. It contains two introns, the first of which is in-frame and inefficiently or differentially spliced. The predicted ASD-1 protein has extensive homology with rhamnogalacturonase B of Aspergillus aculeatus, which cleaves the backbone within the ramified hairy regions of pectin. In homozygous asd-1 crosses, sexual development is initiated and large numbers of normal-sized asci are formed. Ascospore delineation does not occur, however, and no sexual progeny are produced. As most asd-1 asci contain eight nuclei, the two meiotic divisions and subsequent mitotic division typical of normal crosses seem to occur, but the haploid nuclei are not partitioned into ascospores. In wild-type crosses, the ASD-1 protein is present in large amounts in croziers and young asci, but it is only faintly detectable in more mature asci containing developing ascospores. Models to explain the possible role of a rhamnogalacturonase in sexual development are presented. PMID:9178004

  9. 24 CFR 972.124 - Standards for identifying public housing developments subject to required conversion.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... housing developments subject to required conversion. 972.124 Section 972.124 Housing and Urban Development... INDIAN HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT CONVERSION OF PUBLIC HOUSING TO TENANT-BASED ASSISTANCE Required Conversion of Public Housing Developments Identifying Developments Subject to...

  10. 24 CFR 972.124 - Standards for identifying public housing developments subject to required conversion.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... housing developments subject to required conversion. 972.124 Section 972.124 Housing and Urban Development... INDIAN HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT CONVERSION OF PUBLIC HOUSING TO TENANT-BASED ASSISTANCE Required Conversion of Public Housing Developments Identifying Developments Subject to...

  11. 24 CFR 972.124 - Standards for identifying public housing developments subject to required conversion.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... housing developments subject to required conversion. 972.124 Section 972.124 Housing and Urban Development... INDIAN HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT CONVERSION OF PUBLIC HOUSING TO TENANT-BASED ASSISTANCE Required Conversion of Public Housing Developments Identifying Developments Subject to...

  12. 24 CFR 972.124 - Standards for identifying public housing developments subject to required conversion.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... housing developments subject to required conversion. 972.124 Section 972.124 Housing and Urban Development... INDIAN HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT CONVERSION OF PUBLIC HOUSING TO TENANT-BASED ASSISTANCE Required Conversion of Public Housing Developments Identifying Developments Subject to...

  13. 24 CFR 972.124 - Standards for identifying public housing developments subject to required conversion.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... housing developments subject to required conversion. 972.124 Section 972.124 Housing and Urban Development... INDIAN HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT CONVERSION OF PUBLIC HOUSING TO TENANT-BASED ASSISTANCE Required Conversion of Public Housing Developments Identifying Developments Subject to...

  14. Environmental management for dredging sediments - the requirement of developing nations.

    PubMed

    Manap, Norpadzlihatun; Voulvoulis, Nikolaos

    2015-01-01

    Scientific research has characterized the effects of dredging, an underwater excavation process for navigational purposes or material extraction, and has shown its association with a number of chemical, physical and biological impacts. Due to this, much environmental management has been applied in the dredging industry in order to manage its detrimental effects. However, developing nations may have different approaches towards their dredging environmental management to compare to their companions with higher economic strength. Moreover, scientific evidence to make an informed decision is often lacking, hence affecting the number of research executed at these nations, limiting their efforts to preserve the environment. This paper reviews the dredging environmental impacts and its two important factors, dredging technology and sediment characteristic, that determine the magnitude of impacts through literature review, and discusses the need for a more integrated dredging environmental management to be developed for developing nations. PMID:25304520

  15. Research requirements for development of regenerative engines for helicopters

    NASA Technical Reports Server (NTRS)

    Semple, R. D.

    1976-01-01

    The improved specific fuel consumption of the regenerative engine was compared to a simple-cycle turboshaft engine. The performance improvement and fuel saving are obtained at the expense of increased engine weight, development and production costs, and maintenance costs. Costs and schedules are estimated for the elements of the research and development program. Interaction of the regenerative engine with other technology goals for an advanced civil helicopter is examined, including its impact on engine noise, hover and cruise performance, helicopter empty weight, drive-system efficiency and weight, one-engine-inoperative hover capability, and maintenance and reliability.

  16. Resource Requirements and Costs of Developing and Delivering MOOCs

    ERIC Educational Resources Information Center

    Hollands, Fiona M.; Tirthali, Devayani

    2014-01-01

    Given the ongoing alarm regarding uncontrollable costs of higher education, it would be reasonable to expect not only concern about the impact of MOOCs on educational outcomes, but also systematic efforts to document the resources expended on their development and delivery. However, there is little publicly available information on MOOC costs that…

  17. 14 CFR 152.111 - Application requirements: Airport development.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Department of Housing and Urban Development as an area of special flood hazard as defined in the Flood... special flood hazard, a statement whether the community is participating in the National Flood Insurance... Transportation (49 CFR 25.57 and 25.59), whether or not reimbursement is being requested for the costs...

  18. 14 CFR 152.111 - Application requirements: Airport development.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Department of Housing and Urban Development as an area of special flood hazard as defined in the Flood... special flood hazard, a statement whether the community is participating in the National Flood Insurance... Transportation (49 CFR 25.57 and 25.59), whether or not reimbursement is being requested for the costs...

  19. 14 CFR 152.111 - Application requirements: Airport development.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Department of Housing and Urban Development as an area of special flood hazard as defined in the Flood... special flood hazard, a statement whether the community is participating in the National Flood Insurance... Transportation (49 CFR 25.57 and 25.59), whether or not reimbursement is being requested for the costs...

  20. YY1 Is Required for Germinal Center B Cell Development

    PubMed Central

    Vuyyuru, Raja; Jha, Vibha; Hodewadekar, Suchita; Manser, Tim; Atchison, Michael L.

    2016-01-01

    YY1 has been implicated as a master regulator of germinal center B cell development as YY1 binding sites are frequently present in promoters of germinal center-expressed genes. YY1 is known to be important for other stages of B cell development including the pro-B and pre-B cells stages. To determine if YY1 plays a critical role in germinal center development, we evaluated YY1 expression during B cell development, and used a YY1 conditional knock-out approach for deletion of YY1 in germinal center B cells (CRE driven by the immunoglobulin heavy chain γ1 switch region promoter; γ1-CRE). We found that YY1 is most highly expressed in germinal center B cells and is increased 3 fold in splenic B cells activated by treatment with anti-IgM and anti-CD40. In addition, deletion of the yy1 gene by action of γ1-CRE recombinase resulted in significant loss of GC cells in both un-immunized and immunized contexts with corresponding loss of serum IgG1. Our results show a crucial role for YY1 in the germinal center reaction. PMID:27167731

  1. Why a True Account of Human Development Requires Exemplar Research

    ERIC Educational Resources Information Center

    Damon, William; Colby, Anne

    2013-01-01

    This chapter uses moral psychology to illustrate why exemplar methods are essential for building a valid, complete understanding of key domains of human development. Social psychological, economic, and biological-evolutionary paradigms for studying morality rely on samples drawn from the general population. This research reveals a bleak picture of…

  2. Butcher, Baker, Candlestick Maker: Skills Required for Effective Multimedia Development.

    ERIC Educational Resources Information Center

    Hon, David

    1992-01-01

    Presents a matrix of skills necessary for multimedia development. Skills are identified in business, artistic, and technical areas. These skills are then applied to the following reasons for multimedia use: to condense time and material; to effect rapid skills transfer; and to manage feedback and evaluation. (MES)

  3. Commercialization is Required for Sustainable Space Exploration and Development

    NASA Technical Reports Server (NTRS)

    Martin, Gary L.; Olson, John M.

    2009-01-01

    The U.S. Space Exploration policy outlines an exciting new direction in space for human and robotic exploration and development beyond low Earth orbit. Pressed by this new visionary guidance, human civilization will be able to methodically build capabilities to move off Earth and into the solar system in a step-by-step manner, gradually increasing the capability for humans to stay longer in space and move further away from Earth. The new plans call for an implementation that would create an affordable and sustainable program in order to span over generations of explorers, each new generation pushing back the boundaries and building on the foundations laid by the earlier. To create a sustainable program it is important to enable and encourage the development of a selfsupporting commercial space industry leveraging both traditional and non-traditional segments of the industrial base. Governments will not be able to open the space frontier on their own because their goals change over relatively short timescales and because the large costs associated with human spaceflight cannot be sustained. A strong space development industrial sector is needed that can one day support the needs of commercial space enterprises as well as provide capabilities that the National Aeronautics and Space Administration (NASA) and other national space agencies can buy to achieve their exploration goals. This new industrial space sector will someday provide fundamental capabilities like communications, power, logistics, and even cargo and human space transportation, just as commercial companies are able to provide these services on Earth today. To help develop and bolster this new space industrial sector, NASA and other national space agencies can enable and facilitate it in many ways, including reducing risk by developing important technologies necessary for commercialization of space, and as a paying customer, partner, or anchor tenant. This transition from all or mostly government

  4. Developing doctoral scientists for drug discovery: pluridimensional education required.

    PubMed

    Janero, David R

    2013-02-01

    Research universities continue to produce new scientists capable of generating knowledge with the potential to inform disease etiology and treatment. Mounting interest of doctoral-level experimental science students in therapeutics-related research careers is discordant with the widespread lack of direct drug-discovery and development experience, let alone commercialization success, among university faculty and administrators. Likewise, the archetypical publication- and grant-fueled, principal investigator (PI)-focused academic system ("PI-stan") risks commoditization of science students pursuing their doctorates as a labor source, rendering them ill-prepared for career options related to therapeutics innovation by marginalizing their development of "beyond-the-bench" professional skills foundational to modern drug-discovery campaigns and career fluency. To militate against professionalization deficits in doctoral drug-discovery researchers, the author--a scientist-administrator-consultant with decades of discovery research and development (R&D), business, and educator experience in commercial and university settings--posits a critical need for pluridimensionality in graduate education and mentorship that extends well beyond thesis-related scientific domains/laboratory techniques to instill transferable operational-intelligence, project/people-management, and communication competencies. Specific initiatives are advocated to help enhance the doctoral science student's market competitiveness, adaptability, and navigation of the significant research, commercial, and occupational challenges associated with contemporary preclinical drug-discovery R&D. PMID:23231364

  5. Developing clinical guidelines: how much rigour is required?

    PubMed

    Haroon, Munib; Ranmal, Rita; McElroy, Helen; Dudley, Jan

    2015-04-01

    Clinical guidelines that are rigorously developed play a fundamental role in improving healthcare and reducing unnecessary variations in practice. National guidelines are increasingly used by healthcare professionals, patients and commissioners; however, national bodies are unable to meet the demand for guidance on all topics. There are fewer resources available for guidance produced locally or by specialty groups, and it is necessary to achieve a balance between pragmatism and rigour while conforming to the widely accepted norms of what constitutes a good guideline. This paper introduces the key concepts around this topic with suggestions for those interested in developing their own guideline. An example of challenges encountered in generating high-quality clinical guidance is given in box 1. Box 1 Challenges in guideline development Professor Johnson runs a local developmental paediatrics service with eight other colleagues. All have different ways of managing children with PAVING syndrome. This was difficult for patients and staff and has led to disagreements on how certain patients should be managed. As a result, Professor Johnson developed a Guideline Development Group to look at the management of PAVING syndrome. The group identified 12 clinical questions (including diagnosis, exclusion of comorbidities, treatment modalities), searched the PubMed database and found some useful evidence that they used to formulate key recommendations. For one question about behavioural therapy, PubMed did not suggest any evidence so they informally arrived at a consensus among themselves and wrote up their guideline. On the back of this success, they applied for the guideline to be endorsed or supported by the Royal College of Paediatrics and Child Health (RCPCH). To their frustration, it was turned down on methodological grounds. Professor Johnson wrote to the RCPCH saying that he was "pretty peeved that the PAVING syndrome guideline had been rejected" for the College

  6. Requirements for future development of small scale rainfall simulators

    NASA Astrophysics Data System (ADS)

    Iserloh, Thomas; Ries, Johannes B.; Seeger, Manuel

    2013-04-01

    Rainfall simulation with small scale simulators is a method used worldwide to assess the generation of overland flow, soil erosion, infiltration and interrelated processes such as soil sealing, crusting, splash and redistribution of solids and solutes. Following the outcomes of the project "Comparability of simulation results of different rainfall simulators as input data for soil erosion modelling (Deutsche Forschungsgemeinschaft - DFG, Project No. Ri 835/6-1)" and the "International Rainfall Simulator Workshop 2011" in Trier, the necessity for further technical improvements of simulators and strategies towards an adaption of designs and methods becomes obvious. Uniform measurements of artificially generated rainfall and comparative measurements on a prepared bare fallow with rainfall simulators used by European research groups showed limitations of the comparability of the results. The following requirements, essential for small portable rainfall simulators, were identified: (I) Low and efficient water consumption for use in areas with water shortage, (II) easy handling and control of test conditions, (III) homogeneous spatial rainfall distribution, (IV) best possible drop spectrum (physically), (V) reproducibility and knowledge of spatial distribution and drop spectrum, (VI) easy and fast training of operators to obtain reproducible experiments and (VII) good mobility and easy installation for use in remote areas and in regions where highly erosive rainfall events are rare or irregular. The presentation discusses possibilities for a common use of identical plot designs, rainfall intensities and nozzles.

  7. Tissue homogeneity requires inhibition of unequal gene silencing during development.

    PubMed

    Le, Hai H; Looney, Monika; Strauss, Benjamin; Bloodgood, Michael; Jose, Antony M

    2016-08-01

    Multicellular organisms can generate and maintain homogenous populations of cells that make up individual tissues. However, cellular processes that can disrupt homogeneity and how organisms overcome such disruption are unknown. We found that ∼100-fold differences in expression from a repetitive DNA transgene can occur between intestinal cells in Caenorhabditis elegans These differences are caused by gene silencing in some cells and are actively suppressed by parental and zygotic factors such as the conserved exonuclease ERI-1. If unsuppressed, silencing can spread between some cells in embryos but can be repeat specific and independent of other homologous loci within each cell. Silencing can persist through DNA replication and nuclear divisions, disrupting uniform gene expression in developed animals. Analysis at single-cell resolution suggests that differences between cells arise during early cell divisions upon unequal segregation of an initiator of silencing. Our results suggest that organisms with high repetitive DNA content, which include humans, could use similar developmental mechanisms to achieve and maintain tissue homogeneity. PMID:27458132

  8. Management of incompletely developed teeth requiring root canal treatment.

    PubMed

    Harlamb, S C

    2016-03-01

    Endodontic management of the permanent immature tooth continues to be a challenge for both clinicians and researchers. Clinical concerns are primarily related to achieving adequate levels of disinfection as 'aggressive' instrumentation is contraindicated and hence there exists a much greater reliance on endodontic irrigants and medicaments. The open apex has also presented obturation difficulties, notably in controlling length. Long-term apexification procedures with calcium hydroxide have proven to be successful in retaining many of these immature infected teeth but due to their thin dentinal walls and perceived problems associated with long-term placement of calcium hydroxide, they have been found to be prone to cervical fracture and subsequent tooth loss. In recent years there has developed an increasing interest in the possibility of 'regenerating' pulp tissue in an infected immature tooth. It is apparent that although the philosophy and hope of 'regeneration' is commendable, recent histologic studies appear to suggest that the calcified material deposited on the canal wall is bone/cementum rather than dentine, hence the absence of pulp tissue with or without an odontoblast layer. PMID:26923451

  9. REQUEST FOR APPLICATIONS FOR A COOPERATIVE AGREEMENT TO PROVIDE ASSISTANCE FOR CONDUCTING RESEARCH TO DEVELOP IMPROVED METHODS AND APPROACHES TO EMPOWER COMMUNITIES TO PARTICIPATE MORE EFFECTIVELY IN ENVIRONMENTAL CLEANUPS

    EPA Science Inventory

    The Environmental Protection Agency (EPA), Office of Research and Development, National Center for Environmental Assessment (NCEA) is issuing this Request for Applications (RFA) for cooperative agreements to provide assistance conducting research to stimulate advances in the scie...

  10. Development of a Stochastic Inversion Tool To Optimize Agreement Between The Observed And Predicted Seismic Response To CO2 Injection/Migration in the Weyburn-Midale Project

    SciTech Connect

    Ramirez, A L; Hao, Y; White, D; Carle, S; Dyer, K; Yang, X; Mcnab, W; Foxall, W; Johnson, J

    2009-12-02

    During Phase 1 of the Weyburn Project (2000-2004), 4D reflection seismic data were used to map CO{sub 2} migration within the Midale reservoir, while an extensive fluid sampling program documented the geochemical evolution triggered by CO{sub 2}-brine-oil-mineral interactions. The aim of this task (3b.11) is to exploit these existing seismic and geochemical data sets, augmented by CO{sub 2}/H{sub 2}O injection and HC/H{sub 2}O production data toward optimizing the reservoir model and thereby improving site characterization and dependent predictions of long-term CO{sub 2} storage in the Weyburn-Midale reservoir. Our initial project activities have concentrated on developing a stochastic inversion method that will identify reservoir models that optimize agreement between the observed and predicted seismic response. This report describes the technical approach we have followed, the data that supports it, and associated implementation activities. The report fulfills deliverable D1 in the project's statement of work. Future deliverables will describe the development of the stochastic inversion tool that uses geochemical data to optimize the reservoir model.

  11. 24 CFR 972.115 - Relationship between required conversions and HOPE VI developments.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... conversions and HOPE VI developments. 972.115 Section 972.115 Housing and Urban Development REGULATIONS... Relationship between required conversions and HOPE VI developments. HUD actions to approve or deny proposed HOPE VI revitalization plans must be consistent with the requirements of this subpart....

  12. 24 CFR 972.115 - Relationship between required conversions and HOPE VI developments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... conversions and HOPE VI developments. 972.115 Section 972.115 Housing and Urban Development Regulations... Relationship between required conversions and HOPE VI developments. HUD actions to approve or deny proposed HOPE VI revitalization plans must be consistent with the requirements of this subpart....

  13. 24 CFR 972.115 - Relationship between required conversions and HOPE VI developments.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... conversions and HOPE VI developments. 972.115 Section 972.115 Housing and Urban Development REGULATIONS... Relationship between required conversions and HOPE VI developments. HUD actions to approve or deny proposed HOPE VI revitalization plans must be consistent with the requirements of this subpart....

  14. 24 CFR 972.115 - Relationship between required conversions and HOPE VI developments.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... conversions and HOPE VI developments. 972.115 Section 972.115 Housing and Urban Development REGULATIONS... Relationship between required conversions and HOPE VI developments. HUD actions to approve or deny proposed HOPE VI revitalization plans must be consistent with the requirements of this subpart....

  15. 24 CFR 972.115 - Relationship between required conversions and HOPE VI developments.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... conversions and HOPE VI developments. 972.115 Section 972.115 Housing and Urban Development REGULATIONS... Relationship between required conversions and HOPE VI developments. HUD actions to approve or deny proposed HOPE VI revitalization plans must be consistent with the requirements of this subpart....

  16. 43 CFR 3483.1 - Diligent development and continued operation requirement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Diligent development and continued... AND MINING OPERATIONS RULES Diligence Requirements § 3483.1 Diligent development and continued..., each Federal coal lease and LMU is required to achieve diligent development. (2) Once the...

  17. Mining agreements III

    SciTech Connect

    Not Available

    1991-01-01

    This book cover the following: Forms of mining agreements; Preliminary letter agreements; Acquisition of mineral interests involving securities; Partnership tax treatment in mining agreements; Non-tax consequences of partnerships under state law; Protection against joint venturers' liabilities; Joint venture decision making; Mining royalties; Commingling and unitization provisions; Indemnification and insurance provisions; Area of interest provision; Dispute resolution; and Non-participation and default provisions.

  18. The Bottom-up Move within Vygotsky's Zone of Proximal Development: A Pedagogical Application for Teaching Agreement in Spanish as a Foreign Language

    ERIC Educational Resources Information Center

    Escandon, Arturo; Sanz, Montserrat

    2011-01-01

    This paper presents the findings of a longitudinal study in which two instructional methods to teach agreement features to first-year university students specializing in Spanish in Japan are compared. On the one hand, the control group was exposed to the traditional top-down teaching of agreement paradigms and were instructed to practice them…

  19. Misinterpretations in agreement and agreement attraction.

    PubMed

    Patson, Nikole D; Husband, E Matthew

    2016-05-01

    It has been well established that subject-verb number agreement can be disrupted by local noun phrases that differ in number from the subject head noun phrase. In sentence production, mismatches in the grammatical number of the head and local noun phrases lead to agreement errors on the verb as in: the key to the cabinets are. Similarly, although ungrammaticality typically causes disruption in measures of sentence comprehension, the disruption is reduced when the local noun phrase has a plural feature. Using a forced-choice comprehension question method, we report two experiments that provide evidence that comprehenders were likely to misinterpret the number information on the head noun phrase when morphosyntactic number markings on the local noun phrase and verb did not match the head. These results are consistent with a growing body of research that suggests that comprehenders often arrive at a final interpretation of a sentence that is not faithful to the linguistic input. PMID:25624171

  20. The study on knowledge transferring incentive for information system requirement development

    SciTech Connect

    Li, Yang

    2015-03-10

    Information system requirement development is a process of users’ knowledge sharing and transferring. However the tacit requirements developing is a main problem during requirement development process, for the reason of difficult to encoding, express, and communicate. Knowledge fusion and corporate effort is needed to finding tacit requirements. Under this background, our paper try to find out the rule of effort dynamic evolutionary of software developer and user by building an evolutionary game model on the condition of incentive system. And in addition this paper provides an in depth discussion at the end of this paper.

  1. Affiliate Agreements in Community Mental Health: Shotgun Weddings?

    ERIC Educational Resources Information Center

    Kane, Thomas J.; Meyer, James, Jr.

    1980-01-01

    The development of affiliate agreements requires an organized and planned approach with specific goals and strategies, taking into account the complex dynamics that operate in inter-organizational relationships. Successful negotiation leads to decisions in the best interest of each partner, not just preservation of the relationship. (JAC)

  2. 43 CFR 414.3 - Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF... of the requirements of this section. (1) The agreement must specify the quantity of Colorado River... that the Storing State's consumptive use of Colorado River water will be decreased by a...

  3. 43 CFR 414.3 - Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF... of the requirements of this section. (1) The agreement must specify the quantity of Colorado River... that the Storing State's consumptive use of Colorado River water will be decreased by a...

  4. 43 CFR 414.3 - Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF... of the requirements of this section. (1) The agreement must specify the quantity of Colorado River... that the Storing State's consumptive use of Colorado River water will be decreased by a...

  5. 43 CFR 414.3 - Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF... of the requirements of this section. (1) The agreement must specify the quantity of Colorado River... that the Storing State's consumptive use of Colorado River water will be decreased by a...

  6. 43 CFR 414.3 - Storage and Interstate Release Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF... of the requirements of this section. (1) The agreement must specify the quantity of Colorado River... that the Storing State's consumptive use of Colorado River water will be decreased by a...

  7. Gender agreement and multiple referents

    PubMed Central

    Finocchiaro, Chiara; Mahon, Bradford Z.; Caramazza, Alfonso

    2010-01-01

    We report a new pattern of usage in current, spoken Italian that has implications for both psycholinguistic models of language production and linguistic theories of language change. In Italian, gender agreement is mandatory for both singular and plural nouns. However, when two or more nouns of different grammatical gender appear in a conjoined noun phrase (NP), masculine plural agreement is required. In this study, we combined on-line and off-line methodologies in order to assess the mechanisms involved in gender marking in the context of multiple referents. The results of two pronoun production tasks showed that plural feminine agreement was significantly more difficult than plural masculine agreement. In a separate study using offline judgements of acceptability, we found that agreement violations in Italian are tolerated more readily in the case of feminine conjoined noun phrases (e.g., la mela e la banana ‘the:fem apple:fem and the: fem banana: fem’) than masculine conjoined noun phrases (e.g., il fiore e il libro ‘the:mas flower: mas and the:mas book:mas’). Implications of these results are discussed both at the level of functional architecture within the language production system and at the level of changes in language use.* PMID:21037930

  8. 24 CFR 583.400 - Grant agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 3 2011-04-01 2010-04-01 true Grant agreement. 583.400 Section 583.400 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... DEVELOPMENT COMMUNITY FACILITIES SUPPORTIVE HOUSING PROGRAM Administration § 583.400 Grant agreement....

  9. 24 CFR 583.400 - Grant agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 3 2013-04-01 2013-04-01 false Grant agreement. 583.400 Section 583.400 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... DEVELOPMENT COMMUNITY FACILITIES SUPPORTIVE HOUSING PROGRAM Administration § 583.400 Grant agreement....

  10. 24 CFR 583.400 - Grant agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Grant agreement. 583.400 Section 583.400 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... DEVELOPMENT COMMUNITY FACILITIES SUPPORTIVE HOUSING PROGRAM Administration § 583.400 Grant agreement....

  11. 24 CFR 583.400 - Grant agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 3 2014-04-01 2013-04-01 true Grant agreement. 583.400 Section 583.400 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... DEVELOPMENT COMMUNITY FACILITIES SUPPORTIVE HOUSING PROGRAM Administration § 583.400 Grant agreement....

  12. Non-Proliferation Agreements.

    ERIC Educational Resources Information Center

    Swalec, John J.

    1981-01-01

    Discusses five kinds of cooperative agreements established by the College of Lake County (IL): those with other community colleges/technical institutes; the military; business, industry, and organizations; secondary schools; and community and special interest groups. Pays particular attention to two kinds of agreements with other colleges. (CAM)

  13. Cooperative Agreements Study Report.

    ERIC Educational Resources Information Center

    Lawton, R. E.; Magruder, D.

    During the 1983 meeting of the Florida Legislature, action was taken to begin a systematic study of the level of cooperation between the Florida public schools K-12 program and the community and junior colleges. The goals and objectives of the Cooperative Agreements Study were to review and compile a list of the cooperative agreements and identify…

  14. USA/FRG umbrella agreement for cooperation in gas-cooled reactor development: Subprogram plan for cooperation in AVR [Arbeitsgemeinschaft Versuchs Reaktor] Test Program

    SciTech Connect

    Cleveland, J C; Baxter, A M; Krueger, K

    1988-05-01

    This subprogram plan describes cooperative work related to the AVR Test Program. This cooperative work is being carried out under the USA/FRG Implementing Agreement for Cooperation in Gas-Cooled Reactor Development. Earlier cooperation in this area was conducted under the Project Work Statement (PWS) for the ORNL/KFA/AVR Cooperative Effort in HTR Physics, Performance and Safety. The purpose of the cooperation is to obtain experimental information from the AVR relevant to the performance and safety of modular gas-cooled reactors, and to compare measured results with predictions of analytical tools. The scope of the cooperation involves examining the behavior of the AVR under various planned test conditions pertinent to modular gas-cooled reactor performance. AVR test data will be utilized to help validate computational methods used in the areas of reactor physics, fission and activation product transport and plant transient response, and to help understand modular gas-cooled reactor safety behavior (e.g., fission product behavior, dust behavior, and thermofluid dynamic behavior).

  15. 48 CFR 35.004 - Publicizing requirements and expanding research and development sources.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Publicizing requirements and expanding research and development sources. 35.004 Section 35.004 Federal Acquisition Regulations... CONTRACTING 35.004 Publicizing requirements and expanding research and development sources. (a) In order...

  16. 48 CFR 35.004 - Publicizing requirements and expanding research and development sources.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Publicizing requirements and expanding research and development sources. 35.004 Section 35.004 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.004 Publicizing requirements...

  17. 12 CFR 723.3 - What are the requirements for construction and development lending?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false What are the requirements for construction and development lending? 723.3 Section 723.3 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS MEMBER BUSINESS LOANS § 723.3 What are the requirements for construction and development lending? Except as...

  18. Requirements Development Issues for Advanced Life Support Systems: Solid Waste Management

    NASA Technical Reports Server (NTRS)

    Levri, Julie A.; Fisher, John W.; Alazraki, Michael P.; Hogan, John A.

    2002-01-01

    Long duration missions pose substantial new challenges for solid waste management in Advanced Life Support (ALS) systems. These possibly include storing large volumes of waste material in a safe manner, rendering wastes stable or sterilized for extended periods of time, and/or processing wastes for recovery of vital resources. This is further complicated because future missions remain ill-defined with respect to waste stream quantity, composition and generation schedule. Without definitive knowledge of this information, development of requirements is hampered. Additionally, even if waste streams were well characterized, other operational and processing needs require clarification (e.g. resource recovery requirements, planetary protection constraints). Therefore, the development of solid waste management (SWM) subsystem requirements for long duration space missions is an inherently uncertain, complex and iterative process. The intent of this paper is to address some of the difficulties in writing requirements for missions that are not completely defined. This paper discusses an approach and motivation for ALS SWM requirements development, the characteristics of effective requirements, and the presence of those characteristics in requirements that are developed for uncertain missions. Associated drivers for life support system technological capability are also presented. A general means of requirements forecasting is discussed, including successive modification of requirements and the need to consider requirements integration among subsystems.

  19. Sexual Agreements among Gay Male Couples

    PubMed Central

    Hoff, Colleen H.; Beougher, Sean C.

    2009-01-01

    Many gay male couples make agreements about whether or not to permit sex with outside partners, yet little is known about the development and maintenance of these agreements, their impact on relationships, and whether they are an effective HIV prevention strategy. Using semi-structured, qualitative interviews, 39 gay male couples were asked about their sexual agreements and about other relationship dynamics that might affect their agreements. Analysis revealed a wide range of agreement types, all of which are presented along a continuum rather than as discrete categories. For couples with open agreements, most placed rules or conditions limiting when, where, how often, and with whom outside sex was permitted. Although motivations for having agreements varied, HIV prevention did not rank as a primary factor for any couple. Most couples had congruous agreements; however, a small number reported discrepancies which may increase HIV transmission risk. How couples handled breaks in their agreements also varied, depending on what condition was broken, whether it was disclosed, and the partner's reaction. Additional results include differences in agreement type and motivations for having an agreement based on couple serostatus. Overall, agreements benefited couples by providing boundaries for the relationship, supporting a non-heteronormative identity, and fulfilling the sexual needs of the couple. Future prevention efforts involving gay couples must address the range of agreement types and the meanings couples ascribe to them, in addition to tempering safety messages with the relationship issues that are important to and faced by gay couples. PMID:18686027

  20. 24 CFR 968.102 - Special requirements for Turnkey III developments.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Special requirements for Turnkey III developments. 968.102 Section 968.102 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN...

  1. 24 CFR 968.102 - Special requirements for Turnkey III developments.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Special requirements for Turnkey III developments. 968.102 Section 968.102 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN...

  2. 24 CFR 968.102 - Special requirements for Turnkey III developments.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Special requirements for Turnkey III developments. 968.102 Section 968.102 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN...

  3. 24 CFR 968.102 - Special requirements for Turnkey III developments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Special requirements for Turnkey III developments. 968.102 Section 968.102 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN...

  4. 13 CFR 303.7 - Requirements for Comprehensive Economic Development Strategies.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Economic Development Strategies. 303.7 Section 303.7 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT OF COMMERCE PLANNING INVESTMENTS AND COMPREHENSIVE ECONOMIC DEVELOPMENT STRATEGIES § 303.7 Requirements for Comprehensive Economic Development Strategies. (a) General. CEDS are...

  5. 13 CFR 303.7 - Requirements for Comprehensive Economic Development Strategies.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Economic Development Strategies. 303.7 Section 303.7 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT OF COMMERCE PLANNING INVESTMENTS AND COMPREHENSIVE ECONOMIC DEVELOPMENT STRATEGIES § 303.7 Requirements for Comprehensive Economic Development Strategies. (a) General. CEDS are...

  6. 13 CFR 303.7 - Requirements for Comprehensive Economic Development Strategies.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Economic Development Strategies. 303.7 Section 303.7 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT OF COMMERCE PLANNING INVESTMENTS AND COMPREHENSIVE ECONOMIC DEVELOPMENT STRATEGIES § 303.7 Requirements for Comprehensive Economic Development Strategies. (a) General. CEDS are...

  7. Agreement in cardiovascular risk rating based on anthropometric parameters

    PubMed Central

    Dantas, Endilly Maria da Silva; Pinto, Cristiane Jordânia; Freitas, Rodrigo Pegado de Abreu; de Medeiros, Anna Cecília Queiroz

    2015-01-01

    Objective To investigate the agreement in evaluation of risk of developing cardiovascular diseases based on anthropometric parameters in young adults. Methods The study included 406 students, measuring weight, height, and waist and neck circumferences. Waist-to-height ratio and the conicity index. The kappa coefficient was used to assess agreement in risk classification for cardiovascular diseases. The positive and negative specific agreement values were calculated as well. The Pearson chi-square (χ2) test was used to assess associations between categorical variables (p<0.05). Results The majority of the parameters assessed (44%) showed slight (k=0.21 to 0.40) and/or poor agreement (k<0.20), with low values of negative specific agreement. The best agreement was observed between waist circumference and waist-to-height ratio both for the general population (k=0.88) and between sexes (k=0.93 to 0.86). There was a significant association (p<0.001) between the risk of cardiovascular diseases and females when using waist circumference and conicity index, and with males when using neck circumference. This resulted in a wide variation in the prevalence of cardiovascular disease risk (5.5%-36.5%), depending on the parameter and the sex that was assessed. Conclusion The results indicate variability in agreement in assessing risk for cardiovascular diseases, based on anthropometric parameters, and which also seems to be influenced by sex. Further studies in the Brazilian population are required to better understand this issue. PMID:26466060

  8. Program management plan for development, demonstration, testing, and evaluation efforts associated with Oak Ridge Reservation`s Land Disposal Restrictions Federal Facility Compliance Agreement

    SciTech Connect

    Conley, T.B.

    1994-04-01

    This program management plan covers the development, demonstration, testing, and evaluation efforts necessary to identify treatment methods for all the waste listed in Appendix B of the ORR`s LDR/FFCA as well as any new wastes which meet Appendix B criteria. To successfully identify a treatment method, at least a proof-of-principle level of understanding must be obtained: that is, the candidate processes must be demonstrated as effective in treating the wastes to the LDR; however, an optimized process is not required. Where applicable and deemed necessary and where the budgets will support them, pilot-scale demonstrations will be pursued. The overall strategy being adopted in this program will be composed of the following activities: Scoping of the study; characterization; development and screening of alternatives; treatability investigations; and detailed analysis of alternatives.

  9. Designing eHealth that Matters via a Multidisciplinary Requirements Development Approach

    PubMed Central

    Wentzel, Jobke; Van Gemert-Pijnen, Julia EWC

    2013-01-01

    Background Requirements development is a crucial part of eHealth design. It entails all the activities devoted to requirements identification, the communication of requirements to other developers, and their evaluation. Currently, a requirements development approach geared towards the specifics of the eHealth domain is lacking. This is likely to result in a mismatch between the developed technology and end user characteristics, physical surroundings, and the organizational context of use. It also makes it hard to judge the quality of eHealth design, since it makes it difficult to gear evaluations of eHealth to the main goals it is supposed to serve. Objective In order to facilitate the creation of eHealth that matters, we present a practical, multidisciplinary requirements development approach which is embedded in a holistic design approach for eHealth (the Center for eHealth Research roadmap) that incorporates both human-centered design and business modeling. Methods Our requirements development approach consists of five phases. In the first, preparatory, phase the project team is composed and the overall goal(s) of the eHealth intervention are decided upon. Second, primary end users and other stakeholders are identified by means of audience segmentation techniques and our stakeholder identification method. Third, the designated context of use is mapped and end users are profiled by means of requirements elicitation methods (eg, interviews, focus groups, or observations). Fourth, stakeholder values and eHealth intervention requirements are distilled from data transcripts, which leads to phase five, in which requirements are communicated to other developers using a requirements notation template we developed specifically for the context of eHealth technologies. Results The end result of our requirements development approach for eHealth interventions is a design document which includes functional and non-functional requirements, a list of stakeholder values, and end

  10. 48 CFR 31.109 - Advance agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) Statistical sampling methods (see 31.201-6(c)(4). ... contractors should seek advance agreement on the treatment of special or unusual costs and on statistical sampling methodologies at 31.201-6(c). However, an advance agreement is not an absolute requirement and...

  11. 48 CFR 31.109 - Advance agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) Statistical sampling methods (see 31.201-6(c)(4). ... contractors should seek advance agreement on the treatment of special or unusual costs and on statistical sampling methodologies at 31.201-6(c). However, an advance agreement is not an absolute requirement and...

  12. 48 CFR 31.109 - Advance agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) Statistical sampling methods (see 31.201-6(c)(4). ... contractors should seek advance agreement on the treatment of special or unusual costs and on statistical sampling methodologies at 31.201-6(c). However, an advance agreement is not an absolute requirement and...

  13. 36 CFR 254.14 - Exchange agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... required congressional oversight; (6) In the event of an appeal under 36 CFR part 215 or 36 CFR part 251... agreement. (c) In the event of a failure to perform or to comply with the terms of an exchange agreement..., title searches, title curative actions, cultural resource surveys and mitigation, hazardous...

  14. 7 CFR Exhibit B to Subpart C of... - Site Development Design Requirements

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 12 2011-01-01 2011-01-01 false Site Development Design Requirements B Exhibit B to... OF AGRICULTURE PROGRAM REGULATIONS CONSTRUCTION AND REPAIR Planning and Performing Site Development Work Pt. 1924, Subpt. C, Exh. B Exhibit B to Subpart C of Part 1924—Site Development...

  15. 7 CFR Exhibit B to Subpart C of... - Site Development Design Requirements

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 12 2013-01-01 2013-01-01 false Site Development Design Requirements B Exhibit B to... OF AGRICULTURE PROGRAM REGULATIONS CONSTRUCTION AND REPAIR Planning and Performing Site Development Work Pt. 1924, Subpt. C, Exh. B Exhibit B to Subpart C of Part 1924—Site Development...

  16. 7 CFR Exhibit B to Subpart C of... - Site Development Design Requirements

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 12 2012-01-01 2012-01-01 false Site Development Design Requirements B Exhibit B to... OF AGRICULTURE PROGRAM REGULATIONS CONSTRUCTION AND REPAIR Planning and Performing Site Development Work Pt. 1924, Subpt. C, Exh. B Exhibit B to Subpart C of Part 1924—Site Development...

  17. 7 CFR Exhibit B to Subpart C of... - Site Development Design Requirements

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 12 2014-01-01 2013-01-01 true Site Development Design Requirements B Exhibit B to... OF AGRICULTURE PROGRAM REGULATIONS CONSTRUCTION AND REPAIR Planning and Performing Site Development Work Pt. 1924, Subpt. C, Exh. B Exhibit B to Subpart C of Part 1924—Site Development...

  18. 48 CFR 35.004 - Publicizing requirements and expanding research and development sources.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... and expanding research and development sources. 35.004 Section 35.004 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.004 Publicizing requirements and expanding research and development sources. (a) In order...

  19. 48 CFR 35.004 - Publicizing requirements and expanding research and development sources.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... and expanding research and development sources. 35.004 Section 35.004 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.004 Publicizing requirements and expanding research and development sources. (a) In order...

  20. 48 CFR 752.7005 - Submission requirements for development experience documents.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... for development experience documents. 752.7005 Section 752.7005 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of USAID Contract Clauses 752.7005 Submission requirements for development experience documents....

  1. Effects of School Heads' and Teachers' Agreement with the Curriculum Reform on Curriculum Development Progress and Student Learning in Hong Kong

    ERIC Educational Resources Information Center

    Cheung, Alan C. K.; Wong, Ping Man

    2011-01-01

    Purpose: The purpose of this paper is to examine the progress of the curriculum reform in Hong Kong in the implementation phase from 2001-2006, with the agreement and support of heads and teachers on the reform. Design/methodology/approach: Survey questionnaires and focus group interviews were used to collect data from various stakeholders. A…

  2. 46 CFR Sec. 3 - Standby agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... United States, or other requirements of the nation's defense. In such cases, the contractor accepts the... States, or other requirements of the nation's defense. An agreement executed after the deployment of the Armed Forces of the United States, or other requirements of the nation's defense may be operational...

  3. 30 CFR 254.53 - Submitting a response plan developed under State requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Submitting a response plan developed under State requirements. 254.53 Section 254.53 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL-SPILL RESPONSE REQUIREMENTS FOR FACILITIES LOCATED SEAWARD OF THE COAST LINE Oil-Spill...

  4. 12 CFR 723.3 - What are the requirements for construction and development lending?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false What are the requirements for construction and... AFFECTING CREDIT UNIONS MEMBER BUSINESS LOANS § 723.3 What are the requirements for construction and... granted for the construction or development of commercial or residential property are subject to...

  5. 48 CFR 16.703 - Basic ordering agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... agreements may need to be revised before the annual review due to mandatory statutory requirements. A basic... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Basic ordering agreements... CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Agreements 16.703 Basic ordering agreements....

  6. Analysis of requirements for accelerating the development of geothermal energy resources in California

    NASA Technical Reports Server (NTRS)

    Fredrickson, C. D.

    1978-01-01

    Various resource data are presented showing that geothermal energy has the potential of satisfying a singificant part of California's increasing energy needs. General factors slowing the development of geothermal energy in California are discussed and required actions to accelerate its progress are presented. Finally, scenarios for developing the most promising prospects in the state directed at timely on-line power are given. Specific actions required to realize each of these individual scenarios are identified.

  7. Design requirements and development of an airborne descent path definition algorithm for time navigation

    NASA Technical Reports Server (NTRS)

    Izumi, K. H.; Thompson, J. L.; Groce, J. L.; Schwab, R. W.

    1986-01-01

    The design requirements for a 4D path definition algorithm are described. These requirements were developed for the NASA ATOPS as an extension of the Local Flow Management/Profile Descent algorithm. They specify the processing flow, functional and data architectures, and system input requirements, and recommended the addition of a broad path revision (reinitialization) function capability. The document also summarizes algorithm design enhancements and the implementation status of the algorithm on an in-house PDP-11/70 computer. Finally, the requirements for the pilot-computer interfaces, the lateral path processor, and guidance and steering function are described.

  8. 76 FR 61597 - Grants and Cooperative Agreements to State and Local Governments: DOT Amendments on Regulations...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ... and Agreements With Institutions of Higher Education, Hospitals and Other Non-Profit Organizations... Agreements to State and Local Governments; Grants and Agreements with Institutions of Higher Education... uniform administrative requirements for grants and agreements with Institutions of Higher...

  9. FFTF Authorization Agreement

    SciTech Connect

    DAUTEL, W.A.

    2000-02-25

    The purpose of the Authorization Agreement is to serve as a mechanism whereby the U.S. Department of Energy, Richland Operations Office (RL) and Fluor Hanford (FH) jointly clarify and agree to key conditions for conducting work safely and efficiently.

  10. Coefficients for Interrater Agreement.

    ERIC Educational Resources Information Center

    Zegers, Frits E.

    1991-01-01

    The degree of agreement between two raters rating several objects for a single characteristic can be expressed through an association coefficient, such as the Pearson product-moment correlation. How to select an appropriate association coefficient, and the desirable properties and uses of a class of such coefficients--the Euclidean…

  11. Development of Regulatory Technical Requirements for the Advanced Integral Type Research Reactor

    SciTech Connect

    Jo, Jong Chull; Yune, Young Gill; Kim, Woong Sik; Kim, Hho Jung

    2004-07-01

    This paper presents the current status of the study on the development of regulatory technical requirements for the licensing review of an advanced integral type research reactor of which the license application is expected in a few years. According to the Atomic Energy Act of Korea, both research and education reactors are subject to the technical requirements for power reactors in the licensing review. But, some of the requirements may not be applicable or insufficient for the licensing reviews of reactors with unique design features. Thus it is necessary to identify which review topics or areas can not be addressed by the existing requirements and to develop the required ones newly or supplement appropriately. Through the study performed so far, it has been identified that the following requirements need to be developed newly for the licensing review of SMART-P: the use of proven technology, the interfacial facility, the non-safety systems, and the metallic fuels. The approach and basis for the development of each of the requirements are discussed. (authors)

  12. Canadian seismic agreement

    SciTech Connect

    Wetmiller, R.J.; Lyons, J.A.; Shannon, W.E.; Munro, P.S.; Thomas, J.T.; Andrew, M.D.; Lamontagne, M.; Wong, C.; Anglin, F.M.; Plouffe, M.; Adams, J.; Drysdale, J.A. . Geophysics Div.)

    1990-04-01

    During the period of this report, the contract resources were spent on operation and maintenance of the Eastern Canada Telemetred Network (ECTN), development of special purpose local network systems, servicing and maintenance of the strong-motion seismograph network in eastern Canada, operation of the Ottawa data lab and earthquake monitoring and reporting. Of special note in this period was the final completion of the Sudbury (SLTN) and Charlevoix (CLTN) local networks and the integration of their data processing and analysis requirements in the regular analysis stream for ECTN data. These networks now acquire high quality digital data for detailed analysis of seismic activity and source properties from these two areas, thus effectively doubling the amount of seismic data being received by the Ottawa data lab. 37 refs., 17 figs., 2 tabs.

  13. Experimental development based on mapping rule between requirements analysis model and web framework specific design model.

    PubMed

    Okuda, Hirotaka; Ogata, Shinpei; Matsuura, Saeko

    2013-12-01

    Model Driven Development is a promising approach to develop high quality software systems. We have proposed a method of model-driven requirements analysis using Unified Modeling Language (UML). The main feature of our method is to automatically generate a Web user interface prototype from UML requirements analysis model so that we can confirm validity of input/output data for each page and page transition on the system by directly operating the prototype. We proposes a mapping rule in which design information independent of each web application framework implementation is defined based on the requirements analysis model, so as to improve the traceability to the final product from the valid requirements analysis model. This paper discusses the result of applying our method to the development of a Group Work Support System that is currently running in our department. PMID:23565356

  14. 45 CFR 162.915 - Trading partner agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Trading partner agreements. 162.915 Section 162... REQUIREMENTS ADMINISTRATIVE REQUIREMENTS General Provisions for Transactions § 162.915 Trading partner agreements. A covered entity must not enter into a trading partner agreement that would do any of...

  15. 42 CFR 431.108 - Effective date of provider agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... perform. (b) All requirements are met on the date of survey. The agreement is effective on the date the... 42 Public Health 4 2010-10-01 2010-10-01 false Effective date of provider agreements. 431.108... Administrative Requirements: Provider Relations § 431.108 Effective date of provider agreements....

  16. 48 CFR 752.7005 - Submission requirements for development experience documents.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Submission requirements for development experience documents. 752.7005 Section 752.7005 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of USAID Contract Clauses...

  17. 26 CFR 1.1248-5 - Stock ownership requirements for less developed country corporations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... country corporations. 1.1248-5 Section 1.1248-5 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF... Gains and Losses § 1.1248-5 Stock ownership requirements for less developed country corporations. (a... foreign corporation X, a less developed country corporation. On December 31, 1964, N recognizes gain...

  18. 26 CFR 1.1248-5 - Stock ownership requirements for less developed country corporations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... country corporations. 1.1248-5 Section 1.1248-5 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF... Capital Gains and Losses § 1.1248-5 Stock ownership requirements for less developed country corporations... foreign corporation X, a less developed country corporation. On December 31, 1964, N recognizes gain...

  19. Teacher Perceptions of Professional Development Required by the Wisconsin Quality Educator Initiative, PI 34

    ERIC Educational Resources Information Center

    Sixel, Deborah Marie

    2013-01-01

    Existing research has shown an association between teachers' professional growth and student success. However, there is a lack of information on the mandated professional development linked to Wisconsin teacher licensure requirements. The purpose of this study was to examine the phenomenon of self-directed professional development and its…

  20. Using Work Action Analysis to Identify Web-Portal Requirements for a Professional Development Program

    ERIC Educational Resources Information Center

    Nickles, George

    2007-01-01

    This article describes using Work Action Analysis (WAA) as a method for identifying requirements for a web-based portal that supports a professional development program. WAA is a cognitive systems engineering method for modeling multi-agent systems to support design and evaluation. A WAA model of the professional development program of the…

  1. Condition monitoring requirements for the development of a space nuclear propulsion module

    NASA Technical Reports Server (NTRS)

    Wagner, Robert C.

    1993-01-01

    To facilitate the development of a space nuclear propulsion module for manned flights to Mars, requirements must be established early in the technology cycle. The long lead times for the acquisition of the engine system and nuclear test facilities demands that the engine system, size, performance, safety goals and condition monitoring philosophy be defined at the earliest possible time. These systems are highly complex and require a large multi-disciplinary systems engineering team to develop and track the requirements and to ensure that the as-built system reflects the intent of the mission. An effective methodology has been devised coupled with sophisticated computer tools to effectivly develop and interpret the functional requirements. These requirements can then be decomposed down to the specification level for implementation. This paper discusses the application of the methodology and the analyses to develop condition monitoring requirements under a contract with the National Aeronautics and Space Administration (NASA) Lewis Research Center (LeRC) Nuclear Propulsion Office (NPO).

  2. A Scenario-Based Process for Requirements Development: Application to Mission Operations Systems

    NASA Technical Reports Server (NTRS)

    Bindschadler, Duane L.; Boyles, Carole A.

    2008-01-01

    The notion of using operational scenarios as part of requirements development during mission formulation (Phases A & B) is widely accepted as good system engineering practice. In the context of developing a Mission Operations System (MOS), there are numerous practical challenges to translating that notion into the cost-effective development of a useful set of requirements. These challenges can include such issues as a lack of Project-level focus on operations issues, insufficient or improper flowdown of requirements, flowdown of immature or poor-quality requirements from Project level, and MOS resource constraints (personnel expertise and/or dollars). System engineering theory must be translated into a practice that provides enough structure and standards to serve as guidance, but that retains sufficient flexibility to be tailored to the needs and constraints of a particular MOS or Project. We describe a detailed, scenario-based process for requirements development. Identifying a set of attributes for high quality requirements, we show how the portions of the process address many of those attributes. We also find that the basic process steps are robust, and can be effective even in challenging Project environments.

  3. Space transfer vehicle concepts and requirements study. Volume 2, book 4: Integrated advanced technology development

    NASA Technical Reports Server (NTRS)

    Weber, Gary A.

    1991-01-01

    The Space Transfer Vehicle (STV) program provides both an opportunity and a requirement to increase our upper stage capabilities with the development and applications of new technologies. Issues such as man rating, space basing, reusability, and long lunar surface storage times drive the need for new technology developments and applications. In addition, satisfaction of mission requirements such as lunar cargo delivery capability and lunar landing either require new technology development or can be achieved in a more cost-effective manner with judicious applications of advanced technology. During the STV study, advanced technology development requirements and plans have been addressed by the Technology/Advanced Development Working Group composed of NASA and contractor representatives. This report discusses the results to date of this working group. The first section gives an overview of the technologies that have potential or required applications for the STV and identifies those technologies baselined for the STV. Figures are provided that list the technology categories and show the priority placed on those technology categories for either the space-based or ground-based options. The second section covers the plans and schedules for incorporating the technologies into the STV program.

  4. Coal liquefaction processes and development requirements analysis for synthetic fuels production

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Focus of the study is on: (1) developing a technical and programmatic data base on direct and indirect liquefaction processes which have potential for commercialization during the 1980's and beyond, and (2) performing analyses to assess technology readiness and development trends, development requirements, commercial plant costs, and projected synthetic fuel costs. Numerous data sources and references were used as the basis for the analysis results and information presented.

  5. TOPEX Project Radar Altimeter Development Requirements and Specifications, Version 6.0

    NASA Technical Reports Server (NTRS)

    Rossi, Laurence C.

    2003-01-01

    This document provides the guidelines by which the TOPEX Radar Altimeter hardware development effort for the TOPEX flight project shall be implemented and conducted. The conduct of this activity shall take maximum advantage of the efforts expended during the TOPEX Radar Altimeter Advanced Technology Model development program and other related Radar Altimeter development efforts. This document complies with the TOPEX Project Office document 633-420 (D-2218), entitled, "TOPEX Project Requirements and Constraints for the NASA Radar Altimeter" dated December 1987.

  6. An agreement coefficient for image comparison

    USGS Publications Warehouse

    Ji, L.; Gallo, K.

    2006-01-01

    Combination of datasets acquired from different sensor systems is necessary to construct a long time-series dataset for remotely sensed land-surface variables. Assessment of the agreement of the data derived from various sources is an important issue in understanding the data continuity through the time-series. Some traditional measures, including correlation coefficient, coefficient of determination, mean absolute error, and root mean square error, are not always optimal for evaluating the data agreement. For this reason, we developed a new agreement coefficient for comparing two different images. The agreement coefficient has the following properties: non-dimensional, bounded, symmetric, and distinguishable between systematic and unsystematic differences. The paper provides examples of agreement analyses for hypothetical data and actual remotely sensed data. The results demonstrate that the agreement coefficient does include the above properties, and therefore is a useful tool for image comparison. ?? 2006 American Society for Photogrammetry and Remote Sensing.

  7. 12 CFR 1807.900 - Assistance agreement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 9 2012-01-01 2012-01-01 false Assistance agreement. 1807.900 Section 1807.900 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY CAPITAL MAGNET FUND Terms and Conditions of Assistance § 1807.900 Assistance agreement. (a) Each Applicant...

  8. 12 CFR 1807.900 - Assistance agreement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 9 2013-01-01 2013-01-01 false Assistance agreement. 1807.900 Section 1807.900 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY CAPITAL MAGNET FUND Terms and Conditions of Assistance § 1807.900 Assistance agreement. (a) Each Applicant...

  9. 12 CFR 1807.900 - Assistance agreement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Assistance agreement. 1807.900 Section 1807.900 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY CAPITAL MAGNET FUND Terms and Conditions of Assistance § 1807.900 Assistance agreement. (a) Each...

  10. 12 CFR 1807.900 - Assistance agreement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 7 2011-01-01 2011-01-01 false Assistance agreement. 1807.900 Section 1807.900 Banks and Banking COMMUNITY DEVELOPMENT FINANCIAL INSTITUTIONS FUND, DEPARTMENT OF THE TREASURY CAPITAL MAGNET FUND Terms and Conditions of Assistance § 1807.900 Assistance agreement. (a) Each Applicant...

  11. 30 CFR 735.19 - Grant agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 3 2013-07-01 2013-07-01 false Grant agreement. 735.19 Section 735.19 Mineral... REGULATORY PROGRAMS FOR NON-FEDERAL AND NON-INDIAN LANDS GRANTS FOR PROGRAM DEVELOPMENT AND ADMINISTRATION AND ENFORCEMENT § 735.19 Grant agreement. (a) If the Director or his authorized designee approves...

  12. 30 CFR 735.19 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Grant agreement. 735.19 Section 735.19 Mineral... REGULATORY PROGRAMS FOR NON-FEDERAL AND NON-INDIAN LANDS GRANTS FOR PROGRAM DEVELOPMENT AND ADMINISTRATION AND ENFORCEMENT § 735.19 Grant agreement. (a) If the Director or his authorized designee approves...

  13. 30 CFR 735.19 - Grant agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Grant agreement. 735.19 Section 735.19 Mineral... REGULATORY PROGRAMS FOR NON-FEDERAL AND NON-INDIAN LANDS GRANTS FOR PROGRAM DEVELOPMENT AND ADMINISTRATION AND ENFORCEMENT § 735.19 Grant agreement. (a) If the Director or his authorized designee approves...

  14. Growth requirements for multidiscipline research and development on the evolutionary space station

    NASA Technical Reports Server (NTRS)

    Meredith, Barry; Ahlf, Peter; Saucillo, Rudy; Eakman, David

    1988-01-01

    The NASA Space Station Freedom is being designed to facilitate on-orbit evolution and growth to accommodate changing user needs and future options for U.S. space exploration. In support of the Space Station Freedom Program Preliminary Requirements Review, The Langley Space Station Office has identified a set of resource requirements for Station growth which is deemed adequate for the various evolution options. As part of that effort, analysis was performed to scope requirements for Space Station as an expanding, multidiscipline facility for scientific research, technology development and commercial production. This report describes the assumptions, approach and results of the study.

  15. Manned remote work station development article. Volume 3: Development test plan. Appendix A: Manufacturing requirements/schedule

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The tests and procedures for the manned remote work station (MRWS) open cherry picker (OCP) development test article (DTA) are described to validate systems requirements and performance specifications. A development test program is outlined to evaluate key design issues and man/machine interfaces when the MRWS OCP is used in a shuttle support role of satellite servicing and in orbit construction of large structures.

  16. The Toll pathway is required in the epidermis for muscle development in the Drosophila embryo

    NASA Technical Reports Server (NTRS)

    Halfon, M. S.; Keshishian, H.

    1998-01-01

    The Toll signaling pathway functions in several Drosophila processes, including dorsal-ventral pattern formation and the immune response. Here, we demonstrate that this pathway is required in the epidermis for proper muscle development. Previously, we showed that the zygotic Toll protein is necessary for normal muscle development; in the absence of zygotic Toll, close to 50% of hemisegments have muscle patterning defects consisting of missing, duplicated and misinserted muscle fibers (Halfon, M.S., Hashimoto, C., and Keshishian, H., Dev. Biol. 169, 151-167, 1995). We have now also analyzed the requirements for easter, spatzle, tube, and pelle, all of which function in the Toll-mediated dorsal-ventral patterning pathway. We find that spatzle, tube, and pelle, but not easter, are necessary for muscle development. Mutations in these genes give a phenotype identical to that seen in Toll mutants, suggesting that elements of the same pathway used for Toll signaling in dorsal-ventral development are used during muscle development. By expressing the Toll cDNA under the control of distinct Toll enhancer elements in Toll mutant flies, we have examined the spatial requirements for Toll expression during muscle development. Expression of Toll in a subset of epidermal cells that includes the epidermal muscle attachment cells, but not Toll expression in the musculature, is necessary for proper muscle development. Our results suggest that signals received by the epidermis early during muscle development are an important part of the muscle patterning process.

  17. Pitx3 is required for development of substantia nigra dopaminergic neurons

    PubMed Central

    Nunes, Irene; Tovmasian, Lucy T.; Silva, Robert M.; Burke, Robert E.; Goff, Stephen P.

    2003-01-01

    Dopaminergic (DA) neurons of substantia nigra in the midbrain control voluntary movement, and their degeneration is the cause of Parkinson's disease. The complete set of genes required to specifically determine the development of midbrain DA subgroups is not known yet. We report here that mice lacking the bicoid-related homeoprotein Pitx3 fail to develop DA neurons of the substantia nigra. Other mesencephalic DA neurons of the ventral tegmental area and retrorubral field are unaltered in their dopamine expression and histological organization. These data suggest that Pitx3-dependent gene expression is specifically required for the differentiation of DA progenitors within the mesencephalic DA system. PMID:12655058

  18. The UIC ICBG (University of Illinois at Chicago International Cooperative Biodiversity Group) Memorandum of Agreement: a model of benefit-sharing arrangement in natural products drug discovery and development.

    PubMed

    Soejarto, D D; Gyllenhaal, C; Fong, H H S; Xuan, L T; Hiep, N T; Hung, N V; Bich, T Q; Southavong, B; Sydara, K; Pezzuto, J M

    2004-02-01

    The Convention on Biodiversity mandates a new approach to the discovery of natural product drugs, one that incorporates concepts of national ownership of genetic resources, intellectual property rights in traditional knowledge, and sharing of economic benefits with countries that are the source of new natural products. The International Cooperative Biodiversity Group (ICBG) program was established to support experimentation in implementation of the Convention through development and execution of international agreements for bioprospecting. The agreement of one such ICBG program, between the University of Illinois at Chicago and institutions in Vietnam and Laos, is presented here. The core elements contained in the single, five-way Memorandum of Agreement are the arrangements for intellectual property rights, treatment of informed consent, and plans for benefit-sharing (including the sharing of short- and long-term royalty benefits, capacity building, and community reciprocity). Program participants were able to develop a practical and flexible agreement that satisfies the wishes of all institutions that are parties to it. PMID:14987071

  19. Mandatory continuing professional development requirements: what does this mean for Australian nurses

    PubMed Central

    2013-01-01

    Background This paper presents a discussion related to the recent decision in Australia to introduce mandatory Continuing Professional Development (CPD) for nurses. Historically there has been international debate surrounding mandatory CPD requirements; this debate is ongoing as Australian nurses face a diverse range of CPD offerings from a variety of providers. Discussion The purpose of this paper is to examine how mandatory CPD requirements for national nursing registration in Australia have evolved and to present an analysis of what this will mean for Australian nurses. What is yet to be determined is how to measure professional development and the effectiveness of professional development education. This is important to the international community with consensus in the literature that professional development is linked to ongoing education. Contradicting arguments are presented about whether this professional development should be mandatory. Summary Presenting a contemporary discussion about the current and potential impact of mandatory CPD requirements for nurses, this discussion paper utilises the case of Australia’s current national policy and CPD operation to examine the choices that nurses make in order to fulfil their legislative requirements. Additional arguments are presented about the barriers nurses face in undertaking CPD. The quest for effective CPD is complex and should incorporate different situations for nurses and individual learning styles. PMID:23537293

  20. Tissue-specific requirements of beta-catenin in external genitalia development.

    PubMed

    Lin, Congxing; Yin, Yan; Long, Fanxin; Ma, Liang

    2008-08-01

    External genitalia are body appendages specialized for internal fertilization. Their development can be divided into two phases, an early androgen-independent phase and a late androgen-dependent sexual differentiation phase. In the early phase, the embryonic anlage of external genitalia, the genital tubercle (GT), is morphologically identical in both sexes. Although congenital external genitalia malformations represent the second most common birth defect in humans, the genetic pathways governing early external genitalia development and urethra formation are poorly understood. Proper development of the GT requires coordinated outgrowth of the mesodermally derived mesenchyme and extension of the endodermal urethra within an ectodermal epithelial capsule. Here, we demonstrate that beta-catenin plays indispensable and distinct roles in each of the aforementioned three tissue layers in early androgen-independent GT development. WNT-beta-catenin signaling is required in the endodermal urethra to activate and maintain Fgf8 expression and direct GT outgrowth, as well as to maintain homeostasis of the urethra. Moreover, beta-catenin is required in the mesenchyme to promote cell proliferation. By contrast, beta-catenin is required in the ectoderm to maintain tissue integrity, possibly through cell-cell adhesion during GT outgrowth. The fact that both endodermal and ectodermal beta-catenin knockout animals develop severe hypospadias in both sexes raises the possibility that the deregulation of any of these functions can contribute to the etiology of congenital external genital defects in humans. PMID:18635608

  1. 24 CFR 583.400 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 3 2012-04-01 2012-04-01 false Grant agreement. 583.400 Section 583.400 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR COMMUNITY PLANNING AND DEVELOPMENT, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT COMMUNITY FACILITIES...

  2. 24 CFR 585.402 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 3 2012-04-01 2012-04-01 false Grant agreement. 585.402 Section 585.402 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR COMMUNITY PLANNING AND DEVELOPMENT, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT COMMUNITY FACILITIES...

  3. 24 CFR 582.400 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 3 2012-04-01 2012-04-01 false Grant agreement. 582.400 Section 582.400 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR COMMUNITY PLANNING AND DEVELOPMENT, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT COMMUNITY FACILITIES SHELTER...

  4. Virtual environment and computer-aided technologies used for system prototyping and requirements development

    NASA Technical Reports Server (NTRS)

    Logan, Cory; Maida, James; Goldsby, Michael; Clark, Jim; Wu, Liew; Prenger, Henk

    1993-01-01

    The Space Station Freedom (SSF) Data Management System (DMS) consists of distributed hardware and software which monitor and control the many onboard systems. Virtual environment and off-the-shelf computer technologies can be used at critical points in project development to aid in objectives and requirements development. Geometric models (images) coupled with off-the-shelf hardware and software technologies were used in The Space Station Mockup and Trainer Facility (SSMTF) Crew Operational Assessment Project. Rapid prototyping is shown to be a valuable tool for operational procedure and system hardware and software requirements development. The project objectives, hardware and software technologies used, data gained, current activities, future development and training objectives shall be discussed. The importance of defining prototyping objectives and staying focused while maintaining schedules are discussed along with project pitfalls.

  5. University-Industry Teaming Agreements.

    ERIC Educational Resources Information Center

    Stombler, Milton P.

    1989-01-01

    The use of preaward agreements between the industry and the university collaborating to seek external funding, particularly from government sources, is examined. The agreements describe the parties' obligations in seeking funding and lay the groundwork for subsequent research agreements. Elements of such agreements are discussed to raise awareness…

  6. 23 CFR 630.108 - Preparation of agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... PRECONSTRUCTION PROCEDURES Project Authorization and Agreements § 630.108 Preparation of agreement. (a) The STD shall prepare a project agreement for each Federal-aid project. (b) The STD may develop the project agreement in a format acceptable to both the STD and the FHWA provided the following are included: (1)...

  7. 23 CFR 630.108 - Preparation of agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... PRECONSTRUCTION PROCEDURES Project Authorization and Agreements § 630.108 Preparation of agreement. (a) The STD shall prepare a project agreement for each Federal-aid project. (b) The STD may develop the project agreement in a format acceptable to both the STD and the FHWA provided the following are included: (1)...

  8. 23 CFR 630.108 - Preparation of agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... PRECONSTRUCTION PROCEDURES Project Authorization and Agreements § 630.108 Preparation of agreement. (a) The STD shall prepare a project agreement for each Federal-aid project. (b) The STD may develop the project agreement in a format acceptable to both the STD and the FHWA provided the following are included: (1)...

  9. Improving the Communication Skills of IS Developers during Requirements Elicitation Using Experiential Learning

    ERIC Educational Resources Information Center

    Qurban, Mustafa H.; Austria, Richmond D.

    2009-01-01

    The improvement of communication skills among Information Systems (IS) developers can be considered as a strategy to mitigate the risk of project failure during IS design. This paper addresses issues on various communication barriers normally encountered during its requirements elicitation (RE) stage. This study aims to adopt experiential learning…

  10. 40 CFR 256.62 - Requirements for public participation in State regulatory development.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Public Participation § 256.62 Requirements for public participation in State regulatory... summary shall be prepared and made available to the public in accord with 40 CFR 25.8. (b) In advance...

  11. 40 CFR 256.62 - Requirements for public participation in State regulatory development.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Public Participation § 256.62 Requirements for public participation in State regulatory... summary shall be prepared and made available to the public in accord with 40 CFR 25.8. (b) In advance...

  12. 40 CFR 256.62 - Requirements for public participation in State regulatory development.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Public Participation § 256.62 Requirements for public participation in State regulatory... summary shall be prepared and made available to the public in accord with 40 CFR 25.8. (b) In advance...

  13. Estimating N requirements for corn using indices developed from a canopy reflectance sensor

    Technology Transfer Automated Retrieval System (TEKTRAN)

    With the increasing cost of fertilizer N, there is a renewed emphasis on developing new technologies for quantifying in-season N requirements for corn. The objectives of this research are (i) to evaluate different vegetative indices derived from an active reflectance sensor in estimating in-season N...

  14. CD34 EXPRESSION BY HAIR FOLLICLE STEM CELLS IS REQUIRED FOR SKIN TUMOR DEVELOPMENT IN MICE

    EPA Science Inventory

    We used knockout mice to show that a cell surface protein called CD34 is required for skin tumor formation in mice. Wild type mice treated with 7-12-Dimethylbenz(a)anthracene (DMBA) and a tumor promoter developed papillomas. When we treated CD34 knockout (KO) mice the same way, n...

  15. The Professional Development Requirements of Workplace English Language and Literacy Programme Practitioners: Support Document

    ERIC Educational Resources Information Center

    Berghella, Tina; Molenaar, John; Wyse, Linda

    2006-01-01

    This support document was produced by the authors based on their research for the report, "The Professional Development Requirements of Workplace English Language and Literacy Programme Practitioners," [ED495200] and is an added resource for further information. The original report examines the extent and nature of professional development…

  16. 34 CFR 364.24 - What assurances are required for staff development?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false What assurances are required for staff development? 364.24 Section 364.24 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION STATE INDEPENDENT...

  17. 34 CFR 364.24 - What assurances are required for staff development?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true What assurances are required for staff development? 364.24 Section 364.24 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION STATE INDEPENDENT...

  18. An end-to-end approach to developing biological and chemical detector requirements

    NASA Astrophysics Data System (ADS)

    Teclemariam, Nerayo P.; Purvis, Liston K.; Foltz, Greg W.; West, Todd; Edwards, Donna M.; Fruetel, Julia A.; Gleason, Nathaniel J.

    2009-05-01

    Effective defense against chemical and biological threats requires an "end-to-end" strategy that encompasses the entire problem space, from threat assessment and target hardening to response planning and recovery. A key element of the strategy is the definition of appropriate system requirements for surveillance and detection of threat agents. Our end-to-end approach to venue chem/bio defense is captured in the Facilities Weapons of Mass Destruction Decision Analysis Capability (FacDAC), an integrated system-of-systems toolset that can be used to generate requirements across all stages of detector development. For example, in the early stage of detector development the approach can be used to develop performance targets (e.g., sensitivity, selectivity, false positive rate) to provide guidance on what technologies to pursue. In the development phase, after a detector technology has been selected, the approach can aid in determining performance trade-offs and down-selection of competing technologies. During the application stage, the approach can be employed to design optimal defensive architectures that make the best use of available technology to maximize system performance. This presentation will discuss the end-to-end approach to defining detector requirements and demonstrate the capabilities of the FacDAC toolset using examples from a number of studies for the Department of Homeland Security.

  19. A Framework for Assessing Continuing Professional Development Activities for Satisfying Pharmacy Revalidation Requirements

    ERIC Educational Resources Information Center

    Donyai, Parastou; Alexander, Angela M.; Denicolo, Pam M.

    2013-01-01

    Introduction: The United Kingdom's pharmacy regulator contemplated using continuing professional development (CPD) in pharmacy revalidation in 2009, simultaneously asking pharmacy professionals to demonstrate the value of their CPD by showing its relevance and impact. The idea of linking new CPD requirements with revalidation was yet to be…

  20. ModSAF-based development of operational requirements for light armored vehicles

    NASA Astrophysics Data System (ADS)

    Rapanotti, John; Palmarini, Marc

    2003-09-01

    Light Armoured Vehicles (LAVs) are being developed to meet the modern requirements of rapid deployment and operations other than war. To achieve these requirements, passive armour is minimized and survivability depends more on sensors, computers, countermeasures and communications to detect and avoid threats. The performance, reliability, and ultimately the cost of these systems, will be determined by the technology trends and the rates at which they mature. Defining vehicle requirements will depend upon an accurate assessment of these trends over a longer term than was previously needed. Modelling and simulation are being developed to study these long-term trends and how they contribute to establishing vehicle requirements. ModSAF is being developed for research and development, in addition to the original requirement of Simulation and Modelling for Acquisition, Rehearsal, Requirements and Training (SMARRT), and is becoming useful as a means for transferring technology to other users, researchers and contractors. This procedure eliminates the need to construct ad hoc models and databases. The integration of various technologies into a Defensive Aids Suite (DAS) can be designed and analyzed by combining field trials and laboratory data with modelling and simulation. ModSAF (Modular Semi-Automated Forces,) is used to construct the virtual battlefield and, through scripted input files, a "fixed battle" approach is used to define and implement contributions from three different sources. These contributions include: models of technology and natural phenomena from scientists and engineers, tactics and doctrine from the military and detailed analyses from operations research. This approach ensures the modelling of processes known to be important regardless of the level of information available about the system. Survivability of DAS-equipped vehicles based on future and foreign technology can be investigated by ModSAF and assessed relative to a test vehicle. A vehicle can

  1. 45 CFR 630.620 - Cooperative agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION... carrying out the activity contemplated by the award. The term does not include cooperative research and development agreements as defined in 15 U.S.C. 3710a....

  2. 24 CFR 972.106 - Procedure for required conversion of public housing developments to tenant-based assistance.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Procedure for required conversion... FOR PUBLIC AND INDIAN HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT CONVERSION OF PUBLIC HOUSING TO TENANT-BASED ASSISTANCE Required Conversion of Public Housing Developments Required...

  3. The zinc finger transcription factor 191 is required for early embryonic development and cell proliferation

    SciTech Connect

    Li Jianzhong; Chen Xia; Yang Hua; Wang Shuiliang; Guo Baoyu; Yu Long; Wang Zhugang; Fu Jiliang . E-mail: fu825@mail.tongji.edu.cn

    2006-12-10

    Human zinc finger protein 191 (ZNF191/ZNF24) was cloned and characterized as a SCAN family member, which shows 94% identity to its mouse homologue zinc finger protein 191 (Zfp191). ZNF191 can specifically interact with an intronic polymorphic TCAT repeat (HUMTH01) in the tyrosine hydroxylase (TH) gene. Allelic variations of HUMTH01 have been stated to have a quantitative silencing effect on TH gene expression and to correlate with quantitative and qualitative changes in the binding by ZNF191. Zfp191 is widely expressed during embryonic development and in multiple tissues and organs in adult. To investigate the functions of Zfp191 in vivo, we have used homologous recombination to generate mice that are deficient in Zfp191. Heterozygous Zfp191 {sup +/-} mice are normal and fertile. Homozygous Zfp191 {sup -/-} embryos are severely retarded in development and die at approximately 7.5 days post-fertilization. Unexpectedly, in Zfp191 {sup -/-} and Zfp191 {sup +/-} embryos, TH gene expression is not affected. Blastocyst outgrowth experiments and the RNA interference-mediated knockdown of ZNF191 in cultured cells revealed an essential role for Zfp191 in cell proliferation. In further agreement with this function, no viable Zfp191 {sup -/-} cell lines were obtained by derivation of embryonic stem (ES) cells from blastocysts of Zfp191 {sup +/-} intercrosses or by forced homogenotization of heterozygous ES cells at high concentrations of G418. These data show that Zfp191 is indispensable for early embryonic development and cell proliferation.

  4. Food and oxygen requirements for growing mice and turtles after hypergravitational development.

    PubMed

    Wunder, C C; Dodge, C H; Cook, K M; Moressi, W J

    1977-01-01

    Although development of mice and turtles, both low-payload animals, can be influenced by ambient gravitational intensity, little is known regarding the influence of either their growth or their gravitational history upon life-support requirements. A 25-g male Box Turtle (Terrapene carolina, optimally growing at 30 degrees C and 1 G to double its size in 7 weeks) exhibits daily requirements of oxygen (100 ml) and food (200 mg, dry) which are only 3% of the requirement for a mouse (Swiss Webster, centrifuged at 22 degrees) of comparable size and growth rate. These requirements grow in proportion to the turtle's (body mass)0.9 and to the mouse's (body mass)0.5. After development at hypergravity g (of from 1.5 to 5 G expressed in multiples of the earth's gravity) there is a one-day delay for turtles but an immediate change for mice in these requirements upon return to 1 G. Although both show a decreased oxygen intake, the drop is greater for turtles (equalling g -0.4 of the baseline value, as corrected for body size, after return from 75 days exposure against g-0.08 for mice after 1-13 days exposure); the food intake drops for turtles (varies as g-1) while it rises for mice (varies as g0.6). PMID:11962496

  5. Department of Energy Environmental Management cost infrastructure development program: Cost analysis requirements

    SciTech Connect

    Custer, W.R. Jr.; Messick, C.D.

    1996-03-31

    This report was prepared to support development of the Department of Energy Environmental Management cost infrastructure -- a new capability to independently estimate and analyze costs. Currently, the cost data are reported according to a structure that blends level of effort tasks with product and process oriented tasks. Also. the budgetary inputs are developed from prior year funding authorizations and from contractor-developed parametric estimates that have been adjusted to planned funding levels or appropriations. Consequently, it is difficult for headquarters and field-level activities to use actual cost data and technical requirements to independently assess the costs generated and identify trends, potential cost savings from process improvements, and cost reduction strategies.

  6. Mission simulation as an approach to develop requirements for automation in Advanced Life Support Systems

    NASA Technical Reports Server (NTRS)

    Erickson, J. D.; Eckelkamp, R. E.; Barta, D. J.; Dragg, J.; Henninger, D. L. (Principal Investigator)

    1996-01-01

    This paper examines mission simulation as an approach to develop requirements for automation and robotics for Advanced Life Support Systems (ALSS). The focus is on requirements and applications for command and control, control and monitoring, situation assessment and response, diagnosis and recovery, adaptive planning and scheduling, and other automation applications in addition to mechanized equipment and robotics applications to reduce the excessive human labor requirements to operate and maintain an ALSS. Based on principles of systems engineering, an approach is proposed to assess requirements for automation and robotics using mission simulation tools. First, the story of a simulated mission is defined in terms of processes with attendant types of resources needed, including options for use of automation and robotic systems. Next, systems dynamics models are used in simulation to reveal the implications for selected resource allocation schemes in terms of resources required to complete operational tasks. The simulations not only help establish ALSS design criteria, but also may offer guidance to ALSS research efforts by identifying gaps in knowledge about procedures and/or biophysical processes. Simulations of a planned one-year mission with 4 crewmembers in a Human Rated Test Facility are presented as an approach to evaluation of mission feasibility and definition of automation and robotics requirements.

  7. 24 CFR 200.50 - Building loan agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Building loan agreement. 200.50 Section 200.50 Housing and Urban Development Regulations Relating to Housing and Urban Development... Building loan agreement. The mortgagor and mortgagee must execute a building loan agreement approved by...

  8. 24 CFR 200.50 - Building loan agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Building loan agreement. 200.50 Section 200.50 Housing and Urban Development Regulations Relating to Housing and Urban Development... Building loan agreement. The mortgagor and mortgagee must execute a building loan agreement approved by...

  9. 24 CFR 200.50 - Building loan agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Building loan agreement. 200.50 Section 200.50 Housing and Urban Development Regulations Relating to Housing and Urban Development... Building loan agreement. The mortgagor and mortgagee must execute a building loan agreement approved by...

  10. 24 CFR 200.50 - Building loan agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Building loan agreement. 200.50 Section 200.50 Housing and Urban Development Regulations Relating to Housing and Urban Development... Building loan agreement. The mortgagor and mortgagee must execute a building loan agreement approved by...

  11. 24 CFR 200.50 - Building loan agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Building loan agreement. 200.50 Section 200.50 Housing and Urban Development Regulations Relating to Housing and Urban Development... Building loan agreement. The mortgagor and mortgagee must execute a building loan agreement approved by...

  12. 24 CFR 700.140 - Participatory agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Participatory agreement. 700.140 Section 700.140 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF THE SECRETARY, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT (HOUSING ASSISTANCE...

  13. 24 CFR 241.635 - Regulatory agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Regulatory agreement. 241.635 Section 241.635 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MORTGAGE AND LOAN...

  14. 24 CFR 241.635 - Regulatory agreement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Regulatory agreement. 241.635 Section 241.635 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MORTGAGE AND LOAN...

  15. 24 CFR 582.400 - Grant agreement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Grant agreement. 582.400 Section 582.400 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR COMMUNITY PLANNING AND DEVELOPMENT, DEPARTMENT OF HOUSING AND...

  16. 24 CFR 585.402 - Grant agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 3 2013-04-01 2013-04-01 false Grant agreement. 585.402 Section 585.402 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR COMMUNITY PLANNING AND DEVELOPMENT, DEPARTMENT OF HOUSING AND...

  17. 24 CFR 582.400 - Grant agreement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 3 2013-04-01 2013-04-01 false Grant agreement. 582.400 Section 582.400 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR COMMUNITY PLANNING AND DEVELOPMENT, DEPARTMENT OF HOUSING AND...

  18. 24 CFR 582.400 - Grant agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 3 2011-04-01 2010-04-01 true Grant agreement. 582.400 Section 582.400 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR COMMUNITY PLANNING AND DEVELOPMENT, DEPARTMENT OF HOUSING AND...

  19. 24 CFR 280.30 - Grant agreement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Grant agreement. 280.30 Section 280.30 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... DEVELOPMENT GRANT PROGRAMS NEHEMIAH HOUSING OPPORTUNITY GRANTS PROGRAM Program Operation § 280.30...

  20. 24 CFR 280.30 - Grant agreement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Grant agreement. 280.30 Section 280.30 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... DEVELOPMENT GRANT PROGRAMS NEHEMIAH HOUSING OPPORTUNITY GRANTS PROGRAM Program Operation § 280.30...